LOCUS       DACGDM010000001       128976 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.001, whole genome shotgun sequence.
ACCESSION   DACGDM010000001 DACGDM010000000
VERSION     DACGDM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 128976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.001"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(12..1535)
                     /locus_tag="IXR05_000001"
     CDS             complement(12..1535)
                     /locus_tag="IXR05_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAQ4258555.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            1787..2968
                     /locus_tag="IXR05_000002"
     CDS             1787..2968
                     /locus_tag="IXR05_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4258556.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(3028..4656)
                     /gene="treC"
                     /locus_tag="IXR05_000003"
     CDS             complement(3028..4656)
                     /gene="treC"
                     /locus_tag="IXR05_000003"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAQ4258557.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGENMSEGNGWNALFFNNHDQPRALNRFVVIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(5053..7764)
                     /locus_tag="IXR05_000004"
     CDS             complement(5053..7764)
                     /locus_tag="IXR05_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4258558.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLPQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7774..8475)
                     /locus_tag="IXR05_000005"
     CDS             complement(7774..8475)
                     /locus_tag="IXR05_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258559.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8661..9260
                     /locus_tag="IXR05_000006"
     CDS             8661..9260
                     /locus_tag="IXR05_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4258560.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTIKKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9341..10354
                     /locus_tag="IXR05_000007"
     CDS             9341..10354
                     /locus_tag="IXR05_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4258561.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10462..11379
                     /gene="rbsK"
                     /locus_tag="IXR05_000008"
     CDS             10462..11379
                     /gene="rbsK"
                     /locus_tag="IXR05_000008"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAQ4258562.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11407..11802
                     /gene="rbsD"
                     /locus_tag="IXR05_000009"
     CDS             11407..11802
                     /gene="rbsD"
                     /locus_tag="IXR05_000009"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAQ4258563.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11802..13175
                     /locus_tag="IXR05_000010"
     CDS             11802..13175
                     /locus_tag="IXR05_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4258564.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13532..15676
                     /locus_tag="IXR05_000011"
     CDS             13532..15676
                     /locus_tag="IXR05_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4258565.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(15728..16768)
                     /locus_tag="IXR05_000012"
     CDS             complement(15728..16768)
                     /locus_tag="IXR05_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4258566.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMGNGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(17045..18847)
                     /locus_tag="IXR05_000013"
     CDS             complement(17045..18847)
                     /locus_tag="IXR05_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258567.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIILGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18861..19613)
                     /locus_tag="IXR05_000014"
     CDS             complement(18861..19613)
                     /locus_tag="IXR05_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258568.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19622..19984)
                     /locus_tag="IXR05_000015"
     CDS             complement(19622..19984)
                     /locus_tag="IXR05_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4258569.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20160..21032)
                     /locus_tag="IXR05_000016"
     CDS             complement(20160..21032)
                     /locus_tag="IXR05_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAQ4258570.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21058..21570)
                     /locus_tag="IXR05_000017"
     CDS             complement(21058..21570)
                     /locus_tag="IXR05_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAQ4258571.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQARGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            complement(21708..22538)
                     /locus_tag="IXR05_000018"
     CDS             complement(21708..22538)
                     /locus_tag="IXR05_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAQ4258572.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            complement(22554..23162)
                     /locus_tag="IXR05_000019"
     CDS             complement(22554..23162)
                     /locus_tag="IXR05_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAQ4258573.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23155..23472)
                     /locus_tag="IXR05_000020"
     CDS             complement(23155..23472)
                     /locus_tag="IXR05_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4258574.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23628..24356)
                     /locus_tag="IXR05_000021"
     CDS             complement(23628..24356)
                     /locus_tag="IXR05_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAQ4258575.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24515..25396
                     /locus_tag="IXR05_000022"
     CDS             24515..25396
                     /locus_tag="IXR05_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4258576.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARNFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25633..26676)
                     /locus_tag="IXR05_000023"
     CDS             complement(25633..26676)
                     /locus_tag="IXR05_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4258577.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIG
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26679..27347)
                     /locus_tag="IXR05_000024"
     CDS             complement(26679..27347)
                     /locus_tag="IXR05_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4258578.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27489..29825
                     /locus_tag="IXR05_000025"
     CDS             27489..29825
                     /locus_tag="IXR05_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4258579.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29940..30251)
                     /locus_tag="IXR05_000026"
     CDS             complement(29940..30251)
                     /locus_tag="IXR05_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258580.1"
                     /translation="MKKMKESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30432..31907
                     /locus_tag="IXR05_000027"
     CDS             30432..31907
                     /locus_tag="IXR05_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAQ4258581.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31954..32538
                     /locus_tag="IXR05_000028"
     CDS             31954..32538
                     /locus_tag="IXR05_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAQ4258582.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            32540..32959
                     /locus_tag="IXR05_000029"
     CDS             32540..32959
                     /locus_tag="IXR05_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAQ4258583.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKTL"
     gene            complement(33240..33524)
                     /locus_tag="IXR05_000030"
     CDS             complement(33240..33524)
                     /locus_tag="IXR05_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAQ4258584.1"
                     /translation="MREIYSFESKIYASEVDKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNMPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33876..34586)
                     /locus_tag="IXR05_000031"
     CDS             complement(33876..34586)
                     /locus_tag="IXR05_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAQ4258585.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34583..36055)
                     /locus_tag="IXR05_000032"
     CDS             complement(34583..36055)
                     /locus_tag="IXR05_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4258586.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36193..36666
                     /locus_tag="IXR05_000033"
     CDS             36193..36666
                     /locus_tag="IXR05_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4258587.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36819..37370)
                     /locus_tag="IXR05_000034"
     CDS             complement(36819..37370)
                     /locus_tag="IXR05_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4258588.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37475..38005
                     /locus_tag="IXR05_000035"
     CDS             37475..38005
                     /locus_tag="IXR05_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAQ4258589.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38488..38931)
                     /locus_tag="IXR05_000036"
     CDS             complement(38488..38931)
                     /locus_tag="IXR05_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4258590.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38947..40107)
                     /locus_tag="IXR05_000037"
     CDS             complement(38947..40107)
                     /locus_tag="IXR05_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4258591.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKKQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40614..42314
                     /locus_tag="IXR05_000038"
     CDS             40614..42314
                     /locus_tag="IXR05_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258592.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQKKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42416..43249)
                     /locus_tag="IXR05_000039"
     CDS             complement(42416..43249)
                     /locus_tag="IXR05_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAQ4258593.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCQVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43553..45718)
                     /locus_tag="IXR05_000040"
     CDS             complement(43553..45718)
                     /locus_tag="IXR05_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4258594.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45978..48272
                     /locus_tag="IXR05_000041"
     CDS             45978..48272
                     /locus_tag="IXR05_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4258595.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGFPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48265..48930
                     /gene="pgmB"
                     /locus_tag="IXR05_000042"
     CDS             48265..48930
                     /gene="pgmB"
                     /locus_tag="IXR05_000042"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4258596.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKCH
                     DHG"
     gene            48923..49930
                     /locus_tag="IXR05_000043"
     CDS             48923..49930
                     /locus_tag="IXR05_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4258597.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49952..50971
                     /locus_tag="IXR05_000044"
     CDS             49952..50971
                     /locus_tag="IXR05_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4258598.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51252..52619)
                     /gene="nhaC"
                     /locus_tag="IXR05_000045"
     CDS             complement(51252..52619)
                     /gene="nhaC"
                     /locus_tag="IXR05_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4258599.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFVFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52729..54150)
                     /locus_tag="IXR05_000046"
     CDS             complement(52729..54150)
                     /locus_tag="IXR05_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4258600.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54393..56270)
                     /gene="tdc"
                     /locus_tag="IXR05_000047"
     CDS             complement(54393..56270)
                     /gene="tdc"
                     /locus_tag="IXR05_000047"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4258601.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56561..57817)
                     /locus_tag="IXR05_000048"
     CDS             complement(56561..57817)
                     /locus_tag="IXR05_000048"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAQ4258602.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            58397..59698
                     /locus_tag="IXR05_000049"
     CDS             58397..59698
                     /locus_tag="IXR05_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAQ4258603.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59767..60366)
                     /locus_tag="IXR05_000050"
     CDS             complement(59767..60366)
                     /locus_tag="IXR05_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4258604.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            60620..61501
                     /locus_tag="IXR05_000051"
     CDS             60620..61501
                     /locus_tag="IXR05_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258605.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTVVEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            61514..63124
                     /locus_tag="IXR05_000052"
     CDS             61514..63124
                     /locus_tag="IXR05_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAQ4258606.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(63201..63860)
                     /locus_tag="IXR05_000053"
     CDS             complement(63201..63860)
                     /locus_tag="IXR05_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4258607.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(64143..64808)
                     /locus_tag="IXR05_000054"
     CDS             complement(64143..64808)
                     /locus_tag="IXR05_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258608.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(64955..65560)
                     /gene="dhaL"
                     /locus_tag="IXR05_000055"
     CDS             complement(64955..65560)
                     /gene="dhaL"
                     /locus_tag="IXR05_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAQ4258609.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(65588..66571)
                     /gene="dhaK"
                     /locus_tag="IXR05_000056"
     CDS             complement(65588..66571)
                     /gene="dhaK"
                     /locus_tag="IXR05_000056"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAQ4258610.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(66573..66968)
                     /gene="dhaM"
                     /locus_tag="IXR05_000057"
     CDS             complement(66573..66968)
                     /gene="dhaM"
                     /locus_tag="IXR05_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAQ4258611.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            67122..67442
                     /locus_tag="IXR05_000058"
     CDS             67122..67442
                     /locus_tag="IXR05_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAQ4258612.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(67554..68423)
                     /locus_tag="IXR05_000059"
     CDS             complement(67554..68423)
                     /locus_tag="IXR05_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4258613.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(68519..69793)
                     /locus_tag="IXR05_000060"
     CDS             complement(68519..69793)
                     /locus_tag="IXR05_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003745485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4258614.1"
                     /translation="MLRYLFVYYVFFLVSYPILGGFVWFIGVWCYVFLYKHKQKEWVD
                     VPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGSTDQTPEILARL
                     MKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDALIRYVNYFIRP
                     GARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLYAYSGANTMYR
                     KEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTLKMLYRQRKRW
                     AKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVLFAGLIGHYVY
                     QGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFAPLYMLLFWIV
                     NAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(69819..70328)
                     /locus_tag="IXR05_000061"
     CDS             complement(69819..70328)
                     /locus_tag="IXR05_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258615.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(70503..72638)
                     /locus_tag="IXR05_000062"
     CDS             complement(70503..72638)
                     /locus_tag="IXR05_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4258616.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(72721..74376)
                     /locus_tag="IXR05_000063"
     CDS             complement(72721..74376)
                     /locus_tag="IXR05_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4258617.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(74378..74692)
                     /locus_tag="IXR05_000064"
     CDS             complement(74378..74692)
                     /locus_tag="IXR05_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4258618.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            74862..75122
                     /locus_tag="IXR05_000065"
     CDS             74862..75122
                     /locus_tag="IXR05_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAQ4258619.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            75136..75450
                     /locus_tag="IXR05_000066"
     CDS             75136..75450
                     /locus_tag="IXR05_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAQ4258620.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(76180..76734)
                     /locus_tag="IXR05_000067"
     CDS             complement(76180..76734)
                     /locus_tag="IXR05_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAQ4258621.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(76860..78788)
                     /locus_tag="IXR05_000068"
     CDS             complement(76860..78788)
                     /locus_tag="IXR05_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAQ4258622.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(79094..79810)
                     /locus_tag="IXR05_000069"
     CDS             complement(79094..79810)
                     /locus_tag="IXR05_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4258623.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(79811..81634)
                     /gene="glpO"
                     /locus_tag="IXR05_000070"
     CDS             complement(79811..81634)
                     /gene="glpO"
                     /locus_tag="IXR05_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAQ4258624.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(81648..83144)
                     /gene="glpK"
                     /locus_tag="IXR05_000071"
     CDS             complement(81648..83144)
                     /gene="glpK"
                     /locus_tag="IXR05_000071"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAQ4258625.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(83280..84740)
                     /locus_tag="IXR05_000072"
     CDS             complement(83280..84740)
                     /locus_tag="IXR05_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4258626.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(84730..86025)
                     /locus_tag="IXR05_000073"
     CDS             complement(84730..86025)
                     /locus_tag="IXR05_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4258627.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(86357..87034)
                     /locus_tag="IXR05_000074"
     CDS             complement(86357..87034)
                     /locus_tag="IXR05_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAQ4258628.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(87064..88155)
                     /locus_tag="IXR05_000075"
     CDS             complement(87064..88155)
                     /locus_tag="IXR05_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAQ4258629.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(88256..88690)
                     /locus_tag="IXR05_000076"
     CDS             complement(88256..88690)
                     /locus_tag="IXR05_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4258630.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(89274..90731)
                     /gene="ascB"
                     /locus_tag="IXR05_000077"
     CDS             complement(89274..90731)
                     /gene="ascB"
                     /locus_tag="IXR05_000077"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4258631.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(90728..92623)
                     /locus_tag="IXR05_000078"
     CDS             complement(90728..92623)
                     /locus_tag="IXR05_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4258632.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(92681..94456)
                     /locus_tag="IXR05_000079"
     CDS             complement(92681..94456)
                     /locus_tag="IXR05_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4258633.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(94506..96002)
                     /locus_tag="IXR05_000080"
     CDS             complement(94506..96002)
                     /locus_tag="IXR05_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4258634.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(96196..97818)
                     /locus_tag="IXR05_000081"
     CDS             complement(96196..97818)
                     /locus_tag="IXR05_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4258635.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(98267..99580)
                     /locus_tag="IXR05_000082"
     CDS             complement(98267..99580)
                     /locus_tag="IXR05_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4258636.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGIAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(99825..100049)
                     /locus_tag="IXR05_000083"
     CDS             complement(99825..100049)
                     /locus_tag="IXR05_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258637.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(100069..100437)
                     /locus_tag="IXR05_000084"
     CDS             complement(100069..100437)
                     /locus_tag="IXR05_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4258638.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(100635..101345)
                     /locus_tag="IXR05_000085"
     CDS             complement(100635..101345)
                     /locus_tag="IXR05_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258639.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(101363..101860)
                     /locus_tag="IXR05_000086"
     CDS             complement(101363..101860)
                     /locus_tag="IXR05_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4258640.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(101897..102349)
                     /locus_tag="IXR05_000087"
     CDS             complement(101897..102349)
                     /locus_tag="IXR05_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4258641.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(102484..103089)
                     /locus_tag="IXR05_000088"
     CDS             complement(102484..103089)
                     /locus_tag="IXR05_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4258642.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(103539..104159)
                     /locus_tag="IXR05_000089"
     CDS             complement(103539..104159)
                     /locus_tag="IXR05_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4258643.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLCQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(104161..105030)
                     /locus_tag="IXR05_000090"
     CDS             complement(104161..105030)
                     /locus_tag="IXR05_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAQ4258644.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(105053..105460)
                     /locus_tag="IXR05_000091"
     CDS             complement(105053..105460)
                     /locus_tag="IXR05_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4258645.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(105479..106768)
                     /locus_tag="IXR05_000092"
     CDS             complement(105479..106768)
                     /locus_tag="IXR05_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4258646.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(106795..107097)
                     /locus_tag="IXR05_000093"
     CDS             complement(106795..107097)
                     /locus_tag="IXR05_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4258647.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(107122..109215)
                     /locus_tag="IXR05_000094"
     CDS             complement(107122..109215)
                     /locus_tag="IXR05_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4258648.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKVFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(109704..110468)
                     /locus_tag="IXR05_000095"
     CDS             complement(109704..110468)
                     /locus_tag="IXR05_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAQ4258649.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(110579..111448)
                     /gene="mdcB"
                     /locus_tag="IXR05_000096"
     CDS             complement(110579..111448)
                     /gene="mdcB"
                     /locus_tag="IXR05_000096"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAQ4258650.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(111473..112549)
                     /locus_tag="IXR05_000097"
     CDS             complement(111473..112549)
                     /locus_tag="IXR05_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAQ4258651.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(112573..113166)
                     /locus_tag="IXR05_000098"
     CDS             complement(112573..113166)
                     /locus_tag="IXR05_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAQ4258652.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(113170..114846)
                     /gene="mdcD"
                     /locus_tag="IXR05_000099"
     CDS             complement(113170..114846)
                     /gene="mdcD"
                     /locus_tag="IXR05_000099"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAQ4258653.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(114836..115135)
                     /locus_tag="IXR05_000100"
     CDS             complement(114836..115135)
                     /locus_tag="IXR05_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAQ4258654.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(115237..116883)
                     /gene="mdcA"
                     /locus_tag="IXR05_000101"
     CDS             complement(115237..116883)
                     /gene="mdcA"
                     /locus_tag="IXR05_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAQ4258655.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(116890..117801)
                     /locus_tag="IXR05_000102"
     CDS             complement(116890..117801)
                     /locus_tag="IXR05_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4258656.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            117921..118778
                     /locus_tag="IXR05_000103"
     CDS             117921..118778
                     /locus_tag="IXR05_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4258657.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(118965..119327)
                     /locus_tag="IXR05_000104"
     CDS             complement(118965..119327)
                     /locus_tag="IXR05_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258658.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            119673..121112
                     /locus_tag="IXR05_000105"
     CDS             119673..121112
                     /locus_tag="IXR05_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4258659.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(121119..123671)
                     /locus_tag="IXR05_000106"
     CDS             complement(121119..123671)
                     /locus_tag="IXR05_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAQ4258660.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMAFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(123785..125116)
                     /locus_tag="IXR05_000107"
     CDS             complement(123785..125116)
                     /locus_tag="IXR05_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4258661.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(125082..126560)
                     /locus_tag="IXR05_000108"
     CDS             complement(125082..126560)
                     /locus_tag="IXR05_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4258662.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITLLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(126865..128700)
                     /gene="tdc"
                     /locus_tag="IXR05_000109"
     CDS             complement(126865..128700)
                     /gene="tdc"
                     /locus_tag="IXR05_000109"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4258663.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        37748 a        26969 c        22548 g        41711 t
ORIGIN      
        1 ttttttgcct atcagtgcaa aagcatttcc tgtgcaattt cacgtccatc cattgtatct
       61 ggataaaatg ttggccaatt ctccatttct ttcagcaata cttcttgact ttcatttcct
      121 gcatataaat gaaaatgttc ggagtcagcc ggtgcaatcg tgtgatcact gaattgaata
      181 tatctaaaag cgccactttc cttatcttct gcttcgaata gataccttac gccacggttt
      241 cctgcctcgt aggtcaagat ttctttccct acataacgat aatttgaacg tttcgttgtt
      301 ccatccttaa acgtaaatgc catctctttc tcactgatct tgattgaagc aatatctgtt
      361 tgatagccct tcgtataata ttctttatat tcttgtgctg tcttatcctg attcaatttt
      421 tctttatatt caaaaacagg atcaaaagtc ccatcttcta catacgtatc tactgtttgc
      481 caagttcctg cccaatctga aagagagcga tcttgtacat cctcgtcttc aaaataaccg
      541 ttgtagacgc tcttttcttt tttgggggtc aaagtatctt ctagcgggtt ttctgtctct
      601 gtcgtttttt tcaacgcttc gaggtttgct tccatgatag aaagatagtt ttctccattt
      661 tctatttgtt cattcgtcaa tccttccaaa ggattcaata cttctaaaga tacacctgct
      721 tcgtttgcta acgttctggc aatactatct ttggcgtttt cttcaaaata aatatagttg
      781 attccatgtt ctttaacaaa gtgtttcagt tcagcaattc tcgccgcaga cggttcttca
      841 ctagaagaaa gaccagcaat cgatacttga ttcaatccat attctaacgc tagatagttg
      901 aatgcagcat gttgcgtgac aaaagatctt tgttttgctt gcttaaaggt ttcttgataa
      961 agctgatgga gtgcttgaag tttctcggta taggctgctg cattttttgt ccatacttcc
     1021 tgtttttctg ggtaagcttc aatcagctga tcacgtatgt ttgctacctg cttgattgct
     1081 aaacttggag ctagccatac atgtgggtct agctcatgtg tatggccttc ttccccgtgt
     1141 tcatggtcat gatcatgtcc ttcttcactt cccggaagta aaagcatacc ttctgtcgct
     1201 tttatcgtat ggacattgcc ttcttgtaat gttttttgga ttgcggggac ccatgtttcc
     1261 atgttttcat cattataaac aaagatatct gtatcttgga tctttgccat gtctttagca
     1321 gaaggttcat aatcgtggga atcagtccct gctggaatca ataactctac ttctccttca
     1381 tccccgacga ttgcttttgt aaaatcatac atgggataaa aggtcgtcat cacgctcaat
     1441 ttttctttac tgtcctcggc tttcccactt gccccgcaag cagttaacat acctgctaaa
     1501 accagcatgg ccaatatacc tatcaatcgt ttcatttatg acactcctct tctcatcttc
     1561 tttcatttga atgttccgat tcgcttttcg caaaccgtaa tagttacgtt ttagcaacag
     1621 gatttaattt atcatatggt taaaagaact gtcaagcgtt ttcttatttt aattgatgag
     1681 aaagtttata tgaatgattg acgatatttt tgcaatcaac ctctatcatt ttccttttat
     1741 acccgctttt gtctataatg aagttataga taaaggagga aaaagagtga aaaaagaaac
     1801 agatacaacg aatcgtttga tccgcttttt aggaggaaaa acctcttact atgttttagg
     1861 aatagttatc ttacttgcgc tgatcattta ttttttccat cagatctcgt ttatattcaa
     1921 gcctgtcgga atcattatcg ctactatctt gcccccatta ttgtttgcac tgatcttgta
     1981 ttatcttttg gaaccagtca tcaaacgttt gagcaagcac ctttcgagga acttgtcagt
     2041 cattatcgtt tatgtgatta ttttattttt attggggctt ggaagcatat ggcttattcc
     2101 ttttcttgaa gaacaggcaa agacattgat cagtagtttg ccagatttgt ttcaagattt
     2161 tcaagagagt ctccgacaat ttttggagaa aacacctttt gccgattcat ttaatcaatt
     2221 ttttgcttct attgacgacg tgacgtctga tatagctgga tttattggaa attattggga
     2281 aagtggcgca caacggatca gcaacatttt ttcaactgtt acagctattt ttattacttt
     2341 atttactggt ccaattgtcg cttttttcct tttgagagat cctcaaaaat tttatcagtc
     2401 agttttagcg attgtcccac cagcatttcg tacagatttt aaaaatttga caaagattgc
     2461 taatcaacaa ttgggttcat ttctaaaggg gcaaatcatt gcttcattta tccttggagc
     2521 agtctactgg gtttgtttct tactgatcgg attagaattt gctagtgttt tagctatttc
     2581 tgctgggttg ttatgtatca ttccatatat tgggccgttt atcgccttct ttccaggttt
     2641 gatcattgca ttccaagact ctacttttat ggctgtcaaa tttgtcattg tctggtttgc
     2701 cgtacaactt ctccacggtg acttggtgat tcctcgagta atgggtgatc gtttacagat
     2761 ccatccgatt acgatcttaa tcgttttact tgtcatgggt gatctaatgg gaattgtggg
     2821 cgttattttt ggtattccta tctatacgtt agtcaaatta ctcgttactt ttattttccg
     2881 taaattcaaa caacgctaca ataaatttta tggcgataaa ggagagtatg aaaactcttc
     2941 attttctgaa gaagattatt ttaaataaaa cacaaaacgt cgatcttacg agaatagctc
     3001 gtaggaacga cgttttgtgt ttttgtttta atttttcagc aaagcaattg cctggtatgg
     3061 ttttagctcc agactttgat gaagaacagt atcggaataa ttatcgataa gaatattggc
     3121 ttctgtgaat ccttctggga tggcgatcct tgtatcttta tcatagaaat ttgttaatac
     3181 aagcagctgc tgtccttcaa attggcgaag aaagccataa acttccggat gatttgcttc
     3241 ataagcatga taatctcctt gtgcaacgat tggatatgtt tttctcagcc gaatcaattt
     3301 cttgtaatag gacaaaatag aatcttcaga agatagttct ttttctacat taatctcttc
     3361 tagcttgcct ccaactttta accaaggttt ccctgtagta aatcctgctt gttctgtgtc
     3421 tgaccattgc atgggtgttc gagagttatc gcgagatttt gctttgatcc gacgaaacgc
     3481 ttctttttct gtgaatcctt gttcaaggag taacttataa gcattcaaac tttctacgtc
     3541 aatatagtcg gaaatcgatg aatagtctgg gtcgatcatg ccgatttctt ctcccatata
     3601 aatatagggc gtcccacggt tcaaatggat catggttgct agcatctctg ctccttgttt
     3661 tcgatactga tcgataacta caaatcgatt gagcgcacgt ggctgatcat gattattaaa
     3721 aaatagagca ttccagccgt taccctcact catattttct ccccatgtat gaaatagtcg
     3781 ctttaattct gcaaaatcaa atggaggagt agaccattta ttcccatttt cataatcgac
     3841 tttcaaatga tggaaattaa agaccattga taattcttct ctactaggtt ctgtatacaa
     3901 gatacaattt tcgatcgtcg tagagctcat ttcaccgact gtgatgatag tggaatccgt
     3961 cccaaacgtt gcttggttca attcttttag atacgtatgg gtgattggtt tgtccgtata
     4021 ttcaggtttg ccatcatttt ctttattatt tttcaattgt tcgtctttac cgataacatt
     4081 gataacatcg aaacggaatc cttttacccc tttttccatc caaaaacgaa caactttgaa
     4141 tagttcctct cttactgctt ggttccgcca gttcaagtca gcttgtgtcc gatcatataa
     4201 gtgcaaataa tatttccccg tatctccaaa tggcgaccaa gcacttccac caaattttga
     4261 tacccaatcc gttggctctt ctcttaaaat gaagaagtcc tgataatgct ggtcccctgc
     4321 tagtgctttt ttgaaccatt catgttctgt cgaaacgtga ttcagcacca tatcgagcat
     4381 gatttctatc cggtatttct ttgcttcggc tattagctgt tcgaattcct ccatcgtacc
     4441 aaagatagga tcgatggctg tgtaatcaga gatatcataa ccgttgtctt tttgagggct
     4501 tggataaata gggtttagcc aaatcatgtc gatgcctaga tcattcagat acgggagttt
     4561 ttctttgatt ccttttaaat ctccaattcc atcaccatta ctgtctttgt aagatttggg
     4621 atagatttgg taaatgactt tgtctttaaa tgtcatggat atttacctcc attcaactga
     4681 tttattacct accacagctt atatatacaa gttatcattt attattataa ctgaacagaa
     4741 agcgtttgta aaatttatct ttatacattc taagaggtct gttgcccaat aaaaaacaag
     4801 agatcagaca tgtatttgtc tatcctcttg tttaaaatag caaaatattc ttgtttcttc
     4861 tataaatggt gttcaaaagc ttttatctac ggcaatcagt cttctcaaat gtaaaacatg
     4921 aggagctaat tttatttgag tattcttttt gctcgatgca ggacggcttt tttacaacct
     4981 ctgattcatg gtgttcaatt agcagctgac cctcgttatt agctcaaaac gctgatttca
     5041 caacctctgt ttttattcat tcgatttcaa cgcatcaatc atatcgatat gctttaattt
     5101 gaaatgggta acaatcatca caataaccgt aaatacgata gttaatcctg ctgataagac
     5161 ataagcccac catgtgatca ctaatggaaa gatgacattc tccatagacg cttgttgcaa
     5221 gatgaagtca gtcaatatat atcctacacc aaatcctccg atgattccta aaagagtaaa
     5281 gatgatattt tctcgaacaa tgtacatcgt gacttcttta tcaaaaaatc caaggacttt
     5341 tattgtagat aattcgcgta cacgctcgga aatattgata ttagttagat tatacaagac
     5401 gataaaagcc agcagtcctg ataatacgac aaagattaag acaaccgagt ctaagttcgc
     5461 cattgattct tcttgcgttt cgatttgttt ggacatgaaa gacgtatttg tcacagcgtc
     5521 tgtggcaagc agtttctcgg aaagcatttc ttcttctttt gttgtcatct tatctgtacg
     5581 cagcaaaaat gcattatcca tcatcgattg atcagtaact gaagcataat attcagggga
     5641 catataaata aagctaccta gatagttttt cacgatttct tttacttcga ctttccattc
     5701 tttttgatct tcatcataaa gcgaaatatg atctcctgta gataagtcaa atagttctgc
     5761 tactttttgc gtaatagcga ttcctgtttt aggcaaggag cgtgggttct cttcaagatc
     5821 agttaaatgg ataaaacgat ccaaatcagc tgttttactt ggtacgatca ctgtcagact
     5881 ttgcgaagca tgtccttttt ttctcaattc tacggtttga gtatgaatag ctaggatctc
     5941 atttactttt tcttgcttct gcagcatatc cgctgctttt tgacgactat cttccgtgga
     6001 tgaatccaat gtaacgattg cttgatagtc aatgatcggt ccaaattgtt tggctgaaac
     6061 agaacttaga gaatctttca atcccacgcc tgcaaccatc agcccggcac atccagcaat
     6121 tccgataatc gccataagca ttcttgactt atatcggaag agatttcggt aactgatttt
     6181 ttgattaaag ctaaggcgtg accacagcgg agtgatgtat tcaagaaaaa tgcgtttccc
     6241 tggcttcggt gctttcggtt gaagcaatgc agcaggccgt tctcttaaat ctttgaataa
     6301 aacgatcatt gcagcgccaa atgcggcaat gaagaatgcg gcagctgctt gtaaaatcgg
     6361 cggccagtca taaaaaataa gcgcactccc aatatcatac cgctcgttag acagctcaaa
     6421 aatgatcctt ggcaaaagat tcgttcctaa tatcgttcct aaaacaatac ctatccctga
     6481 ggctagactt gcatagattg catatttttt tgcgatttca actttcgtat aacctaacgc
     6541 ctttaatgtc ccgatttccc tgcggttttc ttctaccata cgtgtcattg tcgtaaaggt
     6601 gatcaatgcg gcaataaaga aaaagaaaac aggaaaaaca ttggcaatcg cagcgatacg
     6661 atcagacaga tcaccaaatt cttgaaaacc gacattttct gaacgttcat tgtataggta
     6721 tgatggttta gttaaatttt caattttttc tgcatttcga ttcaattctt cctctgcaga
     6781 ggccagttca cgttctttct caactaattg cctttcttgt tcagcaagtt gagcttcttg
     6841 ttgaggtaat gtttgaacag cgattgttcg ttgcgcttca ggaagctgct ggatagttgc
     6901 tgactgttgc gctaactgtt ttttagcatc ttctaaccgt gttcttgctt gcgttgtttg
     6961 tgctttgcca tccgctattt tttgctgtgc cggttctaat tcttcgttgg ccgatttttt
     7021 cagctcttct aagcgttctt cgggtcgatc ttgtaaatac ttttctgcct tttcttgatt
     7081 ttgctccatt ttatctttgt aagctttgct gtacgtattc aaattcttta cgtttgtaaa
     7141 atcaagatat aagacagaat aaatatctgt tttaaaaacg gattcaggta aatagacaaa
     7201 ataatcgacg ctaccatttc cgacgttcgc gtatcctctc tccaaattgt tgatgaacaa
     7261 tggagaacgg acaaagcccg tgatggtata ctctttttct ttcaattcat ctgaatcaat
     7321 ctgataaata tcaccgattt tatacccttc atcttccgct ttttcatcca atacaagctg
     7381 gtttggtttt tccgggagtt ttccatcagt taattgtagc ttgttctgct tgttattttt
     7441 gttataagaa aatatttgaa tcacttcgtt tttgccagta ttggaataat agatctgttt
     7501 tcctgtttct acttttgcat ctgggatctt ttctgcttga gcaatatctt tttgtgtcaa
     7561 gccaccagta gaaacgattt gcaaatcaga aagtcctgct gtaccaacat agtgatccat
     7621 cgttttttgc atgacaggtc cagcagtttt gacacctaca aataaaagtg ttcctagcat
     7681 gacaataagg atgattgcaa tgaatcgtcc tttagattgc cgaatttcgc gaaaacctgc
     7741 tttaagatat gttcttgttt tcataaaatc cccctaccat acaatctcat caatggatga
     7801 aggatgatca tttaattcaa cagaccttac tttagcatca ttaatgtgaa tgactctatc
     7861 agcgatgggc gctaaagcag aattatgtgt aatgatcaaa acggtattgc cgtgttgtct
     7921 gctagcgttt tgcaataatt tcaatacttg cttgcccgtt tcaaaatcca gcgcgcctgt
     7981 cggttcatca cataaaagaa gtttgggatt tttagctagt gcacgagcaa ttgaaaccct
     8041 ctgctgttcg cctcctgata attgggacgg aaagttattc aatcgatgag ctaggcccac
     8101 ttgcctcaat acctctacag gatcaagcgc atcaggagaa acttccgttg ccaattccac
     8161 attttctttt gctgttagat taggaacgag attgtagaat tggaaaacga accctacatc
     8221 tgttcgtcgg taagcagtaa gctgtttatc tgaaaattgc gcaatatctg tgtcatcaat
     8281 aatgatctga ccttcatcag gtgtatccat cccacctaaa atattaagaa tcgttgactt
     8341 tcctgctcca cttggaccaa gtataatcac taattcgcct ttttcaattg aaaaagaaat
     8401 atcgtcattt gctgtaatgg tcgtttctcc cattttgtat cgtttgtatt cattttttac
     8461 ttcgacatac ttcactctga ttcctccatt ttcacgatat ttctcgctat atctatgcat
     8521 cgaatgcgtt ttctcacact tatttatttt accactgaat ttctctagac taaagaaagg
     8581 aatcctttaa tttagttgac aaataaacga tttatgattt acttacataa aaaacattgt
     8641 tatttgaaag aaggaacatc atgaatgatt taaaggaaaa tatgattttt gatttatcaa
     8701 aaactgcttt tgtcgcgatc gacatgcaaa aagagatcgt aaataacggt acactctctc
     8761 cacacactgc agcatctatt ctgacaaaca atgatttgtt agtaagaaca ttgaaacgta
     8821 ccgctgcctt gaaagtttta gtgaacgtag acatctccac tttcccttat ttgagtcaac
     8881 aaactgatat gggtggaatg actgcttctg tacctccaga attcactgat ttacttttga
     8941 aggattcttt gaaagataca gataatatgt tgactatcaa aaaatacaat ccaagtgctt
     9001 tttttggtac ttctcttgat cttcaacttc gccggcgtgg aatcgaaact atcattttaa
     9061 gcggtgtagc gacaacaaac ggtgtatatg ctactgcatt agatgccttt caacacgggt
     9121 accatatcgt gcttgctgaa gatgcttgca gtgatcgtga caaagaatcc catcaattgt
     9181 tcataaaaaa gatatttccg aaaactgcac gagtacgctc aacgaaacaa ataatcgaag
     9241 ctatccaaca aagcaaataa gtactggcac acgtgatttt catttacttc tttttgattt
     9301 catgggaaaa taaccacagg atttagatag gagtatgaac atggtgaaaa aaaagatcac
     9361 aatcaaagaa gtcgctaaac tttccggcgt ttcaatcaca actgtctcct tgatattaaa
     9421 tggaaatacg gagaaattca gtccgaaaac tgttcagaaa gttttagctg ccaaagaaga
     9481 attaggctat cagcctgact attttgctag acaaatgatt accaaggaaa cgaaaacaat
     9541 tggtgtactc gttcctgata tcacgaatcc attcttcagt acactgatgc gaggaattga
     9601 ggatatcttg tataagcaga atttcgtcac gatattatgt aatgctgatt ctgatcatca
     9661 aaaagaaatc gaatatctag ccgagctcac acgtcgaggt gtggatggat tcattatcgc
     9721 gacttctgct gtctctacag atgcaatcaa cgaaaatttg aaaaaacaag gccggccctt
     9781 cattgttttg gatcagaaaa aatctgaagg atttagtgat gccgtacgaa cagacgattt
     9841 tcgcggtggt tacctagcgg gcatgcactt gcttagtcta ggacatcaaa cgatcgccct
     9901 tgtctatcct gaaaatccac cggaaaatgt ccacgctcgg attgaggggt ttaaatctgc
     9961 tcttgatgtt taccaaatcc ctcacgacca actgatcctc ttacctacac agttctcaaa
    10021 acaaggtggc taccagatca cagcagaact tcttgattct gctgcaactg gtgtgtttgc
    10081 tttaaatgat gaattagctt ttggattata tcgcggatta gaggaagctg gaaaaagcat
    10141 ccctgaagac tacagcatta ttggctatga taatatagat atgtgcgagt atatcaagcc
    10201 gaaactgaca acgatcgcac aaccaatctt cgaattggga caaacatctg ccaagttatt
    10261 gttagatcgg atccaattcc cagaaaaaga atgggaagaa aaaagattac ctgtacgatt
    10321 agaaaaaaga ttttcaactg cacccttgaa atagctttca aggtgtgcta tatttttatc
    10381 gaactattaa aacgttttac taaaacgttt taaaaaataa ttttcccatc aaaataaatg
    10441 agatagttgg aggtttgtaa aatgaacacg gttacagtaa ttggaagtat taatatggac
    10501 actacccttc gtttaaccaa catgcccaag ccaggcgaaa cgatgcatgc gcatgagatt
    10561 tttcacgctg gcggaggtaa aggtgccaac caagcagtgg cagccaaacg ttcaggcgca
    10621 cggacatctt ttattggagg cgttggggct gacagcgaag gacaacagtt attagatcta
    10681 ctgacaaaag aaaacatcga tacatctggg atagctgaaa tccaaggcgc cacaaccgga
    10741 caagcaatga ttatggtaga cgcagcagga gaaaatagta tcttgatcca tgcaggggca
    10801 aataatgctt tccatgaaca agaagtccta aaaaacaagc aactgattac aaacagtgac
    10861 tttattattg ctcagtttga aagtagctta gatgcgacga tcctagcttt ttctattgca
    10921 aaagacgcag gaaaaacaac gatcctgaat cctgcaccag ctcgtgaaac gattcctact
    10981 gaactacttg aaaagacaga tatcattata ccaaatgaaa cagaaacaga aatcattaca
    11041 ggaatcagag tgacagatca taacagtttg gtcgcagcag ccgaaaaact ccatgaatta
    11101 ggtattggaa cagtaatcat tacactaggc agtgccggcg ctttctatca tacagaaaaa
    11161 gaacacggta tcgtccctgc ttttaaagtg gatgccgttg acacaacagc cgcaggtgat
    11221 acatttattg gcgcattaag cagcacactt cagccagacc ttagtaactt gaaagaagcg
    11281 atcctttatg gaaatctagc ctcttctgtt gctgtgcagt cttatggtgc gcaaccttct
    11341 atcccttacc gcgaagcttt agaacaatca gcagtctaaa attaacaatg agaggaagaa
    11401 acaaacatga aaaaaggaaa agtaatcaat tcagatattt cacgagtaat cgcacaaatg
    11461 gggcactttg ataaattaag tatcggggat gcaggcatgc ctgtcccctt tggtactgaa
    11521 aaaatagatt tggctgtctc aaacggtctt ccaagttttt tatctgtttt agaaaacgtt
    11581 ttagaagaac ttgaggtaca atcgattgaa ttggcggaag aaataaagac aatgaacccg
    11641 gaaatattgg aaaaaatcaa attattgtta ccagatacac cgattagctt tatcccacat
    11701 gaagaaatga aaaaagagtt gaataactgt catgcattta ttcgtacagg cgaaatgaca
    11761 ccttacgcca atattatatt agtgagtgga gtggtcttct aatggaaacg acaatgaatc
    11821 ctgaacagat ggtactgtcc gagcagattc atatgctgat tgaacagttg ggaggaaaag
    11881 acaatattga ttctgtcctt ccatgtgcga ctcggcttcg tatcaaattg aaaaaacagc
    11941 cagtagccaa tgcagaaaaa ttaaaacagc aaatcccttc cattaagtat ttcattttac
    12001 tcgatagata tgcagaaata atcatggatc agggattggc tcctgcttac aaggaattga
    12061 cgcgtcaaat cgatcattca gctccgaaag aaaagctaaa tccgatcgaa aaactatttg
    12121 gtttgatatc ggaaatcttt acgccgatca ttccgctgtt tgccggttct ggtatattaa
    12181 aaggtctggt tgttttagcg actacgattg gctggcttag tgaaacaagc ggaacttatc
    12241 atattttgtc tgctgcgtcg aatgccgtct tttattttct gccaatcttt cttgcttttt
    12301 ctgctgccaa aacgtttaaa gtgaatggat atattgcggc tgtcattgct gcagcactga
    12361 ttgaaccgaa tctgacctct ttactttcag acagtggcaa agcagctact gattttctgg
    12421 ggattcctgt agtactgatg cagtatacgt ctactgtcat gccggcgatt ttaggtattt
    12481 tcttttattc ttttgttgaa aaattcctca aaaaatatat tcgcgaaaat atgcaattag
    12541 tatttgtacc tttactttca ttagttatca cggttccttt gacgttaatg gtattcgggc
    12601 ctgcgggtgt ttaccttggc gaaggtttag ctgccgcaat tacttggatg atggatatta
    12661 acggaccgat cagtggcgca atcatcgctg gtggttggaa tattttggta atatttggta
    12721 tccaatgggc tgtaaaccct gtcatgatca gtaatatctc tgcttatggg ttcgaccgaa
    12781 tcgttccgtt gacaggagca gccaattttg gaatggctgg tgcagcttta ggtgtatttc
    12841 tgcgaagtaa acgttcaaaa acccgttcga tctccggttc tgcttttgct tcgattttac
    12901 ttgcgggagt gaccgaacca actgtttacg gaattgcgat cccattgaaa aaaccatttg
    12961 ttgctgcttg cattggtgca gctgctggtg gagctgtaat gggatttgcc caagtgaaag
    13021 cgatcgcttt tgtatttggt agtctgacca cattgcctgc attcatttcc ggtacttttt
    13081 tctggtactt agcaggactg gctgttagtc tagtcgtagc aatgatcact actctcgtta
    13141 gcgggtttga tgaagaccta atgtcttatg aatagttaat gaaaaagact gaagtatgag
    13201 atgtttatca catatttcag tctttttctt tttaggatca ttatttttat aaatttttgt
    13261 gatactttcc aaactttggt ataatttaca tatgcataac catttttatc cccacttgtt
    13321 tatccccaaa caaaggtggt ctatgcaata aaatgaacgt caaagaaaaa cgaatgaatg
    13381 ctcgttgctt atttacaaat tgttttattt agaatacaca gacagattta tgaaaagaaa
    13441 aagcttttcg acacgattat ctgttccaaa aaatgtctaa tgaatgctga ataagacaga
    13501 aaatcaatga aaggaaaagg actagtttat tatgaaaaat aaaaaaacga tacgtttgct
    13561 agctgctact tggctgattg ctccgtctgt tttgtcgacc aataccgtat ttgccgtaga
    13621 taatcaaata gctgatcaaa cagtcacaac agatacgact acatccagct cagctactag
    13681 tgaaacaacg gattctttta cagaagaccc aactggaaca actaactcaa caacaggatc
    13741 gaccgagcca actgaaattg atccggctga tccatcagaa aatgaaaagc cagccgagac
    13801 atattccctt acaattgctc cttctttgat tggtaagatc caactgactg cttcgacagc
    13861 ggattcccct gaacagcaac ctttggatat tacggaaagt ggaacggtag aaggtttatt
    13921 agcggaaacg aaggtaactt acactattac gccagctgaa ggtgaacaaa ttgcttcagt
    13981 cgctgttaat ggtgccaaag aagtaaatta tgatgcaaag acctttacag taggtacgaa
    14041 caatttatct attactgcag aatttaaagc tggaccggat acttcaacag agaaaccaac
    14101 tgatcctagt gaagaagtcc ctagtacacc agatccggaa acgccaaaca aaccagatgt
    14161 gggtaataac aacaataata atggttcaaa taattcaaac aataataaca ataattcgaa
    14221 cagcgggaat tcttcgaatc aaacaaaccc atctggatcg aataacaatg gaaatactca
    14281 gagagaacca aaccatccaa acaatggttc atcgaatggc ggaacgaaca atgcttcatc
    14341 tcgtccaaat acagcaaatc aaagcggtat agagaatcca tcttctgctt cttctgattt
    14401 tgttgtaaaa tcaccaattg atgctgtatt gcctacaaat acaacgaatg tccaacaagc
    14461 aatcgttcga gaagcattca agcatcttgg aaaaccatat gtatggggag caaaaggtcc
    14521 aaatactttt gactgttctg gtttgactta ttacgtatat atgaaagcaa ccggtcatta
    14581 tatcggtggc tggacaggcg aacagcaata tgcaggtacg cagattccag taagtcaggc
    14641 ccaacctggc gatctcgtct tctggggacc ttcttccggt gttactcacc atgtaggtat
    14701 ctatattggg aacggacaat ttatccatgc gcctcaacca ggagataaag ttcgagtaac
    14761 ttctatttca gatttcacgc ctgattttgc tgtccgagta aacttagcag gtttacctgc
    14821 tgcttcaggt tcgctgacag gcggctcatc tattttagat ggattagatg gctcgttcca
    14881 tttcagtcaa aaccaaacaa ctgatcagtt cttgaaaaag attgcagatg atgcacagga
    14941 aatcgggcaa aaagaaggaa tctacgcatc agtcatgatg gctcaagcta tccttgaaag
    15001 tggatctgga aacagcttat tatcaagcga accaaatcat aacctttttg gtatcaaagg
    15061 atcatataaa ggaagcagcg tgaccttcaa tacacttgaa caagatagtt ccggacaaag
    15121 ctaccaaatc cgcgcacaat tccgtaaata tccttcttac aaggaaagtt tggaagacta
    15181 tgccgacttg atcaaaaatg gactgactgg caatcctgat ttctacaaac caacttggaa
    15241 gtcggaaaca aaagactaca aagaagcaac caaatatttg gaaggacgtt atgctacaga
    15301 tcgccaatat tcacaaaaat tgaacgcgat catcgaagcg tacgacctga caaaatatga
    15361 tgaaccgaaa aaagaagcag caacaactga agaagcaaac gctgaaatcc tcaatatgtc
    15421 taagcgattc gatgtgccaa tcaaatggac aacagatggc gtgccaatca caggattaga
    15481 attttcaacg ataaaacgcg tcaacaacgc ttcttccatc ttccgtgtcg cttcaatctg
    15541 ggatttgtgg aacaatttta cggcaagaca gataccagaa acaactactc gtacagttaa
    15601 agctgcaact gttcctgtac taaccttgtt aagtttagac aaatcattct ggcttgatct
    15661 gcctttaaag aaatagaata aattaaaaag gggatgtgac actgtcacac tcccttttta
    15721 atttattcta tttctttata tttattttgt attccgttac aaactcgcgt acttggttag
    15781 gttccagagt gacatctcca aaactttcaa gtcgctccgc tcctggcagt tcttgagtct
    15841 caaatgtgat accgccatga tttactaatt tattcccgcg catttccggt ccatcttctc
    15901 caaaatttgc tgtaaaaatc acgattcctg aagcatctgt ttttacttgg atcgatactt
    15961 tttcatctgg gcttgtcaat tccgcagcat ttagtaaacc agattgtttt ttcaacaaaa
    16021 atggatgatc gatgccgccc actatcattg attggcgaaa atcactggca aagacctcac
    16081 ctaatttttt aggacgttgg aagtcaaatg ctgtgccact tactgaaact acttctcctg
    16141 taggcgttgt atctttattg agcgtagcaa ataatcggct attcaaccaa agtatatgtt
    16201 cgtcgattga ctgtgctgga tcaccggtta aattgaaata gacatgattt gtaggattga
    16261 atactgtttt gcggtcactg atcccttgga ccgtcactcg ccatgtatca tcgttcgtca
    16321 gcgtataccg tacttctaca tctaaagttc caggaaatcc gtttcccata tctgggctag
    16381 tctgatagaa aatgaccgat gcttcgtttt caccattgat gactgtataa tgccactgct
    16441 tggcttcaaa gctaggtgca ccaccatgta aacaatgacc agtgtccggg tctgttttta
    16501 cttcgaacgt ttcatcatct aatttgaatg tgccattcgt aatccgtcca gccatacgtc
    16561 cgattgaagc accgatataa gggtcttttt ctagatattc ttttgcttca tcaaaaccta
    16621 agatcaactc tcgtttttca ttatcgatta ttgtttgaaa atgaacaacc cgtgccccaa
    16681 gatcactgac agacaaagat gtcccatttt gattcgtgat cgtaatcaag tgatagtttt
    16741 cgccaaaatt ttgttcattg atttccatgt tccttgcacc ctcttttctt tcatttgcac
    16801 tgattccagt atacatggaa accgttttct taacagctta ttccgtgagt aacgagaaaa
    16861 aatttactat attctaataa aagaccgtga aaaaaaggtt gtgacaaaaa tattgtcaca
    16921 acctcttttt ccgaacaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca
    16981 aacgaaaaat atgaggagct atttttgctt ggctgttctt attacttgat gcaggacagc
    17041 tttttcacaa tctctttttc aatacgattc cagtatataa ccatgtcgtc agtacatagt
    17101 agatgaaata caatacgaag aagatcgtaa acggaaccca aatatctttg tatggatttt
    17161 gcatgaatag accaaacatt tgtaatccga ataagacatg gactacacct aagattcctg
    17221 gtgctaagaa taacacgcct acttctctac ggatcgattg tttaagcaac ccgcgtcgtg
    17281 ttcctatctt ttcaagcatt tcataacgag caatgtcact cttgcttcct gacaagatct
    17341 tgaacatcaa acagctagca agcatggtca agaaagctaa acctaggaag aatcccataa
    17401 attcaaaacc agagaataga ccattataca cttcatacat ttcatatttc tggttgctgt
    17461 actctacttt ttgcaaagat ggattgttca ttttattttg agcaacaagt gtttcgattg
    17521 gtttcaggtt tgcttggaag tcttttacct gaactagctg taaagtggat tgtggcaagt
    17581 tcagttgatc aaattctgat tgactgacta ccttgatttc tttttcttgc tgttccggca
    17641 attcatagct tcgaagttcc tcttgtacag tcagttcatt cattttttta gcaggaactt
    17701 tttctttcgt gatcttcggc ggtgttccat cttcatgttt tatcatgatc aatggttgag
    17761 ccgcaaattc acttgcatta tagtaaatcg ttcccgcatc ttctttttga gtataagaag
    17821 cagaaagtgt tggtgaaagt tctttgattt tttgctgatc ttctgcccga ggattattca
    17881 tcactagatc atatccagaa ttgttttctg tcaagtctgc aatttcattt ttaaaaccta
    17941 atcctaccgt caaagcgccc agtgccaagg caaacagcat agcgaccatt gagagcattt
    18001 gtgtatattc acgaatacga aagtttaact gtgacaatgt gaaattgttc aattttttca
    18061 atgaaatctg ttctgatttc tttagtaatg ataaaaagaa aatgatcaca gaatggaaaa
    18121 tgaaataagt tcctaatatg atcgtaacta aggctacccc tataccaaag acttgatagg
    18181 tccccacgtg tttcatcata tagtaaccgc agcctagaaa agcaattccc agtactactt
    18241 caaggaaaaa caagaattta tgctgcttga ttcttgttgg tgtctgatcc gcacgaatca
    18301 atgctaaaat cggttttttg acaatcgaaa aagcattgac aacagcagct aataaaaaca
    18361 aaacagcaaa aaacaaaaca gtgatcaaca acccgtgaat actaaaaggt gtaaaatgcg
    18421 aaatattgag atctaactga tccactaata atcggtggac gatacttgtc aatcctacac
    18481 cgacagctga acccactaaa gtagctgcga tccctactaa gaatgtttca gaaaaaatca
    18541 tctgtgcgat ttttctgcct tttgctccca gcatcataaa cattgcatag tctttttgcc
    18601 gcatcgtcat caaaaaggaa tttgcatata aaatataaac gaatgtgatg atccctagta
    18661 aaacagaacc gaatcggaaa atgataactg tagccgcaac gatcgtatta cttttcaaaa
    18721 aagcttcgtt gcttgccatt gattcaaaca tgtaaaaaat agcagatgcc ataactaatc
    18781 ctgagaataa caccaagtag tctcttaaac ggctcttgat cccagtaagt gataatttcc
    18841 aaagcatagt caatctcccc ctactgttcc aagtttccaa gaatagatag tatttctcga
    18901 tagaaggaat cacggctttg atctccacgt ttcacttctt gatggatacc gccatccttg
    18961 atgaataaaa tacgttggca ataacttgca gaaaacggat catgcgtcac aagaagaatc
    19021 gatacatgat cttttgtatt caattcgtcc atcgtatcta aaagatcccg ggcacttttg
    19081 gaatccagcg cacctgtagg ctcatcccct aatagaatcg ttggttgtgt gatcaatgca
    19141 cgtgcggcgg cgacccgttg tttttgtcca ccggaaatct cagaaggata gctttccaaa
    19201 atatgagaga tggataaacg ttctgcaatt ttttggacac gttgcttgat ttcttttggt
    19261 ctgacgcctt gtaaagaaag aggaacagcg atattttctt gtgctgtcaa gctttctaat
    19321 aaattgaaat cttggaaaat aaagccaatc tcattcgcac gaaaatctgc tagttgattt
    19381 ccttttaatg tggtcacatc tttttgattg attcggatat gcccatctgt tggtttatct
    19441 aatgtggata aaatattcaa aagtgtcgac ttaccagaac cagaagcgcc catgatccca
    19501 ataaattcgc ctttttctac atcgaagctg atgccgctta atgcttgcgt ctttttctca
    19561 ttgttttttc cgtatacttt tgttacattc tgtacttcga ctattttgtt catttctttc
    19621 cctacccttt aattagtttt tccagtgctg ttttcggcac gtcttttttt tcgacttctt
    19681 catacgaagt gacaccttta tttttgttcc aggtgatttt taaatatgct cctttacgaa
    19741 gcggtcgagt caattgtccc ttgaagtcca gttctttttc cttaccctct ttcgtatagc
    19801 caggcaggat atatctatag ttgactgttt cttgtccaga gtctgatttt gaaactgttt
    19861 ttgtaccatc tgtcgtaatt tgtacatagt attcttctcc acccataact acgtaatctg
    19921 cgattttcac ccctgcaagt accacaacga tgaaaacaag tagaccgatc agaagttttt
    19981 tcactttttc cccttctctc ttactttata tactgattat agaaaaaagc gaacaattct
    20041 gccttcgaat caactatcat tcttctttca attttgtcat tttctttaaa acaactaaaa
    20101 aaagagttca agacaataat ccgtcctaaa ctccttcttc ctatcttaca aaaagtatgt
    20161 cacttacggt ctttcatgtc gcctgtattg ataacaggtt gcgttccttt gtctgtaatg
    20221 attgagacaa gtaaattatt gatcaattgg actttccgat catcggtgaa attgatttct
    20281 tgtccatctt cgatttgctc taaggccatt tgagtgattg tgacagctcc ttcaacaatg
    20341 gtttgtcgag cagacaaaat ggcttttgct tgttgacgtt ggagcatggc actagcgatt
    20401 tctgttgcat aggctaaatg gttcaagcgt gtttcgatta cttcgacacc tgctactgct
    20461 aaacgctctt gcagctcttt ttgcaactcg tcagacactg ccgtcgtgtt tcctcgaagc
    20521 gtcaaatcat tctcattgaa tgtatcatac gggtattggc tagcgatatg ccgaatggct
    20581 gtctcacttt ggatttctac aaaatcttga taatacgcta catcgaataa tgcctttgct
    20641 gtatcaacga ctttaaagac tactactgct gagatttcga tggggtttcc atccaaatca
    20701 ttgactttta aaacagaact attgaaattc cgaactttca acgaaacagt cattttttgt
    20761 gccaaaggta tcgtaaggaa aaagccattt tctcgaatcg tacctaaata ttgtccaaaa
    20821 aacaaaatta cttttgcttg attaggactg actacagttg ccgaacttaa caacaataac
    20881 gtgatcaacc aaagaaaaat acttaaaaaa agtgcccaaa ctttcgcttg ccacatacct
    20941 aaatagaaga aaaacaatcc aactaaagct aatacgacca atccgacaat ccctgcataa
    21001 ccattgatat aaaatgctct tttttctctc atgctacttc ctgcgctcct ttatccttca
    21061 ataaatatct aatgttactt ttttaatttt ttttcgaata cgcgccatta caccttctag
    21121 ttctaactct ttgtcttcag tgatgtacca accccttgcc tgtgtccctc cggctgcctg
    21181 cggtaaataa tccaattttg ttcgaaccca gtgcttttct tctgtaaaat agtcttctac
    21241 caagacctct agatccatcc ctgctgaaag aggcaaatct tcccgaacag atttaaagat
    21301 aaatcgttcc ttcttcccat catacttcaa tattcctgta tcgataatcg gtaaagaata
    21361 ataatccagc tctttcttca ccgtcaataa atgtttgaaa acttcatggt acacttgctc
    21421 taattggcga ccttctgaat tgttcgggta attaaccatc actttttctt tgtctggatc
    21481 atagaaggtt tggcttagtt gagtgatata agtatgtaat ctttccattt ctgtttttaa
    21541 cttttctctt tgaccttctt ctaccttcat atactctttc accctgtttt ctttttagat
    21601 attttctttc ttattttact atagttatgt gcgttaagcg atgaaaaaca gcaaagattg
    21661 gaaggatctt tgctgttttt tcttaaaata tccagttgag tacaggatca atctgtttca
    21721 ttgtcctctt gatccgtcgt aatattgatc gatgtgtctt tagcagtgat ctttagcttt
    21781 ttctgtcctt gttctaacaa agtatttgtt attggctggt agtctttttc aatataagat
    21841 tcaccagacg tttggatagt atagccactg ttttccatct catgcaaaga taaattgcca
    21901 ccgtttagga tgacttttcc ttctttgctg atcaaactgt cttctagatg gaagttgctg
    21961 ttttcacctg tgacgatcaa gttatccaca ttggcctcat ctaatcgaag tgagcctaat
    22021 tcatctttcg cagttattgt tcctcctgta aattcattga acgataccca gccatcatgt
    22081 gtcttagtat tcactttttt gattgatact tcgttgatat caattgcact attattccct
    22141 tcgattgtca attcagataa ttcatgatct gcagggacaa caatagtgat ttgtgcactt
    22201 gtgtcttcta aactaatgat tgcacctgtt gattttttga ctgcattcac agtcaacacg
    22261 ccatttttct cctttatttc tggcttttct gtcttatcat aagtcgtttt tatctcaaaa
    22321 tccaatccgc gtatgaccga aactgtttga ttttctgcat ggatgacgat tttgtttgca
    22381 tccttgattt tttttgtctc agtaaccata tcgatcaacc gaggaccatt atcccaagtc
    22441 agactctttt gagcgcctaa tgtataagtt gcacctgcta ggaggccacc agtaagcatc
    22501 agaccaatac cggtaatcaa aaaatgtttc aatctcaatt tatgtgtcct ccttcaaacg
    22561 cccgctgaat gcagatctct ttttgtaata aaacgtcgtc ccatccattt aacaaagttc
    22621 atcatgacat aaaaaagccc ttttgttcct ttcagcaaca gtggcgaaat aaatactgcg
    22681 cttcctgtgg cgaacagacc gacaccgata aagaataatc cactcagaat cgattgtcca
    22741 aacacactga ttcctgagat gatcatgaat aggccaacac ctaagatact gatacataaa
    22801 acatagatac taaaaatgag cgctagtaaa gcaaccaata gtcccccaat aaccaatata
    22861 aaccccagtg ctagtggaat gaggacagga gaagcaaata aaccgataat gattaaccaa
    22921 atcaggcgaa tttgtctttt tggatttttc actaactcgt tttctgcttg ttcttcttct
    22981 gaaaagtaac tgatttttaa ttttaaggca aactgctttg gtgtaccata ttcatcaatg
    23041 atctgatcta atgtttttcc agaatctaaa aaatattcct cataatactg gatcaaatca
    23101 aaacgatcgt cttcaggaat ttcttgaaga tgatccacaa cttcattcaa atattcattc
    23161 atttgtgctc tcctccaata accggtctaa agaatctcga aaaacaatcc attcatcaat
    23221 aatttcttct aaatgacgac ttcccattgg tgtcaacgag taatatcgac ggtttctgcc
    23281 ttcaaaaggt tcatcatagg tctcaagata tccttctttt ttcaatcttc tcaaaaccgg
    23341 atatagtgta gattcactga cagagagact ttcttgtacg atttttgtta aggcataccc
    23401 atacatatct tccttgctta atgctgctag cacagtacca tcaagaagaa cagttggaat
    23461 ctggatgtgc attacgtcac cttctattct caagtgtaat attttatttc aatctatatt
    23521 atacaacata taatatagtt tcaaaatcag tttgtcaaat acaaaaaaac tgactaaaag
    23581 atttgatcct ttttagtcag caaaaaatgg cttctctttg atttttatta taacagtggc
    23641 ataatccaat ttgtccacat ccagctcagt ggcatgataa cgatcattgc aggtatcatg
    23701 tcagctactg ggaacatttt cacgttgatc attctaaaac cggtagcgac catcaagaat
    23761 ccgccgcaag ctttaaaatc taagatcatg tctggtgtag tcaatggata aataaatttt
    23821 gccaataaga acaaaatata aaaaataatg aattggggaa ttgctatcac agaaacgaca
    23881 taccctaaat tacacgcaaa aatagctgct gtgaaaaaat caaggacaga tttagaaatc
    23941 aaaatcgtac tgtctcctgt catcccagaa tctaaacttc catagatccc cgtaccactt
    24001 gcacaaaata gaacaatgac cgtcactaat gtgctgataa attcatcgtg ggtcatacca
    24061 agcttttcac tagggaagat tttagaaata ggtacttgca tcagcgcagc ccccttattt
    24121 atcccattac ctaaatgaac aatcagacca atcgctgttc ctatcactaa agcaaaaata
    24181 acagccggca tatttttcat cggcgcaatg gaatagattc ccatccccat cgaacacaca
    24241 ccaaaaacca tcgtcagctg tgctttaaaa tgttcactta atttatttcc tactaatccg
    24301 ccaattagtc cgccaagcaa aacggaacct acattgatca aaactccagt tggcatcaaa
    24361 aaactcctct ctttttctac gaagcgaaaa aaatcagaaa aatttctgta attattgctt
    24421 tcgctgcaag aaagattgta acagacagag aagattacac caattcattt tttgtgttaa
    24481 agtattcttt attggaataa gtaggaggaa tatgatggat atccataaat tcgaagtttt
    24541 tcttgattta gccgaaacaa tgaatttcac caaaactgct gatcgacaat tcaccaccca
    24601 aggaaatatt tctaaacaga ttctttcgtt agaaacagaa ttagacgtca aattattcga
    24661 acgcgcccat agaaaaatcg aattgaccga agctggaagc ttattgctcc catatgtaaa
    24721 aaatgtcgta gaacaatacc atgctatgca agaagtgctt gaaacctata cgaaagacaa
    24781 caatctttca ttaaatatct taacgatacc gacaatgatc aattataaag gtttttccaa
    24841 aatcaccgag tttttgaaac gccatcctga atttacagtc cagttgaaag aagtggaaag
    24901 tgtcgaatta acttacaatg acgccaatga acatagtgac acgatccact ttgctagaaa
    24961 tttccaggcc ccaccaagtt cgattgagtg gttgcctact gaaacagacg attttgtagc
    25021 agttctacct aaaaatcatc ctttagctag taaaaagaaa ttggatctaa gcgaactgaa
    25081 aaaggagaac tttttgctcc ttggccccac tacgaacttg tatcaacctg tactagatct
    25141 gtgtcgcgaa gctggatttg aaccaaaaat ctcttataaa ggagcaagaa tcgacttgat
    25201 catcaatatg attgcaaatg acatggggat tgctattgtt atggaaaaaa cagtcaagaa
    25261 tctattaaaa gaaaatactg tgattctccc tatttctcca acaacagaga gttatcttgc
    25321 atttactcgt aaagtcggtg agcattcttt ggcttcagat acattttggg agtatttaaa
    25381 tcaagaagaa aactaagccc tacattttct gtccatctat ccacccaaaa aaagagagcg
    25441 acgcatgact ttcgctctct ttcttgcatc atgtccttgt ttcaatgaca cctctaacat
    25501 ttctcgtagt tcaataagaa agcagcgatt tttatgccaa aagaaccgta agaacatttc
    25561 cctaatcaca aaaaaacgac taaaaacccc taaaaacctt caatagaatt tttaggggtt
    25621 ttattctttt tcctattgtt tacttaaccg tatcattgct gtcgttccta ctccttcgat
    25681 actgctataa tcaatacgtc catcatgcag ttctagaatt tttttaacca gtgaaagtcc
    25741 tagcccattc ccagaaattt gacgacttgt atctccttga taaaattttt caaacattcg
    25801 atctctggtc tcttcattca ttcctacacc tgaatcggtc acttccagtc caatctctgt
    25861 ggctgtctca aatagtttga tatgaatctg tccattgatt tgattgtact ttatggcgtt
    25921 atccatgata ttcagccaca cttggtacaa aaactcttca ttgcctgtgt aatttactgc
    25981 agcaagttcg atatccaatt ctagctgttc tttctcccat ttaggctgca aaaaaacgat
    26041 tacttctctg atttgttcat ctaatcgata ctctttcttt tccagttgga tacgctggtt
    26101 ttccagtttg ttcaatttta agatgttctc tgttaattgt gaaagctgcg tgatactttc
    26161 gataatccga tataaaaata tttggcgttc ttcgtcagag agatttgggg cttgtaacaa
    26221 ttgaacatat ccttggattg ttgctagtgg tgttttgaat tcatgggata cactggacac
    26281 aaagtcattc ctcagtgtct cgatactatt gagttcttgg accataacgt tgaaatcttt
    26341 atacagttgc tgtacttctg ctactttctg ctgttcatcc attcgaatcg aaaaatctcc
    26401 cgttgctacc agactcatat ttgtccctag cgcactgatt ggatgcagga tacgccgccc
    26461 aacaaaaatc gatattcctg tacccacgac catactgaac cccgcaaaga cgaataacgg
    26521 gtataacgtt ggttttccag ccgattcagc aggcgagata gaatgtcgag acaataagaa
    26581 aataaaaccg agaaaacaca gcagtgtcac taagatcgaa atgaagacaa tactagcaaa
    26641 atagatccat aattgtgaaa atagcttttt tttcatcttt aaataaccgc cttatagcct
    26701 agtccccgta ctgtgatgat ttgaaaatct tccgtctttt caaaacgggt ccttaaacgt
    26761 ttgatatgta catcgatcgt tcgttcttct gtattcgtat ctaatcccca aatatcatcc
    26821 atcaactgtt ggcgagtgaa gatcttgttg ggataagaca gtaatttata cagaagcaga
    26881 aattcttttt gaggcagaat caacgaatgc tgatcttgta acactgtata agcatctagc
    26941 tctaattttg tttgtccgat tatcaagcta ctgctgtaat tgatctttga acgtcgaagc
    27001 aatgcttcca cacgtaggat catctcattg acatcgatgg gttttgtcat ataatcatct
    27061 gctcctaatt tgaacccgcg tttcttatcc tcaaaatcgg cctttgccgt aatcattaga
    27121 acaggtgtgt caaatctggt gctacgtaat gagtctagca agtcatagcc atccattttc
    27181 ggcatcatga tatctgtaat gattaattct atacgtgtcg cttctagttt tttcagcgca
    27241 tcctctccat tcaatgcggt gatgactgaa aagcccgctc gttccaacac agaacggtaa
    27301 agcaactgta attgcggatc atcttctact actaaaatac gattcattga tctccctctg
    27361 ttttttgaaa aatttctaga ttttttcttg tagttcatct tcagttaaca tttatttcgt
    27421 atactacgat cattgttctg atatacttat tagtataccg aatatttcaa tacgggagaa
    27481 gggtgattat gcttcaatta aaagatataa aaaaatatta taaagtcggc gaaaccacca
    27541 ccaaagcatt ggatggtgtg tctgtcgctt tcagacaaaa agaattcgta gcgattttag
    27601 gtcctagtgg ttctggtaaa acgactatgc tgaatgtgat tggtggacta gataattatg
    27661 attccggtga tatggtaatc aacggaaagt ctactaaaga ctttaaggac agtgactggg
    27721 atgcctaccg aaacaactct atcggtttca tttttcaaag ttacaacttg attggtcatc
    27781 taggcattat tgaaaacgtt gaacttggga tgacattaag tggtgtttct aaagacgaaa
    27841 aacgaaaacg ggcagaagat gcattgcacc gagtcggctt gacagatcat atgcataaaa
    27901 agccaaatca gttatctggt ggacaaatgc agcgagtggc catcgctcga gcactagcca
    27961 atgacccaga tatccttttg tgcgatgaac caaccggagc gttagataca gaaacaagta
    28021 tccagatcat ggaattgatc caagagttat cgaaagaaaa attagtgatc atggtcacac
    28081 ataatcctga actggcccat caatacgcag atcggatcat tgaattttct gatggtaaga
    28141 tcttaacaga ttcccatcct cacatcgaac gaccaaaaga tgatcaattt aacttacgca
    28201 gaacaaagat gagtttttgg acagcgttaa agctttcctt caacaatatc cgaacaaaaa
    28261 aaggacgtac tttcttgacc tcctttgctt ccagtattgg gatcatcgga atcgcgatcg
    28321 ttctgtccct ttcttctgga ttccaaaaac aaatcgataa cacgcaagct gaaacgatgg
    28381 cgaaatttcc gattactatt tctaaggtaa cgactaacca gactcgtgac gatgccggat
    28441 tgggtgcaag caaagcggat tatccagaca gcaaaacgat tactgcaaaa gtcagcgaag
    28501 aagataaagc acagcacacg aataagattg atcaaacata cgtcgattac gtaacagaca
    28561 tcgatcctaa cttaagtaat aatatcggat ttacccgtac tacaggaatc aatcttttac
    28621 gtgatgtaaa tggcaaagta cagcctgtca gcttctcgaa tcaaaatcct gatacggaat
    28681 ctctttcttt atctagtacg atgtcagcaa tgacaggtgt gggagtgtca agtttcccta
    28741 cacagcttga cactagcaaa gaaaactttt taaaagacaa ttattcttta cttgccggaa
    28801 gttatccagc ctcagcaaca gatgtcgtgc tgatcgtaga cggcaataat aatactaata
    28861 tcaacgcatt gaagaatctt ggatttgatg tgaaagaaga cgaaaaactt gattttgatg
    28921 atatcgttgg tacaacattc aaattagtaa acaacaatac ttactataca aaacttccaa
    28981 ctgggaattt tatccctaat acagattatg atgcgatgta tcagaatgct tctgatgaat
    29041 tgaagatctc ggggatccta cgcgtgaaat cttcttctac aatgaatctc ttatctccag
    29101 gaatcgctta tagcgatcaa ttaacgactc aaatcgtcaa cgaaaacaaa gaatcagaaa
    29161 tcgtcaaagc tcaaagagac agtggtgtaa atgtcttaac tactgaaaaa gttgacgaaa
    29221 atgccaaaca aacattgctt agttatttag gtggagacag cttgccttca agtatcatga
    29281 tttatccgaa caattttgaa gacaaagaaa agatcttgga ttatctagat gattacaata
    29341 aaggcaaatc agatgaagat aaaatcattt atactgattt agctggaacg atgactgaac
    29401 tgactggcgg attgatggat gctatcactt atgtccttat tgcttttgca gggatctctt
    29461 tagtaacaag tatgatcatg atcagtatca ttacttatac atctgtgatt gaacggacaa
    29521 aagaaatcgg tgtactaaaa gctttaggtg cacgtaaaaa agacatcact cgcgtatttg
    29581 acgcagaaac gtgtatttta ggtatttctt ctgggatatt aggtgtgttt attgcatggc
    29641 tagctacgtt ccctatcaat agcatcttat acaacatgac ggatctaaaa aatgttgctc
    29701 aactaaatcc tgtccatgcg attattctag tgatcgtctc tactatattg acgatgcttg
    29761 gcggtcatct tcctgcacga atggcagcga aaaaagacgc cgctatcgct ttgcgtgcag
    29821 aataaggttg tgacaaccac atttagattt gagtcataag agcgctgaaa tagtagaaaa
    29881 cagcaagaaa cgaggaagta atatgttcct tgtttcgcgc tgtttttttt aattattttt
    29941 tataattctg gtatactttt ctttcctttg taccacaact cttctggcgt atacctgtct
    30001 tttccattta tgaatactgt tccatctgct tcaatcgtta cttcagtccc aatccacata
    30061 ttacgagaaa gtgcgagaag attttttctt tttcctcttc ctttttttcc aaattgcaag
    30121 gcatcggtta tctcttctgt ccaatgagat ttcacgtatt ttacttctcc gttttcaaat
    30181 gtaactttca aaatattcgc tatattttcc acttttactg ctttaggaaa tgactccttc
    30241 atttttttca ctttccttcc tccaacacta agtatgcgct ttcttttagt gataagtata
    30301 tcatagttta ttctattatc aaaaaaacgc atccattcca ttgtagaata ctttaccgaa
    30361 caagttgaat tgttttcctc tttttcacct tttactatag ataggtaaag acaactaagg
    30421 aggaatctct catgacagat caaccgtatg atttaagaaa agtcatcgaa gaactaaaaa
    30481 cacttccagg tcaatatcac gaaacagata ttgaaatcga tcctgaagca gaattatctg
    30541 gtgtttaccg ttatatcggt gctggcggta cagtaaaacg tccgactcaa gaaggaccag
    30601 ctatgacttt caacaatatc aaaggtttcc ccggcacacg tgtgaacatc ggaacaatgg
    30661 ctagtcgtaa acgtgtaggt gaaattttgc accatgatta tcgaacactt ggtcgtttct
    30721 tgaaagacgc tgtagaaaat ccaatcaaac ctgtgaaagt agacaaagca gacgctccag
    30781 cacaagaagt cgttcatcta gctaccgatg cagacttcga tattcgcaac attttgcctg
    30841 cacctacaaa tactcctgaa gatgctggtc catacatcac aatgggtgta gtcttaggat
    30901 cagatccaga aaaaacaatg agcgatgtaa cgatccatcg tatggttcta gaagataaag
    30961 atacgatcgg tatgtacatc atgcctggcg gacgccacat tggtcacttc caaaaacaat
    31021 tcgaagcctt gaataaacca atgcctatca ctatcaatat tggtttagat ccagcaattg
    31081 ccattggcac gactttcgaa ccacctacca ctccacttgg ctacaatgaa ctatggtgtg
    31141 caggagcttt gcgtaacgaa cctattcaaa tcgttgatgg tatagcagtc gatgaagtgg
    31201 gtattgctcg tgctgaattc atcattgaag cagaaatcat gccaaatgaa acaatgcaag
    31261 aagatatcaa cacgaactca ggaaaagcaa tgccagaatt tcctggctat actggggatg
    31321 ctaatccagc tgtacaagta gtgaaagtca aagcagttac tcaccgaaaa gacaatccaa
    31381 tcatgcaaac aacgattggt cccagtgaag aacacgtatc tatggccggt attcctacag
    31441 aagcaagtat tcttgccttg gtcgataaag ctattccagg aaaagtagta aatgtctaca
    31501 atcctcctgc aggtggtggt aaattgatga ccatcatgca aatccgtaaa gaaaacgaag
    31561 cggatgaagg tattcagcgt caagcagcta ttcttgcttt atcagccttc aaagaattga
    31621 agacagtcat tttagtcgat gaagatgttg atattttcga catgaacgat gtagtttgga
    31681 ctttcaacac tcgtttccaa ggagataaag atatcatcgt gatcccagga atgaggaacc
    31741 atccattgga cccatcagaa ttaccagaat ataatcctgg ctctattcgt ttccgtggga
    31801 tgagtgcaaa aactatcttt gacggtacag ttcctttcga tatgaaagaa cattttgtac
    31861 gtgcaaaatt ccaagaagta gaagattggg aaaaatattt gaaataatga atgatctgca
    31921 actgttttga catcataaaa aggagtgcgg aaaatggaac aattggcaca acggaagaaa
    31981 aaaatcgtga ttggtgtaag tggcgcttca ggcaccattt atgccatcaa cctagtgaag
    32041 aaactaaaag aatatccgat gatagaaaca cacggaatca tcagtccatg ggcaaaacag
    32101 aacttaaagc tggaatccga cttatcacta actgaattcg aaagcctgtt tgattaccat
    32161 tattcaaaca aagatttagg tgctgctgtc gccagcggat catttttgac cgatggaatg
    32221 atcatcgtac cggcaagtat gaaaacagtc gcaggtatct ctgttggttt aggcgacaac
    32281 ctgattgcac gtgctgctga tgtaacaatg aaggagcaac gaaagttagt cattgttcct
    32341 cgtgaaacgc cattaaatgc cattcacttg gaaaacttga ctaaattagc acgactaggt
    32401 gtgcaaatca taccaccaat tcctgctttt tataatcagc ctcaaacgat ccaagatctt
    32461 gttaatcacc atacaatgaa acttttggat caatttggaa ttgtaaatga gcattcaaaa
    32521 cgttggcagg gtgattaata tggaaaaaga aacgatagtt gaagtaacca aactaggttt
    32581 cacgatccaa gctgctgtta aagtaatcgg taaagactta ttgatcactt taacaggcgg
    32641 agatacacca catatcggaa cagtcactac attttctcgt gatacagaga tgcaaactgt
    32701 acgtttccct agccacgatg gtcggttcca taaagacgat gtcttagccg aaaaaatagc
    32761 tgtgatcatc aaaactgccg ttccgggaag ttgtacgatc acttccggta tccatgttga
    32821 ccatatctcc aatgcacaaa tcaacgcctc ttttccgatg tcagaagagt taggttacaa
    32881 gattttagat tggttggaaa aaatagattt ccatatcaaa gaaccagttt attataaaga
    32941 tggtgaaaaa acattatgaa agaagaggtt gtgaaatcag cgttatgacc tgagtatgag
    33001 agaaaaaaat ggaaaaatag cttctcatat tttgccgttt ttgagctaat accgagggac
    33061 agctgattga acgccgttta tcaagaggtt gtgataaagc cgcttcgttt cgagtagtaa
    33121 gaaaaatttt gtaaacatgg gtttccacat ttttgcataa atttgactta ctaccgagaa
    33181 actggctttt gaacaccgtt tatcaagagg ttgtgacacg tcttttgtca caacctcttt
    33241 tatttttgct tcactgtaac tgctacaata tcaccgattt cttttccgat gtttttacga
    33301 atatcttttc gtagtccaag gatgtagcag actgaaccat ctggattttt cacgcccata
    33361 ttcacgatac tgccttcata cggcatattg tcaaaagttg cttggacttt aactcttcca
    33421 gcaccgaatt cttttcttat atcatacgga aaaataatat atgccccgcc cttgtcgact
    33481 tcggaagcat agatttttga ttcaaaagaa taaatttccc tcattttatt tctcctattt
    33541 tttacatcta gtatagcata gcaaaaaaaa gaaggaactg tgacaaaagt cttgtcgcag
    33601 ttcctttttt cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatagt
    33661 caacaaacat gagaagctgt tttttgaaat tgctccttgt gactcagagt taaacggcag
    33721 gctcacaacc tcttccttaa acggtgttca aaagcttgca tctacggcac taagcccaat
    33781 cagatgaaaa atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca
    33841 gctttttcac aacctcctac atggtgttca aaatattatt cgccttttgc ttctttcact
    33901 aattttgcga atgcttgttg ttggaattca gcagctaagg ctttcgtacg ttgttcttgc
    33961 tctgctttgc tcatttttgg attttcagtc attgctttta ccataccgtc ttgaacataa
    34021 gcttttgctt cactttccat cgtactttgc tgtttcttca ctaattcagc taacttggct
    34081 gcttggtccg tacttaattc tacccatgtc tctgggattt tgaatgtatt cactcggctg
    34141 tcatattcgt gattgttatc agcaatattg aaccagaatt tatacatgtc gtttttgtat
    34201 tcccaataag tagttttcgt cactttttca gcatcgccgt ctgtcttttc tactttattt
    34261 gtttcgttat ccgtaccagt tgcttttggt ttttcttgtt tttcatttgt tcggtaaaga
    34321 tacacttttt cttttccatt ccctaaagct ttatacaaaa gcatatctgc tccttgggaa
    34381 tcagcactgg aaacaatttt ttctgttttt gtttccgtta ctttttccat tccaaagtga
    34441 ttggacaaat tagcgacgat caaacttagt gaagcgacga agattagtcc gaaaatcaaa
    34501 gataaaaagg tttgccatgt ttttttagcg aacacgttcg ttaaagcaaa agcaagcaag
    34561 ctgacaatca aaactccaat aatcatgcat tatcccccgc tttcattaga acaggttctt
    34621 ttttcttcaa taaaaaggca ataataaagc caagaatccc aaagatgatc gctacgataa
    34681 acgcggcatg gtaacctgac agtgtggcat tgattgcctg atctttataa gctaatggcg
    34741 tattatccaa tacagatttg cttgggatat ttgcttttgt cacattcgtc aacacactga
    34801 tcaaaatagc tgtaccaatc gagcttgcga tttgacggaa tgtattattt accgctgtcc
    34861 catgactgat caagttattt ggcaatgcat tcataccaga agtcgttacc ggcatcatga
    34921 ccatggagat cccaaacata cggatcgcat aaaggatcac gatatataaa actggagtcg
    34981 tttttgtcaa gaaagcaaat ggtgcagttg ccgctgtcaa aatgaacatc cctgtgatgg
    35041 ctaaacgttt cgcgccgtat ttatcgaaaa tcgcacccgt cacaggcatc atagccccca
    35101 tgatcaatgc acccggcaac aacatcaagc cagaatggaa tgctgattct ccacgaatat
    35161 tttgaatata caatggtacg accatttctg cccctaccat cgccatattt gttacaccag
    35221 ctaaaacagc tgcaatcgtg aatgtagatg atttgaatac acgaagttcc aagaatggat
    35281 gttccaaatg taattgacgc catgagaaca aggcgatgaa aatcacacca acaactaaga
    35341 aaccaattac tttcaagctt ccccagccgt catctcctac actagaaaat ccgtaaagta
    35401 aactaccgaa tccaatcgtt gataaaatag cggataaaat atcaatgcta ggatttgaca
    35461 atggaataac acttttcatt aggaagaatg ctaaaaccaa gacaagaaca acgattggca
    35521 gtaccatacc aaacaagtca cgccaatggt agttatcaat gatataacca gataatgtag
    35581 ggcctaaagc aggagcaagt ccaataacga tccctgacat ccccattgct gatcctcttt
    35641 tttctggcgg gaaaatagat agcatgatat tttgcaataa tggcatcgat actcccacgc
    35701 cgcaagcttg gatcaagcga ccgattagta atgtactaaa attaggtgct gtaaagcaag
    35761 taatcgttcc gatcaaaaag atcgtcatgg cagaaagata taaatttctt gaactgaatt
    35821 tattgatcag ccatgctgtt attgggatca tgatcccgtt gactagcaag aaaccagtcg
    35881 ttaaccattg cacatcagac gctgaaatat cgaaagcttt catcaatgta ggaaaagctg
    35941 tcgtcaataa ggtctgattc aaaacggtac aaaatgtacc aattaataag acaacaacta
    36001 aaagtgtccg attatatggt tttccgtaaa tatctacggg ttggttgtta ctcatatttc
    36061 tccttctttc tgaatttttt ctgaaactac tagaatactt tagtcctaaa ttcgctattt
    36121 gtcaacctac ttgacacata agttaatacg gatataatta agggaagcaa gaggacaaaa
    36181 ggagtgacaa aaatggttgg ggcttccctt aaacgtttgt tggaaaatga tcaattggtt
    36241 gttggcatca gtgaattaag tgatatcgta ggtgtgtctc cacgtcaatt aaggtattgg
    36301 gaacaaaagg gattcattcg ttcgatcgaa gctgatgcga attgtcctag aaaatatcgt
    36361 ttacctacag tcataaaagt agaactgatc aaaaaatatt tagatgacgg atttactttg
    36421 tcaaaagctg cagaaaaggc agaaatccgc caaaagaaaa tgcaccatgt ccgtaaagtt
    36481 ttttcaaaag caatcaaaga tatcgaattg atcgacgaac gctatacgat tttacaaatc
    36541 ggtaacttca aagaagagaa tgctaagatg tacatcattc atgacaacga gacagacgaa
    36601 ttaacttaca agctccttcc tgtcgatgaa aaagctgact acgaacagtt gttaaaagaa
    36661 ctctaaacgc cactaatctc ctaagtacca agctttttaa taagtagatg ctacataaat
    36721 acttgaaaaa aggcctgttt gaacataaga atatccgaac ggtgatctgc gtttctttca
    36781 tatagaaagg aattctccat cactgttcgg atattttttt atttttttcg gttactttct
    36841 tctaatacat ctgttagcca atttgcatat tctgtttccc gattgatcgc atgcgctaaa
    36901 atcaggtagt gtccgtaatt ttcatgtttt tctttttcag taggaaagat cgtttttttt
    36961 cgctctaata gatgaagtcg tttttcttca tgaaggtcac gctgctgctg aataatttct
    37021 actaatgccg gatcattcac gtctttgacg aaatacaatt tcagaacaaa ttcgtctcga
    37081 ttaaccggta gttcattggt tggtgtatga atccactctg ccaattgttc cttcccttct
    37141 tctgttaatt cataaacttt cttttccaat ttttcacctg tgatctctac ttgatgctga
    37201 atgattcctt gctcttccat ttttgcaagt tcaggataaa tctgactatg ttttgcttgc
    37261 caaaattctc ctatttcatt tttgaacgat tgattcaatt catatcctgt catcttcttc
    37321 ttacttaata accctaacaa aatatatcga agtgtatttt ttcttgccat cagttttccc
    37381 tccttgacaa atctttaaat ccattctatc ataaatgagt aatcgaaaac atgtagttta
    37441 ttacatgttt taatttataa ggagatgctt aaacatgaaa gaatttaaag aattggaaga
    37501 ttttattgga actcacttta tctatacgta tgacaatggt tgggaatatg aatggtatgc
    37561 caaaaatgac catactgttg attaccgtat ccatggcgga atggtcaaag gccgttgggt
    37621 aaaagaccaa gaagctgata tcgttaaatt gacggacggc gtattcaaaa tcacttggac
    37681 agagccaaca gggacagacg tggcattgga ctttatgcca aatgaaaaga aacttcacgg
    37741 aatgatcttt ttccctaaat gggttgaaga acatccagaa atcactgtta ctttccaaaa
    37801 cgaacatatc gcagaaatgg aagcagctcg tgaaaaatat gaaacttatc caaaattact
    37861 tgttcctgaa tttgctacga tcacttatat gggtgatgca ggtatagaca atgaagatgt
    37921 tattagcgaa gaaccatacg atggaatgcc agatgatatc cgtagcggaa aatacttcga
    37981 tgaaaattat aaacgagtaa aataaggttg tgaaagagag gttgtgaaat cagcgttctg
    38041 acctgagtat tagagaaaga aacggaaaaa tagttcctca tgttttgccg ttttttgagc
    38101 taataccgag ggtcagctga ttgaacaccg tttatcaaga ggttgtgaaa tcagcgttat
    38161 gctttgagta ataagaacgc tagttagaaa atagcttttc atattttcta ggctagtggg
    38221 cttattaccg agaagcagcc gtttgaacac cgtttatcaa gaggttgtga aatcagcgtt
    38281 ttgacctgag tattagagaa acaaatggaa aaatagttcc tcatattttg ccgttttttg
    38341 agctaatacc gagggtcagc tgattgaaca ccgtttatca aagattgtaa caactgcata
    38401 ttcacacagt taaattagtg acttcaaaat gaaataatgc tcccagcaaa aaattaggct
    38461 gggagcatta tttcgttatt ctgttcatca aaaatcagcg ttttgattcc atttcatcac
    38521 aagttcctcc tcatttactg cttcatcttt ttgctgtgtt tgaattgtaa aaccttgtga
    38581 aagatagaaa tgaatagctg attgattttt ttgatagact gtcaaagtca gtgttttatt
    38641 ggtttctttt atttttttca ttagttgcgt accgattctt tgttgccggt attccctttt
    38701 cacaaagatt cctgcgataa actgatcaat caccccagca aaaccaataa tttcttgatc
    38761 tatttctgct aagtaaatca ctgcatctgg taaagctttc ctaacagatt ctacttgatt
    38821 ctcccaataa gttgatggaa tgaattcatg agaatccaag ttagcatgca gccaaatcga
    38881 tagaacagat tccagttctt tggcagacaa ttttgttgtt gtgcggatca ttttttctct
    38941 ccttacttat tcattgattt taaaataaaa accatttttt tgaagctctt ttacaagttt
    39001 tcgcccctca aaaaagtata tcttctcttg ttttactttt ctaataccaa aagaaacagc
    39061 aactttagga tcatcagctg aaacgattcg ataagttcca ccaggcaatt gatccagctt
    39121 gactttccca tgatggtcgc tttgtactga aaacggcaca ccatttctag taagtgtttt
    39181 tttcttatgt ttcaaaatga atgaactacc atttaccggt ttccctgacg aatcactaat
    39241 aataaatgaa aaatcaagca cttttttact taatctatac tgatagatta gtcgtccgat
    39301 aaacactaac agtatgacta cagctattat cgttcctgca agaataaacc attgccgcat
    39361 ggttctttcc tgatttcctt ttccttcttc tttttttacc gattcgttat aaggaatccg
    39421 atgtcctgtc actagcaaac gatgcgtgtt gatcatatac ggcgtacatg taagcaaggt
    39481 aactaagtct tctccttctg aaatcgttag aacagacgtg tcatctggca gtaccacttg
    39541 tatattttta acttgataag ccaatttctc ccccaaaaca gtcaaaataa acgtgtctcc
    39601 gttttctaaa cgatctaatt cggtaaataa ccgtcgatta ggtaaaccgc tgtgagcaga
    39661 gatcactgaa tgcgtcgaat ttccaccaag cgggaaagag gttccttgca agacgcctgc
    39721 tccattttca aggatcctac cattgagccg atcataaagt gaaatattta attggatctt
    39781 aggtatattg atacttccga tcagccattc ctctaattgg ctggatgttg tactttcatt
    39841 tctgttcttt tcattgaaag gatcagtacc aggattgaat ccttggtcag ttaatcgttg
    39901 ttttttctcc tccattttct ttcgctgcac ttcaatttca gctgcggtcc gtttttgtac
    39961 ttgttcgata cgtttttgat caataaaact atttaaagaa tccacataaa atggatataa
    40021 agcgatcagt aaccctacga cgatacatat taataaaaac aaacgaaaca aaagtcgacg
    40081 agactgtttt tgcttactct gcttcacatg tgtcctccct tgcaagtttt tttgttcttt
    40141 cttttattat atgggttcag gaaaaaaata gaaaatgaaa gccgatgagg ttgtgaaaaa
    40201 gctgtcctgc atcaagtaat aagtacagcc caaaaaaata gctactcata ttttttgttg
    40261 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa
    40321 aactgcgtta tgctttgagt aataagagcg ctagtcagaa aacagcttct catattttct
    40381 aggctagtga gcttattacc gagaagcagc tgattgaaca ccgtttaccg agaggtcatg
    40441 aaaaagctac tttgtttcga gtattaagaa aaattctgtt tcaaaacaag gagatgcaac
    40501 aaaacttatg tcgcatcctc tctccttaga actttcactt atgtttttct tgtaaaattc
    40561 ataaatattt tcatgaattt tctaatttct tgcctacctc tcgcatagga tatatgatga
    40621 atttatctaa agtttgcaaa ggagttcgac aattgaaaaa atatggccca tttttagcaa
    40681 tttttttcat tgctttggca tttctcatgc ctcatttatt cacacataaa ctaattttgg
    40741 gtgctgatgc cccattccat tacaatcggt tctatgatgc cgcgcaacaa attaaatatg
    40801 gggatttcca ttattttcct tccctttatg gattccagca aagtggcagg atcgtgaatg
    40861 ccgtttacgg cccatttttc gcttatttac aaggattgat cgtgttgctt gcaggtagct
    40921 ggtttcatta tcagattctt tcaaatttca ttctttatct tatttcagga ttttctatgc
    40981 tgattttact gagatatgtc aatgttcgaa attgggtaag tgtaccagta gccgttttat
    41041 tcatgagtac gtattctatt caatactggt ctatcaacca aggattcact agctggggga
    41101 cttgttttta tcctttatgt atgatcccta ttgctgattt cgtccttcat aaaaagttcc
    41161 ctgttatcaa agtcgctgtc tcagtgggac ttatgacaca gatccattta ctgtcttcga
    41221 tcatgttagc tttgatgtat atcccttttt atctttatta cttttttaac cagactgaaa
    41281 aaggaaaagc actgcttcaa ctgattaagt cggtcttgct ttattttgtt ctgacagcaa
    41341 atatttgggc aggattagct attgtttaca gtgggaataa gattcttcct ccctttgtta
    41401 acagagaaat gagtcaaaag gcgatagatc tggatggcag ttattggctc cattacccta
    41461 aggcctttcc tatattgata ttatcaggtt ttttgctttt tattttcttt caacaaaaga
    41521 acaccttatt ccaaaaaatc gtgttgtaca caagtcttgt tttctttttt ctttctacta
    41581 gcttgattcc atggacgaca ttgatcgaaa aaaatgtgcc ttttattagt ttgatccagt
    41641 ttccatttcg atttttcgtg ccatttacgc tattgcttct actttacctt gccctttcac
    41701 tgaaccagtg gtctgaacaa aagtggttcc gtcttttaag tatatttggc attcttattt
    41761 tttcagcaca gacgatccag aacttatacc agcatctgga aaagtgggaa aatgaaacat
    41821 ttgtcagtcg acatacttat ctattcgata cgccggaaga agcaaggaaa acattcttca
    41881 gcaaagatat gtctaccagc ttgttcgttt tccaaaaaac cacacctgac tatctgccaa
    41941 tctataagga gacaaaagac aataaatacg accggtataa cgaagaaata ctagaaaacg
    42001 aaacaacttt tataaaaaca catccaggcg gtcttttgac aatcaagtgg aaaaacactg
    42061 gggacaaaac tgttcatatc cctgttatcg tctacgatcg gactgtgcta cagcaaaatg
    42121 gaaaaacatt gactgattat gaagtaacag atatcgggac cccaatcgtg aagcagaaaa
    42181 aaggaatcaa cgagctcacg cttcattatc aaacgccaat ctatttctat ttcattcttt
    42241 ctcttacttt gattggctgg tttaccttgc tatgtttatt tatttatcat agatacaagc
    42301 ttttacgtgc ttaggcaaaa gggataaata catccgatca aaaaactctc caaacggtat
    42361 aatcgtttgg agagttttat tttaatcagt ttttttatgt tatatgttat attttttatt
    42421 cgttcacatc taattcgatt tccaccccgt agtgatcact gatgattgga ctatcgatcc
    42481 catcaaaaat ccgttgatat tttttaacct gcattccttc agggacgaaa ataaaatcta
    42541 tacgcaattt ttctgtattt tgttcccaac catctatttt cttttccaca gtagctgctt
    42601 ttcctttttc attcgcgaca acatacgaat cttgaagaag aaggcaactt tctcttacag
    42661 tataataacc ttgagagtct actggattat tgaaatcacc taggaaaaaa agtggtacgc
    42721 gagtttccaa aaagtagttt tccaagtttt tccactcaaa ataaaagcca ctttttttat
    42781 ctgtccacca agaaaagtgg cagctcgaga caaaaatgtc ctgatcatct atctttgttt
    42841 tcccaatcaa gatcttgcgt gtctgataat cttctttctt ttgagattgg gagacggtaa
    42901 ggacctgact ttccaatgtt tttttcgtaa gcagtgcatt tccttcttca tatttatcat
    42961 aaccgatgtg gctcatttcc caactccaaa aatactcttt tccgtgttcc tttaaaagct
    43021 gaactaaacg gtaggcaaaa ttatctttac ggataggtac ttgattcttt acctgacaga
    43081 acttcattag cttcgcaggt tctacttctt cagattccag taattggttg atttcttgta
    43141 aagcaatcac ttcataatct tctaacagga tcttatctgc taattcttgc aattttttct
    43201 ctggttctgg ctcaagccag ctatgcgtgt tgagtgtcat gaatttcatt ggttttctcc
    43261 ttgtcttcat ttcgaaacaa aagggttgtg acaaaatttt tgtcacaacc tctccagcaa
    43321 atagtgttct cctgctaact cctcagtaat aagctcaatg gaccaggagc tattttttgt
    43381 ttggctgttt ttatcacttg gtgcagggca gctttttcac gacctctcca ctaaacagta
    43441 ttcaaactgc tgcttctcgg taataagccc aaccaaacga aaaataggag gagctatttt
    43501 tgtttggctg ttcttatgac ttgatgcagg acagcttttt cacaacctct ccttacattt
    43561 taatggagcc gatcacttta ccagctgtca ctgtacctaa ttgcttgatc actacttctt
    43621 ctactttatc gtttgtaaat acgatcatga tcgttggatc tttttcttcg ttttggatca
    43681 catcaagatc catctcagct aatttcgttc ctgttcctac ttcttggcct tctttgacag
    43741 caatctcaaa agctggctga ttcatttgga ctgtatcgat tcccatatgg atcaaaactt
    43801 cgataccatc tttcgtttcc agcccaattg catgtttgct agggaaaata cttgtcactt
    43861 ttccagcgat cggcgcaaca acttctcttg atgttggaat aacagcaaag ccgtcaccca
    43921 tcattttttg tgagaatacc ggatctttta cttcagataa aggaatcact tctccagaag
    43981 ctgcggaaac tagttcttgt tctataccta agtattgctt actacctgct tgtccatttc
    44041 ctgtagaaac catttctggc tctggaatct ctgctcctga ttgcagcaga tcttcgatat
    44101 ctgatttcaa gacatctgct tttggtccat aaactgcttg gactccattg tctttgacga
    44161 tcaatcccat cgcccctgct cgtttccagg cttcttcagt ccctactttt tctcgatcat
    44221 ttacacttac gcgtaaccga gtcatacaag catcgacatc tttgatattt tcttttcctc
    44281 ccagcaaatg aatgatctgg accacttgct gatctgctgt tcctgttccg ctgttagata
    44341 caacggtttc ttcactgtca ttgtcgtaat ttccgttacg tcccggtgta gcaaagttga
    44401 attttttgat caagaaattt gctaagaaat acgtaacaac accaaaagcg atcacacaca
    44461 acacgaagtt gataagatct ccacctagac ccgctttgat agctaacggt gtccgagtca
    44521 gcaattcgat attcccaaat gaatggaccc gcaatggcaa gatatctgcc atcgcaaatg
    44581 cagccccttg gatcactgaa taaatgacat ataatggcac agcagcaaac ataaacatga
    44641 actccaatgg ttctgttaca cctgttagaa agacagccaa cgctgctgaa aaatacattg
    44701 atttatatct tgctttctta tcaggatcga cattacgata catcgcaaaa gccattccca
    44761 tcaagatacc tgaagaacca atcatttgtc ctactttgaa acgagccggc gtccagttat
    44821 gcaacacaaa ctcatattgc gacatatccc ctgcaccttt aagattcact aaatcagtgg
    44881 cccaagccaa ccataacgga tcttgcccaa atacttgtgt ccccgcctgt gcgcctgata
    44941 aaatctcata cgatccgcca agctgtgtat agttgatagg aatcgtcagc atatgatgca
    45001 atccaaatgg caatagtaaa cgttctaatg ttccaaataa aaacggtgct agaatcggtg
    45061 cgctttcttg tgattctgca atccataaac caaaattatt gattccagcc tgtacgtttg
    45121 gccacaccac agcaagaatc aatgccacga ttgttgacca taagataaca acaaacggaa
    45181 caaagcgctt tccattgaaa aatgacaaag catccggcaa ttttctataa ttatagtact
    45241 tattataagc cattgccccg acaaatccag cgatgatccc tacgaatact cccatattca
    45301 aagctggtgc ttccaataca cttgtaaaaa atcctttaac catgatcttc gtaccgaaca
    45361 gagtgtgggt aaatgcatct tcattcgcaa gcatgtcact tgtgacacca aagatagccc
    45421 cagtgatccg attgattaaa ataaatgaga tcccagctgc aaatgctccg cctgctcttt
    45481 cttttgccca acttcctcct attgctaaag caaataaaat atgaagatta ccaataattg
    45541 cccaaccaat attttcaatt actccgcccg ttgtgacaag cggcgtccaa tcaggattga
    45601 tcaagggaat tgatttccct atactgatca tcaacccagc tgccggcata actgctacca
    45661 caaccattaa agcctttcca aatttttgcc aaaactcaaa actaaatatc tttttcattc
    45721 cgtttagctc ctttacgcaa tcggtttcgt taaacgtatt atagcgtgcg ttttcttttt
    45781 tgtaaatgct ttatttttta tttttctgtc tataccattc tataaaacct ataatacgtg
    45841 tgttcccttc tataattttc tcctaaaaat ttattttttt aagctttttt ctatgaaata
    45901 ttttcttttg tctattgact tgtgcaatcg gttgcgttta ttatgaacgt ataaaacagc
    45961 tcattaggag gagaaaaatg aaacagatca aacgactatt tgctattgat ccatggaaaa
    46021 tcagcacgac acaattagat aaaaaaaatc ttcgactgca agaatcttta acaagtattg
    46081 gaaacggtta tatggggatg cgcgggaact ttgaagaaac ttactcaggg gaccaccatc
    46141 aaggtactta tttggcgggt gtctggtatc ccgataagac acgtgtcggc tggtggaaaa
    46201 atggttatcc agaatacttt ggaaaagtga tcaacgcctt gaactttatc gcgatagata
    46261 tttcgatcaa cgatcagctg atcgacttgg cttctttgga accagaagac ttttactggg
    46321 aattagatat gaaaaatggt gtattatctc gtacattcac aatcactact tctactaata
    46381 aagtacgcat ttccttcgaa cgttttctga gcattgtcaa aaaagaatca gcttatatct
    46441 atttaactat agaaatgctt gaaggtagcg gaacagtcaa actcgtatca aaattggatg
    46501 gaaatgttca aaacgaagac agcaactatg atgaacattt ttggaatgag attgatcgtg
    46561 gaactataga agaaatcggc tatttgacga ctaaaactat tccaaacaac tttgggattg
    46621 aacaatttac tgttactgca gcaatgcgcc atttcgttaa tggaaaatca gtcatccctg
    46681 actatcacga agatacttta gcattacatg gttgcttgtc tgcagaatta tctcaaggtg
    46741 agacatggtc agtggaaaaa gaaattatcg ttcttactag tagagatatt ccagaagcgc
    46801 agcaagcaga aaaagctgtc tcagaattaa cgaaccagac aaacaattat atccaagcaa
    46861 aagaagagca aacagcggct tgggcagaac gatggaagct tgccgatgtg gtcatcgaag
    46921 gagacgaaga agcacaacaa ggtattcgat tcaatttgtt ccaactattc tctacttact
    46981 acggcgaaga tgaacgattg aatatcggcc ccaaaggatt cacaggagaa aaatacggcg
    47041 gagccactta ctgggataca gaagcgtatg ctgtccctct ttatcttgct ttagccaaac
    47101 ctgaagtaac taagaatctg ctgaaatatc ggcataatca actgccgcaa gcaatccaca
    47161 acgctcagca acaaggatta aaaggcgcgc tttatcctat ggtcaccttc actggtgtcg
    47221 aatgccataa cgagtgggaa atcacattcg aggagattca ccgaaatggc gcgattgcct
    47281 atgcaatcta caattatacg aattacaccg gcgatacgga atatttgaaa aatgaaggac
    47341 tggaagtttt agcagaaatc gcacgcttct gggcagaccg tgtccatttt tcaaaacgag
    47401 caaataaata catgatccac ggtgtgaccg gcccaaacga atatgagaac aatatcaata
    47461 acaattggta tacaaatacg atcgcagctt gggtcttgcg ttacacgcga gaaaattatt
    47521 taacttatca aaaagaagct gctatcacta tcagcgaaga agaactagcc aaatggaaag
    47581 atatcgcaga gaacatgtac ttcccagttg acgaagaatt aggaatcttt gtccagcatg
    47641 acacattctt agataaagat ctcatgcctg tatccgatat tcccacaagc gatcttcctc
    47701 tgaatcagca ttggtcttgg gacaaaatcc ttagatcttg cttcatcaag caggcagatg
    47761 tactacaggg gatttatttc ttcaatgata cttttacaaa agaagaaaag caaaaaaact
    47821 ttgatttcta tgaaccaatg actgtccatg agtcttccct ttcgccaagt atccattcga
    47881 ttttagcagc agaattagga atggaaagca aagctgtaga aatgtaccag cgaacagctc
    47941 gcttggattt ggataattac aataacgaca cagaagacgg cttgcacatc acttccatga
    48001 ctggtagctg gttgtcgatt gtccaaggat ttgctcaaat gaaaactgcc catgatcagt
    48061 tgagattcgc accatttctg ccaaaaactt ggaaagctta ttctttccat atcaattatc
    48121 gcggacgttt attgttcatc tcagtcacag atgaacaagt tactttcgag ttattagaag
    48181 gttttcctct agaaatttac gtctatgaac agtcttattc tttagcggat cgtctagaaa
    48241 taacgctaag aaaggaggaa gcaaatgttt aaaggggtat tgtttgattt agacggtgtc
    48301 attaccgata ctgctgaatt ccattatcgt gcttggcgaa agcttggtca ggaaatcggc
    48361 attacgatcg accacacatt caacgaacag ctaaaaggcg tcagccgaga agactcactc
    48421 tctttgcttt tagcttatgg cggaaaagaa cactcttttt caaaggaaga atttgcagaa
    48481 ttagcgaaaa gaaaaaacga ttattattta gagatgatcc agacgatcga accaaaagat
    48541 gtcttccccg gggtcgtgcc tttactggat tctttaaaag aagaaaaaat caagattgct
    48601 cttgcttctg caagtaaaaa cgggccattc ctacttgaaa aaatgggtct tacaccttac
    48661 tttgatgcta ttgccgaccc ggcagaagca acaaacggaa aacctgcgcc agatatcttc
    48721 ctccttgcag caaaagctgt cggactaaaa gcagaagaat gtatcgggat cgaagacgcg
    48781 caagccggta tccaagccat cctctcaagt ggcgctcaac caattggcgt gggacgtgct
    48841 gaagaccttg gagaggagat cccgcttgtc cctgatacga cttttcttac gatcgattac
    48901 ttgaaagaaa agtgtcatga ccatggataa tccagagatc tccgtcgtac cagttccaga
    48961 gactgaaata aagaaaatca cattgaagaa cgactactta gaagtcgttc ttctcaatta
    49021 cggtgcccgc ctgcaccaaa tcttcgcacc agacaaagaa ggaaaatcag aaaatgtttt
    49081 attgtcttac gatcgtttcg aagatgttct aacagacaaa agcttttttg gagcaactgt
    49141 cggacctgta gccggaagga tccgggatgc ttcttggggt gagcatagat tggagaaaaa
    49201 ctgcggatca caccatatcc acggtggcac gaaaggctgg tctttccaat tttgggaagt
    49261 agaagttttc aaaactccat catcaatagg tgtggtcttt tacttaaaag atgaattttc
    49321 tacctatcca ggaccaatca ctgctacgat cacttaccgt ttaacaaaaa acgaattaga
    49381 gatgacaacc tctgctagta gccttgttga aaccatctgc aatccgacca accatgccta
    49441 cttcaacctt tcaggaaatg gaacaagaga catctatgaa catcagttaa cggtcttttt
    49501 agatggtgtg cttgaattag atcaagaaaa actgcctact ggaaattgga caaaaaaaga
    49561 aaaactgcca atcgacttta gaaaatcccc aacactgcaa gagatccttg catgttatcc
    49621 agatggacta gatgatgtat ttcttttgca tcatcctagg ctttccaaaa cttccttaca
    49681 attattcgag aagcattctg gtcgccaaat gactatagca acttctaata aaagtatggt
    49741 attattttct acgactggat tcgaagctga tttctctgtc aatggaaaac agatgcattc
    49801 aaactacgga ttagcaatcg aaccgcaaga aatccctgat atcgttcatt tccccaaatt
    49861 tggatcgatc aacctccatc ctggtcaaga acggatcagt cagacgattt atcggttctc
    49921 tgcacaataa caagagaaag gtgtttttat catggctatt accgtaaaag atgtggcgaa
    49981 aaaagccggt gttgccacct cgaccgtctc tcgtgtcatc aacgatcatc ctagtatttc
    50041 cgagacaaca aagaagaaag tccgaaaaat tatggatgaa ctaggttatg ttcctaacat
    50101 gactgcccgc aatctaggaa aacgcatttc cagtgccatc ggcgtaatct taccccctct
    50161 tgattcaaaa gagcggatcg gtaacccatt ttatcttgag atcatggaag caatcaacga
    50221 agaagcgcgg aattatgata tgactacagc aatcgctact gctaaaaatt ttgaattgct
    50281 gttagagaac gtccagcgta tgcatttaca aaaacaagta gatggtttta ttctagtgta
    50341 ttcagatagt caagatcctg tcattgatta tttataccaa aaccacatcc ctttcacttt
    50401 gatcggacag ccttatcatc atgagaacga aatcgtttat gtagataatg ataaccagct
    50461 tctaggtaaa caagcaacag aatttttgat ccagaatgga cataagaata tcctgtttgt
    50521 gacaaacacg actcatgaaa gtttgtattt cgaacgatat ttcggttatc aaaaagcaat
    50581 gatgatggct ggtcttcctg cgttatccag tgtagtacta gagcatccgg aggattatct
    50641 gtcctttgag aaaacgttga aagaaaacga agccacagca ttggtggtca ttgacgatat
    50701 cttcgccctt cgcacgatgc agttggcgca aatgtacggc tatgtcattc cagagacact
    50761 ctccgtcatt agcttcaaca actcgatctt ctcaacatta acacaccctt accttacaag
    50821 tatcgatatc gatatctccg aattaggacg tgtcgctatg caaaagctgc gcgaattgat
    50881 ccatgaagaa ttgagcagtg gcgtacgttt ggtcatccct catcgcttga tcaaaagaga
    50941 gacagtcgtt cctttagaaa acccatacta aatagctgac tcactaaata cgctgaccat
    51001 ttatcctatg gtcagctttt tatgtaaaag aagatactac ttctaacaca ttgtttatct
    51061 gtaaaaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    51121 aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttaaaa
    51181 agcaattttc ttgagtttct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
    51241 ttttccttcc ttcaattttt tacacgtcga cgattcaata aaaaaccgcc taatattgta
    51301 aagacaggtg caagaatcga gaaaaagacg aatggcaagt aatgcaacgc gctaactttc
    51361 atcgttccca taatgaatgt gccgctgact ccccacggta cgagagaatt gacggtcgca
    51421 cctgaatccg ctagtgttcg tgtcaaatag gtttttgata agccaacgtc atcaaaagaa
    51481 cgcttgaatg tttctcctgg aagaatgatg gacagatact gttctccaac gatcagattg
    51541 attccgatac agctcaaggc agtaaacccg actaaacgag aaggtcggtc catcttttct
    51601 tttaattctt gaacgatggt atcaacgatc agatatttga tcagtaaccc acctaatgcc
    51661 aatgcaagta aaatcaaact agcagaacct aacatactca tgatcccgcc tcgagaaagc
    51721 agttcatcta gctttggatc aggtgtattt gcgacataac cattcatcaa gatgtctgct
    51781 gcttttccga ccgtcaaact tttctcatgg ataaaagaaa gaacgagagc agctgtcgat
    51841 cccgctagta atgtagggat agccggaatt tttttgattg cccccccaaa taaaataact
    51901 agtggaatca atgtccaagg agagatccaa aagctcgctt tcatgttttg gatcatttca
    51961 ttgatactag ctagatcggc tgaatgactg ttatgtccta atatcgtata aaaaatcaac
    52021 gaaaggacga atgctgggaa atccgtataa cgcataccag cgatatgttc gaatagatta
    52081 actcctccaa tacccgctgc caagttggtc gtatctgata aaggcgagca gttattccct
    52141 aaaaaggcac cggaaacgac tgcgcctgta gtcattgcat cattgaatcc aagtaaatga
    52201 ccgatcccca aaaaagcaat tccaatcgtc gaaatcgttg taaatgaact gccgacagtc
    52261 actccgacaa ttgcacaaac aagaaatgct gtcggtaaaa agaaacgcac agaaacaagt
    52321 ttaaatccat aaaccataat cgtagggatg gttccagata aaatccatga agcaactaag
    52381 acaccaatca aaagaaaaat caggattgga atgatccctg gagtgattcc tttgatgatc
    52441 ccgtcatgga tctcatccca tgtgaacttt ttaaatctgc cataaaacaa caaacacatg
    52501 aaagctgcaa ggatcgggat atgtggcgag agctggaatc cgatgatcag tactcctagg
    52561 agtgccaaca acacgatcaa tacagcgata ctttctttta aagaaatatt tttattcatc
    52621 gtcgatctcc tatttcaaat gaaaaggccc tgccatgaaa aaactattca cttggcagga
    52681 cctcctacta aatcagcgac aaaacgtcgg ctgaaagact tatttttttt atttttcttc
    52741 taaacttttt tctacctcaa tcccccaaga atctttcttg aagtgattga tgatcaatgg
    52801 aataacgaac atgaccactg tgatagctgc tactaataat gcatcactca atgtcgctgt
    52861 acctaatgta gcaaatacga caacgatgat agagaagatc agcatgcagc tgactaccca
    52921 agctaatccg tttccgtttt taccaattcg gtaaggacgt tcgaattctg gatgtttctt
    52981 acgcatttta agcaatgaaa cagcaatcaa aatgtacacg atacaataaa taacagttgt
    53041 agcatttgta agtgtcaaga atacagcact tacgtcatcc attacaccat aaagcaaagc
    53101 aaataatgaa ataacgattg attgtgttag aacgacattt ctagatacgc cgtatttgtt
    53161 ttctttatgg aatccgaatt ttggtggaag gaatccttca cgagctactt ggatgattgt
    53221 ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc acaccaataa ataccatgaa
    53281 gctgaagata tttccgatca cttctggtaa gcctaggatt tgacagtcaa tcaagatagg
    53341 ctgcgtgata tttgctaatt ccatttttcc atctggtacg acatttgcta caagcatcgc
    53401 attgatgaca ttcaataaaa ctaatccgat caaagcgata aatacgcctt ttgtataatt
    53461 ttttgttgcg tctttcaaac gaggcatgta aacagaactc atttcgatcc caacaaaaat
    53521 aaatgtgata ccagctaagt atttcaatga atcaatatgt tccaagtcag ggaaagcttt
    53581 tgaccatgaa aagtcaccta gatagccgtt tgagactagt ccgactttga aggctgccaa
    53641 aacacctaaa acgaacatga tgactactgg gatatatacc cctagccata caccgatgtt
    53701 cccgccgact tttgccatat cgaatttcaa gttcaagatc gtgatgatcc agtagataac
    53761 taaaatacaa cctaaaacga accagtgatt attgccaagt tctacattac caaatgtgtt
    53821 tcctaacaat ggtcctaaag tagaagcgac cattaccata cctgggaaca tttgcaccca
    53881 taatagccat gcaacgacaa atccccattt gctgcccagt gctgttttta cccataactg
    53941 aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg gaaaccattg atatcggacc
    54001 ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat gtccaaccga ctgcggctaa
    54061 cgtaggaata ctccgaaccg ttgcacacag tgccattgtc agaccgataa aggtcccaag
    54121 acccatttta cttacttcag atttactcac cgttgacact ctccttgatt ttttggataa
    54181 aataacggtg tctttgaagt agtttcagca ataaacgaaa caattcagcg aatatttgag
    54241 gggattcttt gagtctattg cttgaagggt ttcttcaaag acaacctcaa aacaaaggga
    54301 tcgaagagct taggtctccc cttgctcttc agatccaaac atgcgtcaga aacagttagt
    54361 attcaagctg ttttctaaca tgattacctt gcttattttg cttcgcttgc caataattgg
    54421 tctgcgtaga ttttttccaa tttttcttga agagctgctt tgattttttc agcatattct
    54481 tcaaagtgtt cttctttgtt catgtatggt gtcattacgc tggcacgcaa tacagttact
    54541 tttccggcac ggttccattc ttcatctgag aatcctagtt ggttcacaaa ttgtaatggg
    54601 ctgttgccat agtctgggat agcaaagtca gtatgtgaag ttaagaactc attaccgtaa
    54661 atgcttcctt tcacgtatga agaataatca tatacgtcat ggttcaattt attcattgca
    54721 actaagtcat cgttgccttt ttctttgaat acatagtcta ccatattgaa atctggataa
    54781 gttaatggat gaacttcgat ttctttgtct cctactttaa atgacaagtc attcaagaag
    54841 ttgtagaaac gatgtgcacc ttcgattgat gcacccatta atttaccata tcctgtgaca
    54901 ttcaaaggta agacatggtg tgctgcccaa acgctggctg ctgttgcccc tgcttttgaa
    54961 ccttccaaga tataagcccc aagtaatgct gggatatctg cgcctttttc aaatacatat
    55021 gtcgcaaagt aagagataac gtctctcatg cggatatctt tgatgacgat accaccggca
    55081 gaatatggaa catagcccat tttatgtggg tcaatcgtta cagattctgc ttcttcgatt
    55141 gctttatatg cactgtgtac ttcttctaag atataatctt tgttttctgt aaagacattg
    55201 tatttgtaat gaacatcttt taaatcttca aatggaatga agttgttgtc ttcgtctaag
    55261 aaaatcgcac ggccgtatcc gccataagca gcatctacgt gtaagtagaa gtaaataccg
    55321 tctttttcta atacgcgacg caatgcaacg attttatcga taccgtcgat tgctccttct
    55381 tctgttgatc ctacaacacc gactacacct aggattggtg ttttttcagc tgctagacca
    55441 cgaacgattt tttcaagttc gttgatgtcc atgcgatagt tgtggtcaac tggcactgga
    55501 atcacttggt ctaaaccgat accgatgatg tcggcagctt ttagccatga atagtgttta
    55561 gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt ttccgctacg tgctgagtga
    55621 gctttgattt cgtcgatttt ttctgggacg ctgtctaaca gattcatgat ttcttctgtt
    55681 gacaagttca ttaattccca atcgcttttt ccagcaacta gttcaggtgt cacttctttc
    55741 attgcaagcg gcaatgattt gatgttgcgg gcataccaaa gtccttctaa gtttgctaaa
    55801 gaaccatcag caacgatgtg gccccagcca tctttatagc tcattaattt tgcaaattcc
    55861 attcctactt cttcttccat ttggcttgtt gcaggagaag attcataggc aacgttatta
    55921 ccattccata gcatagcaaa attgtacgct agtaaagatg gcatcaatgt ttcagagttc
    55981 atatgacccc agtaacgtcc ggcattatgc caaggaacgg aatgggtacg catccgcgct
    56041 gaaatttctg atagaacatc ctttgtttta ttcacagtgt gttcaaaact agcactgctt
    56101 ttttcttctg gcgtaataat aggcatgtct tgaggcatgt agttttgacg ccagcctaaa
    56161 tgttcatcca ccaattcatt caacaaagct ttatagattt ggccgttctc agctttgtcc
    56221 ccaatgaata gggcatttag gtttagatct ttcgacaatg attcactcat agtgaaaccc
    56281 tcctaaaaaa atatttaaat tttgtcgagc cctacattac acctgttctt ctattctgta
    56341 aactaagttt tggcctgatt tttaatcata ttttaatatg tatcaattat ccgaattgtt
    56401 cacacttttg aaataattaa aaaaaacgag ggaatttaca aatgtaaact ccctcgcaaa
    56461 gattgtatta acgacaacca gcgttctatt ttaggatggg tttcaaaatt ggaatgttgt
    56521 aatagtattt ccctttttca aggtaaaaac ttactaaatt ctaatcaatt actttggcca
    56581 aaaagtaatt tttcttacct tttcgaataa ccacaaactt accatcgaat tcatcggatg
    56641 gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt aatacttata gctccgtttg
    56701 aaacatcttc acgtgcttga cgtttagatg gttcaatttt tgtggaaaca agcagttcca
    56761 cgatattttc aggtgtgctt gaaatttcaa cgttcggcat tttaccgaat ccttgcgcga
    56821 tttcttccgc atttagttct ttaatatttc cagagaacaa tgcttgcgtt attttttgcg
    56881 cttctttcaa gtcttcttca ctatgcacaa atcttgtaac ttcttctgcc aaacggcgtt
    56941 gtgcttcacg tttctcaggt tctgtctcta cttttttcgc taagtcttcg atttcttctt
    57001 gagacaagaa agtaaagaat ttcaagtatt tcactacatc gcgatcatct tgattcaacc
    57061 agaattggta gaactcaaat ggtgaagttt tcttcggatc aagccaaacg gcaccgcctg
    57121 cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa tgggatcgtt aaaccgaacg
    57181 cttctacttc tggtccttct aattttcgga ttaggtctaa tccagctgtg atatttcccc
    57241 attggtctgc tccaccgatt tgcaattgca catcgtatgt tttatgcaga tgcaaaaagt
    57301 cgatagattg cagaatttgg taagtaaact ctgtaaatga gattcctact tccaaacggc
    57361 tggcaacgat atcttttgct aacatcgtgt tgatgttgaa gtttttaccg tagtctctca
    57421 aaaattcaag taaagagatt tttgacaacc agtcgtagtt gttcacaaat gtgatatttg
    57481 catctttacc aaacaatttt ctcatttgat tggaaagtgc gtccacgtta tgttgcactt
    57541 gttccatcgt ttgcaacaca cgttctgttt tgcggccgct tgggtcgccg atcgttcctg
    57601 ttccgccgcc aatcagaata tatggatgat ggcctgccaa ttggaatctt ttcatcatca
    57661 taaatggaat caaatgtccg atatgcatcg aatcaccagt tggatcaacg ccgcaataaa
    57721 gtgaaatgct cttttcttca acgagctcgc gaagtctttc ttcgtttgtt tgctgattaa
    57781 tggcgtcgcg ccaagttaat tcatcaataa tattcatttt actgacctcc gtgtagtttt
    57841 tttatgaaag caggaacctg ctagcatgtg taattaatta tttcttcagg ataggatagg
    57901 aaataaaaaa agtcccttgg catataagcc aagggacgaa atctcgcggt accacccaat
    57961 ttgtatgtct agatatccaa catacctctc gaacatttaa cgctgtcgcg tggcaatcac
    58021 tgccaaagac tcctgaaatg taattcgctt taaagcatgt actggtttgc agcgaccacc
    58081 agctttctga aacattggct ttaacaacta cttcgtttcg atcttcgtct tgttattatt
    58141 aatatgtgtc tatcatagag cgcaactttt tctttgtcaa cagaaaaagg atattttttt
    58201 taaattcctc attttttctt ttttgaatcc gctctaattc cgaacatttt attttcaatt
    58261 attgttaaaa gaaataactt tttctgtatt ttttctgcaa tttatcgaga agtcacttta
    58321 ctttgcctct tattctttct tcgttacaat aaggaatggg acaagtaaaa aaatgaaaaa
    58381 gcaagggacg aggtatatgg aaaaaaagca aaaaattatt ttaggagcca cttctgcttt
    58441 aactatcgtt attttaattc taagtttgtt ttttgtcatc cgatcatcta caaaaaaaga
    58501 accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa gaaccgacag atgataagca
    58561 acaactagtt actcaagcaa aaaatctggc tcaaagctac gattatgacc aagcgattgc
    58621 gttattggaa aaagatagta agaacggatc tactgaaaca caacagcttc ttcaaacact
    58681 aaaaaaggag aaagaacaac tgatcgactg gtctgatcct actcagatct ctcatgtctt
    58741 tttccacagc ttgatcgtgg acccgcaaaa agccttccac tctcaacagg cacaaggata
    58801 caaagattat atggtgactg ttgaagaatt caaccgttcg atcgaacaac tttatcaaaa
    58861 tgattttgtt ttagttaatt taaatgattt gatccaaaaa gacgaacaag gaaatctttc
    58921 ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg gttctttcac aagatgatgt
    58981 cagctattat gaatatatgg ataattccgg ttttcctagc cgattggtcg tatcaaataa
    59041 caatgaaatc aaaaatgtct ataaagagaa agataaagaa gaaatcggtg actttgacat
    59101 ggttcctctg atcgatgcct ttgtcaagaa acatcctgat ttttcttatc gaggcgcaaa
    59161 aggtaccttg gccctgacag gttacaacgg agttttaggt tatcgaacat caaaatctca
    59221 atatggagac aatgaaaaaa caaaaaaaga gattaaagaa gctaaaaaag tggcggaaca
    59281 gttgaagaaa gacggctgga gctttgcttc ccatacatgg ggtcacttga atatgactca
    59341 agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg cagcaagaag ttgcacctat
    59401 cctaggaaaa acaaatattc tgatttatcc atttggtgca gacatcagcg actggcagcc
    59461 ttattcagca gaaaatcaaa aatttgctta cttgaagagt caaggtttcg atattttctg
    59521 taatgtcgat gcttctacac cagcttgggg acaattaggt acggatttct atcgaaatgc
    59581 tcggatcaat atcgatggca ttcgttttca atctgattta gacggaaaaa atcctattct
    59641 tgatccattc atcaatgtcc atgatgtcta tgacaaagaa gcacgcgaat ctgcttgatt
    59701 ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt atcgtcagtt tcggcttttt
    59761 tatgctttat ttcttcttcg gtgcgattcc cttgatcagg acttctgtcc attctgctgt
    59821 atatggaagc agttttgcgt atatctccgg cttagaaatt ccttctacca ttgcttgaaa
    59881 atagaggatc aagaactcat ccgaatattt caaatccact tttccttctt tccgccctcg
    59941 atggaaaaga tcaagcatga tactgaaact ttcttgcgta tacgcatcca tcgcgtcaga
    60001 aaattctttt ttttcttttt ttgtatagta tgtcatcaaa tcgatataaa attgtttgtt
    60061 cactcgattg agataacgga ttttgttttc actcatggca atcagtgttt cttcaaatgg
    60121 aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa tcattcataa atgcaaaaaa
    60181 tacttcataa atcagccctt ccttgctgcc aaaatattta aaaatcgtcg ctttacttac
    60241 ctgagcgttc tcagctacct tatccattgt cactccagcg gttcctatgt ctgtgttcat
    60301 caagtcaaaa gctgcttgta aaatctcttt ctttttctct tgtgctctct tttcaaaacc
    60361 gttcatttgt agagcctccc gtaattttaa acttttataa tatatatagt tcaaatttat
    60421 tctgaggttt attataacta tctattgaga aagtatcaag ctagcaattc cttgtttatg
    60481 aattcattga cagaaattta taaaaagaat attatgtact aaaataataa aaaaagtttt
    60541 ataaaaaggt ataaaacctt tttattaaac tatttaatct tgtttagtat atatttttag
    60601 aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc acacatttga aaaagagctt
    60661 tggtcgtttc gaagctttaa aagatgtctc tttcaccgta cattcaggtg aagtcgttgg
    60721 atttatcgga ccaaatggtt ctggaaaatc cacgacgatt cggacacttt tagggattat
    60781 aaaaaaagac ggcggaacgg caacgatttt tgggcaagat gtatgggaag atagtttatc
    60841 tatccatgaa cgtctttctt atgttccagg cgatatctct ttgtggggaa atttgactgg
    60901 aggagcgatc atcgatctct tcatgaagct tcatggaaaa gggagtgctc aaaaaaaaga
    60961 tgaactgatt caacgtttct ctcttgatcc taagaaaaaa gcaaaaaact attcaaaagg
    61021 aaatcgccaa aaagtgggct tgattgctgc tttggctgtt gattcggatc tctatttatt
    61081 tgatgagcct acttctggtt tagatccttt gatggaaacg attttccaag aagaagttga
    61141 aaaattgaaa gaacagggca aatccatcct actttcttct catattctca gtgaagtcga
    61201 gcgactagcg gataaagtcg tgatcatacg cgaaggaaca gtcgtagaag aaggaacact
    61261 cgatgaattg cgtcatttga ctcgttcgac catcactata gaaacagaag cagagaatag
    61321 tcacttagca caattgaacg gtgtccatga ctttgtgcaa aaaggtcacc tcgctcaatt
    61381 tgctgctgat aacgaagctt tcgatgtgat tttagctgaa gcgtccaaat taggtgtgaa
    61441 aaaatttgaa tctattccac cgactcttga ggatttattc atgagacatt atgaaggatg
    61501 aggaggaagc gaaatgactg ataaattttc acgctggtcc accctttttt ctcaaaacct
    61561 tagccgtgac tggaaaaaga tcctgatatg gctagtcggt gtcactgctt tttctggtgg
    61621 ttttgtccct gcgtttgaag aattgacttc cggacaagga ttagctggat tatacgaaac
    61681 cttgcaaaac ccggcaatga ttgcaatggt cggaccaact ccagcttcga atgctgctga
    61741 gtatacttta ggagcgatgt atgcaaatga aatgttgctt ttttgcagtt tgtttgctgc
    61801 tgtgatctct gttttacacg tggtgagcca aacgagaaaa aaagaagaac ttggtctgat
    61861 tgaacttatt cgttcctttc gagtcggacg tcaagcaaac tctttagctg tcatcgctga
    61921 aagtattctg atcaatttgc ttttagcaat atcgatcagc tgtacgatga tttttttcca
    61981 agcagattcg atcactgcag aaggtgcttg gctttttggg ctatctgtag gtagtatggg
    62041 gattttgggg agtgccgttg cactgtttgc tgcacaactg atgccaagtt cagccagttc
    62101 gaatggtctg tctttagcgt ttttaggtgg actttacctt ctacgagcaa taacagatgt
    62161 agctgattcc tccctttcga tgtggaatcc tttaggctgg tcttatttga cctatccatt
    62221 tacaactaac aactggattc ctttgcttta tttgtttttg ttcagtctaa tcttgataat
    62281 cagttcattt gttttagagg aacatcgaga tttgaacacc ggctatatcc ccgaacgtga
    62341 aggaaaaccg tatgctaaac gttctctttt atccttgcgt ggtttattat tctatctaaa
    62401 taaagggatg acaatcagtt ggcttatcac ttttggtttg atgggggcgg catacggctc
    62461 tatctacggg aatatgcaac agtttttaga aagtaacgac ttaatgaaac agatgtttat
    62521 ccaatctggc gtctcaattg aaaaaaactt tacaagcacg atcatggtcg tcttgatttg
    62581 tctagctgct attttaccaa ttgctagcat caatcgttta tttacagaag aaacccacgg
    62641 acgtatgaat cagctgttcg caacaaaaat ttctaggaac caactttatt ggaccaatat
    62701 gttactagct attctatttg ctatattggc aatcctgatt agttctggtg cactagggct
    62761 ttctgctttg gcttcgatga aggatgcgaa agacatggat ctattgatgt ttcttaaagc
    62821 cgggttcaat ttcctgcctg ccgttttagt gtttatcgga attagtggct ttctattcgg
    62881 atggcttcct cgaatgggta aacttgctta tatctactta gcttactcct ttgcactcaa
    62941 ttactttggc ggaattttgg atttaccaga atggttttcc aaaacagctg tccctagctg
    63001 ggttccacgg atgccaaacg attcttttga tctttccgtg ttccttacgt tatcatgtat
    63061 cagccttgca ctgttcgtcc ttggttctat tggttatagg cgaagagact tactagaagg
    63121 ataataaaaa agcatgtaca atttcatgct agcctccaaa tctgggtcaa aaatccaaca
    63181 tttggaggtc atttttttat ttacaagtct tctaactgct ctttatcaat gatccagact
    63241 tctcgattct ttctttttac ataaccattc tcctctaata atttaaattt tctagataaa
    63301 gtttcggggg tcgtaccgat aaatgcagca agttctttca ttttcattgg caggaaaaag
    63361 tgatccttcc ctgtcgcttt agctaagtca agcagataga cagcgactcg ttcttctact
    63421 ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg ttaatttctc aacgttgatt
    63481 gctaaaagtt tcagactaag ggcgggataa tgcagtaaga gttccgagaa atctttttgt
    63541 ctcaatatgc aaatttccgt tttttctagt gcttcgccaa ataaagactc atttggaacg
    63601 cctagcaact ggctctctcc ctcatatccg cccggctcta ttactcgtaa aagctgttcc
    63661 tttccgctag cagataattg atacactttc atactgccgg aggccacgat cactaattga
    63721 ggttctccat tcggcgcaag aatctgttct cctttttcca catagtgatg tttgacaagt
    63781 gcgtgtactt tttcttgatc ttgctgtact aagtgattga acaaaggaac aaatgaaaca
    63841 cataaatgat catgactcat aatctctcct ccttctaaac agctatttct aataaagaaa
    63901 cataacttcc cttattccaa ctgataattt tcttttatca tagcataaac gtcaagcgaa
    63961 ccagatacca gcaaatagag tggatttctt tttgtccctt gctttatttt ccttcttttg
    64021 agaccttaag taattgattc ctatcaattt tttaaatatt tactttttga ataatcaaaa
    64081 acaaaccttc actcgcaagc cgagagtaag gtttgttttt cgcattgctt atttcgtgtt
    64141 gtctattgaa atttttccgc acctagcttt tgatatagtg gtgctagttc ttgtaaggtt
    64201 tcagcggtta tttgctcaac gtgttcgatt tcttgcggat agaagaatag tttacccatt
    64261 tgaaaggttc ggtctctcat cgcttttttc aactcttctt gtttctttgt atcggacaaa
    64321 tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg gttgcggcca tatgtaataa
    64381 tccttgatat cgactgtttt gctccactct ttcagtatcg caagcaactg gttatacgct
    64441 gcaatgctac catatcgttc ttcgctttta taatgttggt acatcaaata gatttggtat
    64501 tgtttttgat tcaacaaaac tgctagacag gcattctcgt cttgacgaga ttcgcttcgg
    64561 tacgcgctcc aaaaatgact gcgtaaattc cagccattcg tccagctttc gattttaggt
    64621 ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct ggagctgaat ctctttccat
    64681 ttttgccagt gttctttata ttctttcttg atttgttcaa tcttatctgt tggatggctc
    64741 tctttgagct gtttgaatgc gtagattggt cgatcaaaca actgataatc tgattttcca
    64801 agttccattg tttcgcctct ttccgttatc ttttgtattc tacctgaatt ttgcgatatg
    64861 gacaaataga ggttgtgaaa aagctgttct gcatcaagtc ataagaacag ccaaacaaaa
    64921 aactgcgatg agcatcaccg cagttttatt gaacttaagg ttgattgatc acatctaaaa
    64981 gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc gatatgtccg attgcacgct
    65041 ctcctagata ggaagctcgt ccttttttag ctaccaagac tttggtgtgt tcttttgcct
    65101 ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc ctctgtgact ggcagccaaa
    65161 catctaacat cgttttatcg tcagcttctg cctttcctcg gctttgaata cccgctgttc
    65221 cctgctcgat cacttcgcct aatttttctt gagaatcaat agaatcgacc tcttttgtcg
    65281 ctttcatcat gttcatgaat gcagatccgt ataacggacc agaagcccca ccgactttcg
    65341 atatcatcgc catagagaat actttgaatg tatcgctgat tgtttcagga tgatcggctt
    65401 gaaaagcttc ttcataagct gaaacccctc ttcccatgtt atttccatgg tctccatcgc
    65461 caatcggggt atctagatca ctgagatatt gtttgttctg attgattgcc tctgcaaatt
    65521 gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat attatcaccc ttttatcttg
    65581 agatttttta ccatgaaatc gtctgtacat tgctttctaa agaatctttc cattgtgtct
    65641 ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc tagtgaggtc ataaaattac
    65701 cgacttttcg gaaaactaca ttgacgcctc tttcttccaa cagagctaaa acatcattca
    65761 tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc gttgactagt acacctgctt
    65821 cttttggtaa attcgagtaa tcatctaaaa tcttagtaac aagttccttt gccagtactt
    65881 tagaaggctg catcttttct cgacgatagc ctggctcacc gtggatacca acaccatact
    65941 cgatctcatc ttctcctagt tcgaatcctg gtttccctac ttctggtaca gttgctgctc
    66001 gaagcgctag accgatcgtc ttagttgcct gtacgacctt ttctcccagt tctttcaact
    66061 cagctaggga agcaccgttt cttgctgcat cgcccacgat tttgtgtaca aggacagtac
    66121 ctgcaactcc gcgttttcca gcagtatacg tactattttc aacggcgata tcatcatcta
    66181 cgatcacact ttctacttca atatcgtcca tagcagctaa ttcctttgcc atatcgaagt
    66241 tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac tccttttcca ctatccgctt
    66301 ccttaatagc cgtctgaatc tgatctggag ttggagaagt aaacacatca ccaagcaccg
    66361 ctgcacttaa catcccttcc cctacaaacc cggcatggga tggttcatgt ccgcttcctc
    66421 caccagaaac caaaccaact tgttccgctt tctgattctt ggctacaaca cgggaagatt
    66481 ctacacgatg aacaagttct ggatagcttt ttactaatcc ttccagcatt tcttcgacaa
    66541 tattgcttgg atcattcatg atttttttca atttattccc atcctttctt tccggcattt
    66601 tgtgcttctg ttaagatttg ctgagtatca tctgttatac cggcagtgat ggctgctgca
    66661 aaagctcctt ccactaaagg cgcatccacc agatgataac gttgctgctg ctcttcttcc
    66721 aacatgtctt ttgccagttc cgagttcaat accgcgctac cgatatccgc aaaaacaaaa
    66781 taactagctg catcgcttga ttcattgact gcttctacga ttttcatcgg gtctgatccg
    66841 atctcgccat ttattccgcc gagagaaaaa atttgcacct cttcggattt ttgcatctgc
    66901 tcaatcattt ctttaatacc atctgttact ttttgactat gagaaataag caaaatactt
    66961 tttttcacaa gaatcttcct ttcttttaca tagttgctaa cgattggttt cgctttcatt
    67021 aatgaacaat tcaagtatat aataaatttc taattttggg aagatatgtg tagtgcttct
    67081 tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg aatgattaca acaacaacga
    67141 acagtgtaga gggaaaagcc gtagtagctt ataaagggat cgtttttggt gaggtcatta
    67201 ctgggatcca tgcatttaaa gacttggagg cggggttgcg aaatatcttt ggcggccgct
    67261 caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga agcacttgcc gaaatggccg
    67321 aacgtgcaaa agcattagga gctgatgcga tcattggcgt aaaaatggac tatgaagtat
    67381 taggcagcga caatggcatg ctgatggtca catgtagtgg aacagctgtc tccacgagat
    67441 aagtagggga catctgtttt aataactaaa gagagatggg acatgtagtg gcactcaaga
    67501 attagatttt tcagtctaac ttcgaggtac tctaccttcc catcctctct tttttatttc
    67561 tttttgcgga tgattccgta agctgctgcg actaacacac ccgcccctgc taaggaataa
    67621 ctgacagaag ctgttttttc atttgttttt ggcaaagtct gacttgttga tttggatggc
    67681 tctgtcgttt gctgaactgt ttctgtcgtg cttccagagg tcactgattt ttctcctgcc
    67741 gaatgcaaaa tatcttttat tcgttggaaa ctagctgcta agtcagcttt ttttgcttca
    67801 aaatcattag caactgtttg tgcttcgctg atctttccgt ggattgcttg actggccgct
    67861 gtgatatccg cttgagtttg acttagcttt ccagaagctg tttgagcaac ctgatttaat
    67921 tgctgattga attcttttgc ttgttggatc ttcccgtcaa gatctgtttg gacagcttcc
    67981 gcttttgctt tcgcttcggc aagctttttc tcaagttgtg cacggtcatt tcccacttta
    68041 tttttaagat cagctaaatc ttgatcgatt gctgcttggt cttctttcaa tttgtttttt
    68101 gcagcttcta atgcttcttc gagttctttt cttttatttt ccaagtcttg caaatgatcg
    68161 atttggtcag aagaggtaga actatttatt gatgtatctt ctgaagatga aatcgtttct
    68221 cctgaattat ctgtcggtac attggaagtc atttctgttt ccgaggcacc gttttcagca
    68281 ccagaagagc ttatagttgt tgaaggttct gtttgagcag gttcagaagt ttccgcaaaa
    68341 gctgtctgtc ccaataagaa aatactggaa acagcaattg gccagattaa cggcttcatt
    68401 ctttttttca tcacttttcc catccttact actttttaac taatttctta ttataagcaa
    68461 aaatgtttgg aagaaccata aacacaacag gctgtttgtc taaaaaacgg tgcatctttt
    68521 atttttttgt acgttccggg cttttccatg tcccgcttcc ataacctaaa atcgttttga
    68581 ctgctggaat gaaagtcgtc acgatcgtta tcgcgttcac tatccagaac aaaagcatat
    68641 atagtggtgc gaaaagaagg tatttcaatt ttcttcgtcg atcatctaca atcagcgaag
    68701 ctagcaactg gaaaaatcct gcgaccattt caaagcagat gaacacaaaa ctgaatgtaa
    68761 aagtaatata aatctgttcg tagtttcctt gatatacata atgcccgatt aatccagcaa
    68821 aaagaactac ggaaatacaa aagaatattg accagacaat actcaatgtt tgatcaatga
    68881 agatgatcgt tcttccaata tgtttaaaag gatggagcat cacttttttg aaattcgtca
    68941 gccagacttc tgttccacct tttgcccaac gttttctttg tcgatatagc atcttcaacg
    69001 tcacaggtac ttccatgaaa aagataatct caggagcaaa aacagataac cagtcattta
    69061 actgatgatc ccaagcaata ctgatgtctt ctgtcgctcg atcttgtctg aatccgccca
    69121 catcgatcaa ggcttctttt cgatacatcg tatttgctcc actgtacgca taaagaccac
    69181 cgaaaacagc tgactgtgtt cgtttaatga tgcccacgat acttgagaat tcaaccgttt
    69241 gagattttgc aatcaatttg gtacgatttt ggacatccat atttgcagtg accgcagcaa
    69301 tatgtcttgc accagggcga atgaaataat tcacatacct aatcagtgca tctggctccg
    69361 gtaccgtgtc tgcatcattg cttaaaatca atttcccttt tgcaaaggca agtccgatat
    69421 taaacgcgtg ggcttttcct ttattttttt cgatccgaac cacacgaaga ttagcgtatt
    69481 ttttcatcag tctagctaat atttctggtg tttggtccgt tgaaccatcg tctgtcacta
    69541 atacctcata gttgtgataa ttcaatttcg tcatcaaata ctcgattgta tcttcgatca
    69601 caatttcttc attatgggct ggcaccatga tcgtgatgaa cggttcgaca ctcaagggaa
    69661 catctaccca ttctttttgc ttatgtttgt ataaaaacac ataacaccag acaccaataa
    69721 accatacaaa tccgcctaaa atcggataag aaacgagaaa aaatacataa tagacaaaca
    69781 agtatctaag aataaattac ctgtatgggt gattgagatc atttcagttc caccccattt
    69841 tctttataca aatctgcaat gaatgtcgta tctagatttt tctcttcgga gacagaataa
    69901 aaacggaccg tttctctctc ttcttttgtt ccaaaacgtt ccgtatacac ttcttcaagt
    69961 aattcttgtc tttttttcaa tttttcatct tcatattcaa aagatttatt tacttttttg
    70021 tatagatttc gattgttcca cctagtcaat acaaatgagg taatcaggaa actgaaaaaa
    70081 atcaatacaa aaaagccgat taagaaatac agcattttct tttctgataa aaaagcgtac
    70141 aaggaaaaat ccttggctct ttctggtctc gttaatggga aaaagaccca tataaaagga
    70201 agaacaacga tcatccatcc taaaagagcc actaacgttt gccaaatctt taaccagtaa
    70261 ttaccttttg aaaaatactt atctttcacc aaaattgatg caacttcttc tcttgttact
    70321 tttttcatat cctcacctca cgtttttttg ttacgacgta ggagtttacc atacatttca
    70381 tttcttttca cataaagtgt tcctaaattt ttcctaagaa aaagaacaaa acatttctca
    70441 tcagcaaatg aaaaatattt tgttcttttt atcagttgtt ctttttattt tttatctctt
    70501 aattatgttg ctctttccaa tacgacaatg cttttcattc ctctagatat cgccgtgtac
    70561 atttgtctgc gtcttctttg ctcatctcca tcgttttcaa atggatataa gattacatga
    70621 tcaaattcca gtccttttgc tagactcaaa ggaatgattt ggcagttttc taatccatat
    70681 gaattttttt taatcgattc ttgtagcgtt tgggtttcct cttctgtttg ggtgataact
    70741 gccgcttttt ctccttttag agaaaccaaa atctcagcta gtattttcaa caattcttca
    70801 gaggatcgaa aagagcggta ttcgggttct tttccttgcg gtcggatcga tacgatgtcg
    70861 atcttctctt gatccacagc ataggttttg aaaagctctg tgattgctcc gctagaacgg
    70921 taactatttc taagatcata ccgatggatc ggcagatggt agtcgtcgaa acaacgcata
    70981 atatcagcaa aagtagtgga agaattaaag attgcctgat tctcgtcacc tactaaagta
    71041 aagtgagttt ttggaaataa ttcgatcaat agacctaatt gtgccagggt ataatcttgt
    71101 acttcatcaa tcaatagata gcgaaatgct ggtacattta ccttttcaac aagtaaatga
    71161 cgaatagcta atataatgac tgcttcatca acagtacgtg tgggttgcca agcataagct
    71221 gagccatatc gtttttcata aattctttca aacaactgat gctcatccac ccatgccatt
    71281 tcttcgattt gtctggttat ttttcgatat tttttttgta aaagtttcct tgcataagct
    71341 acaatacttt gttccgaatc atcagaaatc aatttaccga ataattccaa ctgcctatct
    71401 tctgtcaacg agagtacctg attctgcaca gcaggacttt ttgcttgttt caaaagatga
    71461 ttcttccatt cgctcatcag tgcctttttc gttgcttgaa gcctatcgat caatttagga
    71521 tgagcaggaa ctttctcata tattttttcg atcgtttttt tagaaaggac tgtttttcca
    71581 tttttagtaa gtccacggat aaaattcgga tgatctaaaa acaaaggatc tgattgtttt
    71641 agattatcga taaacttttt gctacgcaaa cgttctgtct gctccgatac attttctccc
    71701 gtgatacgtt tgaaataagc ctcttcacct tctatttcct ctgctgaaag ctgtgaaacc
    71761 agctgtatga tggttagatt cagtggattt ctttcaccta atgatggtag gacattcgaa
    71821 atatagtcga taaaccgatg attaggtgat agaatcagca agtcatcgga tgtcatcgta
    71881 tctcgatata aatagagcag atacgcaata cgctgcatga tagcagaggt tttaccactt
    71941 cctgctacgc catttaccaa gatattttga cttttcacat cccgaatgat tgtgttttgt
    72001 tccgattgga tcgtagcagt gatagccttc atttcattgg tctcatcttg gcctaagact
    72061 tctaataata cgtcatcttg aatagctaca gacgtatcaa aaaacttgac caaacgatct
    72121 ctttccaaaa gaaattgtcg tctttcttta ataaccgtat cgattttatt ttgacgaacc
    72181 gtataagaag atggaccaat catgttattg taaaaaagtt cggcaattgg tgaacgccaa
    72241 tcataaacaa gattttcatc tgcatcatct gtgaaatttg ctgtaccgat ataaaaggat
    72301 tcttttggct cattatccag aaagtctaca acgacttttc caaagtaggg acttttcaat
    72361 aaacgttcga tctttgctag ctgattttct gcgtttttct gtttgatatt catctgatcg
    72421 atttctctat ttttcatttc aatcatcgaa aaagtatcca ggttatctaa gtaactgtca
    72481 aaattcaatc gaagctcgcc agccatttct ttcaacgact ggtttccttc tatttttgcc
    72541 gtatccatcg attcccgcag ttcgtttttt ttatcaatta gcttttgata cacgttcttc
    72601 agatatgctt cttctaactg tttttgtgtg ttgaccatac acattctcct ctttttttaa
    72661 agtggtggac ccgattagtt tacctctttt aagagtcgaa tgcaagcttt ttaacgagta
    72721 tcatttgtta ggatatatca gttcttcagg tcggacagtt tgatataaag aaaatgcacc
    72781 atcaaggttt tttacgtggt agccagactg cttcaagatt ctttccgcta gatagctacg
    72841 taatccgcta tgacagctga cgatatattc ttgttggctg tctaattcat ttaatcggtc
    72901 ccgaagttca ttcaaaggga tatgtttggc ttccttgaat ttgccctttt ccaattcttc
    72961 tgctgttcgc acatctaata aaatttttcc ttttgctagt tctgtcggca attcatgcca
    73021 ttgtacggtt tcactaagcc cttctgcaat gttcattgct gcatatccta gcatgtttac
    73081 tggatctttg gctgagccaa atggcggtgc atacgtcaat tctaattccg gtaaatcgaa
    73141 gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg atccgtttat ccacaccttt
    73201 tgccccaaca ccttgtgcac cataaatctc gccagtctct ggatggaaga tcaacttcag
    73261 taaaatatct gttgcttctg gataatagct tgcatgatct tttcctgata catgaatgac
    73321 ttcaaaagac agttcgtttt ctttggctgt tctttcactt aaaccggtgg atgcggcagt
    73381 cattccaaac gttcgtataa ttgctgttcc aataccgcct tgatttcttc gagaaattcc
    73441 ggaaatcgtg tccgcaactt gtctaccttg acgattggct ggtgaagcaa gagaaataag
    73501 tgcatctttt ccagtgattt gctgttttac aacgatagca tcccccaccg cataaatatc
    73561 aggaatattc gtttgataac gttcgtctac taggataccc ccgcgtatgc ctaattcgat
    73621 tccagcggtc actgctagct ggttatcagg acgaacacca atggataaaa taactaaatc
    73681 agcagggatg gtacgcccat catccagtcg caatcgtttc ccgtggtctt caaatccagc
    73741 gacagcatga gaagtaatca cttctactcc ttgatgagac aattcttttt ctataaaagc
    73801 tgccatttct tcatccagtg ttggaagaat atgtggtgct tgttcgatca ccatgacttc
    73861 taaacctctt ctttttaggt tttctgccat ttccaatccg atgaatcctg caccaacgat
    73921 cacggcacgc tttggctgtt tttctaatgc atgcatcact ttatcgatat ctggtacatt
    73981 tctaatagaa aaaacattgt cggcttctgt tatccctgga atcgatggaa caactggttt
    74041 tgcaccagga gataaaacca atgcatcgta ctgttcaatg tgtttttgac cctcatgtac
    74101 gacttctacc gttttgtttt cgggaaagat ggctgtcact tcatgatttg gacgcacatc
    74161 taaacaaaaa cgagcggata atgattctgg cgtttggaca agaagatttt cccgttcact
    74221 gatttctccc gaaagataat aaggcaagcc gcaatttgca aaagaaacat acggtccttt
    74281 ttcaaaaaca acgatttctg catcttccat taatcggcga agccgtgtag cagcagacat
    74341 tccacctgct acacctccga caataacgat tttcatctta tttccctcct actgttcgat
    74401 caaaccattg attcatgcca ccacgtacat tcactacatc ataaccagat ttctttaatt
    74461 ctttagctgc ttgtttactc ctcatccctg attgacaaat cacatagacg gtcttttctt
    74521 tgtctccatc atatctgttt atactttgta atggaacatt tttagctcct tttatatgcc
    74581 cgccccggta ttctgcaggt gttctaacat caagtaacgc tggattttcc aaaagctttt
    74641 cctttaattc tgggactgtt atcgatttta ttgattgaaa tagcaaattc attttctgca
    74701 cctcatttac atttttataa atacctcatg gggtatatta aacaggagct ttattaatat
    74761 gtcaaccaga atgactcttc atttttttca ctacttttta tatttgcata aaataccgat
    74821 aaggggtatt atctaattat aaaaatagag gagaatgtgt tatggagatt gataataaaa
    74881 atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg tggtatccaa aaaatgatcg
    74941 aagacgaaaa agaatgtatg gatgtcatca ctcaattaag cgctgttcgt tctagtattg
    75001 atcgcgtaat gggcatgatc gttgcagata atctgaaaaa ttgctttgag aaacctgata
    75061 gtaatccaga agaacaagcg gctaaactag aacaagcgat caagatgatt attaaaaagt
    75121 aaaggaatga tttcaatgaa agtcgttttc catattgatg aattagaaaa atggtcagaa
    75181 acagggaaaa acgtaaaaaa cctgataaaa gcttctccag aaacgacgat tgtcgtatct
    75241 gtaaatggca tcgcgattac cggttatcta gactctgcca atgcagaatt cttagatttg
    75301 caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg ctaatcatat ttcagaaagt
    75361 tctttacctg aacaagtaat cgttgtacca gcaggtgtcc ttgatttagt tgaactgcaa
    75421 tcccaaggtt atgcttatat caagccttag tcagtagagg ttgcgacaga agtgatcagc
    75481 ttcaagaaat ttcggcttat ttttcgaaga agctacttct ggaaaaccgt gaatcaaagg
    75541 ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agcttctcat
    75601 atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc gtttaaggaa
    75661 gaggttgtga aatcagcggt ttgacctaag tattagagaa aaaaacggga aaatagctcc
    75721 tcatattttg ccgttttttg agctaatacc gaaggtcagc tgattgaaca ccgtttaagg
    75781 aagagattgt gaaaaagtcg cttagtttcg agtattaaga aaaattttgt gaaaatggat
    75841 ttctacattt ttgcataaat ttggcttaat accgagaaac tggcttttga ataccgttta
    75901 aggaagaggt tgtaaaatca gcggtttgac ctgagtatta gagaaacaaa cggaaaaata
    75961 gctgctcata ttttgccgtt ttttgagcta ataccgaagg tcagctgatt gaacaccgtt
    76021 taccaagagg ttgtgagcct accatttaac tccgaatcac aagaaataat ttcaaaaaca
    76081 acttctcctg tttttggttt ggttggctta ttatcgagaa gtagctactg ggagtctatt
    76141 tatcaaaaaa aggaatgcga cataggtcac accccttttt tattttcttt gaaacatctt
    76201 tcggtactcg acagcataca agacaaaaga ttgtaaaaga ccgtaagtga tgacggcaaa
    76261 aatgactctc acccacagcg ttggtaattc tgggaaaagc agcaaaagga tcatgccaac
    76321 atagatgaca gcagtcgcta ctttgccata ccacttcgct ccacttaatt tgatattttt
    76381 agatagcccg attaatccag ctacaaacat aaagccttct tttatcaaga atagaccaaa
    76441 caacagccaa agccacggtc gataccatgc catagacaaa atcagaaaaa gttgtgtcaa
    76501 tttatctgca aacggatcaa gcaccttccc taagtctgtt acctgattat atctccgagc
    76561 aatgaccccg tctagataat cagacaaacc tgagacaaca atgaccgctc ctgctatata
    76621 aaatgactgt ctcagcacaa aataaagata aatcggcagc aaaaaaatac ggaatatcga
    76681 taaaagattc ggaatcgttt gtatttcttt acgccagtct gtgcttaatt tcattttatc
    76741 gccctacctc ctcagcactc ttttcttttt attttagctt acacggggaa taaaaccaat
    76801 gatttcactg tttttatttt tctttacagc cactgatatt atgagctaat ttgagataat
    76861 cacttgctgt tttcatcgtt tactcttctt tcttcctgtc gtttgcgcat ttcttttact
    76921 agtactttat gagctttttt tgatcctcgc tctaggtcac gctgccgttt acgtgtttta
    76981 taatcgataa acagactgtc taaatcgtaa cctgtcgggt acagatcttc tgctgaacgc
    77041 accagacgaa cacgctgacg aggcacgtgg attatttttt tgtctaaata tacatcaatc
    77101 gtatcttcac ctatatcttc ataaactaac gcttcttttt ggtattcatt gacaaatatc
    77161 cgatcacctt ttgcaaagag ctggcgttct tttttattct ccttcctatt tgtaactgct
    77221 gtcttaggaa gaaattcttt tttctgtgtc cgataggctt tttccgccaa gtaacgctct
    77281 gcttgatgga tcaatttcat cgacatatcc attttatgag caatccacaa agcttggctt
    77341 tctcctgttt ctccaacccg caactgatat ttaggacgaa gtgcttcccg atcgaaagcc
    77401 atagcagccg gcacaaaatc ttcatgatct ccggcgaatt tcttgatttc tccataatgg
    77461 gtcgtggcaa tgatcaatgc cccttgctca tacatagatt ccatgattgc gatcgctagt
    77521 gcagcccctt catttggctc tgttccactg ccaatctcat ctaaaagtac caacgtattc
    77581 ctttttatct ttttcaaaat agcagcgatg ttttgcatat gaccagaaaa tgtactcaac
    77641 gcattttcta aattttggtg gtcaccgaca tcgacgaaaa tctcatcaaa gacagcaagc
    77701 tctgtccctt cttttgccgg aacttgcata ccgaacatcg ccatcaaagt caataaaccg
    77761 actgtcttca acacgactgt tttgcctccg gcatttgctc cggtgataat caagcctcga
    77821 tagtctttac cgatttcaac atccaatggt accgcatgct caggtaaaaa tggatgtctg
    77881 ccttgcttga taatgatatg ttccgattta ttgattctag gtgtgcttcc attgatttct
    77941 cggctaaatt ttgcccgagc aaagatgata tctaacaccg tgatcgtttc gatcaataaa
    78001 tcgatcactt cttcgttttc tgcgatagca ccagtcaatg ccgccaggac ttgatattct
    78061 tcactgattt cttcagcttt taacaactga tagtgttcat tcaatttaga aatcacagtt
    78121 ggttcaataa aaaccgtcgt tcttttattt gattcatcga taatcgttcc atctatttta
    78181 tttttatagc tggctttgat aggaatcgta tagtattcgc ctttttgaac aatcattgct
    78241 tcttggatca tttctttgtt tttcggatga cgcaagaatt tcagtaattt tgactggatt
    78301 tctttttcga ttagttgtaa ttgtttgcgt actttacgca aattacgtga cgcgtcgtca
    78361 ctgactttat tattttttat tttctggtca atcaactctt ctacatttat caaatcagga
    78421 agatgtttgc tataagcaaa caacaagggt gtctggtatt gattcttatc aaaaaacttt
    78481 gtgatcatcc gactgcttct aagaaaatcc gcatattcga tcaaatcggt tggctgcaga
    78541 atcaaccctt ttttgacttg ttctgtcagt gcatcgatcc tcggcaaccc cataaatgga
    78601 acatgctgac tgctttctaa gatcaagcgt gcttctcttg tttcttcttg acgatccaag
    78661 acagtttgta ggtttgtcga gaccgtcata tcgctgattc gttttttgct atagtttcca
    78721 attgctcttg cttggatttc ctttttgatc cgatcaaatt gtaattgact aatcatttcg
    78781 ttgtccatat tctctccttt tcttgaagag atacctgtcc caaaataaat aagggcctag
    78841 agataaataa aaggatagaa cacagcttaa aaaagtcatg tcctatcctt attagaatac
    78901 aaagatattg ttttcctgac aggtaccgtt tcataagcac accaaataaa ctttgtttat
    78961 tggctattcg acttactgat tagataccag ctacactcac aaaacatacc ccattcttct
    79021 aggtcttatt tattttccac ttaactatag caagacacat tttggttgtc aaactttagt
    79081 atgttttata gatttacacc attaatgaat agacacctac cgcgataatt gctccgatca
    79141 ttggacctgc gattggtacc catgaatatg cccaatctga agttccttta ttagctattg
    79201 gcaataccgc atgtgctaat cgaggaccaa agtcccgagc agggttgatt gcatatcctg
    79261 ttggccctcc taatgaaaga ccgatggcta agatcaatcc acctacagcg aatacgttcg
    79321 ttccaggtgc aaattcgttt tgtccaaaag ctagcaaccc aagaactaat acaaatgtac
    79381 caattaattc tgtgatcaca tttgctggat aattccgtat agcaggacct gttgcaaacg
    79441 ttcctaaaat cgcgctttca tctttcgttg cattccaatg tggcaaataa gaaagccaaa
    79501 caagaatggc ccctgcaaaa gctcctaaaa cttgcgcaat gatgaaagga acgacaagat
    79561 tccaactaat tgcccctgtc atcgccatag ctagagagac tgcaggattc aaatgagctg
    79621 ggcccatgaa tccagaaata tagacagcca ttgttacagc gagtccccaa ccaaatgcga
    79681 tgacaatcca gccagaagcc tgtgctttac ttttgtttaa attcacagcc gcacacacac
    79741 catctccaag caaaactagg atcagtgtcc caataaactc tcccatgatt tgagtcatat
    79801 cactgttcat ttatttctcc ccctttagtt cccgcagatc tgattctgca atcaatgctt
    79861 ctaaacgttt agtctgttgc gccttctcct cttctgtcca ttcaaaatat ccagcaattg
    79921 catcgatcac aggttgcttg atctcatcaa gctgatctcg ttcaaacaac agatgatttg
    79981 tacgacgaat gagataatcg cctggggcca aaaccatttc ttcttctaaa ccataacgta
    80041 accgagctga ctcagcgaga ctcaaaccag gataaggtgc catttctttt gctaattcaa
    80101 agatacgtcg ggcattagtc ccgtaaaaat cagcgatata agtagcatct tcttcctcta
    80161 aaccggctgc tactccttct tttgctaatt ctgtcactgt ttcttctaat ttagttggat
    80221 cgaagtttcc acctgaaatc tgatattttt tagagtcgat ttctttcgtc tctattccgt
    80281 attcttcttt taataattgg cgtatcaatc gcaaagctcc ttctgccatc ttacggtaat
    80341 cggtgatttt cccaccagat aaagtcagca aaccatctgg ttctctttct aaagaactac
    80401 ctctggaaat cgtagaaggt gctttttcat cacggctgtt ttccaaatgg ttcaacacgt
    80461 cttctacttc agcacgagaa actttgtttt ccttatattc acttactgta tcgacaactt
    80521 tattgaagct cttgtctgaa atcgatccat tatctccacc attgtaatca gaaccagaat
    80581 taccaatcaa cagtggacga agtcctgccc agcttgcttc gatatcattc aatgtgatat
    80641 ttgcttctgg atagcgatga ttgatcacat ccaatagata atctacatct tcttgtgtga
    80701 ctttcggatc cgtaaaatct ccttggtaat ccgtatctgt cgtaccaaag taagtcttgt
    80761 tttctcttgg aatagcaaaa accatccgcc catcttgctt tcctgtatcg aagtatgtgg
    80821 gttgcggtac aggcagtttt ttcgcatcta caactaaatg gatcccttta gttggacgca
    80881 ttttaggaga gactggacgc gtaaaattca agtttcgtac tttatctacc caaggaccac
    80941 tcgtattgat cactaatttt gctttgattt cgatcacttc atctgtcagc aggtcacgag
    81001 ctttgacgcc aacgatttga tcgccatcat ataaaaagcc aaccgctttc attttactta
    81061 ctagataagc cccatcttcg gcagcctttt tgatattatc aatcactaaa cgggcatcat
    81121 tgttgcggaa atctagatag acacccgcgc cttttagccc ttcttttttc aaaaacggtt
    81181 ctctttccaa tacttcttct ggtgtcagcg tataattctc atatttggtt cctgtcacat
    81241 ttgccagttt gtcataaagg tccattgcta ctttgaccga gaacatattg aaggttgttg
    81301 ctccttcgcc ctcatagatt ggcaaaagca ttggatctgg ttttgggatg tgtggggcaa
    81361 tactttgtac gactgcacgt tcaccaactg tgtcagctac tacttccaca tcaaatgtct
    81421 tcagataacg aataccgcca tgaacaagtt tggtcgagcg agaggaagtc ccttctgcaa
    81481 aatcctgcat ttcgatcaat cctgttttga ttcctgatgc tgctgactgg actgccacac
    81541 cggcaccagt gattccgcca ccgatgatca acagatccaa ttcttcttgc tgcatttttt
    81601 gaatgctatc ttgtcttgtc ttgtttgaaa acatatggat ttcctcctta ttcaaatgct
    81661 tgggtagctt ttactgcttt tttccaaccg ttgtaaagtt tttctcggcg ctcttcctcc
    81721 atttgaactt caaatagctt gccagcttca taaaattcgc ggatctcgtc tgtatctttc
    81781 caataaccga cagctaatcc tgctaaaaat gctgccccta gcgccgttgt ttccaagttt
    81841 tctgctcgtt ggatcggtac attcaagata tctgtttgga attgcatcag atattcattg
    81901 tttgctgcac cgccatctac tttcaataca ggaatcttga ttccagtgtc atcttgcatc
    81961 gtatcgatga tatctctcac ttgataagca atcgactgta aagtagcttt aatgatatct
    82021 tcttttgtcg taccacgtgt caagccaaac atagcccctc gtgctgcctg atcccaataa
    82081 ggagcaccta gcccaacgaa tgcaggaaca acataaacct catcttcgct tgtagagcgt
    82141 ttcgctgcgt cttctgaatc gctagctttt tgcaacattt gaagtccatc tctcagccat
    82201 tgaatcgaag aaccagccac aaaaatactt ccttctaaag catagtaaac ctttccattt
    82261 atgccgtaac caattgtcgt caataaatta tttttggata attgcggttt ttcaccggta
    82321 ttcatgacaa taaatgaacc tgtaccataa gtattcttga ccatgcctgg ttcgaatgcc
    82381 atttgtccga ataatgcggc ttgctggtct cctgccatcc ctgaaattgg tgcttcgctt
    82441 ccataaaaat gataaccttg cgtataacca taaacttctg agttagaagt gacttttggt
    82501 aacatcactc gaggaatatt tagtaaatct aaaatctcct gatcccaatc tagctgatgg
    82561 atattgaaca acatcgtccg actggcattc gagtaatcag taacatgtgc ttgtccatcg
    82621 gtcagtttcc atactaacca agaatcgatc gttccaaaca tcaattcgcc tttttcagct
    82681 cgttcttgcg cgccttctac atgatcaaga atccagcgta tcttcgttgc tgagaaatag
    82741 gcatcgatca ctaaccctgt tttttcgtgg aaaaattctt gatagccttc attttttaag
    82801 ttatctgcaa ttccagctga ctgtctggat tgccaaacaa ctgcatgata gattggacgt
    82861 cctgtatctt tttcccatat tactgttgtt tcacgctggt tcgttatgcc aatcccagca
    82921 atctgatttg gtttgatccc tgattcgatg aacgctccgg caataactga ctgtacagaa
    82981 ttccagattt catttgcatc atgttccacc caactttctt gcgggaaata ttgcgtgaac
    83041 tctttttgag aactgccgat gtgtcttcct ttcttgtcaa agataattgc tcgtgagcta
    83101 gttgtacctt ggtcaatcgc catgatatac gttgattctg tcattgtgat tccctccatt
    83161 atatgcaaac gctttcttta actactctta tcatactact gttttaaaaa aagaaactgt
    83221 caaaatttta ttcttttttt ctttttttga cagtttttta ttatgaagct attttttaat
    83281 caattctttt cttttttcag cgtctctatt cttcttttca atcgaataat gtcgtaaggt
    83341 gacgcaaatt ctgacagata atattcacac tgttttttgt ttctctggca aaatgtgatc
    83401 accaaatcat attctttacc ttcttcataa cttccaatct caataccgcc gattcccctc
    83461 agttctctga tcagatattg ttgaaaagca atacgataaa tcggcagact ttctaaatcg
    83521 attccaatca ctactggttt tgcaatataa aaatcgatca tcaaaagaac attggcatac
    83581 tggatcatca ggtaactaag ctcactatct tcagctcttt tcctcggcaa ttgctgcacc
    83641 gctgtttcct gtaatttcgc cagtaactgt gttaaggaat gcccgagcat tttctgctgc
    83701 tgttccaaaa gccgatcacg ctcatagact tcgatctttc caacaaagaa aaaccattca
    83761 ttgttgatct gggaaatttg gtagcctact gccttttctt ctttgatttt caaacgacga
    83821 ggacgataat gccataacat cgtttcccga atgtaagtat ctaaaacagc ggttggtaac
    83881 tttttgctcc gtgtcaaatc atactgataa aatatttctt cgtctactat cgaaaaagaa
    83941 acaaaaaagc tgtaaaacat cattgtttcg tatacattca gttctgctgc tgttcgacta
    84001 agatgcatca cgatgattgg atcgattgct tgataaagcc ggtccgactg atagagtaat
    84061 ttcttttctt tcaaagttgc gtacgtactt ttttcattca atagtctttt tttcgtaatc
    84121 ccgagccagc aagcaatctg tgcttctgct gatgccgtaa acgttgtttc taatacacgg
    84181 tccaatccta gaatgaacgg tcttttttct ggtgtatttt gcaaaaaaag cggtcgctga
    84241 tcttccggga tatattggaa tagttcataa taaaaatatc gtatctgtag ctcttctccg
    84301 tataattgac cgtttttgat ttgtaatcca aattcctcta agagctggtt caattctttg
    84361 atctttcgaa aaacagaaga ctcactgata ttaaacgctg tcgctaatcg aacgatggat
    84421 acttgctgat gttctaataa atagacgagc atcttaaact tcaagctttc ctgcaataaa
    84481 aacaatagaa ttttttccaa acttacatct tcgtccaaca caagcagcgc ctgatactca
    84541 tttcgctgta cttctacttt tttttccatc attcggccaa tcaattcaat atcttccaaa
    84601 tattgatcaa acgaggcttt tgacagttgg acatgctctc tcaaaccatt gatagaggct
    84661 gttccccctt gcagaacaag gtttcgcaaa atcaggatct gtaactgctc ttttctttct
    84721 aataatgctt caatcttcat aggcagtatt cgccaccttt gaccacacca tatctggcac
    84781 acggtattct ggctggaaaa atagctcatg ttcttctaac tgttcaaacg tccatccttc
    84841 ttctactgca attgtcagtt ggtcaagaag gtggaacatc tcttttttgc tttggagctg
    84901 tgctccaaga atcttttttt cagaatcaaa tagaaatttg agtttaactt tgctttgatt
    84961 tattgctgta agcttgtagt ctacgtatcc tgtttcaatt ttttggggat aaaaaatgct
    85021 ctcttcttct gtcaaaccta cgcttcctaa gaaatagcca aaccactgat tgccgactgg
    85081 acgataggtt ccctgatcct ttgtctgtga gccactaatt gtcttgctga catttcgtgc
    85141 tgtacggaca gcgttattta ctagagaaac atacattttt tcatttgttg gacgaaaagt
    85201 tacttggatc gcatcgccaa tcgcataaac gtctttttga gacgtttgca agtagtcatc
    85261 tacccagatc gttccatcat cattcaatgt taattgttct tcccacatct gattgtcggg
    85321 gcgagaatga ttagccagca aaacaagatc atagttctcc tttctttttt ccgtctctac
    85381 aatagcggtt tcattttcgg tcaaagacac aacttgttct tctaaaaaaa gtgaaagccc
    85441 ttgatttttc atttccttta ctaacggttc tgtcatttca ggatctagat aacgaaaaag
    85501 aattgacttt cggctttcgt aaagatggat ttgttttttt cttgatgcca acccttcagc
    85561 tatttcgatt cctgcttgtc ctgcaccaat aattgcaatt ttctttgcat tcatgatctt
    85621 ttgctgaaga gccgttacgt tttgtatctt tttaactggg tgaataagcg ttgattctgc
    85681 agaaatattt cgaaactttt gatttgaacc agtcgctaga atcaaacgat caaaatccaa
    85741 tttttttcct cctgctaaaa cgactttttt ttctttcaat cctattactg tcttttctgt
    85801 gtaaacatgg attcgatagc ggtcagtcag ttcttctttc gtgatccaag aaagttgttt
    85861 ttcactggta acctttcctt ttaatatcaa attgaacccg ctgggaatcc atcctaactt
    85921 cgattgcttt tcaatcaaat atatttcact tgttggcatc aattggcgaa gataaatagc
    85981 cgcatgaatc cctgcaaacg acccgccgac aattacaatg ttcatctgca ttcctctttc
    86041 ttataaggtg ttctactgct aacttctcaa tcagaaaaca cagtattcat aactcgcttt
    86101 caaccttatg atacatagcg atgcagcaga atcaaccctc tccatcatac cgtgttctag
    86161 gtctgcttct caataatgta ctagtggacc taattgaaga gtatcatttc tgaagagatg
    86221 tttcaaaaaa tgtactctta taaaagaaaa aaactcgcct tttacgtacc tctgtccaaa
    86281 taggaaacag aaaagaacga aaagacgagt tttagcgtgt gtaatgtaat agttagaata
    86341 gacacatcat ttatttttaa ttctttaatg cttcaacaac tgcttcgcct aattgatgag
    86401 cagattgagg attttgccct gtaagaagcc gcccatcaat ttgaaccact tctgaaaaag
    86461 ctgctccaga ctgatagttt gctccttttt ctttcaaagc atcttctgct aagaatggta
    86521 cttcattcgt tgtaccattt gcttcctctt cttcattact gaacccagtc actgtacgtc
    86581 cagctaaaat agattttcca gactcatctg taactggcaa caatcctaca acaccgtgac
    86641 aaacagctga gaccagccct tcatttcgat agatttgtga agcgactttc ccaagatcta
    86701 ttgcttctgg aaaatcccac attgttccgt ggccaccagc ataataaacc gctgcataat
    86761 catttgcatc cacatcatca ggacgtaagg tatttcccaa ggcccgattt ctgaaatctt
    86821 catcttcata ataggcccaa tcgatttcat ccatattcaa aacactttgc ggttctaaag
    86881 gtacatatcc gcctttagga ctgacaaaat ctgcatcgat cccatttttt actaatacat
    86941 cataaaaatg agtcagttca cttaaccaca aacctgtagg acgctcgatc ttttcgtact
    87001 tttctacatt tgttaatacg atcaatactt tcattttccc atcctctttc tataaaaatt
    87061 gcgttattga taacgtgctt tcaagaaatt atataatggg cttggcaaat aaagctcttt
    87121 atatgcttct tcaaaaggtt tcgttacaaa ttcatcctca cggttttcca ataatttctc
    87181 tgcccagtca ggatcgacga tcatttgctg tccaattgct gcaagttctg catatttcaa
    87241 tacctgctct acatcttcgc gattgcggat cccaccgaca ccaactaaag ggatctttcc
    87301 ttgaatcgtg ttatggacca cttcaagaat cgatttatcg ttgtatttat cagaacgagc
    87361 tattcgatca tacatattta atgaaacatg cagataatct agttttgact cacgtaatcg
    87421 ttcaagaagc cagatcgtgt cttcaaaacg gatacctggt gtttcatatt cttctggtga
    87481 gaaacgatac cctacgatga atggtttttt agcatattgt tcaaccgctg agaaaaccgt
    87541 tgttaataat tcttcaataa aacgataacg attttccaag ctaccgcccc attgatcctc
    87601 tcgtctattc gaatgcggag agaaaaattg ttggatcaaa tacgtatttg ctccatgcaa
    87661 ctcgattcca tcaaatcctg attcaatcgc tctacgtgtg gctttgccaa atgcttggat
    87721 tgtttcaacg atttcttctt cactcattgc tcgtggtgtt tccgcatcag gacgttttgc
    87781 tgcaactgca cttgcagata caggctgttc tccagataaa gttgctcgac ttgtcattcg
    87841 tccaccgtgg aaaatctgaa taatcgcttt tgcgccttct ccttggattg ctttcgctag
    87901 ctcacttaat cgaggaatca tttcatcatg agcgatgctg agttcacctg gccagccttt
    87961 tccgatatct tggacatttg cagcaccagt aataacagca ccaagacctt tagaacgttg
    88021 tttataataa gtgatctcat cttcggtgat cactccattg aaaaagctga gttgtgtcgt
    88081 cataggcgac agcatcaatc ggttcttcaa ttgaactcct gaaggtaaag taattgattg
    88141 atcaaattgt gacattgtca ttcctcccat aattcgctct gattaaccta tcgagaatca
    88201 tctatcatta aaccactcga ttagttgtac atgcaactaa tttgcttaaa aaattttatt
    88261 ttttttgtaa cttatctgtt gcatcattca ttgtctgggc taattcttta cttgcttcat
    88321 ttcccaaaac tgctttgtat gactgatgaa gttcttccca gctaccatcg acttccttag
    88381 caaattggcg tccttgttct gtaagataaa ctaatgacaa gcgaccttcg ctaactgttt
    88441 tgacgtatcc tttatattct aatttttcaa caaaacgagc aatcgttgat ggggcggaat
    88501 agagcatttg tgcaatatct ttttgtggta ttccatcttt ttcttttaat atcaataaaa
    88561 taaaaccata agttggtgcc agacctgtcc ttctaaacgc ttcatcagct aatttattca
    88621 acatgcgatc tagctttttc acgctaaaga aaagacattc atctaacgct ttttcaattg
    88681 gcttttccat ttcatcccct ccattggcgt acatatcata gtatgatttt tattttttgt
    88741 caaaaaacac ggaataatgt ccgcctcctc tgtctagatt tgaaaaaaag aagtagccat
    88801 cttcaaagaa tttcggcttg ttttcgacaa aactccttct ggaacaccgt gaatcagagg
    88861 ttgtgaaaaa gtcgtttagt tttgagtatg aagaaaaatt ttgtgaaaat ggctttccac
    88921 atttttgcat aaatttggct taataccgaa aaactggctt ttgaacaccg tttatatcag
    88981 aggttgtgaa aaagccgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct
    89041 catattttgt cgttttttga gctaatgccg atggtcagct gattgtacac cgtttattga
    89101 gaggtcgtga gcctgccgtt gaactccgag tcacaaggag caatttcaaa aaacagcttc
    89161 tcatgtttta tgactatggt gacttgtgat cgaggagttg gcaggagaat actgtttatt
    89221 cgtaaagaag gggctgtgac aagacttttg tcacagtccc ttatttcctt ttattatagg
    89281 atttcgccat ttgattggat gacttgtctg taccaatcaa atgatttttt ctttaaccgt
    89341 ttctttgtgc cattcccttc gtcatcttga tcaacataga tatatccata acgttttgac
    89401 atttgtgaag tagaagcgct gacgatatca atgcagcccc acgacgtata accaaataaa
    89461 tctactccat ctttgatagc ttccttcatc tgctcaatat gctgtttcaa atagtcaatg
    89521 cggtaatcgt cttgaacggt tccatcttct tctactttgt ctatagctcc gagtccgttt
    89581 tcagctatga acagtggttt ttgataccta tcatataatt gattcaaagc aattctcaaa
    89641 cccttaggat caatctgcca gccccattca cttgatggaa gatacggatt tttaattcct
    89701 ccagttatta agtttccttg gaccccttcc caattttctg gatgagcact gactgcacta
    89761 gacatgtagt agctaaaaga aacaaaatca acagggtagg ctgctaagat ttcttcatca
    89821 cctacttcta tttttaagtt gacacctttt tcttcaaaca ttcgttgcgt atacgctgga
    89881 taatatcctc ttgcttgaac atcactaaag aacaaagaag ttctttgctg ctcaattgtt
    89941 ttttgaatat catccggatc acaagaatac ggaacaagaa gctgatagct gatcatacaa
    90001 ccgacttgtg aacctttgat aatttcatga caagcttttg tagctaaagc acttgctata
    90061 aactgatggt gtgcaccttg gtatttcgct tgttccaaat ggggatggtt ttcttcaatt
    90121 actcctacgc taacaaaagg gtgatgtttt acacagttga tctcattgaa agtcatccaa
    90181 tattttactt tatttttata gcgtttgaat actgtttcag cgaaacgaac gtaaaactga
    90241 ataagctttc gattaggcca tccaccatat tctgtaacca aatataacgg catttcataa
    90301 tgggaaagag aaacgactgg ctcaatccca tattttagac attcgtcaaa cacttgatca
    90361 taaaaaaata atcccgcttc attgggtgtt tcttcatcac catgaggaaa aattcttgtc
    90421 catgcgatag acatccgata gcatttaaaa cccatttcag caaataaacg gatgtcttct
    90481 ttaaagtgat gatagaaatc atttccgtgt cttttaggat aataatactt gctgttggga
    90541 tcctgcgccg cttttacttg ctgatgcgtc atcatatgcc attgatctgt ccatttttct
    90601 ttaggtaaat cgctgtcgaa tgtatacaca tcagacacag ataatccttt ttcatctaca
    90661 tcccatgcac cttcacattg attggccgct gtcgctccgc cccataaaaa tccttctgga
    90721 aattttttca tatcgatccc cctaaacttg ctagttttct tgtttgatta tttttcttat
    90781 gactagtaat gatatttttg aatctactac tatttgtaac aataaccatt gtggtcggat
    90841 catatccctc tttgattaat tcttgcaaat ctacttccat caataaatcg cctttacgta
    90901 ctttttttcc atcagatact gcactttgaa agtatttgcc atttaaattc actgtatcaa
    90961 taccgatatg gatcagtatc tctgctcctt cttcactgac taccccaatt gcatgtttcg
    91021 ttggaaaaac tgttgaaact tccccgttta caggactgta gatttttccg tccgttggaa
    91081 tgatcgcaaa cccttctcct aaagatccac tagcaaatgt tggatcgttt acttcagata
    91141 aatcaattat ttcacctgct gcaggagtac ttaacactat atcctttgag gattcttctt
    91201 cgatttcatc cttgtagccg aaaagaaaag ttagcataca ggaactgatc atcgctaaga
    91261 aataactagc aactagccaa acaaatcctt caccaatata aatcgggaaa gacaaaatac
    91321 ttcttgtagc aactgccaaa gcaccggctc ctgcggcacc agctactcca ccaaatatag
    91381 ctccacatat acaagcaatg taaaatggtc gtttatattt aagagtcaca ccataaacag
    91441 caggttcagt gattccaaat aatgctgtga taaatgcaga taaagataaa ctttttactt
    91501 tcttattttt cgttttcaaa aataccccaa gtactgctcc tgcttgcgca gctacggcag
    91561 tcatacatgc tggacctagc gtatcacgac cgtagaaaga aagattgttg gtcattactg
    91621 gtacaagtcc ccaatgtaac ccaaaaatca ctaacacttg ccaaaatccg ccgataacag
    91681 caccagataa aacagggcta aagttataaa cagctaaata tccagctgca atcagctgac
    91741 ttgcataatc tgcaattgga cctacaacta ataaagtaat tgggaccatc acgatgatac
    91801 aaatgaatgg tgtcaataaa tttcgaatac tttcgtgcaa gcttttgcga atcttaggct
    91861 caatataaga aagaacccat acagctaaaa ttgctggaat aaccgtactt gtataccttg
    91921 ctagaatcac gggcatccct agaaatcgca aggttatgct atcactatat gcactgacaa
    91981 tcgtaggata aacgagagct gctgcaataa ccatagcgat gaaacgatct gtattgaact
    92041 tttttgcagc agtatatgcc aaaaatatag gcaagaaata gaaaaatgca tcagctgctg
    92101 cattcaaaat gatataagtt cctgattcag tagttaataa attcaaactc gtacataagg
    92161 cgagtactcc tttgatcaaa ccacttcctg ccaagacgcc taaagtcggg gcaaaaacag
    92221 cggcgatcat gtctataaaa gagtttaaaa tgcctttttt ctcagttcct ctctttccac
    92281 tagatgcatc atcttctagt ttcatttgtt tggataatac gtcatacact tcatttactg
    92341 catttcctac tacgacttga aacattcctc cagcttcgac tacagtgatc acaccttcta
    92401 gttgctctac cttctcctta tctgccttct tattatcttt tagggtaaag cgtaaccttg
    92461 ttgcacaatg gtaaacattg ctgacatttt cttcgcctcc gacaaatcgg acaatatctt
    92521 tcgctaattg tgaatagtcc atttttactt cccccttgtt aattaatgcc gtagcaatcc
    92581 ttcttacaag ataagtatag ttcttagaaa acggtttctc cattcaatta gtacccctta
    92641 taatagcgaa cgaaactgta caatagtgtg tatggtttac ttagccgagc aaatcactca
    92701 ctgcttgaaa gaaaacaagt atatcgtttc tcttatagtc aaaggagaca aaaaaaacac
    92761 gcttgatctt cctttgctga tgtataagtg gtatctcaag ctgatactct gtgatttttg
    92821 tttctacttg gcttttgata agacagcaca acaaagtctc ggcatttaac ggaagcataa
    92881 ctaggtcaga actaggagag attagttgct gaatggaatc tatcttttta tggattttta
    92941 tttgattttc ttctttgtag taatgatcaa gcagttttgt tttctttttt tcttcaacta
    93001 tggtcagctt ttcacgcaaa atctgataaa tctcccaaga ttcaaactca tctagaacac
    93061 taggtagata aatcaaatca tcccactcaa aaataagctc ttgctcagta gtcaaaattg
    93121 catcatattc cgttattttg tttgattgat ttttgaaaag atacactggt tctatccggc
    93181 attctttgat ccacatgttc atactttgtt gaatctgttt ttttagtgta ttcaaaatac
    93241 taattggctg gttactaaca atcagtatct ccccttgttt tcgaaaagga ttcaacgctt
    93301 cggcaagata caaaacaaaa taagcgcttt cagctaaatt gggacgtaat tgaaaatgta
    93361 ttgggaagaa acgccgaatt aaataaattt ctaaaggata acgggagatg atcttttgta
    93421 caaaatgatt catggtatta tgtccggcat ccatcctcgt tttcatttgt ttgatatggg
    93481 ttagcaaaaa ttctgtttca tggaacaata acgaaacagg aagatctaaa aaacgaataa
    93541 tcgtttgctc aaatgctctt agattcttct ctatttcttt gtttttttca tcattaatca
    93601 tcaaataatt taactctaat agtcgatttt caattgcttg tttttcttga ttggaaaaag
    93661 aatagggtag ttctgatgat aacttttttg tgagggtctc taccatcgga ataaataatg
    93721 tatacctgtt tgttttttct aaaagttctt ctcttcgaag aatggtcaaa acgagatacc
    93781 gagaaaatcg tatgaagtcc tctcctgaaa caatataatt atatgatata agaacctctt
    93841 ttaatgtctt ttggacagtc ggcatgatat tggaaaaaat tgtactgatt tgttgaggca
    93901 accttgcgtg ttggatcacc gtttctgttc caacaagaga taagaaaatt ctttttgaat
    93961 tttcttcagc aatgattttt agtccttttg tcgacgaaac ttccagttct aatttaggat
    94021 tgcgctcgat ccaacgcaaa atcgttttta tttgtaatga tacggctgtt tttgaaagaa
    94081 agaaaatgtc tgctatcttt tgcatactga catacccttt ttgaaacaat aagtacgtca
    94141 caatagttga agctcggaaa tccatgctgg aatagatttt atgtttcgtc acctcttgta
    94201 tgatttgctg tttagtttca gattcaattg attctaaaaa ataacctgaa cgtttatttg
    94261 actggataat gattttcttc tcgtagatag caagcatatt tttgatttca gtttggatcg
    94321 ttttcttgtt ggtacctaaa gcttcagcta attcttcgct tgttatccaa tgattcttat
    94381 ttcttaatac tacaagaatt tggagttgtc gtttatttaa gtccatttgc ttacacctcc
    94441 tctttgttat aaacatacag gaaaaacctc tcaaatgaca atagtcactt gcagaggttt
    94501 aaaaatcatt tgaagaaaga tctatattca aggtttttac cattagactg gataatttgt
    94561 ttataatatt caaaactatc ttttttcaat ctcctaaagc ttccgctccc atcattttgt
    94621 ctatccacat aaataaagcc atatcgcttc ctcatttccc ctgttcctgc cgatacgata
    94681 tcgattggtc cccaccataa gtaaccaatg atttggcaac catcttttat tgcctcagca
    94741 atttcctgaa gatgtatttt tagatactca caacgttttg gatcgtggat tcgattcaat
    94801 tcatctggtg cttcatctag tccaatgcca ttttcaacta tgaataatgg taattcataa
    94861 cggtctgtca attcattcat gacataacga aaccctagag gatcaattgg ccaactccaa
    94921 ggttcgggag atttttcctt caaaaaggga ttatcgaaac catttgctcc gccagtatct
    94981 acgcgcattt ctgcttcttt tttatagaca gcgctacgat aataactaaa tgcaatataa
    95041 tctgccgtgt tagcttgcaa gcactgttcg tctccatcta acattactgg tgcacagtct
    95101 tcttccttcc atgtcctgta aatataagct ggataatgcc ctcggcacat gacatcggag
    95161 aaaaaccatg aattgcgttt aaattgcagt gaaccaaata cattctctgg atcacagtca
    95221 tatgcataag tcgctaatgc agaaaagcta cacataatac ccatcttagc atttggatcg
    95281 attttcttta ataattgagt agcacgggcg ttcgctagaa acatatgatg acaggcttga
    95341 taaatcactt tttttgttag tgtagcaatg ggttcaagtt tatctctagc agggaatgta
    95401 accaatccag cagctgcata aggcatacga aaagcattat tgatctcatt aaaggtcatc
    95461 caatatttca ctttcccttg gtagcgttca aagacggtct gcgcataaaa ttcaaaaaag
    95521 tcgattaatt ttcgattttg ccacccccca tactctccta ccaatgctaa gggggtttca
    95581 taatgactaa gagtaattac tggctcgata tcatatcgat ttaatgtatt gattagtctg
    95641 tcataaaata cgagaccagc ctcatttggc ttctgttcgt ctcctcttgg aaatattcgt
    95701 gcccatgaga tgcttgttcg aaaagctttt aaacctaact ccttcagtaa acgaatatcc
    95761 tcttcaaatc gatgataaaa atcaatcgct tcatgagaaa gataatggag tgattcgtct
    95821 aaagcaatct cccaaatctt tttttcttca ttccactgaa tactaggatg ctggttcatg
    95881 atcccgataa gcgtatctgt cacattaggt aatttgccgt cttccaacca tgcaccttca
    95941 cattgattag cagctactgc tccgccccat aaaaaatttt ctggaaatat ttcctgatcc
    96001 ataactatct ctcctcgcta tcaacaattt cttacttgaa gtatagctcg attcatcaaa
    96061 acaagatatt ctaactattt cggcagaaga gaagaaaaaa attgaatgct actcttcatt
    96121 tttaatattt atatataaca aatacataag acgatccccg aaagaaaaca ctcgttaacc
    96181 atctaagcaa acgatttatt ttacttccaa cacaaatgct tcataaggtc gtaaatcaac
    96241 tttgccgtct ggtaactgtt tcagaggata atttgacaca ataaccctta aagcttcacg
    96301 tggaacagtg aacgtctgct tttcactgga catattacaa ataacgagcc attgctggtc
    96361 ttcatatatg cgagaatagg caaagacatg ctcaggcgtc ttttccacta attcatagtc
    96421 tccccagacg atgatgtcat gttttctacg caaatcgatc aatttcttgt acatataaaa
    96481 aacagaatct tgatctgcta acgcttcttc tgcattgatt tctttataat ttggattgac
    96541 tcgaagccat ggaattccag tagtaaaccc agcatgttca cgggcgttcc attgcatagg
    96601 cgtcctagca ttgtctcttc ctttcgcatt gattgattcc aagatttcct cttttgtaaa
    96661 tccagaagaa atcctttcgt tatacatatt gattgtctca atatcttttg cttccgcgat
    96721 atcatcgatt gggcaattcg tcatgcctaa ctcttctcct tgatagatat aaggggtgcc
    96781 tttcatcata tggagcaaga tagcaaacat cttggcactt tcttttcgat acacatcgtc
    96841 atttccccaa cgagaaacaa ttcgcggaag atcgtgatta ttccaaaata aactattcca
    96901 tccttcatca cctaaagatg tttgccattt ggataatact tttttcagtt cagagatact
    96961 caagggtttc aaatcccatt tgtctttgcc ttcttgctga tctaatccta tgtgttcgaa
    97021 ttggaagacc atggataatt catttctttt aggattggaa taaagtttag cgatttcggt
    97081 agttgctccc catgtttcgc caacagtcat cagatttttg tcaccaaaag ttgcttgatt
    97141 catttcctga agatactcat gcagtttagg tccattactt gtgatttctt tatccggttc
    97201 tttgccaatc atatcgatca cgtccatacg aaagccccca atacctttat cgatccagaa
    97261 attcatcatt tgataaatct cttggcgaac ctgtttattt ttccaattca aatcaggttg
    97321 acgcttgcta tacaagtgca gaaaatattg ccccgttttt tcatccaact gccaagcaga
    97381 accactgaat attgagcgca atctattagg ctcttttcca ttgaccggat cacgccaaat
    97441 ataatagtcc cgataaggat tttctttatt tttacgggcc tcaatgaacc acggatgttc
    97501 atcagaagta tgattcacca ccagatccat gatgatacgg atatttcttt tctttgcttc
    97561 ttcaatcagt tcttccattt cttccatcgt accgaattct gccatgattg cttgataatt
    97621 actgatatca tacccattgt catcattcgg agactcgtat actggagaaa gccaaattgc
    97681 atcaatacct aaatacgcca gataatccaa cctggaaata atcccccgca aatctccaat
    97741 accatcttga tttgaatctt gaaaacttct tggatagatt tgataaacaa ctgaatggtg
    97801 ccaccatttt tgttccatga ttttcctcct ataaatggat gtttctattt tttgcttaat
    97861 catttatttt agtctctctc actaaaaatt gtaacgcttt caaatagcta ttgcaccttg
    97921 ttatcggtaa cagaataaaa caaaaaaaca gctgaggaaa ttccctcaac tgttttttga
    97981 aaggattgat ttatgcaggg aagaatgctg atttcacaac ttctttataa acggtgttca
    98041 ctcagctgtc ccttggtatt agctcaaaaa acggcaaaat atgaggaact attttttcgt
    98101 ttttttctct aatactcagg ccagaacact gatttcacaa cctctttata aacggtgttc
    98161 actcagctgt ccctcggtat tagctcaaaa aacggcaaaa tataagaaac tattttttcg
    98221 tttttttctc taatactcag gccagaacgc tgatttcaca acctctttat ttcacattca
    98281 atatccacat gaatcccaca aatacaaaga acagaccata catgattgga gatacttctt
    98341 ttcctctttt agctgctaac atggtaattg gatagaagat aaaacctaat gcaatcccat
    98401 ctgaaatact ataagtcaaa ggcatgccga tcaagatcaa gaatgaaggg atcgcaatct
    98461 ctaagtttcc ccattcgatt tgtcgcaaag attgtgccat caatactcct accataatca
    98521 atgctggtgc agttacttgt gaagtaacaa ctgatagtaa tggagaaaag aacaagccta
    98581 acaagaagaa aatccctgta gtaatagctg tgatacctga acgtcctcca acggcgatac
    98641 cagctgatga ttctacaaat gcaccaacag gagaagtacc aaataaggaa cccgcaagca
    98701 tagctgttga atcagaagct aaagctttcc ctacacgagg catcttgttg tctttcatga
    98761 aacctgcttg gtttgctaat ccaactaaag ttcctgctgt atcaaagaaa gtcacaagca
    98821 agaatgtcag cactacgacc cacatttgaa gagaattgat gtcccctaca tgttttaatg
    98881 caactaaaaa tgttggtttc aaacttggtg ctgcggcaac aatttcagaa ggcattggaa
    98941 tcaaacctgt gaccagacct aaaatcgttg tagctgctat cccgatgaag atgccacctg
    99001 gtacacgccg aacaagcaag atagcagtta cgactaatcc aaaaatcgtc aaccaagtag
    99061 aaccaacgtt gagtgatcct aatcctacta atgtagattc attcgaaacg atgatcccac
    99121 cttcgctcag accaaggaaa gcgataaata gaccgatacc gccagaaatc gcatatttca
    99181 aatctgctgg gatcgcatca atgatcattt cccgcagctt gaagattgtg atcaaaataa
    99241 aaatcaaaga agcaacgaat acgccggcta atgctgtttc ccatggaatc cccattccta
    99301 aacaaacaga ataagcaaaa aaagcattga tcccaagagc aggtgccgtt ccaattggat
    99361 aacgggctaa tacccccatt aaaacacagc cgatcgcact ggctaatgca gtcgcagtaa
    99421 acactgctcc ttcatccatt ccagaagcac ctaatacagt tggatttaca aataagatat
    99481 aagccattga gataaatgtt gtaaatcctg ccagtacctc acgttttacc gtggtgttca
    99541 atttttctat ttcgaagtag gaaagtattt tttccttcat cttccatccc cctaaatccg
    99601 aacattataa ataaagtccg ttaaaatttc gatttattaa taaaacaacg tgttttatca
    99661 tatactaaaa caaaacataa gtaaacaaaa aattcggatt ttaagcaaaa tccgaacgtt
    99721 ccatctgatt aaatcccttt atctcaaagt tcatgaacat tcactttgga ttacaagaat
    99781 ttctttattg tgttaataaa gtttcttcat tctagtctca aaaatcaata gtgtgatttg
    99841 attttaccat ttcgtttctg ttcttctttg atgaattctt ttgtatcgac aggattcaga
    99901 ttatttagtc cgccaaaacc tgtatcgacc atttttcccc agccttttgt cttctttttt
    99961 cctgatttga gattctttgc tcgaagcttc tcactatgtt ttgctcgccg atacttcaaa
   100021 taaccttcta atcttcccat tagatccact gtttttcctc ctttttattc aatcagacga
   100081 ctcagctttt cctataacaa aataattgcc ttcagggtca gaaaaattga aagtcaagat
   100141 gccattgtta tctgtgattt ctcctggttc ttccatgttc tcgtagatag tttcaaattc
   100201 atccgtaaaa aatactaaag aaggcggtgg tcctaatacc tctggtgaaa acttctgcac
   100261 aaatactttt gggaatacgc ctaattctaa ttcttttgag atgctgagta caatactctt
   100321 aaattcttct ggcaattcga ttgtttcaga aatttctgca ccaatttttt ctacaaagaa
   100381 tcggcaaatc atctctacgt cattgacata aagcatcaca cgtgtttttt gtatcatcat
   100441 ttgacccttc tttctatttg attttctttc ctgtctataa actgattcca ttatatcacg
   100501 aaagcgcaaa caccttgtgt ttgatactat tcaagaaaaa taaagcaata gtttctagga
   100561 ttgctttcct ccacaaactt tttttacaaa aaaaaaaaac ggcaatgaat gccgctcttc
   100621 ttatttcgat tcttttataa ttctgcttct gattcatctt tggttagtgt gtgtctaaca
   100681 ctagttacgc caaatgtttg atcgattttt tccttcaacg cttcgattgc ctgtgcgcca
   100741 cgtgccgctt gttcagcatt gatggattca atgaccagca ccgctgcttg tgtttcttcc
   100801 gtcagcattg ttctttgggc ttcacgccag ttgagacagc gacagatcgc tccttgttca
   100861 tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg aatctgcacc taaaggcagg
   100921 aatgattcgc caccttgggc ttttcctaaa tgcagatttc ctgcgatctt ttcgatatct
   100981 tctccgccgc aaggtacgcc aaaagacaag gaaatactat tatagatatc tacaagcgga
   101041 ttgattggga aaaattcccg ttcttgattt gcacgtttca gtaaagcttc aatagaagaa
   101101 cgtgcacctt ttttagtctt gaatgtggta aatgcctgac gccactgagc aatgacttcg
   101161 ttttggctga atgtttcttc tgtaaggtaa tttcttgctt cttttgctgc ctcattcaat
   101221 aattgatgat acgtttcttc actttctttt gttacgtggt tatcgatacc atttacggat
   101281 aagatttcga tggttgcttc aggaaatact tcccagaaat tggtatccac tattactttt
   101341 ttcatctgtt cacacctctt gattagaata attgcttgat gaatagatag tctgtttggg
   101401 gatcatctcc catataaaaa acatgttcgc tgtatttgat aaatcctttt ttacgataaa
   101461 aagcgagcgc aacatcgttg tgttcccaaa caccgagcca aatggctgtt ttttgctttt
   101521 cttttgcttt ttcaatagct gtatctagta aaaatgtacc gataccttga tgtttaaatt
   101581 tttttcgtac atagattcgc tcgatttcta aaaaatgatc agccatttcc tcagattgac
   101641 tcgttcctgt atttagtttc aggtaacccg caggctcttg atcgatactc actaggaaaa
   101701 aatcggtttc tttatctttt agctcttctg taagtttttc tagtgcataa gcttgtgtca
   101761 agtaatcagc taaatgctcc ggtgaattat cttttccaaa tgtatctgta aatgtttcga
   101821 tactaatttg ttgtagtaag tctacatctg aaggcgtcat ttttcgaatt tcgtatttat
   101881 tcacggcttc ttcctttcaa tagatccttt tattgccttt tttgacaaaa ttccaatctt
   101941 cgctaacatt cttgcatact ttatttaaaa gatattccaa ttgttttgct tcttcgtcag
   102001 aaagaccatt taatgcgact gcattggagt agttgttttc tcgaatgatg aaaggataga
   102061 tttctgctcc ttttttagtc ggatagagtt tcttgatttt tttattttct ttatcttcca
   102121 aacgttcgat catcccattg gattctaatt tcttgattgc tcgggcagtc gttgtacgat
   102181 ctactttgat catttctgct agtttttctt ggatgattcc aggattttcg caaatacgta
   102241 ctaaataaag atactgtcct cttgttaaat cgacttcttt gaattcgata ttgctaatag
   102301 aatctagcgc tcgggcaatc attccgatgt ctcgaaggat ttcagccatt tcatcccacc
   102361 tttattttgt ttgtaagact agtttacctc tttttgttgc aaatgcaact attttcaata
   102421 aaaaaatcaa gttctttttt aataactagt aaagtatatt cttttcttct tttacgaaaa
   102481 agctcaatca caatagatct ggtttttgtt ttctaaaata agtaactgtt tcttcgttgt
   102541 tcgcttttct gatagctttg gcaactcttc tatactaaaa aatcccatgt tggaagtttc
   102601 attattctca ataaacttgg cctcttcacc gtggatcgca caagcaaaaa caagtttata
   102661 atactgaaaa agctgtggaa tatctttttg tttattcgta tcaaaaactg ctcgcaactg
   102721 agtagtttct actgttaatc ctgtttcttc atagacttct ttacgcacat tttcttcagg
   102781 agacaatcct atttcagcaa atccaccagg aagtgaccat tctttcgtcc gtttatcttc
   102841 gattagtagg accttgccat cttttttgat ataggcacga acatctactt ttggtgttgg
   102901 atgtccttct ccaatcgttg tgagcgcttt tatttcttcg aaagtttctt ttcctatttc
   102961 actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa cgctctttat caaatacatc
   103021 ttttccataa tatagaccag cttgagaaag tgcgagtagt cttttgtatt gagccaactt
   103081 cttgttcatt ctcttccctt cttttttagc aaatgtatga ctatgtaatc aagtatagaa
   103141 gactggttta attacggcaa ataaatataa tgaaatctgc aataaataaa agaatgttaa
   103201 aaaactcgag aacaaaagac attcgacttc tctggggctg tgaataaatg gcgttcaaaa
   103261 gcttgcatct gcggtaataa gccccaccaa acgaaaaata tgacgagcta ttcttgtctg
   103321 gctgttctta ttaattgagg caggacagct ttttcacaac ctccccacta aacggtgttc
   103381 tcctaccaac tcctcggtca caagtcacaa tattcatcaa acatgagaag ctgttttttt
   103441 gaaattgctc cttgtgactc ggagctgaac gacaggctca cgacctctcg gtaaacagcg
   103501 ttcaaaagcc aatttttcga tattaagcca tttctttgtt acttattgtc attgatttct
   103561 ttttctaatt tatccaatag tggagtgtaa tccacttgag tatagtctgt tacatcaaat
   103621 tcatatagtg ttcctaactg gaatttgtca tattttcggt cggcgatgat ctttttgaat
   103681 gcttctttcg taatatgatt ggtccctttc gttcgatctt ccaatacgtc accatagtga
   103741 taatgatcca tgatatagct caaatgacga tctgattcac gatcacgttt gtaccgacgt
   103801 tgacataaca cttcaaagtc tgctgttagg cgaatcgtga tcacctgata tccgtatcta
   103861 tctgctaatt cttggagtcg tgctttttgc ttatcactaa aaggatactc ggacacaatc
   103921 actttctttc ctgcttccat atacaaatca agtgctttgt aatagaaagg ataaactttc
   103981 gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc cgatggattc tgcatagtat
   104041 tccttgattt catcgagcgt gatggcatac atatctggaa atcgttcccg tagtttattc
   104101 ataagatatg tttttcctgt accaggacta ccagccagaa gaatgaaata ctttttcatc
   104161 tcatttattt cctaagttaa ttggactttc caagttcata aacagtccaa tcttatgctt
   104221 gacaatttct tttactgctt catttgctgg aatcacatta tggcgaagag acttgttgat
   104281 ttctgtttca ctaaaggttt ctttagctac tttcgtccag ttgactaaaa gctccgttcc
   104341 aacattgaat ttgcggatcc cgttattgat caattcagga taatcttctt ctttcacacc
   104401 tgttcctcca tggataacta gggggacatc aactactgca tcgatttctt tcagcaaggg
   104461 aatgtttact tctgtttttg atttgaattg tccatgattc gtaccgatag caatagctaa
   104521 tgcatccacg cctgtagctt ctacaaattt cactgcgtct tccggtcttg tatatacctt
   104581 gtcattttca gcgacatgga ttccttcttc tgtaccgccg attgttccaa gttctccttc
   104641 tacggaaaca ccgtgcgcat gggcatattc tactactgct tttgtcttca ggatattttc
   104701 tttgaaaggc agatgggacc catcatacat gacagaagta tatccgctgt cgattgcttc
   104761 tttgatatca tcaaagtctc gggcgtggtc taagtgcaag actgcatcaa ccatttcttc
   104821 ttctgcaata gctgtcatta cattgactaa cacatgcatg ccgatatatt tagcggtatc
   104881 gacacttgtt tgaataatga tcggcgaacc catttctttt gctgcgccta gcatagcagg
   104941 aagcatttct aggttatgcg tattaaaagc tccaactgta aaattcaact cttctgctgt
   105001 ttttgttact tctttcaatg ttgtatacat cttttattgc caccttatct ttttatttgt
   105061 ttcctttgat cgttacttgt tttgcaattt gtcgcatctc atccattttg cccatgtagt
   105121 aatcgatccc ttgatcatca ccagcacgag cagcatctgc acgcttctgg ttatagaggc
   105181 tcatcagttt tttataccca tctccgatcg tctgtttatt ttccaaactc ttttctaaat
   105241 attggatggc ttgatcgttc acatacaatt cagaaaattt aagtccaact tgttcataaa
   105301 gtttcgctaa tttatgctta tcttgggtag tggaaatctc ttgtttcaat tgtgtaatct
   105361 ctgattgaat cttttcggtc gcttctggcg atagggcttt ttcttctttt gccagaactt
   105421 ttttcggttc tttttctttt ttcttaaaaa atccaaacat cattttccct actttcaatt
   105481 aaaatgcttt caaaactggg cttaagatcc aggcatataa gagtgctgcg gctactgtat
   105541 ctacatcggt tgctgtagca ttgatgaatc ccatcgaatt aaagatcgtt actagcaaag
   105601 cgggcaataa tgtaataaag aaaccatgag caataccgcc aatgatcgct cctcggcgtc
   105661 cgccaactgc gttgccaaat atccctgctg tccctccggc aaagaaattg gttagcatac
   105721 caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa catggcaata atcgtaccaa
   105781 tcgttgtcgt aatgaaacct aaaatgacag catttgggct ataaggaaag aaaactggac
   105841 aatctaaggc agggatcgca tcaggaacta atttcatagc tatccctcga aatgccggca
   105901 cgatttcacc taacagtaga cgtacaccag ctagcaatac atacacaccc actacgaatt
   105961 ggatggcttg taaaaaggca aacatgatat agttttgatc tcctgataat tcagaagcga
   106021 atggttcgcc tgcaaataaa acagtgatga tatatagcgg gaccatcacg accatgacag
   106081 acaaataagt atcttgcaga aattcgaaat gtgtcggcaa cttgatatct tcgatcgact
   106141 ttttattttc gcctttctca ccaaaaagct tagcaacacc ggcttcaaat aagtacccga
   106201 tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt gattttacga atgatcggtt
   106261 gcgctactgc cggcatagca atggcgaaac aagctccgat aaaaccaccg accaagatca
   106321 atacgatccc tcgcagaccg gcaaaatagc caaagactgt cgtcatcgtt gccatccata
   106381 aaattgcttg accagttaaa aaaatgtact tccattttgt gaaacgagcc aaaataatat
   106441 tgaatacaaa aatggctaag aacgtcagtg caatatctct acctaaaccc aaatcattca
   106501 ttgcttgacc attgatagat tcaatagaag ggatgatccc ttgcatatga aatccttcag
   106561 taaagatttt cccgaaataa gttaaacttc caacgatgat gctcgaaccg gcactcaaca
   106621 cttgaaatcc taggagtgtc tttaacgtgc cagagatgac ttgtcctgct gatttcttct
   106681 gcagtagtag acccaacata gcaatcaatg caatggtgat cgatgcctga gtcaaaatat
   106741 tttcgatgat aaaattgata acgcccatgt ttttaccctc ttttcttttt gtatttagat
   106801 aactccctta tcttgcagaa ctggggtgat tttttcttca atttcatttt ttgaaacaat
   106861 atttttcaaa tagatcatcg ccgttttagg atcaactgcg aacttttcga actgcgaacg
   106921 aaaattttct gctgtgatga tcacatctgg tttcatggaa actgcggaag aaatatcaca
   106981 atggtccagt ttggcttcta ctcctaattt gttcaaaaca tcctcagcag acatctgtgc
   107041 tgcaaaacta cttcctaaac ctgcaccgca tacgaataaa atgttcaatt tgttcatctt
   107101 tgttctcccc cgtatcattt attatttctc aactactgaa aaaagcagtt gtttgaaatc
   107161 ttcgatattt gtgcattcaa tcaatcgatc caacttctct tcgttgttga tcaattcaat
   107221 tagttctttc atgatgttca gatgcgagta ggagtctact gctgccaaac aaaaaataat
   107281 ctttactgga tccatttcag gattaccgaa atcgattggt tgctcaatcg tagctacgct
   107341 gactcctaat ttattgaccc catcttctgg tcgggcatgg gctagtgcca tgtgtttgcc
   107401 aatcacgata tacggtccgt aatcattcac tgcacgaatc atcgcttcga catagcgctc
   107461 ttcgacaatg ttttctttaa ccaatggtct agcagctagt tcaatcgatt cctcccaagt
   107521 agtggctttt tctttgatca tgatattgct gtccgtcaaa atatctttta acataggctg
   107581 gatctccctt ttgttgattt ctaaattgtt tgtttcgaat aatttttcta acttgccata
   107641 gatgattcga tctactcggc caccactttc tttcatgaca tctattattt gagtgaataa
   107701 ctccgtcgat tcatgactgt taggctctaa ccgctgtagt tcttcatttc ttttcaaaaa
   107761 gtcttctata accaagatat tcgtctcagt taaaatcgga tcgacaacta aaagcggctt
   107821 atttcgataa ttcaattgaa aggtgctgaa aaccagattg acatccaatt tatctactaa
   107881 ttcgatttct tttgaactta aaactgcagt aatctcgatc tgaggaaact tttctttcag
   107941 attctctgct aacagatttc cagtagccat cccatggtta cagacaacga ctgatttata
   108001 aacataattc aagtctcgct tgattacact ggcgatcgtc gaaaagtgga tgacaagaaa
   108061 agctatctcg tcctccagta tcttgccacc aattacttct tcgatcgtag gaacaaaatg
   108121 agtgactgcg cggtagattg ggaaataatt tgttcggatg ttttctttca atggattcat
   108181 gacttggata tgattcttga ttcttacaat cagtgcagcc atgtgcttat agagattttc
   108241 gaataaagct tcttccttta gatggaaagg tacgtgtgtc tcgttctcta caaattggat
   108301 caattggatc gttagtaatt gagcttgtac ccactcgatt gaattggaga tatctctagc
   108361 attgaacgtc tcaatagtga aacgaagata atttctttct acttgcggga cattgtccaa
   108421 ttgaaattcc tcgatcatgt ggtcaataaa tgcagaaaag ctactgtctt ttatttctgt
   108481 atttttccaa ttaatggcag agataaattc atgtttcctg attcgctgga tccagatcaa
   108541 tgtaaaaagc aggatttgtt ttttataaat atcatcttct tgtttcaaca acttattgga
   108601 atagatctcc tgtatttttt tgatttccac caaaggaaaa taatggagaa agattttttg
   108661 agccggtgtt aattgtgcat cttgattcat aaagaagtcg gtcattccca gattctgatt
   108721 gataaaatca tagatcatcg tacggataga tcgttctgaa cctttataaa ccagtccttg
   108781 ctttccataa ctgacgatct ctatcccata actgaccagt gttgctcgta accgtctcat
   108841 atcttcatct aatgtacttt tagagatttg aaattcttct tcttttttgt ttagatggat
   108901 cgggattcgg ctgtaagcaa cggctaaaac tagatcaaaa atacgttcgc gccgattcaa
   108961 aaagccgtct ttcacatctt ttatttcagt ttctaatcga gcttgctttt ccttttccag
   109021 cttcaacaaa aaaactttgt tgcgaattgt acggatctcc ggaagctttt tactgctcaa
   109081 ccagatattc gcttcaagaa cttcctgacg gatcgtccgc tgactgacat tgaactcact
   109141 tgctagatgt tttgctttta ctggatattg ggctgtcatg attctgtgaa gtatttcaat
   109201 tgttcttgtt ttcatagaaa tgatctcctt ctgatttcaa gtatatggtt ccgcttacat
   109261 aataaaaagt agatatttct gccacttgaa gtggaaagaa agtaagcaaa gcaaacaaaa
   109321 aataagccat atgctttttc atctcctcaa cgaaaaagac atacgcctat tattacaaaa
   109381 attttgccca tctatacaaa aaagaggttg tgaaaaagct gtcctgcatc aagtaataag
   109441 aacaactaaa ctaaaatagt gcttcctatt tttcgtttgg ttgttcttat tatcgcagat
   109501 gcaagctttt aaacaccatt tagtggagag gttgtgacag agatgttcag ccttgagcga
   109561 taagaagcga ttttgaaaaa tcgcttccca tattttacaa aatcgtgcct tattgccgat
   109621 aggctatctc tggcacactg tttattcaga aaaaggagct gcgacaaggc ttttgtcaca
   109681 actccgttca taaatatttc ctgtcaatcc agcataatcg gctgaataaa atcggcttgc
   109741 catctttttt ctttctcaga aaaatcaaaa taccatatct gagaaaaata ctgtcgttgt
   109801 gtcttacttc ctgagatcaa tcgcccatct tttcgatcga ctgaataatc acagcatctg
   109861 aaatcaattc ggatggcaaa actattttcg tggatctgtc gataatttcc tacttcctga
   109921 atagttattt ttttagtatg atttcttaca ccgtctgctt tgtttttttg cagaactttc
   109981 tgatgttcgg caaacagctt gtctgtataa cagcttctgg ctttttcagg agtttcttct
   110041 tcccaagcgg attggatctt catgaatatc ttttggattt ccagaaactg tgctttcttt
   110101 tctttagccg ttcctgacat gcgggacaat atctccgctt tcagcctttt cttttgtctt
   110161 ttattcttga cgatagaaaa agcagaaacc cctcctactg acaaaacagc taatgcaaga
   110221 aatcccgttt gctcataact agaaggacct gtacctggac cataataccc ataagaatct
   110281 ctgccgtaag aacgactgcc aaaataactg cccccatatg aacgaccacc aaatgaacct
   110341 ctgcccgaac ttcgaccgct agatgtacct ccaccatgac cacccgcgac agcgaatcct
   110401 tgggtcggca gagcaaacaa acataggccc actaacaaaa tgattgctaa ataattgatt
   110461 tttttcattg tcttcctcgt tatcttttat tacaaaaaac tatttttatg atagccttgc
   110521 taaaaggaag agtcaataac cagatgcata aactgttttt ttagcaattt tgtcttattt
   110581 agtcattgag taacatcgga caaatgtatg tgtcggcagt ccataattcc tctatcttca
   110641 gcatgaacaa gcttgcagac aagagatctg cgcttcctcc aggagagatt tggttttcct
   110701 gacaaaagtg caacagtgct gtaaatggac gatttggtaa agcactttga ctagcagcat
   110761 gagcaagttt ttgcatttcc actaacgttt tctgatcact gcgatgcaat acgcatgtgt
   110821 catctagcga actcatcaaa actaacaaca tatgcatttg tttctgtaca tatgaatcat
   110881 tatctagctc cttagctgct tggattgcaa gcctgatatg cggataccct aatatcgctt
   110941 cttcatatgc accatttacg ccatattttt gcttcaccct atgaccatga gtggtttttt
   111001 tatgacgata ttttgtatca ggaaaagcag caagcttgct gacatcatca agtattttcg
   111061 ataaagaaaa aggctgttcc atactgattt tttgtgcaat gacactgatc aatagcccca
   111121 ttgcccaaat cgctccttta tgggtattga tgccatttgt agcaatcagc attgcctttt
   111181 ccgcttttcg cccaatctca gcaattcttt ctcttaactc ctgatcaata gcatgatgcc
   111241 atgctatttg agccatttct tcaaaaaaag gagttagcgt cttagcagac ttaagaaata
   111301 aagcatagtc catatcggaa tgtgcacccg catccagtgc atccactaat ccaggttttg
   111361 gacttaatgt tacttctgcg atcaatgctt cctctaccaa cgcagcgagt tgctgagtca
   111421 ctgctttttt tcgttcgtca tttatcatga cactcactcc ttcttcctac tattacttgc
   111481 tgaaaccttt tttgatagct acccaaatga tatgaagtaa ccagcttaaa gcaaatgcac
   111541 aacttgccgt cattagataa gctacaagaa tcatgactcc tgaaggtaac tgcagccaac
   111601 tatctttaaa caataataac agtacttgga aaacaaatac attggctaaa tacgtacgat
   111661 aagcataaac agacaaccat ttgaacaatg gcaattttgg cgaatcgttt acaatcattt
   111721 tggaagcgcc tatgaagaca gcaaagatga tgactaaact gtataaactt tggatcgtat
   111781 tcaagtaagg tgcattcgca aagctcaagt ctcctggatg tgcgagcaat gaacggacag
   111841 aaaagaacgc gataactaag gcaacaggta agaaaagata acgtactctg tccaaatatt
   111901 gatagacttt ttcgtgataa acaaatgcgg ctaccccata aatcatgaaa ctagcaacaa
   111961 accgatctaa taagtaccag ctgtcatgat aaggcccagt caatacttgt gtttgataga
   112021 acagatacca tgcgacatat aaaatcgttg aaccaatcaa tactggccat acatattttt
   112081 tattagcaaa tactttgtaa ccgagccaaa caaaaaacgg catgaacaat tggatctgca
   112141 gcatcataac ggtataccat aaatgaggcg ctccatcacc tgtgacatat ttcagtaaaa
   112201 agcttgcagt atccgtatac ggagtttgtt gttggactgc tggaaatagc caaagataag
   112261 ccgtcgtcca tagaagatac ggaacgacta gttcaaaaaa cttttctttc aaaaattccc
   112321 aataagacaa atgctgactt gtttttacca tattataaac aattgcaaaa ataaacattg
   112381 gtgctgtgta tttaacgatg acgtaaaagg taccaagaaa agctgtattt gttgcgctgt
   112441 ggctgtttgc caaagcaaag ctcaatatcg tttgcatcat aacagccgtt acagctgata
   112501 ctttctggaa gtcacttacg ttgattttga tttttttgtt ttcaaacatc tctttctctc
   112561 tctttttctt tattaccaaa gttctttggt taatttaggt ccttcgactg ttttcaatag
   112621 aatttttttc tctggctctc tcaaatactc ttttagtgaa aaaccgcctt gccgagtcac
   112681 tacttgggta tcgaattgct caaaaaaagc aggatgcgat tgaattacct gaattggcaa
   112741 ttcaatcggt gaatttgcgt acagcagcaa atcaaaatca ctggtttctt ttactgccgg
   112801 aatcccagtc gataattcaa atcctaagct gccgccgatt ccccatttac atcctgataa
   112861 tatgtttcta gcagcatgaa attgctgata aacaggataa tccatgattt tctcttgtct
   112921 atacgattct tgttcgatga tgtcccacgg atgaatgact tgtttgacgg catgttttga
   112981 gatttctgtt gaccatctct gattgcgggc aggtccacgt aaaccaatcg gtagtatttc
   113041 tgcgtgatcc gtcgacgcac gacgaactgt tccgaacatc ttttcagtta gaacgaccca
   113101 ttcaggcaag gtgaaccctt ctatttcatg tttatcaaaa aggacaatat catgtgcttg
   113161 aatcattttt tatgcatccc attcttcgtc cattttggca cggactttat ttgtttcgac
   113221 acgtccgaat gttttggctg tttcgtttgt gtatcgattt gtcagcatcg tgtcatttgt
   113281 attgcggaca tcttgaatgg cttcattgat tgcttcgatg actttgctga cattttgttc
   113341 tgaagcagct tggtcggtga tatcttctag gaaatgatag atcgctccta gttttgtata
   113401 attattgata tcgtaagcga tagctggaac tttttcagca gctgcttcga tttcagcaac
   113461 cgaacgtttt gtcacacgtg cagcactttc tttagacatc gcttggacgg taatttcttt
   113521 attgtttaaa gcaatcaagc ggcttgattg taatccatgt gctaaaaatg cacctgaaat
   113581 agcatttcct gcaatcaatc caataactgg atgtccagct tgacggagtt ttgcataagc
   113641 agcagcacta ttagccaaag ccacatggat accgatcaat tcttcgttat agccgtatgc
   113701 ttggcttggt acatcgatca caacgatgat tggccgtttc acttttttgt ctttatcttc
   113761 ttcgtaaacg tgatccaaaa tttgtcccat gcggaaacct tcaactaaac caacttcacc
   113821 gtttcgtaca cggtacatcg ggtttttagg atcaggtacg attgatgtca cgatggcttc
   113881 ttctatgaat ttacttgatt taccataata cacagtacta atagaagaag ttggattttt
   113941 catgccagtt agtgccgcaa accaatcgta accaacactt gctgcagctg gttcatttcc
   114001 ttctgctact tctggtaagt caattgattt tgcttgatgg ttagcaattg cttcattgta
   114061 atcgtcaatg gccattggtt ttgaaagatc taaagaatca agtaatgata aataaaatgc
   114121 tgagctttca ctgcgatgcg tgtcttttcg ttcgtccatt gctgcgatga cagcagcttt
   114181 gattgcttct acactatcag tcactaattc atcaatgatt tttgattcta cccgttgacg
   114241 agatcctaat gtattccaaa tcaagtcttt gtcactagaa tcaaattctc gaacgcctgc
   114301 ttcttgttca ataacttctg gtccattcaa accgactctc gctttttttg ttgcgattaa
   114361 ataactcatt aatgctgaag taatcgacat accgccaaat gatcctacac gtcctggaat
   114421 caaaccgatg actggtacat attgttttag agcaatgatt acatttccga tttctgaaat
   114481 agataacagt ccgtagtttg cttcttgcaa acgaacacca cctgtatcta gtacaatgac
   114541 tggaaagatc tcatttcctt ttttattttc ttctaacaca tgttcaagtg cagcaacgat
   114601 ttttgcaccg gaaacttcac cgataccgcc accttggaat tttccttcca tagcgattac
   114661 tactgcttgt ttgccattga tcgtgccacg gctgacaacg atcccgtcat cactttcagg
   114721 gacgattcct tgtgctggta aacttggcgc gatgatttga tcgaatggat caatcaattc
   114781 acgtccattg tcaagtagag cgttcactcg ttctctggcg tttaattcta caaaactatt
   114841 tttcatctga aagttcctcc attgcttgcg tcaatcgtag gtacacaact cctggtgtag
   114901 caccgaagtc attgatcacg atatctgctg aaattggata acgatcaaaa aatctcgtta
   114961 atacattgtt ccatacttcg ccgaagccat cgcttcctgt acaaattttt acagtagatt
   115021 ctgttttttc tgttggaaac atcaagattt ccaaatctcc tgaaccgacc actcctacat
   115081 ggattttctt attgatcggc tgtttcgttg gatatttata agctaattgt tccatggatc
   115141 tctccccttt ttgtaaaaca gagcatacac gttctgctta ttcgtctttc ttcttccatc
   115201 tgggtaaatg gcgacaaaag gtttttctcg ccaattttat gaccaagttc tgaatttcat
   115261 tggtggttca tacaggccat ctgaccattc gatcaaatca tcgatggttt gtgcagctaa
   115321 taatgaacgt ttcgcttcac tacgtttgat gcctagatct tctggtaatt tcacgatgcc
   115381 ggctgcacgc aagctatcta gtgattcttt cgtgctagtc attccaagag gtgtaacacc
   115441 gccaattgct gcaattgctg cttgtcgttc ttcttttgtt tttgctttgt acaaataagc
   115501 aattccttct tctgtcacga tatgtgtagt atcttcgcta taaatcatca ctggtgcatt
   115561 ggctaagcct gcttgttttt gaacagctag tgcatctaat tcttcgacaa agactggttt
   115621 tttatttgaa ccatatgttt caaccatttg aacaactaat ttttggcctt tccctaatgg
   115681 atcatcattg tcgcgaagtg attgccatgc tggtgtagaa tgacgacgac cgccaggatt
   115741 atgtcccatg ttaggcgcac cgccaaaacc agataaacgt ccttttgtta cggtagaaga
   115801 gtttccttcg taatctaatt gcaaggttga accgataaac atatcgatgg catattgtcc
   115861 tgcagcttgt gataatgttc ggttactgcg catcgtgccg tctttaccga caaaaaagac
   115921 atctgggcga gcagcaatat atttttccat accaacttcg ccaccaaaac tatggatgct
   115981 ttcaacccaa cctgattcga tggctggaat catcgttgga tgtgggttca atacccagtt
   116041 cttcgcgatt ttccctttta accctagtga ttcaccataa gttggcagta acaattcgat
   116101 agctgctgta ttgaatccaa taccgtgatt caaagattgt acgccgtgtt ctgcgtagat
   116161 tcctttgatt gccatcattg ccattagaat ttgcaattct gtgatgtttt gaggatctcg
   116221 tgtgaataaa gcttctaatt gataaggttt atctgctttc acgacaacgt ctacccagtc
   116281 accagggata tctacacgtg gtaaagaatc gacaacttcg ttgacttgaa cgatcacgat
   116341 accatctttg aaagctgcag cttcgatgat tgttggtgtt tcttccgtat tgaaacctgt
   116401 gtacaagttg ccgtctttat ctgctttatc tgcagctact aaaacaacat ttggaatcaa
   116461 atcgatgaat aagcgtccat aaagttccaa ataagtatgg atatcaccta atttcattgt
   116521 gccgtcttca atcatttggg cgacacgcaa gctttgtgca ccagcataag agaaatcgat
   116581 cttgcttgcg attccttttt caaaaatatt caaatgttct ggtcgtgaga tactagacat
   116641 gatcaaatgc agatcattca ctttttctgc atctactttt tcaagacttt ctgaaagaaa
   116701 acttgcttgt ttttgattgt cgccttctaa tacaactttg tcgccgggag caatcagttt
   116761 ttccattact tctacgattt tttcagtttc tacatacttg ccattgagca agttgctgat
   116821 tttttccaat cgctgcgctt ttttttcgcg tttagaagcc cagttgcggt ttggtttttc
   116881 cataattagt catctccatt tttgatatag aaacgtggcg tcatcaatac catgttggtc
   116941 tagattgatc gtacggatcc ctttatctac accaaatttt gtatgaatca gctttgtcaa
   117001 agtattgccg gggggaaatt caatcgtcag atccattcct aattcttttg ccaagtccat
   117061 catttggttc cactgcacag ggaaagctag gttttccaac aaatctttac gaatctcttc
   117121 tgcgtcctga gtggctcttc catccgtatt ttttatatac aaacatctag catcagatag
   117181 atggacagac tgcatatacg gcttgaattt cttgaccgta tcattcatca agagacagtg
   117241 agatggcaca gggactttca gcagcttcgc tgtttgcgct tggtgccgtt tggcttctgc
   117301 caacgtaacg gataaacctt cgatactccc agataacgta tgttgcatcg gacaattttc
   117361 atttgacaga taaactggat ggtcaggatc aaatgttttt gctacaattt cctcagcttc
   117421 gcttctcgtc acacctacta ctacgcccat tgcataaccg cttggataag cttctttcat
   117481 taagactgcg cggtgataga ctagttccgc tgcattctca aatctcaaag atcgacaagc
   117541 aacagctgca caaaaagcac caatcgaatg tcctgctgca atatcaggct gaataccgtt
   117601 tttttccatt tcatctaaat aaaatactgc ttttgtcagt aatgctagct ggataaaaac
   117661 cgtatcttga tagttttctt ctttatcaac taaccgatac cccgtcacat tttctaaacg
   117721 ttccatgtac atttcaggga tatccgctaa catccctaac ttctgactgc cttgtccagg
   117781 aaataagaaa cctgtactca tgagcctcgc ctcctcagca cttacttttt ccactgctat
   117841 cttagtcaat ttctgctata ataaaaaatg ccaaaaaaag aaaaaaccat aacaaaaagg
   117901 tatggatggg atggataatt atgaaattgc ttcatctgca gtattttaaa aaagtattcg
   117961 aaacaaaaaa tgttacccaa gcagccaaag aattatttat ttctcaacct gccttgagcc
   118021 gtgcgatcaa acatttggaa aacgaattag gtgtcccttt gttttaccat agcggcagaa
   118081 acattgagac gaccgtttat gcagaagaat tttatccata tgcagtcaag acattagaca
   118141 cattagaaga aggaatcaaa ttattgtctt cggtcaatga gaagatcgtt acttccgtca
   118201 tattgtattt agaggtagcc tctgtttcta ttccgaactt ggtccgaatt tttatggaaa
   118261 agcatcctga tatccaatta acgatcatgc aacatcattt accagatgat attaccgatc
   118321 ctgtactgta catcacttcg gagatgaagc ctggcatgac caatattcct atcatgaaag
   118381 aacctgttta tgtcgccatt cctaagaaac atcctcttgc taaaaaagaa catctgcaat
   118441 tagaagatat ccaacgcacc cccatcttga tgctgtcaaa gagcaacgcc ttccgtcata
   118501 cactggatgc agcacttgaa gcgaaaagta tcgaattgac gatcagttcg acgacagatg
   118561 atcctgcgac attacgttct attgtcaagc aaggattagc tgttagcttt ttcccaaaag
   118621 tttcttggtc ttacgataaa aatgatcctt tcgtcttgcg ggaaatcaaa gatttgccct
   118681 tgacacgaac aatttattta tcttctagct tcacagaaga tcatcctttg atcaaaatga
   118741 ttgcaaaaac gatgcgggaa ttttatttag gaaaataaaa aaaaaagagc tgggacaaaa
   118801 ttcttgtcgc agctcttttt tcgaacaaac ggtgttccag aagtaatttc ttagaaaata
   118861 agccgaaatt tcccaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
   118921 gctaaacatt tctgtcacaa cctcttctct attgtcctag acattcattg cgttgattta
   118981 aaacttccat caatcaaatc tgctagttca tctagctttt ctattttacg tagatcaata
   119041 gagatccaat gttctttatt catgtgatag gctggaaaat acccctcttt tcctcgcaaa
   119101 attccgccaa gttcaggatc gaccttcaaa tcaagaatat tgatgatcct atggtcactt
   119161 gcatcatcat agattttttc ttctggaaca gacatcagga ccccaaacca ttttttgctt
   119221 ttttgatgtc tgaatacgca ataatcagga aattttttaa aaatatattc tggagacaaa
   119281 ttgtatgttt cattgatgtg atcgattagt tcttttttcg ttagcatctg cttccatctc
   119341 tttcttattg attcgcttta ttcaaagata ccacgtaaga atagaaaaat gaatacaagt
   119401 agttgctaat caaatacttc gatatttttc ttttttatca actcttaaat gttcaatccg
   119461 cctgtgttgg tcttgctacc atctactatt aaaatgttta ttattgtttg cccacctatt
   119521 ttttgatttt agtggtatca tttttcaagt tcatgatgaa attcttatca tcagtaaatg
   119581 ctccagaaaa ataaacaatg attgaaaaat cagttgaaac ttgaccaccg tttattttct
   119641 ccgtattctt agaatagaag ggagtctgat tgatgtattc actaatgaaa aaaatcatta
   119701 ccgaaaaaga tattcgacgt catgtttctt tagtagaaca attgctgaat catacaaaga
   119761 taaccgtaaa tgaattagct gaaatcatag ggacaaccga acgaacgatt ttttctgacc
   119821 ttcaatctat tcgctctcag ctgcccgaag gctgggacat catcagcgat caagcaggaa
   119881 tcagtttgca aaaccagcaa aatttattaa caaatgacct ttgggagatt tttttcaaac
   119941 aatcagtcag tgtcgaactg ctgaaaaatc tgctttttac aaaaaaagtt gctgtccctg
   120001 attttctagc cgaccatggg ctttcttatg ggacattgaa aagacatgtg actaaaatca
   120061 atcagcgttt agcaagttac gacttgcaga tcgatttgac gaaatataca gcttgtattc
   120121 ttggaaaaga gcgtgcgatt cgtacttttt atcatcgatt gctgattcct ttcactcata
   120181 acaactattt tttcgaggat tattcgatcc atgaatccca ttattttcaa tttttaagaa
   120241 acctcagtca aactgaacta gcggttgaaa cagaagagat tttcggaaca tgttggttct
   120301 ttatcaatac gatccgtata aaagcgaatt gccgattaga ttcttctatc cataccaaca
   120361 gcacactctc ctccctgtat gactctgcat tgaaaaaatt gtatttaacg gaaggtattt
   120421 atcttaaaga cactgagctt tcttttgctt ctttctgctt tctggaaagt tggaattaca
   120481 acaataacta tggacaagaa accgctcgct gcctgcatca ttctccattt ttagaggtcc
   120541 tcgaaacgtt tgtagaggaa ctagcttcag agctgtctct tgatcaacta aaaaaaacat
   120601 ctctgactga taacttggct ctcctcatat taaaatatca tgaatcgccg atattgattg
   120661 aagcattgga ccgtcaatac catcgttttt tagaaacata tgatcagcaa tatgcacact
   120721 tgtatcaaca gaaagagaat ttactgaacg atctaaaaaa agaaatagaa atcaatgaac
   120781 caaattactt tctccaactc ttgtctctac tgatccaaca aacgattttt tctatcaaac
   120841 cgaatttgtt caatgtctat tttattttcc aaggagaacc ttcatggaag gcgttcttgc
   120901 agcaggaatt aaaagattac ttaggaaaac gtgtctgctt cttacctatc gaactaaccg
   120961 atctttccac tatttctttt gaaaaaacag atatcttgat ttccaatttc cctctagatt
   121021 ctctagatat ccctattgta tacatttctt ctattccaac gaaaaatgag ctcaatcgtt
   121081 tgactgaact cactttcaaa acttttttat agtaacggct agcgactgta ttctctagct
   121141 gttttttctt ttttgcgaaa cagtttgttc atgatccctt tttctatttc tacaactaag
   121201 aatagaagaa tcacatttgc tccaatcaat aactgttgtg tcatcgttaa acttactgta
   121261 ccgatcagct gctggccgac tggtagaaaa ataaccatcc cttgcaataa agcaaggata
   121321 cctaatgaaa gaaaaagcgc tttgttttgc aaaagacctt ggttcaatga cggcttggac
   121381 aactctctgc aattgatcat gtaaacagct tgagctaaga cgatattttg cagaagaatg
   121441 gtttgctgta agctttgccc ttcaaactgc atagccaata aataggcagg aaccatgatc
   121501 agtagggaga catagatgat ccgaaacaaa tgataaccag ataggattcc ttgctttgga
   121561 tctcttggtg ggcgcttcat gatttctgga tctggcgact cgaaccctag tgcataagat
   121621 aaagtgattg tcgttaccat attgacccat aaaatctgta ctggggacaa aggtagcggg
   121681 cgattcagca taagtgccca aatcaagatc aatccttgag ctaatgcagt tggcaagaag
   121741 aaattgatgg ttttttgcaa attatccaaa atccgccggc cctcttttac ggcttttgca
   121801 atcgtatgga aattatcatc tcctaaaacc atatcagctg cctgtttgct tacttcacta
   121861 cctttgattc ccatagcaat tcctacatcg gatcttttca aagcaggtgc atcatttacg
   121921 ccgtctccgg tcattccgac gatttctcca tttttctgca aagctttaac aattcgcagt
   121981 ttatgttctg gtgtcgttcg agcaaagaca tcgactattg gcacttgctg aatcaactct
   122041 tcatcagaca taagatccaa atcgatccct tctaaaactt tggcagtatg ttttaagcca
   122101 atttgttccg caatcgcttt tgctgtgtct ttgtgatccc ctgtaatcat tttcactgag
   122161 atccctgctt gttggcattc ctttacagct ttgactgcac tttcttttgg cggatcgatc
   122221 aatccggcga tccctgcaaa agttaattgg gttaaagtct catgcgtgag ttcctgtttc
   122281 gaatctactt ttttataagc aaatcctaaa acacgctgac cttttctcgc aaattctgca
   122341 gctgtctgac tccatgcttc ttgttctgca gaagaaagag ttgatttagc aaataatact
   122401 tctggtgcac ctttgacgta aatcaccgct cctttttcct ccgcatgcat cgttgccata
   122461 tatttgtatt cagaactgaa cggaatcttt gcttctattt ttttcaaagg tagattggct
   122521 gtttctgtgt gtcgaatcag cgcaacttct gtcggattgc cacttaaatt ttctgttttc
   122581 tgttcttctt ttgtttttaa ttcctgacag tttttcataa tggacaacac gcaggcttct
   122641 tcttttgcag ctacatccac aactgtcatt tcattttttg tcaatgttcc tgtcttatct
   122701 gaacagatca ctgtcataga acctaatgtt tctaccgaag gaagtccttt gatgatcgcc
   122761 ttttcttttg ccatttcatg tactccaacg gatagaatca tggtcaaaac agctggcaat
   122821 ccttcgggta ccattgacac caccaaagca atcgtagccg aaagaaggat atgccaatcc
   122881 ataccatatc gaaatgtcgt aaaaataact aagaataggc tcaaacaaag aatgccttga
   122941 aaaatttgtt tgtttaatcg gttgattttt ttaatcagag gcgtcgtttg ttgttcgacc
   123001 gattgcaatg cttgattgat tttaccgatt tctgtcgtgt ttcctgtttc tacaacgaca
   123061 ccgactgcag aaccagattg tacaagcgtt cctgaaaaag ccatattttt ctggtcgccg
   123121 atcgattctt cttctgtcaa aacggcatga cttttttcag atgcttctga ttctcccgtc
   123181 aaaatcgatt cttccactaa taaatcatgt gcttcgatta atcggatatc tgctggaacg
   123241 acatctccgg cacgtaagac aatgacatct ccttttacca gttctttcgc agggattttt
   123301 tcttgcatcc cgtttgatag tactatcgct tcttgtccca tcagctgctt caaaccattc
   123361 aatgattctt ccgcttttct ttcttgccag taactaacga gtccattgac gatcactacg
   123421 aataaaataa tacttccttc aatatattca ctagaagcaa atttcaaaaa agaggcaatg
   123481 atcaacacga tcatcagcag atcagtaaaa tgctttgcta tttttttcca tcgttttgtc
   123541 tgctgccttg cttttatttc attatatcct tgatcagtca ggcgtttctg tcgttcttct
   123601 tgcgacaagc cttctgttga tgtttgatag tttttcaata catcttctac cgtcaatctg
   123661 taccagttca tcctatcccc tcctgtttaa ttgatactgt tattatacgc agggaagttt
   123721 tttcaggcgt atcgattatt tcaggggggt ctgaaataat tcgttttgca aaatgtatct
   123781 gggcctaact gatatttcta ttgcttattc ttttatatac aaaatttaag aatacaaacc
   123841 agataaccaa taaaaaagga ataaagcgtg tcgtgctttc gaataacaag ctgaaagcaa
   123901 ttgaagtaaa aaacaccaac aaagcaagat ctttatatct ttgtgtagtg ttccgtttct
   123961 tttctttaat aaattgaaca tgtgcacaca agatcgaaga ccacacaaat agaaaacaac
   124021 tcgttgtcat gcctgccaaa agctgaaaaa acaatcgact atcagctaca aaaaaatgta
   124081 gacaaagacc ggcaaaaaat aacattcctg taattaaaat accgtgtaaa ggtacgcctt
   124141 tcttagaaag cgcacaaaac caatggggca aacttttttc ttttgctgtt tgatataaaa
   124201 tcctgctagt actgtagact gcactatttg ctgaggacaa agaagcaacc aaaatcatta
   124261 gattgacaat tgctgctccg ccttggcaat ggatcacttg cagcatagtc actaaaggac
   124321 tttcttttaa atctaaacaa tgccatggaa caacaaataa aatcgacaaa atcgttccta
   124381 tatagaaaaa gagaatacgc caaggcagac agttgattgc ttttttcaaa ttcttttgcg
   124441 gatcacttgt ctcgccaacg gttaagccga tcatttcaat tccagcaaaa ctgaataaaa
   124501 ccataggaaa tgagactacc attccagcaa agccaaacgg tagtaattca tcgatctgtc
   124561 caaaattttc tttgattccg atagactggg tatgaaaatc tgagacactc aatcctatac
   124621 ccaataagat aaaaaggaaa atccccaaga tcttgatgat tgagaaaaaa gattccaatt
   124681 caccaaacca cttgactgca acaaggttga ctgccattaa gatcattagt gcgctacctc
   124741 cgcttatcaa agctggtaca tgtacaaacc agaaatggat atacaatcct attgctgtta
   124801 attccgcaag tccagctcca agccagcaaa gccaataagt ccaattgaca aaaaatgccc
   124861 actttttgcc taaataatag tcaacgaaat cactgataga gttaaatgta ctatttgcta
   124921 aaaataaatc acccatggcc cgcatcaaac cataaatagc caaaccgcat atcaaataaa
   124981 cgagaataac agctggccct gctgatgcaa ttgcctttgc tgaacctaaa aataatcctg
   125041 ttccaattgc gccacctaat gcgattaact ggatatttcg attagttaga gtccgtttca
   125101 ttgccggttt ttccatcaag ttcacctttt tctttttcaa gcagcatggc gacttcctgt
   125161 tcccaagaag gtttctttat tttttcaata cagagtggta ctacaaacaa aatgacactg
   125221 atggctgtga ctgcaattag attgatccat gttccagctt tcatcgtcag tccgacagaa
   125281 aatccgattg ccgcaaataa aacaataacg acagtccaaa ctccaagatt gctctttttc
   125341 tctttttttc caattctaaa tggtcgattc aactttgcat gtgtataacg caatctcaaa
   125401 actgcgatcc ccatgatgac atagacgata cagtagataa cagtagttga atttacgagc
   125461 atcaaaaatg cttgattgac gccaggaatc agcaaataaa aaagtgcaaa gattgagata
   125521 atgacagact gagtcaaaat aacggatttg gatacgtcaa attgattcgt cttccaaaaa
   125581 ttgaattttg gtggatacgc accttttcta gcactttctg tcactgtctt tgctggtcct
   125641 gaggcccaag cagataattg gactgctaca ccaatgaaga caagtaaact aaacagattc
   125701 acaataagat gtggcaaacc aagaatttgg caataaatcg aaatagattg cgcgatatta
   125761 ttcaattcca tttgtccttt tggtacgaca tttgctacaa ctaaagcatt caaaatattg
   125821 acgaaaaata taaaaattaa cgcggcaaat actccgcgaa tatacgtttt aactggattt
   125881 tccaatcgag tgatatacac agaggacatt tcgataccag taaaaataaa catgatcggc
   125941 gcaaaataaa caaatgagga tgcagtcgta gtatctggta ttaatttgtc ccatgaaaaa
   126001 ctgcctaatg ttccggttgg tacgatccca actttgatcc acgcagcaaa ccctaataag
   126061 agcatcatcg tcaaaggcac gtacaatcct aaccaaacac cgacttttcc gccgattttt
   126121 gccatatcaa atttcaaatt caaaagagtg atgatccaat aaacgactaa aatgacaact
   126181 aatgtaaatt tgctgttcaa accaagcggc acattatcga taatattacc aaacaacgga
   126241 gcgagtgctg aagcgaccat caccatccca ggaaacattt ggacccataa cagccatgag
   126301 acaacgaacc cccatttttt tcctagagca ttcgataccc aaagttctgg accacctttt
   126361 tggggaaaca ttccagcaaa ttcaccagag atcaatgaga ttggaaaagc gtacaataat
   126421 actgcaacca gcatgtaaaa aatcatcgtc cagctcgttg ctgctacatc tggaatattt
   126481 cgtacacttg ctacaagggc gcaggtcatt ccgataaagg tcatggtcgt gatttgcttt
   126541 gatgaaccag tatctttcat ctttattcct tctttcaata gcgacatatg tttttgtttt
   126601 cttttatttt tgttcaagaa cagaaatgac aaggtttcat cgattcagta caaaacccag
   126661 tatcaccgaa acatccattg aacgatctta gtgaactggg tttgatacat gaaacgaacg
   126721 atccaactta tagaacgttt tataaaaaag aatatcttgg cgaggaatat atgaaaaaca
   126781 gggggaaata caattgtttt gatgaagcaa ataattgtct gttctccata tgtctcttgt
   126841 tattctttca cacaaaaatc agttctattg gatgatttcg tttagtttct tttccattgc
   126901 tttggcgatt ttttttgtat aaaaattgaa aattcgatca tcattcaaat aaggagtcat
   126961 gatagccgca cgtagcagag tgattttctg ttcttttttc cattcttctt tcgttagacc
   127021 cattctttca acaaaacgaa tcggagaatc accgtaatct tcttgtgtaa atgtagtatg
   127081 agaagtaata aaccgttcac cataaacatc gccatccata taagaagacc gatcgaacat
   127141 tttttcattt aattcattga tagcgttcaa atctgtacag ccttgttctt tgaataccca
   127201 attgaccata ttaaaatcag gatgattcaa tggatagact tcgattgttt ttcctttaac
   127261 agtaaaagtc agatgatcga gaaattctct gaatctttga gctgcctcga ttgaagcccc
   127321 aatcaattga ccatatccgg tcacattcaa tggcaataca cgatgtgctg tccagactgc
   127381 ggcggcggtt gctccagctt ttgatccttc caaaatataa gctcctaaca tatctggagc
   127441 ctttactgat ttttcaaaca catatggcgc gaaataagaa atgatatttc tcatattttt
   127501 atgtttgatt acgattcctc cagcagcata agggacatag cccatcttat gaggatctat
   127561 cgtgacagaa tccgcttctg aaatagctct gaacccttca tatacctctt tgtcaatcgt
   127621 tacgcagtgg tggaaaacat gatgttcttc aaagaattca gctaaggaag catacggcac
   127681 aaattctcct gcttcgttta gaaacagtga acgcgcatag ccgccatatg cggcatcaac
   127741 atgtaaatag aaatagatcc cttcatcttt taacctttct cttaattgga cgattttatc
   127801 tacactgtct acttgacctt cttctgtcgt tcctacgaca gcaaccacac ctagaattgg
   127861 gattttttgt ccagctaatt cacgaattgt tttttccaaa gcattaatat ccattcgata
   127921 atcctcttga actgggatag caaccatctg atctaagccg actccgcaaa tatctaacgc
   127981 cttcatccaa gaatagtgtt ttgtttgagg gaccagccat ttccctaatc tttggatatt
   128041 ttttccgcta cgggaagaag ctgctttgac ctcatccatt tcttcgtccg taaagctttc
   128101 ggtcatttcc aaaatttctt caacagataa attcaaaagt tcccactcag acattttttt
   128161 cactttttca ggcagcactt ccttgacagc taaaggaatc gatttgatgc aacgggcgta
   128221 ccataatcct tcaagattag caatagaacc atctgctgca atgtgtcccc atccgtctgt
   128281 catattgaat aatgaagcaa aatcctgtcc tacttctgct tccatttgcg aagttgccat
   128341 agaagattcc aatgcaacat tatttgggtt ccacagcatc gcatagttgt aagctaataa
   128401 agcaggcatc aatgtttcag cattcatttg tccccagtaa cggcctgctg aatgccatgg
   128461 gatcgatcct gcgcgtaatc gctgactgac ttcatccaag acctctatca tatggtcgcg
   128521 ggtggctaga taatctggag tgagcttatc tccttcgcta attgcaggca tatctgaagg
   128581 aatataattt tctctccatc caagatgttc atctaccatc ttgttcaaca acattttata
   128641 aactggtcca ttttcagctt tgtcgcctat aaagacggcc ttgatatcca tatctttcat
   128701 ttttcttccc tccatatttt gttggtcaat gtcttgcaga tacatgtgtt tatctgtaac
   128761 acctcttcac tatagcgcca aaaatgagaa attttttttt ataacatcaa atccacgtag
   128821 atttttacaa acaaaaataa ataaagtcgg atttttctga taattcaacg caaaaaagcg
   128881 aacaattttt caataaatca gtcttctaaa atagataacc taaaaaaagc gaacaaacaa
   128941 ataaaatgac tgtccttcat tcactaaaca tatttt
//
LOCUS       DACGDM010000002        87998 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.002, whole genome shotgun sequence.
ACCESSION   DACGDM010000002 DACGDM010000000
VERSION     DACGDM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.002"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..704
                     /locus_tag="IXR05_000110"
     CDS             <1..704
                     /locus_tag="IXR05_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAQ4258664.1"
                     /translation="SNYYEGGNEIVSKMKISEVTLDETDDFTYYKGYKKGWNTLCTYL
                     KIRVPFDDLDFFESHKDLITQTASSIYDKQGDNVLVDTILVPLPENYEVINFSQLKIS
                     DVVSQAIEDAESFMSNGEYQRAFDRVHTAFHGYLIEILKKYEITVPRDENLSKLYSRI
                     QQLIEKEIQPTELADIVKTTIRSSNGMISSLNEARNRHSLAHPNTNIIGKREAKLIIG
                     ISSTVTDYISGYLDK"
     gene            771..1265
                     /locus_tag="IXR05_000111"
     CDS             771..1265
                     /locus_tag="IXR05_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4258665.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            1321..1959
                     /locus_tag="IXR05_000112"
     CDS             1321..1959
                     /locus_tag="IXR05_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258666.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            2031..2426
                     /locus_tag="IXR05_000113"
     CDS             2031..2426
                     /locus_tag="IXR05_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4258667.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            2410..4863
                     /locus_tag="IXR05_000114"
     CDS             2410..4863
                     /locus_tag="IXR05_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4258668.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            4860..6887
                     /locus_tag="IXR05_000115"
     CDS             4860..6887
                     /locus_tag="IXR05_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258669.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            6884..7906
                     /locus_tag="IXR05_000116"
     CDS             6884..7906
                     /locus_tag="IXR05_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4258670.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            7923..8852
                     /locus_tag="IXR05_000117"
     CDS             7923..8852
                     /locus_tag="IXR05_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4258671.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            9097..9213
                     /locus_tag="IXR05_000118"
     CDS             9097..9213
                     /locus_tag="IXR05_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAQ4258672.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            9229..10032
                     /locus_tag="IXR05_000119"
     CDS             9229..10032
                     /locus_tag="IXR05_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4258673.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            10207..10503
                     /locus_tag="IXR05_000120"
     CDS             10207..10503
                     /locus_tag="IXR05_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258674.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            10510..12462
                     /locus_tag="IXR05_000121"
     CDS             10510..12462
                     /locus_tag="IXR05_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAQ4258675.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(12534..13031)
                     /gene="dfrG"
                     /locus_tag="IXR05_000122"
     CDS             complement(12534..13031)
                     /gene="dfrG"
                     /locus_tag="IXR05_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAQ4258676.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            13393..14433
                     /locus_tag="IXR05_000123"
     CDS             13393..14433
                     /locus_tag="IXR05_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4258677.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            14531..14719
                     /locus_tag="IXR05_000124"
     CDS             14531..14719
                     /locus_tag="IXR05_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4258678.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(14777..15130)
                     /locus_tag="IXR05_000125"
     CDS             complement(14777..15130)
                     /locus_tag="IXR05_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4258679.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            15661..16083
                     /locus_tag="IXR05_000126"
     CDS             15661..16083
                     /locus_tag="IXR05_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4258680.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            16080..16310
                     /locus_tag="IXR05_000127"
     CDS             16080..16310
                     /locus_tag="IXR05_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4258681.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            16808..17008
                     /locus_tag="IXR05_000128"
     CDS             16808..17008
                     /locus_tag="IXR05_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4258682.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            17035..18228
                     /locus_tag="IXR05_000129"
     CDS             17035..18228
                     /locus_tag="IXR05_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4258683.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(18296..19861)
                     /gene="guaA"
                     /locus_tag="IXR05_000130"
     CDS             complement(18296..19861)
                     /gene="guaA"
                     /locus_tag="IXR05_000130"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAQ4258684.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(19920..20843)
                     /locus_tag="IXR05_000131"
     CDS             complement(19920..20843)
                     /locus_tag="IXR05_000131"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAQ4258685.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            21039..21644
                     /locus_tag="IXR05_000132"
     CDS             21039..21644
                     /locus_tag="IXR05_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4258686.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            21952..22968
                     /locus_tag="IXR05_000133"
     CDS             21952..22968
                     /locus_tag="IXR05_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4258687.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            23109..24410
                     /locus_tag="IXR05_000134"
     CDS             23109..24410
                     /locus_tag="IXR05_000134"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAQ4258688.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            24456..25118
                     /gene="deoC"
                     /locus_tag="IXR05_000135"
     CDS             24456..25118
                     /gene="deoC"
                     /locus_tag="IXR05_000135"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAQ4258689.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            25139..25537
                     /locus_tag="IXR05_000136"
     CDS             25139..25537
                     /locus_tag="IXR05_000136"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAQ4258690.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            25603..26685
                     /locus_tag="IXR05_000137"
     CDS             25603..26685
                     /locus_tag="IXR05_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4258691.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            26897..28459
                     /locus_tag="IXR05_000138"
     CDS             26897..28459
                     /locus_tag="IXR05_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258692.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            28452..29585
                     /locus_tag="IXR05_000139"
     CDS             28452..29585
                     /locus_tag="IXR05_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258693.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            29585..30541
                     /locus_tag="IXR05_000140"
     CDS             29585..30541
                     /locus_tag="IXR05_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258694.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            30640..31806
                     /gene="deoB"
                     /locus_tag="IXR05_000141"
     CDS             30640..31806
                     /gene="deoB"
                     /locus_tag="IXR05_000141"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAQ4258695.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            31830..32648
                     /locus_tag="IXR05_000142"
     CDS             31830..32648
                     /locus_tag="IXR05_000142"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4258696.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            32665..33372
                     /gene="deoD"
                     /locus_tag="IXR05_000143"
     CDS             32665..33372
                     /gene="deoD"
                     /locus_tag="IXR05_000143"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4258697.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(33670..34356)
                     /gene="gpmA"
                     /locus_tag="IXR05_000144"
     CDS             complement(33670..34356)
                     /gene="gpmA"
                     /locus_tag="IXR05_000144"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4258698.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(34528..35109)
                     /locus_tag="IXR05_000145"
     CDS             complement(34528..35109)
                     /locus_tag="IXR05_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4258699.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(35242..35925)
                     /gene="rpiA"
                     /locus_tag="IXR05_000146"
     CDS             complement(35242..35925)
                     /gene="rpiA"
                     /locus_tag="IXR05_000146"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAQ4258700.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            36244..36657
                     /gene="rpsL"
                     /locus_tag="IXR05_000147"
     CDS             36244..36657
                     /gene="rpsL"
                     /locus_tag="IXR05_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAQ4258701.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            36741..37211
                     /gene="rpsG"
                     /locus_tag="IXR05_000148"
     CDS             36741..37211
                     /gene="rpsG"
                     /locus_tag="IXR05_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAQ4258702.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            37305..39392
                     /gene="fusA"
                     /locus_tag="IXR05_000149"
     CDS             37305..39392
                     /gene="fusA"
                     /locus_tag="IXR05_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4258703.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            39564..40751
                     /gene="tuf"
                     /locus_tag="IXR05_000150"
     CDS             39564..40751
                     /gene="tuf"
                     /locus_tag="IXR05_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4258704.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            41158..41466
                     /gene="rpsJ"
                     /locus_tag="IXR05_000151"
     CDS             41158..41466
                     /gene="rpsJ"
                     /locus_tag="IXR05_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAQ4258705.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            41497..42126
                     /gene="rplC"
                     /locus_tag="IXR05_000152"
     CDS             41497..42126
                     /gene="rplC"
                     /locus_tag="IXR05_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAQ4258706.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            42154..42777
                     /gene="rplD"
                     /locus_tag="IXR05_000153"
     CDS             42154..42777
                     /gene="rplD"
                     /locus_tag="IXR05_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAQ4258707.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            42777..43067
                     /gene="rplW"
                     /locus_tag="IXR05_000154"
     CDS             42777..43067
                     /gene="rplW"
                     /locus_tag="IXR05_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAQ4258708.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            43106..43939
                     /gene="rplB"
                     /locus_tag="IXR05_000155"
     CDS             43106..43939
                     /gene="rplB"
                     /locus_tag="IXR05_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAQ4258709.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            43982..44260
                     /gene="rpsS"
                     /locus_tag="IXR05_000156"
     CDS             43982..44260
                     /gene="rpsS"
                     /locus_tag="IXR05_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAQ4258710.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            44283..44630
                     /gene="rplV"
                     /locus_tag="IXR05_000157"
     CDS             44283..44630
                     /gene="rplV"
                     /locus_tag="IXR05_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAQ4258711.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            44644..45300
                     /gene="rpsC"
                     /locus_tag="IXR05_000158"
     CDS             44644..45300
                     /gene="rpsC"
                     /locus_tag="IXR05_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAQ4258712.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            45303..45737
                     /gene="rplP"
                     /locus_tag="IXR05_000159"
     CDS             45303..45737
                     /gene="rplP"
                     /locus_tag="IXR05_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAQ4258713.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            45727..45915
                     /gene="rpmC"
                     /locus_tag="IXR05_000160"
     CDS             45727..45915
                     /gene="rpmC"
                     /locus_tag="IXR05_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAQ4258714.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            45940..46206
                     /gene="rpsQ"
                     /locus_tag="IXR05_000161"
     CDS             45940..46206
                     /gene="rpsQ"
                     /locus_tag="IXR05_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAQ4258715.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            46264..46632
                     /gene="rplN"
                     /locus_tag="IXR05_000162"
     CDS             46264..46632
                     /gene="rplN"
                     /locus_tag="IXR05_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAQ4258716.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            46669..46977
                     /gene="rplX"
                     /locus_tag="IXR05_000163"
     CDS             46669..46977
                     /gene="rplX"
                     /locus_tag="IXR05_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAQ4258717.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            47005..47544
                     /gene="rplE"
                     /locus_tag="IXR05_000164"
     CDS             47005..47544
                     /gene="rplE"
                     /locus_tag="IXR05_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAQ4258718.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            47563..47748
                     /locus_tag="IXR05_000165"
     CDS             47563..47748
                     /locus_tag="IXR05_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAQ4258719.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            47784..48182
                     /gene="rpsH"
                     /locus_tag="IXR05_000166"
     CDS             47784..48182
                     /gene="rpsH"
                     /locus_tag="IXR05_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAQ4258720.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            48214..48750
                     /gene="rplF"
                     /locus_tag="IXR05_000167"
     CDS             48214..48750
                     /gene="rplF"
                     /locus_tag="IXR05_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAQ4258721.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            48911..49267
                     /gene="rplR"
                     /locus_tag="IXR05_000168"
     CDS             48911..49267
                     /gene="rplR"
                     /locus_tag="IXR05_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAQ4258722.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            49288..49788
                     /gene="rpsE"
                     /locus_tag="IXR05_000169"
     CDS             49288..49788
                     /gene="rpsE"
                     /locus_tag="IXR05_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAQ4258723.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            49803..49982
                     /gene="rpmD"
                     /locus_tag="IXR05_000170"
     CDS             49803..49982
                     /gene="rpmD"
                     /locus_tag="IXR05_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAQ4258724.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            50026..50466
                     /gene="rplO"
                     /locus_tag="IXR05_000171"
     CDS             50026..50466
                     /gene="rplO"
                     /locus_tag="IXR05_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAQ4258725.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            50466..51761
                     /gene="secY"
                     /locus_tag="IXR05_000172"
     CDS             50466..51761
                     /gene="secY"
                     /locus_tag="IXR05_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAQ4258726.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            51823..52470
                     /locus_tag="IXR05_000173"
     CDS             51823..52470
                     /locus_tag="IXR05_000173"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAQ4258727.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            52661..52879
                     /gene="infA"
                     /locus_tag="IXR05_000174"
     CDS             52661..52879
                     /gene="infA"
                     /locus_tag="IXR05_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAQ4258728.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            52912..53028
                     /gene="rpmJ"
                     /locus_tag="IXR05_000175"
     CDS             52912..53028
                     /gene="rpmJ"
                     /locus_tag="IXR05_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAQ4258729.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            53046..53411
                     /gene="rpsM"
                     /locus_tag="IXR05_000176"
     CDS             53046..53411
                     /gene="rpsM"
                     /locus_tag="IXR05_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAQ4258730.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            53439..53828
                     /gene="rpsK"
                     /locus_tag="IXR05_000177"
     CDS             53439..53828
                     /gene="rpsK"
                     /locus_tag="IXR05_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAQ4258731.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            53908..54846
                     /locus_tag="IXR05_000178"
     CDS             53908..54846
                     /locus_tag="IXR05_000178"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAQ4258732.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            54874..55254
                     /gene="rplQ"
                     /locus_tag="IXR05_000179"
     CDS             54874..55254
                     /gene="rplQ"
                     /locus_tag="IXR05_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAQ4258733.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            55526..56365
                     /locus_tag="IXR05_000180"
     CDS             55526..56365
                     /locus_tag="IXR05_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4258734.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            56341..57210
                     /locus_tag="IXR05_000181"
     CDS             56341..57210
                     /locus_tag="IXR05_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4258735.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            57200..57997
                     /locus_tag="IXR05_000182"
     CDS             57200..57997
                     /locus_tag="IXR05_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAQ4258736.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            58200..58946
                     /gene="truA"
                     /locus_tag="IXR05_000183"
     CDS             58200..58946
                     /gene="truA"
                     /locus_tag="IXR05_000183"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4258737.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(59279..61948)
                     /locus_tag="IXR05_000184"
     CDS             complement(59279..61948)
                     /locus_tag="IXR05_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4258738.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(62186..62374)
                     /locus_tag="IXR05_000185"
     CDS             complement(62186..62374)
                     /locus_tag="IXR05_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAQ4258739.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            62644..63006
                     /locus_tag="IXR05_000186"
     CDS             62644..63006
                     /locus_tag="IXR05_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4258740.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            63058..64740
                     /locus_tag="IXR05_000187"
     CDS             63058..64740
                     /locus_tag="IXR05_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAQ4258741.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            64857..66893
                     /gene="recG"
                     /locus_tag="IXR05_000188"
     CDS             64857..66893
                     /gene="recG"
                     /locus_tag="IXR05_000188"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAQ4258742.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            66942..67943
                     /gene="plsX"
                     /locus_tag="IXR05_000189"
     CDS             66942..67943
                     /gene="plsX"
                     /locus_tag="IXR05_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAQ4258743.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            68065..68307
                     /gene="acpP"
                     /locus_tag="IXR05_000190"
     CDS             68065..68307
                     /gene="acpP"
                     /locus_tag="IXR05_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4258744.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            68575..69579
                     /locus_tag="IXR05_000191"
     CDS             68575..69579
                     /locus_tag="IXR05_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258745.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            69580..70524
                     /locus_tag="IXR05_000192"
     CDS             69580..70524
                     /locus_tag="IXR05_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258746.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            70524..71486
                     /locus_tag="IXR05_000193"
     CDS             70524..71486
                     /locus_tag="IXR05_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258747.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            71513..72427
                     /locus_tag="IXR05_000194"
     CDS             71513..72427
                     /locus_tag="IXR05_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258748.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            72453..74234
                     /locus_tag="IXR05_000195"
     CDS             72453..74234
                     /locus_tag="IXR05_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4258749.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            74582..75268
                     /locus_tag="IXR05_000196"
     CDS             74582..75268
                     /locus_tag="IXR05_000196"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4258750.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            75288..78869
                     /gene="smc"
                     /locus_tag="IXR05_000197"
     CDS             75288..78869
                     /gene="smc"
                     /locus_tag="IXR05_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAQ4258751.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            78878..79687
                     /locus_tag="IXR05_000198"
     CDS             78878..79687
                     /locus_tag="IXR05_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4258752.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            79698..80696
                     /gene="ftsY"
                     /locus_tag="IXR05_000199"
     CDS             79698..80696
                     /gene="ftsY"
                     /locus_tag="IXR05_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAQ4258753.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            80883..83150
                     /gene="gshAB"
                     /locus_tag="IXR05_000200"
     CDS             80883..83150
                     /gene="gshAB"
                     /locus_tag="IXR05_000200"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAQ4258754.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(83239..83691)
                     /locus_tag="IXR05_000201"
     CDS             complement(83239..83691)
                     /locus_tag="IXR05_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAQ4258755.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            83841..84791
                     /locus_tag="IXR05_000202"
     CDS             83841..84791
                     /locus_tag="IXR05_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4258756.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            84784..85743
                     /locus_tag="IXR05_000203"
     CDS             84784..85743
                     /locus_tag="IXR05_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4258757.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            85740..86495
                     /locus_tag="IXR05_000204"
     CDS             85740..86495
                     /locus_tag="IXR05_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4258758.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            86518..87471
                     /locus_tag="IXR05_000205"
     CDS             86518..87471
                     /locus_tag="IXR05_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4258759.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
BASE COUNT        28930 a        15699 c        18627 g        24742 t
ORIGIN      
        1 cttcaaatta ttatgaagga ggtaacgaga ttgtttctaa aatgaaaata tcagaggtaa
       61 ctttagatga gactgacgat tttacttatt ataaaggata taaaaagggc tggaatacgc
      121 tttgcacata tcttaaaata agagttcctt ttgatgattt agactttttt gaaagtcata
      181 aagatttgat tacccagaca gcaagctcca tatatgataa acaaggtgat aatgtattag
      241 tggatactat tttagtacca cttccagaga attacgaagt aattaacttt agtcagttga
      301 aaattagtga tgtggtttca caagctattg aagacgctga gtcttttatg agtaatggtg
      361 aatatcaacg tgcctttgac agagttcaca ctgcttttca tggatattta attgaaatac
      421 taaaaaaata tgaaattaca gttcctagag acgaaaatct atctaaatta tatagtagga
      481 tacaacaatt aattgaaaaa gaaattcaac ctactgaact tgctgatata gtgaagacaa
      541 cgataaggtc atcaaatgga atgattagct ctcttaatga agcaagaaat aggcattcac
      601 ttgcacaccc taatacaaat attattggaa agagagaagc aaaactaata ataggtattt
      661 caagtacagt tacagattat attagcggat accttgataa gtagcgtcat taactgattg
      721 ctactttttt tatgactatt tttataaaaa ggatgtgata agaattggaa atgaaagtct
      781 atgtggcaaa tttaggacgg tataatgaag gtgaattagt cggagcatgg tttactccac
      841 caattgatga ggaagaaatg gcagaaagaa tcggtttaaa tgaggactac gaagaatatg
      901 caatacatga ttttgagctt ccttttgatg tggacgaata cacgccgatt agtgaaatca
      961 accgtctatg tgaagccatt caagaaatcg aaggtacacc tatttataat gaactcaaag
     1021 aaattcaagg catgtggttt agtagcttgg aagaattact ggaaaacaaa gaggatattc
     1081 attgttatag tgattgtgat tcgatggaag atgtcgcccg ttattacgtg gaagaaacag
     1141 gacagcttgg tgaagtccct tccaatttac aaaattatat tgactaccaa tctttgggac
     1201 gtgatatgga aatagagggt aattacctag ttacctctca tggggtattt gaatattgtc
     1261 agtaagttta acaatccgtg ttataattaa attaataaat agcacggaga ggtataaatt
     1321 atggtaaatg tatttgaaaa tcttaaacta ttaaaactag acatgaaaga taaaggctgg
     1381 gtgatagatt ccttttactt tcgttacaaa cagcaaaatt atattgtact tgttaagcta
     1441 tttgaaaaag aggaaaaagt tccagaatat gctctgttaa aactagaatt tttaaaggaa
     1501 aacgattttt cagatatgct agctgtctat gctaattcgg taaaattata tacagacacg
     1561 aaaacaataa gagaatattt tggtatcgaa tacagtagta acttgggaga tgttttattt
     1621 caatttagcc aaactcttgc tcgatttatt ccgacagaag ttagtgagaa gaaaaatgaa
     1681 gaccaaaaag aagccatgtg tttctcatta agtcaaagtg attcagaaga tcccagaaaa
     1741 aaatattgtt tttcagttag aagaaatcct ttaaagggaa atggtgagct gggaaaacga
     1801 agtcctttta atgacaataa aacgagattg tatagaccca gcttatatga acgattaggg
     1861 tcagatacca atttaagttt cagatattca atgaatccag atgatgaaga aactgatgaa
     1921 ggtattattg caaaatggac aaaaaataaa attgaatagt taaagcattg aaagagcaat
     1981 cacctatttt gattgttctt tttctatttt tacggaaagg acgtgaagac atgaaaaaaa
     2041 taagaagtta caccagtatt tggtcagtag aaaaagtgat ttatgcgatt aatgatttac
     2101 aactcccttt cccaattacc tttacgcaaa tgacatggtt tatcgtttct ttgtttgtcg
     2161 tcatactctt tggcagttta ccaccacttt ctctgattga cggagcacta ctcaaatact
     2221 tagggattcc cattgttctc actgggttca tgtgccaaaa gacctttgac ggaaagaaac
     2281 cctatggatt tctaaagtct atcattacct atgctctacg ccctaaagta acctacgctg
     2341 gcaaacaaat acgattaaaa aaagaaacaa tgaatgaatc gattacgatt gtaaggagtg
     2401 aacaactaga tggcatatcc gattaaatat atggaagata atctcgtatt taatcatgat
     2461 ggcgaagtat tcgcttatta tgaattaatt ccctataatt acagtttttt aagttccgat
     2521 gaaaaaattc aagttcatga taatttctgt caattgattg cccaaaatcg tgatggcaag
     2581 attcatgctc tgcaactagc aaccgaatca agtattcgag ccacacagga acaatcgaaa
     2641 aaagaaatca ctggacgatt aaaagagata gcttacgaaa aaatagatga acagaccgaa
     2701 gcgttaattt ctatgattgg tgacaatcaa gtagactatc gcttttttat tggttttaaa
     2761 ctctacctca atgaacagga agtatccgta aaaaatgttg ggaaagaaat tcaaaaagca
     2821 tttgcggaat tctttcatgg tgtgaatcac aaattaatgg gcgattttgt ttctatgcct
     2881 atggcggaaa tcgaacgctt ttctaagatg gaacagttgt tagaaagtaa attatccaga
     2941 cgctttcaga ttcgtaaatt ggagaaagat gattttggtt atattattga acatctttac
     3001 gggcaaacag gtgtcccttt tgatgactac gactaccatt taccgaaacg atacgaagat
     3061 aaaaaagtgt tggtaaagaa atacgatatt ctcaaaccca ctcgctgttt aatcgaagaa
     3121 aatcaacgct atttacggat tgaacaggaa gataccacta cttatgtggc gtattttaca
     3181 attaatagta ttgttggtga attggatttc cctaatagtg aaatttttta ttaccagcaa
     3241 cagcagttta ctttccccgt tgataccagt atgaatgttg aaattgtcgc caataaaaaa
     3301 gccttatcta ccgttcgcaa taaaaagaaa gaactgaaag atttagatag ccacgcatgg
     3361 gaaagcgaca acgaaaccag tactaatgtg gtggacgctt tagaatctgt cgatgaatta
     3421 gaaagtaatt tagaccaaac caaagaatct atgtacaaac taagctatgt ggtacgggta
     3481 tcagcaaaga atttggacga gctgaaacaa cgttgtgatg aagtaaaaga tttttatgat
     3541 gatctgtcta tcaaattagt acgacctttt ggcgatatgc taggcttgca taatgaattt
     3601 attccctcaa gcaagcgata tatcaatgac tatattcaat atgtcacgtc ggattttttg
     3661 gctggtcttg gtttcggtgc tacacaaatg attggtgaaa attctggtat ttacgtcggt
     3721 tacaatctcg atacaggcag aaatatttat ctccaaccta gccttgcaag tcaaggaatt
     3781 aaaggctctg taacaaatgc attagcgtcc gcttttattg gttcattagg tggcggaaaa
     3841 tcattctcta acaatatgct ggtctattat tcagtactct ttggcggaca ggcaaccatt
     3901 gttgacccaa aagctgaacg tggtgaatgg aaagaaacct tacctgatat tgcccatgaa
     3961 atcaatattg ttaatctcac gagtgagaac gacaataaag ggttacttga cccttatgtg
     4021 attttaaaac tcccgaaaga ttcagaaagc cttgccattg atattctcac gttcttaaca
     4081 ggtatttcca gccgagatag cgagaagttt cctgtcctgc gtaaagctat tcggagtgta
     4141 actcaaagca aacaacgagg gttgttattg gtgattgatg aattgcgaaa agaagatacg
     4201 cccatcagca atagtattgc tgaccatatc gaaagctttg tcgattatga ttttgcccat
     4261 ctgttattca gtgatggcag tgtcacccaa tccattagct tggaaaaaca actcaatatt
     4321 attcaagtgg cagatttggt cttacccgat tccaatagct cttttgaaga atacactacc
     4381 atggaattat taagtgtggc aatgctgatt gtcattagta cctttgcttt agactttatc
     4441 cactctgacc gttccatttt taaaattgtt gaccttgatg aggcttggag ttttttacaa
     4501 gtggcacaag gaaaagctct atctatgcga ttggttcgag caggacgtgc catgaatgca
     4561 ggggtctatt tcgttactca aaacgcggac gatttactag atgaaaagat gaagaataat
     4621 attggcttga aatttgcctt tcgttccact gacctagtgg aaatcaaaaa gaccttagaa
     4681 ttttttggtg tggacaagga agatgaaaac aatcagaaac gcttacgtga attagaaaat
     4741 ggacaatgtt tagtttcaga catctatggt cgtgtagggg ttatgcagtt tcacccgatt
     4801 tttgaagagt tgcttcatgc ctttgatacc agaccgcctg tgcgaaatga ggtggaagaa
     4861 tgacacaaaa acaaaagaaa tttcttcact atagttggat aacgctcctt tgtgtgggcg
     4921 ttattttact tttattaggc acgctgggca atgcagtaca agcgacaggc ttagttgatg
     4981 aaaccattga tacaagcaat gaatactcca agtatggttt gaatcaatat cagcttgatt
     5041 attatgtgga caatagctgg ggctggcttc catggaattg gagtgatggc ataggacaat
     5101 cggtgatgta tggattgtat gccattacta attttatttg gacaatttct ctttatctat
     5161 cgaacgccac aggttatttg gtgaaagaag cctatgcctt agatttcatt agtcaaacat
     5221 cccaagcaat tggcgaaaac atgcagacga ttgcaggcat tacaccgaat ggcttttcca
     5281 gttcagggtt ttatgtcggt ttcctccttc tttttattct cattgttgga atctatgttg
     5341 cctatacagg attggttaag cgagaaacga cgaaagtgat acgagctgtt ttaaactttg
     5401 tcgtggtgtt tattctatcg gcttccttta ttgcgtatgc acccgattat attgcgaaaa
     5461 tcaatgattt ttccaaagat gtcagtaccg ccagtctgaa tattgggaca aaaattgttc
     5521 ttcctaacac ggatagtcaa gggaaagaca gtgtggacat gatacgtgac agcttattct
     5581 ctgttcaagt aaagcaacca tggctattgc ttcaatatgg ctccactgat gtagaagcgt
     5641 taggggaaga acgtgtggaa agtttattgt ctaccagtcc agatacaaac aatggtgaag
     5701 atagagaaaa tgtagtgatt gaagaaattg aagatcatga caatacctat ttaaccctac
     5761 cgaagacgat ttccagatta ggaacagtct tctttttgtt tgtattcaat attggtatct
     5821 cgatttttgt tttccttcta acaggaatca tgattttttc gcaagtgcta tttattattt
     5881 tcgctatgtt tttgccaatc agtttcctat taagtatgtt gccgagtttt gatggcatgg
     5941 gcaggcatgc cattaccaag ttatttaatg tgattatgac aagggctggt attaccttga
     6001 ttattaccgt tgcctttagt atttccacta tgctttattc gctgtcagca agttctccct
     6061 ttttcatgat tatgttttta caaattgtga cctttgcagg gatttatttt aaactgggcg
     6121 atttaatgag cctattcact ttacaaagca acgactctca aaacatgggc agacaagtgt
     6181 ttcgcagacc tcgtcaaatg atgaatcgac aaaccagaag atttcaacgc agtatgagta
     6241 agatttttcg tggaaaagca gggtcaacga agcaaaagac aatgacaaca aagcagaatc
     6301 aaaccaataa agctaaccat actcgtcaaa atgaacggac tacaccaaag aaagaaacag
     6361 cactttccaa tgtgaaaaag caacaaggcg gtatcgggca acgattaggt gaaaagacag
     6421 cccatgtatt ggacacgaaa aatcgtctag tcaataaaag aaagcaggca aaacaacaga
     6481 tacaggcgac accaacccat gtcaaatatg cccttcatca aggaaaagag aatgtcactc
     6541 ataatgtaac agactttaaa caatctatgg cagataccaa agctcaacgc aaacaacagc
     6601 gtatgaacca gcaggagcaa aaacgaaaga acattgctca aaagcgtttg gagctggata
     6661 aagcaaaaga aaaaagacga aaagaaaacc catcatctcc tgttcagaat aaccagcagc
     6721 atgttcgcaa gcgtcagcaa accgtcacgc ctgttttgtc acaaaacact aaacgtgaaa
     6781 atcatcagcg accattgaaa aaagagcaaa aacaaaagac accaccgaag caattcaatc
     6841 agaggaagct aaataaaaga acggataagc gaggacaaca aacatgaagc taaaaataac
     6901 agtgatttgt agtgtggtct tctctctctt cttttttctc ttattattcc tagtcatttt
     6961 ctttgcagat gatacggaca gtggcgaaaa caacaaggat tcttctattc cacaaggcgg
     7021 tgtgaccgtt tcaccagaag tgttggcaca ccgtccgttg attgaaaaat atggtaagga
     7081 atatgggatt gaagactatg tttcttatat cttagccatt atgcaagtgg aatcgggcgg
     7141 tacagcagaa gatgttatgc aaagttccga atctttgggt ttaccgccca acagtttgag
     7201 taccgaagag tccatcaaac aaggggttaa atatttcagt gaattattaa ccagtgcaga
     7261 acaacaagga gtggatatag attctgttat ccaatcttat aattatggcg gtggcttttt
     7321 aaattatgtg aggagtcatg ggaaaaaata tacctatgaa ttagccgaac agttttctaa
     7381 agagaagtcg ggtggtcaaa aagcagacta tcccaatcct atagccatac ctgtgaatgg
     7441 tggttggcga tataactatg gaaatcagtt ttatgttcag ttggtttcac aatacctaac
     7501 cgacacttcc ccaacagaat ttgatgatga aaccgtgcaa gtcattatgg acgaagcctt
     7561 gaaatacgaa gggtttccct atgtctttgg aggggcgtcg cctaccacct cttttgattg
     7621 tagtggctta atacaatggg tgtatgacaa agctggcatt tctctccctc gtgtcgccca
     7681 agatcagtat gacgctacgc aagaaatctc tatggaagaa gcccaagcag gcgaccttat
     7741 cttctttcat tcaacctata atgcaggcac atatgtgact catgtggcga tatatttaga
     7801 gggaaatcgc ttttatcatg caggcgaccc aatcggttat ggcgacttaa gcagtcgtta
     7861 ttggcaagac catctgattg gggctagacg tgttattcat aactaagaaa ggaatgaatc
     7921 aaatgattat aaaaatcgag cgaaaagaaa agaaggagaa accaaagaaa tctaaaaaac
     7981 cgagcaagca aagaaaagtt ccgatgatta aagttggcac gcataagaaa ttaacctttg
     8041 ttttatgggt tttattgatt ggtagtgtcg gatttggaat ctataaaaat tttactgcca
     8101 ttgacactca tactgtccgt gaaacagaaa tcattaaaca gcagattgtc gataccaacc
     8161 aagtagaaag ttttgtgaaa tcctttgcga aagactactt ttcgtggcaa caatcccaag
     8221 aagccattga taaacgaaat gaaaaattga cccattattt gacggaagaa ttgcaggtat
     8281 taaatgaaga aatgattcgt aaggatattc ctactagttc tagtgtgaac gatatacagg
     8341 tgtggcaggt ttctcaagtg aatgagaaca cctttgaggt actgttttct gttgaacaag
     8401 ttattaccga agacaaagac aaggaaacta tatcgtctag ctttcatgtg gttgtccata
     8461 tagatgaatc agataatatg gttattatca aaaatccgac aatgagtaag aaacctcaaa
     8521 aatcggacta ccaacccaaa cagctagaaa gtgaccatac agtagataca gaaacgatgg
     8581 acgaaatcac tagcttttta gaaacgttct tccagctcta tcctaccgcc acagaaaaag
     8641 aattgactta ctatgtaagt aatcatgtgt tacctatgat taacaaggaa tatgttttcg
     8701 aggaattggt gaatcctatc tttaccagaa aagataacca agtaatcgtg aatgtcgctg
     8761 tgaaatattt agatcaagaa acaaaggcaa cccaaatctc gcaatttgag ttgatattag
     8821 aaaaacaaga taattggaag attgtaaaat aacaaatatt ggtacatgat tacagatact
     8881 ttgtaatcat gtactctttt tgataaaaaa ttggagattc ctttacaaat atgctcttac
     8941 gtgctattat ttaagtgact atttaaaagg agttaataaa tatgcggcaa ggtattctta
     9001 aataaactgt caatttgata gcgggaacaa ataattagat gtcctttttt aggagggctt
     9061 agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta tccagagaat
     9121 atctgtatgc tttgtatacc tatggttatg cataaaaatc ccagtgataa aagtatttat
     9181 cactgggatt tttatgccct tttgggtttt tgaatggagg aaaatcacat gaaaattatt
     9241 aatattggag ttttagctca tgttgatgca ggaaaaacta ccttaacaga aagcttatta
     9301 tataacagtg gagcgattac agaattagga agcgtggaca aaggtacaac gaggacggat
     9361 aatacgcttt tagaacgtca gagaggaatt acaattcaga caggaataac ctcttttcag
     9421 tgggaaaata cgaaggtgaa catcatagac acgccaggac atatggattt cttagcagaa
     9481 gtatatcgtt cattatcagt tttagatggg gcaattctac tgatttctgc aaaagatggc
     9541 gtacaagcac aaactcgtat attatttcat gcacttagga aaatggggat tcccacaatc
     9601 ttttttatca ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt
     9661 aaagagaaac tttctgccga aattgtaatc aaacagaagg tagaactgta tcctaatatg
     9721 tgtgtgacga actttaccga atctgaacaa tgggatacgg taatagaggg aaacgatgac
     9781 cttttagaga aatatatgtc cggtaaatca ttagaagcat tggaactcga acaagaggaa
     9841 agcataagat ttcagaattg ttctctgttc cctctttatc atggaagtgc aaaaagtaat
     9901 atagggattg ataaccttat agaagttatt actaataaat tttattcatc aacacatcga
     9961 ggtccgtctg aactttgcgg aaatgttttc aaaattgaat atacaaaaaa aagacaacgt
    10021 cttgcatatt aagtagttca gttttggagt acaaaaagtg aaaatgtaaa cctaaatgag
    10081 tatcaaattg caactgaatt tgatactcgt tttttattgt taaatcaacg tttgttgtta
    10141 atttacacca caaaatgtaa gttaaaatgt atataaaaat gcgaacgtga aataattatt
    10201 gtaggaatgc aaattggtgt gttaaaatgg ttacaattta ctaagcaaaa aggggtgcat
    10261 tttcctatgc aatttcttga gccaaaaaat aagaacgcta agtctgtgga ttgggaaata
    10321 tcagagcaag taagggtgat agttaagcaa tacgctgaat atgcagagcg tactgaaagc
    10381 gaagcagtgg atgaattctt attgaacatt ttagacgata agaagtttat tgaatggatt
    10441 gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg gtatcaaaga tagagtgggt
    10501 tgatagacaa tgaccaagct taaaagatta gccacgaagg aagatgaaat tgtagatgtt
    10561 aaaattccga tttcaaacga agaattaaaa gatagggcta aacaatatga tttattaact
    10621 ccaaaacgat ttgcaacaag gtataacaaa atgttgttct tgccaacgtc ttttaaatgg
    10681 aacggttctg aatatcccat tcaatataat tactgcatca atccgttttg ttgtaatttt
    10741 gggaaagaac agcacaaatt caaagatgta aaagggaaac caagtcgata taaaatgact
    10801 ggtagttcca aagataaagg tcataaaggt atgtactgca atgacaatcc tattggcaga
    10861 ggtgtatcgc aaaactgtac agtaacccct ttatctaatt ggtctgttgt tgaagaaatt
    10921 aaacgcctta tagaaatcaa tagcatccaa gatgttgagc cagattatca atttcataaa
    10981 gaaggctgct cggaagaaga atcaacccca ttcaatgagc cgaagcaatt ttacaaaagg
    11041 gggaaaagta ggggcaaatc tcaacgctat caatgtaagg cgtgtaagaa gttcactaat
    11101 gttctaccaa aaagagaaga aaccactact tatcaccaac aaaagaacac cattcttcca
    11161 atgttcgcta agatggttgt tggaagggtt tcagtcagtc gtacttgtga tattttagga
    11221 attggagttg gaacctacta tcataagctg gagtggctgt ataggcgttg tttggagttt
    11281 ttagaacgat atgagacaca accccttcaa acaaagaaat ttaacgagat gtggcttaat
    11341 acggacaaga tgcactacta cctaaataac gtccgtaaga aaggacaagg ttcaaagaaa
    11401 tatacggggt ttgaagacct taatatgcaa acgtatatag ttgtatctgc tgaggtctta
    11461 tcaagatatg tgttccgttc tgatgttgcc tatgattgga atatttcaat ggatgaatta
    11521 aatgaagata caagaaaatt caaagaagac catctcaata cttttagtcg taaaaatgat
    11581 aggttagatt ggtcttatta tccacaagaa ccatccgcta acgatagcga aaataggaat
    11641 gcttatcttc acgaattagg gaaaattact aataggagta gatttgtcga tggtttaaat
    11701 gttgatgctc cttatactac aactgctcac tattggttaa ttaaacaaat ggttaatgcc
    11761 gacgaatggc gaatgattag tgatgatgac ttctctatta gaaacgcctt ttatagagta
    11821 ttcacgaaag aattaaggtt gagcgatgca catcatttta tttgccaagt taacaagacg
    11881 aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa aagcagaact gctcgattgg
    11941 ggagatatca gaggattcaa aacaaagttt ctacggactt tggcatctca ttatctaact
    12001 gaattactaa caagtcatca attccacgaa gaggctatta gtaaagatgg agaaagatat
    12061 cgcaaatatg ccgataaccc tatcaaacat ccattagcca ctaaggataa aggattttat
    12121 tcagttgatt gtagaacgga tttatctgct ctggaaccaa acgaaatcgc aaagatgcta
    12181 ttaaatgtta atgaccattc gaccaatagc tttattcaac agataagacg ttatatatca
    12241 tctcttgaaa gaccattaac aacagctcgt ggtgataaga agagctatat ttacgctaac
    12301 ttcaatccga agtatgctca atttgcgatt acaattctaa gaacttacta caacttttgt
    12361 cgccctttta aatcagcgga taaaaaggtt ttgacacctg ctcaaagatt agggattaca
    12421 gataaacaat ttgattggaa agatataatt tatttcaaat gacaaaaaga gcttggagta
    12481 atcccaagct cttgtgcttt atctttactg ttcttcttca attaacgcac ccgttaactc
    12541 aataagtttt ttctttcata tacatgaaaa tagtagttat acggattttt atcattcttt
    12601 atcccttttt gggcaaatac ctcattccat tcctcataat tcacttctgg aaaaaaagta
    12661 tctccttcga attcatgatg tatttttgtg atgtacattt tctcaacata agggaaaaac
    12721 aaattataaa tctgttctcc tccgaaaata aaaatttctt cttcgttttt acataactca
    12781 aaaacatctt ctattgaatg aacaatttca caaccattaa aggtaaaccc cttatctctc
    12841 gtcagaataa tatttcttct gtcaggtaag gctcttccga ttgattcaag gttcttccta
    12901 cctaatatta tcggatgtcc ctttgtagta tttttaacat attcccagtc cttgggaatc
    12961 ctccaaggaa tgtcattctc tttgccaatc actctattct tatccatcgc agcaatcaaa
    13021 gaaactttca tttataacac agccttttta actaatttac catctaattt cttatttcta
    13081 tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat aagcaatttt ttctataagt
    13141 tatattatca taataccaca aaatcacaaa ttttcattca attatcattt tcaattgcat
    13201 tttataaatc attttgtatg taatttggta tgtaagttaa aatgaaaaaa gtagtccatt
    13261 ttgaagtaca ttttgtcatt ttgtactcca aaactgaact acttacttgc atatatacgc
    13321 ctttatagtg gagtactaca tttacgagat tcggttagag tatcagaaaa agaaaaaata
    13381 aaagttacag aaatgtatac ttcaataaat ggtgaattat gtaagattga tagagcttat
    13441 tctggagaaa ttgttatttt gcaaaatgag tttttgaagt taaatagtgt tcttggagat
    13501 acaaaactat tgccacagag aaaaaagatt gaaaatccgc accctctact acaaacaact
    13561 gttgaaccga gtaaacctga acagagagaa atgttgcttg atgccctttt ggaaatctca
    13621 gatagtgatc cgcttctacg atattacgtg gattctacga cacatgaaat tatactttct
    13681 ttcttaggga aagtacaaat ggaagtgatt agtgcactgt tgcaagaaaa gtatcatgtg
    13741 gagatagaac taaaagagcc tacagtcatt tatatggaga gaccgttaaa aaatgcagaa
    13801 tataccattc acatcgaagt gccgccaaat cctttctggg cttccattgg tttatctgta
    13861 tcaccgcttc cgttgggaag tggaatgcag tatgagagct cggtttctct tggatactta
    13921 aatcaatcat ttcaaaatgc agttatggaa gggatacgct atggttgcga acaaggatta
    13981 tatggttgga atgtgacgga ttgtaaaatc tgttttaagt acggtttata ctatagccct
    14041 gttagtactc cagcagattt tcggatgctt actcctattg tactggagca agcctttaga
    14101 aaagctggaa cagaattgtt agagccatat cttagtttta aagtttatgc accacaggaa
    14161 tatctttcac gggcatataa cgatgctccc aaatattgtg caaatatcgt aaatactcaa
    14221 ctgaaaaata atgaggtcat tattattgga gaaattcctg ctcgatgtat tcaagattat
    14281 cgcaatgatt taactttttt tacaaatggg cttagtgttt gtttagcaga gctaaaagga
    14341 tatcaggtta ccactggcga acctgtttgc cagacccgtc gtctaaatag tcggatagat
    14401 aaagtaagat atatgttcaa taaaataact tagtgcgttt tatgttgtta tataaatatg
    14461 gtttcttatt aaataagatg aaatattctt taatatagat ttgaattaaa gtggaaagga
    14521 ggagattgtt attataaact acaagtggat attgtgtcct atttgtggaa ataaaacaag
    14581 actacgaata cgagtggata ctatacttaa aaatttccct ttatactgcc ccaaatgtaa
    14641 gaacgaaact ttaattaatg ttcaaaaaat gaatataata acaatcaaag agccagacgc
    14701 caagacgcag agccgataat ttgagaaatg aaactctcat cttatcggct ctttttgttt
    14761 atctgaattt tactgactag ccttcaatat ttcttgcttc attgatacct tttgctagtg
    14821 cttccattaa ggatagttct ttgtctgtaa agctatccat gtatttttct acctgtaacc
    14881 ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa ttcatcaata gatacatgga
    14941 gtaatgatac aagatcatac agcacttgtg tacttgggtg ttgtcctttg ttttctatat
    15001 ttgttaaata acgtgggtca atttcaatca ttgttcccac ttgttcacga gtgagacccc
    15061 gtttcattcg agcctcttta atcgctaaac caacggctct aaaatcgtat ttatcttctt
    15121 ttttacgcat actaaatcac ctctatacat tttactgttc ctatataacc ataaacaggt
    15181 atagaaaaac atgttatata gtttatgagt tcctatagaa cactgtggaa tttattaatg
    15241 cgatgaatcc aatttcaaat agaaaggtcg ctgattttat ttacctatac aactttataa
    15301 aatttagtca tactcctaga aagtagataa aattggcgac ttaatggagg gaaaagtcgc
    15361 catgagaaag ataatctgtc atctagttct cttaattaag ttcttatcaa aaaaacttat
    15421 ccacctgtac tggatagata tgaccatcaa tgtggttttg cagattacat agatagaaaa
    15481 atcaaagcat atgaacagag aaaacaatct gtttatgtgc ttttttggtc acttaataaa
    15541 tatcttttag gatttctctt catttatgca acaaatcccc cgttcgtgtc ggggtttagt
    15601 atgaagggag ataaagaagc acatgccact ccctttcacg acagaaaggg ggtgaaaagc
    15661 atgaaaccat cttcttttca agaaaccata gaaaatcagt ttgactatat ctgcaaacaa
    15721 gttattgaag atgaacgaaa agattacttc aaacatctag acagactatc agcaaaagaa
    15781 gtctcgtttt ctgatataga taactacctt gtcaactctt tttctactgt tgatacgtac
    15841 gtcactgatt tccaactatt taaattattt ggattaagaa tcaatgttga aagtgattta
    15901 ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga acattatttt acttcattac
    15961 tttatggata tgagtgatgt ggagattgcg gagttactaa atttgaatcg ttcgactgtt
    16021 tatcgtcatc gaataagtgg actagccatg attaaagaat tcatgaagga gtgtaaagaa
    16081 tgaaaacagc ttatccaagg gttcccttcc ccctcattgt aaaggcgaca gatggcgacg
    16141 tggaagcaat taatcagatt gttaaacatt atcgagggta tacctcaaaa cgttcattac
    16201 gtcgcatgac agacgaatat ggaaattctc atatggttat tgatgaaacc ctacgtggca
    16261 gaatggaaac gaaactcatc tctaagattt tatcgttcga aattaaatag tcccattttt
    16321 tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt gggaggtttg ttattccatc
    16381 aaagcatatt gtgtgttcag taggttttga taggctaaca agccaaacgt tctttgacaa
    16441 ccaaataaag gcaatcgaat acgtttcggt aagaaaagag ctgatgaact aacacgccat
    16501 gacctacaaa attagtgagc gattcatgtt agtaattcga aagtaatctt tagcaggatt
    16561 gctgccatga ctttcttatc gtgataatga tactcccgta tagccatagt ccgagcgtta
    16621 gaagcgtcac aggcaatggg tacggctaca tgagaaccat gcagaagtga aattcctgtg
    16681 agctttgcta gagctgttcg attgctaaga tattcttctc ttgtcagtgt attattataa
    16741 aactatttga tataattata ggtgaatatt ggagttttcc tagcctataa ttgggaaagg
    16801 agtaataatg ataacggtca caaaaaagga tttagttgag ctaggatatg gaacttcttt
    16861 ttcagcagac atcataaaaa aagcaaaaga attgatgatt acaaaagggc atatctacta
    16921 tcaatctcga aagctagata gagtccctcg tgaagctgtt gaagaaattc taggaattcg
    16981 gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt aaggagtaaa aactatggtt
    17041 aaagacccaa taaaaaaagc aaagaatgga acctattatt ttcgtgcaaa tctaggttat
    17101 gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat tcactactaa aaaagaagca
    17161 agagaagaat attcgaaact gctattgatg aaaccagaag aattaagtga gaataaggat
    17221 aaaatgacgt ttaaacatta tatctttgaa attttccttc catggtataa gacacaggta
    17281 aagctcagaa catatgaaaa tcgcttacca actattaaga agcatttctc ttattttgat
    17341 aaaatggctg tttccgatat tgagcctatt gatgtgcaaa attggcaact aaaattatca
    17401 aagaagtgta agtcttctta tgtaagagct gttcaaggac tattttcagt tgctatggat
    17461 cgagcaattg tccttgggat aaccaccaca aatccatcta agattattgg caatgtgaaa
    17521 aagcaaaagt ctaaaattga attttggaca aaagaagaat ttgaaaaagt aatctctcta
    17581 atttacaaag aagattacta tcaacacttt ttatttatct ctctgtggtt tttatttatg
    17641 actggaatgc gaattggtga agctactgcc attcaatggg aagatattga ttttgactca
    17701 ggagtactaa ccatcaacaa aacactctat tacaagaatc aatcgaatta tagatttgtt
    17761 gaaccaaaaa caaaggcgag cgttcgtcat attgtattag ataaatgcac attaacttat
    17821 ttatccgaat ggaaggaagt acaacaaaat ctaattcaga cagactttgt aatgagctat
    17881 aacggtattc ctacccaaaa acatacacta tcatatgcta ttgaacgcta tgctaagctg
    17941 gctggtatcc atcgaatcag aatccatggg ttacggcatt ctcatgcttc cttgttaatc
    18001 agtatgggag aaaatccact tatcattaaa gatcgtctag gacacgaaga tattgagacg
    18061 actttaggaa cgtatggaca tctttatcct aacagtaatt tcgaggtagc taacaaatta
    18121 aatggagcca tttcctttaa agaagcaaaa caaaattatg atacttcacc aaagaatcaa
    18181 tttactgtag actacttgcg aaacaaagaa atgaaaaaag tgcaataaaa gtgcagtaaa
    18241 aagataagaa gagccagaaa cccttggtat aagaggattt ctagctctcc tacaactatt
    18301 cccactccac tgttgctggt ggtttagaag tgatgtcata cacgatacgg ttgacgtggg
    18361 ctacttcgtt tacgatacgt acagagattt tttgcaagac ttcccatggg atacgggcaa
    18421 agtcagcggt cattccgtcg attgaagtta cagcacggat accgactgtg tagtcgtaag
    18481 tacgtccgtc acccataaca ccgacagagc ggatccctgg aagaacagtg aaatattgcc
    18541 agatatcacg gtcaagtcca gcagctgcga tttcttcacg caagatagca tcagattcgc
    18601 gtacgatttc tagcttgtct tcagtgattt cgccaagaac acgaatacca agaccaggac
    18661 cagggaatgg ctgacgccaa acgattgaat caggcatgcc taactgagtc cctaattcac
    18721 ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa ttcaaattgc atatcttctg
    18781 gcagtccacc tacattatgg tgagatttga tcgtctgtgc tgtttctgta ccagattcga
    18841 taacgtcagt atacaacgtt ccttgtgcta ggaaagagac gccttcttca ccagcaagtt
    18901 ttgttgcttc gtcatcaaaa acatatacga attcattccc aatgatttta cgtttttgtt
    18961 ctgggtcaga tacacctttc aacttgtcta agaagcgatc tcttgcatcg actttgatga
    19021 tgttcaagcc gaattttccg cctagacttt ccattacttg ttccgcttcg cctttgcgta
    19081 gcagaccgtg gtcaacaaag atagatgtca attggtcacc gatcgctttt tgtaaaagaa
    19141 ccccaacgac actagaatca acgccacctg aaagaccaag caagactttt ttgtcaccaa
    19201 cttgttcacg gattttttct acttgcatat cgataaagtt atccattgtc cagttacctt
    19261 cacagtgaca aacatcaaag gcaaagtggc gcagcaattc gattccgtat tcggaatgac
    19321 gtacttctgc atggaattgg ataccataaa aattacgtgt tgtgtcttgg atagaagcaa
    19381 tcggacaatc tttgcttgtt ccgactgttt caaagccttc aggaacttta gttaccaagt
    19441 caccatggct catccatact gtttgttgtt ttggtgtttc tttaaacaag acagcttgat
    19501 cgcttgttac ttctaacaag gctttcccat attcgcggtt tttagcaggc tctacggaac
    19561 cgccaagttt gtacgtgatc aattgcatac catagcaaat ccctaataca ggaataccta
    19621 aattgaagat ctcaggatcg atcccaaatg cattctcatc atatacactg tttggtccgc
    19681 cagaaagaat gattcccttt ggattcatcg cttttacttc ttctgcagta atgcggtggc
    19741 tcaataattc ggaaaagact ccaagatcac gaatacgtct tgtgatcaat tggttatact
    19801 gactaccgta gtctaatacg ataatctttt caacgttcgt catatcggca acgtttgtca
    19861 aatttattac ccctatccct ttaaatttta tctcaaaata gtcaaactat tttaaaatgc
    19921 taatattttc gcatgaaaat cgaatcgatg atatgatttt cagttttatg gagaattata
    19981 tcggctcttc ctcgtgtagg caagatatat tcctgtaaat ttttcaaatt cacatttttc
    20041 catacatctt ttgccatttt aaaggcttct tcacgatctc cgatagcaaa acgataataa
    20101 taattctctg gattttggaa agccgtatcc agtaacgcac caaaacgatc caaataccat
    20161 ttttcgatca gcacgggatc ggcatcgaca tagacagaaa aatcaaaaaa gtcgctgacg
    20221 tagatttgct gattcgcagg taattgaagc gtattgatcc cctcaacgat caagatatca
    20281 ggctgctgga tcaattcgta cttgtctgga atgatatcat acacatcatg tgagtaaaca
    20341 ggtactttta tctcttcctg accagatttt acacggttca agaaatcgat cagcatctcc
    20401 atatcataac tttcaggaaa tcctttacgg tccatgattc cacgctcttt taatatacga
    20461 tttggataaa gaaatccgtc agtcgtgatc agctgaacgt ttcttcgttt gaaggtacga
    20521 gacaaaatcg tctgcagcag tctggctgtt gtactttttc caacggctac acttccggcg
    20581 atcccgataa taaaaggcgg tacttctacg tatttatgaa gaaataaacc tttactcaag
    20641 aacaaagatt caaattcttt catataaaga taaatcagat gagcaagagg tacatagata
    20701 tctcgaacat cctgcatgga aatgcggtca ttcaaacttt tgatattatc tagttcatct
    20761 tgtgtcaaag gtgcttgccc attacgataa aattctcgcc attcttctct tgccacacgg
    20821 tagtagttca ttggatcatt catattagcc tcctgcgttc tcccatcaat ggaactattt
    20881 taacacaaaa taaacgcaaa ccccaccact taagagagat tgccgatctt tttgtataat
    20941 ctttataata gaaagaaacg gagtcttatt cttgacttgc gcacggatac ataaaaggat
    21001 agactgttgt catgaaagaa atgagaagga tggaagacat gacaaatcat tactattctg
    21061 aacgcccaga tacggcgcac gattttgaac aatgggcttt tgagttaaaa ggcagaacct
    21121 ttcaatttgt aacagattct ggtgtatttt cacgtgaaac agtggattat ggttcacgtg
    21181 tcctgattga tgctttcgat tgggaagagt tacctgatga aggaaagatc ttagatgtgg
    21241 gatgcgggta tggaccgatt gggttagctt tggcatttgc gacacagcgg tttgttgaaa
    21301 tggtcgacat taatgaacga gcggtaagtc tagcgcaagg aaacgcaaag cgtaaccaaa
    21361 tcgaacatgt tgatatccat caatcgaata tctatgaagc agttcatgaa gaaacctatg
    21421 cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa agttgtacat gaaattttga
    21481 caggcgcata tcctcggttg aagaagggcg gtacactgac aattgtgatc cagaagaaac
    21541 aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt tggtaatgca gaaatcgtca
    21601 caaaagataa aggatattat atcatcaaaa gtgtgaaaga ataactagct gaaaaatagt
    21661 ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt acgtatcagt tctttttttg
    21721 ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa aaagaaatag taggaacaga
    21781 gtcgttgttt tttacgataa aataaataag atacagaact tgtatagaag gctgccaagt
    21841 cggtagataa aggaggtttt tatcaaaaaa catactttcc ttttttctct attcttttct
    21901 tgggggtttt ggtacactga tagggaattt agatagaagg gagccaatag gatgaagctg
    21961 accatcagag atatcgcaga aatggcaggc gtatcagtaa caactgtctc acagattttg
    22021 aataacaaag gaagcagatt tagtgataag acaagaaaaa aagtgttgtc gatcgtgaat
    22081 gaacatcatt ataagcccga ttatttcgct tcaaatgtga tcaatcgaca ttcaaagacc
    22141 atcggaatga tcgtccctga tgtcactgat ttcttcttct ccaaactgat cgaaggtgta
    22201 gagagctatt tgaatccttt gggctatgtg atcatgttat gcaattctcg tcatagccaa
    22261 gaaaatgaga tcaagtattt acaagagctt tcccaccgct cagtggacgg aatcttgctg
    22321 gccacaccaa atattttacc tgagaaatat gcattagaca gcggttttta tcaaaaaatg
    22381 ccaatcattt taatcgatcg cggattgaat cgtcgggata acggacggct tatcgtaaag
    22441 gaatatgagg gcgcctatca agctgtttcg ctgtttattg aaaatggcca tacgaagatc
    22501 ggcatgctga aggaaaccac tggatactat caattagaag aacgtttcaa cggatatcgt
    22561 catgcgctga aagatcatgg cctgcctttt aatgggaaat ttgttgaaca tggagagttg
    22621 actgtccaag gtggatatac tgcatcaaaa aaattactca aacataaaga tatcacggct
    22681 attttttgcg ggaatgatgc catggcgatc ggatgctatc aggcgatcga tgaattgggc
    22741 aaaaaaatcc cagaagatat ctcagtcata ggattcgatg gattaaagct gtcagaatac
    22801 atgattccgc aattgacgac agtgcagcag ccaagttttg atattggatt ttatgctgca
    22861 cgtttcctga tcgatacgat cgaatttcct caaagaaaag ttccgaacaa agtgttcgaa
    22921 acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa agggctaact cggcggtata
    22981 ttgcttatgt aagcatttac aaaggctagt tagtgctttt tttattttta gtaaaccagt
    23041 ttactaaagt ggtttacctt tcctaaaaat aatgtataat accgaatgaa gacaaggagg
    23101 atcaggcaat gcgaatggtg gatctgattg aaaaaaagag ggatggaaac gagctgtcga
    23161 aagaggaaat cgagtacatc gtcacgaact atacgaatgg aaagattcca gattatcaag
    23221 tcagtgcatt attgatggca attttttatc aagacatgac aaatgaagaa atcacgaact
    23281 taacattggc gattgctaat tctggtgatg tcatcgattt gagttctctt gaaggaataa
    23341 aggtagataa gcattcgaca ggtggcgttg gtgacacgac cacattgatt ttagcccccc
    23401 tagtagctag tgtcggagtg acagtggcta aaatgtctgg acgcggtcta ggttacacag
    23461 gtggtacact agacaagcta gaagcaattc ccggatttca gatcgagctt tcggatgaag
    23521 aatttgtacg cattgttaat gaaagtaaag tagcggtaat tggtcaatca ggaaacttgg
    23581 caccggcgga caaaaaattg tatgccttgc gtgacgtcac agcgaccgtt gattctcttc
    23641 cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc aggagcagat gcaatcgttt
    23701 tggatgtgac cactggagac ggtgctttca tgaagaacat cgaagatgca agacgtctgg
    23761 caaagaccat gacgagcatt gggaaactgg ctaaccgaga aacagtggcg gttatctcag
    23821 atatgtcaga acctcttggc gaagctatcg gaaatagtct agaagttgtc gaggcaatcg
    23881 aaacattaca aggaaatggt ccagaagatc tagtagaaat gtgctacgcc ttaggaagcc
    23941 aaatggttgt tcttgctggc aaagctaaga caaccgatga agcaagaacg ttgcttcaag
    24001 aagctctgga atcaggtaaa gcgttagcaa aattcaaaga aatgatccaa aatcaagggg
    24061 gagacccagc gatcgtggaa catccagaac gaattttgac tgcacgctac acaatggagc
    24121 ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc aaatgaatta ggaattgctg
    24181 caatgatgct aggtgctggg cgtaaaacca aagaagaaga tattgatcac gctgttggat
    24241 tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg tgagtcacta ttgacgatct
    24301 atagtaacga cgaagaaatc acttctgtca ttgaattatt atataaaaat attgaaattg
    24361 gtgaatcggc aatgaagcca acgttgattc atgacatcat cacagaataa aggaaaaaag
    24421 cggactttac cgttttaaag aaaaggggaa aagaaatgga actaaaccga atgatcgacc
    24481 atactatttt gaaagcagac gcatctaaag aagctgtgat gcaaattatc gaagaagcaa
    24541 aaaaatacca tttttattct gtctgcatca atccagcatg ggttgcgcta gcgaaagaac
    24601 aattacaagg tgagccagta gccgtatgta cagtaatcgg gtttcctcta ggagcaaaca
    24661 cacccgagac aaaagcattt gaaacaacag atgccatcaa taacggtgca gatgaagtcg
    24721 atatggtcat caatatcggt gctttgaaat caaaggatga tcaacaagtc caaaaagata
    24781 tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt caaagttatt attgaaacat
    24841 cgttattaga tagagaagaa atcatccgag cttgcgaaat agcaaaagct gcaggcgctg
    24901 attttgtcaa aacatcaact ggtttctcaa caggcggagc aaaggtagag gatgtccgtt
    24961 tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc ttccggcggt atccataacg
    25021 aagaagaagc aatggcaatg atcgaagctg gtgctacaag aatcggaaca agcgcaggag
    25081 tagcaatcgt atctggttca actggtgaag gctattaatt ttttcaaagg agaagctcat
    25141 ggcagaactc aaacaagaat ggatcaacac agctattgaa gcgttagata aagcctatgt
    25201 tccttattcc cattttccgg taggcgcttg tctcgtaacg gaatcaggca agatttatca
    25261 aggcatcaac attgagaatg catcatttgg attaacgaat tgtgccgagc gcacagcttt
    25321 tttcaaagca gtatctgaag gagaaaaaac atttacgcat ctagtcgtag cggggcacac
    25381 ccccgatcct atctctcctt gtggtgcatg tcgacaagta atggcagaat tctgttcccc
    25441 tgatatgccg gttacgctag taggagacaa tggtgtgacg aaggcaacga ccgttcgtgc
    25501 actgctgcct tatgcattta ctgaaaaaga tctataactc atgttcattc agtcagctga
    25561 ctgttgaaaa ataaaacaat tattttagga ggctttacag aaatgaaaaa agcaaaatta
    25621 tttggtttag gtgctgtcgc actagcagca gggttatttt taggtgcatg cggcaacaac
    25681 ggctctactg attcatccgg tggcaaaagc tcatcagaca caacaactgc agcattgatc
    25741 acagacacag gtggtgtaga cgaccgttca ttcaaccagt cagcttggga aggactagaa
    25801 aaatggggga aagatcaagg actttcacga ggaaatgatg gcttccaata tttccaatct
    25861 tcaaatgaat cagattacat cccaaatatt gaccaagcat tgaatgctgg attcaaaacg
    25921 atttttggta ttggttataa actaaaacca gcgatccaag aacaagcaac aaacaataca
    25981 ggtacgaact ttgttattat cgatgatgtc atcgatggat tagataacgt tgtatctgca
    26041 actttcaaag acaacgaagc ttcttatctt gcaggtgttg cagcagctta tacgactgaa
    26101 acaaacgtag tcggctttat cggcggtgta aaaggtgaag taatcgatcg ttttgatgct
    26161 ggattcaaag ccggtgttga tgcaggtgcg aaagaattag gaaaagaaat caaagtattg
    26221 aatcaatatg ctggtgactt ctctgctcca gataaaggac gttcaattgc tcaaggtatg
    26281 tatgcacaaa acgcagatat catcttccat gcttcaggcg gtacaggtaa cggtgtattc
    26341 caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag tttgggttat cggtgttgac
    26401 cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg aaaagaaaaa cttcacattg
    26461 acatctacac tgaaagcagt tggaacagta gtagaagatt tggcacaaaa atcagcggac
    26521 ggtaaattcc ctggcggcga acacactgtt tatggattga aagaagacgg tgttggtcta
    26581 acagaaggac aactttctga cgaagcgaaa aaagcagttg atgaagcaaa agaaaaaatc
    26641 atttcaggtg acgtaaaagt tccagaaact cctgaagaaa actaaaacca tttctatagc
    26701 cttgttagac acatgtttga caaggctatg gtttgattag aacaagaatt gttcatttat
    26761 ccaagctgcc ttgtgacagt ttggataagg gaacaactcc ctgaagtaat gtttgtttca
    26821 aaagaagaac gctcactaag cgtgaatctt agtcaatcgt tgccctagat agaaatcgtt
    26881 aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata gaaatgcaga atattaccaa
    26941 agaatttgga acattcaagg caaatgacaa catcaattta caagtaaagg caggagaaat
    27001 tcatgcgttg cttggagaaa acggtgctgg caaatctaca ttgatgaacg tgctttccgg
    27061 attattagag ccgacatcag ggaaaatttt gatgcgtggg aaagaagtaa agatcacaag
    27121 tccgaccaaa gccaaccaat tagggattgg gatggtccat cagcacttta tgcttgttga
    27181 tgcctttact gtaacagaaa acatcgtgtt gggaagcgag cctagtcgcg cagggatgct
    27241 tgaccataaa aaagcacgaa aagagatcca aaaagtttct gaacagtatg gattgtcagt
    27301 caacccagat gcttacgttc gtgatatttc agttggaatg gaacaacggg tagaaatttt
    27361 aaaaacactt taccgaggag cagatgtact gatttttgat gagccgacag ctgtattgac
    27421 ccctcaagaa attgatgaat taatcgtgat catgaaggaa ttagtcaaag aaggcaagtc
    27481 gatcattttg attacgcata agttagatga aatcaaagca gtagctgacc gctgtacagt
    27541 tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa gacgtaacct cacaacaatt
    27601 agccgatatg atggttggaa gaacggtttc attcaaaacg atgaaaaaag aagcgaagcc
    27661 tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa gaaaatcgtg gattagaagc
    27721 cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta cttggtatcg ctggaatcga
    27781 tggaaacggg cagtcggagt tgatccaagc tttgactggt ttgcgaaagg cagaaagcgg
    27841 acatatcaag ctaaaagggg aagacatcac taataaaaaa ccccgaaaaa tcactgaaca
    27901 tggtgtagga cacgtgccag aagaccgtca taaatacggg ttagtcctag atatgacatt
    27961 atctgaaaat atcgcactac aaacctatca tcaaaaacct tacagtaaaa acggcatgct
    28021 gaattattca gtaatgaatg aacatgccag agaattgatc gaagaatatg atgttcgaac
    28081 aacgaatgaa cttgttcccg caaaagcttt atcaggcgga aatcagcaaa aagcaattat
    28141 cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt gcaaatccaa ctcgtggact
    28201 ggatgtaggt gcgatcgaat ttattcataa acgtctgatc gaacaaaggg acaaatacaa
    28261 agcagtgtta ctgatcagtt tcgaattaga agaaatttta aatgtttcgg atcgtattgc
    28321 tgttatccat gaaggagaaa ttgtcggtat cgttgatccg aaagaaacat ctgaaaatga
    28381 attaggtcta ttgatggcgg gctatacctt agaagaagca cgaaaagagt tagaaaaggg
    28441 ggctggcgca catgaatgat cgcagcgaaa aattccgtaa tttattagtg cctgtacttt
    28501 cagttgtttt aggattgatc ttaggcgcga tattgatggc tgcttttggt tttcagccca
    28561 tccaaggtta ttcttctatg ctagatgcag cccttggttc gcaaagaggg ataggtgaaa
    28621 cgttaaggca agcaacgccg ttgattttta cagcattagg tttttctgta gctaactcag
    28681 ctgggttttt caatattggg ctttctggac aagcactttg cgggtggatc gtcagtgtct
    28741 gggtggcact tgcgtttcca gatctgccaa aagttgtttt gcttccgtta tgcgtgatct
    28801 taggtgcctt agctggtgcg atggcagcgg ctgttccagg tttacttcga gcattttttg
    28861 gaacaagtga agtgatcgta acaatcatga tgaactatat cttattatac gtaagcacat
    28921 ttgctttaca tgaagtgatg cctgaaagct atcgctcaag tttggactct tccaatatga
    28981 tcagtcaaaa tgcctcactg cggttaccat ggttaacaca agcttttggc ggctctcgcg
    29041 taaactcagg attattttta gcaatcatcg cgcttatttt cgtttggctg ctgatgaaga
    29101 aaacgacttt aggatttgaa atccgttctg ttggattgaa tccttttgct tctgagtatg
    29161 caggaatgag tagtaaacgt acgatcgttt tgtcgatggt catttctggc gctttggcag
    29221 ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa cttctttgtt caaacgactt
    29281 cgctatctat tggatttgac ggaatggctg tttccttgct tggttctgga tcagcaatcg
    29341 gtattctttt atcagcgatc ttgttcagta ttttgaagat cggtggactt ggcatgcaga
    29401 caggagcagg tgttccgttt gagatcgtca atgtatcgat tgctttgatt atcttctttg
    29461 tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt cttccaaggg aaaaaacaag
    29521 aagagatcgt tgcgacaata gaatcgaaac caacgaatca aaaccatgaa gggggcgaac
    29581 tataatgtcg actatcgaat taattgcctt gatccttact tctacactgg tttattcaac
    29641 accgctaatt ctaacgtcac taggcggaac tttttctgaa cgaagcggga tcgtaaacgt
    29701 agggctagag ggaatcatgg tcatgggtgc ttttagttcc atcgttttca acttgacgat
    29761 gagtccatca cttggttcta tgacaccatg gatcgctatt ttagtgggtg gcgtcgtagg
    29821 tatcctattt tctctgattc acgcagtagc aacagtcagt ttgcgtgctg accatattat
    29881 cagcgggaca gtaattaatc tgatggcacc tgctttaggt gttttcttga tcaaagcatg
    29941 gtatggtaaa ggtcaaactg ataacatcac gcagaatctg gggtattttt ctttcccagg
    30001 attagcagat attccggtca ttggaccaat tttctttaaa aatacattct tacctgctta
    30061 ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc ttcaagacga aattcggctt
    30121 gcgcctccgt tcagttggtg aaaatcctca agctgccgac acattaggta tcaatgtata
    30181 tgctatgcgt tattcaggcg tactgatttc tggcttgtta ggcggtatgg gcggtgctgt
    30241 ttttgctcag tcgatttccg gtaacttttc agctggtacg atcgttggac aagggttcat
    30301 ctccatggct gctatgatct ttggtaagtg gaatccttta ggggcaatgg gtgcctcatt
    30361 gttctttggt tttgctcaaa gcttgagtat cattggcgca caattaccag ttatttcttc
    30421 gattccgcca gtattgctgc aaattgctcc atatttgctg acaatcattg tgctggttgt
    30481 tttcttaggg aaagcttctg gtccaaaagc aaacgggaag aactatatca aatcaaaata
    30541 atcttttagc gaataaaaag ggtgggttac gggaagtgtt tttcgtctcg ccctttttgt
    30601 tttaaaggca ataaaaataa aaagaaagaa ggaataatca tgtttaaacg cgtacatctg
    30661 atcgtcatgg attcagtagg aattggagaa gcaccagatg ccgataagtt cggtgatgtt
    30721 ggttctgata cattaggaca cattgcgaaa gaagcaggat tgaacgttcc acatttagag
    30781 cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg aatcagtgaa agatcatcaa
    30841 ggctatgcga cgaaattaga agaagtttct gtagggaaag atacgatgac aggccactgg
    30901 gaaatcatgg gattgaatat caaaactcca tttcgtgtgt ttcctaatgg attccctgat
    30961 gatctgatca aacaaatcga agaattttct ggccgtaaag tcgtatgtaa caaaccttat
    31021 agcggaacag ctgttattga cgattacggt gaacaccaaa tgaaaacagg cgatttaatt
    31081 gtatatactt ctgccgatcc tgtccttcag atcgcggcac atgaagaaat cattccttta
    31141 gaagaattat atcggatttg ccaattcgtt cgtgatataa caaaagatga tccgtatatg
    31201 attggccgaa tcattgcacg tccgtacgtg ggtgaaccag gagacttcac acgaacaagc
    31261 aatcgccatg attatgcgtt gaatccattc ggacacacag tccttgattc tttgaaagaa
    31321 gcaggaaagg acgtgattgc tgttggaaag atcaacgata ttttcaacgg acaaggaatc
    31381 actgaatctg tccgcacgaa aagcaatatg gatggcgttg accagctgct gaaagttatg
    31441 aaaaacgatt tttcaggaat cagctttacc aatttagtag attttgatgc attatacggt
    31501 catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag aatttgactt acgaattcca
    31561 gaattgcttg aagcgatgga agaagacgac ttgctaatga ttacagccga tcacggaaac
    31621 gatccgacgt ttactggtac cgatcatacg cgagaatatg taccgttatt ggtttacagt
    31681 aaaaaaatga aagaacaagg ggcattgcct caaggatatt attcagatat ttcagcaacg
    31741 attgctgaga actttagtgt ttcttcgact gaaaatggcg aaagcttctt gaaattatta
    31801 aaataatctt tttaaatagg agaaagcaaa tgaccaagtt aagcgagatg ttacaagaaa
    31861 cgacccagtt tatccttgat aaaggagtaa aagaaattga ttttggtttg attctaggtt
    31921 caggattagg tgaattagca gatgaaatcg aagatgctgt aatgatttct tatgatgaga
    31981 tcccgttctt tcctgtttcg acagtagttg ggcatgcagg aaagctagtt tatgggtctc
    32041 tggcaggcaa gaaagtgtta gccatgcaag ggagattcca ctactatgaa ggtcattcca
    32101 tgcaaacagt gacctatcca gtacgtgtga tggccggact aggggcccat tcagtcattg
    32161 tgactaatgc atgtggtggt gtcaacgaat catttgtacc aggagatttg atgctgatta
    32221 ccgatcatat caattttact ggtgaaaatc ctttgatcgg tccgaatgaa gatgcaatgg
    32281 gccctagatt tccagatatg agtcaagctt atacgcctga ctatcaagca acagcaaaag
    32341 cagcagcaga aaaactaggt ttggatctta aagaaggcgt atatatgggc tattctggac
    32401 caacttatga aacgcctgcg gagatccgaa tgtctcggac aataggagcc gatgcagtag
    32461 ggatgtcgac tgttccagaa gtcatcgtag cagctcacag cggattaaaa gtgttaggaa
    32521 tctcttgtat taccaactta gcagcaggta tgcaagcgaa tctgagccat gaagaagttg
    32581 tagaaacaac tcagagagtc aaacaatctt ttaaagcatt ggttaaagaa acattgacat
    32641 tattgtaata ggaggaacaa taaaatgagt gtgcatattg aagcgaaaga aggcgagatc
    32701 gccgataaga ttttacttcc gggagatcct ttgcgagcta aatatattgc ggagactttt
    32761 ttggaagatc cagtttgtta caatcaggta cgcggtatgt taggctttac cggcaaatat
    32821 aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa tgccatcagc caccatctat
    32881 gcccatgaat tgatccagtc gtatggtgta aagaaattga ttcgagtagg tacatgcggt
    32941 gcattgtcaa aagacgtcca tgttcgtgat ttagtactag cacaaggtgc agcgaccagt
    33001 tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc ctccaatcag tgatttcaat
    33061 ctattactga aagcatatga gatagctaaa gaaaagggct atacggttca tgtaggaaat
    33121 gttctttcgg aagattcttt ctacaaagat gatttgacag agacgttcca attagctgaa
    33181 cttggcgttt taggagtgga aatggaagca gcggctcttt attacttagg cgcgaaatac
    33241 catgtgcaga cattaagttt gatgaccgtt agcgaccatt tgatcaccgg tgaagaaaca
    33301 acagctgcag aacgtcaatc tacgttcaat gaaatgatcg aagtaggatt ggaaacagcg
    33361 atagcagaat aagaaggaaa tgaaaaagct gccctgcatt aagtaataag aacatccaag
    33421 caaaaatagc tcctcatgtt tttgacttgg ctggacttat tattgcaaat gtaagctttt
    33481 gaacaccgtt taccaagagg ttgtgaatct gccgtttaac tctgagtcac aaggaacaat
    33541 ttcaaaaaac agcttttcat gtttgatgaa tattgtgact tgtgaccgag aagttggcag
    33601 gagaaaaccg tttatacgaa aaaagggact gtgacaaatc gtgtcacagt ccctttttta
    33661 tagtgttttt tataggtagt attttttagc aactgttaag tcatcattta attcataaac
    33721 aagtggttga cctgttggaa tttcaagatc catgatgtct tcgtcagaga taccttcgat
    33781 atgtttagct agggcgcgta atgagttacc atgtgcagct actaaaacag ttttgttgtc
    33841 tagtaatgct ggagcaattt catcttgcca gaatggcaaa gcgcgttcta atgtcacttt
    33901 caagttttct ccaccaggaa tatcgcgttt gtctaacatt gcgtaacgac ggtcatttgc
    33961 tgcagaacct tcgtcagttt cttccattaa tggaggaaga gtatcgtaag aacgacgcca
    34021 gatgtgcact tgttcgtcgc cgtatttttc agctgtttct tttttgttca aaccttgtaa
    34081 tttaccatag tgacgttcgt ttaagcgcca tgatttgatt tgtggtaccc aaagttgatc
    34141 tgaatattct aagatcaagt tacatgtttt gattgcacga gttaaaacag aagtgtaagc
    34201 aacatcaaat tcgattccag cttctttgat tttgcgtccg ccttcttttg cttcttcgat
    34261 tccttctggt gctagattta catcagccca accagtaaat tggttcaatg cattccattc
    34321 actaagaccg tgacgagaaa aaactaattt tggcatgttt agctctcctt ttaagatagg
    34381 tttatatttc tgaaattttc agttctgttt tattgtacaa ttttttggaa gagatttcca
    34441 tcgaaaaatt agataagatt ctatgagaaa acaagtagag aatataaaaa aacgaacagt
    34501 gcccacgcaa ctgttcgttt ttaggtatta gatgcataat tgctcgattt ctttttcagg
    34561 taaattgata tatttataac atgttccaac tgaaacaccg cattttgaag aaataaattg
    34621 gatcgtttct tttttttcat aatagagacg tcggattttt ttgatcgttt ttgcatcgat
    34681 ttttggtctt ccgccgattt ttcctttttt acgagcttca tctaatccaa ctaatgtacg
    34741 ttctttgatc aatgcgcact ccatgtttgc taggttttcc attaattgga aatagatttt
    34801 tcccatttcg cgcgtatcga ttccttcatc aagactaatc aagtgcagcc cgcgatcttt
    34861 gaataattgc gtgagttctg ttaattgccg cgtagatttg cctaatcgat gaagttggca
    34921 aatgactagt gcatcgcctt gttgcatgtc agcgatcact gactccaaat gaacagcagt
    34981 agaatcattt tgttccactt catatgtctc atggaaaatt tcttgacaac caaagtcaga
    35041 taattgatca acctgagttg ttaaatcaac gtcatttatg gttgtgcgtg cataaccaat
    35101 aattttcatg gtgattcctt tctagcagtg attttctaac tggatataac agtaaaaatg
    35161 tagcataaag tacgtcaaaa agatagtttt ttcgcaaatt ttccgctgtc tttttttatt
    35221 ggatgatcaa gcagtttttc tttatttacg acggattgcg tcaagaatct caacgccttt
    35281 ttctgagccg acaactactt tagaaaccat gtttaggaaa agcccatgtt ctactacccc
    35341 aacaagttca tctaaatagg tagctaagct ttctggctgt tcgatgactt ctagatgcag
    35401 atcaatgatg taatgaccac catctgtggt taagacttct ccgttttcgt ctgtacgcaa
    35461 gacgggttgg aatctttttt cttcaaaaat atgaagtagc tgttgggagc cataagggat
    35521 cacttcaact gggagtggga acttcccaag tttatcgact aatttagaag aatcaacgat
    35581 ccaaatcgtt tcttttgagt acgtagcgac tattttctcg aaaagcaaag cagcgccgcc
    35641 gcctttgatc ccttgaaaat cagcactgat ttcatcagca ccgtctattg tcaaatcgac
    35701 tacggggact tcatcaatac tctttaacgg tattcctaat ttttccgctt gttcttttgt
    35761 cgcatttgaa gtagtaactc ctgtgatacg taaaccttct tcacgcatac ggcgaccaat
    35821 ctcttctacc atataatagg cggttgaacc ggtcccgaga cctacgatca tcccgtcctt
    35881 tacgaatttc gcggcttcaa tgccagctaa ttgttttaaa ttcatctttg cgtccacctt
    35941 tttttagttt gagcatcgtg ctttcctcac tattttagcg tgatttacgg taaaaagata
    36001 ccattctttt ttattccaat aaagcttttt caaaaaaaat tgcatctctt gttgacatgt
    36061 tttttcattc gtgatattct aacaaaggtg ctttatctac aggtttctgt gaagaaacgt
    36121 gctgactgtt tatcaaagca tatttgataa ggatgcagac attgcattta ttttttatca
    36181 caaaaaaaga accacctgga tgtgtggaac tagacgcaaa tcgtgggaag gaggaaacaa
    36241 ggaatgccta caattaacca attagtacgt aaacctcgta aatcaaaggt ggaaaaatct
    36301 aattcacctg ctttgaacaa aggatataac agctttaaga aaactcaaac taacgtaaac
    36361 tcacctcaaa aacgtggggt agcaactcgt gtgggtacaa tgacacctaa aaaaccgaac
    36421 tcagctttac gtaaatatgc acgtgttcgt ttgtcaaact taattgaagt tactgcttat
    36481 atcccaggga ttggtcataa cttacaagaa cacagtgttg tattattacg cggtggtcgt
    36541 gtaaaagact taccaggggt acgttaccat atcgttcgcg gtgctttaga tactgctggt
    36601 gttaacgacc gtaaacaaag ccgttctaaa tacggaacta aaaaacctaa agcttaattt
    36661 taattattaa acaaatgaaa cttgcttcta ctatatagaa gtaattacta tgaacaatat
    36721 ttcggaagga ggagttacgg atgccacgta aaggtcctgt tgcaaaacgt gatgttttac
    36781 cagatcctat ttataactca aaattagtaa ctcgcttgat caaccgtgta atggttgacg
    36841 gaaaacgcgg gattgcagct aacattatct ataatgcctt tgacttgatc aaagaatcta
    36901 caggtaacga tccattagaa gtgtttgaac aagcaatgaa aaacgttcaa cctgttcttg
    36961 aagttaaagc acgtcgtgtt gggggttcaa actaccaagt accagttgaa gttcgccctg
    37021 aacgccgcgt tactctaggt cttcgttggg tagtaaacta cgctcgcttg cgcggtgaac
    37081 acacaatgga agaacgctta gcaaaagaaa tcatggatgc tgcaaacaac acaggtgctt
    37141 ctgttaaaaa acgtgaagac actcataaaa tggctgatgc caaccgtgcg tttgctcact
    37201 atcgctggta agattctctc tgtttggtcg gcttttataa gtcgacctca gatagtgtcc
    37261 ttatttttag caactagata gtaaagagag gagaaacaag gagaatgacc agagaatttt
    37321 ctttacaaaa cactcgtaat atcggtatca tggcccacat cgatgctggt aaaacgactg
    37381 ctactgaacg tatcttgtac tatactggta aaatccataa aattggtgaa actcatgaag
    37441 gagcttcaca aatggactgg atggaacaag aacaagaacg tggtattacg atcacttctg
    37501 ctgctactac agcacaatgg aagggtcacc gaatcaacat catcgacaca ccaggacacg
    37561 tagacttcac agttgaagtt gaacgttcat tgcgtgtact tgatggtgct gtaactgttc
    37621 ttgatgcaca atcaggtgtt gaacctcaaa ctgaaacagt ttggcgtcaa gcaacaactt
    37681 atggtgtacc tcgtatcgta tttgcaaaca aaatggacaa gatcggtgct gacttcttat
    37741 attcagtatc aactttacat gaccgtttgc aagcaaacgc tcacccaatc caattaccaa
    37801 ttggtgcgga agacgacttc acaggaatta tcgaccttgt aacaatgaag gctgaaatgt
    37861 atacaaacga tcttggaaca gagatcgaag aaacagaaat tcctgaagaa taccgcgaat
    37921 tagctgaaga atggcgcgaa aaattggttg aagctgtagc tgaaactgat gaagaactta
    37981 ctttgaaata cttagaaggt gaagaaatca ctgaagctga gttaaaagaa ggtatccgcc
    38041 gcgcaacagt taacgtagaa ttctacccag tactatgtgg ttcagcattt aagaacaaag
    38101 gggttcaatt actattggac gctgttcttg attacttgcc atcaccgtta gatatcccag
    38161 ctatcaaagg gattgaccct aaaactgatg aagaagtaga acgtcctgca gacgacagcg
    38221 ctcctttctc agctttagca tttaaagtta tgactgaccc attcgtaggt cgtttaactt
    38281 tcttccgtgt gtactctggt gttttacaat caggttcata cgtacaaaac gcaacaaaag
    38341 gcaaacgtga acgtgttggt cgtatcctac agatgcatgc caactctcgt tcagaaatct
    38401 ctgaagttta cgctggagat atcgctgctg ctgttggttt gaaagacaca actactgggg
    38461 acacactatg tgatgaaaag agtctagtta ttcttgaatc catggaattc ccagaaccag
    38521 ttatccaagt cgctattgaa cctaaatcaa aagctgacca agataaaatg ggtgtggctt
    38581 tacaaaaact atctgaagaa gatcctactt tccgtgctga aacaaacgtg gaaacaggcg
    38641 aaacaatcat cgctggtatg ggtgaacttc acttagatat catcgttgac cgtatgcgtc
    38701 gtgaattcaa agttgaagct aacgtaggtg cgcctcaagt atcttaccgt gaaactttcc
    38761 gtgctggcac tcaagccgaa ggtaagtttg tacgtcagtc tggtggtaaa ggtcaatacg
    38821 gtcacgtatg gattgaattt acaccaaatg aagaaggtgc tggtttcgaa tttgaaaatg
    38881 cgatcgtcgg tggggttgtt cctcgtgaat acattccagc tgttgaaact ggtttgaaag
    38941 atgctatgga aaatggtgtc ttagctggct atccattagt agatatcaaa gctaaacttt
    39001 acgatggttc ataccatgat gtcgattcaa atgaaactgc cttccgtgtt gctgcttcta
    39061 tggcattacg tgcagcagct aagaaagcta atccagtaat ccttgaacca atcatggctg
    39121 tagaagttgt tatccctgaa gattatttag gtgatgttat gggtcacgta actgctcgtc
    39181 gtggacgtgt tgaaggtatg gaagctcgcg ctggcggcca acaagttgtt cgtgcgatgg
    39241 ttccacttgc tgaaatgttt ggttatgcta caactcttcg ttctgctact caaggtcgtg
    39301 gtacatttac aatgacattt gaccactacg aagatgtacc aaaatcagta caagaagaaa
    39361 tcattaagaa aaacggcgga aaagctgaat aatttcttaa aaccggatag tcctgcaaag
    39421 agattatcca aagagactat atttttaata tagtttcgtg taaaataatt atcgatgata
    39481 tgggcatgtg gtgtaccttg tgtacatcat atacctatca gacaaataaa aaatatattg
    39541 tatttttagg aggacatttt aaaatggcaa aagaaaaatt tgaccgttct aaaccacacg
    39601 ttaacattgg tactatcgga cacgttgacc atggtaaaac tacattaaca gctgcaatca
    39661 caactgtact atctaagaaa aacggcggcc aagctatggc ttacgatcaa atcgatggtg
    39721 ctccagaaga acgcgaacgc ggaatcacaa tctcaacagc tcacgttgag tatgaaacag
    39781 atacacgcca ctacgctcac gttgactgcc caggacacgc ggattacgtt aaaaacatga
    39841 tcactggtgc tgctcaaatg gacggagcta tcttggtagt ttctgctgct gacggcccaa
    39901 tgcctcaaac tcgtgaacac atcctattgt ctcgtcaagt tggtgttcct tacatcgttg
    39961 tattcttgaa caaagtagac atggttgatg acgaagaatt actagaatta gttgaaatgg
    40021 aagttcgtga cctattaaca gaatacgaat tccctggtga cgatgttcct gtagttgctg
    40081 gatcagcttt gaaagctcta gaaggcgacg cttcatacga agaaaaaatt cttgaattaa
    40141 tggctgcagt tgacgaatac atcccaactc cagaacgtga caacgacaaa ccattcatga
    40201 tgccagttga agacgtgttc tcaattactg gacgtggtac tgttgctaca ggtcgtgttg
    40261 aacgtggaca agttcgcgtt ggtgacgaag ttgaagttgt tggtattgct gaagaaactt
    40321 caaaaacaac agttactggt gttgaaatgt tccgtaaatt gttagactac gctgaagctg
    40381 gagacaacat tggtgcttta ctacgtggtg ttgcacgtga agacatccaa cgtggacaag
    40441 ttttagctaa accaggtaca atcacacctc atacaaaatt ctctgcagaa gtatacgtgt
    40501 tgacaaaaga agaaggtgga cgtcatactc cattcttcac taactaccgt ccacaattct
    40561 acttccgtac aactgacgta acaggtgttg ttgaattacc agaaggaact gaaatggtta
    40621 tgcctggcga caacgtaaca atggaagttg aattaatcca cccaatcgct atcgaaaacg
    40681 gtactaaatt ctcaatccgt gaaggcggac gtacagttgg tgccggtgtc gttacagaaa
    40741 tcaaagctta attcacttaa gttttaaagt aaagcaacat ttattcggac gtaatcgctc
    40801 ggaacgaagg tcttaggatc tttgttccga gcttttttat ttattgcagg atcaggaaaa
    40861 aagacaggag tattataaat agaagaaaca cgaaataaaa gagtcagtat tttctaaatg
    40921 aaactttatg aaaacaaaat gttttttaca agaaaaagcc ttgctttgtg agtttatata
    40981 tattataatg acaaaggtgc gtttacttta gtgaattgca cagacgtaat cagaatgatt
    41041 tcgtcggcta agaaacgaga ggttgcgaca cgcccggacg ctttgccacg aacgagcgtg
    41101 acggaaattt tcgtggagct atgtctactt ttcaaaatag gcgaaggagg gaacaagatg
    41161 gcaaaacaaa aaattcgtat ccgtttaaaa gcgtatgaac accgtatttt agatcaatca
    41221 gcggataaaa tcgtggaaac tgcaaaaaga actggagcta gcgtgtctgg tccaattcca
    41281 ttaccaactg aacgcagtct ttacacaatc atccgtgcga ctcataaata caaagattca
    41341 cgcgaacaat tcgaaatgcg tacacacaaa cgtcttatcg acattgtgaa cccaacacca
    41401 aaaactgttg atgctttgat gaagctagac ttaccatctg gtgtaaacat cgaaatcaaa
    41461 ttataaaact aaaacaaaaa taatggaggt gtactcatga ccaaaggaat cttagggaaa
    41521 aaagtgggaa tgacacaaat cttcactgaa tctggtgaat taattccagt aactgttgta
    41581 gaagctactc caaacgtagt actacaagtg aaaacaatgg aaacggatgg ctacgaagct
    41641 attcaagttg gttaccaaga tatgcgtgaa gttttatcaa acaaacctgc gaaaggtcat
    41701 gttgcaaaag caaacacggc tcctaagcgc ttcattcgtg aattcaaaaa tgttgagcta
    41761 ggagaatatg aagtaggaaa agaaattaca gtagatgttt tccaagcagg agacattatt
    41821 gatgtaacag gtactacgaa aggtaaagga ttccaagggg ttatcaaacg ccacggacaa
    41881 agccgcggac caatggctca cggttctcgt taccatcgtc gtcctgggtc aatgggtcca
    41941 gttgcaccta accgtgtatt taaaaacaaa cgtcttgctg gccgtatggg tggcaaccgc
    42001 gtaactatcc aaaacttgga agttgtacgt gtcgatgcag aaagaaatgt tatcttgatc
    42061 aaaggtaatg ttcctggagc taaaaaatct ttaattacta tcaaatcagc tgtgaaagct
    42121 aaataattgt aggaagaaag gaggaactaa ggaatgccga atgtagcatt attcaaacaa
    42181 gatggaagcc aaaacggtga aatcacactt aacgaagaaa tcttcggaat tgaacctaat
    42241 gaaagtgttg tttacgatgc aatcgtaatg caacgtgcgt cattaagaca aggaacacac
    42301 gcggttaaaa accgtagcgc tgttcgcggc ggcggacgta aaccatggcg tcaaaaagga
    42361 acaggtcgtg cacgtcaagg atctatccgc tcaccacaat ggcgtggagg tggcgtagtc
    42421 tttggaccaa caccacgttc ttacagctac aaacttccta aaaaagttcg tcgtttagca
    42481 atgaaatctg tattgtcaga aaaagttgct gaaaacaact tggtagcaat cgaaggcttg
    42541 aacttcgacg caccaaaaac aaaagaattc aaacaagttc ttgctaactt atctatcgac
    42601 tctaaagtat tggttgttct agaaaaaggt aacgactttg ctgctttatc agcacgtaac
    42661 ttaccaaacg tttctgtagt aacttctgat aatgtgagtg tgctagacgt tgtatcaaat
    42721 acaaaagtgt tagcaacaca aactgctctt actcaaattg aggaggtgct tgcataatga
    42781 acttactaga cgtaatcaaa cgcccagtga tcactgaaaa atcaatgctt gccatggatg
    42841 acaagaaata cacttttgaa gtggacactc gcgcaaacaa aactttagta aaacaagcgg
    42901 tagaagctgc ttttgacgtt aaagtcaaaa acgtgaacat cgtgaacgta cgtgcgaaat
    42961 tcaaacgtat gggcaaatat gcaggatata caaaaaaacg tcgcaaagcg atcgttacat
    43021 tgactgaaga ttcaaaagaa atccaattat tcgaagctgc tgaataagca ctaatagata
    43081 actcattaaa ttaggaggga aaaacgtggc gattaaaaag tacaaaccta cctcaaatgg
    43141 tcgtcgtaac atgacaggtt ctgattttgc tgaaatcaca acatcaacac ctgaaaaatc
    43201 attgttacaa ccattgaaaa accatgctgg acgtaacaac aacggccgca tcactgtacg
    43261 tcatcaaggt ggcggacaca aacgccaata tcgcgtgatc gacttcaaac gtaacaaaga
    43321 taacgttgtt gcaactgttc aaacgatcga atatgatcca aaccgttcag ctaacatcgc
    43381 gttagtacac tatgaagatg gagtgaaagc ttacatctta gcacctaaag gactagaagt
    43441 gggtatgaaa cttgtttcag gtccagaagc agatatcaaa gtcggaaatg ctcttccatt
    43501 agaaaacatt ccagttggta ctgttatcca caacattgaa atgaaacctg gtaaaggtgg
    43561 acaattgatc cgttctgctg gtacaagtgc tcaagtactt ggtaaagaag gcaaatacgt
    43621 attgatccgc ttgaactctg gtgaagttcg tatgatctta gctgcatgcc gtgctacaat
    43681 cggttctgta ggtaacgaac aacacgaatt aatcaacatc ggtaaagctg gacgctctcg
    43741 ttggatgcgt aaacgcccaa ctgtacgtgg tagcgtaatg aaccctaatg atcacccaca
    43801 cggtggtggt gaaggtaaag ctcctatcgg acgtaaagca ccagtttctc cttggggtca
    43861 accagctctt ggttacaaaa ctcgtaacaa aaaagctaaa tcagacaaac ttattgttcg
    43921 tcgtcgcaaa aataaataat tactttgacc atgtgtcgca cattttgaga ggaggttcac
    43981 catgggtcgt agtttaaaga aaggaccttt tgtcgatgag catttaatga aaaaagttga
    44041 agctcaagca ggggttgaaa agaaaaaagt tatcaaaact tggtcacgcc gttcaacagt
    44101 tttcccaagt tttgttggat ataccatcgc agtttatgat ggacgtaaac atgtaccagt
    44161 ttacatccaa gaagacatgg taggacacaa attaggtgaa tttgcaccta caagaactta
    44221 tcgtggacat gctgctgacg ataagaaaac gaaacgctaa tttgagggga ggataaatcc
    44281 aaatggcaga acaaatcaca tcagctaaag caactgcaaa aacagttcgc acttcacctc
    44341 gaaaagcccg tttagtaatt gaccttatca gaggtaaaag tgtcgcagat gcaatttcaa
    44401 tcttgaaatt cacaccaaac aaatctgctg gaatcattga aaaagtattg atgtcagcag
    44461 ttgcgaatgc agaaaataac tttgacttag atgttgaaaa cttggtagta agcgaagctt
    44521 ttgttaacga aggacctaca atgaaacgtt tccgtcctcg tgcaaaagga tcagcttctc
    44581 caatcaacaa acgtacaagt catatcacgg tagtcgtatc agaaaaataa ggagggataa
    44641 tcagtgggtc aaaaagtaca tccaattgga atgcgtgtag gcatcatccg cgactgggat
    44701 gctaaatggt atgctgaaaa agagtatgct gagttcttac acgaagattt aagaatccgt
    44761 aaatttattt caactaaact tgctgatgct gctgtatcaa cagttgaaat cgaacgcgca
    44821 acaggtcgcg taaacatttc aattcacaca gctaaaccag gtatggttat tggtaaaggc
    44881 ggttctgaag tcgaaagcct aagaaaagaa ttaaacaaat taactggtaa aagaatccat
    44941 atcaatatcg tggaaatcaa aaaaccagat ctagatgcaa aattagtagg tgaaggaatc
    45001 gcacgtcaat tagaaaaccg tgttgctttc cgtcgcgctc aaaaacaagc catccaacgc
    45061 tcaatgcgtg ctggcgctca agggatcaaa actcaagtat ctggtcgtct aaacggagca
    45121 gatatcgctc gttcagaagg atactcagaa ggaactgttc ctcttcatac tttacgtgcg
    45181 gacattgatt acgcatggga agaagcagat acaacatacg gaaaactagg agttaaagtg
    45241 tggatctatc gtggagaaat tcttccaact aaaaaaaaca ctgagaaagg agggaaataa
    45301 tcatgttagt acctaaacgt gtaaaacacc gtcgtgaatt ccgcggaaaa atgcgcgggg
    45361 aagctaaagg cggaaaagaa gtagcattcg gtgaatacgg tttgcaagct gttgattcac
    45421 attggatcac aaaccgccaa atcgaagctg ctcgtatcgc aatgactcgt tacatgaaac
    45481 gtggtgggaa agtatggatt aaaattttcc ctcacaaatc ttatactgcc aaagcaattg
    45541 gggtacgtat gggttctggt aaaggggcac ctgaaggatg ggttgcacca gtaaaacgtg
    45601 gtaaaatcat gtttgaaatc gcaggcgttc ctgaagaagt agctcgtgaa gcgttacgtc
    45661 tagcttctca caaattacca atgaaaacta agatcgtaaa acgtgaggaa atgggtggtg
    45721 aatcgaatga aggttaaaga aatcagagaa ttaaccactg ccgaaatgct tgatcaagaa
    45781 aaacaattaa aagaagaatt gtttaatctt agattccaat tagcaacagg tcaattagaa
    45841 aacactgcac gtattaaaga agtacgtaaa tcgattgcac gcatcaaaac tgtgttgcgt
    45901 gaacaagcta agtaattatg gaaggaggcc attaagcgta tgactgaagg aagaaatcaa
    45961 cgcaaagttt atcaaggtcg cgtggtttca gacaaaatgg ataaaacaat taccgttgct
    46021 gtcgaaacaa agaaaaacca ccctatctat ggcaaacgca tgaactattc taagaaatac
    46081 aaagtgcatg atgaaaacaa cacagcaaaa gttggcgaca tcgtgagaat tatggaaact
    46141 cgtccattat cagctacaaa acgtttccgt ttgttggaag tagtcgaaga agcagttatt
    46201 atctaataac acgagatttt cctatataga ttgaatgcaa aatctgaaag gaggatacac
    46261 aacgtgatcc aagcagaaag tcgtttaaaa gtcgctgata actcaggcgc acgtgaaatt
    46321 ttgacgatca aagtccttgg tggatctggt cgtaaaactg ctaacatcgg tgatgtgatc
    46381 gttgctacgg ttaaacaagc aacgccaggt ggggttgtca aaaaaggtga cgtcgttaaa
    46441 gccgttatcg ttcgaacaaa atcaggagct cgtcgtacag acggttcata tattaaattt
    46501 gatgaaaatg ctgcagtgat tattcgtgat gataaaagcc ctcgtggaac acgtatcttt
    46561 gggccagttg cacgtgaact acgtgaaaac aacttcatga agatcgtttc actagcacca
    46621 gaagttttat aatcttgaga cacttatcaa aggaggtgcg aaacagttat gtttgttaaa
    46681 aaaggcgata aagttaaagt tatcactgga aaagacaaaa acaaagaagg cgttgtacta
    46741 gcagcgttcc cgaaaaaaga taaagttatt gtcgaaggtg taaatgtcgt taaaaaacac
    46801 caaaaacctt ctcaagctgc tcctcaaggt ggaattgttg agatggaagc gccaattcat
    46861 gtttctaacg tgatggtggt tgactctact ggtgtagctg gccgagttgg ctacaaagaa
    46921 gtagacggca aaaaagtccg tgtttctaaa aaaaccggtg aagttttaga taaataaaag
    46981 tttaaggaag gagggtctta ctgaatgaac cgcctaaaag aaaaatatct taaagaagta
    47041 actccatcat tgatggaaaa atttaactat agctctgtta tgcaaacacc taaagttgaa
    47101 aaaatcgtca tcaacatggg tgttggtgat gcggtatcaa acgctaaaaa cttagataaa
    47161 gcagttgaag aattaacttt gatcactggt caaaaaccaa tgattacaaa agctaaaaaa
    47221 tcaatcgctg gattccgttt acgtgaagga atgccaattg gtgcaaaagt tacattgcgc
    47281 ggagaaagaa tgtacgaatt cttagacaaa ttggtttctg tttcactacc acgtgtacgt
    47341 gacttccatg gtgtaagtaa aaaagccttt gacggtcgtg gaaactatac tttaggtatt
    47401 aaagaacaat tgatcttccc agaagtagat tatgatttag tagataaagt acgtggtatg
    47461 gacatcgtta ttgtaacaac agcaaactct gatgaagaat ctcgtgagtt gttgacacaa
    47521 ttaggcatgc cattccaaaa ataattaaag gaggcgaact acgtggctaa aaaatcaatg
    47581 attgctaaaa acaaacgtcc tgcaaaattt tcaacacaag cttatactcg ttgcgaacgt
    47641 tgcggacgtc cacattcagt ttatcgtaag ttccatcttt gccgtatttg cttccgcgaa
    47701 cttgcctata aaggtcaaat tcccggcgtg aagaaagcta gctggtaaaa agtaaattcg
    47761 cataagaagg aggtaaaaga tcaatggtca tgacagatcc aattgcagat tttctaactc
    47821 gtatccgtaa cgcaaacatg gttaaacatg agtctttaga agtacctgca tcaaaaatta
    47881 aacgtgacat cgctgaaatc ttgaaacgtg aaggtttcgt tcgtgatgtt gaatacatcg
    47941 aagatgacaa acaaggcgtg atccgtgttt tcctaaaatt tggtaaaaac ggcgaacgtg
    48001 ttatcacaaa cttaaaacgt atctctaaac caggtttgcg tgcttatgtc aaagctgacg
    48061 aagtaccaaa agtattgaac ggtttaggta tcgcaatcat ttcgacttct gaaggtgttg
    48121 tcactgataa agaagctcgt gaaaaaaata tcggcggcga agttatcgct tacgtatggt
    48181 aatcaagtag aatctacaag gaggtgtctt taagtgagcc gtatcggaaa taaagtcgtt
    48241 gttatccctg aaggagtaac agttactcaa gacggaaaca acgttacagt taaaggacca
    48301 aaaggtgaat tgactcgtac tttttcagca gatatcaaaa tgaatatcga aggaaacgaa
    48361 gtaactttca ctcgtccaaa cgacagtaaa gaaatgaaaa caattcatgg aacaactcgt
    48421 gcgaacttca acaacatggt tgtaggtgtc agcgaaggtt tccaaaaagc gttagaacta
    48481 atcggggttg ggtaccgtgc acaattacaa ggatcaaaac ttgtattgaa cgttggttac
    48541 tcacatccag tagaaatcac accaccagct ggagtaactg ttgaagtacc agctaacaca
    48601 caagtaattg ttaaaggtgc gaacaaagaa gaagttggcg aattagctgc aaacattcgt
    48661 ggaactcgtc ctccagaacc ttataaaggt aaaggtattc gttatgttgg cgaatatgta
    48721 cgccgtaaag aaggtaaaac tggtaaataa tcgtttagaa aaattgcata gaagccagca
    48781 gcaggaaaaa ggcatttggc tgaagtttac cttcaaaaaa atacattttt acttgtgccg
    48841 cagcttctat ttttcgaaac gtatttactg cttgaaatag tagtacaata aaaataaaga
    48901 ggtgacaatt gtgattacaa aaccagataa gaacaaaaca cgtcaaaaga gacatcgtcg
    48961 tgtacgtaac aatatctctg gtactgctga gcgcccacgc ttgaacgttt ttcgttctaa
    49021 caaaaacatc tacgctcaaa ttattgatga cgtagcgggt gtaacgctag caagtgcctc
    49081 taccttggat aaagaaattt caggtggaac aaaaacagaa gcagcacaag ctgtcggtaa
    49141 actagttgct gaacgtgcag ctgaaaaagg cattaaagta gtagtctttg accgtggtgg
    49201 atacctttac catggccgtg tgcaagcttt agctgaagct gctcgcgaaa atggactaga
    49261 attttagaag aaggaggaat accattcatg gtttatatcg atccaaaaca tttggaatta
    49321 gaagaccgcg ttgttgcaat taaccgtgta acaaaagttg ttaaaggtgg acgtcgtcta
    49381 cgttttgctg ctttagttgt tgtcggtgac aaaaacggac acgtagggtt tggtacaggt
    49441 aaagctcaag aagttcctga agcaatccgt aaagcaattg aagatgcgaa gaaaaactta
    49501 gttgaagtac ctatggttgg ttcaacaatc ccacacgaag taatcggtgc ttttagtggt
    49561 ggtagaatcc taatgaaacc tgctgtagaa ggttctgggg ttgctgctgg tggaccagtt
    49621 cgtgccgtat tagaattagc tggggtagca gatatcactt ctaaatcttt aggctcaaat
    49681 acaccaatca acgttgttcg cgcaacagtt gaaggtttga aacaattgaa acgtgcagaa
    49741 gaagttgcag aacttcgcgg caaatcagtt gaagaattaa tcggataagg aggacaacaa
    49801 taatggctga attaaaagtt actttaaaac gcagtattat cggacgtcct caaaaccaac
    49861 gcgatacagt taaagcgtta ggtcttacaa agattaacag ttcagtggtt aagccttcta
    49921 atgaagcaat taaaggcatg atcaatactg tttctcacct agtggacgtt gaagaaattt
    49981 aatttagaaa aatcataact agaacattaa ggaggtgcca aacctatgaa acttcatgaa
    50041 ttaaaacctg ctgaaggttc acgccaagta cgtaaccgtg ttggtcgtgg tacttcatct
    50101 ggtaacggaa aaactgccgg acgcggacaa aaaggacaaa aagctcgttc aggcggcggt
    50161 gtgcgtttag gatttgaagg gggacaaaca ccattgttcc gtcgtttacc aaaacgagga
    50221 ttcacaaacg tgaaccgtaa agactatgca gtcattaatc ttgatgtatt gaaccgcttt
    50281 gaagacggag ctgaagtaac tcctgttgct ttagttgaag ctggaatcgt gaaaaacgaa
    50341 aaagctggaa tcaaagtatt agctaatggg gaactaaaca agaaattaac tgtgaaagca
    50401 gcaaaattct ctaaagcagc tcaagaagca attgaagcgg ctggtggatc aatcgaggtg
    50461 atctaatgtt tagactatta aaagatgctt ttaaagtaaa agacattaga tcgaaaatcc
    50521 tatttactgt atttgtgttg tttgtatttc gcctaggtgc acatattact gtaccaggcg
    50581 taaatgctgc ttcattgcaa aacctttctt ctttgccatt tttcaacatg ttgaacttgg
    50641 taagtggtag tgcgatgcaa aacttttcca ttttctcaat gggggtttca ccatacatta
    50701 ctgcttctat cgtcattcag cttcttcaaa tggacatcgt gcctcgattt gttgaatggt
    50761 cgaaacaagg ggaagttggt cgtaaaaaac tgaatcaagc gactcgatat ctgacattag
    50821 tattggcatt tatccaatct gtcggtatca ctgctggatt caatcaatac gctcaattag
    50881 gtttcgtgaa taatcctaac gtagcaactt acgtaacgat cggtttgatt ctaacagccg
    50941 gtacgatgtt tgttacttgg ctaggagaac agatcacaga aaaaggtatc ggaaatggcg
    51001 tatcaatgat catttttgca ggtatcattt ctagattgcc tgaaagtatc agagaaattt
    51061 atgaagatta ctttataaat attgatcctt cagacatatg gaaatctgct atttttgtgg
    51121 ccattttact agtagcggtc ttgttgatcg tgacattcgt aacatttttc caacaagctg
    51181 aacgcaagat cccgatccaa tatacgaaac gcgtagctgg cgcgcctaca agcagctatc
    51241 tgccgttgaa agtaaatgca gctggagtta ttccagttat ctttgctagt tcgtttattg
    51301 ctacgccaaa tgctgtttta caagcattga gcggtagatt cggttctgaa aactggtaca
    51361 aagtgatgat ggagatcttt aactataata cagcacctgg tgctacgatt tatacgattc
    51421 tgatcgttgc cttcactttc ttctacgcct ttgttcaagt aaaccctgag aaattagcgg
    51481 aaaacttgca aaagcaagga agttatatac caagcgtacg ccctggtaag gggactgaag
    51541 agtatgtctc aagattactg atgcgtttaa gtacagttgg tgcagtcttc cttggtttag
    51601 tggcattgct tccaatcatt gctcaaatgg tttgggatct tccacaatca atcggattag
    51661 gcggtacaag cttactgatc gttatcggtg tagctttaga aactgcgaaa cagttagaag
    51721 gcttaatgct gaaacgtaaa tatgttggat tcattgagta agaaagcgtg ttgaggtttc
    51781 ccctcaacac acgttctcac acatttatta ggagggaaaa caatgaacct cattttaatg
    51841 gggctgccag gcgcaggtaa aggaacacaa gctgaaaaaa tcattgatgc ttatggtatt
    51901 ccgcacatct caacaggaga tatgttccgc gcagcgatgc aaaacgaaac agctcttggc
    51961 ctggaagcaa agtcttatat ggataaaggt gcattagttc ctgatgaagt aacaaatgga
    52021 atcgtgaaag agcgactagc tgaaccagat acagagaaag gcttcttatt agatggcttt
    52081 ccacgtacgc tagatcaagc aaaagctctg gacgcaatgc taaaagattt gaataaaaaa
    52141 attgatgctg tcatcgatat ccatgttggt gaagaaatct tggtcgaacg tctagccggc
    52201 cgatttatct gcagcaattg tggagcaact taccataaaa ttttcaaccc tacaaaagtt
    52261 gaagacacat gtgatcgttg cggtgggcat gaattctatc aaagagaaga tgataaacct
    52321 gagacggtta aaaatcgtct ggctatcaac atcaaaaata gtgaaccaat cttggcttat
    52381 tataaagaac aaggtttgct aaacactatt gatggtgctc gtgaaatcga tgctgtattt
    52441 gcagatgtac aaaaaatcat tgaaaaatag cacgattgcc cgtagccgac ttgcattatg
    52501 cagttactct tgtcaagttc aataaattat gatagaatat gtcagtccga cttctagaga
    52561 atcctctaga tgatccattt tgagaatttt gaggtgggaa ctgcagtttc cgccatttta
    52621 tcgtgtgaaa atgcgaaaca agtacaagga ggtactgtgc gtggcaaaag aagatatgat
    52681 tgaagtcgaa ggtacagtcg tcgaaacttt gccgaatgca atgtttaaag ttgaactaga
    52741 aaacggacac caagttcttg ctactgtttc aggtaaaatt cgtatgcatt acatccgtat
    52801 cttacctggt gacaaagtaa cggttgaatt gtctccatac gatcttaacc gtggccgtat
    52861 tacttatcgc tttaaataat tgtactccgt aaaactacag gaggtattat catgaaagta
    52921 agaccatcag taaaaccaat gtgcgaacat tgtaaagtaa ttcgtcgtaa aggacgcgtt
    52981 atggtgattt gcccagcaaa tccaaaacat aaacaacgtc aaggataatt ggaggtgcta
    53041 taaatatggc tcgtattgca ggagtagata ttcctcgtga taaacgtgta gtagtttcac
    53101 ttacttatat ctatggtatt ggtaacacta ctgctaaaaa gatcttagct gatgctggtg
    53161 tatctgaaga tgttcgcgtt cgtgaattaa cgaatgaaca aacagatgct atccgtgcag
    53221 aagtagataa attaaaagtt gaaggggatc ttcgtcgtga agtgaacttg aacatcaaac
    53281 gtttgatgga aatcggttct taccgtggaa tccgtcatcg ccgtggattg cctgttcgtg
    53341 gacaaaacac gaaaaacaat gcacgtactc gtaaaggccc agctcgcgct atcgctggca
    53401 agaaaaaata attcttaagt gaaggaggtt aaaacttcat ggcagcaaaa aaagtgaatc
    53461 gtaaacgccg tgtgaagaag aatatagaag caggtattgc acatatccat tctacattca
    53521 ataacactat catcatgatc actgatactc acggaaatgc attagcgtgg tcatcagctg
    53581 gttcattagg tttcaaagga agcaaaaaat caactccttt tgccgctcaa atggcagcag
    53641 aaactgctac aaaagcagca atggaacacg gattaaagac tgttgaagta acagttaaag
    53701 gacctggttc tggacgtgaa gcagcaattc gttcattaca agctacaggt ttagaagtga
    53761 ctgcaattcg tgacgtgact ccagttcctc ataatggtgc ccgccctcca aaacgccgtc
    53821 gtgtttaatg agtgccgctc attttgagtt ttatcagtaa cgtcattgaa caagacactt
    53881 ttcgttttga aaggggtaaa gataagaatg attgagttcg aaaaaccaag aatcgcaaaa
    53941 attgatgaag aaaaagatta tggcaagttc atcgttgaac ctcttgaaag agggtatggg
    54001 actactttag ggaattccct acgtcgtatt ttattatctt ctttgccagg tgctgccatc
    54061 actaatattc aaatcgatgg tgtactgcat gaattctcta ccatcaaagg tgttagagaa
    54121 gacgtcactc aaatcatctt gaacattaaa ggcttagcgc tgaaaatgta tggccaagaa
    54181 gaaaaaaccc ttgaaatcga tattaccgga cctgctacag taactgctgg cgatattatc
    54241 gttgatagtg atgtagaaat tcttaacaaa gatatgtaca tctgtagtgt ctctgaagga
    54301 gctacgttcc atgctcgctt aacagtgaaa cctggacgtg gttatgttca agcagatgaa
    54361 aataaaaaag aagatatgcc aattggcgtt cttccagtcg attcaatcta cacacctgtt
    54421 cgtcgtgtga actatcaagt tgagaacaca cgtgttggac accgtgaaga ttttgataaa
    54481 ttgacgatgg agatttggac agatggttca attgaaccgt tggaagcaat gagtttgtct
    54541 gcgaaaatca tgactgaaca tttggatatt tttgtgaact taactgatga agcaaaaaat
    54601 gctgaaatca tggtcgaaaa agaagaaaca caaaaagaaa aaatgttgga aatgacgatc
    54661 gaagagttag acttgtctgt tcgctcttac aattgtttga aacgtgcagg aatcaatact
    54721 gtacaagaac ttacaaataa atctgagcct gaaatgatca aagtccgtaa cttaggacgt
    54781 aaatcattag aagaagttaa agcaaaattg cacgacttag gtttaggttt acgtaaagaa
    54841 gattaaaacc ttttacgaag gagggaaacc aacgtgagtt atcgtaaact aggacgcaca
    54901 tctagccaac gtaaagcgat gttgcgtgat ttaacaactg atttattaat caacgaacgt
    54961 attgtgacta ctgaagctcg tgcgaaagaa gttcgctcaa ctgcagaaaa aatgatcact
    55021 ttaggtaaac gcggagattt gcatgcacgt cgtcaagctg cggctttcgt acgtaatgaa
    55081 gttgccagcg tgcgtgaaga aaatgaggac atcgtcattg aatcagcttt acaaaaactg
    55141 ttcaacgata ttgcacctcg ttacgcagaa cgtcaaggcg gatacacacg cattttgaag
    55201 acagaaccaa gacgcggtga tggtgcacca atggttgtct tagaacttgt ctaaaatcac
    55261 actaataaca tcactttata gatgattctt ttagagtgtt atgatgttgg aagatatttt
    55321 tccgagtcta gctcagcgct gctcctcaag cgaatatcgc ttggggagta agcactcatc
    55381 ataaagtgtt tttttatacc ttcaattacc tgtcatgaca gatatgtttg aaggcataaa
    55441 aaaacatttt aagcgagaaa taattgaaaa ttttgtcttt ttttgatagt gttagtagga
    55501 actttaggat gaagaaggag taatcatgga gccaattatt gaattagaaa agataaatta
    55561 taaataccag ccagatgatc ttcgccccgc attgaaagat gtctccttta caattgataa
    55621 aggtgagtgg atcgctatta ttggacacaa tggttcagga aaatcgacac ttgccaaaac
    55681 gatcaatgga ttgcttctgc cagaatcagg gatcgtgaaa gtgggaaatc aaatattgga
    55741 tgaagaaaat atttggacga tccgacagat ggttggaatg atttttcaaa atccagacaa
    55801 tcagtttgtt ggttcgacag tagaagatga cgttgctttt ggtcttgaaa atcaagggat
    55861 tcccagagaa gaaatgctag tgcgtgtgaa agatgcactt gagaaagtta gaatggctga
    55921 gtttgcttca cgcgagcctg ctcgtttatc aggagggcaa aaacaacgtg ttgccattgc
    55981 cggcgtggtt gccttacgac ctgatatcat tattttagat gaagcaacca gtatgctaga
    56041 tccagaaggt cgtgaagaag tgatctctac gatcaagaag atcaaagaag aaagtcaatt
    56101 gaccgttata tctatcactc atgatattga tgaagcagct aatgccaatc ggatactagt
    56161 gatgagacaa ggcgaacttg tccgtgaagg tacaccaaaa gaaatttttt ctgctggtcc
    56221 tgaactgatc gacttaggtc tagatctacc atttcctgaa aaactgaaga gcgcactgaa
    56281 agaacgtggg gttgatgtgc ccagtgaata tatgacagaa gaaaggatgg tggattggtt
    56341 atggacatcc gttttgaaca agtagacttc acttatcagc cgaatacacc atttgaacaa
    56401 agagccttat ttgacatcaa tatgacgatc aaagaaaaca gttatactgc attagtaggg
    56461 cataccggaa gcgggaaatc aaccttactt cagcatttga atgcgcttgt taagccaaca
    56521 agcggtacag tccatattgg agaacgagat attcagccgg atacggataa taagaattta
    56581 aagcccatcc gaaaaaaagt tggcatcgtc tttcagtttc cagaagcaca gctattcgaa
    56641 gaaacggtag caaaagacat tgctttcggt cctaaaaact ttggtgtcag cgaagaagaa
    56701 gcactagtcc tagcaaaaga aacattagaa caagttgggc tggatgaaag ctatttggaa
    56761 cgttcgccat ttgaactttc aggagggcaa atgcgtagag tagcaatcgc tggtgtgctt
    56821 gccatgaggc cggaagtact tgtattggat gaaccaacgg caggacttga tccccagggc
    56881 agaaaagaaa tgatggagat gttttggcgt cttcataagg aacagcagat cactattgta
    56941 ttagttacgc atttaatgga tgatgtagcc aattttgcag attatgtcta tgtgttggaa
    57001 aagggacgaa tcgttaatag cggggagccg caagaggtct ttcaaaacat tgaatggcta
    57061 aaagaaaaac aactaggcgt acctactgcc accgagtttg cagaagaatt aatggctaaa
    57121 gggatgaact ttgctacctt gcctttgaca gctgaagaat tagcagacgc tatcgtccat
    57181 tatgctggag gaaatgccca tgatgaataa attgatattt ggtcgttata tgcctggaga
    57241 ttccttgatc catcgattgg atccccgagc taaattatta gccagttttt attttatcgg
    57301 aatcattttt ttagcaaata attgggaaac gtaccttttg ttggcatttt tcacattact
    57361 ttctgtcttc ttgtcaaaag tagatttgaa attttttatc cgaggcattc gcccattgat
    57421 ctggctaatc ctcttcactg tagctttgca ggtcttgttt acaagtggcg gagaaactta
    57481 ttggagttgg ggtgttttcc atatcactga atttggtgtg atgaacggcc tctttatttt
    57541 ctgtcgattc gtgttgatca tttttatgtc gactctactc acgcttacta caccgccttt
    57601 ggaattatcg gatgcgattg agtacttgct tcgtccattg aaagccgtac ggttcccagt
    57661 ccacgaaatt tcattgatgc tgtcgattgc tcttcgtttt gtgcctacat tgatggacga
    57721 aacagaaaag atcatgaacg ctcagcgcgc tcgcggtgtt gattttggtg aaggaaacct
    57781 agttcagaaa atgaaagcag tcattccttt gctgattcct ttatttgtca gcagcttcaa
    57841 ccgtgcggaa gatcttgcga ctgctatgga agcaagaggc tacaaaggtg gggaaggaag
    57901 aacgaaatat cgtgtattgc attggcataa tagagacacg atggttatca ttgcttttgt
    57961 attattaact gtgctactga tctttttaag aggataaacg ttcagtgggc cgctatctat
    58021 tcttttcttg ctgatctgtt tgcaagaaag gatgcaagca gtgtatgaca agaaatatta
    58081 gggtctgtgg cagactaagg tcacaggcct ctttctttta tctgaaaaga aagaacgaaa
    58141 aaattttata gaaaaatcat tattccagat aaccttttag gaacaaagga gagaaaaaca
    58201 tggtacgtta caaagcaatc attgcgtacg acggaacaaa ttttaatgga ttccaaaaac
    58261 agccaaatgg gcgtactgtt caagaagaag tagaaaaaac attacaaaaa atggcaaatg
    58321 gaaaagaaat cacggtcttt ggttcgggaa ggacagatgc cggagtacat gcgatcgggc
    58381 aagtaatcca ttttgattat ccagaggagc gtccgttaga acgaatgcgt ttcgcgctag
    58441 atacccagtc accagaggat attgctgtaa gacaagtaga aattgtttca gaagacttcc
    58501 acgcaagata tttggtcaaa gaaaagacgt atcaatttcg agtggatata gggaaaccac
    58561 gcagtccttt tcgacgccat tatgcaagtt attttcctta cccacttgat ttggaaaaaa
    58621 ttcagcgggc gcttcctgat ttattaggga ctcacgattt cacctctttt tgtgcatcag
    58681 gaagctcgat agaggataaa atacgtacga tctacgaggc taagatggag gtaaatgaaa
    58741 caaaagacga attgttgttt acatttaggg gaaatggctt cttgtataag atgatacgga
    58801 tcttagtagg aacgcttttg aaaattggca atggccgatt gcctgaagat agtatcccag
    58861 atattattgc gaaaaaagat cgtaatgcag caggacctac agcacaccct gaaggacttt
    58921 atttgtatga agtgaaatat gaataagagg ttatgataga agtggtcagc ttcaagaaat
    58981 aagaaggtat ttacgaaaat tacttctcaa aattttgcaa aatttcggct tattttcgaa
    59041 gaagctactt ctggaacacc gtttaagaaa gaggtcgtga gcctgtcatt taactctgag
    59101 tcacaaagag caatttcaaa aaacagcttc tcatctttga tgaatatcgt gacttgtgga
    59161 cgaggcgttg ataagtgaat catctttttg ttacctattt tttctgtaac caaaaaacga
    59221 tggaacgttg ttttgattgc ccttggtgcg gacagtctga acaggttcca tcgtttcttt
    59281 attttctacg tcttcttctg tgtgtgtttc gtggttgttc ttctattgct ggatcaatcg
    59341 tgccataaaa ggggcgattg cggtcaaggt accagacata aagaataaac aatgcaatac
    59401 ataggacaaa aaggattgca cctatcgtaa atccttcagg caagtaactg aaagtgacag
    59461 tatgtttacc tgctggaact tttatcatca agaatgcgtc tttgaaattg ctgaccttga
    59521 ctggtttccc atcaatttta gctttccatc ctttgtcata aggaatagtt gtcaccaaca
    59581 tggaatcttc agcggtattt acagtcccag aagcttttct gccagtggct tccatttcga
    59641 cacctttttc tttgatctga ttcattgcgg cttgataggc tacaacatct agaccaacga
    59701 ctttaggctc catgaaactt atttctttcg tcccataaaa acttgcagta aatgtcactg
    59761 ttgtctcttg aggataatag ccaagatcat agtattgacc agaaatgttg atttgcgttt
    59821 ttcgcgatgt accattgaca gtgatcgtcg cactagaact ttctaattgc gcaaaattgg
    59881 ttgggaacaa acttaagtaa gcttgtgtat ttgcaggcac atggacttcc caagtgagct
    59941 cttttggctg gttatctgct gtttctgagt aagtgacgcc agtcgttgtc tttgtgatcg
    60001 tcgtattcaa ctgattcttc aaagtaggtg tatagaatgt aaaatactgt tcatttagac
    60061 cagacaatgt attgatcaag tttgtctgac tggtcaaatt atctgtcact ggctgctcaa
    60121 catcattaac ggacaacggt gcagtaaatg ctagtggcaa tgcattgaca ttctgataca
    60181 gtgtatagtc gccgctttga ccagcttggc ggaagccata tttactgaac gtgctttcgt
    60241 ttttagaaat gttatatttg attcctgtaa acccatccat cagcaaagta ttattgttat
    60301 aacggatatt caaatttgtc cctcttgaac ggaaacctaa tttatccagg taagaggaag
    60361 aattacgatt tcttatagaa gaaaacaaac tgataccact gtaaccatag ttgatcgaat
    60421 cgtttgcaga tactggatcc agattttcca agcggtaaaa cgagtcggaa tctttttttg
    60481 tttcatttac aagagctttc aagtcaggat aaggatcagt atataaactg cgggaagcat
    60541 aattccaatc atcaagaatg ccatggatca tactgttcgt attgaccagt gcttcagcag
    60601 acatgatcaa taataacaat atactcagat gattgaatga aagtttttta tgctgataaa
    60661 atcccacagc aaaagcataa atccctaaga aaaccactgt caatacaaag gaagtcatcg
    60721 tcacataggt gtagcttcct tcaggtttga tgccccatgc caccgcaaag agagcagcta
    60781 cgaccaaaat gattcctaac aacagcccac catcgtcttg ttctatcttt tcccatcctt
    60841 ttcctgcaag caggagcact aagaaagaga acagataggc ataacggaat aaaaacatat
    60901 tcggtgcatg cataccatgc cagaacaaat tcaatggaac aagataaaaa cttgcgataa
    60961 gtatggcgaa aagactgccg tacaaaaatt tatttttcaa cggtactttc cgactggcaa
    61021 aataaaacag acagaggact aatggtagca gacctgcgta aacgaacgga atcgatccgt
    61081 attttgtcgt gtcataaaca ccaatcatat ttttcatgat tagatccaga taagaagtcg
    61141 cttctgtttt caacgtagtg atctgactca gtgcctcgcc atttgaccga agatccagca
    61201 ctgctggcaa tacaatgatc attgaagcgc cgcctgccag taaagaagtg ataccataag
    61261 gaacaatcgt ttttttatat tctgaccagt ttgtcaatag acgggcgata aaatataaga
    61321 aagaaaatac gccaatcata aaacccatat aaaaactgga taaaaacaag agtaaataac
    61381 tgataaataa aagtttcggc cgtttaagat ccataacacg atgaatcccc aaaatcacta
    61441 atggaagata aacaaatgca tccagccaca tgatgatctc cgaatgtgca gtgataaatg
    61501 agatcaatgc gtaactgacg ctaagtgcaa catgccccca gcgaggaatc ttgaacgtac
    61561 gtgcaagaaa ccaaaaagcc aatccggcac agccgacctt aagcaaagtc agaacataca
    61621 gtgcatctgg catcatctgg tttggaaaaa agaacaccag tggcgtgaag atcccgccta
    61681 gatagtaaga aattaaagat aaataattca atcctagaga agcattccat gtataaaaaa
    61741 tactttgctt tccaagaaga acatttcgga agctggcatg aaaattagaa aactgtgaaa
    61801 aggcatcact tgccaaaata cttctgctgc ttccaggata gattccgata cttagataaa
    61861 caagtgctaa aatcaaaaac ggaatcagga aactagctgc tgcgtagcgt ccgttttctc
    61921 taaagaatga ctttaaattt tttttcatat ttattttcca ccaaatttct atgaagttgt
    61981 attcagttta tcatatcctt gtttttctct gcttaaaaag agtctagttt tcacaaaaaa
    62041 ataaaattta gaataaataa cttcataatt tgttcgtata acaaaaataa acgcaaaaaa
    62101 agggtaggaa tcaaaagtcc cacccttaaa aatttttatt aaataaaaaa ccgttcacta
    62161 tctgaacggt ccaagtatca ttcaattaaa cgcgttcaac ttttcctgat ttcaaagcac
    62221 gagttgacac ccaaactttt ttaggttttc cgtcgaccat aacgcgaact ttttgtaagt
    62281 taggtttaac agtacgtttt gttgagttca tagcgtgtga acggttgttt ccactttttg
    62341 tcttgcgacc tgtaaagtaa caaacttttg ccatggtaat ttcctccttt gccttgattt
    62401 ggagcaatag aataattcag ctcataccag actaacatat catatagaat gggaatttgc
    62461 aagtacattt tcatagatac aattgacaat tgagaagaat aattgtaaat taaacaaggt
    62521 tatacctgaa attttgcaag gtttttgagt actttgggta actgcctttt atttcaagtt
    62581 gcgctatgat aaaatatgat agaagaaaaa tgggagtttt ttacccgtta aggaggctca
    62641 ttcatggctg taaaaattca aacgtcagct ggaaccattg aaattaccaa tgatgtaatt
    62701 gcaacagttg ttggtggcgc cgcgacagat gtgttcggtg ttgtaggaat ggccagcaaa
    62761 aatcaaatta aagataatat tactgagatt ttgcgtaaag aaaattactc aagaggagta
    62821 gttgtccgcc aagaagataa tggtattgct gtagatgttt atacgattat cagctatggt
    62881 acgaaaatct ctgaagtttc ccgcaacgtc caagaaaaag tgaaatacaa tctagaggca
    62941 ttattaggcg taactgccaa ttcagttaat gtctttgtac aaggtgttcg tgtactgcca
    63001 gactaggcag gagactggct ggtaactcag cagtcgatct gaaggaggat tatctaggtg
    63061 agtgtaacag aaataagtgc aagccagttc caggaaatgg tccaggcagg tgcgaatcgt
    63121 ctgcaagtaa atgcagaata cgtcaattca ttaaatgtat tccctgtgcc agatggcgat
    63181 acgggaacaa atatgaatct atctatgact agtggagcta aggcagtagt agattcaacc
    63241 tcagaaaaag taggagaatt agcagcaatg ctttcaaaag gattgctgat gggtgcgcgc
    63301 ggaaattccg gcgttatttt gtctcaattg tttcgtggat tttctaagca aattccagat
    63361 gttgtctcat taaatgcttc tgatcttgct gcagccttca ctcatggagt tgaaactgcg
    63421 tataaagcag taatgaaacc agtagaagga acgattttga cagtagctag agaagcagcg
    63481 aaagctggag aaaagaaagc aaaaagtact gatgatgtcg ttgaagtaat gacagctgtt
    63541 gtaaaaggag caaagcgtgc tttagctaaa actccagact tgcttccagt cctaaaagaa
    63601 gtcggtgtcg tagacagtgg agggcaagga ctgctgtttg tttatgaggg ctttttaagt
    63661 gcattgaatg gagaattcca agcggatgaa acatatgaac cttctccagc agaaatggat
    63721 gatatggtca atgcagaaca tcatcgcagt gtccaaggtc aaatggcgac agaagatatc
    63781 cattttggtt actgtacaga aatcatggta aaaatcggag aaggacctac agtcgatagt
    63841 acattcgatt acgaagaatt ccgtaactat ttagatggta taggagattc tttacttgtg
    63901 gtcaatgatg acgagatcat caaagtccac gtgcatacag aaaacccagg agaagtcttg
    63961 aattatggac aaaaattcgg ttcattagtc aaaatcaaag tcgacaacat gcgcttgcag
    64021 catgagacga ttttggaaca cgatgaagaa gtgaacgagt ttgcgaaaaa agaaatacca
    64081 cgtatcccgt atggtatcgt agcgatcgct gctggtaaag gcgtccaaga gctgtttgaa
    64141 agtttaggcg ctaattatgt tatcagtggt ggacaaacaa tgaatccaag tacggaagac
    64201 attgttaaag cgattcaaga agtaaacgca gataaagtga ttgtcttgcc aaacaataag
    64261 aacatcttca tggcagctga tcaagcagca gaagtagcag atatcccagt agcagttgtt
    64321 ccttcaagaa cgatttccca aggattgaca gctatgcttt cattcaatga tcaagcttct
    64381 ttagaagaaa acaaagaaac gatgacagaa atgttgtcta gcgttgtgag cggtcaagtc
    64441 actcacgcga tcagagatac ctcaattgac ggtgtagaga tcaaagaagg agactttttg
    64501 ggcatgatcg atggaaaaat cctgatctct aacccagata tcacagcaac agcgttaagt
    64561 acactagaac aaatgatcaa tgaggacaca gagatcgtaa cgatcttggc aggtgatgaa
    64621 ggaacagttg aacaagcaaa tgaatttgct gagaaactaa cagaaaaaca tcctgatttg
    64681 gaaatcgaga tccaccaagg agatcagcct gtctatcctt atctattttc tgctgaataa
    64741 tttctgtgtc agaatatctt tctaacacag tattcattca taaaaggcct tcggttagtg
    64801 atcaggtatg atcgctgacc aagtcctttt tttgttaaag gagggaggaa aaatttatgc
    64861 gttctttaga tgatccaatc actatgctgg caggagtcgg agaaaaaaga gcagctagtc
    64921 ttgccagctt gggcatccaa acgattgaag acttactgac ttattatcct tttcgctacg
    64981 aagatattca ggaaagaaat ctaaacgaga tccaggatca agaaaaggtt actttgaaag
    65041 gaatcgtagt ctcgcctcct gtgatgaatc gatttggtta taaaaaaagc cgattgcaat
    65101 ttcgtatgat gcaagaacat gatgtgttca acgtttcttt ttttaatcaa ccttatctaa
    65161 aagaaaaagt cattttatcg gaggaaatcg ccgtatacgg taaatgggat gcaaagcgta
    65221 aagccttgaa cgggatgaag attttaggtt ctcaaacaat ggatgacttt tcgccgatat
    65281 atcacgtcaa caaatcaatt cgtcaaacga cattagttga tctaatcaaa aaagggtttc
    65341 aagaatacgg cacattgatt gaagaaaatc tgccaaacaa ccttgtggag aaatatcgac
    65401 tgcttgaccg agcttctgct gtaagaagta tgcattttcc aaaagaccac gaagaaaacc
    65461 atcaagccaa acgacgtgtc gtttttgaag agttcttttt atttcaaatg cgtcttcaag
    65521 gattgaaaaa agcagaaaaa gcagaaacga atggtttgga gatcctttat gatgtccaaa
    65581 aattgaaaca atttactcaa aagctacctt ttgaactgac aaatgcacaa aaacgtgtaa
    65641 cgaatgaaat ctgtcgggat cttcgcagtc cgcagcatat gcagcgactt ttgcagggag
    65701 atgtaggtag cggaaaaaca gtggttgccg cgattgcgtt atacgctacc gttacagcag
    65761 gtttccaagg tgcgttgatg gtgcctacag aaatcttggc acaacaacat atggaaagct
    65821 tgcaacagct gtttgatccc aatgaagtaa ccatcgcatt gattacgggg tcaacgaaag
    65881 caaaagaacg acgtgagctc cttgaaaaac tagagcaagg ggaaattaac gtcgtgatcg
    65941 gcacacatgc attgatccaa gatggagtcg aatttcagaa tttaggtcta gttattacgg
    66001 atgagcagca ccgttttggc gtgaaccagc ggaaagtact tcgtgaaaaa ggctggcgac
    66061 cagatgtctt atttatgaca gcgactccga ttcctagaac attagctatt acagcatatg
    66121 gtgagatgga tgtatctatc attgatgaac ttccagctgg acgtatcccg atcgaaacac
    66181 gctgggtaag aacacctcaa ttggacagtg tactggattg gacgaaaaaa gaactggcaa
    66241 gaggacatca aatgtatgtc atctgtccgc tgattgaaga atcagaagca ttagatgtaa
    66301 aaaatgcagt ggaaatctat gaaaaacttc gtgaactatt tgcaccaaaa tatgaagttg
    66361 gcttgttaca tggtaaaatg aagaatcagg aaaaagaagt aatcatggaa gccttcaaag
    66421 acaaccagat gcagatatta gtttcgacta ctgtaattga agtaggggta aacgtgccga
    66481 acgcgaccgt catgctgatc atggatgcgg atcgatttgg attggcacag ctgcaccaac
    66541 ttcgtggacg tgttggacgc ggaagtgatg cttcctactg tatcttagtt gctaatccta
    66601 aaaatgaact aggtgtggaa cggatgaaaa tcatgacaga gaccaccaat ggttttgtac
    66661 taagcgaaaa agatctggaa ttacgtggtc ctggtgaagt atttggcttc cgtcaatctg
    66721 gtctgcctca atttgcgatt gctgacttgg tgacggatgg aaatgttttg gaggtagcca
    66781 gagaagaggc tgcagccctt tggcaaataa aggattggca gatgcttcct gagtatcagc
    66841 ctttagcgca aagcctccaa atagaaaatc aggataatcg ttatttcgat tagcagactg
    66901 tgctatactt tatactgatg acggaaaaag gagtggaaac aatgaaaatt gccgtagatg
    66961 caatgggcgg agatcacgca cctcaagcaa ttgtagaagg cgtggcttta gcgcagcaag
    67021 attttccaga agtagaattc ttactttacg gaaaagaagc agaaatcaag aaatacttaa
    67081 caaatgaaaa aaacatcacg attatccata cagacgaaaa aatcaatagt gatgatgagc
    67141 cagtaaaagc aattcgacga aaaaagactg catcaatggt ccttgctgca caagcagtga
    67201 aaaacggtga agcagatgct gtattttcag cagggaatac aggcgcgcta ctagcagcag
    67261 ggttgttcat cgtaggacgt atcaaaaata tcgaacgccc tggcttgatg tctaccttgc
    67321 cagtagtagg gaaagaaggt gccggtttcg atatgctgga tcttggcgct aacgcagaaa
    67381 acaaaccaga acatttgttg caatacggta ttttaggttc tttttatgca cgtaaagtcc
    67441 gaggtatcgg acgtcctcgt gtcgcactct taaacaacgg aacagaagca acaaaaggta
    67501 gtgaagtgac gaaaaaagcc tatgaactcc ttcagaatga aacaagcttg aattttattg
    67561 gaaacgtaga agctcgtgag ctactcaatg gtgtggctga tgtagtggtc acagatggat
    67621 ttacaggcaa cgctgttttg aaatctattg aaggaacagc aatgaatatg atgaatctat
    67681 taaaatctgc tattctaaat gaagggatca aaggaaaaat gggcgctatg cttttaaaag
    67741 acggcttacg ttctttgaaa gcagaaatgg attattccaa acatggcggt gccgttttgt
    67801 ttggcttgaa agcaccagtc attaaaactc atggagcaac aggccccgat gctgttcgct
    67861 atacgatccg ccaaatccac acaatgcttg agacagatgt agttggacaa ttagtcgaac
    67921 aatttgaaaa aagcgaagaa tagtatttgg atatctgaag cgatccgttc cattgaaaaa
    67981 aaggtggaca ttcctgaaaa atgccagtaa aattagccat ggtgtaggta attgacaagt
    68041 gtatgattct tggaggtgaa aaagttgact cgcgaagaag tatttaacaa agtagcgaaa
    68101 attatttcaa atcattttga gatagatacc gataaagtga cggatgaatt gaacatcaaa
    68161 gatgatttaa aagctgattc aattagtatt atggaattcg ttttagagct tgaagatgaa
    68221 ttcggtacgg aaatttcaga tgaagacgct gaacaaattg aaacagtcgg tggcgcagta
    68281 gattatatca gcagccatct taaataattt caaataaaag caaagaagga taaaaagctg
    68341 catgcagctt tttatccttc tttttttaat ctttttgaca cgtaaaagtc atttttctga
    68401 taattctggc gataaacaga aattatgttg caaagtaaag cggttttcta tataattatt
    68461 aataattcat tacacaaaga taagaataac ctttgttata aaacgattta ttctgtgtaa
    68521 tgtccttttt tattaagaaa aacttccatt taggaagcag agaggggtat tcgattgtcc
    68581 gataaccaat tattagaagt tcagaaccta catacaggat tccgactcaa agatgactat
    68641 tacgatgcag tagatgacgt ttcatttact ttagacaaaa acgagatttt agcaatcgtt
    68701 ggggaatctg ggtgcgggaa aagtaccttg gctactacga ttatgggatt acttgatcct
    68761 aataacacaa aaattacagg tgagatttta tataacgatc tgaatttaat cgacctgaac
    68821 gaaacgctct ataataaaat ccgcggaaat gatatcggaa tgattttcca agatccgttg
    68881 tctgcattaa atcctctcat gagaatcgaa gaccagatca aagaaggact ttcctatcac
    68941 acaaagatga atgcagaaca gcgtcaagct cgtgcactag aattgctaga acaagtaggg
    69001 attcctaatc ctgcgagagt tggacgccaa tatccccatg aactatcagg cggtatgaga
    69061 caacgtgtca tcatcgcaat cgcaatcgcc tgcaaacctc caatcgtcat tgcagatgaa
    69121 ccgacgacag ccctagatgt aaccatccaa gcacagattc ttgatttact gaaagacctt
    69181 caggaagaaa caaaaacagg gatcatcttg atcactcatg acttaggagt cgtagcagaa
    69241 atggctgatc gagtggcagt gatgtatggc ggacagttcg ttgaagtagc aggtgtaaaa
    69301 gaactgtttg atcatcctaa gcatccttat acacgctctt tactgaactc tataccacaa
    69361 gaaggaaatc atgatgcaga actccatgtg atcgaaggtg tcgttccttc tctgaaaaac
    69421 atgcctcgta aaggttgtcg gtttgcacca cgtattccat ggataccagc aagcgatcat
    69481 gaagaagagc ctatccttca tgaagtcgca ccgaaccact tggtacgttg ctcctgctat
    69541 aagcatttcc actttagaga cgaaaaagga gaggtgtaga tgacagaatt aatcacaatc
    69601 aaagacctga aagttcatta ccctattcgc agtggattct tcaatcgagt aacggatcat
    69661 gtatatgctg tagatggtgt ggattttatt atcgaaaaag gaaagacata tggtttagtg
    69721 ggagagtctg gctctggaaa atctactacg ggaaaagccg ttgtgggatt agaaaaggta
    69781 acagccggac aaatcatgta tgaaggaaaa gatgtaacga agcgaagcaa ccgcaaaaaa
    69841 atgggttata acaaggatgt gcagatgatc ttccaagatt caatgtccag tttgaatcct
    69901 aaaaagcgag tgttggatat cattgctgaa cccatccgaa attttgaacg gttaagcgat
    69961 caagaagaaa agaaaaaggt aaaaggactg ctagatatcg ttgggatgcc ggaagatgcg
    70021 ctatataaat atcctcatga attttcaggc ggacaacgtc aacgtctagg agtagcccgt
    70081 gctgttgcta ccaatccaaa actgatcgta gccgatgaac ctgtatctgc tctggatcta
    70141 tctgttcaag cgcaagtatt gaatttcatg aaacgaatcc agcaagaata cggcctcagc
    70201 tatttattca tttcacatga tttaggtgta gtaaaacaca tgtgcgacaa tatcgcaatt
    70261 atgtacaaag gtcgatttgt agaaatcggt acaagagaag acatttataa tgacccgcga
    70321 catatctata cgaaacgtct gctttcagct attccgcaaa tcgatgtaga aaatagggaa
    70381 agccacaaag aaaatcgacg aagagtagaa caagagtata tccaaaacca aaaagaatac
    70441 tatgatgcga ctggtcgagt ctacgatttg cgtacgatca caactacaca caaagtggcg
    70501 ttgaaagatg gaggtgcaag ctaatgtgga aaacgattct gcgacgtgtt ttattgatga
    70561 tcccgcaagt tattatttta agtgttctga tcttcttatt agcccaagcg atgccggggg
    70621 atccatttac cggtttgatc aatccaaatc aggatccggc agtgatcgaa cagatgcgac
    70681 aagcagctgg cttgaatgac ccatggtatg tccagtactt ccgttggatc ggaaatgctt
    70741 tgcaaggcga ttttggtcaa agtttcttat acaaacgctc tgttgctgac ttgatcggcg
    70801 aacggatcat caacacttta tatctatcga tcttgacagt tgtccttact tatttgattg
    70861 ctgtgcctct ggggatgctt gctggccggt atcaaaattc aatcttggat aagattgtcg
    70921 taatctacaa cttctttagt tttgctgttc ctttatttat cttcggcttg atcatgctat
    70981 ttgtttttgg ttatcgttta ggctggttcc caacaagtgg atcacaaaca ctaggtttgc
    71041 aaggtggatt tatcactcaa tggatagacc gtttgaaata tattctgtta ccatcaatta
    71101 cccaagcatt tttggcgact gccgtcacaa tccaatatct gcgaagtgaa gtaatcgatt
    71161 cgaaatcgct cgattttgtc agaacagccc gttccaaagg ggtaccgacg aataaagtat
    71221 tcagtcgaca tattttccga aatgcagcgt tgccgatggc ttctcaaatg gggtatgaaa
    71281 tcacttcgtt gattgctggt tctgtagtta tcgaaaagat ttttggttat ccgggagtcg
    71341 gaaaactatt tattgattcc atcggccaac gggactatac cgtgatcaca tccttagtat
    71401 tgattttagg aatcgcgacg ctagtgggga cattactttc agatatcatc atgagtatcg
    71461 ttgacccgcg tattcggatt caataaaacc aatcagaaag gagaatggat cgatgagtga
    71521 aaaaaacaat acagcagttc aagaaagtat tcctcctatg gggatacgaa tgattgctcg
    71581 agaatttaaa aaagataaaa ttgctatttt ttcattaggt ttgctagtgg ttttattatt
    71641 agtgatcttt atcggtgcga tgctgaccga tcaagacaaa gtgatgtatg ttagtatctt
    71701 cgacaaatac gctgcaccag gaacagtttc gacacaagga caaaagttca ttctgggagc
    71761 agatgaaggc ggacgtgatg tattaggaca attgatcata ggtgctagaa actctgttac
    71821 gatcggattt gcgatcacga tccttacttc gatcatcggg gttggattag ggatcatctc
    71881 tggctactac ggagggatca ttgacaacat cttgatgcgg atcgttgatt ttatcatgat
    71941 tctaccgatc atgctgatca ttatcgtctt cgtatcgatt atttccagat acaatgtctg
    72001 gtcctttata ttcatcatga gtgcatttta ttgggtagct aaagcccgat tattccgaag
    72061 caagacatta tctgaagcaa gaagagatta tgtcagtgcc tcaaaaacaa tgggaaccaa
    72121 tgattttaaa atcatgttcc gcgaaatcat gccgaatcta agttcattaa tcattactaa
    72181 tttgacgatg aactttgcgg caaacatcgg tatcgagaca actttgactt tcttaggttt
    72241 cggcttgccg gcaaatgtac ctagtttagg tacattgatc ggttatgcaa gtaacggaga
    72301 agtcttagtg aatcggcaat ggatctggtt acccgcatca atccttattt tagttttgat
    72361 gttgagtatc aattatgttg gacaagcatt caagcgttct gcagatgcgc gccaacggtt
    72421 aggctagtat agaagcgaag ggggaaatag gaatgaagaa aacgattttt ggatttgcag
    72481 cgctgatgtc tgctgtcgtt cttgcagcat gcgggggcgg aggtacagat acctctggaa
    72541 acaactctgg aggcaacggc aataacaaag aggaattaac ttttccaatt gcaacaaaaa
    72601 ataatgatga tgcaatcgaa gacggcgaat tagaagctgc ggtcgcaacg gacagtcagt
    72661 ttaaaggatt gttccagtgg gagttttacc aagattcata tgatgcagct tttatggctc
    72721 cttctcatga accgctattt gcaaacgatg acgatttcag aatcacagac gacggagctg
    72781 caacgcttga tctagatgaa gatacgaaaa aagcgacaat caaagtaaaa gacaacgtca
    72841 aatggtcaga tggtgaagat gtaacggcgg acgatgtgat tttcccttac gaaatcattg
    72901 ggaataaaga ttacactggt atccgttatg acgacacttt ccgtaacatc gtaggtatgg
    72961 aagaatatca tgatggaagt gccgacacaa tctccggaat caaaaaaata gacgacaaaa
    73021 cagttgaaat cgaatataaa gaagtaaacc caagcatgct tcaatcgggt ggtggtatct
    73081 ggtcatatgc agcaccaaaa catacgttag aaggtgtagc aatcaaagat atggaatcaa
    73141 gcgatcaagt acgtaaaaat ccagtgactt ttggccctta ttacatgagt aatatcgttg
    73201 caggagaatc agtagaatac ttgccaaacg agcactactg gaatggtacg cctaaattga
    73261 aaaagatcac gatgaaatct gtaccgatgg caagtgcaac tgaagcattg aactctaaat
    73321 tatatgatat gattttccaa atgccaacag atacttacga tacctataaa gaaattgctg
    73381 gctatacaaa cttaggccgt gaacaaactt cttatactta tctaggattc aagttaggta
    73441 aatggaatgc agatacaaag agtgtggaat acaatccaga ttcaaaaatg gctgataaat
    73501 cattacgtca agcaatgggc tatgcattag ataataatgc agtaggtgaa cgtttctatg
    73561 caggtttgag aagcaatgcg acttcattga ttcctccagt attccagtca taccatgatg
    73621 atgagatgaa aggattcaca caagatctag acaaagcgaa aaaactatta gatgatgctg
    73681 gctacaaaga tgtggatgac gatggtttaa gagaagacaa agatggaaat aaactaacaa
    73741 tcaactttgc ttcgatgtcc ggtggggaaa cagcgcaacc attggcagat tactatatcc
    73801 aacaatggaa agaaattggt ttggatgtcc aatacacaac aggtcgtctg atcgaattca
    73861 attctttcta tgataaatta gaaaacgatg atcctgaaat tgatgtttac caagctgctt
    73921 ggaatacagg aactgatcca aatccaagtg gactatgggg accaaatgct gcgttcaact
    73981 acactcgtta tgaatcagaa gaaaatacaa aattgatcaa cgatatcagt tcaagcaaag
    74041 catttgatga agagtaccaa aaagaagcat atcaaaaatg gcaacaatat gcatttgaag
    74101 aagcatttgc gattccaacg ttgttccgta atgaagtatt gccagtcaac gaccgtgtca
    74161 aagactggga ttggtcttat gatgtaccaa acccatgggc aaatgtttct gttacagcag
    74221 attcacgttc ataatcacta aaaatgaccg aaaaagggcg atgtcctttt tcggtttttt
    74281 gatatttttc tgtttatttc tctaatattc aggtcaaggc gctgatttca tgacttctcc
    74341 aataaacggt gttcaaagtc cagtttctcg gtattaagtc aaatttatgc aaaaatatgg
    74401 aaagccattt tcacaaaatt ttttcttcat actcgaaact aaacgaattt ttcacaactt
    74461 ctcgtcaatc actaggatta ttaaagcttt acttaccttt tgaccgaacc atttcaaatt
    74521 tgacaaaaaa ccagtataat aaggaagtat cgaaaaaata tccataaaag gaatgtggaa
    74581 aatggacaac cagctgacaa aagaactaaa agaaaactat aacatcgttt ttcacgatct
    74641 aaatttgctt gaacaagctt ttacccattc atcctatgtg aatgagcatc gcaatctgca
    74701 attatcggat aatgagcgac ttgaattttt aggagatgcc gttttagaac tgatggtttc
    74761 tcagtattta ttccgtttat atcctcattt gccagaagga aaattgacaa aaacacgagc
    74821 tgcgatcgtt cgcgaagaca gcttgtcgaa atttgccaaa gaatgtcact ttgatcaata
    74881 tgttttgttg ggcaagggag aagagaattc aggaggacgt acgcgaccag cattgctttg
    74941 cgacctattc gaagcttttt taggcgcgtt atatcttgac cagggattcg acacgaccca
    75001 tgcattcatc gaaaaagtga tttttcctaa agtcaaagca ggtgcttttt cacatgagat
    75061 ggatcataaa acaaaactac aagaagtctt gcaaaaatca ggtgatgtat caatcgaata
    75121 ccgattgatc aatgaagaag gtccagctca tgaacgagta ttttggatcg aagtttatgt
    75181 agatgatcaa ttgattggca ctggacaagg gaaatcgaaa aaattagcag aacaagctgc
    75241 ggcggaaaat gcattggcag cactgtaaaa gtaagtgagg gaaagctttg tatttgaaac
    75301 gaattgaaat agccggtttt aaatcatttg cagacaagac agtcattgat tttgaaaata
    75361 gcgtcacagc agtggttgga ccaaatggca gcggaaaaag caatattaca gaggctatcc
    75421 gctgggtatt aggagaacaa tctgctaaaa gtctgcgagg cggaaaaatg ccggatatca
    75481 tctttgccgg ttccgatacc cgtaagcagc tgaatattgc agaagtcaca gtgattttag
    75541 acaatagtga tcattatctg ccattggagt acaatgagat cagtgtaacc cgccgttatc
    75601 gacggactgg ggaaagcgag tttttcatca ataaacaaag ctgcagatta aaagatatcc
    75661 aagaattgtt cttagattct ggattaggaa aagaatcgtt ctcaatcatt tctcaaggaa
    75721 aagtagaagc gattttcagt agtaaaccgg aagaccgtcg tgggatcttt gaagaagcag
    75781 ctggtgtctt gaaatacaag cagcggaaaa agaaagcaga acagaagctt tttgaaacag
    75841 aagacaacct cagccgcgtc caagacatca tccacgaatt ggaagaacag ttaactcctt
    75901 tggccgccca gagtgaggca gcaaaggagt ttttacggct aaaagaaaca ctgactcaaa
    75961 ccgatgtctc tttgatggtt gctgaaatca agacagcaaa aaaagattgg gacaacaaac
    76021 aagcacagct tgcgaaattc aatctagaat taggcaaact atctgagtcg atccaagaac
    76081 aagaatccat tttggcgaag cagcgtaaag aaaatgcgca agccgatcgt ctgatcgaaa
    76141 aaaatcagca agtattatta gatctttcgg aaaaactgaa gcagacagaa ggacaaaaag
    76201 atgttttgca ggagcggaca aagcatacac aaaaaagctc gcaagaatat caaacttcat
    76261 tagcagaagc acaaaaaaag gttaaacatt ttgaaaagct tcaagaaagc ttgatgaaag
    76321 cagcagcaga aaaagaaaca gagatccaaa aagctgaagc aaatctcata aaaacacagc
    76381 aagaattaga aaaataccaa aaatcaacga aagaattatt ggcagaatta agagatcaat
    76441 atgttgattt gatgcaagaa caagcagctg taggaaacga actgaagtat ctagaacgtc
    76501 aatatataca agaaacagca aaaagcaagc agacgttagc caagcaatcg gaagtagaag
    76561 catcagtaga ccgattgatc ttacaaaaag aagaattgac acaaaagcag gcgcagctaa
    76621 aatcatcttt aactgaaaca aaagagaagt tagaaatgat ccaacaaaac gggaaaaagt
    76681 tccaagaagc attagcaaaa gaacagccta aaatgtatca attaatgaat caagtccagc
    76741 agctacgtgc tcgtaagaaa agccttcaag aaatccaaga aaactatttt ggtttttacc
    76801 aaggggttcg attggtcttg cagcataaac agcagctttc gggtattgtc ggagcagtgg
    76861 ctgaactgat cgatgttcct gcagatttca cgttagctat cgaaacagct ttaggtgggg
    76921 cagcccagca tgtcatcgtt gaaaatgaaa aagatgctcg gcaagccatc acgtatttga
    76981 aacagcaaag aggaggaaga gcaacattcc ttccactgac gacaatcaaa ccaagacaat
    77041 taccggctca tatattgaca caagcagcag ctgtagaagg gtttataggg attgccagtg
    77101 aacaagtcag ttatcccgat caaatccaaa ctgtggttca aaacctgcta ggaacgatcc
    77161 ttttagccaa agacttaact agtgccaatg caatcgcgca aacgatccgc tatcaatatc
    77221 gagtggtttc cttagaaggt gatgtgatga atgccggagg atccatgaca ggtggagcga
    77281 ataaacgagg aaaccaaggc agtttgtttg tacaaaatca agaattgaaa cagttgacta
    77341 gtgaatttga agaagcagat aaacaactcc aagcacaaga aaaaaaagtt caggagctgc
    77401 aacaagaaac agctcgttta gccgaagaac aagaagtttt gcgtacacga ggcgaacaat
    77461 tacgttttga agaacaagaa gcgacaaatc agctacaaaa catcataaat gaacttgaac
    77521 gttttgaaaa agaaaagcaa atctcaactt ttgagacacg tgaactgcag cagtttatcg
    77581 aagattacga aaagcaaacg aacgaattga aagacaaaca aacagatctt gaatcgcaac
    77641 gacaaaaaat cgacgaagaa atcaaatcgt taagtcaaga aagcgaccag atggaagcca
    77701 gaagagcaca agtacaaagt caaaaagcac aagaacaagc agatcttgct gtcttgaaag
    77761 agcagtttaa tcatctgcag atccagctcc gcggtgcccg agtccaaaaa gcagaggcaa
    77821 ccgaacgtca agaagcgata gaaaagcagt tggcgacatt gacagcagac ttttctgatc
    77881 atgaagtcac agaagaaagt ttggaaaaac aaattaacga attatctgct cagcgagaaa
    77941 cattaaaagc cgagttggca aaagccaaag agcagcgaga tagaaggcaa aaggagatcg
    78001 ataagcttga agcagtcttg gcagagcgta atcgtgagca aaaagcacga ctgtcggaac
    78061 aatccaaatt agaagtccaa aaagaccgag ctgaaatgat tttagataat catttgacct
    78121 atctgcagtc agaatatcag ctgacatttg agaaagcttc ccaagactat caagaaacaa
    78181 ccgatatcga agacagtaga acaaaggttt catccttaaa agaacagatt gaaaaactgg
    78241 gaccagtaaa cttaaattca atcgaacaat acgaacaagt cagtgaaaga catacattct
    78301 tagcaacaca gcgagatgat ctgttagcag cgaaaaacca attgtttgaa acgatggatg
    78361 agatggatga tgaagtgcgg acaagattca aagaagtatt tgaagctatc cgtcaagaat
    78421 tcaaaattgt ctttccaaat atgtttggcg gcggtaaagc tgaattagta ctgacggaac
    78481 caactgattt gctgaaaaca ggtattgaga ttgaagtaca acctcctggc aaaaaactgc
    78541 aaagtctaag tttgctttct ggaggagaac gagcacttac agccatcgcg ttgctctttt
    78601 ccattatccg tgtctgtcct gttccgtttt gtatcttaga tgaggtagaa gcagcgttag
    78661 atgaagccaa cgtgaaacgt tttggtcgtt acttgagcga tttccaagat gacacacaat
    78721 ttatcgtagt cacacaccgc aaaggaacga tggtcgcagc agatgtactg tacggagtga
    78781 cgatgcagga atccggtgta tcaaaaatcg tttctgtacg gatggaagat atcaatgaag
    78841 aggcgaaaat caacgaaacg aaagtgtagg aacgaaaatg atcaaattag tagcaatcga
    78901 tttggacggt acattattaa atgaacaaaa gctgatttca gatgagaata aacaagcatt
    78961 agcacaagca aaacagcaag gggtcaagat cgttctatgt acaggacgcc ccttagctgc
    79021 gatggcgcat tatctgcaag aattaggact ggtagatgaa ggtgactaca gcatcacttt
    79081 caacggcggt ttggtacaaa aaaatgatac tggtgaaatc atggaaaaga aagtgatgga
    79141 agtatcagat atccaacgct tatacaaact ggctcagcaa ttggatctgc cactagatgt
    79201 tttgtctgac aatgtggttt tacagctgcc tagtgcccca aggaagcaat ccttgtacaa
    79261 tgtgttgaat aagctgctgc aattccaacc agcggatata agcgatatta cagatgaatt
    79321 tgtgcttaat aaggcagtaa tcgcttatga ccaagaagaa ttagatccta aaatcaaaga
    79381 aataccagca gaattccatg aaatgtatga gatcatcaaa acaagaagta tgcttttgga
    79441 atttatgcca aaaggtgtta caaaagctta tggtatttct ttattggcaa aagatcttgg
    79501 tttgaaacaa gaagaaatca tggcgatcgg tgatgaggaa aatgatttac cgatgatcca
    79561 atatgctgga ctaggcgtag cgatggagaa tgctgtgcct ttcgtcaaag aagcagcaga
    79621 tttcgtgaca gccagcaatg aagaaaatgg cgtagccaaa gtgatccaaa aatttgtatt
    79681 agagtagggg gagtcaaatg ggattttttg ataaaatcaa gcgtgctttt actggcgaag
    79741 agaaaacaga agaagttgaa gtacaggaga agtacgacaa gggtttagaa aagacgcgta
    79801 aaacatttgg tgaacggatg aatgagttgt ttgccaattt tcgaacagtc gatgaagact
    79861 tttttgaaga attagaagaa acacttatcg gtgcagatgt aggttttgaa acagcgatac
    79921 gaattaccga agcattacgt caagaagtga aactcagaaa tgcgaaaaaa tcggcagaag
    79981 tccaaaatgc gatcatcgag aaacttgtgg atctctatga agcggaagga atcaatgaag
    80041 taaatgaact aaatatccaa gaagacggac taacagttat tttgtttgtc ggtgttaatg
    80101 gtgtagggaa aacaacaagt attggtaaac ttgcccatca gttcaaaaac gaaggtaaaa
    80161 aagtattgat ggcagcagca gataccttcc gcgctggagc aatcgaccag ttagttgtct
    80221 ggggcgaacg cgctggtgtt gaagttgttc gtggcaatgc aggaggcgat ccagcagctg
    80281 tcgtattcga tgctttggaa agagcaaaga cagagcaggc agatgtttta ctagttgata
    80341 ctgcaggccg actgcaaaat aaagtgaact tgatgaacga attagaaaaa ataaaacgag
    80401 taatccagcg ggaattacca gaagcacccc aagaaacact tcttgtatta gatgcaacca
    80461 ctggtcaaaa cgcgatggtt caagcaaaac aattcaaaga aacaacagat gtgaccggtc
    80521 ttgttttgac aaaattagat ggtacagcaa agggcggtat cgtacttgct atccgtaatg
    80581 aattgcattt accagtgaaa ttggtcggtc ttggtgaagg aatcgatgac ttggagccgt
    80641 ttgatccaaa tgattttgtc gttggattgt tcaaaggatt actaaaagaa gaataaccca
    80701 tgtctaaaaa gcaggagctg tgacaaaagt tgcagctcct tgtttgaatg attgttttta
    80761 acatagctgt gtttttgatg ccttcatttt tatacttatt tgtaagcggt tctcaaacaa
    80821 tttcgttctt tttcttagac tttttgatta taattagatt catatgaatt ggaggtcact
    80881 taatgatgaa ttttaagcaa ttattattgc atgtcaatgc gcgccctttt atcgaccaag
    80941 ctcgatttgg tatagaacgg gaaggacagc gggttgatct tgcaggaaat ctagcaaaaa
    81001 ccgatcatcc agcaatcttt ggcgatcgat cctatcaccc ctatatccaa acagatttta
    81061 gcgaaacaca aacagagatg atcacccctg ttaccgattc tattcccgaa ttatttcagt
    81121 atctcgctgc tgtttatgat gtgactgctc gttctatacc gaaagaagag atgatctggc
    81181 cattaagtat gccacctgcc ttaccggaaa aagacgaaga gatcattatt gcaaaattaa
    81241 aaaatttcga agatgtcttg tatcgacgtt atttagcaaa agaatacggg aagcgaaaac
    81301 agatggtaag cggtattcat ttcaattttg aatttggcga tgagttgcta agaacattgt
    81361 tcagccatca ggaagaattt caagattttt ccgaattcaa aacagaactt tatttgaaaa
    81421 cagcgagaaa ctttatgcgc tatcgctgga tgatcactta tttattcggt gcttcaccaa
    81481 tgagtgagaa gaactacttt ttagatgaat cacatccgca agaacctgtt cgcagtattc
    81541 gcaacagtgc gctgggctat acgaatcatc caaatgtgaa agtttcctat gcttctatga
    81601 aacagtattt agcagatatc gagcgaatga tcgaagaagg gaaactttcg gaggagaaag
    81661 aattttatac accgcttcgt ttccgaggcg gaaagaaagt cgcagattta gcaacaacag
    81721 gtgttcgtta tattgaattg cggaatatcg atttgaatcc ttatgcaaga ttgggtatca
    81781 atccagagca agttcggttc ttacaattat tcctgatgta catgttatgg acagaagaaa
    81841 aagaagactg tgaccaatgg gtagcagaag gtacgactcg aaataacaaa gtagcactag
    81901 aacaaccatc agatcaaaca gaatttcatc aagaaggtag agaaattctt gaaggaatga
    81961 agcaaatgct ggttgaattg gattggttgg attctcttta tttagtagag gaagcattga
    82021 ctcaaatgga tcatcctgaa caaacgttag cagcgaaact ctatcaagaa gcacagctat
    82081 cgagtcagca agaagttgct gtggcattgg gacatcaata ttataaagaa agccatgaac
    82141 gtccctatca gttggccggt tttcgcgaaa tggaactttc tactcagata tttatgttcg
    82201 atgccatcca aaaaggtgtc caagtcaaag tattagatga gtcggatcaa tttttgcgtc
    82261 tgcaattcca agaccatgta gaatatgtga aaaatgcaaa catgacaagt aaggacagct
    82321 atatcgtccc acttatcatg gaaaacaaaa cagtaacgaa aaaagtctta aaagaagctg
    82381 ggttccgggt accaggaggc gcagaatttt catccatgga agaagcggta aaagcttatc
    82441 cgagatttgc cgagcaggca tttgtgatca aacctaaatc aaccaattac gggttaggta
    82501 tcacgatttt caaggaagga gctagtctgg aagattatca agcaggttta gccattgctt
    82561 ttcgtgaaga cagttcggtt ttagtagaag aatttatgcc gggaacggaa tatcgtttct
    82621 ttgtgatcga cggagaagtc caagccatca tgttgcgagt ccctgctaat gttattggtg
    82681 acagtatccg aacagtgaaa gaacttgttg aagaaaaaaa tagtgaccct ttgcgtggaa
    82741 cgaatcatcg tgcaccttta gaattgatcc aattaggtga attagaacaa ttgatgttga
    82801 aagaacaagg gttgacgatc gaatcagttc cccaagccaa tcaaattgtt tatctaaggg
    82861 agaactcaaa tatcagtaca ggtggtgatt cgatcgatat gactgatgaa ttttctgaag
    82921 cttacaaaaa aatcgccgtt tctgcggtag aagcactagg agctaagatt agtggtatcg
    82981 atttgattat accagataaa gaaatcgatc ctacaactga taaaaaagca tatgggatca
    83041 tcgaagcaaa tttcaatcca gccatgcata tgcatgttta tccttttgca ggaaaaggca
    83101 gaagattgac gatgaatgta ttgaaattgt tatatcctga agtattttaa aagaaaaagc
    83161 ttttgacaga ttgtcctatt tgatgtcaat ctgatcaaaa gctttttttg catgtaaaaa
    83221 tttatgtgtt ttttcgtttt aaaataaacg atcccagaag ctttttttct tttttggttt
    83281 ttctttttca gctggcgaag agttttcttc tgggtatttt ttttcgatat caatcacagg
    83341 ttcatttact gcttcttttg ctgttaagag caatccgaat tcctcaggat ttgcagtgac
    83401 gtaatcgttg actacagtga aacggctatt gtttttcgtt gctagctgga tatattggtt
    83461 ttggacagaa aggggtagag ccccattcaa gagtatggaa gcatctggat gttttttgag
    83521 ttcttttaaa aagttttctt tgttttttgg ttggatcatt tcagcaacag tcatactaag
    83581 atagcagcgt tccctgaatg tccctaaata tttatgctgt tcttcagggt tcactaaagg
    83641 tgtaccataa agtcccttat ccaaatggct ttttacatca tcttgtgcca taaaaaatac
    83701 cctccttctt ctctttgtct ttcttacgat tatagcatat tcccaataat acctaaaaca
    83761 tatgaaaaag cggttgcttt tgttcaacga ttcacttaaa ataagaatga aaatcattct
    83821 caattagaaa ggtggattgg atgcgctacg gacgactagt agcattatta gttattttaa
    83881 gtagtatttc attgttcatc ggagtatcga atgtacaatt gtcagaactg ctccagttag
    83941 atgggcaaag cttacaaatc ttgctagtga ctcgtttgcc acgaacgatt tgtttgatcc
    84001 ttgtgggagc gaccagtagt atttgtgggt tgatcatgca acatttgacc caaaataaat
    84061 ttgtttcacc aacgactgcg ggcacgatgg atagtgcgcg tttaggtatt ttagtggcta
    84121 tgattttcct acctggtgca tccttgattg tccgatcctt gacagcattt tgctttgctt
    84181 ttgcaggaac attgcttttt ttatccctta cgcgattgtt cctccagaaa aatcaattga
    84241 tgcttccgtt gattggagtc atgttaggga atatcattgg ttcagttgct actttttttg
    84301 cttatcaatt ccagttggta caaaatatga cttcatggct tcaagggaat tttgcgactg
    84361 tgatacgagg aaattatgag ttattgtatg ctgttgttcc attgttgctc ttggtttggc
    84421 tatttgctta ccgatttacg atcattggtc tgggcgaatc gtttgcagta aatctgggaa
    84481 tagattacca gaagatgcag tttttaggca ttggcttagt atcattggct agtgcagtca
    84541 tgttgatcat ggtaggaagc attcctttta tcggagtgat cattccgaat cttgtctcta
    84601 gaatatatgg agatcaagtg cacaaaacaa ttggcgtaac tgctttagca ggtagtttgt
    84661 tcttagtatt ttgcgatctt gtcgctcgcg tgttgatttt tccttatgaa ataccagtca
    84721 gtgtgatcgt tggaatcatc ggtggggcta tcttccttta tcttctgata aggggacgac
    84781 gatatgctta aaaaaaagcc atctattttt attggtatgc ttgttcttgt tttatttgtt
    84841 acaggaatgt acttgacgat ccatacatat ggaaactggc attttgcatg tgcattgagg
    84901 agtaagaaaa tttttgcatt tatccttgtc tcgctagctg tcagcagtgc cacaatcagc
    84961 tttcagacaa ttacgcataa ccagtttttg actccttcag tattgggact tgagtcgtta
    85021 tatgtccttg tccaaacggt ccttttcttc tttatcggag gagtgacgat gcttcagcag
    85081 acaggtacag tttttttctt attgaacgtt gggctgatgg tcgggctgag tctattgtta
    85141 tttttctttc ttttgaaaaa aatgagagcg aatctttttt tattactgat gtcagggatg
    85201 attttaggta cgctttttgg tagtgtcagt acctttttac aagtcatcat ggatccgaat
    85261 gaatatgatt tgcttcaagg cagattattt gcaagctttg gcaatatcca gagtcagtat
    85321 cttttgcctg cttctttgat cattatcggc tgctggtacc tgttatttcg atatcgacat
    85381 gtgctagacg ttttccatct cggaaatgaa caagcagtaa acctcgggat agacacagat
    85441 cgttttgaat ttttgatttt atgttgtgtc agtcttttga cagggacatc aacggctctt
    85501 gtgggtccag ttactttttt agggtttatt gtcgcaaata tcagttatcg tgtcttttct
    85561 acttatcgtc atggtcagct atttatcgga agctttctgg tagctatgct gtttctgaca
    85621 ggaggacagc tcgcagtaga gcagattttc ggctggaata caacagtgag tgtcgtcgtt
    85681 gaatttgtcg gaggaattta ttttgtcaca aaattgattc gcgaaaggaa gagtatccta
    85741 tgattgattt acaaaaggtc aataaactgt accatggaaa atcagtggtt aaagatgtac
    85801 agttaacgat tcctgaaaag aaattgactg cttttatcgg tccaaatggt gctggaaagt
    85861 caacggtgtt gtcgatgatc agtcgtttga taccaaaaga tacaggtgaa atctatttag
    85921 accataacga agtaaaggct tggaaatcca atgaattagc caaaaaatta tcgatcctac
    85981 gacaatcgaa tgaaataaat gtccaaatca ccgtgaaaga attagtagaa tttggacgat
    86041 ttccttatac gaaaggaaaa ttgacgacaa aagacgagga aatcgttcag gaatcactgg
    86101 aacaccttgg gttagaagaa atagcggatc aatcgattga cactctttca ggcggtcaac
    86161 tccaacgtgc gtatattgca atggtgctag cgcaagacac ggattatatt ttactggatg
    86221 aacctttgaa caatctagat atgaattttg cggttcaaat catgcagatt ttaaaaaatt
    86281 tagtacaaga aatcgggaaa acaattgtta ttgttcttca tgatatcaac tttgctgcaa
    86341 gttatgcaga cgaaattgtt gcaatgaaag atggacagtt atttacgcaa ggaacgaccc
    86401 aagaaatgat aaaaaaagat gtattggatg aattatacga aatggacata cggatttgtg
    86461 agattgaagg ccgcagattc tgtctttatt tctaaaacta acattaggag agaagagatg
    86521 aaaaaattag tagtaggtat cttgattcta gcatcatttg gtttagcagc atgtggaaat
    86581 agcaacaaca ccagtcaggc agacacaaaa aaaagcagca cacaaactga aactacattg
    86641 acgataacag atagtaatgg agaccaaatc gaggtgccaa ataatccaga aaaagtcgtc
    86701 gtattcgaca atggttcttt agatacgatg gatgctcttg gtgttggaga taaggtagtt
    86761 ggagcagcta caagcagcct tcctgagtat ctttcatcct ataaaaaagt agaatcagca
    86821 ggtggaataa aagaaccaga cttagaaaaa attaatcagc ttcagccaga tctaatcatc
    86881 atttctggcc gacaaagaga ttttcaaaaa gatctaagtc aaattgctcc gaccattttc
    86941 ctttctttag atgcgaaaaa tccatgggaa tctttccagc aaaatgtcac tgctttaggg
    87001 gagatctttg gtaagcaaga agaagctaaa actcaattag aggaattatc tagtgcaatc
    87061 gatcagacga aaaagaaagc agaagctact gacaaaaaag cactagtcac acttgtgaat
    87121 gaagggcaat tatcagccta cggatctggt tctagattcg gtttcatcca tgatttattt
    87181 ggctttgaac aagcagatga tcaaatcgaa gcatccactc acggtcaaag tgtttcttat
    87241 gaatatgtgc tggaaaaaaa tccggatatc ttatttgtag tagacagaac aaaagctatt
    87301 ggtggagacg acagcaaaga tgatatttct gccaatgaac tggtagcaca aacgaatgct
    87361 ggtaaaaatc agcagatcat ctcccttgaa ccagatgtct ggtatttaag cgggggcggt
    87421 ttagaatcaa tgaaactgat gatcgaagat gtgaatcaag catttaaata gcataaataa
    87481 cagaggatta aactctcata ctatgtaaca ataatgtttc ttacattctt aaatagcaag
    87541 agcctatcct caaagaagtt atcaaaaacc atccgtaaaa tcgtattgat gattttacgg
    87601 atggttttta tttatttgag aaatcttttt tcaacgtgaa ttcattatct acatcatacg
    87661 ggttgattct agaatgggga gtggcaaaaa atagtgtgat ccattttttc agcatcaaga
    87721 tcgcctcctt tgatttgaat caaaggtaca aagcgaaact tagataaaac ttaaatttag
    87781 atatttttat tttgtaccga tctcttcttt aaacgatgtt ccatctgctg cttctcggca
    87841 ataagtccac tagactagaa aatatgagaa gctattttct gtccagcgtt cttattactc
    87901 aaagcaaatc gcagttgtca caatctcttc taaacgatgt tccatctgct gcttctcggc
    87961 aataagccca ctagactaga aaatatgaga agctattt
//
LOCUS       DACGDM010000003        86319 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.003, whole genome shotgun sequence.
ACCESSION   DACGDM010000003 DACGDM010000000
VERSION     DACGDM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 86319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.003"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            63..1187
                     /locus_tag="IXR05_000206"
     CDS             63..1187
                     /locus_tag="IXR05_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4258760.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            1414..2331
                     /locus_tag="IXR05_000207"
     CDS             1414..2331
                     /locus_tag="IXR05_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4258761.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            2324..3157
                     /locus_tag="IXR05_000208"
     CDS             2324..3157
                     /locus_tag="IXR05_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4258762.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            3240..4358
                     /locus_tag="IXR05_000209"
     CDS             3240..4358
                     /locus_tag="IXR05_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4258763.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            4352..6250
                     /locus_tag="IXR05_000210"
     CDS             4352..6250
                     /locus_tag="IXR05_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAQ4258764.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            6244..7467
                     /locus_tag="IXR05_000211"
     CDS             6244..7467
                     /locus_tag="IXR05_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAQ4258765.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(7553..9487)
                     /locus_tag="IXR05_000212"
     CDS             complement(7553..9487)
                     /locus_tag="IXR05_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4258766.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            9713..10369
                     /locus_tag="IXR05_000213"
     CDS             9713..10369
                     /locus_tag="IXR05_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4258767.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(10443..10796)
                     /locus_tag="IXR05_000214"
     CDS             complement(10443..10796)
                     /locus_tag="IXR05_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4258768.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            10988..11917
                     /locus_tag="IXR05_000215"
     CDS             10988..11917
                     /locus_tag="IXR05_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAQ4258769.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            11928..12764
                     /locus_tag="IXR05_000216"
     CDS             11928..12764
                     /locus_tag="IXR05_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAQ4258770.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            13012..13788
                     /locus_tag="IXR05_000217"
     CDS             13012..13788
                     /locus_tag="IXR05_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4258771.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            13964..14707
                     /locus_tag="IXR05_000218"
     CDS             13964..14707
                     /locus_tag="IXR05_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258772.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            14700..16280
                     /locus_tag="IXR05_000219"
     CDS             14700..16280
                     /locus_tag="IXR05_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAQ4258773.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(16531..17010)
                     /locus_tag="IXR05_000220"
     CDS             complement(16531..17010)
                     /locus_tag="IXR05_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAQ4258774.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(17026..17778)
                     /locus_tag="IXR05_000221"
     CDS             complement(17026..17778)
                     /locus_tag="IXR05_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAQ4258775.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            17895..17965
                     /locus_tag="IXR05_000222"
     tRNA            17895..17965
                     /locus_tag="IXR05_000222"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17927..17929,aa:Gly,seq:ccc)
     gene            18326..19051
                     /locus_tag="IXR05_000223"
     CDS             18326..19051
                     /locus_tag="IXR05_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAQ4258776.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            19306..19572
                     /locus_tag="IXR05_000224"
     CDS             19306..19572
                     /locus_tag="IXR05_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAQ4258777.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            19569..20000
                     /gene="ruvX"
                     /locus_tag="IXR05_000225"
     CDS             19569..20000
                     /gene="ruvX"
                     /locus_tag="IXR05_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAQ4258778.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            20025..20330
                     /locus_tag="IXR05_000226"
     CDS             20025..20330
                     /locus_tag="IXR05_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAQ4258779.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(20411..21556)
                     /locus_tag="IXR05_000227"
     CDS             complement(20411..21556)
                     /locus_tag="IXR05_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4258780.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(21617..22264)
                     /locus_tag="IXR05_000228"
     CDS             complement(21617..22264)
                     /locus_tag="IXR05_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4258781.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            22458..22751
                     /locus_tag="IXR05_000229"
     CDS             22458..22751
                     /locus_tag="IXR05_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258782.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            22795..23106
                     /locus_tag="IXR05_000230"
     CDS             22795..23106
                     /locus_tag="IXR05_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258783.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            23103..23727
                     /locus_tag="IXR05_000231"
                     /pseudo
     CDS             23103..23727
                     /locus_tag="IXR05_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            24027..24389
                     /locus_tag="IXR05_000232"
     CDS             24027..24389
                     /locus_tag="IXR05_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258784.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            24426..25274
                     /locus_tag="IXR05_000233"
     CDS             24426..25274
                     /locus_tag="IXR05_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAQ4258785.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            25264..26739
                     /locus_tag="IXR05_000234"
     CDS             25264..26739
                     /locus_tag="IXR05_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAQ4258786.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            27005..27412
                     /locus_tag="IXR05_000235"
     CDS             27005..27412
                     /locus_tag="IXR05_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAQ4258787.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            27415..27630
                     /locus_tag="IXR05_000236"
     CDS             27415..27630
                     /locus_tag="IXR05_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258788.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            27634..28014
                     /locus_tag="IXR05_000237"
     CDS             27634..28014
                     /locus_tag="IXR05_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4258789.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            28148..28303
                     /locus_tag="IXR05_000238"
     CDS             28148..28303
                     /locus_tag="IXR05_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAQ4258790.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            28372..28845
                     /locus_tag="IXR05_000239"
     CDS             28372..28845
                     /locus_tag="IXR05_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAQ4258791.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            28842..30536
                     /locus_tag="IXR05_000240"
     CDS             28842..30536
                     /locus_tag="IXR05_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4258792.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            30502..30687
                     /locus_tag="IXR05_000241"
     CDS             30502..30687
                     /locus_tag="IXR05_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258793.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            30691..31866
                     /locus_tag="IXR05_000242"
     CDS             30691..31866
                     /locus_tag="IXR05_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4258794.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            31859..33382
                     /locus_tag="IXR05_000243"
     CDS             31859..33382
                     /locus_tag="IXR05_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4258795.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            33438..33722
                     /locus_tag="IXR05_000244"
     CDS             33438..33722
                     /locus_tag="IXR05_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAQ4258796.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            33709..34044
                     /locus_tag="IXR05_000245"
     CDS             33709..34044
                     /locus_tag="IXR05_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAQ4258797.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            34339..34965
                     /locus_tag="IXR05_000246"
     CDS             34339..34965
                     /locus_tag="IXR05_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258798.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            35707..36544
                     /locus_tag="IXR05_000247"
                     /pseudo
     CDS             35707..36544
                     /locus_tag="IXR05_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
     gene            36609..37043
                     /locus_tag="IXR05_000248"
     CDS             36609..37043
                     /locus_tag="IXR05_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4258799.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(37111..38433)
                     /locus_tag="IXR05_000249"
     CDS             complement(37111..38433)
                     /locus_tag="IXR05_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAQ4258800.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(38587..40227)
                     /locus_tag="IXR05_000250"
     CDS             complement(38587..40227)
                     /locus_tag="IXR05_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAQ4258801.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            40557..41027
                     /locus_tag="IXR05_000251"
     CDS             40557..41027
                     /locus_tag="IXR05_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAQ4258802.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            41656..42759
                     /locus_tag="IXR05_000252"
     CDS             41656..42759
                     /locus_tag="IXR05_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4258803.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            43043..43723
                     /locus_tag="IXR05_000253"
     CDS             43043..43723
                     /locus_tag="IXR05_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4258804.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            43813..44847
                     /locus_tag="IXR05_000254"
     CDS             43813..44847
                     /locus_tag="IXR05_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4258805.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            44861..45196
                     /locus_tag="IXR05_000255"
     CDS             44861..45196
                     /locus_tag="IXR05_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258806.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            45180..47660
                     /locus_tag="IXR05_000256"
     CDS             45180..47660
                     /locus_tag="IXR05_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258807.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            47716..49275
                     /locus_tag="IXR05_000257"
     CDS             47716..49275
                     /locus_tag="IXR05_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4258808.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            49272..50636
                     /locus_tag="IXR05_000258"
     CDS             49272..50636
                     /locus_tag="IXR05_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4258809.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            50807..51877
                     /locus_tag="IXR05_000259"
     CDS             50807..51877
                     /locus_tag="IXR05_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258810.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            51892..52560
                     /locus_tag="IXR05_000260"
     CDS             51892..52560
                     /locus_tag="IXR05_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258811.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            52580..53158
                     /locus_tag="IXR05_000261"
     CDS             52580..53158
                     /locus_tag="IXR05_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4258812.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            53561..54472
                     /locus_tag="IXR05_000262"
     CDS             53561..54472
                     /locus_tag="IXR05_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4258813.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(54728..55645)
                     /locus_tag="IXR05_000263"
     CDS             complement(54728..55645)
                     /locus_tag="IXR05_000263"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAQ4258814.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            55847..56284
                     /gene="zapA"
                     /locus_tag="IXR05_000264"
     CDS             55847..56284
                     /gene="zapA"
                     /locus_tag="IXR05_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAQ4258815.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            56342..56889
                     /locus_tag="IXR05_000265"
                     /pseudo
     CDS             56342..56889
                     /locus_tag="IXR05_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
     gene            57004..59364
                     /locus_tag="IXR05_000266"
     CDS             57004..59364
                     /locus_tag="IXR05_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAQ4258816.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            59451..59765
                     /gene="trxA"
                     /locus_tag="IXR05_000267"
     CDS             59451..59765
                     /gene="trxA"
                     /locus_tag="IXR05_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAQ4258817.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            59947..61725
                     /gene="uvrC"
                     /locus_tag="IXR05_000268"
     CDS             59947..61725
                     /gene="uvrC"
                     /locus_tag="IXR05_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAQ4258818.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            61870..62769
                     /locus_tag="IXR05_000269"
     CDS             61870..62769
                     /locus_tag="IXR05_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258819.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            62762..64024
                     /locus_tag="IXR05_000270"
     CDS             62762..64024
                     /locus_tag="IXR05_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258820.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            64187..66085
                     /locus_tag="IXR05_000271"
     CDS             64187..66085
                     /locus_tag="IXR05_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAQ4258821.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(66384..67103)
                     /locus_tag="IXR05_000272"
     CDS             complement(66384..67103)
                     /locus_tag="IXR05_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAQ4258822.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            67440..67772
                     /locus_tag="IXR05_000273"
     CDS             67440..67772
                     /locus_tag="IXR05_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258823.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            67759..69762
                     /locus_tag="IXR05_000274"
     CDS             67759..69762
                     /locus_tag="IXR05_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAQ4258824.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            69781..70251
                     /locus_tag="IXR05_000275"
     CDS             69781..70251
                     /locus_tag="IXR05_000275"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAQ4258825.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            70272..70856
                     /locus_tag="IXR05_000276"
     CDS             70272..70856
                     /locus_tag="IXR05_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAQ4258826.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            70871..71857
                     /locus_tag="IXR05_000277"
     CDS             70871..71857
                     /locus_tag="IXR05_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAQ4258827.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            71847..72158
                     /locus_tag="IXR05_000278"
     CDS             71847..72158
                     /locus_tag="IXR05_000278"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAQ4258828.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            72180..73961
                     /locus_tag="IXR05_000279"
     CDS             72180..73961
                     /locus_tag="IXR05_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAQ4258829.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            73954..75330
                     /locus_tag="IXR05_000280"
     CDS             73954..75330
                     /locus_tag="IXR05_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAQ4258830.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            75337..75972
                     /locus_tag="IXR05_000281"
     CDS             75337..75972
                     /locus_tag="IXR05_000281"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAQ4258831.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            76002..77357
                     /locus_tag="IXR05_000282"
     CDS             76002..77357
                     /locus_tag="IXR05_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAQ4258832.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(77549..78943)
                     /locus_tag="IXR05_000283"
     CDS             complement(77549..78943)
                     /locus_tag="IXR05_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4258833.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            79035..80006
                     /locus_tag="IXR05_000284"
     CDS             79035..80006
                     /locus_tag="IXR05_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAQ4258834.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            80003..80785
                     /locus_tag="IXR05_000285"
     CDS             80003..80785
                     /locus_tag="IXR05_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAQ4258835.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(80954..81325)
                     /locus_tag="IXR05_000286"
     CDS             complement(80954..81325)
                     /locus_tag="IXR05_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4258836.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            81459..81902
                     /locus_tag="IXR05_000287"
     CDS             81459..81902
                     /locus_tag="IXR05_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4258837.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(81945..82754)
                     /gene="yidA"
                     /locus_tag="IXR05_000288"
     CDS             complement(81945..82754)
                     /gene="yidA"
                     /locus_tag="IXR05_000288"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAQ4258838.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(82773..84140)
                     /locus_tag="IXR05_000289"
     CDS             complement(82773..84140)
                     /locus_tag="IXR05_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4258839.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(84124..84954)
                     /locus_tag="IXR05_000290"
     CDS             complement(84124..84954)
                     /locus_tag="IXR05_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAQ4258840.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            85117..85554
                     /locus_tag="IXR05_000291"
     CDS             85117..85554
                     /locus_tag="IXR05_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAQ4258841.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            85630..86250
                     /locus_tag="IXR05_000292"
     CDS             85630..86250
                     /locus_tag="IXR05_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAQ4258842.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
BASE COUNT        28465 a        14604 c        17893 g        25357 t
ORIGIN      
        1 ccgttaatat acataagtga aagcgtttta tataagaact tgaaaagaaa gaagggatag
       61 acatgaaaaa aagatacaaa ttggtgatag ctttgctaaa cattacccta ttattcagct
      121 taagtgcatg tggaaaaact aacgaagaag taacagcaaa catcgcagat ccaatgataa
      181 aaaaagccac tacattagaa gtatatgtcg caaacggcaa actgacaaac tatgttgaaa
      241 atgctgcaaa aatctataac cgcaaaactg gagcaaatat tgacttaaaa attgtgaatg
      301 tagcttcggg aacagcaaca gtacaaatga tcaccccaaa attggtaaca cacgaagata
      361 tgccggatat tatctccatg gcagacactt cagcagcagg tgtgctggaa aaatttcaag
      421 atgcttttta tagtgctgat gaatatggat tttatgacaa atatggcgat cagttttatg
      481 atcaaaaatt gaatattttg cgtcaacaaa cgagtaatga aacgattatt ccttgggcta
      541 gtgattttac cccagcactt tgttattatc aaccaaaaaa atttgctgaa ataggtgtag
      601 attttgaaga aatcagttct tgggaagaat atatccaggt ggcaaaagca ttaaaagaaa
      661 aaactggtag ttttggaatt gccttgccag aatctgggga ccaagaattg tttatcaaca
      721 tgctagccca gcagaatcaa tctttgcttg atgaagaagg aaatatccgt ctgaatacta
      781 aagaagcgaa acatgctgca aagttaatca aagaaatgat cgactcagat attgtacatt
      841 tctacggtgc acaagatgct gagaaagcat ttcaagaatc tgcaatgttt gttgctggcg
      901 gctggtatgc tacgaatatg tctttgaatt ttcctgatgc atctgacaaa tggcgcatgg
      961 ctccactgat tcctttttca aaagaaaatc caggaaaagg tgcagtatca ggaggatcaa
     1021 gtttttatgt ccctaaagat gccaaaaatc cacaagtggc acaacaattt cttacattta
     1081 tgctgacaga tgaagaatgc ttagccaacg cactggagct gggcgtggct acatctaact
     1141 cattggccta tcaaacagaa gcagctgaga aaaagtttga ctactaagga ggacaaaaat
     1201 actatgaact attgaataaa atcaatgaaa atacatcaaa tactgtttta ccagccactt
     1261 attcagatgc tacgtcttat ttgactaccg ctgcatataa ctattggcaa acaggtgatt
     1321 ttgaaaattc atatctaaaa gaagcagaaa attttgctca taagtacggc gtaaaattaa
     1381 ctggtgatta aaaaatatta ggaggactta acgatgatgc aatcttcgtt accaagcaag
     1441 acaataaaga acagcaagaa aaaagcaaca gatacgtctc ataaaaaaag tgcttatgga
     1501 ttggtcacac cttttgttat tttctttatt gtgacgattt tgattcccat cattatctcg
     1561 tttgctttta gttttatgaa aattggctac tcatttgaat ttgttggatt tgacaattat
     1621 ctagctatct tccgagatcc attgtttatt aaatcttaca cgaatgtttt gattatcatg
     1681 gcaggatcaa ttccaataac gatgctatta gctatttact ttgctgtttt attgaattca
     1741 gcacagttaa aaggaaaagg attttttaga actgtctatt atattccaac cattacatca
     1801 acggtggctg tagcttccgt attcatgact tttttcaatc cgactgggtt attcaatgga
     1861 tttttgaatg cgctaggaat taacggtgta cagtggttaa caaatccttt ttggatacga
     1921 atatcaatga tcatcacgat gatttggctt agtgtaggat ataacactat tttattttta
     1981 gctggtcttc aagggatttc taaagagata tacgaaagtg ctgaaataga tggagcatcg
     2041 aaatttcggc aattcttttt attaacgatc cccatgctaa agccaatcat tttaatggcc
     2101 acagttttag ccactatcaa tggcttgggt aatttcaata tcccaaatat attctttggg
     2161 acttccaatg gaccagaaaa ttcagctttg gtcgtaggag tcaatttata taaaacaagt
     2221 tttgaaatgg ttgattttgg aaaagcctct gctattgcct ggacgatggt gtttgtatct
     2281 gttatattat cggctattca atttaaattc ggaggtgata aaaatgacta aacaaaagat
     2341 acaaagcaga atttttacgt acgtcattat tgtgtttggt gccttaatat ttttgatgcc
     2401 atatttatat atgattgtag cttcaacgca aagtaatcaa gaaattttaa gtggcggaat
     2461 caatttcaag tttggggata tgctattaaa aaactggcaa gccatcatgg cgagatataa
     2521 ttatcccttg attatttgga attcgattgt tattgctgta atcagtacag ttttagctac
     2581 agccagttct acaatggcgg gttatgcatt agcaaagtat cgttttatgg ggaataaact
     2641 gttgttcaat acagttatgc tatctaggat ggtgcctttt tttaccacat tgattccttt
     2701 attttacatt atgagtcgtt taggattatc gaatacttat gcaggtgtga tcatcccttc
     2761 gattgccagt acaacttcag tgtttatgat gcgacaatat agcagtcaat ttcctacagc
     2821 actgatggag gctgccagaa tcgatggtgc caatgagtgg gtgattttta cgaaaatcgc
     2881 tgtaccgatt ttatcaccta cgattattac tagtggttta cttatcttta tgggaagttg
     2941 gaatcaatat ctatttccat tagtcatgct ttcagataaa gataaatata cggttccctt
     3001 aattatcaaa aatatgacgg tttctagtac aggtgagcca attaattatg gcgcaattat
     3061 gctaatttta gcaacttcag tgatcccaat ggtcttgatt tatgtgtggg cgcagtctaa
     3121 atttaaggag aatgacattg gagctgcaaa taagtaaaaa aaataacgaa tgttaaccat
     3181 ctagttcgtt ctaggagcaa ctccacattc ataaaaatta aaagaatggc gggatatcca
     3241 tgaatgaaca gacgaaggaa tggtcaagaa aaattttgaa tgtagcttct gaaaagatag
     3301 atgcggaatt agacagaatg gggaataaaa ttccatatat ttcttacaac ggaaaatata
     3361 cagacgtaat aaaggacaga ggaatcgact ggtggaccaa tggtttttgg agtggtattt
     3421 tatggcagct ctttcacaag acaaaacgag aaaagttcaa agaggcagca atacaacaag
     3481 aacaattatt agaatctgcc ctgtaccatt tttcagacgt tcatcatgat gtaggttttt
     3541 tattcttacc atcggctatt gcacattatc aacagtctca aaacaaacat agtcgacaac
     3601 tagggttaca tgcagctacg gtacttgctg gacgctataa tatttcaggg aactatttag
     3661 tagcatggaa tgaccataaa cctggttgga tgattattga tagtatgatg aatttaccat
     3721 tactgtattg ggcttcgagg gaaactggtg atccgaggtt ctctaaaatt gctcggcagc
     3781 atgcagatac aacagctaag tatctagtga ggaaagatgg atcaaccggg catatcgcag
     3841 aatttgatgc agaatcaggg aaatatattc ggttacttgg cgggcaagga tacaatgaga
     3901 attcttgttg gagcagagga aatgcatggg ctttatatgg attcgcgtta agttatcgtt
     3961 acacaaaaaa tccgtactat ctagctatag cagaaaagat agcagtaaat tttattcaga
     4021 aaatcgaaaa aactggttat attcctctca ttgattttgc tgtaaaagat tcgaatattg
     4081 ataccagtgc tggagtatgc gctgcatgcg gtcttctgga attagcagga tatgtttcct
     4141 ctgtacgatc aaaaatgtat catgaagctg ctatcaatat actccaaaag acagaaaagc
     4201 actatgcaaa ttggaatatg gatgaagatg ggatcattgg aggcggagca gaagcatacc
     4261 atagagaact gacttataat gtgccactga tctattctga ttattttttt attgaaggct
     4321 tacttcgatt agaacagtcg gaattagcta tttggtagta aaaagaggag aaaatacaat
     4381 gaaacatcca gtaccactat taaggaccag acaggattac tttgacttat ttaaaaagat
     4441 aaatcaacca ctccagccgt tttatcgagc aagtggcgca caaattgatt atatacatca
     4501 aggggtagga tatggaaata aaattgcagg aatggaagga ttctctcggg ttttatgggg
     4561 agcggggccc gcaattgacc aattagatga acgatggttg aaattaattc tatcaggaat
     4621 aaaagctgga acagatcctt cccatcccga ttattgggga gaaatacatg aaagagacca
     4681 gcgtatggta gaaatgcccg caatgttatt agcgttatat catcatgaac aattattatg
     4741 gaaaaaatta gatacaggag aaaaaagcca gattattcat tggttctcgc aaatttttga
     4801 atatgaatgt gcagatggta attggcaatt ttttaagata attgtcggaa caattatcca
     4861 aaaatttggt tatccagtta aagaatcagc actgaaagaa gcatttgata atatagaaaa
     4921 ttgttatctt caaaatggct ggtatcgaga cagttcaaga ggtcgccaag attattataa
     4981 tccttttgca tttcattatt atggtttgat ttatagcgta ctagaaccag aaaagcccat
     5041 tagccagata tataagaacc gagctattga tttttctaga gactatattc atttttttgc
     5101 ggaagatggt gcaaatgtgc cttttggtcg aagcatgatt tatcgttttg cagtttcaag
     5161 cttttggtca gctatgttgt gggccgatct tttgcctttt aaattaggtg aaatcaaggg
     5221 gttagtcaat cggaatataa gatggtggat gcaaaaagaa atatttgatg aaaaaggtat
     5281 cctgaatatt ggttatacct accctcaatt gacattgact gaaccctata atagtacgtt
     5341 atctccatta tggctgaata agattttttt attgttggcg ctacctgaag accatgagta
     5401 ttggacggct aaagaaatgc ctatgcctat tcgtgaagga actaaacttc tttcagaagc
     5461 caatttgctc atacaacatg ataatggaca tacatttttt ttgaatgcgg gacaattagg
     5521 gccaaatttc catacattga ccaatgaaaa atatttaaaa tttgcttatt ctagtcaatt
     5581 tggtttttcg ataccgcgag cgaatcaatt gaaagcagaa atggcaatgg attcaatgct
     5641 agggattcag cgagcggaca catatatcac gaccagtttt aagaatgaga gcatcaaaac
     5701 ctatggacag ttcatcgttc gaaataatgt acgagacatt gtatgtaaga aagaggtact
     5761 tgcctctaca tgggaaccta ctttacaggc aaaaatcaga acttggctta ttccttttga
     5821 aggctggcag attcgcgtac acaaagtaga attagataca gaatatgttc tatatgagac
     5881 agggtttgct attgaatgtt ctcctgagaa agaaggaata atcatagaag aagacaagga
     5941 aaactatagg gtgagtgaag ctggcttttc aggtattatc tgtttaagtg acgatactat
     6001 taaacgaaaa tccacagcta ttatgggttt gcccaataca aacttgatga catgggaaaa
     6061 cacttttatt cctggattag agggtacatt tggaaaagga acccattggc tcggaacagg
     6121 agtggttgct catcaagatc gggattatag tttagaagta tggaacaatc gtcccaaaat
     6181 tgattttgat gggacaaccg ggctaactat ccaaaataaa aacaataaaa aaagactaaa
     6241 attatgctaa aggctggtgg ggaaatgctt gataaagtga tgtttgaaga gataatacat
     6301 ccagaaaaat ggataaatga atgttataaa gaattaatgg aaaaagaatg gaataatgag
     6361 atcgagcgtt gtcgcagaca cacggagagg ttaatcaaac gtatcagtaa cagtcagtat
     6421 caattcccaa gcgagtgtcc tataaaagga cgttatccat taagagacaa tattggttgg
     6481 acagaaggat tttggacagg aattaattgg ttgttatttg agaagacggg tgatccttta
     6541 tttcaacaaa cagctgaaaa agcagatata gattttatcc acaggattga ctgtcaaatt
     6601 atcactaatc atcacgatct tggttttttg tattctttat caaccgtagc agattataaa
     6661 ataacgggaa atcgaaaaat gaaggaagct tcaattgatg ctgcagaaac attacttcag
     6721 cgtttttggg agaaggcagg agttatacaa gcttggggag atcctagtga tccttcacaa
     6781 caaggtagaa tgatcatgga ttgttgcatg aatcttccat tattgtattg ggcgagtgaa
     6841 gaaactggaa atcaaaaata taaaaaagct gctcaggctc atattcaaaa tgcagcagat
     6901 tatttagtaa gagaagatgg ttcaacttat catacatttt atatggatgt caaagatgga
     6961 aaaccaagat atggaagtac gcatcaaggt tatagtgata attcctgttg ggctagaggc
     7021 caagcatggg ggatttacgg ttttgcatta agttatcgtt atttgaaaga acaaaaatat
     7081 tttgatttaa gcaaaatatt agccaattat tttatgaatc ggttgccaga agataccatt
     7141 tgttattggg atttgatctt tgatgattct agcagagaag aaaaagatac atctagtatg
     7201 gtgatcatgg tttgtggatt attagaatta atagaatcag gtctattaga caaaacagaa
     7261 aagaacttat accagtctgc tgtttggaaa attatgcgac aattgaaaga aagatatgct
     7321 acaacggaag aagaagatgg ctttttaaca cagtctgttt ataataagcc caaaaataat
     7381 ggggtaaata caccttgtat ttggggtgat tactattatt tagaagcttt agtgagaatg
     7441 actagtaatt ggtcttctta ttggtgaaaa aggtaaatat ggaatttttg tttgataaaa
     7501 taaaaaaaga aaaaccaaaa cagcatgaat ggtttctgtt ttggtttttt cgttaatttt
     7561 catattcttc taattccaag cttagttctt cccattccgt caattttgtt tcttgatctt
     7621 gtctagcagc ttctaaatct tggttcagct cattgagttt tacgtgatct tccaggtttt
     7681 ctggcgcgac catttcttgt tccaactgat cgatccattc atcgatccgc gccatttctt
     7741 cttcaacctg agtaattttt cgttgaaggc tacggataag cttttgctgt tctttgcttt
     7801 ggtaataatc agatttgttc gtgggagcag gagcagattc tggctcatct tgtgccaaca
     7861 attcggcgat ttcttcttct tcctgctttt tctctaaata ataatcatag tctcctagat
     7921 agactttgct gccattttca gagagttcga cgacttttgt cgcgatccga ttgatgaaat
     7981 atcggtcatg ggaaacaaaa agcagtgtgc cgtcataatc gatcaatgca ttttctaata
     8041 cttctttgtt gtcaatatct aaatggtttg ttggttcatc caaaatcaaa aaattttctt
     8101 tgttcatcgc taacttggct aaagcaaccc gtgctttttc accgccactt agcagaggga
     8161 ttggtttttc tacatcttcg ccagaaaata agaaagcacc taaagcactt cggatctctt
     8221 tttctggagt ggtaggatgc tcatcccaca attctgctag gatcgtcttg tttgtatgca
     8281 gatcagcttg accttgatcg taatagccga tggtgacatt tgtccctagc gtttcttttc
     8341 cacggataaa agggatctgg tgaatgattg atttcagcaa cgtcgatttc ccgataccat
     8401 tcggacctac tagagcaatc gcttcttgac gacggatatc tagattgatt ggttcagata
     8461 aggtgacatt atcatatccg atagcggcat cttcgatttg caagactaca tttccagaag
     8521 gcttttctat actgaataga aagtttgctt gtttttcatc cccttgagga cgatccagcc
     8581 ggtccatttt ttctaatgtc tttctgcggc tttgcgctcg ttttgtggta gaggcgcgaa
     8641 caaggttccg agcaacgaag tcttctaatt tatggatttc tgtttgctgc ttttcataag
     8701 ccttccattc acttgctaac tgttctgctt tcaaatctag atatttcgaa tagttacctt
     8761 tgtaatggcg catttttctt ctgcttaatt catagacttc attgactact ttatctaaaa
     8821 aataacggtc atgggaaaca atcaataatg caccagtata gctttgcaga taattctcaa
     8881 gccaggaaag tgtctcgata tctaaatggt tcgttggttc atctagaatc aaaatgtcag
     8941 ggtgttgcaa aagcatgcga gctaaagcta aacgtgtgcg ctgtccgcct gataaagtat
     9001 cgattttctg atcataaaat gaagaatcga atttaaaccc atgcaatacg gaacgaattt
     9061 cattttcata accatagccg tttcgatctg aaaaatcgtg ttgcagccgg tcgtattctt
     9121 ttaaataaga actataagca ggtgtgtctg gcgtaccttc gctaatgaaa atctctagct
     9181 cgcgcatccg ctcttccatt tgtctaactt gttcaaaagc tttcagcatc tcgttccaaa
     9241 ctgtttcatt ggaatcaagt cctgtgtcct gagcgaggta tccgagagtc gctgttttat
     9301 ttttagcgat ctttccttca tcaggtgctt caattccagc aatgatcttt aataaagtcg
     9361 attttccagc gccatttctg ccaactaaag cgacacgagc gcctgtactg atttctaaat
     9421 gtatgttttc aaataagact tctgcaccaa aatggcgagc aatctgattg gcttgtaata
     9481 atatcatgga atcctctttt ctactttgtg aattctcctc aaataaaaaa ctatttttca
     9541 attagtagtc taccataaat tccattatac tgcgagattt gcagaaatga taaataaatg
     9601 aataaagaat aaaatttcac aatatctgag caatggaatt gattttttcc tataaatact
     9661 gctatgatgg agaaatcaaa gatgtaatta gacaatacgt ggaggtcatt tcgtgaaaga
     9721 tcatattatt ccaaaggcga cagctaaaag actgcctttg tattatcgct atttaaggat
     9781 tttaaataat gctggaaaga aaaaagtgtc ttcaactgaa ttaagtgaag ccgttcaagt
     9841 agatagtgca acgatccgtc gagatttttc ttattttggc gaattaggaa aacgtgggta
     9901 tggttatgat gtagaagatc ttatgcactt ttttgcaaag acattaaacg acgatcaatt
     9961 gacaaatgtt gcgctgatcg gtgtagggaa cttgggaagt gctttactaa aatacaaatt
    10021 ccatcaaagt aatagcatac gtatcagttg tgcttttgat gtgaatgagg aaatcgttgg
    10081 gcgcatcgta gacggtatcc ccgtttatcc aatggaagat atgtcagaac aaatcaagat
    10141 ccaacaaatc gaagtagcaa ttttaacgat acccgctgaa agagcacaag aagtagtcaa
    10201 tcagttaacg gaagcaggaa tcaaaggaat cttgaacttt accgctgctc gattgaatgc
    10261 tccgtcagat gtattgatcc aaaatgttga tttgacgaat gaattgcaaa ccttgatcta
    10321 tttcttgcat tctgacgcaa atgcgcattc cgaaaataca gcagaataaa aataaaaagc
    10381 gattgaacaa atgaaggcaa aactttcact tgttcaatcg cttttttctg tttggacaac
    10441 gattattttg ttcggaagat ttcttcataa gaaagggaat catcttctgc tgtcagttca
    10501 tctagtagat aacggatttt tttaaagtcg atgaaccgtg cttgccgaaa gacttctttt
    10561 ccttgatgaa aaatcaggac aactggcgca gtcagcactt caaatttact agctacttct
    10621 ggtgtttcaa atgcatccaa atgaagtgcc ggaatatcat aatgtgtgag aagttcctct
    10681 agtcgtggac gaacagcgtg acaaacactg caattaggca tcgaaagata aatgacggca
    10741 acggatgact gttgcagtat gtcttgaact tcagtcaagt tagtggtttg tttcattttt
    10801 attctccctt ttatgataga agtgatatgt atgagacctt aatttaatgg gaataacaga
    10861 aaaagtcaat tgaagtgctt tggtaaaaaa taagagttgt gtaaaaattt acagagcaac
    10921 ttgttttttt tgaataaaag cgtatatttg caaagcgaat gaactagaaa taaaaaggag
    10981 gaaactcatg ttttctttta ttccaaattc ggttttgcag atgagtacga ttttcttatc
    11041 gatcgttatt gaagcattac ctttcgtatt attaggctgt cttatctcag gcgccttaca
    11101 agtatttttg accccagaac gtgtgaagag atggcttcct gaaaatcgta tcttctctat
    11161 ttttactggt tcgatcttag gatttttctt tccttcatgt gaatgcggca tcgtaccgat
    11221 cgttcatcaa tttgttaaaa aaggcgtacc agttcacaca gcgtttgctt ttatgctgac
    11281 tgctccgatc atcaatccaa tcgtgatttt ttccactttt atcgcatttg gcaattcttg
    11341 gcagatggca agctggcggg tgataggcag cttttttgtt gcccttgtga ttggtgtctg
    11401 gcttgcctat tttcaaaaag acgctgtatt gaaagaaaaa atcacgtcta aagtagcaga
    11461 aaatcaccat catcatgtcc atgaagaaga acaaagtgag aagaatgaac caaaaaatca
    11521 gctgatccat caaactgggc atgtgttgac acattcaatc gacgaatttt ttgatacagg
    11581 tcgttatttg atcattggcg gattaatcgc agctgcgatg cagacttatt taccaactag
    11641 aattatgcta acgctcggct caacaaagat tttagccatt atcatcatgc tgttattggc
    11701 ctttacgatg tctctttgct cagaagcaga tgcgtttata ggatcttctt tgttaagtct
    11761 gttcggcaca gcacctgtag ctgccttttt ggtctttggc ccaatggtcg atatcaaaaa
    11821 tctactgatg atgaaacgat attttacagg acgctttatt ttatcgctga tcggactgat
    11881 tgcccttagc gttattggat tcacattatt tatttaggag ggaaaatatg ctgcggtttt
    11941 tgattttatc tgggtatttc gaattgatga tgtacttgca agtttctggc aaactcgatc
    12001 aatatatcaa tgtccattat cgctacttag ctattctttc aatgatttta tctgctcttt
    12061 tggctttagt tcagctgtat ttgtgggtca aaaacggaaa agcagaagaa aaggcacacg
    12121 agcacgatca tgaccatggg ttgtcaaaac cttatcaacg tggaatcgct tatgtactgc
    12181 tagctttgcc agtaatcgtg gggacgttgt ttccaacagt tagtctcgac actacgatcg
    12241 tagaagccaa aggatttaat ttcccagtaa gtaaagaatc agtaggggat ccggagatgc
    12301 agacacaata cttaaagccg gataccagta tttatttcaa caaatcagac tacttagacc
    12361 aaatgaatga gttgaaagaa aagtatgggg ataagcaaac tatcaagatc acagatgaaa
    12421 actatttaga agttatggag ctaatttata attaccctag cgaattcatt ggcaaaaaaa
    12481 tcagctatga aggatttgtt taccaaacac cgaacgatag caatacagat atcttcttgt
    12541 tccgattcgg cattatccat tgtgtggcag attcaggagt ctttggtttg ttgacgcata
    12601 tgccggaagg agtaacggtt aaaaatgatg aatggtataa aatagaagga accatccaat
    12661 cagactatta tcaaccattc aagcgtgaaa tcccatctgt agttgttaca aacgctgaga
    12721 aagtctctgc tccgaaaaat cagtatgtgt atcgttcttt ttaaaagaac aaaataaata
    12781 aacatagctc agacagctga cacgcaagga cgtcggttgt ctggcttttt ttgcatgatg
    12841 tattcatttg tttgatattt attttagaag cagcatcctg aaagtatttg atatcggttt
    12901 caaaggtgtt ggaaaagatt gtgaagagaa ttacaattta ttcctaacat gtatgttgaa
    12961 aagttgtatg aaatgatttt gatagtaaaa tatcgagtgg aggtactttt tatggtaacg
    13021 cgtatattta ttttggatga tagtttggtt tttgaaaaaa tgctagtaga aattttggaa
    13081 gaatccagaa ttttattaag tccttggaaa tttgagatcg ttcagggatt gaacgttata
    13141 caatttgttg aattcattaa aaataatgaa atctattcct cagatatttt tttcctagac
    13201 atcgatttga acgcctatta tagcggtatc gaactaggcg aaatgcttag agaaaagaat
    13261 gaaaagtgta aaattgttta tctaacgtct catccgaata aagcaataac tgttattaat
    13321 cgaaagatta cgcctagtgg ttatttgata aaagaattca cttatgaaaa aaataaaaaa
    13381 agcatccaaa gttacttatt gaaagaaaaa gaaaactatc ctgttcaaca tgctacgaaa
    13441 aaaaggtgga caactgtccg ttatggtaat agcgatcact atatccatta cgatgaaatc
    13501 ctttatctaa tgagcatgcc aggttataaa aataaaatag gcctagtatt gaaagatgaa
    13561 gagattctcg taaacggcac aattaaaaaa tataaaaaat cactcgaata tgagtattta
    13621 tgtaaagatt taaaagctta tatcattaat actgaaaaca ttacatctat tagcagagta
    13681 aacgaaatag taacatttgc aaatggagaa caactagaga tgggaaagag aagtattgat
    13741 aaactaaaga attttatgca agaaaagata gaaaatgaat cattttaaag aaaacaaaga
    13801 ctcatatctt acctgttaga agagtgtttt cctgtagaag agaacaaccc aagtagcagc
    13861 ctagtcgttt ctatcctttt ttgttatgca ctctttttga catttactcc accaataacg
    13921 aagggtacaa taaaaagtaa taacaaacaa aaggagtaca gaaatgattg aattcatcaa
    13981 tgtaagtaaa agttacggga aaaaacaagc attaaaagac ttgtctctct cgataagaca
    14041 aggggaaatt tttggatttt taggacataa tggtgccgga aaatcaacta cgattaaaag
    14101 tttagttagt attattgaac catcatcggg aacgatttta gtagatggaa tgaaattgac
    14161 ggaaaatcga ttgagtatca aacaaaaaat cggttatgtg cctgattccc cagatatttt
    14221 tttacaattg acggctggag aatattggga cttgatttca gctgcctatg aattagacac
    14281 acaaaaaaaa gaaaagcgtt tagcagaatt gacagcgctt tttgatatgt atagtcatca
    14341 aaatgaaaca atcgcaagtt tttcacatgg aatgcgtcaa aaaacgattt tgatcggcac
    14401 gttgctgcca gatccagata tttgggtatt ggatgaacct ttgcaaggac ttgatcctca
    14461 agcagcattt gatttgaaag aaatgatgaa ggctcatgcc gcaaaaggaa aaacagtcat
    14521 tttttctaca catgtattgg ataccgcaca acagttatgc gataaactgg ctattttgaa
    14581 gaaaggtgaa ttgatttatc agggggcagt tagtgaatta ttgaatggct cacctgatga
    14641 aacgctagaa aagatttatt tgaaaatggc tggaaggcaa gcgacaggag atggaccgta
    14701 tgtataagcg acaattatta gaattaattc gagttaatct tttatatgtt aatccacagc
    14761 tcacgaataa agcaagagag aaaggaaaaa agggaaagcg attaactatc tatcttttgt
    14821 ctcaaaatct tttttcaggg ctgatttttt tactgattta cggatttgct atgtttgcta
    14881 tgaactttgt taaattgcca ggtttcttta cttattacgt ggcacttttt ggtatgttag
    14941 gtttaactca aagtatatca gtcatttata atatcttttt tgaaggaaat gacctgcaag
    15001 tatttttgcc tctgcctttt ggacaagaac aggttttttc agcaaagatt ttggtagttg
    15061 ctttgaccat cattcctttt gtttttccgc ttctagtcat gtttatttta accggatggc
    15121 gagctgatct agggattttg cttactatca ttatctcaat ccttttgttt tctctatttt
    15181 tgattattct tttttgtctg gctagtttga ttgtttttgg tttggctcga acagcagtgt
    15241 ttaaaaaaca tagaaaaaca gtttctagta tcttgcttgg cagctcgatg ctgatcgcat
    15301 ttgctggaat catgtggatg aatcatcaaa cggggactat tgaaaatgag ttaacagatc
    15361 ggcatccgat ttcgatatta ttgccattct atgatgctgc cagtcagcca ctttctcaac
    15421 aaggtttatt gggttgggga atactagcta tcacggctct gggatttttc cttgctgtaa
    15481 aacagctgat agtaccaaag cttacagagc aactgactga ttcaaacagt gagttcaaaa
    15541 taaaaagaac ccataaaaag aaccaaaatg tgcatcagct tttatttagt tacaatgctc
    15601 aattagtaaa agaacctaat ttgattatgc aagttctttc ttcttccttg ttaactccaa
    15661 tcatttttat tcttgctttt gccctaggag gcgaaataaa attaactgat ttagataata
    15721 agttaatcgg tgttgttttc ctggtaggga tcgcattggc tttcttaaca gttaatcaga
    15781 cttcttttat cagcaatctt atttctttgg atcaagaaaa ttttctgttt atccgttctt
    15841 tgccaatctc tatgaaccaa tatttaaaag aaaagttcag attcggatgg atattgcaga
    15901 gttttttaac tggtgggatc gcattattaa gcggactgtc ttttcagctg cctttgtttt
    15961 ttatccctag cttgctattt ggttctttat tcggctgcta cttattgtca ctacgttatt
    16021 tcgctagaga ttatcggttg ctgctgctga actggaccaa tattaaccaa ttatttaaca
    16081 gaggttcagg aagtttgggt ttagtcgcaa ctatgatggg ttcattgatc atcagtatta
    16141 ttcttatcgt cttatacgga atgttggctt tgttttatcc attttggtta gtgaatattc
    16201 ctgtgatcgg tttagttcta atactttccg ctctatggat cgtttattat caacgaacgt
    16261 tttggaaaaa atttgaataa agaagagggg ccgtgacaaa aatcatgtcg cagccccttt
    16321 tttacagata gagggtgttc aaaagtcagt ttctcagtat taagtcaatt ttatgtaaaa
    16381 atgtgagaag ctatttttac aaaacttttt ttaatactca taattacttc ttattgctcc
    16441 tgcggttact tgtcgcaatg tttgtgagat attttgtcat cgctcaaggc tgaacgtctc
    16501 tttcacaacc ttttctttgt tacacttcgt ttatttaaaa agccgttttt ttcgtttcat
    16561 catgattgcg tcacgcttta ctttgaaatt acggatgtta tggttaaaga cttctgataa
    16621 tacaagacct aaagcgattg ctccagcaat cataattgct tggaccgcat aatgagccgc
    16681 ttctcgatag gattcagtaa cgagatttcg aaccgcttga taagctaaac caccagggac
    16741 tagaggaacc atcccgggaa tattgaaaat cgttacgggc attttcaaac gtttagagaa
    16801 aagatcgctg atgaatgcta ctcctaaaga accaagcaat gaaccaaaag cagcagatcc
    16861 gcctatttga acacagatcc agtagatcat ccagccaaaa gcaccagaaa gaccacaaca
    16921 aatcaatgaa cgcctaggta catttgtaat aacggcaaat gccgcagtcg ctaaaaaact
    16981 aaaagaaaac tgaataaata tcgtccccat acttgtgttc ctttcctaat aaaaaagctg
    17041 gaaaataaaa gcaatcgcaa aaccgatcat cgtagcagtc atcatcgctt ctgttccgcg
    17101 agaaactcct gagacataat gtccagctag caaatcacgg atagcgttcg taatttgaac
    17161 tccaggaact aaaggcatca cacatccgat aatgattaga tcctgattgc ttcctaagcc
    17221 aaaacgtacg ctgtagatag cggctatgcc aatcaataaa gaagataaaa attccgataa
    17281 aaatttgatt ctaaaaaatt tcaaactata tagataagct gcgtatccca atcctccaat
    17341 gactaaagtc acaggtaaat cggtcatctt tccgccaaat aacaccataa ttgttccact
    17401 gatcactgcc gcgctaacga tttgcaacca gacaggaaag aaagaacggt ctcggtcgat
    17461 tgcttgcagt tcgcagtaaa gttcttctaa tgttagctct gaagcaacat atttacgtga
    17521 aagatcattt acttttacta ctttttctaa attaatcgaa cggttggtaa tttgttccat
    17581 tcggatggtc gaggtacgat caagaccaat aaagagaccg gtttgagtga catagctgac
    17641 caaacggaaa tttccagaag ctaaagcaat tcgactcatc gtatcttcta cccgatacat
    17701 ctccgcattg ctttccatca tgattttccc agcgagtaaa caagtgtcca gcaacagatc
    17761 taattctttt cccgtcatag catcttctcc aataattgat tgattagttt tattttacta
    17821 caaaacatac cagaagcgta aagaataaaa aaacttgagg aaggaataaa agaggcgtat
    17881 actgtttttg tattgcgggt gtagtttagt ggtaaaatcc cagcttccca agctgatgtc
    17941 gcgggttcga ttcccgtcac ccgcttaaaa taggttgtga aaaagctgct ctgcaacaag
    18001 taataagaac agccaagcaa aaacaacttc ttatgttttt aacttggatg gacttattac
    18061 cgcagatgca agcttttgcg caccgtttac caagcggttg tgaaatcagt gtattgtctt
    18121 gagtatgaag aaaatttttg aataataata aataccttac agatagagtg gtgactgatt
    18181 agagacgagg aatccgtctc ttttttgtat ttttaagcca tcttaaaaca ggttttattt
    18241 tttgctgttt ctatttcttt ctagtattta tttatagggg aacatatgtt aagatttagg
    18301 gagctgttag taaaggagta aagaaatgag caaaaaaaca accaaggcga tcgtggggat
    18361 cgtcgctgct gtgattgcag gggcattcgg tgtttccacc acacaaaaag attcagatat
    18421 ctttcagcag attacaacta tttttgattc cacaccacaa gcttctcaag tagcggatgt
    18481 gccagaatat gatggaaaac atcaagaaat agaaatcaat gggaatcagc cggaatttac
    18541 aaaagaggat cttagccttt ccaaaggaac atgggaaagc tattcaaata ttgataaatt
    18601 gaacagagta ggacaagcca atgctatgct tggaaaagat ttgttcccta ctgaaaagag
    18661 agagcctttg tatattgacc cgacaggttg gaaacaaaag aaattaagtg acgggcaatg
    18721 gttatataat cgcagccatt taattggttt ccagctgact ggtcaaaata acaacattaa
    18781 aaacttgatg acagggacac gttcgttgaa tgctccatac atgcttgctc acgaaaatga
    18841 tattgcggca tatatcaaag aaacaaatca tcatgtacgc taccgtgtca ctcctcattt
    18901 tgaggggaat gaactggtag ccaggggagt gcaattggaa gcagaaagca ttgaagacaa
    18961 aaaaattgaa ttcaatgtct ttatctacaa tgttcaagat ggctacacga tcaattatga
    19021 gacaggacaa gcaacaaaaa caaaaaatta gtagcagcta ttcgaatttt ttatgaatat
    19081 tatgaaaaaa ttgtgtaaaa acatacattc aaagaaatat agcgtatact ttatgaaaag
    19141 agtacttttg ataaagctac agaaaaaagg aaaaaaacat acaaatagtg tttcttaatt
    19201 tattcggaag tttggaatat ttgtttgtag ttttcccttt cttcgagtaa aataaggttg
    19261 tagaaggtaa gctggaatta ccttgcggga aagaggtgta gaatcatggg ttttacagat
    19321 gaaaccgtac gttttggttt tgacgatagt cgcaaaaaag aagtgagcga aacattagcg
    19381 attgtttatc gggctttgga agaaaaaggc tacaatccaa tcaatcagat tgtcggctac
    19441 ttgctttctg gagacccggc ctacattcct cgttatcgtg atgctcgaaa tttgattcgc
    19501 cgtcacgaac gcgatgagat catggaagta attgtcaagg actacctctc aaatcatgga
    19561 gtgaatttat gagagtaatg ggcttggatg tcggttctaa gacagtaggt gttgctatca
    19621 gtgacccctt tggctggaca gctcaaggag tagagatcat tcggatcaat gaagcagaag
    19681 aagagtttgg ctttgatcgg ttgaaggaat tagtagcaca atatgaagta gaccggtttg
    19741 tagttggatt acctaaaaat atgaacaatt ccatcggacc aagggcagaa gcttccatgt
    19801 catacggaga aaagatcaaa gaactattct ccttgccagt tgattatcaa gatgaacgat
    19861 taaccactgt tcaggcagaa cgtatgctag tagagcaggc aaatacttca agagccaaac
    19921 gaaaaaaagt catcgataaa ttagcagctg tgatgatctt acaaaattat ttagacggct
    19981 caggtaagca attattttaa taataaaaga aaagaggtaa tcttatgaca gaacataacc
    20041 attcccacga ccatgaagga cacgaacaca tcacattggt ggatgaccaa ggaaatgaaa
    20101 cattatatga aatcctacta acagttgacg gacaagaaga atttggacgt aactatgttc
    20161 ttttatatcc tgctggtgtt tcagaagatg aagatgtaga attacaagct tatgcataca
    20221 tcgaaaacga agatggaaca gaaggcgagt tagaacaaat cgaaacagac gcagaatggg
    20281 acatgattga agaagtattc aatacattca tggcggaaga agaagaatag actataaagc
    20341 taggagaaac cttgatatga tagggtttct ccttttttta ttttttactg tatgccatat
    20401 tgtatgccat ctagtcaata tttaagtgtt gtactaattt ttcaacagtc ttttctttcg
    20461 tttcttttgc caagtgaccg taacaatcga tcgtctgact aatttttgta tgccgtaatc
    20521 tagtttgaac ttctaccata gtagctccag cgtccaagag cattgaagca tgagtgtgtc
    20581 ttgctacatg cacaccgaga aatggaacca tagctttttc acaaatagta atcaatcttg
    20641 cataaatagc gtggtgtgtg attagttctt tatagatacc acaaaaaatc atagtcggat
    20701 cagttacacc aagtgtcagc atatatttcc gctgattaat ctgccatttt tttaatatag
    20761 aaattgttct ttcatctagt ggaagaaccc cagcactaca atcagtttta ggatcactga
    20821 ttttatagcc atttttggat tggcttagtg ttttattgat ggtgaccgta ttttcttgaa
    20881 aatcaatgtc tgaccaattc aatgcaaggg cttcactgat cctaaccccg ctataaaaga
    20941 gaaagcgtag taacgtttta tcaaagtcgt ttcgataagt ttcaggtttg ctgtttaggt
    21001 aatcaaacaa ggtgatcagt tgttctttac tgtaaacttt gaccttttct ttatgcttag
    21061 tggtggttct tttaggcatt aatacgttgt ctagtggatt agtctcaata atcccaagat
    21121 tgatagcgta gctaaaaata cgcttagaag ttgaatgaag taccttgtat tggtcagtag
    21181 tttcagccca gctatttaca atttgttggg ctttttttac cgtgacttca ttcacacgaa
    21241 gatttccata ttttggaaga atccactttc taaacttgat ttcagttttc atgaaggtgg
    21301 cttctcggac agtggtttta tatgtttcta gccacaagtc ataaacttct ttaaacgttt
    21361 cgttgttcgc ttttttaata ccgtttttat cgtagtccac ttgcaagcgt gacaaggcaa
    21421 gctgggcttc tttttttgtt ttgtaacctc gtctacgaac cttatcaggt ttgccagtca
    21481 ttttgttcat tccaagatag gcttcataga gccaaaattt acctttttta gtttcatatt
    21541 gcttgaatgt tgccataata gttttccctc catagtgtag caagccgtgg gggcggttgg
    21601 aggaggcagt ttattattat tttgaatagt gtttatttag ctcagtaaca agagctgtga
    21661 actcttttag aagatcattt tcataaaatt cttgatactc ttttttctca tctgtatttt
    21721 tttctgaatc attaattaat gagtcatatc gtaaaagcgt atttagaaga gctgcgagat
    21781 aagcaattgg ggtactcccg tcaggaaatt caattcgaga tcctgtttta agatatttta
    21841 ttgcgtttgt taaataaatc ttctgtgaga cagtcaggtt atcttcttcg atgttattga
    21901 tagcattaga aagattagaa tcaattatag agttattttt ttcaatagtt tttttcaatt
    21961 gcttttcaag cacatttcgc ttaatttcgg gcatcatatg catatctctt aatgtataag
    22021 atccgtttaa tagataggta gtggatacat ctaatacctt tgaaagttgt ttaagcctgg
    22081 tgttattggg aagattatag ccattttccc aattactaac ggcaccttta ctggccggtg
    22141 gggataattt acctccaagt tgttccattg agagtccctt ttcaattcta gccagtctaa
    22201 ttctttgtcc tgtctccact gcttcggggt atttttttct agccacattt tcaccaccat
    22261 tcatatattt tctctactat atcacgattt aaatatgtgt gaaacataaa agttcaaaaa
    22321 agtatgttaa aattcttgca aatgaaaagg tatgatggta tattgagttt ataagaggta
    22381 tagaaatgta ttcaagagcc tcttgcattt ttttaaaatc tttgtataga aatgtatgct
    22441 aacgaggggg gataaatatg gaattaaaaa ttgacaaact cacgcttgat gatccagctt
    22501 ttaaaattat tgacgatcga gttgttcaac aagtagagca aactcaagga acgttacttt
    22561 cattattaga aaaaaagtac cagtttccaa aatatatgaa caaggcacaa gctgctaagt
    22621 atatgaacgt ttcatacaat actatgatgc agaaatatgt tcctaacggt ttaaagttga
    22681 ttatagttga tggagtcgta agaatttcac aagatgaatg tgatcgcttt atggaagaat
    22741 accaaaaata aacgcaagcc gtgggggcaa agggattaat aggaggaaat aataatggaa
    22801 tcgacacaaa ataaagcaat cgaaaaagta ttatcaacaa ttcttacaga agacacagcg
    22861 gcagaattag caaacttgga aggcaaagcg ctagaagaaa cgtttgaatg tttgtacgaa
    22921 caaatggact atcaaaaatt gctaccacaa gaaccaacgg taagcggagt attgcgtggc
    22981 ttgaacgatt tagtacaagc agagtttaaa gaacgacttt ctattgaaga gtatcaagaa
    23041 attttgtatc agcaagttga gttgttagcg agcttgctag ggcttgaact ggaggacgtt
    23101 gaatgaaaac tgaaatttgg aacggacaca ttataagatt tgtcgatatt aatgatgaat
    23161 ggtgggcagt ggcgaaagat gttgcggaag cgttaggtct taaacaggtt actagagcca
    23221 ttcactcttt gcctaaagat ggggttacta ctagtaaggt catcgattca ttgggcagaa
    23281 cacaagatgt aaacatcatc aacgaaaaaa aatatttacc gcatggcatt caaaagccgt
    23341 aaaaaagaag ccgaggcatt tcaagactgg attttcgaca tcatcaaaga actacgccag
    23401 tccacaggac ttgaaggctt tcaagtattc cgcatgctag acaaagaaca ccaaaaagaa
    23461 gcaatgacta aattaagcca cgctattact gaaccaaaac cagtagacta cattaaagcg
    23521 aatgtgatag ccaataaagc tgtatcaact atttatggtc attccaaaat ggtaaaaaag
    23581 aaagatatga ctcctgaaat gttggttgat cgtgaaccta ttttagatga gacagtagaa
    23641 ttaatgactg ttaaagaaaa atatgggttg cagttttcag tgagtgagaa aatttataat
    23701 cgttctgctg aattgcagac aacttaggag cattaacatg atcgagaaca aagaaaaagc
    23761 cttatccata acagtcttgg cggacaggat aaaggcaact taattgggat aaaacccgat
    23821 attctttgtt ccgattatac catattaaaa aatcggaggg aaccattatg aaacgaaact
    23881 taattatagg aagcatttta atcggcggaa ttttcggctt attaccatta attgcaaaaa
    23941 tagctatctt tgcaggatta gcgttatatc tcttcactgc ttatgacgag tacgactatc
    24001 aattaagaac tggagggcat aagtagatgt acaaaacaaa actattaaac caactcgata
    24061 gccttgaatt agaggaaatt aatcaaggga tcgctgaact agaaaataat atcgggaaaa
    24121 cctactttgg aaattcattc aatgaaaaac taacagtttt gtatgtactc aaaaaacatg
    24181 cagaacacaa aataatttgt cgagaaatca acgagctaaa aaatcagatt ttaaccgcat
    24241 ggttaaacat tactgatatg caagaagcaa gggtgaaaac atttaataca tgggtaaagt
    24301 atcagaatca attaaaaggt gctgaatttg ttcgggatgg gttgaaatac gaacttgagc
    24361 agttgaagct catggaggtg tctgaatgat ttataccagt attttgaaaa aggaggagag
    24421 gtttattggc aaataattat caagcagcaa cggaattaca aaagtcggga tggtcaattt
    24481 atcccttatc tcctggaact aaaattccaa taaaaggctc tagtggttgg aatgatgcaa
    24541 ctaacgattc taatcaaatt aatgaatggt ggacggaaga tgcaactaga aatattgggt
    24601 taatgcttga agatcatcaa atggtggtag ttgacctaga tcaacattct gaaacacgaa
    24661 acggcgttga gaattataaa aaacttgctt caatgtatga tccatttcct tctacttata
    24721 cggaaatcac accaggtaaa ggaatccatt tcttctttaa aattcctgat ggtgtaatta
    24781 tccaacaaga aacaggtgca tttgctgata tcttcgggcg tgatgataaa ggtaaaagtt
    24841 taagcgggat tgatattatc actaaaggag ttccaatagc gccaactatg attatttcaa
    24901 gaagtgttgg gagagcatat gaacctattg aaaacgtatc tctaaataat attgcaccag
    24961 ctcccgattg gctagtgaac ctactgctaa aaaaaccgca agaaataaag actcaatacc
    25021 gacccgtagc aaaaacaggg acagcaaaaa aattagatat gattgttcaa ggcgctggcg
    25081 aaggtagtag aaacgatcat ttaactaagt tatgcggttg gttactatgg cacggtgtag
    25141 ataatcaaac tttagcagaa ttgatttata cagcaaatgc gtacaatgaa ccaccgctaa
    25201 aagataaaga agtgaatcaa attattcgat cgatgattaa aaaagatttg agggggaaag
    25261 ctcatggctc ataagcataa attagatagt attttagact ttcccgaagc cagcgagcgt
    25321 gaagacaata tcattgaatt gaaaacctgg atgtcacgat taagatgcaa taaagacgat
    25381 cagattaaaa gtaacagtgt tgtgaatgca gaattgattt taaccaatga tagcaattta
    25441 gctggaacaa ttgcttataa cgaatttagc ggatacattc acctattaaa agattctcct
    25501 tggatcaatc gtaccgctgg agaatgggaa gacagttttg aggatgcctt aacggcatat
    25561 attgaagaaa actacaatgt agtttttgat gacaacaaaa tacacaaagc agtagtaaat
    25621 gtggctagaa agaatgtttt caacccagta aaagaacgta tcgaaaaagt taaatgggat
    25681 caacagccta gactggaaac actgtttatt gaccttttag gggtagacga caacctttac
    25741 acacgagaag taacaaaacg ttggatagtc ggatcagtcg cacgtatcta taaaccagga
    25801 ataaagtttg agatcgttcc agttttggat ggaccgcaag ggattggtaa gagtaccgtt
    25861 ccagcattac tttacacgga tgattttttc accgattcat tagattcgct aggtgaaaag
    25921 aaagatgatt atatgcagct tcaaggcaat gtaattattg aacttggaga attatcttca
    25981 atgaacaaaa ctaaaattga acagataaaa aacttcatca gtgccaagat cgataaaatt
    26041 agacctcctt atggtcggaa tgtcatagct tgggcaaggc aatgtgtatt tattggaacg
    26101 tcgaatgatg ggcagtattt gaaagatgat acaggaaacc gccgttttta tcctttgcct
    26161 tgtaagaata agccaaagat gaatccgttt aaaacaaagg atgaatattt tcttcaagtg
    26221 ttagctgaag caaaggtgct ttttgataaa ggacaacgaa tctattttag tcccgatgaa
    26281 gataaagaag tcttagaaat tgcaaaagac tatcaagagg atgccaagat ggagaatcca
    26341 attaaagaag caatcactaa atatttggaa atggaaatcc cgtataaatg ggaagaagct
    26401 ccagcgtggg cgagacgttc ttattatcag aactatcctg acagtaaatg taatgagaaa
    26461 aatttacagc atttctataa tggagctact atgcaacaag agttttattt agttgatagc
    26521 gtactcaccg ctgatatttt ggaagctgtt tttgataaac aagcaaagga tttattgaat
    26581 ggtcgatcag atgcagaaac taaaaagatt gccttgatta ttagcagtat tcctggttgg
    26641 gaacggaagc aactgccaaa aagaaataaa cgacgaggat tttacaataa gtcaaatgcc
    26701 tatgaaaata aaaatcgagc tggaaagtac aaaaagtaac gggtagtaac gggtcagtaa
    26761 cacctagccc gttactagtt tacccttact gccccaaggg atacagcaat ttggtaacgg
    26821 ggtaacacct tatttcctta aaacttttga aatagttagc taatatgctg gggaataatg
    26881 ttactggatt ttacccgtta cctgttacca aaacgctaga acccttgtcc ccgttgggat
    26941 tgagtggtaa cgggtacctg ttacgtaggt gttaccacgt gttacgaatc aaggaggaaa
    27001 gtaaatgctc aatattattt caacaaacaa agcaccgaac tttcaatata cagatgaaat
    27061 ggatcggttt ctaatgaaca cgctggcatt tagtgtggga ttggtaacag aagattattc
    27121 cacatttgat ccagaagtat taaagataat ggaagaagaa cctgattggc tgcaggagtc
    27181 agtagcgtgg tgtcaatcgc tagtagtggg atcattggta gatagtggca actatgatga
    27241 tacaggtgag ctaatggatg aatttaattg tctgcttaac ctatatgatc gagcgagaca
    27301 acgagagctt acatcgaatg aggataattt gtttttaaac atccatgata agttcttggc
    27361 tttgctacta acagatgatg aattgataac taatttattg gaggtagaat aattatgcat
    27421 atggaaagta ttagatactt cgatggtgag aaacacattg agtattcaaa cactcaagaa
    27481 gatgtagact ttattagttt tgaggaagat aaaatcacta aagttaattt taaagacgga
    27541 acgtgcttga agatagtttc gccttatatt gaatacaaat caaaatggga acaagatgat
    27601 tctgacgaac gagatcgctt tggttggtaa tctatggcag ttaaaaaaca atgtaatcat
    27661 gctggatgta aaacattgat tgattatagg cagaagtatt gtgggaagca taaagcaaag
    27721 caaacggcaa ttaagcgtga agaaagaaag caaagcgaag gtaaatattt tcaattctat
    27781 caaagtagaa catggcgaaa ggcttcatac ttgtatcggt taaatcatcc agtatgtgag
    27841 gattgcctag aagaaggctt gataaggaaa gctgatgttg tagatcacaa aattgaacta
    27901 aaagatgatt ggaatagacg gttagatgaa actaattttc gttctttatg ccatgcacac
    27961 cataattcca agacagccaa tgaaagacaa agacgagaaa agagtaccct ttgagttaag
    28021 ggggcatagt gtgaaactta ctgacaatcg atgcctactc attttggtac aaataaccgt
    28081 tgtgaaaagg cataagggta attacaaata acgattacac ttgtaatcac aagtgaaaaa
    28141 gtatataatg aaagtaggag atttattgaa aaatacaatt gttattactg ataaaacagg
    28201 gaaacagcgc accattgagt tacctcattt tggtcaagtg accattcaaa tgcagaacgg
    28261 aaaaatcatt tatatagata aattagataa agaaaaattc tgatcgaaaa acgaaggaat
    28321 gtgagcttaa ttgcttacgt tcctttttct tttgtctgaa aggaggacaa catgggacac
    28381 cctaaaatat tacacgatac aaaaggcaat atatcaagtg aagaaaaagc aatccgtgtg
    28441 gacgctagag aagaattgtt caagcagcaa ccattaataa atatcacgcc ccctgactgg
    28501 atggcagcga gcgctagaag tgaatggaat cgtatcgtac caacattaaa aaaagattat
    28561 ccattgagtg aagcagatta tggttcattg gtagcctatt gtttagcctt tgctcgaatg
    28621 aaaacagccg aagccgagat aagaaaatca ggtacgttta tcacatgcga aaacggagta
    28681 aagaaagcca atccagcggt tcgggttcaa tcacaagcta tgagtgattt gaaaaaacaa
    28741 gccacctcac taggtatgac cttagaatca cgatcaaaac tagctttgaa caaggttaaa
    28801 aatgatgaac ccgaagaccc gttcaaagag ttgatgaatt catgaatgat tacattgaga
    28861 aagtcctatc aggtaagctg attgcaccca agaaaattat ccaagcgtgt gagcgtcata
    28921 taagcgattt ggagcgttct aagtcagata gcttccctta tgtgttcgat gaagaacaag
    28981 ccaccaaagc gattaaattc attgagttgc taccatctac ggacggtaaa gcaatcaaga
    29041 tgttaggatt tcaaaaattc attctaggca gtctttatgg ctggcgtact aaagaaggga
    29101 attacaggcg attcaatcga gcgtttacca gtatgagccg taagaatggg aaaacgtata
    29161 tcgcaagtgg catggctgcc aatgcgttga ttatggaaca agaaccagca gaagcaaggc
    29221 aagtattgtt tgtaagtaac gctttgaaac aagctaaatt gggctatgat atgctgtcta
    29281 attcacttag aaacgtggtc aagtctagta agtttttaag accacaactg aaaattatga
    29341 actctaagat tcagcacttg ccctctaatt cgttcgctat ggcactggct agtgaaacca
    29401 gcacgctaga tgggtttgca ccaacaaccg caattcttga cgagtggcac gaagcaaaaa
    29461 ctcgtaaaac gtacaacgtc attaagtcag gaatgaccca acaaaagaac ggcttattgt
    29521 gtgttattag taccgctggg cttgatttaa acgttcctat gtacgaggaa tacttattgt
    29581 tagatcgtgt gctaaaaggc gaagaacaag ccgacaggta ctttatagcg atatgggaat
    29641 tggacgatcc cgaagaaatt cacgatcaag agaaatggat caaagccaat ccgatttttg
    29701 aaagtgaaga aatcaaaaaa gtaatgattc caaccattca agatgatgtg aaccttgctt
    29761 tgaaacaaaa taaccttaat tctgtattgg tgaaaaactt caatttatgg agacaagcga
    29821 gtgaggacag ctatatgatt gctgaagact ggcaggcaac cgaagtagaa ccacaagata
    29881 ttacaggcaa gcccgtttat atcggagtgg atttatctaa aacagatgat ttaactagcg
    29941 tttcatggat cgtaccgcta gataacggcg aactttattg tgattcacat agctttgtag
    30001 ccaccaaata tgggcttcaa gacaaagaaa agcgcgacgg tttgccttat cgagaactag
    30061 aaaaagctgg tgagtgttcc attactcaat tagaaagtgg aatcgtggac tatgaccaag
    30121 tatttcagtt tattcaagat ttgattcaag aaaatgattt ggaatgtatg gggatttgtt
    30181 atgacccgta taacgctaat tcgcttatca gtaaagctga aaaagccaac tacccaatgt
    30241 tagaagtaag acaaggaacg attactctaa acgttccgac ccgaactttt agagaacaag
    30301 tttatgaagg caacgttatt cacaataaaa atacgattct cacccatgca gtgaacaacg
    30361 ctattttaaa aacggataac aacggcattc agattaataa atcaaagaac agtaacaaaa
    30421 ttgatccaat agctgcatta atcaatgcct atgtgtttgc aatggattac ttcaccacaa
    30481 cggaaggagc gaaagcagac aatgaatttt atacaagtga agaattttct ttctaattac
    30541 attcataccg ttcttttact tcttggattg gtgtgtgtgt tggttgctat caccttacta
    30601 acaaatgtct actatggctt gttagcgctg ggcatagtgc ttattggggt agcggtcatg
    30661 ctaaatacag aacagaaggg aggttaaaag atggcatttt ttaaagcgag acaaaataca
    30721 acgggagatc ctttcctaca acatgtggta tcaatccaat cggatgatta caccaccagc
    30781 tttacaagcg ttcgtgcatt aagaaatagt gatgtgtttg cagccgttcg aattattgct
    30841 agtgatattg cttcaagtcc gattcaattg gtcaaaaaca atatgccaca agctgataat
    30901 gaactggtga agttactaaa cgagaaacct aattcagaaa tggatggttg gcatttaaag
    30961 tttgctttgg cggtcaatat gttgctaaac ggtaatagct ttgcagagat taaacgcaac
    31021 ggtgaaaagg tagaagaaat tcacttatta cctaactcaa gtgtaacggt tactcaatta
    31081 gataatggta cgttgtctta tcagattggt gataaaaaaa gacgtgtgaa gtctagcgat
    31141 attttgcact tcaaatattt cacccaagat ggtttaacag gattaccacc actttatgcg
    31201 ttacgtgatg aactgaaaat tcaacaagct ggcaaccgca cattgcacaa tttctttact
    31261 cgtggtgtca gtgggtcagg tattttgaag gttcataagt cagatttaga cggatcagca
    31321 aagaacgcaa ttcgtgaaaa gtttgaagaa gccaacggtt caagtagtgg agataatgct
    31381 cttagaacga tcattcttga tgaaacaatg gactacaaaa cattagaaat aaacaccgat
    31441 gttttgaagc ttatcaattc caatgattgg aacacaaaac aaattgccaa ggcgtttggt
    31501 gtaccgattg agcgtttagg cgttgaaaat gaacattcta gcaccgttca aagtaatctc
    31561 cagtatatcc aaagtacgct gattcattac tttaatgtgt ttgtgagtga attagatacg
    31621 aaacttgaaa ccaatatccg ctttaattcc gatcagttac tagagactga tcctgaaaca
    31681 aaagtaaaaa atgtattgga tcaggtcaaa gggtcacttc tcacgattaa tgaggggcgg
    31741 tcgaaaatgg ggctaccccc catggatggt ggcgatcgtt tactagcaag tttgaacttt
    31801 acgtatttag atacgttgga gaaatatcaa ttaaaagaac aggaaggagt tacaccagtt
    31861 gaataatgaa gaagaaaagg aaaaacggct gacagaagaa gctgagctaa cagccgattc
    31921 tcccaaagta gagaaagaaa atgaaaaaca accaacagac ggcaaaacta tttcaggcta
    31981 tgcgttgaaa ttcgggcaac cgtcaaaaga tttaggcggc tttgtagaag tgattacacc
    32041 cgaagcatta aaagaggtgg atttatcaaa tgtgttctta ttatatggac acgattattc
    32101 aaagccacta gctagtgtca aagcaggtac gttgaaattg aatgtcgatg atacaggatt
    32161 acattttgaa gcagagctaa ccgacacgac ctattcaaat gatgtgtatg agaatatctc
    32221 aaaaggggtt gttgattcta tgtcctttgg gttcgtgctt ggattagatt cattcgacaa
    32281 aaaagaagat ggcacaattg aacgatcaat agataaaatc aaagcactta atgaaattag
    32341 tgtcgtgacc gttcccgctt atgattcatc aaatgtccaa gtaaataagc gttcttacga
    32401 atcgtttatg agtaacaacc aagcaaaaca aacaaacaat agcttagaat ccacttctaa
    32461 agcacaaaag gagagtaata acatggaaaa aactttaatc gataacgaaa aaacagaatt
    32521 gcgtgggtat gaagaatata tccgttcaca aggcgaagtg cgtgatggag tcactactgt
    32581 aaatgcagcg gcagttgttc ccgaagaagt aatcggtgaa gtctttgatt tgaaacgttc
    32641 aaattataac ttagctcaat atgcaacagt aaaaacagta tcaaatggac aaggtaaata
    32701 tccagtagca actaaccaac aagcagtgtt agcaacaaaa gctgaacttg ctgaaattgg
    32761 tgatattgac gctgaaatgt ttacttcagt tgattataaa gtagaaactc gtgctggtaa
    32821 gattgcctta tcaaatgagg ttgtggaaga ttcagcagtg aatattgtac aagaggtcaa
    32881 agatcagtta gcgaaattgg tagaaaacac tgacaataag catatcatgg atttattaaa
    32941 aacattcact aagaaaacgg ctgctacgtt ggacgatttg aaacaactat acaatgtggc
    33001 attagaccca gcattaaata aaatggtaat tctaaaccaa agcggatatt accacctaga
    33061 tacattgaaa gattcagatg gacgttacat tttacaaccc gatgtgacag cacctagtgg
    33121 taaatcatta ttcggtatgc cagtagtatt gattgcagat acattgtttg ccaatcctaa
    33181 agctggaaca ttccctatga ttatggggga tattgcacaa tctatctttg ttgctcgtag
    33241 aaatcaagta acgactcaat gggaaaaatt cgattactac tcacaaggac ttgcagtgat
    33301 cgttcgcaac gattataaga aaattgatca aaatgcttca gtgtatattg agtttacgcc
    33361 agttgtaaca ccaaaagtat agaaaaatat tgggcggcgg tttatcccac tgcctttttt
    33421 tcattaggag agataaaatg gtaattttgg atagcataaa aaaaagtatg cggatcgatc
    33481 acactattga tgatgacttt attcaacaat tgattgatac agcaggcgaa tatataaaaa
    33541 gtgctattga tagtagcgca acggataaag atatggataa ttatcagcaa tttgatttgg
    33601 cggtgtcatt acttactcaa cattggtatt tgaaccgtca agaagccagc agcgaacgga
    33661 taccagtaac ggtacaagca ttagtacaac aaatgagagg tgcttattat gccaatcatt
    33721 aagaatgtaa atgaattgac tgagagagtc aagtttaaaa agacaaaacg ggtaaaagat
    33781 gaagatgggc agatggtgga tagtgaagaa actgtatttg aatgttgggc taatgtgcgt
    33841 tcacaaatgc taaaagacgt gcttgctagt gtaggtacca ttcttgaagg aacgttgacg
    33901 tttattattc gatacgatca agattatgaa ctaacaaacg atatgaaagt agcttggaaa
    33961 aacaagagtt ataaaattat ttcaatcaat gaaggaacgg cgtttaaaga ttatacaacg
    34021 atcatagcta aacagatttc ttagaatgat tacacttgta aacgttgtgg gtatttagta
    34081 taattaaggt agtaaatgaa gggttagctg cctgaatttt gcaagactta gctagtcgaa
    34141 atctattgtt ggactgaaaa ttgtaggtgt ggttgcaaac atgctggact aagaaagatg
    34201 atagatgatg aacgttcaat tttaatacag gcatgctagg actgattgga tggttttggc
    34261 aagctgattg tgtagaaatc aaagaacacg tctgttgtgg acgtgttttt tttgttataa
    34321 ttcaaaagag gtgatttaat ggacaaagca gagtttacaa atttttattg gaagtattat
    34381 ctacatttag aaaatgagtt tattaatacc acagattttg tgatgctcga tgagaataat
    34441 ttcaaaacat tctctattga atatcaaaaa ctactactag cgattggttc ggagtgtgag
    34501 attattttca aagaactttg cggatttgat agcagtagca ataaaagcat aactgatttt
    34561 aaagctgtta ttaaatctag cgaattaatg tgtttggata atggtgttag ggttatgaat
    34621 tctttaacat tgacttcact aaaacctttt ggagatgggt ggcctgaaga tacaccagat
    34681 tggtggaaaa tatataacag agtaaaacat ggtcgttctt caaattataa ggaagcaaat
    34741 ttggaaaatg tgttgtatgc tttagcaagt ctatatttat tagaggaata tttgcataag
    34801 aaagtaatac tagaaggtga agtagacttt ataagtccag agtcaaatct atttacgtta
    34861 tcttgggaaa gaaaacattc gtcgatgcaa aaagtgacgt ttgaaaaagt ggattcaaat
    34921 tatgtagctc cactcattga ttttaaagaa caagaagaaa tttaaaaacc cccacggctt
    34981 attgaagttt ttgtatgcca tattgtatgc catttggttt aaatcgcttg aaaaatagtg
    35041 atagataact ctaattcatt tagtcataaa cgctgttttg ataaccttta tagttctttg
    35101 atatgggttt ctcattcatg gcggaagaag aagaatagaa caaaagaatg aattaataag
    35161 atataaaaaa agggattgtg acaaacgtct tgtcacaatc cctttttcca aataaacgat
    35221 gttcaatcag ctgcccctcg gcattcgctc gaaaaacggc gaaatatgaa gaactatttt
    35281 gccatttgtt tctctaataa tcaggtcaaa acgttgactt cacagtctct tccttaaacg
    35341 gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat gagaagctgt
    35401 tttttgaaat tgttccttgt gactcggagc tgaacggcag gctcacgacc tctttcttaa
    35461 acggtgttca aaagcttgca tctgcggtaa taagttcaac caaacgaaaa ttatgaggag
    35521 ctatttttgt ttggctgttc ttattacttg atgcaggaca gctttttcac aacctctttt
    35581 cgtttagcac taaatttcct taaaaagtag aaaagctttc gaagcctcgt ttgtttcttt
    35641 tactgtataa taaaagaaaa gagtaacaat cgctaaaaga tataaacaag agaaaggaaa
    35701 tacaagatga ttggtctgat ttattttgtg gtgatcgttc tggcgaacac agttggcgct
    35761 atttccggga tgggtggagg cgtgttgatc aaaccgattc ttgatcttat cggcgcccat
    35821 tctgttgcag ggatttcttt ttactcaaca gttgcggtat tcacgatgtc cattgtttcg
    35881 actgtgcgac aagtatcaag cgggaaatca ctgaattggc agattgtcgg ttgggtatct
    35941 agtggagctg ttgttggagg agtagtcggc aacattgtat tcgaagtttt tttacagtta
    36001 tttgaaaacg agaagcatgt gcagctgatc caaatttttt tgacggtatt gaccttggtt
    36061 tttgcgttct tctacaccaa gcatcatcag ccaaaatttc atttgacgtc atggacttgg
    36121 taccttatat gtgggggggg ttctgggctt tttagctagt tttttaggta ttggtggtgg
    36181 accagtcaat gtttctttgt tgatgctgat gtttgcattg ccaataaaag aagcaacact
    36241 atattctcta tctacgattt tcttttctca actggcaaaa ttggtaacga ttgctttaac
    36301 aagtagcttt atgcgctttg atttatctat gttgttttat gttatccccg ctgctgttat
    36361 tggaggtttg tggggagcaa gatttagcag ggttttgtct ccaaaaaaag tgacctttat
    36421 ttttcaagta attgtcctcg tggttctttt ggtcaattgt tacaatgcct ttgtcatctt
    36481 acaaacatta ggagaatcta gactaacgca agtcaaaatc actgaaacat attgttctaa
    36541 atgaaaaaaa gagtatacta tgataaaaaa attcatttta aaaaatcaga aattggctgg
    36601 tgatttggat gttacgggaa atgcgtttag aagatgcaga agcactacgt gaaatcaatg
    36661 cggatcaatt agggtatgat ataccattaa ccgttacggt gagacaaatg aagaaactgc
    36721 tgaaggagcc agagaaaaat tttttcttgg tttatgaaga tcctacttct aaaaaagcag
    36781 ctggctatgt acaagcggag tcctatgaat cgatttttag cgatccaatg ttcaatatta
    36841 tggcacttgc tgtgtctaaa tatgctgaaa aaagaggcat cggaaaggct ttgatgactg
    36901 gcgtagaaga agaagcgaaa aaacgaggaa taacgacaat aaggcttaat tctgcagaat
    36961 acagagtaga agcacaccaa ttttatgaac acatcggtta tcattccgat aaaatgcaaa
    37021 aaagattttt gaaaatcctg taaatcttta tcaaaaaaat acccgatcac caagccgata
    37081 cttgatgatc aggtattttt gtttttttga ctaagaaagt aattgcatca agaaaccaga
    37141 gatgatcaaa acgatggcac caccaagtcg attgcccatt tgagcaaaag caataagttc
    37201 catccgatta gctgcagata agacggctac atttcctgtt ccgcccatcg agttgttgca
    37261 taagccagca gtaatagttg attcaattgg atataaacca aacaaacgac cgacaaatcc
    37321 tgaaacaact gaaatcgcga taacacttgt cagacataag acaacaaatt gccatgtcaa
    37381 agcagaagct aatacattca gattcagcaa cgcaataccg ataccggcaa gaacagctgc
    37441 tgtcaagttt ttgacaatca agttattgaa catgatagct gcatcttcat aatactctgg
    37501 taataggttg gcgattttac agatgacaac gataataatc ataaatgcgt aagcatggac
    37561 tttaggaaca aaatagttac caatttgtcc taagatgaag aaagtcaatg ataccatcaa
    37621 accaacacct aactgtggaa tggaaggttt cacagttcga ggttttccat cgccaagatc
    37681 gcctttttcc attaatttac cattgccgtt gaattttggc attgattgtc cagcacgagc
    37741 aactaatgct gcaccgatga tagctaagac atttgtcatt gctgtcgcag gaatcaggcg
    37801 ggaaatgata gaagaagcat ccgtacctaa aacatttgca taaatcgttg ataaaggaac
    37861 ggctccggct ccaacaccac cagccatcgc aggtaatgag atgtataaaa cggaatttgc
    37921 aaaaccattt ccgataagca tgcccacgag tcctacggca aaaaaggaga cgaccattga
    37981 aataagtgca acgggaataa aacgaacaga agctttcatc aatagattac ggttcatacc
    38041 aaggatgcta ccagtaatca aggcagcaat ataaaagtcc caaaagccca tattgctgac
    38101 aaagttttct gtggatttca ctacatattc aggtaagatc ccaaatgtag caatcgcagc
    38161 agaagcgaag atcgcaaaaa cggaaccacc acccaaataa cttttgacga tagggatttt
    38221 tgtcccgata aaatgaaata aattaccgaa aataaccaaa actgcgattg gtccaatcat
    38281 attcgtcggt aatttcccta aagccattgc aatgatcagg acaaggacca tgatcaaata
    38341 aagtggcaaa cttacgccgg tgatttttgt ggaccaaaaa ccttcttttt tcttttcctc
    38401 aactgcagtt gcagttgttg ttttttgtgc catttttaca gatcctttct tattctgtat
    38461 catatgaaaa aagccaaaga aaagcgacaa aagagcagga gttggctggc cgctgttttg
    38521 ccgcagtcgc ttttttcttt ttagacgtca tacaaagttt ctgtatgttc ttttactata
    38581 acgatcttaa tcttctaaag atttatattc aggaacccat ttagcagatt caactgcttc
    38641 tttgatatcc gtgatttctt cacgattcaa gttttgtgcg acaactgatt ttgcgacagt
    38701 ttcagcaatc gtttgagaaa attcagtgat ttttgctact ggaggcaaga tagctgctcc
    38761 tggttttgtt acatcaacga ttccgcctaa tgctcgacta gcttgagaaa tgatttcagc
    38821 atttactcgt gtagctgttg aagcaatcaa accaagtcct aaacctgggt acatcaaagc
    38881 attatttgct tgaccgattt ggtaagttac accattatat tcaacatcag cagcagggat
    38941 acctgttcca actaatgctt ttccgtccgt ccattctatt aaatcttttg cttttgcttc
    39001 tgccaatttt gttggattag acaaaggcat gatgatcgga cgtggtgtat gagcagccat
    39061 ttctttcacg atttcttcag tgaatgctcc aggttgggta gaagtaccaa tcatgattgt
    39121 cggatggatc gcttttacaa ctgcttctaa gtttgtcaat tcatcagcat tagtgaaatc
    39181 tgagcgtttg cgagcgaatg ggatttgacc aggagtcaat ccttctgtat cttcaaacaa
    39241 taaaccttgt ttatctactt gatagaaatg ttggcgtgct tcttcttcag gtacaccttg
    39301 acggatcatc tcatctaaaa ggatgtttgc gatacccaca ccagcagtac cagcaccaaa
    39361 tgtcaaaatt atttgatctt tcaattgttc accggatata ttcaatccgc ctaatacacc
    39421 tgctaggaca acaattcctg taccttggat atcgtcgttg aaagtagtga tttgatcttc
    39481 gtatttttct aagatcgctg cagcatttcc tcgtccaaaa tcttcccaat gcaataacaa
    39541 ttctgggaat aattcggtag ctgattgaac gaattgatcg atgaattcat agtaagtttc
    39601 gccttctaca cgagcatgac gattgcctaa gtataaggga ttattcaata attcttcatt
    39661 attagtacca gcgtcgatcg atacaggcaa aacttgtgct ggattaatac cagcagcagc
    39721 agtatagacc atcaatttgc cgatagcgat gtcaacaccg ttcacacccc agtcgcccat
    39781 acctaagatt ccttctgcat cagtcacaac aatcaaacga atgtctcgtc catctgccgc
    39841 gttcttcaaa cttgctttga tgttttctgg ttcgtcgatt gaaagaaatg cagcatcttg
    39901 cggtttcaag aaaatttcgt tgtattgttc gattgaatcc gcaacgacag gatcataaac
    39961 gacaggcatg aattcaacta aatgttcgcc catcaattta taaaacaatg tccgattcgt
    40021 attgaataga ttcattaaga agatacgttt ttccaaatct gtttgtttgc ttaagtattg
    40081 accataagct tgaacagatt gttgttccag tgtttggaca gtacttggaa gcataccagt
    40141 gattccatat tttgcccgtt cttcttttgt aaaagctgtt cctttattta gaaaaggatt
    40201 atttaataag tttaaccctg taagcatgaa tgattcctcc taagttttaa tacaaacgaa
    40261 gtatagaagt cagatgatga tatagtcaaa aagagcaggt atgataaatt ttatttatat
    40321 gtaatatagc caaaagaaat caaaatagca gtatttgttc tttttatatc gacaatcctt
    40381 gcttgaatac tatgcgtatc tcttatatgc tagagaaaga aaagtagaag aataagggat
    40441 agatggaatg gataaatagg atttctgagg aaaaaagcac atgatagcgt tgataggagt
    40501 cacctatgtc aggtgataaa aatacataag tagaaaatta agaggaggaa gagaaaatga
    40561 aagaagttca attgattaga aaaagcgaac tatcagaagg cggttgcaat gcatgtggcg
    40621 tagtagaagc gacaagctat acattaaaat tagattccaa tcaagcaata atctctgaac
    40681 tgacagtagg cggtcttgtg gacagtctgg cgcttgctga aggttttact ggagaagata
    40741 tttatgagat gttttcagaa gtccgtcagt taaaaaaagg agaaaaatgc atagaggttc
    40801 atcatgagag cccgaatgtg aggttcaaac gtggtgataa tgagatgatc ttcaagaatc
    40861 atgtgtctga tcacactgaa ctatatgaaa tcgtgaatca aatactgtct gggatttttg
    40921 aattaggacc ttatgagttc aaggaagaaa acggtaatcc aaaattaaat gaagaatggc
    40981 aagaaacgat tgaaacacaa agaaacaatc cacacttatt tcaatagtct tccacagtat
    41041 ttcgtaaaaa tgttgatgaa aaagaaacac cgtgaatcag aggtcgtgaa aaacctgccc
    41101 tgcatcaagt aataagaaca gccaaacaaa aatagctcct cctatttttc gtttggttgg
    41161 gcttattacc gcagatgcaa gtttttgaac accgtttaag gaagagactg tgaagtcaac
    41221 gttctgacct gagtattaga gagacaaatg gcaaaatagt tcctcatatt ttgccatttt
    41281 ttgagctaat accgagggtc agctgattga acaccgtttt atcgagaggt tgtgaaaaag
    41341 tcgcttagtt tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata
    41401 aatttgactt aataccgaga aaatggcttt tgaacaccgt ttattcaaaa aaagggactt
    41461 tgacactact tttgtcaaag tcccatcggt tttttatcta tttttattac aatcatttct
    41521 tccagagtag tgacatctgg aatggctgaa atgtaaacag attatttgcc tgtatcaatg
    41581 tcgaagagta atataaaaag tgtaaacgct atcatattgt tcatcattca aattttatag
    41641 agagaaggca ttgagatgga aaaaacatat caagcaggta caaatgaagg aatagtagat
    41701 tttatcaata tggaagattt agaaatcgcg gcttcacaag tgattccagc tggtggttat
    41761 ggttacatca gcagtggtgc tggcgactta tttacttatc aagaaaatga acgggcattc
    41821 aatcatcgtt tgattattcc tcatgtatta agagatgtag aattacccga tacaactaca
    41881 cattttgacg aagaaatgct gactgcacca atcatcatgg caccagttgc tgctcatgga
    41941 ttagctcatg tgaaggcgga gaaagcttct gcaaaaggtg tagcagattt tgggacgatc
    42001 tatacagcaa gttcttacgc ttcttgtact ttagaagaga taagagaagc aggcggggag
    42061 aaagcaccgc aatggtttca attttatatg agcaaagata atggaatcaa tttggatatt
    42121 cttgaagtgg ccaagcgtaa tggagcaaaa gcaatcgtat tgacagcgga tgcaacagtt
    42181 ggcggaaacc gtgaaacaga ccgcagaaac gggtttacct tcccgctgcc aatgccgatc
    42241 gttcaggctt atcaatcagg agtaggccaa acgatggatg ctgtatataa atcttccaaa
    42301 caaaaactta gtccaaaaga tgtagaattt atcgctgctc attctgattt gccagtctac
    42361 gtgaaaggtg ttcaatcaga agaagatgtc tatcgatcat tagaatctgg tgctggtgga
    42421 atttgggtat ctaaccatgg tggccgtcaa ttagatgggg ggcctgctgc gtttgattcg
    42481 ttgcaatatg tggcagaagc agtagataaa cgtgtaccaa tcgtgtttga cagcggtgta
    42541 cgacgtggac aacatgtttt caaagcaatc gcatcaggtg ccgatcttgt tgctattggc
    42601 agacccgtta tttatggatt gtctttagga ggaagtacag gagtccatca agtgtttgat
    42661 ttctttaaaa cagaattgga aatggtcatg caattagctg gaacacaaac agtagaagat
    42721 atcaaaaaaa taaaattgcg tgagaatcgt tttatttaag aaataaatga cgaaaaaaat
    42781 aggagtgcgg cagatgatgc cgtactccta tttttatagt tcaaggatgt cactaataga
    42841 ataatttgaa acgaaaaaat aaaattgaaa tattttttca tacttaataa aaaaggaaga
    42901 atattcatgt aaacgatttt attgtttttt tctcttttat acaaaaaggg tcataatttc
    42961 aagtaagcgg atgaattcat gaggattttt tgcatactgt ctctactata cttaggtcac
    43021 taagaaaaag gagtgattta ttatgaaaaa gaacatgatt gggacattat tactttcaac
    43081 acttcttcta ggcggcttgg caacaccagc ttttgctgag ggtcaagcga cttcaaaagg
    43141 agatattacc tttactgaac caacaaatac cgttgagcct cttaacccta ctgatccttc
    43201 aaaaccagta gagccagcag atccggaaaa tccagcaact ggccagacag gttctttaac
    43261 attggatgta gttcctgaat tgccatttgg tacacacgag attgaaagcg gaacaaaaac
    43321 gtatcaagta gacgcttcaa aaaacgatac accttatctc caagtatcag atcgtcgagg
    43381 tgtaggtgca gatggccaag cacaagggtg gaacgtgaca gtttcggttt cagattttgt
    43441 aaacggttca caagttttgc aaggcgctga attagatttt ggaacatcca ctgttaaaag
    43501 tacgtcagat aacgaatcca ctggaccaac tagtcaaact gtaactgggt tgagtaaagc
    43561 aagtgcagcg acaccaatat ttacagcagc aaaagatcaa ggtctgggaa catggctttc
    43621 tgtttatgat ccagcaaata tcacactgaa agtgccgaaa gcagcagctg gaacattcac
    43681 ggctgatttg acttggaacc tcgtggctgg cccagtagca tagagtatga aataaattca
    43741 acaaactgcg gtgaaaatac tataggtgaa ggatttttta ccgcagttgt tgttgaaagg
    43801 atgtggtgga caatgaatca aagtaaacga ctgtttgttt cgtttttttc tattttaagt
    43861 ctatttttca tttttccgtc aatcagccaa gcaaaggatt cagcaggaga ctttggaatc
    43921 aaaccggtat ttccagagaa ccaaatagat aaagcaatcg gttattttga tttattagtg
    43981 gcaccggaac aaaatcagac actagaagta attatcagca attcttcaga tgaagaacga
    44041 acatttgagg tctctgtcaa tccggcggta acgagtgatg gtggaacgat cgattatagt
    44101 caaaaaaacc caacgttaga tgagacattg ccgtttgatg tccgtgacgt tttgctcatt
    44161 gcgaaaaagg aaatcaatgt atcagcacat gcagaaacaa ctatacctat agaagtgaaa
    44221 atcccagcaa aaagctttaa gggacgtgta ttagcgggta ttcatgtttc acctaaagaa
    44281 gaagctgaaa cagaaaatgc tacagaagga gcacaaatca aaaatcgtat tgcttataat
    44341 ctcgcagtcg ttttacaaga aagtcaagag acgatagaac cggatctgaa acttttatca
    44401 ggagatttgg acgaggtcaa cgcaaagcca actgttcagc ttcgtttcca aaatcctcag
    44461 cctaggatta tcagcaattt gatatttacg agcaagatct tttatgaaaa tcagctttat
    44521 attgaaaata cgtctaatga atttttagtt gcaccaaatt cgaattttca cttgaatctt
    44581 gatttagctg gtgataaagc aaaagccggc gattaccgcg cagaaatcat agcaaaatca
    44641 ggcgacagta atgaatggcg atttacacaa aactttacga tcaaaaaaga aaaagcacaa
    44701 aaagtaaatg aaaattccgt ttttgcagta caagaacaat ctttcccatg gctttatgca
    44761 ggattggttg ctgcagttct agtgttatgg ttgattttgc tgtttttgtg ggtccacaag
    44821 aaaaagaaaa aaggagaaac aacatgatga ggtgatttcg ttgaaaacat cgatcttatt
    44881 gggagggatt attgcaagtt tgctgttctt cagctggcaa gagccagtcc aagcagatac
    44941 caaaagttca ggtacgatta cattttatga tctaagtcca gttccgcatc caagtggttc
    45001 agtcaatggc gcatcaaaac agcagacaca gctaccgatt tataaagaat ctaatcaaca
    45061 tggcgtattc ccggagacga atgaagaaaa gatccgtttt ctttatttga tcattggtat
    45121 agaattatgg cttcttgcgt ggttgttgtt atggagaaga aaggaaaagg aggatgaaca
    45181 tgttgctaca aaataaattt tcattttttc gctccttctt ttttacttcg ctttttgttt
    45241 taagtatatt tatcttttca ccttcggcag aagctgttgg agcaacgcct cctgccattt
    45301 cttatgatcc atacacgtat gaaaatatcg tacctccaaa tggtggacgt agtgcagtca
    45361 atggcgggaa gcttgtccaa ctaactgggg ctaaccaatt gcctaaattg actgctactt
    45421 atttgaacga tggttcaaat gatccttgga aaggtggcac ggtccgtttt cattgggaaa
    45481 gccatgtgaa actaacaaat gtacttgatt tggtgaatat cactgcacaa ggatttgcat
    45541 ttgtggcgat catcaatttg ccggaacatg tatcaagcag tgatgtatta aaagcaattg
    45601 actggaacaa cgcctacttg tatattgccg gtgcccccat caaggttact agcggtagtt
    45661 tattatcagc aggaagccat accttgcgtt ttgggatggg gtcgtgggat acaaatactc
    45721 tattggcaga tattattgct attattacgc gaggcgaatt caacgtggac gatatcccgc
    45781 ttcaatttga tgttacagct aatgtcgcga agatgacaga aaacggagat aaatatgata
    45841 cgagtccaaa caaaattttg accaagggta aattacaacc ttctatgtct aaaaaggccg
    45901 ttttttctgt tgatttttat gattcgaata atattatcca agatcgtatg ttcaattcga
    45961 ttttagctcc agctgcaggt agattttatc ctaaattaac tggcggaaac ttgaatccag
    46021 gagcatatgc attttctgca agtgcagaga taaatacgtg gaatagttac atctcaacaa
    46081 gtgattcaac aggaaaatat aatacatttg ctgataccac agaatacgtg gatggaaata
    46141 accagaacct tccaggctct accaatagtc ggacattgac gatggggctg actgaaggac
    46201 gttttgatca gttgccattt agtcgctttg atcgcgtagt caactatttt acaggaaaaa
    46261 acgttacaca aggagcaata ctgactcata ctccagcaag cacaagtgga ttgaatcaga
    46321 cagccaatat cgtgtacagt gggaaagatg cgcaaggcgg attgctttct cctgttgctt
    46381 taaaggtatt ggagcagtac aagctagacg gaacggtttt accaacaaac ttaacagccg
    46441 atagtcagtg gggaaagctc ctttcttctg catcgtacca agtcacggcc aattggtcag
    46501 caactgaact aaaaaagggt tcgatccatt acaggcttta ttcgaaagga acccaaaaat
    46561 tagcgacagg atggacagat caacttttcc aaacgatcca atcaaataac gggggtgtaa
    46621 atacagctac ttctacacta cctgcattgg cttcagggca atattatttt gattatcgct
    46681 tggtggacga tgtacttact aacatgtatc cgtcttttgc gtacaaatgg cagtctgaac
    46741 aagctggaat caccactctt cctcaaataa cagtggctaa ttttccatct gtgagtgcag
    46801 atagtcagct aaaaaacctt agcagacaac ctgagacagg agatcccctg tctgctctat
    46861 caggagatac gattcaagaa aatgtgacat tcacgttaac aaaatctggg gatgcgataa
    46921 ccgacaaaaa aatcacgatc tcacttcctg aaaatactac ttatatcaat ggttccttaa
    46981 aattaaatgg tacaactatc gcagataccg gcattcaaca aggagtttct gtcccagcag
    47041 atctattgag caaaatagga gataccattc atcttactta caactatcaa ttaaatactg
    47101 tagatacttc tgtacaatcc gtcagcatac tgacaaaggc agctgtactt tccagcaata
    47161 ttacattagc agatggtgct aagcttccta acccagttgt ccaaacatct gctaaaacaa
    47221 ttcttgtccc caaacaagaa ttaacattag ttaatgtacc agatgatttt acatttggta
    47281 acgatctccc caaaccgttg aagacaagtt attatgaagc aaaaggcgat ttttcttttg
    47341 atgtgcggga tactcggctt ccaagcacgt ctccttggca actgacaggg acattgactt
    47401 ctttatttaa gaatgatcaa ggtcaagaat taagcggaac aaaattatac ttcaatcatt
    47461 ctggatcaaa acaattgatt cagcaaggtc aaaacacgtt gatttatgag agtgatggaa
    47521 cagctaaagg agaggttctc gttgactttc ccgataccga tggtttactc ttagaggtaa
    47581 atagcagtac gaatgctcaa cctggcgcaa cgtatcaagg catggtcaca tgggaactga
    47641 cagctgggcc aaccagctaa gtgattagaa tttgtatgga tctgtgataa ctgtcacaga
    47701 tcctcttttt caaggatgag aaggaaactt ctgctgttaa aatcagaaat gcttggagga
    47761 gtggacttgg aacttttcag tttgcttgaa aaaaatgaac aacggcaaat caaacttttc
    47821 caacttttat tagaggaaaa aggagagatt tccgttaata acgtacttac ccgcttatca
    47881 gttgatcggg ctaccttgaa agaagatctg ttttatttac aagctaactt ggaaaatatc
    47941 aaacaattgg aaattgttat ccaagaaggg aatattttat taatcagaca tggaaatata
    48001 gcagcagtcg atgtttatta tcattgctac ttgcgctatt ctacaaaata tcagatactt
    48061 ctttatctgt tggaaaatgg ctcatttgat cggcagaaac ttgtcatgga acttaatatc
    48121 agttcggcta ctttgtctcg cagagtgaag gaattaaatg attctttaaa tgagtttcat
    48181 ctgaaaataa aaagcgggcg gctgaccggt ccagaaagtc aaatttgtta tttttatttc
    48241 caattatttt ggtttggacg tccttatctt gaaaacaaaa aagaatacag tgatttatca
    48301 ggaaacactt ttttagatct gctgcaaaaa gagtttagtt ttactattac agaagaagga
    48361 cgattgaaat ttgaaatatg gctttccatt atgaagaagc gaatgcgctg tacgaaaaaa
    48421 tccaaaccag attatagcaa tcttcctgtt ggattgtttc aaacgacaca atttttattg
    48481 gacctccata catttttgac ccgttacttc tttcaatatg cctttccttg gaatcaaaat
    48541 gaaacgttgg ttttttatct tttcatgatc agtaacttta cattagatac acataactcg
    48601 catgtccagg agtttttgat aagcgaaaaa tacaaagacg acgtagtagc tcaattgaat
    48661 cgaacgttta aacaatcgat agaagaatat ttctcttttt atgtttttcc agaagagatt
    48721 tcgcaaaaga ttgcgttgac agtgatgcaa aatcacgctc attttgccta ttttagagga
    48781 tggatgaata tttttggcca agaaggatta aaacagcggt taactgaagt agaagataaa
    48841 caattcctgg ttttatgtga aagattggtc agacaaacat ttgctattgt tgattttact
    48901 gaagtagacg aggaaaatgc ccgctttgaa ttatttgctc gctatgcatc tattttgcgg
    48961 acgctgatca agcagttaga attacgtctg caaattgctt atgatcttcc ttatgaaagg
    49021 ctaatggcgg atatcgtgaa agaaatcatc caggaacaat tgctgaatac gatcaaatat
    49081 gatttagtcg aatacgagaa agaaaagcag tatgatatca ttttgactag ccaattgaaa
    49141 gagtacccgt cacagaagtc cgctaaagtt tttgtattca ctagcaacga atataattat
    49201 gatttcccct atttgaacca atttttaaaa gaatgttatt tagaaaaatt gaatttaagg
    49261 atgaataaaa catgaaaatc gtgatcattg gtgcttccca tgcaggcatc acagctgccc
    49321 taaatctaag aaaacttcaa ccgaaagcag aagttttact gatcgatgaa gatcataaag
    49381 atggactagg ctatgtttca aatggaatca acctttattt aaaaggaaag atacgtagtt
    49441 tagctgaagt tgcccataac atgcggactc ttcaagaaag tggggcaaaa ctgatcaccg
    49501 aatggagagt aactgaactt gatccagaca aacatcagct catcctcgca tccaaagaag
    49561 gaaaaaacga gaccataacc tatgataaat taatcgtagc aacaggttcc tctcctgtca
    49621 ccttgtataa acaaattgaa gctgaaaatg tctacaccta taaaaatcta gtgcaatcta
    49681 agcaagtact tgccgcttta aaagaagcaa aagaagtagt gatcttcggt gctggttata
    49741 ttggattgga attagcagat gctttgagaa ataaaggata cattattcat ctagttgatt
    49801 atatgccgaa tgttttatca agatatttcg ataaggatat gatcaacagt tttcaaaatc
    49861 agctgcaaac taagcaaatc aatttttatc caaatgaatt cttgatcgat tggaaaaaat
    49921 cagaagagaa agtagtatcc gtacaacttc tatctcaagc aataaaggca gatatggtca
    49981 ttttttctgc ccaaactcgt cctaatacga cattgttaaa agaaaaagtg gctttgtatg
    50041 aggatgagac tgtgatagtc aatgaatatc tgcagacaag tgatccggac atctatgcga
    50101 ttggagatat cgtcccagtc agttttgaca aaaataaacg gcatctcttt ttacctttag
    50161 ttactcgagc tgtacatatg gcaagagcag tagcgctaac tttgagtggt cagccaaccg
    50221 cttacgacct cagacaaaag ataacagcag cagtcattat agactacttt ttaggaactg
    50281 tagggctgac agaagatgaa gcgccattct tggaacaaaa taccggttcg tgttcaggag
    50341 aatttgatct atttccacaa tacgatgaag aaaacaaaac agtaaatgca aagctgatct
    50401 accatccgga tacattagaa ataattggcg gacagctgat aagccaagaa ttcttattat
    50461 cagatttgaa cctgcttgcg gatatcgtga aacacaaaac tacgattcca cagctagcag
    50521 ttgaggattt tggatttctg tctgaacaca cctctcgttt tcactacctc aatgagttag
    50581 cttttaaagt actagctaag agagcaaata gcaatagagt agataaaaga ctgtgagaaa
    50641 tatcacggtc ttttattgtg tggggatata ataaatatta atcaatcgag aataaaaaat
    50701 tcatataatg aaatagcgga agaatttttt gagcataata ttcgccaaaa atttatcaag
    50761 tgataaaatt gttgtataaa atgattattt caggaggagg agttaaatgt ttttagcatt
    50821 aaatgaaatt atgcattcaa agttacgtta tgcgttagtt gcaggggtga tgtttttgat
    50881 cgcctacctg gtattttttt tgactgggtt agcttatggc ttagctcaag ataatcgaac
    50941 agcagtcgac aagtgggagg cagattcgat tgtgctttcg aaagatgcaa attcaaatct
    51001 agggatgtcc atgattacta agaagatagc agaagaagtc gaaggtggga aagtggcgta
    51061 tcttgcccag acacctggag tcgtgactag taaagacagt acagaagaag gaaaaatcaa
    51121 tgttagcttc ttcggtatcg ataaaaatca attcatcatg cccaatcttg ttgaaggaaa
    51181 agcttttgat aacgatgatg aggcagtagg cgatattagt ttgaaagaag aatatggtct
    51241 agccgtagga gatacagtta agttatctgg tagtgacaag acgtttaaac taactggctt
    51301 tacggatcat gccaaattca atgtctcacc agttctctat acaaccatca atgcttacca
    51361 agagatccgc ttcgaaaaag aagatacaag tgaaaatgca cggattaacg caatagttgt
    51421 cagaggtaaa atcagtaatt tacctgaaga tttagaacag atcaaaattt ctaaattcat
    51481 caatgaatta cctggatata atgcgcaagt attgactttt ggatttatga tcggattttt
    51541 gatcgttatt gcggctattg tgatcgggat tttcatttat gtactgacga tgcaaaagat
    51601 taatatcttt ggtgtaatga aagcacaagg gatcacagga ggatttattg cgcgttctgt
    51661 agtggcacaa acattcattt tatcatttgt tggtattctt cttggtctat taggaacagt
    51721 gggaacatcc cttgttctac ctgatgcggt tccattccaa agcaattggc tgttttttgg
    51781 cgtcattagc ttgttgatgc tggtagtagc tgtgttaggc gcactatttt ctgttcggac
    51841 aatcgtaaaa atcgatccgt tgaaggcaat tggataagaa ggaggaagag catgaaagca
    51901 atagaattta aagaagtaga aaaaagtttc caagatggcg accaagtagt taaagcattg
    51961 aaagaaacaa ccatgagtat cgataaaggg gaatttgttg caatcatcgg tccttctggt
    52021 tcaggtaaaa gtactttttt gactttggca ggcggattgc agacgcctag cagtggctct
    52081 gtatttatca atgatcaaga attcagtaat caaaaagaaa gtgaacgcgt taaactacgt
    52141 tttaaagaaa ttggctttat tttgcaagct tccaatctgg ttccttttct gacagtaaaa
    52201 aagcagttat tattagtaga taagatcaaa catgaacatc gtcaaaaaga agcaaaagaa
    52261 ttatttgagc agcttggcgt ggataagttg atcaacaagt atccagaaga actatctggt
    52321 ggagaacggc aaagggtcgc aatcgctcgt gcattgtaca atgatccgtc cattattcta
    52381 gcagatgaac caactgctag tttggattca gaaaaggcac gagaagtagt cgatatcttg
    52441 gcaaaagaat caaaagacaa aaataaagca acgatcatgg ttactcacga tacacggctg
    52501 attgacaaat gcgatagaat atttatgatg gaagatggtg tattgaaaga aaaagaataa
    52561 ccaaaaagca ggtggaaaaa tggtccatcg atacaacaaa gatacacagc aaaaaatttt
    52621 gaaagaagcg actgacttgt ttatgtccaa gggatatctc ggcacttcaa caagagagat
    52681 cgcacaaaaa gttgggatca cccaacccaa tctctatcat tatttcggtg ataaagaaaa
    52741 actatatacg gcagttttag aaaaccactt aaaagatgtt ggaaaagctt tgagagaaat
    52801 cgttcaaaca agcgaaacgg gatttcaagt aaccttgaca aaaatggcgc agtttttgat
    52861 tgagacacat ctggtcgatt tgtttctgat gcttcacgat cttgaaagca atctttcaaa
    52921 ggaaacaaga gatcatcttt tctttctatg gaagaaaaat tatcgtgaac cttttgaaga
    52981 aatcttttca gcaaaccaat ctgtgctaag aaatgggatt tcaaaagaaa tcgcagcaag
    53041 gcattttttc ttagtgttag caccttacat cactcggtcg aaaagacctg tggaagaacc
    53101 gctaaatgtg gcgcaattga tcgatttata tttgaatggt gtattaggag aagcgtaaag
    53161 ctgttatata gggagaaaaa tagttaggtg aagaagcaag atatgacgaa gatcgttata
    53221 tcttgttttt tttatatagg tagtttttca taaatacaaa tttgttattc tctcatgatt
    53281 atcagggtat atttttattt attatgtcgg tgttccagga agtgttttaa tttaataacg
    53341 aagaaattaa ttgtttgtag aatgaaggaa actatttatt gggtagatga atcaccacga
    53401 atagtcaaaa ggagatttca ggatatgcca aaaatgaaaa aaatcatttt agcagtaatg
    53461 ttattttcta cggttatatc ttttacagcc ccttttttgc gtacttaagc tgattttaag
    53521 ttttgaccct tagtctggat ctacgaggtg agagtcaaga atgaaaaaaa taattggagc
    53581 ttttgtattt gcaatcatta tcattattat ctgttttcaa atagatgttt ttggtcaaaa
    53641 aaagatagtt ggacaaacgg tcagcagtac gaacagtacg gttacaaaga caaaggaatc
    53701 atttgatgat acagaacaag agacattaat caaaatcgga aaaaatgacc gtacactata
    53761 tacagatgac tcgctaacta ccccacttgc aactataaac ggcggagagc tggcggagtt
    53821 tctttctgaa acaaaaaatg cttatcagat caagacaaat gatggctata ctggatattt
    53881 agccctcgaa gatggaacca aagtcacaaa gaatatacaa acaaaaccgg aagagctatc
    53941 tgatgcagtg attgtattag atcctgggca tggcggaaat gatactgggg cattaagcaa
    54001 tgatgaacaa acagaagaaa aagatataac attaagtaca gccataaaag taaaaaaggc
    54061 gctagaggat gctggagcaa cggtttattt gacccatact acagatgaat tagtacagct
    54121 tggagatata tgcgactaca gtgaagaaaa aaaggcagat gtctttatca gtttacacgc
    54181 agactctacg gaatatgcga atgaagcaac tggaatcacg acatattatt actatggaca
    54241 agaggaaaca ttagcacaga caattgctga ctccttcact gatctgcctc tggattcaag
    54301 aggaatctcc actgggaact atcaagttct tcgagaaaat cttcaacctt ctattttaat
    54361 cgagatgggt tatatgaata atgatagtga tttaaaggaa ttagtaacag acagttatca
    54421 gcagcagatt gctgcaagtt tgacacaagc attgaccact tattttcagt aataaataag
    54481 cccagccaaa caaaaatagc tcctcatatt tttcgtttgg ccgggcttat tatcgcagat
    54541 gcaagctttt gaacaccgtt taaggaagag gttgtgagcc tgccgtttaa ctccgcgtca
    54601 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga ctattgtgac ttgtgaccga
    54661 ggagttggca tgagaacacc gtttattcgg aacaagggac tgtgacatga cttttgtcac
    54721 agttccatta tttttttagc agcttcaaag ctttttctgt attggcaaaa tgaagtttgg
    54781 catatttttc aagcataggc atgccgcctt tctccaatag ttttgccgct acttggtcag
    54841 atttcgttcc agctcctgat ggaagggtga ttccagcttc agctgatgct ttgtgtaact
    54901 cttccaaaaa gctggcacga ctgatgatag aagcagcagc aacagctaaa tgatattgtt
    54961 ctcctttagt aacgaagtac agtttttctt gtaattgatt tttttctaaa cgcgcatatt
    55021 ttttaaaatt tgcttccggc gtaaactgat cgatcaaaat cgcttctggt ttttctggct
    55081 cgattttttt tagcagcaaa tggatcgctt gattgtgcaa agcgactttc atccgaacgg
    55141 cattgtattt tggttggatc tcattgtatt tttctggaga taagacaagc agtttatagg
    55201 ggatggtttt ttttaagatg tcagcaagct ggatgatttg gctatctttt aactcttttg
    55261 aatctctaac accaagttta cgtaattctg caagctgatc acgtttcaca taagcagcac
    55321 atactgttag cggaccaaaa tagctgccat ttccgacctc atcactacct aaaacggata
    55381 attgactgat attttttggc aaagaagagg ctgtttttgc tggcttggct tgtttatcct
    55441 gtgcctcccc ccatttatca gcttctattg ctgcattcgt accttgaaac atcacttttc
    55501 cggatgtata agcggtaatg gtcgtcccgt ctttttttgc agcaaagcta gtataaggaa
    55561 tctgtttatt taacaaataa gagcgatagt atgctttcat ttgactaagt tggtcgtttg
    55621 ttgctttgat aatgacgttg ctcataaaat tctcctcgtt tttatacata aaactatacc
    55681 gcaactcacg acttttcgtt ttctaagaga ttgcgagaca tagcattttt ttaaagttta
    55741 tcatataata gttaagtatg tgaaaaatat ttgtggagaa cggtgaaaga accaacttca
    55801 tggtacacta aataaaactt tcatcaaata ggaggaaatg attcgtatgg cgcacgaaaa
    55861 aacacgctac aaagcagtga ttgccaacca aacatatact attatcggac gggaaaccaa
    55921 gcatcatatg gatatcgtaa cgaagctgat caatgaacag ttagcagaat tgaaacaatt
    55981 atcaccacaa atggataatg aacaagcagc aatcttgatg gctgtcaatg cgctttcgga
    56041 tcaattgaag aaacaagaaa gaatcttgga gctggaagaa gaaacagcag aattaaagaa
    56101 aaaaatgatc aaatttacag agcttgaaaa tcgtgtgaaa cgcattgaag caatcgagaa
    56161 cgaagctcgg gaagtattga aagaaaatgg tcaagcagat cataccatta aaaatcatgt
    56221 ggaagcacaa cagattttaa acgagaaacg aaaaggacaa attaaacaaa aatcttctaa
    56281 ttaagatcct tttatcaaaa taagaaaaat ttaaaaaagt tagaagagaa aggaacgtag
    56341 catgctgagt ttgctgattt tatttttatt gctaattgcg tttttttctg gagcacgtcg
    56401 cgggtttgct ttgcaaatca tattcgcgat tggatatgta ttgtcattta ttgctgccca
    56461 gcatttttac aaaccattag caagtcattt ggaattatac attccatacc cagctgtcac
    56521 cccaacatca aagttagcat tttttgatca ggtatttgct tttcacctag atgaagcttt
    56581 ttatgcagga actgcttttc tgattatttt gctaattggc tggctgctta cccgatttgt
    56641 gggggttttt gtccatggat tgacgtatgt gccgatcttg agacaggtag actggattgc
    56701 aggaggcatc ctgtcactaa tcatggctta cgttactata tttttgattt tgcagttact
    56761 tgcctttgtt ccattagtgt ggtccaaaat caattcggcg agcatagttt cgctcgtttt
    56821 atcgttgaga gaacgccatt tcttaccaac aagatgtatg agctttgggt aacgaatatt
    56881 ttgaattaag gaaaatagtg ctggaaaata tttcgttttt tgtacagagt agtttattta
    56941 agaaggctgc gtagcgtatg tccggcacag ctcttttttc atagtgaaag ataaggtgat
    57001 aaaatgaata accgaatcct tgaaacattg gaatttgaaa aagtcaaaca gatggtcaga
    57061 caatttgtag tgactgcaca aggaaaagaa gaactggcag aattggtacc agtgagtgag
    57121 aaacaaacga tcacaaactg gcttcaagaa actgaggatg gattgaaagt gcaacgtctg
    57181 cgaggcggga tccctatacc taaacttgaa aatatccgtc cccatatgaa acggatcgag
    57241 atcggagcag acttgaatgg agtggagctt gcacaagttt ccagagtatt gtctacgaca
    57301 agcgaattga atcgtttcat tgatgatctt tctgacagtg aaatcgaatt tgcacgtttg
    57361 tatatgtggg cagatcagtt agtcacgatc cctgttttga gccgccgttt aaaggaagca
    57421 atcgatgaag acggacgcgt gactgatgac gcttctcctg agttaaagag cataagacag
    57481 aacattcggc gaagtgaaca agctgttcgt gaacagttag atgggatcgt ccgtgggaaa
    57541 aatgcaaagt atttaagtga tgcgatcatc accatgcgaa atgaccgcta cgttatccca
    57601 gtcaaacaag aataccgcgg tgtatttggc ggtgtagtcc acgatcaaag tgcttcagga
    57661 cagactttat ttattgaacc aaaacaagtg gtggatttga ataatcgttt gcgtcaatac
    57721 caaatcgctg aacgaaatga gattcaacgt attttaagtg aactttctgc tgaacttgtt
    57781 ccccatcgtc aagaaatcat ccacaatgct tatgtgattg gtaaaatgga tctgatgaat
    57841 gcaaaagcac gatttggtaa agaagtaaaa gccatcgtgc cgggaatcag tgaagacaat
    57901 catgtcgtct tgaaacaagc aagacatcca ctgatcgatc aggaaaaagt agtttctaat
    57961 gacatcacaa tcggaaaaga ctatcaagcc atcgtcatta caggacctaa cacaggtggg
    58021 aaaacgatca cgttgaagac tttaggtctg ttacaactga tggggcaagc aggattaccg
    58081 attcctgcag gtgaagaaag tcaaatcggt atttttgagg aagtatttgc ggatatagga
    58141 gacgaacagt cgattgagca aagtctatcg accttttctt ctcatatgac gaacactgta
    58201 gatattttat caaaagtcaa tgaaaaaagt ctggtattat ttgacgagct cggtgcagga
    58261 acagatccgc aagaaggtgc tgctctagca atcgcaatct tagatgatct tggtaaaaag
    58321 tctgcttatg tgatggcaac aacgcattat cctgaattga aagtttatgg atacaatcgg
    58381 gcaaatacga ttaatgccag catggagttc gatgtggata cactaagtcc aacgtatcgt
    58441 ttgctgattg gcgttcctgg acgaagcaat gcgtttgaaa tctctagccg attaggtctt
    58501 gatacagaag ttattgatga agcgaagcag ttgatgaatg atgagagcca agatttaaac
    58561 gaaatgatca cagatttaga gaatcgccgg aaaatggcag agaccgaata tctggaaatg
    58621 cgtcattttg tttctgaggc acaagaactt cacgatgatt tgaaagaagc ttacagctat
    58681 ttctttgaag aacgtgaaaa agaaatggaa aaagcaaaga aaaaagcaaa cgaagtcgtg
    58741 tcagaggcgg aagaaaaagc agaaaaaatc attgctgata ttcgtaaaat gcaacagcag
    58801 attgggcaag gaaatgtgaa agagcatcag ttgatcgatg caaagaccca attagcaaat
    58861 ctacatcaag aagaaacttt gaagaaaaat aaagtattga agaaggcgaa agaacaaaaa
    58921 acgttgaaac cgggagacga agtgttggtt acgacttacg gccaaagagg gacgctttta
    58981 cgtaaaaacg ggaatcagtg gcaagtagaa atcggtatat taaaaatgaa tgtgtccgaa
    59041 gacgagctga cgcctgttgc tcctcaaaaa gagccgacac aacgagttat ccatgctgta
    59101 cgatctgaat ctagtagtca cgtgccgaat caattggacc ttcgaggaaa acgatacgaa
    59161 gaagcgctaa gtgaggtaga tcaatatttg gattctgcca ttctagctgg ttatcctcaa
    59221 gtgactattg tccacggaaa aggaacaggc gcacttcgca agggaattac tgattatctt
    59281 aaaaaccatc ggagcgtcaa aagctttgag tttgcaccgg caaaccaagg cggaaatggt
    59341 gcgacaattg ttaaatttaa gtaaagctta ctaaaggtaa gcagatggtt cgctatccaa
    59401 gtatagaaat gctatactaa tcatagattt taaaaatgga ggtctttgat atgtcacaag
    59461 taattacaga taagacattt aatgaagaaa cagataaagg acttgtattg attgattttt
    59521 gggcaacttg gtgtggtcca tgtcgtatgc aagcaccgat tttggatcag ttggaacaag
    59581 aatatgatga agaagaattc agaattgcta aaatggatgt ggatgaaaat ccagaaactc
    59641 ctcaacaatt cggtatcatg agcattccaa cattaatgtt gaaaaaagat ggtcaagtag
    59701 tagaaaaagc tgttggtgtt cattcaaaag aacaactacg tcaaatgatc gatcaatatt
    59761 tataaaaact tacagcaaaa ataagctgag ggtgggactg aatccagttc cgtcctcggt
    59821 ttttttgcgg ttgagttaag gttattcaaa ttaatatttt ttgagtataa ttacgttgtc
    59881 aggctggatt gtttttttga cagacatgct ataataactt taattgaata tgaaggggag
    59941 taccagatga acgaacgaat caaaaacaaa ttagctttac ttcctgatca gcccggctgt
    60001 tacttgatga aagataaaaa tggaacgatc atttatgtcg gcaaagccaa aatattaaaa
    60061 aatcgtgtcc gctcatattt tactggcagc cataatacga aaacggaacg gcttgttagt
    60121 gaaatcgaag actttgaata catcgttaca gaatcgaata tcgaagcatt gctcttagag
    60181 atcaatctga taaagaaaaa tgatcctaaa tacaacatta tgttaaagga tgataaaacc
    60241 tatcctttcc ttaagataac gaatgaaaaa tatccccgtt tggtgattac tcgtaaagta
    60301 ctaaaagaca aagcactgta ttttggacca tatcccgatg tcggtgcggc gaatgagaca
    60361 aagaagatcc tcgatcgatt atttcctctg agaaaatgca aacctagtca gacgaaggag
    60421 ccttgtcttt actatcattt gggacaatgt ctgtgtcctt attatttcga cgtagatccg
    60481 aaagtctata cgaaaatcgt tgatgaagtg aaaaagtttt taaacggagg acacgaaaaa
    60541 atcgagtcag agatccatca gaaaatggaa aaagctgctg aaaacatgga gtttgaaaaa
    60601 gctgcagaat accgagacca gatccgtgcc attgagacaa tcatgactcg ccaaaaaatg
    60661 acaaatactg atttactgga tcgagatgta tttggttatg cgattgacaa aggatggatg
    60721 tgtgtccaag tgtttttcgt aagacaagga aagctaattg aacgagatgt ttcaatgttt
    60781 cctttctata acgaagcaga agaagatttc ttgacttacc tcggtcagtt ttatcaggaa
    60841 aatgagcatt tcattcctaa agaagtcttg attcctgata cgatcgacaa gcccagtgta
    60901 gaagctttgt tagctacgaa agtgctgcaa ccaaaacgag gagaaaagaa aaaattagtt
    60961 gaattggcga ataagaatgc ctcagttgct ttgaatgaac ggtttgatct gattgccaga
    61021 aaacaggaac ggacgatcgg agcagttgaa cgtttaggaa acgcgatgaa tatcccgacc
    61081 ccaatacgta tcgagtcttt tgataactct aatatcatgg ggacgaatcc tgtggctgcg
    61141 atggtcgtat tcattgatgg aaaaccggca agaaaagaat atcggaaata taaaataaaa
    61201 acagtcaacg gaccggatga ttatgcatca atgagagaag tcatctatcg cagatattca
    61261 cgagtgattc gcgaagggtt gcctttacct gatttgatct tgatcgatgg aggaaaagga
    61321 caagtagatg tggcaaaaga tgtcttagaa aatcaattag gaatcgatat tcctattgct
    61381 ggcatggcaa aaaacgataa acataaaaca aatgagttgc tattcggtat agatttggct
    61441 gtagtaccgc ttgagcgaaa ttcaccagag tttttcttac tccagcgaat ccaagatgaa
    61501 gtccatcgat tcgcaatcac tttccatcgg cagctacgca gtaaaaacag ttttgcttcc
    61561 cgattagatg aaattgaagg gttaggacca aaacgaaaaa aaatgctgct taaagagttc
    61621 aaatcgttga aaaatatcac agcagccacg acagaagaat tacaagaaat cggactgccg
    61681 aaaaatgtcg cacaaaacgt atttgataaa ttacatcagg aatgaggaaa gggcacttta
    61741 caaagaaagt aaagtgtcct atcattttat gtacaacaaa aagagcgttt acgttttgtt
    61801 ggtaaataat aaatcgctta cgtctggtgt ctaaggatat atgtgatttc ttgaagaagg
    61861 agtgaagaaa tgttagaagt caaggatctt gttaaaactt ttgggaacta cacagctgtc
    61921 gatcatgtct ctttccaaat ccccgatgga aaaatcatgg ggctaattgg ccaaaacggg
    61981 gctgggaaga caacgacttt tcgtttgatc ttggattttt tgacacaaga ccaaggagaa
    62041 gtgttatgga atggccatca tcttggggag aaagattatg atgtcatcgg ttatcttccg
    62101 gaggaacggg gactttatcc gaaagtaacg attcaagacc aactgcttta ttttgcagaa
    62161 cttagaggga aatcaagaaa agagattgaa ccaaaaatcg atttttggat ggaaaaattt
    62221 caggtaaaag ggaaaaagac ggataaagta aaatctttgt ctaaaggaaa tcagcaaaaa
    62281 gtccagctga tcgccacgtt aatccatgaa cctaaattga tcattttgga tgagccattc
    62341 agcgggttag atccggtaaa tgctgaattg ctaaaagatg gaatattgga attgaaaaaa
    62401 catggttcat gtgtcatttt ttctagccac aatatggata atgtagaaaa aatctgcgat
    62461 catttgatca tgttgcgaaa cggaaaaatg gttttgaatg gaaaagtaca tgagattcgt
    62521 gaatcatttg gccgtacgaa gttattcttg gaatctggtt taagccaaca ggaagtagaa
    62581 gaaatcgaag gcgtgaaaaa agtgatcctt catgaagaca atacgttaga gattacctta
    62641 gaagatcctg aagctgggaa agaaatcttt actcgtgcga ctcagttcgg ctacattcct
    62701 atgtttaacc agcaaccgcc aactttggaa gagattttca aattgaaagc aggtgaaatc
    62761 gatgcgtaag ttttggatta ttaccaaaga tgtctattta aaaaatgtta agtcgatttc
    62821 tttcttgatc atgatattag tcccttttat catgctgggt atcatttatg tagcaggaaa
    62881 ctttgctcaa caaaatagtg atgtcaataa aatcggcgta ttggctgata atgagcaaat
    62941 cagtcagcaa atgagccaag tcaaaacaga tgattttgag ttcaaagcag ttgattctga
    63001 agaaaaagca caaaaagagc tttcggaaga aaaaatcgat gcgtatttag tagtctcaac
    63061 tgagaatgat aagataaatg ggatgcttta tagcgaaaat tcattaggac aaagtacaca
    63121 actactgata caacaacaac tgactggctt gcaatcgatg cttcgagcaa gtcaattagg
    63181 catttcacca gaagaagtag ctagcttgag ccaacaagca agtttgactc gacaaaaagt
    63241 caattttgat tcaaaaggaa aaatgacagt tggagaagat aactcgacag tccaatatgt
    63301 cgtaagttat gtagcaacga ttgtcttgtt cattattatt ttgacgtatg cgcagatcat
    63361 tgcacaagag atcgcttctg aaaaaggcac gcggatcatg gaagtgatcc tgtccagtac
    63421 gactgcacaa aagcattttt acggaaaact aacaggtgtt ttacttgttg cattaacgca
    63481 aatggcatta tacggtatta tttttggtat aggatacagt caattcaaag atatggaaat
    63541 ggtcaaaaat atattagacg gtatctcatt ggataacttg attggaccat tcttgtggta
    63601 ttctcttcta ttcatgatct ttggcatttt gattttttct gttttagcag ctttatgtgg
    63661 ctctttggtc aacaaagcag aagatacagc aaaagcaatt ttgccagtga cttatctatc
    63721 tctaggcgga tatatgcttg gattgatact aggagcttca gatccaaaca atatcgttat
    63781 tcggatcact tcgtatattc cattcttatc ttcatatatt atgccggttc gcttagcaaa
    63841 tgagacagtc ggtatgggtg gagcattgat ttccttgttg gtacttgtag ccgtaacatt
    63901 cttattgatg atcttgtctg caaacatgta caaatcgaat gtactcgtgt atagcgaagg
    63961 cggattatgg agttcattga aacaatcgat ttcaattatg agaaatgaac gaaaaaaagc
    64021 ataaaatata gaaaaatata gaaggaagct ggacatttat tgttcccagc ttcttttttg
    64081 tatagaccta tttctatttt tttattatat tggatatata tattcattga aaatagagca
    64141 taacaacttt ataatgttga gtataccaat ttttggaggc gttttaatgg accgctattt
    64201 agatttactt tcagagaagt tccctacaac ggaagatgtc atcacggaaa tcatcaatct
    64261 cgaagcaatt ttgcagcttc caaaaggaac agagttattt ttgagcgata tacatggcga
    64321 atttcctgct tttgatcata ttctgcgtat cggttcagga aatcttaaag aaaagatcaa
    64381 agaccttttc tctgaacaaa tgacggaaac ggagatcagc caattcacta tttttacggc
    64441 ttatccagaa tatgtgttga cgactgattg gtacaaaaaa caagataaat cccagctgat
    64501 ccatcgtttg atcgatcttt tacggtttac gacagtcaaa tacactcgat caaaagttcg
    64561 aaaaggattg ccgaaagaat atagctatat cattgaggaa ctcttgtata tcgatgatcg
    64621 tatcaacggg aaaaaagact atgtaaaaaa aatcattgaa caacttgtct tgatgaagga
    64681 agaagaaaaa tttttaacaa aacttgcgca gacgatccaa aaatctgtca tcgatcattt
    64741 gcatatcgtg ggtgatattt ttgatcgagg aactcaagca gccaaagtaa tggatcgaat
    64801 catggatttt tcctctgtag atatccagtg ggggaatcat gatattttgt ggattggtgc
    64861 gtattgcggc tctgaggcat gtttattgac gcttttacgg attgccgcac gctacaacta
    64921 tttatttgaa ttagagaaag aatatggatt aaatttacgt ccattatttt cttttgccca
    64981 tcaaacctat cagaagaatc cagtatttac ccctaaaaac aggaaagatc tatctgaaag
    65041 agagcaagaa gaattagaaa agatccatca agcactttct atcctccaat tcaaatcaga
    65101 acatcagttg ttgaatcgac gacctgaatt taaaatggac gatcgtaaat tgttggaaaa
    65161 aatcaactat gaggaatcaa cgatcgtttt agaaggtcag ctctatgagt tgaaagggac
    65221 ttgttttcaa acgatccagc cagatgatcc taaaaaattc ttggaagagg aacaaaaagt
    65281 gatcgatagt ttgatgtatt cattccagca ctcgttaaga atgcaaaaac acatgacgtt
    65341 tttgatcgaa aaagggggaa tgtatctcac gaacaatcag catgtactgt tccatggctg
    65401 tatacctgta gatgaaaagg ggcagctctt agcatttgaa ttagaccaat cttatcgcgg
    65461 aaaagaactg ctgggatttt ttgaaaaaca gataactgaa agcgcaaaag atttgactgc
    65521 aaatgaagat ttggcgaccg atttgatttg gtatgcgtgg agcgggccat tttcgccttt
    65581 attcggcaag agtaaaatgg caacttttga gcgctatttt ctcacagagc ctcatacgca
    65641 cgtcgaaaaa agcaatccct attatcactt gcgagatgaa gagtggttca gtgaaaaaat
    65701 tttggcagaa ttcgatgcaa aagaagaagg ttcagcaatc atcaatggac acacgccagt
    65761 aaaagtaaaa aaaggagagt caccgatcaa agcaaacgga aaagcatttg ttattgacgg
    65821 aggtctatcc aaagcttatc aaaaaacaac cgggattgct ggctactcat tactatgcaa
    65881 ttcttacggt ttccaaatcg tgacacatta tccgttcttg cctattgaac aacaatttgc
    65941 aaaaaaatct gatcaaacga atgtaaaaaa agtgatcgag cagcagctcc cacgcaaact
    66001 taatcggaat acgacaaaag gaatggaatt acagcaacag attactcaac tccaaaggct
    66061 gttggattat cgaaaggacg attgagaaaa atgctagcca acattgctca atagactaaa
    66121 aagcgactgc aacaaaaggc gtgtcgcagt ctccttcgga attagctcaa aaaacggtaa
    66181 aatattagaa gctatttttc tgtttatttc tctaatactc aggtcagggc gctgatttca
    66241 cgacctcttc cttaaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca
    66301 acaaacatga gaagctgttt tttgaaattg ctccttgtga ctcagagttg aacggcaggc
    66361 tcacgaccta atcagaaaaa cgattaaaat tcattcacaa agaaatcgaa taaacgctgt
    66421 tcagatgaat ctacacgatg agaaagttcc ggatgccatt ggacaccaag gattttgtgc
    66481 atattatctt tactttggac tgcttcaatg agtccatcgt tggaaaaggc gatggctttt
    66541 aacaaaggag aaagatcttt gactgcctga tgatgatagg aattcacaaa gtatgaatca
    66601 gggagaaggt cacttaataa actgtccgaa acgattttga cttcgtgagt tgcaaactgc
    66661 ggggcagtgg gctgttgttc gtgttttacg gaccattttg gatataatga aagatcttga
    66721 taaagtgttc cctccaacac gacattcaat agttgaagtc ctcggcagac tgcaaaaatc
    66781 ggttttcttt gtttcaatgc ttccaagatc aatgcctgtt cgaattggtc tcgttgaata
    66841 tttgtttccg tcagttttgg atgagggtct tccatgtaaa gttgcggact aacatcctga
    66901 ccgcctgcaa gaatgagttt gtcgattttc tcaattagtt gaggcgctga atctggagac
    66961 atgactggca gaataagagg taatccttga gcatctaaaa ctgcatccac aaatccctgc
    67021 ggtgtatagc ttacttgatt tccttggaaa gtatctgtcg ctcgaatcag ttgattcccg
    67081 gcaatgccga tgattggttt catttttatt ccccctaaag tagactaatt gtaacaagga
    67141 tttaaaaaaa tttaaactat gtaagacttg cccctatact tatctgttct tgctgtgtta
    67201 ctatctgtaa agagaatttt cgtgtgaaat tcatgacgat agttgaaaat attgcttaat
    67261 ttgttataat aaaaagtaag cagaaataaa aaggttgggc gtaagcttca aggatctagt
    67321 tcttcaaggg gtgagaagga cattttattg aaggggcctg cctatactaa gttatcttta
    67381 gaggtacata ctttcaatga aaaaagaaag catgtacctc ttttttaaat cgaaaggaag
    67441 tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc agaagaagaa aatgagaagc
    67501 gtgctcgaac cctacggcag cagttgaaga cctatgcaga agaaaaagag caagaattgg
    67561 agataatcca aacgaacagt cggcaacagc tgaaacagtt ggtagaagaa aaagaacaat
    67621 tcgaaaagca agaattagaa aaagaaaaaa tgaaattgaa agcagaagca gacaaggtgc
    67681 aagcaacttt gaaagaccaa tatcaaaagc atcagagtca agcaatcggt gcaatcattg
    67741 aaagggtgaa agaaacttat ggccgtcact aagatggaaa aagtgaccct catttcagat
    67801 aaaagaaatc aggagaggat tttacaagca gtacaaggaa tccaaaatgt tgaaatccgg
    67861 gatctgtatc aaaatagaac aaacaaccag tgggtagaaa aatattttcc agataccacg
    67921 attattgata aagaagcaaa attaagcgct ttaggcaatc ggctgaaaga catccaagaa
    67981 gctatccaat tcatacaaca ccacggcgat agccgtcaaa agaaactcca tttgaaacgt
    68041 caagaacttt ccttacaaga cttggaagca aattattccg aagaaaattt catgaataaa
    68101 ttagaagaag tccttgattt aaaagaaaag tgggaacagc taactgaaaa acgtgatcgt
    68161 ttagaagaag aggaagaatg gcttcttcat tggcaacagc tggatattgc tccaagtatg
    68221 tatgcaagta agacgaccat ttttgagatg gggactgtga gtgcagcaaa ttttgaaagt
    68281 ttcaaggaag aactaagtaa gcttgatgac gtttatatgg aagaaataga ttatacgcca
    68341 aaacaagttt atctttcgta tgttgcttta aaaaaatcag ttgctgctat agaagaaatt
    68401 gctgggaaat acgggttcaa taaagaaacg tatccttatg aacaaaatcc taaagaaaaa
    68461 ttgcaagaaa ccaaacagca attatccatt gttcacgagc agcaaaaaaa gataacgaca
    68521 gcgttaggtc agtgcagcgg ctatatccaa gaatttgaat gggtagaaga agtcacactt
    68581 gccgttgcag aacgggaaaa agtaaaagaa cggtttatcc atgccactta tctgatcgtt
    68641 ttgcaaggtt gggtagatgc agaagaaaaa cagaatttga tgcatgtgtt aaacgaaact
    68701 gtatcagaag aagatatata cgttagtttc gaaacaccaa actcagaaga gattcagcag
    68761 gaagtcccta ctaaattgaa aaaccatccg cttatcgaac cttttgaatt gctgactgaa
    68821 atgtacagtc tgccaaaata tgaagaagta gatccaacgc cttggatgac accattttat
    68881 cttgtcttct tcgggatgat ggtcgcagat gttggttacg gattgctgat gctcattggg
    68941 acaatactag ctcaaaaact atttgtttta ccccgcggga tgaaacgttt cgtaaaattc
    69001 tttgagattc tctcggtacc atcgatcatc tggggattga tctacagttc atttttcgga
    69061 caggcattac caaaagaact atttggtatc cgcttgcctt tcccaatcct atctacgacg
    69121 gatgacgtca atacgatttt gattttatcc gtgattttcg gtctgataca gatcttggtt
    69181 ggattattcg tggcagcaaa ggaaaatatc aggaggaaag attacttgag tgctgtcagt
    69241 gatggttttg cctggcaagg gatcctgatt gggatcgtta ttgcattgat tggtgtcatg
    69301 ttgataaaaa atacagcatt tgtttatctt ggcgcggggc tatcgatcat tgctgcttta
    69361 tgtatcttaa tcgtgccgat tatccaatcg ccgtctaaag tcaagggtgc tgccaaagga
    69421 gcgtataatc tttacggatt gactggttat atcggtgatt tagtcagtta tacacgtttg
    69481 atggcactag gtatttcagg cggaagtatt ggcgcggcat tcaatatgct agttgctttc
    69541 atgccgccag ccgctcgatt cagtgtaggg atccttttga tcatcgcttt acacgcactg
    69601 aatatgtttt tgacactgtt aagtgcctat gtccatggtg cacgattgca gtatgtcgaa
    69661 ttttttggaa aattttatac aggaggcgga cgtgcctttg acccgctgaa aacggcggaa
    69721 aaatacgtca acatcaatca taagaaaaaa aacaataaat aattggagga tttttataca
    69781 atgatggatt acttaattag tcaaaatggt ggaatggtat ttgcagtatt agcgatggca
    69841 acagcgacga ttttttcagg gattggttca gctaaaggtg ttggaatgac aggtgaggca
    69901 gcagcagcgt taacaacaag tcaacccgaa aaattcggac aggctttgat tctgcaattg
    69961 cttccaggta cgcaagggtt gtatggattc gttatcgcct ttttgatttt tatcaactta
    70021 ggaaatgata tgtcagttgt acaaggattg aactttctag gcgcttctct gccgattgct
    70081 tttacaggtt tgttttcagg tatcgcccaa gggaaagttg cagcagcagg tatccaaatt
    70141 ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt ttgctgcgat ggttgaaaca
    70201 tatgcgattt taggtttcgt tatttccttc ctattagtat tgaatgccta agcataaagg
    70261 aggaaaagca gatgaacgcc attgaaaaaa tcatctctca gatgaatgaa gcagcagagc
    70321 aagaaagagc ggcgttagag caagaagagc gaatgaagat cgatcaaaac tttgaacaaa
    70381 aacgtacgca aatcgaaaca gaacatcaaa aacaaaaaga aaaacaaatc gaattacttg
    70441 aaaaaaaata ccgtcagctt aggaatcgcc aacaagtaga agtacgacaa gaaaatttga
    70501 atgcgaagca ggaattttta cgacgattgt ttgcagatgc aatagctgaa atggagaatt
    70561 gggatgaatc tgaacaaatc cagtttatca aaaattcatt gtattcatta cctttgacag
    70621 gcaaagtaac attcattgct ggagaaaaat cagcagctta tctttctcag acattgctgg
    70681 atgaatggaa caatgaactt ccctttatga tggttttaag tgatgaaact gttgctgatc
    70741 aagcgggttt tctgataaac gatcaaggag ttcagtataa ttttcttttc agcagccttg
    70801 tacaagatat ccaaggaacg atgagttttg agattgccaa tcaattattc gaataaggag
    70861 ggatcagtgt atggaatacc acgaactaaa tcccttgatt cgcggaagag agcttgaact
    70921 tttgtccaat gagacatttg aacggatgat tcaaacaaat tctgtcgaag cacttggtga
    70981 aatattgaaa tccacgattt acagtccata tatttatgac ggatatgaat atgacttcga
    71041 acagaatctt ttaaaggagc agagccgtct atttcgctgg ttaaaggaat cagcaccgga
    71101 gcctgaaatc gtttggatct atacgatgcg ctatactttc cataatctga aggttttgac
    71161 aaaagccgag atgacaaatc aaaatctgga ccatttgtat atcgacgatg gattttattc
    71221 attagaaacc ttgaaggatg ccattcatac gcaagtttca aatgaactcc ctgaaagcat
    71281 tatggacagt atacgagaag tacgtgatta ttttgaagag tctaccattc ttcagggaat
    71341 tgacgtgatt tatgatcgac agtttttgac agagcagcga cggcttgccg ataagctagg
    71401 atatcaagaa ttgctgacag aagtcattgc ttttattgac ttgaccaata tcacaacgat
    71461 ggctcgagga atattgcaga aaagaacata tgggttcatg acgacggtac tttccagctc
    71521 gggaagtatc gaaaaagaag tatttttgaa ctttgtagat aaagatatgg aagattacac
    71581 gaattttcta ttagagacag attatgctga ttttctgcgc cctgtcatcc gtgagggaaa
    71641 tcttgatctc gtaaagcttg aacagttgaa agatgattat ctaagttcat tgtatcaaga
    71701 agcacaaacc caggctttcg gaccactgcc actactagcc tttttgaacg caaaagaggt
    71761 agaaagcaaa aaccttcgtt tactggttat cggcaaaaga agccatttcg aaccagaaac
    71821 aatcagaaag cgggtgagac aagtctatga cgcataagat cggtgtagtt ggcgacaaag
    71881 attctgtttt gccattcaaa ttgtttggct ttgatgttcg ttatggtaca accaagcaaa
    71941 ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta tggcgtgatt tatgtcacag
    72001 agcaatgtgc agcattgagc ccagaaacga tcgaacgtta caaggaacaa atgatacctg
    72061 ctatcgtatt gattcccaat catcaaggat cattagggat agggctggaa gaaattcaaa
    72121 aaaacgtaga aaaagcagta ggtcaaaata tcttatagta tgaaaaggag atagaaattt
    72181 tgcaaattgg aaaaatcata aaagtctccg gacctcttgt aatggctgag aacatgtctg
    72241 atgccagtat ccaagacatg tgtctagtgg gagatctagg agttatcgga gaaattatcg
    72301 agatgcgtgg cgatgtggcg tctattcaag tatatgaaga gacttctgga attggtccag
    72361 gcgaaccggt tcgctctact ggtgaagctt tatctgttga attaggacca gggatcattt
    72421 cacaaatgtt tgacggaatc caacggccat tagatacctt tatggaaatc acacaaagta
    72481 atttcttagg gcgcggagtt caattgcccg cattggacca tgagaaaaaa tggtggttcg
    72541 aaccaacagt agaagccgga gaaacggtga gtgctggaga tgttatcggg atcgtagaag
    72601 aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg gataaaagga acgatcaaaa
    72661 caatcgaaaa aggttcattc actattgatg aaacagtatg tgtcattgaa accgaaaatg
    72721 gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag acgtagtcgg ccaatcaaag
    72781 aaaaattaaa cccggatgca cccatgatca ctggacagcg agtgattgat acattcttcc
    72841 cagtgacaaa aggaggagca gcagctgtac ctggtccttt tggtgcaggg aaaacagtcg
    72901 ttcagcatca aattgcaaaa tgggccgatg tggacatggt tgtctatgtg ggatgtggcg
    72961 agcgtggaaa tgagatgacg gatgttttaa atgaattccc tgaattgatt gaccctaata
    73021 caggagaatc gttgatggaa cgtacggtat tgattgctaa tacatcaaac atgccagtag
    73081 cagctcgaga agcttctatc tatacgggaa tcacaattgc ggaatatttc cgtgacatgg
    73141 gttatgacgt tgctatcatg gcagactcca cttcacgatg ggcagaagca cttcgtgaga
    73201 tgagcggacg tttggaagaa atgcctggtg atgaaggtta tccagcttat cttggttcac
    73261 ggcttgcgga atactatgaa cgatctggaa gagtcattgc attaggatca gaaggtcgcg
    73321 aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg aggggatatt tcggaaccag
    73381 tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg tcttgattcc agtttagccc
    73441 aaaaaagaca ttttccttcg atcgattgga tacaaagcta ttctctttat tcaacagaag
    73501 tagggaagta tatggatcat atccttcaag ctgactgggc atccatggtc accgagggca
    73561 tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt gcgtttggta gggattgatt
    73621 ccctttcaga taatgaccgt ctgacattag aagtggcaaa atccattcgt gaagattatt
    73681 tgcagcaaaa tgcttttgat gatgtcgata cattcacttc aagagagaaa caattcaaaa
    73741 tgttgaagat gatcttgacc tttggtgaag aaggacgccg tgcgttgtcg ttaggtgctt
    73801 atttaagtga gatcatggac ggtaccgtat cgattcgtga aaggatcgga cgaagcaaat
    73861 atatcccgga aacagaatta gaaaaactag atcaaattat tggtgaaatc aagcaaacga
    73921 tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta aagaatatcg tacgatcggt
    73981 gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg gtgtcaaata tgaagaatta
    74041 atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac aagtattgga agtccaagaa
    74101 gataaagcaa tggtccaaat attcgaagga acaagtggta tcaatttacg tgactcttct
    74161 gtacgatttt taggccatcc tttagaacta ggtgtatcgg aagacatgat cggtcgagta
    74221 ttcgatggtt tgggacgacc gaaagataac ggaccagaga tcctgcctga aaagcatttg
    74281 gatattaacg gagaagtaat caatccagta gctcgggatt atccagatga gtttatccaa
    74341 acaggtatct ctgcaatcga tcatttgaat acattagttc gtgggcaaaa attaccagta
    74401 ttttctggct ctggtcttcc tcataaagaa ttagctgctc agatcgcgcg acaagcaacg
    74461 gtactcgatt catcagatga tttcgccgta gtctttgctg ctattggaat cacttttgaa
    74521 gaagctgaat ttttcatgga agattttcgt caaacgggcg caatcgaccg ttctgtcatg
    74581 tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg ctactcctcg tatggctttg
    74641 actgctgcag aatatcttgc ttatgaaaag ggaatgcatg ttttggttat catgacagac
    74701 atgaccaact atgcagaggc attgcgagag atttctgcag cacggcgaga agttccagga
    74761 agaagaggat atcctgggta tctttacacg aacttagcta ctttattcga acgagcagga
    74821 agaatccgcg gactaaaagg atcggttact caaattccga ttctaacaat gccagaagac
    74881 gataaaactc atccaatccc tgacttgact ggttatatta cagaaggaca gatcatcttg
    74941 actagagagc tttacaagag tgggattcag ccaccaattg atgtactccc gtctctttcg
    75001 cggttaaaag ataagggaac tggacccgga aagacaagag aagaccatgc agctacgatg
    75061 aatcagcttt ttgcagccta tgcacaagga aaacaggcaa aagaattagc cgtagtttta
    75121 ggtgaatctg ctttatctga tgtagacaag atctatgcga agtttgctga gcggtttgaa
    75181 aaagaatatg tcaatcaagg attctacacg aaccgttcga ttactgaaac acttgatcta
    75241 gggtgggaac tgctatcgat gttgccaaga accgaattaa aacgaatcaa agacgacatg
    75301 ctggacaaat atctgccaga agggaagtga gttctgatgg cacgattgaa tgtgaatccg
    75361 acccgcatgg aattgactcg attgaaaaaa cagttgacaa ctgccacaag agggcataaa
    75421 ttattaaaag ataagcaaga tgaactgatg cgtcaattca tcctgttgat tcgaaagaac
    75481 aaccagctgc gtcaagaaat ggaagagtct atgacagaag caatgtctga ttttgtattg
    75541 gcaaatgctt cgatcacgga acctttcatc gaagaattat ttgttttgcc ggcggaaaac
    75601 gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa aagtacctgt gatgaatttt
    75661 gaatatgatg aacagctgac agacacacct ttggaatacg ggtatttgaa ttccagtgcc
    75721 gaactggatc ggtcaatcga tcggtttact accctgcttc caaaactttt ggaactgaca
    75781 gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg aaaagacacg tcggcgagtc
    75841 aatgcattag aatatatgac gatccctcaa ttagaagaaa cgatctatta tattcgtatg
    75901 aagctggaag aaaacgagcg cgcagaagta acaaggttga tcaaagtaaa aaatatgggt
    75961 accactgact aagtggtatc tttttttaaa agaggaaaac gatgattaaa caaagcaaac
    76021 aaataaagaa acgtttgccg gctgttcagc ttctcgcatt aggatttttt ctcctgattt
    76081 tagttggcgg cggcctactt accctaccat tttttagtaa tagtgggcat gggacaaatt
    76141 ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt aacgggattg acaacattga
    76201 atacagcaga gcattggaac agtgctggtc aatttttgat catgcttttg attgagatcg
    76261 gcggtcttgg ttttatgatg gttccgattc tatgctttgc attgataaag aagaaagtca
    76321 gtctcagcac acgtattata ttaaaagaag cgctgaatct agaagaagta tcaggtgtga
    76381 tgaagctcat gctttacatc ctaaaattgg cctttgttat ccaattgatt ggtacggttg
    76441 ctttatcttt tgtatttgtg cctgaatttg gctggttgaa aggtatctgg tacagtttgt
    76501 tccatgcaat ctctagtttt tgtaatgcag ggtttgattt gttaggagac agtttagcca
    76561 atcaccagca aaatgtttat ttgatcatgg tggtatctgc tttgatcatt tctggtgggt
    76621 taggcttcat cgtatggcgt gatttactgg aatatcatca gaaaaagaag atgacgattc
    76681 attcaaaaat cgcattaacc gttacaggta cccttttatt aggcggattc gttgtgttct
    76741 ttttcacaga gcgcaatggg gcaacgctag tggaagggaa tatgtttcaa cgattggcaa
    76801 acaccttttt tatgagtgtg acacctagaa cggctggata ttattcagtt gattacctcc
    76861 atatgagcca tgcaggtctg attttaacga tgtttttgat gtacatcggc ggaacatctg
    76921 ggtcgacggc cggcggattg aaaacaacta cgttaggtgt gttgctgatc cagatgcgtt
    76981 cgatgttgaa aggacgtacg agagcggaag catttggccg taccatccga caaggcgcag
    77041 tgttgcgggc acttacttta ttttttgtta cgttgacgtt gtgtgtagtc gccatcatga
    77101 ttttatcggt gactgaaacg atacctaaaa cttctggcat cgaatatatt gcttttgagg
    77161 tcttctctgc gtttggtaca gtaggtctta cgatgggatt gacgccagac ttgactgcaa
    77221 tagggaaatt gatcattata gcgcttatgt acattggacg agttggtgta ttgactgtgg
    77281 tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa atacaaatat ccagaagaaa
    77341 gtgtcatgat tggataattt catcttctga cagaaaccta gtgatttagt aaaataagaa
    77401 aataaaataa tttttcttgc ttcttggata ctttaagtgc aaaatgttcg tttatttttt
    77461 gaggcactac ccgttgttga acctcgggta gtgcctcttt tttattgaaa ggaatcaata
    77521 agatttgatt cctttattta tcaataggtt ataattcata tttttttatt ttttctttta
    77581 cgatacttag tccagaagct aaaatttcaa ggttattaga ggatagggaa attcgaacga
    77641 atgcatctgg ttgcgcacgt gtagtaaagc gtctggaatg ataaagtcgg ataccgttag
    77701 caagaaagtc attctcaatt atcttagggt caatctcagg atcaactgga agaattcgat
    77761 agtaagggac acgattcgtt ggtttttcta ctttgaaaag agaatcaaaa agttgattgg
    77821 ctctttttgt aagacttaat ttagtttcta agatcctatt tgcttcattt gaatggagga
    77881 tttgagtgat gacttccaca tctaatccag aagttttcac atttatatta aaaattgctt
    77941 gttctatctt gctttggaca tgtactggaa ctacaagata agcaactcgc aatccagaac
    78001 aaataaattt tgtcattcca gctaagtaga ttgtttggtt aggtaataaa ttttggaaag
    78061 gaggaatgat cgtatgttga tagtaagttg ttaaaaatga atggatatca tcttcaataa
    78121 cccatagacc ttctttttca atcacttcgg ctaattgctc tcgtcttttg tgagagattt
    78181 gaaaccctat aggattatta caagaaggca taagaaagac accatgaatc ttcttttttc
    78241 tacattcctg aatcaatata tcaggtcgca ttccttgctc gtcaaaatca attggaacga
    78301 tctctaaatg atataactga gccaattcaa tgaaattagc gtatgtatat cggtctgttg
    78361 ctattctatc acctggagag aaaagtgcag aaagtgtgat agccaatcca ttttgaacac
    78421 cggaaacaat agatagagat tctaaggacg gaatgactcc ttgagttttt aaccaatttg
    78481 ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg gtaattaagc aaaccaacaa
    78541 gatttgggtt attactagtt gattgaataa acgggacaac gaatttatta cattcttcaa
    78601 aagaactaac cagaccaaaa tcaatgatat gttcggttac ttcattggta gagatggtga
    78661 tggactcaaa gacattggga gaaataaatg tgccacttcc aatattcgta tacagcaaac
    78721 ctttctcaat tccatattta taagccttgc caacggtagt aaaatttaaa tctaaataat
    78781 cagctagctc tctttgggag ggtaactgag tgtttttctg taatttattc tttaaaatat
    78841 cttgttctaa ttgttgaatc aacgatcgat aataaggacg cttcaatttt tgtttgtctg
    78901 gtcgccaagt taacgggtaa ttgtcataag aattaatagg cattttctcc actccttaaa
    78961 attgtatacc atacaatttt accattgatt gtattgattt tagaagttaa tcttttgtga
    79021 ggagggaatt gtctatgaaa attattaatt ttgaggaagt agtagcttct tttagttttg
    79081 aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta tgaaagtggt aaaatcagcc
    79141 aaaatcctcg attggtggaa attttacctg acggaaaagg caaaaatatg tttgcgatga
    79201 tgcctgctta tttgggggag aacagatatt ttggcacaaa agtcattacc gcttttccgg
    79261 ataatcatca gtatcattta ccttctcatt taggagagat tttcttgttt gatgctcaaa
    79321 acggactacc caaagcattg ataaacgcaa atgcagtcac ctggattcga acagctgctg
    79381 tatctgcgct ggcaacagat tacttagcaa atccgcatgc agaaacactt gctttaattg
    79441 gagctggtca acaagcattg tcgcatttga ctgcgatttc taccattcgt cccatcacta
    79501 cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac ttttatcgct aaagctaaaa
    79561 aacagtatcc taaaataacg tttataaatg caatatcagt agaagatgca gtacgtccag
    79621 cggaaatcat ttgtacgttg acctctagta aagaggcatt tcttcaaaaa gagtgggtaa
    79681 gggaagacgc acatatcaat gctgtgggca catttactcc tgatacaaga gagataagta
    79741 catcgttgat ggaaacttct caaatctatg tagatgatta ctcagctgcc ttaacagaaa
    79801 gcggggacct gcttatagcc atggcagaag gagatttaga ggaatcttgt attgttggta
    79861 cattaggcga attagtttct gagaaaaaaa cattttataa aggagaatcg aggccgacga
    79921 ttttcgacgc agttggtcta gctattgaag atctttgttg tgcagaatat atttataaca
    79981 aattagagaa aggggcttta aaatgaactt agattattac gtagttgatg catttgcaga
    80041 tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta gaagaatggc tgccagaagg
    80101 tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa acagcattta cagtgaagaa
    80161 aaaccaagaa tttgagctta gatggtttac gccagatcga gaaatcgatc tttgtggtca
    80221 cgcgacatta gcaacagcat ttgttttatt taactattac aaaatacctg atgaaacgat
    80281 taaattttct actcaaagcg gtaatctatt tgtgacaaga attaaagatt attattacat
    80341 ggattttcct agtattatgc cgaaaaaagt gccgatattg tctgaatatg aagaagcgat
    80401 tggggctaag attaaagaag cctacttagc acgtgattta tttttcgtat tagaagatga
    80461 aaaaacggtg gctaaattgc agccagattt tacagctatc aaaaattttg aattaggaat
    80521 aggagtcatc gtgacagcag aaagtgtgca aaaagacttt gtttctagaa ccttctttcc
    80581 aaaattaaca atcaatgaag atccagtatg tggatcagca cattctaatc ttattcctta
    80641 ttgggcagaa agaatgaata aaacaaaatt gtcagcttat caaatgtcat caaggggcgg
    80701 ggatctagaa tgtgaattaa aagaagatcg tgtgataata ggaggaaaag cagttttgtt
    80761 ttctaaaggt acctcgttta tttgatttct ttcaaatgaa ttaaaaataa attggtggag
    80821 agtggcaacc ttatagctac aatggttgtt aaaaaaagac gcaaactttt tcaatttaat
    80881 gaaaagtttg cgtctcattt taattattgg tgtttgtttt ttattcaatc aagagtaaaa
    80941 tgccccatac taactatcct cggatgactt cgattttata accatcaggg tcaatgacaa
    81001 agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc agtaatctca agaccggcag
    81061 ctttatgttg ctcgtgtaat ttttctagat catcagctgc tatagcgata tgaccatagc
    81121 cgtctcctag atcatacgca ccatgatcat agttgtaagt caactctaat tcatagtcat
    81181 ccccaggaag tgtcaaataa acaagtgtaa atttgttttc tggaaaatca cggcggcggc
    81241 tttcttcaaa accaaatgcc ttttgataaa attcgattga tgcttcaaga tctttcactc
    81301 gaacacatgt gtgagccatt ttcatagatt catctctcct tttcctttta ctcaatcata
    81361 acaaaaagaa gtaaggaaat agttgatttg tgcttgttca tgagaaattt ctcatgtaaa
    81421 atggatagaa aataaaactg ttaaggtgga aactattcat ggataaacca atttttggtg
    81481 aaaaaaagca atttgctgat tatcaaaccc gttatgcagc atatattgtc atagaaagag
    81541 atcagcagat tgcagtaatc gaggctccaa atggtgcttt ttttcttcct ggcggggaaa
    81601 ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga gctgatagaa gaaatgggaa
    81661 ttgtggcaga aatttcttct tatctgggag aagctgatga gtatttttac tcgaattatc
    81721 gtgcaactta ttattataat ccaggatatt tctttgttgc tgattcttgg aagcgtatag
    81781 gagaaccaac tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa gcgcttgtga
    81841 aattgaaacg tggtagccac cgatgggcag tcgagagatg gatcgaaaaa aataaaaact
    81901 gaaagaaagc gagtagatca gctttctctc agttttttta tttattacag tacatatttt
    81961 ttgattgctt cagctacacc gtgctcgtcg tttgatgaag tgatgacatt tgctgcttct
    82021 ttgacaagag aaacggcatt tcccattgct actcctagac cagcatattc aatcatggat
    82081 aagtcgttct cgttatctcc gatagccatg atttcatctt gatcaatacc aaggtgctgt
    82141 gcgagattcg caactgccgc acctttactt gcttctttat ttagtacttc gaagtaatag
    82201 ggcgcacttt tgaccgttgt gtatttatca cggaaagttt gcggtaaacg cgcaattgct
    82261 gcatctaaaa tttctggttc gtcgatcatc atcattttga cgatgttcat gtctggtgtc
    82321 atttcttcag gtgttcgata ttttagcggc atcttgacta aacttgcttc gtggatcgta
    82381 taagcgctga tatctcgatt aggcgtgtag atcgctttgt catcgatcga atggagatga
    82441 ctgccgacac ggcgtgccat cacttcgatc tctaggaaat cttcatgtgt cagtccgtga
    82501 cgggcgatga ttttacctga tttcgtttgt tgtacgagtg ccccgttata agtaataacg
    82561 taatcattat cttgaaaaag gttcaactcg tttaactgtt cctggacacc tggtaaggga
    82621 cggccagtgc ataaaacgat cgaaacacct tttgcaacag cagcggcaat cgcttctttt
    82681 acttcttttg ttacttctct tttctcattt aataaagtac catcgatgtc gatagcgact
    82741 agtttgatag acataatttc ctccaatata ttttaattta tttcaatcaa tgcgccatta
    82801 cggatatggc tggcaaattc ttgataagtt tcgtcaaata aatcataatg atcacgcaag
    82861 gacggatcaa ccatttcttt tggaaagaaa aatcgctcat ctccttgttc ttgtcccgct
    82921 aatgcagcaa caagctgact aacctgtgat aattctatca aagttccgtc atttcgcaaa
    82981 atctcgattt gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata aggtagatcg
    83041 tagctagaat tcacagcagt gtaataaaca ggattatatc cgaccttttc tactaacaaa
    83101 gtgagttctt ggactaattt tgaatcccgg ttgccagaaa aagtagcaga tttcagtggt
    83161 ttacgattca aaaaacgttt agctaaatca tttaaaatag gatcagcaga ttcagaccat
    83221 tgagtaaagt aagtgcccaa gaccccatca tcaagtttga ggtattcttc taaagtaaag
    83281 cttccgtcaa gaaatggcag aagtaattga gaatggagtt caaaactgct ggcatcttct
    83341 tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa ttacttccat accacgggaa
    83401 acaggatgga agtacacttg cacatacatt tgatatcggc taacgatata atcttccact
    83461 gcatgcatgc cactcatgga aaaagcgatc ccgccttcat aaggacgaat cacacgtaat
    83521 attcgggtaa gatcaaatgt tccatattct gttccagtga aataagcatc ccgaagcaaa
    83581 tagtccattc gatctgcatc gatctgacta gaaatcattt ggacaacttg tgggttgggg
    83641 taagtttttt ggatcacact agctaccttt tcaggaaaac cttcttctac tcggttaaga
    83701 atctgataca cttctgtttc tggagaagtg atgatctcta cagtgatggc ttcatgattc
    83761 gtatggaaga tatgttcaaa tgtatgagag taaggaccat gaccgacatc atgcaacagt
    83821 gccgcacata aagtcaccag ccgttcctga tcatcccagc ctccgttgcc tattttttct
    83881 tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg aaatctcata aacgcctaat
    83941 gaatgagtaa aacggctatg ttctgctccg tgaaaagtga aagaagaagt gcctaattgt
    84001 ttaatgcgtc gtagacgttg gacttctttc gaattgatca aatctaagat tacttgatgc
    84061 tggacatgga tatagttatg gactggatca cgaaaaactt tttccatagg cagcatttga
    84121 tatttataag gggttgtcat aatgtagctc ctttatgtta ttacgttgtt ccattctctg
    84181 gatttggttg ttccattgct ccagctggat ttcttttttt agccagtcgg tagaatcctg
    84241 taaatcactt gcagaataca gcttttcaaa agcttttgca aatgcttctt tgacttcttt
    84301 tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc attgtagcag gatccactgc
    84361 aggatagcca tttgtaccaa agtcttcttt taaagcagat tgataaaatc gcttcatgac
    84421 ttgcccgcgt ttttcctgat taccgttgac acttaagtac atcataacag aaatcccatt
    84481 tttgatccga cgctgagcga taccggcaaa ttttttgcca tggatgctta aatcataagt
    84541 tccaggacaa taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg gaaaagcgta
    84601 tttagtcaat aggagcattt gctcgtaagc gtcatctatg gttatttttt ttgtgtcact
    84661 ttgggggaaa atcaaagaaa tattcaaaat tccttcatct gatacgatcc ctaatccacc
    84721 tgaatttctg atcactggag cgtaacctgc atctttcagt gtttggatcc cgtcacttag
    84781 aaaaggagtt cgaacatcct tcatacctaa gatgactgtg cagtcatatt gccagaaatg
    84841 taaaaagatt tgctggtgtt ctttagaata ttccgttaat atatctgtta atgcaaaagg
    84901 ggaaaagtcg tttttttgat aaatgtgctg atctagtcga atcgcagggt tcattcaacc
    84961 ggctcctttg tataaattca tattttctac aatattatac tctaaaatca aagagttgtt
    85021 ttggaaaaaa ggttttctgt aaaaatggac aagttggttg acaaaacaaa agaaactagg
    85081 aacaatgtag ctatgagaag taaaggagaa tgaataatgg aattatcaca aggaacaccg
    85141 atttcaatca aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga tttttatttt
    85201 gatttgaaag ggcaaatggt gacaattggc gatacgctgt acatacgtta taaagagatt
    85261 caggaggaga cgggcgatga gattcctgta acgatcaaat tagttccaga tggtcatgta
    85321 cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat ttggctataa agaacggtta
    85381 gaaacatcct atcgaacacc atacggtatg atccagattg ctacttttac gaaagaactg
    85441 catgttagtt tgaaagaccg tcccacagga gggaaggttc gaatcgatta tgatctgttc
    85501 atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg attttacagc gtaaatataa
    85561 aagaaaagtt tgattttttg tgtctgattt tgtatgataa ggagtagact gtgaaaggac
    85621 gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt atcaatgatc
    85681 gaagtagcac acgcgatctt agaacaacgt ggcgatgtca tggatttttc tgatttagct
    85741 aaccagatcc aaaactatct tgggaaatca gacagtgaaa ttcgtgattc actcgcacaa
    85801 ttttatactg acttgaatat tgacggcagc tttatctcat taggggataa tcgttggggc
    85861 ttgcgttcat ggtatgctat cgattcgatc gatgaagaag taaaccatgg aatggacgaa
    85921 gaggatgaag atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt tatcaatgat
    85981 gatgaagacg cgatcgatta caatgacgat gacccagaag atacagatct gacagaagaa
    86041 gatgacgatg atctgtttga tgacgatgat gatgaagatg aagaaatcgc tgcttataat
    86101 tctgacttgc aagaaatcgg agcagatgac ccgacagatg atgaagaaga cttgccagga
    86161 aatatcgaag aagatttaag tatcatagac gaagacgatg atgatgaaga ttatgaagag
    86221 gaagaatttt ctgactctga aaaagaataa acattatttt cttacgagag gttgtgacag
    86281 agacgatcag cctatcagaa taaggaggtg tgacacgat
//
LOCUS       DACGDM010000004        81849 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.004, whole genome shotgun sequence.
ACCESSION   DACGDM010000004 DACGDM010000000
VERSION     DACGDM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 81849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.004"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            52..570
                     /locus_tag="IXR05_000293"
     CDS             52..570
                     /locus_tag="IXR05_000293"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4258843.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            698..1381
                     /locus_tag="IXR05_000294"
     CDS             698..1381
                     /locus_tag="IXR05_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAQ4258844.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1690..1763
                     /locus_tag="IXR05_000295"
     tRNA            1690..1763
                     /locus_tag="IXR05_000295"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1724..1726,aa:Arg,seq:tct)
     gene            1922..2281
                     /locus_tag="IXR05_000296"
     CDS             1922..2281
                     /locus_tag="IXR05_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAQ4258845.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2404..4035
                     /locus_tag="IXR05_000297"
     CDS             2404..4035
                     /locus_tag="IXR05_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAQ4258846.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4097..4738)
                     /locus_tag="IXR05_000298"
     CDS             complement(4097..4738)
                     /locus_tag="IXR05_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4258847.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            5020..5328
                     /gene="rplU"
                     /locus_tag="IXR05_000299"
     CDS             5020..5328
                     /gene="rplU"
                     /locus_tag="IXR05_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAQ4258848.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5355..5699
                     /locus_tag="IXR05_000300"
     CDS             5355..5699
                     /locus_tag="IXR05_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAQ4258849.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5712..6005
                     /gene="rpmA"
                     /locus_tag="IXR05_000301"
     CDS             5712..6005
                     /gene="rpmA"
                     /locus_tag="IXR05_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAQ4258850.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6412..9246
                     /locus_tag="IXR05_000302"
     CDS             6412..9246
                     /locus_tag="IXR05_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4258851.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            9437..9928
                     /locus_tag="IXR05_000303"
     CDS             9437..9928
                     /locus_tag="IXR05_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAQ4258852.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10031..11020
                     /gene="manX"
                     /locus_tag="IXR05_000304"
     CDS             10031..11020
                     /gene="manX"
                     /locus_tag="IXR05_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAQ4258853.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11053..11856
                     /locus_tag="IXR05_000305"
     CDS             11053..11856
                     /locus_tag="IXR05_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAQ4258854.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11877..12791
                     /locus_tag="IXR05_000306"
     CDS             11877..12791
                     /locus_tag="IXR05_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAQ4258855.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12874..13248
                     /locus_tag="IXR05_000307"
     CDS             12874..13248
                     /locus_tag="IXR05_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAQ4258856.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13387..13632
                     /locus_tag="IXR05_000308"
     CDS             13387..13632
                     /locus_tag="IXR05_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4258857.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13804..14868
                     /locus_tag="IXR05_000309"
     CDS             13804..14868
                     /locus_tag="IXR05_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4258858.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15114..15539
                     /locus_tag="IXR05_000310"
     CDS             15114..15539
                     /locus_tag="IXR05_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4258859.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15532..15981
                     /gene="nusB"
                     /locus_tag="IXR05_000311"
     CDS             15532..15981
                     /gene="nusB"
                     /locus_tag="IXR05_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAQ4258860.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16078..16932
                     /locus_tag="IXR05_000312"
     CDS             16078..16932
                     /locus_tag="IXR05_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAQ4258861.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16933..18270
                     /locus_tag="IXR05_000313"
     CDS             16933..18270
                     /locus_tag="IXR05_000313"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAQ4258862.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18275..18499
                     /locus_tag="IXR05_000314"
     CDS             18275..18499
                     /locus_tag="IXR05_000314"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAQ4258863.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18501..19391
                     /locus_tag="IXR05_000315"
     CDS             18501..19391
                     /locus_tag="IXR05_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4258864.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19400..20218
                     /locus_tag="IXR05_000316"
     CDS             19400..20218
                     /locus_tag="IXR05_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAQ4258865.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20325..20774
                     /locus_tag="IXR05_000317"
     CDS             20325..20774
                     /locus_tag="IXR05_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4258866.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20792..22474
                     /gene="recN"
                     /locus_tag="IXR05_000318"
     CDS             20792..22474
                     /gene="recN"
                     /locus_tag="IXR05_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAQ4258867.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22529..22645)
                     /locus_tag="IXR05_000319"
     CDS             complement(22529..22645)
                     /locus_tag="IXR05_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAQ4258868.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22718..23674)
                     /locus_tag="IXR05_000320"
     CDS             complement(22718..23674)
                     /locus_tag="IXR05_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4258869.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23845..24213
                     /locus_tag="IXR05_000321"
     CDS             23845..24213
                     /locus_tag="IXR05_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAQ4258870.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24383..24814
                     /gene="mraZ"
                     /locus_tag="IXR05_000322"
     CDS             24383..24814
                     /gene="mraZ"
                     /locus_tag="IXR05_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAQ4258871.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24835..25794
                     /gene="rsmH"
                     /locus_tag="IXR05_000323"
     CDS             24835..25794
                     /gene="rsmH"
                     /locus_tag="IXR05_000323"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAQ4258872.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25799..26200
                     /gene="ftsL"
                     /locus_tag="IXR05_000324"
     CDS             25799..26200
                     /gene="ftsL"
                     /locus_tag="IXR05_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAQ4258873.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26201..28393
                     /locus_tag="IXR05_000325"
     CDS             26201..28393
                     /locus_tag="IXR05_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4258874.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28419..29381
                     /locus_tag="IXR05_000326"
     CDS             28419..29381
                     /locus_tag="IXR05_000326"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAQ4258875.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29395..30756
                     /locus_tag="IXR05_000327"
     CDS             29395..30756
                     /locus_tag="IXR05_000327"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAQ4258876.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30782..31870
                     /gene="murG"
                     /locus_tag="IXR05_000328"
     CDS             30782..31870
                     /gene="murG"
                     /locus_tag="IXR05_000328"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAQ4258877.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31885..33105
                     /locus_tag="IXR05_000329"
     CDS             31885..33105
                     /locus_tag="IXR05_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAQ4258878.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33261..34586
                     /gene="ftsA"
                     /locus_tag="IXR05_000330"
     CDS             33261..34586
                     /gene="ftsA"
                     /locus_tag="IXR05_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAQ4258879.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34609..35850
                     /gene="ftsZ"
                     /locus_tag="IXR05_000331"
     CDS             34609..35850
                     /gene="ftsZ"
                     /locus_tag="IXR05_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAQ4258880.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35867..36544
                     /locus_tag="IXR05_000332"
     CDS             35867..36544
                     /locus_tag="IXR05_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAQ4258881.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36558..37157
                     /locus_tag="IXR05_000333"
     CDS             36558..37157
                     /locus_tag="IXR05_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAQ4258882.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37172..37459
                     /locus_tag="IXR05_000334"
     CDS             37172..37459
                     /locus_tag="IXR05_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAQ4258883.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37508..38290
                     /locus_tag="IXR05_000335"
     CDS             37508..38290
                     /locus_tag="IXR05_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAQ4258884.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38311..39018
                     /locus_tag="IXR05_000336"
     CDS             38311..39018
                     /locus_tag="IXR05_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAQ4258885.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39280..42078
                     /gene="ileS"
                     /locus_tag="IXR05_000337"
     CDS             39280..42078
                     /gene="ileS"
                     /locus_tag="IXR05_000337"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAQ4258886.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42127..43653)
                     /locus_tag="IXR05_000338"
     CDS             complement(42127..43653)
                     /locus_tag="IXR05_000338"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAQ4258887.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43668..44315)
                     /locus_tag="IXR05_000339"
     CDS             complement(43668..44315)
                     /locus_tag="IXR05_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAQ4258888.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44499..44828)
                     /locus_tag="IXR05_000340"
     CDS             complement(44499..44828)
                     /locus_tag="IXR05_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAQ4258889.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45005..45733
                     /gene="sfsA"
                     /locus_tag="IXR05_000341"
     CDS             45005..45733
                     /gene="sfsA"
                     /locus_tag="IXR05_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAQ4258890.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45749..46762
                     /locus_tag="IXR05_000342"
     CDS             45749..46762
                     /locus_tag="IXR05_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4258891.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46762..48039
                     /locus_tag="IXR05_000343"
     CDS             46762..48039
                     /locus_tag="IXR05_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4258892.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48102..50804
                     /locus_tag="IXR05_000344"
     CDS             48102..50804
                     /locus_tag="IXR05_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4258893.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50956..51273
                     /locus_tag="IXR05_000345"
     CDS             50956..51273
                     /locus_tag="IXR05_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4258894.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51303..51623
                     /locus_tag="IXR05_000346"
     CDS             51303..51623
                     /locus_tag="IXR05_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4258895.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51731..53191
                     /locus_tag="IXR05_000347"
     CDS             51731..53191
                     /locus_tag="IXR05_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4258896.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53259..53480
                     /locus_tag="IXR05_000348"
     CDS             53259..53480
                     /locus_tag="IXR05_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258897.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53511..53693
                     /locus_tag="IXR05_000349"
     CDS             53511..53693
                     /locus_tag="IXR05_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAQ4258898.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53693..54106
                     /locus_tag="IXR05_000350"
     CDS             53693..54106
                     /locus_tag="IXR05_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAQ4258899.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54229..55410
                     /locus_tag="IXR05_000351"
     CDS             54229..55410
                     /locus_tag="IXR05_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4258900.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            55799..55872
                     /locus_tag="IXR05_000352"
     tRNA            55799..55872
                     /locus_tag="IXR05_000352"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55833..55835,aa:Arg,seq:cct)
     gene            complement(55909..56109)
                     /locus_tag="IXR05_000353"
     CDS             complement(55909..56109)
                     /locus_tag="IXR05_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4258901.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(56414..57646)
                     /locus_tag="IXR05_000354"
     CDS             complement(56414..57646)
                     /locus_tag="IXR05_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4258902.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            57900..58469
                     /locus_tag="IXR05_000355"
     CDS             57900..58469
                     /locus_tag="IXR05_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4258903.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(58647..59087)
                     /locus_tag="IXR05_000356"
     CDS             complement(58647..59087)
                     /locus_tag="IXR05_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAQ4258904.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            59245..60009
                     /gene="map"
                     /locus_tag="IXR05_000357"
     CDS             59245..60009
                     /gene="map"
                     /locus_tag="IXR05_000357"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAQ4258905.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            60041..60964
                     /locus_tag="IXR05_000358"
     CDS             60041..60964
                     /locus_tag="IXR05_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAQ4258906.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            61040..62179
                     /locus_tag="IXR05_000359"
     CDS             61040..62179
                     /locus_tag="IXR05_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAQ4258907.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIVLIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            62172..62972
                     /locus_tag="IXR05_000360"
     CDS             62172..62972
                     /locus_tag="IXR05_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4258908.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            62972..63799
                     /locus_tag="IXR05_000361"
     CDS             62972..63799
                     /locus_tag="IXR05_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4258909.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            63777..64511
                     /locus_tag="IXR05_000362"
     CDS             63777..64511
                     /locus_tag="IXR05_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4258910.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            64611..65477
                     /gene="rfbA"
                     /locus_tag="IXR05_000363"
     CDS             64611..65477
                     /gene="rfbA"
                     /locus_tag="IXR05_000363"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAQ4258911.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            65491..66063
                     /gene="rfbC"
                     /locus_tag="IXR05_000364"
     CDS             65491..66063
                     /gene="rfbC"
                     /locus_tag="IXR05_000364"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAQ4258912.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            66085..67113
                     /gene="rfbB"
                     /locus_tag="IXR05_000365"
     CDS             66085..67113
                     /gene="rfbB"
                     /locus_tag="IXR05_000365"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAQ4258913.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            67211..68062
                     /gene="rfbD"
                     /locus_tag="IXR05_000366"
     CDS             67211..68062
                     /gene="rfbD"
                     /locus_tag="IXR05_000366"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAQ4258914.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            68097..70130
                     /locus_tag="IXR05_000367"
     CDS             68097..70130
                     /locus_tag="IXR05_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258915.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            70174..71454
                     /locus_tag="IXR05_000368"
     CDS             70174..71454
                     /locus_tag="IXR05_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAQ4258916.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LVILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTDREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            71664..72470
                     /locus_tag="IXR05_000369"
     CDS             71664..72470
                     /locus_tag="IXR05_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4258917.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            72482..73702
                     /locus_tag="IXR05_000370"
     CDS             72482..73702
                     /locus_tag="IXR05_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258918.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            73692..75278
                     /locus_tag="IXR05_000371"
     CDS             73692..75278
                     /locus_tag="IXR05_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4258919.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            75317..77455
                     /locus_tag="IXR05_000372"
     CDS             75317..77455
                     /locus_tag="IXR05_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4258920.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKDGIGDFSLRPD"
     gene            complement(77823..78806)
                     /locus_tag="IXR05_000373"
     CDS             complement(77823..78806)
                     /locus_tag="IXR05_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAQ4258921.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            79184..80575
                     /locus_tag="IXR05_000374"
     CDS             79184..80575
                     /locus_tag="IXR05_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4258922.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERSFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            80591..81631
                     /locus_tag="IXR05_000375"
     CDS             80591..81631
                     /locus_tag="IXR05_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4258923.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            81650..>81849
                     /locus_tag="IXR05_000376"
     CDS             81650..>81849
                     /locus_tag="IXR05_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAQ4258924.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPK"
BASE COUNT        26706 a        13832 c        17352 g        23959 t
ORIGIN      
        1 atcgttatta tatgattaag aaggattgaa taaagaaaga agttgaaaac gatacctgat
       61 tacaaaaaaa taacttttat aagttctata acgttgatta tatttttaat tcttattctt
      121 ctcgtcgtct tggttccccg aatttttggt ttgactcctt atattattga ggacaaagaa
      181 atgagtccat attatgcaca aggaaatctg atatatgtac gaccgaaaaa tacaaatgag
      241 attttagtcg gagatattat tacatattat gaaaattcag gaaaaaaaat ctcgacgcgt
      301 cgcgtaatag ccgttgaaaa caaccacgaa gatttttata caaaagctga tacaaagact
      361 tatattgagc ctggagtagt aaaaaagaga aatattatcg gtagtcccat ctttcagatt
      421 ccatatattg gactagtcct ttcaaaaacg gcatttgcat ggattcaggg gttattcttt
      481 acgattgctt tttgcctaac aggaatcaca gcatggaata cctttgtaga gttgaaaaag
      541 aagcggagac gaacacagaa atttttgtaa gaatgttaaa aacataaatg tattccagag
      601 atccaacgac tcttctgaac atgaaacacg agaaaacact catgcagctt gtagatttag
      661 tcagttgttc gtataatgtg tgaagaggag gagtagtatg cgcaatgaaa tgatgcatcg
      721 tcctgtagtc aaagaagaac tattggattt tatgcgtacc cagcaaaaaa aattaccggg
      781 tgagctaggc aaactggaag aagaagctca tgtagcagaa gtaccagtta ttccccatga
      841 aacagttgta tttttgaaat ttttacttgg acagcttcag cctgaacgaa tcttggagat
      901 cggagcagct atcggttttt catcaagtgt catggccacg acaatcggag aaaacgctca
      961 tgttacgaca attgatcgtt tcgatgtcat gatcgagaaa gctaaaaaaa actatgaacg
     1021 tctaggactg acagataaag tgactttgct tgaaggtcaa gcagcagata tcttgccgga
     1081 gttgtctggt ccgtatgact ttatttttat ggatagtgca aaatcaaaat atattgaatt
     1141 tttacctgaa tgcttacgtt tgttaagaaa aggtggcgtt ttgatggtag atgacatctt
     1201 ccaaggagga acgatcttgc tcccagatga agagattccc cgtggcaaac gagctatcca
     1261 tcgtaaatta aatgaatttc ttcgtgttgt gatggatcat cccgatttga catcgacaat
     1321 cttgccatta ggtgatggtg tgatcttaat gacaaaggaa tcagaaacaa tcgagttgtg
     1381 atacatgatt atggcagcct gtagataatc gattgaatcg agggctcaat tcgaacttga
     1441 tgtaaaagtt tctatatttg taagtcaatt aaaggataca ggaaatctaa ataaacagga
     1501 gtagcatgaa gtcaatgtag ctcctgtttt caattgataa ccttagaaca gctgaaggag
     1561 aatgtctcgt tttaaaagat tgatttagta gttgggccaa aataattcat tatttgctaa
     1621 ttaaataact atttcgtatt gacagaagca atttaattat ctataattat tgatgttccg
     1681 ctgattcttg tcatagtagc tcagctggat agagcatccg ccttctaagc ggacggtcgg
     1741 gggttcgaat ccctcctgtg acgctaaaaa accgttagaa actgaggttt ctaacggttt
     1801 ttctttgttt tttgtgccaa tattgtttgt tttcaaaggc aaataaaata aaaaaacatc
     1861 cttatcgagt acaattataa ggagcaaaaa aataaaactc atcagaaaag aggaagaaga
     1921 tatgacgata ctatctagaa ttttagtgac tctagttgca attgaatttt tttatatcat
     1981 gtatatcgaa acggtgagaa ctgattctga cacgacaagt agggttttta aaatgagtaa
     2041 agaagagtta agcagaaaat ctgttcaaac attgtttaag aaccaaggag tgtacaatgg
     2101 actattagga gtgggactac tttatggagc ttatctttct tccgcatcta aagaaatcac
     2161 aagtatgcta ttaatatcta ttttttttgt tgcattatat ggcagtttga ctagcgatcg
     2221 ttggatttta ctcaaacaag gtgggctagc tctgttggca ttgctttcta ttttcttata
     2281 aatatagaaa aaataagaat ttatctaaca ggaaactttg tgaaaaatat tactttatct
     2341 catgaaatat gatattctaa tgaatggtat tttagaaaat ttcatgaaaa aggagttaga
     2401 taggtgttca aaaattatgt ttcctcacta aaaaaagaat tttcaggtta tgatctttca
     2461 agatttcaga aagatctttt ggctgggatc acagtagctg ctgtagcatt gcctttagcc
     2521 ttggcttttg gggtatcaag cggagctgat gcggccgcag gtttgattac ggctatcatt
     2581 gccggtatcg ttattggcgg tttatcaggc ggtttttatc aaatatcagg tccgacaggt
     2641 gcgatggcag ctatcttgat gtctattgcg gcaacaaagg gaatgcaagg tgtattgctt
     2701 gctacttttt tagcgggtct atttttactt gcagcaggac ttttccgatt aggaacactg
     2761 acttctttta tcccagcacc cgtaattacg gggtttactt caggtattgc tatcattatt
     2821 gcattaggtc agatcgataa tttatttggt gttcactcgg aaggtacaaa cgttattgaa
     2881 aaactaagta gttatcaaac gataggattt ccgataaaca cagcctcttt gatcatggga
     2941 gggctagtca ttttagggat gtttatctat ccaaaaaaat gggcgaaacg aatgcctagt
     3001 tcgctgctgg ctatcatttt ggcaacagca gttatgctat tgttccattt accagtagca
     3061 actgtgggta agattccaca aacattgatc agtagtaatc gtttgaatat gggagatttt
     3121 agcttttctg ccttgcaaca agtggcagtt ccagctatta gcattgcttt attaggaatg
     3181 attgaaagct tgctatgtgg tgcttcggct ggccgaatgg caaataagcc cttagatagc
     3241 aatcaagaat taatggcgca aggaattgga aatctgttgc ttcctttctt tggcgggatt
     3301 cctgctactg cggccatcgc ccgtacaagc gtggccatca aatctggtgc acaaactaga
     3361 ttagctggta tgatacatgc agttgtctta ctgctctcca tgcttgtttt tgcgccagtg
     3421 atgtcacaga ttccaatgcc agcacttgca ggtgttttga ttgtgacggc ttggcgtatg
     3481 aatgaatggg aaacgatcaa ggagctattt actaataaat attggtcagc agttctattg
     3541 tttatcctta cgatgatttg tacagttatc tttgatttaa gtattgctat cgtgatcggg
     3601 gtgatcggcg gctgtgtatt ttttgttgtc aaaagcgctg ctatcacgat ttcattagaa
     3661 acgatcgatt ggcaaagaat ggggctgcca gaaacggaaa agctgaataa ctggacagta
     3721 gtgtatatta gtggtccact gttttttatg tcttcagaaa aactcaaaaa taaattggaa
     3781 gaactaaatc atcacgatgg tgtcattttc tccatgcgag gcgtaccaag tattgatttg
     3841 acggcacgtg cagtttttga tgaatttcaa gaaaaagcag agcaaagagg acaaacgatt
     3901 atctatactt ccttgcagcc agaagtagaa aaacaacttt ctcacttgtg ggaacataca
     3961 ttcacgcatc aacatcaaac agttgctcat gcgttgacag ctttacatgc gaaatatact
     4021 gcaattagcc attaaaacaa tgaaaaagaa cagacaagac tgtaaactga agattttatg
     4081 gtcttgtctg ttctttttaa tattgctgta aaagtgaagc tagtacttgc cagtcttgat
     4141 ggataacagg tacaagggag cgattgtaga aaatagctgc tggatgaaaa agtggaagaa
     4201 ttcgatagtt tttttctgac cattcgtagg catccttttg ttctgttaat tgtaagacag
     4261 gccctgtata gagttgacca tgatttttgg taaccgtata ttctttgcca agtaaacgtt
     4321 gaagaccaat gtttccaagt gtcgcaatta attttggctg gaccttcatc agttcgtaat
     4381 ccaatattgg tgcatgcgca aatacttcgg aacgagtagg tgtccgattt ggataaacag
     4441 tttctgactg ttgtgtccgt ttattgatcc gatgagtcac gcgatacggg cggctcctta
     4501 cagcactggt gatatacacc tcttctcgtg ttaagccagt tgaagaaagt gcctgcatca
     4561 attcttttcc agcttgaccg ctaaaaggaa catgcgtatc aatctctgtt ttccctgggg
     4621 cttctcccac gagcatcagt ttaggatgaa gaggtccttg cccagcgata aatccttcta
     4681 caggacggcc gttcattctt aaagaagctt cttgtatcag ttcttttggg tattccattt
     4741 atgctcctcc tttttctttt attataagaa taaaagaaac acaatgcgac tattttattt
     4801 ggtagaactg tgaggataga aaagcagaag tattgcttga atttttgttt tactttttga
     4861 ttttaaattt agttgactaa cggttgctgt tctggtaagc tagtactgtt gtaattgtgg
     4921 actccacagc tacaaccgct cagaacaagt aataagcaca gcatatgctg tcacttcgga
     4981 tggcgagtct aagtatatca gaaggaggtg ctttatagca tgtacgcaat tattaaaact
     5041 ggtggtaaac aagtaaaagt tgaagtggga caagcaatct atgttgaaaa acttgacgtt
     5101 gaagcaggag aaaaagttgt ttttgacgaa gttatcttag taggcggaga atctacaaaa
     5161 gtaggcgctc caactgttgc aggtgcaact gttgaaggta ctgttgaaaa acacggcaaa
     5221 caaaagaaag tcgttacttt caaatacaaa cctaaaaaac attcacaccg taaacaaggt
     5281 catcgtcaac catatacaaa agtggttatc gacgcgatca acgcttaata gcgtttgaga
     5341 aagaaggcct atatatgatc aaaggaacat ttaagcgaaa tgacgcaggt cagatcgttt
     5401 cattcacttt gaccgggcat gctgatgctg gtccttatgg aagtgatatc gtttgtgcgg
     5461 gtgtttctgc gttagcgatc agcactgtca acgggattgc ctcattagcc ggttttgagc
     5521 cgattgttga aatgaatgaa gaagaaggcg gttatcttta taccgaagtc acttcaggaa
     5581 tgacacaaga acaaaacaat attgctgaga ttctattaga aaatctttta ttaggattac
     5641 aatcgataga agctgaaaac tcagaatata tccaaattaa aacaattaat gataaatagg
     5701 aggtgcagac catgttgtta tctatgaatc tacaattatt tgcccacaaa aaaggtggcg
     5761 gttctacatc taacggccgt gactcagaat caaaacgtct aggtgctaaa cgtgctgatg
     5821 gacaaacagt tacaggtgga tcaattcttt accgtcaacg cggtacaaaa atctatccag
     5881 gtgtaaacgt gggtatcggt ggagacgaca ctttatttgc aaaagttgat ggcgtagtac
     5941 gtttcgaacg taaaggccgt aacaaaaaac aagtgtctgt ttatccagta gctcaagaag
     6001 cttaattgaa tcttatgatt aaagaggttg tgacaagact tttgtcacag ccttttttgt
     6061 ttataaaaat aaaagttgta gtggaggcta cgaagtttac tttgtctttt tacacttaat
     6121 atttttttgc caatttggaa tcaggatgtt ttgataacta tcgttttcaa ttgatggaag
     6181 ctatattgtt tgctatcagt gaaataatta tatggtaaac agtgttcttt ttcttgtttc
     6241 cattataaaa atcgtatcgg gatttttcgt tcttttaaat tgaacatttc tatctatccg
     6301 cgtgttatca acaaaacaaa atcaggtaaa tagttgacga aacagaaata aatacatagt
     6361 attatgtttt gaagcctaag tacaatagtc tatagaaaag gagcgatacc attggcaaaa
     6421 cgcattgacc gaatttatat gtatgtcaaa gaaaaaaccg ctcatttaac aaaggcagaa
     6481 tatgatcaag gagtaacaac acaggaaatt gctgaagtgt tagggattca gcgaacaaat
     6541 agcagtaaag atctgaatca gctagtgcgc gaaggaaaac tgataaagac agacggacga
     6601 ccagtacgtt acatatatca aacactcgtt acgcacgtaa agccagttac aaaacatgta
     6661 gtcagttaca aagaaacgcc ggtctctgaa gaaaaaaata cactccaaat agatactaag
     6721 gatatctttg caaaaatcat tggagctaac ggcagcatga aaaattcagt ggaacaggca
     6781 aaagctgcga ttttgtatcc gccaagagga ttaaattgtt tgattacagg acctaccgga
     6841 tcaggaaaga cttattttgc acacgcgatg tatcattttg caaaagcgca tcatgtaata
     6901 gatgaggaaa cggaactgat tgttttcaat tgtgctgatt atgccaataa ccctgagctt
     6961 ttgatgagtc atttatttgg gtacgcaaaa ggtgctttta caggcgcaga tgaagaaaaa
     7021 atggggatta tcgatcaagc ggatggcggt atgctgtttt tggatgagat tcaccggttg
     7081 ccgcctgaag gtcaagaaat gatcttttac tttatggatc atggaactta cagtcgtctt
     7141 ggggaaacaa cgaaatccca tgaagcaaat gtacggatcg taggtgcgac cacagaagac
     7201 ccaggttctt ctctattaga aacttttgtt cggcgtatcc caatcaatat caaacttccg
     7261 gcttttgaaa aacgtcctgc aaatgagaaa gtcgatttag taaaaatcat gattgcccac
     7321 gaagcaaacc gcacgcagcg aaagatttct ttgacagaag atgtagcaaa agcattgatc
     7381 ggcagtgtga cctatggaaa tataggacaa ttgaagtcaa atatccagtt agtatgtgca
     7441 cgaggatttc taaatcatat gcaatcaccc gaaatctcga tcacaatcga tgatttgaca
     7501 gaagggattc gtagcggatt gattcaatta gcaagcaacc gcagtgcaat ggcagagctt
     7561 tctaaaatat tggagccaaa gataactgta gcaccaaatg atacgatcat gaaaatccaa
     7621 tcggactcct atgagttacc ttataatcta tatgatatca tcggagataa agcagcttta
     7681 ctgaagtcgg atggtttgga tcaagaagca atcaatcatt tcatttctac agatatcaac
     7741 atccatctga agtctttcta taaagaccat ggtttttctt ttaatgcaga cagcaaatta
     7801 gcagaatttg tagatccgaa aatcatagaa gtgaccaatc agatttatgt aatggtcaaa
     7861 agatctttac catatgagtt tcagcaaaac tttatttatg ctatgagctt gcatatcagt
     7921 tcttttttga aaaaaatcaa cttaggagaa gaacggcata cgaatgataa catccgtgag
     7981 atggcttttg attttccaga tgaatatgct gttgcgaaag aagtgcgtag ttatatcgaa
     8041 acgtattttc aagtggagat tccagaaagt gaagactatt acttgaccgt tctactcgtc
     8101 tcgttacggg caaatcaagc aagcggcaga atcggtgtag tcgttgcagc tcacggaaac
     8161 agcacagcaa gcagtatggt ccaagttgtc caacagttgt tagatgcaga gaacgtacga
     8221 gcagtagaca tgcctttgga tatggatccg aaaacagcat tggaccgaat tgaacgcaat
     8281 gtacaagaag tagatgaagg aagcggggtc atactcttag tagatatggg gtcccttgcg
     8341 tcgtttaatt cgcaaattca aagagacact ggaattccag tacgtactgt tgatatggta
     8401 acaacttctc tagttttgga aactgtacga aaggtctcag tattagggac agatctagat
     8461 atgttgcatg aatcattgaa aaattttcga ggttacgcag aaatatcttc tgtagaatct
     8521 gttcaggaag caaaacctat tcataagaaa aaagctgttt tggctatctg cgcatctggc
     8581 gaaggtacag cacaaagaat caaagaattg atcgaacgag cggtaaacaa gcgtcaagaa
     8641 acagaattag aagttctagc tttgtcgatt gtggaagtga aagaagaact gccagttatc
     8701 caaaaagaat atcagatcat agctactact gggattactg atttgaatat ccaagcccca
     8761 tttattcctt tagaacgttt tattgatcaa aatatcgaag tcattttgga tcagttgctg
     8821 atggaatcag aattggagga aactgaattc atctccctag atgaagagtc agctaaaaat
     8881 acgtgtgttg agtttatctc tgataacttc atctttatta atggtagtaa gttaatcgat
     8941 ccaatgtggc aattttctac acaaatctct cagacgacgg gaatcggcga tgaagaatat
     9001 ggattcaaaa tcaacctagt gatgcacaca gcaggaatga tcgaacgtat tattcggaat
     9061 gaaccattga ctgtggaaga aaacgaattg acaaatacaa cgaatgatcc tctttatagc
     9121 caattggcag cctcagttgt tctgttggaa gatcagataa aagtaaaagt gccgatagaa
     9181 gaaatgtatt atctgctacg tctagtccat aatcagttag ataaaaaaga atacactgtg
     9241 ccatgaatac acaaaaacga tacactttta tagtgtatcg tttttgtgta ttggttaaga
     9301 atcctttaaa ttcaattagt gtatcgtaaa aaagttggca cgctttttgc ttatagtagt
     9361 gtgtgctagg aggtggttgt tcacacagaa atgatagggg tttctgtgaa gtagtgagga
     9421 agaaggagtt ttgcagatgg atattcgatt ggcacgtata gatgatcgtt taatccacgg
     9481 gcaagtcgca acagtttggt cgaagcaaac aggtgttgaa cgtatcattg tgatcagcga
     9541 tgtagtcgct caagataaat tgagaaagtt tctactaaaa gaagctgcac cgccggggat
     9601 cacagcaaat gtaataaccg tgcagaaaat gattcaaatc tatcatagtg gattattatc
     9661 acgagcaaaa gtgatgcttt tattcaccaa tccccaagat gttgaagcgg ttgtccgctg
     9721 cggtgtacag ttgaagtcgt tgaatatcgg cggtatgagt tttactgaag gcaaatcaat
     9781 gattaccaat tttgtttcag taaatcaaca agatattgat tcctttcgtt acttgaacag
     9841 tcaagaagtg gagttagaga ttcgaaaagt acctgctgac aggaaaatcc ttttgatgga
     9901 actactagcg aaaatcaaaa aggtgtagca agaatggttg ttggaaaagg tcaaataatt
     9961 ctgttgtaat ggttagcaat tattaatatt tttgaatttg ttacaacaaa agtaaatagg
    10021 aggtataaat atggtaggga ttatcctagc aagtcatgga caatttgctg aaggaatctt
    10081 acaatccggt tcaatgatct ttggcgaaca agaaaacgtc aaagccgtga ttttgaaacc
    10141 aagtgaaggt ccagatgact tgagagccaa attggaagaa gcggttgctt cttttgataa
    10201 tcaagacgaa gtgttattct tagttgattt atggggcgga acaccgttca atcaatcaaa
    10261 cacattattc gaagagcaca aagataaatg ggcaatcgtc agcggtttga atttaccaat
    10321 gttgattgaa gcctacgcat cacgcttttc aatggaatct gctcatgaaa ttgcagcaca
    10381 catcattgaa acagcaaaag acggtgtaaa agtaaaaccg gaagaattag aaccggcaga
    10441 agcaccgaaa gcagcagttg aagacgcaca acctaaagga gcacttccag aaggaactgt
    10501 ggtcggagac ggaaaaatca aatatgtatt agcacgtgtt gactcacgtc tgttacatgg
    10561 acaagttgcg acagcttgga caaaagcagt gcaaccaaac cgtattatcg ttgtttcaga
    10621 tgcagtatca aaggatgatc tgcgtaagag actaatcgaa caagctgctc ctccaggtgt
    10681 aaaagcaaat gttattccta ttagcaaaat gatcgaagta gcaaaagacc ctcgttttgg
    10741 aaataccaaa gcattgcttt tatttgaaaa tcctgaagac gtattgacag ctgttgaagg
    10801 tggcgtagac atcaaagaat taaatgttgg gtcaatggcg cattcggtcg gtaaagtcgt
    10861 tgtaagtaaa gtattgtcta tgggacaaga agacgttgaa gcgtttgaga agcttgaaca
    10921 aaaaggtgtg aaattcgatg tacgtaaagt acctaatgat tcacgcgata acatggatga
    10981 tattttgaaa aaagcaaaag ctgaattagc aaaagcgtaa taaataatat taaaatttat
    11041 aggaggctta tcatgtctat tatttcaata attttagtcg tattagttgc ctttctagct
    11101 ggtatggaag gtattcttga tgaatttcaa tttcatcaac cactagtggc atgtacattg
    11161 atcggtttag ttaccggtaa cctcgaagct ggtatcgtac ttggcggtac gcttcagatg
    11221 atcgctttag gttgggcaaa tatcggtgcc gctgtagcac cagatgctgc attagcatca
    11281 gtagcatcag caattatttt agttttaggt ggacaaggtg ttaaaggtgt tccttctgcg
    11341 atcgcgattg ccgttccttt ggctgttgca gggttgttct taacaatgat cgtacgtaca
    11401 atcgctgttc caatcgttca tttgatggat gcggctgctg aagaaggaaa catccgtaag
    11461 gttgaaatgt ggcacatcat tgctgtatgt ttacaagggg ttcgtatcgc ggtcccagca
    11521 gcagcgttgc tatttatccc agcacaaact gtgcaatcat tccttgaatc aatgccagca
    11581 tggttaacag atggtatggc tatcggtggg ggaatggtcg tagctgtagg ttacgctttg
    11641 gtaatcaaca tgatggctac aaaagaagta tggccattct tcgttattgg tttcgttgta
    11701 gctgcaattt ctcaattaac attgattgct ctaggtgctt taggtgttgc attagctctt
    11761 atttacttga acctttctaa aatgggtggt tcatcaaata atggaggcgg aagcaactct
    11821 ggtgaccctt taggcgacat tttgaatgac tattaatctt gaaggaggaa aataaaatgg
    11881 cagaagaaaa aatcaaatta tcaaaaaaag atcgtttagc tgttgcgtgg cgctctacct
    11941 tcattcaagg ttcatggaac tacgaacgta tgcaaaacgg tggctgggca ttttctatga
    12001 ttccagcaat caaaaaatta tacaaaacaa aagaagaacg ttctgcagca ttaaaacgtc
    12061 acttggaatt ctttaataca cacccataca ttgcttctcc aattttaggg gttacattgg
    12121 ctctggaaga agaacgtgcg aatggcgcgc ctgttgatga tgtagcgatt caaggggtta
    12181 aagtaggtat gatgggtcct ttagctggtg ttggtgaccc agtgttctgg tttacagtac
    12241 gtccaatgct aggtgcacta ggtgcttcat tagctatggg aggaaatatc cttggaccaa
    12301 tcatcttctt cttaggttgg aacattattc gttgggcatt catgtggtat acacaagaat
    12361 ttggctacaa agctggttct aaaattactg atgacctttc tggcggattg ttacaagacg
    12421 taacaaaagg tgcttcaatt ttagggatgt tcgtattagc tgcccttgta caaagatggg
    12481 tatcaatcaa attcttacca gttgtatcaa ctgtaaaatt agataaaggt gcttacatcg
    12541 aatgggataa attgccttca ggtggtgaag gaatcaagag tgcatttgaa caagttaata
    12601 atggcttagc cctttctcct gaaaaggtaa caacattaca agacaactta gaccaattga
    12661 ttcctggttt agctgcatta ggattaacat tgttatgtat gtggttgctt aagaaaaagg
    12721 tttctccaat cgttatcatc cttggtttat tcgtagtcgg tgttgttgga cacgtcatcg
    12781 gacttttata atccataaaa atatagctcg ggcgttgtcc cgagcttttt ttatatagta
    12841 tactgttcat aaacaaatat ctggagggag aaaatggttc aatcaatcaa tacaaaagta
    12901 gacttggtaa ttgatgctac ttcgtttacg ggtctgacag attacgggca aatcatgata
    12961 ggtgataatg gttttgagtt ttaccatgcg cgagatagac gcaaatatat ccaaattcca
    13021 tgggaagaag tggattatgt actagcatca gtcatgctaa agggaaaatg gattcctcga
    13081 tatgccattc aaacgaaaaa aaatggtaca tacacatttt cttccaaaga acctaaaaaa
    13141 gtgcttcgtg cgatcagaga atatgtagat gaagatagaa tggtacaatc attgagtttc
    13201 tttgatgtag tgaaacgtgg tattcgtagt atgtttaaac gcaagtaaaa aataaagaaa
    13261 acttctaaga ggaggttttc tttatttttt tactttgcag aagaaaatat gaaatagcaa
    13321 aaccaattat ttgtcccctt taaatcccat atgctaaaat tgattagcaa agaaggaggt
    13381 tatattatga gttggttatg gacattgatt gttggagccg tgatcggagc aattgcaggt
    13441 gcgatcacca gtaaaggaaa ttcgatgggc tgtgtaacga atatcattgc tggactagtc
    13501 ggttcaagta ttggacaagc gattttcggc gaatggggac caaaagctgc aggtatggca
    13561 cttattccat ctattttagg cgcagtgatt ttggtagcag ttgtctcatt tttctttgga
    13621 aaacgatcat aagtttttac aaaatagtaa actaaaagga gttgcagcga gactgtgact
    13681 cctttttggc tttatttatt taaaataaaa agaagttttc cggaaatttt tatttaactg
    13741 tcgtgtacga agaaaagttt gctataatgg aaaaaagcgt gcaaagaaag agggagtttc
    13801 attatgatgc tacgtgtaga aaaattgcgc aaaaaaatgc aagaagaaaa tttggattca
    13861 tttttggtta ccagtccgta caatcttcgt tacttaacga actttacagg tacgacagga
    13921 ttagctgtta ttactttgga aaaagcattt tttattactg attttcgtta taccgagcag
    13981 gcggcagcgc aggctcaagg gtttgaaatt attaaaaatg tcggacctat ttttgatgag
    14041 gtagcaaact tagtacgcaa agaagaactg cactcattag cttttgagga aacaacagtc
    14101 tcatttttag aatattcggt tttagaagaa atcatcgatg cggaattagt acctgtttca
    14161 cagatgatcg aagaactcag agaagtgaaa gatgaagaag aaatcgctat tatcgaaaaa
    14221 gcatgtcata ttgcggatat ggcatatgat cacatcctga aaatgatcca accgggcatg
    14281 actgagattg aagtcgcaaa tcaactagac ttttatatgc gttctcttgg cgcttcaggt
    14341 gtttcttttg atacgatcgt tgctagcgga ttgcgttcgg ctatgccgca tggtgtagca
    14401 agcaaaaaaa tcatcgaaca aggtgacttg atcacattgg actttggttg ctattacgaa
    14461 gggtacgttt ccgatatgac acgtacattc gctattggtg atcctgggga aaaattaaaa
    14521 gaaatttatc aaatagtctt agatgctcaa ttagcagtta ttgatgctgc aaaaccagga
    14581 atgactggtg tccaattaga tgcagttgct agagattata tttcaaaaca tggttacggg
    14641 gaagcatttg gacattctac aggacatggg atcggtttag agatccacga aggaccaaac
    14701 gtttcttctc gtgcagaaaa gcaatttgta ccaggaaatg tgatcactga tgaaccaggg
    14761 atctacttac caggaatcgg tggagtacgt attgaggatg acttgttgat cacagaagat
    14821 ggaaatcgtg tgttgactcg ttcaccaaaa gaattgatca tcttatagtt tcatcaatag
    14881 aagaagtaag cgtaaaaatc agtgttcaca gactttgtta tagaaaatca ctcgatttaa
    14941 tgatacacta tagaagaact tttaagctgt aagagataat aaagttgggt gttttctcca
    15001 attcatagca gtttgcagct gatcggcggc agttttctta ccacgtgatc actatgccgc
    15061 atcatagaga attcggatgt atctcgtgct taggcaaagg gaggaataaa taaatggcag
    15121 atgaaaaaaa tttgatttta aacgcaaacc aagatttagg agagatcgtg atcgctcctg
    15181 aagtcatcga agtaattatc gggattgcag cttctaaagt agaaggcgta tacggaatgc
    15241 gcggaacttt tgccagcaat gtcactgaat tattaggacg tgcagctcac ggaaaaggtg
    15301 tttacttagc aaacgaggaa gatggcttga aagtagatct ttactgttat ctagaatatg
    15361 gtgtttcagt tcctaaagta gcaatggaaa tgcaggaacg ggtcagccag caagtccttt
    15421 tcatgacgga tatcgattta tctgaagtca atatccatgt agtagctgtt gttcctgaaa
    15481 aattagaaca accaacaatc gaagaacttt ttgaagacga agaggaagag aatgaataaa
    15541 gaattatcaa gacacgagat tcgggaaatg gcattgcagg ctttatttcc attagacttc
    15601 aatgcagacc taacaaaaga agatgcgatt ttcaacgcaa tcgaattaga ccaccgcgac
    15661 atgatcaacg aagatgaatc agagtttgtt cctgtttatc ttgatacgct agttggcggt
    15721 gtctgtgcaa aaaaagatga attggataaa gtgattgaaa aacatttaaa aaacaattgg
    15781 cacatcaatc ggatctcaaa aatggatttg gtgatcttgc gtatcgcgat ttttgaaatg
    15841 acttatgtga cagatgtacc agcggctgtt gctttaaatg aagcaatcga gttggcaaaa
    15901 acatttagtg atgaccgttc acgtaaattc gtcaacggtg ttttatccaa tgtattgaaa
    15961 gaattagaag ctggggcgta agtcctagct tttttctatg aatcatcata aacctgttat
    16021 aaatcgggaa aattctatgg tagaatgaaa acacaaaaaa tatctgggag tggttagatg
    16081 gcagaattga ttaacggaaa agaattagct gaaaaaatgc aggcagagat tgctgaaaaa
    16141 atccaaaaat tgaaagataa tggtatccat cccggattag tcgttttatt ggtaggggaa
    16201 aatccagcca gccaaatcta tgtaagaaat aaagaacgtg tagcaaaaga aatcggaatc
    16261 cattcattgg tagagcgtta tcctgagacg atttctgaag acgaactact tgcagaaatt
    16321 gaaaaataca atcaagatcc tagttttcat ggtatattgg tccaattacc attgccaaag
    16381 catatagatg aagaaaagat cctgttagct atccgccctg aaaaagacgt agacggtttt
    16441 catccgatga atttaggcag actccttgcg ggtaaaccgg acaagattcc ttgtactcca
    16501 tacggcatca tgaaaatgtt tgaagcttat tctatcgatc cggcgggtaa acgagcagta
    16561 gttatcggac gaagcaatat cgtcggtaaa ccgatggctc agctactctt gatggcagat
    16621 gcaactgtta ctgttgctca ttctaaaacc gaaaatctgg ctgaactggc acaagaagca
    16681 gatattttag tcgtagcaat aggacgtgga cattttgtca caaaagaatt cgtaaaacca
    16741 ggtgctgtag tgatagatgt agggatgaat cgtgatgcta acggtaagct gatcggtgat
    16801 gtgaaatttg atgaagtgga gcctattgca ggctggatca ctcctgtgcc aaagggtgta
    16861 gggccaatga ctatcacgat gctgatgtat caaaccgtaa aatctgccga agcttttgga
    16921 gcaggtgaat agatggcaca agaatattta actgtcacta cattaacgaa gtatttgaaa
    16981 agaaaatttg atgccgatcc ttatttagaa cgcgtatatt taacaggcga aatatcgaat
    17041 ttccgtttac gtgccaatgc ccatcaatat ttcagcttaa aagatgacca tgcaaaaata
    17101 tctgctatta tgttcaaagg agcattccaa aaattacgat tccagccaaa agaaggaatg
    17161 aaagtccttg tcgttgggcg tatttcatta tatgaagcgg gaggttctta tcaaatctat
    17221 gtagagcaca tggagcctga tggaataggt gctttatatc aagaattgga agaacgaaaa
    17281 gaaaagctga tgaaggaagg cctttttcaa gggcctaaaa aaatgctgcc acgtttccca
    17341 aagcgaatcg cggtccttac cagtccaagc ggagcggtta tccgcgatat catcacgacg
    17401 gtgaaaagaa gatatccaat tgtccaattg gttttgttcc caacagttgt acaaggaaac
    17461 caagcagcgg acaatgttgt caggaatatc cagagagtag aagagatggg caatttcgat
    17521 acaatgatca tcggtcgtgg gggtggttcg attgaggatt tatggccgtt taatgaagag
    17581 cgggttgctc gggcgattta tcaagctaat acgccggtga tttcatctgt aggacatgaa
    17641 acagatacca cgatcgctga tttagtagca gatgttcggg ctgccactcc aacagcagct
    17701 gcagaattag ctgttcctgt tttgtcagaa gagttgatgc gcattcaaga acggcaagct
    17761 agattgcagc aggcgtttgt acgccagatc cagcgcaaac aagaacggtt cgagcgtgct
    17821 cgacgttcct atgtatttcg gcagcctgaa agattgtatg aaggtcagac catcaaatta
    17881 gaccagttga aacagcgatt atatcaagct acacagcaaa tttatcatgc gaaagaaaaa
    17941 caaacgatcg cattaagcca ccaattggaa caagtggctc cgctttatcg agttaaagca
    18001 gctcgccaag aaactgctta tctagaaaaa cgcttagaag agaaaatcca acaatatatg
    18061 aaacaacagc agcagcgttt tgctcaagct gttcaatctc ttgatttgtt gagtccattg
    18121 aaaatcatgg gaagaggcta cagctatacg acgttaaatg atcaagtagt aaaaagtgtc
    18181 accgagattc atcaagggga tttgctgacg atccattatc aagatggaat cgttaaagga
    18241 caagtacaag agatagacaa aggagaataa aaatatggaa aatccaactt ttgaagagtc
    18301 actgcaagaa ttagaaaaaa ttgtcatgca gttagaacaa ggagacgttc cattagaatc
    18361 agctctagat tcgtttaaac gaggaatgga attaagcaaa cattgccaag atacattagc
    18421 taaagcagaa gagaccttga cgaaaatgat gacagaatca aatgaagaag ttgattttga
    18481 cggaaacgag gaaagctgag atgagattaa ctgacttttc agctattcat ctacctgctg
    18541 tagaaaaaga aatcttgtct tttttagatg agcatacaac ggatagagga ctctatgatg
    18601 cgatgagtta ttcagtgaaa gcaggcggga aaagaatacg tcccttatta cttttaacgg
    18661 ccgttgcttc ctttgatgag cctattgatg ttcccgtcta tcaagtagca gctgctttag
    18721 aaatggtgca tacgtattcc ttgatccacg atgatttgcc tgcgatggac aatgatgatc
    18781 ttcgtagagg aaaacctacc aatcataaag tattcggcga agcattagct atattggccg
    18841 gagatggttt gcttacagga gcattccagc taatcagtat ggcacactta ggtaattctc
    18901 ctaagcttct gctgcttcag caattagctg tttgtgcggg atcacaaggt atggttgctg
    18961 ggcaagctgc agatatcgag ggcgaatcga aaaagctttc tttagaagaa ttagcattta
    19021 ttcatgaaag aaagacaggg catttgattc gttatgcctt gctggctggt ggcatattag
    19081 cgaagcaacc tgaagaaatc ttattgctac ttcaacgatt agccgaacat ttaggtttag
    19141 cttttcagat aagagatgat ctactcgatg tgattggtac aacgaaaaca ttagggaaaa
    19201 cagctggtaa agatgaacgt atggaaaaaa atacttaccc gcgtttatta ggcctagaaa
    19261 agacacgtga ggcgttggag attgagctgt tatccgccaa caagatcata gacaaattag
    19321 aagaggacgt tttttctttt gatggcgggc tgatgcgcca gatgatcaag caatttgatg
    19381 tggagaaatg agggaaagaa tggaaaaaga acgcgtagat gtattagcgg tcaaacaagg
    19441 attatttgaa acaagagaac aagccaaacg ttcagtgatg gctggtttga tttacaacga
    19501 aaaaaacgag cggtttgata aaccgggaga aaaaattcca gtgagtagtg aattaagagt
    19561 caaaggtaaa aaacttcctt atgtttctcg agggggatta aaattagaaa aagcactcaa
    19621 agcatttgat ctatctgttg aaggaaaaac attgttagat attggtgcat ccactggcgg
    19681 atttactgat gcagctttgc aaaatggcgc aaaaatgagt tatgctttag acgttggcta
    19741 caatcagcta gcttggaaaa taagacaaga tcctagagtc gtcgtaatgg aaagagtgaa
    19801 ttttcgttat gcaaaacccg aagactttac cttaggaatt ccagaagttg ctgttatcga
    19861 tgtttctttt atttcactaa aactgatgct gcctccatta catgctattt taaaagaaga
    19921 gggagaagtg attgctttaa tcaaacccca attcgaagca ggcagagaag ctgtagggaa
    19981 aaacggaatt gttcgtgacc ctcagaccca tcaaaaagtt ttagaagaca ttttgtcatt
    20041 tgcggcacaa ggtggatatg atgtgctgga attaagttat tctccgatca cggggggaga
    20101 aggaaatatc gagttcttgg ctcacttgag gaaagtaccc gaaagcggaa caatcaattc
    20161 agctattaat atggcagaag tggtttcaaa tgcacacgaa cagtttgacc ataaataaat
    20221 tgtaactgtg aaaatcaagt gagaagtatg cggattcttc tttattatac caaggaaata
    20281 agctatcatt gattaagaag aatatgctaa ggagcgaaga cgtaatgaga aaaaaagatc
    20341 ggcatcgttt gattactcga ttgttgagtg agcaagatat ccgaaagcag gaagaatttg
    20401 ttgaaatcct gaaaagcaaa ggaatatctg ttactcaagc tacgatttcc agagatataa
    20461 aggaactgaa actgatcaag gtaccggctt cagatggcgg ctaccgttat agcataccag
    20521 ctgaaacaaa cgaagatgta aatactaaat tggaaaaact attaaaagac gctttcgtgg
    20581 cagttgacca aatggaaaaa tttgttattt tgaaaacatt gccgggaaat gcttcggcag
    20641 cagcaaattt gattgataaa cgttacaaga aagaattatt ttcgattatc aatgatgacg
    20701 ataatgtttt gatgattaca cgaactgaag accaggcagt tttattgaag aaagacttcc
    20761 tgcattacct ttaagttgag gagcgaatgt gatgctacaa gaaatcagta ttactaactt
    20821 tgcgattatt ccggaattgc ggctttcttt tcacgaagga atgaccgcgc tgaccggaga
    20881 gactggtgcg ggtaaatcca ttattatcga tgctttaggt ctgttagcag gaggaagagg
    20941 ttcaagcgat tatatacgtc aaggagcaga aaaatgtgtg cttgaagggt tgtttgaact
    21001 accaaaacaa gaaggattct ctgaactgat ggttgaatta gggatcgaaa cagatgagga
    21061 caatctgatt gttcgacggg atatgtcctt aactggaaaa aatgtttgtc gagtgaatgg
    21121 tcatattatc acattagcta atctgagaag aatcggcagt tatttagtag atatccaagg
    21181 acaaaacgaa catcaggaac tgctccagcc tgaatcacat cttgctttat tggatcgttt
    21241 tggagatgta gctttccaac agaagaaaaa gagttatcag caagaatata tctcttatcg
    21301 tgagctggaa aaaagggtac gaaaagtgca gcaaaatgaa aaatcctatg ttcagagaat
    21361 agatatgctc catttccagc aagaagaaat agctgctgct gatttgcaag tcggagaaga
    21421 agagaaatta aaagaagaaa gagaaaaact tagcaattat caaaaaattg ctgatggatt
    21481 agctgcaggt tacggagcac tgacgaataa tgaacaaaac agtgtagatg gtgttggctt
    21541 ggccgtttca gaactgcaag ggatcgccca tctagatgtg gagtatgaag caatttatga
    21601 aaatatccaa agtgcttact atttgctgca agatgcaatc ggcgatatga gtcgtcagat
    21661 tgatttattg gagttagatg agagtcgttt agaagaagtt acgcaacgtt tagaattaat
    21721 ccgacagttg aaacgtaaat acggcgaatc cattgagtca atattggctt actatgacga
    21781 aatcaccgaa gagctagctt cttctgattt ttcagaaggt caattggaca aaatgaaaga
    21841 ggaactagag caaaaagagc ttctacttca gcaacaagcc gcagatcttc atgaagcgcg
    21901 taaaaaaatc gcaaaagaat tggaaaaatc cattctgcat gaattgaaaa gtctgtatat
    21961 ggaaaacact gagtttgagg tacgtttctt aaaagaagaa aatagacaat tgaatcatga
    22021 tggatttgac caaatcgaat tttacattac gaccaatcca ggagagccac tgaagccttt
    22081 ggtgaaagtc gcttctggtg gcgaactgtc tcggatgttg cttgctttga aaactatttt
    22141 ttcttctgag caaggtgtga caagtattat ttttgatgaa gtggatacag gtgtgagcgg
    22201 aagagttgca caggccatcg cagataaaat ttctcaaata tcgaaatact ctcaagtttt
    22261 gtgcatcact catctgcctc aagttgctgc agtcgccgac tatcaatatt atattgtgaa
    22321 agcagtgatt gatggacgta cgcaaacttc tgtttcagag ttgaaaacaa aagaaagaga
    22381 agaagaaatt gcacgtatgc tggctggaag tgagattaca aaactcacac tcgaacatgc
    22441 aaaagaacta ttgaaactcg caaaaaggac ctgagccacc tcgcagtggt tcaggtcctt
    22501 ttcagcagct gatagctata ttttattttt acatgacact cattacagca gtcaatacaa
    22561 cagatccaat cgttaaaatc agcattgtcc aaatgacaaa ttttgttact ttagcaaaag
    22621 tacttgtttg ttttttttca cgcattgttt tcaacctcgt cattaattag ttgattcaag
    22681 tgtacaatct tttttccatt tccacaagag ggctttttta taaaaacttc ccttttttta
    22741 aataataggt agttacgata caaataaata atgttaatag aactagccat ataaaggcat
    22801 catccctttc agcaataggt aacttaatgt tcattccata gatactgccg acgattgtcg
    22861 gtatagttaa aataatcgtt aaagaagtta aaattttcat aatattattc agattattcg
    22921 atacgattgc tgaaaaagtc tgattcattt gttctactag ttttaattga atgcgagaag
    22981 tagtcattgc ctgctctgtt tccaccaata catcacgtaa atgatttttc aaagcatgat
    23041 tttcttggaa aagtttattt tgcgctagtt ctttcaatgc atctaaatta gcagaagtcg
    23101 cttctctgaa ataaacgagg cttttttgga tatccatgat ttgataaagt tgtttgtttt
    23161 cagtggatac ttgaagtttg gcttccaaag tatcgcattg agattgaagc gtagctaaat
    23221 aactgttgta agagagtgtg acctgccaaa tgaattgaaa gaagatattg agattaggcg
    23281 aaatatcact ttttggaaag gtctggctaa agactttctt taaaaacagt ggttcatgat
    23341 tcgtaattgt gataagcttc tttttgggcg tcaaaataat agagagcggg tatgtatcca
    23401 cttgaaaata accgctagga cttgttttag caaaaggata ttgtaacaat aataacgctg
    23461 gctttgtcaa ctttgattga ttgaattctt ctgtacggga attttctgca tcgtccaata
    23521 tggaagtgat gtaatctgac ggaatttcaa attgatgtgt cagctgatga atctcttctt
    23581 gattaggacg ttctacacaa taccagatcg tttggtcagt ttcctttccg gtattacgca
    23641 gtttctcatt atctaatgta aaatatttga tcatgatttt cctcctgttg cctgtttctt
    23701 ttattataac ggatagggaa ttggaataca tggaatgtgt ttgtaagata tagaatataa
    23761 ctgcataaat ttaaataaaa tgaaacagtt gtgtaaagta tatacagtat acttgaagca
    23821 acgataaaaa aggagtttac gttcatgggc acattcacac cacttatctt gttttggtat
    23881 atttacccgg taatcgtttt gtttggttgc caatttcttg taaaattatt ttcgttaaat
    23941 cgtcgtttta aaataaaagc ccctgatttg gcgattcctt ttttgtgggg cggtatgcat
    24001 gcattgtcta gaaatacagg gacaatttct atcttaccgt ttttctttat ttctgttttg
    24061 ctaatgggaa tttgtattgc tgttttccaa gcatattatt atgaagaaat tatttatccg
    24121 cgttatttca agatgacttg gcgtttggtt tttctgttga caatcgtctt gtacgctgtc
    24181 ttgatcattg tgaacatact ttcttaccta tgaaaaaaat agaaaagctg taaaaagtct
    24241 tttaaaaggc tttttgcagc ttgattttta aaaaaatgtt tatgaataaa aaaagttgtt
    24301 cccggatttc ccagaaaagg tggtagaaag tgggggattg tggtagacta attttagtta
    24361 gtggaggaat ggggggcttt caatgttgat gggtgaattc caacataata ttgatgcaaa
    24421 aggacgttta atcgtgccct caaaacttcg tgaagaactt ggcgaaaagt ttgttctgac
    24481 acgcggattg gatggctgtc ttttcggcta tccgatgagc gaatgggaaa atctggaagc
    24541 taaactgaac gaaatgccgt tggctaaaaa agacgcacgt acttttgtgc gattcttcta
    24601 ttcggctgcc actgaatgcg aacttgataa acaaggacga atcaatatac ccagcacgtt
    24661 aagaaattat gcagctttga caaaaggttg cgtagtcatc ggtgtatcta accgaattga
    24721 aatttgggat gagacacgat ggcaagattt ttctgcagca gcagaagaga actttgacga
    24781 aattgctgaa agtatgattg atttcggact ataagaatag gaagaggctg actaatgact
    24841 gaaacatttc aacactatac agtcatgttg aaagaaacgg tagatggatt gaacatcaaa
    24901 ccggatggcg tttatgtaga ctgtacactc ggcggtgccg gacatagtga atatttatta
    24961 agccaactaa gttctaaagg gcatctgtat gcgtttgacc aagatcaaaa agcaatcgat
    25021 cacgccaagc tgcgtttagc ttcttatgtc gaacaaggta tggtcacatt tatcaaagcg
    25081 aacttcagag aattagaaga acgcttgagt gagcatgtag ataaggtaga cggcattttg
    25141 tatgatctag gggtttcctc tcctcagcta gatgaagcag aacgtggatt tagttatcat
    25201 caagatgcac cgttggatat gcgcatggat cagtcagctc ctttatccgc ttatcacgta
    25261 attaatgaat attcctacca tgaattagta aagattttct tccgctatgg cgaggagaaa
    25321 ttttccaaac aaattgctcg tgaaatcgaa cgagtacgaa aaacaaaacc aatccaaaca
    25381 actggtgagc ttgtcgaaat cattaaacaa gtcatcccag ctcccgcaag aagaaaaggc
    25441 gggcatcctg caaaaagaat ttttcaagct gtgcggattg cagtaaatga cgaactcggt
    25501 gccgaagagg cctctttaga acaggcaatc cggttattga aagtcaatgg aagaatcagc
    25561 gtaatcacat tccattcatt ggaagacaga attgtcaaaa gtatgtttaa agaatatagt
    25621 acggtacaag atctaccacc gggacttcct gtcatacctg acgaattcca accagaactg
    25681 aaagtcatta ctcgtaaacc aatccttcct tcagaggaag agctaacaga aaacaatcga
    25741 tcacgcagtg caaagttacg tattgcagaa aaaataagaa tgaaagagga gtagaatgat
    25801 ggcagaatta aagaaaatgc aagattacga atatgattta cctgaattgg tggatcagcc
    25861 ggaacaacaa atgcctgatt cttcttcgaa tcaagaaatc attcttccac aatcaccggc
    25921 aaaacgatta aagcagattt ctgctttgga aaaaattgct gtggcaagcg tggcgattgc
    25981 tattgttgct ttatgtgttt taacagttat gctgcgcaca aatatcagcg gagctgaaaa
    26041 agaaatcacg tcaatacaaa cagaaatcaa tgataaaaag caagaaaaaa cgagtttaga
    26101 acaagaaaaa aacgaacttt ctcgtactga acggattaaa caaatcgcag aagaaaaagg
    26161 attgtctatt aatgacgaca atttaaggaa agtgaagtaa atgagtctta aaaataaaat
    26221 tcggcggttt atggaaaaga aaaatctaaa tccgatgaac aatcgcaaaa aagtaggtat
    26281 cattttattt gctacgagta ttggattgtt ctttttattt gccgtccgtt tctcgtatat
    26341 cgttattgga ggtcatgttg ctggtacctc attagctgaa aaaacaaaac agttgtacca
    26401 aggaagtgaa gtagtaaaag caaaaagagg aacgatttat gatcgtaacg gtgtggcgct
    26461 cgcagaagat gcctcctctt attcaattaa agcgatactc tcaaaaacat atacctctgg
    26521 ggataaaaaa ctgtatgttg aagaaaagaa ttttgataaa atagcagaaa tcctgcataa
    26581 gaatctttct atagacaaaa aagatgcact gaatatttta gaggacggcg caaaaaaaga
    26641 gctgtatcaa gttgaatttg gtagctatgg gaaaaatatc tcccaagaaa ccaagcaaaa
    26701 catcgaagcg gacatgaaaa aagaaggtgt cgctggtctt tattttgtcg accatcaggc
    26761 tcggatgtat ccaaatggcg tcttttcttc tcattttatt ggatacgcag ttccagacaa
    26821 agatgagaat ggcttagttg gtaaactagg tttggagtct gcttacaatg atatcttgag
    26881 cggtaaagat ggtaagatta tttatcaaaa agataatttt caaaatcctc tgccaggtac
    26941 agtggcagaa gaagaaaaag ctgtcgacgg acaagatatc tacacgactt tagacagcag
    27001 actacaaagt tatttagaaa cactgatgga tcaagtaaat gaagaatatc agccagaaga
    27061 attgacagca gtcctgatga aagcaaaaac cggagaaatc ttggcaatgg gacaacgacc
    27121 tactttcaat cctgaaacaa tggaaggatt gactggaaaa gatgctatct ggcgtaattt
    27181 cttggtacaa gatagttatg aaccaggatc aaccatgaaa gttttcacta ctgcagctgc
    27241 tatcgaagaa ggagaattca acgagaatga aaccttccaa tctggaaaaa tccaagtaga
    27301 agatgctacg atcaatgacc atgactttgg tgaaaaaggt gtgctgacca tgcgtcaagc
    27361 tctttcatgg tcaagtaacg tcgggatggt catactggaa cagcgattag gcggacgatg
    27421 gtataactat ttacaaaaac tgggatttgg acaaagtact cattctggat tagatgatga
    27481 agtaaacggt gctttaccta cattaaatat tgtcgaccga gcaatgagtg cttatggaca
    27541 agcggtaggt gtgacgaatt tccaaatgat gaaagctttc acttctattg cgaataacgg
    27601 tacaatgatt caacctcgat atatcagcaa agtggtggat ccccaaactg gagaagagcg
    27661 aacaactcaa acagaagttc tagggcaacc tttttcaaaa gaaacaacag aaaaagtccg
    27721 tgaatatatg agagatgttg tcgaaagcga aaactacggt agtgcttatg gtgtatatag
    27781 tgtacctgga tacaatgtat cggcaaaaaa cggaacagcc caaatcgctt ctgatacagg
    27841 gggatatcaa acaggagata cagcctacct gtattcgatt gtggagatgg ttccttctga
    27901 agatccagac tatgtcttgt atctaacaat gaaacaccct aagacatatg atcgaatggc
    27961 attggctaaa atcgcaaatc cattgatgaa acgggcaatg gattttaaag aaactgaaga
    28021 agattcagat acagaaacaa aaacagaaaa agtatccgta gccgattatc gtaatcttga
    28081 agcggacgtt gcagcagctg atgctcaaaa aagtggactg caacctgtag tgatcggtaa
    28141 tggtaaaaaa gtacaaaaac aatctactgc caacggtgat cagttgatct ctggagaaaa
    28201 actgatccta tatactggtg gtgataagct gatgcctgac gtaacaggat ggtcaaaagc
    28261 agatatcatg aagctgggga aaatcctcgg tattgaagtt agttttgatg gagatggtta
    28321 ttgtgtcaaa caagaacttg ctccatatga aaaaatcact gaagacaaac ttagttttac
    28381 tttagaagaa taagaagaga aataggagag aaaagagcat ggaatggaca caagcattga
    28441 ttcccattgt cagcagttgt gcaatgacaa ttgccgcaat gccgctattt attggttatt
    28501 ttcaaatgaa aaagcaaggt caggcgattc gtgaggaggg accaaagtgg cacaatagca
    28561 aagccggaac tcctacaatg ggcggcttag tgtttctgat cggctctatt ttgacaggaa
    28621 tttgggttgg agcttggcaa aaacagctaa ctcctactct tttcatcttg ctttttgtat
    28681 tagcgttata cggagtaatc ggctttcttg atgattttat aaaaatattc aagaaaagaa
    28741 acatgggact gaactcgaag cagaaattga ttggacagat tctaggggga atcatctttt
    28801 atcttgttta ccgttctgaa ggttatccag gtgtattgaa tttcttcgga ctagatctac
    28861 ctttaggaat catttatggt attttcgctc tcttctggct tgttggattt tcaaatgcag
    28921 taaatctgac agatggcatc gatggattag ttgctggctt aggaagtatc tcttttgcag
    28981 cttacggtct aattgcttgg catcagcatc agtatgatgt attaatcatt tgcttaagtg
    29041 ttttaggagg tttactgggt ttcttcgtct acaacagaaa acctgccaag atttttatgg
    29101 gagatgtcgg ttcattagcg ttgggcggac ttttagcggc aatttctata atgctaaacc
    29161 aagaatggac attgcttttg attggtttga tctatgttat ggaaacagca agtgtgatgc
    29221 ttcaagttac ttcctttaag cttacaggaa aacgaatttt taaaatgtct ccaattcatc
    29281 atcactttga aatgtgcgga tggtcggagt ggaagattga tacagttttt tggttgatca
    29341 gcattgtgac ttcgttgatc acattatgga tcgtttggta ggagatgacg ggaaatgaaa
    29401 aaaatatcaa catatgaaaa taagaaagtg cttgtcttag gactcgcaaa aagcggagta
    29461 agtgcggcca aattattaca tgaattgggc gcacttgtca ccgttaatga tggaaaacct
    29521 tttgacgaaa atccggaagc acaagagctg ctttctttag ggataaaagt aataacaggt
    29581 agtcatccaa tcgaattgtt ggatgaagaa ttttcattga tggtcaaaaa tccagggatt
    29641 ccctacagtc atcctttagt agcaaaagcc caagaaatgg gtattccggt aattacggaa
    29701 gttgagctag cttacgaagt agcggaatgc ccaattattg ggattacagg aacgaacgga
    29761 aaaacaacga caacaacgat gacaggacta ctactgaatg caggagcaga tcaaggaatt
    29821 gcacgtttag cgggtaatat tgggtatcca gcaagtggtg tagcgcaaga agcaaaatca
    29881 gaagataaaa ttgtgatgga attgtctagc ttccaactca tgggaatcac agatttccgc
    29941 cctcatatag cggtgattac caatatctat gaagcacata ttgattatca tggtacaaga
    30001 aaagaatatg tcaaagctaa atggaacctt caaaaaaaca tgacagaaaa agattatctg
    30061 atccttaact ggaatcagtc agaactacaa gaattagcgc aaagaacaaa agcacgcgta
    30121 ctgcctttct cgacaaaaga agtgttggaa gacggtgtgt atgctgacga ttactcaata
    30181 tactataaaa aagaaaaaat aatggaaata tctgaacttg gcgtaccagg taagcataat
    30241 gtagaaaatg cactagctgc tatttctgta gcaaaattgt atggtatatc aaatgaagct
    30301 atacgagaaa cgttgcattt tttccatggc gtaccacatc gtacgcaata tgtaggagaa
    30361 atccaaggca gaaaatttta taatgattca aaagcaacca atattttagc gactaaaatg
    30421 gctctaagtg gatttgaaac gtctaaggtc gtgttattgg ctggcggatt agacagagga
    30481 aatacatttg atgaattaat tccttcatta aaaggaatca aagcaatggt cgtatttggc
    30541 caaacaaaag aaaagttgat ggatgctgga aaaaaagcag gcatcgagac aatagtaaca
    30601 gccgattctg tagaacaagc agttccttta gcattagaaa acagtacaga tggtgatgta
    30661 gttttattat caccagcgaa tgccagctgg gatcaatacc caaattttga aactagagga
    30721 aacagattca tggaagctgt gaaccgatta aaatagaaaa agtagaagcg agcgataaaa
    30781 aatgaaaatt ttggttacag gcggaggaac agggggacat atttatccag ctcttgcctt
    30841 tgtcaattat gtaaagactc aagaaccgaa tgctgaattc atgtatgtgg gagcaaaacg
    30901 aggtctagaa aacaaaatcg tccctgatac aggaatgcct ttccatacct tggagattca
    30961 aggatttaaa cgaaaaattt ccatgcataa catcaagacg gtccgattgt ttcttaagag
    31021 tatccgtcaa gcaaaaaaaa tcctcagtga ttttcaacca gatatcgtta tcggtactgg
    31081 aggatatgtt tccggagcgg tagtgtacgc tgcagccaaa atgggtattc caacagttat
    31141 ccatgaacaa aacagtgtac caggtgttac caataaattt ttaagccgat atgtggatcg
    31201 gatcgctctt tcatttaaag atgcggcttc cttttttcct gaaaacaaag cagttcttgt
    31261 aggtaatcct cgagcacaag aagtagcaga tactaaaaaa tcagatattt tgaaaacatt
    31321 tgatttggat ccagaaaaga aaacagtctt gatttttggc ggtagtcaag gagcacttaa
    31381 aatcaatcaa gcagtatcag tttttttaag tgaatatatt ccttcttctt accaagtttt
    31441 gtatgcttca ggagatagat attatgaaga gatcctaaat aaaataaatc ctgaaataca
    31501 aaatattagt gtccagcctt atatcaaaaa tatggcagag gtcatggctt ccagtgatct
    31561 gctggtgggg cgtgctggtg caacttcgat cgcagaattc acagctctgg ggttaccggc
    31621 agtgttggtt cccagcccat atgttacgaa tgatcatcag actaaaaatg caatgagtct
    31681 tgttcacgca ggagcagcaa aaatgattgc agataatgaa ctaacaggtg aatcactaag
    31741 tcagacagtc aacgaaatca tgggtgatga agaattgcaa aagcaaatgt gccgagcttc
    31801 taaagaacaa ggaatccctg atgcttcaaa acgtctttat gacttagtaa aacaaataat
    31861 caaaaaataa aggcggtggt cttagtgagt aagaaaaaag aaccaaaaaa attgtctcat
    31921 ccgtcttctg atgaaaacaa tttgactcct tggcaaaagg ctaaccgaaa atatctggca
    31981 gaacaagaga tgaaaaacca agagccaaaa aaagaagaca taacattaga tacacccctt
    32041 tcagattctg aagaagaaaa aacggttcaa gaggaacagc aagaagaaag ccagtccgag
    32101 aaaaaaatcg aattttttga agagatcaag caaaagaaaa acggtggacc atataacggt
    32161 tcttttttga accggctgcc caatttaaaa agtcaacggc acaaagtact atttcgtcgg
    32221 ttagctttga tcatcactgt attgggtata ccgctgattt ttttgatcta ttatgtttct
    32281 ccttatagca aattacaagc agttgcagta tcaggcaata agacagtcaa cagccaagaa
    32341 atcatctctg atacaaaatt gtcattagga gaaaatgttt ggggacagta ttttcatcga
    32401 tctacttata tcgatcgcct taaaaaagca cagccaagaa tcgaaacagc aaatatacat
    32461 ttcaaaggga tgaatgaatt cgatttggat gtaacagaat ataaagagat tgctttgatc
    32521 gcaaaaaaca atcaatacta cccagtgatt gaaaatggaa cagtattaga tgaaaaagta
    32581 gcaaatccta caaaaaatct ccctatcttg gaagagttca aagactctgc aaaaatcaaa
    32641 gaattaacaa agcaatacaa tcagttatca tcagaattac aaaaagcaat ttctgaaatc
    32701 aagtacacgc caagagcaag caataaaaat ctgatccaat tgaatatgaa tgacggcaat
    32761 caagttattg taaatatcaa taatcttgcg aaccaaatga aatattattc gcaagtagcc
    32821 aaagatatgg atgaaaaagg tgtgatcgac atggaagttg gtatcttctc gcatccttac
    32881 ggtagcactc aagaaacgga agaatcgggc caatcggaag aaacaactga aagtgaagaa
    32941 aatgcggatc aaacaaacga atcaagtgaa gaggcagaaa cgcaaaaagc acaaacacct
    33001 ggatcgtcta gcacaaacgg atcatctgat tcaaatgatt caagtgaaac aagtcaaata
    33061 gaagataatc caagtacaac tccgtcaagt ttaaatgaaa attgataaaa caactttaaa
    33121 aagtaagaat gtactttcta aaaaccagta atttatggta gaattggaag cagtgaatat
    33181 atctattaat aagtatattt taaaacggac gctagttgtt cgcttgtata tggaatagta
    33241 agtaggaggg aatcccattc atggcaaaaa caggaatgta tgtaggcctt gatattggaa
    33301 cgacatctgt taaagttgtc gtggctgaat atatcgacag ccaaatgaat attattggag
    33361 taggaaacgc aaaatcagaa gggattaacc gaggcattat cgttgatatc gataaaacgg
    33421 tccaagcgat acaacgagca gtacgacaag cagaagaaaa agcaggtatc cagatcaaag
    33481 gcgtaagtgt cggtttgcca gcaaacatgc ttgaagtaga aaattgccag ggaatgattg
    33541 cagttaacgg agattcaaag gaaatcaccg atgaagatgt cagaaatgtg gcttcagctg
    33601 cccttgttcg ttcaatacct cctgaacgtc aaatcgtgtc aatattgcca caagatttta
    33661 ctgtcgatgg gttcgaggga atcaaagatc ctcgtggaat gatcggcgta agattagaaa
    33721 tgtacggtct gttgtttaca ggacctaaaa cgatcatcca taacatacgt aaatgcgtgg
    33781 aaaatgccgg attaatcgtc aacgaaatgg tgattactcc tttagcgctg actgaatcaa
    33841 ttctttctga cggagaaaaa gattttggta cgatcgtcat tgatatgggt ggcggccaaa
    33901 caacaacggc tgttatgcat gataagcaat tgaagtttac caatcttgac caagaaggtg
    33961 gcgaatttgt cactaaagat atctctattg tattaaatac gtcatttaac aatgcagaag
    34021 cgttgaaaat aaactacggg gatgcatacc cagaacggac atcaccagat gaagaatttc
    34081 cagtagatgt gattggtcag tcagaaccag tgaaagtcga tgaacgctac ttgtcagaaa
    34141 ttatttcagc tcgaatggaa cagattttca acaaagcaaa agatgcattg gaccaaatcg
    34201 aagcattaga gttgccaggt ggcgtcgtat tgacaggcgg agctgctagt cttcctggtg
    34261 ttgtggactt ggcacaagaa atcttcggcg taaatgtaaa attgtatgtt ccaaatcaca
    34321 tggggctgag aaacccggta tttacaaatg taataagtat cgtggattat tcagcaaact
    34381 tgagtgaagt gtatcaattg gcaaaaattg ctgttacggg tgaaacctca gcagctcgtc
    34441 aaatggtagt tgaacaagaa acaacaaaca catatgagag ctatgaagca cctgaagaaa
    34501 caatctacga tgagccggaa ccaaaagagt ccggagaaaa tgtaaaaaat aaaatcaagg
    34561 gtttctttac aaatattttt gattaattca tcctgggagg aataagatat ggaattctca
    34621 attgataata atatcaatga cggcgcagta atcaaagtca tcggagtcgg tggtggcggt
    34681 ggaaatgctg taaaccgaat gattgaagaa aacgttaaag gtgttgaatt cattacagcc
    34741 aacacagacg tgcaagcatt aaaaaattca aaagctgaaa cagttatcca attaggcccc
    34801 aaatatactc gtggtttagg tgctggttct cagccagaag ttggacaaaa agcggcagaa
    34861 gaaagtgaac aatccttacg cgaagcttta gacggtgcag atatgatttt catcactgca
    34921 ggaatgggtg gaggaaccgg tacaggtgct gcaccaatcg ttgcaggtat cgcgaaagaa
    34981 ttgggcgcat tgactgttgg tgtcgtgaca cgtccattca cttttgaagg accgaaacgt
    35041 ggccgttttg ctgcagaagg tatcgctcgt ttgaaagaaa atgtggatac attattaatt
    35101 atctcaaata accgtttatt agaagttgta gataaaaaga caccgatgct tgaagctttc
    35161 cgtgaagcag ataatgtttt acgacaaggt gtacaaggta tctctgattt gatcacagcg
    35221 ccaggttacg ttaaccttga ctttgctgac gtgaaaacag tgatggaaaa ccaaggtaca
    35281 gcattgatgg ggatcggtgt ggctagtgga gaagatcgcg tagtagaagc aacgaaaaaa
    35341 gcaatctcct ctccattgct tgaaacatct attgatggag ctgaacaagt acttcttaac
    35401 atcacaggcg gtttggatat gacattgttc gaagcacaag atgcttcaga tatcgtagca
    35461 aatgcagcaa ctggcgatgt aaatatcatt ctaggtacat ctatcaatga agaaatgggc
    35521 gatgaaatcc gtgtgacggt catcgcaaca ggtatcgatg aatcaaaaaa ggaacgcaag
    35581 tctagccgac cagctagaca agcacaaatg caatcacctg ctcaaaagac tgtattagat
    35641 atggatcaag ctaaaccaac ttcttcagaa gaagaaaaca gttttggcga ttgggatatc
    35701 agacgtgaac aaaatgttcg tcctagagtt gatgattcca attttgacaa tatcgaaaaa
    35761 aaagaatttg atacattcaa ccgcgaagaa acaaaatctc atggcgatga tgaattaaat
    35821 acgccaccgt ttttccgtcg taaaaaataa aggagaggaa gagcacatga ttgctgacaa
    35881 cttgcagaaa atcaagcaag aaattcagga ttcgtgtgct cttgttcatc gtgatccgaa
    35941 agaagttaca ttagtagctg taacaaaatc tgttgaatcc gctcaagctg aagaattggt
    36001 tagagctggc gttatgaatt gtgcagaaaa ccgagtagat aaattattag aaaagaaaca
    36061 agatttattt gattttcctg aaataaagtg gcatttaatt ggtaatttac agcgcagaaa
    36121 ggtaaaattg attgtaaatg aaattgatta ctttcatgcg ttggacagtt taagattagc
    36181 agaagaaatc cagaagcggt tagagaaaga attatcctgt tttattgaag taaatgtttc
    36241 tggtgaggaa tcaaaacatg gaatttcacc agatgagctt ttaccgtttg tggaatcttt
    36301 agctgcctgc acaaaaatca aggttgttgg gttgatgact atggcgccta aagaagcttc
    36361 tgatgagcaa atccataaag tgtttggtac gctgaaagaa ttgcgtgatc ttgttcaagc
    36421 aaaaggttat gcccatgcac catgtagtga attaagtatg gggatgagtc aagactttca
    36481 aattgcgatt gaagaaggtg caacatttat ccgtgtagga acagcgctat tcaaagacga
    36541 ataaaggagg aacaaaaatg ccgcttttaa acagaggagc aattgctaat tttttcggat
    36601 tagctgatga ggaagagtac gaataccaag attatcctga aacaacaaaa aaggctgtac
    36661 agccaactaa aaaaaataca acacagaatc aatcaactca ttctgtatct gctgcgaata
    36721 ctcatgaaaa acaaaaaacg gcgacttcac gtcctgtaac gcatgaaagt attcagccgg
    36781 ctgaaaagaa aaaagtaatt gaactacatc aatcacctac aaaaactgta gcgaaagaaa
    36841 gaacagcttc aagaacctct acacaaccta aagcaaatct tgctggaaaa atcactgtaa
    36901 tggaaccaag agcttattct gaagctatgg cgattgctaa acgaatcatt gctggagaag
    36961 caaccttagt gaattttcat ttagtagaag aaaaacaagc gagaagaatc gttgattttc
    37021 taacaggaac agtttatgca ctagatggag atatcaaacg tgttggagat gagatttttc
    37081 tttgtacacc gactgggatg gagattgaca gttcaaccgc tcaatctttt gcagatgcga
    37141 atttgtttga tctgtaagag gaggaactac gatttatact attgcactat tacttcattt
    37201 acttcaacgg gcagcctatt tctatagcat tatcttgatg gtatatgcat tgctctcttg
    37261 gtttccaggc gggtatcaat cagggctagg acgattatta gctaagatct gcgaaccgta
    37321 tatcagtttg ttcgatcgtc tgcctttgag gattggaccc ttggatttca caattttagg
    37381 ggcaatcctg atcttgaact tagccgtaca aggtttagca cagatcgtta tatggataac
    37441 tgtccattta gtttattgat tgaagcaaca aaatctttat tctcagaata gataggaggg
    37501 gaaaattttg gatgcaaatg tataccagca ctttcgggca gatgaacgta catttatcga
    37561 ttcggtaggc gattggattg aacaggttca aggacaatat gcaccctatc tgaccgaatt
    37621 tcttgaccca agacaatcct atattttaga aacactgatt cgacaaagca gtgatttgcg
    37681 tttcatgttt tatggcggat atgaacaggc agaaagaaaa agatgtttga ttttccccga
    37741 ttattacgaa cctgtagagg aagattttga aacagcattg tatgaaatcc attatcctag
    37801 caaatttgcc agcctaagtc atgggaaaat ccttggaact ttagtgggaa cggggatcaa
    37861 acgctcttac tttggcgata tcatctcgga cggtgatcgc tggcaagtat ttattgcaaa
    37921 tgaggtggat cattttgttg ctgcacaagt aacaaagatt ggaaaggttg ctgtacgctt
    37981 ggaaccaatc aaatacacag aaatgattat gccgaaagat agctggacac aagaaagagg
    38041 aacagttagt tccatgcgac tagacagtgt gatctctgag atttataata tttccagaca
    38101 gcggtccaag cagctgatcg aagctggtaa agtaaaagtg aactggacag aaaatacaag
    38161 acctgatttt gtacttgaac tattagatat tatttcagtc agaggttatg gcagagtcca
    38221 gatccaagaa cttgagggga agacgaaaaa agaaaagtac agggtactgt tcggtgtatt
    38281 acgtaaataa aataaaaagg tggtttactc atggctttaa ctccattaga tatccaaaat
    38341 aagacattcc cgacaaaaat gcggggatat aatcaagacg aagtagatga tttcttagat
    38401 ttagttgttc gtgactatga ggaattgact caaagaaatc gagaattaga aaaagcagtc
    38461 aaacattctg aagaaaaact tgagtacttc aatgaattaa aagatgcttt gaaccaatca
    38521 atcatcgtag ctcaagatac ggctgataaa gtaaaaacaa gtgcaagcaa ggaatccgaa
    38581 gtgatcgtta cttctgcaca aaacaaagca gatgagttag ttgcgaacgc tgaaaaacgt
    38641 gcacatcaat taacaactga tgcagaagaa aaagcaagaa aaatcttgac agatgcaaca
    38701 gaaaaagcaa gacagcttgc gacagaaact gaagatctta agaaaaaaac acgagtattc
    38761 catcaacgta tcagcttgat gcttgagtct caattagaac aagtgaaaag tccggaatgg
    38821 gatgaaattt tacaaccatt ctccagctac gtgactgaca gccatgaagt gatcaaagaa
    38881 gttttagcaa aacagcttga caatgaaaat gatactgatg taaactcaga cacaggagtc
    38941 atagaagcac ctatgacggc atttgataca caggctattg atatctcgat cgtgcctggt
    39001 gaaaatgaaa acgagtagaa cagaaaagca ctttgttatt cttaaagcga gccgatgaga
    39061 gtggaagttc ggtaagacac tgcatggtga aagatcctct acttgagacc tgcttttccg
    39121 aaattagagt aagaagcagc ggctgacctc gttattggtc acagagagtt tgcactagat
    39181 agatgcaact aaatttgggt ggtaccacgg catgttcgtc ccttgcggct gaacatgctt
    39241 ttttgtgtcc ggaaaacaaa taaaggagtg tatggttgaa tgaaaatgaa agaaaccttg
    39301 caattaggaa aaacaaaatt ccctatgcgt ggtaatttgc caaaccgaga aggcgagtgg
    39361 caaaaagaat gggaagaaaa tcgaatctac caaaaaagac aagagttgaa cgaaggaaaa
    39421 cctagctttg ttcttcatga tggacctcca tatgccaatg gtaatatcca tttaggacat
    39481 tcattgaata aaatcagtaa agacattatc attcgttcaa aatcaatgtc tggctatcgt
    39541 gcaccatatg ttccaggatg ggatacacat ggattgccga ttgaacaagt attggctaat
    39601 aaaggcgtga aacgtaaaga aatgtccatg gcagaatact tggaaaaatg tcgtgaatat
    39661 gcactttccc aagtagataa gcaacgagca gatttcaaac gcctaggagt tgcaggagat
    39721 tgggaacatc cttatgttac attagatcct tcttatgaag ctgcacaagt acgcgtattt
    39781 ggtaaaatgg ctgaaaaagg ctatatttac aaaggattga aaccaattta ctggtctccg
    39841 tcaagtgagt cttctttagc ggaagctgaa attgaatata aagatgtaaa atctccatct
    39901 atttttgtag ctttcaatgt caaagacggc aaagatattc ttgatgaaga tacagctttt
    39961 gtcatttgga cgacaacacc atggacattg ccagcaaacc aaggtattgc tgtaaatcca
    40021 aaatttacgt atgtattggt ggaagccgat ggccgtaagt ttgtcgtagc gaaagatttg
    40081 ctagaaacag tccaatcaga aatcggttgg gaaaatgtaa cagttctaaa agaatttgct
    40141 ggacaagaaa tggaatatat gactgcaagt catccattct atgaacgtga atcacttgtg
    40201 attttaggcg atcatgttac tttagacgct ggtactggat tagtccatac tgctccagga
    40261 catggggaag atgactatat cgctggtagc aaatataaac tatctgtagt gtcacctgta
    40321 gactcaaaag gattgtttac agaagaagca cctggatttg aaggtatctt ttatgacaaa
    40381 gcaaatccta tgatcactga tctattaaaa gaaaaaggag ctttgctgaa gctagatttc
    40441 tttactcata gttatcctca cgattggcgg acgaaaaagc ctgtgatcta tcgggcaact
    40501 ccacaatggt ttgcatctat cgataaattc cgtcagaata ttttggatga agtagaaaaa
    40561 gtagagtggg ttatcccatg gggtaaaaca cgtttgtata atatgatccg tgaccgcggc
    40621 gattgggtaa tttcccgtca gcgtgcatgg ggagtaccac ttccgatttt ctatgctgaa
    40681 aatggagaag caatcatcac accagaaaca atcgaacatg tggcaaaatt atttgctgaa
    40741 catggatcaa ttatctggtt tgaaaaagaa gcgaaagaac ttcttcctga aggatttacc
    40801 cacccaggtt ctcctaatgg cgaatttaca aaagaaaaag atatcatgga tgtctggttt
    40861 gattctggtt cttctcatga agctgtttta cgtcagcgac cagaattatc attcccagca
    40921 gatatgtatt tagaaggatc agaccaatat cgtggctggt tcaactcaag tatcacgact
    40981 agtgtggcta tcaatggtgt agcaccatac aaatcagtta tttctcaagg atttgcttta
    41041 gatggtgaag gccgtaagat gagtaaatct ttaggaaaca tcattgcacc agaaaaagtg
    41101 atcaaacaat ttggtgcaga tatccttcgc ttatgggtat ctagtgtaga ttatgaagca
    41161 gatgttcgtg tttctatgga tatcttaagt caagtggcag aagtatatcg taaaatcaga
    41221 aatacgatgc gtttcttatt agcgaataca gaagatttcg atcctaaaaa agatactgtt
    41281 tcgtacaatg atttacgttc tgtagacaaa tatatgaccg ttcgattgaa ccaagtaatc
    41341 aaagaaatcc gagaagaagg gtacgacaaa tataacttca tgcatattta ccgtacagtt
    41401 atgaacttct tgacggttga tctatcgtca ttctacctgg attttgctaa agatgtagtt
    41461 tatattgaag cagaagatga ttatcaacgt cgttgcatgc aaactgtttt ctatcaaaca
    41521 gctgtagctt tgacaaaatt attgactcct atcattccgc atacagcaga agaaatctgg
    41581 tcattcctga aagaagaaga ggagtacgtt cagttaagcg agtttcctgg ttatgaagag
    41641 tttgcaaacc aagaagaatt gatggatacc tggactgctt tcatggactt ccgtgataat
    41701 gtcttaaaag cattggaaga agcaagaaac agcaaattga ttggtaaatc tttggaagca
    41761 aaactaactg tttatccaaa acaacaagtt cgtgaaatgt taaaagcttt ggatgcagat
    41821 attgcacaat tattgatcgt ttcaccagac tactttgaag ttatggcagc agatgaacaa
    41881 gtgccagata acgctatggt atttgatgat gttgctatta cagtggaaaa agcagacggg
    41941 gaaacttgcg atcgctgtcg ccaagttcgt aaagatgtag gagtagatga aaaacttcct
    42001 catctatgcg gtcgttgtgc aaaaatcgtt gaagacttct atcctgaagc tgtagctgaa
    42061 ggattcgaag aaaagtaaaa gggaaaaggg ggtgtgacat gttctttgtc acaccccctt
    42121 ttgttatcaa tcgtttaatt ttccacgttc acgataccag ttatctggtt gccagatcca
    42181 ttcgaatccg tctttttcaa gtagttcgaa agctgcttta ggtcccattg atccagcttt
    42241 gtagttggga aaatccggtt gtgtttggtc ccaagctttt cgaatgacat ccacgatatg
    42301 ccaagattga gcgacttctt cccaatgaga gaagttcgtt ccatcaccat tcaacgcatc
    42361 taatagtaat ttttcgtaag cttctgggct attttcaacc atttctgcac tatttctaaa
    42421 ttccaatttg attggttccg tttcaaatcc ttgccctact tctttcccat tcaaggataa
    42481 agaaaatcct tcagttggct gaatatagat cgttagaaca ttaggtggaa gtgtcgtatc
    42541 gtcacatggt tcatcgacag atgttttgaa tacattaaca ggaacttgtt tgaatacgat
    42601 gttgatccga gtcccttttt cagtcaaacg tttgcctgta cgtacataga aaggaacacc
    42661 tgaccaacgg aagttatcga tagtgaattt gcctgcgacg aatgtttcag tctctgattg
    42721 agcatccact ttgtcttctt cgcgatagcc cttgaattgt acaccatcca attcaccttg
    42781 agcatattgc ccgcgaacga agttttctaa cacttcttct tcgttataaa tgcggatagc
    42841 tttcaatgct ttgatctttt ctgtacggat ttctttttcg gaaaatgcta ctggcggttc
    42901 cattgcaagt aatgctacaa cctgtaaaat atgattttgc accatgtctt taagtgcgcc
    42961 actatgatcg tagtagcccc cgcgatcttc tacaccgagg ttttcgccaa aagtaatttg
    43021 gatattgtcg atatagcgat tgttccattg agcctcaaaa atattattgg caaaacggat
    43081 agctgagatg ttttggatca tttcttttcc taaataatga tcaatcctga aaatatcttg
    43141 ttctgggaat acttctctga tttgctggtt caattcaaaa gcagactggt aatcagaacc
    43201 gaacggtttt tctatgatca aacgattgaa gccatttttt gtcataatat tttgtgattt
    43261 caaatgagaa acgatcgttc caaaaaattg aggtgccata gccaaataat agacacggtt
    43321 accgtttaat tgatagtgtc catctaatcg gtcagacaat tcttttaatg tctgataatg
    43381 cgttgaatca tttacatcat gggattgata gtaaaaatgg cttgcaaagg tagttgcttc
    43441 ttcatctgaa ggattcaatg cacggattgt ttctttgaca acttcacggt agtgctcatc
    43501 gctccaggga cggcgagcgg ttccgattac agcaaaatgc tcgcctaaat ttccttttct
    43561 gtaaaggcgg aacaaagacg ggtacaattt acgctgggct aggtcacctg taccgccgaa
    43621 tatcgtaaac aatacatttt tttcattaga catgtggata cactccttta tattttatcg
    43681 acaaaaatcg tgctggccgc cttaaagctg acggggattt tctttctatc attttggata
    43741 gtgatcggtc cttcataagc tgcgatgtca acgatctcat attcttcgtt gatattcagg
    43801 tcaatagtga ctaagtaatc caacaattct ttttcatcaa gcactcgtgc gatacgcact
    43861 tttgtaccga caggatagga ctccaatgtt tgtcggcgtt cttcatggac aacttcctct
    43921 tttttaggaa tcgatcctcc atgaggacaa tgttcaggat gattcaaata gttttctaaa
    43981 tgatctgcaa gatgttccga agtcacatgt tccaatactt cagcatcatc atggacttca
    44041 ttccagctat agtctaaatg ttcaactaaa aaaacttccc ataagcgatg tttgcgaatc
    44101 agactgctag ctttttgcag tccgcttgca gtcaattgta caccttgata aggggaatgt
    44161 tctacaagct cttctttcac aagtttagaa atcatttcac tgacagatgc agctgagaca
    44221 tctagactag atacgatttg tttattgttg actttcgttg tatctccacc tagttctaaa
    44281 atgattttca aataatcttc tcgatttggt gtcatattcg atcatccttt catggtaaaa
    44341 aaccatcatt agtaagtgta acaaaaaaaa cgttaattga ctatttttct aaataaaaaa
    44401 caaaggattt ttagacgttt ttacaacaaa aaacgaaaga tgatagagaa gactcattct
    44461 ttcgtttata aaggatatat atatacattg ggagggatct atttttcaga taacaactta
    44521 tatgaagtgt ctgcagattc gtcataaaga gtttgttcgg gataagaaaa gataagataa
    44581 aaaccatact gatcacgtac gactaaacga tattcatcta tttctaccac agatgtgcca
    44641 agagactgac cgttgatcaa aaacgtgtaa tcagatgtaa tctgtaattg ttgtttttgc
    44701 tggctatcac taaagaacca tgtaccttga tactttgaga gtccttctga cttttccgct
    44761 tgttttttct ttttcaagta aataaaactt gagagaacgg taatgagtga accaagaaaa
    44821 tagatcattt tttttatcac caaatcactc ctttatgaga aaataatcgc atagacatat
    44881 tctttcttct ttatttcatt gtaccgaata aaagctaaaa tttctctaag actttcgact
    44941 ggttttttta ctgtttttct acaaattatg ataggataca tagtaggaag aaaggtgaca
    45001 taatttgaag tatcagcaag tggaaatagc tttttttatt gaccgcccga atcggtttat
    45061 agcacattgt atgaaaaaag acggagaaat aattattgcg catgtcaaaa atacaggtag
    45121 aggaaaagag gtcctgatac caggcgctga agtggctatt gtatttgctc ctggacctaa
    45181 acggaaaacc gcctatgatc tgattgctgt aaaaaagaag ggtgactggt ttaatatcga
    45241 tagtcaattg cctaatcggc tggcaattga tggtatttta gacggcacga tccttttacc
    45301 aggattaact ggtccattta cggtatacaa gcgtgaagta acttatcttc actccaaatt
    45361 tgatatttat ttagagacgg tggtcggaca aaaagcattt gttgaagtca aaggtatgac
    45421 acttgaaaat aaagcgattg gtgcttttcc tgatgcgccc acactcagag gattgaaaca
    45481 tataggagaa ttaacgtatg ccgcacaaga tggttatgcc gcttatgtct tgtttattgc
    45541 tcagttcgaa catcttcatc tggcaacgat ccatgaagaa atgcaaccag cactagctga
    45601 tatggttcga catgcgcagc aaagcggagt tcaaatcctc gcctataatt gtcaagtatc
    45661 ggcagatgag gtaactgtca agcaggccat tccatttgat gtagatatcc cttttgaaga
    45721 tcctatacaa tagaaagaag gtaaaataat gatcaactta ggtattatcg gaacaaattg
    45781 gattactcat caatttgtcc aagcagcttt aagcacaaaa aaatatgaat tgacagcggt
    45841 atattctaga catttggaaa aagcacagga atttggttct cattatgaag gggatatcga
    45901 attcgcaaca gatttgaaga cttttttcaa tattactcat atggacacca tttatattgc
    45961 ttctccgaat agtcttcact ttagtcaagc taagcaagca attttggcag gaaaaaatgt
    46021 gatagttgaa aagccagctt tttcgacgcc aaaagaaatg gatgaaatca tccatttggc
    46081 aaatgaacac aatgtgtatt tttttgaagc agcaagaaat atccatgaat caggttttaa
    46141 aaagattgcc gattacttac cattaaaaga cgagataatc ggtgcaaatt tcagctatat
    46201 gaaatattct tcgcgctatg accaagtatt agatggagaa gaaccgaata tcttctcgac
    46261 tcatttctca ggtggtgcat tgatggattt aggtgtttac cttgtatatg cagctgttgc
    46321 ttggtttgga atgccaaaag aagtccatta tttcccaaga aagatttcta ctggtgtaga
    46381 tggtcttgga tgggggatct tacgttatga gaattttgat gtatcgatcc agccaggtaa
    46441 aatcggtgat tcttatttac cgtcagagat ttattttgac tcaggaacgc tagtgatgaa
    46501 tggagtcaat gcaattgaac aagcacaatt tcatgatcgc gcgcataaag aaatcattga
    46561 tttggcggta acagctgcag aaaatccaat ggcagatgaa gcagaggatt ttgccaatgt
    46621 catggctcat ccgaaagatc cagcttgggg attgttgtat gaagagtgga tcgagctagc
    46681 tagaaatgtg aaccaagtga tttatgattt aagaaaaaat ggcggcatca aattcgatgc
    46741 agataatgag gaagattttt aatgaacgaa tttgtacaag tatttcccga aaattggcag
    46801 aaaaaatatg aggataaagg gtttatctca ccttctctta ttcaacgagc agtttttcag
    46861 ccactaagta ataaacaaag tatagtagcg gtttctccta caggttcagg taaaacactg
    46921 gcttatcttt ggcctctact actaaacgtg gaaccaggtg aagcaagtgc gttggtcatt
    46981 tttgcttctt ctcaagaact agctattcaa gtagcagatg ttgcacgtga atggggaaaa
    47041 gacaaagagt tgaaagtcca atctttggtg ggcggagcca acgtcaaacg tcagattgag
    47101 ggtttgaagg aaaaaccaga aatcttgatt ggtacaccag gaagaatatt ggaattgatg
    47161 aaagcaaaaa aaataaaagc acatcaagtg aaaacaatgg tatttgatga agcagaccag
    47221 ctatttgacg ctgggaacag ccaaatcatt gatcaaattc ttcatcaagc tccaacagag
    47281 tatcagctag cttttttttc agcgacagca gatcgttccc ttgaaagcat tgaaaaaatc
    47341 actgggaaaa cgtttgagac aattgacgtg acagcagagg acgattctcg aaaaggactg
    47401 agacattact ttttacgtgt accgatacga aagaaagatg actacttgag acgtctcacg
    47461 catatagaag attttcatgg tctgattttc tttaatcaac tgactgaatt aggcgtaatg
    47521 gaagaaaaat tgctgtatag aggtgtaccg gtaggaagtc tggcctctga tcagaacaag
    47581 ctactccgaa aagcagcgct agaacaattc aaaaagaaaa tggtcagagc acttttgacc
    47641 acagatgtgg cggctagagg tttagatatt acaggtcttc cttatgtagt gaatgcagaa
    47701 gttccgttaa gtgaagaagc ttatttgcat cgttcgggaa gaactggtcg aatgggtaat
    47761 gaaggaatag taattacact cgtacaagat aataatctaa gagatttaaa acggctttta
    47821 cgtccatcaa atataacact tgaagagatt tttttatacg gaggtaagct gcaaactgag
    47881 cagccaacca aagaagatgc agctcctgca gtaaataaaa agtatgcgaa aactttttct
    47941 ggaaaggagc agaacccaga atataacaaa gaaaaaataa gaaaaaaagt taaaaataaa
    48001 tcaaaaaaag agagaaataa aggagcaagg cgcaaataag cgccttttta tgctatgatt
    48061 atgaaaacgg gaacaaaatt ggttgccaga ggaggggtta tgtgaaagaa cgtcaagaag
    48121 agatcttgca gctattgaca gaaaaccaac aaggattgac agcaagtgat gtagctgagc
    48181 gcttaactat cgatcgaagc aatgcaagcc gatatttaag tgaactatac aaggcccatc
    48241 atattgtaaa aaccgctggc cgaccagtcg tttactcttt gccaacggaa aagtcaaaat
    48301 ctgatgaagt gcatgtcgac tcttctacgc aagtgacttt tgaaacactc gttggagaaa
    48361 atgattcttt aaaagtcagc atacagcagg caaaagctgc gattctttat ccaccgcggg
    48421 ggttgcatac gattattttt ggagaaactg gtacagggaa gtcgatgttt gctgaatgta
    48481 tgtatcattt tgcaatcgat tcagagatgc tttctgcaga tgcgccattt gtttctttca
    48541 attgtgcgga ttatgctcaa aatccgcaac tgctctttgg acacatcttt gggatcaaaa
    48601 aaggggctta cacaggagca gctcaagata gtcccggtct aatagccaaa gcagacggcg
    48661 gtatattgtt tttagatgag atccaccgtt taccgccgga agggcaggaa atgctgttta
    48721 ctttcattga taaaggtatt taccgtccgc ttggagaaag tgcacaagta catgaagcat
    48781 ctgttcagat cattggggcg acgactgaat cttcagaaag tttcttatct acgttcaatc
    48841 gacggattcc tatggcaatc accttgccga atcttgcttc acgttcactg gatgagcgtt
    48901 atgaaatcat ctctcttttt atcaaacaag aagcgaatcg tttgaatcaa cgtatcgata
    48961 tcgaaaaaga agcgattctt gccttcatgc tttatgatgc ggaaggaaat atcggtcaag
    49021 tgaaacgaga cttgaaacta gtctgtgcaa aatctttttt acattaccgt actcatcatg
    49081 agaaaaagct aatcattcga aaagaagaac tttcccttca agtacaaaaa ggattactga
    49141 aaatcaagga aataccggaa cgtctcgacc gattcatgga cagcaaaagt cagtatttga
    49201 catttgaacc aggatttgct gatgttgtct ggtcacaaga tccagaacga aacatgcagg
    49261 tctataacga tattgaggaa aaagtcactt ctctttccga aaccggtgtg gagaacattg
    49321 atctagagac cctcatttca aaagatgtgg atgcttattt ccagacatat gtcaaagaat
    49381 tgactaaaag ttcgattccc aaagatcttt tgccagatga aatctggcgg ttaaccaatc
    49441 aattgtatga tgtggctgaa aaacggttag accgtattta taatgaaaaa gctcgttttg
    49501 cttttgcttt gcatctgcaa agtacattgg atcgtgtgag agaaggtcat atgatcgtcc
    49561 acccagattt gaataacgta cggaaaaatt ttaagaggga attccaggta gcaatcgatc
    49621 tttcaacgat cattgaagaa gaagaacaag ttgagattcc ttttgatgaa atcggcttta
    49681 ttagtatgtt tctttctatc aatctaggag aaagtgagcc tgttaaagaa aacaaagtag
    49741 atgttctcat attgatgcac ggcagacaga ctgcttcaag catgttggag atggcacaag
    49801 aactattagg aacaaaagta gggaaagctt ttaatatgcc actggttatg gaagttcaaa
    49861 caatgtatga agaagtgtta caatatgtca aaaactatca agagcatttg acgaatggcc
    49921 tactcttgtt aacagatatg ggatcattaa acaccttcag tgatttgatt tatgaagaga
    49981 ctggcattcg gacgaaagct atcacgatga caagtaccat gattgtgata gaagcgatac
    50041 ggatggcaag tgttggaaga agcttagaag atatttatca aaatatccag ctttcctttg
    50101 aatcgatcgt acgtgatcag ttcaaagcgg aaaagtctga aactttacag cgtaaaaaag
    50161 ccgtaatcgt gacatgcttt actggtgaag gagtagctgc caaattatat cagcgtatta
    50221 tgccagtgat taatcaaaat aaggtagaac tgatccagat gcagttttta gaacgtgaat
    50281 cattcaaaaa acacatcgat gccttattgg aagaatatga gatcaaagca attgcgggaa
    50341 cagttgatgt tgattatcaa aatatcccat ttttttcagc ctatgacgtt tttgatgatg
    50401 aaaaactaaa tattttaaag cgtatagctg atgatgagat cccgacagct aaaattgtcg
    50461 attcacttgc tggatcatta agcgatgtct tttctattga tgaactgatc cgttcattgc
    50521 aaaagacagt tcagcagatc cagaccgatt tgtcgattat cgtggaacct ggagtagata
    50581 ctggaatcgt tatccattta gccttcatgt tagacggatt gatcaaacaa gaaagccatc
    50641 ggcaatttga gaaactgtct attttctcaa aaatttatcg tttggaaatg gatatcgttc
    50701 gggcaaactt gatggcacta gaacgaaaat atcaggtaaa aattccagaa gatgatatcg
    50761 catttcttac acaaatgttt cttgaaaata aaataaaaaa atgaacacac taatcatact
    50821 gtttacacac taaacatctg tgtgcgcact ataaaaaaga gctaaaaagc atgaaaacgc
    50881 tatttcagct ctttttttta ttggcatgct tcttgcgtta tataaaagtg taaaaaaata
    50941 aaaggagtgt taaaaatggc aaaaaaaaca atcatgttag tttgttcagc agggatgagt
    51001 acgagtttat tggtcacaaa aatgcaaaaa gcagcagaag aaaaagggat ggaagccgat
    51061 atttttgcgg tctctgcctc agatgcagat aataatttag aatctaagaa tgtcgatgta
    51121 ttattattag gtcctcaagt acgtttcatg aaagctcaat ttgaacaaaa acttgcgcct
    51181 aaaggtattc cattagatgt catcaatatg caagactatg gcatgatgaa cggagaaaaa
    51241 gttcttgcac aagcagaaaa tctaatgaaa taaatcaagt atgcagttgg gggtataaca
    51301 acgtggaaga tcaacaaaat ctagaagcca tcatggggtt aatcatgttt ggcggtaatg
    51361 caaagagcga tgcaatggaa gcgattgcgg ctgctaaaat cggtgatttt gagttagcgg
    51421 ataggaaaat cgctgatgca gaagaatcac ttatacaagc gcatcatgca caaacagaca
    51481 tgttgacaca agaagcacaa ggaaatcata tgcaagtgac attattgact gttcacagtc
    51541 aagatcactt aatgacatct attgcgttta ctgatttagc aaaagaaatc atcgaacttt
    51601 atcgtcgcgt atacagcgaa taaatacaac ttcttttttg aacggaagaa gaaaaatttt
    51661 tgaacggatt ttttattttg ttataaggag aactctcttt atataaaaaa cttataggag
    51721 gaagtaaaaa atgaacggac tatcaagttg gatggagaaa tacatcctgc cggttgccgc
    51781 aaaaatcgga gcgcaaaaac atttagttgc tttgcgtgat gcttttatcg gcacactgcc
    51841 cgcaacaatg gcgggatcag tcgctgtaat gatcaatgca attattcgtg atttaccgca
    51901 acagtttaac agtacctatg ctgacagttt agcagcagac aaaggaatct ttgccgtatt
    51961 gaatgtcatc atcggaatca atggttttgt ctggaacggt acactagcaa tcgccggatt
    52021 gatctttgcc ttttcttggg ggtataatct tgcccgagct tatggagtaa atgatctagc
    52081 tggggggatc gttggtttag ctaccttgat tcaaggtatt tcctttggtc cagcattatc
    52141 agcagcatta gatgtgaatg ttccttcaaa tgtcgcagat gcaatcaata gttctgagat
    52201 tggtgcaacg attgcagatg gcacactgtc agttggatta tggggttggc taaaactaga
    52261 tcatttgaat ggaaacgctt attttacagt tatgatcatg ggagctattt cagtcattat
    52321 tttttgtaaa ttgatgcttg ccaacattac gatcaaaatg cctgattcag taccaccagc
    52381 agtatctaaa gcatttgcag ccattttacc agcgacgatc gctttatacg tcattgctat
    52441 tatcaattat atcgtaggtc gtgtagctga tgggcaactg atcattgatt tggtgcaaaa
    52501 atatattgca gagccattcc taggattatc tcaagggttg ggagcagtat tgatcgtcac
    52561 agtatttgtt caagtattct ggttctttgg tattcatgga ccaaatgtat tggcaccagt
    52621 gctagaggga atctggggac aagcacaact aatcaatatt gatattttcc aaaaaggtta
    52681 taacggaaaa actggtacac cagccgtgtt agatgcaatc gaagatggaa aagcttatat
    52741 gtgggtccgc ggatcgttcg atgcttttgc atggtttggc ggatcaggcg gaacgatcgt
    52801 cttactgata gctatcttga ttttctctaa acgtgcagat tatctaacag tagctaaatt
    52861 atccattggg cctggtatct tcaatatcaa cgaaccagtg atgtttggtc tgccaatcgt
    52921 attgaatgca atcatgttta tcccattctt gattgctcca gtagtagcaa cagcaattgg
    52981 atggacagct acttatcttg gcctagtcgc tccggtatcg cagcaagtca catgggtagt
    53041 accgccgttc ttattgtcat tcttagcaac aggagcggat tggcgggcac cgatcgtaac
    53101 attagtatgt atggtcgtga ctttcttgat ttgggcacca tttgtcatct ctgcaaacaa
    53161 aatggaccct gccgcaggcg aacaacaata agatgaacgt gaggagcggg acgctttaag
    53221 tttcgttcct cataatgaat tttcgaggag gaactgaaat gattacaatt gccagtgcaa
    53281 tgcaacaaga tgaaatcaaa gaattgttag aaggatacaa tgaagaagga atgactttta
    53341 catttaaaga aaaacaagga atcaagctgt tctttgaaac aagtgcagaa gatccggaag
    53401 ttgcggctaa aaaagcaaag gaactaatca aagcacagcc ttggggaaca gtcctttatt
    53461 ttcaatcaac agctgtttag aaaatggttt aaaaagatag gatggttgag atgataaaaa
    53521 acggtttatt tttatgtagt attggttctt tgatcgtgtt gtatagtttg aatccacatt
    53581 cgcaaaggta tgatttgtat agtatggtca caggtctttt tctaacagga ttaggaatct
    53641 atttcttcat gaaggggaaa aaaagagaag aagcaaagga gaaaaataac taatggaaat
    53701 cacgaaaaaa ttaaatattc cagcatcgtt tttttacgat aaagttatgg actctgtcct
    53761 tttcgatgta cgtaaagcga ccggcaaatc agtaactaga aaacagctga aaaatttgga
    53821 gtacgtcaaa caattctcgc aaaataaccg ggctcgcata aaaatcgaag aagtcattga
    53881 aaaccagtct tataagtttc gtacatcgac aacgaagaat gaattcgtcg ttcattatca
    53941 aatcaaacca ttggacgatt cgacctgtga ggttcattac acagaaaaaa tggagtctta
    54001 tggcatgctt caaaagttga atgatatgct tttaggaaca atcttgatgt attttaaacg
    54061 gagacgtttc aaaaaaatgc tagatatgat cgaagcaacg tattaaatca atgaaacatg
    54121 gtactattta gttattgaaa aatgaagtaa gctagaagga atttttcata ggaagataga
    54181 tctttcctgc gaatcctcac tagctttttt gtaggaaggg gcagcaaaat gacaaacaaa
    54241 gtaagagagc taggtgtatc ttcgattgag gaaatgtttg atttagccac ttatgcattt
    54301 aatggggcag atacacctga aaggcgagaa cgttttcgta cacttgcgga gaattcttgg
    54361 aattacggat tttttgatga ggaggatcgg ctaacaagtc aagtcatggc gacccctttt
    54421 ccagtgaatt tttacggaca agagtaccta atggccggca ttggctatgt tgcttcttat
    54481 ccagaagcaa ggggacaagg cgggatcaat cagatcatgg aaaagatcct tgaagattgc
    54541 cgtgatcgta aagtaagctt atcttatctg gcgccattct cctatccctt ctatcggcgc
    54601 tatggctatg aacaatcatt tgataaaatc agttatcaac taaacagtcg tgatgtgccg
    54661 tttatcaaaa aaaaatctgg aaaaataaag cgtatggatt ttgaagatgc aaaagctgca
    54721 atcagaagaa tttatgaaca gatgccggaa aaccaacgag ctggtctgaa gcgcgaagac
    54781 tggtggtata cgtataaatt caagcaaaaa ggcaattacc agtttgcttt gcattttgat
    54841 gataatgagg aagcaacggg atatatcgtt tatcagcttg caacgtcttc ctttattatt
    54901 gcggagtggg gatttttgga tcatgatgct ttttgcagcc ttgttcgctt cgtaagttct
    54961 cacaatggtg cttttgaaac atttgaatat tcatgcggct acggcggtaa tgatcaaaat
    55021 tatctattag aaaatccatt tgcttctgta atgatcacac cttatatgat ggcgaggatc
    55081 gtagatattt ctttgttttt ggaaaattat ccatttaaaa agagacaagc tgcatttgcc
    55141 ctacaaatag aagaagatca ttatgcgaaa tggaatgaag gaatcgtgga agtaacaatc
    55201 gaaaatggaa aaaatcatct ctcaaaagta gaacaaacaa aactcccaat cgttcgagga
    55261 agtatccaac atatcacgca gctattatta gggtatcgta aagtggaaga gttggtattc
    55321 caagaaagaa tacaggtgac aaaagaatat gaagaaacgt taagctcaat cttgccacag
    55381 caacagccaa ttcttaatga ctatttttga taaaaaacgg gtgatgacaa tatttttgtc
    55441 accacccttt tgtttttcat ttggcatttg aaggaaaatg ttaaagtaaa tcctcttttt
    55501 tcgtaaattt gaattttttg ttttcttttg ttttagggtt ttcttttttg tggtcttgga
    55561 ttgcttcttt cgtaatcttt tcccgatttt ttttagatga atctaagcgt tctgcgtata
    55621 ctttttcttt tggcttatca ttcattggaa aggacctccc tacattattt cattctacct
    55681 ctagtttatc atctgttaag gactagtgga aacgttttgc ctaacttata agctgatttt
    55741 tttagcagat aagcttgcaa gtaaaaaaca aacaagctac aattgattta ttgaaattgt
    55801 tcctgtagct cagtaggata gagcaatcgc ctcctaagcg ataggtcgct ggttcaattc
    55861 cagtcaggaa cgtacaaata acccctgtat cctttgcggt acagggggtt attttgtata
    55921 agtagacatt gtagtttcta aactgctatg tcctaaacgt ttcgatacgc taagtatatt
    55981 tactccttga taaagtaaaa tagatgcatg cgtatgtctt agtccatcaa taaacagtcg
    56041 aagagaaaat agggaaaaat tgattactaa agaaaaactt actaggtcga cggtgtagtt
    56101 gattttcata cttcaataga ttcgaattaa acgatttcga ttggcttata ccagtcctat
    56161 ccaacgaaag atatatcgtt cttaactcta gcggtataac ttgaagcttt acgtaaagcc
    56221 aatgggaatg aactggagat gactttttat tatttttagt aatagctgat gggttaatac
    56281 ttacaacttt ccttttcaaa gtaccatata aaaaaacggt ggggttgttt agcgaaataa
    56341 aggatctaag ccaatagctt agatccttta ttctatgctt tatattattt tttgcatgtg
    56401 tgcgaaagta tactcaagcc caatcgccat ttcggaaaat cggtactgta gagccatctt
    56461 cacggattcc gtcgatatcc atcttgtcag atcctaccat gaaatctacg tgggtttgac
    56521 ttctattcaa tccagcttct gctaattctt catcggacat ttctgtaccg cctttcacac
    56581 tgaaggcata agcagaacct agtgctaagt gattcgatgc gttttcatca aataatgtat
    56641 tgaaaaagat gatgccagat tgagaaatag gtgaagggtc aggtacaagt gcgacttctc
    56701 ctaaacgacg cgcaccttca tctgtatcaa gcagttttgc taagacatct tctccttgtt
    56761 cggcagaaaa atcaacaact tttccatctt taaaagtaaa tttcataccc gagatgatgg
    56821 tgccagcata actcagtggc tttgtacttg aaatgtaacc atctactcga tgactgtcag
    56881 gtgctgtgaa cacttcttcc gtcggcatat ttgccatgaa tttttctcca cgagcattat
    56941 agcttccagc gccttcccaa agatggtttt taggcaatcc gataatgata tctgtaccgg
    57001 gagcagtata gtgaagggca gaaaattgtt ctcgattcaa ttcttctgct ttttttgcta
    57061 atttttcatc atgcttcttc catgctaaga cagggtcttc ttcatagaca cgagtcgttt
    57121 tgaaaatctg atcccataat gcctcaactt gtttttcttc tggcagttct gggaagactt
    57181 ttgctgccca ttgtttacca gccgcagcca cgacagtcca actgacttta tttgcttgag
    57241 ttgccttgcg taaattcatt agtgctttgc cattcgctga ttgataagac gctactcgat
    57301 ggctatctac accagcaaat gcatcgggat cggcagaaac aacgctgatc ctgcttgctc
    57361 ctttttcaag ccattcatcc gcttgatcga ttttagattg tggtacattc tcaatacgat
    57421 ccgttgcagc atgtaaaaga aattctcttt ggatctggtc gtcagtccat tgaacgataa
    57481 cctcagcggc tcctagttta taagcttctt gtgtgatcaa tcgagcaagg ggtgcctgtt
    57541 ccacgctgat ctgtaaaaca actgtgtgtc ctttttctgt ggctacgcca gtttctgcaa
    57601 ttaagcgtgc atattttttt agaagttcat taaaatcaga taacataata aaaattcctc
    57661 ctcaccattt tttctggtaa ctattagcat gataccattt aattatgatt caaacaatga
    57721 ggctttaaat aaaaaaagga ggttattttt ttaaggttaa gtttcatgat atatgttact
    57781 acttgctatt tcagcttgtg aagaaaatca aaaactaatt ttgcatatca aaaaaacatg
    57841 ttacaatgaa attaatcaat ggtggaagcg ttataaaaaa attaaggaga ttaaaaaata
    57901 tggcaagaaa aaagacgatt actagagaac agattttggc agctgcttat gaagtagctg
    57961 ccaccgatgg atttacacga tttactgcga gaaacatcgc gaacaaaatg aattgttcca
    58021 cgcaaccgat ttatcttgag tttaaaaata tggatgactt gagacaagct ctttttgagc
    58081 agatctatga tcatttacaa tatgaagtgt tcactgttga gcatacaggg aatacgatta
    58141 tcgatcttgc ttttaattat atccattttg caagaagaga gaagaagttg tatcgttcac
    58201 tgtacttaga agaatatggt ggaggaaaag agatgcagaa tttctcttat acttactttg
    58261 tgaatacagt gaaacgcgat ccagcttatg tgaatctttc agaagagcag atcgaatctt
    58321 tgtataatgg gacatggatc atagctactg ggatcgcagc tttgatgtct tcaagcatca
    58381 tccatccaac tgatgaacag attgaaaaga tgatccaaga cagtatagat gctatcttga
    58441 aattcaaaga accaatcgaa atcgattgaa tatactcaaa agttccacaa atcagtaggt
    58501 aacaagagat gtgtcaaaat aaggaaaagt tcgtttttct tacagcgtat gcatttttaa
    58561 ctcccgaaga actcttccat gaatgcaatg aataaaagag ccatacagat tgaataaatc
    58621 tggatggctc ttttattgca agtatattaa atttttgcga ctagttcttt agcgaaagct
    58681 tctaaatttt cgatatcttc ttcttcagca ttcagatcca ctttaacatt ttcggctcct
    58741 tttgatgcgc ctgtttttgc aaaagcagca tcgaaatcat ccaccgattt gcagaattca
    58801 tcgtaaaaag tatcaccaga tccgcagaca ccgtaaattt ttcccaatag atccaattct
    58861 tgcaagtctt cataaaagtc tacgatctca tcaggcagat cgccatcatc gtatgtataa
    58921 gtagctacta cgcaaatatc tgcctcctcg aattcatctg catctacttg ggtacattcg
    58981 ttgatttcga cttcgatatc cagattttca aatgcttctg caacaatatc ggcgatttct
    59041 tcagtgtttc ctgtcatgct agcatatacg atttttgcta aagccatgat gtgcctcctc
    59101 gtttataatt atttaacaat tatgaattat accaaaacat cattgaaaag aaaataaaac
    59161 ctaaagacac ctggggaatg tcatttggct aaatgtatgc cgctatgtta aaatgagagg
    59221 gatttgtaaa aaggagacga aaatatgatt actttaaaat cagcacgtga aattgaaatg
    59281 atggcagaat ctggagcttt attagcagat gtacataaaa atctgcgtga ttttataaaa
    59341 ccaggaatca caagttggga tattgaggta tttgtcagaa actatatcga gagtcatggc
    59401 ggaattgctg cgcaaattgg ctttgaaggg tatgaatatg cgacttgtat cagtataaat
    59461 gatgaaattt gtcatggatt ccctcgtaaa aagcctttga aaaacggtga tttggtaaaa
    59521 gtcgatatgt gtatcgattt gaaaggcggc atttctgatt cttgttgggc ctatgtagtt
    59581 ggagaatcta cacctgagat cgaccgattg atggaagtaa cgaagaaagc tttgtacatc
    59641 ggtattgagc aagcacaagt agggaatcgg attggtgaca tcggtcatgc tatccaaact
    59701 tatgtagaag gcgaaaatct agcgatcgtt cgtgatttta ttggtcatgg cgttggtcct
    59761 acgattcatg aagaaccagc agttcctcat tacggagaag ctggaaaagg gttgcggttg
    59821 aaagaaggca tggttatcac gatcgaacct atggttaata ccggaacttg gaaaatgaaa
    59881 atggatccta acggctggac tgcgtataca agagacggcg gactttcttg ccaatatgaa
    59941 catacattgg ctattactaa agatggtcca agaattttga catcacaagg agaagaaggc
    60001 acttattgat ctatccagtc aataggtacg ggagaggtac atgaaagttt ggaacaaaat
    60061 aaaacaaaat gaaaatctga tgcgctttat tgagacgact caaaagcgca tcactgattc
    60121 agaaatgagt acgacctctg tcgtcgttgc ttattattta ctcttgtctt tatttccatt
    60181 gattattgct tttggtaata ttttaccgtt tctccacatc gatcaagaga ctgtactgac
    60241 ctatttacga gaagtgattc ctgagaccgt ttaccagttt atcggtcctg caatcaaaga
    60301 ccttttgaca caaagttcag gaggcttgtt atccgtttct gcattagcgg ctttatggtc
    60361 tgcaagtcaa agtatcaatg ctttgcaaat tgcgatgaat aaagcgtatg gcgtagaaaa
    60421 tagaaaaaat tttttgatcg tccgtttctt ctcactaatt gtcattgtct tgttcatgat
    60481 tgctattagt ggggtaacta tcgttcttgg gttgggacag ctgattttgg atgctattca
    60541 gccaatcgta caaatacccg tgaactttat cgatcagttc caaactttga agtggccaat
    60601 cacattggta gctttatttg tcatcatgtt cttgatttat ttaattgtcc ctaatgctca
    60661 gttgaagttg aagacgatca ttccgggcac gatcttcgct actgtcggct ggatgctgtt
    60721 atcacaagtg tttagtatct atgctaggta ttttgcaacg aggatcagcg gttatcagat
    60781 cataggaagt tttattgtac tcatgctttg gcttaatttt gctgctacga tcatcatttt
    60841 gggcggaatc atcaatgcag ttgttcaaga atacgtgacg ggtcatcaaa tcaaaaaacg
    60901 tcgagatcca agccgaaaat ggttcaataa attgaaaact aaattttctc ataaaaaaaa
    60961 gtagaaacaa gagttcttat tgtaaattta tatcagtaat ttataataat tatgactctt
    61021 aattaaagta ggtgcccata tgcttgtttc ttttagtatg gttataagat tttttctgac
    61081 aattttatta tcactgatat taacacctgt attcaaaatc atttcagtac aaacaggtat
    61141 ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca atgccttcag cgggcggact
    61201 gcctatcttt atttcatttg ttatatcgac tttattctta ttccgtaaaa ttatccctca
    61261 atcgtatatt gtaccgatct tgattgcttc tttagtaatc atagtcacag gagtgctcga
    61321 tgataaatat gagctgacac ctaaacaaaa aagtataggg atcttgattg cttctcttat
    61381 tatttatttt gtagcagata tacgtattga ttccttcacg cttcctttta ttggatatat
    61441 ccaactaggc tggcttagtt ttcccgtaac gattttttgg atcttcggta tcacgaatgc
    61501 ggtcaatctg attgacggtt tggatgggct ggcggcaggg atttcattga tcggtttaat
    61561 tacgatagga atcattggat attttttcct ccatgcttct acagtgtata ttccagttgt
    61621 tattttctgt cttgtagcaa gtattatcgg tttttttcct tacaattttt atccggcaaa
    61681 gatttattta ggcgatacag gagctctatt cctagggttt atgatggccg tcctttcact
    61741 acaagggctg aagaacgtga cttttgtttc atcgatttct ttgctgatcg tcatgggagt
    61801 gccggtaaca gacacgtttt ttgctatcat taggagaaaa gcaaaccgtg tttctttttc
    61861 tacagcagat aaaaaacatc ttcatcaccg actaatcagt ttaggcttta ctcataaagg
    61921 tgctgtcctg acgatttatg cgatggcttt gatgttttct ttcacagcta tggtcatgaa
    61981 ttatactgga agaatcggaa cgatcgtatt gattattgcc atgttgtttg ctgcaatttt
    62041 attatttgaa ttgattggtc tgatcaatga gaaacatcag tttattttaa aaacattgcg
    62101 atttttaggg aataaagagt accgtacgca agtaaaacag aaatatttga agaaatggaa
    62161 ccgtcatata gatgaataac aaattaaacc agccgatcct tattagtatt gtgacggcaa
    62221 acagtgataa aatttttcgg acactagata attttatttc aactgtaaaa gatgaaacag
    62281 cagtaaaaat ccgaattttt gacaacaatt cacttcccga gtacaaaaaa agactaacag
    62341 agtataggaa atatccctac atcgatatct attttcatga tgaaaattcc ggatttggtt
    62401 atggacataa tcacaatctg atagctagcg attctcgcta tggcattatt tgtaacccag
    62461 atattttagt ggatgaagag acagttacag cattggtctt gttattgaaa gaacatccgg
    62521 aatgtgcgat gttagcacct aagattctta atgaagatgg aacaactcag cacctcatcc
    62581 gtgagcagct ggctgttttt gattacgttt tgcgctttgt gcctttcaaa tgggtcaaaa
    62641 aaaagtttga caaacgactg gctgtgtttg aatgccgagg attgcctact gatgctaata
    62701 gttatgtacg gatgatctca ggtagtttta tggtagctga tattgataaa tttaaagaga
    62761 taaaggggtt tgatgagcgt ttcttcatgt actttgaaga caacgacttg tgtttgagtt
    62821 ttgaaaaagc aggttacaag ttattgtaca caccctttta tgcagttatc catttttacg
    62881 ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt tttgacttct atgatgaaat
    62941 ttttcaataa gtgggggtgg cgttttttct gatgaaacca gaaatattag tagtcgttgt
    63001 gctttatcag caactattca gtcaatctcc agcttatgga ccattaagca aagcacttag
    63061 cgaaaagcaa attcagctta ttatttacga taatagtcct caaaggcagc aaaatgagct
    63121 gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa aatcctggtt tagcggtggc
    63181 ttataatttt gcgttgtctc aagcagatga aggaacacgt tgtctcgtca ctctggatca
    63241 ggatacgagg ctagtcgacg attattttga actattgcgt aaagtaacct ttacagatga
    63301 atgtgttgct gcagttccga tgattttttc tgggagccga caagtttctc ccctatattc
    63361 agatcgttat atcaatcgta cagctcaagc agtagaagtt gaaggcccaa cagctgaacg
    63421 aatcatggca atcaattcag gtgttgcctg gtctgtcaaa tttctaaaaa agattggcgg
    63481 gtttaatcct gctttttctt tagatttttt ggatcattgg ctgttttgga aagtggatca
    63541 gttggaaaaa actgtggaga tccttcctgt acgaatggaa catgatcttt cggttttaga
    63601 ctatgaaaaa gtttcaagta atcgataccg ttctatttta caagcagaaa atcgatttta
    63661 tcatgaatat gatcaaaggc atttatccag tcaccgacga caattattgt taagaacagc
    63721 taaacagttc ttgaccgtca aaaaccggca tatctggcgg atgactttgc gctcatatgt
    63781 taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat agctaccttt aatggaggca
    63841 gatatttaag agagcagtta gatagtattt tatctcagct ttcagcagaa gatgaagtag
    63901 tcatttctga tgatgggtca gtagatgata catgggatat attaactgaa tacgcagaaa
    63961 aagataagcg aatccagctt ttttcggggc ctcgtcaagg attgatcgct aattttggtt
    64021 atgcgatcca gcagacgaaa ggagatctaa tctttttggc agaccaagat gatgtttggt
    64081 tggagacaaa agtgaaaaag atcactgact attttgagca gaatccggat cagctagtag
    64141 tagtttctga tttaatcatt gtggacagcg agctgcaaga gatccatgat tcgtattttt
    64201 cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat aagaagtcac tatattggtg
    64261 ctggtatggc tttccggtct tctttaaaac ccgatatttt gccgatcccg tcagaagtgc
    64321 cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa gactgggttc ctaagagaac
    64381 cgttaactct gtaccgaaga catgatttaa acgcgagtga gattgaaaca cattctaaat
    64441 tacggcaaaa aatttcttgg cgtgttcatc tgattacggc gttgatcaaa cgaaaatggt
    64501 ttaaacgttg ataaaagatg tttaaatcct taatatttcc atgacaaata taacaattga
    64561 tgagataata acaaagtgaa atttgaaatc aaaaaggaga gcagatatcc atgaagggaa
    64621 tcattcttgc tgggggcagc ggaacacgtc tgtacccttt aacaaaggca acatcgaaac
    64681 aattgatgcc gatttatgac aaaccaatga tttattatcc aatgtctact ctgatgttgg
    64741 cgggaatcaa agaaattctg attatttcaa cgccacaaga tacaccacgt ttcaaggaat
    64801 tatttggaaa cggaaatgat ttaggactgc agatcgaata tgcagtacaa gaaagtccag
    64861 atggattggc acaagcgttt atcattggag aagaatttat tggagatgat agtgtctgct
    64921 tggtattagg ggacaatatt tactatggtg gcggtctgtc taaaatgttg caacgagcag
    64981 cttcaaaaga tacaggcgcg acagtatttg gctatcatgt caatgatcca gaacgctttg
    65041 gtgtagtaga atttgatgag aatatgcaag ctttgtcgat tgaagaaaag cctgctcagc
    65101 caaaatcaaa ttacgctgta actggccttt atttttatga caatgaggta atttctatcg
    65161 ctaaaggtat caaaccttca gaacgtggag aactagagat tacggatgtc aataaagcat
    65221 atttggataa aggaaaacta tccgtagaac ttatgggacg cggatttgct tggcttgata
    65281 caggaacaca tgaatcattg cttgaagcat ctacctttat cgaaacaatt gaaaaacgtc
    65341 agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg tatgggctac atcgataagg
    65401 aacaattgct ggcccttgca cagccattga aaaaaaatca atacggtcaa tatttattga
    65461 atttggccgc tgaataagga gtccttacag atgaaagtaa cagatacaaa attaacagat
    65521 gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg gtttcttcac agaaagttat
    65581 tcaaaagcaa aatttgcaga acatggattg aaatatgact ttgttcaaga caaccattca
    65641 ctatcagctg aagctggtgt ccttcggggg cttcatttcc aaaaaggaga agctgcacag
    65701 acaaaattga ttcgggtagt cactggagca gttttagatg tagtagtgga tatccgcaaa
    65761 ggtagcccga cttatggtca atgggacgga tttatcttat ctgaacataa tcatcgacag
    65821 ttgcttgtac ctaaaggata tgcccatgga ttcgttactt tgacaccaaa tgtgaacttc
    65881 ctttataagt gtgataatta ctataatgca gaagcagatg ggggcatcgc atttgatgat
    65941 ccagatttag cgattgattg gccaattgat ccatcaagag cgattatgtc ggaaaaagat
    66001 caccgtcatc cgacattaaa agaatttgaa gcagaaaatc catttgttta cggagaaatc
    66061 taagaattaa ggagaaattt tcttatgaaa aacatcattg ttaccggagg tgccggattc
    66121 atcggctcta atttcgttca ttacgtggta aacaatcatc cagaagtgca tgtcactgtt
    66181 ttggataaac tgacttatgc aggaaacaaa gagaacttgg ccggacttcc tagcgatcgc
    66241 gtagaattgg tcgtaggaga tgttgcagat gcagaattag tggaccgtct agtaaaagaa
    66301 gcggacgcag ttgttcatta cgcggcagaa tcccataacg ataattcatt aaaagatcct
    66361 ttcccatttg tacaaacgaa tatcattggt acgtatacac ttttagaagc ttgccgcaag
    66421 tatgatgtac gctatcatca cgtatctact gacgaggttt acggcgatct tccattacgt
    66481 gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat tcactgcgga aacaccatat
    66541 aatccttcaa gtccatattc ttctacaaaa gctggttcag atctgttagt aaaagcatgg
    66601 gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt caaacaacta tggtccttat
    66661 cagcatattg aaaaatttat tcctcgccaa gtaacgagta tcttaagcgg tattcgtcca
    66721 aaattatatg gcgaaggaaa gaatgttcgt gactggatcc atacgaatga tcattcttca
    66781 gcagtgtggc tgattttgac gaaaggcaga attggcgaaa cctatctgat cggtgcagac
    66841 ggtgaagaag ataataagac cgtgatggaa ttgatcttag aaatgatggg ccaaccaaaa
    66901 gacgcatacg accatgtaaa cgaccgcgca gggcacgatt tgcgttatgc aatcgattcg
    66961 acaaaattgc gagaagagct aggttggcag cctgagttta cgaacttccg tgatgggttg
    67021 gctgacacga tcaaatggta cgaagaacat gaagactggt ggaaaaaaga aaaagaggcc
    67081 gttgaagcag catatgccaa aaatggacaa taatacagag gaaatttcac tgtattaatg
    67141 gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt taaaataaaa atcaaggagc
    67201 ggataaccat atgtttttat taactggagg aaatggacaa ttaggtacag aattgcgcca
    67261 tttattagat gaaaaaaatc tgccatatgt ttcaacagat gcaaaagact tggatatcac
    67321 agatgctgag aaaacaatgg cttatattac agaattaaaa cccgatgtta ttttccattg
    67381 cgcagcttac acagcagtag ataaagcaga agaagaagca aaagaattag atgagaaaat
    67441 caatgtcgat ggcacaagaa atgtagcact tgcagcaaaa gctgtgaatg cacaattcgt
    67501 ctatatcagt acagactatg ttttcgatgg aaaaaacaaa aatgtagaat acgaagtaga
    67561 cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa ttattaggcg aaaaagcagt
    67621 agaagagatt ttagaagact attatatcat acgaacttct tgggttttcg ggatctatgg
    67681 acacaatttc gtcttcacga tgcaacgcct agcggaaacc cgcgacaaac tgactgtagt
    67741 aaatgaccag tttgggcgac caacttggac acgtactttg gcagaattta tggtatatgt
    67801 catcgaagaa aaagcaccat ttggtattta tcatttgtcg aacgaaaata gctgttcttg
    67861 gtatgagttc gcaaaagaaa tattgaaaga tacagatgta gaagttgcac ctgttacgtc
    67921 agaagaattt ccgcaaaaag caacacgtcc gcagtattca gtcatgagcc tgaaaaagac
    67981 agaagcgtta ggttttgtca taccaacttg gcaagaagca cttgcgcaaa tgctggaagc
    68041 tgccaaaaaa atgaataagt aatttccttt ttatcaaata gaatttggag catgatatgg
    68101 aaaaacaaac aagaagtgca cgacgaaaag aaaagccaaa agcgaatcag gcagattcga
    68161 atttggtgct tgacctgttt ctaaaactcc gctatcttat tggcgtttta gtcatcgtgg
    68221 tcatcgttac ttttaattta aacggaagtt cacttggtgt ttgggataaa tatgtgtcgc
    68281 aaagagacga tgggaaaaaa actgatgtga tttttggaca gaatcgggaa gtgcggtcag
    68341 acgaatggct ggtgcagaca cctttttacc tctcacaagc tgaagaggac ttttcgttgg
    68401 tgaacgagga ttattcatta aacggacaaa acatgatcat tgcgtataat tctcctgtaa
    68461 aggatattac ggttatcgga aaaccattca actggggatt ctttttcctc ggaagagatc
    68521 gaggactttc cttttattgg gcgatgaaat tagtcgtcat ggtcttgctt ggattcgaag
    68581 tactgatgat attaacgaag aggaaaaaag ctctatcgct aatcggtgca tttgcgctga
    68641 cattttctcc agcagtccag tggtggttca tgcaacatgt gggcgatttg attttcttta
    68701 ctttgggact gatgattgct ttttatcatt atttctacaa tcatgataaa aaatggctac
    68761 gaacgttgat gatgcttttg gtggttattt tcggtattgg gtttatttta gtgatttacc
    68821 cagcccatca agtgatgctg gcgtacttgc tgatttttta ttttgttggc ctgcttattt
    68881 actatagcaa gaaagtttca tgggatctgt tggatgtagt gttgattgga ggggcagttt
    68941 tatttattgg cggagtcatg gttcatttct ggctaacgtc aaaagacgca ttgttagctt
    69001 ctttgaatac cttatatcca ggaaaacggg taagtactgg aggaaagtgg acgattggcg
    69061 aatttttttc tttccttaca aattggaaaa ttccttttga agatatcaac tattcgaata
    69121 actctgaagt ggccctgttc tatcactttt ttccaactgt attcctagca agtccatttg
    69181 tgttatttgg caaaaaagat agcgaacaaa agttactggg acgtattttg atgatttttt
    69241 gtctgttttc tatcttttgg attaccgttg ggttgccaaa atggctagca gaaatcactc
    69301 tgctgtctta tgttcctcca ttaagagcca tccttacttt tagttttgcg gcttgtttat
    69361 tatcgatctg gtttatcgct tatatttgga gagaagatgt tattcctatt tggtataaat
    69421 tcattttgtt ggcagtaaat gcatggtctt atttctatgc gattacgcat tcgaaaatgg
    69481 ataattattt ttcggatttt gaaaccatcg cagttgctgt gttgggaaca gtgattttag
    69541 cttttgcatt atttggctgg agacgcttgt tttacctcgc ttttgtcgcc ttagttatcg
    69601 tatctggctt tttcgtcaat ccagtcgtag aaggtacagg agcgattttt gaaaaaacac
    69661 tggcaaaaga aatccaaaaa atcgatcaac aagatcctgg taaagtttgg ttgtctgaag
    69721 atgaattata taacttcacc ccaacattgg gagtgaaatc cttcaataca gtacgctttt
    69781 atccagatat agctgcatgg aagaaaatcg atccgaaaga agaatacgag aagtattata
    69841 atcggtatgc tcatacaaga gcttttatcg ctaaggaaga tacaaagttc attttagatc
    69901 gtccagatat gttttcggtc acgttgaatt ttgaagacgc agaaaaatta gggatcgact
    69961 atgtgatcag taaacgacca ttaactgatt acaaccaatt atatgaagcg cagttcacgc
    70021 agctatatgg accggataaa gacggttata tgatttttaa agtagaatat ccggattatc
    70081 cagatgtacc acaaacacaa actcaggaaa atcagctagt cgtacagtaa taggctagct
    70141 gagaataatc ctgaaatatt agtagaaagg agagtgaaga taattcaagc aatcgtacaa
    70201 aaatttgtca acaaaatgag tgtcggtttc ttgcttttgt tgctgacgct agtctttttt
    70261 gtttggacag caggggtagg ttttccagca actttgttta tatataacaa tagttcatta
    70321 cttatcgctt ttagtgtggc tattttgctc attttaaatg tttataaagc aaaaggcgtc
    70381 gattttcttt atctaggtgt tgcgcttgcc cttttcattt tcttttctta ctttcgggaa
    70441 ttaagaaatg agtctttatt tggagactta ctgtttcctt tggttatttt attttgttta
    70501 gtaattaaat ggatcgagtg gacaaaatgg gatcgcggta tttatctgat tgtctttacg
    70561 gtcttcctcg gaatcacgtt atatcgtgta tttacagaga tccaagtacc agaaggacaa
    70621 agcatctggg ctccaggcaa ttcgctttct gatatttgga tcaatacgaa tacaatcgga
    70681 agttctttga tgactcttgc tttattgatc agtggatttg ccagttcttt tgaacgatgg
    70741 tatgttcgaa tcatcggtgg gatagcagtc gttgcagcct ttttaggtat ttgggtctgc
    70801 caatctagag gtgcattagt cgcgttgatt gtttttgcga tattggatct tttacctaaa
    70861 tcgttgatgc gtgtcattcg tgcgccattt attgcctaca cggttacgat tcttttagct
    70921 ttgccgattt cttatctggc ggctgtctct gaaaaagtca atttgtttac cgatcgagaa
    70981 gatatttggc ataaattcta tcagacgcta ggagaaaaat ctgaacaagt tttactagga
    71041 atgaaaacat ttatcttcca gcgaggaaac caatttttag gaaaccacaa tagttataat
    71101 tctattttga atatctatgg attgatagga tttgggattg ctgctttgct gcttatcctt
    71161 tttattggtc gcttaacgtt gaaagcagat ttatccaacg ggcagatgac ttttatctgg
    71221 gccttttttg cggtgatgat gcagtcattt atggaggata cattgacttc atacccatgg
    71281 gttccgatta tttatatcct gttggctatg gccgttcatc gatatgatga accagaagtt
    71341 gcggaggaat tctatgttat ggaagaggca tatgacgata tgacttatga tgatacatct
    71401 tatgaggaac aaccagatag cgctcattct tccaggatcc aacgctatca ttgataggca
    71461 caaaatacga gagaggctgt gacaaccgtc gcagcctttt ttggtttatt gcaattgtct
    71521 agcatcttct gtaaaataga aacgttagag aaaatcttgt atcatagaaa attaagaaag
    71581 aaataagaac gcagctcggt accaaaaata tggtaaaatg gcacttgact gtaattcact
    71641 gaaaatcgct tggaggaaca caaatgttta aagatttgta tttatttatg aaggacattt
    71701 atcagaacag aaaattattg ctacagtttt cgatcaatga cttcaaatca agatatgcag
    71761 gatcgttttt aggaatctta tgggcgttta tcaatccgct atttactgta ttgatttatt
    71821 ggctggtatt tggtgttgga ctgaaagcac aaatgatcga tgcaaaatac ccatttatcg
    71881 tatatttagt taccgggatg attccctggt tcttcttctc agatgcattt gcatcaacta
    71941 cggttgtttt tcgggaatat acttatttag taaagaaagt cgtattcaat attcgtatct
    72001 tgcccacgac gaaaatccta tccaatctgt acacccattt attcttcatt ctgattggca
    72061 tagctgtcgc gcttataaat ggtatatatc cttcagcaat gtctttacag ctgatttatt
    72121 atttattttg catgtgtgct ttcttgacag gattgacttg gctgacggca tcgatccaac
    72181 catttttacc tgatatcatg caattaatta cgatcgtgct gcagttgatc atgtggacat
    72241 taccgatatt atggagccct aatcagtttg attcaggtct tgtaagcata ttgaaattaa
    72301 atccgctgta ctatgttgtt caaggttatc gtgagtcatt tttaagtgaa gcttggttct
    72361 gggagcatgg aacatatact ttgtatttct gggttttcac gttagtaatg ttcgtaatcg
    72421 gctctgcagt gttccgtaga ttgaaaccac atttttcaga tgtgctgtaa ggagaatagc
    72481 tatgacagaa tatgcaatta gactaaaaga tatcacaaaa tcttataata tgtacgcaaa
    72541 accttcggat cgatttcgtg aagccctcaa tccttttaag aaatcctatc atgatgtatt
    72601 ttatgcgttg aaaaacgtga atgtagaaat aaaaaaaggt gagatgatcg gtttcgtggg
    72661 agaaaacgga tcgggaaaat ctacaatgtt gaaaatcatt acgggagtac tgacaccaac
    72721 atccggcacg atggaaatcg aaggaaaaat ctcagctttg ctagaactag gatcaggatt
    72781 caatcctgag tattctggct atgaaaatat ctatttaaat ggaatggttc taggattttc
    72841 aagagaagaa gtcgatgaaa tggtcgatga tatcattgaa tttgctgaca tcggagacca
    72901 tatttatcaa cctgtaaaaa cttattcaag cgggatgttc gttcgtctag cttttgctgt
    72961 agcaatcaat gtgaatcccg atattttgat tgtggatgaa gcattggcag taggcgatct
    73021 tgaatttcaa ctaaaatgta tggaaaaatt tacagaaatc aagaactcgg gaaagacgat
    73081 tttattcgtt tctcatgata tcagttcgat tcgtcgtttt tgtgatcgtt cctattggtt
    73141 gaaaaacgga gaagtcgtcg aatatggcga tacgatggaa gtaacgacga attatgaaaa
    73201 ctttttaaag aaaaaatcag ttaaaacagt ggatcggaat aaaaaccaag tagaacggtt
    73261 cgccgctcca gatatcgtcg acgtgacgaa agcggaattg ttggataaag acaaaaatcc
    73321 ggtggatatg ctggaacaag gagaaaaact atacgttaaa gtaacttatg aagtaaaaga
    73381 tgatacaatc aaaaatccgg ttttaggaat tgcgctacga acagtcgaca atttttatgt
    73441 atgcggactt aatactctac tagatggtat caagattcct tggaaaaaag gagagaatat
    73501 cttttatctg gagtatgaaa agttaggttt gttagctggt gaatattatt ttgacgttgc
    73561 ggtctttgaa gaaaatgcaa cggttccttt ggtatataag acaaagtaca tgaacttgtt
    73621 tgtcagcggt tcttatatcg gagaaggcat cgtggtctta gaccataaat gggaagaagg
    73681 gactcatagc aatgaaatat gattttgaaa tggacctaga tgaacaaagc agtgtgggaa
    73741 aaattgccgc acagatcaaa ccaggaagta aagttttaga gtttggtccc ggaaacggcc
    73801 gattaacgaa acatttaatc ggagcaaaac aatgtgaagt gagcattgtt gagttagata
    73861 aggaattgtt cgattttgtc agcgaatttg ctcaagatgg attttatggt gatatcgaaa
    73921 gttttgagtg ggcaaactat tatgctggac agacatttga ttacgtcttg tttgcggatg
    73981 ttttagaaca tttggtagat cctggaaaaa cattgaagaa agtcagagaa tttttgaatg
    74041 aagaaggaga gatcctgatt acattcccta acttggcgca taattctgtc atgatcgatt
    74101 tgttcaataa ccaattgccg tgggcttctt atggtctcct agatgaaacc cataattctt
    74161 tttatactca tgatggcttc caaaaagttt ttgaaaaagc gggattattc attaatattg
    74221 aagattattt gtacttagct gtaggtgata cagaattaaa atcaacttat gaagaattgc
    74281 cggaagctgt acgctatgat ttcaaaatgc gaccatttgg tgaagtctac caatactttt
    74341 tctcattgat gaaacatcca gtagcacaaa gttccattgc agagccacaa aattctaatt
    74401 atgtaaaagt gttagaagta acccagcaaa cgaaacaaga tgaaacaatc caacaaatac
    74461 cattcaataa tttcacaggg gaaaatgaga cactaagttt ccccgtatca gaaacaacag
    74521 aaagaatggt gtttcgcttc gcgcaacaac ctagctttat cgaattcagc gcagaagctg
    74581 ccggagaaaa actaacattt atcgattcga atgctgtagt caaaacagta aatgattgtt
    74641 atttgtttga tgggaaagaa ttaccagagt tcgttctaac ggatatttct gggaaagaag
    74701 tgactatcca ttgtcactat cgctttatcg gggaattgac accaacaatg aaagaattgt
    74761 tggaaacgat tcgtcccatg gctgaagtca caaagcagct ttctgagaaa aatgacgaat
    74821 tagaaagaga aaatcatcat cttcttgagg aaaatacaag actagaccat acgttaaaaa
    74881 caaccacaaa tcgctattgc acattgttgg aaagtgatga atggacaata aaacatagac
    74941 taggacgacg taagaaagaa acttcgaaaa aaatccaaga aaaagaactt tctatatgta
    75001 ttgacgagaa aatctgggat gcagaaacaa aaatattaaa aatcatcgga tggggaatcg
    75061 ctaattcgga tcgccagccc ttgtcctata agttatcagc tgaccaatcg ccatttttcg
    75121 aagcaattcc tgtttcacga gaagaagtca atcaagcaga acagctcgca aaaggaacag
    75181 aagcgggatt tgagttacga atcctttgcg agcaagaacg ttcattctta gtggaagcag
    75241 tagctcaaaa tggccaatca tggatcattg aaatgtaaat aatgattaac ttataaagat
    75301 aaggagtaaa cgaatcgtgc aaaaaaaaga aattgccgta tttatcgatc aaatcactcg
    75361 tgaacgggcc actggcgatt tgcttattgt gggctgggca attgatgaag tgaccaaaga
    75421 aatccctacg ataaaggtag aaaaagaaaa tgtgattgct gaagcaacac atgtcgtaag
    75481 attggatatc aatcatttat ataatcttga tgttaagacc caaagcggtt tcaaggtacg
    75541 tttatcaggg aaaatgagag gaaaagccat cttagacttc caaacagcga gacatcaaaa
    75601 tggcatagct gtgaaattaa acggtaaata cccttatgat gacggcattg aatcttcatg
    75661 ggaaagaaaa aaaagattac tgaaaaaagg gataaattat gcaaggactc atggcgtaaa
    75721 aaaagcgatc cgtcgggtca aattggaatt gaagccagga tcgatcgact atgcagagtg
    75781 gatcagtcgt catgagaaac cagatttgaa agagcaaagg aaagaagcac aaggatttgc
    75841 gtaccgtcca ttgatttcca tacttatgcc tgtctataac gttgaaatca aatggctcga
    75901 aaaatgcatt gattcggtac tggatcaaac gtatgatcat tgggaactat gtatcagtga
    75961 tgatgcttct actgatccag ctatccgaaa gtgtctggaa tcctatcaag caaaagatga
    76021 tagaatcaaa gtcgttttcc gaaaagaaaa tggacacatc agtctggcaa ctaattctgc
    76081 attggaaata gcagaaggag aatttatagc actcttagat aatgatgatg aattaccgcc
    76141 atttgcatta tatgaagtgg caaaagtgct aaacgtacat ccagaactgg atgtgatcta
    76201 cagtgacgaa gataaaatcg atgcagatgg caatcgcttt gatccgcatt tcaaagcaga
    76261 ctggtcgcct gatacattga tgggaaataa ttatatctct cacttaggcg tatatcgaac
    76321 aagcattgtt aaagaacttg gcggtttccg taaaggctat gaaggttctc aagattatga
    76381 tttggtcctt cgtgtgacag aacaaatccc tgcagatcat atttaccaca ttgaccgagt
    76441 cttgtatcat tggcggacga tcccaggatc aactgcaagt aatggcgaag ccaaaagtta
    76501 tatctatgat tccggagtga aagcattgac agatgccctg tctagaagaa acatcaaagg
    76561 aagcgtacgt cctggcagaa tttctggatt ttatgagatt gcttatgacg tcttgcaaga
    76621 ggatttggtc agtgtgatca ttccaacgaa gaatggctat gaagatctaa aaacttgtgt
    76681 ggattcgatc atcgaaaaaa cgtcttattc aaattatgaa atcattattg cggataacgg
    76741 aagtacagat ccaaaaatgc aagaattatt tgcagaatac aagcatcagc tgaaagaccg
    76801 ctttatcgta gaattgattg acattccatt caattattct cgaattaaca atttagcagc
    76861 agaaaaagca aacggcaaat actttttatt cttgaataac gatacagaag tgattgagcc
    76921 agattggatg acggtgatgg tttcttatgc acagtttgat cgaatcggct gtgtaggagc
    76981 aaaactgttt tatccagatg atacaacgca gcatgcagga gtattattag gaatcggtgg
    77041 tgttgcaggg catgcattga ataactatga tcgaacacat tgtggttatt tcggccgatt
    77101 ggtcattgac gtcaattact tagcagtcac tgcagcttgt atgatggtca aggcagctga
    77161 cttcaatgct gttaacgggt ttgatgaaac attagaagta gcattcaacg atgttgactt
    77221 gtgcttgaaa gtttatgaac tgggtcgtta caatgtctat gcacatcaag cagaattgta
    77281 ccatttcgaa tctaaatcaa gaggttatga agatactcca gaaaaacaaa gacgttttgc
    77341 tggtgaaatc aaaaaaatgc aagataaatg gccagcatat attgcgcatg atccatttta
    77401 caatgataat ttaacaaaag acggaatcgg cgacttttcg ttgagaccag attaaactat
    77461 aataaaaagc tgttatgttg tgattcgctc gcacataacg gctttttata gttttttgtc
    77521 aaaaaaaggc agaaggtgcc gactcaaaaa aataagtcga ggttgggaca gaagtgttta
    77581 actccgagaa ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcggc
    77641 ttatttaaga agaagttgct tctgctccca ccgtttattc gtttttaaag aatgagacaa
    77701 aagtgtttct tacttttgtc ccacgctctt attcatgctc agagcgccaa tagatacaaa
    77761 atcatagcca aagtttcacg aaccctagct gtcaaagaat cgatatttta ttttaatata
    77821 ggctatttta aaataaatgg tttaaggtat tcctctacaa aagccactct atcaattatc
    77881 atgggtttaa aataagaagt gatggagata accagattgt tcttagcgtc aatataaaga
    77941 acatttccac tattaccaat tgctgaatat atttcgttct cagaatctaa tacccaccat
    78001 aaatagccat atctcatatt ttgtaagtct tctaaagcac tggttctagg tttgaacatc
    78061 tcgtttatcc acatgggtgg tacgatttgt tttcctttat acatcccttt atttaggcat
    78121 aatacaccaa tttttgccag atcacttgcc gataaacaca aaccatatcc tgccgtcccg
    78181 atatttagtg gatcacaaaa ccagacattg gttttaggag acttatccat tgtaaactgc
    78241 ttatgttctt cagctgtttc agcataataa ttgacatggt ttggtatccc tataggatca
    78301 aatagatact tattggcaaa atcaacagtt gttagcttac ttgtctgata caacaagcca
    78361 gttaatatgt gtaaacagac agtttgatag ttgaattcgc cggttatacc ttttcttcct
    78421 cccaataaat ctagtgatgt ttttgtccaa tcttcacttg aacagacttt tgtccatgga
    78481 tcgcctttac atttgtaggg tgctttcatt gttagcaagt gcttgattgt aatagcgtaa
    78541 atagttttct ccccgcgttt cactttatac tctggaaaat aatctaatac tttatcatcg
    78601 atacttttga ttaatccttg ctctaaagca atgccaatca gcaaagatac aatacttttc
    78661 gttgctgaca tgatatgaca agtatcgtct tttttataac cattccattc atctgtataa
    78721 acttctaccc catccttata tgcgacaatt tgacatatat ttggttgtcg aaaaccaata
    78781 aaatcatgca actcttgttt attcataaga tattacctca ctttcttcta taagcataat
    78841 gtcattaaaa atcgatttca attttttcga ttcttcacgt aatacaggta ttcttatgga
    78901 ctagacagcg ctttgggaag atggattctc tgaaaaatat aaaggttcac tttatgagtg
    78961 gataaaaaaa gcagcaaata cttcgacttc tttaatttac caacattagt gaaaatcgat
    79021 tcatctggag atttgtaatt tagagtcctt gtcttgatta gaggtgtata aagcttttta
    79081 ttagacattt ttaaattcca ttacaatttg cttataaact aggtttttaa aggtgactat
    79141 ggtaagataa tagagatatt attttgtgat taggagtgta tatatgaata aaaatggaga
    79201 atggagtgct gcacgacgga tattcattat attaatggat gttattgtat acaatgcagc
    79261 aatatatagt agtttcttac tgaagtttcg tggagagatc ccattacgaa atttagaaac
    79321 tttccaacac tcagcaatta ttatttcagt gatttttatt gcgttgaaca ttttgttggg
    79381 tgcatatgtt ttttataatc gaatgatcag tgacatcgtg tttgtcacag tcatcggtca
    79441 ggtattgatg acactaggga tcatggtagt gacttttgcg ggccgctggt ttgcttttcc
    79501 acgtcttgtt atcttacttt catttgttct cggtacgctt ttcttaagta tctatcgtat
    79561 tctcgtatat aaactttatt tacgcgtaag tcgagataaa aaggtcgtca ttattgggtt
    79621 agaaaaggat gtcgcaccag caatccaaaa ttttggttca aagaaaaaca acaaacataa
    79681 agtcgaagca gtcattcttg ataactatta tgcaaacatc aaaaatatga ttaaagacat
    79741 cgatattgtc tatcttgctt ctcatatcga agaaactgaa aaaatcaaaa tctatcaatt
    79801 agttactaaa aatgaaaaaa aattgttttt gaatacaaca tttgaaaact tgacattgat
    79861 caatccaaat attatgaatt tcgaagatga aagtattatt gaagcatctg gatttagaat
    79921 ccaacctgaa tatgaactat tcaaacgttt gtttgatatc atcgtttcac ttgttttatt
    79981 agttattgct tcaccattta tgttattcac agcaatttta gtcaaagtga catcaccggg
    80041 accaatcatc tataaacaag tgcggatcac aaaaaatcaa aaggaatttt caatctataa
    80101 attccgctcg atgaccgcca cagccgaagc aaaatctgga ccagttttag ctaagagcaa
    80161 tgatgcacga gtaacgcctg taggtaaatt tattcgagct gtccgctttg atgaattacc
    80221 acaaatcttc aatgtgctga aaggcgatat gtcgatcgta ggaccacgtc ctgaacgttc
    80281 tttcttcgtc gatcagttca atgcagaaaa cccttattac tacttacggc ataatgttcg
    80341 tgctggtatc actgggtatg cacaagtcta tggaaaatat gtctctgatt acaacagtaa
    80401 attacgtttt gatttacttt atatcaaaaa atattcattg atgcttgatt taaagatctt
    80461 gctgcaaacc atcaagatcc tatttgataa aatgtcctct caaggacttg aagaagacga
    80521 aaatgtgatc tcattggcag aaattgcttt tccgaatgaa aaaatctttc gctagttggg
    80581 aggcgtaaaa atgaacaatc cgaaattcag cataatcgta ccagtataca atgcagaagc
    80641 aactattggt cgaacgattg atattctaaa agaattggat tatgaagagt acgaagtcgt
    80701 tttagtaaat gatggatcaa cagatcaaac acaggaaatc attcaagaac tgattgaaaa
    80761 tgatgaacgt tttgaattga ttactacgac caatcaaggg cccggattag caagaaacga
    80821 aggaataaga cagtcaaaag gagaatatct cttattcttc gatgcagatg acacgccagt
    80881 aaaaacgatc ttgtcagatt atgatcattt gctagaaaag agtccaaaag cggatcttgt
    80941 tgttagttcg tttgtttttc gtacaatgga cgagggaaga atcgtttccg aaaaagaaaa
    81001 cttagttaca gaatgtcact atctaactca cgaagagttt ataaaagaca tgtatcagtt
    81061 aatgaatgaa cagttgatgt atgttgtatg gaacaaatgc tatcgtagcg atattctgaa
    81121 aaataaccaa attctattta aaacttataa tagttgtgag gatcgaatat ttaacttaca
    81181 ttattatgaa tactgtcatc aagtgatcat gaacccaaaa gtagaatata tttatgaatt
    81241 tgaaggtggg aaggggatca ctaatcaata ccgacctaac aagttcgaaa catttaaaga
    81301 attctattca ttagcaaata ctgtaacaga cgatattaat aaagacggta tggcggcgct
    81361 tcttttaaaa gggacaactt cagttatttt ttctatttat agtacctctg caagaacttc
    81421 aaaagagaag aaagacgaag caaagcagat attgagtgat ccagtgatcc gagaagccaa
    81481 gcaaattgct aagacggatt cttcagcaaa aaaaataaca aagttgcttt acaatatgcc
    81541 agctccacta tttttatctg ctgtaaaagt tggaagcttc gttgaagtga aaatgccagg
    81601 gttaatggct gctttgaagc gagtatatta gttaatggag gaaaatataa tgaaaagaat
    81661 tttgcatttt cagggacgaa tgggtttagg tggagcagag tctttcatga tgaatttata
    81721 tcgtaaaatt gatcgtacaa actatcaatt tgattttttg atttatgaag attatgcaga
    81781 tgttcaagac tatcattcag agattgaaag attaggaggc cgtatttttg ttgtacctaa
    81841 tcctaagaa
//
LOCUS       DACGDM010000005        76068 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.005, whole genome shotgun sequence.
ACCESSION   DACGDM010000005 DACGDM010000000
VERSION     DACGDM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.005"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            48..1106
                     /locus_tag="IXR05_000377"
     CDS             48..1106
                     /locus_tag="IXR05_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAQ4258925.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1125..2144
                     /locus_tag="IXR05_000378"
     CDS             1125..2144
                     /locus_tag="IXR05_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAQ4258926.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2246..2962)
                     /locus_tag="IXR05_000379"
     CDS             complement(2246..2962)
                     /locus_tag="IXR05_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4258927.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     QPLTCYELTKNGRKKLTDYC"
     gene            complement(2931..3716)
                     /locus_tag="IXR05_000380"
     CDS             complement(2931..3716)
                     /locus_tag="IXR05_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4258928.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDGGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3707..4456)
                     /locus_tag="IXR05_000381"
     CDS             complement(3707..4456)
                     /locus_tag="IXR05_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAQ4258929.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4754..5278
                     /locus_tag="IXR05_000382"
     CDS             4754..5278
                     /locus_tag="IXR05_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258930.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5294..6793
                     /locus_tag="IXR05_000383"
     CDS             5294..6793
                     /locus_tag="IXR05_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAQ4258931.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6881..7483)
                     /locus_tag="IXR05_000384"
     CDS             complement(6881..7483)
                     /locus_tag="IXR05_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4258932.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7587..8543
                     /locus_tag="IXR05_000385"
     CDS             7587..8543
                     /locus_tag="IXR05_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAQ4258933.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8848..9804)
                     /locus_tag="IXR05_000386"
     CDS             complement(8848..9804)
                     /locus_tag="IXR05_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4258934.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            9978..10538
                     /locus_tag="IXR05_000387"
     CDS             9978..10538
                     /locus_tag="IXR05_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258935.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10531..11355
                     /locus_tag="IXR05_000388"
     CDS             10531..11355
                     /locus_tag="IXR05_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAQ4258936.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11365..11982
                     /locus_tag="IXR05_000389"
     CDS             11365..11982
                     /locus_tag="IXR05_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAQ4258937.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12000..12683
                     /locus_tag="IXR05_000390"
     CDS             12000..12683
                     /locus_tag="IXR05_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAQ4258938.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13366..14601
                     /locus_tag="IXR05_000391"
                     /pseudo
     CDS             13366..14601
                     /locus_tag="IXR05_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
     gene            14609..15496
                     /locus_tag="IXR05_000392"
     CDS             14609..15496
                     /locus_tag="IXR05_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4258939.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15513..16349
                     /locus_tag="IXR05_000393"
     CDS             15513..16349
                     /locus_tag="IXR05_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4258940.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16352..16975
                     /locus_tag="IXR05_000394"
     CDS             16352..16975
                     /locus_tag="IXR05_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258941.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQPDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            16972..18264
                     /locus_tag="IXR05_000395"
     CDS             16972..18264
                     /locus_tag="IXR05_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4258942.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18623..18720
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18836..19417
                     /locus_tag="IXR05_000396"
     CDS             18836..19417
                     /locus_tag="IXR05_000396"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAQ4258943.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19420..20727
                     /locus_tag="IXR05_000397"
     CDS             19420..20727
                     /locus_tag="IXR05_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAQ4258944.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21020..21508
                     /gene="purE"
                     /locus_tag="IXR05_000398"
     CDS             21020..21508
                     /gene="purE"
                     /locus_tag="IXR05_000398"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAQ4258945.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21492..22625
                     /gene="purK"
                     /locus_tag="IXR05_000399"
     CDS             21492..22625
                     /gene="purK"
                     /locus_tag="IXR05_000399"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAQ4258946.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22638..23933
                     /gene="purB"
                     /locus_tag="IXR05_000400"
     CDS             22638..23933
                     /gene="purB"
                     /locus_tag="IXR05_000400"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAQ4258947.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24113..24490)
                     /locus_tag="IXR05_000401"
     CDS             complement(24113..24490)
                     /locus_tag="IXR05_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258948.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            24746..25474
                     /locus_tag="IXR05_000402"
     CDS             24746..25474
                     /locus_tag="IXR05_000402"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAQ4258949.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25474..25728
                     /gene="purS"
                     /locus_tag="IXR05_000403"
     CDS             25474..25728
                     /gene="purS"
                     /locus_tag="IXR05_000403"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAQ4258950.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            25730..26401
                     /gene="purQ"
                     /locus_tag="IXR05_000404"
     CDS             25730..26401
                     /gene="purQ"
                     /locus_tag="IXR05_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAQ4258951.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26402..28624
                     /gene="purL"
                     /locus_tag="IXR05_000405"
     CDS             26402..28624
                     /gene="purL"
                     /locus_tag="IXR05_000405"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAQ4258952.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28609..30048
                     /locus_tag="IXR05_000406"
     CDS             28609..30048
                     /locus_tag="IXR05_000406"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAQ4258953.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30080..31123
                     /locus_tag="IXR05_000407"
     CDS             30080..31123
                     /locus_tag="IXR05_000407"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAQ4258954.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            31120..31698
                     /gene="purN"
                     /locus_tag="IXR05_000408"
     CDS             31120..31698
                     /gene="purN"
                     /locus_tag="IXR05_000408"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAQ4258955.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31695..33230
                     /gene="purH"
                     /locus_tag="IXR05_000409"
     CDS             31695..33230
                     /gene="purH"
                     /locus_tag="IXR05_000409"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAQ4258956.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33246..34520
                     /gene="purD"
                     /locus_tag="IXR05_000410"
     CDS             33246..34520
                     /gene="purD"
                     /locus_tag="IXR05_000410"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAQ4258957.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34642..35556
                     /locus_tag="IXR05_000411"
     CDS             34642..35556
                     /locus_tag="IXR05_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAQ4258958.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35689..37254)
                     /locus_tag="IXR05_000412"
     CDS             complement(35689..37254)
                     /locus_tag="IXR05_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4258959.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37247..38698)
                     /locus_tag="IXR05_000413"
     CDS             complement(37247..38698)
                     /locus_tag="IXR05_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4258960.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITA
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(38712..39728)
                     /locus_tag="IXR05_000414"
     CDS             complement(38712..39728)
                     /locus_tag="IXR05_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4258961.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            39948..41036
                     /locus_tag="IXR05_000415"
     CDS             39948..41036
                     /locus_tag="IXR05_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4258962.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41090..42616
                     /locus_tag="IXR05_000416"
     CDS             41090..42616
                     /locus_tag="IXR05_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAQ4258963.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42618..43823
                     /locus_tag="IXR05_000417"
     CDS             42618..43823
                     /locus_tag="IXR05_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4258964.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44080..45057
                     /gene="guaC"
                     /locus_tag="IXR05_000418"
     CDS             44080..45057
                     /gene="guaC"
                     /locus_tag="IXR05_000418"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAQ4258965.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45321..46745
                     /locus_tag="IXR05_000419"
     CDS             45321..46745
                     /locus_tag="IXR05_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4258966.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47206..48315
                     /gene="pdhA"
                     /locus_tag="IXR05_000420"
     CDS             47206..48315
                     /gene="pdhA"
                     /locus_tag="IXR05_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAQ4258967.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48318..49295
                     /locus_tag="IXR05_000421"
     CDS             48318..49295
                     /locus_tag="IXR05_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAQ4258968.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49320..50615
                     /locus_tag="IXR05_000422"
     CDS             49320..50615
                     /locus_tag="IXR05_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HAQ4258969.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            50623..52029
                     /gene="lpdA"
                     /locus_tag="IXR05_000423"
     CDS             50623..52029
                     /gene="lpdA"
                     /locus_tag="IXR05_000423"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAQ4258970.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            52191..52466
                     /locus_tag="IXR05_000424"
     CDS             52191..52466
                     /locus_tag="IXR05_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAQ4258971.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            52472..53239
                     /locus_tag="IXR05_000425"
     CDS             52472..53239
                     /locus_tag="IXR05_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAQ4258972.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            53407..55236
                     /gene="typA"
                     /locus_tag="IXR05_000426"
     CDS             53407..55236
                     /gene="typA"
                     /locus_tag="IXR05_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAQ4258973.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            55497..57269
                     /gene="recQ"
                     /locus_tag="IXR05_000427"
     CDS             55497..57269
                     /gene="recQ"
                     /locus_tag="IXR05_000427"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAQ4258974.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            57383..57685
                     /locus_tag="IXR05_000428"
     CDS             57383..57685
                     /locus_tag="IXR05_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAQ4258975.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            57688..58851
                     /locus_tag="IXR05_000429"
     CDS             57688..58851
                     /locus_tag="IXR05_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4258976.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            58877..62305
                     /locus_tag="IXR05_000430"
     CDS             58877..62305
                     /locus_tag="IXR05_000430"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAQ4258977.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            62326..63450
                     /locus_tag="IXR05_000431"
     CDS             62326..63450
                     /locus_tag="IXR05_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258978.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            63440..63877
                     /locus_tag="IXR05_000432"
     CDS             63440..63877
                     /locus_tag="IXR05_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4258979.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            63861..64199
                     /locus_tag="IXR05_000433"
     CDS             63861..64199
                     /locus_tag="IXR05_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAQ4258980.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            64318..64878
                     /gene="rsmD"
                     /locus_tag="IXR05_000434"
     CDS             64318..64878
                     /gene="rsmD"
                     /locus_tag="IXR05_000434"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAQ4258981.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            64875..65366
                     /gene="coaD"
                     /locus_tag="IXR05_000435"
     CDS             64875..65366
                     /gene="coaD"
                     /locus_tag="IXR05_000435"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAQ4258982.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            65356..66399
                     /locus_tag="IXR05_000436"
     CDS             65356..66399
                     /locus_tag="IXR05_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4258983.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            66558..67286
                     /locus_tag="IXR05_000437"
     CDS             66558..67286
                     /locus_tag="IXR05_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAQ4258984.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            67402..67647
                     /locus_tag="IXR05_000438"
     CDS             67402..67647
                     /locus_tag="IXR05_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4258985.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            67644..67862
                     /locus_tag="IXR05_000439"
     CDS             67644..67862
                     /locus_tag="IXR05_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAQ4258986.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            67998..68537
                     /locus_tag="IXR05_000440"
     CDS             67998..68537
                     /locus_tag="IXR05_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAQ4258987.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            68530..70803
                     /locus_tag="IXR05_000441"
     CDS             68530..70803
                     /locus_tag="IXR05_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAQ4258988.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            70841..71887
                     /gene="holA"
                     /locus_tag="IXR05_000442"
     CDS             70841..71887
                     /gene="holA"
                     /locus_tag="IXR05_000442"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAQ4258989.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(71976..72230)
                     /locus_tag="IXR05_000443"
     CDS             complement(71976..72230)
                     /locus_tag="IXR05_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAQ4258990.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(72630..72899)
                     /locus_tag="IXR05_000444"
     CDS             complement(72630..72899)
                     /locus_tag="IXR05_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258991.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(73369..73824)
                     /locus_tag="IXR05_000445"
     CDS             complement(73369..73824)
                     /locus_tag="IXR05_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAQ4258992.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(73962..75890)
                     /locus_tag="IXR05_000446"
     CDS             complement(73962..75890)
                     /locus_tag="IXR05_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4258993.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
BASE COUNT        24639 a        13131 c        16505 g        21793 t
ORIGIN      
        1 aaagcttttt ttattgtgaa taaatgaaca taattaggag gagaaagatg aacttatttg
       61 acatttttcg atcgactttg acagatatgt cgattgtcag tgcaatcact tcaacagttt
      121 ttattatatt attagggttt gtttgtagaa aaaaggggat tttttctgaa tctgttggaa
      181 aaattctatc gaaagtcgtc ttaacagtgg ctttgccagc actggcattt cgagctttca
      241 tgcaagatat caatacagaa ttactgatgc aaggaatcaa tgtcttgatt tggggattag
      301 ttatttatat tattcttatt ctagtttcaa aacctttttt cttaagctat aaaggggata
      361 agcaaacaac gttgcgtgtc ctgacgatct ttggttctac gacctttttc ggaacgccta
      421 tcgtcagtgc gatttatggt cctgtcggcg tgatgtattc ctcaattttc aatattggct
      481 accgaatctt tttgtattct tatggataca taaaaatgag tggcttgaag atggaagcta
      541 aaaatatcaa agcgatgttc gtcaatccaa tcattatcgc tacttttgcc ggccttttca
      601 tttggctgtt ccaagggtat ctgccacaag tgtcagttac aggtgcagaa ggagagataa
      661 gccaagtagc gtttttgcga attgaccaga ctgcaccgtg gctatttcag ccgatggatt
      721 atttagctgg tttaagttca ccattggcgt ggctagcaat cggcgcaaca ttaggtgaag
      781 taagcttcaa aaaagctgca tctgaaaaaa cttcatggta ttacagtcta gtcaaagtgg
      841 tatttgtacc tgcattgaat atcgtgattc tagcagtttt gacggcaacg aatattctac
      901 cagtcaattt tgaagcactg gcaacaatcg ttatcatgat ggctacacca gctgcaacag
      961 tggcagcagc ctatgctatc agttttgata gggaggcact tttagcctcc aatgcatcct
     1021 tactgtcaac tatttttgct gtggtactga cacctgtatg gatcgttgta ttacaaatga
     1081 ttcatggcat aggtttattt tcataagaaa tggaggaaga aagtatgaga atcgcatgtt
     1141 acggtgttcg tccgaacgag atagattttt ttgaaaaatt gaatatttac cattatgatc
     1201 tcagtcttta tgaagaactg ttgacacatg acaatatcgt gtcagcaaag gaccatgatg
     1261 ctgtattgtt gaggggaaat tgtatagcag atgagaccaa tcttgcaaaa atgcaggaat
     1321 atgggattcg ttatgttttt acacggactg tgggagtcaa tcatatcgat ctacaagcgg
     1381 cagctgattt tggtatgaca gtagcccgtg taccatcgta ttcgccaaat gcgatagcag
     1441 agttatcttt gacttttgcc atgatgcttt tgagaaatac tgcgtatacg acgatccgaa
     1501 catctttcaa agattttcga gtggatgagc aaatgtttag tcgtgaaatc agaaattgca
     1561 cagtagggat cataggaaca ggcaggatag ggttgacgga agctgttttg tttaagggac
     1621 taggagccaa agtgatcggc tacgatattc atcagacaga agctgctaaa aaagtattga
     1681 cgttccactc gcttgaagag ttattagcca aaagcgatat tgtcagtatt catgtacctc
     1741 atatcccagg tgaaaacgat caaatgatca atgaaggatt tttagctcaa atgaaaaaag
     1801 gtagcatctt gattaataca gcccgtggag agcttcaaga taatgaagct attttaagag
     1861 ctttgaaaag caatcattta gctggttttg caaccgatgt ttttgcaaat gaaacagagg
     1921 tttttttccg atccttcaag ccatgggaga cgattccaga ccctgctatc cagcaattag
     1981 tagaaatgta ccctagagtt cttgtaaccc cgcatgtagg ttcaaataca gatgaggcat
     2041 tatcaaatat gatttcgaca agtttcgaga actttcgtga aataatagaa actggaaaaa
     2101 cgaaaaatga ggtatctctt cctaaagccc gtcaattaag ataagaaaac atggatattc
     2161 gtcaataaaa tgtttaaaaa tagtccaagt aaacagttgt tacttctgta tacttggact
     2221 attttgtatg ggataattcg atgactcaac agtaatctgt gagctttttc cgcccattct
     2281 ttgtcaattc ataacaggtt agcggctggc cgatttccaa atatttgatt ctttcgttca
     2341 atatatcttg ttctactaaa aaattcaaat atttcttgac ggatatacgt gacagtgagc
     2401 ttttttgagc cagttctttt gttgaaaaaa tagtatcttc ttttagaata aatgcactta
     2461 ttttttttaa agtcagtttt gacagacctt taggcaaatc gatgaatgat ggtatttcgt
     2521 gaatgggagt ggtgtggttg aatacttgat cgatcaattt ctgatcggct ttttcagtcg
     2581 tttggattgt ctgagagaaa gcaagatact tttcgatcgc cagctgaaaa cgttgcaaag
     2641 tgaacggttt gatcaaataa tctaaggcac cgtagcggat cacattcttt atggtttcga
     2701 tatcatctgc agcagtgatc aaaatcactg ggatatcatt tccttgctgt ctaagccaag
     2761 ataaaaaatg gataccactt tcgccaggca tgtatacatc aagcagcagc agatctgcgt
     2821 ttttttgtct gaaatatttt tttccttctt ctacatttct gaaactttcg attacgttca
     2881 tattagggat gctttccaca aaagtacgat tcaattctgc aaccattgga tcatcttcga
     2941 ttatcaggac atttgtcatc attttgatct tccttttttg gtaattctag atagacgatt
     3001 gtaccgccat ttgtttgttt ggaaaattct aaaaatccac cgtggcgttt gacgattgaa
     3061 tggatgagat tcaatccaaa cccacgattg attcccttcg tcgaaaaacc tagcgtaaat
     3121 attttttctg agatttcttc tgatatcccg acaccgccat cgcagacggt cacgatgaat
     3181 acttcagctt ctgtgtcata gtttaaatga atccggacct gtccgtttct ttcatgtttt
     3241 tgtagcacgg cttcttttgc attatcaagt aagttcccta acacttgcaa aagtgaatgg
     3301 atggagtcat ccatctccat tttagggata aaagaatcgc tttctaacag catttcaaca
     3361 gattgttctt tggcttcgtt tattttgcct aataaaaaac cggcaattgc aggtactttg
     3421 atcagacttg agacttggcc aatctctttt ttataatttt gatttagctg ctggataaaa
     3481 tgggtgactt cttcatactt cttcaaatca atcaaaccag aaatgacatg aagtttattc
     3541 atgaattcat gggtttgagc tctcatggag tttatatatt gtttcgtccc cccaagctcc
     3601 tccattaatt tcattacttc tgatcgattt cgtaaagttg cgactgctcc taaaaaacgg
     3661 tcattgctaa aaagaggtgt aacgctagaa atagtttcta tcccatttaa atacatggat
     3721 tgagtccgaa cggtcgtttg atgctcaatc gtctctttaa acaaaacgtc atatagatta
     3781 tcactgattt ttttcctact tcgaaatcca atagctgctc tgtttggtag aaaatgtttt
     3841 ttgcaggtgt attgatcaag aggatagttt tatcagaaga gatggctaag attccttcat
     3901 ctacttcatt ttcgataatc gttttttcac ttaactgttc tgctatttct tgtggttcaa
     3961 gtccaagcag tacttttttc attttttggg caagaaaaac ggcgcctatg atgcctacgc
     4021 taagtccaat aatcaatgaa aaaacaatca ttttttgtcc atctttgact tgattgtcaa
     4081 tcgtgttgtt tgttaagcca acacaaactg caccaataat ctcttgatca taataaatag
     4141 ggacgaaata gcggaagccg aaccctaaca ttccttcttt ttcagagaaa aattcttgtc
     4201 ctccaatcac ttttttcaca tcttcatgac ttgagaaagg aagaccgatg taacttgggt
     4261 ctgcgtgaga atatcgaatg ccttcagggt ccatgacaac gataaaatct aaattcgatg
     4321 caatcatgat ttcatttgtt attccttgaa tcgcatgtgt cgggtcacca gtctgcagct
     4381 ttttttggat gagtttatca ttggcaacga ttttagcaat gctagagatt ttatctgaca
     4441 cactagatcg gttcatcgaa agaataaaat tcctgatcaa tatggcagaa acaatcaaag
     4501 aaacgaatgt ggagaaacaa acgacaagga tgatcgtgtt ctggagcttt aatggttttt
     4561 tcttaaaaaa aggaaacata ggctacctcg aaagaattta ttgtgaaaat tttaacatga
     4621 aaacaaaaat ttaacaaatt gtcaacgata aacacaacct tcctataaaa aacaccactg
     4681 agtcggtaaa agaagctata cagaattttc aaacattggt atgatagacg tagaaatgga
     4741 aggaggcgtg tatatgatag ggggaatcgc acttgagacg atttattggt atacattgct
     4801 gatttgtgca ggattggcag tcctattgat tatttttgga gatgtattcg attttgatgg
     4861 cccgcttgat ccgatgctta ttatcccttg gttaactttc acaagcttat ttggttttct
     4921 aggtgagcgt ttaacagatc aatcatcttt atttttattt attgctagtg gaggcatatc
     4981 gatagtgttg gtatttttgc ttaatttcta tatattgatg ccgatgaaac atgccgaatc
     5041 aacgatgtcg tcttctgaaa aaactctgga aggacaagta gctgttgtga tcacaccgat
     5101 ccctgtacga ggtatgggag aaattcagtt gaaaagtgtt accggttcca ttagtcgtcc
     5161 agcttgtttt tacagccccc aagaacagac agctgagcgg ggaacgaaag tattgatcat
     5221 tgagatcaag gaaagaatct gttatgtcat gccttatgaa agcatgataa aagcttaaag
     5281 gagcgtgtgt taaatggaaa taccagttgt ttttatcgcg atcgcaatcg cagctttgat
     5341 tttactgatg ttgctgatcg tctttgtagc gaagtaccag acagcaaaac cggatgaagc
     5401 gttgatcatc agtggaagtt atttaggaag caaaaatgtg cacattgatg aaagcaataa
     5461 caaaatcaaa attgtgcgtg gaggtggcgc attcgtcttg ccagtttttc aacgttcgaa
     5521 tcggatcagt ctattatcga gtaaattgga cgtctccacc cctgaagtgt ataccgaaca
     5581 aggcgtaccg gtgatgtgtg atggtacttc gatcatcaaa atcggttcat ctgtagaaga
     5641 gattgctaca gcagcagaac agtttttagg caagacaaga gaagaactgg aaaatgaagc
     5701 aagagaagta ttagaaggac acttgcgctc gattcttggt tctatgactg tagaagaaat
     5761 ctatcaaaat cgcgataagt tcagtcaaag cgtacaagaa gtcgcttctg tagaccttgc
     5821 aaaaatgggg ttgatcatcg tttctttcac tatcaaagag gtcagagaca aaaacggtta
     5881 tcttgactct ttagggaaac caagaatcgc ccaagtcaaa agagatgcag atatagcaga
     5941 agcggaagct ctaaaagaaa cgcgtatcaa aaaagctcaa gcagaaaaag aatcacaagc
     6001 agctgaatta cagcgacaaa cagagatcgc agaatcatta aaagaaaaag aactgaaatt
     6061 agcaacctac aaacaagaac aagatgttgc taaagcaaaa gcagaccaag cctacaattt
     6121 agaaagtgcc cgagcacaac aacaagtaat cgaacaggaa atgcagatta aaatcgtaga
     6181 acgccaaaaa caaatcgaac tggaagaaaa agaaatcaca cgtcgtgaaa agcaatatga
     6241 ttcggaagtg aagaaaaaag cagatgccga tcggtacgct aaagaacaag aagcacaagc
     6301 tcaaaaagtc aaagaagtga ctgaagccga agcagaacga ttccgtgtgg aagcactggc
     6361 agaagcggaa gccaataaga cacgtttagc tggacaagca gaagccgaag cagcactagc
     6421 aaaaggaaaa gcagaagccg aagcaaaaca aaagatcgcc aatgccttca aggaatatgg
     6481 cgaagcagct gtcttgagta tggttatcga tatgctaccg caattgatgc gcgaagcagc
     6541 acagccgcta ggaaatatcg aaaaaatctc tgttgtcgat acaggaagca gttcaggaga
     6601 aaccagtgga gcgaaccgag tgacaaatta tgccacaaat ttgctttctt ctactcaaga
     6661 aacactaaaa gcgacaacag gacttgactt gaaggaaatc gtagagaatt tgtcgacacg
     6721 tgggactact agccaagtaa atatgtatga agcgccaaaa gaggcagaac aaaactcgat
     6781 gaaggaagaa taaagtagta cacttcaccg ttcaatcaaa aatggaggaa gactttttaa
     6841 agttcttctc tccatttttt tattttattg caaaagaaaa ttagtcctcg ctatttttct
     6901 tttgtttttg gatcttagct tctatctctt gtaaatttgt tcttagcaat cgttctttct
     6961 tttggagttc gaccaaatct tctgatagtt cttccttctt ttctgtttca ggaggacgaa
     7021 gaaagaaatt gataccgatt gcaatgaatg tccctataaa agtatctagt acacgttgga
     7081 tagcatacaa agcggattcg ccttgaggga tgctcaacgc aatcagcaac aacgtagcta
     7141 ttgcggaaat gataccggaa ttattgttaa taccatctga cacgacgatc acaataataa
     7201 ctagaatagg aagcaagatc aattctacca aaaaatcatt gtgaaaatag cttttgacaa
     7261 aaaaataaat gatagctaat gtaccaccta atgtattgcc gatgatccta gactttccaa
     7321 aagaaacggt tgtagtcaag tcctgacgca aagaaaaaac agcagataat gcagcaatca
     7381 tcgggattcc tcgttgagtc aaatgaaaaa acaagataca taaaaaaaca gctaaggcac
     7441 ttttgatcgt acgcatacct agtcgaaaac ggccaaattg catagagatt ctcctttttg
     7501 gtctttttac tatcatacct aaacttttgt ctgatagcta gtttttcatt attcaagtat
     7561 aattaaaata aaaaaggggg aagtaaatgc gtataggaat gcgaacagtc aaaacagtga
     7621 tcagtgtctt cttttcgatg gtcacagcgg gtagcttatc gctgttgtat tggccagctg
     7681 cagggatcat tgcattatta agtgtaggaa ataccaagcg ctctacattg cgtacgggca
     7741 tgaatcgaat cgcagccttt atattagcta cggcaacagc actgttcagt ttttttgctg
     7801 ttgggtatac tatttttggc ttcagtcttt ttttattcct gttcatcccg cttgcctctc
     7861 gcttcaaatt aaccgaaggg atagtagtaa attcggtttt ggtcactcat tatttagtgg
     7921 aggaaaacat gtcttggcag ctgatcggca atgaagcggg attaatggcg attggattag
     7981 tatttgcttt gcttgcaaat gtttacatgc cagatcgtac gaagcagctg aaggaaaacc
     8041 aaatacagat cgaaaaagaa tttcgaaata ttttgagaca aatggcagaa tttcttttat
     8101 cagaaaataa agaagatgtg cagatcaaat gcgaacattt actgacattc attcgcgaaa
     8161 gccaagaaga tgccagagaa catcaagaaa actactggct cagacagccg ctatactacg
     8221 aaacttactt ctctatgaga agagcacagg ccaatgtgat taaagacatg ctggaaaatc
     8281 tagagagaat ccagcaacca gcttattatg gaaaacatat ctatggttta ttgatttata
     8341 ctgcagaaac attttcagag tcaaatgatg gcagacaaat tttaacacgt attgaagaag
     8401 tttatgtatt gtatcggcaa atgcctctgc cgactagtcg ccctgaattc gaggatcgag
     8461 cagaattgtt ccagtttttg cagtctttta aaagttttat tgaaatcaag gcagaattct
     8521 cccaacaaaa aatccaaaaa tagaggttgt gaattcagct aatattcagg tcaaaaagct
     8581 gatttcacaa cctcttcttt aaacggtgtt ctcctgtcaa ctcctcggtc acaagtcaca
     8641 atattcaaca aacatgagaa gctgtttttt gaaattgctc cttgtgactc ggagctgaac
     8701 ggtaggctca caacctcttt cttaaacggt gttcaaaagc tttcctctgc ggtaataagt
     8761 ccagccaaac gaaaaatagg aggagctatt tttgtttggc tgttcttatt acttgatgca
     8821 gaacagcttt ttcacaacct tttaaaatta catatttttc catagaactt gcatttgatc
     8881 caagatttcg atgacatctt ttgtcaagaa gagagagcga ttgggcaagt caccttcaat
     8941 catgtgtacc atattcttta tttcgtaatt cattgcttca gatgtattcc cgctttcgat
     9001 gaattccttt gtaccatctg taaataagat ctccgcacga tcagcacgcg ggtaatcagc
     9061 aatcgtcaca taaccgttct caaaggcaac gataccgact tttggcattt ttgcctgaaa
     9121 agtcaagctg acagcagcaa gttcattttc tttgttacgc aagatagtga cggattgttc
     9181 gtccacgcct gtttcaaaag gaaccattgt agaggcaact acttcaggtt gagagctcaa
     9241 aaagaaacga gcgaaagata cagcatacgt accgatatcc aacagagctc ctccagctaa
     9301 ttctggattg aagaaccggt ttttagggtc tggttctttg taactgccga aaggtgcttg
     9361 gatcattttt aaagccccca gttttcctgt atccattatt gagcgtaact gctgataaag
     9421 tggcatgttg aagattgtca tcgcttctgc taagatcaaa ttcttttctt ctgctaagcg
     9481 catagcgtca gccagttctt ttttattcat cgtgatggct ttttcacata gaacgtgttt
     9541 gcctgcttcc aatgctgcca agatatggtc gatatgctgt ctatttggta cagcaatgta
     9601 cacgatgtcg atttcagcat cgtctaacat ttcttgatag cttccgtaag cttttggaat
     9661 attgtaacgg tgagcgaagt tttccgcttt ttctgaagtt ctggaagcaa ctgctgttag
     9721 ttcgctcgtc tcttgattga agctttcggc aaactcatgt gcgatggtac caagaccaac
     9781 gattccccat tgatattttt tcatctgaaa acgctccttc atagttggat tgagtttctt
     9841 gtctgtctat tattataaca aaaatcacga agaataaaga ggagaggact tgaaacatta
     9901 aaaaaaatga aagcagcgat ttaagaggtg ctttttgatc aaaacttaag tagaatagtt
     9961 aaaaggaggg gataaacgtg catcaagtat atattgatct tattatgagt gtattattag
    10021 aacagtttga aactgaaaaa aattttttag atgaatactt gctgatcagt ccagaacaat
    10081 ggcaaaaatg gaaagatggc gagaaaaatc tgccatctga agcgatgcag aaagtaaaaa
    10141 atcttttcac tgattatgaa tggatgctaa cgcaaaagat tttgcgtcaa acgattattt
    10201 ttcccgaaaa acgaaacgtt gccgttgcag agtacaagca aatcaaaaca cgcatcgcgc
    10261 aaaaatggct tagcagcaaa gcagcaaaag tcgagctgat ccctttgaaa aataatcagc
    10321 aggctggtag ataccttgac ttgaaagtaa gtattcaata tgatgaatgg ggctatgatg
    10381 atattttgaa ttttcgtctg ccagcagatg ttcaaaaaca gatcgaagga gaaaaaatcg
    10441 aacttctcga ttgggtgaat gaaaatctgg aagaaactta cgttcatgag gcgaatgggg
    10501 aacgtgaaga acaacgaaag gatttttcaa gtgaataaat ttttaggatt tggagcagtt
    10561 gtgattatga tcgcagcaat gggctatgtt atttttagcg atgatgattc gcatgttcaa
    10621 gccggcaatc aagcagtcga acgaacaagc accaaaacaa ctgctagtaa agaaaagaac
    10681 agtcaaacaa ccagcagcaa ggtaaaggac aaagaaacaa aagatcgtac gtccaaacaa
    10741 ttgccagatg ttaaaacaga cgattggaag ctagttttgg ttggtccaga tcacaaatta
    10801 gaaaaagaaa ttgatgagtc tactcaattg gcatcattaa gtaacggata cttgatcgac
    10861 aaacgcattg ctccagaata tgaagcattt gccaaggctg ctgaagcagc tggatttcca
    10921 ttagtgatgg tctcagctta ccggtctgta tcatcccaac aacaagtttt cgaacaaaat
    10981 gtccaagatg tgatgagtcg tcaaggtgta tcagaagagg aggcgacaaa gattactaaa
    11041 gaaacgatta cggagccagg atacagcgaa caccacacag gtctggcagt cgatgtcgtc
    11101 gatcaaaact ggtacaacag ttatccttct actgtattgg atgcaagtta cggagatcag
    11161 cctggagcta aatggatcgc agataatgct gcgcagtatg gatttatcgt tcgttatcca
    11221 aaaggacacg aagatataac taagatcaca tatgaacctt ggcacttacg ttatgtcggt
    11281 aaagaaaacg ctgagtatat caccaaacac caattgacgc tagaagaata tctgaatgaa
    11341 ttaaatgaaa agtaggaatt gatcatggcg aaaaaaaagt ggaaaaagca aaagcgcaag
    11401 aatatccgtt ggccagcagt ggttgccggt gtagcagtga tactcttagc ctttgttttt
    11461 tccttgaaga atctgtcttc tccttttact gataatcagc aagaaaatga agcgcaatcc
    11521 catcagcaat ttattgaacg gcttgttccg catgcccaag aactacaaga tggttatgga
    11581 gtgcttccta gtatcatttt aggacaagct atattagaat caaattgggg aaaaagtacc
    11641 ttggctagca aatacaataa tcttttcggg atcaaggctt atggggatca gaagaaagta
    11701 agcctggaaa caaaggaatt tgttaacgaa gaatggataa ctatccaagg agacttcaaa
    11761 gtgtatgatt catgggaaca gtccatggat gaccatacac aactgttcgt ccaaggagta
    11821 gattggaatc ctgcgctgta tgaaaaagtg attacggcca ccaactatca ggaagccgca
    11881 caagcattgc aagatgcagg ttatgcgaca gaccccggtt atgcgcaaaa aatcatccag
    11941 gtcatcgaga cgtatcaatt gaatcagtat gaccggagat agcaaaggag aagtggctga
    12001 tggcagaaca atttacgcca gaaatcatga cggaattgag aaaagatatc gtaagagtac
    12061 cggaaatcat tttagaagca agcgggatca agatatttgg aaaattgatc cgttcgatca
    12121 tctttactac ggatattgcg atcatacgta atacaaatgc gaatgcagta attgctgtgt
    12181 atccttttac acctcatcca gcgattacta aaagcattat tgaggcagct gacattccag
    12241 ttttctccgg tgtaggtggt ggtttgacac aaggtgctcg ttcttcctac atgagcatgt
    12301 tcgcagaagc gcaaggttcg ttaggggtcg ttttgaacgg tcctacgcct ttagagacag
    12361 taaaagaagt ttgtcgagta gttgatattc cagttatcag tacggtaacg tcgaaatata
    12421 cagaaataga tgaaaagtta gcagctggta tttcgattat caatatcagt gcaggtaaag
    12481 aaactgcaga agcagtacgc cattttcgta aaaaatatcc tgaacttcct atcattgcga
    12541 caggtggtcc aacggaagaa agtattgctg agaccattca agcaggagca aatgccatca
    12601 catatacgcc accaagtagc ggagagcttt ttagtcgtaa aatggaaaaa tatcgggaaa
    12661 ctgagaaaaa gaatcatgaa taacaggtga gaatcaaaag acgaggaaga gcagatagtg
    12721 gctcttcctc gtcttttgta ctccagtact atttgttcag aattcaaaaa aaagagaaat
    12781 ttttttgttt ttttacctgt aatgtacata agaagagtta aaaccttttg ttattattag
    12841 cattctaaca aaaaaatgtc ttgatttatt gaagcgcttt ctatagaatg aaaaacgaat
    12901 aaaaactaaa aaaggcaccc gacaatttag tagcagctaa attgtcgggg cttgaaaagt
    12961 cagcgggaac tgaccaatca agttgccata gtcaatgctt gtgcatcgac gtgtatattg
    13021 tacctaattt catacagaat tactagttat ttttctgttt tttagggaag agcgcacacg
    13081 aagaagcatg cttatttagc tatgtcaagg atattgggca gttgtctgat atcctttttt
    13141 ctttgcgtaa ttatcctccc atcattgaag caagaagtgt ttttagcgat gaaagaagaa
    13201 tcagcactat ctaatttttc ttgaaagtat tgagttgttc atcctaggca gaacgataag
    13261 gcaagtcttg gtttttattc cccttgaaaa agatcgttta ataaatatgt tctgtataaa
    13321 aatacagtat attgaaaaat aacaatggaa gtagaggtgc agagaatgaa gaaaagaatg
    13381 agaatcatct tagctttaag tgttatgtta ttcttcttga cggcttgtgg gcaagaagat
    13441 gacaaaaaaa tcacgctgaa catggcttgg tggggttcgc aagtccgaca cgatgcaaca
    13501 gtaaaagtaa tcgagcttta tgaagaaaaa aatccccatg tgacgatcga ttatgaattt
    13561 tatgattatg aaggatatta cacaaaatta ggtacactag cagcatcaga tgatatctgg
    13621 gacattttcc aactgaacaa tcaatttcct caatacatca atcagattga accattagat
    13681 gaatatgtgg agcaagggat aattgatatt tctaatgcag atgaatccta tttagcaacg
    13741 acgacttacg acgggcaatt agttggactg tctaacgggg tgaattcgtt tgcgattgct
    13801 tacaataaaa atatatttga acaattaaat atccctgaac cagcttcaaa ttggacatgg
    13861 gatgaatttg aacaaatcag ctatcaaatc actgaagaat taggaatcta tgctatttca
    13921 agattcgaag attttatagc tggctgtatt attcaaatac cacaagttga gaaaggattg
    13981 aatttttata atcgggaaga tctatctaac agcttgggat ttgaaaatcc agactatcta
    14041 acagattttt tccagctgcg taaaaatctg gtagacaaag gggcccatcc agaaccaggt
    14101 ggtggagctg caagtacgac ggatctgtct tttcaggcgg ttagggatag agaagcggca
    14161 atggtgtttc tatcaagtaa ccagttgaca gaaatattgt caggggctcc tgaagatatg
    14221 gagattcagt tgattaatcc acctcgcaga aaagcagatg gagaatctgg tatcccttta
    14281 cgttcttcgc aaatgctgag tatggcaaaa agctcagccc ataaagaaga agctgctaag
    14341 tttattgatt tctttcaaaa cagtgaagaa gccaatgaaa ttttaaaagg agaacgtggt
    14401 gtaccaatca tgtcgaatat tcgagaacag ctcgctcgtg cagatgatgc aactttgcaa
    14461 gcgacatttg attatttaga aatgatttcc gatatggaca acggcgaagt gaatgtcttt
    14521 gatagtgctt tgaatccgga aattcaagac caatacaatc ttttagttga aaaagtcatt
    14581 tatgaagaag taacagcaga aggaaggcat gaaaaaagaa aaactaaaac ggttcttgga
    14641 tcaagacaat gtggtcggtt acgtatttgc ttctccattc atcctaggat ttctattgat
    14701 aacagtgata ccgatgatct tgtcacttta ttattcgttc accgattatc gtttgggaaa
    14761 tccagtctca tggatcggct tggataatta tataaagatg ctgagtgatg cccgtttttt
    14821 gaactccatc cgagtcactt ttctctatgt atttgcatct gtacctgtga aactgatctt
    14881 tggtctattg attgcttatc ttttaacgag gaatatcaaa ggaacgactt tctttcgttc
    14941 tttgtattat gtgcctagtt tgatcggtgg cagtatttct atcgctctag tttggcggga
    15001 gttgttttct aaaaacgggt tagtgaatat tttcctggaa cgattaggcg cacctgcgct
    15061 ttcctggttt agcgatcaaa aactggtcat gatccctctt gttttgatgt ctgcttggca
    15121 attcggttcg gcaatgatca tctttgctgc aggtatcaaa gagatcccag gctcgtatta
    15181 tgaagcggca gagatcgatg gagcgaacaa atggcagacg ttttacaaga tcacgttacc
    15241 tcttctttcg ccgatcattt tgtataactt ggttatgcag acaatcgcgg cgtttatgac
    15301 ttttacgcag gcatttatca ttacccaagg tggtccgaat gatgccacga acttttatgc
    15361 tctttatgtg tataaccaag ctttttcttt taattctatg gggtatgcta gtgctatttc
    15421 gtggatcatg ctgttgatta tgggagctgt cacctttctg attttcaaat catcaaaaaa
    15481 atgggtcgtt gtgtgaatga gaggaggaag aaatgaataa tacagtaacg aaatggtttc
    15541 aatacggttt tattttgcta ttaggtctag tcatgattta tccggtctta tggatgatcg
    15601 caggttcttt taaaacggat caagagatta tgagtggttc gctgaatttg attccagaga
    15661 cttttcaatg ggaaaattac gcaaaaggat gggcggggtt tgctggaatt tcatttttta
    15721 ctttctttag gaattcgttt gtcatctctg cagtttcgac gatagggaca gttctgagct
    15781 cgacttgtat tgcttacgca ttatcgagaa tcgatttcaa aggaaaaaga ttctggttcg
    15841 tcgtcatgtt agtaacgatg atgattcctg cacaagtgat tttgattccg cagtttatta
    15901 tttacaatcg gctgaatttg gttgggacgt atgtgccgct gattttacca catttttttg
    15961 gacaagcatt tttcatttac cagatcatgc aattcatggt cagcatcccc aaagagttag
    16021 atgaatcagc gattattgac ggatgcagca agtatagtgt ctttaccaaa attatttttc
    16081 ctttgctgaa accttcgatc atcacgacga tcatcatcca gttttattgg aaatgggacg
    16141 acttcatggg accattgatt tatttaaaca agccgagatc ttacacggta tcgattgcca
    16201 tcaaattatt tgcagacgct ggatctagta cgacttacgc gagtatgttt gcgatgtcta
    16261 cgttgtcgct gctaccggtt tttctgattt tcttattctt caataaatat cttgtccagg
    16321 ggatcagtac aagcggtctg aagggctgaa tatgaaaaag ccaatagaag agatgtttct
    16381 ttacaagctc aactactatg tctgtcggat ttttttaacc agtcttatca gtaatgctct
    16441 tttcgcttta gttctaggat gtttgttcac tttaggatta gtgctgtctg ctcgtgttgt
    16501 ctatctgatt tattttttga tgatgtatcc ttcttattat ctatctgtcc attacttggc
    16561 agaaaaaaag gtatgttgga ggaaagggaa aatcaaacgg atgtgtttca tcattacgtt
    16621 gtttcagctg tttgtcatta tttttgcagt tgattggtat ttattagtgg gaaagattgg
    16681 agcttggtat ctgattcctt ttctattgtg tctgttgctt tttgtatccc atagtttttt
    16741 tagtacgcta attgatatct gcaaagaaga taaagcagat agtcttgttt atttgatcaa
    16801 aaggaatatc tggctgttgt caaaaaacgt caaggggttt ctgtggtatt tatgcctttt
    16861 gtatggactg ttctggtgta tacagcctga ttttttactc actgcattac tgtatccagg
    16921 gctgccattt gtcacagtat tttgcttaaa agaaaaggag aatgacttta aatgaagaaa
    16981 aaatatgtac aagtcggact tggtgggaga gcgcgttttt tttatgaggc aattgcctct
    17041 acgtatcatc aaacttgtga actagtcggt ttttgtgatg tatctcaaac aaggatggat
    17101 tatgcaaatc ggatacttgt gaacaagtat ggacagaaaa aagtaaagac atgtatgcca
    17161 tcacaatttg agcaactact ggatgacgta cggccggctg aagtcattat tacgtcagta
    17221 gatcgaacgc atcatgatta tatcattcgt gcaatgaaaa aaggatatga tgttatttgc
    17281 gaaaaacctc tgactatcga tgaggaaaaa gctcaagaaa taataacggt ccaaaaacag
    17341 acgggaagaa gcctgcgagt cacttttaat tatcgttatg caccgtatca cacgaagata
    17401 aaggaactga tagaaagtga tgtgattggt gatgtgtttt ctatccactt cgaatggctg
    17461 ttaaatacgc aacacggggc agattatttc agaagatggc atcgaaataa gcacaatagc
    17521 ggcgggcttc ttgttcataa atctacccat cattttgatc tagtgaattt ttggttgaac
    17581 agccgtcccc aaaaggtatt tgcattcggt ggattaaact tttatgggat gcataatgcg
    17641 gagaaacgcg gagtagaaat attttacagt cgatgctatg gaagcgaact agctaaagct
    17701 gatccatttg ctatagacct gtcagccaat gaggaattgc gagaaatgta tttagaagca
    17761 gaaaaagaca gtggatatat tcgtgaccgc agtgtatttt ccgatgatat ctctattgaa
    17821 gatacactag gcgtaacggt caaatatgaa actggtgcga ttttgacgta ttcgctaaac
    17881 gcgtatatgc cgtgggaagg attcaatgtt tctttcaatg gcagcaaagg acggatcgaa
    17941 atgaaagtga tcgaaaagtc ttacatcaat gcaggtggag ataaaaagga tgaaggagca
    18001 gccgttcttc agtccatcca tgtctatccg atgttcggtg agccatatga ggtaatcgtc
    18061 gaacaagaag cgggcggaca tggcggagga gatccgcgtt tattagatga tctatttggt
    18121 gaagaaaaag aagaagatcc gtggaatcgg gcagcaactc acgtagatgg tattttgtcg
    18181 attttgacag gaatcgcagc aaatcattct attgcttcag gaaaagcagt agtgattgac
    18241 gagcttgtca gcttaaaaga ataagaatag atttacggaa attacttccc gtagtttata
    18301 aaatcttgcc ttattgccga taggctgtct tttgaacact atttattcgg aaaaaggggc
    18361 tatgacatgc tttttgtcat gccttctttt tatgtgggct gcttttttag ataggagaaa
    18421 ataaaaataa ctatttaaac ccgaacaaaa aggaataatg cattaaaaat cattagattt
    18481 tacaaaaaaa taagtaaacc acgttgtcag tttcagaaag tagtgttaga ctgttttcaa
    18541 tatttgaaac aacatttttt attcaaatat ggcaaactgc cttcacgtgc aaaacagttg
    18601 caagaaaatg aatttacact attattagtt ttacatacct acttatatat cgtcataata
    18661 tggatgacag tttctagcca gtaccgtaaa tgctggacta taagtaaaag attggctatt
    18721 tcacccttct tttcttatga taaagtggag ggtgtttttc tttaacagaa acatagtagg
    18781 tttttgcaca aaagcggtta tttcggtatt aataaatgat aaaggagcaa ataaagtgaa
    18841 agaattagtt gaacgtattc aaaaagacgg acgtatatta ggcgagggcg tattaaaagt
    18901 cgacagcttc gtcactcacc aagtagaccc tgtattgatg gaacaaatgg gaaaacggtt
    18961 tgcagaagta tttaaagaac aaggaatcac gaaagttgtg accattgaag cttctgggat
    19021 cgcaccagct ttatttgctg caagagaatt agatgttcca atgatcttcg ctagaaaagc
    19081 aaaaagtttg acgatggatg aagaattatt gacagcttct gtttattctt ttacgaaaca
    19141 agtgacaagt acgatttcta tttctcgtaa atttttatct tcagaagaca aagtattgat
    19201 tatcgacgat ttcttggcaa acggacaagc ggcaaaagga ttgatcgaat tatgccagca
    19261 agctggagcg caagtagaag gaatcgggat cgtcatcgaa aagtctttcc aagatggacg
    19321 tcagttactt gaagaaatgg gattgagagt cgtttctctt gcgcgtattg cttccttgac
    19381 gaatggacaa gttgagtttc ttgaggagga cgcataatcg tggaaaaaga aacacaaaat
    19441 ggaaaagctg cggttttagg gctgcagcat ctgctagcga tgtatgcagg agcagtagcg
    19501 gtgcctcttt tgatcggtac aggactaggc tttaatcaag aacagatgac ttatttgatt
    19561 tcaattgata tctttatgtg tggattagcg acattattgc aattgacagt taaccgattt
    19621 ttcggaattg gcttgcctgt cgttttagga tgtgcgatcc aagcagtagc tccactgatc
    19681 ttgatcggaa ccaatgaagg agtaggagct atctacggat ctattatcgc ttctgggatc
    19741 tttgttgtgt tagtttctgg tgtcttttct aaaattaaaa aactattccc tcctatagta
    19801 acaggaacgg ttatcaccgt tattggtttg actttgattc ctgtagcaat cgagaaaatg
    19861 ggtggaggta atgcaacagc agctgatttt ggtgacaaaa caaatctgct acttgcattt
    19921 gtgacgattc tcctaattgt aggcgtgcaa atgctggcaa aagggttcat tcgttcaatc
    19981 gcggtattga ttggtttagt cggaggaagc atcttagctg ctttcatggg aatgattgat
    20041 ctgagcgcga ttggagatgc gccgttgttc catgttccac aaccctttta ttttggtaaa
    20101 ccaactttcg acgtatggtc gattttacta atgatcatca tttccatggt cagcatggta
    20161 gaatcaacag gtgtatattt tgcacttggt gacattactg ggaaaaatgt tggagaagaa
    20221 gaattgaaaa agggatatcg tgcagaagga cttgccgtta tcttaggcgg tattttcaat
    20281 acattccctt atactggctt ttctcaaaat gtcggattgg ttcaactttc gggaatcaaa
    20341 acaagaaaac ccatctattt ctctgcattc ttcttgattg ttttaggatt attccctaaa
    20401 atcggtgcgt tagcacaaat catccctgag ccggtacttg gtggaggaat gttagtcatg
    20461 ttcgggatgg tggcagtcca aggaatccgt atgctgttgg aagttgattt cagcaatgat
    20521 aaaaatctat tgattgttgc tgtttctgtt ggatttgggc tgggtttcaa tgttacgccg
    20581 acattattca gtcaaatgcc gcaaacattg caaatgttca ctggaaatgg catcgtaatg
    20641 agtagcatta cggctatcat attgaatttg atctttaatg gattgaaaaa agatgaagaa
    20701 atattggaag aagccttcaa gaagtaatag agcaaaagaa aggttgtgaa atcagcgttt
    20761 tgacctgatt gttagagaaa caaacggaaa aatagttcct cgtattttgc cgtttgtttg
    20821 agctaatacc gagggtcagc tgattgaaca ccgtttatcc ataaaaagga atgtgaccta
    20881 acttttgtca cattcctttt tttcatcttt aataaacacg aacaataaaa tgtttttctt
    20941 tgttaacatt cgaaatttct ttgacatcaa aaaaagtgat tgttaaaata tgaatgtaga
    21001 aaaactggga ggaaaaacaa tgacagcaaa aatctctgtg attatgggga gtacttcaga
    21061 ttgggaaaca atgaaagaag catgtcaaat attggatgaa ttcggtgtgt cttatgaaaa
    21121 aaaggtcgtt tctgctcatc gaaccccaga tttgatgttt gaatatgcac aaaacgctcg
    21181 aaaaaaagga atcaaaatca ttattgcagg agcaggggga gccgcgcatc tgccgggtat
    21241 ggtcgcatca aaaacaactt tgccggttat cggtgtaccg gtccaatcac gaacattaaa
    21301 tggtttggat tcgcttcttt cgattgtcca aatgcctgga ggagtacctg tagctactac
    21361 agcaatcgga aaagcgggag caattaatgc tggactactt gcgatacaga tgctttccat
    21421 gtatgattta gaattggagg ctaaattggc tgaaagacgt tcaatgttgg ctaaaactgt
    21481 tatagaaagt agtgatcaac ttggttaaac ctttgttgcc tggttcaacg atcgggatcg
    21541 tcggtggcgg tcaattaggt cgtatgatgg cgattagtgc aaaagaaatg ggctttaaag
    21601 taggtgtgct ggatcctgtg agcgattgtc cagccgcaca agttgcagat tggcacattg
    21661 aaagtgtcta tgatgacacc tttgcgctga aagagcttgc cagaagaaca gatgtcatta
    21721 cctatgaatt cgaaaacgtc agtgtagagg cgttaaatgc gattttaccc atgtcattta
    21781 ttcctcaagg gacagacttg cttgcgatta cgcaagaccg cctgttagaa aaatcttttt
    21841 tggaaacgaa taacatcgtg attgctcctt atgcaacgat cgtcagtccg acggatatcc
    21901 aagatgcgat tgacgggatc ggctatcctt gtgttttgaa aaccactcga ggcggctatg
    21961 atggcaaggg gcagtatgtt ttgaaaagtc gggcggatct agctcctgcc atggaccttt
    22021 taagagaagg aacctgtgtt ttagaagcat ggatcccgtt tgaaaaagag atttcgatca
    22081 tggtggcagg aaatggtcaa ggagatttca cgacttttcc ggtcgtggaa aacatccacc
    22141 acaacaatat tcttcatgaa acgattgctc cagccgcgat tgatcaggat gtgatcgagg
    22201 aggctgagcg tattgcccgt gtgattgcag aagcagtgag cctttcaggt gttttagggg
    22261 tagaaatgtt tttaacaaaa acaggcgggc tatatgtgaa tgaattagct cctcgtcctc
    22321 acaattctgg acattattct attgaagctt gttctatgag tcagttcgat gcccatattc
    22381 gaggtatttg tggttggcca ttaggagaaa aagtacgttt gataagcaat gcagtaatgg
    22441 tcaatgtttt gggagaacaa ctgctggaaa gctatcgctt gattgagaat aagccagact
    22501 ggcaattcca tttctatgga aaaaaacaag caaaaaaagg tcgcaagatg ggacatatca
    22561 ctatcttgac agaagacatc cagcaaacgc tggaagaaat caaacaaacg aatatttggg
    22621 attagaggag aaaaaacatg ttagaacgtt atacacgccc tgaaatgggg aatatctgga
    22681 cggaagagaa caaataccgt gcgtggctcg aagtcgagat tttagcagat gaagcttggg
    22741 cagaacttgg tgaaatcccg caagaagatg tgaaaaaaat tcgtgagcat gcatcatttg
    22801 atatcgatcg gatcttggaa atcgaaaaat taacacgcca tgatgtcgtt gcgtttacac
    22861 gagcggtttc tgaaacattg ggagaagaaa gaaaatgggt ccattatggt ctaacaagta
    22921 cggatgtcgt agatactgct tatggctatc tcatcaagca agcaaatgat attttacggg
    22981 aagacttgaa acgttttacg gaaatcattg gcgaaaaagc aaaagaacac aaatatacag
    23041 tgatgatggg tcggacacac ggtgtccatg ctgaaccaac tacttttgga ttgaaacttg
    23101 ccacatggta ttcagaaatg aaacggaaca tcgaacgatt tgaacatgcg gcaaaaggag
    23161 tagaagcagg aaaaatctca ggagcagtgg gaacgttcgc aaatatcccg ccatttattg
    23221 aagagtatgt atgtaaacaa ttggggatcc gtccacaaga aatctctact caagttctcc
    23281 ctcgggatct acatgctgaa tatttctcag cgatggcgct tattgctaca agtattgaac
    23341 gttttgcaac agagatacgc ggattgcaaa aatccgaaac acgtgaagta gaagaatttt
    23401 ttgcgaaagg tcaaaaaggt tcttctgcta tgccgcacaa aaggaatccg atcggttcag
    23461 aaaatatggc tggtctagcc agagtggtgc gcggacacat ggtcactgcc tatgaaaatg
    23521 tcacattatg gcatgaaaga gatatttctc attcttcagc agaacgaatc atcttgcctg
    23581 ataccacgat tttattgaat tacatgttaa atcgttttgg caatatcgtt aaaaatctaa
    23641 cggtctttcc tgaaaacatg aagcggaata tgtctgcaac atttggtttg atttatagcc
    23701 agcgcgttat gctgaaattg atcgataagg gaatgacaag agaagaagct tatgatcttg
    23761 ttcagccaaa aactgcgtac gcttgggaca accaagtgca gttccgcccg ctgttagaag
    23821 aagatccaac catcacatcg gtattatcta aagaagaaat agacgatgcc tttgattatc
    23881 atcatcattt gaaaaacgtt gacgtgatat tcaaacgagt aggtttggaa taaagaagag
    23941 tgagttgcaa aattcaatta aaatagaata gcaaaaataa ccaaaaaaga agcagatccg
    24001 ttagcggttc tgcttctttt agtttattat attttcttat caataatagg aacctgattt
    24061 taaaagcggc tacctcttta ccgtgcctct ttacatacaa aaaatagagg aattaagcgt
    24121 aaatggcttg gctattataa ctaaaatgct ggttatggag atgttgcagc aagttttcga
    24181 gaaaagcgta ttccatctct tgtccattga ataagatctg gatacgataa tgatttttga
    24241 aacgcttctg ttcatgaatc tgactgattg aaagttcgcc tttgtgttct gtctgataaa
    24301 gaaaagtcct tttacggcat tcagcacagc gcttggttgc tcggcggatt tttcggaatg
    24361 tataaaaact agtatcttta ttgcataaat aaacgtcttt gatcgacagc aaatcattat
    24421 atagacagga acgttcttca gctgttaatt ctgataaaaa aagctgacct tgttttattg
    24481 catcttccat cggcaagtgc ctcctcgaac ccattatcca aatttttagt taattctaat
    24541 ataccatcat taagtataaa tgtaaacgct tgttgatggt ataagatttt cgtttctgat
    24601 aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac atatttttgt tgatttataa
    24661 aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa aaacgatgta tttgctttta
    24721 atgtaaataa aaaggagaga cgtacatgga gaagaaagaa cttttgtatg aaggaaaagc
    24781 caaaaaaata tatcttactt ctgatgagaa cttgatttgg atagaatatt tagatcaagc
    24841 aactgcgttg aatggcgcga ggaaagacca gataagtgga aaaggagaat tgaataatca
    24901 aatcacaagt gcaattttcc gttatctgac tcaaagagga ataaaaaatc attttattga
    24961 acaattgtct aaaaccgaac aattagcaaa aaaagtacaa attatccctc tggaagtggt
    25021 tatccgaaat attgcagcag gaagtttctc aaaacgtcta ggtgttcccg aaggtaaaga
    25081 attcatcaaa ccaatcattg aattctacta taaggatgac cagttggatg atccatttat
    25141 caatgaagag catatctatt tcttacaact tgcaaaaccg gaagaaatca gtgagctgaa
    25201 agcccaagcg ttggctatta atgaaatttt gaccgaatta tttgctaagg tcggtttggt
    25261 tttagtagat ttcaagctag aatttggccg gtcgaatgga caaattttgc ttgcggatga
    25321 agtaacaccg gatacttgcc gattatggga tgaacgtacg aatgaacata tggacaaaga
    25381 cgtttaccgc agagatctag gtgatttgat cccagtctat caagaagtat ataaccgtct
    25441 atcggaacta actgaagaaa aggagcgagt atgatgtatt tcgtaaaagt atatgtaacc
    25501 tataaagatt cagtgttaga tcctcaaggg gaggcagtaa aaaaagcagt ccatcgtatg
    25561 ggatatgaaa caatcgaaga tatccgaata ggaaaatact ttgagataca acttgctgat
    25621 gcagaagaac caatcgatac agtgattgaa acgatttgtg acaagctgct tgcaaatgta
    25681 aatatggaaa cataccgata tgaaatcaaa aaaatggagg aagtataaca tgaaatttgc
    25741 ggtcatcgtt tttccaggtt caaattgtga cgcagatatg ttatgggcag ttcgcgagat
    25801 catgggcgct gatgccgaat ttgtacggca tgatgagtcc tctttagaag gatttgatgg
    25861 ggttttactg ccgggaggat tctcctatgg tgactatttg agatgcggtg cgattgctcg
    25921 gttttctaca atcatggaag aagtgattcg ttttgctgaa gaagggaaac cagtattcgg
    25981 tacatgcaat ggattccaga tattgacaga agcaggactt ttgccaggtg tactgagacg
    26041 aaatgagtct ttgcatttta tttgcaaaac tgtaccattg aaagtcaacc ccaagacggc
    26101 ctttacttca gagtatgaag ccgacgaaat aatctatctt ccagttgctc atggggaagg
    26161 aaattatttc tgtgacgaag aaacacttca agaactaaaa aaaaataatc agattgcctt
    26221 tacttataat gacaacatca acggcagcgt ggaaaacatt gcagggatta cgaacaaagc
    26281 agggaatgtg ttaggaatga tgcctcatcc agaacgtgca gtagaagact tgctaggatc
    26341 agaagatggg aaacggttct ttgcttccat tttaaaaaac ttcggaaagg tgaccgtata
    26401 gatgaaaaca ttgaaagaac cgacagctga agagatcaag aaaaaaagaa tctatgccga
    26461 atggggattg actgatgaag aatatcgaat gatcgaagaa gatatcttag gaagaatgcc
    26521 taattatacg gaaactggac tgttttctgt tatgtggagc gaacattgtt cctataaaaa
    26581 ttctaaaccg gttctacgca aatttcctac tagtggacct catgtgttgc aaggccctgg
    26641 agaaggcgca ggcatcgtcg acatcggtga tggactagca gttgtcttca aagcagaaag
    26701 tcacaatcat ccttcagccg tggagcctta tgaaggagct gcgacaggag ttggcggaat
    26761 catcagagat attttcagca tgggggctcg tccaattgcg ttgctagatt cattgaggtt
    26821 cggcgaatta gataatccaa gaacgaaata tttactagaa gaagtagttg caggtatcgg
    26881 cggatacggc aattgtatcg gcataccgac tgtaggcggc gaaattgcat ttgatccttg
    26941 ttatgaagga aacccattag tcaatgcaat gtgcgtaggt ttgattgaac acaaacatat
    27001 ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg tatgtaggtg caaaaacagg
    27061 tcgcgacggt atccacggag caacttttgc ctcagaagaa tttaatcaag aagaagaaca
    27121 gcaacgttct gctgtacaag taggcgatcc ttttatggaa aagctgctgc ttgaagcgtg
    27181 tttggaatta atcttgcatc attcggattc tctaataggt atacaggata tgggagcagc
    27241 aggacttgtt tcatctagtg cggaaatggc ttcaaaagct ggctcaggac ttatattgac
    27301 attagatgaa gtcccacaaa gagaaactgg gatgacacct tatgaaatga tgttatcgga
    27361 atcacaagaa cggatgttga tttgtgttaa atcaggagag gaagaaaaaa tccaagaact
    27421 atttcagaag tatgatctag atgcagtcac tatcggtaaa gtaacagacg acgggcaata
    27481 tcggctatat catcaaggag aagaagtagc aaatctgcca gtcgatgcat tagctgaaga
    27541 tgcaccagtt tatcataaag aaatgaaaga accagctcga atcgtagaat ttcagcagtt
    27601 agctccttat cagccagtta tcgaagaacc tggacaagta ttgcttgatc tgctgcagca
    27661 accgacgatt gcttcaaaac gttcaatcta cgaaacttat gattcacaag tacaaaccaa
    27721 tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg gttagaggga cgaataaagc
    27781 gttagctatg accacagact gcaacgcgcg ctatctgtat ttggatccaa aaatcggagg
    27841 acaaatagca gtggcagaag ctgctagaaa tattattgct agcggtggta agcccttggc
    27901 gatcaccgac tgcctgaact atggttctcc tgataaacca gaagtttttt gggaattatc
    27961 gacttcagct gacggaattg ctgctgcgtg tgaaacgtta ggaactcctg ttatttcagg
    28021 aaatgtctct ttatataatg aaacggatgg tcaagcaatc tatccaacac caatgattgg
    28081 tatggtcgga ttgattgagg atcataaaca tatcactact caggaattca aaaaatcagg
    28141 ggatctaatc tatatattag gtaagacgtt tgcagatttt gatggcagtg aattacaaaa
    28201 gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt gatctatcca ttgaaaagag
    28261 aaaccaagag ttagtattga cagccatcca aaacggattg attgaaagtg ctcatgactg
    28321 ttcagaaggt ggcttggcaa ttgcactggc agaatcagct ttcaaacatc agctagggat
    28381 atctgtacag tttgaattgt cctctgctca attatttgca gaaactcaat caagatttgt
    28441 gttgacagtc gcaccggaaa ataagacacg attcgaagaa atgatgggag atgctgctgt
    28501 tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt tcagcaactg acggtcagat
    28561 caaaatagaa actgcagtag caagaaagtg ctgggaggat gcaatcgtat gtcttatgaa
    28621 gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt ggggtcatcc agacgccgct
    28681 agtgtggcat acttcgggct ccatagtctt cagcatcgag gacaagaagg tgcaggtatc
    28741 gtgtccaatg atcgaggaaa gcttaagggg catcgagatt tggggctgct ttctgaggta
    28801 ttcaaagatc aaagaaaatt gcagcagtta acaggagaag ctgcaatcgg acatgtacgt
    28861 tatgcaacag caggcaatgg aagtgtggac aatattcagc cttttctatt caaatttcat
    28921 gatcagtcga tcggcttagc gcataatggt aacttgatca atgctcgttc ccttagaaaa
    28981 gagttagagg aaaatggggc gatcttccat tctaactccg atacggagat attgatgcat
    29041 ttgatccgac gaagtgaaga aacagatttt ttaaataaat taaaaagtgc tttgaatgaa
    29101 gtcaaaggtg gctttgccta tttattaatg acagaaacgg caatgattgc cgctttggac
    29161 ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa acggagcata cgtgattgcc
    29221 tcggaaactt gtgcattaga agttattggg gcacgtttta taagagatgt ccagcctggt
    29281 gagatagtga tcatcaatga cgaaggaatc cagattgatt gctttacgaa ggacacgcag
    29341 ctttctattt gttcgatgga atatatctat tttgccagac cagattcaaa catcgcaggg
    29401 atcaatgtgc atactgcacg gaaaaatatg ggacggaatt tagcgaaaga atcgccagta
    29461 aaagcagata tggtcgttgg cgtacctaat tcttctttgt cagccgcaag cggttatgcg
    29521 gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa atcaatacat tgcccgaaca
    29581 tttatccagc caacgcctga gctaagagag caaggtgttc gaatgaaatt atctgctgta
    29641 cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg attcaattgt tcggggtacg
    29701 acaagcagac ggatcgtcca tcttttgaaa gaagcagggg caaaagaagt ccatgtgagg
    29761 attgcttctc ctcctttgaa atatccatgt ttttacggga ttgatattca aacgcgtaaa
    29821 gaactcattg cggcaaatca cacgattgat gaaatcaaag aatgtatcgg tgcagattct
    29881 ttaggttttt taagtgaaga gggtctgatc gaatcgatcg gtctggaaaa agatgctccg
    29941 tattcaggat tgtgtatggc ttatttcaac ggagattatc cgacgccgtt atatgactat
    30001 gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt tcttttaaaa gcagaccaag
    30061 aagggagtat atgaattcaa tggcaaatgc atacgcaaaa gctggcgtag atgtcgaagc
    30121 tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa aaaacggaac gtttaggtat
    30181 gatgggcgct ataggaggat tcggcggttg ttttgattta tcggtctttc aattaaaaga
    30241 gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa ttagcagtgg caatcgaagc
    30301 agacaaacac gatacaatcg ggatcgactg cgtagcgatg tgtgtcaatg atatcttagc
    30361 acaaggcgca gagccgttat atttcttaga ctacttagca acggggaaaa atgatccgtt
    30421 acgtttggaa aatgtagtaa aaggtgtagc agatggatgt gttcaaggaa atatggcgct
    30481 gattggcgga gaaacagctg aaatgcctgg tatgtactca ggtaatgatt atgatctagc
    30541 cggatttgct gtagggatag ctgaaaaatc tcaattattg acaggagaaa cgatcaaccc
    30601 aggagatgtg ttgcttggaa tagcatctag cgggattcat tcaaatgggt actctcttgt
    30661 tcgcaaaatt ttctttgagc agcagcagtt ttctttatca tcaaaactgc cagaattgaa
    30721 aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc tatgtttctt ccttgcttcc
    30781 gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc actggtggag ggtttgtaga
    30841 aaatatcccg cgaatgttac cagaatctat ggctgcacaa atcaaacttg gctcatggcc
    30901 gattcttcca atattcggct gtttacaaaa atatggtgaa attcctgaga tggagatgta
    30961 tgaaatcttc aatatgggca tcggtatggt cctggcagtc gaagaatcga aagtaaaaga
    31021 aatagtacac gaaattgagc aagctggcga aaaagtttat gaaatcggga aagtgatcgc
    31081 caaagaaaaa catcgtgtgg tgtttatagg agaagaacga tgagaatcgc tgtttttgct
    31141 tctggaaacg gaagcaactt tcaagcgcta gccgattatc tatcgaaaaa aggattggaa
    31201 tcttcgattg actggttgtt ttgtgatcag cctgaagcat atgttttgaa acgtgcaact
    31261 gcgttgagtg taccggcaga ttgtttttca cctaaagaat ttgattcaaa aaaagagtat
    31321 gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg atttgatcgt attagctgga
    31381 tatatgcgaa tcattggacc ggtattgctg aaaaattatg ataaaagaat catcaatatc
    31441 catccgtctc ttttacctgc cttccctggt ttgcatggca tacgtgatgc ctttgaagct
    31501 ggagtaaaag aaacgggtgt cacaattcat tatatcgacc aaggtgtaga tactggacca
    31561 atcatccggc aggaaaaagt gagaattgaa caggaggaca cgttcgattc tttagaagaa
    31621 aaaatccata gagtagagca tcgaatctat ccagaagtga ttagtgaaat tattgaaaat
    31681 ggaggctatc tgaaatgaca agagcattga tcagtgtatc agataaaact gggattgtag
    31741 cattcgccca aggtttgatt gaacaaggag tagaaatcat ttcaacagga ggaacaaagc
    31801 atgcgttgga taaagctggg atcaaaacgc tttcgatcga agaagtgaca gggtttcctg
    31861 aaatgatgga tggccgtgtc aaaacacttc atcctaaaat ccatggtggt cttttaggaa
    31921 gacgcgatct ccctagccat atggaggcaa tggaaacgga aaatatccaa ccaatcgact
    31981 ttgtttgtgt caatttatat cctttcaaag aaacgattat gaaaccagat gtcgaaatag
    32041 cagaagctat tgaaaacatt gatatcggtg gtcctagtat gctccgtagt gcagcaaaaa
    32101 accatgaatt tgtcacctct gttgttgatc catctgacta tgaagaagta ctttcagaat
    32161 tacgtcagta tgggcatact tcactttctt tcagacaaaa actagcggca aaagtctttc
    32221 gtcatactgc ggcatatgat gcactgatcg ctcaatactt aacggattgg gtggaagaaa
    32281 aagaaccgga aaaattgaca cttacgtatg aacgaaaaca aacgcttcgt tacggtgaaa
    32341 atagccatca agccgctgcc ttttatcagt ccgctcttct ggaaaaatat tcgatcgcag
    32401 cagcaaaaca actccatggg aaagaacttt cttataataa tatccgagat gcagatgctg
    32461 cgctacggat catgaaggaa tatgacgagc caacggtagt cgccttgaaa cacatgaatc
    32521 cttgtggtat tgggacagca tctacgattt tagaagcgtg ggaagcagcg tatgaagcag
    32581 atcctgtttc aatctttggt gggatcatcg ttttgaatcg agaagtagat ctgccaacag
    32641 cagaacagat gcataagctg tttctagaaa tcatcattgc cccttcttat acacaagaag
    32701 ctttggaatt actgcaaaaa aagaaaaaca tccgattact gacagtagac tttgcgcagg
    32761 aagaaaatca aaatcgagaa gaaacggtct cagtcttagg tggacttctt gtacaagatc
    32821 aagatctggc aatagaaaat gaagaagagt ggaaagtcgt gacaaaacgt aagccgactc
    32881 cagcagaagc aaaagcatta gcgtttgctt ggagagctgt caaacatgtg aaatctaatg
    32941 cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg agccgggcag atgaatcgag
    33001 tcggttcagt aaaaattgcg attgaacaag cgcaagagaa aatggaaggt gcagttttag
    33061 ctagcgatgc ttattttcca atggatgatt cggttgaata tgcagccaaa catggtataa
    33121 aagcaatcat tcagccagga ggaagcatca aagaccaaga ttctattgat atggcgaata
    33181 aatacgatct agcaatggtc tttactgatg ttcggcattt tagacattag agaggagtcg
    33241 gataaatgaa cattttggtg atcggtgcag gtggtcgtga acatgcaata agtaaaaaac
    33301 ttttagccag tccgaaggtg gatacggtgt attgtgcgcc aggaaatccg gggatgacaa
    33361 aagatggtat caattgtgtc gctatcagtg agcgagatca ttcagcgtta atccattttg
    33421 ttaagaaaga ggctattgat tggagtatcg ttggtcctga agttcctttg ttaaatggga
    33481 tcgtcgatga ttttatggcg gaaggattga aaatcttcgg tccgacaaaa gcagcagctc
    33541 tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga tacttatcaa atcccgacag
    33601 ctaaatccag aagttttgaa tgttacgaaa aagcagcagc gtatatcaaa gaaaatggtg
    33661 cgccaatcgt agtgaaagcg gacggcttag cagctgggaa aggtgtagtc gtggctacca
    33721 cagtgaagga agcgctggat gcggcagaac aaatgttgaa ccagcatcga tttggggata
    33781 gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga agaattctcc cttttggcgt
    33841 ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca agatcataag cgggcatttg
    33901 ataacgataa agggccaaat acaggcggaa tgggtgctta ttcaccagta ccgcaaattt
    33961 caaaaaagat gattgaaaaa gctgtggaag aagttttaaa accagcggct ttgggaatga
    34021 aagaactagg acgctctttc acgggtgttt tatatgcggg tttgattgct acgaaggaag
    34081 gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc tgaaacgcaa gtcgttcttt
    34141 ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt attagagaat cgtacagtag
    34201 agttaaagtg gcagcaagaa ggatacaatg taggcgttgt ggttgcagct gccggttacc
    34261 ccgaagaata tgagacagga atggttctac cagattttct ggaagaagag ctttctgttt
    34321 actatgctgg agtttcctca aataacggca aactagttgg agcaggagga cgtctttatt
    34381 tagtagaagc atacggtgag acgatcaaag aagcacagaa aaaaatttac accgcgttaa
    34441 tggataaaac gacagatgga acattttatc gtacagatat tggagaaaaa gctgccaata
    34501 gcgaactgat cgtgaagtaa atcagctgct tccatttata aaaaatacaa caaacataat
    34561 cggaagcgcc gattttagtg aagccttttc ataaagagtg tggtacactt ttgttgtgta
    34621 tataaataag gaggagttca gatgaaaaaa attcaattag gtacttctga tcagaaagca
    34681 gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg aagatccagt aaaagtgatt
    34741 gagacagctt atgaaaacgg cattgatttt tttgaccatg cagatattta tggaaacggt
    34801 gaatgtgaag aaatctttgc agatgctcta gcaaaaacat caatcaaacg agaagatctt
    34861 tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt ttgatttttc taaaaaacat
    34921 atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa tggattatgt ggatgcttta
    34981 cttcttcatc gtccagatac attggtagaa ccagaggaag tagctgaagc gtttgatgaa
    35041 ttggaacggt caggaaaagt tcgttatttt ggcgtcagca atcaaaaacc aatgcaaatc
    35101 gaattgctga aaaaatatgt tcgtcaacca ttagtagcta atcagctgca atttggcttg
    35161 aaacatactg gaatgatcga tcaagggatt catgtcaata tgacagatga agcaagtatc
    35221 gatcatgacg gtagtgtact tgattattcc cgattgcatg atatgacgat ccaagcatgg
    35281 tcaccatacc agtatggatt ttttgaaggt gtatttatcg ggaacgaaaa attccctgaa
    35341 ttaaaccaaa cattagaaga actagcagct aaatatcaaa cgacaccaac tggcttggct
    35401 tctgcttgga ttttacgcca tccagccaat atgcaagtga tcgccggtac gatgaacgta
    35461 gggcgaatca aggaaatcgc tcaagcttca gaaattaata tgtctcggga agattggtac
    35521 gaattgtacc gtgctgctgg aaacatttta ccttaaagat tgtcataagc aggtcaaaag
    35581 ggctataaat taaaaagaca gaataacttg aaagctgttt tcagcttcga gatattctgt
    35641 ctttttttat tgcaaatgga aagagtatca ttgtacggat ttcgtttatt agttattttt
    35701 gtttttaagg aaaagctgtg tccgatattc ttttggagaa atcccttgtt ttttcttaaa
    35761 taaataactg aaatagttag ggtcattata accaatttca aaagcaatat ctgaaatacg
    35821 atagtctgat tgctgcaata atttttttgc taattcgatt ctttgttctg tcagataatc
    35881 gatgaatgtt tggttaaacg attgagaaaa aatcgtactg aaatgagagg gacttaatgc
    35941 aacttgttga gcgacccaag ttaaggacat atctggatcg gtaaaatttt ctttgataaa
    36001 atccaatgca tggttcaaaa ttggctgata tttgttcctt gaaggctgtg agggcagagc
    36061 agttaagaaa gaaatgaaca tataaactgt cgaacggtaa agcgagtcgt cggcgctgat
    36121 tgctaagcgt tgactggtgg atgtgcaatg aaccatttct tgcgggattt tcttttcttt
    36181 caggcagaca tgctggagta gcttagtcaa gacaaataaa cgatataatc gtgttcgagt
    36241 tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta gatacttcgt ttttcgataa
    36301 tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa tcaactggaa gtttcgcttc
    36361 ttgaatcaaa tcctcatagc tgataatttg ttctttaagg gaactggcgg tttcaagtat
    36421 catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt ctttctgcga caggaccaat
    36481 ggcgacagaa aaattatttt tttgtccctt ttctaattca tggaccaacg tttgggctac
    36541 ctgataactg gtctcgatca cattttcttc aagagaatca actattaaaa atttgatgaa
    36601 tcgagaggaa acagcagaga agatcacttg ttgattctcc ctaaataaaa acttcaaata
    36661 atcactgaga tgagcgtaat cttcaaagtc tgtactgact tggtttgctg ctaataatac
    36721 ggtcattttt ttccctgcta aagagcgatt gaaagattca gcaagtttca atgtttcact
    36781 gatcgtaagt gagcctttga acaaaccgtt caagaaatga ttttttttca attcgaaaac
    36841 aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct aaagcagtta ctgctttttc
    36901 tattgcttgt ttcaattcgc tacttttaat cggtttaagc agataatcat ctgcctgtac
    36961 ctggattgct cctttcatat aatcgaaatc gtcgaatcca ctaataaata tgagacgagt
    37021 ccaaggaagt agtttccttg cttcttttga aaaagtcaac ccgtccatga aaggcatttg
    37081 gatatcagtc agaatgatgt cgggctgtaa gtcgataatt gaagacagtg ccatctcacc
    37141 atctccagct tcgccgacat aagtgattgg ataataagaa ccaaggacag ttatttgttc
    37201 ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata aaaactttat acatgtttgt
    37261 ttcctccaat tgttttggga gatagaggga tcatcagtgt gacagttgtt ccttctcggt
    37321 atttgctgtc aatcgtgata ggtttttgat catttccgta ataaagaagg agacgcttgt
    37381 ttacgttgta aagtccgtag ccgatactga aatctgaatc gatccctttg gctaactctt
    37441 tacgtatttc tgccagtttt tctgcaggga tgccaatccc gttgtctata actttgaatt
    37501 ggatcatctc atcaattttg catgcggtaa tacgaataaa tcctttgtga cggacgtact
    37561 tcgttccatg gtatacagca ttttcaatca atggctgcaa gatcattttt aaaatagaaa
    37621 caggaaaaag tgtttctggt atatcgatct tatagtcaag catatggccg tatcttattt
    37681 ttaagatgac tagataatca ttgatatggc taatttcttt ttcaagagga atccagtctt
    37741 gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc atgggtcata gtcagagctt
    37801 cttcaaagca gtcttgttcg atcaaagaaa taatggcatc caaactgtta taaataaaat
    37861 ggggagtaat ctgagcttgc aatacacgaa cttcactttg tgctaaatgg tattgtttca
    37921 aagcgttctc ccgtaaagac tggtttagat cttccgccat tttattcatg ctagcggtaa
    37981 gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa gccaaggttc cctgaagaaa
    38041 gttgttctga catctcgatc agctgattga tcggttcttg gacctttctc tctaaaaagc
    38101 gacgattctt tttcgcatag aaaaaaatgg tactaagaac tccaagttcc actattgtta
    38161 atagaatgag cgagcggaca agtgtcgtat tttttttgct tgctaagtcg atctccacac
    38221 gaacaaaatc ttgtaagata tctgacagca gttgagtgac agaatctacc tgattgatga
    38281 tctcttcatt ggtatccata aaatcttttg ccaagatatt attgatcagc tcgttttgat
    38341 aatcttccag tgtatcgatc gtacgtagcg atacatctaa cgtactaatt tctttaagtg
    38401 tatttgtatt atttttgatc tctcgaatat cattcctaag ttcttctagg atattttcct
    38461 cattgaactc atctacggtt acttggccag aaatcaagtc ccacatactt tccaaaactt
    38521 tttgatcaac cttcaaagca attgcatctg ctttttggat atttgcgatc gtctgttgat
    38581 aaatcaaaag ctgttgcgaa tataacagta tgctcagtag caaagggata acagcaaata
    38641 gaagcatggc tttgtttgct tgggcaaaaa tctgttttat gcttaaattt tttgtcatga
    38701 tacttctcca gtcaataatt tctggttggg atgttagcta tattctgctg ggaaaagaca
    38761 gtctcggaaa taaaaatatc tttaggtaat gtttttcctg tttgaatatt tccaaaataa
    38821 cgagtaacgg tattggctac ataccagccg acatcaggtt tacactcgac tacacaattg
    38881 acgattcctg agcgtagctt ctcgatcata tcttcttgtc catcaatagt tacaatgatc
    38941 aaatcttctc caggtttgat tgatgtttct tttatcgcag ctaaagcacc gtgagtcatt
    39001 tcatcactat ggctgtataa tacatcgatt tcggataaat catttgtttc taaatatcgt
    39061 ttcatctggt cttttccttt catccgaata aaatcaccga caattcggtg aacaatagtc
    39121 atcggaggtt tatggtcgat ggttccatct ttttttaggg ttggtttacg attgattgat
    39181 tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt tctctgaacc agcaagttct
    39241 aggattctga tttcctgttt ctttgaattt gtgaagtgat tgctgacaaa taaacccgcc
    39301 cgatttcctt ctgctttgaa actggggcca atgtgggtga cgaaaagctc gggatcattc
    39361 gtttgaatat gtctgtcgac aagtatgaca gggatccctg ctcgctttgc ttcttttaat
    39421 acagagtccc acccggattc ttgcaaagga gtaaaaatga tcatatccac tttataggca
    39481 atgaacgtcc gtatatcttg gatttgccgt tcctgattca tgtagccatt tcggtagaga
    39541 acttggtaat cttctttttc aagcgcagtg ataattgatt cagtatgctt tttccgccag
    39601 ctactctccg ttcctgattg cgaaaaacca acgactagtg ggtcaggtgc ttcctttgta
    39661 ttaggtgtac accccatcat ttggtaagcg attacaacaa gggctaaaaa aaataaaaca
    39721 cgtttcactt taaatcactc catctggatt tgttagtact atcttatcag ataaaaggga
    39781 aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga aacttaaaaa aatccaagac
    39841 aaaaaaagta cacctaaaaa atttaaagta aatcccataa aaaaatcaat gttaacgctt
    39901 tctttattag ctatactcgg tgtatcaatt gaaatggggg ataaaaaatg aaaaacaaat
    39961 ttagaaagat tgttgggact atcgctattt tgaccgcaag cattctatta agtgcgtgtg
    40021 gcaattcagg atctgcagat gatagtacgg ggtatgtagg aatcgctatg ccgaccaaat
    40081 cagcagaaag atggatcgct gatgggaaca acatggtctc ggaattagaa aaactgggtt
    40141 ataaaacaga tcttcaatat ggagaagata aagtagaaaa tcaagtagca caaatagaaa
    40201 atatgattac aaaaggggta gatacacttg tgattgcttc tatcgatggt tcggctttaa
    40261 ctgatgtgtt agctaaagca aaagaagcag atatcaaggt gatcgcctat gatcgtttac
    40321 tgatgaattc agaaaatgtc gattattacg cgacttttga taattttgga gtaggtgtat
    40381 cgcaagcagc ttatattgaa gagcacttag gattgaaaga aggaaaagga ccattcacga
    40441 ttgaattatt tggtggctcg cctgacgaca acaacgcact aatcaattac aacggagtga
    40501 tgtctgtttt acaaccatat atggacaacg gtcagttggt cgtgccatct ggacagacga
    40561 gtttcagtca aatcgctacg cttcgctggg atggttctac ggcgcaagca aggatggata
    40621 atctgttaag cgcaaattat actgaccaaa cattggatgc tgttttgtcg ccatatgatc
    40681 caataagttt aggaatcatt tcgtcattaa aaggcgtggg gtatgggagt gaaagtaaac
    40741 ctttacctgt gattactgga caagatgcga cagttgctgg cgttaaatcg atcattgccg
    40801 gggaacaaac acaaacgatc tttaaagaca cacgtatctt agcaaaaaat acgattgaaa
    40861 tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa tgatactgaa acttatgata
    40921 atggggtgaa aactgtccct acgtatttag caaatacagt atctgtcgat aaagataatt
    40981 atcaagcaga gctgatcgac accgattatt ataaagaatc cgatctgaaa aattaagagg
    41041 aaccaaacaa ggaactaaag agatctaagt cagagagagg ataagaatta tggcggattg
    41101 tattttaaaa atggcagata tcaccaaaaa attttctgga atccgagcgt tagattgcgt
    41161 gaatctgatg attgaacgtg gggaaatcca tgcattgtgc ggagaaaacg gagcgggaaa
    41221 atcaacattg atgaatgtct tgagcggctt gtatccatat ggctcctatg acggggaaat
    41281 cttttatgat ggaaagctgt gtcaatttaa agatttgaaa gatagtgaag aaaaaggcat
    41341 cgtcatcatt catcaagaat tagcactaag tccttatctt tcaataaaag agaatatttt
    41401 tctcggaaat gaacaagcag aaagaggcgt gattgattgg gaactgacag aaaagaaaac
    41461 atatgaactg ctgaataaag tcggtttgtc tatcgacccg aatcttctag tatcccagat
    41521 tggcgtaggg caacagcaac tagttgaaat agctaaagca ttatcaaaat ccgtccgtct
    41581 gttgattttg gatgagccta ccgctgcatt gaatgaagaa gaaagcgcga atttgctgag
    41641 attgatccga gagttgaaag agcaaggtgt aacctccatc attatttcac ataagctgaa
    41701 tgaaatcgtg gatatcgcag atcgaatcac cattttacgg gatggacaga cgattgagac
    41761 actagaaaat gaaatgatca gcgaagagca tattattcgc gggatggtgg gcagagattt
    41821 agttgatcgt tatcctgaaa gaaaaccgga tattggagaa gtttatttta aagtagaaga
    41881 ctggacggtc tatcaccctc ttgatcacga gcgaatcata aacgaccaca tcaacttgca
    41941 tttgaaaaaa ggagagattg taggaatagc tggactgatg ggagcgggca gaactgaatt
    42001 cgctatgagt ctatttggac attcttatgg aagcaagata tccggacgta tattaaagga
    42061 aggggcagag atatcagtta agaccgttcc ttcagccatt gcaaacggac tcgcttatgt
    42121 ctcggaggac cgaaaatctt taggactgaa tctgctgatg gatattcggg aaaacgtgac
    42181 gctgagcagt ttggataaaa taagtcaaaa aggagtatta gataaagaaa aagaagtaac
    42241 tgaggcagaa aatttccgga aaaagatgcg tataaaaaca aactccatcc atcaaattgt
    42301 cagtagtctt agtggtggga atcaacaaaa agtcgtttta tccaagtggc tgatgacaca
    42361 acccgatatt ctttttttgg atgagccaac ccgtgggata gatgttgggg caaaatatga
    42421 gatctacacg attatcgaag aaatggcagc aaatggcaaa gctgtctgtc ttatctcttc
    42481 tgaacttcct gaaatattag ggatgtgtga tcgaatctat acgatgaacg aaggacgtat
    42541 tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc ttgatgaaat taatgacgaa
    42601 agaagaggtg ggttaagttg gaacaggcaa aaaatcttac ggataaaaaa gagaaaaaac
    42661 taaatttgaa aagtagagca gctgatcttt ttggtcgcta cagcatggtg atcattttag
    42721 cgggactact tattgcgttt caattgatga cggatggtat tttctggcgt ccattgaata
    42781 taactaacct tgttctgcaa aatagccata tattagtact agctgcaggg atgttattag
    42841 ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt gatggcgttt gttggtgcaa
    42901 ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg gatgacagtt atcgcatgtc
    42961 ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg ggtagcttat gcagggatac
    43021 cggcgtttat cgtgacttta gcaggattgc tgatgtttcg tggactgaca caagttgttc
    43081 taggaggcca atctctagca ccttttccag ctgttttcca aaaaatgtct acgggttatt
    43141 taccagactt aagcgaagga agcagccttc acttcttgac attgatttta ggaatgatca
    43201 tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa tcgtcggaaa aatcatttat
    43261 ttgaagtgga atctccaaca gctttcttgg taaaggcggt atttacagca gtcgttgtac
    43321 taggaataac ttatatcttt gcctcttatc aagggtatcc gattattttg atcattcttg
    43381 gtttgatcgt tgcagcatat gggtttttga caaataaaac agtagcaggt cgacagattt
    43441 atgcgacggg cggaaatcga aaagcggctg aactatcagg gatcaaaaca aagcgaatca
    43501 cgttctgggt attcgtcaac atgggagtca tggcagcttt agctggatta gttttagctg
    43561 ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat ggaactggat gcaatggcgg
    43621 cagtatattt tggtggtgct tcgacttccg gcggcattgg aacaatcatg ggtgcgattg
    43681 tcggtggctt ggtcatgggt gtattgaaca atggcatgtc gattttaggc gtcggggtag
    43741 actggcagca ggcaatcaaa ggattgatct tgcttttagc cgttgtgcta gacttgtata
    43801 ataagaaaaa acgaacaacg taggagaacg ccggttattc agaaaaaaga ctgtgacaag
    43861 acatttgtca cagtcttttt ttcgctaaaa gcgaacattc attgtttcgt ttgtatagac
    43921 taaaaataat atatgttttt ttaccattcg tataaattct ctttttgctc ttgatttttt
    43981 tgcttaattg agttaaatta catagggcgc taaaaaaagc cttgattaaa ttaataatgt
    44041 tcgtgttttg ctggatgtga acatcaggag gataatgtaa tgaaagtatt tgattacgaa
    44101 gatattcaat taattcctaa taaatgtatc gtaaatagcc gttctgaatg tgatacaacg
    44161 gtcacattag gtaaacatac attcaaaatg ccagtagtgc ctgccaacat gcagacgatt
    44221 attgatgaaa caatcgcaga attcttagcg gaaaatggtt atttctatat catgcatcgg
    44281 tttgatgaag cagctcgaat tccgtttatc aaaaaaatga aaaagcgtgg attgattacc
    44341 tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta tagagaagtt ggcagaagaa
    44401 tcgctaaatc ctgattatat cactatcgac atcgcgcatg gacatgctaa ctcagttatt
    44461 gatatgattc agcatattaa aaaatatttg cctgaaactt ttgtgattgc cggtaatgtt
    44521 ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg cagatgcaac aaaagtcggg
    44581 attggtccag gaaaagtatg tattacaaaa atcaagacag gctttgggac tggaggctgg
    44641 caactggcag ctcttagatg gtgtgcgaaa gcagctcgca agccgatcat cgctgacggt
    44701 gggatcagaa cacatggcga tattgcaaaa tctgtccgtt ttggtgcgac aatggtcatg
    44761 attggttcat tgtttgccgg tcacgaggaa tctcctggcg aaacaaaagt cgaaaatgga
    44821 atcgtgtata aagaatactt tggttctgct tcagaattcc aaaaaggcga aaaacgaaat
    44881 gttgaaggaa agaaaatctg gatccaacac aaaggatctt tgaaagatac actagtggaa
    44941 atgcaacaag accttcaatc atctatttct tatgctggag gaagagatct ggaagccatt
    45001 cgaaaagttg actatgtcat cgtgaaaaat tcgattttta atggagacac aatctaaaaa
    45061 ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc attaagtaat aagaacagcc
    45121 aaacaaaaat agttctttat atgttttgtt tggctggaat tattatcgca gatacaagct
    45181 tttgaacatc attattcaga ataagggact gtgataagat ttttgtcaca gtcccttatg
    45241 ttttgcaaaa aaagtttttc ttttttctcg taaattcggt aaaatcaaaa gaaaaaatag
    45301 acaatagaaa agagaagctt atgtgggaaa aagtagagaa aaaacaagga ccgatttatc
    45361 gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg aaggatcaat cctggaagtc
    45421 aacttgaatc agaacgaaaa ctagggcaac tttttggtgt gaatcgttcc accgttgtcc
    45481 atgcattgga agagcttagg gagcttgggg tactaacgag caaacgtggc agcggatggt
    45541 ttgttaatca gactgaatgg gggaaattcg ctgttccaag aatcgattgg cggcaaatga
    45601 tctctcctcg ttatgagcag acggactggt atgagcaaaa aataagagaa gcaaagcaga
    45661 tccaaaaaac atcgtttctt gatttatacg ctagcgagat gccagatgag cttttgccga
    45721 attttgagtt tccttcttat tctcttgaag aaatcttagc ggaagaaaaa gaaatggatc
    45781 ttttaggcta tactccgtta cgtaacaaaa tcaaacggta tttggaaagt aaatttgaat
    45841 tggcattttc ccccaaccag cttcttgtga ctggtggcgg tcagcaagca atctttttga
    45901 ttttacaaac gattctttca gctggagagg ggatagctgt agagtcacct tctttttttt
    45961 accgattacc tcttttcaaa gcttcaggaa cgcgtttatt tgggataccg atggatgaag
    46021 aagggatcga cttagaaaaa ctgaaagaat cgatccataa aaataaattg aaagcagtgc
    46081 ttatcaaccc gaattttcaa aaccctacag gaaaagtgat gagtcaaaaa cgacgagaaa
    46141 agctagtaga attgtgtcga cagtatcggc ttccaattat tgaagacgat gtatttacgg
    46201 atctttcatt tctaaaccaa gaagaagtcc ttcctatacg aacgattgat ccggataatg
    46261 tgttatacgt cggttcgtta tctagggttt taggaaaaac aacgaaaatc ggttgggtga
    46321 taggacctga gacttttatc tcgcaactag ctcaagcgca agaaatgatg gagttttcga
    46381 tgaatatcct tacacaaatc acagtggcta atgtatttaa tgaagcaatt gatttgaaaa
    46441 tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact gataagcgct tggggagatt
    46501 cacaatcgtt tttcaagctt cattcaattt taggtggtta ctatgcctgg attacttggg
    46561 atgggaaaaa actagacccc gaactagcag aaaaagtagt agatatgggt cttggaattg
    46621 caccaagtct actttttggg caagatataa atggaatcag aatcaattac agtaggctgg
    46681 atgaaaacca aataccgttg ttttattcaa agatgaaaat tctagaaaag tggttaacag
    46741 aataatttca caaagtaaat agattaaaga atataacagc ttggatttaa atttcaagct
    46801 gtttcttttt tttcggaaaa agaatacgat ataaagaaac taagaaaaaa ccattatttg
    46861 tacgtccgtt cacgatgtgt aaataaaata aatgtttgca acaaaactgt ataacaccaa
    46921 cgtttttaaa tagaaacaga tggttgtaag tttgattaga aaatagaaaa aatgcagatg
    46981 aaaaataaaa cgctttcctt attgtgattt tattcactaa tgctgttaat atgcggattg
    47041 gcataatttc ctttcatcgt gaaaatttgt gcttttagct tgtatttctc ataaatccat
    47101 gataatttat taatgaagac ggttaaatag tgatacagtt ttattcactg tttcaatcgc
    47161 agaatgaaga gattttctta tagatgagag aggaatgtgt gacaaatggc aaacaaaaaa
    47221 gcaccgatcg acttccaagc actgctagat gaagtcaatg cagatttccc agtatatcaa
    47281 gcacttgatc aagatggaaa cgtagttaac aaagatttag tacctgattt atccgatgat
    47341 gaactcgttg aattaatgac tcatatggta tggtctcgtg tattagacca acgttcaaca
    47401 gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa ctgctggaca agaggcaagt
    47461 cagctggcta gtgcttacgc atttgataaa gaagatgttc ttcttccagg ttatcgggat
    47521 gtacctcaac tagtaaaaca tggtttacct ttatctcaag cttttttatg gtctcgagga
    47581 catgctgcag gtaattctta tccggaagaa ttgaaagctc taccaccaca aattatcatc
    47641 ggtgcacaat atgtacaagc agccggtgtt gcattaggtt tgaagaaacg aaacaagaaa
    47701 aatgtcgtct tcacttatac tggtgatggc ggttcatcac aaggtgattt ttacgaagca
    47761 atcaatttcg ctggcgctta ccatgcaaat gccgtatttt atatccaaaa caacgggtat
    47821 gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa cacttgcaca aaaagctgtc
    47881 gcagctggga ttcctggtat tcaagtcgat ggaatggatc cgcttgcagt atatactgta
    47941 tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac cagtcctaat cgaaacactg
    48001 acttatcgtt atggaccaca tacactatct ggtgacgatc caacccgcta ccgtacaaaa
    48061 gacacagatg acgattggca gaaaaaagat ccattgatcc gcttccgtaa atatttgacg
    48121 gaaaaaggac tttggtctga agaaaaagaa gaacaagtca tcgaagcaac taaagaagaa
    48181 atcaaagcag ctattgctga agccgacaaa gtaccaaaac aaaaggtttc agatttcttg
    48241 aaaaacatgt tcgaagtatc tccacaatca atcaaagaac aaattgcaat ttatgaagcg
    48301 aaggagtcga aataatcatg gcacaaaaaa caatgatcca agcaatcaca gatgccttag
    48361 cacttgaact agaaaatgac gagaatgtcg ttgtttttgg tgaagatgtt gggaaaaacg
    48421 gaggagtttt ccgggcaact gaaggattgc aggaaaagtt cggagaagac cgagtattcg
    48481 atactccttt agctgaatct ggaatcgcag gattgagttt cggtcttgcg ttagaaggat
    48541 ttcgtccagt tcctgaaatc caattctttg gttttatttt cgaagcaatg gacgaagtag
    48601 tagctcaaat ggctcgtaca agatatcgaa tgagcggcac tagaaatcta cccatcacaa
    48661 ttcgttcgcc atttggtggc ggtgttcata caccagaatt gcattcggat aatttagaag
    48721 gtttgatcgc tcagtctcct ggtattcgag tagtgattcc ttccaaccct tatgatgcaa
    48781 aaggactatt gatttcttct attagaagta acgatccggt tgttttccta gaacacatga
    48841 aactatatcg ctcattccga gaagaagtgc cggatgaagc ttacgaagtt cctttggata
    48901 aagcagcagt tactcgtgag ggaacagatg tatctattat cacatacgga gcaatggtgc
    48961 gtgaagcaat caaagcagca gacaatcttg caaaagaaaa tatatctgtt gaaatcattg
    49021 atcttcgtac agttgcgcca ttagatgtag aaacgatcat tcaatccgtg gaaaaaactg
    49081 gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg cgttgccgcg caagtagttt
    49141 ctgagatctc agaacgcgct atcctttcat tagaagcccc aatcggacga gtttctgcac
    49201 ctgatacagt cttcccattt ggacaagcag aaaatgtctg gttgccaaat gcaaaagata
    49261 tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa gaagggacga aacaaagtca
    49321 tggcttatca atttaaattg ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca
    49381 aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta gaagttcaaa
    49441 atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa aacgtgattg
    49501 ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat gctcctggac
    49561 acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa aaagtggaaa
    49621 catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta ttggctatgc
    49681 catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta actgcaactg
    49741 gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt ggtccaagca
    49801 gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca gctcctgcag
    49861 cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga gacttggaag
    49921 aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc aacagtaagc
    49981 atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta tgggataatc
    50041 ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc ttgccatatg
    50101 tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca tctatcgacg
    50161 atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca actgatacgg
    50221 atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg tttgctattg
    50281 cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct gcagaagata
    50341 tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt tggtttacac
    50401 cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca caacaaccaa
    50461 tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca ttaagtttcg
    50521 atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc aaacgtcttt
    50581 tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt tggagatttt
    50641 gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt agctgccatc
    50701 cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat tggcggtgtt
    50761 tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca ccattatcaa
    50821 gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact agattttgca
    50881 aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg tgttggtttc
    50941 ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt agatgatcac
    51001 acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa cgcaatcatc
    51061 gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg tgtgttagat
    51121 tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat cggtggcggt
    51181 gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt aacgattctt
    51241 gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt agtagaagat
    51301 gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga agcagtcgat
    51361 aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc cgttactgct
    51421 gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg cttagaacaa
    51481 gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg acgtacgaac
    51541 gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc acacaaagcc
    51601 agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc tgtagattat
    51661 aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg tatgacgatc
    51721 aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt ttcagggaac
    51781 ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac gacgatcgaa
    51841 gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat ggtctctgaa
    51901 ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac gattcatcct
    51961 catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg tttaccaatc
    52021 catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc gttttgtttt
    52081 ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc ttggtttatt
    52141 accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag atgcaagaat
    52201 atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta atgaagatgt
    52261 gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt ttgaagactt
    52321 atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg ggacgggaat
    52381 ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa aaaaatccaa
    52441 acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc atatcaagtc
    52501 ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa caatctcgca
    52561 aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga attttctaat
    52621 cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag aagggtgtaa
    52681 tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg gcaccttgaa
    52741 ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat ccggcgttgg
    52801 aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg gaaaaggaat
    52861 aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct tatcggaagg
    52921 cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc gagaaattgc
    52981 ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag tggcaatctt
    53041 gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg cagcgggaaa
    53101 tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc ctttgacatt
    53161 tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa tcgcagacct
    53221 tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat aaaaacgagc
    53281 aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga aaaaagtctg
    53341 ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa aaaggagtta
    53401 gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca cgttgaccac
    53461 ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga cgcacatacg
    53521 caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg tatcacgatt
    53581 ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat ggatactcca
    53641 ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga cggcgttgtg
    53701 ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt gaaaaaagca
    53761 ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc ttctgctcgt
    53821 cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc agatgatgat
    53881 cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag cttgtcagat
    53941 gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat tgaaaaaatc
    54001 cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt acttgactac
    54061 aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat caaagtagga
    54121 gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt aacgaaatta
    54181 tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg agacttgatt
    54241 gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt ggatcatcaa
    54301 gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt cttagttaat
    54361 aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat tgaagaacgt
    54421 ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa ctctccagat
    54481 gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga aaacatgcgc
    54541 cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga aatcgacggt
    54601 gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata tatgggtagt
    54661 gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca tacaggaaac
    54721 ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta ttcaactgaa
    54781 ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca atatctgcca
    54841 atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat cgatacagga
    54901 aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt cgtagaacca
    54961 ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa tgatttgact
    55021 gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa agaccaaaca
    55081 tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt cttgaatgat
    55141 gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat tttagagaaa
    55201 aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg aagagagaaa
    55261 ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc tgtggagaag
    55321 tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta aaagactttt
    55381 aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca cgaaaggaga
    55441 tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc gggaagatga
    55501 acgacttatt aaaacaatac tttggttatg atgagtttag acctggtcaa aaagaaatta
    55561 tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga agtgggaaat
    55621 caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt gtgtcccctt
    55681 taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata cccgccactt
    55741 ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa atcgatagac
    55801 agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat tttatccaag
    55861 caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt atctctcagt
    55921 gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat caactgccaa
    55981 atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct gctgacataa
    56041 aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa cgagaaaatc
    56101 tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa tatttaaaga
    56161 tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta gaccgtctct
    56221 atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt ctaaatgaga
    56281 atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg attgtagcga
    56341 caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc cattatcaaa
    56401 ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga gatggtcttt
    56461 ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag ttttttatcc
    56521 agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta aaagcgatga
    56581 cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat tttggcgaga
    56641 caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata gtagaagtaa
    56701 cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac tatggtaaac
    56761 aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct ttaggttttg
    56821 gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg atgcagttaa
    56881 ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat cctgttttga
    56941 aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat cgaaaggaac
    57001 ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa gtgctgcggg
    57061 aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta ttttcagatt
    57121 ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg cttcagataa
    57181 aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct cggataaaaa
    57241 atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat gaataaaaac
    57301 aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat aattaaggaa
    57361 ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga tccaagtatt
    57421 aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca gtctctgtat
    57481 ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct tttcccggca
    57541 agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc tgatgttaag
    57601 tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa tttatgataa
    57661 aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag gcatctatta
    57721 gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat catggtatat
    57781 agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc agtcattaac
    57841 cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa aatgaaaaca
    57901 gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac gattttgctg
    57961 ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct gcaaattgca
    58021 ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta cctgtctctg
    58081 actttatcta aaagacaaaa cagtgtacaa aaagattttc ttgggactgt gaaacgtcca
    58141 cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt tggtaatgcg
    58201 gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa ttatgtgtat
    58261 actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg gctgatcaat
    58321 atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg atttgctatt
    58381 taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa cggctactat
    58441 gccatgttca acggaggact atttggcagg ggattaggta acagtatcca gaaaaaagga
    58501 tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga actgggagtg
    58561 attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat tgtccttgta
    58621 ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg cgcaatgttt
    58681 ttgatccaag tatttgtcaa tcttggagga attactggcg ttattccttt gacagggatc
    58741 acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat ttgtgtcggc
    58801 tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata ataaaaaaag
    58861 atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa tcgctgtacg
    58921 tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg cagaagaaga
    58981 tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac aaggaaaaaa
    59041 accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag aatgcggagc
    59101 tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg cgcaacggtg
    59161 cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata tttttggaga
    59221 taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc caggcacaga
    59281 tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg gttatccgat
    59341 tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc acgatgaaaa
    59401 gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct ttggtagtga
    59461 tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac agattctcgg
    59521 ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc agcgccgtca
    59581 ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac gtcaaaaaat
    59641 ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag gtacagtaga
    59701 atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg tccaagtgga
    59761 acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac tgttgattgc
    59821 tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa ttaaattaaa
    59881 tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact ttttaccaga
    59941 cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc tggatgtcgg
    60001 aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag taaaagtatg
    60061 tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct tgaaagaatt
    60121 tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca cacatcctga
    60181 attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat tatttgaatt
    60241 tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa ttactgtgaa
    60301 tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac gtatgcctaa
    60361 agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg cgaagggtgc
    60421 cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg atacgacatt
    60481 tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt tcaagcagat
    60541 tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt gggggggagc
    60601 aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt tgagaaaaat
    60661 tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa atgccgttgg
    60721 gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag cagcgcaagg
    60781 aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg aaaaaagtat
    60841 ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata ctggcgatat
    60901 caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg caaaggaact
    60961 agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc ttaaaccgca
    61021 ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa tccatctgca
    61081 tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa aagcaggagt
    61141 agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc ctagcatgag
    61201 cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga ttgaaaatgc
    61261 acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt ttgaaaacgg
    61321 cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac agtattcgaa
    61381 tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa tcaaacaaat
    61441 gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat catctaaagt
    61501 agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag atatttatga
    61561 aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag gagaactagg
    61621 gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag gcagacctgc
    61681 attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag taaaaaaaga
    61741 attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct atttgatgta
    61801 tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg ttacattact
    61861 ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg tacaaatcga
    61921 acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata tcgaagggaa
    61981 tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca aagataattc
    62041 gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag aacaaattgg
    62101 agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata acgttaaaaa
    62161 aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg aagcacgttt
    62221 tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt ctggtgacct
    62281 tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa aagactgggt
    62341 ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc agtcttgttt
    62401 ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca aatgacaacg
    62461 tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa accgatcgat
    62521 cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt tggttttgaa
    62581 acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat ccaagacagc
    62641 agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc gttttattta
    62701 gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt cacttttgag
    62761 taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta tcgtccgcta
    62821 attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac aaacggccta
    62881 ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata tcaagtgttt
    62941 ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc aatcaatcgc
    63001 gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga cgaacttccc
    63061 atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca tgattttttg
    63121 acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa atcgctaggc
    63181 agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa gttaatcagt
    63241 aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga cgctactttt
    63301 tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga cccgggaacg
    63361 gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca agaagaaaac
    63421 ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg aggatcaatg
    63481 cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc ttgaacataa
    63541 acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct tgtctaagaa
    63601 agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc gtgaaaaaaa
    63661 acgagctgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg cagctttccg
    63721 atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac ttgccgaaga
    63781 agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga aaaaacactt
    63841 tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata acaaaacgac
    63901 gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa aagttcggct
    63961 tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat gaagagacat
    64021 tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta gaacgttctt
    64081 accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca gtattaaaag
    64141 acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa catctttaaa
    64201 aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga tttttgatca
    64261 ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag tgagtagatg
    64321 cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg ggcgaacacc
    64381 agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc atattttgat
    64441 ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga agcagtatct
    64501 agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa aatcatcaaa
    64561 gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact tgatgcggac
    64621 aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt tcttgatccg
    64681 ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact gggacttttt
    64741 tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc agaaactgtg
    64801 gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac tatctataga
    64861 aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct tttacaaaag
    64921 gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta attggtgttt
    64981 ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca ttgatcacaa
    65041 aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa ttgacggtag
    65101 aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt atcaaagact
    65161 ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa ttggaaactg
    65221 tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta aaagaagtac
    65281 tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa gctttagctg
    65341 gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat tatcatattt
    65401 ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga atcaccggga
    65461 gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa aggttctggg
    65521 tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc tttaaaagct
    65581 aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg ggcgacaaat
    65641 gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc agcaatcgaa
    65701 caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt atatgtcatg
    65761 agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac agtaacaaaa
    65821 gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa aagccaaaaa
    65881 gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac agcttctggt
    65941 gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct tactgaccat
    66001 accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg tgggccatca
    66061 gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa cttgcgacat
    66121 ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg ccgaatcgga
    66181 ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt ctttgcacca
    66241 gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac caactacgaa
    66301 gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc agtaaaaaca
    66361 gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat taaagagggg
    66421 ttgtgacacg agttctgtca caacccctct ttttcgtcaa aaatcttcac gataaaaata
    66481 aaaacaaaag aaaaaattga cgtaattaga tgttgaaggg acgattttgc cagagctcac
    66541 tgtttcttca attttaaatg aaaggagtaa tgaatgattt ttactggtca ttctttgaaa
    66601 aaagaacaat gatagaaaaa atcagcaaga aaatactagc ttcacccaaa ttgatcattt
    66661 ggatgtctat gatagttctt atcttttgta tcgcaagtgg ttttttatta tcaaatttgc
    66721 tattttatag agaaacagaa gagactgctg caaaagaaat actttcttcg tttagttcca
    66781 gtggagaaga tccatcagct gaaggaaacg atgtagaaga ggatgctcgt ccaaaggtca
    66841 tgtacaccga tatcaaagga agtgtgaagg agcctggtat ctattccttt tcttcagaag
    66901 aacgggtcta tgatgtacta aagcgtgcag gtggattatt agaagaagcg gatagcgatc
    66961 gaatcaactt ttctgcgaag atagaagatc agcaagtcct atatatccct gctgtaggtg
    67021 aagagctgcc agaacatctt gatcagttgg catcctcgga aggaaaacag cctacagcag
    67081 attccgagcc tcccaaaata aatatcaata cagccactcc atcagaactt cagcagattc
    67141 ctgggatcgg atcagtcaaa gcgcaagaaa tcattcgatt tagagaagaa aacggatcct
    67201 tccagaaagt ggaagacctg caggagattt ctggtatcgg tgaaaagaca gttgaaaaac
    67261 taaaaaactt cgttacaatt aaatagaatg attcaaaatc gactggcacg agcaataaat
    67321 ggacgctaat ggatactaag aataatccaa ttctaagagc ttggcaggac gaggaggtag
    67381 tatttttgga taggaaatag cttgattgtt cgcaaagaaa cattaaaaaa accaatgctg
    67441 aatgtctatc tccaaaataa aatatctggg attcatatta tgaatacggc tgtcagcggc
    67501 aataacagtc aagctctacg agaacgcttt gccaaagatg tacttagcta tacagcagat
    67561 aaagtattta ttctcattgg gacgaatgat ctagcagagc ataaacaact ttctaaagaa
    67621 acgtaccaaa aaatctgcag tggatgatag ttcagctgaa aaaagactat agttctgatc
    67681 atgctttctt tatcacgcca ccagcagtcg atgagacaaa acaaaaatat cggaataaca
    67741 agttgatcaa agaatatatc tctgttctca cagaagtagc aaaacgccat gattgtgaag
    67801 tatcgatttt tatacggaat ttcttgaaca aatggattcg aagaattttt ataatgggct
    67861 aatggatgac ggacttcatt tcggcagtga agggtaggat cttttgtcag acaggatgat
    67921 tcgttatatt taaagaatat tttgtttaag caatgagtac tttttaatca acttgaaaaa
    67981 acggaggaat ataaaacatg ttagaaaaat cttcaaaagc atgcgatacg aataaagaaa
    68041 aagttactga taagtcacat aatgaacgca ttccttggga ccagtacttt atggctcagg
    68101 cagtactgtt atctttacgt agtacgtgta cacgtttaga agtaggagcg acactcgttc
    68161 gagaaaaaag gatcattgct ggcggctata atggagcagt cagtggagat gtccactgca
    68221 tagatgaagg gtgttacgtc gtggatggac actgcttgcg aacgatccat gcagagatga
    68281 atgcactcct acagtgtgca aaacttggta tcccgacgga aggttcagaa atctatgtca
    68341 cacattttcc atgtttggcc tgtacaaagg ctttgttgca agctggtgtg aaagggatca
    68401 attatctcca tgactatcga aatgatcctt atgcccaagc gttgatcgaa caattaggtg
    68461 tatctgtaca ccaagttgct ttagactcac agcatttttc aaaacttcaa aatgaattaa
    68521 caggaaaaca tgtctagcgt tttagaaagg catgttcgaa atcggttgat ttttccggca
    68581 attacgtcga tgattatctg tttgttgtat tacactgaca attggggtta tcgtttgctt
    68641 cttgccggaa tttttttatg gttttcgcta aaagaaggac gttttatcgc gtacttgtgt
    68701 attttgtgta gcataacggt atccatttct tataggctac aagagtattc atttttagag
    68761 gaaaaaacaa catctgcgca aattactgta tttacagata cgattcgtgc aaatggtaat
    68821 tttttgacaa tggaaggaag gttatcagag aataaacaaa agctccagct ttcttatcaa
    68881 gtaaacacag aagcagaatt gaaaacatgg cttaacttcc gaggaaaggg aatagaattg
    68941 actgctgaag gcgagttcat ctctccagca aaaaagcgga atctttataa ttttgaccaa
    69001 gaagcttact tcaggaacca tagaatttct ggacggttcc aaattcaaaa gattgaacag
    69061 atcaccatgc aaaatcactg gcgaaactgg cttcagagaa aaagaggatc ttttatctcc
    69121 tttgtccaat ctgaatttcc gcaaaaaaca agtgtatata ttaattcttt attatggggc
    69181 tataaagatg caggattcag agaaccagaa gaaattttta gggagagtgg tttgctgcat
    69241 ctgttcagtc tatcgggtct acacatccaa ttttatttag ggtggctgta ttatttattt
    69301 cgacgtatcg gatggccact acacgtcagt attattccgt tgagtctact aactatctgt
    69361 tatgtttcta ttgcaggaag ttctatttct gttttgcgtg ctagtttgct gtttttattg
    69421 cgattgctag tcaaattgct gaataagcat tattccacca tggacttatt tgcagttgtc
    69481 ttttggcttc ttttactatt tgatcctcga tttctttttc atgcgggtgg acagcttagt
    69541 tttttcatga gttttttgtt tatcctgatt tcttttgatg gagattggtt gaaaaaaacg
    69601 gcctctcacg tcctgtttac tatgatcacg atgccgttga ttgtatggca tttttatgag
    69661 tggcctattt taggtagtct ttttacatta ctgattgcac cggtattcaa gtttcttttt
    69721 cttcctggtg tgttatttct cacactcttc aatcgctggc tgccggaaac tttacttttg
    69781 ctgatagaag agggattaat cttatttgag cgaataatcg atttttcttc agggtcgtct
    69841 ctcattatag gacgtttgcc ccttgtgcta tctgggatgt atattttcgg attactgatt
    69901 tgtatggata ggttgaaaga acaacctgtg aaacacttgt tttatgttgg tcttttttct
    69961 tttatttttt tgactttgcc atttttacgc ttttcttcaa cgatcgcttt tatcgatgtc
    70021 ggtcaaggag acagtatctt tttgcaaagt ccttttcgaa aagaaacgat tttgatcgat
    70081 actggaggtc agttacactt tgaaagagaa aagtgggcgc aaggtatgat acgtcctcct
    70141 gctgaaagaa atatcgttcc atatctaaaa ggtcagggga taagtgtaat cgataaactc
    70201 atcttgacac acgacgatac ggatcatgtg ggagaattac ccacgttatc tcagcatttt
    70261 actatcaaaa aaatttatat cggttggggc gctggacgaa atgagccatt acaaaggcat
    70321 ttatctgaag ctcaaaaaaa tggtactgag atcattgaaa tcaaacatgg ggacaggatc
    70381 agcggttatt atgatcttta tgtattgact ccttttgaaa agggagaggg aagaaatgaa
    70441 gattcgattg gtctatggat ggaatataac aataggcgct ttttattttt aggagatttg
    70501 aatcaagcaa tggaaaaaca attgcttttg atttatccta atctgaaagc cgatgtagtc
    70561 aaattaggtc atcacggtag ccgtacgtca agtaacacag attttctttc ccatattgaa
    70621 gcaaaacatg ggattatatc ctgcggcgta aataatcgtt atggtcaccc gcacagcgaa
    70681 gtattggaga cactagaaga aaatcagata aaaacatggc gaacggatca acaaggaatg
    70741 atcacctatc gctggcatcc agtttttcat cctcatgggc tagtggaaac aatgatagac
    70801 tagtaattct catctgctca tggtaggata atttttgaaa gtggtgagta atttgagtat
    70861 acaagcagag ttacaaaaaa tacgtaaaga aaaacttgca tcttgttact tgattttagg
    70921 aacagaaaag tttctccaag atcaagttcg gacagaaatt gtcaaaaaaa tccaattaga
    70981 gggcgaagat gacttaaatt ttttaagttt tgacatggaa aatgcaagtt tagatgaggt
    71041 agtagctgaa gcagagacgt tgccgttttt cggagatcaa cggttagtat tcgtagagaa
    71101 tccttatttt ttaacaggtg aaaaagtaaa caatggaatc gaacaaaata ctgatttatt
    71161 gacggcttat ttgaaagaac cattagaatc gactgtatta gtattctttg cgccatatga
    71221 aaagttggat gaacggaaaa aagtaacgaa acaattgaaa aaaacagcaa ttatcatcaa
    71281 tgtccaacag ttgaatgaaa aagaagtacg tcaatatctg atgaatacct tagagaattc
    71341 ctcaatcaaa atggaacgaa gtgcaattga tttattcttg aggttgaccg acttagattt
    71401 atccaaaatg atgagagagt tacagaaatt ggtcctttat ggacaaaatc aacagcaaat
    71461 cacggtaaga gaagtagaag aattagttcc taaaacgtta gaacataata tttttgacat
    71521 gacccaatat attttaaaag ggaagacgga acaagctttg cgtttatacg aagatttagt
    71581 tatgcaaggg gaagaaacaa tcaaaattaa tgcgattttg ctttctcaat tacgtttatt
    71641 tttacagaca aaatttcttg taaagattgg ttatcagcag gcaaatattg ctgaaacatt
    71701 gaaaatccat ccatatcgtg taaaacttgc catgcaggaa gtaaaaaaat tcgatgaaca
    71761 tttgctggta cagttgtttg atcaattagt tgagatggat tatcaaatca aaacgggaca
    71821 aatcgaaaaa gaattaagtt ttcaactatt cgttttgcgc acagggcagt tgttaagaaa
    71881 tcgataagaa gaaagacgag ggcaaagcat gcgggaaggt cgtttgtttt tgtccttttt
    71941 ttgacaaata aaaaaatcgg ccgaagccga ttcttttatt tagcgatttt tttgcttaaa
    72001 cgagatttgt cgcggttagc tttgtttttg tggattagac cttttgattc agccatatca
    72061 atagctttaa cagcttcttt atataacgca tctacgttgt cagcacctga agctacagca
    72121 tcttcaaatt ttttgattgc agtacgcata gcgcttgttt gagatgaatt tttcacatta
    72181 gcgttttcgc ttgtacgaac acgtttgatt gcagattcaa tgtttggcat tagtttcacc
    72241 tccgataact taagttctta cgcgtgttac cgcataattc aacattcatt attataccta
    72301 aaggcagcgt gctttgcaat atgaacatga caagtttttt tccttaacag tcttttatta
    72361 ggattttttt tcagtaaaaa cggatagtac aagctgaaaa aaatcaaaaa gacgctattg
    72421 tgggaggcaa tagcgtcaaa ccaaactaga tttttattta tctatttaaa caaagtttga
    72481 atgggaatgt ttggtactaa gttattatat aacaaagaga accgtttgca aagttttttt
    72541 tgaaaaggga tacgattccc tgttgttctt tgtttttcta ttaagaaact gcagttattt
    72601 tataaccagt atcctttgat cagtaaaggc tattctggtg taccgattat tttaatgtat
    72661 tcatcgatat tttttatcaa catttttttt atgaccaact ggttccgacg gttccatttg
    72721 ccacttactt ccagcacata tttatttagg ggcaaacgta agatatattt tgccaaatag
    72781 cgatctttaa gcaggccatt gatcacacgg tcctcaagct gcaagttgat cccagtcagc
    72841 atcattggct gttcttgtaa aacgtacgta tcaattaaaa gaccttcaaa agtttccaca
    72901 agcgtcttcc tttcttttca aagtaacctg aaaacaggca ctaattcttc cattttgata
    72961 ttcgttgaag tggatgcgat cattctttct tttgtccact gtaatctagt ataacaaaaa
    73021 agagcagaag agccaaaaag aaaaaagagc atcgaattct ataggaagtc tcattggcac
    73081 ggcctaaatt attacaaaac attgattaaa aaaagcccct gcatcgcagg agcatcccct
    73141 atatcgtttt aataggtcaa tcaaaaagca gtatcaaaca cattttgtat caaatcagga
    73201 aataatagat aagctaagcc cagaatcaaa agtaccgcta gaagaaacca gccgattgtt
    73261 cctatgaaat actttaattt ttcgaacatt gtatcacctc gttgtcagta tatcacggat
    73321 cagtaaattg ggggtgttaa gaatctccta aaatagacaa aatttgttct attttcctaa
    73381 agcaaatact tgtaagatac agtaagtgat accagaagca atgaccggtc cggcggcgat
    73441 tcctcttaag aagacaacac ctaaaatcgt gccgaaaaca agtgcaacag tgatttgtgg
    73501 atcagaagca atcaatccta cacccttgga agataagaca gccactagcc caccgcaaaa
    73561 aacagctacc cagccaatag gggatttaaa ggcttctaat agatcacgta gaccgatttc
    73621 tcctgttgcg atagggatta gaatagccgc tgtgatgatc gtcaccccaa tattgattcc
    73681 tttgccttga agccaaggga aaaaggaacg ggaggctggt atgagcttca taatcaaaac
    73741 aaaagctgcc gctatcatca gactttgatt tttagctaaa attgctacaa gtaaaataat
    73801 tcctaaaaaa agccaacttt ccatgaaata tattcctcac tttcttcgaa acaatcataa
    73861 catgttttta gaaagttaca aaagtaggaa ttcatccttc aagacctatt cataagctgt
    73921 ttttttcata aaataaacaa aatcataaaa aaacactttg cttatttgac agaagacagc
    73981 cgcgctttgt atagtggaca agacttacat ttttttgaag aatcagaaag atcaggtaaa
    74041 ggtcttagta aacgcaagcc attcagaata accaatattg tgcttccttc gtgtcctaca
    74101 actccaagag gtagatttaa aaattgcagg aagttagaag caatcaacaa gagaataaca
    74161 agaatcgaaa aaataatatt ttgtttgatg atccgccgca tttttaaaga tagccgatga
    74221 ctgtagacaa atttatttaa gtcgcttttc attaagacga tgtctgcgat atccatagcg
    74281 gcatctgtcc cttgccccat agcgacacct aaagaagcgg ctgctaaagc aggcgcatca
    74341 ttgactccat caccaaccat cgcatttact tggtaaagtt cattctcttt tttgactagt
    74401 tgtgtttttt cttccggagt acagcttgca tagtaatgtt caatccctac ttgttcagca
    74461 atggcctttg ctgtgccaga atggtcgccg gttatcatac ttgtatggat gttttgggat
    74521 ttaaagtagg aaattacttg ttgggtattt gcttttggaa tatctagcag acctaaaaca
    74581 gcaattaact gctgatcttt agaaagataa atcacggttt tgccttgatt ttccaaacgt
    74641 tcgatcattt ccgcaatctc tttgctgatt atcatcgtct caggatcata tgcgtgcttg
    74701 ccaactttcc attgcgcacc taaataggta gtttgtaatc caaaaccagt aatttcttct
    74761 attggtaagt attggatttc ttcaggtatt gtgcaatcga aatattgcaa aatcgcatga
    74821 gcaagtggat gcgtcgtttt ttgttccata gcaacaagaa gttgttgtgc caaatccttt
    74881 tcatcaaaga aaaagctgtc agttacaact ggttttcctt tagtgagcgt tcctgtttta
    74941 tcaaaggcaa tcgcttttaa ttcagaaagc ttttctaaat ggataccgcc tttgattaaa
    75001 atcccatttt ttgcagaatt tgaaagagca gctagagaag ctggtgtagc agatgcgaca
    75061 agcgcacaag gagaagccac aactaataat accattcctc gataaaagct ttcatcccaa
    75121 ctccaaccta ggaaaaagtg ggggagaagg atcattagag gaacagcaag caaaatcaat
    75181 tttacataat tattttcgat tcgttcgata aatgaagctg tttgagttgg cgtattctgc
    75241 gcttcttcta ctaattggat aatcttagca aagacagttt cggaactcgt ttttgttact
    75301 cgaatcgtga tgggatttcc ttgattcagc gttcctgcat acatctcatc gcctaaatat
    75361 ttttctacag gcacagattc accgcttaat gcagactcat cgatcgttgc ctgtgtgctt
    75421 tctaaaaagc catctatcgg aacagctgct cctttagcga caaataccaa gttatccacc
    75481 tttagttgag aaacatctac ttcttgcatt tgtccatttt cttttaataa ttgggctttt
    75541 tgtggttgaa gattcatcaa agcagtaatt tctttttgac ttttattagt tgtgtattcc
    75601 tctaatgcac cgcttaaaca aaagatgaat gtcaacattg ctccttcaaa gtaattaccg
    75661 atcaaacagg caccaatagc agctaaagcc atcaataaat ccacattcag tgtccgatca
    75721 ttccacaatt ctttcaagcc ttccgatgtt tgtttatatc caccgatgat aatggcactg
    75781 atataaaaaa gtggggtgat ggtaagagag aatcggtcga agataaaacc gaagatcata
    75841 aataaaaggc agccgattgt tgctgcaaaa gcttttttct gattagtcat cgttattaga
    75901 cctccttgtc aaaacaagga tagcataata aaaatgtaat tgataataat aacagctaaa
    75961 tgagaacgat aatggttatc atttggtgat taagcttgat gttgttttta ttatttataa
    76021 tgattattat taaagaaaat aaaaaaccag aacatttctc aaataaga
//
LOCUS       DACGDM010000006        68686 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.006, whole genome shotgun sequence.
ACCESSION   DACGDM010000006 DACGDM010000000
VERSION     DACGDM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.006"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(592..1983)
                     /locus_tag="IXR05_000447"
     CDS             complement(592..1983)
                     /locus_tag="IXR05_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAQ4258994.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2196..2582)
                     /locus_tag="IXR05_000448"
     CDS             complement(2196..2582)
                     /locus_tag="IXR05_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAQ4258995.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2638..3261)
                     /locus_tag="IXR05_000449"
     CDS             complement(2638..3261)
                     /locus_tag="IXR05_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAQ4258996.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3325..3993)
                     /locus_tag="IXR05_000450"
     CDS             complement(3325..3993)
                     /locus_tag="IXR05_000450"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4258997.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4005..4445)
                     /locus_tag="IXR05_000451"
     CDS             complement(4005..4445)
                     /locus_tag="IXR05_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4258998.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4504..5176)
                     /locus_tag="IXR05_000452"
                     /pseudo
     CDS             complement(4504..5176)
                     /locus_tag="IXR05_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5361..5759)
                     /locus_tag="IXR05_000453"
     CDS             complement(5361..5759)
                     /locus_tag="IXR05_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAQ4258999.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(5756..6529)
                     /locus_tag="IXR05_000454"
     CDS             complement(5756..6529)
                     /locus_tag="IXR05_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4259000.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6526..7209)
                     /locus_tag="IXR05_000455"
     CDS             complement(6526..7209)
                     /locus_tag="IXR05_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4259001.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7376..8263)
                     /locus_tag="IXR05_000456"
     CDS             complement(7376..8263)
                     /locus_tag="IXR05_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4259002.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8260..9129)
                     /locus_tag="IXR05_000457"
     CDS             complement(8260..9129)
                     /locus_tag="IXR05_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4259003.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9266..10552)
                     /locus_tag="IXR05_000458"
     CDS             complement(9266..10552)
                     /locus_tag="IXR05_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4259004.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            10825..11403
                     /locus_tag="IXR05_000459"
     CDS             10825..11403
                     /locus_tag="IXR05_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4259005.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11403..12332
                     /locus_tag="IXR05_000460"
     CDS             11403..12332
                     /locus_tag="IXR05_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4259006.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12329..14065
                     /locus_tag="IXR05_000461"
     CDS             12329..14065
                     /locus_tag="IXR05_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4259007.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14128..14964)
                     /gene="pheA"
                     /locus_tag="IXR05_000462"
     CDS             complement(14128..14964)
                     /gene="pheA"
                     /locus_tag="IXR05_000462"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAQ4259008.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(14961..15470)
                     /locus_tag="IXR05_000463"
     CDS             complement(14961..15470)
                     /locus_tag="IXR05_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAQ4259009.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15463..16758)
                     /gene="aroA"
                     /locus_tag="IXR05_000464"
     CDS             complement(15463..16758)
                     /gene="aroA"
                     /locus_tag="IXR05_000464"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAQ4259010.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(16771..17862)
                     /locus_tag="IXR05_000465"
     CDS             complement(16771..17862)
                     /locus_tag="IXR05_000465"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAQ4259011.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(17879..19045)
                     /gene="aroC"
                     /locus_tag="IXR05_000466"
     CDS             complement(17879..19045)
                     /gene="aroC"
                     /locus_tag="IXR05_000466"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAQ4259012.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19047..20111)
                     /gene="aroB"
                     /locus_tag="IXR05_000467"
     CDS             complement(19047..20111)
                     /gene="aroB"
                     /locus_tag="IXR05_000467"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAQ4259013.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20144..21166)
                     /gene="aroF"
                     /locus_tag="IXR05_000468"
     CDS             complement(20144..21166)
                     /gene="aroF"
                     /locus_tag="IXR05_000468"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAQ4259014.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(21825..22799)
                     /locus_tag="IXR05_000469"
     CDS             complement(21825..22799)
                     /locus_tag="IXR05_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAQ4259015.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(22780..24663)
                     /locus_tag="IXR05_000470"
     CDS             complement(22780..24663)
                     /locus_tag="IXR05_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAQ4259016.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(24681..26906)
                     /locus_tag="IXR05_000471"
     CDS             complement(24681..26906)
                     /locus_tag="IXR05_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4259017.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27021..28055
                     /locus_tag="IXR05_000472"
     CDS             27021..28055
                     /locus_tag="IXR05_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4259018.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28122..29135)
                     /locus_tag="IXR05_000473"
     CDS             complement(28122..29135)
                     /locus_tag="IXR05_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4259019.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29213..29401)
                     /locus_tag="IXR05_000474"
     CDS             complement(29213..29401)
                     /locus_tag="IXR05_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAQ4259020.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(29841..29969)
                     /locus_tag="IXR05_000475"
     CDS             complement(29841..29969)
                     /locus_tag="IXR05_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4259021.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(29972..31345)
                     /gene="rlmD"
                     /locus_tag="IXR05_000476"
     CDS             complement(29972..31345)
                     /gene="rlmD"
                     /locus_tag="IXR05_000476"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4259022.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31456..32511)
                     /locus_tag="IXR05_000477"
     CDS             complement(31456..32511)
                     /locus_tag="IXR05_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4259023.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32521..33951)
                     /gene="gatB"
                     /locus_tag="IXR05_000478"
     CDS             complement(32521..33951)
                     /gene="gatB"
                     /locus_tag="IXR05_000478"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAQ4259024.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(33948..35420)
                     /gene="gatA"
                     /locus_tag="IXR05_000479"
     CDS             complement(33948..35420)
                     /gene="gatA"
                     /locus_tag="IXR05_000479"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAQ4259025.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35420..35725)
                     /gene="gatC"
                     /locus_tag="IXR05_000480"
     CDS             complement(35420..35725)
                     /gene="gatC"
                     /locus_tag="IXR05_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAQ4259026.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(35831..37867)
                     /gene="ligA"
                     /locus_tag="IXR05_000481"
     CDS             complement(35831..37867)
                     /gene="ligA"
                     /locus_tag="IXR05_000481"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAQ4259027.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(37884..40118)
                     /gene="pcrA"
                     /locus_tag="IXR05_000482"
     CDS             complement(37884..40118)
                     /gene="pcrA"
                     /locus_tag="IXR05_000482"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAQ4259028.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40273..41832
                     /locus_tag="IXR05_000483"
     CDS             40273..41832
                     /locus_tag="IXR05_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAQ4259029.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(41943..43874)
                     /locus_tag="IXR05_000484"
     CDS             complement(41943..43874)
                     /locus_tag="IXR05_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4259030.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(43892..44806)
                     /gene="pfkB"
                     /locus_tag="IXR05_000485"
     CDS             complement(43892..44806)
                     /gene="pfkB"
                     /locus_tag="IXR05_000485"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAQ4259031.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(44803..45555)
                     /locus_tag="IXR05_000486"
     CDS             complement(44803..45555)
                     /locus_tag="IXR05_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4259032.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(45714..45923)
                     /locus_tag="IXR05_000487"
     CDS             complement(45714..45923)
                     /locus_tag="IXR05_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259033.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(45934..47262)
                     /locus_tag="IXR05_000488"
     CDS             complement(45934..47262)
                     /locus_tag="IXR05_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259034.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(47627..48214)
                     /locus_tag="IXR05_000489"
     CDS             complement(47627..48214)
                     /locus_tag="IXR05_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAQ4259035.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48297..49547)
                     /gene="clpX"
                     /locus_tag="IXR05_000490"
     CDS             complement(48297..49547)
                     /gene="clpX"
                     /locus_tag="IXR05_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAQ4259036.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVFNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(49794..51083)
                     /locus_tag="IXR05_000491"
     CDS             complement(49794..51083)
                     /locus_tag="IXR05_000491"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAQ4259037.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51237..52169)
                     /locus_tag="IXR05_000492"
     CDS             complement(51237..52169)
                     /locus_tag="IXR05_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259038.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52326..52985)
                     /locus_tag="IXR05_000493"
     CDS             complement(52326..52985)
                     /locus_tag="IXR05_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAQ4259039.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(52988..54013)
                     /gene="sppA"
                     /locus_tag="IXR05_000494"
     CDS             complement(52988..54013)
                     /gene="sppA"
                     /locus_tag="IXR05_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAQ4259040.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54026..54316)
                     /locus_tag="IXR05_000495"
     CDS             complement(54026..54316)
                     /locus_tag="IXR05_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259041.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            54725..56530
                     /gene="glmS"
                     /locus_tag="IXR05_000496"
     CDS             54725..56530
                     /gene="glmS"
                     /locus_tag="IXR05_000496"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAQ4259042.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(56602..57957)
                     /locus_tag="IXR05_000497"
     CDS             complement(56602..57957)
                     /locus_tag="IXR05_000497"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAQ4259043.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(57981..59150)
                     /locus_tag="IXR05_000498"
     CDS             complement(57981..59150)
                     /locus_tag="IXR05_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259044.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59147..60034)
                     /locus_tag="IXR05_000499"
     CDS             complement(59147..60034)
                     /locus_tag="IXR05_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAQ4259045.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60223..63915)
                     /gene="nifJ"
                     /locus_tag="IXR05_000500"
     CDS             complement(60223..63915)
                     /gene="nifJ"
                     /locus_tag="IXR05_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAQ4259046.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64114..64635
                     /locus_tag="IXR05_000501"
     CDS             64114..64635
                     /locus_tag="IXR05_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4259047.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(65334..65891)
                     /locus_tag="IXR05_000502"
     CDS             complement(65334..65891)
                     /locus_tag="IXR05_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259048.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(66070..66681)
                     /locus_tag="IXR05_000503"
     CDS             complement(66070..66681)
                     /locus_tag="IXR05_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259049.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(66794..67051)
                     /locus_tag="IXR05_000504"
     CDS             complement(66794..67051)
                     /locus_tag="IXR05_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259050.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(67648..67926)
                     /locus_tag="IXR05_000505"
     CDS             complement(67648..67926)
                     /locus_tag="IXR05_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259051.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(67960..68211)
                     /locus_tag="IXR05_000506"
     CDS             complement(67960..68211)
                     /locus_tag="IXR05_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259052.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT        19211 a        14833 c        12080 g        22562 t
ORIGIN      
        1 ctgttctaac attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag
       61 ctctcaacag aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt
      121 ttttgttatt tacgctttca cttttcggaa taaataatgt gtatttatat ggaataaata
      181 aaaaaagagg tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca
      241 actcctcggt cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct
      301 ctttgtgact cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag
      361 cttgcatctg cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg
      421 ctgttcttat tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag
      481 aagtagcttc tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa
      541 acttcttctt atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt
      601 cacatcgatc actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc
      661 acttgtcacg ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc
      721 gattaatggt tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc
      781 taaaacgatc agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact
      841 gattgttaca attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc
      901 tgctggtgcg acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc
      961 aatagacaaa ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt
     1021 tgtctgagtc tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa
     1081 gctcaatacc ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa
     1141 aatcagtgag tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt
     1201 acctaaattg acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa
     1261 tactccataa ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag
     1321 actgtcgact aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag
     1381 ataagcgatt ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact
     1441 acctgctaaa tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga
     1501 taagttttca actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc
     1561 tccttgtgtg aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa
     1621 tgctgcaata gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag
     1681 cttttcagaa actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat
     1741 aactagcatt tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga
     1801 ttgagtaacg actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat
     1861 accaactcct aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg
     1921 atagaacaca tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt
     1981 catttttctc ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga
     2041 gaatgattct tcaaccatcc tcctgaaaaa aattttttca gtgactttta tattttagac
     2101 gatttttatc gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg
     2161 atagctttaa tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa
     2221 ttcaatttta ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt
     2281 acgatatcga ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga
     2341 ccttcaattt tccgattgag gatatgattg atctgactca cacttccaga taaaacatat
     2401 gtatcaaaca ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag
     2461 ttttcgatcg tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg
     2521 ttcggcaatc tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc
     2581 atataatttt atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta
     2641 ctttttaatg atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc
     2701 cgggatctca cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt
     2761 ccctgcttcg atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg
     2821 aaaagtatcg atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc
     2881 gatccctact acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt
     2941 tgattctgtc aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc
     3001 cagtacttgt ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg
     3061 gtgaaataat tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt
     3121 agaatacttt ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt
     3181 tagtgcttgc catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa
     3241 gtcccatata taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct
     3301 ctcactttta gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc
     3361 tgctaatgta tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc
     3421 aggaacatct tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag
     3481 taaatcttgc cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg
     3541 attcactgtc atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata
     3601 tctgcggtca aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca
     3661 tgtttttact tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag
     3721 atccccataa tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc
     3781 catttcttct agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac
     3841 ggcatcgaat tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt
     3901 tcctttttct gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc
     3961 gctttcgcca tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg
     4021 aattttatac cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc
     4081 tgcttttgat gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact
     4141 tgctttttgt tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa
     4201 cgttgattct catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat
     4261 ccgaaaaaga cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa
     4321 ctaaagacaa gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt
     4381 ccctgcataa gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc
     4441 atcatattat ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa
     4501 gccttaattg gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc
     4561 aatcacaatc actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg
     4621 aagaaacagc ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat
     4681 caattgagga aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt
     4741 cgttttgatc agattccgtt tttttactga tcacttttaa aaagcttttt agaatctttt
     4801 gctgacgtct aaaaatagaa aaagaatttt cgtcatctat ttgataacgc atttgttttt
     4861 gcagttctgc tgcagtcaga tggatcttcc catcgtttgt atcgatcatt aaaccttctg
     4921 gaaacagttc aaccactgct cgatcccaag attcaagaga aagctcgata taatctttta
     4981 ctggtaattc caattctacc ttaaaaaagt gcaaaacagc cgacagccct tctgcttgat
     5041 agatttctcc taatgttagc ccctctagat ggaactctgg tgaaaaatgc agcaatgttt
     5101 tattttcctg caattgaaca tatagaaatg tagatcgctc aatcagagta tcttttaaaa
     5161 caactaaaaa attcattttt ctcccccttt tttcatcatt tttaaaatag catattttga
     5221 aaagaaagtc tgatgcttag agtagaattt cataaaaatt tactatttca taagtattca
     5281 cgagaaaaat acaaacaaaa aagcggaaat aacgctcatc cgccttcttg tttgtgttta
     5341 tttcctcttc aaacgcttgt ctatgattca gacttttctc tatcgttatt ttcatctaaa
     5401 agttcttgca ttccgataat ttctcgatat tgatgaatct tagtgatacc aatgactttg
     5461 tctacatcaa tactaaaaca aataccatta cctggaatat cgatgttgat gccttgacca
     5521 atcgcatcca ttactttatt cgtcaaacta tcgggtacta atgtcaacac aatatctttt
     5581 tctggcgaaa tgtccaaacc taaaaatttc cctgaatcat gtacaccaga acctcttcca
     5641 tgtaagatcg ttccgcctgc tgcacctgct tcttttgaaa agtcgataac atcttcgccc
     5701 attcctccgt caacgatcgt cacaatcatg tgaagattca atgctacaag atctttcatt
     5761 tgctttcccc caatttttgc aatctttctt tttcgattct gtctttttca tcttttcgtt
     5821 tataaatata tcctagtact aaagtggata atattggtgt caatgcaatc attgcaacca
     5881 caccaaaccc gtcaatgatc ggatctcttc cttcaatttg tgcagcgatt gccacgctca
     5941 ttgataaaat aaatgtcgaa cacatcgggc ccgttgctac tccaccgtta tcaaaagcca
     6001 ttgctaaaaa gatcttgtcc acttttcgtc ctaaaataaa tgctagcccg tatcctggga
     6061 tcaagaaata ataaagagag aatccgacga gcaaacgcca catagacaat cctactgctg
     6121 cgccgatccc aattgaaatt accatcagca tgattttcga tcggattctc ccctcgctca
     6181 attcttcaac ctgtttgatc attacatgaa tcgccggctc agcaaaccct actaagaacc
     6241 ccattaaaaa gccaagggga accagtatat aattgtaagg caatcccgca atagcactgc
     6301 ctaaatgctg tcctaccggt acataagcca tattgactcc gtgcaggaaa aggatcaacc
     6361 caatagtcgt tatcaagaaa cctttcataa tgtcaaagaa acgctttttg cgcatacgaa
     6421 aactaatgat attcattaaa acaaatagga ttacgatagg tgccactgcc aaaatgactt
     6481 ccatggtaac gatttcgatt ccatctatca cttgctgcca gaaactcatt ggaagatcac
     6541 ccccaaaatc atcacggcaa gaatcggccc taacgaagca ataccgacca ttccaaaact
     6601 gtcattttca tttttctttt gtttgatcat actagtcatc cctccggcaa gggccaagat
     6661 aaatggaaca gttactggac cagtagtcac tccccccgaa tcaaaagcaa tcggcataaa
     6721 ttcggaactg gtgaaaaatg aggcgatcaa aacgcctatg tagcctatag ccatcaattg
     6781 ataataggat agcttgaata cgacccgaag cagcgcaaag gctagaaata ctccagtgcc
     6841 gacgctgacg atcccaatca gcaacactct gccaatctct ccgtcagata tatcatatac
     6901 ttgttgtccc aaaacttgca cggaaggttc agcaatcgtg atcacgatcc cgatagcaaa
     6961 tcccaaactg accaaaacgg tcaaactttt ctttttgatc atatatttcc ctactagatc
     7021 tccgacttcc atcatagaat aatctgctcc aaacaaaaag agcgtcattc cgatcatcat
     7081 gattgccgca ccaaccagaa atgaagcgag gtcttctcct tctaacggtg caaaaacaaa
     7141 cgttaaaatg acaatcagga cagtcatcgg caatatagca gcaatcactt ctttaaaatt
     7201 ttttagcatg tatcctcctc ctttactctt taagtttacc ttaaaatgaa agagttttcg
     7261 agcacaaact taaaacgtta tcatttaatt tttctcaaca taaaataaca cacgtcccaa
     7321 aagtatcttt ttacttggaa aaatgacttt gaaggaacgc gcttattgtg tttttttatt
     7381 ttacagagcc gatcattcct tgaacgaatt gcttttgcaa aacaaaaaat acgatggcag
     7441 ttggtaaagt agcgatgact aatccagcca tgatcattcc atagtctggt gtataggaag
     7501 cacccatagc agataaaaca agcggaaccg tccgtttatc aggagattgc aaagctacta
     7561 agggccataa ataattgttc cagctactca tgaatgtgat gattgcagcc gcggcatagg
     7621 tatttttagc cgtcggcata tacactctaa aaaaaatact tagttctttt agaccgtcta
     7681 atcgagcggc ttctactaga tcttttggaa aagatttaac attttgtcga aagaagaaga
     7741 tcaaaaaagc agtgctaaca gatggcagga tgacaaccaa gaaactgttg attcccaaaa
     7801 ccgttccgtt caattgtgaa aacattcgat ataaagggat catcaatgcc gcaaaaggaa
     7861 ccatcatcga tagcagtaga atattgaaaa ttaggtcttt tcgtttactt tgataaatct
     7921 caaatccata tcctgccatt gacgaaatca gcaatgcaaa cacagtggtc accaaagcga
     7981 tcatcgctga attccaaagg gaacgagtaa aattcagctc attggaaaac aaattttgaa
     8041 aattgatgat caagttactg ccaatcttta tttttcccga tgtgatatcc acgggtgtat
     8101 tcgtcattcc caaaaccatc cagacaaaag ggaaaatgga aataaatgat aggatgctta
     8161 atgctgtata ctttaatact gacccaattg tcgaacgaag ttctaatgct tgttttttga
     8221 cgttggggcg ttcgattgtt tctttttcta ccatattttt catcgacttt ctcctcctac
     8281 tttcgtttgg attatcgaca atatcacaat aaaggaaaca ataacaaagg aaactgctgc
     8341 cgcatatcca aaattaggcg tgaatttata actcaaatta tagatgtatt gagatagggt
     8401 ggtcgttgca tttgctggtc ccccgccagt aatattttgt acttcatcaa aaagctgcaa
     8461 tgtcccgatc gtcgaagtaa tggaagtaaa caaaatgatt ggttttaaat ttgggatcgt
     8521 cactttgata aactgctgcc atttagaagc accgtcaata gatgctgctt cataaatctc
     8581 cgaatcaata ttttgcatgc ctgaaaggaa aaaaatcata ttgtatccag tccaacgcca
     8641 agtgatcgaa agaatgatca gaactctcgc ccaaattgga tgagtcaacc agccaatcgg
     8701 tgtgtcaatc ataccaatgc ccaacaacaa gttgtttaca aggccagatt gagaaaatag
     8761 acttttcatg atcagagaat aactgaccat cgaagtgata catggaagaa agatagcggt
     8821 tcgaaacaac cctttatatt tcaacttttt atcatttaaa aggttggaaa taaaaagtgc
     8881 tagaaacaac atgatcggta cttgtacaag taaatacagg aatgtattaa aaaaagcttt
     8941 tttaaaagtt gcatctgtca acatccgctg ataattacct aacccgttaa atgtcatatt
     9001 gacaggggga ccactttgaa aagacgtgat caaagccaaa accatcggaa taaaaaccat
     9061 gattgatatc aaaatgactg gcaagattaa aaaagcatgc ccgtttttga ataaatcttt
     9121 ctgcttcatt cttttccctc caattctatc attgattatc tacatgaaaa gacaagaaag
     9181 acaatatctg taaggcagac gtgatctttt ttgtcttttc gtttgtctga tgaaaaagcg
     9241 aagaaattca cttttttacc accgatcaat tagccaattg tgcttctact tgtttttgtg
     9301 tatctgctag taccttgtct gtctcttctc cattgatgat tcgatgaaga gcttcagcta
     9361 cgactgcttc aattgcatag gtctcatgtc cgtaattcac ttctggtatt tcagatgtcc
     9421 atgttgaaaa atcgtcaaag atcttttgac cactgtaaaa ttcagaagct tcttgataag
     9481 cttcttgttc attcgcgcta agcatcgtag atactagtcc gatttctttc gcaagagtgc
     9541 ccatcagttc ttcattcgaa gcaaacgttg cttctaggaa atctttcgct gaatcttctc
     9601 cagctactcc tttgatcaca taccagccag cgccgccaag gttagaagct tgcgcttttt
     9661 gcagattttc tggaagtgca ggtattggtg caatcttcca ttttccagat tggttttctg
     9721 ctccttggat cgttgaagaa taccaagcgc cagttgggct agaagctact gctcctgatt
     9781 gtatcgcagt tactccagca ttccagtcag aggtttgttc gactagatct tctttcaaaa
     9841 gagtggcaaa caattcaaga ccatacttta aagatgcatt gtcttggatc gtgactgtct
     9901 ccccatcttc agatgtatac cattctcctg cctgttgcat aatcatcctt actcgaccaa
     9961 ggtcagaagg attgacttca gcgattttct ttcccgtctt ttctttgaca tctcgcgcta
    10021 cttgaatata ctcgtcccac ttcagattct ccatatcctc ttctgtataa cctgcttctg
    10081 ccatcagatc cgtacgatag aagtttgctg ttacgcccga atcgaaagga acaccgtata
    10141 ttttatctcc tactttgttt accgcaaatt tatacggtgc aaaatgatct tcctttacaa
    10201 tagcagacaa attagcgaat gcatctggat aagaagtcaa atagccttgt atcctataat
    10261 cttcaatcaa gacgatattg ggcaatcctt ctgtattccc gctcgctaaa gcggtgttca
    10321 gtttctgaac gatatcatcc tgagacatcg taacaacttc tatctctgtt tcttcgttct
    10381 cataaacttt ttttgcttca ttcactgctt tgatattgaa tgtctcatcc cacgcccaga
    10441 cagtgacttt ttcttctttg tctgctgtac tactagcact tccgcatcct gttaagaaac
    10501 ctgatgctgc cgctaaacaa acgactccag caattaactt tctgatgttc atttttatcc
    10561 gctccttttc catccattag ttgtttacgt ttgctacatt catcatacca aaatttgaaa
    10621 acggtttctt tattattcag atacttcaaa aatttctcct aaaataataa aaaaatacaa
    10681 atcaactatg acaaaaggaa taatcttagc atctagacca aagatcgaaa tggtgaggtt
    10741 tctttaaaat aaaaatatcc ttgcattttc tcctagaaat aagtattttt aaattacaag
    10801 actattctta aggcgggtaa aaaaatgcca atacgcgtaa ttcttatcga tgatgaacag
    10861 acgattttag atggaatgaa acagttgatc aattggtctg agcacgggtt tcaattaata
    10921 gggacttttt ccagtccgct gaaagcgctt gatttttctt tggtacatgc aatcgatatc
    10981 gtggtcacag atgtaatgat gcctgaatta aatggaatcg aattatcgcg gctattaaaa
    11041 cagcaacaac ctgaaacaca gatccttatc ctctctagct atgatgaatt tgatatggtt
    11101 aaagattctt ttaaagaagg cgtcgctgat tatcttttaa agcctcgatt gagtcctgat
    11161 ttttttctaa attccttaac tgccgtttca caaaaaatca aaaaaaagcc caacaaaagc
    11221 ccaatcacca atcgttatga gcagatctgc gagaatcttt cacagcagat tgctggacaa
    11281 actcgtccat tgcttgaccc tcttcttttt gaacacacct tgtttttctg ttatataccg
    11341 aaaaacggcc attcagttca aaacaaggct ctaaacaaaa acagtcgatc acccattcat
    11401 tgatggatag cgacgattcg tttactattt atcctgtttc taccttttcg gaagaatccg
    11461 gctatgtaat caatactgat tccaaagata cacttaggaa gtttgttcaa aagtttcgtc
    11521 aagaagtttt tccaggtgat ttttttgttg tttctgattc ttttgcaatc caagatatca
    11581 atgaaatatt ccaagagatc agaaattgca ccaaaggaca acgtttctat cataagggaa
    11641 agaaccttgc ttatcagcat gaacttcttc cgttattaac caaccacgag cagcaagcaa
    11701 gtagttattt aacaaaaatc gttcataaag actacgcttt agctgtcaaa gaacttgaga
    11761 atttcttcac gacgatattg gaacagccta ttgatccagc ttatttgaaa catgaggcaa
    11821 tcaatcgttt ctatgcatta ctcaacgctt tggctgacga gcatgttggg aatgaagaac
    11881 tttctttgct caagatcgcc cttccttctt tattagccga tgctgagtat ttcgaagatt
    11941 tttctattct tgtcaaagaa acacttgaga aactcaccca cttttctgca aatgcaaaaa
    12001 aagacaattt cgatatcttg actttgatct acgagttcgt ccaggaaaat tatgagaaag
    12061 aaatcaattt acaactttta tccgaaaaat atcatttttc atatagctat ctctcagcca
    12121 tctttactga aaaatttggt atcaactttt caaaatatct aaaaaaagtc cgtatcagta
    12181 aagccaagct ctttttgacg gaaacacggc ttactttgac ggaaatctgt gagaaagtcg
    12241 gctataccga actgggttat ttctccagag tttttaaaga agagacagga atgacacctt
    12301 ctcaataccg taaaggaact tttgtaaaat gagaaaaaaa atcaaagagc atgaactctt
    12361 tgccaaactt ctgttcattt tgttcatcgg tctttttctg caagccatcg tcatttcttt
    12421 gtttatttat catcgatcaa gggatgccta tatccagctg ttcaatcaat cgaatgatgt
    12481 ggtactaaaa aagattcaat ctgaatttga aagtttgaat gatacaatcg agaatacatt
    12541 agccgctttt gattctaatc cagctgtcaa aagctatttt tccaatgatc cagcccaaca
    12601 tatggaacag cttcagcaac taagaacaat ccaaaaaatg aatgactctc tttcaaaaat
    12661 ccatccaatg atcgattacg atgtattgat ctttggagaa aatggaagaa cttttgtcgg
    12721 aaacgacatg ctcactgccg tatctgccga ttcttttttt caatctgcga ttgctcagag
    12781 agtgaatgaa cgtgctgctg atacacaaat gctttttgca caccacggat tgactcttcg
    12841 cgataagaaa gcacccagcg tcttctttgt caaaaaactg aaaaatacat tgaatcacgt
    12901 ttacggatat gctgttttat cgatctcatc caagcaacta gcgaatcttt ttcaatctgt
    12961 agtaaatcct gagatatcga agatctcctt catgaacgaa gaacagacga tcatcgcatc
    13021 aaatgaagaa aatacaattg ggagccgatc aatgattttc aaaaaactaa cagtaggtga
    13081 aacaacgatt tcaaatggac agcagttgac ccgtcttcct ctgtaccgcc aggattgtac
    13141 attactcagt caagtcgatc ttcattcttt atctaaccaa atgggcgtga tttttccgat
    13201 tattttgtat aatatcgtga cacttgcttt tgctggctca ttggtattta tgtatttgga
    13261 tcgacacaca aaatcgatct accgcttgat tgattcgcta aaacggctag aggaagatgg
    13321 cttaaaagct actgttcctg tacaaggaag ccatgaagtc caattgctag ggaatacgat
    13381 caatcaattg ctaagtaatg ctcagcatca ttatgaacag acgatccaag acgaaaagaa
    13441 gaaacgttcg cttgaaatcc aaactatgca agcacagata cagccccatt ttatttataa
    13501 tacgctgact agcttgaaat ttttgatttg gcagaaaaaa acagatgaag cagttcaagg
    13561 aatcgacagt ttcattactt tactaagaag tacgattggg aaaaaagaag aagtgattcc
    13621 agtcaaggaa gaaatcaaaa gcgtacaaag ttacatcgat cttttgagta tgcgatatgg
    13681 cgaaagaatc tcggctaaaa taatgattcc tgatgaactg cagtcattat ctatgccgaa
    13741 tatgatcctt caaccaatta tcgaaaacgc ctatcttcat gcttttcaca ataaaacgca
    13801 aggattcatc acggtgtacg gcaaaacaaa aaatcagctt cttttattcg aagtgattga
    13861 taacggcgat ggcttcgata ctgaaaatac caaacaaaaa aatgatcatt tttcaggaat
    13921 cggcatcagc catgtagatg agcggatacg cctaatgtat ggcgatgcat atggcttaac
    13981 gatccaatca gtgattggga caggaacgac tgtaacgatt tgtctaccgc ttcttcctaa
    14041 aaatcaatca gaatatcaaa aataaagaat agccaagcgc tgattttttt attttaagtt
    14101 aaataaatca atcagtattc ttgactttca tctacgcgtc tcttctactg tcagcactgg
    14161 ataacagccc aatatttgac tttctcctcc gagcatcttg atttcttgga gcgcattctc
    14221 tactaatgtc attggacggt ccaacaacaa atcgatcacg aaaaaatatt ctcccaagct
    14281 agttttcaat ggtcgggatt caatcttact taagttgatt tcccgccagc caaaagctgc
    14341 cagcatttta tgaagcatcc ctggccgatt agcaggtagt gtcaagatga cactcatttt
    14401 tactggagct gactgctggc tggtcatctt tcggtcaccg acgatccaaa aacgtgtctg
    14461 gttcaactca ttatcttgga tattctcagc taagatctcc aatccaacat gctgtgctgt
    14521 ttctaatgaa gcaatcgctg ctgcgtcttc tttcggatgt tctgctacat acattgctgc
    14581 agcagttgtt gattctgttg ctactaaagg aacattagga taatgcgttt ctaaaaactg
    14641 ttgtgattgt gctagtgctt gtggatgtga aaggattttt gtaatctttg ttgctggatt
    14701 gcctaaaagc tgctgcttga taggaagaac gatttcactt ttaacttcga cttctggatg
    14761 tttggaaaga agatcgattg tgtgatgaac agctccttcc aatgaattct ctacaggaac
    14821 gacagccaga tcgacttgtt tgcgaaacaa agcgcgcaaa caaacaggga tggaagcata
    14881 cgcagtcaat tgttctgtag gaaatagctg acaagccgcc tgataagtga atgaactttc
    14941 tggccctaga tagctgacgt tcatatgctt ttgatccttt ctataatggt atcgatgatc
    15001 ttttctggtg tttgattggt cgtgttgatt cgatgtgtcg cactttcttc ataccaagaa
    15061 agtcgttgtg ccaataatgc ttttatttct tctcttgttt ttccaagagc taaaggtcga
    15121 atagacgttt catcttgttg gatacgatca actagacagt ccgcttctgc ctctaagtaa
    15181 agaacaatcg gctgtgtttt taaaaaacgc cgattttctg cactttggac aatccctcca
    15241 ccagtcgcga taattttgtc ttcatttgac agctttctta aaatatctga ctccactttt
    15301 cgaaagcttt tttcaccgta atagtgaaaa tattcggcaa tcgacaattg gatatgttcc
    15361 tcaatctttg tatctaaatc tacatactct ttttgtaaac attgagctaa ccctttaccg
    15421 attgttgttt ttccagcgcc catgaaacca atcagcaaaa tgctagccat gagcttctcc
    15481 tcctgacaca agttctgcta aatcgtcaaa aaatgccgga taagagattg aaacagcttc
    15541 agctccttct agttcgcaag gtccatcagc tatcaaagca gctacttgca gcatcatacc
    15601 gattcgatga tcgcctctgc tggacacttt tgcgccatgc agaggtgtcg gcccatggat
    15661 gatcagaccg tctgctgtcg cttttatctt tgctcccatt ttctgtaatt cttctgccac
    15721 cgcatcaatt ctgttggttt cttttacttt taattcttct gcgtctttga tgatcgtgat
    15781 tccttctgct tgagtagcca ctaaagctag aatgggcaat tcatcaatca gacgcggaat
    15841 gatttctcca ccaatcgttg ctttcttcaa atgactcgtc ttgacactta aatcagccga
    15901 ttggttctgt tcattgtgat tcgtctgggt aatcgctgcg cccatctcct ccaacacatc
    15961 taagatacca gttcttgttg gattgacccc gacatttttt aacaacagtt ggctttccgg
    16021 aacaagaagt cctgctgcta gaaagaaagc agctgatgaa atatcacctg gaacagttat
    16081 ctgttgacca gttaattttt gcggtccggt cactatgatc gttttatctt ccactgtgat
    16141 ccttccgcca aattgacgaa tcatttcttc cgtatggtta cgggaacgtt ctttttcaac
    16201 gattacggat gtgccttctg cttgtaatgc cgcaaacagc aaagcagatt tgacttgcgc
    16261 actggctaca ggcatattgt atcggatagg tgataaagag cgggttcctg tcacagtgat
    16321 tggtagatac tggtcatttt cttctccttg caagtcagcg cccatctcgc gtaaaggttc
    16381 catcactcgc cccattggac gtttagacaa cgaagcatcc ccgaacagag tagtcgtaaa
    16441 aggctgtcca gccaaaatac ccatcaataa acgtatggtc gtaccggagt ttcccatgtc
    16501 aattgattcg gttggttgga caaatgagtg gctaccgcga ccatgaatct tgatcacctc
    16561 ttcctcttct tcgatctcga cacctaattg ttggaaggca tgtaaagtac tcagacaatc
    16621 ttctgcgcgc aaaaaatttt gtatagtcgt cgttccttca gcaattgctc caaacatgat
    16681 gctgcgatgg gaaattgatt tatctgctgg tatcctaaca gtccctctta atccatgtat
    16741 ttgttgtaat aattgcattt atccagcctc ctatttgatc cagcaatgat aactggtatt
    16801 agacataatg attctttttg cttgtaacaa atcctgttgg tttttaaaac tgatttgcag
    16861 tattcctaaa atatcttccc tggtctcttg gatcttcaaa ttaatcaaag aaactcccgc
    16921 ttttccgatc agtccagtta cttctgcaat aacgccaggt tcatctggca catcgataaa
    16981 taaatcaaaa aaggcaggaa tcgcgccttg cttatggaca ggcaactggt ctcgactttc
    17041 ttttgcccga ttgaaaaaag aaaagatttc cgattggttc tcagtcatga tccattctgc
    17101 tatttgtgtc atttcttgtt gccaatctgc caatcgttcc aataatatct gcttattgct
    17161 caacaaaata tctgtccaca tgacaggatc tgaggaagcg atcctagtga tatctcgaaa
    17221 gcctcctgct gccagttgtt tggctcgcgg atactcttga ttgaattgtt ctgcctgatt
    17281 gactaagcca gctgccagaa tatgtggaaa atgacttagc attcctgtta tacggtcatg
    17341 ttctcttgct gtaagagtta catattttgc tttggttccg caaaatagtt cttgcagttt
    17401 ttcaacatct tttttcgtct tttccaaagg tgtaaagatg taataggcat tttcaaatag
    17461 tttagcatct gctgcctgta tacctgattt atgagaacca gccattggat gtccaccgac
    17521 aaaccgaaga tttttctgct cagcggatgt cacgacttgc tgcttcgtac tgctgacatc
    17581 cgtaatgatg acgtgatcag acaagttgat tctttcaagg acatcaagat aagctaaggt
    17641 tgtacggacg ggaacggcta ataagataac gtctgcttgt tctgcacctg tttcaaaatc
    17701 acttgcaacg taatcaacga tctgctgttc tactgcttgc tcacgggttt ttgactgact
    17761 atcccaacca actactatca gttctggatt ggtctgacga atacaaagtg ccatagaagc
    17821 accaatcagt ccaagcccca cgataaaaac atgttgtgcc atcttatttg cccccttttt
    17881 agtaatgttt caagtagtca cggtactcct tcactgcagc tttcaactca acaagcgaat
    17941 cacttgggaa ttttgacaat agctctgtcg ctaccacagt ggctacaaca ttttccgcaa
    18001 cgacgctagc tgcaggaact gctgtactat ccgaacgttc tacacttgct ttgtaaggtt
    18061 cttttgtatc gatatcaaca ctttgaagtg gcttgtacaa tgtaggaatg ggtttcatga
    18121 ccccgcgaat gacaagtggt tcgccattgg tcattccgcc ttcgaagccg cctagattat
    18181 tggtacgtcg gaaatagcct ctttcttctt cccataggat ctcatccatc acttctgagc
    18241 ctggtaatga accagaagtg aatccgaccc caaattctac gcctttaaag gcattgatac
    18301 taaccacagc ttgtgcgatt ttggcatcta gcttcgtgtc ccattgtacg tagcttccta
    18361 atccagctgg aacgcctcca acgagcactt ctacaattcc tccgatcgta tctccatttt
    18421 tctttgtctg atcgatcaaa tcttttattc tttgctcaac tgctggatca acaactcgta
    18481 cttctgacgc ttcagaaatt tctttgattt cttgaatcga gatatttcca ggtatttctg
    18541 cttggattcc accaagacaa atcacgtgtc ctgctacgat gatgtcaagt tcttccagaa
    18601 ttttcttggc aattgcgccg attgctacac gcatggtcgt ctctcttgca gaggaccgtt
    18661 caagcacatt ccgaagatct cgatgatggt atttcatacc gcctaccaaa tccgcgtgtc
    18721 ctggacgcgg acgtgcaact cgccgcagtg attggtcttt ttcaggcact tctgctacag
    18781 acatgacagt tgtccaattt ttccaatctt tattttctac cactaaagtg acaggtgaac
    18841 caattgtttt gccgtgacgg atgccagacg tgatccgaac acgatctttt tcgatcttca
    18901 tccttcctcc tctgccgtaa ccagcttgtc tgcgagcgag ttcgtgattg atttcttctt
    18961 ctgacagagg taatcctgct ggtagtcctt caataatggc tgttaattct ggtccatggg
    19021 attctcccgc agtcatataa cgcatcttac agtcctccta agtaatcttt gaatgtctct
    19081 gtgggaacag gaacgatttt tgcttgccca atcttttcta gcaagatgat attcaattgg
    19141 cttcctcttg ctttcttatc atgggttatc gcgtggaata attcatctgg atgacttaga
    19201 tcgtacgtaa tcggcagatg gaatttttga agtatccttt ctaaagcagc tgtcgatcca
    19261 gttggagaca agccgatttt ttctgcatga gaagtgatgg ctaccattcc aatagctact
    19321 ccttctccat gactgactac cccatatcct gctgtatttt caattgcatg gccaattgta
    19381 tgaccaaaat ttaaaataag tcgatttcct tggtcaaaga catcttcttc cactactttt
    19441 cgtttgattt ccaacgtagc agtaatgatt ggaacagcat gttccagaag atctttttcg
    19501 tctttcagct cgttcagctg tttccaaagc gttgcatctg ctatagctgc tgatttgatg
    19561 atttcagcga ttccttctcg taaacgacgt accggcaaag tttttagaac ctcaggatca
    19621 atcaatacac cagctggctg gctaaatgtt ccgacaaggt ttttcgcttt gtttgtattg
    19681 actgctgtct tcccgccaat actagaatct acttgtgcaa gtagcgtagt cggaatttga
    19741 acgaaatgga tcccacgcat gaacgtcgag gccacgaatg ctgctagatc acccaccatt
    19801 cctccaccaa gtgcaagtat cccatcgctg cgggtaaaat cattatctgc taaaaaatcg
    19861 tataactcag ctgcttgttc taaagattta ctggtctcac ccgccggtac gattgaaagg
    19921 actggttcaa aattagcttg tctcaattgg aacatgattt tttctgcata tagtggagca
    19981 acgtttgtat cagtgatcac agctactttt tgaggtctcc aaatcgtttg aagccatgat
    20041 ccagcctgtt ctagtgcgcc tttttcaata tgaatatcgt atttttggtt atcaacatgt
    20101 acagtaagca ttcgtttcac ttctttcttt taaaaagctg gaattaatcg agtgtctgaa
    20161 tcttttccat tgcttctttc atgatcgcaa cttctttcat catgcgtgag taagtctttt
    20221 cattcaacga ttggggaccg tctgaccaag catttgcagg atcaggatgg atctctacga
    20281 tcatgccatc tgctccgctt gccacacccg cacgagccat tggtggtaca agttcccaaa
    20341 ttcctgtacc atgacttgga tcaacaatca cagggaaatg agttaatttt ttcatcaatg
    20401 ggacagcact taaatcaaac gtattacgtg tcgctgtttc gtaagtccga atcccacgtt
    20461 cgataaaaat gacaggagat ttgtcttcga ctgcaatgta ttctgcagca ttaagccatt
    20521 cattgatcgt accggaaatt ccacgtttca atccaacagg tttacctgtt ttaccgacag
    20581 cagatagcag tttaaaattt tgcatattac gtgcgccaat ctgtaggata tcgctgtact
    20641 cagccaccat atcgatatgc ccttcatcca tcacttcagt aatcactttc attccaaatt
    20701 catcagccgc ttgacggatg tatttcaatc cttcttcttc taaaccttgg aaagcatatg
    20761 gagaagtacg tggtttgaag gcaccacctc gcagaatttt tgcgcccccg gctttggcca
    20821 ttcgcgcaca ttctctgatt tggtctaatc cttcgataga acaaggacca gccatcgtca
    20881 cgaaactgcc gtcaccaatt tttactccgt ctacatccac gactgtattg ccaggatgga
    20941 attctcgaga agtcaatttg tatgtgttta aaatacgcac agcattttct actccttcat
    21001 agcgtgtaaa tgctccttct tgtaaacttc gcgtatcacc ttttagtcca atcactactc
    21061 gttctgttcc ttgatcgatt gagactttga atccttcttt ttcgatatga tcgacgactt
    21121 tttttatttg ttcttccgtt gcttcttttt tcataattac tatcattgtt tttcccgctt
    21181 tcttttgttt acttatctat cttggctgat tttctctact ttttcaaggt ggttttacat
    21241 taattcctac taaatgaccg tgtcctgttg ttctcatttt cgctccttct ttcctactta
    21301 tgacccagat aatcaacaaa aaaagatgtc cctgtaggaa attgcctcta cagtgaacat
    21361 cttcaacgag ccttaaaaag cgctgcaaaa atataaaata gccactatag atgaatttct
    21421 ctacgtggct gtaagtcgtg tttaaaaatc tttagccatc atagatacaa acctggtttg
    21481 tttgtaccca cgaagtcatg aatacaaacc tatctaaaat agctaaagta atacgtattc
    21541 agttttgtaa gttttctaga tttcataaaa aatcgctcca aactgatgta agaattgtac
    21601 ctagtataga cataaaaaaa tcgactgtca atcattttta tgaaactttt tttaattttc
    21661 tgatagttaa ctttgttttt cagaaaaata acaattgatt ttattgaaga aaatagtcat
    21721 gaacaaaagt atctgagaac ttttttactc tcttgttcat gacatataga ataaagcagc
    21781 tttgtcttgt aaactccgtt tttcaaataa taatctaaag attgctactg aataataaag
    21841 ccgatttcat ggtcctcttc gctgctgatt cggtaaggtg actcaacatc cgctccccag
    21901 ctattgatac ccccgactcc tcttactttt gcaaaaatcg taagaaccgt tcgtctttct
    21961 ggcggtagtt cttctatatg tgttgcctgt tccagttctt ctgctttgaa tggtaaagcg
    22021 gaaaaagcaa atggcgtatc ctgctgttca aatcgcaacg aaaaatcttc ttgatcttta
    22081 tccgtattat ccaacgtttg atttcttgtt agttctaccc atttcgtttc catatgcatg
    22141 ccgcattctt ggggaacaag gtatggggaa acggggagtc ctgccacttt ataaatacct
    22201 tcgacaccac cagccatccg atccggatat gtttcccctg ataggccttc atactcaaaa
    22261 aattttgctt tcgttggcat aatgaacctt aaacccaatg cgggtaattc cggtaatcct
    22321 ttttgtccat aataatgcat attgacaagc attttaccct ctccagcgat ttggtaggaa
    22381 attgtcactt gggtttttgg tactgtgttg atttccagtg taaaaatgat ttcaaccgtt
    22441 tcagcgtatt cattacttga atattgatta tttactggag caatcggcaa atcgatcttt
    22501 ttattgtcca ccagtacttc tatttctttg acttttggat acaatccggc tcctaaccac
    22561 ataccggatt taaatccaaa tccgctacct ctgtcattat cggtcgttgc tcgccaaaaa
    22621 actggaagtg tttcccggta tagccattct tttccgtttt tattgagcga ttccagtccg
    22681 cctcttgtat aagaaaaaat ataatgcgta ttccccgatt tgacacctaa tgtacagtcg
    22741 ccgaagacga ttgcaacttt ttccgtatcc atatgacttt tatttactgt atttttcata
    22801 ataatatctt acctcctgca tggcgggttt ttcttgtcca tctgcaaaaa cgatcccatt
    22861 ccctgagaat tcatagtcac ttggtttatc gtcaaagtca ccgccatagc gcatcacttc
    22921 tctgcctgtg attggatcag tcacttggat cgcctgatct ttaaaatccc atatatagcc
    22981 tccttggtac atttcataac gatcaagcaa cgtcatgtaa gaatccattc cacctaacga
    23041 attccccatg tcatgcatat attcacataa gatgaacggt ttttccgctt tattttcaag
    23101 gtagtcaatg atctcttctg gtggcgcata catgcagctt tttacatctg aaatcgaatc
    23161 ttcgaatgct ggatttggaa aattcccttc ataatggaca agtcgatcgg ggtctacttt
    23221 tttgaagtaa tcgttcattt gtcgaatgtt ttcttccgca taagattcat ttccaagaga
    23281 ccaaaaaaga atacttggat ggttttttaa tgtttcgaaa ttcgtttttg ctcgatcaag
    23341 aacagccgcc tgccactgag gtactgcacc tggtacgttg taagaaggct caaatgcgcc
    23401 cattttttgc catgagccat gggattcgag gttcgtttcc gccatcacat ggattcctgc
    23461 ttggtcgcat aaataatacc aagtgatctg gttggggtaa tgagatgtcc gtacgccgtt
    23521 gatctttgca ttttttatga tagccaaatc tttttccata tcttctatag tgatggcgcg
    23581 tccttttttc ggatgccact catgtcgatt taccccgttg ataatcatcc gttttccatt
    23641 gaagtagatg attttatctt tgatttcgat tttacgaaaa ccgaaggaat agtcaatata
    23701 ctccgttact cttttttctt cgtctatcgt ctccaattca agcttatata aattgggctg
    23761 aaaatgcccc cacagtgcca cattttcaaa tccatcgatg cgaatcgtca tttgctcttt
    23821 taacggatat tgctgttgat agatttcctt cccatcagga tctagtatcg ctacattcag
    23881 ctgactgttt ttggctactt gctcaaaaga caaatctact tcaagtttgc cattttgaca
    23941 tttgtcatct aagcgaggtt tgatccaaag atcttctaaa tggttttgtc ctcgagcaac
    24001 taagaagaca tctctgaaga tcccaaaaaa tcggaaaaag tcctgatctt ccaagaatgc
    24061 agctgtactt cttttgtaaa cctccacagc tagaatattt tcttcttcca aataaggtgt
    24121 taaatcaaat tcagacggag tgaacgaatc ttcggcatac ccgataaaat gaccattcaa
    24181 ccaaataaac attgcttgtt ctacaccagc aaaatgaatc gagatttgtt ttccctttag
    24241 accttcttct aatcgaaaag tcgtcaaata cgaaccaacc ggattgtctt tagcagctga
    24301 aaagatccct tccgcctctt tctcagggct tgtcgtgaaa gggggacggc gaaatacatg
    24361 tccctcccac ggatacatcg tattgatgta atggatcttg tcataatttg ctaattcaat
    24421 atgactagga acagtgattt catcaaaaga acaggcatca aaatcttttt tataaaatgt
    24481 ttttggtcgt accgaaggat ttggcgaata acaaaaacgc catgatccat ttaaagactg
    24541 tttaagggag gatgtggttt ctacttcttc ccttgttgca taacaaacat gatcgctatg
    24601 tgcatttgat tggttcactc taaaaacttg tggatcatct aaccatttta tatttgcttt
    24661 catacttttt tccttctctc tcataacttt ttgaaatgaa gcagttctgt ttggaaatca
    24721 ccttgaaaat cggggaagta aagtccaact gtcatcaatt cggcccccga aaatatccgc
    24781 ttcgaggtct gttcctgata aagtgcctca tcatctaacc ccatcagata tacttcatgg
    24841 aacgctggtt gagctgaagc tagtatcctc cctaaaaaca caatagcttc atcttgttta
    24901 ggagacacaa acatccatgc ggcaatattt tcttcaaaag gactcgccaa acgataataa
    24961 tggccatact ggatcaccgg acgaatcgtt tgataggata taatttggtc ttttacttgc
    25021 tttttttctt caggagacag ctttgtcaaa tccagttcat aaccaaaaac agcgctcata
    25081 gctgtttctc ctcttgtttt caacgaagta gatctgtcgg tctgatgatt tggtacagct
    25141 gatacatgag ctgtgatgga cgaaatcgga taagcaaggc ttgttccata ttggattttc
    25201 atacgctcca ctgcatccgt gttatcactt gtccatgact gcggcatata ataaataaac
    25261 ccggcatcaa accgtccacc tccaccagaa cagccttccc ataagatttc cggataatca
    25321 gttgtcaaat gttcaagtag ttcataaagc ccgagcatat aacgatgcgc tacttctcct
    25381 tgtctctgtg ggtcaagggt aatcgaatag acatctgaaa gcgaacggtt catatcccat
    25441 ttgatgtagt caagaggaat cgtatctaaa atctttctca tttgtttctc aatcgtctgc
    25501 cgaacatcta accttgtaaa atccagtaca tgttgtgatc tggaagcaga aggcattcta
    25561 cctggctcct gcataagaaa atcaggatgt gttcgataca gttcagaatc aaccgagatc
    25621 atttcaggtt caaaccataa accaaatttc aatcctttgc tatgagcata atctgctatt
    25681 tcacgtaatc catttgtcaa cttgccttca tactcgaacc agtctcctaa tgaagaattg
    25741 tccgcatctc tttttccaaa ccagccatca tctaatacga acatttcgat gcctagctcc
    25801 tttgcttcat caatgatcgc cttgattttt tcactattga agtcaaagta agtggcttcc
    25861 cagttattga ccagaatcgg ccgttcagca aattgatgac gacctcttgc gattctttca
    25921 cgtagcaact catggtggat ctgactcatt ttgttcaatc cctgacttga gtaagaaagg
    25981 atcatttcag gtgtttgaaa agactggcct gcattcaatt cccacgaaaa acgatggctg
    26041 ttgatcccac cgacgactct caattgattg atctgatctt tttcaagttc gaaagaatgg
    26101 ttgccggaat aaacaaattg aagtccgatc gcttctccag tattttctgt cgtatgatga
    26161 tgaactaaag caataaagtt attcatatgg tgactgctcg ttcctcgacg gctttcaaat
    26221 acttttgttc cagataaaac agattgccgt gaaatctgtc tttcattgac atgtgctcct
    26281 ggcaaagcaa tgacttcatc aaatcgccta gtatgggcaa agtctagctg gaaactagcc
    26341 gctttttcta gtttgattgt ttctccggtt tcatttctta tctttacaga tcgtgtgatc
    26401 actgctctat cagtaaatat ggtatagaac aaatcgaaat aaatcgctgt ttctctatcc
    26461 ttaagtgaaa tcaccaacgt ttgtgcctct gacttgtcca tcacataagt ttgaggcaag
    26521 ccttcgatct ctggcttccc atctgtaata taatggctgt catatctcag atccagtaag
    26581 tctgatccat tcttgcgctg aatgatcgat gcgggcgttc gaaagtccat gctgccatga
    26641 gaagagtatt cttgcggtag tgtatctttc gacagagacc ggtcaggatt taagggaaca
    26701 tttcctgaaa atccacgatc tcttcgggga taatttttat tgtctttgta ctgcttgact
    26761 ggtttgccaa aataaatatg cgccaataca ttgctttctt ctatctttat cagataagaa
    26821 agaaatgtat ttcgtaaatg gaagactcgg ctcttttcat caaataagat gaaattttta
    26881 tctgtttttc tatgcgtaat atccatcatt tcactcccaa caaaacggaa accgtttact
    26941 tttttttata attcctgtat actgtttact aaacaatttt gtcaataaaa attttttatt
    27001 tttttgagga gtgtgtaaaa atggttggaa ttagagatgt cgcacgaaag gcaaatgtct
    27061 ctcctgctac agtttcccgt gtgttgaata acgatcagac gatccatgtg gctcagacta
    27121 ctcggcaacg gatagtagag gcagctgctg cgttggatta tgacatcagt actcgtaaat
    27181 atatcaaaaa gagaatgcct tcgattggtg tgatctctac gatcggcaaa gcgagcgaag
    27241 aacaggatat ctattacaaa catttgcgag tagggatgga agaagaagct cgacgtctgc
    27301 atttagggat gaatcgaatc tataatctat ctgataatcc taaacaatgg gaagatctag
    27361 atcagttagg tgcggtgatc gttgttggga ctgttacgaa agaatcgatt accgccttgt
    27421 taaaacaaaa catgcaaata gtcgtcgtgg ataaccctga catccagcaa gaggtcgata
    27481 tggtgtatgc agatcttgaa cggatgacta aaaccgtact ggaattgttc ttagaaaatg
    27541 gtcataaaag aatagcctat atcgggggat ataaagtcga tatggatgaa ttcggtggga
    27601 agcagatttc tataaatgaa aagaggatgc gtgcctatca gcattttatg atcgatcatc
    27661 acttagaaaa atatatgtct tatcatctag gtggctggac agaaaaacaa ggtgaggtac
    27721 ttgcgactaa tctattagaa aatgaatccc ctcttcctac tgccattctt gtcgggagcg
    27781 atccaatggc aattggtgtc tatcgggcat tgaaacaaaa aaatatccaa attggagaag
    27841 agattgttgt agcaagcttt gataatatcg agacaatcgc aaacctctcc cctggcttga
    27901 ccagtgttca aatcaatgcg aaatcaattg ggcaagcagc tgttcgaatg gcattggagc
    27961 gaattgacgg tatacgggac gaaccaatca ttttgactta tcctgcacga ttgattgtta
    28021 gggaaagttt tatcccaaga acaaaaaggt attgaaagag aggttgtgaa aagccgcttc
    28081 gtttcttcat actcaaaacg aaacggcttt ttcacaacct cttacttata cttattcaca
    28141 aaatccaatg tctgctggta acaattttgc gattctttta gcgtgtaatc aaattggtat
    28201 tcatgggtaa tctctttttt tgtatctgta taaaacaagg attgcacggg tacctttaat
    28261 tctgtcaacc gattttctaa tgcttgacct tgctcctgga atgagtatgc atttccgtca
    28321 gttatatacg ttggcggaaa ttccttagaa acatggtcag ccacactagc ttctttcaat
    28381 tgctcactcg ttttccaatc ttttgttcca atcaacgacc acgcaacggt tttgacgaaa
    28441 aacttcataa atcgatcatc cgaatgctgc tgtgctgtta gcttcaaatc aacaggtccg
    28501 caataagaaa tggttccttt cagactatct tttggaagta gctgtttgat tttcatttgt
    28561 ttagcatacg catcattcgt ttgtatagct gcatattgca atgcgatttg tgaacctgca
    28621 ctatctccac caaaaaataa ttgttccatg tctagcaatt tgtcgtcttt ttcttcagct
    28681 aataaatctt tgatcagttc attcacttga agaacttgat tagggtattc tgaatcaggc
    28741 gctaattcat aattcatcgc aaccactgcg atgttggcgt ctgaaactaa ttttgtcgca
    28801 aattctttga cacccgattt atctccgccg acgaatcctc caccatgtac ccaaaataga
    28861 acaggaacag gccccttgct gttttttgga tagtagatgt cataagtatt ctctttatac
    28921 ttggactcat acgtcaaatc tgtttttttc gccacgtttt tttctgcttg atcgaacgtt
    28981 tttttatcag tgatttgaac agtatttgaa aacatatggt tgatcaagaa tgctccaggt
    29041 ctgggggaaa gctggaaggc aagaaagatt gcaaacgcga tcccaagaat gattccgaag
    29101 aaccatccga taaatttaag aattttcttt ttcataaggc tccctcagta gttagtatta
    29161 agcattctga ttataccata gtgttatttc ctatcaagct ctcctagatg atttaatgat
    29221 tttccccaaa cttcttctgc aatgcttttg acaaaagaaa ttttttccat tgttcttcaa
    29281 acaaaacatt ttcttcttct gttgaagcaa atccacattg aggacttaag cacaaacgat
    29341 ccaaaggcag atatcgtgtc gcttcgtaga tccggtcaat cacttgctgg tgctcttcca
    29401 tttcgccatt tttcgttaca gtcaaaatct aagacaacta atttatcttc agagactttc
    29461 tctaaaagaa caaaactccc agcacgttca ctatcgtatt ctaaataata ggcacggaca
    29521 ttttcttgag taaaataatg ggtctgctac gtcgtcatcc cccctgatgc cgccaaaatc
    29581 gaataataat ttccgcgtca aacatgtata tttagtgttg aatcatttga gaatatgaaa
    29641 ataaaaatct ttttgatcaa tcagttaatc aaattgaaat aacgaaaaat ctgagacaga
    29701 atgacgttca ttctgaccca gatttgattt tgcacaactc aacagtcctt attggcaaat
    29761 cgccaaaata atgtagacta actaaaaaga ctaagaaaca ataacaaaag ttaacacttc
    29821 ttagtctttc tttagcacgt ctatttatta aagattttag ggccttttct catgttttta
    29881 cgatcattct taggtgtttc catttgtttg gatcggcctc caccttgttt ctttttgatc
    29941 aattctttca ttttttcttt ttggtccatt tttattctcc tttaacgaat gaagcgacta
    30001 attcgatatg atgggtttgc gggaaaagat ctacaggctg aactttcttc acggcataac
    30061 ctgcttctgc aaataactta gcatctcttg caaaagttgc cggattacat gagatataga
    30121 cgattcgttc tggtgacatt tcgattgctg attcaataaa atgatgatct aatccttttc
    30181 gtggagggtc aactacgatc acagatggtt tgatcccttt ttcttgccat tttttcataa
    30241 ctttttctgc ttttccgact tcataatgaa cattttcgat tttattattt aaagcattga
    30301 actgtgcatc ttcaattgct tctggaataa cttccatccc atacacctta tccactctgt
    30361 ctgctaaaga caagccaatc gtacctattc ctgaataagc gtcgatcaca atgtcttttt
    30421 tatctaactc ggcaaactcg atggctgttt ggtacagata ctctgcttgt tgagtattta
    30481 cttgataaaa tgactttgct gagattcgat aggtttttcc taatagctga tcttcgatat
    30541 agtctctgcc atataaaact ttttctttgt ctcctaaaat cacatttgtt ttttcttcat
    30601 tgatattttg gatgaccgaa accacttctg gcaattcttc atgaatagct tcagcaattt
    30661 ccttggattt aaagaatttt tctttacgag taactaaaac gaccatcatt tcatgggaat
    30721 aatgaccacg acggataatg atgtgacgaa gctgtccttc atttttttct tcattatatc
    30781 ctcgtacttg gaaccgttgc aagatatctc tgactacttt gattgcttga tcgatgacag
    30841 gatcttggat ataaaaatct tcgataggga ctagatcatg gctattcttt ttgtaaaaac
    30901 cggtggctaa ctgtccatcg atacggcgaa cagggatctg tgctttatta cggtagccga
    30961 atggttctgc cattccgacc gttggaagta caggaacttc tggcatctta gcaatcttcg
    31021 ccattacatg ctctacttgt ttttgtttga agacaagctg ttgttcatac ttcaaatggg
    31081 ctaaaggtgc gatacctatg cgaagtaatg cattgttttc tacaggctga cgatcaggtg
    31141 attgtgtaat aaatgtttcg acttttccat atccaaactt attgcctgct tttactacta
    31201 gtatttctac ttcttctcca gggagtgcat tttcgataaa taatggataa ccatcgattt
    31261 ttgctacccc cattccttca taactcaagt cgacgatttc gactgtatat cgttcgtttt
    31321 tctttactat ttgctgttct gtcatatttt gctcctttaa gcctattttt caatcctact
    31381 gaactctact ataaatcagc taattacaca actaaaaccg gcactgacct tactacgttc
    31441 agcaccggct tttgattaat tcttttgatt aggtgtttcg tctgctattt ttccgtcacc
    31501 gtcgatatct tcatccgtta aacgttcgac ttcttttacg aattctttgc tgacaacctc
    31561 taattcttct tcatctgtac ctgtgattgc ttcatcagga atctgatcgg tattggcaaa
    31621 gaactcaatg tgttgatgaa gattttggaa atgcatcggt gcttccccgc cgtattcacc
    31681 atctaagttg atcattactg gtcgattgat atcatcttct gtttcaacga acaaactgct
    31741 tgttttggta tagattattc ttggatcatc gacatgtcga ccgccattca gcatgagtgc
    31801 tgcaatatgc aagatctcaa agatatttgc tgtcttcaca atgattaaag aaaacttccc
    31861 atcatccaat ttggcatctg gcgcgatctg ttcgaatcct ccaacagagt tcgtcagccc
    31921 taggaaaaac atcgaagcat ttccgatata ttccccttca tcatacttca agcgcatttt
    31981 gattggcttt actcgaggga gcatctctgc tcctttcgca agataagcaa gataaccaaa
    32041 aatactcttt agttctgatg gaacttcata agtcaattct gtcaaatagc cacctgcagc
    32101 gatattgatg aagtaactgt tatcagaaag gccgatgtcc atttttacgg tttggtgttt
    32161 ttttatcact tctgctgctg ctttaatatt atctctagga atttttaatg ctcgagcata
    32221 gtcgttcgtt gtaccagctg ggatgatggc cattttagga cggtgttcaa gcggagcgat
    32281 tccattaacc acttcgttga ttgtgccatc gccaccagct gccactacta gatcaaaacc
    32341 tagttctgcg actctacatg cttcattctt ggctgaatct ggttctggtg tagttgcata
    32401 ggcgctggct tcaaatcctg cttcttctaa tgcctgtagg atatccgcca aatttttttt
    32461 caataattct tttcccgagg tggggttata aattacgcgt gcttttttca ttttcagcct
    32521 ctatcgtttc gctaattcat ctttaagtag cttattcacg acaccaggat ttgcttgtcc
    32581 tttagttgct ttcatgattt gaccgactag gaagccaacc gcacgatctt ttccattttt
    32641 gaaatcatcg acagattgtt ggttgttatc caaaatttca ttaatgattg gcagtagttt
    32701 gttcggatca gataattgca cccaaccatt tttttcaact acttcttggg cttctccgcc
    32761 atttgtgatc aattcacgga agactttttt ggcgattttt gagctgatcg ttccatcggc
    32821 gatcaaacga atcattcctg ctaagttctc aggtgtcaat tttgtctcag ctaattccag
    32881 tttctcactg ttcaagtaag cagaaacttc acccatcaac cagttagatg cttgcttggc
    32941 atctgcacca ttttccaaaa cagcttcaaa aaaatcagac atttcttttg taagtgtcaa
    33001 taccattgcg tcatactctg gaagtccaaa ctcacggata tagcgttcgc gacgagaagc
    33061 tggcatctca ggcaaactag cttttacttt ttgaatccat tcgtcatcga tcacgaattt
    33121 cgggatatca ggctctggga agtaacgata atcactagac ccttctttga cacgcatcaa
    33181 aactgtttta ttcgttgttt cgtcaaaacg gcgtgtttct tgttggattt ctcctcctga
    33241 aagaagaact tttgcttgac gtttttcttc aaaagctaaa ccttttttca cgaaagataa
    33301 agagttcaag tttttcaatt ctgctttcgt accgaactct tcttgtccat aagggcgaag
    33361 agaaatattg gcatcacagc gcatagagcc ttcttccatt ttcacatcgc tgacttctgt
    33421 aaattggata attgatcgca atgcttctag ataagcgtat gcttcttctg gtgaacgcat
    33481 atcagcttca gaaacgattt cgatcaaagg cgtgccttgt cggttcaaat caacgtaaga
    33541 ataaccgcca ataccatgca tgttttttcc agcatcttct tctaaatgga cacgttcgat
    33601 ccggattttt ttctttttac cttctacttc gatttcgatc catccgtcat gaccgattgg
    33661 ttgatcaaat tgggaaattt gatatgcttt tggattatct gggtaaaagt aatttttccg
    33721 gtcaaaatga gtatctttag agatttcaca gtttaatgcc aaagctgctt tcatcccgaa
    33781 ttccagcgca gctttattca ttactggcag cacgcctgga taaccccagt cgatcacgtt
    33841 tgtattgctg tttggttctg caccaaaatg agctggcgct ggagagaaaa tttttgagtt
    33901 ggtttttaac tcgacgtgga cttctagtcc aatgactgtt tcaaaattca ttcgtctttc
    33961 cctcctaaaa tagctggttg ttgtttatgg aattctgttg cttgttcaaa cgcatatgcc
    34021 gcttgataca tcgttttttc atcaaaataa ttaccgatga tctgcaatcc aactggtaat
    34081 ccttctgata aacctgccgg tacagacata cctggaagtc cagccaagtt gacagggatc
    34141 gttaagatgt cactcatgta cattgtgatt ggatcgttaa tgttctcacc gattccgaat
    34201 gcaactgttg gtgaagatgg cccgatgatc aagtcataat ctgcaaagac tttttcaaaa
    34261 tctcgtttga tcaatgtacg gacttgtcct gcttttttga agtaagcgtc ataataaccc
    34321 gcgcttaagg agaatgtacc taacatgata cggcgtttta cttcttcacc gaatccttct
    34381 gaacgtgagt tgacatatac atcatctaat gatttcacat tttcagagcg ataaccgtag
    34441 cggataccat cgaatcgttg caaattggaa cttgcttctg atgaggcaat gatataataa
    34501 acagccacac cgtattttga atgaggcaag ctgacttctt ccacaacagc acctaatgaa
    34561 cggaatgttt ctgctgcttt caatacagct tcttttacgc caggggccac accttcgcct
    34621 aagtattctt taggtaaagc aatcttcatt cctttgatgt cgcctgtcag tccctctgca
    34681 aaatcaggaa ctgaaacgcc tgaagaagta ccgtcttttt cgtcataacc gctgatagct
    34741 gtcaatgcta atgcattatc tttcaccgta cgggtcattg gtccgatttg gtcaagagat
    34801 gaagcaaagg caatcaaacc aaaacgtgag acacggccat aagtaggttt catccctacg
    34861 atgccgttaa aagctgctgg ttggcggata cttcccccag tatcactacc taaagaaact
    34921 ggaatttgtc cagctgcaac tgctgctgca gaaccaccag aagagccacc aggtactttt
    34981 gttgggtccc aagcattttt tgttttcttg aaataagaag tttctgtact tccacccata
    35041 gcaaattcat ccatgtttag cttaccaaca gggatcatat ctgcttgata gattttatcc
    35101 atgaccgttg catcataaat tggttcaaaa ttgtaaagga tcttagatgc agcggttgtc
    35161 aagatatctt ttgttacgat attatccttg ataccaattg gaataccagc aaggacgttg
    35221 ctttcatcaa tccctttttc atctaaagct tttgcctgtt ccaatgcttt ttcttcgttc
    35281 aatgtaatga atgcctcgac ctcaggctct gtttctttga ttcgttcaaa tgttgttttt
    35341 gtcaaatctt gtacagtgat ttctttcgat acaagcatat gatgcagttc ttctagagaa
    35401 cgattgtgta attctgtcat tatgcgccag cctccccatt atcgatgatt gcgggtactt
    35461 tgataaagcc gtcttctgtt tccggcacat ttttcaataa ttcatcgcgg ttccatccag
    35521 cttgcgcccg atcttgtcgc atcacgttta ctgtttcaac cacattcgac gtaaatggaa
    35581 caccttccgt atctacttct tccagcattt caaccatatc gatgatttta cctaattggt
    35641 cggtaaaact tgcaagttct tcatctgcga acgcaagttt tgctaatttg gcaacgtgtt
    35701 tcacttgttc ttcactaatc gccatactac cccttctttc taaacgagtt aaaaactttg
    35761 ctctctattt taacacaaga gtgccgtgtc tgaaattgtt tattgaaatt tgtctgaaaa
    35821 aactcatttt tcattcttct actgagcgac ttttagccaa tgcatctgcc atttgatctt
    35881 ctgtccaaac ttcgattcct aattcttgtg ctttggtcag cttgctgcca gcatcttctc
    35941 ctgctaccac gatatccgtt tttttcgata cgctaccagt cactttcccg ccaagatttt
    36001 cgatcgtctc ttttgcttct tcacgagtaa atcgtgttag tttaccagta aggactactg
    36061 ttttttcttt aaaaggagac tcgacttctt gcaattgggc atttcgaagc cctttgtatt
    36121 cgaaattgac gcctgcttgt tttaattcat tcatcaattc atggacttct tcgttactga
    36181 aataagtgac tacactgtcg gcaatgatat caccgatcgt atcaagcgca ataatcgact
    36241 catagtcact tttactcaat gtttctagat caccgaaatg ttctgctaaa atttttgctg
    36301 ctttcgctcc gacatgtcgg attcctaacc cgaaaatcaa ccgctcgacc gaattatctt
    36361 tgctgttgtc gattgctgtc aaaatattat ttgctgattt ttcttttatt ttgtccaacg
    36421 tcaataactc ttcttctgtc aatttgtaaa gatcagcaac atctgctact agttttttat
    36481 catacatctg ttctagtacg cgcggcccca acccatcgat attcatcgca tttcttgaaa
    36541 caaagtggtt caaaccttct ttcatttgag cagggcattt aggattgatg caccgtaagg
    36601 ctacttcttc atccaaatgg acaagttcac ttccacaaac tggacaatgt gtaggcaatt
    36661 ggtattcttc gctgtcttta ggtcgtttat ctaacacgac ttgcgaaact tctgggatga
    36721 tgtctcccgc tttataaatc agaactgtat ctttcaagcg gatatccttc aacttaatat
    36781 aatcaccgtt atgcaggctg gcacggctta ctgtcgttcc tgctactcgg actggtgtca
    36841 tgatagctgt tggcgttact acccctgttc gaccgactgt ccattcgatg ttttcgatta
    36901 gcgtttcaac ttcttctggc ggaaacttgt aagctgctgc ccatctcggt gctttgatag
    36961 taaaaccaag ttgatcttgt agcgagaatt cattcacttt gatgacgatt ccatcgattt
    37021 catagggcaa atccacacgt ttgtcatgat attcttcaat gtatgaccac acttcatcaa
    37081 tcgaatgaca tagacgtttt tcccgattcg tgtggaatcc aattttttct agctcttcta
    37141 gcgcatcata ctgggttttt gcttgcatag gaccgaaatc agctactgtg tataaaaaag
    37201 tgtccagatt tcttttcgct gtgattttag aatctaactg acgcaaagaa ccagctgcgg
    37261 cgttccgagg attcgcaaag atatcttttc cctctgcttc tctgtcttgg ttcaattgga
    37321 caaatgaccg ttttggcatg aaacattcgc ctcttacttc gatgttcatt ggttctttta
    37381 atttgattgg gaccgaccgg acagttttta ggttttcagt gatgttttct cctacagttc
    37441 catccccgcg agtcgcacct ctcacgaaat ttccatcttc ataacgcaaa gaaacggaaa
    37501 gtccatctat ttttagttca cagcaatagt caactacacg tcccactgct ttttgtacac
    37561 gttgatcaaa agctatcagc tcttctttgc tgaaaacgtc gttcaaactg taaagcggaa
    37621 tatcatgagt gactttttca aaaccttcta atacttttcc gcctactcgt tgagtgggag
    37681 aatcagacgt gatcaaatca ggatattgtt cctcgattgc tactaattct gcgtattctt
    37741 tatcataaac atagtcttcc actgttggtt tatcttctac gtagtattcg cgagaccatt
    37801 ggttcagtct tgtacgaagt tcttctgctc gtttagcagc ttcgtcaatc gtcatttcat
    37861 gttccatcat ttaccctcca ctactaagct ttttcaattg gcgcaaaggc agccaaaaga
    37921 cgttttactc cttgacttgg gaaagccaca tctagttcta gatccttcga cgtcccgctt
    37981 actcggacga ctgttcctag accccatttt ttgtgtttga ctttatctcc aggtttccag
    38041 ctgttatttt cccctccagt agcactttta gagggaacaa ccgctgtctc tggctgttta
    38101 tagctatatg ctgttttttt agcgaataca ggcgtttttt taggcgtagg acgcatgcct
    38161 tcgatttcca gtaactcctg atcgatttct tctacaaaac gagaaggtcg gttatattgc
    38221 gtccgtccat ataatgttct ggagaaagca tttgttaaat acaacgcttc ttctgctcgc
    38281 gtgatcccca catatgcgag acggcgttct tcctccagtt cgctttcttc catcaatgct
    38341 cgagataaag gaaaaacccc ctcttctaga ccaatcagga atacaactgg aaattctaat
    38401 cctttggctg catgcaaagt catcaatgtc acttgggaag catcttcttc taaattgtca
    38461 atgtcggaaa caagtgccag atcatttaag aagaccgtta gtttttcttc tggtgcatca
    38521 gcgtcttctt cattttgctg ttcgaattgt ttgtcgaatt cttgtgtgac cgttaaaaat
    38581 tcctccaagt tttcgatgcg tgcttgtgct tctaatgtat tttggatttt taagtcttct
    38641 agatatccgc tacgatccaa aacctctttc gtcaattctg tcactgtcaa gtatgggatc
    38701 atctgagtga cttcttggat catctctcca aatgcaccta attgctgtcc tgcttttcca
    38761 ccgatatttg ccagatccac attttgcgct gcttcaagca gtggccattc atgaagagaa
    38821 gcaaaactgc gtagtttttc gatagatcct ggtccgatgc ctcgtttggg cgaattaacg
    38881 atacgctcaa aactgattga atcttgagga tttaccagca cattcaaata cgctaaaata
    38941 tctttgattt ctttacgatc gtagaacttg tgccctccaa ccattttata aggaatattt
    39001 gctttcaaca gagtttcttc cattacacga gattgtgcgt tcgtccggta caagatggca
    39061 aagtcgccgt aattccgatg attgcttcga atctcttctt gcatccggtc tacgataaaa
    39121 cgggtttcgt ctcgttcatt atctgcacgg tagtaagtga tcttgtttcc ttctttgttt
    39181 tctgtccaca agttttttgg ttttcgattg ctattgtttt caatgacttg gtttgctgcg
    39241 ctaaggatgt ttttcgtgga gcgatagttt tgttctagca aaattactgc agcatctgga
    39301 taatcttttt caaaatccaa gatgttctgc atatctgcac cgcgccagcc gtaaatactt
    39361 tgatctgcat ctcccacgac gcacaggttc ctaaatctac ctgccaataa attgactagc
    39421 gtatactgtg cgtgatttgt atcttggtac tcatctacat gaatataatg gaatttgttt
    39481 tgataatacg tgagtgaatc aggatgttct tcaaataatc gaatcgtatt catgatcagg
    39541 tcgtcaaagt ccatacattg attatattga agctcttttt ggtaagcagc ataacatttt
    39601 gccgcaatct cttcgtaata actgccttgc atttttgcaa aatcctgagg ggtctgcagg
    39661 ctgttttttg cttgagagat tgttcctaat atacttcgag gatcatattt tttcggatca
    39721 atgttcagtt cttttagtat ccgtttcatc aaggtcagct gttcagaaga atcgatgatt
    39781 gtaaagttcc ggttataccc gataaaatca acatctcttc ttaaaatacg cacacacatc
    39841 gagtgaaaag tcgataccca gacatcttcg cctccagatg cgagaatcgc attgacacgt
    39901 tctttcattt cttttgcagc cttattggta aaagtaatcg ctaggatgtt ccaaggattg
    39961 acttcttttt cctcaatcaa ataggcaatg cggtgtgtca gcactctcgt ctttccactt
    40021 cctgcacctg ccattagcag taatggtccg tcagtgtgaa gaacagcttc tttctgacgg
    40081 gggttcatcc cgtttaataa ttcagctttg gatgacatta acaacatcct ttcttttatc
    40141 aatcttgtta attatagcat tttcttggct ttcattaaac tagctagttc aaaatcattt
    40201 gtttcttttt atggattttt ccttgtcaat tcgttgattt cgcgctaaat taaaagaaag
    40261 cgaggcgttt gaatggaaaa aaaaggaaaa atcaagaaat tagataagac tcagatatat
    40321 tttattctaa aaggaatatt tgttggactg ctgacaggaa tcgtcgttag cctgtttcga
    40381 ttatctatcg aaaagctaag cgatttagtt cgaagtatct atgaaatgag tcgggaacag
    40441 ccgatttact taattggcct agctatttgc tgcatccttg cagcattttt cgtgggttat
    40501 ctggtcaaaa atgaaccgga tatcaaggga agcgggattc cacaagtaga gggacagctt
    40561 cgcggggaat tatcaatgaa ctggttctct gttttatgga aaaagttcat tggcggtgta
    40621 ctttcagttg gtgcgggcct ttttctaggt agagaaggac cttctataca gcttggcgca
    40681 tccattggac aaggagctgg acaattgttt cggagtccat cttcagaaga aaagatttta
    40741 atttctagcg gtgcaagtag cggacttgca gcagcattca atgctcctat cgcaggatta
    40801 ctctttgttt tagaagaaat ccatcactcc ttttctccac ttgtttggct gacatcattt
    40861 gcttcagcaa tcactgctaa cttcgtctct ctttactttt tcggcttgag acctgtttta
    40921 tatctaggtg accttccttc tttgccgttg aaatattatg gttccttagt gatcttagga
    40981 gtacttctag gcatcttagg ttttatttat cagaatgtct tgctggcttt gccaaaattt
    41041 tacaaccgat tgcctttacc agcttatttt cacgggttcg ttcctttctt gctgattttg
    41101 ccaattggtt atttatggcc tagtactcta ggcggaggca atcaaatcgt tttagctttt
    41161 ggacatgctt ccttgccaat cattatgatt atcggtttgt ttgttcttcg attcgttttt
    41221 tccatgattt cttacggtgg gggtcttcca ggggggattt tccttccgat attgacattg
    41281 ggggctttaa tcggtagctt ttatggaaac attatggttg atttcgggat ggatccaatc
    41341 tacatcaagg attttgtcgt tattgccatg gctggttatt tcacagcgat tggaaaagca
    41401 ccgctgacag caattatttt agtgacagaa atggttggct ctcttaatca tctgatgcct
    41461 ttaggattgg ctgctcttgt tgcttatatc gtcaatgacc ttctcggcgg taatccaatt
    41521 tacgaatcat tattggaacg tctacttgga aatactcaga ccgcctcact aaaaggtgca
    41581 aggacaactt ttgattttcc agtaacggca gagagttctt tagacggatt aatggtacga
    41641 gacttcaatt ggcctaaaaa tatgctgcta atctctatac gcagaggaaa tcaggaaatc
    41701 ttgactcacg gtgatacgat catgaatgta ggagatattt tggttatctt gactgatgaa
    41761 gcaaacttgc caagaatcaa gcaggaaatc gaggctaaat cttctatcac aaatttgaag
    41821 caatcatttt aacgaacatg gaaaaactat tttacaacaa ctattcatct acactacttg
    41881 attctatatg attctataaa aaaagaagag gctgggaaaa cccagcctct tcttttttat
    41941 ttctatgctt ctgctactgc aggagctttt ctcaataaac cataaatcac accagatacg
    42001 actgctccga tagcaataaa caccaaatac atgaccgggt gactcagtaa gaatacaacg
    42061 aaaatcccgc cgtgaggagc cagtaatttg attccgaaag ctccgactaa tccgccagtt
    42121 aaagcagaac caataataaa acttggaatg gcacgaatcg ggtcagctgc tgcaaatgga
    42181 atcgatcctt ccgtgacaaa cgatagtccc atcacgatgt tcgtcaaacc agcatcttga
    42241 tctgttttgc tgaatttatt cttaaacaaa cgtgtagcaa cgaaaattgc caatggaggt
    42301 accattcctc cagccataac agaagccatc acgacacttc cgccagttgc aacagtcgta
    42361 gctaaagttg ctgtaccaaa cacataagcg gctttgttga ttggaccgcc taaatctgcc
    42421 gccatcattc cagctaataa tgcaccaagt aaagcagcat tcgaaccact catacttgtc
    42481 aagaaaccgt tcaatgcatc attgattgct ttcataggga cattgaccag caacatcaag
    42541 aaaccagtaa tcagtaagcc aaacactgga taaaagagga tcgttttaat tccatccaat
    42601 gattttggta agttcttgaa taatttacgt aaaaatacga tgacataacc agctaagaat
    42661 ccaccaatca gtgcacctaa gaatcctgca ccgcctgtat tagctaatgc accagcagca
    42721 aatccaacga tcaaaccagg gcggtcaccg atacttgaag caataaatcc tgctaatacc
    42781 ggcagcatga aaccaaatgc agcttgtccg atttggttga accagctagc agcttgattg
    42841 taattcccta gatttgataa ttgatcatgt ggcacgccaa taaattggtc gatcatgaaa
    42901 gaaagcgcaa tagcgattcc tccaccaata acgaaaggta acatgtgtga tacgccgttc
    42961 atcaaatctt tgtaaattct ttgtccgata gtaccatccg catttccttc ttctgaactg
    43021 ctttcttttc catcaccatg gaatactggt gcagtaccac taagggctag attgatcaac
    43081 tcttctggtt tacggatacc atcactgaca ggacgattga tcagttcttt tccgtcaaag
    43141 cgattcatct ctactttttt gtctgctgca acgattacac cttctgcacg ggcgatgtct
    43201 tcagcagtca atcggttttt gattccttct gaaccgttcg tttcgacttt gatctccaca
    43261 cccatttctt tcgctttttt cttcaaagca tcttctgcca tgtaagtgtg agcgatccct
    43321 gttggacaag ctgtaacggc aacaacgaat tttctttctg gatgagcaga agcttctgca
    43381 gcttgtgttt cttgttctgc tttttcttct gcttcttttt gctcttcagc tgtttggaac
    43441 aagtcttgga cttcttctgg tgtatttgct tcttttaatt ttcctacgaa atctgcatca
    43501 atcagcaatc gagatagtgc tgctaatgct tgcaaatgtg tgtcgtttgc gccttctgga
    43561 gctgcgatca tgaaaaacag ataagttggc tgtccgtcta aggcttcata atctactcct
    43621 ttttggcttt ttgcgaataa aactgttgct tctttaactg cactgttttt cgcgtgaggc
    43681 atggcgattc catcaccaag acctgtagaa gtttgtgctt cgcgggctag aattccttct
    43741 ttatatgttt cgatatcgga aatccggccg gcatcaaaca ttttttggac catttcatcg
    43801 attgcgcctt ttttatcagt cgcttgcaaa tccatgatca tcgcttcttt gaccattaaa
    43861 tccttgatat tcatgattat cctccttgaa actaatcaat ttttgtgatt tcaacttctg
    43921 gcagcaactc atcaatcaat tcgcgagctg ccaagtcatc agaaaaagct gttgcgcttc
    43981 cgcaagcaac tccccattta aaggcttcga ttggatcttt cgtacggctg taagccccaa
    44041 taaagccagc aatcattgaa tcccctgcac ctactgaatt tttcaatggg cgaactaata
    44101 cattcgtttt ataagttcct tgttccgtga agagcaaagc accgtctcca gccattgaga
    44161 tcagcacatt ctgtgcccct tcagctagta attttttccc atacggaatg atttcttcta
    44221 cagattggaa ggttgtgttg taaagctcag ctaattcgtg attgtttggt ttgatcaaca
    44281 acggtttctt aacaagtgca ttttttaggt catcacctgt tgtatcaatc acgaaatctg
    44341 cacctttttc tcgaatgata tcaatcagtt cttgataaaa tccttttcgc aggctagctg
    44401 gcgcgcttcc tgacaatacg acgatatctc cttgtcctac tgttcctaat gcttgcttca
    44461 actcatcgat ttcttcatct gaaatagatg ggcctaagcc attgatctca gtttcagtgt
    44521 ctgattttag tttgatattg attcttgtat cttcttttac ggttgtgaac aaagactgga
    44581 tttgttcttt ttcaagccac ttcgaaataa attcgccagt gaaccctcct aaaaacccta
    44641 gtgctgtaga ttgagaatcg atccgtttca aaatacggga aacattgatc ccttttcctc
    44701 caggtaactt gaagtcttcc ttcattcggt tcaaatcgcc tagttttaac ccatctacgc
    44761 gtacgatata atcaattgat ggattaagtg ttactgtgta aatcattgta ttgcctcctt
    44821 aattgttgtc ttttcacgga attcattaac gaattctaat ggacaacgct cggttatgat
    44881 cgtggctgct tccaaaggtg caacagaggt gaaggacaac tggttgaatt tggtatgatc
    44941 aatcaataca aatgtctctt cggaattttt catggctaaa cgtttaacag ctgcctcttc
    45001 tggatccgga gtcgtgaatc cttgttcaag atgggcaccg ttcattccca taaatgcttt
    45061 attaaaatga aaatttttta gttgttctat cgcattagat cctaaaacag cattagttgc
    45121 cagctttatc gttccaccta aaataatggt agcaagctcc aaatcaacta aatttgccgc
    45181 atgttgaacg gaatttgtca ctactgtgat ctgttttcct tgcagaaaag gaatcatttc
    45241 taacgtagta gagccagcgt ctaaataaat gacatcttcg tcattaatgg tttcagctgc
    45301 cgatttggcg atttgctgtt tttcgtgaac gtttttgagt gatttttcac tcatattctg
    45361 ctcaaaattc aataattgct ctttcttagc tccgccatga actctttcta gaaacccact
    45421 attctccagc tcttgtaaat cacgtcttat cgttgattca gaagcattca aaaggtttac
    45481 aagatcttgt gatttcacga ttttctgctg ttcaagcaag tctaggattt tttgtctgcg
    45541 ttcctctgta agcattttca cgatcacctc aatacaaata atagcatatt ttttttctac
    45601 tagcaatata aatcagtcaa aaacgttcat aaaaattata aatcagtcaa aaaaaaataa
    45661 aaaaccagtc agaaagactg gttttttatt tttttgtcta tcatcaagcc gttttatcgt
    45721 tttttatttt cgcttcttgt ttttttcata taaacagaag caggttttct ttccttatga
    45781 agaagataat aataaagtcc catcccgcca aacatgacca aaaaaccgat gactgatcga
    45841 ataggaaaat taggaacaaa aaagagacag acggataata atgatgccgg aaccattatt
    45901 cgataataga gttgtttatc cattttcttc acctcatatt ttttgtaaag taatcaattg
    45961 ttctaattct cggtaatcta aaaattgcac acgcagatgc tgctcacctt tcttgacatc
    46021 gaattggata cttcgccgct ttttctttat tcgtttgaag gtaacatcag agagtctatg
    46081 tttgatttcc tttaacggta attctgacag ggattctgaa ggaacataga ttcttaagga
    46141 taaaagatac tcttgatatt tttcatctgt tacctctact tctagatatt ccctaatata
    46201 ataacaataa gcttcgattc cattatccaa agcaacagtc ggatcgataa ctttatagca
    46261 catcatgcgt gatcgattct cgtcaaccca aggaaaatac gcctgagcat ttagtgttcc
    46321 gcgaacacgc ctttctttat aatctccttg ttggatatca taactttttg ttacaaaaaa
    46381 tgaagcattc tttttaggaa caggttgcat ttgtgcattc tgatactgga cagattggat
    46441 cgtatggtca gtgtaaatgt attcaacgaa tggcggtttc aataaaccga caccattgtc
    46501 ccaagcaaga tgatcaaacc caagctggtc cctaaaatag gattgaaaca tttgattgtt
    46561 tggcttttgc cagttaaagg ggtctcgata aagctggata catatgactt cgttttctaa
    46621 ttccttcact ttttctactt gttggatgtc gagaaaaatc ggtttaggga tgatttgatg
    46681 ataatagcga ctataataca tttcccaaca cgaagtgaaa cataaacctt ggtaaaaaag
    46741 atcgtatcct ggaaattggt tgcaatcgac tactacttcc ccgttttgtt gtttcatttt
    46801 aggtaaatgt tcgatttcat cctttttctc aaacaatagc cgttgagaga tctgttttgt
    46861 attgtgatag ataaactcgc tataagctcg catataggcg aacaccccat gagcaatcat
    46921 ttttttctga atgaagtctc gaatcaaaaa ttgcttttct ttgaaaacag agatagacaa
    46981 tacatttttt atcaataatt gattatcttc caagcgaaaa ctacattcgt tctcgtcatt
    47041 tcctacaact aaccaacttt cgtctcttac cgatgctagc attatttttt cttgaagctt
    47101 tcgaagatca tacggatccg cttgttgtgt gaaagagcgg ataaatgttg gctggatcaa
    47161 cagacgtgtc aaaatagccc aatcgcttat ttcctgtttt ttttcttctt catttaagtc
    47221 tgtgagctgg atagtcatca ataatttatc ttcgccaatc attttctcac ctctttcaaa
    47281 tctttttata atttaattat aaccaatgat aaagaaaaac taaaacttta tgtcttagaa
    47341 accaatttgg acgattacat gatagactaa gtaaaaagaa acaaagaggt gtttacaatg
    47401 gggttgaaat ttgaacgtac agataattta gataaacttt tcgaatcatt tgctgtcgat
    47461 ccggaaaaaa cagttgcacc aaaagaagag atcgatcgat ttctaaaacc acagccacaa
    47521 aatgaaaaga aaaaagacaa gaaacaaaag taagttaagc tcaaaaaaag acttaccagc
    47581 caaactttta tgaaagagtt tgactggtaa gtctttttta ttctttttat gattcaattg
    47641 cttgttcgat tgctgcccac gcttcttctt ttccctgttt tgtaacggaa gaaaagagaa
    47701 taaacgtgtc attgcgatca aaatccaacg cttttttgat ttcgctctca tgcttgttcc
    47761 atttaccacg agggatctta tctgccttag tggcaacaac aattacaggg atatcataat
    47821 acttcaaaaa ttgatacatc tggatatctt cttgagaagg cttatgacgc aaatctacta
    47881 aagaaacgac cgcacgtagc tggtctctag tcgttaaata tgtctcgatc atctttcccc
    47941 attttgctcg ctcagttttg gatacttttg catacccata tcccggaaca tcgacaaaat
    48001 gtaatgcgtt ctcgatcaaa taaaaattca atgtctgggt ctttcctggc ttaccggaag
    48061 tacgggctaa attctttcga tcaatcaatg tgttgataaa agaagatttc cctacatttg
    48121 atcgtcctgc cagagctatt tctggcaatt gtgtatctgg atattgtttt ggtgccactg
    48181 cacttatgat aatttcagct tgatggactt tcatggtctc tctccttaac aaggtgatga
    48241 ataaagcaag cggctgtcgc aaaagccaaa atgactttta cggcagcctc ttttcatcaa
    48301 cccgcttttt tctctgaatc tttatagatt actgttggct caccagacaa ttcagctgct
    48361 tcttttgtga taatcacttt ttcgatgttt tcatttgaag ggatatcaaa catcacatcc
    48421 atcatgattt cttcaatgat ggaacgaagt cctcgagcac cggtattgcg ttcgattgct
    48481 tttttcgcaa tggctctcaa cgcttcaggt tcgaattcaa gttcggtatt atctagagaa
    48541 agaagttttt gatattgttt gactagcgca tttttcggct cagtcaagat ccgtaccaga
    48601 tcatctgttg tcaatttctc taaagctgcc ataacaggta atcgtccgat aaactcaggg
    48661 atcaatccga attttagtaa atcttcagga atgatatgct gcatgacact ttcgtcttca
    48721 gaaagttttt ggttttgtgt accaaatcca atcgtctttt cgcccatacg attcttcaca
    48781 atcgtttcga tgccatcaaa tgcaccacct acgatgaaca atatgttcgt cgtatcaatc
    48841 tgaataaatt cttgatgtgg atgtttacgt ccgccctgag gtggcacact tgcaacagtt
    48901 ccttctagaa ttttcagcaa ggcttgttgg acaccttcgc cggaaacgtc acgagtaata
    48961 gatacatttt cgcttttacg cgcaatttta tcgatctcat caatatagat gatccctttt
    49021 tctgcaagtt ccacattgta atcagcagat tgaagcaatt taagcaaaat gttttctaca
    49081 tcttccccca cataaccagc ttctgtcaaa cttgtcgcat ctgcgattgc aaaaggtaca
    49141 ttcaatgttt ttgctaatgt ttgtgctaaa aatgttttac cagaccctgt aggtccgatc
    49201 aagcagatat tgcttttttg cagttcaaca tcatctgtgt tttcttgtgc ttgctgattg
    49261 acacgtttat agtgattgta tacggcaaca gctaacgagc gttttgcgcg atcttgtcca
    49321 atcacgtagt tattaaatac ttcaagaatt tctagtggtt tagggacttc agtgaattcg
    49381 cgtacagctt cttcataaaa ttcttcatca atgatttctt tacataggtc gatacattca
    49441 ttacagatgt agacccctgg accagctacg atctttttca cttcttcttg ggttttcccg
    49501 caaaaagaac agcgtacggt ctcattgcta cttggattgt catacatggt cttcacccct
    49561 taacttgcaa aaagtatgca agaaactatc aaagacttta cagtctttta ctatcataac
    49621 atagtttagt aaaaagaaaa agtgtttaac aaaggatcaa ctgacctata cctttgcatt
    49681 ttttactctt aacaaaaaat aaggaactgt gacaaaatcg tgtcacagtc ccttatttcg
    49741 aataaacaat tttctagaag tagcttcttc agaaatgatt tattacttga tttctattct
    49801 ttcgcttctg tcgctgtacc tgtgatcaat tcgattgctt ttttcattgt cacatcatgt
    49861 tccagcatat cttctgtcaa cacgcgtttg atttgttcga ttggcatgtt gtatgtttct
    49921 gataattctt ggatttctgc attgatttct tcttctgttg cttgaagatt ttcagcagct
    49981 gcaattgctt cgatcacaag atttgttctt gtgcgcattt ctgcttcacc ttcgaattgt
    50041 ttatgcaagt cttcttctgt agaaccagtt aattgatagt acatttcagg agagatacct
    50101 tgacgttgca tgttgttcaa gaattcgtcc attgaacgat gtacttcatc atgaaccatc
    50161 acgtgtggca attcaacgat ttctgcgttt tcaacagcca tacggatcgc tgcttcatct
    50221 tttgcatcgt ccgctgcttt ttcttttgtt tctactaatt ctttgcgata tttttctttc
    50281 aattcgtcta atgttgatac ttcgtcatca acatcttttg cgaattcgtc atctaattca
    50341 ggcacttctt ttgcttttac ttcatggatt gtcactttga agactgcttc ttttccagca
    50401 agatcttctg cttgataatc ttctgggaaa gttacattta catctagact ttcacctgat
    50461 ttatgaccaa ctaattgatc ttcaaaacct ggaatgaatg agcctgaacc taattcaagt
    50521 gagtaatttt cgccttttcc gccatcaaac gcttcgccat ctacaaagcc ttcgaagtcg
    50581 attactactg tatcgccatt ttcagctgca gcatcttctt tgataactaa ttcagcttgt
    50641 gcttcttgtt cacgtttgat acgtgcatcc acgtcagcat ctgttacttc acggtcttgt
    50701 ttttcaacaa ctagatcttt atattgtcct aattttactt ctggtttcac tgttacttca
    50761 gcagtgatta cccagtcttg acctttttcc atgctttcaa catcgatttt tggttgagaa
    50821 acaggatcga tgccagcttc tttgacagca gcttcataag cttctggtaa tacagcattc
    50881 aatgcatctt catataaagc ttcttcaccg tacatacggt tgaatacttg acgagaaact
    50941 ttccctttac ggaatccagg tacgttcaag ctttttttca ctttattaaa cgcagttgtt
    51001 aatccttttt ggatttcgtc ttgcgcaatc gtaaatttta aaacaccatc attcgtgcct
    51061 tttttttcaa atgttgcagt catttaattc cctccgagtt tagaaattca ttttatacat
    51121 caaaaacgtt tcatgcatac ctttaaatag tacactaacc ctttcaaatt gtaaacatat
    51181 tgaatggata gaatccttgt ttttcataac atttttatct ttttcactga taaaatctaa
    51241 tggaagaaga tcatttgctg caaaattttt tctctttttt ttaaaaaatc ttgtttttca
    51301 tcttctgtac cttcatacat cgtttttcct gtacacgcct ctacagtcag ttgaaaccag
    51361 cgcttcgggt cttcgatgta tgtatcatag acaggataaa caattgcaga ttgcaacgtg
    51421 aattcttctt ttaacacgga actaagcagc gcatcttcat tcccgtaacg atctgaaaat
    51481 acacataatt gctggtaact tgcctgctgc tgcggctttg gcagatcttt tggtatgact
    51541 ttgactaact tttcttcaat cgtcaaatag aaaacaggat ggcattcgtt caattgccta
    51601 agtgtctcca gtaattttgc ccttgctaaa atatggacct ctggcgatac aataagttta
    51661 ctcgctgttt ggataaactc atgataagga agctgttcga tctcatcaat agacgcaagc
    51721 tgacgtgcag gttccaacga aggaagttcc tccgatttat tgtggagtgc cttgatcttc
    51781 tgcctctcca tttgtccgga taattcttct gcaaattgga ttttttcaat gacccgctgc
    51841 tcgaaagctt cataaaaatc tgtacttgct atcaattttc tagcatataa aaaatcttgt
    51901 gtactgatta acaagtcaaa ataaaattca gcaaactcct cattttgaag atactgtttt
    51961 tcatgcaaga gtgcttgctt caatgcttct tttttctcgt ccaactcgta aagacaaaaa
    52021 acaagcaggc tattagcctc aaagctttct ttcaactcgt aagctcgttg aaataattct
    52081 tttgcctgct gatattgctg gtttgctagt gcttgttgtg ccactcgcat taaattctca
    52141 tatttttctg gaaaatcaat cggcttcacg cagtgtcctc ctcttgctca tattcagctc
    52201 atgttcaata gtagcaaaac aaaaaaagca tgacaattaa aaataactga agcaccctct
    52261 aaaagctaga ttttagatct gacttttaga aggtgctttc aactgttact gctttttatt
    52321 gctcatcagc tgttgacttc ctggttgaac gctttgatca gattgatcgt aacaacactt
    52381 gtattagtga aaaaatcgcc cagatgttgc tttttctgat taaagactgc tggaagatac
    52441 cctaacatca gcaaaggaaa ttttagaatg aaccggcaag caccttctct aactaaaacg
    52501 gttgaccagc taagttcttc ttcatcaaag ctgatgactc gaataccaaa gatcattttc
    52561 ccaatcgttt ggccatgatt gaatttcgtc aataaaataa aatacgctag ataaataagt
    52621 aaggctgtga atccgtagag actcagataa gaatctgaaa aattaagcca acctagattt
    52681 ttggcaatac caagtgttaa acgcgtaata gctccgatac acaaaagatc gaccaagaag
    52741 gcaaacattc ggataaaaaa acctgcatag aaatacttag gaaaatcatt tgcttttggc
    52801 ggttcatttc ttgtgtccgt atactttttc catttacgtt gtttcttttt gatttcttcg
    52861 ggcgtcaaag gctctctttc aaaagagctc agtacctttt gggaaaagtt ggagtcaggt
    52921 cctacagcag gctgctgttg cttatctttt tcttgttcct tattttcatt tgaaagctct
    52981 gacatgctta ctcacctccg taataataca ttgcttttgg tgattccgct gtccctagat
    53041 tctcaagaac ggataagatc tgactagtct cagaaggctt caatccctgg aattctgcta
    53101 gtttacttcc taaccatgta ctagcaaacc cagatggcgt ggaagaatat tctactagtt
    53161 ccgcatcttc aagctgttgt tcctttcgta tagcttttaa agcatcttca ggaaatccca
    53221 attcatcgac taaacctact tcttttgctt ggacaccatc ataaatcctt ccatcagcaa
    53281 tttttttgac ttcttcttca gatttattcc gtccctcgct gacgattgct acaaaacgac
    53341 tatatgcgct gtcgatatat gcttgaagca ccgcttcttc ttcttttgtc tctggtcgcg
    53401 ttcctgaacc catatctttc aacgctccgc ttttaactgt tgtatcttcc acacccagtt
    53461 tttctagaag tcctgaataa ttcaatcctg acatgatcac accaattgag ccggtcactg
    53521 tttcttctgt tgcaaagatt ttatctgctt gagcagaaat atagtagcca ccgctagctg
    53581 ccatgttttt catgctgaca tacattggga tatcatgttc tttacgaatc gtatccaatt
    53641 tcttagcgat ttccgcactt tcgtagacac cgccaccagg agaatttact tctaaaaaga
    53701 tacctttgac tgttggatct tcttcaatcg ccttcagttg ttccataaaa tttttatgat
    53761 tgtaaccttc agaagcaaat aaacctgaag accctcccgc agcaatcgtt ccatctactg
    53821 ataattttac gattttttgc gtactgtctc cctcttccaa cacatttgga gctagttctt
    53881 catccccata taaccaactg ttcaatccct caatttgatc gttttcctga ggcttagtca
    53941 aactagctga aactaacgaa accacaaata atcctgcagc aatcagaact gctgcccaac
    54001 gtcttttatt cattctttct cctttctaat acaagttttt tatgacgatc acagtttctg
    54061 actgctcaga agtgtcgaac cgctctgctt tttcttcccg cgcatacccg gaaaacgact
    54121 cttttgttaa ttcatcttct accgtaaact cacgagcttg agcaacttcc aaggcatcag
    54181 gtgcgatttc ttggatgcta tcccagccag tatctaaaaa tattttcgta tcatctgata
    54241 caccagctga tgcttcgaat ttggacaatt gtttttttaa cattcccagt gtcatgatct
    54301 caatttttga atccattttt actcctcctc tatccgatta ctttctattg taccgaactc
    54361 ctgaaaaaga tgatagataa aaacccatta ttttttgaca taaaaaggac atttgacaaa
    54421 gaatttgata tataccaatt tattttttat tctttttttg ttgacaagaa cattcgcaaa
    54481 aggttatgat tttaaatgtt tccagataaa aaacaaaaag gaggatagtt atacctttta
    54541 ggatagcgcc aggtctgtgt aaacagatga cgaggagagg gtttatcgaa agattcggcg
    54601 gatggcccta gggactgcac tctacagaaa atccacaaaa aatgtctgca aagataaaac
    54661 aaaaggattt tcctgcagct ggaagcattc atacgaattc attatagaaa gtaggatgtt
    54721 ttttatgtgc ggaattgttg gaatgattgg attaaaaaat gtaacaccag gattgattga
    54781 cggtctagaa aaattagaat accgtggtta tgattcagct ggtatctttg tctcagatgg
    54841 cacaactgat tatctggtca aagcacaagg cagaattcaa aatttgaaaa acaaaataaa
    54901 tattgatact acaggaaata taggtattgg tcatacacga tgggcaactc acgggcaacc
    54961 ttctgaagaa aacgcccatc cacatacttc ccaaagtgga cgcttcgtgc tcgttcacaa
    55021 cggcgtaatc gaaaactttg aagaacttaa aattgcttat ttagcaaatg accactttat
    55081 tggtgagacc gatactgaga ttatcgctca tctaattgaa actttcgcga aggatactac
    55141 aacgcaagag gcgtttttaa aagctttgcg ggtcatcaaa ggttcttacg ctttcgcttt
    55201 gattgatcgg acagcacctg atgttattta cgtcgctaaa aataaaagtc cactattaat
    55261 cggactcggc gatggattca atgtgattgc cagcgatgca atggctatgc ttgctcatac
    55321 gaaggaattc gttgagattg aagatgaaga gatggttacc gtcacatcag aaaaagttat
    55381 tattcaaaat tttgcaggtg acatcgtaga acgttcttca ttcgaagcac aagtagatgc
    55441 ttcagatatc gagaaaggta cctatccttt ttatatgctg aaagaaatcg acgaacagcc
    55501 tattatcatg cgtcgtatcg ctcaaaaata cgtaacagaa gacaatcgtg tctctcttga
    55561 tcaaaagctg gtcgatacat tgtctgatag cgatcgaatc tatatcgttg cttgcggaac
    55621 tagttaccat gcggggttag caggtaaaca gactttggaa aaattgacac agattcctgt
    55681 tgaggttcat ttagccagtg aatttggcta taacacacct cttctttcaa aaaaaccatt
    55741 ctttattttc ttgagtcaaa gtggcgaaac agcagacagc cgccaagtgc tggtaaaaat
    55801 caaccgtctc ggctaccctt cacttacgat tacaaatgtt gctggttcta ctctttcgcg
    55861 ggaagcatcc tttacactgc tattgcatgc tggacccgaa atcgcagtag catcaacgaa
    55921 agcttatact gcacaaatag ctgtactaac tttattagcc aaagctatcg gtgataaaaa
    55981 agaatttgaa acttctcttg tattcgatat cactcatgaa ttgagtttag ttgctaatgc
    56041 gatggaatcg gtcatcgccc aaaaagatta tttagaagag ttggcagaag tatatctcag
    56101 cgatacaaga aatgcctttt acattggacg tggtgctgac tacaacgttt ctcttgaagc
    56161 tgctttgaaa ttgaaagaaa tcagttatat ccaggcagaa ggttttgccg ctggcgaatt
    56221 gaaacatgga acgattgctt tgatcgaaga aggaacacca gtgatcggaa tcatcagtga
    56281 agaagtgact ggtgcgcata ctcgaggaaa cctgaaagaa gtcgaaagcc gtggcgctaa
    56341 aacactagtt attgtctcag agggattaga aaaggaaagt gaccagctgg tgctaccaac
    56401 tgtccaccct tatctaacta ctctaaccac agtcgtaccg actcaattac ttgcatatta
    56461 cgcaacgcta ttacggggat tcgacgttga caaaccacgt aatttagcga aatcagtgac
    56521 agtagaataa taaaagaaca aggaccagtg tcagacatct gacactggtc cttgttcttt
    56581 tattttttat gaaaatatct cttaatccag tccgatttct tctttgacta ctgccgcgat
    56641 tttatcgaca tagtaattaa ctttctcatc agtaggcgct tctgccatca ctcgaagtaa
    56701 tggttctgta ccggaaggac gaactaggat tcttccttct gatcccattt cagcttctgc
    56761 ctcttcaatc acttttttga ttgccggaac atccatcgca ccgtttttat cacttacgcg
    56821 gatattcact aatttttgcg gatagattgt tacctctgct gcaagctctg ataatttctt
    56881 acctgtctgt ttcatgatat tcagtaactg aattcctgaa agcatcccat ctccagttgt
    56941 gttaaaatct aagaaaatca tgtgcccaga ctgctcgccg ccaaagttat aatcgttttt
    57001 gcgcatttct tctacaacgt aacgatcacc aacttgtgta acgacatctt tcaaaccgat
    57061 tccttccacc gctttgtgga atcctaagtt actcatgaca gtcgtaacga tcgtatcttt
    57121 tttcaatcga tttttttctg ccaagtattt agcacagata aacatgattt tatcaccgtc
    57181 gacaatgttt ccaagttcat ccaccgcaat aatacgatcg ccatcgccat cgaaagctag
    57241 tccagcatct gctccttttt caacgaccat ctcagctaaa cgttctggat gggtagagcc
    57301 tacgccgtca ttgatattta acccgtctgg atttgtgccc attgtataaa aatctgtttc
    57361 aagatcggca aacaaacgat taacacttgt tgaagttgct ccgtttgctg catcgacaca
    57421 aatggtcaaa ccggaaaggt caccgttgat cgtttgtaca aggaattgag aatatttcaa
    57481 taagccttct ggaaattctt ctacagttcc caatccttca gctgatggac gaggcaattc
    57541 atccacttca gcatctaata atgcttcaat ttctagctct tggtcatcta ctagtttaaa
    57601 accatctgca ccgaaaaatt tgattccatt atcttgtgct ggattatgag aagcagaaat
    57661 catgacccct gcgcttgctt tttgcaaacg tgtcagataa gcaacacctg gtgtagagat
    57721 cacacctagc tggaacactt cgatacccac cgataaaagt cctgaaatca gcgcttcttc
    57781 taacatttga cctgagattc ttgtatcccg ccctactaac acgcgtgggc gttttccttc
    57841 ttcttcatgc tggcttagga cataacctcc gcaccgtccc agcttaaatg caagttctgg
    57901 cgtaagttcc ttgttggctt caccgcgtac gccgtctgtt ccaaaatatt tacccatagt
    57961 tgtaaaatta ctcctttaac ttaattttct gaggaatttg ttctgctcat ttgtgttgat
    58021 tcgcttgttt ctgatgtttc ttctgtactt gtggtcgagc tgcttgtccc agattccgaa
    58081 ctggaagaaa tggttgttgt cgatggttcc gttcctgaat cagcagatga aatacttcta
    58141 ctcgtacttg tattttcttg tgtccgactg ctcgtcgaag cagagctact gcttgacgtt
    58201 tgcaacacgg gtgtaatctc cacactaact gattcgggct tgatacttaa cccctcttct
    58261 actggtattt caattttacg agttgttcga tgattgatac ctgagacatt gatcggtaca
    58321 gcaatactgt caccgatcga tgcaagcaaa tcgctagagc cgcttacttc tgcttccagt
    58381 tttgaaaaac tgaaatcata gctttctacc ccggcagctg gtgttccttg ctgtatccca
    58441 taaagtcgta ccgacttgct tggcttgatc gaatcagctc tcactgttac ttgcactgga
    58501 tcagagacga tacttaatac ttcccctgct gcattcagcg cctgtattgg gacctcacta
    58561 ttaatcccat catctgtgac catcgaagcg tccacatcag ctactactcg tttgatttct
    58621 gccaatgttt tgtcacctgt agtgatagag acttttttag gactaacgga agtatcatca
    58681 agttcatatc cagatggtgt gaacgttgaa ggaatcaacg tttccacatc gaaatctttt
    58741 attacctttt tctcaaccgt tactgtaata gtcgatggtt cgatctttgc tgtgacagca
    58801 ctgctcaaat tttgaatttt tagcggaact tcatgtgttc cttcgcccag cttagtgata
    58861 tctgctgtga cgcggaacat ccgtgtatct tcgtttgcct ctgcattcaa ctgaactcgg
    58921 tttgcactgg aaagtttgac agtcactgca ttttcatatc catggatata gtagcgcttt
    58981 gaatcataag aaatcttgat cggcaccccc gtaactgttt gattatacgc ttcatttcca
    59041 gaaagcgtat ttggaacgga ctggccattt gcattgaagt acagcgcaat actgaacagc
    59101 aatgcaataa aactgtaaag aatgcttgtc cgtttctctt ttgagatcat ttgcgatccc
    59161 ctcccttagt cataccgtct aggaaagatt gaatcacgtt tttcttgttt tttgttttct
    59221 cttcagcaat tagttctcta cgcaagattg ccaaatattc ttgctgggat aagccagcca
    59281 tcagttcatt atctaacgtg atgctgacgt ccccggtttc ttcagagaca acgatggtaa
    59341 tcgcgtcact gacttcgctt ataccgacag ctgcccggtg tcgagtcccg aattctttag
    59401 ggatcaacat actttctgat agaggaagat aggcgcttgc tactgcgatc tttccttctt
    59461 ttacaataac tgcaccgtca tgcagcggtg tattaggaat aaagatattg atcagcagct
    59521 ccccagtgat atctgcatct aaagcaatcc ctgtctcaat atactcatct aatccagtat
    59581 gacgttcgat agtgatcaac gcaccgattt ttcgcttgga catatattgg atggctttgt
    59641 caaaagacaa gatcatcttc tcatcttcct gctgttcgct ttttgattgt ttgaaaagcg
    59701 aactgcgtcc aagatgttcc agtcctctcc ggatttccgg ctgaaaaatc acgatagcag
    59761 ctatcacccc gtacgtaatg acttggttca tcagccaaga caaggtgtgc agaccaatga
    59821 tttccgctac gattcggata acaataaaaa tagctacacc tttcagaagc tgaatcgctt
    59881 ttgtgcctcg cagcagttgg atcagtttgt atacaagata ccagacaacc agaatatcaa
    59941 gtatgttcac caaaaaattc agagagaaca agtcaccgga aaacatttgc tgccaatagt
    60001 ccaaattaaa aagttccccg atttgaaatg acataaaaag cctctcttct cttttgagat
    60061 ttcctctcta gtatatcata tgttttaatt ttagaggctg atatgctcgt atttttcttg
    60121 agaaaaacgc ataattttca agaaaattgc aagtatgcgt tttatttttc tctgcaataa
    60181 atatttttaa acttcagaga attattcatt atattttttc tgttattttt cctttttttc
    60241 ttttgtagct tgttccattt ttttacgtcg ttctgctctg gcagctcttc tagcagctct
    60301 tctttcttct gcttcaaggt ccgtcgtttt ttcttttcta gtcttaacgg gtacatcgat
    60361 agattcctct ggttcaagtc gtttcttgat tttttctaat tctcccgtca gtgcagcata
    60421 gttgtaaaaa cgtgttttag cgtcgtggac agtcttttca aataaagctt ttgcaagatt
    60481 tggatttgcg ttatctagcg aggaaaagcg aacttgtttc ctcatgaaat caggcatagc
    60541 agagaaatca ggttttttgt agtccaaagt cattgggttc ttgttttttt cgaccattgt
    60601 agggttatat cgatataatg accaataacc agaagaaaca gcttcttttg cttctttaag
    60661 cgattctttc attccgccaa gcaagccatg tgtgatacaa ggcgtatagg caataatcag
    60721 agaaggacca ggatactttt ctgcttcttc aaatgccttg atcgtttgca tttgattggc
    60781 acctgaagca atttgcgcca cataaacatt tccatatgtc atcgccatca ttcctagatc
    60841 tttctttgaa gcatactttc cactagccga aaatttagcg attgccgaag ctggtgttgc
    60901 ttttgaggtt tgaccgccag tattggaata gacttcgtta tccaaaacaa ggatattcac
    60961 gtctgctccg ctggcaagta catgatcgat cccgccaaaa ccaatgtcgt aagcccatcc
    61021 gtctccacca atcatccatt ggctgttttt tacgaataga tcctttctct tgtatatatc
    61081 ctccagttca gggaaaattg atcgttcgct ttcgatcgca gcttgcagtt ttgctgctct
    61141 ttgctgcgtt ccttcactct caaacatgtg tactaaccag tcttccatca attctcgtag
    61201 ttcttctgat acttttggca atacttcttt gattgaactt gccaaagcct cgcgacgagt
    61261 ctgtgccgct agaagcatac cataaccaaa ttcagcatta tcttccaata aagaatttga
    61321 ccatgcaggc ccttgaccac attcattggt cgtataagga gaagcaggag aagcaccgcc
    61381 ccaaatagaa gaacagcctg tcgcattcgc gatcatcatt cgatcaccga acatttgtgt
    61441 caataatttt acataaggtg tttcgccaca gcctgagcaa gcgcccgaga attcaagaag
    61501 cggttgattg aattgtgtag acaagacagt attctttcct ttgactggat ttgctttttg
    61561 tcttaatgtc attgcaaaag cccaattcac agcttgttct ttctgttctt cataaggctt
    61621 catcactaaa gctttttctt ttgcgggaca agcctctaca cacagaccac aacctgtaca
    61681 gtcttccact gaaacttgga tacggtattt tacgccgtct gcgcctcgca tttctctcac
    61741 gataaatcct tctggcgctt cttccatttc ctcttcatct gctaaaaatg gacggatggc
    61801 agcatgagga caaacaaagg cacattcatt acacatcgta cagcgatcac taatccactc
    61861 aggtacttct aaagcgacgc cccgcttttc catagaagcc gttcctaaag gcatttcgcc
    61921 agttgtcatt ccatttgcta caagtgtacc aacagagagt tgatttcctt cctgtgcatt
    61981 cactggttca agtatttctt gtatataacc agtgttcctt ttattgattt tttcaggcat
    62041 ctccaacgtt ctccaatggt ctgggatcgc gacttgatga agcagttcgg tcgtccgatc
    62101 gattgcttgt atgttttttt ctacgatagc cattgattta tgtccatagc ttttcagggc
    62161 ttcttctttt agcagcggaa gcacctcatc aaaaggaatg atgtcagcta atttaaaaaa
    62221 agccgtttcc attgccgtat tgatccggcg tcccaaaccg acttcttggg ccaatctcat
    62281 ggcattgatc gtatagaatc taatgttatt ttcagccaag taacgtttta attttaaggg
    62341 cagatgcgtt tctaattgtt cgtcgctcca aagagtattc aataaaaaaa tgccacctgg
    62401 cttcaatcct ttgaccaagt catagctatg caggtaagct ggtgtgtgac aggcaacaag
    62461 gtccgcatgc tcgacaagat acgctgaacg tatcggcgta tctccaaaac gaagatgaga
    62521 gacagtcaga ccgccagatt ttttcgaatc ataataaaaa tagccttgcg catatttatc
    62581 ggtgtgatct ccaataatct tgatagctga tttatttgct ccaactgttc cgtcagatcc
    62641 aaatccccaa aacttggcct ggaatgtttg cggttctgtc aaatccagac tttcctttgg
    62701 ttccaaagat tgataagtca catcatccac gatccctatg gtaaaccgtt ttttgcgtat
    62761 gcttgggtct tttttcaatt catcaaaaac tgctgagatt tggtcgggag tcacatcttt
    62821 agaccccaat ccgtagcgac caccaataac agccgggcga agttcagaat catataacgc
    62881 actttgaacg tctaataaga gaggttctcc acctgcccct ggttctttac ttcgatcaag
    62941 aacagcaatt gtttttactg tatgaggcaa cttttgcacg aatgtttcca ctggaaaagg
    63001 acgataaaga tggatattca aaaaacctgt tttccgtccg tttgcattca agtaatcaat
    63061 cgtttgttca atcgtctgtg caactgatcc catagaaaca atgacttctt ccgcatcgtc
    63121 tgctccgtaa taagtcacca agtcataaga agttcctcgt aatcggttga tctctttcat
    63181 atatttttga acgatttcag gtaatttatc ataatagggg ttgatcgttt cccgttgttg
    63241 aaaatggatg tctggattct ggttcgtacc actaacagtc ggatgattgg gattcatccc
    63301 tcgtttacga aatgaagcta atttctcctg attgatcaga ggagctaatt cttcatattc
    63361 caaaacttcg attttttgaa tctcgtgact cgtacggaat ccatcaaaga aattcaaaaa
    63421 agggacttct ccttcaatag aagcaagatg ggcaacaggt gctaaatcca tcacttcttg
    63481 tacactgctt tcagctaaca tagcaaatcc tgtttgtctt gcagccatca cgtctccgtg
    63541 atctccgaaa atattcaacg catttgtcgt cactgcccga ctagcaacgt ggaaaacact
    63601 tggcagtagt tccccagcaa tcttgtacat attcggtatc atcaaaagca gcccttgtga
    63661 agcggtatat gtagttgtca gtgcaccagt tttcaatgat ccatggacca caccagctgc
    63721 tcctgcttcg gattgcattt ctactacttt tactggttga ccgaatacgt tttcttttcc
    63781 tgctgctgac cattgatcta ctaattcagc catggtcgaa ctgggtgtta ttggatatat
    63841 tgcagcaatc tcggtaaatg cataagaaat atatgcggct gccgtattgc catccattgt
    63901 tttcattttt cgcatgattc atcatccttg ttcatattct ctcttattat ctgttccatt
    63961 ataacgtaaa acatgccatt tttttctttt atttataaaa atattttaca tgtatctatt
    64021 tgaattggtc atctaatttt tagacaaaca gtctaaatcg ttgccttttt ttgtcagaca
    64081 tgtataaact ataagcgaaa gaggtgtttt aacatggata tatcagtgat tgatgcaacg
    64141 aaaacaaata cacaaaaagg aatcctttat ggttcatcga atgctcctaa aaaaatggtc
    64201 gaattcatca acttagcttg tccgtattgc cgacaatggt ttgaagaatc ttatgagcta
    64261 ttagaagaag cagtccaaag cgggcaattg cagcgagtga tcaaattgtt cgataaagaa
    64321 aaagaaagct tacagcgagg gaacgtgatg caccggtatc tcacaatcag cgatggccaa
    64381 aaagcgatca aagagatcaa acaaatattc gatactcaag acgagtggaa acatctttct
    64441 ctccaagaag tagcggattt tgcagtagat aaactaaagc tgacagaaca aaaagacgaa
    64501 cagctgagcc aagctgtcat caacgaagct gagcaagcac atattcgatt tgttccaact
    64561 gtcatcttgg gtaaagaaat ctttgatgaa tctatttcaa tagaggaatt aaaagaattg
    64621 atccaaacaa aataaaaaaa taaggagcgt gggacaaaag taaagaacac ttttgtctca
    64681 cgctctaaac acgtataaac ggcggaagca gaagcaactc cttcttattt cttggagtta
    64741 aacgcttctg tcccagcctc cttattccga ataaatggtg tccaaaagct tgcatctgcc
    64801 agattatctc atttcttatg acaagctaag caaattatct ccaccaaata atttattcat
    64861 atttttgact tgcgcatact aactaattct taaattttca tacaaaattt ctcaatttcc
    64921 cttaacgagt aatatttatg tacggtgatt ctcactagta tcccaatcac tttttaagtt
    64981 atcccgattt caattctact tcaaaaatag ttgcttttat gtatgctgtt agttgattag
    65041 atggtcattt gttgagctag gtcgtttatt ttaaacaagt tgtttcttta gcttatacct
    65101 atctcgtcta ccaaacgcaa gatggcaaac acaaatgcat acgcatctgt atttgccact
    65161 ttgattcgta taaagctaac aactattaac tcctctcagc taatagttgc tctctttttt
    65221 attcagattc atttttgctg atcacagcct agtatttcaa tggttttgaa cactaaacca
    65281 aattgttcca ttacaacatt cactggctga tgaaatggat tagtagattt cgattattca
    65341 aagcgatttt ctattggtgg atcgtgttcc caactaataa gacggattcc aaacctatcg
    65401 tacagatctt ctaaaccact tataaatttt gcacctattt caggtgtttt attgcgtgga
    65461 tattctattg ttacgccatt aaatggatac caattaggat taggctctct ttttttctgt
    65521 acatctccca tagaatagtt agcactttct gggacataat atattcttcg accatcctct
    65581 aattcatcta ataagatatt tcgtgatcgt ctatcacttg ctaaatgtag acgccacgtg
    65641 cgataccatg ccatgctacc tgcatctgca gaaaatccat caaataatgc aacaattgta
    65701 tcttctatca caatcctttc cccatctact tcatattcta atctaaaatc aaactcccct
    65761 cgggtaattt ctggtcttgg tggcttagga cccaatatta ttctacttaa aaccgcattc
    65821 gttcccagat gaaacacagc tataacaaca ataatgatta atattttgtt tctatttgat
    65881 aaatttctca ttattcgcac atcacctcta cattctcaca tattagttcg taatactcct
    65941 ttaatatcaa aatatctact ggtcgtaata atattcgcta tgaattccta ctactcgtat
    66001 aagaaaggcc aaatcatcag cttttacttg ctgatgattt ggcttgtttc tatttatcgt
    66061 aattgttttc taatcaccaa aattgttaac aatcggttca gatatttccc agttgattaa
    66121 ggtaattccg tattgtgtca aaacttcttg cgcttctccg aaattaagta cagttcttat
    66181 gtatccactt tctcctaata taaagtctac ctctctttta aaaccttcct cgagatttct
    66241 aagggctata tgtggtttta atgacattga ttgtacattt tcccccatat aatattgcgc
    66301 acttcctcga ctaaaataga ttcctagatc gtccccaaaa ggtagatctt ctctaccact
    66361 agctaatcta cttctccatc ttcgttctct tttcatagaa cctgcgctga actcacaccc
    66421 gttaaactca gctatgacag tatcttcaat tatgttaatc tgtccatcta gttcgtattc
    66481 aatcctaaat ggaaattctc cataggtgat ttccggttcg ggtattttag gtgagattaa
    66541 tgcaaagaaa ggaaatatta agcttggcaa catcaaaaaa actcctccta tgatcacaat
    66601 tcccgatgta atccaaaata taatttgtac aattctcatt gatccattgt attccatttt
    66661 attcccccta ttactattca tatccgccta tctatatcga tcttccaatg cagagataat
    66721 tgcttccata ccttgatttt ttactgagtt acctatgcga gatatcattc tccactaagg
    66781 tgcatcatat tgtctatcta acatgattaa ttctccaata ggtgtatact cctccaaaaa
    66841 caacatttaa tgcatctccc tcgacaacat aagctaccat gtttgctgta tatgtgtttg
    66901 agtctaattc ataagcagat aaatttactg tcgctggatt aaatataatc gcattcgtat
    66961 ttatagctac tgaatttgct gcttcagcac caccttttga atgtccgatc attgtgattt
    67021 caatagtagg atttacgtgg acagccctca ccgtttaccc tgaccattat agaaatcgct
    67081 tacttttttg aactacgcaa caaaggatac aatgctccta acttcactgt ctccattttt
    67141 gtccactaag gaatataaaa aataggcatt aattcattta attcggtcac aacacgttac
    67201 cttttaaatc attatactgt atctcataca ttattatcaa taaactatta taaaaatgca
    67261 aaaaatgctt tatcaatcta ttttgtaatt ggtcataata tcattgaaat cataccctgt
    67321 atcgattttt cctatgaatc tcgtctattt gtgattgacg aaaaagaggc aagacagaca
    67381 ctggaatggt aattttaccc actattttgc tccaactatt tgtaatcgta cccacttttg
    67441 aaataccgag atgatcattt taattgatat gctgattccc aagcaaaacc ccaagaaatt
    67501 aaatgctcta tcgcatctag cttcttgggt tttgcttata taaattccaa catttaaatt
    67561 ttttatgctg ttcggtctca gaaatgccgt ttttgcttat atcacaatat caagatgtca
    67621 aattattcgt gttgccgatg actttgatta atttttttca aattgtttat taagactaat
    67681 gctgtctttt tgcagatacc aatgttcgaa ctttttaaca ttatcatatg atcctgcaag
    67741 ttttaacttc ttaccattag atgttatcaa agttataatt aaccttgcct ttttcccatt
    67801 aggatctttt attttatgaa ttttctgcag gtaatctctc ctaatggcag ctatttttac
    67861 ctcatcagtg ctgataaacc attgatcatc cacatacata ctgcctgtta tgttgtgttt
    67921 ttccatttct tccgagaacg aaaagtttaa ggctcgttct tacttccaaa gttgaatgag
    67981 tccatggatt ggacttagtg tgagaattga gaacaacaat aagaatccat atcctcccgc
    68041 aaacatccct aaggctatac tgtctctcca tccataagta ggattagaag agaaaagagt
    68101 caccgtttgt aataatatga aaaggaataa tccagcacaa acaccaaaga taacaactcc
    68161 aaacattgaa tttttataca atgaccattt atttataggc ttttctttca ttttacttcc
    68221 ccctactgtt ctgttcacac ggaatgaatt caaagttcat aagccctcct ctttgaacat
    68281 atgaatacga cttgctaact atactttaaa aaagcttgtt ttaagcggtt ataggcgagt
    68341 tgtaatctct attcatctca ttagcaaata acttgccgaa aagtctactg aaattaaagc
    68401 agatagtgga agaattattt agccaggata gacactattt gtgaaacaca tgtctttact
    68461 tttgaaattc tatgatgaaa agccttggaa tacagtagct cttaattggt aatacttttt
    68521 ccattataaa taacctcttt tcattttata tttatcccct ctaaaaataa tatctaatct
    68581 aatattttaa acttatattt ccctcgctgt gctaatagag cattactaaa taaatagaaa
    68641 ctagaaaaaa gcattacgcc tgccagaata aaccaattat ttgtat
//
LOCUS       DACGDM010000007        61342 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.007, whole genome shotgun sequence.
ACCESSION   DACGDM010000007 DACGDM010000000
VERSION     DACGDM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.007"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..563)
                     /locus_tag="IXR05_000507"
     CDS             complement(<1..563)
                     /locus_tag="IXR05_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HAQ4259053.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="IXR05_000508"
     CDS             complement(750..1400)
                     /locus_tag="IXR05_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259054.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="IXR05_000509"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="IXR05_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAQ4259055.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /locus_tag="IXR05_000510"
     CDS             complement(2912..3910)
                     /locus_tag="IXR05_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAQ4259056.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="IXR05_000511"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="IXR05_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAQ4259057.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4926..5657)
                     /locus_tag="IXR05_000512"
     CDS             complement(4926..5657)
                     /locus_tag="IXR05_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAQ4259058.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5661..6926)
                     /locus_tag="IXR05_000513"
     CDS             complement(5661..6926)
                     /locus_tag="IXR05_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAQ4259059.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="IXR05_000514"
     CDS             complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="IXR05_000514"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAQ4259060.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="IXR05_000515"
     CDS             complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="IXR05_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAQ4259061.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12268..13770
                     /locus_tag="IXR05_000516"
     CDS             12268..13770
                     /locus_tag="IXR05_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4259062.1"
                     /translation="MKRKHLFHSFVFLMTGLVTFAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13772..14509
                     /locus_tag="IXR05_000517"
     CDS             13772..14509
                     /locus_tag="IXR05_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259063.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(14554..14727)
                     /locus_tag="IXR05_000518"
     CDS             complement(14554..14727)
                     /locus_tag="IXR05_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4259064.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            14703..15368
                     /locus_tag="IXR05_000519"
     CDS             14703..15368
                     /locus_tag="IXR05_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAQ4259065.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(15450..16616)
                     /gene="dnaJ"
                     /locus_tag="IXR05_000520"
     CDS             complement(15450..16616)
                     /gene="dnaJ"
                     /locus_tag="IXR05_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAQ4259066.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(16767..18596)
                     /gene="dnaK"
                     /locus_tag="IXR05_000521"
     CDS             complement(16767..18596)
                     /gene="dnaK"
                     /locus_tag="IXR05_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAQ4259067.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(18647..19210)
                     /gene="grpE"
                     /locus_tag="IXR05_000522"
     CDS             complement(18647..19210)
                     /gene="grpE"
                     /locus_tag="IXR05_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAQ4259068.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(19304..20347)
                     /gene="hrcA"
                     /locus_tag="IXR05_000523"
     CDS             complement(19304..20347)
                     /gene="hrcA"
                     /locus_tag="IXR05_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAQ4259069.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(20581..21747)
                     /locus_tag="IXR05_000524"
     CDS             complement(20581..21747)
                     /locus_tag="IXR05_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAQ4259070.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(21763..21990)
                     /locus_tag="IXR05_000525"
     CDS             complement(21763..21990)
                     /locus_tag="IXR05_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAQ4259071.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            22474..23064
                     /locus_tag="IXR05_000526"
     CDS             22474..23064
                     /locus_tag="IXR05_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAQ4259072.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            23254..23967
                     /locus_tag="IXR05_000527"
     CDS             23254..23967
                     /locus_tag="IXR05_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259073.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(24082..25092)
                     /locus_tag="IXR05_000528"
     CDS             complement(24082..25092)
                     /locus_tag="IXR05_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAQ4259074.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(25129..25611)
                     /locus_tag="IXR05_000529"
     CDS             complement(25129..25611)
                     /locus_tag="IXR05_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAQ4259075.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            25761..26129
                     /locus_tag="IXR05_000530"
     CDS             25761..26129
                     /locus_tag="IXR05_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAQ4259076.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            26594..27046
                     /locus_tag="IXR05_000531"
     CDS             26594..27046
                     /locus_tag="IXR05_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4259077.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(27170..28021)
                     /locus_tag="IXR05_000532"
     CDS             complement(27170..28021)
                     /locus_tag="IXR05_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAQ4259078.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(28034..28819)
                     /locus_tag="IXR05_000533"
     CDS             complement(28034..28819)
                     /locus_tag="IXR05_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4259079.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(29171..30112)
                     /gene="ribF"
                     /locus_tag="IXR05_000534"
     CDS             complement(29171..30112)
                     /gene="ribF"
                     /locus_tag="IXR05_000534"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAQ4259080.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(30116..31039)
                     /gene="truB"
                     /locus_tag="IXR05_000535"
     CDS             complement(30116..31039)
                     /gene="truB"
                     /locus_tag="IXR05_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAQ4259081.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(31407..33769)
                     /locus_tag="IXR05_000536"
                     /pseudo
     CDS             complement(31407..33769)
                     /locus_tag="IXR05_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            34217..34390
                     /locus_tag="IXR05_000537"
     CDS             34217..34390
                     /locus_tag="IXR05_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4259082.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(34547..34894)
                     /gene="rbfA"
                     /locus_tag="IXR05_000538"
     CDS             complement(34547..34894)
                     /gene="rbfA"
                     /locus_tag="IXR05_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAQ4259083.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(34921..37227)
                     /gene="infB"
                     /locus_tag="IXR05_000539"
     CDS             complement(34921..37227)
                     /gene="infB"
                     /locus_tag="IXR05_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAQ4259084.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(37240..37551)
                     /locus_tag="IXR05_000540"
     CDS             complement(37240..37551)
                     /locus_tag="IXR05_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAQ4259085.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(37548..37841)
                     /locus_tag="IXR05_000541"
     CDS             complement(37548..37841)
                     /locus_tag="IXR05_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAQ4259086.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(37863..39038)
                     /gene="nusA"
                     /locus_tag="IXR05_000542"
     CDS             complement(37863..39038)
                     /gene="nusA"
                     /locus_tag="IXR05_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAQ4259087.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(39061..39534)
                     /gene="rimP"
                     /locus_tag="IXR05_000543"
     CDS             complement(39061..39534)
                     /gene="rimP"
                     /locus_tag="IXR05_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAQ4259088.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(39679..44037)
                     /locus_tag="IXR05_000544"
     CDS             complement(39679..44037)
                     /locus_tag="IXR05_000544"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAQ4259089.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(44249..45958)
                     /locus_tag="IXR05_000545"
     CDS             complement(44249..45958)
                     /locus_tag="IXR05_000545"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAQ4259090.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(46026..47294)
                     /gene="rseP"
                     /locus_tag="IXR05_000546"
     CDS             complement(46026..47294)
                     /gene="rseP"
                     /locus_tag="IXR05_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAQ4259091.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(47455..48255)
                     /locus_tag="IXR05_000547"
     CDS             complement(47455..48255)
                     /locus_tag="IXR05_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAQ4259092.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(48252..49064)
                     /locus_tag="IXR05_000548"
     CDS             complement(48252..49064)
                     /locus_tag="IXR05_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAQ4259093.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(49259..49816)
                     /gene="frr"
                     /locus_tag="IXR05_000549"
     CDS             complement(49259..49816)
                     /gene="frr"
                     /locus_tag="IXR05_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAQ4259094.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(49819..50541)
                     /locus_tag="IXR05_000550"
     CDS             complement(49819..50541)
                     /locus_tag="IXR05_000550"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAQ4259095.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(50677..51558)
                     /locus_tag="IXR05_000551"
     CDS             complement(50677..51558)
                     /locus_tag="IXR05_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAQ4259096.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(51657..52439)
                     /gene="rpsB"
                     /locus_tag="IXR05_000552"
     CDS             complement(51657..52439)
                     /gene="rpsB"
                     /locus_tag="IXR05_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAQ4259097.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            52798..53277
                     /locus_tag="IXR05_000553"
     CDS             52798..53277
                     /locus_tag="IXR05_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAQ4259098.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            53494..54585
                     /gene="phnW"
                     /locus_tag="IXR05_000554"
     CDS             53494..54585
                     /gene="phnW"
                     /locus_tag="IXR05_000554"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAQ4259099.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            54578..54706
                     /locus_tag="IXR05_000555"
     CDS             54578..54706
                     /locus_tag="IXR05_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAQ4259100.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            54710..55255
                     /locus_tag="IXR05_000556"
     CDS             54710..55255
                     /locus_tag="IXR05_000556"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAQ4259101.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(55709..57400)
                     /locus_tag="IXR05_000557"
     CDS             complement(55709..57400)
                     /locus_tag="IXR05_000557"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAQ4259102.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(57820..58767)
                     /gene="arcC"
                     /locus_tag="IXR05_000558"
     CDS             complement(57820..58767)
                     /gene="arcC"
                     /locus_tag="IXR05_000558"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAQ4259103.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(58882..59901)
                     /gene="argF"
                     /locus_tag="IXR05_000559"
     CDS             complement(58882..59901)
                     /gene="argF"
                     /locus_tag="IXR05_000559"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAQ4259104.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(59992..61221)
                     /gene="arcA"
                     /locus_tag="IXR05_000560"
     CDS             complement(59992..61221)
                     /gene="arcA"
                     /locus_tag="IXR05_000560"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAQ4259105.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT        17052 a        13100 c        10621 g        20569 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
     4921 tttttttact tttccgatgc tgtatccaat gcctcgcttc tttcagctaa tgcacgttcg
     4981 atcgttcgat ccgctaaaat agattgagca tcgatcactg ggtaatgatt atcttcagca
     5041 aattcatgca tcaaagataa ttctgtgcaa cctaggatga ctttttcaca gtttaggcgc
     5101 tctaccgctt cctctaagat ttcgtaatag agctcttgat tcaaataatc cgattccttg
     5161 atctcatgat agatcaggta attgattttt tcttgaagcg cagtatcagg aatcactgtt
     5221 tcgaaaccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
     5281 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
     5341 ggcatatgca agataggaat atccgttgcc gcttgtaact cttcaaaaaa gtagtgtgcg
     5401 gtgttacaag tcaacacaat gaagtttggt cgcaataaat tttgtttctc aatatcatcc
     5461 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
     5521 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
     5581 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
     5641 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
     5701 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgatcg gtctttttca
     5761 taaaatacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
     5821 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
     5881 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttgaa cactcgatct
     5941 tctgtgacaa aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
     6001 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
     6061 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
     6121 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
     6181 tctaatagtg gatgaccaag gcacatcatc cgaacttgat gatcttcatc tacatacgca
     6241 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
     6301 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
     6361 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
     6421 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
     6481 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
     6541 aagcttactt tattgatcag cctttcaaat aaagaataat caatatatgg acagataaaa
     6601 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
     6661 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
     6721 tcgataaata cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
     6781 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
     6841 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
     6901 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
     6961 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaagtcctc
     7021 cgattgctca attctttttt gaacggattg aacttatagg aagtttttat ctataccaat
     7081 cagtgtagaa agaactacca tgtaatgatt ctagaacact gatattaata aaacaagcaa
     7141 aaattcattt ttttatgttt ttttaactat ctcagctatc tatcctcttt ataccattat
     7201 ttttttcaaa tagtgacctg tataactttc ttttacgtta atgatttctt ctggtgttcc
     7261 agtcgcaagg atcgttcctc caccttctcc accttctggt cctaaatcaa tgatataatc
     7321 tgctgttttg attacatcta gattgtgttc aatcactaaa actgtgttac cagcatctac
     7381 taatctttgt aatacatgca acaagcgggc gatgtcatcg ctatgaagtc ctgtcgttgg
     7441 ttcatctagt atatagaaat tctttccatt agagattttg tgcaattcac tggcaagttt
     7501 catccgttgt gcctcaccac cggacaatgt cgttgctggt tgccccatcg tcacataacc
     7561 taagccaaca tcaacaatcg tttgcagttt gcgatgaatc tttggaatgt gcttgaagaa
     7621 ttctacagca tcctctactg tcatttccaa aatatcagca atgctttttc ctttgtaatg
     7681 cacttctaat gtttcagaat tatatcgttt accatgacat acttcacaag gaacatagac
     7741 atcaggcaaa aagtgcattt cgatcttaat aattccatcc ccgcgacaag cttcacaacg
     7801 accgcctttt acgttgaaac taaaacgccc tttcttataa ccccgcattt ttgcctcgtt
     7861 cgtttgagca aataacccac ggatatcatc aaatacactt gtataagtcg ctggattact
     7921 tctcggcgtc cggccgattg ggctttgatc gatatcgatg atcttttcga tactttcgta
     7981 gccggaaatt gtcttgaatt tacctggctt agcagaattc ttatttaatt tttgcgctaa
     8041 cgatttcttt aagatactat tgaccaatgt actctttcca gaaccagaca cacctgtgac
     8101 tgctacaaat tctcctaatg gaaattcaac actaatattt ttcagattgt tttctgaagc
     8161 accagtgatc ttgattgctt tcccattacc tttacggcgt tcttttggta cagggattga
     8221 ttttttccct gaaagatatt tccctgtcaa agaattttca tcattagcta cttcttcagg
     8281 agtgcctgca gccacgattt gtccgccttg ttctccggcc ccaggtccga cgtcaatcaa
     8341 ataatctgct gcccacatcg tatcttcatc atgttcgact acaacgaggg tgttgccaag
     8401 atcacgcatt ttctttaatg agccaatcag tcgatcgttg tcgcgttgat gcaatccgat
     8461 cgatggttca tctaaaatat acaaaactcc agaaagattc gatccaattt gtgtagccaa
     8521 tctgattcgc tgcgcttctc ccccagataa tgttccggaa gcgcgactca aagttagata
     8581 gtctagtccc acattttcca agaatgaaag tctgtcattt acttctttta aaatcggttt
     8641 ggcaattact ttctcttgtt cagataacgt taagtttgag aagaaatcta ctgctttttg
     8701 aatagacaac tcatttgttt gcccgatatt cgttccattg atttgaacag atagagcttg
     8761 gggattcaat cgataacctt tacatgtctg acaagttaat tctgtcatat aaagacgcat
     8821 ttgctcacgc gtgaaatcac tgttcgtatc atgataacga cgctcgatat tcttcaatac
     8881 cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa tcattttcat aatggaaatg
     8941 gaaaagatca tctgtcccat tcaagatgat ctcctgatgc tcttccggta attcttcgaa
     9001 tggtgtatct aaatcgatac cgaaactttc acaagcctgc gctaacattt gaggataata
     9061 ctgagagctg attggattcc atggaacgat agcaccttga ctaagtgtct tcgttctatc
     9121 tggaatcact aaatcttgat cgacttctaa tttgacacct aaaccatcac agtctggaca
     9181 agctccaaaa ggcgcattga atgagaacag tcttggttct agttcgccaa cagtaaatcc
     9241 gcaataagga caggcatagt gttcgctaaa caacatttct tcttcaccga tcacgtcaac
     9301 cagagcatag ccgtctgcta atcgcagggc cgcctctaaa gaatcaaata ggcgagaacg
     9361 aatcccttct ttcacaatga tccggtcgat gacgatcgcg atatcatgtt ttttgttttt
     9421 ctccagctca ggcacttcac ttaaatcata gatctcacca tcgactcgaa cgcggacgta
     9481 tccctctttt tggattcgtt cgaatatttt tttatgttgt ccttttttct ttaccacgat
     9541 cggtgccaac acttggatct ttgtgcgctc aggcaaagcc attacttgat ctgccatttg
     9601 atctactgat tgactggtaa tctcgatatg atcgttggga caaatcggat gtcctacacg
     9661 tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca gtacctactg tcgaccgagg
     9721 atttttactt gttgttttct gatcaataga aatcgccgga ctcaatccgt cgatgctatc
     9781 tacgtccggc ttatccattt gtcctaaaaa ctgacgagca taagcagaaa ggctctctac
     9841 gtatctccgc tgcccttcag cgtacagcgt atcaaatgct agggaacttt ttccagaacc
     9901 ggacaaacct gtaacgacca cgaatttatc tcgtggaatc gttacatcta tatttttcaa
     9961 gttatgggca cgtgcaccat gaatcgtaat tttatcgtta gccatgttgt cctcctactt
    10021 tgaagctttt aattctaaaa tcatatctcg cacattcgcg gctgtttcaa aatccaaagc
    10081 ttttgccgca tctttcattt ctttttctaa tttcatcaat aacgtgtctt tttcttcctt
    10141 cgtcatttct tcgtacgaga cttgtaccgc ttcttttgta tcatcttccg attctttcgt
    10201 aatagaaatc aaatctcgga tttctttaat gatcgttttt ggaacgatcc catgttcttc
    10261 attgtacttc tgctgaatcg tacgacgtct tgacgtttca tccatcgcta gacgcataga
    10321 atctgttact ttgtctgcgt acatgattac tttaccttct tcattccgag cagctcgtcc
    10381 aatcgtttgg actaaggaac gttcactacg taaaaagcct tctttatccg catccaagat
    10441 agcaacaagg gaaacttcag gtacgtctaa tccttcacga agcaaattga ttccaactaa
    10501 cacatcaaat tcacctaatc gaagatctcg aatgatttct gttcgttcca gcgttttgat
    10561 atcactatgc aaatatttga ctttgatccc taattctttg aaataatctg tgaggtcttc
    10621 tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg tctttttcga ctcgttcatt
    10681 tatttcgcct actagatcat cgatttgtcc catgattgga cgaacttcga tcactgggtc
    10741 aagcagccct gtcggacgga tgatttgttg gataacggta tctgtttgtt catgttcata
    10801 tggtcctggc gtcgcagaga cataaatgat ctgattgaca tgtttttcaa actcttctaa
    10861 ccgaagtggc cgattgtcta aagcagatgg caaacggaaa ccgtaatcta ctagcatctg
    10921 ttttctcgct cggtcaccat tatacattcc tctgatttga ggcatggtta cgtgcgattc
    10981 gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat agcgtataag gcggttcacc
    11041 ttctttacgt ccgtccatat gccgagaata attttcaatt cccgacgtgt agcccatttc
    11101 taacatcatt tcaatatcgt aattggttcg ctgttctaaa cgttgagctt ccagaagttt
    11161 gttttcattt cgcaagacag ttaaacgctg ttctaattcc gctttgatat tcgctacggc
    11221 atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc gggaagattg ctacgtgttc
    11281 cgtttctcct aaaacttcac ctgtcagtgc attgacttct cggatacgtt cgacctcatc
    11341 tccaaaaaac tccacacgta aggcacgttc atctcttgaa gccggaaaaa tctccacgac
    11401 atcaccgcgc actcgaaaac gaccgcgctg aaaatctata tcatttcttt cgaattggat
    11461 actgactaag tcacgaatca actgattgcg atctagttct gctccctgtc gaatcgaaac
    11521 tacttgtttt tggtactcaa aaggcgagcc taatccaaaa atacatgaaa cggatgcaat
    11581 gacgatcaca tcatttcttt ctaataatga actagtagcc gaatgtcgta atttgtcgat
    11641 ctcatcattt acacttgaat ctttttcgat atacgtatcg cttgaaggca cataagcttc
    11701 aggctgataa taatcataat aagaaacaaa atattcaaca gcattgttag ggaaaaattc
    11761 cttgaattcc ccgtacagct gaccagccaa tgttttgtta tgggcaataa tcagtgttgg
    11821 tttattcact ttctcaataa gattggaaat cgtatatgtt ttccctgttc cagtcgcacc
    11881 taataagatt tgtgcttttt tcccgccgac tacgccatcc actaattggt taatcgcttc
    11941 aggctgatca ccagccggtt ggtatttcga gacaagctca aagtgtcggg aggtatctct
    12001 ctcaatcatt cttcgtcctc cttttcattc attccttttc attttacgac caataaaaag
    12061 aaaaggaaag caaaggcatt ccttactaaa aaattatacc acaccgaaca tactttcgcc
    12121 acttttttat cttattatac atgttatgtt ttataacata aaatgttaga aactcgcatt
    12181 tttttcattt tttcgagctt acagtcttgt ctgattcagc acttttcgcc tataataata
    12241 aaatattgga aatttaggag gttgattatg aaaagaaagc atttatttca ctcatttgtt
    12301 ttcttaatga caggacttgt gacatttgcg tttggtcatg ttgcacaagc tgacaacact
    12361 acaacggcag agtcaagcac aagcgagaca atgcaaaaaa tagagcccaa aaaagacgta
    12421 tacgtaattg ccagtgactc tgcttttgct ccatttgaat ttcaaaacgc aaagggcgag
    12481 tacgaaggca tcgatgtaaa attgatggaa aacatcgcca aactgcaagg atttaacatc
    12541 cgaatggact accgtggttt ctctgctgct ttgcaagctt tggaatcagg acaagcagac
    12601 ggaatgattg ccggaatgac tgtaacagat gaacgaaaga aaagctatga tttttctgat
    12661 tcttactttg atagcgggat ccaattagct gtcaaaaaag gagatacttc gatcaagtct
    12721 tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg gtaccgaaag tgctgaattt
    12781 ttaagcgacc atgaatctga atatggctat tctatcaaat attttgatgc tgctgatcaa
    12841 ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga tggatgatta tccggtaatc
    12901 ggttatgcga tcaaacaagg acaagaattg gaaacaccga tcaaaaaaga atctggcgga
    12961 aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc ttcttaatat gttcaatgaa
    13021 ggattgaaag aattaaaaag aacaggcgaa tacgataaga ttattaaaga atatgtagcg
    13081 gatggttcag aaacttccag tgagtcttcc actgctgatg aatcaacatt tcttggactt
    13141 atccaaaaca actatcaagc attgttgaaa ggactttgga gaacaattct cctaactttg
    13201 atctcctttg ctttggctat agtaatcggt gtgatttttg gattattcag tgtagcacca
    13261 atacgcgctc ttcgcacaat tgctagtatt tatgtcgata tcatccgagg aattccaatg
    13321 atggttcttg cgttctttat tttctttggg ttgcctggta tcgttggatt tacgattcct
    13381 gacttccttg ctggtgttat caccttgact cttaacgcaa gtgcttatat cgcagagatt
    13441 gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg aagcttccag aagtttaggt
    13501 ctttcttata atcggacaat gcaaaaaatc attttgccgc aagcgatacg catcatgatc
    13561 ccatcattcg tcaatcagtt cgttatctca ttaaaagaca caacgatcat ttccgcaatc
    13621 ggtgtagtcg aattgctgca aactggtaag atcattgttg cacgtacaac acaaagtacg
    13681 tatgtttact tgatcattgc gatcatgtac ttgattttga tcacagcatt gacaaaatta
    13741 gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa aaaatcttag ttgagcattt
    13801 agtcaaaaaa tacggcgata acacagtatt aaacgacatc aatgtatcca tcaacgaagg
    13861 agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa agtacattct tgcgttgctt
    13921 gaatcgttta gaagaacctt ctgacggtga aattattatt gacggcgccc acttgatgga
    13981 taaaagcaca gatatcaact tggtgagaca acatatcgga atggtattcc aacactttaa
    14041 cctattccct catctttcta ttttggaaaa catcatttta gcaccgatgg acctgaagaa
    14101 agaatctaga gaagaagcag agaaaaaagc aatcaaatta ctgcagacag ttggtctaga
    14161 agataaaaaa gatatgtatc ctgaaatgct ttctggtgga caaaaacagc gtgtggctat
    14221 tgctcgtgct ctagcgatga accctgacat catgcttttt gatgagccta cttctgcact
    14281 cgatcctgaa atggtcggtg atgtcttgaa cgtcatgaaa aagttagcag aacaaggtat
    14341 gacgatggtt atcgttacgc acgaaatggg gttcgctaaa gaagtggcca atcgcgtcat
    14401 gttcattgac gacggaaact ttttagaaga tggaacgcct caacaaatct ttgaaaatcc
    14461 gcaaaatgaa cggacaaaag atttcttgaa taaagtatta aatatttaat aaaaaccaaa
    14521 aatgcacggt cgccatgaag ggaccgtgta tttttatctt cttattttct cacctaatcg
    14581 tatcagccgc atcgcttgtt ttcctgcaca aacaagcaat cgctctacct gttccatcgc
    14641 ataagaaagt accatcggtt cattgatgat atcaagtaca tagtcgatac caccctcact
    14701 taattgagct tgatttttct tctccatatt atgtagttgt gggacaactt tctgacaatc
    14761 agcaattgtg tcaagaacgg atcaatcctt tattggagtt gctcgaaagg gtcttctctt
    14821 attacggaca ggctttgctc actgtacata gacaacaaat cattatccta gtcaatcgga
    14881 tttccagagc ctcattgcta tcattgcttg ataaaatcca gacaaagttt aataaaatgt
    14941 atcagttaca gctaaacttt ggaattgggt cgctttgtta tacagagcaa gagacaccgc
    15001 aatctttcct tcatgccaaa caagtttgcg aatggatagc tttccatcaa tctgtgaacg
    15061 agatccgctt ttttgaagat ttagacctcg ggatcgtttt accagcaatc ccgtcagatc
    15121 aacgaacatt atatgtaaaa cgtattttga aaagcctgac agaagaagaa gtacatttgt
    15181 tcaagaagac tttggcatgc ttcagtaaaa ataacggaag catcaaaaat tgctcagaag
    15241 aattatttat tcataaaaac accttgcaat atcgattgaa caagttccat tctctcactg
    15301 gttatacccc tagaaactat gacgattatc atattctaaa gctggctttt ttgttggtac
    15361 aaacatgaca actacaaaaa aaccaggcga acatatgatt gttcgtctgg tttttaatta
    15421 ttaatgactt agcgttttta ctagaaaaac tacttccgct ttttcccgcc aaaagcatct
    15481 ttaaacttat cgaagaaacc gtcttcttgc tgttcttcaa ctttgatgcc gccagcttca
    15541 gcgaatgcac gtaatgcttc tctttgttgt tcatttagat ttttcggtgt gatcagtttt
    15601 actttgacat gttggtcgcc tgttgcacca ccacgtaact tcggagcgcc ttttccacgt
    15661 aaacggaagt tcgtacctgt ctgtgttcca gcagggatct tcaatttcac atctccatgg
    15721 acagttggta cttggacttc atcccccaaa gctgcttgta caaaacttaa aggcaattca
    15781 tagtaaattt cagaaccttc acgatcaaag atatcacttt cttctacacg gaagaccaca
    15841 tacaaatcac caaatggtcc gccgttttct ccagcttctc cttgaccagc taaacgcatt
    15901 tgttgtcctt cttctacacc agctggtaca ttcactttaa ctgaatgtgc tttcttctca
    15961 tgtcctgagc catgacaggt tggacaaggt tctttgattt ctttccctgt cccatgacaa
    16021 acatcacaag tttgacggct catcactcgt ccaagtggtg tttggcgttc tacattaatc
    16081 gtacctgcac catgacattt atgacaagta gttggttgtg tgcctggttt tgcaccgttc
    16141 ccaccacaag tatgacagat ttcttcccga ttatacttga tttctttttc tacaccaaaa
    16201 atcgcttctt caaaagacaa gtcgaccgta tattgcaaat cagcaccttg acgaggcgca
    16261 tttggatcga ctgaccgacc gcctcctcca aagaaagagt cgaagatatc ttcaaaacca
    16321 ccgaagccgc caccagagaa gccgccgaat ccaccaaatc cgccaccagc tccaccagca
    16381 ccgtaatttg gatctgtgcc tgcatgcccg tattggtcat atgcagcgcg tttttgcggg
    16441 tcacttaaaa tctcatatgc ttctgatact tctttgaatt tttcttccgc atcaggttct
    16501 ttattgatgt caggatggta ttttttcgaa agcttacgat aagctttctt tatttcatct
    16561 tctgatgctc cttttgagag ccctaagact tcataataat cacgttttgt tgccataggc
    16621 tttcctccta ttggttctca tcattttcac gtcgcttgtt atcatatcat attttgtttg
    16681 aaacaaaaac cgatacttca aactattttt caaaagaaaa agccaaagta gcaactttgg
    16741 ccttctctcg aaattcagtg aactgattat ttatcgtcgc catcgacttc ttcaaaatca
    16801 gcatcaacga catcatctgc tccgccttga gctgcttctg ggttttcttg agcttgttgt
    16861 tgtgccgctt gttcgtatag tttaacagtc aagttttgaa cgatttcgtt caatgcatcg
    16921 cgtttagttt tcatttcttc gatgttgttt gcttcaacag cggctttcaa ttcatcgcga
    16981 gctgtttctg cttttttcac ttcttcttcg tccactttgc cttctaattc tttcaatgtt
    17041 ttgtccacag agaatagcaa tgcatctaca tcattacgta ggtcaacttc ctctttacga
    17101 gctttatctg cttctgcatt tgcttctgca tcttttacca tacgttcgat ttcttcgtct
    17161 gttagacctg aagaagattt gatcgtgatt ttttgttctt tttgtgtacc tagatctttc
    17221 gcagatacat ttacaatccc gtttttatca atatcgaatg ttacttcgat ttgtggaata
    17281 ccacgaggag ctgctggaat atctgtcaat tggaatcttc ctagagtttt gttgtcagca
    17341 gccattgggc gttcaccttg taatacatgg atgtctactg ctggttgatt atctgccgca
    17401 gttgagaata cttgtgattt acttgttgga atcgttgtat tgcggtcaat caatttagtg
    17461 aacactccac ccattgtttc gatacctaat gacaatggtg taacgtcaag taaaacaaca
    17521 tctttcacat caccagtgat cacgccacct tggatagcag cacccatagc aactacttca
    17581 tcagggttaa ctgatttgtt tggttctttt cctgtttctt tacgtactgc ttctacaact
    17641 gcagggatac gagtagatcc accgactaaa ataacttcgt cgatttctga ttgtgataaa
    17701 cctgcatctt ttagcgcttg acgtactggt acttttgtac gttctactaa gtcagctgtt
    17761 aattcatcaa attttgcacg tgtcaatgtc atttccaaat gcaatggtcc agattctcct
    17821 gctgtgataa atggcaagct gatttgtgtg cttgatacgc cagataaatc ttttttcgct
    17881 ttttcagcag cgtctttcaa gcgttgtaaa gccattttgt cttgagacaa gtcaatgctg
    17941 ttttcttttt tgaattctgc taccatgtag tcgatgattt tgttatcaaa gtcgtcccca
    18001 cctagatggt tgtcgccagc tgttgacaat acatcaaaga caccgtctcc tagttcaagg
    18061 atagatacgt caaaagtacc gccaccaagg tcgaatacta agattttttc gtcgcgatct
    18121 gttttatcta aaccataggc aagagcagct gcagttggtt cattgacgat acgttctact
    18181 tctagaccag cgatcttacc agcatctttt gttgcttgac gttgtgcatc attaaagtaa
    18241 gctggcacag tgataactgc tttttcgact ttttcaccta aatagtcttc tgcgaatcct
    18301 ttgatatatt gaaggatcat tgctgagatt tcttgtggtg tatatgattt accttctaca
    18361 tctactttgt aacctgcttc accgatatgg cgtttgattg atgaaatcgt atttgggttt
    18421 gtcacagctt gacgttttgc aacttcccct acttggattt ctccattttt gaatgataca
    18481 acagaaggtg ttgtacggtt tccttctggg ttagcgatga tttttgcttc gtttccttcc
    18541 aatactgcta ctgcagagtt agtcgtacct aagtcaatac cgataatttt actcataatt
    18601 aacgtctcct tctttaattg aaagtgtaag ttttatatcc gcacaattat tgtgcaacaa
    18661 tgaccatggt tggtcttaac acgcgatcat gtaatttgta gccttcttgt agtacttcta
    18721 caatcgtatc ggctggtgta tcttcagtcg ctggaacagt ttgtactgct tgatgaagat
    18781 taggatcaaa ggcttctcct ttagcaggga ttttttcaat tccttcttct tccagtgcgt
    18841 tacgcaaact ttccaagacc atttccacgc cttttttcaa acctgcccct tgatcatctg
    18901 acacttctgt ggctaatgca cgttccaggt tgtcaattga tggaagtaat tttttggcta
    18961 aatcttgtga acggtatttt tgtaattgct cacgctcatt ttttcctcga tttgccatat
    19021 ttgcgatttc agcacgagcc cgcaagtatt tatcttccat ttcttctaac tcagctttta
    19081 atttcgctgt ttcgaattct tccgcttcag cttctgaaat acccgaatct tctgcagctt
    19141 cgacatcgat ttccggttct ggctgagcat ctgtcatttc tttatctagt tcttcttgat
    19201 tttctttcac gatacagtct tcctttcatt attcagtcag ctgtttgatt gctcttacta
    19261 agaaagagag aacgatcagc tgcaaatagc ttcgttattc acattacgag tttgacaagt
    19321 caagcgaacg gtagtaatca gcaagtttag ctgctagttc tcttcgataa acatcgacta
    19381 gaccgaacat ccgagaataa ggcatactag taggccctaa caaggctatt gtacctcttc
    19441 catgaccatc tatctcgtaa cttgcttgaa tcatactcat attctgcaat aaatcattgc
    19501 ctaattcagc accaatcttg atatgaatat tgctatccat cggagtgatc atttgtgtaa
    19561 gtccgtctga gtctttcata aaagaaaaca tcgatttgaa ctgatcaaga tcttgacggg
    19621 gctcataatc caagagattc atttgtccac tgacataaac cttatcttca aaaacatgac
    19681 caagaacggt gtcaaataac tgagacatcc cttctgtcgt ttggaaatat ttatgaagaa
    19741 tcatcggaat ctccgtacga agtttatggt acaccgtcat cagaggatct ccgactagac
    19801 ggtcgtttac aatctgtacc attttttcta gttcctgact tcccatatat tcgggaagag
    19861 tgaacacttg gctttctaca ttccccatat ctgttacgac gatagcaata atctgtcgat
    19921 tattcaaggg tacgatacga aagccagtca gtcggcggtc ttttatttca ggtcccaatg
    19981 aaaaagtcgt atagcttgtc agctcagata atatctcagc agattgctta ataatctcat
    20041 tgatttcatg aaattctctg cctagagact gacgaatcag cagcaaatca tcttctgcta
    20101 cgcgagcagg ttttaacaaa tgatccacgt aataacgata gcctaaagca gatggaatcc
    20161 gcccagaaga agagtgagtc ttcaacagca atccttcatc ttctaatgct ttcatatcat
    20221 tgcgaatcgt tgctgagctg gccttgactc cctcagacat caatgttttg gaaccaacgg
    20281 gcacgccact actcgtatag tgttggatga tcagacgtaa aatgtcgttt tgtcgctttg
    20341 ttaacatctt cctcacctct cattagcact catatattct aagtgctaat ccacttataa
    20401 atatagcaag aagcccttct cctgtcaaga gaaagactcc attttttagc actctaaaca
    20461 caagagtgct aattctaaat aattgatgta aatccagtta tatcaacgtt tcaatagtcc
    20521 tttattgtat ttttgaactt tttttattta aattcagata aaaaacaaat attctttaaa
    20581 ctatttttca aacaaaaagc gctcaaacac attgttcccc aaaaaggtcc ctcttggtgt
    20641 caaataaaca cggtcttctt cattaacaag taacccttct tgctctaatt cccttagcac
    20701 atcaccgtac accgattcaa ttgttttttg atagcgatca tagaaatgtt ttttagtaat
    20761 ccctgttttt tttcttagtc ctaagaacat ttcttcttct atttgatttt ttcgtgtcaa
    20821 tttttcttct tccaataccg ggcgttcatt tgctcgtaat gggcgtaaat agtgttggat
    20881 tggtcctttg ttgcggtaac gaatatctcc aagataaccg ctagcaccag ctccaaaccc
    20941 aaaatagtgg tcattgttcc agtacatgag gttatgttga gattcatgtc cggagagccc
    21001 aaagttactt atttcatatt ggtgacgtcc atgcttttcc attgcttcaa tcgtctcttc
    21061 aaacattctg gtttccgttt cctgatcagg cagttcgagt cttccttgtc gtacccagtt
    21121 catgaacatt gttttgtttt cgaggatcaa tgagtacaaa gaatagtgag gcagatccaa
    21181 agccaaagct ttttccaaag tatccagata tccttctagt gtttgtcccg gtaatgcata
    21241 aatcaaatcg atgcttacat tggtaaaatt ttctgcttct aaaaattgca tagtttgata
    21301 cacatcttct gcggtgtgtt tacgtccaat ttttttcaat aagcgattat caaatgtctg
    21361 cactcccatg gataaacgat tgacgccata gtttttcatt acttgaagtt tttcacgggt
    21421 caaatcacct ggattcgctt ctacagtaaa ctcattacca ttttgaaaag gcaggatctc
    21481 tctagcacct gataacagtc gatcaagttg tttagcagat aaagaagttg gtgtcccgcc
    21541 ccctacgtaa agtgtttcta aattcgctgt cggatgactt tctagcatta ttttcatttc
    21601 attcagcagc atttccacat actcatctac tggctgccct tctaaaaaaa ctttattaaa
    21661 atcacagtaa tagcagatat gctcgcaaaa tgggatatga atgtacgcag aaaccttgtt
    21721 ttctgcggga tttattgttt ctatcattga aattctttct ccttacgtcg aaaagtcgtg
    21781 cctgttttcg accttcttaa aatcgcgttc aagcaccaac tcattgaaat aagccgcata
    21841 tttagaatca aggaaaccta gctctaaaaa tgcttgctta ttgtcatcgg agctacacgg
    21901 tgcttttaca gcctctcgat aaacggtaat cgcaaagctg accttcggca ttaagtcaaa
    21961 atctgcaaaa atatgaaaag ctattttcac agattcctcc ttaagtgctc agaccacaac
    22021 gctttgctta caacctctca tatacgcata ctaaacgtat ttggcgaaca aatccactaa
    22081 aaaatccaag aatcgacttc ttggatgatt ttttctttca ttaaactggt tacctagtta
    22141 tatatctcta gggttgtttt catgtctgag tgcccgatat gatttatttt tcgtttctat
    22201 aattactttt tgccttccag tttcttttaa tattgtactc aagcaagtgg gaattggttc
    22261 ttttgtcatc catgtatgca aaatgttata atgctggtaa acaaaaatga ttacctgtca
    22321 tttttattta gttcgtattt aattaagttg actatctgta tactctgtct aaaacttaag
    22381 aattgttgtt ttcgctgtcg ctacccaatt ttaatgaatg tctgtaggtt aaaactgttg
    22441 tccttgttat agatagtaaa ggagagcttg aaaatgaaaa ctgcgattac gtttctatta
    22501 gaggaatatg ccgattggga aggtgcttat attactagca cactaaacca aaatgagaaa
    22561 tggcaaaaca aaactgcttc tatccaatca gaggtcactt ccattggagg attaaaaaca
    22621 aaaatcgatt acttaatcga acaaatacct gaaaaagttg acctttttat tatgatcggt
    22681 ggcaattcat gggacataaa aaatcatcat ttatatcaaa taatcgataa attgttaaaa
    22741 acagacgtac cagtagctgc tatttgtggg gcagttgatt atttagctca gagcggatta
    22801 ttgcaaggtt acaaacacac cggaaatgcg caatttcctt ggttagaatc ggaaaattat
    22861 cagaataaag aagattttat agaacaacaa gctgtgaaag atcgtaattt gattactgcg
    22921 aatggaacag ctcctataga attcacagac ttgattcttc aagcagtcca ttttgaaaca
    22981 gaagaaataa gagaaaaaac gattcgtcta tacaaacttg gattctatga ttactataaa
    23041 aagtacggag atcctttctc ctaatcattc tcttcaatta aatactcctt atcaatagtg
    23101 tgacaagtaa ttttactgat gattatttgt cacacttttt ctgacattta tcaaagaaga
    23161 tacactctat ttatattcat agacaaggtt ttacggattc aaaaattcag gattatgcta
    23221 tactggtatt aaaaaaataa tgaggtattt tatatgaaaa agttaggttt tattttattg
    23281 ttggtctctt tattccttgt aggatgtacg tctcctagta aagaaaatag tgatccatct
    23341 gcgaccacag acaaaagttc aatcagacaa accagttcag ctgaaaaatc aagtactcag
    23401 aaatcagctt ctactgaaac gaatacatct tcaacaagca gtaaagtctc agagcccaat
    23461 acttcttcta catctagtag tacagttgag acaaatattt cttcttcaac aatagacaca
    23521 acctcctcac agtcttctca gtcaatagat ccgttagcag gatattctga tctacaaatt
    23581 gagtacgcac gtgtttggct agctattaga ggtaatactt ttagagatac atcgggtgat
    23641 ttcgaattac atgttattca ttatcctgca ggaacaccta tcgcccctta tgatgcaggg
    23701 agtgcagtct atccgaaaga tgtggttatg ctcactggga aatacagtta ccagggagtt
    23761 ttagtgtatt caagtaacca tgacgggaca atcactagtt atccagttcc ttcacattgg
    23821 caaatgcctg cagatcaaac atcttatcca gcgttcatta gagaaacaac tcaagaaatc
    23881 attgataatg catctgtagt agctattcct acaggaaatc ccaatgacgt gaaacagtta
    23941 atcgatgtga cagttataga taattagact ttctaatatg ttatacaaaa agaagctgac
    24001 agcattttgt cagcttcttt cactttcttt tctatttaga tttattggtc tttgatagac
    24061 tccaaggcag gaaaaaattt tttaaataaa cgtttgcaaa acagtcgctt ttctatcttc
    24121 taccgctact tctgcatagg caccattaat caatgtcagt tgtggcggta catgaccaca
    24181 atcaatatca tacaagatcg gtagttttaa ttcctttgac agatcttcgt atacatcctt
    24241 cattttataa tctaacaaat cctctgccgc acttctaccg aacatgatcc ccgagctgcc
    24301 atcaaaccag cctgccagtt tcatctgaac aagtgatctt cttaaatcaa ctgacgatag
    24361 ctcacagttt tctagaaacc acaagatcgg ctttccatca ttatactttc ttttaaaaga
    24421 ttggacatct ccataaggag taccgattaa atgcctgatc gtatcaatac aaccacctaa
    24481 taatcgtccc ttcatcctta ctgcatctcc gctgactgat tgccaatttg ttggttcagt
    24541 gagatggaaa acagaagatg atgaatgctc atggggccac actttttgat acttttcaga
    24601 agattgctgt agaatcgatt ctccttctct tgttttcagt acactttccc acattgctgt
    24661 cgtttcatcc aagtactctc ctcttaaatc aataaggtta gttccatgtg cagtggctat
    24721 ccctgttttt aatgtgacag caagtagcaa cgtactaata tctgaataac ctactatcca
    24781 ttttggttgt agagcatcaa aatcgacaaa atcgagaatc tcaatcaata attctcctcc
    24841 ccaagtcgga aagatcattt ggatattttc atcttgcatc atttgattga attcatctgc
    24901 tcgttttctt gctggacctg atttttcctt atcttgcgtc caaagcgtct ttccagtaac
    24961 tacttggaaa gatttttctt ccattctctt taaagctgat tcgagtaacg aatggtgttc
    25021 ctctgatacg cctgaggatg gtgcagtaac cccaatcgtt gcatttcttt ctaataatgg
    25081 ataacttatc atgttgcttc acctccaagt atgcactatt ttacttggtt aattgttttt
    25141 ttcgtttgcc ggcatcaaaa atatcggcat ctcaagtagc tggatgattt tgtttaagtc
    25201 aaccgtttgg atgaccatcg tttgatctgg tctacctggt gcaaaaacaa gtttttcatt
    25261 tgataagagc tcttcatcaa taataatcgg aatctgtttt tcataaccaa acggagaaac
    25321 agcgccctgc ttttgtcccg tttgttcttc catgcgttct gatgaaacaa tagaaagcct
    25381 tttaccgacg atcttcccta atgctttgaa atccgtttgt ttcgtagtaa aagtcagata
    25441 tacgtagtta ttatcttttt tatcttttaa gaataagctt ttggtctctg tacctgtaaa
    25501 tccttgttct ttctttatta ccaaagcatc ttcatttgta taaatggctc gatgatgata
    25561 caactcaaaa tatatatttt cgtgtaagaa tttctttgcc aagtcaatca tttttatgtc
    25621 tcttttctat tttattattt gagacatctt atcatataaa tatagcggtt acaacattac
    25681 ttgtgttttg ttcgtttttt atacataact attgtttttc tggtaaaata aatcaaacca
    25741 cttaatggag gcgttttaga atggaaaaat ttcagccgat catcaatcaa atcaaagaaa
    25801 aagaacatca acaaaagatc aaagaccttt ttgctaagat aacagaaacg tatccccagc
    25861 tagacacaac tgtaaaatgg aaccaaccta tgtttactga ccatggtacc tttattattg
    25921 catttagttt tgctaaaaat catttttcta tcgcaccgga aaaagcagcg attcgtgccc
    25981 ttgaaaaaaa tatccaagaa gcaggctacg tatatacgga taacgtcatc aaagttcctt
    26041 ggaaaagtgt aatcaactgg gaattgattg aacaattgat ttcatttaat attgaagata
    26101 aaaaaggtca tgataaattt tggcgataaa gctttatacg aataaacctt ttactggcga
    26161 ggaaactatt catcacctta tacaggtttt gttcaatcct atccttttta tcatccctgg
    26221 ttaaacactt aattgacaaa gtatctgcta tttttataag gagtctttct tgtgctgaaa
    26281 aaaatcactg attgaatggc tttgaatttt ctacatagta aaattatttt ttcagcaatt
    26341 ttcctgcaaa acttttgaat aaggaaaaaa tacgagaaaa tatcagtgat ctttcataat
    26401 actgcccatt attttcaggt atatttaaat ataatatcac tttaggagag aacgaatttc
    26461 tttagagaaa taaaagttag aattttctga cttgattttt acaatgacct taattaaaat
    26521 cgttctttct acatttcgtg attaagcaaa tatcaactaa gtcagtagaa ccattcacat
    26581 aggagggtga acattgaaag atttttactc agtaaatgaa ttagccgaac aattaggtgt
    26641 tactacacgt tctatcagaa attatcttca tgaaggaaaa ctaaaaggaa caaaggttgg
    26701 cgggcaatgg aaattttctg aacgtaatct ttttgagttc ctatacggag atcaagcaga
    26761 ggaagcagca aaagaaatgc agcgattcat gctaaatgca ccaatcacga tgcgtttcaa
    26821 ccttcaatat cgtgatttta cagcaatcaa tcaattccga gaacaattag tccagtacca
    26881 taacgatgtt tacgcaaata aaaaagaccg tcttttacaa tacgatcttt ataaagacaa
    26941 tcatgcggag atactaatcg gtggtaactt caattatgtc gtaaacttta gtcaatggat
    27001 caatgaaaaa ttattgatcc agacagatat ttcccttgta tcttaaacaa ttaaaaagcg
    27061 ctagaaattc cagagatgtt ggaaattcta gcgctatttt tttataagta cttactgttt
    27121 ggttcaaaca aatatttttt taataaatga aattttacca tctttatcct caaataaaga
    27181 ccgtgaccat gcttcctact acgatcagca ataatccgat aatcgttaat tttttttctt
    27241 ttggtgtctt attttcatgc aggatgtaca taccgcctaa tgtagagata actacgttta
    27301 gctgtgtaat gatatatgca gtagcaaccc cattttcatt tgctgaaaaa atataagcca
    27361 atgctgacac actaaagatg gctccaacga tcgttgcttt ccaactcttg tcttcagaaa
    27421 atgcggttgg tttacggaaa atcacataaa tcactgcccc taaaaagaca ccgatcattt
    27481 gcggaaagaa aatggaaagt ccgcttgcat caactagttt aggcaatgca ctgtataccc
    27541 aataaccaat acttgttgat gctaatagac taattccttt tgtgataccg cctttttttc
    27601 caggatcatc actgattgcc gttaaagcag aaccaaatac aagaagaatg attgctgctg
    27661 ctccaatgat tttccccata cttccagacc attctccaaa agcgaagaca ccaatcaacg
    27721 aggttccgac taactgtaat gcagtcgaaa ttggcatcgt tttagaaaca ccaatcaagt
    27781 tgaaagatgt atactgtcct gtttgtccaa taacccaaaa tgcaccagaa agtaaactaa
    27841 tcaaaaatgt agtcactgaa ataccagctg gagaagcgaa taattgaacg agtaagccga
    27901 caagcaccgc tccaatacca gttcctaata tctcatttgt tggtctgcca ccaatctttt
    27961 tcaaaatcag tggctggatc ccccagccaa ctgccgggat caatgcaatc aataaaccca
    28021 tttttattca cccttatcct tttccacctt ggaaagaagg atataaagtc atcccaccat
    28081 ctgcaaatag tgtaatacct gtaacataac tggattcgtc tgaagccaac catgcagctg
    28141 tcgccgctat ttcttttggt tcacctacgc gtcctagtgg gatcatactt tccaagagtt
    28201 ctttttgttc aggatcatca aattttgccg cattaatagg tgtacggata gcaccagggc
    28261 ctatactatt gattctgatt cccttcggtg catactccat tgctaccgtt tcggtaaata
    28321 attttacccc gccttttgaa gcagcgtaat gagcaaacgt tggccatggg atctgttcat
    28381 gaacagaaga catattgatg atatttcctt ttttattatt ctctgtaaag taatttaaag
    28441 ccgctttcgt tccgataaaa acgccagtca aattgacttt taacactctt tcccaatctt
    28501 caaggctaag ttcatgggtt ggatgctgat tttccatccc agcattatta acccaaacgt
    28561 ccagtgtccc aaaattttct aaagccgtat caagtaaacg ctgtattcct tcttcagaac
    28621 tgacatctgc ttgtacagag actgcttttc cgcctgcctc ttcgattgct ttgactgctt
    28681 tttctgctcc ttctttatcc gagttatagt tgacaactac attcattttt tctttcccga
    28741 atcgttgagc aatcgctgtt ccaatcccct ttgagccacc agttactact gcgactttgt
    28801 tttctaattc cttgtacata gtacccactc ctttttcata cctaaacctg ttattacgga
    28861 taacttttat ttccgcctta aagtgagtgt acaccaagat atatagtcta aagcaaatga
    28921 tacgctctag caatcgtttt catgaattgc tagtgtcctt ttatttctat aaagaaagag
    28981 gttgtgacag aagtggtcag cttcaagaaa tttcggctta tttccgaaga agctacttct
    29041 gaaaaaccat ttatttggaa aaaaaggctg tgacaagact tttgtcacag cccctttcct
    29101 gggcttattt atcacccatt ttattgtaat tgctagttat acataaacaa gagattttat
    29161 gcataatgtt ttattgctga gaaaaatatt cagctgttgc ttgttcatcc tccttgagtt
    29221 gttcaatcaa ttcctctaca ctagaaaatt tcacttgatc tcttaaaaat tgattccagc
    29281 gtaccgcgac atgttcacca tagatatctt gattaaagtc caaaatatac aactctacag
    29341 tcagctcccg tccttcaccg aatgtatcat tatgtccaat tgaacccatg gctggatacc
    29401 atgtttcccc aatttttatt tccgacacat aaacaccttc tttaggcaaa tgaaccgtgc
    29461 tctttacttt gacatttgct gtagggaatc ctagtagtct gcctcgtgca tcgccatgga
    29521 caactacccc ttctacctca tatgtgcaac ctaatagttt tgctgcttct tttacttgtc
    29581 cgctgtctag taatccacga atacgggtag agctgatttt ttcaccttgt tcttcttctt
    29641 tagaaactgt gacgattttg aatcttcctt tggcatattc aggaaaatga gcgacatctg
    29701 caatgtcttt tggtccatac gtataatcaa aaccggaaac agcatatttt gcatgtaacc
    29761 ctacgatgta ttgatcaaca aattcctgcg gtgctaaatg agcaaaagaa gaagtaaaat
    29821 caacttcata taaataatct atacccaaag cggccatttt ttcttctttt tgcttaaggc
    29881 tagtcaaata tttcacgctg ctaggatcga tctttttaaa gacaatagat ggatgctgat
    29941 tgaaagtcat caatgctaat ttcaatcctt ctttttgtgc aatttccata cctgtcttta
    30001 tgactttctg gtgtccgata tgcacgccgt cgaaaaatcc cagcactaaa acgacatcgt
    30061 cttctggaat ttgttctgat tggtaaggat gtctgatctt gatgatattc attcgttatt
    30121 cctcatttct caatacttta ctaggtttta atttgttttt ttctttcggg tttggctgat
    30181 aaatactgac aacttttcct ttataaaaca aagcaatttc ttctgacggc atttctggga
    30241 gcgcaaatac agtataatca agtctcatac cgttttttac tttctgccat acttcatcag
    30301 taatatctac tcgtttgaac cgttccactc ctttttctat tggcagcaaa caatcatcga
    30361 ttgtcccatt tttcacagct tgagctactt cttctaatgt cagagcatcc ttctgggaca
    30421 taccggcact tgctgttcgg gtcagatcag acatgtgcgc agggtaacca agtttcttgc
    30481 ctgtatctac agctaatgtg cggacatagg ttcctttccc gcattctact tcgaagcgcc
    30541 aagaaatggt tcctgtcact tcgtctcttg tcaattcact tgtccggata aaacggtaaa
    30601 tctgagcctt tctaacagga cgctccactg tttcattatt gcgggcatat tcatataacc
    30661 gcttaccgtt gacttttacc gctgagtaca ttggtggtat ctgggtgatc tcaccaataa
    30721 atgaagccat cacttcatct attttttttt cagataaaga catatctact ggttttgttt
    30781 ctacccgttc tccggatcga tcttccgtcg ttgtactgaa acctagagtt atctcgccta
    30841 catagatttt cccagaatct gtcaaatatt cgataacttt tgtggctttt ccaatacaaa
    30901 tgggcaacac accgtctacg tctgggtcaa gcgtaccccc atgtccgatt tttttcgtat
    30961 gtaagatttt tcttaatttg aatacgcaat catgacttgt cattccgcgt tctttccata
    31021 aaggtaataa cccgtccatg tcttttctcc atttcatttt tgatttaact gaattattat
    31081 aacacattgc atcaattact gacgaatttg acatcataat gaacggtttt tatttttcgg
    31141 caataaaaac gtaacaaaat tcatgctcac gtaaatagaa atcatgttat gcttttttaa
    31201 aggagggaat agaatggaag attttttctt tgcaccattt gattggattt atgggtggct
    31261 tacaggtaaa tagtttggtt ttcacttccc aaaaacgaaa aaaaagactg gccattcttc
    31321 cagtcttttt tccgtttttt ttatttattt tttcagtttc ttaatcaatg taaaaaattc
    31381 tattttgcgg gatcgatttt atcattttat tggtcaagat ttttccattt ccaatccaat
    31441 acttctggca gatcaatacc attttcacga atatagtttt gatgttcttg taatttctga
    31501 tccatttttt tcgcaaaatc ttctgcttga cttcctttga tttttaaagc tgcgtctttt
    31561 gccaaatgat aacgatcaag ttcatttact acacgcatgt caaatggtgt cgtgatatct
    31621 ccattttctt tgtagccatg aatcattaaa tgatggttat gacgatcaaa gaaaatcgtg
    31681 cggaccaatg tttcataacc gtggaaagca aataagatcg gtttgtcttt tgtaaaatat
    31741 tgatcaaatt cttcatcgct caacccacgc ggatcttgac ttggatgacg taatttcaat
    31801 aaatctacga cattgatgaa ccgaattttt agttttggga attcttccag cagcaaagtt
    31861 acagctgcta atgcttctaa gttagattcc gttcctgcag cagcaatgac caattcaggt
    31921 tcctcctctt ttgctgtcga agcccaatca atgattttca agccttcatt cactaagacg
    31981 gctgcttctt ctgctgagta aaattgagca cgcggatgtt tggaagagat gatcaaattg
    32041 attttttctg acgagcggaa tgctttatcc atgactgcga gcaatgtatt tgcatccgca
    32101 ggcagatatt cacggatgaa ctccgccttc ttttctgcca aatgtgtcaa tattcctgga
    32161 tcttggtggc tatatccatt gtgatcttgc tggaagactg ttgagcttgc aatgagattt
    32221 agcgaaggat aatcatttcg ccaagaaagg tcatgtgatt tccgcatcca tttgaagtgc
    32281 tgagtcaaca tagagtcaac cactcgcaag aatgattcgt aacttgcaaa aaaccatgcc
    32341 gtccagtcag aacgtaccct tctaagaacc cttcatcttg gtgttccgat aattgactgt
    32401 cgatgacgcg accagatggc gaaagccatt catcattttc tggttcgatt ttttccatcc
    32461 attggcgatt tgtcgttttg aaaacttgat tcaatcggtt tgattttgtt tcatctggtc
    32521 caaatatacg gaaattttct ggatttttct caatgatctc gcgaacgaat ttaccaagtt
    32581 cggtcatatc ttctgcttta acggagcctg gtttttcaaa ttgcaaagta tattttttcc
    32641 aatctggcat aataagcggt cttggatcga ttccaccatt ggtgatagga ttttttgcca
    32701 ttctttggtc accagtaggc gcgatttctc tgatttcttc taaaatacgt ccttgtgcat
    32761 caaataattt ttctggttca taggatttca gccaacggag taaagcatct gcatgatcca
    32821 tatgttcttg atctacagga atcggtactt ggtgtgctcg gaaggttcct tcaattggtt
    32881 ccccgtccca ttcttttgga ccggtccatc cttttggtgt gcgtacgatc aatactggcc
    32941 attttggcat cacgacatct gttgctgtct tcaggcgagc ttctttttgg atggatttaa
    33001 ttttctcgat tgcttgatcc attttttcag ccataacagg atttaatttt tctgaatcat
    33061 ttccttcaat aaagaaaggt tcccagccaa gtccgttaaa gtaatttgct aattctccat
    33121 ctgatttacg tgccaagatc gttgggttgg ctatttttgc accatttaaa tgaaggatcg
    33181 gtaaaacagc tccatctatc actggattga taaagacatt tgagaaccag cttccagcta
    33241 aaggaccggt ttctgcttca ccatcaccaa tcacgacagc agagattact tcaggattgt
    33301 ctaatacagc tccgactgca tgtgaaagag agtatccaag ctctccgcct tcatggatag
    33361 aacctggtgt ttctggtgct gcatgagaag caatgcctcc aggaaatgaa aatcgtttga
    33421 ataatttttg cattcctgtc tcatcttccg ttacttctgg atagatctct gtgtaacttc
    33481 catctaaata agcattcgat accatgactt gtccgccgtg tcctggccct tcaatataaa
    33541 acatgttcaa atcatattta ttgatgactc ggttcaaatg gacataaata aaattttggc
    33601 caggaatcgt tccccaatga ccgattggat gttttttgac atcttcgggt ttcagtgtac
    33661 gtctcagtaa ggggttatct ttaagataaa gttgcccaac agaaagataa ttagcagcac
    33721 gccaccaagc cgtcatttta tcaaagtatt ctttactaga ataatccata cataacactc
    33781 cttttcatta ttactcttat tctagcgcag atactcccaa ttgaaaccta ataagcactt
    33841 ctgttcattt gtttggattt tatatctagc caaatgaaca ggtataaaaa accacgaaat
    33901 ttttcctttc gctgacgttt tttacattga tccaaaaaac ttgtcgttat cacaatggct
    33961 gttccgcagt tcatttcgct cctcatcatg cataatttgc tgaatgacgc tgggccagtt
    34021 aacacattgc tggaaaactg gggctggatc gagcaattcc tttcctgatt gatccgtttt
    34081 atgtaaaagt ctctgttatc tttgtcaata tgtgaattgg tatcccagct actatgctaa
    34141 tttctacagg gattatccaa aatttggatc gtgaccaaat cgaagcggcg taatcggaaa
    34201 tatcaataac ttcaacgtga tttttctttt aactgtcaac ggaccgacaa actcaaactt
    34261 ttatggtgca ggttccactg atcttctagt tacttggcta tacctgactg tcactaaaat
    34321 agattacaat ctagcttccg ttatcggtat cttgatcttt atctatatgc aaaaatttat
    34381 atactactag aaaaaagaaa gtcgaatttt ttacttttct ttttctcttt tttggttagc
    34441 tgacacgccg caagactaaa gtcatggaac tcttaggtaa tacgtcttaa tgaaaacaaa
    34501 aaaatcccgc aacccctgat ttcacaggat ttgcgggagt ttttgattag tctttgttca
    34561 agtcgcgaag caattcatcg atatggttgc catagacaac tgattcatca agttcaaaga
    34621 acaattcagg tgtcttataa atacttagat tgtgccctaa ctctcgacga atcaatcctg
    34681 atgctttatt caatccatct tgtgctgttt tcttatctga tgctaagtca gataaaatgc
    34741 tgtaatagat cgttgcttgc tgtaagtccc ccgtaacttt cacatctgtg atcgttacgt
    34801 tctccacacg agggtcacgg acctttttgc gcaaaatatc attgacttct tttaagattt
    34861 cttgaccgac tcggcggtca cggtagttag ccataatgat tggcctcctt ttatcagttt
    34921 ttagtcattt ttgacttctt ccatgataaa tccttcaatt acgtcatcta ctttgatgtc
    34981 attgaatttt tcaatcattg caccacattc ataacccatt ttgacttctt tcacgtcatc
    35041 tttgaatcgt ttcagacttg caagttggcc ttcatagatt acgattccgt cacggattac
    35101 acggacaccg ctatctctac gaatatatcc ttctgttaca taggcacctg caatcgtacc
    35161 aactttagaa actttgaagg tttcacgaac gatcatttga ccggtgattt tttcttcaaa
    35221 ttcagggtct agcatccctt tcatcgcagt ttcgatttct tcgatggctt tatagatgat
    35281 acggtgaaga cgaatatcga cttcttcagt atcagcttgc acttttgcct gcggtgtagg
    35341 acgaacgttg aaaccgatga taatagcgtt gctggctgct gctaaggtta catcactttc
    35401 attgattgct ccgacagctg aatggacgat ttttacacgg acaccttcca catcaatctt
    35461 cttcaatgat gcagccagtg cttctgctga accttgtaca tctgctttga tgattacgtt
    35521 aacttctttc aattcgcctt ctttcaggct ttcaaataag ttatccaaag tcacacggct
    35581 tgtggcagca cggttttcta ataatgcacg tttcgcgcgt tcttcacccg ctgcacgtgc
    35641 tgtcttttcg tcttcgaaga ctacgaaacg gtcacctgct tgaggtacat cattcaagcc
    35701 agtgatttct actggcgttg caggtcctgc ttctttatcg cgacggccaa gatcgtttgt
    35761 cattacacgg acacgtccgt aagtattacc gacaacgatt gggtcaccaa catgaagtgt
    35821 tccttcttgg acaagtaagg ttgacacagg acctttacct ttatcaagac gtgcttcgat
    35881 cactgttccg attgcgcgtt gtgttggatc tgcttttaaa tcttctactt ctgcgactaa
    35941 caggatcatt tccagcaatt cttcgatgtt ttggccgaat ttcgctgaga tctcaacaaa
    36001 gatcgtttct ccaccccatg cttcaggaat taactcatac tcacttaatt cttgcataac
    36061 atgttgaggg tttgcacctg gtttatcaat tttatttaca gcgacgatga ttggaacgcc
    36121 tgcagctttg gcatggttga ttgcttcaac tgtttgtggc atgacgccat catctgcagc
    36181 aacaactaag atcgtgatat ctgtgatact tgctccacgt gcacgcatac ttgtaaaggc
    36241 cgcatgtcct ggtgtatcca agaaagtgat tggtttacca tcaatatcga tctggtaggc
    36301 accgatatgc tgtgtgattc cgccggcttc gccgcttgtt acacgtgaat ggcgtaatgt
    36361 atccaataaa gttgttttcc catggtctac gtgtcccata atcgttacga ctggcggacg
    36421 tgagactaat ttatctggat cgacttcttc tgcctcgaag aatttatcga tatcagcaat
    36481 gtcaacttgg actttttctt gtggttccat gccatagtcc gtcgctaaca gttcaatcgt
    36541 atctttatcc agtgcttggt tttgattgac catgacacca agcataaata attttttaat
    36601 gatttctgct ggctcacgat gaattttttt cgcaatatct gctacgttca taccttcagt
    36661 atactctaat acatctggca attcacggaa tttgcgtggt ggtacagctg gtttagttga
    36721 ttgttgctgt ttgccttttt tacctttttt attataacga ttacggttat tattattaaa
    36781 tttgccgcga ttgttattgt ttggtttgtt gttattgtta gtacggtttt gattgccgcc
    36841 ttggctcgtt ccttgacgat tttggctgct ggtatttccc gtattatttt ggtttgttgt
    36901 tggttttttt ccttgattca cttgaccgct cccttgaccg cgatcttgat aactgcggtt
    36961 atttttattt ttttgttgat tgttcgttgt ttctttttta cgttgatcgt tcggctgttg
    37021 attggctggt tttctgcttg cttgttgtgc agcttgttgt ttcgtgcttg ggtttttgaa
    37081 cgcttgttgc aatttcttct catcattgct agtaatcgca cccatatggt ttttcacatc
    37141 gatgccaagt tgttgtgctt tttccacgac gtctttacta gattttttga gttcttttgc
    37201 taattcatag attcttttgt tgcccatgca atcaccttcc taaccttcaa ttagctcctt
    37261 ggtcttcttc gcaaatccgg catccattat tccgaatacc ttgcgaggtt ttccgatcat
    37321 ctgcgtgatt tctgcttcag aaaatagctc aaagcaagga acttcataat atgaactctt
    37381 atcttttatc ttttttcttg tattctcgct tgcatcggtt gccacaaaca ccaattttgc
    37441 tttttgtttg cggatttcag caatggtcag ttcttcaccc gtgattagtt ttcccgcgcg
    37501 catcgctaga ccgatgagat tcatggcttt ttgccgatta actgtattca ttttccaaat
    37561 aactctttac gtgctttttg gtgagtgaca tagtcaagaa gttcttgata aaactcatct
    37621 gttaatgttg tttcgagtac tcgatcgaga atttttttat cccaagcttg ttgtacttct
    37681 tccggctcaa gtgagacata cgctcctcgt ccaggcattt ttccagttgg atcgatcgat
    37741 acttcccctt cttttgaacg ggtgattcgg accatctctt ttttaggttt catttcacct
    37801 gaaaccacgg atttgcgtaa aggaattttc ctttgtttca tctctttgcc tccttactaa
    37861 agttaagctt ctggtttttc ttcgaccgtt tcattgttga atgcaattgt ttcatattca
    37921 tcgtctgtta aatctgactg aacgattgct tcatcatgca gttcttctgt ttctttttgt
    37981 tgttcttgat tttcataaaa ttccgtcatg tcagattctg atttgatatc gattttatgg
    38041 ttagtcaatt tagcagctaa acgtgcgttt tgtccgcgtt taccgattgc tagcgataat
    38101 tggtagtctg gaacgacaac tgtgcaggcc tttggatttg tctcatcgaa gatcacatcc
    38161 atgacttgtg caggattcaa tgcatttgca atgaatacag ctggatcttc attccattcg
    38221 acgatatcca tgttttcgcc ttttaattca ttgacgattg cttgaactcg ttgtcccttt
    38281 ggcccgacac atgtaccgac tgcatcgata tttggatcat ttgagcgaac tgccactttt
    38341 gaacgatcgc cagcttcacg ggcgatgctg acaatttcaa cgattccatc atagacttct
    38401 ggtacttctt gctcaaataa gcggcgcaat aggtctggat ggctgcggct aacaaatact
    38461 tgcggacctt tagacgtatt ttctactcgg gaaacataaa ctttgattcg atcatgtggt
    38521 tgataaaatt catttggcat ttgatcttgt ttagaaagaa ctgcctcaat tttaccaaga
    38581 ttgacataaa tataacgttt atcctggcgt tcgacgattc cttgcatgat gtctttttca
    38641 taagcactga attcgttata aataatcgtt ctttctgctt cacgtacacg ctgtaaaata
    38701 acttgtttag ccgtttgcgc agcgatccgc ccaaaatctt ttggtgttac ttcaaaacgg
    38761 atcgtatcac cgatctcata tgctggattg attaaaagtg catctttcaa tgagacttcc
    38821 aactgtgaat ccatcacttc ttccgttact tcttttaccg catagacatg gatctttcct
    38881 tttttctgat caaattccac ttcgacgttt tgtgcttggc catagtgacg tttgtatgca
    38941 gaaaccaatg ctgcttctaa agcatcgatc acgatttctt ttgagatccc tttttcagct
    39001 tctaaagcgt ctaacgcatt taacatttct ttactcattt tttctgattc ctctccgtga
    39061 ttaaaattgg atagctaagc gagcttttgc aatatttttt cggtcaaaag tcaattcttt
    39121 ttctcgtgtt tttatgcgta ttttcaatgt aagctgttca gcatcaaatg attgaagaaa
    39181 tccttcatat tgtttttcgc catctactgg ttggtataag gagacatgga cataatcacc
    39241 aagtgccttt tcatagtcgc tttctttttt caatggccgc tctgctcccg gggaggatac
    39301 ctccaggaaa taagcttgag gaatcggatc tggatctgct gcatcaagtt tttcactcag
    39361 tttctcactg acaaaggcgc attcttcgat atcgataccg ccttctttgt caataaatac
    39421 tcgtaagaac cagctttttc cttcttttac aaattcgact tcgacaagtt caaaattttg
    39481 ttcatctaaa atcggtgtca ccatttctgt gactgtttca acgacgctac tcaaaagttt
    39541 cgcctcctta aaaaattaag tgcgtaattc cattaaaaag agtgagcgaa aaatccgctc
    39601 actcacagtt agtatcatta cctataagaa ctataccata ctctgcttaa aattacaagc
    39661 agacaggaaa acagatgctt atagcatatc gaataacgat aattgatttt catctggtag
    39721 atctttcaat acgccattgt cgttcatata ttcgatcaat gtttttgaaa ctttaccgcg
    39781 ggtggcaaga tcttctttgg ataaaaatgg accgtctttt cttgcttcaa cgatttgttt
    39841 tgccacgttg gttcccaaac ttgggacagc tctaaatggt gcgatcaacg tatcaccttc
    39901 aataacaaag ttaacggcat ccgatttata caaatcaatc attccaaatt tgaatcctcg
    39961 ttccagcatt tcattggcta actccagcac tgtcagttga ttcttttctt ttacggaagc
    40021 atctaatcct ttgtccgtga tttctttcat tgcttgtttc acagcatctt ttcctttgca
    40081 catggagact agatcaaagt cgtctgcacg tacagaaaag tatgcacagt aatacaaaat
    40141 agggaaataa accttgaaat aagcgacacg aagagccatc aatacgtaag ctgcagcatg
    40201 ggctttcgga aacatatatt tgatttttga acaagaatcg atataccagt cgggcacatt
    40261 attttctttc atcgccgata gataggtttc tcgcaattca tcagggatct tgttccattg
    40321 tcctttacga acagtttcca tgattttaaa tgccatcccg ctatctaatc cagcatggat
    40381 caaataaacc ataatatcat cacgacagcc gattacttcc gccagtgtcg catctcctcg
    40441 tcgaatcaat tcttccgcat ttcctaacca tacgtctgta ccatgagata gtccggaaat
    40501 ttgcagtagt tctgcaaaag ttgtaggatg cgtttcttct agcatccctc gaacaaaacg
    40561 agtgccgaat tctggaatac ctaatgtccc tgttttggaa taaatttgtt cctgacttac
    40621 tccaagtact tcaggaccgg caaatatccg catcacttcc gggtcatccg tagggatcgt
    40681 ttgtggatcg atccctgata aatcttgaag catccgaata acagttgggt catcatgccc
    40741 tagaatatct aatttcaata cattatcgtg aatcgagtga aaatcaaaat gagtcgtttt
    40801 ccattccgaa ttttgatcgt ctgctggata ttggatcggc gtaaaatcat agacatccat
    40861 ataatcggga ataacgatga tcccccctgg atgctggccg gttgtccgtt tgactccagt
    40921 agcgcctttt gctaatctgt cgacttctgc acttcgaaac tgcagattat tgtccctttc
    40981 gtatcctttt acatagccat atgctgtttt gtcggcgact gtaccaatcg ttccggcacg
    41041 gtaaacatag tcttcgccaa acaatacttt cgtatagtta tgggcttctg cttgataatc
    41101 acctgagaag ttcaaatcaa tatcgggcac tttgtctcca tggaatccta aaaatgtctc
    41161 aaatggaata tcatgaccgt ctttgtttaa gcgtgcacca cattttggac attgtttttc
    41221 tggcatgtca aatccagaac catacgtacc atcttcaaaa aactcggaat attggcactc
    41281 tggacaataa taatgagggg ctaacggatt aacttcagtg attcctgtca tcgtcgcaac
    41341 aaagctagag ccaacagagc cacgtgaacc tactagatag ccatcttcat tacttttatg
    41401 cactagtttt tgggcgatca gataaataac cgagaagcca ttaccattaa tagaattcaa
    41461 ctcttttttt aatcgttttt gaatgatctc aggtaacgga tctccgtaca tttgttttgc
    41521 ttttgtgtaa ctcaattctg atatttcatc ttctgaacct ggaatcttcg gtgtataaag
    41581 ttcatctttg actggaatca cttcttcgca gatatctgcg attttattcg tattttctac
    41641 tacgatctct ttcgctgttt cttcccctaa aaagtgaaat gcagttagca tctcatcggt
    41701 tgttcggaaa tggacatccg gcaaactatg acgattcaac ggattcgctc cgcccataga
    41761 attgatcaaa atttttcggt aaatggcatc ttcttcgttc agataatgta cattacctgt
    41821 tgcaacaacg attttatcca aactttttcc gatttctacc aaattttgga taatttcttc
    41881 caaatcatgt tcatttttta ccaattcttg ctcgatcaaa ggcgcataga ccgcttttgg
    41941 cataacttca atataatcgt agaattttgc tcggtttctt gcctcttcta cccctttttg
    42001 catcatggct tcgaatattt ctcccttatc acaagctgag ccgatcaata gattttcacg
    42061 catctttttc aattgggagc gtggtattcg tgggacgcgt tcgaagtatt cgacattcga
    42121 cattgaaatc agtttgaaca aatctttcag tcctgcctga ttttttgcta aaatcgttac
    42181 atggaaaggt cgagcccttt tgtaagaatc tccttctccg atatgctcat ttagctgatc
    42241 atgataaagc atgttatgat tgtccattgc ctctttcaca aagatccatg ctaagtgacc
    42301 agttgcttca gcatcataga ttgctcggtg atgctgttcc aagctgacac caaatttttt
    42361 agataacaca cctaatccga aacgtttgaa ttgaggatac agatatctag ctaattccaa
    42421 cgtatcaatg actggattgg ccgcttcagg aataccatac cttgcgtagc tagtattcaa
    42481 gaaccccata tcaaaagccg cgttgtgggc taccaaaatt gtatcttttg aaaattcaag
    42541 gaacatccgc aatacttctt cttccgactt tgatcctcga accattccat ccgtgatacc
    42601 agtcagatct accgttgttc gtgacaaagg atgtcctgga tcgataaatt catcaaagct
    42661 ttcgatcaca tttcctttat acattttgac tgcggctagc tcgatgatcg tgtcatatac
    42721 tgcagacaat cctgtcgttt ccacgtcaaa tacgacatat gtggcttcac tcaatgcttc
    42781 atgtgcatca ttataagcaa ttgggacacc atcatctacg acattcgctt ccacgccgta
    42841 taagattttc acacctgctt tttttccagc actatgtgct tccggaaagg cttgcgcacc
    42901 accgtggtct gtaatggcga tagctcggtg tccccatttc cctgcttgtg ccacaagatc
    42961 agagatgctg tttgttgcat ccatcgtact catattgcta tgaacatgaa gctctactcg
    43021 tttttcccct tcaggagcat aatctttgcg aggtgtatgt ttgacttcta tgatatcttg
    43081 cgcattcatg accaaatcac ggacaaacgt atcttcttga atacttcctc gtacctttaa
    43141 ccagctaccg acactgatcg catcaaatac ttgttcatct ttttcgccgt tcgagaattt
    43201 tttgacgata aatgatgaag tataatctgt gattttcaaa gtcaagatct tgcgttttga
    43261 acgtagttct ctgacttctt tgtcgaatac gtacccctca agtgtgactc ttcgttcttc
    43321 ttcaacgata ctgatcattg gtgtcgttgg ttcatcggct ggaatatttc gtcctagctg
    43381 gatgtggatg ggtccttcaa gagctggcga ttgctctttt ctttcctttt tcttttgttc
    43441 gtggacaact agactttcag ctgcttgctt cataaaggct tctgcctgtt cttgtttgcg
    43501 ttcttcaaaa agtttcaata ctcgttccgc ttgctgctca tccacttctg gttcgatacg
    43561 aaattttggg aatccgtaac tgacgaacaa ctcttctact aatggcaagt attgttgctt
    43621 caaataagaa atagctcctg tactgtcgat tggcaagatg actttacgat cttttatcac
    43681 aggtacctgc gttttcaata cttgctgtgc tagtggtgta tcgcattgct gattttccaa
    43741 agcttgggcc cagtaatctt gcaagagctg ttcatcgaat gtctggtcat ctgctaagat
    43801 attcagtttg acttgtgcaa tatctttaaa agcgatagtc agatgctgag tcaatgaccg
    43861 atatagcata ataggcaaaa ttttggaaaa atgcagcgta aattcccata aacgcgattt
    43921 acgatggacc actacactat ccatttcacc agcagtaagc agtggatgat ttttttctgc
    43981 ttcctctagt tggatttgtt ccaacagttt ttcaaataaa tctcgttttt ctgacaaaga
    44041 tatacgccct ttctgatgag aaacaatgca attgatcgca tcttatcctc ttctttttca
    44101 gtacctttta gtatactcgt tttttctgag ttttacatta aaaaattgga actgcgattc
    44161 aaatcgcagt tccaatttta aaagcgaatc atcagattgt caaaaacagc tgattcagct
    44221 atttttattt tctgtgtttt aacgcttatt attcgccttg gttcaagagg attggtaaag
    44281 tattcaccaa ttcttcttta cgtacttcaa ccatttcgcc agttttcttg attttcactt
    44341 ctacgattcc atccactgct tttttaccga cagtgattct gattggacag ccaatcaaat
    44401 cagaatccgc gaatttcact cctgcgcgtt catttctgtc atcaaccagt acttcatagc
    44461 cagcttttgt catcgcttct tctagttcat tcgtcaggtt tgtttggtat tcgtctttta
    44521 gattcatttg gacgatatgc aaatcaaatg gcgcaattcc ttttggccag ttgattcctt
    44581 gttcatctga atgttgttct acgattgctg ataataaacg acttacaccg ataccataac
    44641 agcccataat cacaaatttt tctcgtccat tttcgtctag tacagttgct cccatagatt
    44701 cactgtaacg agtgccgatt ttgaagatat gtccgatttc gattcctcga gtaaaggcaa
    44761 gaacaccatt gttgtctggt gaaggatctc cttcttgtac aaaacgaaga tcttcataag
    44821 aaagtacagt gaaatcgcgt tctggattca catttttata gtggaatcct gtttcgttcg
    44881 ctccagtaat ggcattcgct aaatcttgga cataacggtc tgcatatact tttacgtcat
    44941 ctgaaacacc gactggtccg acagaaccaa actcagcacc tagatatttt tgtgcttctt
    45001 cttctgttgc ttcttctaaa aagtcagcag ataaaaagtt tttcagtttt acgtcattga
    45061 cttcatggtc tccgcgtacc aaaacaagga caggttgttc atccgcaatg aacaatacag
    45121 acttgatgat tttttgaggt tcaacagaaa agaaatctgc tacttcgtca attgatttta
    45181 cgttaggtgt agctactttc tccaattcaa gctgtgtttc atgcgatttt tttgatacat
    45241 agtagcttgt agccatctcc aagtttgcag cataatcact ttcagtcgaa taacagatcg
    45301 tatcctcccc gatttctgag atcgccatga attcttttga gtctttcccg cccattgcgc
    45361 caccgtctcc gataatcgag cgaaattcta agccacaacg cttgaatact tcggtgtagg
    45421 ctttttcgta atctttatat gtctcgtcca aactttcttc cgttgcatgg aaagaatacg
    45481 catctttcat gataaactct cttccgcgaa gcaaaccgaa gcgaggtcgt ttttcgtcac
    45541 gatatttagg ttggatttga taaagattta aaggtaattt cttatatgaa ttgatttcat
    45601 tacgcatcaa atcagtaaaa gtttcttcgt gagttggtcc aaggatcatt tttcgatcat
    45661 tgcggtcttt gaaacgatac aagtttggtc catatgtttc gtaacgcccg gattcttccc
    45721 aaagttctgc tggcaagatg gcaggcatca gcatttctac cgctccgatt ttttcaaatt
    45781 cttcccgcat aatgcgtttc agtttttcca atacacgatt tgctaatggc agatatgaat
    45841 aaatacccgc tgatacttgg cggatatatc cagctcttag caagatttga tggcttaata
    45901 cttctgcatc atttggaact tcgcgtaatg ttggaatcaa catttttgat tgtctcattc
    45961 tatatactcc tttatttcct caaaatagtt atcgtttgtt attataccct atttgtcaac
    46021 tttttctaga aaaagaatcg ttgaatatcg ttccatgtaa ctagcaccat caacaacatt
    46081 aaaaatccaa agccagctaa tgtcaatatt ccttcttttt cttgacttaa tggtttcccg
    46141 cgaatccctt caaaaatatt caagactaat ttcccgccat ctaaggcagg aatcggaagc
    46201 agattgacga ttccgagatt cattgaaaga agcgccatca aactaataac agttgttaca
    46261 ccttgatttg ctgcttctga agacaattgg tacatcatga caggtccgcc taatttatct
    46321 aaactgaaac ctgtaaatag tgatcctaag gctttgaaaa tttccaatga accgctgaaa
    46381 gcttgacgcg tccctccaat gatcttatcc ataaaacctg tattcattgg ggcttttata
    46441 ccaagttggc caactttttc gccatttgac tctacagatt tcggtgtcac gtcgacagat
    46501 tgcacctgac cttctcgttc gatcttaaag tctaatgttt tatccggatt tttcgtaatg
    46561 actgttgtca gatcattcca tgaatggatt tcttttccgt ccacactgac tacctcatca
    46621 ttttctttta agcctgcttc tgccgcagct ccattaggca tgatctctcc tacgcgatta
    46681 gtgttcgtca cttgaacacc accttgcata aatgccagaa tgatgaataa caggattgcc
    46741 aaaataaagt tattcatggg tccagcaaag ttggtcagca tacgctgcca caatttagcc
    46801 gattggaact gtacgtcttt tggcgcaatt ctgatttctg ttccgtcgtt ttcaataatc
    46861 gtcgcatcgt gatcaacagg gtaggttact acttctgttt cgtctccatt cacataacca
    46921 gtgatagtca gctcatcttc taaatcataa cggctcaatt ccatcgggat agcatttgtc
    46981 aattggattt tcttacttaa atttatcttc tctacgatgc cgtcagaatt tagtaaaaga
    47041 gaaagaggca ttcctggtgc catttctgtt tcatcatccc cattgcctgc cattcgaaca
    47101 taaccgccaa taggtaatag gcgaagcgta tatgttgtcc cgtcttttgc ttgatgccca
    47161 taaattttcg gacccatacc gatagcaaat tcgcgaacga ggattcctga tcgtttcgca
    47221 aagaagaaat gaccaaactc atgaacaatc actaatatac caaaaacgat gataaatgtc
    47281 agaatcgttt tcatagcttt tttctccttt acttgttttt tgtgtttttt ataaaacaac
    47341 gataaaacac tataatttta ccatagtata ccaaagacac caatagtatc aatataatga
    47401 aaaataaaaa cctgcgtctt ttatgaaatt cacaaagaaa cgcaggtata cttactaaat
    47461 aatgccaaat aaatgcatga taggaaatac aaacagcaaa ctgtcgaaac ggtctaagat
    47521 tccaccatgg cctggtaaga tatttcccga gtctttcaca tcataatgac gtttgattgc
    47581 agattcgacc aaatcaccaa attgtccgac tgctgaaaaa ataatcgtca tcagaagcat
    47641 gacaaacata ccatgattaa atagttcttt tgctgggtat agcaataaat aaagaaatgc
    47701 gactacaaca gcactaccaa taccaccgag cgcaccttca atcgttttgt tgggcgaaat
    47761 atcaggactt aacttatgct gaccataacg tcgaccaacc atatatgctc cgatatcagt
    47821 tgcccaaaca ataaatagac caaatatcaa aacagccaag ctttctgttc gtgcattgac
    47881 aaaattctgg aaacctattc ccacatacaa gctgacaagc acaggaaaac ctgcttcatc
    47941 aatcgtatac gtatttttag aaataactga tgttcctaaa agaatcataa ctataagata
    48001 aaataacata aatgtactta cattctctgg aagaaagaaa aaccatcttt cttttggcaa
    48061 aacaagtaac actgcaccaa cggcggataa aactccttca aaacttaaga gtgtcaatcc
    48121 tttcatccga aacagctcgt aaactcctat tactgctaag attgctgctg taagctcaac
    48181 cgctatgcct ccgatccata taatcggaat aaacaagact agcgccacgg ctgctgtgac
    48241 cacacgttgt ttcatgactg atcccctttc tcatcttctg ttttttttac accgccgaat
    48301 cgacggtctc gattttgata agaggcgatt gcttcttcaa gatgcgcacc atcaaaatca
    48361 ggccaaagcg cttttgtaaa atacagctca ctatatgcga tctgccataa cagaaaatta
    48421 ctaattcgct cttctccact tgtacggatc atcagctcag gatcttgtaa ctctttaggc
    48481 aagaaacctg tcattaaatg cttagcaatc aattcatcat cgatttcttc tgcgtgtatt
    48541 tctccttttg ctacttcttc ggcaatttct tggacagcag tcacgatctc tgctctgctt
    48601 ccataattca aagcaaaatt caataccatt ccagtattgt tttttgtttg ctcaattgca
    48661 cgtcttacag catcttgcgt atgttctggc aatacgtttt cataacccat gacatgaact
    48721 ttgacatttt ctttaatcaa ttctggtacg aacgtatcaa agaagtcgac aggtagttgc
    48781 atgagaaaac ttacttcatc ttttggtcgc ttccagtttt cagtcgaaaa ggcataaagc
    48841 gtcaacactt tcactccaag ccttgatgct ttttttgtga ctttctttac tgtttccatg
    48901 ccttctttat ggccagcaac tcgtggcaaa cgacggtttt gcgcccaacg accattgccg
    48961 tccatgatga tggcaatgtg ctgaggaatt ggtccatcgg tattaaattg aaattcgctt
    49021 ttttcttgaa tatatttgtt tttttgcgga aaaaaacgta acattctttt tcctcctata
    49081 cttaaaagat tcccactatc ttaagtatta tagcaatatc taactgtttt tcctatgaaa
    49141 tcattgtttt tttatttaaa aactgaataa ttttttcttt ttttaatttt taaataaaag
    49201 aaatataaat aaaaacagag gaagcggaat gatccgcccc tctgttttta tgattttatt
    49261 aaacttccaa taattctttt tctttatcag cagcgatctt atctacttct ttgatgctgt
    49321 tatctgtcaa tgtttgtacg tctttttcta atccgcgcaa atcatcttcg gtaatatcac
    49381 catttttttg ttgtttttta tattcatcga tcgcatcacg acggatgtta cgaatcgcga
    49441 tttttgcatt ttctgcttct tttttaacat ctttagctaa ttcttttctg cgttcttctg
    49501 tcagttgcgg gataactaag cgaatgacat ttccatcatt ggttggactg attccgatat
    49561 cacttgccat aatagctttt tcaacatctt gaagaatgct cttgtcaaaa ggtgtgatca
    49621 ttaaaacacg tgcttctgga atttggattg atgccatttg gttcaatggt gttggcgcac
    49681 cgtagtagtt cacagtaata cggtccaaaa ggctagcgtt cgcacggcct gcgcggattt
    49741 gcccaagttc acgttgaaga ttttgtgctg cttttttcat tttttctttt gcttctgtca
    49801 taattgcatc tgccattttt atttccccct tacagttgtt ccgatatttt cgcctaagat
    49861 tgcacggcga atatttccgt gttcatttaa attgaagaca agcagtggaa tatcattatc
    49921 catgcttagt gaacttgcag ttgaatccat gacttgtaat cctttggcaa taacttccag
    49981 atgagtcagt tcttcaaatt ttactgcatt tgcatctact ttcggatcag cagaataaac
    50041 accgtctaca ttgtttttag ccatcaggat aacatctgcg ccgatttctg ccgcgcgtaa
    50101 tgctgctgtt gtgtctgtcg agaagtacgg gttgccggta ccgcctgcaa agataacgat
    50161 ccgtcctttt tctaaatgac gttctgcttt acggcgaata tatggctctg cgatttgacg
    50221 catttcaatc gaagtttgca cgcgtgtcgg tacacccacg ttttccaacg tatcctgtaa
    50281 agctaaggca ttcataactg tagctaacat acccatgtaa tcagcttgag cacgttccat
    50341 gcccatttgt gctccgattt gtccgcgcca gatatttccg ccgcccacaa cgattgccat
    50401 ttcaacgccc agctcgtgaa cttctttgat ttcttggatg atttctttga ttactggtgg
    50461 tttgattcca aatcctgcgt ccccagctaa agcttctcca ctcaatttta agactacacg
    50521 ctgatatttc ggtgtgacca tgttcattcc tccaatattt tctattgcca ttttaccata
    50581 cttagatgat ttcgacactc taagactggt ttttcttgtt ttgcttaaaa aaagggagcg
    50641 cacaaaccgt gcgttcccgt ctgttattca acagaattat tttttcactt ggctcataac
    50701 ttcttctaca aagttatctt cgcgtttttc gataccttcg ccaacttcga aacgtacgaa
    50761 tgttttaaca gttgcgcctt ttgatgcaac gtatttttca acagtcatat caggatcttt
    50821 aacgaatggt tggtccacca aagcgatttc tgctttgaat ttcttcaagc gtccttctac
    50881 cattttttca acgatattcg ctggtttgcc ttcgttcaat gcttgttctg taagaacagt
    50941 tttttcatgt tctaattcag cttctggaat ttgtgattcg tttacataac gaggattgat
    51001 agctgctacg tgcatagcta cgtctcttgc aactgtttcg tcagttgttc catctagaac
    51061 agtcaatacg gcaatacgtc cgcccatatg caagtatcca ccaaatgcag cattgtcgtc
    51121 tttttctaca acttcaaagc gacggaagct gattttttct ccgataactt gagttgcttc
    51181 gatcaagtca gattcaattg tacctttatc tgttttgatt ttcattgcag cttccatgtc
    51241 tgctggtttg ttttcagcaa caagttctgc aatttctttt actaaatctt ggaacatttc
    51301 gtttttagaa acaaagtctg tttctgagtt tacttcaacg attgctgcag tgttaccttt
    51361 cacagcaact gaagccaatc cttcagctgc aatgcggtca tttttcttcg cagcctttgc
    51421 cattcctttt tcacgtaaaa gatcaactgc tttttccatg tcgccttcta cttcaactaa
    51481 tgcttttttc gcatccatca ttcctacgcc agtcatttcg cgtagttctt ttaccatttt
    51541 agctgtaacg tctgccatgt ttaactcctc ctgtgtgttt ttctttttaa aaaaagctgc
    51601 ttcaaaggag agtgaggctt gtcgcccagc ctttgaaaca gctccatcat tcaaaattat
    51661 tctgctgaag aattgtcgcc ttcaacaaca tctacgattt cttcgattga tgttgctgtg
    51721 ttttcttctg tgaaatcttc ttcaactact tgatcttcac cttggtttcc ttcgatgaaa
    51781 gcatcagcca tttttgaagt aatcaattta acggcacgaa ttgcatcgtc gtttgaaggg
    51841 attactacgt cgatttcatc tggatcgcag tttgtatcaa ccatagctac gattgggata
    51901 tttaatttgt gtgcttcttg aacagcaata cgttctttac gtgggtcaac gatgtacatt
    51961 acatctggga ttcttggcat atcagcgata ccgcctaaga atttttcaag acgttcacgt
    52021 tctttgttca aaccagcaac ttctttttta ggtagaactt caaaagttcc atcttcttcc
    52081 attgcattga tttgtttcaa acggctgata cgtttttgga tagtatccca gtttgtcaat
    52141 gttccgccta accaacgatg gttaacgaag tattgtcctg cacgagttgc ttcttctttg
    52201 attgcttctt gtgcttgttt ttttgtacct acgaataatg ctacgccgcc ttcttcagca
    52261 acgctcttca tgtaatcata agctgcatct actaatttaa ctgttttttg caagtcaatg
    52321 atgtagattc cgtttctttc tgtgaagata tatttcttca tttttggatt ccagcgacga
    52381 gtttggtgac caaagtgtac gccggcttct agtaattgtt tcatagaaat tactgccatg
    52441 tttgtttcct ccgatttggt tttatttttc ctcttcttat cttctacctt gccggcaaac
    52501 tttttcaagc acctaccgac aatccaataa gaatgtggat ttgctgatgc ataaagcacc
    52561 ctcagctatt atacagacaa aagatccgta tcgcaagagc aaatatactt ttctgctcaa
    52621 cattcaatag tttacctgaa agataaaaag aattcaagaa aaacagtaga tttctctttg
    52681 tttctttatt atcctttttc cataaaataa ttttaggtat aaaagacgaa tattattggg
    52741 caatccttct tttttttgtt atgatacatg tgaaatcttt cgtaaaggag aaagaaaatg
    52801 cgcaaagctc aaagacattt gctgattaaa caagtcattg aagaattccc gatccgtacg
    52861 caagaagaac tattaaacaa acttgggcat tatggcgtta ccgccacgca ggcaacgatt
    52921 tctcgagata tccgtgatct aaaaatcgtg aaggcacctg atgaaaatgg cgtttcccgc
    52981 ttcgtattgt ttcgcgaaaa aggaactcct gagactagga ctgaggaaga ggatcggctg
    53041 gttcaaatga ttgaagacat tgtattgaaa gtcgaacgag tccacttttt gacgatcgtc
    53101 aataccttgc cagacaatgc tcatttattt gcatctgttt tagatgagat caaacctccc
    53161 tctattgtca gtacaattgc tggattcgat acgatcatgg tcatctcgga aaatgaggag
    53221 gacgcaaaac gagtagaaga atttcttcac catccaactg aagtatcact tttttaatca
    53281 gagcacgtat tcctaatatg gaatgcgtgt ttttttattt tcaatatttt ccttattgaa
    53341 taaaccttta cactctttac aaaaatacat cattttttat tcaaattttt caacaccttg
    53401 attgaatcac aataatcatc atttatattg gatgttaaca agagcagctt cttgctcttt
    53461 gtgtatttca aaaaagaaat gaaaggaaat catatgtata aattattaac ttctggacca
    53521 ttgacgactt ctgaaacagt gaaaaatgct atgctgatcg atcattgtac ttgggatcaa
    53581 gaatacaaag aaattacaca atggataaga aaaaaattat tggatcttgc tcaagtatcg
    53641 gaaggaatat acacaacggt cttaatgcaa ggtagcagct ccttcggggt agaatcggta
    53701 ttaagttctg tgatcaggcc agaagatact gtactgattt gttcaaacgg cgcatataga
    53761 caacgaatga tcaacatgtg cgaatgtctg aaactgaact ataccgttta tgaggtatcg
    53821 gaacatcaaa tcctccaagc tcatgtgatt acacagctga ttgaagagaa tccgtctatc
    53881 tccgcactag caatggtcca tagcgagact acttccggta ttttgaataa tttggaagag
    53941 attgctgctg tcacacaaga aagagatctt ttgtttatag tggacgcgat gtcaagcttt
    54001 ggtgggatac cgatttgtgt agccgaacta gggattgatt ttttgatttc cagctcaaac
    54061 aaatgtattc aaggtgttcc aggcttttct tttgtacttg ctaataaagc ggaactggaa
    54121 aaacgaaaaa atgttagccg aagtttgtca cttgatctat atgaccagta ccgcgtgatg
    54181 gaaaacgaga atggcaaatg gcgtttcact tcccctaccc atacggtttt ggcttttcaa
    54241 caagcgctga aggaactaga ggcagaagga ggaatcgaaa ctcgatattc acgttatctc
    54301 gccaataatc atgtgctacg acaaaaaatg acagagatgg ggttccagcc tttcattcaa
    54361 gaatatcagg ggccattcat cacctctttt ctttacccta aggactggcg atttgatttt
    54421 aatcattttt atcagtattt aaagcaaaat ggatttgtga tctatcccgg gaaaatcagc
    54481 gatcatgaat gttttcgtat cggaaatatt ggcgagatct atccggaaga tattttggaa
    54541 ctgacagcaa ttatcaaaga ctataaggag aacgttaatg attaaaactg taatttttga
    54601 ttgggcagga acaactgtgg actttggctg tatggctcct gtccacgctt ttagaaatgc
    54661 ttttctagaa aaaggaatcc aactgactga caaagaaatc cgctaaccga tgggaaaatt
    54721 aaaatgggat catatccaac agcttctttc cctcccttct gtcaaaaaac aatggatagc
    54781 tatttatgga caactacctc aggaaaaaga ggtggaggaa ttgtatcaac aatttgaaca
    54841 ttatctgttt aaagatttgg tcaagcattc taccttgaaa cccgacacat tggaaacgat
    54901 cgaacggttg agaaacgctg ggatcaatat tggttccacg aatggattta atgctcctat
    54961 gatgacaatc gtagcagaaa ccgcaaaaaa agaaaggtat tcaccagact tcatggcaac
    55021 ttttgaagac gtcgaagggt atggtcgacc gtttccttat atgatccata aaaacatgca
    55081 gtacttcaaa aacaagtcgg ttgatgaagt aatcaaagtc ggagatacgg tctcagatat
    55141 ccaggaaggg aaaaatgccg gagtgttgac agtaggtgta attgaaggta gttcgctaat
    55201 ggggatttct tatgatgagt accaaaaatt agagatgggg aaaaagatcg tttaaaacag
    55261 tctgttgctc ttagattcca acaagccggc gctgatattt gtgtaaacaa tttaaaagag
    55321 ttaacagaat acattttgta cgctgacatg aatccagaat gacttttata caaaataaga
    55381 ggttgtgaaa aagctgtcct gtatcaagta ataaaaacag ccaagcaaaa atagctcctc
    55441 atatttttcg tttggttagg cttattaccg cagatgcaag cttttgaaca ccgtttattc
    55501 gaaaaaaaaa agggagctgt gacacgactt ttgtcacagt ccccttattt gcaaacaaac
    55561 agtgtttaag agacaacctc tccactaaac ggtgttcatt cagctgactc tcggtatttg
    55621 ctcaaaaaac gataaaattt gaaaagctat tttctctttt gtttctctaa tactcggatc
    55681 agaacgctga tttcacattc tctttttctt acatcttatc tggtgcatga agtcctagca
    55741 aacgaaggtc ttctttcaat aatacagtca ctgcataaac tagagctaag cgtgcttctt
    55801 tttgttcatc atcagctaaa atcttcgtat gagcatagta tttgttgaat gcttgtgcta
    55861 atttgattgc atgtttcgca atcactgacg gttcgtattt ttccccagca gacaagaccg
    55921 tttcagggta tttttgaact aatttaacca cttcccagct ggtatcgtca ttcaatgcat
    55981 agtctgctgt ttctgaaggg acaaatcctg ctttttccaa caggctgact gcacgagcat
    56041 gtgtatattg cacataaggt ccagtttctc cttcaaatcg aacaacttct tccaggttaa
    56101 agtcaaatgt attcagtcga tcgtttttca aatcgtggaa aatgactgcc ccaaccccaa
    56161 cttgtttagc tacagcatct ttgttttcca aatcagggtt tttctcgctg atttgttctt
    56221 tagcagattg gattgcttca tttaatactt cttctaataa gacgatcttt cctttacgag
    56281 ttgataattt tttaccacct tgcgtgatca aaccaaatgg aatatggtgc atgtcgtcag
    56341 accagtcaaa gcccatttcc ttcaagacag ctttcaactg tttaaaatga tagctttgtt
    56401 cattccctac tacatataga gattgtttga agtcgtaagt acgtttacgg tacaatgcag
    56461 cagctaagtc acgtgtaatg tatagtgtcg caccgtctga cttcttaatc aacgctggat
    56521 tcaggtcata agcagatagg tcaacgatct ctgcaccttt atcctcgttc agcaaatgtt
    56581 tttcttctaa aagtttgacg atttcatcca tcttgtcatt gtagaaagct tcaccgttca
    56641 acgaatcgaa acgtacttcc agcagatcat agattttatt gaattctttc atcgattcat
    56701 cacggaacca ttgccataat tgaatagcct ctttatcgcc ttcttccaga cgtttgaacc
    56761 aagcacgagc ttcttcattt aattctggtt ctgtttcagc tacttcatgg aattggacgt
    56821 ataaacgaag caattcattg attggttctg ctttaacagc ttcttctgta ccccattttt
    56881 tgtaagcgac gatcagtttt ccaaactgtg ttccccagtc acctaaatgg ttgatgcgga
    56941 ttggctgata accgattttt tccataatga aaccgatcga attaccgata actgtcgaac
    57001 gcaaatgtcc cattgagatt ggtttggcaa tattaggaga agacatgtcg attggtactg
    57061 ttccttgatt cccgatgttg ctatccccat aatgttcttt ttctttcact actgtttgca
    57121 aaactttttt gctgataagt tctttattca tgaaaaagtt caagtaaggt ccgacaactt
    57181 cgattttttc aaagttggca gaatcgattt tttctgctaa atctgcagcg atttgctgtg
    57241 gcgcttttcg gtaaactttt gctaatgaaa aggctggaaa tgcaacatct ccgtgttcag
    57301 ctgattttgg attttctagt aattgctcga cttgttccag tgttaaatca tctttgacag
    57361 cgtcatagac agcttttgcg acaagatctt tattattcat ctttattcct cctaaagtgt
    57421 tcccttgatt gttaaacaaa aaaaatctct agcgacggca tacttagtat gccatcacta
    57481 gagacgagat ttcccgcggt accactccaa ttgtcctaaa aaaggaccag ctccatctga
    57541 tatcggtaga cgaccgtctg tttaaaacag aattctccaa gtgcgcttcg ttgtatcttc
    57601 ttcattcggc ttccaccact tccgaattcg ctagccaaga atgatacaag tactctcttg
    57661 ttcaacaaat cttagtctta ttaaactttc ttgaattata tcagaaaaaa aaacgaaagg
    57721 ctagtcgttt cataaaaaaa caatccagat ggcctaaagg agaagaaata ccacctggat
    57781 agctataaat catttcgtaa atacgaaaga cttaacaaat taatcagcta cgataatcgt
    57841 tccttcttca gaagctaaaa gattctcgat attttctaaa gaagtgatga ttgccttagc
    57901 gtttggtttt gcttcaacaa atgcaatagc tgcttctact ttcggaagca tgcttcctgg
    57961 agcgaattgc ttttcatcaa tgtattgttt catttctgaa acagtaacag tttctaattt
    58021 cttttgatct ggtttttggt aattgacata cacattgtct actcctgtca atacgatcag
    58081 caaatccgca tcgatgattt cggctaattt ttctgaagca aaatctttat cgattacggc
    58141 ttctcgtcct tctaatccag tagctgtttc tacaacagga atcccaccgc caccaacaga
    58201 gactgtgata actccttgat cgaccagcgt ttcgatgaca cgtgcttctt taatcgagat
    58261 gggtttaggg gaagcgacta cttttctcca tccacgtcca gcatcttctt tgaatgtcac
    58321 agtggagtca gcattcattt gttctttggc ttcttcttcc gtgtagaatg gaccgactgg
    58381 tttacttgga tttttgaatg aaggatcatt ttcatccaca ataacttgag tgactaaaga
    58441 aaccacatct ttatcgatcc ctttttcctt cagtacttcg cccatggcgt tttgtaacca
    58501 gtaaccgata gatccttctg tcattgcaac acatgtatct aaaggcattg ccggtgtttt
    58561 ctcagaatca gcagcttgct gctgaatcaa taggttaccg acttgcggac catttccgtg
    58621 ggagatgatc aattcatctc cttgttcgat aaatttcact aaatactttg ctgtttccat
    58681 taacgcttct tgttgggctt ttgcacttgc atccgtagac aagatggcat tgccccctaa
    58741 agcgacaact acttttcgtt tggccatttc attcgtcctt tcttcagttc taccgaattt
    58801 tctagataac aaaacgagcc agcgttttgt gattttccct caatgctgac tcgttttttc
    58861 gtgagatgaa tgtggttatg cttaaacgcg agggataaac aagttaccta atgttgctgc
    58921 catgatcgct ttgattgagt gcatacgatt ttctgcttgg tcaaattgac gagcatattt
    58981 gctgcggaag acttcatctg ttacttccat ttcagtgatg ccaaagcgtt ctttcatttg
    59041 ttcaccgtaa acagtgtttg tatcatggaa agctggcaag cagtgcaaga agatcaaacg
    59101 atctgtgttg tgtgtttttt ctaccatttc catattgatt tggtaaggtt tcaacaattt
    59161 gatacgttct tcgaatttat cttcttcacc cattgatacc catacatcag aataaaggac
    59221 gtctgctccg tctacacctt tatcaacatc gtcggtaatc atcaattgtg caccggattt
    59281 ttcagcaaag ccttctgcca ttttgacgat ttcttcttca ggttgtaatt cttttggtgc
    59341 aacgatacgc atattcgctc ctaaaattgc acctgtgact aataaagagt tagccatatt
    59401 gtttcgacca tctccgcagt aagcaacagt gataccttct actgttccaa agttttcttg
    59461 gatagttaaa aagtcagcga tcatttgtgt tggatgccat tcatcagtca agccattcca
    59521 aactggaaca ccagagaatt ctgctagttc ctctaccatt ttttgactga atccacggaa
    59581 ttcgattccg tcaaacatac gtcctagtac tttagctgta tcttctgtgg attctttttt
    59641 acctaattgg atatcatttg cacctagata ttcaggatgt gcacctagat cgatcgctgc
    59701 agtagtaaat gcagaacgag tacgtgtaga tgttttttca aataaaagcg caatattttt
    59761 tccttctaga tagtgatgtg ggataccacg ttttttcaag tctttcaagt gttctgaaaa
    59821 atcgatcaaa tattgtaatt cttcttttgt aaagtctttt tctgctaata agcttcttcc
    59881 ttggaatact gattctttca tattaaacat tctcctttag attgttttta tttaagatta
    59941 aagaggaaat cccgacggca gctgacagta agactgccgt caggaaacaa attacttcaa
    60001 gtcttcacgg acaagtggtt ggctcatgca gcgtggacca ccacgacctc gtgacaattc
    60061 acttgaattg atttctaaca ctttgatgcc atagctacga agcaattcgt tcgatacata
    60121 atttcggtta taagtgacta caacacctgg agcgattgcc aatgtgtttg atccatcatt
    60181 ccattgttct cgaggtgcaa cgatctcatc tccattacca gttgggatca gtacaagatc
    60241 atctaatcca agagcagctt tcatcgtttc gtgtaagtta tctgaatgag taatcttgat
    60301 atcatcacca tctggttcga ttgtaaagac atccatctta ccgtctttac tttgaattgc
    60361 tggatggata gtgaatttat cgtgatctac cattgtaaat acggtatcca aatgcatcat
    60421 tgcacggttg ttcggaattt tgattgccaa cactttttca aatcctgaat tttttgcgaa
    60481 taggtggcgt gctaattttt ctaaagcttt cgcattagtt cgttgagaaa tcccaacagc
    60541 tactacttta tcgcttaaga tcaattcgtc tccgccttcg atatgatctg gattttcacg
    60601 atccaaccat acttcgattc ctttatttgc aaatcttgga tgatgtttca aaatatattc
    60661 tgtaaacatc gattcacgac gacgtgcttc aaaagtcatc ttattgactg tcatcccatt
    60721 tcccattgat gcggaagggt cgcgtgtaaa gtacaagttt ggcattgggt ccatgtaaaa
    60781 tggatagtca tcgtctgctg acagatcata tagactgcta gaacgtactt cgatatcttt
    60841 tgtacgaacc ccagccatga ttttatctac catttcttgc gtttccattg atagaaggaa
    60901 ctcatgaaga ccctctctta cagcattcga tgcaatatga gattcatcca acattttatt
    60961 caagaattgt tctttgacat tgcctgcgtc aatcgcttct gccgctaatt tttccaagta
    61021 aagagtctcg acgccttcat tttgcaatgt cttcgcaaag ttgtcatgtt cttcttgagc
    61081 aatcggaaga tatggaatat catcgaacaa cagacgatcc ataatatctg gtgtcaaatt
    61141 ttccacttct tgtccaggcc gtttcagtaa aactgtcttt aatttcccta tttcagagaa
    61201 aacgtgaata ggtttatcca tgttgtgttg cctccttctt tttgattaca tgtataggat
    61261 atcctccttt tgtaatcact ttcataattt tgtctcattc aaaatgagac attcctcaca
    61321 ttaatattcg ataattaaat aa
//
LOCUS       DACGDM010000008        60192 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.008, whole genome shotgun sequence.
ACCESSION   DACGDM010000008 DACGDM010000000
VERSION     DACGDM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.008"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(114..473)
                     /gene="rplT"
                     /locus_tag="IXR05_000561"
     CDS             complement(114..473)
                     /gene="rplT"
                     /locus_tag="IXR05_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAQ4259106.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(526..726)
                     /gene="rpmI"
                     /locus_tag="IXR05_000562"
     CDS             complement(526..726)
                     /gene="rpmI"
                     /locus_tag="IXR05_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAQ4259107.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(798..1322)
                     /gene="infC"
                     /locus_tag="IXR05_000563"
     CDS             complement(798..1322)
                     /gene="infC"
                     /locus_tag="IXR05_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAQ4259108.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            1642..2274
                     /locus_tag="IXR05_000564"
     CDS             1642..2274
                     /locus_tag="IXR05_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4259109.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2276..3181)
                     /locus_tag="IXR05_000565"
     CDS             complement(2276..3181)
                     /locus_tag="IXR05_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4259110.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(3266..3919)
                     /locus_tag="IXR05_000566"
     CDS             complement(3266..3919)
                     /locus_tag="IXR05_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4259111.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            4241..5185
                     /gene="mvk"
                     /locus_tag="IXR05_000567"
     CDS             4241..5185
                     /gene="mvk"
                     /locus_tag="IXR05_000567"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAQ4259112.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5178..6155
                     /gene="mvaD"
                     /locus_tag="IXR05_000568"
     CDS             5178..6155
                     /gene="mvaD"
                     /locus_tag="IXR05_000568"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAQ4259113.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6168..7253
                     /locus_tag="IXR05_000569"
     CDS             6168..7253
                     /locus_tag="IXR05_000569"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAQ4259114.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7250..8314
                     /locus_tag="IXR05_000570"
     CDS             7250..8314
                     /locus_tag="IXR05_000570"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAQ4259115.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(8563..9366)
                     /locus_tag="IXR05_000571"
     CDS             complement(8563..9366)
                     /locus_tag="IXR05_000571"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAQ4259116.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9386..10228)
                     /gene="kduI"
                     /locus_tag="IXR05_000572"
     CDS             complement(9386..10228)
                     /gene="kduI"
                     /locus_tag="IXR05_000572"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAQ4259117.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(10244..11251)
                     /locus_tag="IXR05_000573"
     CDS             complement(10244..11251)
                     /locus_tag="IXR05_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAQ4259118.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(11258..11902)
                     /locus_tag="IXR05_000574"
     CDS             complement(11258..11902)
                     /locus_tag="IXR05_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4259119.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(12002..12760)
                     /locus_tag="IXR05_000575"
     CDS             complement(12002..12760)
                     /locus_tag="IXR05_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAQ4259120.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(12887..14038)
                     /gene="fucO"
                     /locus_tag="IXR05_000576"
     CDS             complement(12887..14038)
                     /gene="fucO"
                     /locus_tag="IXR05_000576"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAQ4259121.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(14120..14431)
                     /gene="rhaM"
                     /locus_tag="IXR05_000577"
     CDS             complement(14120..14431)
                     /gene="rhaM"
                     /locus_tag="IXR05_000577"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAQ4259122.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(14433..15278)
                     /gene="rhaD"
                     /locus_tag="IXR05_000578"
     CDS             complement(14433..15278)
                     /gene="rhaD"
                     /locus_tag="IXR05_000578"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAQ4259123.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(15292..16548)
                     /gene="rhaA"
                     /locus_tag="IXR05_000579"
     CDS             complement(15292..16548)
                     /gene="rhaA"
                     /locus_tag="IXR05_000579"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAQ4259124.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(16545..18005)
                     /gene="rhaB"
                     /locus_tag="IXR05_000580"
     CDS             complement(16545..18005)
                     /gene="rhaB"
                     /locus_tag="IXR05_000580"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAQ4259125.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            18158..19027
                     /locus_tag="IXR05_000581"
     CDS             18158..19027
                     /locus_tag="IXR05_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4259126.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(19153..20052)
                     /locus_tag="IXR05_000582"
     CDS             complement(19153..20052)
                     /locus_tag="IXR05_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4259127.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(20217..21041)
                     /locus_tag="IXR05_000583"
     CDS             complement(20217..21041)
                     /locus_tag="IXR05_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4259128.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(21052..22347)
                     /locus_tag="IXR05_000584"
     CDS             complement(21052..22347)
                     /locus_tag="IXR05_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAQ4259129.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(22363..22842)
                     /locus_tag="IXR05_000585"
     CDS             complement(22363..22842)
                     /locus_tag="IXR05_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAQ4259130.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(22848..23876)
                     /locus_tag="IXR05_000586"
     CDS             complement(22848..23876)
                     /locus_tag="IXR05_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAQ4259131.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(23893..24999)
                     /locus_tag="IXR05_000587"
     CDS             complement(23893..24999)
                     /locus_tag="IXR05_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4259132.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(25228..27825)
                     /gene="adhE"
                     /locus_tag="IXR05_000588"
                     /gene_synonym="adhC"
     CDS             complement(25228..27825)
                     /gene="adhE"
                     /locus_tag="IXR05_000588"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAQ4259133.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(28130..28510)
                     /gene="yajC"
                     /locus_tag="IXR05_000589"
     CDS             complement(28130..28510)
                     /gene="yajC"
                     /locus_tag="IXR05_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAQ4259134.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(28607..29752)
                     /gene="tgt"
                     /locus_tag="IXR05_000590"
     CDS             complement(28607..29752)
                     /gene="tgt"
                     /locus_tag="IXR05_000590"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAQ4259135.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            29970..30668
                     /locus_tag="IXR05_000591"
     CDS             29970..30668
                     /locus_tag="IXR05_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4259136.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(30836..33475)
                     /locus_tag="IXR05_000592"
     CDS             complement(30836..33475)
                     /locus_tag="IXR05_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4259137.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(34094..35125)
                     /gene="queA"
                     /locus_tag="IXR05_000593"
     CDS             complement(34094..35125)
                     /gene="queA"
                     /locus_tag="IXR05_000593"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAQ4259138.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            35318..36493
                     /locus_tag="IXR05_000594"
     CDS             35318..36493
                     /locus_tag="IXR05_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4259139.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            36497..37138
                     /locus_tag="IXR05_000595"
     CDS             36497..37138
                     /locus_tag="IXR05_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259140.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            37135..38052
                     /locus_tag="IXR05_000596"
     CDS             37135..38052
                     /locus_tag="IXR05_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4259141.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            38049..38720
                     /locus_tag="IXR05_000597"
     CDS             38049..38720
                     /locus_tag="IXR05_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259142.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(39261..39749)
                     /locus_tag="IXR05_000598"
     CDS             complement(39261..39749)
                     /locus_tag="IXR05_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAQ4259143.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(39950..40216)
                     /locus_tag="IXR05_000599"
     CDS             complement(39950..40216)
                     /locus_tag="IXR05_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4259144.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(40216..40479)
                     /locus_tag="IXR05_000600"
     CDS             complement(40216..40479)
                     /locus_tag="IXR05_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4259145.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(40472..40744)
                     /locus_tag="IXR05_000601"
     CDS             complement(40472..40744)
                     /locus_tag="IXR05_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259146.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            40955..41140
                     /locus_tag="IXR05_000602"
     CDS             40955..41140
                     /locus_tag="IXR05_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4259147.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(41282..43105)
                     /locus_tag="IXR05_000603"
     CDS             complement(41282..43105)
                     /locus_tag="IXR05_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAQ4259148.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(43703..46408)
                     /locus_tag="IXR05_000604"
     CDS             complement(43703..46408)
                     /locus_tag="IXR05_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAQ4259149.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(46714..47661)
                     /locus_tag="IXR05_000605"
     CDS             complement(46714..47661)
                     /locus_tag="IXR05_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAQ4259150.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            47851..48120
                     /gene="rpsN"
                     /locus_tag="IXR05_000606"
     CDS             47851..48120
                     /gene="rpsN"
                     /locus_tag="IXR05_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAQ4259151.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(48296..48658)
                     /locus_tag="IXR05_000607"
     CDS             complement(48296..48658)
                     /locus_tag="IXR05_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4259152.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(48669..49790)
                     /locus_tag="IXR05_000608"
     CDS             complement(48669..49790)
                     /locus_tag="IXR05_000608"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAQ4259153.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(49806..50156)
                     /locus_tag="IXR05_000609"
     CDS             complement(49806..50156)
                     /locus_tag="IXR05_000609"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAQ4259154.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(50286..51797)
                     /locus_tag="IXR05_000610"
     CDS             complement(50286..51797)
                     /locus_tag="IXR05_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4259155.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(52119..53471)
                     /locus_tag="IXR05_000611"
     CDS             complement(52119..53471)
                     /locus_tag="IXR05_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAQ4259156.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(53624..54700)
                     /locus_tag="IXR05_000612"
     CDS             complement(53624..54700)
                     /locus_tag="IXR05_000612"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAQ4259157.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            54896..56641
                     /locus_tag="IXR05_000613"
     CDS             54896..56641
                     /locus_tag="IXR05_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAQ4259158.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(56921..57358)
                     /locus_tag="IXR05_000614"
     CDS             complement(56921..57358)
                     /locus_tag="IXR05_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAQ4259159.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(57342..58715)
                     /locus_tag="IXR05_000615"
     CDS             complement(57342..58715)
                     /locus_tag="IXR05_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259160.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(59037..59525)
                     /locus_tag="IXR05_000616"
     CDS             complement(59037..59525)
                     /locus_tag="IXR05_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4259161.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(59547..60149)
                     /locus_tag="IXR05_000617"
     CDS             complement(59547..60149)
                     /locus_tag="IXR05_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4259162.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        17104 a        13016 c        10989 g        19083 t
ORIGIN      
        1 tattttagac ttatacgtta ttgtcctgtt tcatttgatg gaggattgta aataaaaaaa
       61 gaggaaagaa cataactttt cgttatcttc tttcctcttt ataattgttt agcttattta
      121 gccaaagctt cttttgcttg gtcagccaat gcagtaaatg ctgctgcatc gttaacagcc
      181 aagtcagcta acattttacg gttgatgtcg atttcagcaa ctttcaaacc gtgcattaat
      241 tttgagtagc tcaagccatt catacgagct gctgcgttga tacgagcaat ccacaattta
      301 cggaagtcgc gtttcttttg acgacgatcg cgatatgcgt agttgtatga attcattact
      361 tgttcttttg ctgttttaaa taaagtgtgt tttgaaccgt agtaaccttt tgctaatttt
      421 agcactcttt tacgacgttt acgagttact gttccacctt taacacgtgc catgtataat
      481 tcctcctaat aaaaataaat cttcagattc tgttatttgt acttcttatt tcatttttgc
      541 tagttgttgg cgaatacgtt tgaagtcgcc actagaaacc atgcttgctt tacgcaattg
      601 acggcgttgt ttttttgttt tgccgtggaa acggtgactt gtaaacgcgc ggaagcgttt
      661 caatccgcct ttaccagtac gtttgaaacg ttttgctgat ccgcggtgtg ttttttgttt
      721 tggcatgact atatttcctc ctcaaaatct ttcgttatcc gactatcggc tgtccaacag
      781 ccagttagtc attcaaatta cttactgtcg tttttcggtg ccagcgtcaa gaacatgctg
      841 cgtccgtcca ttttcgcttt ttgttccact gttgcaatat ccgcagtttc ttcagctaag
      901 cgattcaaga ctttttgacc aatttcttta tgggtaatgg cacggccttt gaaacggata
      961 gaagctttca ctttatcgcc cttttccaag aacttacgtg cattacgaag ttttgtattg
     1021 aagtcattca agtcgatcgt aggacttaag cgaacttctt ttacattgat cactttttgt
     1081 tttttacgcg cttcgcggtc tttcttttgt tgttcgaaac ggtatttacc gtagtccatg
     1141 attcgcgcaa ctggtggttt cgcaccaggg gcaactaaca caagatccaa gtttgcttgt
     1201 tctgcaatat tcaatgcttc tgcttttgtc ttaactccta attgctcacc atctgaaccg
     1261 atcaatcgta actctcgtgc acgaatgccg tcgttaacca tcatatcctt tgctatggtc
     1321 attcacctcc aaatattatg agagaaagaa aagcttaccg aataaacggc aataaaaaaa
     1381 cgagttctct tacagaaccc gcgcgtactt cacctaatag aaccagtgaa aactatctag
     1441 cccagtgaca ttatcaacta aggcgagaag cgggtgcttc tgcttttatt tctcaaccat
     1501 catagtatag caaaaactaa tctttttgtc aatgtttttc atacagtttg tcttcctttt
     1561 ctgaaaatga ttagattagc agactttcta gcagtgattc ccgcttcttt gctatactaa
     1621 agaaaaacga ggtgaaccca catgaaaaaa atcgaaccta ttccaccttc tcttcctctt
     1681 cttacaaagg gagagtttta tttagaagat gaggagatct tctctggtct tctgatcaac
     1741 gggggtgacc aaagctatct cgatgccaaa aatatggtat taagagagag tcatatccaa
     1801 aaacttacga tgcaaaaaac agttttacgt cattttgaat gcagtaatgt catttttgaa
     1861 aaatgtgatt tttccaatct ggagtggatt ggtggcagtt tccaccaagt cgtgtttcat
     1921 caatgtaaat taacaggtac gaattttgcc gaaagttatc ttcgagactg tactttcact
     1981 gattgtattg cttcgatggc ttcctttagt agtacaaact tgaaagctgt ctccttcgat
     2041 cattgtcaat tagaagacag cgaattttat gaggtcactt ggaaaaacct ttttttgtct
     2101 gacaatcagt tgaccggttc gaactggttt cgaacttctc tgaagggatt agactttacg
     2161 actaatttct tcacagcaat cgctttatct caagattctt tggcgggact aatcgtcaac
     2221 caagagcaag cacttgtgat cgcccaagcc cttggtttgc agatcaaaga ctagatcaac
     2281 gaatccgccg ccacagtgca ataagcatcc aaatagataa gaccaaactg atgatcaagg
     2341 cgattcccca tccgaaaacg gaatgggtaa agggtaactg gagattcatt ccgaagaatc
     2401 ctgtcacaat agttggaacg gtcaagatca gcgaccagac cgtcaaaaat ttcatcgtgt
     2461 cattcaagtt gttattcagc aaattattat aagtgccaga gagctggtct aaaatctgcg
     2521 aagctaagtt cgtcatttca actgcttgtc gtgcttcgat cagcgcatcg tccaactctt
     2581 ctttttcctt ttctgacaac ttgcgataaa tagccaatgc cttgatttgt tctaaaagta
     2641 ctacattttg ttttgttcct gtaactaagt aaaccaaacc gatctctaaa tctgaaagtt
     2701 gcagcagatt cttgttcgtt gttttttctc ttaatttcag attaagccgc tgacgttcac
     2761 tattcacttc ctcgattaaa ggaaaaaagg aatcagaaat caaaaacaat gtacgaaaca
     2821 ataaactgta tacactcatg tctggcattc gttccaaaag cgatcgaatt agtcgaatca
     2881 cgtactcggt attcggcgtg gtaaatgtaa acaaaccgtc ttcttttaaa ataaaagcga
     2941 taggactagt ttcataatga ttatcgactt tttgctggtg cggaacattt gatacaagca
     3001 gtaacgcttc atcaaaagaa tcgtactcta cgcgcgcccg ttcattttta tctagagaat
     3061 aagtcagcat ctcgtcacta atgccatatt cttcttttaa gtttttaaca gctagcacat
     3121 cgttttgctg tacattgatc caaaaattac ggtcttgatt aaaatagtgt ttttcccgca
     3181 tactctatcc tcctgacatt tgtttccagt ataaagaaaa aagtcgctca aataaaggtt
     3241 taccctttat ttgagcaact gtaaatcaaa tggctacttt ggtttggcga atctctgcta
     3301 atttttcttc gatcattttc aagacttctt cttttgcttg aggatcttcc acaaaattat
     3361 agcggtctcc atcgatttgg atttttggac tttctttgta ttcttcatac cattgatcgt
     3421 aacgtctgtt caattctttg taataatcgt atagacttgg atcaaaggac aattgttcat
     3481 acgaacgacc acgtttttcg atacgctcca acatcgtatc aaaagataca cgaatatgaa
     3541 ctaataaatc cggatgtttt ttatgggcag catagggaag ttcttccatc atgttttcca
     3601 gcagttcatc atacacacga acttctgttt ctgttgctct tcctagatct gcatttagat
     3661 ggaaaagcag tgaatcttca taaatcgaac ggtccaatac attattgtca tctttcattg
     3721 cttgtttgat gcttgcaaaa cgtttattca aaaaataaat ttgcagcaaa aaagcatact
     3781 gttcagggtt tgcataaaat aagggcaaga cttcattatc atcaatcgat tcataaaatg
     3841 cctgactatc aaagtgttca gccatcattt ctgttaaact tgattttccg gcaccaattg
     3901 tacctgctaa aacgatcacg ctcatttacc tccagctcac ttcatcacta aatattgtgt
     3961 ttaactccaa cctttttaaa tataccccca atatctagta gtgtcaattg tatttttttc
     4021 tagtcaaaga agaaaaaaag tcaaaaaatt cttaagaaaa aagtgttttt tctttagaaa
     4081 acgtattctt agttttactt ctgagatggt tttagtaaaa taaaggagga atgttttttg
     4141 agacccttag tggacaaaaa aattcgtgaa gcagcgcaac tcgttttggg cgctttattt
     4201 tttgcttaaa aatcactttt acgtgagaag gagttagatt atggcaaact atggccaagg
     4261 agaatcaagc ggaaagatca tattgatggg cgagcacgcg gttgtttatg gagaaccagc
     4321 gattgccttt cctttctatg caacaaaagt caccgcattc cttgaagagc tggatgcaat
     4381 ggacgatcaa ctggtttctt cctactattc aggaaattta gccgaagctc ctcatgcatt
     4441 aaaaaatatc aaaaaattat tcattcactt aaaaaaacag catgacatcc aaaaaaactt
     4501 gcaactgacc attgaaagca cgattcctgc tgaacgtgga atgggatcaa gcgctgcagt
     4561 cgccacagca gtcactcgtg ctttttatga ttacttagca tttcctttgt ctcgtgaaat
     4621 actattagaa aatgtccagc tttcggaaaa aatcgcccac ggtaatccta gtggaatcga
     4681 tgcagccgct actagcagct tgcagccgat ttattttaca aaagggcatc ctttcgacta
     4741 cttttctttg aacatcgatg cttttttgat tgtcgctgat acaggaatca aaggacaaac
     4801 aagagaagcc gtcaaagatg tcgctcacct ctttgaaacc cagcctcatg aaactggaca
     4861 aatgatccaa aaattaggat acttgacgaa gcaagcaaaa caagcaatca ttgaaaattc
     4921 accagaaacg ttggcacaga caatggatga atcacaatca cttctggaaa agctgacaat
     4981 cagcaatgat tttcttaatc tattgatcca aacagcaaaa gataccgggg cattgggtgc
     5041 caaattaact ggcggtggac gcggtggctg tatgattgca ttagcacaaa caaaaacaaa
     5101 agcccaagaa atcagtcaag cacttgaaga tgcgggtgct gctgaaactt ggatacaagg
     5161 attaggagta catacctatg tttaaaggca aagcacgcgc atataccaac attgctctaa
     5221 tcaaatattg gggtaagaaa aatgaagaac tcatccttcc aatgaacaac agcctttcgt
     5281 taacattgga tgcattttat acagagacag aagtcatctt ttctgatagc tatatggtag
     5341 atgaatttta tctagatggc accttgcaag acgaaaaagc aacaaaaaaa gtcagtcagt
     5401 ttcttgacct ttttcgtaaa gaagccggcc tctcactaaa agcttcagta atcagtcaga
     5461 atttcgttcc taccgcagct ggattagcct cctctgccag cgggctagct gctttagcag
     5521 gcgcttgcaa tactgctctt aagcttggat tagatgatct ctctctttca agatttgctc
     5581 gacgcgggtc tggttcagct tgccgaagta ttttcggtgg tttcgtcgaa tgggaaaaag
     5641 gccatgacga cttaagttct tacgctaagc cagtcccttc cgattctttc gaagacgatt
     5701 tagcaatggt tttcgttttg atcaacgacc agaaaaaaga agtgtccagc agaaatggga
     5761 tgcgtcggac agtcgaaaca tccagttttt atcaaggctg gttagattcc gttgaagggg
     5821 atctatatca attgaaacaa gcaatcaaaa caaaagattt ccaacttctc ggagaaacga
     5881 tggaaagaaa cggactaaaa atgcatggaa cgactttagc tgcccagcct ccattcactt
     5941 actggtctcc tgacagctta aaagcgatgg atgcggtgcg acaattgaga aagcaaggca
     6001 ttccatgcta ctttacgatg gatgctggcc ctaatgtcaa agttttagtg gaaaacagcc
     6061 atttatctga ggtacaagaa acatttacca aattatttag caaagaacaa gtaattactg
     6121 cacatgctgg tccaggaatt gcgattattg aataaaggga gatttttatg attgaagtat
     6181 ctgcaccagg caaactctat attgccggag aatatgcagt tgttgaaaca ggccatccag
     6241 cagttatcgc tgcagtcgat caattcgtga cagtcactgt agaatctgca cgaaaagtcg
     6301 gaagtatcca atctgcacaa tatagtggga tgcctgtacg ttggacaaga cgcaacggag
     6361 aattagtttt agatattcgg gaaaatcctt ttcattatat ccttgctgct attcgcttga
     6421 ctgaaaagta tgcacaagaa aaaaacattc ttttatcctt ttatgatctg aaagtaacaa
     6481 gtgagttaga cagttcaaat ggccggaaat atggattggg ttctagcggt gccgtgaccg
     6541 ttgcaacggt caaagccttg aatgtttttt acgcgttgaa tttatctcag ttggagattt
     6601 tcaagattgc agcactagcc aatttagcag ttcaagataa tggttcctgc ggcgacatcg
     6661 ctgctagctg ttatggtggc tggatcgctt tctcaacctt cgaccatcct tggctccaag
     6721 aacaagaaac tcagcattct atcagtgagt tacttgccct ggattggcca ggtctatcca
     6781 ttgagccatt gattgctcct gaagatttac gtttattgat tggttggacg ggtagccctg
     6841 cctctacttc tgatttggtc gatcaagttc accgttcgag agaagataaa atggtggctt
     6901 atcagctttt cttaaaaaat agtacagaat gtgtcaacga aatgatcaaa gggtttaaag
     6961 aaaataatgt aacgttgatc caacagatga ttcgaaaaaa ccgacaatta ctgcatgatt
     7021 tatctgcaat cactggggtc gtcatcgaaa cgcctgcttt gaacaaattg tgtaatttag
     7081 ctgaacagta tgaaggagcc gcaaaatctt ctggtgcagg tgggggcgat tgcggaatcg
     7141 taattgttga ccagaaatct ggcattcttc ctttaatgag tgcatgggaa aaagcagaaa
     7201 tcactccact gccgttacat gtctatagcg atcaaagaaa ggaaaaccga tgaatcgaaa
     7261 agacgaacat gtttcactag ctaaagcctt tcatgataaa caaaaaaacg aatttgactt
     7321 cgtacggatc atccataacc ctttgccgca aatagcagtt tctgatgtcg atctaagtac
     7381 acaggcagtt gggtttacac taagcagccc attttatatc aatgcgatga ctggcggaag
     7441 cgaaaaaaca aaaaaaatca accaagatct tgcaatcgtc gcaagagaag cagatttgat
     7501 gattgccact ggttcagtca gcgctgcctt gaaagtccct tctttagccg atacttatac
     7561 gattatgcga caagaatatc ctcacgggaa aatcattgcc aacatcggtg cagggacttc
     7621 tgtcgaaaga gccaaagaag ctatccgatt gtttcacgca gatgccttac agattcattt
     7681 gaatgcacct caagagttgg ttatgcctga gggagaccgt gattttacca attggaaagt
     7741 acttattcaa gaaactcaaa cagccattga cgtccccctc atcgtaaaag aagtcggttt
     7801 tggcatgaca agagaaacgc tcaatgatct agctgcttta ggagttcata cagttgatat
     7861 cagcggtcga agcggaacaa gcttcaccca gatcgaaaac gcccgtcgct ccaagcggga
     7921 actgagttat ttagctgact gggggcaatc gacagtctct tcattgcttg aagcaaatga
     7981 agcagacact tctatggaaa tcctagcctc cggaggtatc cgcaatgcct atgacatatt
     8041 taaagccctt tgtctcggcg caaatgccgt gggtacttca ggaaccgtac tgacgcatct
     8101 gatgaatcac ggcgtagaag aaactattat actgatgaag caatggcaag aagagcttcg
     8161 tctgctttat actatggtcg gcgcaacgaa taccgcggcc ctacaccaac aatctctgat
     8221 cttttccgga ccagtgaagg attggtgcga agcaagaggg atcgacttag tgaagtatgg
     8281 aagacgcaca gaaaagagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa
     8341 cacgtacaaa cggcggaagt aaaagcaact ccttcggaaa taagctgaaa ttcacaaaaa
     8401 tttgaaaagc aattttcgtg aattccttct tatttcttgg agttaaatgc ttctgtccca
     8461 gcctcttttt tcgaataaat gatgtttaat cagctgtcct tcggtattcg ttcaatccgc
     8521 tgatttcaca acctctccac taaacagtgt actaaagctc ttttaaggtt gttttccgat
     8581 ataggcaagt atgcctccgt ccacatacaa gacatggccg ttaacgaaat cagatgcgct
     8641 agaagccaag aagacagatg gtccagccaa atcgattggc tcgccccagc gtgctgctgg
     8701 cgtacgtcca acgataaatt gatcgaatgg atgacgttca ccgttttctt gtgtttcgcg
     8761 taatggagca gtttgcggtg tagcaatata acctggtcca attccattac attggatatt
     8821 gtattgaccg tattcagaag cgatgttttt cgtcagcatt tttaatccgc cttttgccgc
     8881 agcataagca ctgaccgttt cgcgtcctaa ttcactcatc atggagcaga tattgatgat
     8941 tttaccgccg cctttttcga tcatatccgg aataactgct tttgaaacga tgaatggggc
     9001 atttaaatcc acgtcgatta cttggcggaa gtctgccgca tccatttcga tcatcggtgt
     9061 ccgtttgatg atccctgcat tgttgactag aatatcaact gaacctacat cttctttgat
     9121 ctgttgaacc atcgcttgaa ccgcttcttc atcggtcaca tcgcagacat aaccttttgc
     9181 atcgatgcct gcttctttat aatgcgctat accttcatca actgattctt gattcaagtt
     9241 attaaatacg atttttgctc ctgctgtagc taaagagcgt gcaatctcaa atccaatacc
     9301 atagacagca ccggtgacta atgctacttt tccatctaaa cgaaacatat ccatactaaa
     9361 ttccatcatt ttctctccct tatgcttatt ttaattgatc catttgcacc atatccatgt
     9421 ctgtataggt gatattttct ccgcacattg cccagatgaa tgagtaattg cttgtaccta
     9481 cacctgaatg gatcgaccag cttggcgaaa taatggcttg ttcattgtct acaactaaat
     9541 gttttgtttc atctggtttg cccatcatgt ggaacacacg tgtatcttca ttggcataat
     9601 caaagtagac ataagcttcc atacgacgtt catgtgtatg acaaggcatc gtattccaag
     9661 cgcttcctgg ttctaaaatc gtataaccca tttgtaattg acagctttcg catacatttg
     9721 gatggatgta ttggtagatt ttacgttcat tcagtgtcag gccttcacca gtctccattg
     9781 gttttacttg gtcgatactg atttttacat ttggatattt atgatgagct ggaacagaac
     9841 taatatagaa tttagctggg ttttcagcat cttgagaaga aaatacaaca tgtcgtgttt
     9901 cttttccgat atagtatccg tcttgttttt tcatttcttc tttttgccca tcgatctcga
     9961 tgaatcctgg tccaccgata ttgatcacac ctagttcacg acgctctaag aagtaatcaa
    10021 cacctagttc tttgtctaat gtgatttcta attctttttc agtaggtgtc actccaccaa
    10081 agatcattcg atcgttgtgc gtataagtca aactgatttt ccctggttca aatacctttt
    10141 ctactaaaaa ttcttttctc aattgttccg ttgaataatg acggatatct tctggactgt
    10201 gtgtataacg tgtttccatt tcttgcattt tcttctactc cttctatcga atgatttttc
    10261 cagagccgca tgctaaaaat tgtgcgactt cttcttgact aaattggttg cagtccccat
    10321 ggatcgtatg cttcaaggca gaagctgccg tagcaaaatc aatgatttct tgcggagaca
    10381 tattggataa aatcccatgg agcacgccac ctgcaaaagc atctccgcca cctactcgat
    10441 ccacgattgg ggtgattcta tggacttggg attccacata ttcatggttc atccacaatg
    10501 tccccttcaa ttcattttca cttgctgaat gaacggtacg cttggtcgaa taaaacacct
    10561 gaatattcgg gaacttttcc tgcatttttt gataataata aattagaggt tgttcttctg
    10621 cttctggcgc tttctcgata cctaacaaat aaagagcatc catttttcca gctgagcaga
    10681 tatctactaa aggtaaaagc tgatggatta cttcgctggc ttcttgctgt gtccataatt
    10741 ttccacgata gttgatatcg aagctgatca ggcagccagc tttttttgca gcttctatca
    10801 cctgtttcgt cattttttgc cattttttag acaaagctgg ggtgattcct gaaacatgaa
    10861 atatatctat tccttggaat aactcctcta gcgaccattc caaatgatcc atttcagcaa
    10921 aacttgatcc ggcacgatca tagatcactg aggcggcgcg ttcgccacta ccagtttcca
    10981 tataataagt acctagtctt gatccaccag ataatacctg tttcgtatct actccataac
    11041 attgcaagtg ctttttgact gcttttccca atgcgttatc aggtactttt gtagcaaaaa
    11101 tcgcttcatg tccgtaatta gctaaagaaa ttgctacgtt tgcttcccct ccgccataat
    11161 gggcagcgaa tcgttcactt gaatcgatac gggttccctg ctctgtggac aatcgcaaca
    11221 tgatttctcc gagtgtcact acttttccca taagcagcta cctcttgatt tctttcattt
    11281 ttgctgcata ctgttgcgcg acttccgtta ctttgtcaaa atctcctgta gctgcgggtg
    11341 ctaaaaggtt cccacctact ccgactgtta cgacaccagc atcgaaccac tctttcatat
    11401 tgtccagact cacaccgcca gttggcatga tattgacttg aggcatcggc gccttgaagg
    11461 cagaaatgat acttggtcca taagcgcttc caggaaatag tttgacgata tctaccccgc
    11521 ttttcagcgc tgttttgatc tcggtaatag tcatacatcc tggtaagtaa ggaatttgat
    11581 acagattgca catctctgcc gtttcttgat caaaggaagg gctaacaata tactctgcgc
    11641 cagctaagat agccaagcga gctgtgacag cgtctaatac tgtgcctgcg ccaatcacta
    11701 tttctggttg gtctttgtag aatgacaaaa gttctttgat tacttgatct gcttgaggga
    11761 ctgtaaaagt caactcaata ccagttagac cacctttgat gattgcgtgg caagcattca
    11821 aagcttcttc tttgcttttt ccgcgtacca ccgcaatcac tccggcgttt ttcaatcgag
    11881 ataaaatatc aatttttttc atcttctcca cctatttcct atttagaaat tttattttat
    11941 aacttggaaa tctataccca tattatacgg cagaaaagaa aaattgcaaa cgcttttttc
    12001 attatttttg aattctttgc tcgatttcgc tttttgtttg cttgagggca ctgattattt
    12061 gttcttttgt ctcatctgtt aaacgatatt tcggcatact tacactaaat gcaccaatga
    12121 tttgttcgtt tttcacgatt gaggctccta tacaaaaaat atcacgttcg atttcttcat
    12181 cgtcaaatgc gatgtgggtt tcttttaccg ttttgatttc ctttttcaac cgtaatgcat
    12241 tggtgatcgt atattctgtg taagggatca acggatgctt ttcaagataa tcagtgtact
    12301 gctcttcact gaattctgct aatacggctt tgcccatcgc agaattgtat aatggtcggg
    12361 tgattccgat ttttgaagac atgcggatcg tttgatgttt tggatctagt ttgttcacgt
    12421 acaagatctc attgttgtcc aataccccta agtggatagt ctcatcgatc ttttgctgca
    12481 gctgttctaa aaacggtaaa gtcaactcta ccaaatcgat ttgttcaatg tttttattcg
    12541 cgtagcgaat aagctttgca cctaaacgat agtttttctc tgaattttta tttacgtagc
    12601 cgatcatcaa caaagtatct agtattttca agactgtaga agaggtcatt cccacaccct
    12661 ttgcgatcgt ctgcaaagag acatcttggt tttccgctaa atagtctagt attttagagg
    12721 ctttgatcaa tacagttcca taaggctttt tattttccat ataatattct cctatttctt
    12781 tataagaaaa attatagcgg aaataccatc aatttaaaag agatatccag atataaacta
    12841 ccatttctct ttacaggcaa tttaatgttg aagatccgct tcgtttttac atcaaacttt
    12901 gatataaagc aatgatttct tctactgtcg tttctcttgg atttcctggt gtgcatacat
    12961 ctcgcaaagc atcttctgca attgctggaa tatctgcttc ttttacacct aattcagaaa
    13021 tggtttctgg gattccaacc gctttgctca accgatcgat ctcaccacaa gccgcttctc
    13081 ttacatcttc taaagacatt tcagctgctc ctttaatccc tagaacaaga gcgatctcac
    13141 ggtacttttc tccagtatat tctttgttat atttcatgac agttggcaaa agtgctgcac
    13201 acgctacgcc atgaggaatg ttgtaccatg cacttaacgg gtgagccatc ccgtgtacca
    13261 gtcctaaacc gacatttgag aagcccattc ccgcaatata ctgtcctaat gccatttttt
    13321 ctcgcccatt ttgatcgcca tctacagaag cttccaaaga atggccgatg atttcgattg
    13381 cttttaaatg cagcatatca gtcatttccc aagcgccttt tgtgataaac ccttcaatag
    13441 catgcgtcat agcatccata cctgttgatg cagccaattt tttcggcatt cccatcatca
    13501 tatcgctgtc gatgaacgcg acgattggga tatcatgagg atcaacacaa acaaattttc
    13561 ggtgatttac ttcatctgtg atgacgtagt tgatcgttac ttctgctgct gttccagaag
    13621 tcgttggtat agctaatata ggtaaacatg gatttttcgt atcagcaaca ccttctaaac
    13681 taatgacgtc tgaaaactct ggattcgtca aaataatccc aatggctttt gccgtatcga
    13741 ttggcgaacc tccaccgatt gcgatcaaac agtctgcctc tgcctcttta acaaaagcca
    13801 ctccatcttt tacattttgg atcgttggat taggtacgat cccgtcgtat aaagcataag
    13861 cgattgctgc tttatctaga agttctgtta cttttgttgc tataccgtgc tcgatcaatc
    13921 ctttgtcagt aatgacagct gctttgccga atcctcgctg ctgaaattca gggacgatcg
    13981 actcaatcgc tccttttcca aaatacgatg tttcatttaa aatcattcga ttactcattt
    14041 tctattcctc ctaatttgta ttatttttca caataaaaac gaaagaaccc caagcaaccg
    14101 gttgcccagt tgcttgttgc tacagttcaa agactggcat caattcccaa ctgactggag
    14161 aggcatctgg atttgtctcc atgatatctt ccatgtactt ccaccatttt tgattgatag
    14221 atgtatttgc cattttttcc cataactttt catcttcgat cactaagtaa ccaaataaca
    14281 aacttgtact cggatcaaga tagatcgaat agtcgatgac cccgtgttca cgaagtgctg
    14341 tacgcatttc tggccaaagt tcatcatgtc tttttttgta ttcttcttgt ttttctgggt
    14401 aaactttcat gcaaaaagct tttttcacca tgtcagacac ctgctttcgt atgaacttcc
    14461 tccaaataac ctgcttttgg agtgacacca aacgcatctg ctaaatgcca caggttttcg
    14521 tccgtgattg tttgcaagat tggtccttgc gctttgacgt acgtatagac ttctgctgcc
    14581 ttttctgctg tctcgatcaa accaaagact tcatccatgt cttttcctga cccgtagatt
    14641 ccatgttgtg gccataaaac caatcgagtt tctttcattt tttcagctgt tgcttcccca
    14701 atctcatttg ttcccggaac catccacgga atgatggaaa ttccttctgg aaaaacaact
    14761 aagcattccg tacacatttg ccatagcgta cgactaaagg aacgttcgtc taattcatgc
    14821 gtaaaactca tcgctaatag atgactagca tggcaatgca taacgatccg attatctggg
    14881 tctacttcta aacgggcgat atgactcatg aaatgacttg gcaactcgct tgtaggaagg
    14941 cattcgtttt ccagccccca caaaagttcc agtgttttgc catcttcagc aactcgaacg
    15001 attccaagat tctcggcagg ttcgctcgct acatttttaa aatatcttcc tgaaccagtt
    15061 acaataaaat agcatcctgc taaacggctg gcatcaaaaa tcatcgagat gcggcggatc
    15121 actttttcag gatccaagaa cggtgtgatc tcttcttctt ttagtaaata agaaatattc
    15181 ccgccatttc tttcatccca tcccaagcga taaagattcg acgtcgtttc gatcatttct
    15241 ttcacataag gcgcttgtaa aatatctatt tttttcaata tagccacact cctattttct
    15301 taattccaac acgtcttttt gatattcctg gacttcttcc agccaatcca aaccaactgg
    15361 aacttgattt ttgtaacaga aataattcca tacatcggca tacgggaaat ctttcaattc
    15421 ttccgtataa gccattcttg aagtaaagtc aaaagccagc tccatttctt tcaatcgctc
    15481 aactggttcc agcatagctt tcagcagtgc tttttgtgta tttctcgtac cgatgaccca
    15541 agcagcgata cggttgatcg ttgcatcaaa gaaatccaga ccgatatttg ttttttccaa
    15601 caattcgtta cggactaatt ctttagcgat ttcctgcaat tcatcatcca tcaaaaccac
    15661 atggtctgaa tcccaacgca ctggacggga aacatgcaac atgattcctt tgctgaataa
    15721 agctaatgaa gataatttat tggaaatcac ttctgttgga tgaaaatgtc cagcatctag
    15781 acaaacaagt ttgtcacgag tcaacccgta acccatataa aattcatggg aaccgactgt
    15841 ataagcttca gcgcctaaac caaatagttt gctttctact gcatcttgta cataccgttc
    15901 atctaactct tctgtaaaaa tttcatcgag tgattccatt aaacgttccc gtggggtaaa
    15961 acgatcaatc ggattatctt tcatcccatc aggtacccaa aagttattga tacttgtttg
    16021 cccagtttct ttcccaaagt actccgcgat tttgcggctt cttttcccgt gttcgatcca
    16081 gtattcacga acttctttat ctggatgagc caatgtaaag ccgtctttca tcattggatg
    16141 cgaaaagaaa gtcggattga agtcaagacc gatttcttct ttttttgccc actctaccca
    16201 tttttcaaaa tgtttcggct caatttcatt tagatcgaca gattcttctg tatccaaata
    16261 gatagcatga aggttcaatt tgtgtttgcc cggtatcaac gaataagcct tctccagatc
    16321 ttgtctaagc tcttcaggtg ttcgtgcggc tcctggaaaa ttccctgtcg ccatgattcc
    16381 accggtcaat tcgccatccg gtgtcaagaa acctttgaca tcatctcctt gccagcaatg
    16441 catagaaatt ttgatgtcct gtatcttttc tagtacagca tctgtatcta caccgatagt
    16501 tgcatatttt tcttttgctt gttcgtaatt tctttcaatc gtgttcatac gattactcct
    16561 ttgattttat tcacgtacca ttccatcgtg ttttgcttat tttcatctgg gtaaaaagtt
    16621 tcacatggaa acgactgttt gattacattt cttgcttgtt ctatattcga aaactgacct
    16681 gtactgagca tttgcatggc aacattcccg attgctgtgg cttcactagg tcctgcttct
    16741 acaatgattc cggcataatc tgctgtcaat tgattcagta gacgattatt cgatccgccc
    16801 cctacgatgt gcagcttttc caatttcgtt ccagttaagt gttctacttt gatcagctct
    16861 tgtgcgtaac aaagagcaag attatcatac acacaacgag cgatagctcc cgatgagaca
    16921 gggactggct gctctgtttc aaaacagtat tgctgaatct cttctatcat atttggggga
    16981 ttcaaaaatc gagggtcatt gatttccatc acttgctgca gcggtttttc ttttgcagca
    17041 agctctgcca attccgcata actgtactcg tactcttgca ttcgggcaac ttcctggatc
    17101 aaccacatcc ccatgatgtt tttcaaaaaa cgcaccgtgt tatgggcacc ccattcattc
    17161 gtataatttt cagaaaaagc attgcgagaa acattggcga tctttgtttc aatccctaaa
    17221 agcgaccatg tcccactgct gatataaccc caacgttctc cttgacctgg cgttcctaat
    17281 acagctgacg ccgtatcatg acttgctact gtgataaagg tcacatctgg caaatcatat
    17341 tttgaaaatt gttctttttg cagatctcct agtatcgttc ccggctctgt caatggtgga
    17401 aataattcct tcgagacacc gattttttca agaagttcta tttcccattc ttttgtccct
    17461 gcattcagca gctgcatagt agatgcatta gttttctccg tcaccatgtt accagtaaag
    17521 acatacccta aataatcagg tatcagtaac aatttatgtg cttttgccaa attttctttt
    17581 tcttcagcaa acaattggaa caaggtattg aaaggctgga tctgaatccc tgtctgctca
    17641 tacaacttat ctagagaata gatttcagaa aactgttcta ctgctccatt ggtacgcttg
    17701 tcccgataag caatcggatc atttatccga tccccttgtt catcaatcag acagtaatcg
    17761 actgcccatg tatcgatccc cgcaaaaagg cgatcaatcc ctgtctgctt taatttttca
    17821 aatccaatca aaatctcttt gataagataa tcgatcttcc agcgatcgtg accgtctttg
    17881 ttccgaaagc cgtttttgaa ccggtgtact tcttccaaga tcaaagaacc ttttgcatcc
    17941 ctcgtacttt tcattagtcg tccgcttgat gcaccgatat cgatggcaac aaatgttgga
    18001 ttcatttctc cacctctttt actttattgt tgattagcac tttattaata aagcgttatc
    18061 atttattgac aatgctatca taatacagaa tcttatattt tgcttcacac tattttggta
    18121 tataattgca ttatcttgac aagttgggag tgtttacatg gattactggg aaaaagccaa
    18181 ccactcatgg tcggaagact caaaaagagt gatcttgacg cctacacaaa gaagcaggaa
    18241 tttatttttt tatatccaag aaatcggtta cttcaaagca ccaatccctt actatactga
    18301 acgagcacat ttaccttctt acttgataaa gtttactttg tctggcaaag gttcgcttac
    18361 atataatgat aatcagcaac agctaaaagc tggagactta ttttttattg actgccaaga
    18421 atatcagcgt tatcaaacga tcagcgaaga accatgggaa atggattgga tccatttgaa
    18481 tggtcagaac gtccaatcat tttatcagga gttcacaaaa gacggccata acaccttcca
    18541 ttcaacagga gatccatcag aaaacaagat ccaccatttg atcacagaat tgatccacat
    18601 gcaacaaggc acgaatgccc gtaccgattt ccagtcctct gtagctatcc acgagttgct
    18661 gaatgaactg attttgcaaa agtatcagct agatttcgaa gaagaggata ttcccgccta
    18721 cgtttacaaa ctgaagcaat acttagacga acatttcaaa gaaacgatta cacttgatca
    18781 attagaacaa caattcttat tgaataaata tcagctgagc aaagattttt ccaaatttat
    18841 cggttctcca ccaatcgatt atttgatcag caaaaaactt tcttacgcta aagaccttct
    18901 tcggtataca gaatttacgg ttcgaatgat ttccgaagaa atagggattg agaattttgc
    18961 ttactttagc cgcctgttca aagcaaaaac aggactatcg ccgagagact ttcgtaaatt
    19021 cagctgattc atataatatg tacgtcattt tttcaaaata ttttgaaata tatagataaa
    19081 aataaaataa ccgcagtttc tgcttctatg taaacaacag cagctactgc ggttattttt
    19141 tagtgatcat tctcattgtt catcttcaaa atgttcataa tgaaccaact gtttctgtgt
    19201 atcacgtttc aaaaattctt taggcgttat gccgaactct ctcttgaatg ctttcagaaa
    19261 atgcggataa gaagaaaaac cacttttact atatacagca ctagagctgc ggtattctcg
    19321 caacaagtgc ttggcataga tcagcttttt cttcattaca tactgatgaa acgtaaatcc
    19381 agtgtacttt ttaaattctc gtgtgatatg gtatttgctg acaaaaaact gcttttccat
    19441 ttcctctaaa gaaagcggat gagataaatt ttttgagata tattgtaaca tttgttccac
    19501 acgctcatta ggaactacag cattctgttc ttgcgcactc tcttcttttt gtacaacttg
    19561 attgagaaaa atcaagtatt ctaccagagc ttgttcatat tttatgtctt caccgtaaat
    19621 ttttttatca ggaggatggt cgataaatga taatttttgc ttcaatactt cctgttctat
    19681 ttgcaataca cgactcctct tctctcccat tggttgaaaa caagccgata gattagacca
    19741 tggcgtggaa cgactttcta gaaaagaagg ggtgacaaag atatagacac gctcgaatac
    19801 atctgaagat tggcggacga tacgatgcaa atcattggaa tggatgagca gcacacttcc
    19861 tgctttgatc gtaaattgtc gtccgttcaa ataaaaagtc gcttctccct ttaatgtagc
    19921 atggatctca tagaaatcat gatgatgata gatcgtttta ttttggctga cgacatcttt
    19981 gacatgatag atttcatact gatcagaaac catcgtattg acttgttcac cgctgatttt
    20041 cttttggagc atgtgccgca cctccttttg ttcacttatg cacaatttta ttataccacg
    20101 ttttttgtaa tcaaaaagag ctgcttttat atactcttat aaaaaagaag agacgtggca
    20161 tcttctagcc ccgccccctc cattctaaat attagttaac caacgtcttc tttacattat
    20221 tcaagaagac ttcttccata acgaatccca tcatcttttg tttcttcaag aaccacatac
    20281 aggtacggac gattcttcat gatgatttct ttgatttttg tgtactcgat cacaccgtct
    20341 cccaaattta ccggcacgat tttttcctgt tcgacacgaa aatctttcaa atgaaccgca
    20401 catatctttt caccaaaacg ttcaaaagct tcttctacca attggacttg ttcttgataa
    20461 tcactacttg tgatcaaatt ggtcggatct aaaatgattc ctagatagtc cgaatctact
    20521 gcttggatca gctgctctac ccttgctaaa gaatacaccg gatgattcaa acctggttct
    20581 atccccacca tcatttggta tttttctcca gcttttacca agcgacggat aacggacaca
    20641 gcttcagcaa atgcttcatc tgtgaaattt tcttccgtat attggatttc cggcaaaaca
    20701 catccagttt ccgaagcaac catcgacgca ccaaaggaag aagcatagcg aagatactgc
    20761 tcgaactttg tcagcaactc ttgtcgtatc gttaaatctg gatgaatcat attgatatag
    20821 caacttaaaa ttcctacggt cacttcttgc ttttctaaaa ctcgtttgac ataatttccc
    20881 atcccagaat tgatctcatt tgcgccagaa ggtatttcag gaaacgaaag acctaaggcg
    20941 agctgcagtg tatgaatccc ttgttctttt gttttttctg caagatcttc tatcgtttgg
    21001 acttcggaaa gatcatgtcc tctaattgta atgttcaaca taactattct cctaactcag
    21061 catattgggt agccacatga cgatttgcgg gaagtaagta atcaaaaaca agacgactaa
    21121 gataacccca taaaaaggaa gaagcggttt cagcattgcc tctgctttta cgcctcctac
    21181 acttgcaccg acatatagtc ctgtacctac tggcggcgtg atggagccta cacacagatt
    21241 catgattgaa aacaacccgt aatgtacagg atcaacccct acacttgtga cgattggtaa
    21301 aaatattggt gtaaaaatca agatagcagg cgccacatcc ataaacatac ccaccagtaa
    21361 taacacaaga ttgactaata acagaataat aaatttatta tccgttacgc ccataatcaa
    21421 cgaactaatt gcctgaggaa taccggtaaa cgccatggcg aaagacatca tggaagaagt
    21481 agccaataag aacatgatcg tccctgacat tgctactgat tgaaacaaca tattaggtat
    21541 atcttttagt tttaccgttt tatagtaaaa catagcaatc aacagggagt aaatgacagc
    21601 tatcgctgaa gcttctactg ctgtaaatat ccccgtcaag ataccaccga taatgatgac
    21661 aatcaataga aggctaggaa tcgcctcttt tattattttt ccagcatgag ccatctgtcc
    21721 tttttcgaca acagggtatt tattcttttt agcaacgatg aatgctacta gcatgattcc
    21781 tagcgcccac aaagcgccta cgagataacc tcccataaac aaagcagaga tcgaagcacc
    21841 accagcaaca agtgaataca tgataaaagc agtacttgga ggaatgacca tacctgtcgg
    21901 agctgacgcg atattgaccg ctgtcgcaaa cttccggtca tatccttctt ccacttgctg
    21961 agggatcaac actccgccaa tcgcggtaga agcggcaatg gccgagctag agatggaacc
    22021 aaataaagca ttccctaaca cattcgtatg agccaaagcc cccggcacgc gcccgacgaa
    22081 caacatcgca aaatccacta gtttcttagc tatccctcca ttattcatga taatgcccga
    22141 gagaacgaaa aacggaatag cgatcagcga aaaactattg atacttccca ccattttttg
    22201 agctgaacta aaagcagaaa catcaaacgg tataactaac aataaagtca tcatcgatga
    22261 gaatgcaata cttatagcaa tcggcatccc taatacaagc aacacaacaa atacaaaaaa
    22321 taacactaat ccggcttcta ttgccatttt attcctccat ttttatattt tttcttgaat
    22381 tgctggcttg ttgcttaatg tatcgattag attgatcagg ctatagataa tgatgagtac
    22441 ccccgataca ggtactgaca gataaacata tcccatagga atacttaaag aaggcgagat
    22501 ctgccccatt gtcaatgtga cagcattcca tccgccatac accatgatca tcgcagcaaa
    22561 taccagaaat aaactttgaa caacaacttc taaaatttta ctttttttgc cagttaattt
    22621 ttcacttaaa accgttacgg ctaaatgtgc tttttgtccc acaacatacg cggaagacaa
    22681 catggcaaac cagacaagac cgaatcgaac aagctcttcc gtgaccgtat ttggatttcc
    22741 taaaaccgtt ctggaaaata cttgccataa aacaacagcg accatcccaa caagcaaaac
    22801 agctcccagg atctctaata ccttgtttaa aatcattttc atcacagcta cgctccttgc
    22861 tcttggatct tttgataaag gtctttgtag gtaggatcgt ttttgaatat atcatgaagt
    22921 ggggcaactg cctctcgaaa cggtgtatta tctacatcat tgaattggac tccatgttct
    22981 tcttgtgcta aagctttttc ttcttcaatt gcttttgcaa aagcttcaat ttcaaaaacc
    23041 gttgattctt tcgctgcttc ttcaatggct ttttcctgct catcagttag ctgttctttg
    23101 atggcatcat tcatgatgat gatatctggc acacgtgtat gctcatcata ggaatagtat
    23161 ttagccacac caccatgtcc agctgtatac aagacaaatt cattgttttc tgatccgttg
    23221 atcaaattgg attgaagaga cgtgtacact tcatcacttc ccataggtac gggcgaaccg
    23281 cctaaaagct ctaccatttt gatagcggtt tcgctttgca tcacacggat cttctttccc
    23341 ttcaaatctt ccggcgtatg gatcggaccg tctaccatat aaaagctgcg ctgaccagaa
    23401 tcataatagg tcaatccggt aaatcctaaa tttttggtcg attggtagat tggctccatt
    23461 atttcttcat tatccatcac cttaaagaaa tgttcttcat cattgaatag ataaggaact
    23521 gaaaaaatcg aataatcttt agagaaactt tccaacgctg aggcacttac ttttgtgaaa
    23581 tctactgctc ctgactgtgt caattcgatc agttcacgtt ctccacccag ttgtccatct
    23641 gggaaatact ggatctgtac ggaaccatct gttttttctt ttactaaacg cccaaattca
    23701 ttcattgcat caattactgg ctggctgttg cttgcataag caaagcgcaa ggtaactatc
    23761 tcatttacat ctgcatctgc gacagttgcc acactagaat tatttccgca gccgcttaga
    23821 cctagcagac ctaggctaag cgaacttgct gcaaacagca gtgatgtttt tttcatatgg
    23881 gtttcctttc ttttaacaat aagagacgag caattctgtc aaacaaagca ccgttaacga
    23941 ctgtccataa ggcattgctg tgattccgat attccgataa aaatctaaac tgtcccccat
    24001 tcctgtcccg attgaaacgt tttgaacttc tcctttttca tcgatttgtt caagcaatcc
    24061 ttggatagca cgataagcga cttctttata ttcttgtggt aaataacgtt tatggaccgc
    24121 tttcaaaata ccgtaagcaa atcctgcagt tgcagaagat tctacgtaag aagaaggatc
    24181 atccaacaac gtatgccata aaccgctttc agactgataa gtttttaatg cacgcacttg
    24241 tgcttcaagt gtttcgatca ataatttgcg caatgcatct tctttcgata attctaagat
    24301 ttcaatgatc tctggaatag caatcgtcaa ccagcagttt ccacgagccc aaaatgcttc
    24361 ggcatagtta tgatttcctt caaacgtcca gccgtgatac cacaatcctg ttcgtttatc
    24421 catcaagtat ttgatatgga tcataaactg gtaacgagct tcttctaaat attctgggcg
    24481 attcaacagt ttcccgattt ttgccaaagg aagcactgtc atcatcaatg tatcgtccca
    24541 caactgattc ttattttccg gtccatatgt ggcatgctgt aacccgtctt catttgtccg
    24601 aggcatgtca ttcatgaccc attctgccca ttgttctaaa taaggcaaat agcgtgaatc
    24661 tttcgtgtct tcatacaagt aagccatagt caatagcggt gccattgtat tgacgttttt
    24721 gggcggagcg ccttcttcca tacgatcctc aaaccattca ttgaccactt gataagcgcg
    24781 aggatttttt gtcatctggt aatttttata aataccatat agaccgacac cttgtggcca
    24841 attccacact gtccagcttt tgtcatctac tttcagtcca tcaaagtcca acaaaaattc
    24901 accattatcg tctttgatcg ttgtcaggtt ttcaacgagc aggtcaattt tttctttcac
    24961 taattcttta ggtacaaaaa tctcttcttt aataatcatc tttacgccac ctttttaaac
    25021 gctttcattt tatatcctta atatagcagt aataccgtcc actataaata tcgctttttg
    25081 aacaaaaact gtctaaaatt gacctaaatg ttaaataaca aaagtaactt tcagttactt
    25141 ggaaattaaa aaaagaactt ggagaaacaa cgttttccaa gttctttttc atctattttc
    25201 ttatcttttt tctacgcttt cttttgctta tccgttgtaa gcatcaatga tgatctgttt
    25261 caattcagag atcaatggtt ctttcggatt agctgtcgta cattggtctt cgtaagctaa
    25321 ttcagccata cggtctacgg ttgtatctag tgtttcttgt gtgactcctt gagcttttag
    25381 actcatgttg atgccgacag attttcctaa ttcataaaca gccgttgcta aagcttcgac
    25441 taattcctct gttgtttcgc ctttcagacc taagaatttt gcgatatctg cgtaatctgt
    25501 atctgcacgg aaatagtcat atttagggaa catcgcatgt ttttgtggat cttttgcatt
    25561 atagcggata atatgcggta aaagaatcgc atttgtccgt ccatgaggga tcccgtattc
    25621 cccgccgatt ttatgtgcga ctgagtgaca aatacctagg aatgcgttag caaacgccat
    25681 accagccatt gtagaagcgt tgtgcatttt ttcacgtgat tccatatcag gtgtttttac
    25741 tgatttttct aaatagtcaa agactaactt gattgcttgt aggctcaatc cacgtgtata
    25801 atctgaagcc atgactgaaa cataggattc gattgcatgt gttaacacat ccatcccggt
    25861 atctgctgtg acagatgctg gaactgacat gacgaattga ggatcgacga ttgcgacatc
    25921 tggcgtcaat gcataatctg ctaacggata tttcacatgt gtttcactgt cagtgatgac
    25981 cgcaaatggc gttacttcag aaccagtccc tgatgttgtc gggatacata cgaattgtgt
    26041 tttttctggt ttgtcgatct tatatgtccg tttacggata tccaagaatt tttgttttgc
    26101 accaaagaaa gatgtgtctg ggtgttcata gaacatccac attcccttag ctgcgtccat
    26161 tgcagaaccg cctccaagag cgattactgt atctggcttg aagtctgcca tcagtttcgt
    26221 tcctgcgtat acggtatttg tcgatgggtt cggttcaaca tctgagaaga cttcgatctt
    26281 cacatcattt ttacgtcgtg ccaatacttc acgaactgta tcgcagtaac cgaattggac
    26341 cataccaggg tcacaaacga tcatgacacg ttcaacgttt tccattttct ctaagtacaa
    26401 tagagagttc ttttcaaaga agatttttgg cggtaatttg aaccattgca tgttatttct
    26461 ccgtttcgct acagttttga cattgattaa gtttacagca gagacgttac gagaaacaga
    26521 gttcttacca taagaaccgc atcccaaagt caatgacgga atcatttcgt tatagatatc
    26581 accgatgccg ccttctgcag atggtgtatt cactaaaata cgacaagctt tcattcgaag
    26641 accgaatttg acatgcaact cttcgttttc tgaatggata actgctgtat gtcctaatcc
    26701 tccaagattc aacatacctt cacacaaatc aaacgcatgg tccgtgttgt tagctttgat
    26761 catggcaaga actggagaaa gtttttctct tgatagcgga taatctgggc ctacgccttc
    26821 caattcagca atcagcattt tcgttccttt tggtacactg attcctgcca attttgcgat
    26881 ttccatcgca gaatgtccaa cgattgatgg attgaccgca tattttcctt cgttcatcac
    26941 tgcatcttct aatttttgca attcatctgg ttttacgata taaacttggt gtgcttggaa
    27001 ttctgctttt actgctgcat agatttcttt atccacgatc acagcttgtt cagaagcaca
    27061 aatcattcca ttatcaaatg ttttcgaaac gatcaaatcg ttcactgcac gtttaatttt
    27121 tgctgttttt tcaatataag ctggtacgtt acctggacct acacctaaag ctggttttcc
    27181 tgtagagtaa gcagacttga ccattccagc tccacctgtc gctaagacga tcgcgatacc
    27241 tggatggttc attagcatag aagtcgcttc gatcgaagga tgttcgatcc attggataca
    27301 attttcagga gctccggcag cgatagcagc atcacgtacc actcgtgctg cttctgcaga
    27361 agatttttgg gcacttggat ggaaagcaaa aacgattgga tttcttgttt tcaacgcgat
    27421 cattgatttg aaaatcgttg tggaagtcgg attcgttgtt ggagttactc cgcaaaccac
    27481 accgactggt tcagcaattt caatcaaccc tttttggaca tcttcattga tcacaccaac
    27541 tgttttatca tgtttgatat tatgccaaat atattcggac gcatacatat ttttgattgc
    27601 tttatcttcg taaacaccgc ggcctgtttc ctctacagcc atcttcgcta atggcatatg
    27661 ttgatccaaa gctgccattg ccatttcatg cacgatatgg tctacttttt cttgatcaaa
    27721 gctttccatt tctttcaatg ctgcatttgc tttttctgcc aaatcatcaa tcattgcttg
    27781 tacgtcaatt gtcttcgttt tttctttttc tattacttta gccatcatta tcctcctaat
    27841 gggtcatggt tatttgttaa ataattcaca tgtatatcat acaatattta tttttctatg
    27901 taaacacttt tttgtgattt ttttcacagt tatttttaaa tataaaattg ctttatttac
    27961 aggtgtttgt atagaaaaat atataaagtt atttattatt atttatatga cacacccgat
    28021 tattcaatat tgagcaatat atcccatgct cttatctctt tcttttttga ataaaaaatg
    28081 aggtaggaca tctttctgcc ctacctcgtc tttaaataag ctttgatact tatttttctt
    28141 ccttctcttc tgtctcttcc agcgtttctg ttgtttcagt ttttacttca actgtctcag
    28201 ctggttcttc tgttgtttca acagtagtcg ttgcatcatt tgttacgaca gtccctggtt
    28261 tgaccgtttt gattgctgca cgatcgtact caaggaagat cccttcgcag tctaaaacaa
    28321 ctgtccgttt gtcattgtcg atttctgaaa caactccatg taatccgccg atcgttacga
    28381 ctgaatcacc tggtttcatg ctatctaaca agttttgacg ttcttgctgt tgtttctttt
    28441 gcgaacgtga cataaaaaac cacattgcta atagcgcgat aaacatcaca agcattggta
    28501 atgttcccat ttttttcacc tcactaattc tgtatctaca aaaaacactt tagcagaaaa
    28561 atgctgataa cactagtttt ttacttaatt tttaaaagat tttcctttag aagctttttg
    28621 cgttttcttt attgaacccg tattcttcaa aaaaggcttc tctaaattca agcaaattat
    28681 catccatgat tgcttgacgt acttgtttca ttagattcaa caagaagtat aaattgtggt
    28741 aagaagtcaa acgaatccca aatgtttcat cacatttgat caaatggcgg atataggcac
    28801 gtgtatagtt tttacatgta taacaatcac atttctcatc aattggacgg aaatcatggg
    28861 catatttcgc atttttcact actagacggc cttgagaagt catacatgtg ccatttcgag
    28921 cgattcgagt aggcaagaca cagtcaaaca tgtctactcc acggataaca ccatcgatca
    28981 atgaatcagc agcaccgaca cccatcaagt aacgtggttt gttttcgggg atcaacggtg
    29041 tagtgaattc taatacacga ttcatttctg atttaggttc cccgacagat aacccgccga
    29101 ttgagtaacc agggaaatcc atcccgacta gatctttcgc gctttgacga cgaagatctt
    29161 caaaccctgc tccttggatg attccaaata atccttgacg gtctggatta gcatgagctt
    29221 tcaatcctcg ttctgcccat cgagacgtac gttctactga ttttttcacg tagtcgtaac
    29281 tttcatcgaa tggtggacat tcgtcaaaac tcatcatgat atcagagccc aatttatttt
    29341 ggatgttgat tgctttttct ggtgataaaa acatacgcga accgttcaag tgatttttga
    29401 aatgcacgcc ttcttcttcg atattccgca tatcacttaa tgaaaaaact tgaaagccgc
    29461 ctgaatctgt taaaatcggt tgatcccagt tcataaattt atgcagtccg ccagcttctt
    29521 ctactaagtc ttcaccaggg cgtagccata aatgatatgt attacttaaa ataacgccag
    29581 cacccatttc tttcaactct tctggggaca ttgtttttac tgtagctaat gttcctactg
    29641 gcatgaacat tggtgtgggg aaagttccgt gtggcgtgat caattcccct aaacgcgcgc
    29701 cagtatgttt ttctttcttg attaaacgat agcgaatggc aggttgcgtc attcatttcc
    29761 ctactttcta tataaaatat cttgacaact cccaccatca taatcgtttc aagtgctttt
    29821 tgcaagttcc ctcggcttcc ttctacttta tttaatattc ttttttttat ccttttttta
    29881 tgaataacaa aaaaaagaaa aacattatga cagaaatatt ttttgataca tggtatattg
    29941 gtgttattaa agaaaaggag ggaaaaatca tgcaatcttc tgcagaatta aaacgccaag
    30001 caaaagagag tctaaaagga cgttggggac aagctgtttt actaaatcta atccctacat
    30061 tgattggtat tgctactatt cttcttatta tgattcctat tatcttgttt gccaccacca
    30121 tatatgatgg atcagcgagc gtctcagaag cgacaacttc aggaggcggt agttcaggag
    30181 gcggtggcgg aattatttcc agcatcatta gcgctttgtt catgagcggt atttcttgga
    30241 cttatcttga tattttacgt ggacaaaaag atcagatcga accattcaaa gatgcatttc
    30301 gtggattcaa aggtttgttt atcggcggag tgatcagctt agctgtgctg atctcgatct
    30361 ttacaacatt atggggtttg ctattagtta ttcctggaat cattaaaagc tattcttatt
    30421 ctcaaagcta ttttatttac tacgatatcg tccaagaaac aggacaaaca cctaaagtac
    30481 tggatacgat cactgcaagt cgaaaattga tggatggtta taaaggacaa cttttctggt
    30541 tagatctttc atttatcggc tggcatatct tagcattagc aactgctggt attggttatc
    30601 tatggctcag cccatacatt tctgcaacaa aagcagcatt ttatgaacaa ttgccaaaag
    30661 atatttaaaa gagagtgtga cttgtgaccg agggggtggc aggagaacac cgtttatcga
    30721 gaggcagtaa aagaaacatt cagcccatta gcaaaaagga ggtgtgacaa cattcatgtc
    30781 acacctcctt tttgtatagt tccagtaaaa agaaaatcaa cttagaaaca gttaatcatt
    30841 cctcttcttc tgcttccggt aatcgatgga acttgatcag ttcattcacc gcgattggta
    30901 cgatagataa aatccctacc aagaaccagt gattcaaact gatgtgtact aggccgaata
    30961 gttcttgcgt aaatggcagc aaagcaacag ccgttgtaat agctaatgcc agtaacgcca
    31021 tttctaccaa agctttattg gtcgctaaat tgactttgaa gatcgattgg ctgctgcgta
    31081 cattgaacac atgcagaatc gatgaataag ctaagatcaa gaatgcaaca gtttgaccga
    31141 catgctgact tgcgtctacc catgggctga tagtatcgac ataactacct aaataataac
    31201 caaacaaggt tacgatggtg aagacccctg catttatggc aattttttgc aataaacctc
    31261 gagcaaagat cccttcattt ttcggaatgg gtggctgatc catgatgccg tgttccgctg
    31321 gctctcttcc taaagcaaat cctggaagtc catcagcaac tacattgaca aacagtagtt
    31381 gcacagctgt aaatggtgct ccccatccta acagcatcgc aatcaaaaca ataaagatct
    31441 ccgaaatatt acagcttagc aaaaagttga tagctttacg aatattctga taaaccgaac
    31501 gtccttgact gacagcgtct acgatcgtcg caaagttgtc atccgtcaaa atcatatctg
    31561 cggcactttg cgccacatct gttcctgtga tccccatggc acacccaacg ttacttgctt
    31621 tcaacgctgg tgcatcattc acaccatccc cagtcatcgc tacgactgca cccgtacgtt
    31681 gccaagattt gacgatccgg atcttgtctt ctggcgttac ccgagcatag acagagagag
    31741 ctttgacacg cgcatctaat tcttcgtctg ataattgatg cagttctgat cctgaaagtg
    31801 cttctgacgg atcattcaag atacctaatt ctttcgctat ggcactggca gtcaccacat
    31861 gatctccagt gatcatgact gttttgatgc cagccttttt cgctcgcttg attgctcctt
    31921 tactttctgg acgtggtgga tcgatcattc cgatcagacc aatcaaacgt aagtcttttt
    31981 ccagtgcttc agaagaaata tcttgcggtt cttcgtcata agtagcataa ccaacagcaa
    32041 tcactctcag tgcccgttta ccaaagcgat cattaacgat cgccgcttgt tctacatcgc
    32101 ctgaactaaa gcgcggagca agaacatcga atgctccttt ggtgattgag atgtattttt
    32161 cgcccatttg gtgaactgtt gtcatcattt ttcgttcaga atcaaaagga agctcgttta
    32221 ctcgtggata tttttcttct aattctgcct ttgtatgata attctcttca acagccctta
    32281 cgatggctac ttctgttgga ttacctttga taacaaggtc gtcatcttct tgctcgaccg
    32341 tcacatctgt acatagtgca gccattttca atatttccat cgcgctgttc gtcattgaat
    32401 cttcgatatt cgttacttca tcttctttgc tccatacccg gcggacgcgc atttcatttt
    32461 gtgtcagcgt tcctgttttg tctgagcaga taacattagc ggttcctagc gtttcaactg
    32521 ctggcaactg tcggatgatc gcatgtttcc tcgccatctt ctgcacaccg tatgcaagtg
    32581 tcaacgtaac aataacagtc aaggtttccg gtacagctgc aacagccaag gaaatcgaag
    32641 tcatgaacat ctcaaggagt ggttctcctt gcagttcacc aatcacaaat actaaagccg
    32701 cagccgctaa agcgatcata ctgattcgtt tgcctagctg attcaatcgg acctgtaaag
    32761 gtgttttttg catagtattt tcgttcaaaa gatccgcgat cttacccatt tctgtagcca
    32821 tgccaatggc agtgacgatc gctttcccac gacctgcagc aaccgtacat cctttaaata
    32881 ccatattaag ttggtcacct aatgactcat cttcttcagc aataaatgct gcatcttttt
    32941 caactgcttc actttctcca gtcaacgccg attcttctac acgtaattgt gatgcttcga
    33001 tcaaacgggc atcggcagaa atagcatcac cggactctaa aacaagaata tcacccacta
    33061 ccagttgctc tgactcaaca gtggtcactt tgccgtctcg tatgacagtt gccgtttgtt
    33121 tattcatatc ttgcaaggat tccagtgctt tttctgcgtt tccttcttgg acaatcgcca
    33181 ataccgagtt gatcacaacg atagcgatga tcagcagtcc ttcaaataaa tccccatgtt
    33241 ctgtagcaaa tgcggtataa aaggaaatca ccgctgctac aagaaggatg atcgttgtaa
    33301 aatcggacaa gcttcgaaag aattttttga tcatcgattc tttcggcgcc tcatcgaatt
    33361 tattcaatcc ctgctttttt cgccgttcat ccacttcttg tgaagacaac ccagtatctg
    33421 gatctgcttc tgttaccttc tttacttctt ctattgtctg cttgtattct tccatcctat
    33481 tcctccttta aaatcttcgt acaaaaaaag gtacttattt tactataaca tccttttttt
    33541 atttacttca aataaagggc ttatcgatta tttgttaaga aagcgtaaaa tttaaagtgc
    33601 ttatatttgc aaacgctacc aaaggatgct attatataga tgtaaggaag gaggatacca
    33661 tcaaatagac agaagaattt ctcgatagaa cagtgtaagc aaacaaagtt gttagaagta
    33721 caggtttcac ccagacatgc gtgtagagta caaacctata aatagtgaat gcgtatggat
    33781 gtttggatca cgaagtatcc gaaacaagaa gtaatgcgat acgtaacaat tgaataacgt
    33841 aaacgtctga aaattgaata ggaacaagag atgtttcaaa tgttgaagat gtaacgaaaa
    33901 caaaattttt gtttaacatg aagaaattca acaccgtgct ttgcatgtat gatggaaagt
    33961 tacaatcatt tctgtttatt tgaatccttc cgaggtacaa gaaagccgag cttatcgaga
    34021 gctcggcttt ttctttgtca taaaatcttt gtaaagcttt tttgttattc aaaactagcg
    34081 gcttttcata accttatttc acgaacatcg catctccaaa actaaagaaa cgatagcgct
    34141 cttcaatcgc atgctggtaa gcagataaag tcaattctct tcctgcaaag gcactaacta
    34201 acatgactaa agtcgatttt ggcaaatgga aattagttga gaaagcttct accactttga
    34261 attcatagcc aggcgtaatg aaaatatcag tccatccgct gtctgctttg atttctccat
    34321 taaatttcgt tccaatcgtt tctaatgttc gaattgaagt tgttccgaca gccacgattt
    34381 tcccgccatt tttacgtact tggttcaatc gctcagccgc ttcttccgtc aaacggtaga
    34441 attcactatg catatggtgt tcttcaattt tatctacgct gacaggtcgg aatgtaccta
    34501 accctacatg tagtgtcaga tagactaatt caacaccctt tgcttcgatc tcatcaagta
    34561 attctttcgt aaaatgcaat ccagctgttg gcgctgcagc agaaccattt tctttcgcat
    34621 agacagtttg atagcgatct gggtcttcca gacgttcttt gatatatgga ggcaatggca
    34681 tttctcccaa tgattcaaga atctctagaa aaattccttc atactcaaag tcaatgatcc
    34741 gtccgccgtg ttccaattct tctttcacta ctgcttgcaa tctgccatca ccaaaagaga
    34801 ttcttgtccc aactttggca cgtttcgcag gtttgatcaa tgtctcccac gtatctcctt
    34861 gtgtattcgt tagaagaagg acttctaaat gcgcaccagt atctggtttt tctccatata
    34921 aacgagcagg cagaactcgt gtattattca taactagcgc atcaccaggc tgtaactctt
    34981 caatgatttc atggaaatgt ttatcttcca tctctccagt tttccgatcc aaaacaagta
    35041 aacgagaatg atcgcggtct tttaatggtg tttgtgcgat taattcttcc ggcaagtcaa
    35101 aatcaaaatc ttctgttgtt aacatatcgt cactcacttt ctatcatgtg cttcatcatt
    35161 ctatcatgtt tttcgttctg ttggcaaaat cagcactttt tcacttctat tttttgtttt
    35221 cctaaataaa aaaactaccc tatttgtatt ttttcattgt tttaggcata ctagtaatag
    35281 atagttcttc attgaaaata gaaaaagagg tggcaccatg attgaatttc aaaatgtgtc
    35341 aaaaatttat aaaggtggaa aagtcgctgt agaggacgtc aatctttcat ttgaaaaggg
    35401 tgagttcatt tgttttatcg gtacgagcgg aagcggaaaa acgacgacga tgcggatgat
    35461 caaccgaatg actgatccaa cacaagggaa aattttgatt gatggaaaat ccatccaaga
    35521 aattgatcca gtggaattgc gacgtcagat cggctatgtt atccaaagta ttggattgat
    35581 gcctcacatg acgatccgtg aaaatatcac tcttgtccaa aaattgttga aagtcagtca
    35641 agaagaacgg aataaaacag ctgaaaaaat gattgatctt gtggaattgc cccgtgagat
    35701 gttagatcgc tacccacatg aattatctgg tggtcagcag cagcgtattg gagtcgttcg
    35761 tgcccttgca gcgaatcaag atatcatctt gatggacgag ccattcggtg cgcttgatcc
    35821 aatcactcgt gattccttgc aagaccttgt caaagattta caagagcgtt tgggaaaaac
    35881 gatcgtattt gtaacccatg acatggatga agcgattaaa ctagcaagcc gtatcgccat
    35941 catgagtgaa ggccgtgtga tccaatttga tacaccagaa aatattttac gtcatcctgc
    36001 aaacgatttc gtagaagagt tgattggaga agatcgccta ctacaagcca agccaaatgc
    36061 gacaagagtc ggcgaagtta tgctaaatac agcaatcacg attacaccgg aaaaatcatt
    36121 acaagaagca atcaaactga tgagggaaaa acgtgtagat acgttgttag ttaccgataa
    36181 ttcgaatgta ttaaaaggat ttatcgatgt agaaacgttg aataaaaaac gaggaaaagt
    36241 atccagtgtc ggcgacattt tgaataaaca tgttttttac gtaaaagaat ccgcctatct
    36301 tcgtgatacc ttgcaacgca ttttaaaacg cgggctgaaa tacgtgccgg tcgttgatga
    36361 acagaacaaa gtcgtaggta tcctgactcg tgcatcatta gtggatatcg tctacgatgt
    36421 gatttgggga gaagatcccg caactactga tgttgcagag tcagctactc ctgaagaatc
    36481 taaggaggtc tgacctatgc agcagttttt tcatcagcac ggttcagaaa ttctctcaaa
    36541 aggttttgaa catctttata tttcaggact tgctttgatc attggtatca tcattgctgt
    36601 accgcttggt gtcttactga cacgttttcc aaaagctgcc acgattgtga ttggcttaac
    36661 cagtgccttg cagacaatcc cttctcttgc tttattggca ttgatgatcc cgctatttgg
    36721 cgtaggtaaa ttacctgcga ttatcgcact ctttatttat tcattattgc cgattttacg
    36781 taatacgtac attgggatga aaaatgtcga ttggaattat cgggatgtgg caaaaggcat
    36841 ggggatgact gagttccaat ccattttttc cgttgaattg cccattgcta tgccaacgat
    36901 catggctggt attcgtttag ctgccgttta cgtgattgca tgggctacac ttgcctctta
    36961 tatcggcgct ggtggtttag gcgatttgat ttttagtgga ctgaataatt accaaccaga
    37021 tctcattttg gcaggtacga tccctgtaac aattttagca ctattggctg attggcttct
    37081 aggtctcttg gaacaccggc tgacaccgat cgcacttaga gaggagaatg aagaatgaaa
    37141 cgtatactaa aaatgaccat ggttcttttc tctcttctta tacttgcgag ttgttccttc
    37201 cctggtcttg ccagcaatac agatgaagac accatttcga tcacaggtgg aatcacttca
    37261 gaagcacaga tcttagcaag tctagttgcc ggaatggttg aacattatac agataaaaat
    37321 accgcaatca tcaacaatct ggctactaca actatcaacc atcaagcgat gatgaacgga
    37381 gatgcttcaa tttcagcggc tcgctacaca ggaacagatt taacgactac attgaacctt
    37441 cctcctgaaa aagatccgaa aaaagcgttt gctaccgtga aagatgaatt tgagaaaaga
    37501 tacggtcaaa cgtggttccc gtcctatagt tttgaaaata cgtatgtctt tcttgttcga
    37561 aaagacaccg cacaaaaata ccatctatct aaagtcagcg atctgaaaaa tgtagcggat
    37621 gaattagtag ctggtgtaga tacttcttgg atcaatcgta aaggagacgg ttatgacggc
    37681 ttccaagaaa cttatggctt ctccttcaat tcgatattac ctatgcagat tggacttgtt
    37741 tatgacgcag tcgaagcagg aaaaatggat attgttcttg gctactctac ggatggacgg
    37801 atcgccagtt atgatctagt catgttggaa gatgatcgtc aattcttccc accatatgat
    37861 gctgctccag ttgtagacaa caagatatta gctgatacgc ctcatttaaa agaagcctta
    37921 aataagttag gtcataccat cagtacggaa aaaatgcagg aattgaacta cgaagcagat
    37981 aataatctag tggaaccatc agtagtagca caacgtttct tacaagaaaa ccactatttt
    38041 gaagggaagt gaagcaattg gataaaatga atgtctttca acaatttttc tattatttcc
    38101 aggaaaatgg ctcctatatc tttgcacaat ttatccgtca cttcctgatt tctatctatg
    38161 gtgtcctctt tgcagcagtt gtcgggattc cggttgggat catgatttct aggagacgta
    38221 aattagcaaa ctgggtgatt cgtttggcga atatcatcca gacgatccct tctctagcca
    38281 tgatctccat tttaatcatt ggattaggcc tgggagtcaa tgtcgtgatt gttactgtat
    38341 ttttgtattc cctcttaccg atcatcaaga atacgtatac cgggatgatc caagtagaca
    38401 aaaacatcct tgatgtcggc aaaggcatgg ggatgactgc tagacaacga ctattcatgg
    38461 tagagttacc actctctgtt tctgttatca tggcaggcat aagaaacgcg ttagttgttg
    38521 ccatcgggat aaccgcgatc ggtgcattcg tcggtgctgg tggtcttgga gatatcatta
    38581 tccgaggaac caatgcaaca gagggcacat cgattatttt agcaggtgca ttgccaactg
    38641 cattaatggc gatcatcacg gactggcttt taggtatttt ggaaagacgg ctagatccag
    38701 ccagccgtac atcacgctga tgttattgta aaaaacaaaa gcttctgcga ccatttgttg
    38761 gtcgcaaagg cttttttagt tctgtcattt ttaaggcaat aatccactct gattcttccc
    38821 tccttatggg taaagagttg cttttcttag ctatttatcc attccgtata ctccaacttc
    38881 atactgccaa cgggttcata tctgcatcca ccgactaagt ttttttctta tccgctaagg
    38941 cattttgcca atccattttc ccatcactcg tcatggaatt cataccacat gatctctaaa
    39001 tactcgtctg cttgttcttt gaattgggca tcaattctta catcctttgg cgtggctttc
    39061 atttaagcct tttccatcag tcctcgattg ttcgatgcct tcagctgcat catcaaaact
    39121 ggtgactgcc gtatcggtaa cttcgatcat cttttataca atcgggaact tgccatcctc
    39181 atccttggct aaaaacatat ctagccattc cagcttctcg ccatgggagg tttgcggttc
    39241 ctaaaaccgg tacacgattc ttatggactg catccgtcgc aactagactt ggcgatacga
    39301 tgatccttca ccagaagagc acccccgtaa accaattgat cgatatattg ccaataagaa
    39361 aagacattgg cgtaaaagat atcgatccct cgtgatgcat tgccgttgat actgctattc
    39421 atggccgaaa gcgccacgac tttaacttct tccgtttgag tgacattcat gttcggcaat
    39481 gtcgctttgg atacccgctc tgctaaagga acgacactgg tattgtattt cgtatctgta
    39541 tcttttccaa aagaccatgc caacgaatcc tctgggaacc aataagacga ctccggttga
    39601 ttgtccattg cttttttcaa catacttttg gctgtttctc gataaacgac atttccaatt
    39661 gtcttcgcct cactttggcg ataatcgatg gtcgttgcca ctgccaacac taacaacgat
    39721 gctccaattt tactgatttt ccttgtcaca cttcttcctc cttgttttac ataaacccgt
    39781 caacattcca ttcctaaact caaacaatga cccttcaaag gtggagatat aggaacaaat
    39841 taaagaaatc atgcaataaa tccaagaagg ttggttttag aacaaaaaaa gagtctcctt
    39901 tttggggaga ctctttgtta actatctaaa aaggttggct cttctcactt cactcataat
    39961 gtgtccaggc agaataaatt tctacaactt tattttcctc atcaactttg taaaccactc
    40021 gatgctgtct attcagcctg cgtgagtatc tgccttcatg tgtaggtctc agcttttcaa
    40081 aagactgcgt gggcatatat ggatcttcct tcaatgtctg aatcacttct tcaaattgtt
    40141 tctttaaatt cgtttgcttg atttttctta aatccacttt cgcagagttt ttgattgcga
    40201 ctgtatagtt actcatcaaa gagcttccca atcaatatca tcgatattcg taaagctact
    40261 gtcgtctttt tcgcggtctc gtactttatc taaagtacct gtttgctcaa gaaaaagggt
    40321 ttcttgaatc gctctccagt cttccagccc aatcaataca gcattgtttc cactacgatc
    40381 actaataatc tcgatttcag tatgattttc atttacctct ttcaataact gataaaaatt
    40441 tttacgagca gtgctaggat tcatcgttgt attagccatt gtctctcctc ctttttctga
    40501 tataattata gcgtacttga ttaagtacgt caaaaaaata caataaagca cttaaattca
    40561 gcaaactttt cctctttttt acatagagaa aaagacccct ttttagggag gatctttgtc
    40621 cacgctcact tcttactcct ttacgactag cggtagccaa acgtaaagta attggtaaca
    40681 acgtatcatc tttagcaaag gtcgaatcca aagcctgtga gtctatgcaa caacaccaat
    40741 acacgaaggt tcctcgttgc agtgtgactt gattgatatc ttgaataacc tgaggatacg
    40801 cacgaaagat ttgtaacggt tattcaaaac tgattttggc cgtcaagtct tctactgcct
    40861 caaaaatgat tgcctctttc gtctcctgtc attcatgttc actatcgatt tgatacttgc
    40921 ttagaccgtt gggtttgtga atcaccaatt aaaaatggca ctgagttatg gtaacaaaaa
    40981 atggtcactt gacgaggctg agattcctac ttatgaagac acatggcact taagagtcga
    41041 ggtaaaggaa gaagctgaaa atataggagg ctgtacatta tttggcaaag gattcggaaa
    41101 ttatgatcaa gacatcaaaa tcaaaatgtt ttacagctaa ataggaagaa taataacatt
    41161 tcatacgctg ttcccatctt taatggctta tagagggcac ctttagctga gaataagaca
    41221 aaacagaccc tctagcttca attaagagct agagggtctg tttttgattt taaaacttgg
    41281 tttatttctt caaatggtag ctataggtgc tgacaacgat attttcacgc caagacaatc
    41341 gcaatcttaa ccgcaaactt gtttggttat ggagaatatt ctgccagcgt ctgtttggta
    41401 caaattgagg aatcaacaca gtagttgtat agttttgttt cgctgcattt ttacttacga
    41461 tatctacata acggataatt ggattttcaa tcgagcgata agaagagtgg acgattgaaa
    41521 aacggacatc tgggaaatgc tttttaaatt ctgcttcgat ttctttttct ttttcgacat
    41581 cttcgtctag cgaaacatgc atcgcaacga cataatcacc gatcgaacgt gcgtaattca
    41641 acgcaccgat atttacccgt gtcacattcc cgactaatac aagaacggta ttcccgtcat
    41701 aatcatgtag ttttgcatca ttttctaaac gaagctgttc tgctactttt ttataatgat
    41761 catggatctt ataaaaaatg aacataacga ttggcataat gatgaagaaa ggccaaatgt
    41821 cccctaaccg atagacaaac aaaatcgcaa tgattgcata tgagatgaac gcacccgtaa
    41881 tattggcaat cgatttgctt aaccatcttt ttccttcttt tttccatttg acgaccatcc
    41941 ctgtttgaga taaagcaaat ggaatgaaca cgccgataga gtataacgga atcaagcgtt
    42001 ctgttgagcc atggaaaata aacagcaata cgatcgaacc tagcgctagt gtgataatcc
    42061 cattggaata gcctagtcga tccccacgat cttgatacat gtgaggcatg aatttatctt
    42121 ttgccagatt gtatgcaaga actggaaaag cagaaaaacc ggtgttagca gcaactgcta
    42181 aaatcagcgc tgtagcaaat tgaaggacgt aatacaaaat accatgtcca aagacagctt
    42241 taccaatttg agacaaaaca gtgacttctt tttcaggaac gatcccatac caatagttga
    42301 taaatgtgat ccccacgaag aagaaaccta agatcaatgc catcatcgtc aatgtagcag
    42361 cggcattttt tgctcttggc ttcttaaaga atggtacagc attactaatc gcctccaccc
    42421 cagttaaaga ggaagaacca gaagaaaatg ctcgtaaaat caaagcgata gaaacacccg
    42481 gcacagccgc tcctggaagt gcagtagctt gcaatggcac agcacctgtc acgatattat
    42541 ataaaccaac aacgatcagt aacgagatca caaggataaa tgtgtacacc ggaaataata
    42601 ggaacgatgc agattccctc agcccacgaa gattcagcat catcagtagc aaaacgattg
    42661 tcacagaaat agcgacttga tgaccgtaga gtgctggcac cgctgatgtg atcgcttcag
    42721 cacctgctga gacagatact gctactgtca acatgtagtc gatcaataaa gagccaccgg
    42781 aaatcaagcc agcattcttt ccaagattct cactgctgac gacatatgct cccccgccat
    42841 gaggataagc atggatgatt tgacgatatg atagcgttaa tgaaatcaat aaaataataa
    42901 caaaagcggc aatgggtagc gaataccaga tggctgcagc agacaaagcg actaaaacga
    42961 caacgatttg ttccgtacca tatgcaatag atgataacgc atcagacgac aataatgcca
    43021 aagcagcaaa tcgggttaat ttgtgctcat cattttcagc agattttaaa ggcttaccta
    43081 ctaacaacct ttttaagtaa tccaatttct aaactccttt acacacaatt ttacttcaag
    43141 ttttatagtc gaaaatttat agtaaacaag atgttatagt acgctcactg accttaaaag
    43201 tcaataaact ttaagaaaat aattggaaaa aaacagaaaa atatcaagcg ctttttcaaa
    43261 cgctttaata cagcaaaaat ctaacatttt tttatgggct ttttctttga attctataat
    43321 aaaaggatag aacttgactt agaaaatcaa gttctatcct ttttgatatc ttaacttttg
    43381 gaagagagat gtaaggctgc tttctaccca tcattcttac tactcgaagc atagcgcagt
    43441 tgtcacaacc tcttgataaa cggtgtttaa aagcttgcat ctgcggtaat aagcccaacc
    43501 aaattaaaaa cataagaagc tgtttttatt tggtcgttct tattacttga tgcagagcag
    43561 cttttttaca acctcttggt acacggtgtt caatcagctg accctcggta ttagctcaaa
    43621 aaaacggcaa aatatgagga actatttttc catttttttc tctaatactc aggtcaaaac
    43681 actgatttca caacctcttt ttttaatgaa aaatatggct ctcatgcgcc gcttctttga
    43741 atttcgtcat tttttcttcg atgaacggat agattgccgt tcctacgatt ccaaagacaa
    43801 caaacaaacc gatcatgatc cagattgctt tcgtagcatt tggccaataa attcctcctg
    43861 cagattcccg taacaagttt accgcatgag taaatggcaa gaacggattg atcatttgga
    43921 agaatttccc tgagacttgg atcggatagt tcccgcctcc gccagagatc gacagtacta
    43981 agatgataat agcgatccct ttaccgacat tatcgaataa tgcagccaag acatagacga
    44041 tcatcatgaa cgctaaggcg atcaagacag caaatgacac gctgtagacc ggattttgga
    44101 catctactcc tagtaagaaa atattcccta atgtaacgat caagctttgc gcaatcgcca
    44161 ttgtcaaaaa tgtcagcata cgagcaacga attgttctcg tttcgtaaaa ttgtttcggt
    44221 ctttctttcc taaatagtat tctgtcgtag caacacttga aagaagaaca gcgccgaccc
    44281 acagacatag tgcagtataa aacggggtgc tagctgaacc gttatttgcg attggataaa
    44341 gcgcattggt ttgtagctca acaggttgtg taaagaagtc actttctttt gttgcgtcta
    44401 gtttcaataa tttgatgact tcgcctagat cgacttcttg ttcgcctttt cggatcgcgt
    44461 ctgctgcttt ttggatacca gctttgatat ttggccagtc attgttgatc aagtccgcag
    44521 cagcgttcac agctgtttcg acttctggca ttttttcatt tactgttgtc aatgtaccgg
    44581 tgatttcatt ttttagtgct ggccaatcat tttggataaa atcagcggcc aatcctaatt
    44641 tttgctgaat gatcggtaat tcattgttgt ataggtctgc cccttcattg atgccattga
    44701 cgatggtatc catatttcca ttcagcattg tattggcatc atggatttct tgtccaattg
    44761 caggcatttc tttttgatat ttttctaaaa ttgccactgc attcgttaca gttgctttcg
    44821 ttgagctgag aagcgaatca aagtcgatct ggtccgcttt gctcagtgcg ccttgtgcag
    44881 tcccaatcgt atcgatgact tggtctagta gagaagtgac agtggaactg atttgacctg
    44941 tattgatacc agcaatgatg ccattgatat tattaacaac ggcatcaatt tgatctagca
    45001 attcatcaat agccttcgtg tcttcatttt gaacagctgt gttcaaagca gataggcggt
    45061 tttgcagatt gcttagcaag ggttttaatt gatttagctg atcaataatt ggctgtaatt
    45121 tcgtatttcc agcacttgtt tgcaatttag tcaggaactc gaccagttta tcgattgcat
    45181 tttgttgttg agatattccg tcaataaagc cgttcaatac attgctgatg tttttctttt
    45241 catcatcagt cagcttacca tcttcaatag ctgttcttac agtatctatt aacgaacctg
    45301 tcgttgttgc cacttgtcca attgacttca atgtaacatc tacactgttt gtgatgcttg
    45361 gtatcgcatc tttcagctga gaggcacctg attttgtttg gtttgctaga tcacttgcct
    45421 gattttctaa atttttcaca tctggcaaga tatcttgtac ttgttggatg atcgtcaagc
    45481 cttgttttgc ttcatcgatt ccttggttca ttgtctcttg gatcgaagca aaatcgccgt
    45541 cgatctctgc tagttgctta ccggcatttt ggatctctgg gattttttct tgcaaatcaa
    45601 ggatgatttt tgcttgatct ttcaactcag gcattttgtc attcaatgca acgacttttt
    45661 cacccatctc atctacttta gggatgtaat ccacgaattc atttgcttta ttcagttttt
    45721 ccttgatttc aggtagttga ctttgtaatt cgaggacttg ttttgtgtag ccgtcgatcg
    45781 tgtccaaatt ttcatctgtt gataaaatca tatctttaac tttattgata cttactaggt
    45841 tcgtatcgat gtcgtaacct atctcattga atactttcaa taaagtcgaa ctggctgttt
    45901 tgataaattc atttgtgatt tgcgattgga tcgaacttgc tcctttatcg gtgattttcg
    45961 gtgcaatcgc attgattttt tcatttaccg tatattcgat ttttggtttc ttgatatcac
    46021 cactagtaaa actcagcaga tcttctgaga aatcctttgg caagtaaata cctgcgtaat
    46081 actttccgga acggactccg tcttctaatt gttcttttga atcaacgaat tgccatccta
    46141 attgtttatt tttatgaagc gattcgatga cttgctcccc aatggccact tctttacctt
    46201 gaaactctgc tggcttgtct gcactgtaaa cagcaattgg cagctctcca gtatttccat
    46261 atggatccca taatgctttg atgttaaacc acgcatatag cgaagggatg atcatgatcg
    46321 cgatgatcag aagtgttgca atcgggtttt tgaaaatccg tttccagtca agcaaatata
    46381 atcgaagcgt atttttgatt gactgcatag ttctccccct tcttcttttt tcagctgaat
    46441 tactttacca tgtatttcat acttttttca atcggctttt ttcaaaaaag tcgaattttt
    46501 ggacatatca cggcaattgt ctcattgtaa tctcttacat attgagaaat aattaaggat
    46561 tacagccttt actttatcat gaaataaaag ggaaagataa ttttatgcca aagtttttat
    46621 ctattatacg tatacgcaaa aaagctaaaa cattttttgt ctttgcccct acaaaaatgt
    46681 ttcagctttt ttcgtttttt attcctgtat ttcttatttt tcgaatgaca ggatgatttt
    46741 cccagcagga ggatgtcctt caactagctg atgtgcttgg atgacatgct taagtgaagc
    46801 agacagattc attgaaataa aaacatgaaa ggctcctttt tggtaggctt tgattatgcc
    46861 agcaaaggct tctgcatcta gatattcctt tcttggaaca aacgattcat aaaagccttc
    46921 ctttttttgc cgcaaatcta gatctgggag gtcatttaat gcaacatacc tgccgcctgg
    46981 tttcatgatc tggatgccgg tttctccttt gatacttcct ttcgtcgcat cgattacaag
    47041 gtctgcctga tcagcaaatt gcagacctgg atttgtttta tcataagcag caaatgctga
    47101 agctcctaat ttttttacct tttcctcatt tttactggat gcactggtta agattcggat
    47161 tcccttttca tggagaagct ggatcagact tgacccgacc gcacctgatg ctcctagtat
    47221 cattacagta tctgtcggct ggatttccgt caaatggttg attagattat aagccgtaat
    47281 tcctggcgtg accattccgg ctgcttcttc ccaactcatt ttatctggaa tttttgctac
    47341 ttttgctgat ggcaacacga cttcttctcc gtaagtcccg ccgactgcat ggacagctac
    47401 tcgatcacct acatgaacag ttgtgacatc tgaaccaatc tctgtcacaa taccagcgcc
    47461 atcattacct ggtacataag ggaatttcaa tgttcgtatc tctttcattt ctcctaaacg
    47521 caaggcaaca tcataaggat tcacactgaa tgcttttatt tctacacgaa catgtccaga
    47581 accgacttct ctgggatgag catcgatttc ttcaaaaaca tcttgtgctt ctccgtaacc
    47641 gttaattgca aatcttcgca tggtcaccat ctcccttttt ctttaagttt acgtttatgc
    47701 ctttattttg acaaaaaaaa tgtcttttcg ttttggcgca tgattcaaaa caaaatagtt
    47761 gtcttttttc gcgtaacgtg ttaaattatt tatctaaaag cgtaaagatt acgatttacg
    47821 ctaataaaaa ataattggag gaatttgttg atggctaaaa aatcaaagat tgccaaagca
    47881 aaaaaacagc aagaaacgat tgaacgctat gctgctttac gccaggaatt aaaagcgcaa
    47941 aaagattacg aaggcttgcg taaacttcct ttagatgctc gtccagaacg attgaaaaat
    48001 cgtgatttaa tcgatggacg ccctcgcgga tacatgcgta aattcgggat gtcccgtata
    48061 aaattccgtg aattagcaca taaaggtttg attccaggag taaaaaaagc cagctggtaa
    48121 tccaagtctg gctgtaatgt aaaggaggag ggcgcatgga ccactccttg gatcatcaaa
    48181 aaagatacgt tcgcttcttc tagcagaaat gctggtacta gaagcagacg tatctttttt
    48241 tacgcacagc tggtcctttt ttatatgtaa aggctgcatg gttacttcgc tatatttatt
    48301 tagtaacagg agtcagtgct tcgataccca cactaatttt caatgctcgg tcaacttctg
    48361 ccataatggg tcgatccaaa tggcagacct tttctttcaa tcttgattta tcgatcgttc
    48421 tgatctgctc caacaggata acggagtctc tttctattcc tgttccagta gctttgatcc
    48481 caatgtgagt cggaagctta ggtttagcca tttttgccgt tatggccgca acaatgatcg
    48541 tcgggctaaa atggttacct agattatttt gaataaccaa aactgggcgt gttccgcctt
    48601 gctccgatcc cacgactgga gaaagatcag caaaataaat atctcctctt tttaccatag
    48661 gatcctcctt attcttgata ttctcttggt atccgctgtc ctaatccgca agccacttca
    48721 tagtggatcg tacctaattg atctgctata tcctgcatag tgatttcttt gtctgcattt
    48781 ttgccgataa gcgtcacttt tgttccgaca ggaaattctt gaggcaatcg gatcatcagt
    48841 tgatccatac atacacgccc aatcgtttca cagtagttcc cttctaccaa tagagaaaaa
    48901 ccctgcatct ttcgtggcca gccatctgca taaccgatcg gtatcgttcc gatccactct
    48961 gcttcaggag tgatatatgt ttctccatag ccgattcctt cacctgctgg gagttttttg
    49021 acttgaatca attcagaaac cagctcaagt gctggctgca atggataaac ttccggtagt
    49081 gcgtgcccag agggattaag tccgtacatt gctactccat aacgaatcat attgccgatt
    49141 gtttcatcat gccataaagc cgttgcacta ttgctgacat gtacatatcg aggaagttcg
    49201 ggaagttttt tcagcacttc tataaagcgt tctttttgca gattccaata tgtatcatct
    49261 gcctgatctg ctgtagaaaa atgggtaaat aaaccttccc attctaatac acgactttct
    49321 ttgatgaatg cagctgcctc ttttacttct tcaggtgtac aaaatccgat acgacccatc
    49381 ccagtgtctg cttttagatg aatcgaaaga ggcgtctcta gcttactttt ctctaaaaca
    49441 gcagctgctg cttgcaacca ttcccgtgta cctgcagtta ctgataaatc atgagcaaca
    49501 gctacagtca gtgcgtcgta aggaaccata ttcaagataa ggatgggctg agtaaatcca
    49561 gcttctctca actcgactcc ttcatctaaa tttgaaacac aaaagcccga agctccacct
    49621 gcaactgctg cctcagctgt ttcaatagct ccatgaccgt atccgttcgc ttttactact
    49681 gcaaacaatt cttttccttg cggaagtctt gcaacttcat ttgctacatt ttcagttata
    49741 gcttttttat gtatcactgc tttcgttggg cggtgccaag cgacaaccat cgtttttcct
    49801 tctttctagt cttccaaaat aatttgtgca aaagctgttt catttgtatg agtaatactg
    49861 acccatacat tgccttcatg aggtgaacgc gtcacaacag gctgaccatt ttcatttttt
    49921 aaaatctcga catcttgaaa ggtaactttt ccgatcccag ttccccaagc tttagagaaa
    49981 gcctctttgc aagcgtaacg cccgcctaaa aattctactt ggcgatgaaa aggcaaggac
    50041 tggaatagtt tcatttcatc agaggtcaag attcgtgcaa tgaattttgg tttttcttcg
    50101 atcagccgag tgatcctagg aagttcgact gcatcgatcc caattccttt tatcatatgc
    50161 ttttctcttt tcaataaatt tagaacactc tcattctacc aaattataac cattttgcca
    50221 caaataagtc cacaaataac aaaaatgaaa gtttctctta aaaaagagaa actttcattt
    50281 tatgtttaat cgttatttga acggattaca aatccgcgtt ttttatcatt gtgacgttta
    50341 ccgccatctt tttggctgtt attatttttg ctataaccgc cttttgattt gtttccacga
    50401 taattaccgc cgtcacgacg attacggttg tttccgccac cacgtttgcc atttttattg
    50461 tatccttttt tctgcattgg caatgggcgt tctggtgtga tcttcactgg cactgcatca
    50521 gctggatctt ttgctgtcgt ttttagcaaa agtgcaacta aatcttgtgc agaatattct
    50581 tctaataatt tatctgctgt ttgcaggtat ttatctagac cattttctgc aagttttgtt
    50641 tcgatttgtt caactgcagc acctaattga cctttgaatg cttctttttc ggttggtgga
    50701 cgtaaagtcg tcatccgttt tttcgtcaag ttttcaatca catgcaagta gtccatttca
    50761 tttggtgtaa cgaaagtcac agacataccg ccttttccgg cacggcctgt acgtccgata
    50821 cggtgaacgt agctttctgg atcttgaggg atatcatagt tgtacacatg agtgacacct
    50881 gaaatatcta atccacgtgc agcaacgtct gtcgctacaa ggatatctaa atgaccgctc
    50941 ttaaatgaac gcaatacgct cattcgtttt tgttgagaca aatcgccatg gattccttct
    51001 gcacggtaac cgcgtgcttc taatccgcgt gccaattcgt ctacacggcg ttttgtacgt
    51061 ccgaagacga ttgttaattc aggtgtttga acatcaaaca agcgagtcat gatatcgaat
    51121 ttttcgtatt cttttgcgcg gacatagtat tgatcgatca agtcagctgt catttctttc
    51181 gctttgatct tcacatgatg tggatttttc atgaatttaa cgccaatatt cttgatagct
    51241 ggcggcatcg ttgctgagaa aagtaatgtt tgtctttgat caggaacttg tgaaatgatt
    51301 ttttcgatat cttccaagaa gcccatattc aacatttcat ctgcttcatc caaaactaat
    51361 gtttgaacgg ttccaagttt caatgtgtgg cggttaatgt ggtcaagcat acgtcctggt
    51421 gtacccacaa cgatatgtgg acgatctttc aagccacgga tctgacggcc aatatctgct
    51481 ccgccgtaaa cggcttgtac acgtactttt ttgtcgcgcc ctaaacgata taattcttct
    51541 tgtgtttgga tagctaattc acgtgttggt gcgataacta aaccttgtaa ttcgtgacga
    51601 tctggatcga ttttttctaa cattggtaat ccaaatgcag ctgttttccc tgtacctgtc
    51661 tgtgcttgtc caataacgtc ttttccagct aatgctagtg gaatcgtttc tgcttggata
    51721 ggcgttgctt cttcaaaacc agcgcgttcg actgatttca acaattctgg tgataattct
    51781 agttctttaa atttcaaatg aatcctccta tatggttgtt aactgaggat gtagcttttt
    51841 tgctaccccg tcgatttgtt cggtcaaagt gtattgtttc tttttgacag tggccacgca
    51901 cgtttttatc cattcttagc ccctgtggca ccaccgaaaa atcactttgc gaagtttagg
    51961 cattagaaaa gccaaacggg tcgcgttcag ctttatcatt attatgacat ctggcttcaa
    52021 caagttgttt ctatggcaaa accagtccaa tttctcttca tctttcggca ataggttatt
    52081 ctaacatagt ttttcgtttt ctgcaagttt acagattttt atttcatttg ctgaagttgt
    52141 tctaccactt caaataagcc catgctgttg ctgcctttta gcataatact atctgttgct
    52201 tcaagatttt gtttgatagc atcaatcaat ttattctttt ctttttcaaa atagaacaca
    52261 ggtagttggg ggtatttttg gttcaattct tcttttagtg catgcatttg ttccccataa
    52321 aggaaaatca tggcgaattt ctcaggatcg atatgttcac tcatttgcgc atgcatattt
    52381 aaagactctt tccctaattc cagcatatct gctaacacag cgattctgcg tccttttgtt
    52441 ggcagatttt taaaagtatc taataccagt cccatggctg ttggatttgc attgtagaca
    52501 tcgctcaaaa tagctgcacc atttcctgcc gttagccatt cggttctgtt ttgagtgata
    52561 gaaacatggg cgagcccttg gcgtatctca ggtatggaca gtccaaagaa gcgcccgatc
    52621 gtatacgcaa tcaaagcatt cgttacatta taacttccag gcagcgggat cgtaaatgtt
    52681 tctccttcta ctacaaaatc ggtttgtgct tttccttttg ctgtcacttc cgcatgaaca
    52741 tcgccatttc caataccgaa tgttgtgact gtttgtacta atgttgccgt taaaggtgtc
    52801 agcaacggtt catctgcggg cacaacgagt aatccgtctg atacaagtcc gtcagtgatt
    52861 tccattttgg ctttagcgat tccttctcgc gacccaagat tttctatgtg tgcttcaccg
    52921 atcattgtga ttgctgcagc ttttggttga gccataagtg aaagttccgt gatttcattg
    52981 gcgtgatcca tgcccatttc caaaacgatc ttttctgtat cttggggcat gtgcaaaatc
    53041 gtgtaaggaa gaccaatatt attgttgtaa tttccttgcg tcttatatgt tttgtatttt
    53101 tcagacaaga cagacgcggt tagatctttc gtggtggttt taccattgct tcctgtaatt
    53161 gcaacgactt ctgcgcctac tttttccaag taataggttg ccaattgctg catggctttc
    53221 aaaggatctg ctacaggaat aactggaaaa ttttttggag cttgttcaac aggcaagctc
    53281 caaaatgaag cagatgctcc gtttgtgatc gcttgctgga taaattcatg tccatctcgc
    53341 gtaccagcaa gaggaacgaa taaacttcct tcggttatct tccggctgtc aaattcgaca
    53401 ttggtaatct ttgtcagtgc agagcattcg ctgcccacgg cttgtgcaat ttcttgtatt
    53461 gttagattca ttgagatctc tcctaaaaaa ggttgtgaaa aaagcgtttg gcctaaacgg
    53521 cgggttcgca tgactctcac ttccaagtaa atttctctat tcgtatttag aagctagaat
    53581 gaacgcggtt acgcaatcac tccagcctct tctttatttc tctttattca tttttttcaa
    53641 aaaaagattg acgctgatgg tatcgattca ttcctaactg gatcagttct tcaatcaaat
    53701 caccgtattt caagcccata ttttcccata agagtgggta catactgaac tccgtaaatc
    53761 ctggcataga gtttaattca ttcaggaata attcattttt atttgtcaaa aagaaatcgc
    53821 accggctcaa tccgcttcca cctaacatcg tgtaagctaa cttcgcgtac tcttgcgctt
    53881 tttgataaac ttcttctggc acttcggctg gaatctgcat ttcgatttta ttattgatat
    53941 attttgcttc ataatcatag aatgctacgt cttttacgac ttcaccaggc aaagtcgtcc
    54001 gaacgtcttc atttcctaat acagcaactt cgatttcgcg cgcttcaatt ccttgttcaa
    54061 cgattgctcg agaatcatac tgataggctg ttgctaaagc attttgcagc tcttctcggt
    54121 tttctgcttt tgtaatgccg acactagaac ccatattcgc cggtttgaca aacatcggat
    54181 aaagcaaaga accttcacat tgatcaaata cttttttagg attttctttc cattgattct
    54241 taagtactgg tacataagga acttgcggca caccagcagc ttgtaaaata tacttggtca
    54301 tgattttatc catggcacat gcactggtca atacgcctgc gccgacataa ggcatattca
    54361 atgtctctaa gaagccttgg atcgttccat cttccccgtt tggcccatgt aaaactggaa
    54421 aaacgatggc tccttcttct ttgatttcgc ccggattgat cacttttcct gtaaagcctt
    54481 cctctgtctg tccacttggg tcccatgaaa gatgcaagac atctttgctg gcaggttttt
    54541 ctgttagtaa tggacctttg acccattgtc cttcttttgt aataaatacg agttgaactt
    54601 ggtaataatt ataataaatg gcatttaaaa ctgaaaatgc ggaaagaatg gacacttcat
    54661 gctctgcgct gcgtccgcca tatagtaaag taatcttcaa aagattgtcc tcctgtattc
    54721 taaatcgttc agtgatttac tctcatattt tagcacaaaa caaaaataaa cgaataactt
    54781 atttataaaa aaacgagcca gcttctaaaa gaacgagcgt catttatttt ttgtcagcta
    54841 gattatttgt cccgtttttt ataaaaagtt atgataaaga aaaggaggga tgatgatggc
    54901 gcaaacaaat ccacgcagcc gcttggcaga aatcattcga gtgttcatca attacaatgt
    54961 agtgccaaac tttgtacagc aaaaaaatcc cgaacaggta aaaaaagcct ttgaagaact
    55021 aggccccacc ttcatcaaga taggacagat gctttctgtt cgagaagatt tgctttcttc
    55081 tgccttcact caaacattca aaacattaca agatagtgta cctagcgaca cattttcaac
    55141 ggtcaaaaag acgatcgaaa cagaactttc tctttcatta tcagatatat tcgatgattt
    55201 ttcaaaatcg ccttttgcct ctgcttctat ggggcaggct catcgtgcca agctgaagaa
    55261 cggtgacgcg gtagtcgtta agatccaaca ccctaacatc gccgaagaga tccgacttga
    55321 tcttcaacta tttgaacgag cgatcccttt gatcaaatac attcctgaaa ctagcgtagt
    55381 tgatctaaaa ggggtactcc aagaagtaaa acgttccttg atcaatgaaa tggacttctt
    55441 aaaagaaagt caaaatggcg aacaattcta tcaaaagaac aatggctgga aagagatccg
    55501 cagccccaag atttatgacg ctttttgttc gaaaaaagtg atcgtgatgg aagaaatgtc
    55561 tggtaaaaac ttgaatcatt taatgaacgc cgaaaacaaa actgaaactt ttatcactgg
    55621 aattcaaaac aagcagctga aacaagaagt tgcaaagctt ttagttgaga actttatgaa
    55681 acaggtgttt gatgatggtt ttttccatgc tgatcctcat ccagggaatc tgctattcca
    55741 tgtactaaca aaagaagaac agacacaagc tagccgaaaa actgaaacag tccatgaaaa
    55801 agagttcggt tcctttgctt ttcgagcctc cacttctgca gaagaccctg ttgcgccata
    55861 taccatcaac tacatcgatt ttggtatgat ggggcatctt tctgcaggac ttaggcaaaa
    55921 actcacacaa gccgttttag cgctgtatac gaaagatgct tatcgaatcg aaaaagcggt
    55981 ccttcgactt tgtcagcaag aaggctcgtt tgatgaaagt cggttccacc aagaactgac
    56041 aagttttctt gaacagtatt atgattctcc tattgatgaa atcaacttgc aagaagtatt
    56101 cacacatgtc gtgacgattt gtcatcaaaa taatctgcag ttcgatcgtg atatcacgct
    56161 tttgctgaaa gcatttggga cattagaagg ggtgatccgc gtcctcgatc ctgaagtttc
    56221 cctcatggaa gtcgcttcgc cttttgctca acattatttt ctcactcatc tggatgtaga
    56281 agatacattg aaacaaagcg gattagactt attggaaggg atgaaggctg cgcctaagat
    56341 ccctcaacag ctccaccatc tattagaaat gtggacttcg ggacaaggaa aagtcaattt
    56401 ggaattgaaa aagcaagaca aattattgag caggatcgaa agtatgatca atcggcttgt
    56461 tttcggtatg attttagctg cattgatcgt agggtcctcc ctgcttgtcc aagcagcacc
    56521 tgtagaaaac gcagaggtcg tttccttatt agggatattt acgtatgcta ttgccgcatt
    56581 cgtcattatt tttttggcaa tcgatgcatt gatccaaatg tataagaaga ggaaaaagta
    56641 gaaaaaggtt gtgacagaaa gaatcagctt caagaaataa gaaggggttt tacataaatt
    56701 gtttctcaaa tttttgtgaa aattcggctt atttttcgaa gaggctactt ctgaaacacc
    56761 gagaataaaa aatgtgaaaa agctgttctg cacccagtaa taagaacaat caaaaaggga
    56821 acatggaaca catttatcct gtttccctgt tccctttttg atgtattcga gcataaataa
    56881 aataccttcg ttacctacta tcttctgtac ttggtaaacc ttagtcaatt gcctttttta
    56941 acgcttgacg aaaagacata tgatctttct ccgtaaaggg ttttggaccc tttgtcctta
    57001 tgccagcttt tcttaacttt ccactatgat aacgttgttc tagaagcgtg ccgatattcg
    57061 cttcgtcaaa ttcttttcca gagtgatgga acactcgcac acccttcggc aatacaagtg
    57121 aagctaaacc ataatcttgc gtgatcaaaa agtcattctt cttaaccata ccgacgattt
    57181 tataatccgc actatcagct ccgcggtcta cgtagacgat ttggacatga ttagcgtatt
    57241 ctttggtcgt ataatggtcc acactggtca cgataaccac gtcaagacca taggattctc
    57301 ctaattttat gacatcttct tttactggag aaccatctcc atcaatgaat agcctcattc
    57361 tttttcgcct tcttccataa atgataaaca gttactaatc cgctcagtaa aagaccaaca
    57421 ttgatccatt ttgccaagat aagcagttgt acactttcta tcggcactga ttcatggttc
    57481 agcgtgatca ataatagatg gattggctct cccatttctt ttgctaaaac aaacaaaagc
    57541 gtcatcaata aaaactggtg gatcacactc cctttatttt gagtagtata cttgacaacg
    57601 atccggcgat ccattggaat agctgtatca gtttgataat attccttatt tagccagctg
    57661 cctgttacta cgtgccagaa actaagcaga aagacaccta tcgcaaaacc atttggaatc
    57721 aagaggacca ataaagaaga actcagtcca agcaattgca tagccaatgg agaccatgtt
    57781 aaacgtttca aaatccatgg tccgactatt tttgctgcaa tcaagcctgc tgcataaggc
    57841 aaatacataa aaatcgaaag tttttctaat ccgtacagta tgccaacata aaaactgcta
    57901 aataaaaaaa ggaaattccc tagcattcca tttagaaaag taaacagatt tagccagctt
    57961 ggcaacttcc attccttctt ctggtgtcct aaaacaaaca cgaacaagat gaacagcagc
    58021 aagaaaccat aaatagcaag atcaaaaagc ctttcatcga ataacaatcg ggcatttctc
    58081 aaaagaaaca ataagccaaa gaatatcaaa aataaaacaa gctctcgcgt agctaccaga
    58141 tttcttttga tgtctttgaa atccagttcg taacgcggat aatgactaac cgtatggtag
    58201 gccatgacgt aaaaaagtgt ataaatagta aagcttgctg caatctgagt cggtgcaggc
    58261 aactcaatcg cttgatacag gagaaatagc cagatagctg caaataagta ctttttccca
    58321 tccatattga taaaaccttg cgtcttttcg tgaaaattga ccgtggtatt agcaggtaca
    58381 agccatgctg cactcagccc tagcaaaaca cttgaaaaat aaaataaagg aaaataaaat
    58441 acgcctaata ttccaagcaa tgaaccagca ccaccaatca gcagagcgat catcagcaac
    58501 gtgtaactat ctagaccaaa tcgtagactg ttgactaaaa atagtccagt catccgaaag
    58561 gcataaaaca gcgtaaatgg caaaatcgtc agccaattat gcgagtctgt tagtcccaaa
    58621 aataaaagat aaggaataaa aataaccgtg ttacttaaga taaagggcgt tgtttgtgta
    58681 aaattacgcc caaatcgttt gagtttttcg aacatgacaa tggctcctta aacagtctta
    58741 taactaatct gctcttcgat tttagcatta aaggggaaat aaaccaattt tacagaatat
    58801 attcttgtaa aaaaaaatac agaaagaagc ataagcttct ttctgcattt ttacggtact
    58861 tgattactca agcagacaag cccttctcca caaaagtctt gcccgacacc cctgcatccg
    58921 gcaggtgata aagatagaaa tcaattatcc tgtgcctcca aaatcaatta ggagctctgt
    58981 aaaccagagt ccttctcgac ccgtcgcata aatttacttt aacacagttc ctatgtttat
    59041 gcgagagctt ttttcatttt ataatcgacc atttgaaatc cttgaccgat atctgaaata
    59101 agttcttctg taatctcaaa tccttcatgc ttataaacct cgattgcttg atgattcccc
    59161 tgattcactc gcaaaaagat ctctctttcc tttgtttgcg cagcaagttc ttcataccag
    59221 cgaaaaactg aagaagtcaa tccttgacca cgtactttat ttagcaaata taatttactt
    59281 aaataaattt ttccatttat ctcttcataa gcagtgtaac cgacagtctt ttcttcgctt
    59341 tttaataaaa agtaggacac accttctgtc agttcttttt gaatctgttt ttttgactga
    59401 taagttttca gcatgtaatc cacttgtttt tgaccaatga tcggcacaaa aacttccggc
    59461 catacttctt gtatgactgc catcagctca tccagttcat tttctgttac ttttattttt
    59521 tccatacacc cacgtccttt tttacattat aaatgacctt gcgcttgatg gaataaaaag
    59581 agcatgatca tgctatacac acccaccgac cacggtttca agaaaatcac aatctgcata
    59641 aattccctaa aagataattt cgtcaaacca gctactagac agatcaagtc gtctggcgca
    59701 aagggaagca gcaaggtaac aactagtact tttttaatat ctttcgtttt tcttgtcagc
    59761 aattcatcaa atttctgata cttttttggc gataaaataa gctggacaaa ggctacgcca
    59821 tagtaacgga caagcaaaaa tccgattgct tccccaatca ctaggccaat acaactatat
    59881 aaaagcccaa atccattgcc aaacatcagc atgcccgcta ctgaggagat ccctcccggc
    59941 aaaataggaa tgatcacttg gatcacttgc aacagaacaa atatcatcac tgcatacttg
    60001 ccaaattgct ggataaacgc ttgcaaagac gtgctcgatc gaaaaatccc atgatgataa
    60061 gcataaagaa tcaacacaaa gaaaaaaaac agaccaataa tgggcatgat ctgaagacat
    60121 ttttgtaaaa ctgatccttt tttagacatc tatattcccc acatcttttt tcatttatta
    60181 aaactgcctc ct
//
LOCUS       DACGDM010000009        55693 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.009, whole genome shotgun sequence.
ACCESSION   DACGDM010000009 DACGDM010000000
VERSION     DACGDM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.009"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            281..601
                     /locus_tag="IXR05_000618"
     CDS             281..601
                     /locus_tag="IXR05_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAQ4259163.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            755..1660
                     /locus_tag="IXR05_000619"
     CDS             755..1660
                     /locus_tag="IXR05_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4259164.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1657..2430
                     /locus_tag="IXR05_000620"
     CDS             1657..2430
                     /locus_tag="IXR05_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4259165.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2611..4035)
                     /locus_tag="IXR05_000621"
     CDS             complement(2611..4035)
                     /locus_tag="IXR05_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4259166.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4246..4692
                     /gene="nrdI"
                     /locus_tag="IXR05_000622"
     CDS             4246..4692
                     /gene="nrdI"
                     /locus_tag="IXR05_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4259167.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4757..6739)
                     /locus_tag="IXR05_000623"
     CDS             complement(4757..6739)
                     /locus_tag="IXR05_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4259168.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6753..7649)
                     /gene="murQ"
                     /locus_tag="IXR05_000624"
     CDS             complement(6753..7649)
                     /gene="murQ"
                     /locus_tag="IXR05_000624"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4259169.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7652..8713)
                     /locus_tag="IXR05_000625"
     CDS             complement(7652..8713)
                     /locus_tag="IXR05_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4259170.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8924..9451)
                     /locus_tag="IXR05_000626"
     CDS             complement(8924..9451)
                     /locus_tag="IXR05_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4259171.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(9518..11020)
                     /locus_tag="IXR05_000627"
     CDS             complement(9518..11020)
                     /locus_tag="IXR05_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAQ4259172.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11278..12399)
                     /locus_tag="IXR05_000628"
     CDS             complement(11278..12399)
                     /locus_tag="IXR05_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4259173.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12525..13466
                     /locus_tag="IXR05_000629"
     CDS             12525..13466
                     /locus_tag="IXR05_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4259174.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13616..14512)
                     /locus_tag="IXR05_000630"
     CDS             complement(13616..14512)
                     /locus_tag="IXR05_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4259175.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14781..16121
                     /locus_tag="IXR05_000631"
     CDS             14781..16121
                     /locus_tag="IXR05_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4259176.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16339..16782
                     /locus_tag="IXR05_000632"
     CDS             16339..16782
                     /locus_tag="IXR05_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAQ4259177.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17286..18704)
                     /gene="nhaC"
                     /locus_tag="IXR05_000633"
     CDS             complement(17286..18704)
                     /gene="nhaC"
                     /locus_tag="IXR05_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4259178.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(19107..20330)
                     /locus_tag="IXR05_000634"
     CDS             complement(19107..20330)
                     /locus_tag="IXR05_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAQ4259179.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20361..21200)
                     /locus_tag="IXR05_000635"
     CDS             complement(20361..21200)
                     /locus_tag="IXR05_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAQ4259180.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(21217..21897)
                     /locus_tag="IXR05_000636"
     CDS             complement(21217..21897)
                     /locus_tag="IXR05_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259181.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21899..22972)
                     /locus_tag="IXR05_000637"
     CDS             complement(21899..22972)
                     /locus_tag="IXR05_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4259182.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(23619..24290)
                     /locus_tag="IXR05_000638"
     CDS             complement(23619..24290)
                     /locus_tag="IXR05_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4259183.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(24377..27055)
                     /gene="mgtA"
                     /locus_tag="IXR05_000639"
     CDS             complement(24377..27055)
                     /gene="mgtA"
                     /locus_tag="IXR05_000639"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAQ4259184.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            27714..28151
                     /gene="ndk"
                     /locus_tag="IXR05_000640"
     CDS             27714..28151
                     /gene="ndk"
                     /locus_tag="IXR05_000640"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAQ4259185.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(28173..29039)
                     /locus_tag="IXR05_000641"
     CDS             complement(28173..29039)
                     /locus_tag="IXR05_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4259186.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(29199..31292)
                     /locus_tag="IXR05_000642"
     CDS             complement(29199..31292)
                     /locus_tag="IXR05_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4259187.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(32041..32664)
                     /locus_tag="IXR05_000643"
     CDS             complement(32041..32664)
                     /locus_tag="IXR05_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259188.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32823..34220)
                     /locus_tag="IXR05_000644"
     CDS             complement(32823..34220)
                     /locus_tag="IXR05_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4259189.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(34252..35223)
                     /locus_tag="IXR05_000645"
     CDS             complement(34252..35223)
                     /locus_tag="IXR05_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4259190.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35597..36022
                     /locus_tag="IXR05_000646"
     CDS             35597..36022
                     /locus_tag="IXR05_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259191.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(36510..37211)
                     /locus_tag="IXR05_000647"
     CDS             complement(36510..37211)
                     /locus_tag="IXR05_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4259192.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(37227..37667)
                     /locus_tag="IXR05_000648"
     CDS             complement(37227..37667)
                     /locus_tag="IXR05_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAQ4259193.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37667..38242)
                     /locus_tag="IXR05_000649"
     CDS             complement(37667..38242)
                     /locus_tag="IXR05_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAQ4259194.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(39090..39569)
                     /locus_tag="IXR05_000650"
                     /pseudo
     CDS             complement(39090..39569)
                     /locus_tag="IXR05_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(39728..40429)
                     /locus_tag="IXR05_000651"
     CDS             complement(39728..40429)
                     /locus_tag="IXR05_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4259195.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(40537..41946)
                     /locus_tag="IXR05_000652"
     CDS             complement(40537..41946)
                     /locus_tag="IXR05_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAQ4259196.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(41994..43859)
                     /locus_tag="IXR05_000653"
     CDS             complement(41994..43859)
                     /locus_tag="IXR05_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4259197.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGKPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(43980..44831)
                     /locus_tag="IXR05_000654"
     CDS             complement(43980..44831)
                     /locus_tag="IXR05_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4259198.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(45141..45854)
                     /locus_tag="IXR05_000655"
     CDS             complement(45141..45854)
                     /locus_tag="IXR05_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAQ4259199.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(45922..46248)
                     /locus_tag="IXR05_000656"
     CDS             complement(45922..46248)
                     /locus_tag="IXR05_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4259200.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(46371..46598)
                     /locus_tag="IXR05_000657"
     CDS             complement(46371..46598)
                     /locus_tag="IXR05_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4259201.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(46920..48173)
                     /locus_tag="IXR05_000658"
     CDS             complement(46920..48173)
                     /locus_tag="IXR05_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4259202.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            48234..48974
                     /locus_tag="IXR05_000659"
     CDS             48234..48974
                     /locus_tag="IXR05_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4259203.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(49060..49818)
                     /locus_tag="IXR05_000660"
     CDS             complement(49060..49818)
                     /locus_tag="IXR05_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4259204.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(49815..50843)
                     /locus_tag="IXR05_000661"
                     /pseudo
     CDS             complement(49815..50843)
                     /locus_tag="IXR05_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(50863..54030)
                     /locus_tag="IXR05_000662"
     CDS             complement(50863..54030)
                     /locus_tag="IXR05_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259205.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(54254..55138)
                     /locus_tag="IXR05_000663"
     CDS             complement(54254..55138)
                     /locus_tag="IXR05_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4259206.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(55233..55670)
                     /locus_tag="IXR05_000664"
     CDS             complement(55233..55670)
                     /locus_tag="IXR05_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259207.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
BASE COUNT        15998 a        11731 c         9594 g        18370 t
ORIGIN      
        1 tagttactgt tttttttaaa tgattaataa ataacaactt ctttctatga aattgcaaag
       61 cattcatctt cttttccgct aacgatatat ccgtcagtgc ttggtacact ttactaaaaa
      121 gtatgagatt gccgatatct ggataggtgt gctatactac agaaaaagat atacaatctg
      181 ccaccgggta ggataaagag gatgatcatt ccattaggtc tttgaaggga tgattttcct
      241 ctttttgtgt atttttttat agttaaggag gaatgtaagt atggcatgga tggaattaat
      301 catagcagga attttggaag tattctggtc aacgatgatg aaatggagtg atggtttttc
      361 taaaatcaat tattcttttt acacagtgat tggcatgatt gctagttttt actttttgtc
      421 aaaggcaatc aaaagtttgc cgatgagtct ctcttatcct atctggacag ggattggcgc
      481 agttggttcg gtcataattg gtgtggtctt gtttcatgat aagctgaatc tttccacttg
      541 gttctttgtg gggatgctac tcatcagtat cattggcatc aagattacta gcggccacta
      601 gacacttgga ataagtactg atcagaaaaa ataagccttt ttatttaata ttcaattttt
      661 ttatgaaaaa ataagaaata agtccaatga cctagcgact tctccactca tcaggtgtat
      721 gcttgtacta tctatagaaa aggagtgaat atttttgaaa agtctttcgg tccaagaatt
      781 atccaagaac tttggtcaca aacaagccct cagcgatgtc agttttagct tatcccctgg
      841 caaaatcgtt ggattagtag gtcctaatgg cgctggaaaa acaacgatca tgaaagctat
      901 tttaggactg atccattact cagatggaac aatctgtatt ggtgaaaatg agatttctcc
      961 ctctagtcat aaagggttgg aacaagtagg agcattgatc gaatacccgg gtatctatcc
     1021 attcttaaca ggctatgatc atctgaagtt attctctgaa accaacgatg tatctgctat
     1081 cgacactatc gtgaatcagc tcaagatgga aaagtacatt cacaaaaaag cgaaatccta
     1141 ctcgttggga atgaaacaaa aattgggaat tgctcttgcc ttactgaacc atccgtctat
     1201 cgttatttta gatgagccga tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa
     1261 aatcattacc gacttggcta ctcagggcac ctctttcttg atctccagtc acttactcag
     1321 cgagcttgaa aaaatggtcg atgagctgat cctgatcaat caaggaaaga tcatcaaaca
     1381 atgtacaatg gctgaattga accaaacagc gcaagatttc atcgttatct ctacaacaaa
     1441 tgatctagct gctcgaacga tcttgacaga agctggatat actttggaag atcctgataa
     1501 aatcaagctt ttaaaagaaa acgaagaatt attaggaacc gtgatccagc tattgtctgc
     1561 acaaaatatc catgtgacag acgtccagca tctgacgaat gatttggaat cttctctatt
     1621 ggaaattctg gattcagtaa agggggaaga agaaaaatga cattgcttgt aaaacaagaa
     1681 ttatttaaat tgatcaagaa aaagtcaact gctgttttat ctgttctatt agttgttttg
     1741 ctcataggaa cagcacttct agccaaaaaa tacacgacga tcattgatcc agttgaaatg
     1801 actgctcagc tttttagtgc cacatcttgg attgtcttta tcatgattgc agctgcaagc
     1861 acgatcattt cgatggaagc acaatatggt acattgaaaa atctccttta tcgaaagtat
     1921 tctcgaggag aaatattagt aagcaaatgg atcacattag ttatttattc tgtttattta
     1981 taccttttag ctattattgt cactgtgttg atgaaactga ttcttttccc ttcgatttcc
     2041 ttcacggaga aggtttctac tggtcaaaca ctgatccaaa gcttgttcac ttatactttg
     2101 ggtagttata tcggtttatg gctgatttta agtttagtgt tgatgattgc ttgctttatc
     2161 aatagttccg gcgcatccat ctcagcagga atcgtctttt attttgcttc gtcaatcata
     2221 tctggtatcc ttattgcact catccaaaaa tgggagtgga tcaaatggaa tccgatcagt
     2281 atgttgaatc tgcaaaacca aattggaaac gaagagatca tgaagcaatt gactcatctt
     2341 tctactaatc aaatgctatt cggtaattta gcttacatcg ttttgttctt agcattagga
     2401 tatctcgtat ttaagcgaaa aaatgtatga tgactcatca aaaaagaggc tgtgaaagag
     2461 acgttcagcc ttattgccga ttggctgtct cttaaacacc gtttattctg aaaaaggagc
     2521 tgtgacaaca tttgtgtcac agctcctttc ctagtatgtt tttgaataaa cgacaggctc
     2581 acaacctctc tttatacttc ttttatactt ctatacgtga agcatcccag tggcaaataa
     2641 aaccattgca atcactccga ccatcgtcac acctataagt aaaatcttat ctaagtggat
     2701 atgttgtaca ggctcgtttt gctccttacg tgctttgagg taaaaataaa tgcctggcaa
     2761 gaaaagaaca agaacaagca ttacttcatt aaaggctacg actagcatag cccatacttg
     2821 aaaggcactt gctaaaagcc ctactaaaaa ttggacccat tctttccgct gataagaaag
     2881 tttcatttgg tacaatccta agaaaagcca cgtgaagaaa atagctgctg taccaagtgt
     2941 gtaagcaaag ttataagcac tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca
     3001 taacgtcgtc aatacgatag cataagttgg tgccccattt ttgttgagtt ttccccatgc
     3061 tttaggcaaa agtccgtctt cagccatgtt tcccattgtt tcaatcggta agatcgtcca
     3121 tgagagccaa acaccaacta aagaaatgat caaaccgccg ttgatcacga ctgctcccca
     3181 tttaccaacc atcatttcaa acacatagcc catagcaggc tgcgccttga tcgtttgcag
     3241 ctgattcatc gtcattgtcc catatggaag catggaaacc aagacgtaaa taataatcaa
     3301 gccgaatatc cctagaatcg ttgctttccc aacatctgat tgtttttttg ctcgtgaacc
     3361 tacgacagag gctccttcaa taccaacaaa tacccaaagc atcaccatga tgcaactcaa
     3421 tacttgactg gaaaacggga tcggctgtcc attcgcattc aatataatgt cgctagaaaa
     3481 gttatcaatg aattgttgga tcgaaaacgt gctgatagct actacaataa ataaaaataa
     3541 tggcactaat ttacagaatg tgacgatagc attgacgaaa ctagcatttt cgactccccg
     3601 attcactagc catgcatatc cccataaaaa gactgtactc atcacgatcg atgccagatt
     3661 ttgcccacct tcaaatactg ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa
     3721 agctacgttg cctaaccagc atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa
     3781 acggccaaaa ccttcttctg cgtaactaaa gatcccgcct tttaaatctg gacgtttttt
     3841 attgatatta ttgatcgaca aggagagcat caacattgct gttcctacga gtacccaact
     3901 gaaaatagct gggccgccag ccgatccgga gatgtccgtc ataataccaa atacgccacc
     3961 tccaatcgct gaaccaatta ctaaggcagc aagtggaatt aaaccaattc cttttttctg
     4021 ttgctctgta tccatgtaag catcctccaa aataaaaccg cttttatcaa aaagtataac
     4081 aaaccttttt tatttttact taattaataa aaactttaat agaaatataa ttctaccggc
     4141 ttttttctca ttatacaagc aaagcgccta gtccctttcc aaattacacc accaaaaaac
     4201 ttaaaaaaga tgctatacta aaaggaaaga attggaggat gatccatgaa cattttatat
     4261 atatcgattt caggaaatac gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa
     4321 atgcatgcag aagatcctgt caatcctgaa gttactttaa aagaaatcca tgaaaatagt
     4381 gattttacga aagaaacaga accatttttt actttcgttc ctacttattt agacggcgga
     4441 aatggtttag ataacggtga tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa
     4501 catgaagaca atcataaact ttgtcttggt gtagtcggta gcggaaataa aaacttcaat
     4561 aatcagtatt gtctaacagc caaacaatat gcacaaacat ttggctttcc tttcttggca
     4621 gattatgaat tacggggaac accatctgat gtgacacgaa tttatcagat tttagcagaa
     4681 aacaataaat aataaaaaag aagaagctga aaaatagatt tcagtttctt ctttcgtttc
     4741 tattgtttct atcatattaa gctttgacat ccatcacagg tgcttttgct tttgctttac
     4801 ctgttttttc caagacaaag ttttttacac gatccatatt ggttaccaag acgatcatgg
     4861 atgtttcttt gcctgctgct ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag
     4921 gtgtcacttg ctgcccttct gttactttca catcaaatgg cgtaccgcct aagtcaactg
     4981 tgttgattcc catatgaagc aagatttcta aaccatttgg cgttgtgatc ccaatagcgt
     5041 gtttcgttgg gaagacagag ctgactaccc cagtaactgg agaatagata tgtccgtttt
     5101 ctggttctac aaagtagcct tcacccatca tcttttgtgc aaaaactgga tcacttgctt
     5161 tatctaaaga aacaactgtt ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg
     5221 aagtttgagg tactactttt tcaggcactt catttactgt ggctgtttca gtcgctaatt
     5281 cttctttttc taaacggtct ttaggaatac cgaagaagaa tgtagcaacg aagccaccag
     5341 cataagctgc caataatcca aggatgtagc ctaaccattt accgtcagag atcaatggga
     5401 tcaaagcggc tcctgaaggt ccaatagcga tagccccgac atttccgatc attccgatca
     5461 ctgccccgcc gatacctcca ccgatacaag cagtaataaa tgggcgtcct agaggtaatg
     5521 ttactccgta aatcaatggt tcgccgattc ctaggatccc gactggtaaa gctcctttga
     5581 tcatttctgt taattcttta tcttttttgc agcgaatcca taatgccaat gctgcaccca
     5641 cttgtcctgc accagccatc gcaagaattg gaagcaatag cgtacgacca gtttcatcaa
     5701 tcatttgcac atggattgga gtcaaaattt gatgcagtcc gaacataacc atcggcaaga
     5761 ataatgtgcc tagaacgaag ccggcaaatg ctccaccaac gccaagtacc cagttgatcc
     5821 caccgaccat gccatcagaa atgaaacctg ctaaaggcat gatgaagaaa atttcaatca
     5881 gaccgatggc aatcaatgaa agagttggtg taacgatgat atctaccgca tcaggtacta
     5941 ctttatgcag ttttttctca acgattgaca atagccaaac agcgaagatg acacctagga
     6001 tcccaccttg tccagctgca agagcttcac cagtaaataa gtttttcagt ggtgcttccg
     6061 gattcatccc tgtcagcatc acaacggccc cgataactcc accaagagtt ggtgttgcac
     6121 caaaaacttg tgcagcattg atacctgtat agataactag gtagctaaac atcccgtttt
     6181 tcaagatgtt catcacatcg atatattgtt gccatgttgc tgcatcaagt gttccggctg
     6241 tgactaagtt tgctaaaact gcggcaatcc ctgccacgat cccagtaccg acaaatgcag
     6301 gaatcattgg cacaaagata ttagaaatgt cttttaatac cgatttgatt ttagatggtt
     6361 tttgtttcga tttttgtgcc gctttcattt cttgtgcccg ttcgtttaca cggtcttttc
     6421 cagatgctga tgaatttgct gtagctgtac ttacagaaga aagtttttct cctaatttca
     6481 cgcctgccaa atcaaccatt tgctgtgcta ctttgttcac tttcccaggt ccgatgatga
     6541 cttgaagctg ttcatcttct actacaccaa gcactcctgg aatcgctttt aattcagaga
     6601 catttacaag atcatcattg atgatcttca tacgcacacg agtcatgcag tggacaatgc
     6661 tttctacatt gcccatgccg cctgcccctt tataaatttg ttttgccagt tcttccaaag
     6721 tcagttcgtt ttttgccatg gtcttttccc cctcataagg tcccttttac aaatccgttt
     6781 gcttcagcta attttgcttg agcttcctct ttatcactat ttgtcaaaat catgacgata
     6841 gccagcttaa cattttgatc tgcttcttca aagtactttt cagctgtttc gtaatcagct
     6901 tctgtcgctt gcatgatgat tcgttttgag cgttcgatta gtttttcatt tgttggtttg
     6961 acatcgacca tcaagttatt gaatacttta cctataccaa tcatactgat agtagaaatc
     7021 atattcaaga taagtttttg tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat
     7081 tctggacctg catcgacttc gattgggaaa tccgcgtgtt tactgatttc ggcttgttta
     7141 ttgcaagaaa tcgttcctgt gacagcaccg atcgattttg cgtaatctaa tccaccgatc
     7201 acatatggtg tacgaccgct agctgcgata ccaataacta tatcattttt tgtcaaattc
     7261 agcttgatta gatcttcttg ccctagctca taagaatctt cggccccttc gacagctaca
     7321 gtcattgctt cttctccacc agcaattaga cctatgacca tttccggttc tacaccgaat
     7381 gtcggtacgc attcagcagc atctaacaca cctagtcttc cacttgttcc ggctcccata
     7441 taaatcagac gtccaccttt tttaaaggac tcaatcgtgt tagcaatcac tggttcgata
     7501 cttgtcagtt ctttttcaac cgcagcggcc actttctgat cttctttgtt cattagttga
     7561 acggcttgag aaatactcat ctcatctaat ccaaaagttt cttggtttct gcgttccgtt
     7621 gttaggttct ctaaattgat tttgctcatt tttatcttcc ttcttttctt ataaattgat
     7681 agttcatacc agctttgatt tggttgatca atggtagctc ttctttgata actttagcta
     7741 ctacattcac tttttcatcc gctggcaaat catatttggt taattggatc tcacccatat
     7801 agcgcaaata cttttcgtta tctaaagtaa tagacccttt catacgcgta gctgtatttc
     7861 ttgctgggat aggcggaatc tctcgaaaac gtgcatctac gcttcgtatg acatctcttg
     7921 catcgtcttg ccgattcgta tgcttcccta atatatattc gtaaaattct tcatctacag
     7981 gttccgtatg gagcaagact gtctgttctt tttggaaaga agcaaattgc tcctgaacgt
     8041 tttctgacag acctgcatct ccgatgtaaa caatatccgt gttacttgct aatagatcta
     8101 gagcgcctgc aagaggatgg atccctcgat gttcttccaa agttggcaat ccttgatata
     8161 gtgggcctct caactctgta tctcctggta caaaaccttg gacaaggaga ccttgaattt
     8221 tgagccattg attttttttc tgataccatt ctttgtccag ccctgtttcg ggacgtggat
     8281 aataattatg ccaagcttca atctgtgaga aatcagcttc tgcttctttc aattcatcga
     8341 tatctttagg cgtgatcgtg ctagcattca aactgatttt caattgatgt gaccagtcgg
     8401 caatctgctg attggaaata tgataatcca ttcttaaacc tgttacacca attgctttca
     8461 aaggcgttag atcttctaat gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga
     8521 ccatcaattc tagtttattc tttttcgctt cgcttcctag ttcgatcaat cgcttttgat
     8581 atgccgaaac atcatcttct ggtatatgca tggaagtgaa aataccgaca aagccattgg
     8641 atgccatttg gcggatatac tgtttcttct cttctgacaa agaatcgttc ataaatattg
     8701 aaaagccaaa catattatcc ctctttttct gtatccgtct tcatttctat gactagagta
     8761 tatatctaaa gaaacaaaat ttcaatactt ttattaaaat aattaaattt catttctaaa
     8821 ggttgagttt atattatcaa aagaattgtc ataacctaaa aaaggcactg ctaagcaaaa
     8881 gcagtgcctt gaaatatttt atttaaataa cacaaaaaca taattactca taagaaacca
     8941 attctgtatt atctaccatg aatgtaaaga acccctcatt aggcatcgga tgaaaataag
     9001 cattgatcac tcttatcaag gcattatggc aaactaacag atagacattt tcttcgtctt
     9061 cgatgcattc tttcaataaa ggaacgatcc gtgcatacac atctaagact gactccccat
     9121 ttgggaatcg tacagcgaac gctaaacgtg ctttttgaaa gttctcatct ttgcttggca
     9181 gtccatcata atccccaaaa tccatttcta ccaatcgttc atcaacggtc agcggcaagc
     9241 tgagacgatc agcaactgct tgtgctgtat ctcttgctcg ttgaagaggg gaatggatga
     9301 ttttcgtgat tggaacaggc aaatctacta ccttttctgc tagtttctgt gcctgcatct
     9361 gtcctttttc agtcagcggc acatctgccc gtccgcaaac taatccttgt gcgttccaag
     9421 ttgtttctcc gtgtctcgtt acataaagca tgtgattctc tccttcgttg gcaaagttcc
     9481 ccttaaccat accttgttgt tcttgagatt acaagggtta gattctctca agagaaataa
     9541 tctcagtaga tactttatcc aggaaggttt gatcatgttc cactagtaac atggcaggtt
     9601 tcacgttcaa gatcagttgt tctaattgtt cttgattgaa gacatccaaa taattcaatg
     9661 gttcatccca tgtatatagt tcagctggct gtgataaaga tttagccaat tccacttttt
     9721 tccgttggcc catactcatc tgctcgatct tgttatgaaa aacatctctt tccatcccaa
     9781 gctttcggag gttgttcaaa aatgcttggt agtctacttg gtttttctct gcaaattccg
     9841 ccaacgttcc tcgattgtct tcataatttt ggcttgcata actaatgctc agatgttttg
     9901 gctggtattt ttctcctata accttgccgt tgaatgcccc cagaagataa tggataatgg
     9961 atgactttcc tgcaccgtta ggacctgaaa tcgccacccg ctgatgaggc tcgattgtaa
    10021 aatgaattgg ctcgaataac agattttcat accctaattg aagatcttct acgcttaaaa
    10081 gtcgcttatg gtgagacgct tggctattca tcgtcaaaga atcgatatat tcgatatctt
    10141 ttaatagttt ttctttctcg ctgatctggg tctccatccg attcacgatt gctttggatc
    10201 gtttcatcgt ccgtgcagca tcagcaccca ctgctccttt attcactcgt ctagattcag
    10261 tatcgatgaa tccgacttgt ttctttgttt tatctccttc tcgggaacga gaccattcgg
    10321 ctttttcagc tgctgttttc tttagcctac tgacttcttt tttcaatttt tcattttgag
    10381 ccatttcaaa ttcatcacga agttttttct gttcttcata gatagagaaa ttcccttgat
    10441 aaagttccag ttgacttttt tcgattgcta aaacatggtc cactacttca tcgataaatc
    10501 cccggtcatg gctgaccacg atgaagcctt gttttttctt tttcaaataa gccgctactt
    10561 gttttctacc agagatatcc aaatgattcg ttggttcatc gattaacggg aaatgagtgt
    10621 catccacaaa taaaagtgcc agtaggactt ttgtcttctc tccccccgat agtgtgctga
    10681 attctctcca taagatttca ggatctgttt gcatcaattg gagctctctt tcgatttccc
    10741 atatctcaaa atccgtaata tcatttaaca cgtaataggt taaacgttct ttatcttttg
    10801 tctgttgcgg gaaataggca aattcttgct gatggattac ttgcccttga taaggtagtt
    10861 tgttttgtag aatattcagt aaagttgtct ttcctcgacc gtttcgtccg ataagtccta
    10921 gtttccattg tgtgtcaaaa tttagatttg cttgttcaaa taataatgtg ccttggctgt
    10981 cgtagccgaa tgtcagattt tttatttcga ttttagacat tttccatcac ctcgtaaaaa
    11041 aagaccagtc ctattttcag aactggctaa agaggatgca agggttggat acacacaaaa
    11101 agacccatac atcgaaaaaa ccaagccaat cccgaaaatc tgcacactgc ttccttgtct
    11161 ccacaaggta cagtctgaat gcagctttca tcaatcgact taatttttca atgcacggat
    11221 ccctcacttt gtcctatatt tgaaattacg atagcataaa gaaaatgatt ttgtcaacta
    11281 cttcgggagg atggtgaaaa atctgctaag tgtctgtcct aagatttttg ttttttctaa
    11341 tgtttgcctg tgttccattg cttcttctaa acctattgga cccaaatgaa tacttaagac
    11401 aattgggaga aaatcagaaa gtccttctag ctcttggtct ctacttccgc aaatagcgat
    11461 tattggtttt cgatattttt ttgcaagcac tgctacaccg tatggaactt ttccgtggat
    11521 cgtttgctga tcgatccgcc cttctcctgt aatgatgaca tctgcttgtt cgatcttttt
    11581 ttccaatcca gtgatttggc tgactaaatc gaaaccagaa accatcttcg ctcccaacaa
    11641 aaaaagggct ccaccaatac cgcctgctgc tccacttcct ggaatatcat ctaaatccac
    11701 ctcccagaaa tcttttattt gctgagcaat ctttcctgct tgtttatcta agaaagctag
    11761 cgtcgtatct attcctcctt tttgtcttcc aaattgccaa gcagctcctt gttgacctgt
    11821 atatggattg gtaacatctg cagcgataat caattttact ttagaaacaa gaacgtttct
    11881 tcgatcaaaa tgaagttttt tagtagataa taaaggattt ccttctgtgt acccttctaa
    11941 agaagcaccc aaggattgga gtaatcctag accaccatcg ctacacccgc ttcctcctaa
    12001 agtgacaata atttgttcta cttcttgaag cagtgcatct ttaataagtt ctcctaaggc
    12061 ataactggaa gcaagtcgga tagtttgatc cgttggttta tcaagtagat ctaaccccaa
    12121 tgcttgtgca gattcgatga ctgcggtgtt ttttccttgc caagttgtca ataaatagct
    12181 gatttttcgc tgacggaata agagatccat cccatcaatg gtacgccatg ttcccctgag
    12241 cgcgtaatag attgcttctg cagtattttc tccgccatct gcaatcggca cattgatttt
    12301 tcttccttta cgatcttccc agccatttag aactgcctga tttagttcaa atgaagaagc
    12361 acttccttta aatgaatcaa ttgccgccaa aatatccatc tgtatccctc actttcttct
    12421 taagtaagac actttttttc atttttttca aacaaaacaa tgctattttc ttccattttt
    12481 ctatatacta aaagggaact cattgaataa aggagagaaa aaacatgaaa atcgcaatag
    12541 ctggggccgg agcaatgggc agccgaatcg gattgatgct acatcaaagc ggaaatgagg
    12601 tcctcttgat cgatcgttgg cctgctcaca ttgaagccat tcgtacaaat gggttgattg
    12661 ctgactttaa cggtaaagaa gtggtcgcaa aactgccaat ctattcacca gaagaaatca
    12721 tcgaaagcaa cgaacacgtg gacttgatcg tagcattaac aaaagccaat caattagatg
    12781 atatgttttg ttcgatccaa tccattatta ctgacaatac ttatgttttg tgtttactaa
    12841 atggattagg tcatgaagat gtactggaaa aatatgtgcc aaagaaaaat atcttatttg
    12901 ggatcacgat gtggacagct ggtctagctg gtcccggaaa agtcacattg ttaggtgatg
    12961 gagaaatcga actagagaac ttggaaccag aaggcgaagc atttacaaaa aaagttgtag
    13021 aagtctttca agaagcaaat ttaaatccga tctatagcca taacgttcgt tattccattt
    13081 ggcgaaaagc ttgtgtaaat ggaacattga atggtttatg cacgattttg gattgtaata
    13141 ttgctgaact aggcgcgcaa aaagcggcag agagcatggt tcgaacaatc gtatctgaat
    13201 ttgcttctat cgcagcaaaa gaaggaatca tactagatca agaagaagtg taccaacata
    13261 ttgcttctac ttatgatcct gacaacatcg ggttgcatta cccatctatg taccaagacc
    13321 tgatcaaaaa ccatcgtttg actgaaatcg actacatcaa tggtgccatt tggcgaaaag
    13381 gacaaaaata tgatattgct acaccatatt gtgccttttt gacccaatta gtccatgcaa
    13441 aagaaggaat ccttggcgca gaataaaagg ctctctgatg agaatcagct gaatcagcag
    13501 ctggttctct ttttttaagc ccaataaaag atcaaaaaga aaacacaact ctcatgatgc
    13561 cataagaatt gtgcttgttt gtttcagtac ataatctctt caaaatgtag gttttttatt
    13621 tgttttcaac agaggagagg tcatattcgt attgctcata aatagtggaa tcgttagtga
    13681 taaatcgttt tgcccaattt tctgcatcat aaaattccaa tagctctgat aggattggct
    13741 taaatggtgt atgcagaaat tccggtaatt catctaaatc acgttctcga agcaaaaaaa
    13801 tattttcagg acgataaaaa tgataatgag caatcgcttg attatccgtc actagtttct
    13861 tttgaaaata catggattca aatgtccgca aagtcactcc ttgctgaccc tcccgcaaca
    13921 gttccagaat cccgcgcgat tcccctgttt ttttcaggta ctcttcataa gtaagatatc
    13981 caggttgttc attccctcga tgtggaagaa tgaaatagtt ggtcgtaaca tctcttttta
    14041 taaattcctg cttatagctt tctgctcgtt cttttctccc attattcgtt gcaccaaaaa
    14101 atagatccgt ctttggttcg ctagaagaaa aattcatatg tttcgaataa aatgaactat
    14161 tatgtttcag cccaagttct tttgcttcca aaaaatcaaa atgataaatc tcatcgattg
    14221 ccggttcatc ttgtgcctgc ttcagcatcg cctcgtgttc tgctttgaag tgattccaaa
    14281 aaaataacac aatttttgca ttggtaaatg ggcgcacgcg tcgagccatc tccatatcaa
    14341 atccataatc taaaaaaacg atcagctgat aatttgccaa ctgttgtcta gctgatttaa
    14401 tgaattccga ctgtagtaaa tcttttccgg accaaacatc taaagagcgg atggaaggca
    14461 aaaaataaag tgatttattt tttgcaacta gcagtacgtc atttttgttc atcttttccg
    14521 cctcactttc tctgtcactt tttcctatga tagcctgttt aaatagtaaa aagccagtaa
    14581 aacgtttcct atatttgtat gaaaatttaa catttgtatg aaaatatgat gaaataaatc
    14641 attcttctat taaaattcgc ctaaaagttt tctgaatagt tgtaattgtc tgaaaatttg
    14701 ttatcattag tcattgttaa atattgctat ttattcttaa tataaatttt gattgtgaat
    14761 ttaaaagaaa gaggtcattt atggaagata aaaaattgaa aaaacaactt agctccagac
    14821 atatcaccat gttagcttta ggtggagcaa tcggtgcagg tctatttaaa ggaagtggcg
    14881 aagcgattgg gatcgccggc ccttctgtat tgattgcttt tttgattggt gggctgattt
    14941 tatatatcgt gatgaaaggt ctgggaaaaa tcgttttaag cggtggcgac acgcatcacg
    15001 gattatctgg tttgatacgc ccttatctag gtgctcattc tgctgatttt actgattggg
    15061 tctactggtc tatgtggatt atcaatatca tcgctgaagc tgttgcagct gcttcctttt
    15121 tgcagttgtg gttcccgcac attccagcct gggtatttgt ttttatgttg gctgttttaa
    15181 ctacgatcat caatctttat tcggtacggt tattcgcaga aacagaatat tggctggctt
    15241 ttgctaaaat cagtgtcatt atcttactga tcatttttgc tacttatctt gtcggtcagc
    15301 aaatgttggg cacaggcgtt ttccctaccc ttcagcaatt gactgaccat ggtgggttta
    15361 ctcctcatgg tatgaaggga atcatcagtt ctttgcttgt agttatctat tcttacggcg
    15421 gttctgaact gattgctatc acggtaagcg aagcagatga tcctaaacgt gcgattccta
    15481 aagcaatcaa aggtgtcatg ggaagaatca tttcctttta catcattcct ttgtttttgc
    15541 ttttgattct ttttccttgg aatactttag caggcacgaa tgtcagtcct tttgtgatgg
    15601 tatttgaaaa aatgaatatc ccatttgcag cggatatcgt caattttgtg attgtccttg
    15661 ctttgttctc atctatcaat tcgggtgtgt atgcatcttc aagaattttg ttcttccgtt
    15721 tgaaggatcg aaaaggttcc tctagaaaac tagctgtttt aaacaagcat caagtaccgc
    15781 aacgtgctgt tttattttgt accagtgttc tttatcttgg tgtagctctt tcttattttg
    15841 tcggtgacaa attatttggc tatctggcag gttccctttc gtatacagta ttattgatct
    15901 ggatcattat cagtgcggca tcctttgtac tggcactaag aaaaggaaca ttatgggata
    15961 aaggaatcag cttttttgca ttagctgtct taggattgat tttccttggt atcctgttca
    16021 cgaactccat tggggtaact gtattgactg gcctgcttta cctgttcatt tatttcagtt
    16081 atcaaaaaaa gaatgatgcg ttcgtattga cgaatgaatg aaatcgatag aaaattttat
    16141 tttatttatg tggaatagat ggagctattg aagaaaggag ttgtgacaaa agtcttgttg
    16201 caactccttt ttccgaataa acagtctcat gacctcttgg taaacggtgt tcaaaaaccc
    16261 tctgtgcaaa ataattgatt gttctccatg ctcatgacat gatagaagaa aggaatgaaa
    16321 aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt tgttgatgat cggtgtttca
    16381 acggtagtta tgtttggtat gatgtacttg aatgtctatg cgctcgatca tatcttcttc
    16441 agtcgtacac gagtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgctg
    16501 ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg ttatgatctt agccgctagt
    16561 cttcttgttt ttgccggttc cttgtttatg gtacgaagcc aaactactgt caacgacaca
    16621 gcttggatga aggccatgat tcctcatcat tctatcgcta tcctggcaag taaacgagct
    16681 gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa
    16741 gagatcgaca aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc cgtccaaata
    16801 aaaaaagagg atgttccaga agttatcagc ttcaagaaat aagaagaagc tacttctgga
    16861 acgccgtgaa taaggggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa
    16921 caaaaatagc ttctcctatt tttcgtttgg ttaggcttat taccgcagat gcaagctttt
    16981 gaacaccgtt tattaagagg ttgtaaaatc agcgttctga cctgagtatt agagagacaa
    17041 atggaaaaat agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat
    17101 tgaacaccgt ttatcgagag gttgtgaaaa agtcgcttag tttcgcgtat taagaaaaat
    17161 tttgtgaaat ggctttccac atttttgtat aaatttggct taataccgag aaactggctt
    17221 ttgaataccg tttattcgta aaagggattg tgacaaaagt cttgtcacaa tcccttttta
    17281 tgtttttatt gttctaattg cgctgtcttg cttactgctt cttgcggttt cacaaatttt
    17341 tttgagattc cccaacctgt gaaggcactg accatcgaaa acacaggaga aagcaaactg
    17401 aaaaatacga atggcaagta agtgagtgta ggaataccaa atgtacttgc tacgaaactt
    17461 ccggcaattc cccaaggcac taagtagttg attactgttc caccatcttc tagcgttcta
    17521 cctaatacag ttggatcaaa tcctgctttt tcataagttt ctttaaatgc attaccaggc
    17581 agaataacag ataggaattg ttcaccaata aaaatattta ctccgatact tgtcatcaat
    17641 gttgtaaaaa tcaaatttgg tgtgttcgtc atctttcttg atactcgttc catcacggtt
    17701 gagatcaagc caaattcgat caacaatcca cctaatgaca aagttagaat aatcaatgac
    17761 acagtaggca tcatactttc gattcctccg cggctaagca gtgaatcgat ttgttggttt
    17821 ccagtatttg aaacaaaccc tgattcgatg accccagcca acttcgttaa ggaagtttgt
    17881 gggttttgaa taaaaatcat tcctactgct acagcgatat tcaacaaaat cgttaaaatt
    17941 gccggcacct ttttccatgc acacagtaac attaaaaata aaggaatcag tgaccagatt
    18001 gaaatagtaa agtttgcttc tagaacatca gtcacttcac gaatagatga aagacttgcg
    18061 gctttacttg tgtgtcctaa aatcatgaat aaaaagaaag aaacaacaaa tgccgggaca
    18121 gttgaccaca tcatatgctt gatgtgtttg aacaaatcgg catcaacaat agctgctgct
    18181 agatttgttg attcggataa tggagacatc ttatctccaa aaacggcacc tgaaacaata
    18241 gctccaacaa ccagcgctgg atttaagcct agtgttgtcc caataccgaa aaatgcaatc
    18301 ccaatcgttg acataacagt aaaggcactc cctacagcgc tacctacgat tgcacacaca
    18361 acaaatacag aagggacaaa ccactggaca ctgatcaatt tgaacccaat gaccattaga
    18421 gttggaatga tccctgcttg tatccataca gcaatcaatg aaccgactaa aataaaaata
    18481 aagattggga tgattcctgg tttgatgcca ttgatgattc cttcgtgcag ccaatctgtc
    18541 gggtatcttt ttatcactgc atacaacatg accattccga tcgctgctaa gatcgtgata
    18601 ttaggtgaga cctttaatcc gacaacgcca atcgcaatgc ctaaaacaat aaccattaat
    18661 acaagtgttg cttctaaaaa acttggtgtt cctttttttc ccatgataat ctctcctttt
    18721 ttagttgttc ttatgttcta aaaaagttaa gatatcggat tactccgccg caattcatcc
    18781 gcgattcctc ctttataaaa ataaaaagac ctgttttaaa ctaaggacga atgactccgc
    18841 ggtaccacct taattaaaaa cagatctgtt tttcactttc aaacttttat tcaaatgtat
    18901 ggactttcca tgtaattcgt caattaggct tgatcggttc acagcgacca ccgactttct
    18961 gaacaaaaca cctaaccgct actgcgtgaa aagttgactt gtacgaagtt taccttccat
    19021 aagatcattt gtcaatgaaa aagaaaatat tttttcattt ttctgaaaat tatttttata
    19081 actttcacac acaagtttat tttttactag aaagtagcgc cctcttgttt ttttcttgct
    19141 actatttctt gatgttcttg cttgattctt tctaatagct ttggctcttt caacagatca
    19201 agagctgtat tggcgagtag ttctgctgca atcgcaatag aagcaaggcc tttgtcactt
    19261 ttagcagcag ctttgaattc ttctgtgtgt ccggcaatat atgtctcaga gattgctacc
    19321 gtaggctgga ttgttggtat gacttggctg acatttccta catcagaaga accgagactt
    19381 gttctttgtt ccgtttctat ttcttcatct ggaacacctg cttcttttgc atgctggaag
    19441 aataagtcat caaaagaagg agtaacgatg acatcatcaa ctgcattttg gaacaatcca
    19501 aactcaaaag tcgtgcccgt acttatcgca gcacctcgta cgatattttc cactttttca
    19561 tatactttat ctaatgtttg ccgatttcct gcacgtaaat agaaacgtcc agcagcgtaa
    19621 tctggaatga cgttggcagc tactcctccg tctgtaatga tcccatggat attgacatct
    19681 tttggcaatt gcaagcgtag agcgttgatt ccattaaaca cttggatcaa tgcttccaaa
    19741 gcatttactc ctttttcagg tgctgctgct gcatgggaag cgacaccgta aaatttgatg
    19801 tcgactggat cattcgctaa agattctgtc gttttcccat aacgaaaagc tggatggacg
    19861 cataacgcta catcgacatc ctcaaaaaaa ccttctcgaa caaagctgcc tttagctgat
    19921 ccgttctcgc ccccttcttc ccctggggtg ccatatacac ggatttctcc accagtttca
    19981 tcaatgaatt gcttcactat gctggcggct aatacggagt aagtaccaaa caaattatgc
    20041 ccgcatgcat gaccaatacc tggtaaagca tcgaattctg ccaaaaaggc aattgtggga
    20101 ccgggtttat tggaaatata acgtgcatca aaggctgttc ggtgtccagc tacttctttt
    20161 tctacccaaa acctttcttt ttctaattgt ttaatcaacg ctgctgagga ataaaactca
    20221 tagttactta cttcaggatg ttcgtggata tctagagcaa gtgcttgata ttctggtaaa
    20281 cgatattgga ttagatcctt caattggttt gttgagattg ttgttgtcat aaaaaattcc
    20341 tcctatgcta gtcatttttc ttattttctc ccgaatgttt cccatgcagg cacgcttgat
    20401 ccttttgatg ttttctcgat tactttgact gtgtcttctg tttgataagc gtctactatt
    20461 ttttgatacg ttttattgtt ttcatcttct tttcttgcaa cgatgatatt cacataagga
    20521 cgtgcatggt catccactgg ttctaagaag atggcatcag aagcaggatt aaatccagca
    20581 tctacagcta caccgctatt gatcactgaa atgtctacat ctgacaaagc acgtgctgtt
    20641 tgggaagcat ctaattcaga aatgtctaga ttttttctat tctcggtaat atcagaaaca
    20701 gtgggcgctt gtccttttgc cttatccact ttgatcaatc cagcagtttg caataacaga
    20761 agagctctgc cgccatttgt aacatcatta gggattgcta cttttgctcc gtctttgata
    20821 tcagctacat ccttcaaagt gttagaataa attcccagcg gtgcattgac agtatttccg
    20881 atcgatacta aatcagttcc gtgttcttta ttgtaattgt ctaaaaagaa ttgatgttgg
    20941 aaagaattca aatcaatcga tccatctgct aaagccacat ttggttgatt gtaatctgta
    21001 aatttcacgt attccaaatt aatgttctcc tttttcaaac ggtctttcac gttgtcccat
    21061 acatctgtat cttctccaat aatccctagt tttacgatag tttctttttt gtcagttgta
    21121 tctgcttttc cttggctaca ccctgccaac caaataattg ctacaaatgt aatgactaca
    21181 aaacgaataa tttttttcat tttttctcct ccactttcaa tgtgtaattt ttttaatcag
    21241 ttgattactg ataaattgac ttaaaaaaac taagattaga atcaataatg tagccacaat
    21301 cgttacatct gtttggaatc gattataccc tctcgatata gcaagattcc ctaatccgcc
    21361 tgcacctact gctccagcca tggtagtcag tccgatcacg ttgatgatag tcaacgccga
    21421 gacccgaatg ataccaggca aaccttctaa caaatacaca cgtaaaatga taccgattgg
    21481 actggttccc atcgcttctg ccgcttcgat caccccagga tcaacttcta gcagtgcgtt
    21541 ctcgatttga cgagcaaaaa acggaacaac tccaaaaatc aatggcacta aagctgcttt
    21601 cgcaccaatc gtcgttccaa ctaagaaacg agtagtcaat gctaaaagag aaagcaagat
    21661 aatgaaaggg atggaacgaa tgatattgat cagcttatca agtatttcaa atagcagacg
    21721 gttagctagt aatccattag ggcgtgtcac tactaacgtc acacctaaga tgattccaat
    21781 catcccgcca atgaatgctg tccaaaaaga catatatagt gtttgcttcg tcgcttcgac
    21841 aaattcatcc ggaatcaaat aaacattggg caaatatgtt ttaaagaaat cagtcatttt
    21901 atcttcctcc ttcgatcact ttgatacgac tatctaaatc gtttttttgt aaaatattta
    21961 tttttacacc agatttgatc aaataatcca atgctttttt ccgctgtttg gtttctccag
    22021 ctaaagtaac gatcaaactc cctaacggcg tttcttgtaa taactctaca ttgccatata
    22081 aaatattcgc tgttacttga tatttgctgt acagatgagc gattagaggt tcgttcgtct
    22141 gatttccaat ataacttaat tccaccagcc atttattggc gatctgatcg gcaaaagcag
    22201 aatgggcaat gatcgtttct aatgcttggt caagatgagt agctgttcga ataaaatctt
    22261 tggtcaattc ttcttcagga ttgctgaaga tctggatgct gctacctttt tcaacgattc
    22321 ttccatcttc cataaccgct accttgttgc agatttcttt gacaacttgc atctcatgag
    22381 tgatcaggac gattgttaaa cctaactggc gattcaattt ttttaacaat gcaaggatct
    22441 gaagggtcgt tttcggatca agtgcactgg ttgcttcatc acataataat accttaggtt
    22501 cattcgccaa agctcgtgcg attgctactc gttgtttttg tccccccgac agttgtttag
    22561 gataagcaga tgctttttct tccaaaccga caagttccag tagttcattc actttttgac
    22621 gacgttcctg tttcgatttt ccagaatact ttaaagaaaa atcaacgttg tcaaaaatag
    22681 ttcggctttc cattagattg aaatgctgaa agatcatacc gatggccttt ctttcttttc
    22741 gcaattcttt gggagagagc tgactcagat tcgtctgatt gacaatgact tctcctgctg
    22801 ttggtttctg cagcaaattc atcacacgaa ctaacgtact tttccctgca cctgagtaac
    22861 cgacgattcc ataaacatcg cctttttcaa tcgttaaatc tacagaatct actgcctgta
    22921 tctctttttc tttttgtttg aaacatacag aaacatctcg caattcaatc attaaaattc
    22981 ctccttatct aaaaaaagcg tcctcaagaa aatgaaaatg tcattttctt gaggacgctt
    23041 ttttgcgtgt taccacctca tgttcaagct gtgttcacac acaactcctc ttcaagtacg
    23101 atcatactct agcaagatat cggtcgcagc cgtcatcgcc ttacatctat gctcgggatg
    23161 aattgctcga tggccatttt ccaatagtcg ttccttgctt cttctcagct accgaagctc
    23221 tctgtcaaag gttcttctat cgtacttacc atttcaatgc aaataatatt caaaaaaaaa
    23281 gtccttttac taacataaac tatgtcagta aaaggacgac gtatcgcggt accacctttt
    23341 ttcggaagtt tccttccctc aagcccaaca tctcaaaaag agagattggc gttcgtttta
    23401 acggtcgaac agttccgaat ttgcctactt atcgacaaat tattctccaa ggccattttc
    23461 agcttttctt acttgactct tctcaccagc cagagcctct ctgcaaagtt tccaaactta
    23521 ctttcctttt caacgaaatc gatattttgt tgttgggatt aatctacatg aggaaaactg
    23581 aaaagtcaag tacgaaattc aaattatttt ttctatattt atttttctgt ttttttattt
    23641 aacatttcaa taacagttcg aagatctttt ccttccgcaa gaagtttcaa tttttccttt
    23701 tcttcgacgg tataatttcg gacaaaactg gaatcaggta tcaaaacaac gcctaatcct
    23761 gctcgtgaag cagctgttgc tcctactaaa gaatcttcca ctgcaaaggc tgaactagct
    23821 tctaatcctg ttcgttccaa agctgtcaga taaggaatcg gtgaaggctt gttctccgac
    23881 acttcgtctc cgaatgtaaa cgtgtccaag taatcagcta atttaaagtg atccaagata
    23941 tctgttgctc ttttcgtaac agtggtcgta gcaatgccta gtttcatatg acgttctttt
    24001 aagtctgcca atatttcttt tgcatatggt tttaagtgga tggctccgct tgtcagctgt
    24061 tgataaaaat attcttcacg cttcgctcgg acttcctgta ctttttcagg gctacctgct
    24121 gctttcacta aaatatcaaa actttgtttc cagttttttc cgccccaagc gtcaacgatt
    24181 tcttttggga tatggatatc aaattgctga aatccccaaa gccagccatc acgatacgtt
    24241 ttttctgtgt caactaacaa accatctaaa tcaaatattg cacctttcat ctatacatta
    24301 atcctttcca aaacaataca catagtttag cacgactggt ccaaaaagaa cagaagcaaa
    24361 gaaccagcct tctcgtttat aagagttctt ggaatcgacg gatatagatt ttcttcacag
    24421 ctgtcacaag cgccagataa gcgatgactg tagcaaataa ccataaccag taattgccag
    24481 gaagtggcat caagcctaat tcagcaccaa aacttgtaaa aggaaggaca gaaccgacaa
    24541 taattcctaa tgtagtgata acaaacatgg caaatgttgc gttgctttgg ataaatggta
    24601 ctttcggtgt acgcagtgca tggagcacta aggtttgtgt ccatagtgat tcgacaaacc
    24661 atcctgcatg gaataatgcg atgaaaatca ctcgctgtga actatccaat gtatggaaac
    24721 ttccgcccac tacagcagga caaataacaa aatacatcaa caagtaagta gtaatatcaa
    24781 atatcgaact tgttggacca aagtaaacca tgaattcccc aatactagat gcattccatt
    24841 tttttggctc gtccaaatat tctttatcca tccgatccca tggcaaggaa atgcaggaaa
    24901 catcatagat cagattcaaa aacaaaagtt gtaaaggcag cattggtaaa aatggcagga
    24961 acgtacttgc aatcagcacg gaaaacatat tgccaaaatt agaacttgct gtagccttga
    25021 tatatttcat gatattccca aaagtttctc gtccagaaag aaggcctctt tccaaaatcg
    25081 tcaaatcttt ttctaaaagg atcacgtctg cagattcttt cgcaatatcc acagctgtat
    25141 ctacagaaat accgatatca gccactttca ttgcaggagc gtcattgata ccatctccta
    25201 aaaatccgac agtatgacca tttttacgta aagctgtcgt caaacgtgct ttttgctgag
    25261 gattcaattt tacgaatact tcatggtctt cagctacttg tgctaattca tgatcactca
    25321 tttccgagat tttctcaccg gtaaccaatt cattgatctc tagacctact tgacggcaca
    25381 ctgaacgtgt aactaattcg ttgtccccag tcagaacttt tacagctaca ccatgttctt
    25441 tcagagcttt caacgcttgt ttcgttgttt cttttggtgg atcaaggaaa gcaagataac
    25501 caatcaaaac catgtctgac tcatctttga ctgaaaattc tccaacgacg cttggattgg
    25561 tcttttgtgc gacaccaatc actcgtaagc catcttcatt aagtgactgt acttttgcaa
    25621 gtacggcttc ttttcgttct tttgttaatg gtgtaacagt accgccaaga tcaataaatt
    25681 tagaaatgtt cagcatttct tcaatcgcgc cttttgtgat catttgtgtt ttaccagctg
    25741 gatcagcaac cacaacactc atacgacgac gttcaaaatc aaaaggaatt tcatccactt
    25801 tttgataatt gatcttatct gtatctaaag tttctgttgc ttcatcaatg atagccacat
    25861 ctaacaaatt tttcagccct gtttgatagt agctatttag atacgcatgg cgcaaaacac
    25921 gatcatcttc atttccttca caatccatat gatattcaag aatgatttta tcttgtgtca
    25981 atgtccccgt tttatccgta cataacacat cgattgcacc aaagttctgg atggcattca
    26041 aatttttgat cactgttcct tttttggcca tcacacttgc tcctttgacc aaattcgtcg
    26101 taacgatcat tggaagcatt tcaggtgtta gaccaactgc tacagatagt ccaaaaagaa
    26161 aagcttctag ccaatcccct tttgtaagcc cattgatgac gataactgct ggagccatca
    26221 atgacataaa tttgatcagt agcatggatg ttttatggat gcctaattca aagcttgatt
    26281 gaattggttt ttcagatagc gtttctgcta catgaccaaa tagtgtttca tttccaacag
    26341 aaacaatgat tccttccgca cttccactga tgacattact tcccataaag acaagatttt
    26401 cgtaacttgt ttcgctttgc tgatcgtctt cacatacttt cgcatgcttt tctactggat
    26461 agctttcccc tgtcaatgct gcttgggaaa tgaataaatc ctttgcggac aataaacgca
    26521 tatccgctgg tatcatatcc cctgctgaaa gccgaacaag atctccacag acgatttctt
    26581 ccataggaat ctctgtgtac tttccattac gttttacagc tgccgttact ttcacaagtg
    26641 atttcagttt ttcagccgct tgattggaac gtacggactg aatcaacgtc attgtcccgc
    26701 tgacgataac catagtgaag ataatggcta caccgaaaag atctttatct ccaggagctg
    26761 ctaatacata ttccgtgatg aatgaaataa ttcctaatgc gatcaacact aatgtaaatg
    26821 gcgtgatgta tgctttcaat atttctacaa tgaatggtgt ttttttgcca tatgaaatcg
    26881 cattttcacc gtaattttct cttgaacgtt cgatttgttc ttctgtcaat ccatttgctg
    26941 atgcatggaa tagttcaaat aattcttgtt tcgtttttcc agcaaaagct gcatagattt
    27001 tttgtgtatc tttctttttt tccatctcaa tctctccttt gtgtccaaaa gacagctgtt
    27061 ctcgctgctt ttggtcttta gctattcatc ggatcgatag agaaaaaact gaaaggggct
    27121 gagaacagat agataatagc cctggccttt cctctagatc cttgtttttc gaatgactgt
    27181 catccatttg ttctcatctc ctttactaag taattttaat tcatgacttc caatcatttt
    27241 tcgaatagtt atttttccaa ttagaccacc tcctttttat ttttcaccga tggggatttg
    27301 cggcaacaaa aaaacctctc gccaaatact cagcgaaagg tttgaaaaag catattaaaa
    27361 aaagcttctc agatctcatc gttgagtttt gacactgtac aacgtaaaaa gcagatacct
    27421 gcttttagct accttatgaa aagccttatc tcgacaattc ctgttctacc cattggcgtc
    27481 tctcgacgtt tttgggcagt agcctatgtt tgtataggag cctcacctaa caaatcttat
    27541 tcggttttcc ttcgttaata taacaactaa aaaagaggat gtcaaatcaa ttttccatgt
    27601 ttttcatact ttttttaaaa tacacacgtt atattcctgt ctcacgcggt tttatttgtc
    27661 tcattttcca cctcccgcta taatagaaat atagtaggaa acgaggtgct gttatggaaa
    27721 gaacacttgt tattatcaag ccagacggcg tgagacgcca tttagtcgga agcatcatcc
    27781 aacgttttga agcaaaggga ctggccattg ctgaaatgaa gtttgaaact atgactcctg
    27841 aattagcaaa agaacattat cagcacttga ctgagcgcag tttttttgat gaactgatcg
    27901 attacatgac ttccggtcct gtcgtttatc ttgtgctggt cggcgaggaa gtgatcgata
    27961 tcgtccgtaa gatggttgga gcaacaaaag ctgccgatgc tgttccaggt acgatccgag
    28021 gagactacgc gctgccgggg actgaaaaca tcattcacgc ttctgattcc cgtgatgctg
    28081 cggtaaaaga gatcgcccgc tttttcccgc cattcgatat aaacaaaccg tctgaaaaag
    28141 cggcgaagtg atacaaattc taaactgctg gtctagttgc tgggttcagc aatggccagc
    28201 agttttttct ctaaggacct ccgttgattc tttcctaaca tatattcgag cactgtgaag
    28261 aattcttggt agtctttcgt cttttcttcc cctaaagcag cagaaatcaa tctttgataa
    28321 taatctgcca tcaatgtttc atagatcact gtacttcttt ctttatgtgc taagctccgt
    28381 ttcatatctt cattcacact acgtgccttt ttcaaccgac cattttctat ataaaacgaa
    28441 gtcaggttca ttaaaaaagt aaagagatac tgctcatgat tgttcaactg tgctaatcgt
    28501 cgcattcttt ttttgatttt caaataattg ttctcaatga accgatcact gaatatccaa
    28561 ggaaaatcag ctagaataga tagttcaaat tgaccatagt ctggtatctg catcaagtat
    28621 tcttcaatga ttcggcattc ataacgtaaa aattcaaatt ctgtctcaga tacttctgtt
    28681 ttttcgacca tgtgaagatt caaaaccaaa taatacagat cttctgtttt cttaaaatgc
    28741 ctacggttat tgctgatctc tttataagga tcaaagctgt cttcttgtac ccgatctagc
    28801 attcgtcttt ttttctttaa ctttattggt tcatccagct ggtttcgcat ccattcatat
    28861 tctgcaagtg tcatgttcat tcgctctaaa aatgatctca atgttacaaa tgacattttt
    28921 ttcactgaat ttgtctcaat cccgactaga gaagtcttaa aacagattcc ttccgctaat
    28981 tgggactgtg tcaacttctt gttgactcga agtttcttga tcaattcacc atcatacata
    29041 atagttctcc tttttaattt aaatttttcc acattcaata aatagatacg ttaaaaagga
    29101 aaaatacacg aaaaaaataa aaaaatgttt ttttcataaa aaataccaac cttcaagcat
    29161 tagaatgttg tctaactact gaaggttggt ttgattgttt attgattatt tttttgctgt
    29221 tcaacgtctg ttcttgttac tggatataag ttggttgttg ttttattacc attttttgaa
    29281 aagacacttg tcgaatgttc gcctttttgc ttttcgattg cttcattacg ttccgcttca
    29341 tttttatagt catatttttt cggatcaatc gtctcaaatc cgtttggcac ataaaaccgc
    29401 aagagatttt cctgattcag cttatctgaa agacttaacg cagtcttgac tttttcctga
    29461 tctttggaga tttcctcatc gattcctgct gctttcgtat cgatgatttc tcctgtctga
    29521 ttattgtaag cttttcctcc taggacggtg tatttgggtg tcacaaagtt cccatttcga
    29581 aaagcaacta cttgatcatg ctgagaagat aataagtctg taccaaaatg aagataatct
    29641 ttatcatcga ttcccaatag atgtagtaat gtcggcaaaa catcgatttc tccaccgtat
    29701 tcatgattga ctgtcccttt agtataacca ggcatatgga tcatcaatgg cactcgttgc
    29761 atctgtgcgt tgtcaaattc atcccatgta tctggatctt taccaagagc gcttgctaaa
    29821 tctttattat ctgtattcga gatcccaaaa tgatccccgt aaatcacaaa gattgaattt
    29881 tggtaaatac cagatttttt caaatacgta aaaaattgtt ccaatgattg atccagataa
    29941 tgtgccgttc gaacataatt atctactgtg ctattgccag tattcaaaga tggaaagtcg
    30001 aaattcttgt catccgtata ataaggcgtg tggttggtta cggaaagaaa tttcgtgtaa
    30061 aacggctgtt gtagatgctc aagatattgg gcagattctc tgaataaatc tttatctaat
    30121 atcccataac ctaacgtttc gtcggattca tcaaaataag atcgatcaaa gaaattgtca
    30181 taacctaagt ttttatatac atgatctcta ttccaaaaac tagctacatt cccatggaaa
    30241 acagcgcttg tatagccttg cttttgtcca aggatcgctg gtgcggcttg aaagacattg
    30301 tctgacccaa gttctgtgaa taatgagcct tgaggtaaac caaatgtgcc agtttccaac
    30361 atattttcag catcacttgt ctttccctgt cctacttcat gaaagaaatt gtcaaagctg
    30421 atcgttgctt gattctggaa aatactattt aaaaacggtg tgacttcttg tccgtctacc
    30481 ttcatattaa tcaaaaactg ctggaaactt tctaaatgga gaacgatcac atttttccct
    30541 ttagcgatcc caaatgtttc gggatttggc tctgcataat gtttctttgt ataatctaaa
    30601 acttcatcaa tcccattact gcttgcatgc gcgcgaacac tgctagtcat tcctgttttg
    30661 attccgtcat aaatagtata cgcatcgatt cctagatatt tgacaatata tgaacggtca
    30721 aatgttcgct gcagcaattg tggacggttg gcttcgctca gcgctagatt tcctgaaaaa
    30781 ataagccctg aaagacaggt aacagcgata gccatcggtt tgccgacagg gttgcttttg
    30841 ataggtattt tcttgacctt caaccaaacc agtagcccaa tgaacacagc gatatccagc
    30901 cagtagatga catcatgggg cttcatcaaa gaaaaggagc ttcctgacaa tccttgcgac
    30961 actttcgaaa agcctaatac agatttgact gtaatgaaat ctgtgaattc ccgataaaaa
    31021 ataatattca agtacaacaa aagcgtattt aaaatatcaa tgatcaaaag aatagctaac
    31081 gctggctttg gctttttaat atacaaagaa aggccaaaaa acaataaggt agtcgcaatt
    31141 gggttgatcc acaagataaa gtactggatc gtaccttcca cacctaatga aaaatctgca
    31201 tagtaggcaa tgatcgtctt cagccagaaa aagaaaacag ctgtcaaaac gattgctaaa
    31261 cgattttggc acaatttttt aagttgtgtc acgtatatca cttctctcta ttcacatttt
    31321 ttcttatttt gctcctgaaa aatgaaaatt tcctaaaaaa gttgttatct taagattttt
    31381 ttattctttc taaagattat tccgtccact tttcacagca taaaaccgct gcgatgtaag
    31441 cgattaaact aatgaagaga taaaagtctt gtggtgaccg cttcactcca cggtattcaa
    31501 aagccagttt ctcggtattc gtacaaaaaa agaggctgtg acaaaattct tgtcgcagct
    31561 ccttatttct tgatgcagga cagctttttc acaacttctt ccttaaacgg tgttctcctg
    31621 ccaactcctc ggccacaagt cacaatattt ataaaacatg agaagctgtt ttttgaaatt
    31681 gttccttgtg gctcagagtt aaacggcagg ctcaagacct cttgatacac ggtgttcaat
    31741 cagctgaccc tcggtattag attatgtcag gacgctaatt ttacaacctc ttggtaaacg
    31801 gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa acgaaaaata taaggagcta
    31861 ttttttgaaa ttgctccttg tggctcagag ttaaacggca ggctcaagac ctcttgatac
    31921 acggtgttca atcagctgac cttcggtatt agctcaaaaa acggcaaaat atgaggaact
    31981 attttgccgt ttgtttctct aatactcagg tcaaaacgct gatttcacaa cctctgtttt
    32041 tcattgtcca taggattgat attgtccttg tgatgactca ttcgtaataa ttgaggcttg
    32101 attttcttca cttcccgtta tcgtttgtcc actgccagaa tctgaaggac ttgttcctgt
    32161 cgactcgttt ttttgagaag agacagttgt tttcttgact tgttcatttg tctttttcca
    32221 ttccgctaaa cgatcggcga ccactttttt gtctactttt tcagaataag cggtgatcac
    32281 ttttccattt ttcaaacggg ctactttgtc gccatcatga gtcaaaagca aaacggtcaa
    32341 atgcttgtct ttaaattgat attgtctgag agaaatcgca ctaagtacgt catcgatatt
    32401 aataaattga ttttcttctt ttccttttgg caaataaatg tccaattcgc ctttttcgta
    32461 attggcagtt attttatact ccgcccacca ataagttgag aattcttttt tgaaattatc
    32521 tactgattct ttgcttgcta cgattttttc tgtttctttc tgagcaagat ctgctgtcat
    32581 ttttcctgaa aatgctgcgg ataaaataag cagtaagaaa aaaccgaata accaaaagag
    32641 aagaaacggt ctttttttcc tcatgctttc ctccactcct atttaatttt gactattcta
    32701 ttatatacaa aaaatgaaat agaaagacaa aaaagttgaa aaagatcgta aataattgaa
    32761 cttctttttc acaaaatggt aagaatggag aatttcacgc atttgctctc aactattctt
    32821 tcttaagcct caaatccgtt tttatctgat acgtctttga accaatgacc cgattttttg
    32881 attgttcttt ttccatcttg tgctaagtct actgaaataa agccatatcg attcttatat
    32941 gcattggtcc acgaccagtt atccatacat gtccacatat gatagcctaa acaattggca
    33001 ccttcttgaa tggcttgatg gacatatttc agatgagatt ggacaaattc gatccgataa
    33061 tcatcgtgga tcatgccatc ttctttgata aatcgtgctt cgttttctac acccataccg
    33121 ttttcagaaa taaagcagtc gatatttcca taatgatctc gtacattgat caaaatatca
    33181 tagattcctt gttcatagat ctcccatccg cgataaggat tcattttacg accaggcatt
    33241 tcataattgt cgaaataatc ctcaggcatt ggaccgtttt tagtatcgat tggtgtttct
    33301 tttgctttta cccggcgtgg ctggtaataa ttgataccta aaagatctac tgtattttct
    33361 ttgataaccg tcaaatcctc tgcatggatc acaggcatga gatcaagttc ttttactatc
    33421 tcaatcaatt cacttggaaa ctcgcctttt acagctggat caaggaatga acgattgaag
    33481 aacgcatctg ctatttgcgc tgctttaaca tcttcagggt ttgattcgtc tcttggatag
    33541 cttggtgtca gattcaagat gataccaata acaccacctt gctccatttc atggtaagat
    33601 ttgatggcta acgctgaagc caacgcttca tgatagccaa cttggatcgc ttttttcata
    33661 tctgactctt ctggataatg ccatcgatat aaataacctg cttcgactgg aacgattggt
    33721 tcattatgag taaaccattt ttttactttc gaaccaaaca attcaaaaca acttttggca
    33781 tatttttcat aggcttcaac cgtttctcgg ttcaaccatc cgcctttttc ttgcagatac
    33841 atcggcatat cgaaatgata cagattcaca aagggttcga taccgttttc aatcaactca
    33901 tcaaaataac gatgatagaa acgaacggct tcttcgttga ttgttccaga ttcatcaggt
    33961 atcaaacggc tccattggat agatgttcga aatgaattat gcccagtctg tttcatcaac
    34021 tgtacatcct cttgatactt cgtataaact tgcgaggttt tttcaggtcc tacttgatca
    34081 aagaactttt gcggttcttt tttgtaccaa taatcaaaaa tgttctctcc ttttccatcg
    34141 cctgaaatcc ttccttctgt ttgtgggcca cttgctgcag aaccccacca aaaatttgct
    34201 ggaaattgat attttttcat caaagcacct ctttttcttt tttagttcgt tttagttgat
    34261 tccatgtatg atattttcca tcacaatcac tttttcattt tcttcctctt cttttttgat
    34321 tcgttttaac agctgttctg ctgctcgttc cccgatttta tctgttggtg gcgtgatcgt
    34381 gattttcgga aggatactca gatcgttttt atctaaataa tcatagtgac tgaacgcaat
    34441 atccttcccg attctgacac cttcttgatt gaaacattcg atggcaccaa tcgacatatt
    34501 gtaattgctg acaaaaatag cagttgcccc tttttctaat aatgcttttg ccccgtaata
    34561 gccgcttttt ctagaatagt ctcctgtaaa gacctctaat tggatcgatg gatcattttg
    34621 gaccgcttct ttggctcctg ctaaacgttc tcttgctacg tagtctgttt gagtggcagc
    34681 aataaatccg atttttttat gtccttgttc accatgatga gcgatcactt ttgctacact
    34741 ttctcgatca ttcactaata ttgtatcaat acctgctggt ccttctggac aattcaatgc
    34801 gataactgga atactcattt ttgtgagcat ttcaaatcca gaccactctt cttcggataa
    34861 gaagacaatc agcccatcga tcacatgctt catcaggtat tcaatttttt gttcaatttt
    34921 ttctggctga tcggcaaacc cgcttaataa taagctatac ccattttctt cagctactct
    34981 ttcgatccct gagacaactt ccgacccaaa acggctggaa atcccgttta tcaaaagtcc
    35041 aatagagaag cttcgattat tcttcaaccc tttagcaatg atgttttctt tatagtccaa
    35101 cgctgaaatc gcttctgcta tttttttcat gttcttttcc ttcagttgct gaccattcaa
    35161 gtaacgggaa actgttccca ctgaaacacc agccatctta gccacatcac ggatcgatgc
    35221 catacattct cactcctgcc agttacattt gatttctctt tcttgttgtt cgattatgat
    35281 gaccgcattc tttgcatagt gttgcttgtc atcaatatcc atataactaa agtcttcagt
    35341 agagcaactt cctctcacta ttaattatac ttaaacaagt atttgaaccg gttcattttt
    35401 aatatagcat ttttttaaaa gattgcaaca cttttttaaa acgctttctg aaagtggcgg
    35461 attttttgcc tttttaaaat tttattctaa aatttactct atttgtgggt gttttgtgcg
    35521 tttttctctt ccatccgttt gaagttttac attccaatgg tataatttct ttatcctatc
    35581 aaatggggga agtattttga agaaattaat cgtactattt attttgtctg cgggactttt
    35641 gacattgact ggctgtgatt tgtttggcgg ctctgaccaa tcctcggacg aaacaaccga
    35701 ttcttctgtc ttaaaagcgg aaaaagcaga taccaccaac agtgtatata cgctaaaagt
    35761 acgtaaagat atggatttat ccgcgggaca gttgacattt acagataaaa aaatggaatg
    35821 gacacgcacg tatcagacac aaggaactga ttcttctgaa tcatctgaag aaaaaacagt
    35881 gctgacagat atcaagatca ctaccaaaga tgacgaatat attatttcag gaaaagaaaa
    35941 taaaaaagaa acaacagtca tatttacaaa aatcggtaat taccgtttga aggatgagga
    36001 tggcaacatc tacagtctat agtgccgtct gttggatctt cttttgtttc tccccttctt
    36061 ttctgctata gtaaagaagc aagatgattg taaaggagac gaaatggatg atcgatagtc
    36121 ctgattattg tacatgtaat aacaacaaaa atatccatac agaatttaat gaccaaggaa
    36181 gcttgagcat atgcgacaac tgtcacaaac tagtcaaaga ttcatttaaa acatttgaat
    36241 cttatcctgt tcaaaattat gtaaaaagta gaagaagata aacaaatcca agcaaaactc
    36301 actatggctg atttttatga acttcaaact cagcttcttc ctttgatcaa gcttcatcag
    36361 taaaacaaac agtggatcat ttcagtttac aaatcaaaga gtaaagattt atttatttca
    36421 aatatttgaa tataaaataa ccaaacgata gaaaggctta ttctacatca cgtagtaatt
    36481 tttctttccc gtcgtttggt tttttatttt tagcctaatt cttgaccttt tgcatgctgg
    36541 ttatccgtaa aatattttcc agcaggcttt ccttccaatt cagctaattt ttcttggatc
    36601 tgacggatca ccttttttgc atcttctgga ttttctacaa aatcgaattt atccccatcc
    36661 acttgtattt taggacatac atcaaaatct tcataccatt gattatagcg ggtgttcaac
    36721 gtttcataat aggtatataa cgtctcatcg ctttctagct gttcatagtc acgcccacgt
    36781 tttttgatac gttctagcat cgtgtccaaa gaaactttga tatggaccat caaatcaggc
    36841 cgtttttttg gagcaacatc atctaactcg tttagcatcg tatctaataa gctatcgtac
    36901 tgctgtactt cgatatccgt tacccgacct aaatcagcgt ttagatggaa caacaggcta
    36961 tcttcataga tggatcggtc tagcacattg tcatcgttca ctaaagcatt tttcattgct
    37021 aaaaatcgct tgttcaaaaa gaagatttgc aataaaaaag cgtactgctc aggatttgaa
    37081 taaaagagcg gcaatacttc gttatcttcg acattttcat aaaatggttt agaatcaatc
    37141 tcttttgcaa gcatatccgt caaactgctc ttacctgcac caatcgttcc tgaaatcaaa
    37201 atcactgaca tacaaccctt cctcttctat aagtactcgc ctacgtaagt ttcaacaggc
    37261 aatgtttcaa aatcatattc acgtacagct tggtctgatt ttaaatacgt atggagactt
    37321 tgtgtaatca tcaagttcgt aggtaccgtc tcttcttgta caatgatcat cggttttttc
    37381 aacatagttg ccacacctaa ttcgtaagcc gttcctggat cgattgtttg atgctcaaag
    37441 tcaaggatag caacaacaaa ttctgcattt gtcagttctt ccatatcttt ttcgtatact
    37501 tcctgcgccc atccagcgct gaatagttca taattgcttt cttggtgatg acgtggagag
    37561 tagaaacttg tgactgtttt gttttcctcc aacgcttttt cgatacgact tactcgatcg
    37621 atttgctcct ctgaaaaaaa tggtcctgct aaatatattt gactcattat tttgcctcct
    37681 tcaataataa ctgattttta atagatactg ctcgtaattc attgaccagt tccaatggat
    37741 tgttggaaaa gattacttga tccaaccatt ttttatccat aaaatcctct tttgcaaaag
    37801 tttctaataa ttgttgcaag ccgctgtaat aaccgccaat attcaatatt ccgattggct
    37861 tgtcgggcgt cagaccgatt gctatccaag aaagaagttg tgagaattcc tccaatgtac
    37921 ctagacctcc agggaaaacg aggacagcat ctcccttttc aaataataat acctttcttt
    37981 catcgatcgt ttctgtagga ataaatgtag taacatcttt tccaggcaat tcagtttcaa
    38041 aaagcccatt cggatagata cctgtgactt ttccgttatt ttccagtact gttttactaa
    38101 tcactcccat aatcccggag tatgaaccac cgtaaaccag ttcgatttct tcttgtgcca
    38161 tgtattttcc taacgtttgc gcaataaatt tgtaactttc tttattacca aaacgggaac
    38221 cgcaaaaaac agtaagtttc ataaaaaaac actccctaac tcaaaagtct atcttcattc
    38281 tacacgtgtt tttttaaaat aaaagactag attttgtagt tttttagtgg tatataggat
    38341 agacgccact atatatagta tttagaaaaa aatcattttt cagccatttt atagataaaa
    38401 caaaaataaa taacgtgttt tcatcgatat gaaatgactt acttatagaa gatactggga
    38461 tttcgtccta tatgccaata acgtgtatta ttttaaacaa caaatacttg tttcttttat
    38521 taacgaaaaa atcattttgt tctcgtgtta tgtttcactg ataaatgatg tttctctaaa
    38581 taaaaaagcc gacgaactaa acgatcaaaa tttgatcatt tttgttcatc agcttctcct
    38641 aaaaatcttt ttgttaacga taaatagctg gatttgtaaa aatatcactt gaatcgtcac
    38701 tgctggaaga aaattcagtg ataaccgcac ctgttgcgcc tgcctggaac tagtgtttga
    38761 tattgggctc gaacgtgtac tgatctctag catgaagaat aatttctttt tttactgtat
    38821 aataactttc tttccttttt ggaatagtac aggaaagttt ttttgtttcc tttccttcga
    38881 cataaggtat accagaccct ttcgacaacg aaaggttctc atttttcctt catcgtcatt
    38941 tcaaggaggg tgccgatgct ctggacagtt tcgatcgctc ctaaaccaaa atctgtatat
    39001 tcgattcttt ctaactctga ttctttcata ccattcctgt ctcaaggtac atctattgta
    39061 cttttttctt gtaatccatt ctgcctctcc taactaattg tcaaatcatc ccaagatatg
    39121 tcttcttcct ctttttcttc ttggatgatt tctgcattcg gatctactgg ttttttcaat
    39181 aataaaatgg ttattcctgt gacaaaagaa ccagctaaca atgcaccaat gaatgcccat
    39241 ggtctggtca tcgtagcgac tgcaaacatt cccgatgccg gaatacggct atctgcgccc
    39301 caaaacatgc ttaatccgcc acctactgtc ccaccgactc ccgttgctat gacattgcgt
    39361 gccaagtcgt tcaatacgat agggaaacat ccctctgtga tctgacagat ccccatagga
    39421 aaagcggtct tcaatgtatc gatttcttga cgattgagta tatttttacg aatgattttc
    39481 cctaagaaat aagcgatcgt caagccgaat ggggttacca tcgaagctaa aatcaataca
    39541 gtgattggtt catagattcc ttctgaaaat cgtgccacac ccccttatcc agaataaatg
    39601 gtaatccaga aacagccgtg tatctgcggt aataagccta accaaacgaa aaatatgaga
    39661 agctattttt gtttggctgt tcttattact tgatgcaggg cagctttttc acaacctctt
    39721 tttttattta tgtttcataa tcaatatggt aaggatgcag ctccgtatgg tagaccgcct
    39781 ccgaatattc aatcatttcc ccaatttgcg tagacgattt ccgtatccgt ttgatgccga
    39841 tctgtgcgtc tgttttcaga attccttgtt cttcttctgt taaaaatact gccgagaaat
    39901 catcagaaaa tgagtcaata gtatatcctt ttttcgtcag caaacgatac aaagattctt
    39961 tgccaaattc ttctctgctg aattgcatca tttcttgtgg aagataatga acaaaataaa
    40021 tataaggctg attgttcaaa taatataagc gcttaaaaca aacagcttgc tcaccgaaaa
    40081 aggaaaacaa aggatcttcc ttctttatat ggaccaattg caaatccagc gtttctttcc
    40141 ggacttcata tcgggagttc tccaagattt gcgtaaagct tgccgctttg gataatcgat
    40201 tgtaaggacg attgcttaga accgtcgtcc cacgaccact tttctttgcg acatattcat
    40261 ctgatgccag cagttcgatt gcctttcgga cagtgatttt gctgacttga aacagttctt
    40321 ctaattcact ttctgtcggc aacatcgaac cgactggata ttttcctgag aaaatatctt
    40381 ctttaatttt atctgcgact tccaagtata gtacacgtgt ccttttcata acgtcaccct
    40441 ttgctttact attactaaaa gaatagcaca taaaaaataa aaaaagaaca caaatcacat
    40501 gtgagaagtg tgttcttttt cattcagctg ctttaattac aagtttacgc catttgaggc
    40561 aattacttct ttataccaat caaaagattt tttctttgat cgattcagtg tcccatttcc
    40621 ttcatcgtct agatccacat agataaagcc gtaacgttta ctcatttctc ctgttgatgc
    40681 actgacaaga tcgatacatc cccaaggcgt atagcccatc aaatctacac cgtctgctac
    40741 tgcattagcc atcgcttcga tatgacgacg taaataatcg atccgataat catcaataat
    40801 cgtgccatcc tcttccatat gatcaatggc tccaagaccg ttttcaacaa tgaataatgg
    40861 tttctggtaa cgattgtata attcattcaa tgcgattctc agcccttctg gatcgatctg
    40921 ccagccccat tcacttgcct caagaaacgg attttttact cctcccagca agttcccttc
    40981 tgaagttgct gcttgtggat cagtctcatt gattgccgta gacatataat aactaaatcc
    41041 gatgtagtcc actggatatt cttttagcaa ctggaagtct ttttccgttt gctctaattt
    41101 ttccggatcg actccatatt ttttatgggt acgcgctgtg tatgcagggt attctccacg
    41161 tacttggaca tccgtgcaga aaaaattgaa ttcttggttt tggatcattg ttgctgcctg
    41221 attgactgga ttggcatcga tgctgtaagt tgttgcatag ataatcatgc agccgatttg
    41281 gatatccgaa cgcaattcgt ggccgatttt tacggctttg ctacttgcaa cgaattgatt
    41341 atgccatgct tggaaaatat tttggtactc tcctgctcca ttgcttttta ctaatccttg
    41401 acttaaagct ggaaagtgaa aggccgaatt gatttcattg aaagtcatcc aatatttgac
    41461 tttactgctg tatctctcta atactgtctg agcaaatcgt tcatagaagt cgatcagttt
    41521 tcgatttttc cagccaccgt attcttttgc caaatgaaga ggcatttcgt aatgagaaat
    41581 cgtgatcaca ggttcaatat catattttaa gcactcatca atcagctgat cataaaattc
    41641 taatcccgct tcgttaggag taccttcgtc tccatttgga aaaattcgtg tccaggcaat
    41701 cgaaaaacga taacatttga atcccatttc cgcaaacaag gcaagatctt ctttgaaacg
    41761 atcgtaatga tcgattcctc gatgattcgg gtaaatatat ttttcttgat caatcgtcca
    41821 gtcaaattct tcactgccga taatcgcaaa gcgctgctta cctccaggca tagcatctgc
    41881 aacggatagt ccttttccgt ctcgatcata agccccttct aattgatttg gcagcagttg
    41941 ctccacccca taaaaatttt tctgaaaaac gtgattgcat cctgatttcc tccttatttt
    42001 acaattgcca gaacatcttc gtttgcaata atctcttttt ggtctaattc aagtatatcg
    42061 gcaaatgcat cagtattcgt aatgacaact ggagtgatta cgctatagcc agctgctcta
    42121 attgcttcga tgtcaaaacg aatcaataaa tctcctgctt tgacgagatc cccttgtttg
    42181 actaagatct caaagccatt cccatttaat tctactgtat ccatcccgat atgaatcaaa
    42241 atctccgctc cgtcagtcgt tgtgatccct acagcatgtc cagttggaaa aatagtcgtg
    42301 atctctccgt ctgcaggtgc aactagttct cctacttctg gatcaatagc gatacctttt
    42361 cccatcacgc cagaagaaaa aacttggtct ggtacttcac tcaatggcag tactttaccc
    42421 gttaaaggac tttttaaggt atgccgtgct gaagtaatcg gttttcctgc attcgcatgt
    42481 ttgttttcta attgattgtc ttgtgtttgt tcgtcaaatc ctaaaatcaa tgtacctacg
    42541 aatgcaagaa caaaagcaat tcctgtagct attactgcta ctgtcacatt tgactctaca
    42601 ccatccaccg tattaatgaa agtcggaatc gtcaataagc tgaccaaact gctggagaaa
    42661 gcttttactc cggaaaatcc gataatagct ccaccaatac ctccagaaat acaagcggca
    42721 atgaatggtt tcttcaaagg taatgtcaca ccatacacag ttggttcagt gattccaaat
    42781 aacgaagtca ctgtagaaga aatccctaat gctcgaagtt tcgtatcttt tgttcgcaat
    42841 gctacagcta aagcagcccc accttgtgcc aagatggctg gaagaagcat tggcatcaat
    42901 acatcaaacc catattgttc gatattcaaa aacatgatcg gtacgaatcc ccaatgcatg
    42961 ccgaacatca cgaatacttg ccataaactt cccatgatta gacctgctac gattggacta
    43021 aatccataaa tcgagttgaa gagaccgcct aaagcattac cggcaaccgt cccgattggt
    43081 cctaaagcaa gaaatgttaa tggaaccatc actactaaaa cgacaagcgg aactaaaatc
    43141 atttgcagaa attgcggaat cacttttttt acgaatggct ctaatttact ttgaacccat
    43201 acggctagaa tgattggtat gacagaagaa gtataaccag atggtgaaag aatcactggg
    43261 atcccaaaga aactgatagc ttctcccgca ccagcaactg ctgtgatagc tggatacaca
    43321 agtgccatag caattgctac tgctaaaaac tggttggctt tgaacttttt agctgctgta
    43381 aaagcaagca tgacaggtaa gaaggtaaag acaccatctg ctgcagcaaa caatatttga
    43441 taagtaccgc tatcagctgt cagccagccc atcaccgttg ccaatgataa gaatcctttc
    43501 aataccccgg cggctgccat cgcccctaga aaaggtgtaa atatactaga gataatatcg
    43561 atcagacgat tcaaaatatt tttggactct tcttttccat cctccgaaac tgcaagacct
    43621 tcctcatcca cgatcgattg ataaacatct gctacattac tgccaatcac tacttgatac
    43681 tgaccgccac tttgtacgac ttggatcacg tccgggtctt cttttaactt ttgcgtatct
    43741 gctaaagatt catcttttaa tctgaatcgc aaccgcgtag cacaatgtac taaacttttg
    43801 acattctttt gtcctcctac cgcttcccat acacgacgac caactgcttg attatccatt
    43861 gttttttcct tctttctttt ttatttaaaa aataaaaacc cagattgaaa aaaacagtca
    43921 caaacattcg tgaacctatt ttttcaatcc aggttttgcc tgccatacag taacaatcct
    43981 tatgattgga tgcttttttt ctcacttact actctttgaa tatgaatcgt taaataaatc
    44041 tgctctgcga tccccatttc ctgtttttgc gtttgtcgaa gatactcatt gatccgttcg
    44101 acacaatgaa acgcttttgg atactttcct tgaactaatg cgtagagaaa ttcatcttgc
    44161 tcgtcagatc cttccccttt gagataacgc tgggcaaaaa actgcagatg agtaatgata
    44221 cgctgataat tcaaagattc ttcatcgaac acgatgccga agaatttact gatgatactc
    44281 agtatatctc ttaccattgt ggtagcggtc atcgtcactt gcatgtcttc gtttccttgt
    44341 tggctattca caaaatgaaa ggcaataaaa ccggcttcat cctcagaaag ttccacaccc
    44401 gtcttttgtt tcacgaacaa aagagcctct ttcgctgctt gatattcttt cggataaaat
    44461 ttttttgttt caaataataa tggattaggc agttggatat tttcttttgc tcgtgtgatc
    44521 gcataatgaa gatgatcggt caatgtcaga taaatattag gcgaaaattc aacttttagt
    44581 ttatcttcag ccagttcgac tacttgtttg acccattcga tctcctctgc cggaatatca
    44641 gccatcagct gctggaattg gtttttagca aaagaatctc ttaaaacaaa ttctttttgg
    44701 accgcttctg gcgaaatctc gtccccaatc tttttttgaa aagctagtcc ttttcccata
    44761 caaacgactt cttccccgaa tccatttttc gaaatgacga cattgttatt caaaatttta
    44821 tcaattttca ttttgcttcg ccctctcaag aaaaataaaa aaacctagaa ttcgcctact
    44881 gtttcttagc tgaattctgg ttttgcctgc cgtacagtaa caatccattt cttattcaaa
    44941 atcatcatac catcgaattt ttatttatgc aagccttttc atataaaaaa taaaaaaact
    45001 ggaacacaag tctatctaga aaacaaccaa atcagagatg cacctctttg cgtttctctt
    45061 tttttcagca aattggtttt tccttatcga ttcatatcct ttggctgttt ttaatctgta
    45121 acgacttatg tcccagtatc ctaaaatgtt tttgtctcta gattgaaagc agatctcata
    45181 tcatctgtcg catcttttat cgatgtaaca ctttccagtt ctccttgtac aactagtcgc
    45241 gtgacggcgt ccatgtcgcc acaagtaatt agtgtgacaa tttcttttcc ctcgacttca
    45301 ttcagtaatt gggtatctgt aggagcaact ttttctttaa aaaatgtttt gtatgtatac
    45361 acattttcta aatctgtcaa atagatcttg gcacccatct ctaaattttc tagcggtgta
    45421 aacagcaatt cagggttcgt tgcacgatgg cttgctaagg cataatttcc ttttcccatt
    45481 tcttgatctg gagataatgt tcctgctccg taaagtagtg acgtattatc caagcctttg
    45541 aaaaccggta aattgattga aactgaaggg actgcgatac tagcaatcac tggtagatct
    45601 gttcctctca tttgcgacct catgacccct tctgtcgtca ttggttctac cgcatcaaag
    45661 tcaaaactga catctttatc gttattcttt ttcagatctt cttttgttac attcgctata
    45721 gcatatttat ctcctgtctc tctgacaaaa taatccttga tctgttcatt gaaaatcaaa
    45781 gctagtccta ctaataacaa gaggaacaag aggatattga ctagccatct ttttgctttt
    45841 cctttttttt tcattttctc tccctccaga ctcattttac tgtttttctt ttgctctttc
    45901 caacagccga atgacacatt tctacaactc tgtgtatttt tttcgtacac ctgcgctttt
    45961 ttctacagga tatttcaaat tatttttgat caatttttct tcaatgatct catctagatc
    46021 caggtgaagg ttgtctgcca tcatgtatga atagatcaat acatctgcca gttcttcttt
    46081 gattcgttct aattgtgttt cttttacttc ttccggcgtt ttccattgaa aaagttctaa
    46141 caattcagat gcttccaaag aaatagagat agccaaatct ttttcgttat gaaattgtcg
    46201 ccaattacgt tcatctctaa actggttgac tttttccata ctattcattt gcttgccttc
    46261 ttccaatcac ttcttacttg attaatcata ccattttttt acataaaaaa tagatgatgc
    46321 ttttaaaaaa actcctgttt tcttttattt aaaataaatg tcatagaaaa tcaataattt
    46381 aggtagccac catgtgtatg cagtagcgtg tcttcttccc ttgaggcttt ttgtttttcg
    46441 atacgttctt cttcccaaac agacaacgct actagaatct ctcttaatga ttttccttct
    46501 tcggtgagcg agtactctac tttaggcggg acttggttat aggcttttcg atggatactt
    46561 tcatcttgtt ctaactctct taactgctgg gtcagcattt tttttgtgat cgtagggatt
    46621 tgcttgcttc tccacgccta aaataagcga tattgctctt ccctttatct ggtgtaagca
    46681 aagcagttag cattttgacg atcgtgggtt ccgcttttca cttcttatct acttagtatc
    46741 atgaagtata ctttcgtact aatactaagt agcggaagtg tcaactactt tgtttaacta
    46801 catagcaaaa gaaacagaag ggtgacaacg gtcatcacgc ttctgtttct tttgaatatg
    46861 ctgtgttgtt gtctctatct ccgtgtagac tttcctcaaa cttatccttt gacagtaagt
    46921 cagtaggctg atttgctctt tctagatgcc agatacattt ctacaaaaaa atagtgattc
    46981 tgttttgaaa attcgatttt tagttctgca ttttcgtaaa catccaacat ttttttcgca
    47041 ctgtatagac ctaacccgcc atttttttta gaggtttttc ctcttttgac catctccgat
    47101 agcgtcaaat tcgttggatt tgccttgttc gctatactaa aacgtgatcc ctctttttct
    47161 tccagcagat tgatcgtaat cggactctga tcggctacac gatgatcgaa tgcgttagaa
    47221 ataaaaatag ataaacagcg aataaaaaca accagatcaa tcgggattgt tttcacttcg
    47281 acaggaataa ctacttggat cgggattttc tccgattctg ctttttctag aaattttaaa
    47341 aagacacccc tgacagctgg ggatacaata tttgttagct gttgtatttg cggtttttca
    47401 aaaatagctg cagaatgatc ttctaatatt tctaaaaatt ccaacgtttc ttttttattt
    47461 tcctgaagag taatttttaa tgaaaacagt agacttttat aatcatgttt gaattcctct
    47521 agatgatggt aatattcttc atttatttga tacagttgaa gcgattcctg atgttgtctt
    47581 tcttttactt ggaaactgat caacataatg gaaaaaaaca aagaaaaaaa actgatgact
    47641 atcgacaaaa gagatagaag cagataatta gatgagcgga agtgaacact tcccaatacc
    47701 aagtaaatca cgccccagct taataaaata caaatacctc caaaatagtg ttcagttgga
    47761 taagtaaaaa gcaagttgag aaatctcgtc tgtttgtcta tactttttac taatagatag
    47821 aaaataaatg cgataagtag tgcaaaaaaa cttgctgttc caagatgtct ctttcctaaa
    47881 taatccatca gatcaaaaac cagaaaaaag ctgagtccag tgatagcaaa aaaaagatta
    47941 ctgatcaaac agctgataaa caggtttttc gtagtaaaat aaaaaagaaa catcaataat
    48001 aagccaacta ggtaaggaaa gctcacttta gggataggaa gtaaaagtgt caccaccatc
    48061 aaagctatac aaccaaagct gttttttact agcagttgtt tcgaaaagaa taaatagata
    48121 cctaaatcta aaatcaaagt aaaggtcaaa taaagtgtca ctgttgcgac catcttattc
    48181 ctccattgtt ttgtttcaaa atgtacacat atttttttaa taggagcctg catatgaaaa
    48241 agtattttat catagaagat aaccagtttc acagcgaatg gatcatcaga gaattggtca
    48301 atcatcatat cgagaatatc gtgcagctca cttctatctc tcaaatcaat cagttgatcc
    48361 agttgggcac tattgataat cacgatgttt tctttatcga tatcgacttg aagcaatcac
    48421 tcacaggtat tgatgtcgcc gaacaaatac gtaaaaaaaa tgcacatagt aatattgttt
    48481 ttttcaccgc ttatacgaat tttgcagtag agatcatcaa tcggaaaatc cttccgattg
    48541 gatatatcag aaaagacagg aatttatctg aacaaattcg tcaagtgcta gaacagatca
    48601 attggaaaga acagcagatc gtaaatgtcg ataaaatctt tattgatcaa aaaggtggaa
    48661 gtctcgtcct gtatcctcgg gaaattttat atattgaaag tatcaaaggt ttgaaaaacc
    48721 aagttatggt caaaacaact acagaagata aattagtgaa tacttcttta aaacaattga
    48781 agacagagtt agaaaagtat gcttactttt tacttttaaa atcttactgt atcaacttat
    48841 cgcaattgca gaaaattgat tctgctcatt atgtgttaga atttttcaac ggtgactcct
    48901 tactcgttgg tcgaaagatc tttgaaaaga caaaggaacg tttccatgac ttccaaaaaa
    48961 ctgcttcgag ttgatgaata agagctgaga cgtaagcata gcagatttca gggagtgggc
    49021 cttgaatcgg ctccactccc tgaaatcgtt gatatgattt tacgcttcct cttctgtagg
    49081 agcatctgtt aacgaccatg tgaatgttga aacgtagttg tctacagcat aattggatac
    49141 aggaacaaat aattccactg attgtctccc ttgttccaca ttctctccta atgaataaat
    49201 ccatgtgcca atcccttcat ttgctcctgc agttactaga tctactgcct gatctgctgg
    49261 gatttcgatt ccttcagcgc cagttccaga aacggtagat ggcattccac tgctattagt
    49321 tgcgctattt cgaatcacgg cgtttttgaa tttcaccttt gaaccagtta gtttattcgt
    49381 atcagatgtt gtaccaataa attctgttcg tttgactgat aatttccaac cggcataatt
    49441 tccgctttta tccgttactt gtacgaaatt ctgtacttgt gtttgtgctc cagtactgtc
    49501 cgttccgctt tgtaatgcag catatactgt ttttgctgta cctaacttga ttgttccaaa
    49561 atcaagatct ggagcttggt caatcgtcag taatccggat gttccctgat ttggttcgtc
    49621 aggtgtaaaa ggagtatcag gatcatttgg atcaacagga ggaactggaa caacgtcttc
    49681 aggatttgca gcatctggtt tggtcacaga aatcgttcct tctgtagtgg ctgagctctt
    49741 attctcagca aaaacacttt gtgtacataa taatagactt ccagctagaa cggtacttaa
    49801 tgcaattgtt tttttcattt ctttttcctt ctttctttta aaataaataa tccagcaaat
    49861 aagccaataa gaatgactcc aacaagtatc agccatcgcc agtcaaatgt ttctggctga
    49921 ttttttaaat caatatcctt ttcattcaat tggtccgctg catcatcagt tatttcaaaa
    49981 tcggtatgga gattccagcg tttttctttc caagcaccct tcacaaccgc ttgataatgt
    50041 cccggagcta atttttttcc ttctaatggg acaagtaaat caaaatttgt attgggtgct
    50101 acatctattt tttctttttt tattgaaagg taaggctctt ttgtttcttt tttgtagatt
    50161 tcaaccgatg tagtcaagcc gaacatataa gaagcatttg gattttgaag attcgcctta
    50221 atcacatttc ttccatcgct ttgatccgca taagcttttt ttaatttcaa atctggggaa
    50281 gactcttttt cgctatttca aatcaagatt gctttcactt gagaaaactg attgacgaca
    50341 ccaactgtac ttttgttaga aacgttctct tttttttctt gaaacgtgat ccctcctgcg
    50401 accacaccag ccagctcttt ttctggcgct ttcagtgaaa gtgtctcagt gaccgcactt
    50461 tgaggaggaa cagttatttc tcccactgtt tttgctaagt ttttcatatc ataacttaat
    50521 gtttcatcaa atttactttt tgattctcca tattcgatca caccgtttga attcgtcgta
    50581 gcggagtgga tcaatgtctc aactgttact gatttatctg ttcggttaaa gaccgtgtag
    50641 gggatttcct gtgttttccc aggctccatc cttacattta tatatgtttt gttcttatca
    50701 atctgattag ccggtaattc aaaatctacc gcaaaattga attcggaggc atggacaggt
    50761 gtctgccaaa ggatgaatcc aaggagaagg atcataagta aagagcagtt gtttcgatga
    50821 cttttattcc atattcgatt catcaatcat cctccttgat ctttattctg tcggcgcatc
    50881 tgctaatgtc catgttatct ctgctgagta attaccagct atctgatttt ctttggttaa
    50941 gacaagttta aacgcccgac cgttatttaa atattctgaa taatctgctt gcacattcgt
    51001 tgaattttgt cctctgacaa tttccagttc ttcttcattc actaattgat actcctctcc
    51061 tttcttgaaa tataggacat cctgcataga aaatcctgca tcatttgtga aaggctgaga
    51121 taattttatc gttaagatcc acggattttt cgtttctcgc tgatcataaa tccataattt
    51181 ttcctgtata tccatttggc caaatgcttc ttgtgtcaaa ccagttgctt tgatctgacc
    51241 aaaatcgagt ttggaagggg caagaaatga gagaccacct tctactacga tcttcgtagc
    51301 aggtgcaaaa ggcggggcat catgataaac aactggcgta tcacttggat tgtgattccc
    51361 aatttcatcg ttggtacttg gcttgttctg cacaccctta gcagtagctt ctcctgcttg
    51421 gtcgtttaat acaatttcta atacatctcc tgcaaaaagt tgattttctg ggatagaaag
    51481 aacaaattcc cctgtatcat caatagttgt ttctgacaaa acagcttgat tttttttcaa
    51541 tgaaaccaag gctcctgctt cacctgtacc tgtgatcgtg cgagaagctg cattgatcaa
    51601 tgtggtactt aaattagcag gttcaggagg aatcacatcg actgtcgttt tggcagagtc
    51661 cagttctgtc acttcttggc cacctcttac ttttttagca gcaacaactt gcacttgatc
    51721 ctccgttttt aatctctcat cattgggtac ttgaacttcg aacaagccgc cttgttcgcc
    51781 ttctccccat gggttatatc ctgccccttc attttcatct gtttgtcctt gcgtgagagc
    51841 agtaatttct acagatgatt tcgtcgtatc tgcgtaagta atacgtaaag tcacttctac
    51901 ttcgcctgtc caagcatctc ttggctttgc ctcgacacct tcgggaacaa cgacatgccc
    51961 atagattttt ttatctgcat tcgttggcac tcttaaggat tcaatcatcg ggagctgatt
    52021 attggcactg attcgattat aatttttcat tccggcacct gtctgagcaa attcatttgt
    52081 taaacctgca ctagggcttg atacgaaatt gcctaagtcg gtcccattga tcgataagtc
    52141 tgtcatatca gaaaaataat ccgggtcttt ttcaaagtta tcgaatgttg cgcctgtttt
    52201 tcgccataaa gcgatttctg aatgggcgat ctttaaagaa gaatctccat ttccttggaa
    52261 tacccagccg cctatgccat tggtctcgct tccaatccgt ttgttttgga aatcaaaata
    52321 ggtaggagat tctaagtcca cattcaacac atccccactg atgatgccgg tcttatcttc
    52381 ccctgttttc ccgaccatga ctaaataagt tttttcacct gccgtaaaat ttaaatcaat
    52441 atctccagtt gtatctacag ttgctccgga atctgcgcgt atatcgatat ttgatttttc
    52501 tccagtgact gtaaaatcag ctgaacctgg actttctaga aaaccagaag cgtcataaaa
    52561 ttggatcgct tgatttcctt gattgagtct gttcacgtaa gatttgccat cacctgtatt
    52621 tcttaccctc aatgagcctc cattggttac tgtcagcttt tgcgtaccat tctcaaaacg
    52681 aactgcgctg gaacgcccac tctgcttatc gatgtcgata actgatccgg ctccttctac
    52741 gatcaaagaa aggccttttc ctacaaaacg catcccattg ttcccgggtt gatcgtcatc
    52801 tccagccatt ttgaccgaga tttgtccacc acttgataca tggatttgac tagaatctcc
    52861 ttgcaagcga aatccgcccg tagttgctgt attgatggtg attttcccac cattcgatac
    52921 agtgactttc gatcctgaac ctctcatttg gatgattccg cgattgttgt cattggtaat
    52981 attgatcttt gtatttaccg aaaattcgct tcccgaacca ctgacttcaa acatgacatt
    53041 accaggtagc gtatcgactg cctctccttc atcgctaacg ccatctgccc gatcataatc
    53101 aagagagacc tttgaaccgc ttaagatatg gattcctggc gctgtttttc cactaccagt
    53161 ctcatctcct gaatctagaa aaccgtagaa tttccctaga tacggtccat aaagttgact
    53221 accattgatc acattcaatt gatagcttct acaaaaatag gctttacccg gagcggcatt
    53281 cagtccttcc ttcactggtt ggacatccaa cacaccggaa acaccatcta atgtgacagt
    53341 tgcacgagga gcgtaaatca gtcctaattt ggacccatca tacaaatcaa gtgtcccggt
    53401 aaattttatt tctcccgtaa aatgatatct gcttccccaa aaatcggtca tataagcaat
    53461 gataatggca tttccatcga tatttggtgt caatccacct ggatgtgcag ctgttccttt
    53521 aaaattctgg aactcgatcg actgaggtat ctcattgata taaatatggt gtgtgccgaa
    53581 attgtgagcg aatccaccaa aatcaataac gatatctcgt ttgatctcta attccctgtc
    53641 taaagtcaaa ggctgaatca gtcggatctt agttactgat tcgtctgcga gaagctgcgc
    53701 cagttcttct gttgtggcag cttcgctgta cccatccgct gaaacagctc ttgccagtgc
    53761 cgcttcactg ctatcagacg tttgttcagc tacttctgag gtctcacttg tcttattttc
    53821 ttcttgcctt ttattagtag aagcctcact ttgagattct gtagtttcag aagtaatcga
    53881 ttcttctgaa aaagtagtct tgtcaaaact ttgattctct gattgcgttg attcgtttgt
    53941 tttctctaca tcggcaaaaa cggatgtcac catcaagaga gggaagacaa acaaaatcga
    54001 cgcaatcagc ttttttacac attgattcat tctccaccat cctctctgac gttttgacaa
    54061 ttttatttta tcgttttaat ctatttccaa ttgtactttc atatttaaaa tatgtatttt
    54121 tatggaaaaa tttttctatt aggtgtaaat ttcttttttg tacaaaaaaa aggctgtgac
    54181 aaaagtcttg tcacagtccc ttatcccgaa caagcggtgt tctcccgcca actcctcggt
    54241 cacaacctcc attttaacaa taaacctgta aatgtgaggg caatactttg attgtcacag
    54301 gtaatttatc cccttcatct ccatcaacat tcgtcgtcaa ttcttcctca tcagctaatg
    54361 acacaactaa ttgctcacaa gtaaggtagg ctagattttt cgtagattca tctactcctt
    54421 ttaataggtc tggcaatgtt ttaagcgtat cgatcaaaga agaatctttt aaataaacca
    54481 aatggagctt accatcatcc acttttgcat ttggaagtaa tgtttcaaaa ccgccgactg
    54541 agttagttag tcctatcagc aaggtactgc tctcaatttc ttccttcttt ccatcaactt
    54601 ctacgtgaaa cgagtaggat tgtgtggaag ctaactgttt gattcctgac atgaaataag
    54661 ctagttttcc aaatttcgtc ttcttctccg catctacatc attgattgat tcagggatag
    54721 agccaattgc gacgacattc ataaaatagt cgtcatttat ttttccaata tccaatggct
    54781 tgactgattc aatcgaaaaa tgattgatcg cttcctcagg ttctagcggt atccctaatg
    54841 ctcgagccaa gtcattcacc gtacccaatg ggaaaaatcc gaaatttggc cgatgttctt
    54901 gttcagcgat tccactgatt ccttcgttga ctgttccatc tccgcccatg acaaacacac
    54961 tatgataccc ttccgtagcc gcttcgcgag taaagttttt tgcatcccct gctttttttg
    55021 tatgcaagac gaccacttca tcaaacaccg attccaattt tgctatcgct aattgctcaa
    55081 attcctttgc ttgttcaccg cctgaactgg ggtttaccac taataaaact tttttcatca
    55141 ctttctttcc cttctgattg atttctttaa tataacgata gcataaagaa aaaaattagg
    55201 ctgtgatgaa gtactgttca tgaaacattc atttattttt tgacaagata aaacatccat
    55261 actatgaaac tgaggaaaat taaaacaatg atataggaaa taaaagaaaa tgataggcat
    55321 tgtataccta ataaagtaaa aatcttaggt ggcagataaa aacacaaaaa tagcaagaga
    55381 atgtaatagc gtttcttcca ctttttgtta tcagacctta tagcgatcag aggaatacca
    55441 aatgcataac tgaaaaactc ttgatgtact gttaatatgt cacggccttg aataataaat
    55501 gcgacaatcc ccgctataat tagtgtgcct aacaccaaaa cggaaaattg atgaatatat
    55561 tttatataca aatgatccat tgtacttcct gcctttttat ttgtgagaaa aacaaatccg
    55621 tatacgtgaa taacttctag aaataaaaga aatttgcaaa accactccat ttatctactt
    55681 ctacgtgcat ttt
//
LOCUS       DACGDM010000010        54270 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.010, whole genome shotgun sequence.
ACCESSION   DACGDM010000010 DACGDM010000000
VERSION     DACGDM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.010"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            95..868
                     /locus_tag="IXR05_000665"
     CDS             95..868
                     /locus_tag="IXR05_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259208.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(949..1518)
                     /gene="thiT"
                     /locus_tag="IXR05_000666"
     CDS             complement(949..1518)
                     /gene="thiT"
                     /locus_tag="IXR05_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAQ4259209.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(1584..1686)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(1692..2663)
                     /locus_tag="IXR05_000667"
     CDS             complement(1692..2663)
                     /locus_tag="IXR05_000667"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4259210.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(2757..4130)
                     /gene="glmU"
                     /locus_tag="IXR05_000668"
     CDS             complement(2757..4130)
                     /gene="glmU"
                     /locus_tag="IXR05_000668"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAQ4259211.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(4633..5451)
                     /gene="purR"
                     /locus_tag="IXR05_000669"
     CDS             complement(4633..5451)
                     /gene="purR"
                     /locus_tag="IXR05_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAQ4259212.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(5618..6442)
                     /locus_tag="IXR05_000670"
     CDS             complement(5618..6442)
                     /locus_tag="IXR05_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4259213.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(6415..7095)
                     /locus_tag="IXR05_000671"
     CDS             complement(6415..7095)
                     /locus_tag="IXR05_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259214.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(7118..8056)
                     /locus_tag="IXR05_000672"
     CDS             complement(7118..8056)
                     /locus_tag="IXR05_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259215.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(8301..9152)
                     /locus_tag="IXR05_000673"
     CDS             complement(8301..9152)
                     /locus_tag="IXR05_000673"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAQ4259216.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(9306..11879)
                     /gene="mprF"
                     /locus_tag="IXR05_000674"
     CDS             complement(9306..11879)
                     /gene="mprF"
                     /locus_tag="IXR05_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4259217.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            12020..12826
                     /gene="proC"
                     /locus_tag="IXR05_000675"
     CDS             12020..12826
                     /gene="proC"
                     /locus_tag="IXR05_000675"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAQ4259218.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(12905..14461)
                     /gene="rny"
                     /locus_tag="IXR05_000676"
     CDS             complement(12905..14461)
                     /gene="rny"
                     /locus_tag="IXR05_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAQ4259219.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(14872..15921)
                     /gene="recA"
                     /locus_tag="IXR05_000677"
     CDS             complement(14872..15921)
                     /gene="recA"
                     /locus_tag="IXR05_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAQ4259220.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(16030..17271)
                     /locus_tag="IXR05_000678"
     CDS             complement(16030..17271)
                     /locus_tag="IXR05_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAQ4259221.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(17511..18089)
                     /gene="pgsA"
                     /locus_tag="IXR05_000679"
     CDS             complement(17511..18089)
                     /gene="pgsA"
                     /locus_tag="IXR05_000679"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAQ4259222.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(18298..19182)
                     /locus_tag="IXR05_000680"
     CDS             complement(18298..19182)
                     /locus_tag="IXR05_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4259223.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(19960..21246)
                     /locus_tag="IXR05_000681"
     CDS             complement(19960..21246)
                     /locus_tag="IXR05_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4259224.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(21239..22507)
                     /locus_tag="IXR05_000682"
     CDS             complement(21239..22507)
                     /locus_tag="IXR05_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4259225.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            22759..23220
                     /gene="mscL"
                     /locus_tag="IXR05_000683"
     CDS             22759..23220
                     /gene="mscL"
                     /locus_tag="IXR05_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAQ4259226.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(23280..23726)
                     /locus_tag="IXR05_000684"
     CDS             complement(23280..23726)
                     /locus_tag="IXR05_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4259227.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(23819..24064)
                     /locus_tag="IXR05_000685"
     CDS             complement(23819..24064)
                     /locus_tag="IXR05_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259228.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(24180..24758)
                     /locus_tag="IXR05_000686"
     CDS             complement(24180..24758)
                     /locus_tag="IXR05_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4259229.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(24835..25365)
                     /locus_tag="IXR05_000687"
     CDS             complement(24835..25365)
                     /locus_tag="IXR05_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAQ4259230.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(25369..26229)
                     /gene="rlmB"
                     /locus_tag="IXR05_000688"
     CDS             complement(25369..26229)
                     /gene="rlmB"
                     /locus_tag="IXR05_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAQ4259231.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(26222..26617)
                     /locus_tag="IXR05_000689"
     CDS             complement(26222..26617)
                     /locus_tag="IXR05_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4259232.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(26614..28026)
                     /locus_tag="IXR05_000690"
     CDS             complement(26614..28026)
                     /locus_tag="IXR05_000690"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAQ4259233.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(28023..28559)
                     /gene="cysE"
                     /locus_tag="IXR05_000691"
     CDS             complement(28023..28559)
                     /gene="cysE"
                     /locus_tag="IXR05_000691"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAQ4259234.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(28881..30341)
                     /locus_tag="IXR05_000692"
     CDS             complement(28881..30341)
                     /locus_tag="IXR05_000692"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAQ4259235.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(30511..31668)
                     /locus_tag="IXR05_000693"
     CDS             complement(30511..31668)
                     /locus_tag="IXR05_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAQ4259236.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(31702..33072)
                     /gene="radA"
                     /locus_tag="IXR05_000694"
     CDS             complement(31702..33072)
                     /gene="radA"
                     /locus_tag="IXR05_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAQ4259237.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(33135..33662)
                     /locus_tag="IXR05_000695"
     CDS             complement(33135..33662)
                     /locus_tag="IXR05_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAQ4259238.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            33892..34698
                     /gene="proB"
                     /locus_tag="IXR05_000696"
     CDS             33892..34698
                     /gene="proB"
                     /locus_tag="IXR05_000696"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAQ4259239.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            34695..35942
                     /locus_tag="IXR05_000697"
     CDS             34695..35942
                     /locus_tag="IXR05_000697"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAQ4259240.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            36018..36362
                     /locus_tag="IXR05_000698"
     CDS             36018..36362
                     /locus_tag="IXR05_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259241.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(36479..36805)
                     /locus_tag="IXR05_000699"
     CDS             complement(36479..36805)
                     /locus_tag="IXR05_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259242.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(37420..38622)
                     /locus_tag="IXR05_000700"
     CDS             complement(37420..38622)
                     /locus_tag="IXR05_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4259243.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            38739..39254
                     /locus_tag="IXR05_000701"
     CDS             38739..39254
                     /locus_tag="IXR05_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4259244.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(39453..39899)
                     /locus_tag="IXR05_000702"
     CDS             complement(39453..39899)
                     /locus_tag="IXR05_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4259245.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(39946..41424)
                     /gene="msr"
                     /locus_tag="IXR05_000703"
     CDS             complement(39946..41424)
                     /gene="msr"
                     /locus_tag="IXR05_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4259246.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(41778..42407)
                     /locus_tag="IXR05_000704"
     CDS             complement(41778..42407)
                     /locus_tag="IXR05_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4259247.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(42391..42855)
                     /locus_tag="IXR05_000705"
     CDS             complement(42391..42855)
                     /locus_tag="IXR05_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4259248.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(43342..44610)
                     /locus_tag="IXR05_000706"
     CDS             complement(43342..44610)
                     /locus_tag="IXR05_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4259249.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(44841..45578)
                     /locus_tag="IXR05_000707"
     CDS             complement(44841..45578)
                     /locus_tag="IXR05_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4259250.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(45645..46214)
                     /locus_tag="IXR05_000708"
     CDS             complement(45645..46214)
                     /locus_tag="IXR05_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4259251.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            46342..47214
                     /locus_tag="IXR05_000709"
     CDS             46342..47214
                     /locus_tag="IXR05_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4259252.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            47556..48428
                     /locus_tag="IXR05_000710"
     CDS             47556..48428
                     /locus_tag="IXR05_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4259253.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            48425..50383
                     /locus_tag="IXR05_000711"
     CDS             48425..50383
                     /locus_tag="IXR05_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4259254.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(50715..51566)
                     /locus_tag="IXR05_000712"
     CDS             complement(50715..51566)
                     /locus_tag="IXR05_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4259255.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            51689..52156
                     /locus_tag="IXR05_000713"
     CDS             51689..52156
                     /locus_tag="IXR05_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAQ4259256.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(52419..52901)
                     /locus_tag="IXR05_000714"
     CDS             complement(52419..52901)
                     /locus_tag="IXR05_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4259257.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(53001..53864)
                     /locus_tag="IXR05_000715"
     CDS             complement(53001..53864)
                     /locus_tag="IXR05_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4259258.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT        15512 a        11593 c         9673 g        17492 t
ORIGIN      
        1 tttgtaatgg aattttaaaa taaaagaaac aagctttttt aatgcaaatg ttgtaaaata
       61 aaagagatta agaggaaata agaggaggaa catgatgact gagtcagttt atgtacatat
      121 tgataccaca agtaatgctg ttttaacaaa agggctgact gctactgact ttgcaaacag
      181 tatcgtgcat tttcctcaaa acttgctctt gcttgatcca tctgcttctg ctggagaata
      241 tgaatcccat acagggctga aagtaatccg tggtacagaa aatattcagc gtttcttttc
      301 ctcttctcgt aacaggcgtg gattcgatga attgaagtgg atcgacttta ctgatttaac
      361 gatgctgaaa gaattgacac ctttagaaat ttcagaatta ttatattttg gtcatatgaa
      421 aacacatctt cattcgccgt ttttttataa actacagaat aattttgtat acttcgatct
      481 taatgatcag ctgaatcgga tttattatcg ctatttagat gaattttata ggatttttgc
      541 tagtaaatta agttcgatct tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa
      601 agaaacacct gttgaaaaaa tcagtgtgga attattgaaa gaaatgcgta atttgatgca
      661 ggaagggatc attttttctt ttgatcaagt tggtttgatc gatggtaaat atcgtatccc
      721 aatctatgtg attgaagatt atatttggaa attaaaaggc acccggtatc gagaagagga
      781 aatcatcgct actttaatct actctgtcac cgatcgacac tggcaattgg tagaagatgc
      841 cgatctttct tatctgccat tgaagtagat ctatttctta tcaaaaaata aaaaggaaac
      901 aagaaactag gacatgattc tgtctcaagt ttcttgcttc ttttttattt acagctcctg
      961 tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg atccctaata aaacgatgat
     1021 cgttacaata gctgtactca acccgctggc accattcatt acgaaagaaa agagccaagg
     1081 attcatcccc catagtgcat acgctcccca gaaaaccact cctgcaataa aatgccaaaa
     1141 atatctggaa agtgcgccaa tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt
     1201 attatcgtct acatagcctt tttggacatt tgaagccatg agccctgctg cgcctgcaaa
     1261 agtataggca atcgggtact caatcaacac ttgaacgaca cttaaataat aaacttgtcc
     1321 caacggaaaa tgtaggatgc cccaaatgaa acctgccagc atccctgcct ttgtccctct
     1381 tcttaacgca aaaagagtca atggaatctg ccctaatgaa atagaaaaac tgctgccgat
     1441 ctggatcgga atcaacgaca acaccatcgc taacgctgca acaatcgttc cttctaccca
     1501 aactctattt tttcccataa aaaaacttcc tcctttgaat aaaaaagtca caaaggagga
     1561 agcagctttc gaaaatagtc aaacagctgt ttattcacaa ttcctacgct cgcataaccg
     1621 atacaggtac gaagggttta gaaatagatt caatctcagc ccaattggac tcccctttgt
     1681 gagtttattt attatttatt ttttgtttca aacaatggac taactggttt gttttcatgg
     1741 atacgtttga ttgcatctcc cattagtccg ccaacactta cttcatcgat tttgtcgatt
     1801 ttacgatctt ctggaagata gatcgagtct gtaacaacta gacgctcgat agctgaatct
     1861 tctattcttt gtaaagcagg gccggataat actggatgtg tacatgaagc atacacacta
     1921 gttgcaccag cttctttcaa agcattggca gccaatgtga tcgtacctgc tgtatcgatc
     1981 atatcatcga tcagtacaca agttttgcct ttgacttgtc caatgatatt cattacttct
     2041 gcaacatttg cttttggacg gcgtttgtct atgatcgcaa tcggagattt caaaaattcc
     2101 gctaatttac gtgcccgtgt gacaccacca tggtctggtg aaacaacgac aacatcatcg
     2161 cctttgattc ctttttctaa gaaataattg gcaataagtg gcgcacccat caaatgatcg
     2221 actggaatat caaagaaacc ttggatttgg actgcatgaa ggtccaaagt cagcattctt
     2281 gttgcaccag ctttttgaat catgtttgct actaatttcg ctgtgattgg ttcccgtgca
     2341 cgtgctttac ggtcttgacg cgcatagcca taataaggca tgactacgtt gattgttttt
     2401 gcacttgctc gtttcagtgc gtcaatcatg atcagcaact ccatcaagtt atcattgact
     2461 gggctgctcg ttgattgaat aacatagaca tgcgatccac gaatactttc ttcaatgttt
     2521 acttgaattt ctccatcact aaattgagta acagatgatt ttcctaactc gacgccgact
     2581 gctgctgcaa ttttctctgc taatgggcga ttggaattta acgcaaaaat ttttaatctt
     2641 gggtcaaagt aatgttttga catggggacc tccactttct ttttcacaac tctagaattc
     2701 tacctaataa atagtagtca tattttttaa ataaatcaag tgattttgca aaagtcttag
     2761 tttagataag ggagtttttt tgcatatcct tctttattga cttgtcttgc tctcgcaatt
     2821 gccagcgcat attctggaat attgtctgta attgttgacc cggcagcaat cgaactgttt
     2881 ttagctacct cgacaggtcc gatgatattc gtgctagaac caataaagct gtggtcgccg
     2941 acagtcgtat gatgtttgtt ctttccatca tagttgacga agacaacacc acatccgaca
     3001 ttgatttctt ctcccagcgt agcatcacca acataagtca agtgaccgac tttagttcct
     3061 ttgccgattt gagcattttt cacttccaca aagtttccga tatggacgtt ttcgccaatt
     3121 tcagcttttg gtcgtaaatg tgcataaggt cccacatctg catgtttctt gacatggctg
     3181 ctttcaatga ctgagttttc aatgacgacg tgatcctcaa tcctactgtc tacgattttt
     3241 gaatgtgacc cgatgacaca atcagaacca atgactgtat ttccttggat ttgtacacct
     3301 gcttcgatca atgtgtctgg accgatttct acgcctgcat cgatgtatgt cgttgctgaa
     3361 tcgacaaagc ttacgccatt gaccatatgc atctggttaa ttcgctttct catgatctca
     3421 tttgctttag ctaacgcgat ccgatcattg actcccattg attcttcaaa atcatccgtt
     3481 tgataagcag caactgtatg gccttcttct tttaagattt cgatgatatc tgttagatag
     3541 tattcacctt gagcattgtt tgttccaact ttgcttaacg catcgaacaa agcttcgttg
     3601 tcaaaacagt aagttcctgt attgatttct tgtacaagag cttcttctgg tgttgcatct
     3661 ttttgttcca cgattttttc tacgatccca atatggtcac ggatgattcg tccatatcct
     3721 gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg cattttttcc ttggtgatat
     3781 tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg tatcgccact gataactaac
     3841 gttgttcctt tttttccttc caagaaagaa gcagcttgca aaacagcatg tcctgttccc
     3901 aattgttctg cttgtaacgc atatttactg cgttctccta gttgtgcttt aacttgttct
     3961 gctccgtgtc caacgatcgt aatcacttca tctggtttcg tttcactgac ccgattaatg
     4021 atatgttcta ccataggttt accagaaacg ggatgtaaaa ctttatataa ttttgacttc
     4081 atgcgggtac ctttccctgc cgccaaaata attgcataac gtgcgtccaa ctgcgtcact
     4141 cctaaatata gtttgctgat ttcagtttat cccagtatac ccattttttc aacaaaacaa
     4201 gtgattttct tttatcccag cgttttctgg ataaaaaaat agatagacca taacgggcct
     4261 atctatttgg taaccggtgc tctcctgcca actcctcggt cacaagtcac actactcata
     4321 aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt
     4381 acaacctctt cattaaacgt ttttcaatca gctgaccttc ggtattagct caataaacgg
     4441 caaaatatga ggagcaattt ttccgtttat tgagctaata ctcaggacag gacgctgatt
     4501 tcacaacctc tagataaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat
     4561 gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac tactcgaaac taagcggctt
     4621 tttcacaacc tcttattctg aaaaataatt tcctggcaca accgtaatat ttttcgtttg
     4681 agtatctaca tctttgacat aaagcagtga cgtataatca tcgatggcgc gatgaccgtt
     4741 gaattttgat tcggcaaata cagtgatgcc aacaagttct gattcgaatt cttcaatcaa
     4801 gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa tcatccacta caaggacacg
     4861 tgaaccacgt ttcaaacttc tcttagacag ttccatcttt tcaattcttt cagaagatcc
     4921 agacacatag ttgacactta ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat
     4981 aacgaatggc gcattcagat aataggacac agcttgggca ataggtacgc cttttgtggc
     5041 tacagtcatt acagcatcga ttttttcacc aaggtattta gaagcaatga ttcttccaac
     5101 ttgacgcagc agttcaggtt ctcctaacaa atcagagaga taaacatatc ctcctggaag
     5161 cagacggtct tgttctgata gacgttctgc tagagattca atatattttt tcgcctcttc
     5221 atatgaaatt tcagggatga acaatacacc acctgcagca cccgggattg tttccaaggt
     5281 tccataccct cgttctttaa atgttttctt gatgattccc aaatcttcac tgatagaaga
     5341 tttagcagat tcataacgtt cggcaaagct tgttaaggaa atcaattcat gcgggtgatt
     5401 caataaatac tgtgtcatgt caactagacg ttcactgcga cgtactttca cctattccaa
     5461 ctccttttaa gaaattttat cgttttacat tatataagtt tttcttcaaa aattcgagca
     5521 ttttatgaaa aaataagaaa atagttcggt atttattaaa ataaaaagaa gcctataaaa
     5581 aatttttcgt ttttataagg cttcttttct ttataattta gttatttttt cttctgaagg
     5641 caaccaatat tcgtttgatg atatttacaa tcaggaacaa agcaataaag actaatgtga
     5701 ttgttgctcc tggaggtgta tctagataaa acgagctagt tagtcctgac agcatcccta
     5761 gaaatcctac acaaacactg atagcaatca cgacattgaa gcttttgcct aatcgcatac
     5821 cgattgctgc gggaagaacc atgattgcgg atatcaaaag tgcaccggca atcgggatca
     5881 tcacagcaat agccacacca gtaatcacat tgaacatcat cgacatcaaa tgaacgggta
     5941 gcccatccac gtgggcggta tcttcatcaa aagtcagaac atacatcggc cgtttgaata
     6001 aaaagaacaa tataccgatg gcaacgaata agattcctaa aaagatgact tgctcccatg
     6061 taatggtcac gatcgaacca aacagatagg attggatact tgttgctgaa ttccctccgc
     6121 tcaaattcat caatactaac gctagcgcca aaccaccagc cattaaaatg gcaatggaga
     6181 tttctgaata ggttcggtag atcgttcgca gatactccaa tatcacagct gctaatacaa
     6241 cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa gaatcctaac gctacccctg
     6301 ctaaagagac atgagaaagc gtatcagcca tcagcgattg tcttctgatc actaaaaaca
     6361 cacctagcat cggggcgatt ccggcaatga agatagcggc aagaaacgct cttctcatga
     6421 attcatatga aagcaacgcc attgagaatc ctcctttctc accagtcgga tctgtctgtc
     6481 cgcatactgt ttgatatctt catgatcatg ggtgatcatt agaactgatt tcccatggac
     6541 atgcgcacta tgtcggagaa gacgataaaa ttcatttctg gattcttcat ccatacctgt
     6601 tgttggttca tcaagaacaa ataagtcagg gtcagtagca aaaatacgcg ctaaactgat
     6661 tcgctgcttt tgtccgccag acaattcacc tattcgccga tttcgcatat cccacatccc
     6721 tacagcttct aaagcacgct gtacatgttg atgatctttt tcagagagac gcttgaacca
     6781 gcggcctctt ggatatcttc ctgaacggac taattcgatc accgtactag gaaaacctgc
     6841 attgaaagat gcaacttgtt gaggaatata accgatactt aatttttttc cttcttgatt
     6901 tttctcagca atctttatca ttccttttga aggtttcagt aatcctaacg atgctttcac
     6961 caaggttgac ttggctgctc cattttctcc agttaaaatg acaaattcac ccgcatctac
     7021 atgataagag acatcttcta gtacaggttc atcatcatag taaaaggtca aatcagatat
     7081 ttcgatataa cgcaccttac aacctccatt ctaaaactta attgatactt tcttttaaag
     7141 ctttcagatt tttttccatg acagaaatat aattttcgcc tgctttgatt tgttcattag
     7201 tcaagctttc taaaggattc aacacttcta gcttcactcc tgtttcattc gacaatgtct
     7261 cagctacctt cgaagaggca ttttcttcaa aataaatcac tttgatgttg tttttcttca
     7321 caaattcttt tagctcagct aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg
     7381 aaatcgctac ttgttttaag tcgtattgat tcgctaaata agcaaaagca gcatgctgag
     7441 tgacaaatgt gcggtttgtt gcatctttta gctcatcgga gtatttttga tccagtgctt
     7501 caagcttttt gatataagca tcggcattct tcgtaaaagt ttccttttta tctggatatt
     7561 tttcgcctaa ttcttcagca atcgttctga cttcttttat agctaatacc ggatcgagcc
     7621 aaacatgtgg atcgtattca tgtgaatgac catgcccttc ttctgattct tcatgttcgt
     7681 ctgcttcttg cgattctaaa cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt
     7741 tgctatccac tgaatccttt aacgaatcca caaaaaattc catgtctgaa ctattataca
     7801 cgaaaacatc tgcatcggaa atttctgctc tttcttttgc acttggttcg aaatcatgcg
     7861 gctccgttcc agcagggatc aaaagtttca cgtttccttc atcccctacg atctcttttg
     7921 taaaatcata catcggataa aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt
     7981 ccttgttcgt atttccacat gctgcaaaca gtaaagcacc tatcattacc gtagctgtca
     8041 aaagatattt tttcatttat atgctccttt caatgaacaa atcggaattt tacgatttat
     8101 taacgtgaac taatgtatca aaataaaaaa acacagtcaa tagaaatcca tcaatttctg
     8161 atttaagcat gtatattctt gattaaatcg taaaatggat gagttgctgc tcatatctag
     8221 ccatttcact acaataaaaa actgaagaat accattttag gattcctcag tttttcatca
     8281 cctattttac ttcttatatt ttattgcagg gttcgtacta aataaacttc ctcacaaaaa
     8341 ccttttaacc cattatatac tctctgcgct cttgaataat gttgacacaa ggcaaaaacg
     8401 gttggtccgc ttccactcat caatgcagca tctgctccgt acttgatcat acgctctttg
     8461 atttgatgga tgactggatg ccgctttccc gttatatctt ctaaactgtt tcccattttt
     8521 ttgatcatct gctgataatc ttgctctcgg atggcttcag caagtccgtg gatgtcttga
     8581 tgttggatgg cttgcgtatc tacttctcta aacactgtac gtgtagagac actcattctt
     8641 ggtttgacca acacaaccca gcactgtggc atagaaggta atacttggat ttcttcccct
     8701 ttgccaccga caaatgccgt acttccgtag acacagtaag gaacatctgt accgacttcc
     8761 aaaccgattt ctgccagttc ttctaacgaa cagcccagat tccataattg gttgatccct
     8821 cttagagcag ctgcacagtc tgtacttcct ccgcctaatc cagctgctac tggaatattc
     8881 ttcttaacaa agatcttgac accggttttg atattgtatt tattttttag caataaagca
     8941 gcttgataaa cattgttccg ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg
     9001 attttgtctt ctgttatttc ttcaaaaaat agatgatctg ccaagtctac gctcgacatc
     9061 accatttcca actcatgata cccatcttgc cgtctatata atacatccag tcctaaattt
     9121 atcttggctg gcgctttttc aatcaattcc atcctctcac ccattcgaaa agtctaagtc
     9181 gcaagtattc tatcataggg aaaaataaaa gtatagctta tgtctgccta gtggttgatt
     9241 ttgtcatcgt ttcaacagct ttcacagaat tttctcttca taatccaaac aagttctagt
     9301 gattcttata attctgtgag cacttcttct gccaaactcg gaacatttcc tttttctttt
     9361 cctatcagac tgagtagctg catggtagca aatccgaaat tacttccttt cctataagca
     9421 aaataacgtc cttcccaatg atcgacatat tttaatttct tttcataagc agactggaag
     9481 gaatagaaaa aattaccata attatatacg atatgcatga ctttttcttg aaagaaagaa
     9541 aaatctgttt ctccaacatt agctaatgga gctaagccta gattggcttc cgagtagccc
     9601 attttctcgt atacaataaa cagattggct aacagatagt cagctaattc ctcagattct
     9661 ttaggtaaga cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg
     9721 atgaagccaa cgactttttg atctttacgg acaataccga caccgctaga taatacatat
     9781 gatttatcaa atcgtcccac agagaagtat ttttctcgtg caccttgaag ccatttttgt
     9841 gaaacttcat ttacagcttg atgtaattct tccggcagtt gatcgtacca agtaaaatgg
     9901 tatccttctt tcatcaaacg ttgatattca agttgctgac tcagccgaga caagtcttct
     9961 gttgctagat caacaatccc tgcttcacct actttcgtga agtgaaaacc caattcatga
    10021 agcatcacta cgtagctttc tgatatctta taaaacgcaa gctgatagcc taaacaatct
    10081 gcttgtttca taaactgatt cgttgctgcc cgcatcattt taggattgcc aactggatct
    10141 cctaaaacaa agcatttgtt tcctttgatc tgataaccaa aaacgacttg atcttggtcg
    10201 tcttcttggt aataaaaata actgtaacct gacaagcgaa gctgatggct tgtagctgtg
    10261 cctccgtatg tttccaataa acggtcaaaa cggtcttttt cgtactcact gccaagcttc
    10321 gtagtatctt cagctaaata ttgataaagc gccactaaag ctagcaatga gatgcccaaa
    10381 ccaataagcc ctgagaacca cacatcatct gaaggaaaca aaataaaatg atttcctgtt
    10441 attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa
    10501 aagccgaaca agctagcatc aaagattata gctccccaag aataaacgaa ttttgttcga
    10561 taaaattctt ttctggataa ccacacagct aacagaatca agacatatac caatatcaac
    10621 tgccaagata acgtacgtgt gattgtattt aaaataccaa aagatagtaa agcaatcgta
    10681 ggcagaaatg cctttttgac ttttactgaa agtgctctag caaggccgag taataaaaag
    10741 ccaaccaata gattcactgt ctgatctaaa aaattgaatg agaacggcaa taatacttga
    10801 aatagccgac tgattgcaga cagattagtg attgttgata gaagtaccat catgatcccc
    10861 gcaaaataga cagcacttac gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga
    10921 atgttatcta aaaatcgatt gattttgact cctgtatgtg tgatgaacaa tagaagtccc
    10981 gtcataaaag gtagaacata ataaaacaac cgataatata atagccaaac tactgctaca
    11041 tcttgccgaa cagacaattg actcattcct aagatcatca aaacgtcaaa agtccccatt
    11101 ccacctggga ccatcgtcag cattcctatc aatgtagcaa tcatgaacat aggatagatc
    11161 gaaagcatcg aaatatctat tctcatcaac ttgccgatga tcaaaaatac cgcaagggct
    11221 cccgtccatt gtccaaagga tgccagtagc agaccaagca agccttttgg ataaaactcg
    11281 aagaacaatg tctttctctt tagataagca aaaaagaaaa tgactggtgc taaaaaacta
    11341 ccgccgaaaa gccagatcca atagcttcga aaaatacttt ctgactgaat aaaaaagaca
    11401 tcaataaatg taagaaacga ccatacagac aaaccagtca gcataaatag tgcgactttt
    11461 gatacagtgg ctaaaaccat ttttctattt gtctgctttc cataaaaact agcccgcaga
    11521 cttgctccta ccacaccacc aaaaccggcg agattgttga tcgtgtttgt tacccacgca
    11581 gcaagaagaa actcttttct ttccattttt ggttttcctt gtttttctaa gactctgatc
    11641 gtcacccaat catacaacaa catcggagtg acacccagca gtccagccag aatcatgagc
    11701 aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa tatcttgcca actcatgcca
    11761 ttagcaatat ttgcgacttg atttgccaca aagactaaca cggagccgaa aaaaatcagt
    11821 tttaaaatca gactatgttc ctttatccat tgcagcatca agtatcgttt atttttcaca
    11881 ttttcccatt cctaacttgt atacttttgt gtcatacccc aatgttatct tatttatttt
    11941 aatttttcca ctttagacct gttctttgct tgcgatgata gaaaaagaaa gatatcctaa
    12001 tgctaaagga gaggataaca tgaaagtagg atttatcggc acagggaata tggcacaagc
    12061 tattattgat ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag
    12121 tggacatttt gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag
    12181 taatcaggaa gttgcatcac aatcagatat cgttctttta gccgtgaaac caaaaatcat
    12241 tgaaaaagta ttggaagaac taagagaata tagccagaaa gtcttattca tttctattgc
    12301 ttcaggaaaa tcattaatag atttagaaac agcgcttgaa gatcctcagg cctccatcgt
    12361 acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa
    12421 tgaagctgcc acggaggaac agcttcagca agctacgatg atttttgaag caatcggcag
    12481 cgtctatcct ttagcagaat cagatttcag tacattcatt ggccttgctg gcagctcacc
    12541 cgcattcgtt tacatgctga tcgatgcgat gggacggact ggtgtactga atggtttgtc
    12601 caaacagaca gccactgaga ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct
    12661 ttcaagtgat aaaaatccat gggaacttgt agaccaagtt tcttctcctg gcggtacaac
    12721 tgttgcaggt gtagttgcct tagaagaagc aggattcatc ccagcaatca tcaaaggaat
    12781 caatacgacg atcgagaaag atcttgagat gttgaataaa aaataatgat agcaatgttt
    12841 tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc gcggctcttc ttttgtattt
    12901 tttattattt agcataatca gttgcacgag tttcccgaat aacgattact ttgatgtgtc
    12961 caggataatc cagttcttct tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt
    13021 ctaaatccga gatttcttct ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg
    13081 cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt ttccagactt cttaaacgac
    13141 ggatgtagtt ttctaatgat tcacttcgcg caccaggtct tgctgctgag agcgcatctg
    13201 ctgcagctac aaggacagag ataacagaag tagcttccac atctccatga tgagaagcga
    13261 tcgcgttgat tactactggg ttttctttgt acttggcagc taattccgca ccgatctcaa
    13321 cgtgagatcc ttcaatctca tggtcaagtg ctttcccaat atcatggagc aacccggcac
    13381 gttttgctaa ttggatatct tcgccaagct ctgctgctaa gataccagct aattttgcaa
    13441 cctcgaccga atgcttcaag acgttttgtc cataactagt tctgaatcgc agacgtccga
    13501 tgatcttgat tagatctgga tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc
    13561 cgtattcgcg aatacgttca tccatttctt tacgagattt ctcgaccatt tcttcgatac
    13621 gcgctggatg gattcgtcca tcttgtatca gtttttccaa ggtcatccgt gcgatttctc
    13681 ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat
    13741 cgataccagt cagcgtctca agcgttcgaa tattacgacc ttctcgtcca atgatacgac
    13801 ctttcatttc atcattcgga agggtaacga ctgaaacagt cgtttctgaa acttgatctg
    13861 ctgcgcagcg ttgaatcgct aatgataata agtttttcgc tttgcgatct gcttcttctt
    13921 tggcacgctg ttcagattct tttaccatta gagttaactc atgattcagc tcttcttcag
    13981 tcgatttcat gatgacatct cgtgcgtcct cttttgataa accagcaatt ttttctagtt
    14041 ctttttgttg atcttcaatc attttttcaa cgtctttttc tcgctcttca attaattgct
    14101 gttttgaact aagtgcttct tctttacttt caagtgagtt ctcgcgtttt tctaacgagt
    14161 catctttacg attcagcgtt tgttcgcgtt gaatcaaacg attctcttga gattttaatt
    14221 ctaacttact ttctctcagc tcactttcaa cttcagaacg gtatttctga ttttcttcct
    14281 tagcttctaa caatgcttct ttttttagag tttctgcttc tttttttgca ctatcgatga
    14341 ttccagcagc tgatgattgt gcaccagcta tttctttctc gtgacgtgac tttgcgacca
    14401 taaaccctaa accaagaccg acaattaaac cgatgatagc gaggagaatg ttgaatacca
    14461 taaaatccac ctccatacta tctttttcat ttttatcatc tatacagctt ctatgataaa
    14521 ttattctaaa ctcgtcaata tgcatcttcg catatatgtg tacaaaaaac atgcacaact
    14581 ttattctaat gtttgtaccc cgtagtgtca actttaaata aacaaagaaa cggctttcta
    14641 cttattcatt aaacgatggt ttttaaaata aatgacacta gtttcatata ggtaaacctt
    14701 taaattgaga aacttttcta ttaaattatt ctttgtagat gaacagatat ttttatttta
    14761 tgtacccact cgtataatta aataactcac gatttcttta ttcaataaaa aaacggcagg
    14821 tcaaggagag tacctactct tcagaccagc cgtttttgtt tatcataatt tttattcttc
    14881 tactaaaggc aattcttctt gtcctttttc atcttctggg acagcgactt cttcaccaat
    14941 accataagct gctctaacta gagcagaaac ttctgccatc atttcaggat gattagccat
    15001 atagatttta gcgttttccc gtccttgacc aatccgatct tctttataag aataccaagc
    15061 accgctttta tcaacaatgt ctttttctac tgccatgtct agaagttctc cttcttgtga
    15121 gatccctaaa ccatacatga catctacttc agcgattttg aaaggaggtg ctactttgtt
    15181 ttttacgact ttgatctttg tacggttacc aacaatatct gtaccttgtt tcaattgttc
    15241 tgcacgacgt acttccaaac ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt
    15301 gatttctgga ttcccaaaca tcacgcctac tttttcacgg atttggttga tgaaaatagc
    15361 gattgttttt gttttgttga tcgaaccaga gagtttacgc aatgcttgag acatcaaacg
    15421 tgcttgtaac ccgacatgtg agtcacccat ttcgccgtcg atttctgctc gtggaactaa
    15481 agcagcaact gaatcgacta ctacgatatc tacagcccca cttgatacta aagcatcagc
    15541 gatctctaga ccttgttctc ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac
    15601 acctaatttt tgtgcatatt gcggatctaa cgcatgctca gcatcaatga aagcggccgt
    15661 tccgccattt ttttgtactt ctgcaatagc gtgtagtgca actgttgttt tacctgaact
    15721 ttcaggtcca tatacttcga tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac
    15781 atctaacgca agagagccac ttggaattgt agagatttgt tggtcgattt tttcgcccaa
    15841 tttcataata gagcctttac catagctctt ttcaattttt ttcagtgcag catctaaggc
    15901 tgctttacga tcatctgcca atacgataat cctccttata tttacaaatc agagcaacat
    15961 ttcattatcc ttatcatatc ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat
    16021 tcgcatttat cattttctta aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc
    16081 attatatctg atagcagcac gatctctggc aaagtgatat ttttccgaaa ccacgccgtc
    16141 tttagatgaa atagcgatcc atactgttcc tgcagattga ccttctaacg tgtccggtcc
    16201 agccactccg gtgaaagcta cactgtaatc tgttcttgct atctcacgtg cttgaatggc
    16261 catctgctcc acacattctt tgctgactgt tccatattct gctaatagct ccggatcaat
    16321 ctccagaaaa ccagcttttg tttggagcga gtaggtaacg aatccgcctg gaaatacttc
    16381 agatacacca gcaatgtcgc ctaatgcggc ttggaaggcg ccggctgtca aactttccgc
    16441 tgctgttaca gtctgcttgt tttctttcag tagttccact acgacttttg ctagcgaatt
    16501 atcatcgccg tatccataaa aatattcccc tactcgttct tggatttttt cttctaatgc
    16561 taaaagagct tgattccctg cctgaacatc atttgttttc actgtcagtc gtaatgtcac
    16621 ttcatttggt ttggcatatg gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt
    16681 tagctcagtg accagtcgcg attcaccaat cccataaaag cgcaaaactt tagaaattag
    16741 tttttcttca gaaggaaaac gttcctctag taaaggacgt acttgttcca caaacattgg
    16801 tttcaactca ttaggcggac cgggaagaag gatatacgca tgtgtatctg tttgataaaa
    16861 agtccctaaa gcaagccctg tacgatttgg tagaggaacc ccgccttcga taatctggga
    16921 ctgttgcaga ttgtttttgg tcatttttcg atgggttgtt tcaaaatatg ccaataattt
    16981 tttgtatcct tccgtatttt gtatgagaga cttaccgagg tgagccgcag ttgcttcttt
    17041 tgtcaggtca tcttctgtcg gtcctaatcc gccacataag agtatgagtt cacttcttgt
    17101 ttcagctaga gcaatcaact cttctaaacg ctgctgatta tctcctacaa ctgtttgata
    17161 ataaacttcg atacctagat cagctagctg ttctgacaag aaagtggcat tcgtattcac
    17221 gacttgtcct agtaaaagtt ctgttccgac agctattatt tctgctttca ttacttcccg
    17281 ctcccttata tagtatacgc tgtattttta tattttttta tttaaaaaga gggcaaggag
    17341 ctgtgacaaa aatcttgtca cagctccttg ttccaaataa acagtgttct cctgccaaaa
    17401 cctcggtcat aagtcacaat atacataaaa catgaaaagc tgttttttga aattatccct
    17461 tgtgactcag agttagacgg caggctcaca acctctccac taaacgatac ttacattgat
    17521 cctttgaaca caccgctgtt tttgatgaag taatccacac ctgaatagat agtaaagatc
    17581 agacaagcat aaagcatgat ttgatctact ggaataccga tcaggctgaa tgggatatta
    17641 ttgataaaca gcaagataat agcaaccatt tgtgtagccg tcttgacttt tcccggccaa
    17701 gctgcagcca tgacttctcc atgttcgaca agtagtaaac gcaagcctgt gacggctaat
    17761 tcacgacaga caatgatcgc tactacccaa ccaggggcct ttccttggtc aaccaacatg
    17821 ataaaagcag tcataactag cattttatct gccaacgggt ccgcaaactt gccaaaatta
    17881 gtgacaaggc ctcgcgcacg ggcaattttt ccatctaacc agtctgtgat actagctaaa
    17941 gcaaaaataa ctgcacctac tagctgtgtg acagccagtg tggtgtctcc tacgttaaat
    18001 tgtccccaat ctaaaggtaa acctacaacc aaaatgaaaa tcgggatcat acaaattcta
    18061 agtacagtta atttatttgg taaattcaca ctatcgactc ctttcttccc tattctacgt
    18121 gactatcagc gaagtttcca ccgatattat ttacttttcc aaatgaattt attcaaagga
    18181 gtatttttat tgaaattgat ctttttgaat taacgaagaa ggaccgcgac acagatttgt
    18241 cacgatcctt cttttttata cctacaagta aacagatgcg taaactaatt tatacgatca
    18301 ttctgcgtat tgaagagtaa ggttcacatt ttttggactc tgattgtttt cccctggatt
    18361 aactggtacg gattctccat tcgctttgat cgttgcattg cttgctgcac caatcgtgat
    18421 ggtcgcattt gttgctgttt ccggtaacac ggtactctgt gtttcatttg ctgccagtgt
    18481 cccttgataa acataggcat tgtctactag cacacctaac catacacgat tgacagcagt
    18541 aaattcaagg gttacaggct tggtagcgtc tgtgatattt actgcgatgg cactgccaga
    18601 atcttctcct gtagctattg ccattttctt ttcttcactt gattttgttg ttgattctac
    18661 tgtagaagac tctttggtct gcgtgctttg ctctgaggaa gaggactcct cgactgatcc
    18721 ttctacttta agcgaagaag ctgtgtctcc gattattgga tcagcttgac gatcttgcca
    18781 agtcatatag cccacgacaa cgacaatcgc caaagcaacc aatcctaata aaatgacagg
    18841 aagacttgtc caaaagcgac ttggatgcga ttcttcctga tgcattgctt ttctagaagt
    18901 acttactgtt tcaggctgcg gacgttcagg gaccgatcct gtcaatttgc ttttcccatc
    18961 aaaaacatcg actaaatggt ctccatcttc tcctacagct tcagcgtatt gccgaataaa
    19021 tgcccgcacg taaaatttac caggcaattg gtcaaaatca tcattgtcga ttgcttccaa
    19081 ataacgtttt tgaatttttg taatctgctg taattcatct aaagatattt ttttattcag
    19141 gcgtgcttgc cgtaattttt ctccgatggt ttcaaaagcc actcgttcat cttctccagt
    19201 ctgtttgatt ctccgaagca tctgctgttg caacgaaaga cgttatgttt gggtgctgtg
    19261 acaaaagtca tgtcacagct ccttttttcc gaataaacat tgttctcctg ccaactcctc
    19321 ggtcacaagt cacaatatcc aataaatata agaagctgtt ttttgaactt gttccttgtg
    19381 actcggagtt aaacggcagg ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc
    19441 ctcggtatta gctcaaaaac cggcaaaata taaggagata tttttccgta tgtttctcta
    19501 atactcaggt caaaacgctg atttcacaac ctcttcctta aacggtgttc aaaagcttgc
    19561 atctgcggta ataagtccaa ccaagttaaa aacattaaga agctgttttt acttggctgt
    19621 tcttattact tgatgcaggg cagctttttc acaacctctt ggtacacggt gttccagaag
    19681 tagcttcttc ggcaataagc cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt
    19741 ccttcttatt tcttgaagct gaccacttct gtcacaacct ctttgattac ttcgtttgat
    19801 tttattttaa tataagttga ttaaaagaga gcatgatttg ttttattttc tcactaattt
    19861 ttccaacaca actaagaata ccataaaagc tgattttgga ggaggttcct actacaagtc
    19921 taaaacgaaa tttaagactt ttcctcataa aatactggtt tattttggtc tcatgtaaaa
    19981 ctcgctgaag gcctcttcac ttataaatgc ttccccagct gccagtacgt ctttcatttg
    20041 gatcgaatcg atgatttcag gaagatcaaa taaagttcga tcgccaaata aactttgcgt
    20101 aaattgattg gcaatatatt cgatcgaatt taatgattgg aaatattgtc caagcatttt
    20161 cttcttcagc aaatcgagat ttgtttctga cacttccgga tcatcagcga atccaagaat
    20221 gatttctttg actttttctg ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc
    20281 aaagtgaaat tcacgatcca agctgaattc aaaaccaaag ctgtcatcga taattccttg
    20341 attgtacatc gctagatagt ttcgagaagt attgcctaaa atcatttgga acaacagatt
    20401 gattgctgtt ttatagcgta acagttctgt tccttcttgc ggcaatgtgt ctaatccttt
    20461 aataccaagt acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat
    20521 ttcttttgtg ttttcaggga aataacgtac aatttcttgc tttggaggga aattttttgc
    20581 ttcttggttt tcccgaataa gtttcatcaa tttctcaggc tccatcttac caactacaaa
    20641 taaaaccata ttgcttggct gataaaacgt ccgatagcac gtatacaagt cttgagctgt
    20701 gattttgtcg atactttcaa ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata
    20761 caagttattt agtatgccaa aaaacatccg ccagttaggg tcgtcttcat acatttggat
    20821 ttcctgaccg atgattcctt tttccttgtt tacagtttct tctgtgaagt aaggtgcttg
    20881 tacaaaatcg atcagagtcg tcagattctt ttctacctga tccgtcgtag aaaacagata
    20941 gctggttttc gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc caaataattg
    21001 aaagacatca ccatcttctt tttcaaacaa cttatgttct aaaaaatggg caattccatc
    21061 tggaactttc accttttctt tttcaccata gggaataaat tcgttatcga tcgaaccata
    21121 attcgtactg aacaaaccat atgtcttgtg atagtcattt ttaggcaaca aatacacggt
    21181 caaaccgttt ggcagtactt catgataaag tgtttcattg atttgctcat attctgtttt
    21241 attcatttgc atttcctcct gctaaaaaga agattgcctg caattcgatt tgctcagcta
    21301 cttgttgtat ctctttgatc gttacgctct ccatacgttt caaccattct tcatcagata
    21361 attttgtttc cggcagccag ctgtccaaaa aagaagcttc gattgccgct tgcggagagt
    21421 ctagagaaag cagatattgg tttctcagca ttgcttttgt ctgagacagt tccaactctg
    21481 ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt acttgatttc
    21541 ggttcttttc atcgataccg gtttggacac tcatgaatcc tcggaacgta tccacgctac
    21601 tagaggcata ataagctaga ctttctttct ctctgacatt catgaaaagt ttagagtgag
    21661 gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat
    21721 acacatttgt ctgataagct aggttcagct ttgcttgaac gattggctca cgtacttgtc
    21781 gttccttcac gatattcact tgaggttggg tataaaacag atctggataa actgtttccc
    21841 gcgactcaaa tggtaattgc ccaactgctt cagctgcttt gtccggatca acatcgccga
    21901 caacaaaaat gtcgatttga tcatttgcca tcatttcttg atagtaggac gctagcgaac
    21961 tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt tgttccgggc
    22021 tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa agtttgttta tcttccttca
    22081 aactttccaa atatagacgc agattgttct tttccaagtc aaacgtcaac tgatcaaact
    22141 gatgattttt aatatttgga taaaataaaa cctcttttaa aaaatctacc gcttgagaaa
    22201 aaaggtttgg atcattgaca tattcaccat tcacaaaact gatccctgcg tttagccaat
    22261 gtaaatttcc tttttttcta actgataatc caaagcttgc gccataaagc tctgcaagtt
    22321 gcgcacttaa ctttgtctga tccgaataat tcaaactatt tgtttccaac atgctgctga
    22381 gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc
    22441 ggatcgtttt gtattgtttt gttggtaaga catgaagatt cacgccttct gccaattgat
    22501 acaccatatt tatatgctcc ttttcacagt tgattgcccg cttactcttt taatgggtca
    22561 acctgccttt tttacttatt cctctgcttg aaatttataa gttcaggcaa ttcgccgttt
    22621 tttctaaatg atgttacact ttatagtata gcatagatgt tttttatcaa aagaaacaga
    22681 cggctaaaag cgtatattgt ttttttattt tttatttttc gatatactaa agacaaataa
    22741 aagaagggag ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc
    22801 ttggatcttg ctgtcggcgt tgttattggt agtgcgttta caagcatcgt aaaccaagtg
    22861 gtgcaaggct tgatcacacc actaataggt tggtttgtcg caatgatcac aggtacttct
    22921 gatttagaag gagcactttc aattcttgac tggtcgccga caaaaggcgt cacatttgcg
    22981 tttggtaacg ttattagtgc tatcattaca tttctgatca ctggttttgt cttattctta
    23041 gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca aagaagagca agtggaagtg
    23101 gaagaaactc ctactgcaga agattatctt agtgacatac gcgatcttct tgccaaacaa
    23161 gtggcagaag acaatacaca tccagtagag caaacaaatc tttccgatac ttctaaataa
    23221 taaagaatct aaaaaaaaag aaagccgatt ttcagtgtcg gctttctttt tttagattct
    23281 taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc caaatacaca
    23341 tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc ttgtgcgccg
    23401 atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc ttgaacaatc
    23461 tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc aaaatggata
    23521 ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt atcttgaaaa
    23581 aacgtatgcc aagcttctcc atcaatgtca tcaacttctt gataaggaca ctgttgttcc
    23641 acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt tgacaattct
    23701 tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt attcttagca
    23761 taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg tttgcttttt
    23821 aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct gaatagctgt
    23881 aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat actgaaggat
    23941 aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc tgagcaacca
    24001 acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct aaagttgttg
    24061 gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt caagtttacc
    24121 ataaaaaaaa aaagaaatgc aataaaaata aataagaagc tcattaagat ttttctaaat
    24181 tattcctcat tataaaattt caagtgtttt tttattttga gttttactct cccgtaagcg
    24241 ctcattactt gcttgtgatc cattgctaaa cattcagcca tgtctacaaa atcaacgcct
    24301 tgcatataat aatgaaaaat tttagcttct atttttgaaa actggatttc gcaattttcg
    24361 attgcttctt ttaataaaag atgctgaatt gctaaaggtt cttgcaatgt gatctctgct
    24421 aaaaagtctg gtccttctgt ctctattttt tggtcgattg agacttcatc tttttgatca
    24481 cgacgcttca gcgcgttctg cttcctcaac agagaataga tttgattgct tataacgctt
    24541 ttataataac ttccaaagct aacacctttg cttttttcgt aagttctcaa tgcctgatat
    24601 aaagcgatcc ttgcttcttg ttcccaatcc tcagaaacat aatttcttaa ataataggtg
    24661 tttttcaaac gtagtaaaag tggaaaatat ttttgataca gggcagcaaa tgcttcttcg
    24721 tcaccattac gtgcagcgcg caataactcc tcagacataa aataattcct ccataaattc
    24781 gtttatggag gaatcttatc atcaatgatt catcgaactg attagaacga tatgttattt
    24841 attttttctc attaaatcgt ccaatttttg ggacaatttt tttaactgct cttcattcca
    24901 tggagaatta cgtcggaaat caataaaatg catatcttta ttttcttggg ctattgtttt
    24961 ttccgttttt tttatcgtct tatataattc ataagcagaa gttcgtaatg ctccttggga
    25021 aaagatcatc cactgttctg ctaaatcgct tgtcgccact gtcacttgtg tcaaacggtc
    25081 attcagctga ccagcgattc tctcgatata actgtcagcc gtttcgtctt ctttcgtaaa
    25141 aacaacatcc aactggtatt tcttataatt ttgttggatg cccggaacta gttgggcatc
    25201 gaagacaacg atgacttcca ttccttcata tttcgcataa tttgataaac gatgtaaaag
    25261 agcttctctt gcatccgcca ttttgtcctg ctttttaagc tggacaagtt ccggccacga
    25321 accaatcatg ttgtagccgt ctacaatcaa cagctgtttt ttcatggtct actccccctg
    25381 acgttgggaa aaagcctgat acataagcaa accagcagca acactggcat ttaagctctg
    25441 gacgtgcccg gtcatcggga tcgtcagcaa ttcatccatt tcttttttca atcctggact
    25501 cattcctttg ccttcattac caatgactaa agcaattgat cctttggcat tccatttttg
    25561 gaagtttgtg ccggtcatat ctgtgccaaa tacccaaaat cctgtttctt tgagctgttg
    25621 cacagcttgt accaaattcg tcacgcgtgc aacagggaca tgttcgactg ccccagtgga
    25681 agtctttgtt acgataggtg tgattccaac tgctcggtgt tttggtatga tcacaccatc
    25741 gacgccactt gcgtctgctg tccgtaaaat cgacccaaaa ttgtgtggat cttcgatgct
    25801 atccaaaatc aaaaagaagg ggtcttcttt tttctctttt gttcgttcaa tcagttggtc
    25861 aagggataaa tattcataag gtgtaatcgc aagaacgact ccttgatgca cgccgtgatc
    25921 gctcaaagtt tctaattttt gtttaggaac ccatttgact ggcacagctt gttcacgtgc
    25981 gatttctttc agttcttcta ctttttctcc tcgtgaatct tcttgaagaa agagtttatt
    26041 ccctcgccct tgttgtagcg cttctactgc ggcatggtgc ccaaagacga aattatcttc
    26101 taatgcttct tcattttgat cagaaactga ctgatttcgt ccagtttgct ttttatttga
    26161 atatctattt tgttttttgt cttcaaatcc acgtttcgat tgatgtttgt ttgttctttc
    26221 tttacccatt tttttcacca actttctgaa tacaccagcg gatcaattct tccatccgct
    26281 cggtttgttt tgtcaaatgc agatagccca tgagcgcttc gaaccctgtt gcgacccgat
    26341 acgtcgtaac atcagcattt tttgcgctcg tatggctttt agcatttctt cctctgcgat
    26401 aataaagttc ttcttcttct gtcaaaagat gttcttccag catttgctga atcaaaaagg
    26461 cttgtgcatt cgcagaaaca taattcgttg ccgcacgatg cagcttattg ggttttgttt
    26521 ctccttgatc aatcaggtgg tcacgaacat agatttcgta aatcgcatct ccaacataag
    26581 ccaaggctaa accgttcaat tgtgtgtaat ctctcatgct tctcttctcc atcgggttcc
    26641 ttgcggtgta tcttctaata agatcccttt ttctttcaac aaatcacgaa tttcgtcgct
    26701 tcggacaaaa tcacgattgc ttcttgcttg atttcgttct tcgatcaatt gttcaatctc
    26761 ttcatctaat aactcttctg ctgtaaataa aataccgaag atcgaaagcc attgcgagaa
    26821 taaagcttct ccttgtgcca agacagcggc agaaactttc ggctggtcta gataagtgtt
    26881 cagccactta gcaagctcat agaccactgt gatcccattt gctgcattaa aatcatcgtc
    26941 catttcttcg atgaatcgct gttctaaatt ttctaacaaa gcgattttat ccgcatcatc
    27001 tgccaaattc tctgaggcag tttcttggcg gaatttcaaa ttgtcaaacg tattcttcag
    27061 tcgttgtaaa ttggtggctg cttctttcat cgtcgtttca ctgtagcgga tcggacgacg
    27121 gtattgtgtg gtcgccatga agaaacgcaa gacttgtgga tcaacgtttt tgatcatttc
    27181 atgtacagtg atgaaattcc ctagagattt actcattttt tcatcgtctt cgccaatcgt
    27241 tacatagcca ttgtgcatcc agtaattagc gaattttttc cctgttttcg cttcactttg
    27301 tgcgatttca ttttcatgat gaggaaattc taaatcttgc ccgccaccat ggatatcgat
    27361 cgtttctcct aaatgttttg ttgccataac ggaacattca atatgccaac cgggacgtcc
    27421 tttgccccat ggtgaatccc aagaaatctc gccaggtttt gcttgtttcc ataaagcgaa
    27481 atctaatggg tcttcttttt gctgctgttc ttcccctgta cgctgacttg ctccgacttc
    27541 cagttcatcg atggattggt cacttaattt cccataattt tcaaatttac gggtacggta
    27601 atacacatca cctgaagatt cataagcata gcctttttca accaacactt gaataaatgc
    27661 taaaatatct ggcatatgat ccatgactct tggatgcagt gtagcaggtt cgacattcaa
    27721 cgctttcgta tcttcttcaa atgctcggat gaaacgatca gcaacttctg gtgctgtaat
    27781 acctaattcg tttgctgtac ggatgatttt atcgtctaca tccgtgaaat tcgatacgaa
    27841 atcgacttta tagcctcgat attcaaaata gcgtcgaatt gtatcgaaag caatggtgct
    27901 acgagcattt ccgatatgga tataattata cacagtcggt ccgcagacat acataccgac
    27961 atgtcccttt tgtataggga tgaattcttc tttttttctg gtcaatgtat tgtagatttt
    28021 tatcattctg atctcctcac tttttctcct ttgattcgaa cgacttttgc tggtactcct
    28081 accgctgtag cgtcgtctgg aacatctttc aacacaacgg cacctgcacc gattttggcg
    28141 ttttttccga tcgttaccgg tcctaatatc tgcgcattcg cagagagcat ggctccttgt
    28201 ttaacagttg ggtgtctttt acccgtttct tttcctgtgc cgcctaatgt tacgccatgg
    28261 aataaaatca catcgtcctc gatttctgcg gtttcgccaa tgacgattcc cattccatgg
    28321 tcgatgaaca cgccagttcc aatcgttgct cctggatgga tctcaacacc agttaggaaa
    28381 cgccagaatt gagcattgat cttcgccaat aaaaagagcc ggtgctgata taaaaaatga
    28441 gagaaacgat gccaaaacaa ggcatgaaaa ccagggtatg tcaaaacgat ctcagctgtc
    28501 gaacgtgcag ccggatcgtt tctctttgct gcatcaatcg ctcgggtaaa ccaactcatg
    28561 actttccact cctttcgtaa gaattttatg taggaaatca tcttcttata aagaaaagaa
    28621 gcgcctttta aataagtttc cttatcaaaa gacgctttcc gcgtggttcc acttttcttc
    28681 ataatcaatg attatctctg acagctaacg cctgttatac gttcttggct actttgtttc
    28741 ctataaaaca gtttttcctg ttttctgtgt ttcgccaaga ccactcccag aggcatttcg
    28801 gcaaccattc attgatacct tgcaccaccc ggtatctctc ttgtaatgat cagctgctta
    28861 cttttttctg ttcatcgtgt ttagttcagt acttgattta aatgtgctaa tgatttttca
    28921 cgaccaagca attcgatcgt ttcaggcaat tctggaccat gcatttgtcc tgatacagct
    28981 acacggattg gcatgaaaag attttttcct tttacgccag tttctttttg aacagctttg
    29041 atggcagctt tgacagttgg agcatctact acttccattt gttctagctg tgctttgaat
    29101 gcgtggagaa cagtaggaac tgtttcacca gcaagtactt cttttgctgc ttcattcaat
    29161 acaggatgtt cattgaaaaa tagcgtagac agatcaacga tttctgcagc atagctcatt
    29221 tgaggttgat acaggctaac gatcttcttc acccattcga ttgtcttttc atctgggttt
    29281 tctgctacac gtccatcagc gattagataa ggcagacaca tgtcagtaaa tgcatctaga
    29341 tccattgctt tgatgtaatg gttgtttacc cattgcagtt ttttcgcatc gaaagctgcg
    29401 ggtgatttac ttaggcgttt tggatcgaac attttgatca attcttggtg ttcgaagatt
    29461 tcgtcttcgc ccacaggtga ccagcccaat aatgcaataa agttgaacat tgcatctggt
    29521 agatagccta attcgcgata ttgttcgata aattgcaaga ttgattcgtc acgtttgctt
    29581 agttttttac ctgtttcact gttgatgatc aatgtcatat gtccgaaggt tggtggtgtc
    29641 cagccaaatg cttcatagat catcagttgt tttggtgtat tggcaatatg gtcatctcca
    29701 cgtaaaacgt gagtgatttt catcaaatga tcatcgaccg caacagcaaa attataagtt
    29761 ggcataccat cgcgtttttg gatgacaaag tcgccaccga tattatcgga ttcgaacgaa
    29821 atagcgcctt tcaccatatc tgtaaatgcg tattctgtat tgcgaggcac acggaaacgt
    29881 acaacagatt ctagaccttg tgcttctttt tctgcttgtt cttcaggtgt caagttcgca
    29941 catgttcctg cgtaatgagg catttctcct cttgcgcgtt gtgcttcccg ttctgcttct
    30001 aattcttctt ctgtgcaata gcatttgtat gctcgattgc tagcaagcag ctgatcaatc
    30061 agcggttgat agatttcttt acgttcagat tgacggtaag ggccgtattc tccaggattt
    30121 tcaggagatt catcccaatt cattcccaac caagcaaggt tttccaactg gcttttttcg
    30181 ccatcttcga tattacgttt ttggtcagta tcctcaatac gaataataaa gtctccatca
    30241 ttgtggcggg caaacaaata attgaataat gcagttcttg catttccaat atgcaggtgc
    30301 ccagttggac ttggtgcata gcgtacgcgt actttcgtca ttttcttcct cttctttcaa
    30361 actagacttt gactaacagc aaaaattccg tcagttacgg cttctcaaat atcatttatt
    30421 taaagccact cagcacaaat tttacctttt ctaaggtaaa tagtaaagcc aactggttga
    30481 atttccttac cagttggctg aatttctttt ttattttgat tgtttagtct ttttctctgt
    30541 ctctttttta ttgtcgattc ctcgtcctgc atgtgcaggt ttagcaaaga tcatgcgtcc
    30601 agcagctgtt tgaagggcac ttgttacaac gacttcgata cgttcattca tgtaatgctg
    30661 tccatcttct acgacaacca tcgtgccgtc atcaaggtag gctactcctt gttggcgttc
    30721 tgtcccggct tttactacta gaacattcat cgtttcacca gggatgacga ctggttttac
    30781 ggcatttgcc aacgcattga tattaagaac aggtacattt tggaattcag agactttatt
    30841 caagttatag tcattggtta caatgacacc atctaaaagc ttagccaatt tgatcaattt
    30901 gctgtctact tcactgatat cttcaaagtc tccatcgtac atttcgacag atataccctc
    30961 ttctttttgc aaggcattta ggatatctaa tccgcgacga ccacgcacac gtttcaaact
    31021 atcccctgag tccgcgatgt attgtagttc gtaaagaaca aaattaggga tcatcaaggt
    31081 tccttctaag aatccagtct ttgtaatatc ataaatccga ccgtcaatga tcacgcttgt
    31141 atccaagatt ttatatttat ggaaattttc tcctgatttt cgttctaaca gttgactctc
    31201 aacttgacta gctgtttctt gctcgatttt tttgcttcgt gaaccaaaaa ctttcttcca
    31261 ttcttcgatt cgtgtcgttc ccattctcaa tcccagatag cctaagatga tcatcagtaa
    31321 aatcggcaat acactattga cgaatggaat ttccatattg taaagagggg tcgagatcac
    31381 aacacctaaa gtcaatccga tgatcgcacc gatcgcaccg aagagaagat aagtcaagct
    31441 gacctcactt agtttttgtt ctacttgttt gataatagct gagatatgtt tggccaacag
    31501 caaagataat aaaaagaaaa taagtgcgcc taacaggctg ttggtaaatg tattattcag
    31561 ccatccgttt gactgttgac cgattgcctg ccaagctgag ggtaaaaatg aaatacccaa
    31621 gcttgcgccg acaatgatca tcagcaaagt aatgacacgt ttttgcatcg tttttcctcc
    31681 gtttcgacaa tcatttatta gttagcggaa cacacgcttc aacgtttcag ccaaagttgc
    31741 tactccaact atctcgattc cttttggcgc ttcccagtta cctaagttgt ttttaggtag
    31801 gtatactttt gtgaagccga gtttttggac ttctttgact cgttgttcaa tatgactgac
    31861 acgtctgatt tctccagtca gtccaatttc accgatgaaa cattccgttg gctgtgttcc
    31921 tttttcttta tagcttgaag caatactgac agcgatagct aaatcaatcg ctggttcatt
    31981 taattttacc ccacctgcag cttttaagta agcatcttga ttctgaagaa gcaacccagc
    32041 tcttttttcc agcactgcca tgatcagaga tacccgattg aaatcaagac ctgttgttgt
    32101 tcgtttggca tttccgaaca tagtaggtgt gactaatgct tggatctcta ccaaaattgg
    32161 acgtgtccct tccattgcca caacgatagc agagccagtt gcaccgtcta ggcgttcttc
    32221 taagaaaatc tgtgaaggat tagcgacttc ttccaatcca tgctcatgca tttcaaaaat
    32281 cccaatctca ttcgttgagc caaatcggtt ttttactgct cgcaaaatcc gaaaactatg
    32341 atgttgttca ccttcaaaat ataacaccgt atccaccata tgttctaaca ttcttgggcc
    32401 ggcgatcgag ccttctttgg taacatgacc gacgataaaa atggctatcc catttgtttt
    32461 agcggttttg agtagttctg cagtggtttc tcttacttgg ctgacacttc ctgccacact
    32521 tgtgatgtct ggctgcgtca tcgtttggat ggaatcaatg ataacataat caggggagat
    32581 atgttcgatg gcacgactga tttcgttcat atctgtttca gcgtatagat aaaattctgt
    32641 gttgatactt ccgaggcgtt ccgcgcgtaa ttttatctgc tctgcgcttt cttcgccgga
    32701 tacatataag acttttccgc ctatggctgc taattgctga gaaacttgta acagcaaagt
    32761 ggatttcccg atacctggat cgccaccaat caagaccata gaccctggca ccacacctcc
    32821 gcctaacaca cggttcagtt cttctaattt tgttttgatc cgaggttctt ttttagggac
    32881 gacgtctgcg atttttgttg gttttgcttt ttctcctgtc aaacttgtcc gagttctgcg
    32941 gtccgttgta tcttgttcga tttcttcgac catcgtattc cattttccgc aatttgggca
    33001 gcgtcccaag aacttaggcg acacataccc gcaattttgg caaacaaatt gtacttttga
    33061 tttttttgcc attgtaccgc ctccttttat cctaatcatg agacattaaa tcaagcttaa
    33121 gtatctttaa cgttttattt actggaagaa ccaaatccgc cttgacgttg agcagtcgtt
    33181 tgatcttgat ctgcttttaa aaacggcaaa aagatccctt ggccgatacg ctcgcctttt
    33241 ttgatcacta catccttgaa accaaagttg gtgaattgga acatgatatg gccttcattt
    33301 gcctcattat tgtaataatc actgtcaatc acacctactc cgtttgtcaa cactaaaaac
    33361 cgcttcaacg gattgcttga acggttagca agctgcaaaa attcatcttc tcccatgtaa
    33421 gctttgattc cagtaggcac gagggttggt ttcaattgtt tttcattttc tgatacatct
    33481 tttttcaatc catctgcgac tgtttccaac ccctttttcc agcctgcttt ccagatactt
    33541 ggaatcacga cctcttctgc tgcttcaaaa tcatagccag cagcatgatg tgtagcgcgc
    33601 tgcggtagat tgatattttg atctttatat ttagaaataa cttcaaatcc tctttttctc
    33661 accggttttc ctccctaaat aaactactcc tattctaaca tatccgaggc tgtaaaagac
    33721 tttctttaca aattcttcaa gaaattctgc tatcttaaag taaaccatta attcgttctt
    33781 tttccaaacg actgcaagtt gtacaaaaaa actatttttt acatgacttt actcgtcaaa
    33841 acaagtagaa tagaacgaaa ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa
    33901 gaaattaaaa atgcaaaacg aattattgtc aaagtaggaa caagtacatt gatttatccc
    33961 aatggaaata tcaatcttgc ggcaatcgat cagttagctt ttgtcctttc tgatcttaga
    34021 aatcggggaa aggaagtgat cttagtctca tcaggagctg taggcgttgg tatgcataaa
    34081 ttacatttgt cagaacgtcc gactttgatt cctgaacagc aagctgcggc ggctgttggt
    34141 caagccgaac tgatgaatat ctataatcaa agattcagtg tatataatca acagacggca
    34201 cagatcctcg tgacaagaga cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat
    34261 acattggaac agcttttgat tatggacacg atccctatcg tgaacgaaaa cgatactgta
    34321 gcagtggatg aattagatca tctgacaaaa tttggcgata atgatcagct gtcagccatc
    34381 atggcaaaac ttgtcgcggc agaccttttg atcgtccttt ctgatatcga cgggttttat
    34441 tcagataatc cgactacaaa tcccgaggct cagatgtatc gctatatcga taaaatcgat
    34501 gaaaagattc tggcacaagc aggtggtgct ggtagcacat ttggaacagg cggtatgcag
    34561 agtaaattaa aagccgcttc taggatattt gaagcaaaca gcgcaatgat tttagcaaat
    34621 ggaaaaaatc cggcaattat ttttgatatt cttgcaggaa aagaagtagg tactttattt
    34681 aaggaggact tgaaatgact gacttgatgc aattaggaca acaggcaaaa gatagcgcgc
    34741 aacaactagc acttatgcct acaaaccgca aaaatgagct acttgttcaa atggcacaaa
    34801 ccatcaaaaa gaatcaacaa gcgatcattg aagcaaatca taaagactta gaaaaagcag
    34861 tcgaaaacaa tatcagtgaa acgatgcaag accgcttgca gctgacacct gagcgaatca
    34921 atgccatggc tacagagatc gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag
    34981 atgagatgtg gacgaacacc gacggattga gaatcggcaa aaagcgcgtg ccactaggcg
    35041 tgatcggcat catttacgaa tctcgtccaa atgtcacgac agatgcagct agtctagcat
    35101 tcaaatcagg gaatgccgtt atccttcgcg gtggcaaaga agcattcttc tcgaatcaat
    35161 tattagtcca attattgcag caagtactgg tcagtgctgg cgaatctcct tatgccatcc
    35221 agtttgtcga tgatacttct catgaaactg caggacagtt gatgcgattg acagaatact
    35281 tagatgtgct gattcctcga ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa
    35341 cggtacctat cattgaaaca ggtacaggaa ataatcacgt atatatcgat aaagaagcac
    35401 agttatctat ggcagtgaac atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta
    35461 acgcggcaga aacattgctg atccattctg agatcgcacc ttttttcttg ccagctattg
    35521 aaaaagaact ggtagaacac ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc
    35581 tagagacggc tgctttagca gaagacacag attgggatac tgaatatcta gattatatcc
    35641 ttgctgtcaa agtggtcgat tctttggatg aagcaattgc acatatcaat cggcataata
    35701 ctaaacattc agaaacgatc gtgacagata gttatgcggc tagtcaacgt ttcttaaatg
    35761 aagtggacgc ggcggctgtc tatgtcaatg cctccactcg ttttacagac ggatcggtat
    35821 ttggttttgg tgcagagatt ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg
    35881 ggttaaatga attaacttcc acaaaatata tcatttatgg cgatggacaa atccgcgaat
    35941 aatgtttcgt gtgaaacatt attcccgcct tttgcctttt ttctgtaaag gttctatcca
    36001 actagaaagg tgtcaatatg tttgaaattt taatgatttt ttttatttac cttatttctc
    36061 tgaatatcgc tgcttttctg ggagtcggta ttttatccct tttctttcaa ttcaaaaaac
    36121 gaagcatagg gagtcaacgg gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag
    36181 ggctggttac acgcttgcac attagttaca tggttgcatt atgcttatta gcgacaatca
    36241 attactattc ttttttcgat cattcaatcg cttatacgat tacgctactg attgctggga
    36301 tttttcactt atcttataaa tatcagctga ataaaaacca cttgaatcgg actttccgct
    36361 aaaaaatatc cgtacgataa gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt
    36421 ttagaggctg tgacaaagat tttgtcacag cctctttttc catataaacg gcgttcgcct
    36481 accagctgcc tggtaaatct gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt
    36541 cgccatcata ataacgaagc agctcatcca tggacaagtt catcgttttt tctttttctt
    36601 cttccgctga ttcagccagt agctgttccc gatacacctg atacatacca gctatttttt
    36661 gctgcatcgc ttttctagtt tcaccttccg cattgattat tggcaattct ttgatatagc
    36721 cacgataaat caaccgatca tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga
    36781 cttcctgaaa atattcttcc agcatctatt atccccccat tctttttctt aaatgaattt
    36841 tagcttacct actgaaaatt ttccagtttc attattttga gaaaaaaagg gaatgtgaca
    36901 aaaatcgtgt cacatcccct ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc
    36961 ataagtcaca atattcaaca aacatgagaa actgtttttt gaaattgttc cttgtgattc
    37021 agagttaaac gacagtctca caacctcttg gtaaacggcg ttcaatcagc tgaccctcgg
    37081 tattagctca aaaaacggta aaatatgaga agctattttt ccgttttgtt tctctaatac
    37141 ttaggataaa acgctgattt tacaacctct gttaaacggt gttcaatcag ctgtccttcg
    37201 gtattagctc aaaaaacggc aaaatatgag gaactatttt tccgtttgtt tctctaatac
    37261 tcaggacaaa acgctgattt tacaacctcc tgataaacgg tgttcaaaag cttgcatctg
    37321 cggtaataag cccaaccaaa cgaaaaatat gagaagctat ttttgtttgg ctgttcttat
    37381 gacttgatgc aggacagctt tttcacaacc tctgatttct tattcttctt catttgtagc
    37441 aaaataatta cggtgataaa tgatacaaca tacactgata agaacaatgg cacctgcaaa
    37501 ataaaacgca tagctttcac caatatgttc accaatcaca cctgcaataa atggtgctaa
    37561 agctccaccg aaaaagcgga caaaactata gctggacgaa gcaacgtttc gttgcagacc
    37621 tggtatttcc atagcaatcg tcgtcaacag tgtattgata attccttgga aaaatcctgc
    37681 taacacaatg ctgatcggta caaggactgg catagaagtt ccagctccta ataacagcaa
    37741 acaaataatg aataagacaa atgctgctaa aattgtccga taagtcgtaa acttccgctc
    37801 aagagccggt gcaacgaaaa tcgaagcaat agccagaagc acaccccagc caaaaaatac
    37861 aaaaccgact tctaattcag aatagccaat caataaaaat ggcgcatacg caagtaaagt
    37921 aaagaatccg aaattatata acaatgcgat tagtccaact gaacgaagtt tatgattgct
    37981 taacgctttg acaccttccc aaaggcctac ttttctcttt ggtttctcag tttcaggtaa
    38041 aagtaccgct agggctataa aaccgcaaaa catcaaaaat gctaccccaa aaaatggata
    38101 acgccatgaa ccactgccca agaccccacc gactagaggg ccaacagcca ttccgcagcc
    38161 aagtgctgct tcatacatca tgattgcttt ttctgtgtta ccaactaaaa tactgacgat
    38221 cgttgctaaa gcagtagaga caaataaagc attcccgaca ccccagccgg cacgtaaccc
    38281 aatcagcatt ccgatattcc cagataatcc gccaagacca gcgaatacaa cgatgataaa
    38341 caatcctgtc atcaatgttt ttttcaaacc gatccgacta gataagaaac ctgtaaatag
    38401 catcaccaca ccagtgacta acatgtaact agtaaataac agggtcgttt cagctggcgt
    38461 agcgtttaac tgtgcagcaa tcgtttttaa gattgggtct actagaccca ctcccataaa
    38521 agcgatcata caggtagctg ctacaactag cgctgaactt ttcccctttg tttcttcatt
    38581 tgtttgttct tgtatatcta tttgattctc caatatttcc atccctttct ctctattagc
    38641 atcatacatg atttatttta catgtcaata tgcacatgta aaacgtggaa actttactgt
    38701 gatataataa agaaaataag acgagaggta ggatttttat gaatacttta gcctatatat
    38761 tattatgcgt gcttttatcc aaaccacgtt ctgggtatga attgaagcag ctgatcacaa
    38821 ttttttggga agcccatcac agtcagatct atacaacgct tgccaagtta gaccagcagg
    38881 gttatgtgac cgttttggac aaagacgagc actctcaaaa aaagatctac cacttgactg
    38941 atgaaggacg tgctcttgta gaggaatgga tcaaagagga aactcccgct cctacgcaaa
    39001 aagatgaatt tctagcaaaa atctatgctt tttcgacgct cgataaaaca acagctactg
    39061 gactgctatt cactagagaa caacagctga acaaaatcat gcaaaaaaat caaaaaaaat
    39121 tgaatgacct ctcgctagac aagaaacaag aatttggacg ttatgttgtg atccagcgca
    39181 gaattatgct ttgtcagcag gaactccaat ggtgtcagca agtaagagaa caaatgcagc
    39241 agttttttga gtaagggata aacagaacct ttctagaaat atctattgaa gagcaaatta
    39301 tcttcaataa aagagcaata cagttggaaa agaaaaagcg atccgaacga caggccaaaa
    39361 cctatcgttc ggatcactat ttttctagaa ctgcattcaa gagactatga caaaaagcat
    39421 gccaaggcct tttttcaaat aacagtgttc catcattcat tactttgaat tgcttttagc
    39481 acacttcttg aaagcgggcc aacgatgatc aactgcaacg gtaaagcggc aatcacattc
    39541 attttccaag cattcatata agcagagaat aattgatcag gtattccttg ttccatgatc
    39601 acaccgaata aagacataca tgtcaccatt cctaaaacca tcaagcatga aatagttaag
    39661 atcatttgga ccttgctttc tggatttact ggtagtttaa aggcaatttt tttcgccagc
    39721 acaccgatga tgaagacatc caaaatgaaa gccaccacga atccaggcac tagaccaatc
    39781 aacaaacttg ataaatgaag atcttgatgc agccataaat tatacgcgct catccccaag
    39841 accatcaaaa aacacatcat tgttgtaaaa attattcctt cttttttatt tgtaggcaat
    39901 ctgtaccact cctttaaatt tgtcacgaaa atcatcgtag cacatttaaa aatttctcgt
    39961 aagtactttt tttattttct gcccttttat ttcataaact tcatcagccg tacgctcgac
    40021 aaagtaagaa tcatgagaag taaacaaaat cgttcccgga tatatttgca ttagcttctc
    40081 taaagcttcg atcgttgcca tatcaataaa attagtcggt tcatctaaca gcaacacatt
    40141 acttggctta gtaaaaagca aagcaatcgt cagacgggtc gcttctcccc cacttaatgt
    40201 acataacggt ttcgtcaaag tttcctgagc aaaccctaag tgattcagca aactacggac
    40261 aagcgattct gaaaactctg tttgtctcat gacaaaacga atgatggatt cttcagatgt
    40321 catttgataa cccttttgct gatatacttg aaagcttact ttcggagaga gaaggattcc
    40381 ttctccttgt ttgcggatat gttctaataa ggttgtctta cctgaaccat tttcaccgac
    40441 aatcgcgatt tttttaccta aagaaaactg aaaatcacca tttaccagta atgttctccc
    40501 acttctttcc aattggacat tttgtcccat gatgggatag cggctgtgga gttcaagaga
    40561 ttttggtact ggaaaacgga tttgtttcat ctgctgcggc ttggttgttt ctcctatttt
    40621 ttggagtctt ctctctaatg ttttcgcatt cttttggatg gctttttgta cactgtcttt
    40681 ttgtttagag gaagacaacc gatccagtct gatttgttgc tttttctttt tactggacac
    40741 tttttccaac ttttccgctt gttttttctt ttcttggatc gatttttcca atcgtttttt
    40801 ctctttcatg atcgactctg cttctcgtag ctgagtcttt ttctccaatt ccttttgagt
    40861 gagataggca ctataattcc ccgaaaactc tcggatttct ccgtctttta cttcccagat
    40921 tttcgatgct agctcatcta gaaaatagcg atcatgacta acaaaaacca gcgtaccata
    40981 ataataacga agctcttcaa tcagtcgatc aatacttttt ctatctagat gggttgttgg
    41041 ctcgtctaga agcatccctt gttcataaga agaaagaaga cgtatcaact cgatctttcg
    41101 ttcttcccct ccgctccatt tccgctctga agtttcttcc agtcttaact ggaaatgact
    41161 ggctaattcc aaatttaggt cctttgcttc agcgagatag gttaattgag gcaggtagtt
    41221 gaaggtgatc tctgtttgga ttttcccatg atcgggaaaa agttcaccgg ctattagttt
    41281 gagcaaagtc gatttaccga caccattttc tcctatgatc cctatacgat cttgctgata
    41341 gacacgaaga gaatcaatag atagttctag ctggttgcca aagctgactt gtagatttgt
    41401 tatatttact gctaaatttt ccatatgttt tacactccta tttcatgtaa aacaacaatt
    41461 atcgatacta aaaaagagca gaaaaatctg tttgcaaaaa aactgcatca catcttttcc
    41521 tactctgaac gaaataacta tgactaaatc accaaatctg tcatagcttt cacctattct
    41581 actgtcgttc gaaaaaatgg acatactcca tccatgaaat tgttgtttat acatgtcttt
    41641 tgaatttatt tagttgttat tcaaaagttc gaaacgtaat ttcatcgatg cagtcatttt
    41701 tccgacctcc ttttttatta ggttaccaca cacgattcaa aaaaagcaat agctactgaa
    41761 tagtaactga aaacctttta ttcgaacata gtgatctttt ctggtgctaa acgaacagac
    41821 tcgtaacctt cttctaccgc ttttcctatt gataaaataa taactggaac ataacggtct
    41881 ttatccaaac caaatgcctc tgccaactga tctgcttcga atccaccaat tggatttgtt
    41941 tcatagccat gatcacgcgc aactaacatg aattgcatag ccgctaagct agaatcgact
    42001 ttgactacat cgttcatttc ttctcttgaa aaactcttgt aataaggaat gatcgcagct
    42061 aattgttgat ctctgacttc ttttggcatc ttccctgatt cgtaagcttg gttgtagatt
    42121 tcttcgccat attcgtaaca ttgcatatcg ccaaaaatca tgaccattgc agaagaagta
    42181 tcattttgtc tcgtattgaa acggatcaaa ggacgcaaga tttcttttgc ttcctcgctt
    42241 tcagcgacca caaagcgcca tggtttcata ttgacagaag aaggtgcagt cgtcgcttct
    42301 ttgatcattt ccagcatttc ttcgtgtggg attttgtatg tttcatcata tacgcgaacg
    42361 gatcttctac cagtcataat tgttgaaaaa tcattttttt gttccattat tattaacctc
    42421 tttcgtttct gttgttatat tgcaaagttg ggtattcaat ttatctaaaa gtgttagaaa
    42481 ttgtttcatt tctacatcgc tgaaagccgg ggatagcacg gaacctgtat ctttatggtc
    42541 catttcacaa tgcttgattt tcttctgggc tttttctgtt agcgctacat acacttcccg
    42601 gttgttctga ggatttctct gacgcgaaac atagccattt gcttccaata ccttcagatg
    42661 acgagtaact gctccttgat caatctgcaa cttttcttgc aaactgcttt gtagcaatgg
    42721 attttcttct ttcagtctca tcatgatctc gtatctagta agacttatac cgatattttc
    42781 ttcaaagatc tggacgattt tttgatcggc taatttgatt tgatataaaa ggtgactaat
    42841 ctcttctaaa gacataattt cctcctttct aataattgac tcgtcaacga ttgacttgtc
    42901 aataatagaa taaaaaaaga aaaaagtcaa agaatcagct gtgtaataaa aaaaacgctc
    42961 tcaatagaaa agtatagaga aaagaaattt tttgtagaat gaacggaaaa aatgataaag
    43021 aaagcacaac gctaaaacca agattattga ttcttatcaa actatagaag atagctcttc
    43081 tgcagtagat aattttacac cgccaaaaat ttccgaaatc gccttttgca agaatcccgt
    43141 cgaatattag aaattggatc agtatgctta aacagtaata aaaaagttat gacaagatgt
    43201 tgtcacaacc ttttttgagt aaacggtgtt caaaaacttg catctgcggt aataagttca
    43261 accaaacaaa aaacatgaaa atctgttttt gtttggctgt tcttactact tgatgcaggg
    43321 cagctttttc actacctctt tttaataacc ataaaatcct attccttcat atctccagcc
    43381 catcggtgtt agccaatctc tttccttagc actcaaggta tagtgatggg taccagtttt
    43441 ttcatttgga ttaaatagtc gataaattgg cttggaacca ccagaataaa aacttagacc
    43501 ttcataacgc caaccgattt ttgttaaaga gttgatctca gattgtgcca ttgtgtaatg
    43561 atggtctcca ctgtaaggat tgtataaacg gtagacaggt tgtccgctgt ttggtgcttg
    43621 ccaagcaatc ccttcatatt cccagcctac agttggcaga taattttttt ctccggcatt
    43681 caatgtatat aaatgttctc ctgtatgacg gttatacaga cgatacatcg gagaagttga
    43741 agttggtgct gtatcatact gtgtcagatt ataggtttcg attacattgt tcaatgtaga
    43801 accataatta ggcgcagtgg cataacgacc tgttagccaa gccgtagcat ctttgtaaga
    43861 gttcgtattg cttttccatg caccggaata gtagtaaacg cctggctgaa aagaagtcgt
    43921 cttcaatacc gttacgttat cttgcaatga ttctttgtac gaaggatatt ttctaaaagc
    43981 ggcattcacc gtaatccatt gcccattcac atattccgaa gtaggcatcg taacagattg
    44041 gccattatag cttcctttaa tcccaaatag attgtaatta ggggcagaag ccaaagtact
    44101 gttcccccag ccactttcaa cgatggcttg agcaatcatg actgatgcat ataagtcatt
    44161 ggcacttgcc aaactttgtg cagttgaggc aatactatca atgaacgctt gttgagaatt
    44221 agcagatgag cgagcataaa aagcatagcc agtatagttt tcgaattcag acaaatctgc
    44281 ttgatgggta tgtgtcaatg tttgcccatc tgtcaattgg ttcgtgattt cttctgcatt
    44341 ctctggattg ttctgagctt ctgctgatgt actgtcttcg gtttgtgttt gttctgttgt
    44401 ttcagttgtt ggttcttcgg ttgaaattgt attttctgag acagtagctg actgcaaagt
    44461 actttctgta tcgttttcaa ttcctgtttc tgaagaactc gatgtctgag ttgcgacagt
    44521 ttctgtcgat tcttcagcta gcactgttgt gttggcaact gctagatttc ctaaaagaat
    44581 aacgctaaat aataaattct ttgctttcat cttttttctc ctttgaatta tgaaactttt
    44641 cctaaataac agtgtaacta aaaaagtaaa agcaagtcaa tgtccatatt taaataacat
    44701 ttgtttcttt ttaataaatt tgctttttct gcataaaaag acgtaaatga agaatattct
    44761 tctccattca cgccttaaat tgatggtcgt ttgaataact atttaacaag taattctctc
    44821 tggatattat ccgttatgga ttatacttcc tgtgtcgtcg gacggataat catgttgctg
    44881 acagacatcc ggtctggcgt ttctatcgca aatgctacag cagaagctat atcttcagat
    44941 gttaatcccc attctttttg cgcttcatga agttcaagag cagccttttt gtcgctgatg
    45001 gtttgatata attcagtttg aacagctcct ggagagatga tcgtagattt gatgttattt
    45061 tgccgttgct cttgacgtaa tccttccatg attgcacgga cagcaaattt tgttccgcaa
    45121 taaacggcgg aatcaggata aacaacatgt cccgccacag aatcagttga aatgatatgc
    45181 ccagattttt gtttttccat gattggaagt acggcggaaa ttccatttaa cacacccatg
    45241 atgttgatat caagcatatt ttgccattca tcacggtgac cttcaactaa tggagcggtt
    45301 ggcatgattc ctgcattatt gtacaataca tcgattcgac cgaacttttc catcgctaaa
    45361 tcgataactg cttggacttg tgcaaaatct cttacatctg ctgtttgaat atatagctca
    45421 gcttctggta aagattcttt tattgctttt aggcgatctt ctcggcgtgc agctataact
    45481 agtttagccc ctttttctgc taatagcttc gttgttgctt caccgattcc gcttgaagcg
    45541 cccatgatga caatcacttt ttctgataaa tcattcattc tattctcctc ctgttttgaa
    45601 aaatctcttg cttatactca ctatctctta tttcatctta ctgttcaaat aatccgttcg
    45661 acaggtttga cgattttggc agggattcct gcaacgatgg tattgtctgg gacatctttc
    45721 gtaacagttg cattcgctgc aacaatggca ttctcgccaa tcgttacgcc tggcagaata
    45781 gttgctcctg ctccgatcca agcatttttc ttgatgtgga ttggctttac tgacaagcct
    45841 cttcgttctt ttggatcggt tagatggttc accgtgatga ggttgacacg aggaccaatc
    45901 aatactgaat cttctaaaca gatgccacct aagtcaacga acatcacttg acgattgata
    45961 aagacatttt tccctatact aatatgtttg ccgaaatctg tataaaaagg cagcagaaca
    46021 gtcaccgtat catctacttt gtcactaatg atattttcta gccgtttgcg gatatctgct
    46081 ggttcatggt acccagtatt cagcgctgct aaaggctctt cgttttccgc ttggatctga
    46141 tggatcactt caaagagcgg atccgttact cgaatctctt tattgacgat ttgtttttcg
    46201 atgaggcttg tcattttgct ccctcctttt atccttactt tataacggac ggcttatgat
    46261 gtctaatact tataaaacat acttaactat tccttttaac tatacttagt ggtatgcttt
    46321 tttaaaaaca ggagggaaaa aatggatatt cgtatactga cgtatttttt agcagtagct
    46381 agagaaaaaa atatcagccg agcagcaaaa tctctgcata tcacgcaacc tactctctca
    46441 aaacaactga aagatttaga agaagaactt ggtgtgacac ttttcactcg aggctcccga
    46501 gagatacagt tgacggattc tggtcgatat ctttattcaa aaggaaaaga aatcttgtcg
    46561 ttggtagaaa aaacggcgaa caatttaaca aatgacgcaa tcatctctgg agaaatctac
    46621 attggcggag gcgaaactaa agcaatctct ttcatttctg atagccttca ttcgttgatc
    46681 aaggcgcatc ctgatatcca gtttcattta tatagcggga atgcagatga tatcatagac
    46741 aaactggata gcggattact tgattttgga ctcgtaatcg aaccgacaaa caaacaaaaa
    46801 taccagtcat ttcgactgcc agcccaagat cgttggggac ttttgataca tcggaatcat
    46861 cctttagcaa agcaaacagt catccatccg caggaactga aaactgttcc tttgatcatt
    46921 tcccggcaaa cgtcagtgga cagtcaacta gctgaatggc taggtttcag catagatcag
    46981 ttatcgatcg tcggaacata taacttattg tacaatgctt ctttgatggt cgataacggg
    47041 acttttggtg cattagctct agatgggatc atcaatactt atgggacgga aaaagtattc
    47101 atcccactcg atccgccatt acaagcttca ctgaatctca tttggaaaaa agaccagcct
    47161 ctttctcctg ctgctcgtaa atttttagat gtcctaacgg agaaatacag ttaagtagag
    47221 tttttttcct tcgctttcag ctttttaaca acgaataagt taagcaaaag atccaatgat
    47281 taaataacat aagtttctta atttgttcct tccttttatt tctgataatt ccagtaaatt
    47341 actataatta taaaaaaaga attgacaaaa cataactgtc tatataaaat tgattacgtt
    47401 aacaataatt cgtttcatgt gactagatca tactaggcat gaaaaatctc tgaggaacat
    47461 ggtttcccta ggaggttttt cgtgtctatt tttgtttggc cgcaatcaac tggtctagca
    47521 aacgtgaaaa ccaaatcttc aaaaagggtg cgcgcatgaa aatcaaaaag atctttaatc
    47581 aaaatgcagt attggtagat gacggtggac aggaaaaagt agctattgga aaagggattg
    47641 gatttgacag aaaaagaaat gatttgattt ttgatcgtga tgtcgaacgg atatttgtca
    47701 tggaaccaga aggtcaaatc aagttgcaaa atttacttaa tcagattgat gaacgctttt
    47761 tatttgcagc agaaacgatc attgatcatg cggaaactgt tttgatggaa aagttgaatg
    47821 aacatgtatt gatcgctttg accgaccaca ttgctttttc tgcggagaac attaataacg
    47881 gtatcgtcat ccgcaacaaa cttttaagag aaatcgaagt gctttacagt gatgaattca
    47941 gtattgctca atgggcagta gagtatctga caaaagagct tgggattcca tatacttatg
    48001 acgaagcagg atatatcgca atccatattc acagcggacg aagcggtcgg aacaataacc
    48061 atcgcagtat ccgtgaagtg acgattgtat ctgacatcat ccatttagtg gaatcagaat
    48121 tggaaacaga tatccattca gaaccatttt cactgaatta ttcaagactg gtgaatcatt
    48181 tacgactgct tctacaacga acccatgcgc aacaatatgc tgttttagac acggaaatcg
    48241 tagaaatggt caaacgaaaa tacccagaaa gctataagat ttctaaaaaa atccgtgtgt
    48301 tgctgaccaa agaataccag ctcgcgatca cgaaagaaga actgggttac ttggccatcc
    48361 atatcgagcg tttaagaagc gcaatcgtac aaacaaatgt taacaatcat gaggaggaaa
    48421 aaaattgaaa gcatatctac aacgaatggg acgttccctt caacttccag ttgcggtctt
    48481 acctgctgct gctttactag tagggatcgg aaactggtgg gcatcttata gtaacgacat
    48541 tgtcgctcat tttttacaag ctggcggtaa cgcagtttta ggtcaattac ctttgctgtt
    48601 tgccgttggg ttagcactag ggatgtcagt ggacaaatca ggtgctgctg ccttggcagg
    48661 tttggtcgca tttgaagttc cagtaaatgt tttaaaaact gattcagtag ctactttatt
    48721 gaatatcaaa ccagaatcag ttgatccatc ttttgctcag atcagtaacg tatttattgg
    48781 tattattgcc ggattgattg cggcagctct ttataatcgt ttccacgaag caaaattacc
    48841 gatggcttta tctttcttta gcggcaagcg tctagtgcca atcttggctg cctttgtcat
    48901 gttgctgatc agtgcagtgc tactgctcgt atggcctccg gtttactctg ctttagtttc
    48961 ttttgctaaa ttcattttga gtttaggctg gggtggtgca ggtctttatg gcttcttcaa
    49021 ccgtttactg atccctacag gattgcatca agcaatgaac tccgtgttct ggtttgacgt
    49081 agcaggaatc aatgatattg gtaaattttt ggcttctgaa ggaacaaaag gcgtaacagg
    49141 aatgtatcaa gctggatttt tcccaatcat gatgttcggg cttccagcag gagcatatgc
    49201 tatttacaga aatgcacgtc cagaaaacaa agcaaaaaca gcttccttga tgttagcagc
    49261 agcttttgct tcattcttta ctggtgtaac agaaccactt gaattctcat ttatgttcgt
    49321 tgcttggcca ttatatgtct tgcatgcaat tttcactggg atttctttag cagtgagtgc
    49381 attcttccat tggacagcag gatttgcctt tagtgccgga tttgtcgatt acttcctatc
    49441 tttgaaaaat ccgattgcga atcagccatt gatgttgatc gtccaaggat tagtaacagc
    49501 agtgatttac tactttggct ttaactttgc tatcaaaaaa ttccatctga tgactcctgg
    49561 ccgcgaggaa gcagatcttt cagatgacga tactgcaacg actaattcag acaataaata
    49621 tgcggcacaa gcaagcaaaa tctacgctgc attaggcgga gccgacaatg taacttcgat
    49681 cgataactgt actacacgcc ttcgtttgca agtcaaagat acaggcctga tcgatcaaaa
    49741 taaaatcaaa gccactggcg tacctggtat gaagatcatc gacggaaaaa atgcgcaagt
    49801 catcgtaggt acagaagtac aattcgttgc agatgagatg gcaaaactac atggtggtgc
    49861 tgcaacacga cctgcacaaa caaacaccgt ggttaaaaca gaaacatttg ccggtggaac
    49921 gatcgaacaa gatatttacg ctatcgcaaa tgggaaactg attccaatca ctgaagtttc
    49981 agatgatgta ttcgcggaaa aaatgatggg tgacggctat gctgtattac cagaaaatgg
    50041 agaaatcttc tctccaatcg ctggtacgat cacaaacatt ttcccaacga aacatgctgt
    50101 cggaatccaa acagatgctg gtatcgaagt cttgcttcat atgggcatca acactgttga
    50161 cttaaaaggc gaaccattca ctttatatgt aaaagaaggt caaaaagtcg caagaggtca
    50221 attgattgct ttagttgatc ttgccgctat tcaatctgca ggcaaaaaca cggatatggt
    50281 cgttgtattc acaaatggcg acaaagtcca aagcttagaa atcgaacccg cacgtgatgt
    50341 aaaagcaaat gataaaatcg gctctgtttc caacaaagcc tgagccatcg tcttccccag
    50401 acttttttat cgataaacaa acaggagctg agacaaaaat cttgtctcag ctcctttttc
    50461 cgaataaaaa cggcgttctc ctgccaactc cgcggtaata agtccagcca aacgtaacat
    50521 atgaagagct attttttatt tgactcttct tattacttga tgcagaacag cttttttaca
    50581 acctctgata aacggtgttc aaaaaccagt ttatcggtat gaagtcaaat ttatgcaaaa
    50641 atgtggaaag ccattttcac aaaatttttc ttcatactca aaactaatcg gctttttcac
    50701 aacctcttta tacattattc ctgatccaat atttctttta atgctgcttc aagagaagtt
    50761 aatggttttc ccaatacttt ttctaaatca tcagaggaaa tagctaactg atccttttta
    50821 atatcatgtt ggatcgctaa aaacatgtca gctgcttctt gagggaatcc ggcttctttt
    50881 agattttcga caaacgctgc atcacttgct tcaataattt ctaacttttt acctgtcgca
    50941 cgctctaatg ccttggctaa ttcttcatag tcagttagat tgccggataa ttctaagatt
    51001 tctggagagt cactttctac tagtactttt gctgcagctt ctgcatattc acgtttcaat
    51061 gcccaacctg tttttccatt tcctgcagca taaacgaatt gaccagtttt taaagcctgc
    51121 ccaatgatag gtaattcatt ctctacatac caattattcc gtaaaaatgt atgggaaata
    51181 cctgaatcct taatcatttt ttcagtgaat tggtgatctg gcgctaatac actgatcgag
    51241 tgatcggcat ctgcaaaact tgtataagcg atataagata ccccagctgc ttgtgctgcc
    51301 ttcactacat tcttatgttc ggcttgacga tttcctggaa cgccagagac aaaaagcaat
    51361 cgatctattc ctttcaacgc ttctttcatt gagtctaaat catcataatc accaatacgt
    51421 atattaaatc cagcttcttt cagtgcttct cctttttctt cactacgtac tagtacatag
    51481 atttcatttt gtggaaccat cttttttaag aattccagcg cataaccacc aaaacctcca
    51541 gttgctcctg ttactaaata atgcatattt gccactccct attcttttta tttgttaaga
    51601 tttacagctg tacatttata aattacacct ttatcataaa gagtgtggta agataagtca
    51661 agcaaaaaaa atgaaaggat gacaactgat gaagtattct ctgcaattta gtgatgcaat
    51721 ccatgtactt gcctatattg aaatgtttca agatacccga tcactttcta gtgagatgat
    51781 tgccagtagt atcgaaacaa atgcagcaaa tgtacgtaaa atcatgagtc agctcaaaaa
    51841 atccggtttg atctttacaa aaaccggaaa accgcagcct tcccttgcca aaagtccaga
    51901 tcagatttct ttactagatg tctatcgcag catcgaaggt aatacacagc ttatccaagt
    51961 cgatccaaaa acaaatccaa attgcgtcgt tggtgcgaat atccaagaag ctttagaaga
    52021 aagctacgct cggctgcaga aaaaggcaga agaagaaatg gctaagatca cacttgatag
    52081 tctgatacat aaaatagccg ttttggaaaa agaaaaaaga ccagaaaaca caggcctcgt
    52141 agagagattt ttataattct ctctactgtg cctgcatttt tctgatcgga atcgtctaca
    52201 taaattcttt tattctccgg gggacaaaag ccttgtcatg cccctttttc ctctctaatg
    52261 ctcaggtcaa agcgctgaag tcatgacgtc ttgataaacg gtgttcaagt agctgaccct
    52321 cggcattagt tctgaaaaat gcaaaatatg gaaagctatt tcccattttt cctctctaat
    52381 gctcaggtca aagcgctact ttcacgacct ctatattatc atggtttatt gactaccggt
    52441 atccagattt ctcccatata tttcccgttg gtaactccca tttcgactac agcatttgga
    52501 cccccaacat aggcgtaatc ttctacttct cttaaaacat gcccaaaggc cgtattcgtc
    52561 aaatcatttc ttaattcttc aggcgattct gctaaagcga ttacaacaag atacgttcct
    52621 tttgggaatg ggatgattcg ggtagtgttt ggaacatcct gactcgtttg aacaccgaca
    52681 tagtacatca ttttcccgtt atagggttcg ttgactgtaa agaaataatg attttcagca
    52741 gcttgtttca atgcatctat tgttccatta ccgataactt tttgctcaaa tgcttgtttc
    52801 tctgcagcca aaccgacaaa atccgtattg ctactcttca attccacacc aatacccgtc
    52861 accgtaaaat ctggtttttc ttcgatccta tactttgcca tttctcccac cctttctatt
    52921 atattaagtt catcttacat aaaattaaag ggaaatgaca cgattacgct cttttttcta
    52981 gggatatttt tattttttaa ctattttttt gctttcactg caatccaaat ctcactgtaa
    53041 acattactga aatcctctcc ccattttgta aaagagatct cgggagcttc gactaactca
    53101 taatctgaag aaggaagcca ttctgcatag attttccccc aagtatcttg taaagtttgg
    53161 ggaaatggcc ctttattagg aaaaatggcc caagtgtgtt cttctatagc aagcatttct
    53221 aaatcagcgt acggattttc ttttgtcgta gcaaagccaa tcatgtgcat caaactgccc
    53281 ttttcttcca agcgggctcc atcaaatcca taagaaacgt tgattacttg atttggatat
    53341 aaatctccta acttatgcat ctcttccctt tgagtctccg tgatcgtctg cgctaacttt
    53401 tgtatttctt gattgactcc ttcaaatttg acaggaactt ttttcgccac acctgccaca
    53461 taaaactgtt ctttcttttc gatacgaaat tccatcgatt ttcctcctct gacatcaata
    53521 aaaaatgtca agcgtggaaa agatttttgt atgccgtatc tgctgatttc tgaaggcaga
    53581 tatcctgacc aatcacgaaa agctcttgaa aaaccttcga ctgtttcata tccatatcta
    53641 aacgccgttt ctgtcactct tgatccatct aggagatcgc gattagccaa agccaatcta
    53701 cggtttttga tatagtccat tagcgacatc cctgcaataa acgtaaagat gcgttttaat
    53761 tgatattcag agattcctgt attttcggct attattttat aggaaagtcc ttctgtcaaa
    53821 tgttcttcga tgtaatcgat caattggttc agatctttaa gcatatttat cttcctcctt
    53881 gcttgccttt ttatcatatt atcaaagaaa gtcaattact tgatgaatca ggaaccaatt
    53941 tagtcagatg tagaaaatgt tgtatggatc taaagaaaat tctcaagcag cgtttcgtaa
    54001 cggataattg gtattatctg cctatctatg ttttaccttt agaaaaataa attttgggga
    54061 agacacattc taagtaaaca aagcggtaaa aatatctttt attcccttag ttaatccgct
    54121 tactacctac tgtacaaagc aaattgttgt tcaaactgct gatcagaacg ctgcttggat
    54181 ttttctttgc gatacatcat acctctttta tcaattggaa caattattta tttctaacaa
    54241 aatcacttca tttttgtcag ataaataaaa
//
LOCUS       DACGDM010000011        51850 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.011, whole genome shotgun sequence.
ACCESSION   DACGDM010000011 DACGDM010000000
VERSION     DACGDM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.011"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            188..391
                     /locus_tag="IXR05_000716"
     CDS             188..391
                     /locus_tag="IXR05_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259259.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            602..1186
                     /locus_tag="IXR05_000717"
     CDS             602..1186
                     /locus_tag="IXR05_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4259260.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            1557..2882
                     /locus_tag="IXR05_000718"
     CDS             1557..2882
                     /locus_tag="IXR05_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4259261.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
     gene            2875..3225
                     /locus_tag="IXR05_000719"
     CDS             2875..3225
                     /locus_tag="IXR05_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259262.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            3222..3401
                     /locus_tag="IXR05_000720"
     CDS             3222..3401
                     /locus_tag="IXR05_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259263.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            3537..3827
                     /locus_tag="IXR05_000721"
     CDS             3537..3827
                     /locus_tag="IXR05_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAQ4259264.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            4195..4983
                     /locus_tag="IXR05_000722"
     CDS             4195..4983
                     /locus_tag="IXR05_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4259265.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTTAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            4970..5296
                     /locus_tag="IXR05_000723"
     CDS             4970..5296
                     /locus_tag="IXR05_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259266.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            5645..6685
                     /locus_tag="IXR05_000724"
     CDS             5645..6685
                     /locus_tag="IXR05_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAQ4259267.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDSTVIAKIANTAKPRKINDST
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMQEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKKKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            7521..7853
                     /locus_tag="IXR05_000725"
     CDS             7521..7853
                     /locus_tag="IXR05_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAQ4259268.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            8444..8773
                     /locus_tag="IXR05_000726"
     CDS             8444..8773
                     /locus_tag="IXR05_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259269.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            8760..9101
                     /locus_tag="IXR05_000727"
     CDS             8760..9101
                     /locus_tag="IXR05_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAQ4259270.1"
                     /translation="MKNYDPNSRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQKLTDNPIGFGLLPEDDQGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            9215..9454
                     /locus_tag="IXR05_000728"
     CDS             9215..9454
                     /locus_tag="IXR05_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259271.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            9521..9760
                     /locus_tag="IXR05_000729"
     CDS             9521..9760
                     /locus_tag="IXR05_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259272.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKKSSNCQLLLEVS"
     gene            9846..10517
                     /locus_tag="IXR05_000730"
     CDS             9846..10517
                     /locus_tag="IXR05_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAQ4259273.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGKVFKQNIEKKMPVD
                     QINEHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQAFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            10570..12546
                     /locus_tag="IXR05_000731"
     CDS             10570..12546
                     /locus_tag="IXR05_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4259274.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGAAQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPTGYQKLTEDIAFKVNKNSFKEENRITVKNNQKAAI
                     PLTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            12559..13215
                     /locus_tag="IXR05_000732"
     CDS             12559..13215
                     /locus_tag="IXR05_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4259275.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPAVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSIPLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKK
                     "
     gene            13311..14138
                     /locus_tag="IXR05_000733"
     CDS             13311..14138
                     /locus_tag="IXR05_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259276.1"
                     /translation="MNKRKWLFVCVAALFATAAYSQISFADSSTTPTTSQTTDSSTTA
                     TSDTDSSKNTAEETADSSTSSTESAESTSESSSETSEKLQEVEDTQVIKQNIHIQKII
                     SSNRINNQGRQVTQQEGVNGAKFIVYDITNILEEMTQDDNEKNQSVEIIESKLKDRAK
                     KLSYDQLKKVTEGETQTIDDQEGVIDFSIEVPANKKQAYYIVNESSPENISNSEDIVL
                     LTPVSDEKGEFLTDVWLYPKSKKSEPKEEIKKVVSTGVKKNFFDNCWDFFTHLFFND"
     gene            14148..14396
                     /locus_tag="IXR05_000734"
     CDS             14148..14396
                     /locus_tag="IXR05_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259277.1"
                     /translation="MKIIKMLVFNLSFLAATILCCGLVFSQLSIYPRYQRLFVHFLNI
                     QHASMPLEVINKLLINPIFMASLFLLAGLVTWVLGKKE"
     gene            14427..16538
                     /locus_tag="IXR05_000735"
     CDS             14427..16538
                     /locus_tag="IXR05_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4259278.1"
                     /translation="MEGIMENKIHCTTGRVFTLVLFLFLLLFARGTAVQALEKVDPSQ
                     IKENNNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAH
                     YQKVGTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQ
                     SINVMNVKLDFKYAGSKTKVALSEPQPEINSKMRSMRAAGIELNDTFLSIYSLNGQYQ
                     QRVSWYNDNNESVGERNIDMREFVGYEKMDRLPYFVTTDTACAEYKAPALSTNNLTSK
                     VVGGRAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTAL
                     LWTPQPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKS
                     FKITDTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSF
                     LANAANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNKVENYFSLKPN
                     KKVEQDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIALDHYKQFSIQD
                     PVEARLTYKEGSARVIDMSTGKDITSEGILTYDSHSRTLKWEASADFLNNNLLDGREI
                     QLIFTAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQVIVPKTGSNHLVLT
                     VIGSILFLTLASLGYVVLKLK"
     gene            complement(16576..18633)
                     /locus_tag="IXR05_000736"
     CDS             complement(16576..18633)
                     /locus_tag="IXR05_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HAQ4259279.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYMVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVDILKEQIINVTHGESVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFSTPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(18747..18959)
                     /locus_tag="IXR05_000737"
     CDS             complement(18747..18959)
                     /locus_tag="IXR05_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259280.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            19146..19613
                     /locus_tag="IXR05_000738"
     CDS             19146..19613
                     /locus_tag="IXR05_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259281.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            19610..19852
                     /locus_tag="IXR05_000739"
     CDS             19610..19852
                     /locus_tag="IXR05_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259282.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            19870..20172
                     /locus_tag="IXR05_000740"
     CDS             19870..20172
                     /locus_tag="IXR05_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259283.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            20243..22297
                     /locus_tag="IXR05_000741"
     CDS             20243..22297
                     /locus_tag="IXR05_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259284.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            22297..24129
                     /locus_tag="IXR05_000742"
     CDS             22297..24129
                     /locus_tag="IXR05_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAQ4259285.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNSVTCLA"
     gene            24824..26740
                     /gene="ltrA"
                     /locus_tag="IXR05_000743"
     CDS             24824..26740
                     /gene="ltrA"
                     /locus_tag="IXR05_000743"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAQ4259286.1"
                     /translation="MERDKTMTNTKGISLKNKQLRHAEYYDMTETFDELHAMSVAKSN
                     FKNLMKFIIDDNNIFLAYRNIKKNKGSATAGYDGVTIKDIEKLACGDFLTIIKRRFKD
                     YRPRKVKRVEIPKPNGKLRPLGIPSIWDRIVQQCILQILEPICEAKFNKHSYGFRPNC
                     STENAIADCLARINQSKMNYVVDIDIKGFFDEVNHTKLMRQIWTMGIRDKQLLVIIRK
                     MLKAPIVMRNGNVVFPTKGTPQGGILSPLLANICLNEFDWWIANQWEERTVKELKHHY
                     RKNGAWDKGNIYSKLRSHTSLKEMYLVRYADDFKIFCRTGEEAQRAFYATQKWLRERL
                     KLPISMEKSKVTNLNKAESEFLGFSIRLHKKGKKKVAFTYVCRKAEENIKNKLKQQIK
                     KIQYAGAKKNRHRAIGDYNMMVIGIHNYYRIASHCSVNFTEIYRSVRTVIEARLKARG
                     MTKNGIYGQDHEGYRPYLKSKQMRYIEGFPILPIGYIKKRTPLNKRRNLNKYTKEGRK
                     LIHQEQQAIESWKIKYLVKGFSNNKKYTVEFSDNKISKFISQKGKCAITGNELLMEEI
                     ECHHINPYHLSKDDSYKNLVIISREIHRLIHATSEETILKLLRLLKLNHYQIRKLNTY
                     RKKAANFPISIKMN"
     gene            26857..27657
                     /locus_tag="IXR05_000744"
                     /pseudo
     CDS             26857..27657
                     /locus_tag="IXR05_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            27654..30185
                     /locus_tag="IXR05_000745"
     CDS             27654..30185
                     /locus_tag="IXR05_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259287.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            30235..30567
                     /locus_tag="IXR05_000746"
     CDS             30235..30567
                     /locus_tag="IXR05_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259288.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            30568..31161
                     /locus_tag="IXR05_000747"
     CDS             30568..31161
                     /locus_tag="IXR05_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259289.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            31324..33018
                     /locus_tag="IXR05_000748"
     CDS             31324..33018
                     /locus_tag="IXR05_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4259290.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKCFLAMIDECHNGATCSAVKSCGLQVV"
     gene            33706..35583
                     /gene="ltrA"
                     /locus_tag="IXR05_000749"
     CDS             33706..35583
                     /gene="ltrA"
                     /locus_tag="IXR05_000749"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAQ4259291.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            35714..36091
                     /locus_tag="IXR05_000750"
                     /pseudo
     CDS             35714..36091
                     /locus_tag="IXR05_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            36091..37296
                     /locus_tag="IXR05_000751"
     CDS             36091..37296
                     /locus_tag="IXR05_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4259292.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPSLNSSKK"
     gene            37312..37956
                     /locus_tag="IXR05_000752"
     CDS             37312..37956
                     /locus_tag="IXR05_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259293.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            37967..38773
                     /locus_tag="IXR05_000753"
     CDS             37967..38773
                     /locus_tag="IXR05_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259294.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            38795..39025
                     /locus_tag="IXR05_000754"
     CDS             38795..39025
                     /locus_tag="IXR05_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259295.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            39571..39846
                     /locus_tag="IXR05_000755"
     CDS             39571..39846
                     /locus_tag="IXR05_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259296.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            39888..40310
                     /locus_tag="IXR05_000756"
     CDS             39888..40310
                     /locus_tag="IXR05_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259297.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            40329..41921
                     /locus_tag="IXR05_000757"
     CDS             40329..41921
                     /locus_tag="IXR05_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259298.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            41933..42268
                     /locus_tag="IXR05_000758"
     CDS             41933..42268
                     /locus_tag="IXR05_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259299.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            42415..42609
                     /locus_tag="IXR05_000759"
     CDS             42415..42609
                     /locus_tag="IXR05_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259300.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            42641..45013
                     /locus_tag="IXR05_000760"
     CDS             42641..45013
                     /locus_tag="IXR05_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259301.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     TPTDSVKEKETDHFYRVEFNENDPAKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELARLCEQSPEKEQEQTVKNEPISKV
                     QNEIKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGQTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     ATWTKNSQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVLEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            45074..46534
                     /locus_tag="IXR05_000761"
     CDS             45074..46534
                     /locus_tag="IXR05_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAQ4259302.1"
                     /translation="MTEKKMSLIDRCKQMDIVDFARNNGLAVANKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPDWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPREYKVI
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEVISLKD
                     ICREVAKELKDCERSNGTYDFDRFYQGKGDINSQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIHQQEIRKQKRAMLFQQGRQQERE"
     gene            46545..48749
                     /gene="topB"
                     /locus_tag="IXR05_000762"
     CDS             46545..48749
                     /gene="topB"
                     /locus_tag="IXR05_000762"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4259303.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVTAQNGIFDAKLDPNETQATQEAFEAYLKEKGVQVGKQPGTILEVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EHAYLLDHLDEYKHFLKAESFPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYEK
                     LTPLQQAIYDQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGETVTVDLQIFEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLTKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQATDFGATLQEVKV
                     ASEKQEAARHLGSCPKCQEKEVILYQKVATCTSEACDFKLWVTIAKKKLTATQLKEII
                     QNGRTSQPVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTTYKRKVRRKTS"
     gene            48995..49588
                     /locus_tag="IXR05_000763"
     CDS             48995..49588
                     /locus_tag="IXR05_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4259304.1"
                     /translation="MKDKVKCIFEKYNGNLSLKDARNEGLSPMTLDRLAEKDKIEKIA
                     SGFYTLKDSFVDELYLAQSIYTRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     NLDQYAIQPHYTNKENFELGITEAESFYGNKIFVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMNILKSPKEMTLYMLPLY"
     gene            49604..50503
                     /locus_tag="IXR05_000764"
     CDS             49604..50503
                     /locus_tag="IXR05_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAQ4259305.1"
                     /translation="MTPTQFKAKTRNVAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTAAPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAFLENARVPFKLDITSGDSIIPAALIYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGIDNSRMKDFYDLYMIPKLERIDEINLYKSVQGTFKE
                     RNNQSVFKNLYNQEMPQLMKNEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEEVERKQNFKRSQQMNQEMER"
     gene            50506..50991
                     /gene="ssb"
                     /locus_tag="IXR05_000765"
     CDS             50506..50991
                     /gene="ssb"
                     /locus_tag="IXR05_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4259306.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVTTFTLAVNRNFTNQSGNR
                     EADFINCVIWRKPAETIATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            51357..51617
                     /locus_tag="IXR05_000766"
     CDS             51357..51617
                     /locus_tag="IXR05_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259307.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
BASE COUNT        19132 a         8101 c        10454 g        14163 t
ORIGIN      
        1 agtgacagga acgatgattt ttgataaagt tggttggcct tctagacctc ctcaatcacg
       61 gaattggaaa gaaaaaagaa atggttattg gtactatgga aaattgtatt tacaaagtta
      121 taaatcagct ggaaacaatt ggattgcgac ttattcagga accttaacta gaaagtaggg
      181 attttttatg ccagaatttg tgaacacacc aaatttttat caagatagcg atattctaag
      241 taaaattaat ttaccgaaag aagaatcagc tttacaagtt cagcgaactt tacaggagac
      301 acaaaaaatt caaaaatcaa tttctaatct agaagattct gaagaaaaaa gaaaaaaaag
      361 agaccaaaaa acatatcaaa aagaaaaata atgattttaa aaaaagagtg tctagtcgac
      421 attctttttt tctaattgaa agtgttcata aaatcaccca tttctggaca cttccttttt
      481 ttgctttatt tttcaaaaaa acaattcatt tcatgttcat aaacccataa caatatctat
      541 gttcagttaa actatatgga taaagttatg ttacaataaa attaatgaag gagtgatttt
      601 tttgaaaata ggatacgccc gggtatctac tggtttacaa aatttggatt tacaagaaga
      661 cagcctaaat aaatttggtt gtgaaaaaat ttttactgat catatgagtg gggcaaaaag
      721 taatcgacca ggattagaaa tggccattga ttttgttcgc tctggcgata cacttgtcgt
      781 ttggcgctta gatcgtttag gtagaaatat ggaagatttg atttcaatcg tcaatcgact
      841 gaatgagcgt ggtgtgagtt ttcatagtat tcaagaaaat attacgatgg acaaatcaag
      901 ttctacagga cagctcatgt ttcatttgtt tgcggcattt gcagaatttg agcgtaattt
      961 gatcctggaa cgatccgcag caggacgagc agctgctcgt gcaagaggac ggtttggtgg
     1021 tcgtcctgaa aaattgtctg aacaagattt ggaattactg aagactttag tggatagcgg
     1081 tacacctatt aagactattg cggaacggtg gaacgtctca agaaccacca tttatcgtta
     1141 tttggcaaaa atggaggaga aaaatggaaa gacaaattct cattagtttt tgtcatttaa
     1201 tgctgaaaat ttttgccatt tatctagaaa agtgacaata gtatgagaat tttttgtaag
     1261 tgtctactga taacttatta tcaaatgttg taaggatttt attcatttgt taatattaaa
     1321 gaacggaact ccaaaaaagt ccgtactcta atttgcagtc tctcactctt ttagagtgag
     1381 agtttttatt agattttcaa attaattagt aaagtgatag aataaattga tcatacaaat
     1441 cataagaaga agcagggtga tagcatacct atgcttcttt ttttatgtat ttagctattt
     1501 cttctttaca acatcgaaca tatgtttgta taatgtggaa gaatggagtg ttatttatga
     1561 tggattattc aaaagagcca gtaaatgatt actttttaat cgatatgaaa agcttttacg
     1621 caagtgtcga atgtatagaa agaaatttag atccattaac aacagaactt gttgttatga
     1681 gtcgatctga taatactggt tcaggattga tattagcttc ttctcctgaa gcaaaaaagc
     1741 ggtatggtat tacaaatgtg agtagaccac gtgacttacc acaaccattt cctaaaacac
     1801 tacacgttgt tccaccacgt atgaacctat atatcaagcg aaatatgcag gtaaataata
     1861 ttttcagaag atatgtggct gatgaagatc tactgattta ctcgatcgat gaatcgattt
     1921 taaaagtgac aaaatcactg aatcttttta cgactgaaga aacacgaagt cagcgaagga
     1981 agaagctcgc tcaaatgatc caagaacgta ttaaagaaga gttaggtttg attgctacgg
     2041 taggcgtcgg cgataatccc cttttggcta aattagcctt agacaatgaa gcaaagcata
     2101 atgaaggatt tattgcggaa tggacgtacg aaaacgttcc tgagaaagta tggaatattc
     2161 ccgaaatgac ggacttttgg ggaattggtt ctcgaatgaa aaaaaggctc aaccaaatgg
     2221 gaattttgag cattagagac cttgctaact ggaatcctta tacgattaag aatagattag
     2281 gtgtgattgg attacagctg tacttccatg ctaacggaat cgatcgaaca gatatagcaa
     2341 tcccgccaga accgacaaag gaaaaatctt atggtaattc acaagtgtta ccacgagatt
     2401 atactagaag aaatgaaatc gagctggtgg taaaagaaat ggcggaacaa gtagccattc
     2461 gtatcaggca gcataattgt aaaacaggat gtgttcattt aaacattggt acgtcgatct
     2521 tagaaacgag accaggattt tcacaccaga tgaaaatacc tatcacagat aatacaaagg
     2581 aattgcagaa ttattgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc
     2641 acgttggaat aacctatagc aagcttgtgt acaccgattc gcttcagctg gatttattta
     2701 gtgatccaca aaagcaaatt aacgaagaaa atttagataa aattattgac aagattcggc
     2761 aaaaatatgg ttttacgtcg attgtacatg cttcttcaat gttagaaagc gctagaagca
     2821 ttactagaag cacacttgtt ggtggtcatg cgggcggaaa tgggggaatt aaaaatgatt
     2881 gattacaatg atcgtggacg tttaaagtgg gcagggtttt atttatctga tcatactgaa
     2941 gaaattgatg ccgacaatga acaacgaacc agtcaaaatt tagcaaaaga acaaatgacg
     3001 actgaagaga ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatctatt
     3061 caaaaagaag aacgaaacgc tgaaggatac tatccagaag atattgttgg caagatctta
     3121 ggtagtgatg agctggggat ctacgttgga aaagacaaaa ttcactacga cgaaatacgt
     3181 catatcgaat tttaccagga taataaatgg agtcgattag aatgaacatt atccagcaat
     3241 atgagctaaa gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccaac
     3301 gtttgataaa tgaggttggt gttgagcgct tctctttcta tgtagaagct gcagcaggtt
     3361 atcataattt taggttttat attttcccgt tatatatata aggtatttta cggattctat
     3421 agagttatct ctatgaatcc ttttttgttt ttacaaatag gagtagatac tagaataatg
     3481 cgtgtgttaa actattattg caaacgcaat aataaaagaa agtaggctta cgcaccatgt
     3541 ctatcaatac atttgtttac tcgcacccga tcaatgttta cattatcaag aatttaggaa
     3601 tcactgtaga acaattttgt gagttatatg cctacccaca aggaacggtt gcaagctgga
     3661 taacccgaca acgtagaata aaatcattac ctgcttcatt cgtttatgat ttaagcctgg
     3721 cctctagttt aaacatgtct gatgtttatg aaaagctcct gtctttagaa aaagaatatg
     3781 attccttcaa gattaaacat gataaaaaaa taaaaaaaca tatataatat caatcacaat
     3841 tgtataatat tacgatatct taatatcatg atatcgtaat attgtttttt tctaagaaaa
     3901 tgcactataa gaagggaatt attagtaaca atatagacag tttaataatg tttaaattat
     3961 tctagttgct gctcgcaaaa catatttctt atgattaata aaaaatttta aagtaataaa
     4021 aagtgattat tttactttcg aataacatat gaataatctt tatatccgaa ccgatatata
     4081 tctttaaaac aaaataatca cacaatatta caatataatg catatacgat attgcaatat
     4141 cacaatatta tgatataatt atattataat ataagatgaa tgggggatat tttaatggca
     4201 agaatattgt cagtagccaa tcaaaaaggt ggagtttcta aaactacgac tagcgttaat
     4261 ttagcagcat gtttgaaatt tgtttacggt aaaaatgtac ttttagtgga cattgatcct
     4321 cagggaaatg ctacagataa tgtaggtttc gatatagatg gaacaaacca acctacaatt
     4381 tatgaagtat taaaagggga ggctgacatt acagatgcta ttctggacta taaaggaatt
     4441 gatgttttgc cagccgacat agccctttct tctgcagaga gggaatttac tcaagtagga
     4501 agtgaacaca ggcttaaaag agtacttcaa ccaatcaagg acaactatga ttatattata
     4561 attgattgtc caccaagttt aggaatgctt acagtcaacg catttactgt ttctgatgaa
     4621 attatcattc cagttgaagc tgcgtatttc tcattaaaag gactaataaa gttaagtgaa
     4681 actattgaaa cggtaaaaga atatacgaac gacaagcttg aagtacgagg agtcctattt
     4741 actaagtata ataagcgtta taacatttct aaagaaatga cgactgcagc aaccgaaatt
     4801 tctagagtca ttggtgcaaa aattttcaaa acttatattc gtagaacaat aaccgttgac
     4861 gaagcgcaag ctgctggatc agatctaatc aattttaata aaccctcaac agctgaagat
     4921 gactataaag catttacaga agaatattta aaagaagttg gtgattttga tggcagaaga
     4981 taatcgcagt caagctgcag taagtagact actaggaaat aaaaataaaa agaactacaa
     5041 accaaaagaa gtagaagaaa tcgaattaac caagaaaaat ataagtaaag tcataaaaga
     5101 tcaaggaagt agtgtaagaa cagcagatag cattcgtata aatccaattc taatgtcagc
     5161 actcaaatat tggacgacta ttgctgaatc agacaaaagt aaaccagacg ttatagaaga
     5221 tgcgctatta aaatccatac ctgaagaata cttgattgaa ggatataaac tagcaaagaa
     5281 acaaaataaa atttaattta cattcaatat cacgatatca taatatcgtg atattttttt
     5341 tataaaaatc agtagtatca aagctgataa gtcgcttatc ttcatattgt aatattacga
     5401 tatcgtgata taatgttatt gtaatatcgt gatatagtta ccatgagctt aaaccctgaa
     5461 atagagcggt ttgctttaat ttatttttta aggtaaacta aaaaaagata aaaaaagact
     5521 actgctttaa caaagtttgg cgacttatca gcagtagaaa aatatatagt ggatagatat
     5581 atttgtttaa ttcattgtaa catagttttg aacaaaacgc tatcctacag aaagaggatt
     5641 ggctatgaat gattttaatt attacaaatc aaaagaaatt tatcgtgaaa aatattatca
     5701 aatgcctaag gtatttttta ctaacgaaaa atacatggat ctttcaaatg atgcaaaaat
     5761 tgcttatatg ctacttaaag atcgatttga ttattcagtc aaaaataact gggtagattc
     5821 tgatgataat atattcttca tattcacagt tgaagaatta atgaaattgt tacaatgccg
     5881 cgaaggtaaa gtatctaaga tcaaaaaaga attagaaaaa gcaggtcttc tgaaacagaa
     5941 gagaggaaga gtaaataaac gtgatggtaa gattgaatct atgcctaatt tattgtactt
     6001 aggcaagcca gaagttacga atcaagacgt ctttaaaatc atggaagagg aagacaatac
     6061 tgattccacc gtaattgcga aaatcgcaaa tacggcaaaa ccgcgaaaaa tcaatgattc
     6121 taccgtaatt gcgaaaatcg caaatacggc aaaatccagt catatcaagg actcaaccgt
     6181 aattgcgaaa atcgcagaca atctattcta ttctaattct atagacacta atagacacat
     6241 aatagacact gaaactgacc agttacaaaa tcaagttttg ctagataact tcgtcgacat
     6301 catgcaagag gacagtataa atacatttgt accagaaaat gtattaaact tgataaaaac
     6361 attttcttca agttacagtg aagctcaaca aaccgtccaa actattcata atgcaaagaa
     6421 aaaagctgaa gaattagagc aaactattgt cgtttatgaa gaactggaat cttatggaat
     6481 tgatgctgac aaaggattat atatgacttt actgaaagct tatcaaaaac aaaaaactga
     6541 aaaagtaaac aatttgcaga atctaatttt cgtttatgta aaaaattggt ttgtcgaaaa
     6601 agctattgcg gcaaagcttg caaacgaaca aagagaaaca tttaacgaat taccaacagt
     6661 tagtacggaa aattggttag agtagttgat aaaaagcaat tactataaaa atgatcaatt
     6721 ttaaattaga acttttttat gattttaatt ttattacaaa tattacaaat aaatagttag
     6781 tattccggag tttttagatt aaaagtttat gaaaacaatc acaatcgtag gttttaaatt
     6841 cataatcgtt agatatttta gttatttttc actcaaaaaa atagggaact agtgtttgca
     6901 tatgtgcttt tttgagttat aataattcat gaagagaggt aattcactta tttccccaag
     6961 ctgaaaagcc tgatattact tcttttcagg cagtgctgct aatattcaat tacacttttt
     7021 tgtatatttt tagttgtttt aaatttaatt gtctgctatg cttgtgatga attgattttc
     7081 gttctgcact tttggacgat aaatttggac aattgaaaat acaaaaaaaa gaaaggccct
     7141 gtgagactcg gaaggctggt aaccttcgtc gacgtccaca ggtggcatta agatcactcc
     7201 cttaatgcgt ttacctttca gtgttacggt attacccgta acggatttag tataacagat
     7261 attcaaaagt gataccactt tttttggctg tgttaaggtt aaaaatacgt gatattacga
     7321 tgaatctatg cctaagcata atgttataaa aatgtccgtg tggctctttg ccgtatgacg
     7381 aacgctgaaa ttagagggaa cgcatgtttg gatgcgttcc ctcttttttg tttgtcatga
     7441 acgaaaatca attctctatt tttgaaaaat aacaagaaaa acttgttaaa aatatttaaa
     7501 gtaagtgggt ggattatttt atgtcatata caggaatttt gagtctcgaa gatatttgtc
     7561 actacggtaa acggtgtacc gctacagaaa agatcacgaa gaaactatca actggtcaaa
     7621 gtaaaaccgt tgtgcagtgt aagaaatata taatccagaa agacaaagtc tcagaagaaa
     7681 tgatttatta cattgggaaa caaaaacaaa taattttaaa agatcctatc cctttaaaag
     7741 agctatatcc aacaatcaaa catgtttatg accaaaacgg tgtactgatt ggtcgaagaa
     7801 aaaatggagt cttgcgttgt accgcaaaag ggatggggcg tttaatcagc tgaattgatc
     7861 attctcataa cttgtatttt atcgtttttc gcttgcttga aaatattgtc gagacttcta
     7921 aaggaactta gaatcactag aaaaataagg agtagacttg atctatcaac aattcctttc
     7981 ggggggtgac ggggtaggtt tttacgattg gtaacgtaaa aaattggtca atcgagtaaa
     8041 tgcccttgtt tggatagtgg tgaaatgaat ttgtgtaaat aatatgcaca gagtaaacaa
     8101 gagggaattt agaagttaga caagttagaa tagcgcctag attaatcatg agcagctact
     8161 aagggatcta ggctttgacg caaactcatg gaataaggag taggtcttct cgtaatgggg
     8221 aggacgcaca agaaattgtg tcgtgtgctg cagtacatgt agatacttgc gaagacgttg
     8281 atctttggat caatcgagca tttaccgttt tctactaggg tttctcgttt cggacgccat
     8341 aaacgagtcg atttatttta tatatttttg agtgaacgaa aaacgataaa aatattcgtt
     8401 atgaagtaaa actaatttag tagatagcaa aggtggtaga ggaatgattc aaaaatttgc
     8461 gaaaatgagt aaaactgcat ggattgaaaa gcttgaaaat gacttgagtg tcatgcgatt
     8521 agctccaaag aaattcaaac gagagattgc agaaaaagaa gcaattttgt cggtattgaa
     8581 tgcggtagac gataaatgtc cagtaaaaat tagtttttca gatatagcaa caattatcga
     8641 aggtatttat tatggtgaag ttgatgaaga gatatcttct acaaaagatt tattagattt
     8701 tttggataaa aacaaagata cctttatagt actaactgat tatgaggagg ttacaacaaa
     8761 tgaaaaatta tgatccgaat agccgatggg gaacacatac gattaaggtt tctttccaac
     8821 gttgggatta caaaggattt gtgacgttta gaagaggcgg aaattgtaaa ggattagatg
     8881 ttttagcatt agacgaggat gatttatacg atcaaaaatt gactgataat ccaattggat
     8941 tcggcttgct acctgaagat gatcaaggta atgaatggtt taaaatgacg cttatgaatg
     9001 ataatggaga cgaattatct gttgaagata cttggtcata tttgagtgat tatattgtca
     9061 gcgttgaaat cattgaattt gtagcggata aagaagaata aaaactggag gaataaattt
     9121 tacagataaa ggcttagaag gagtcacgac gattaataaa aaggtagtat taccttaggc
     9181 attgagtaag gaatttattt aggaggaaaa ttagatggcg cgaccagttt tagaggcgat
     9241 ggatatggat actttgacaa aaggaaggta tgtacagctg ttagctcgtg gttattcacc
     9301 taaagaagta ttcaaatccc tgtctaaagg aacagatatg gaaaaagaaa gattacgaaa
     9361 agaattcgat tattggagaa cccataatgg aatcaaggat ttgaaaccag cacggccagt
     9421 aattaaacga aagaaaaaga taacccaaga ctgaagtgta gagcgtatgt gatcataggc
     9481 ttttttattt ttgcaaaaaa caaggaaggt aggaaaactc atgaattatg aagaaatcga
     9541 aaacagaaaa aaagtgtcga aagaaatgga agaaaagttg ctaaaaacga tgaaacaaaa
     9601 acaccttaaa agattatctg tcatgcaata tatcaatgat atgcagataa caggaaaaga
     9661 gaaagcttgt ttgttaggtt caatgaaaaa ctttgaacag ttgagacgaa cttatgtgaa
     9721 aaaaagttct aattgtcaac tattgttaga agtctcatga cattcattaa tagaattcat
     9781 ttttaaaact ttttctatgg aaatgagaaa aagatttttt gttttgtctg aaagggggta
     9841 gctggatgag aaaatggtta tttggttttt taggagtcgc tttaatcgtc ttttgcagtg
     9901 tgtttggcta tgttagctac caaaaacatg aaggaaaggt gtttaagcaa aatatagaaa
     9961 aaaagatgcc cgtagatcaa atcaatgaac atgcaaagag ttataaggag gatgcaacga
    10021 acgtcaataa tgatatgtct ttggggcaaa tgttgtccat acaaaaagaa gcaatcgaaa
    10081 tgggtgtcaa taaacaagcc tttgcacaaa ttcagatacc tgcacttggt ttagcattgc
    10141 caatttttaa aggggcaaat caatacactt tgagtcttgg agcggctact tatttttatg
    10201 aagatgccga aatgggcaaa ggaaactatg tcctagcagg tcataacatg gaaatgccag
    10261 gtgttttatt ttctgatatt caaaagttgt cattagggga ggtgatggac ttagttagta
    10321 acgatggcgt ctatcgttac aaggtaacgc gtaaatttat cgtacctgag tactttaaat
    10381 taatcgatgg cgttcctgaa gagaactctt tcttgtcttt accaaagaaa ggagagaaac
    10441 ccttattaac gttgtttact tgtgtttata cgtcacaagg aaaagaaaga tacgtggtac
    10501 agggagagct acaataacaa ggttttaatc aacgcgagtc gttgaaatat gaaatgagga
    10561 gagtaaaaaa tggcaataaa tcggtatgta aaaaaagctg gaatgcttgt tggaatgtta
    10621 ggaatcattg caagctgctt tcaggggtat caagtacacg cagaagatgt cacgcaaaaa
    10681 acaccaccag agaaggtcaa tatcacggtt cataaattaa tgtacgatca aggaacgcaa
    10741 ttgaatgttg atattgacgg gatcaaaaac gatggttata cgcacgatca atatcctaca
    10801 ggtgtaacga aatacaacaa ggcagattat ggtgatgttg agtttacgtt aggaaatatt
    10861 acggatcaag tattaccgag agaagattct gatctaacca acgcgaaagt ggacgagatt
    10921 gtacaagatg tagaagacaa gggatctaac agtgagtacg tcaagaatgc aaccaacaaa
    10981 attacttcag ctgtagatga aaatggtgag atcactttta ctgatcaacc agcctatgtc
    11041 aattccaaag ggaatgtata tgtggtttat gaaagtaaat ccgctgctgg attagtcaca
    11101 caaaaagcaa aaccaatggt tgtgattgcg ccaatgacag ataaaacagg atcaggattt
    11161 ttaaaaaata ttcatttgta tcctaagaac attgtttcta agttgagttt tgaattaacg
    11221 aaatttggtg acgatggcgc agcccaaagc aaacaaaccc ttttaaaagg ggcaaaattt
    11281 gagttataca agggcgaacc tggaaaagga acaaaattgg gtgatcttgt atcggatgat
    11341 caaggaaagc tgactgcgac tgatttgact ttaggaaaat actattttgt ggaagttcct
    11401 tcggaagttg tagtgggatc agatcaagaa ccaacagcag atcaatattt attaggcgca
    11461 gacgctcgca acgatgcgca taataaatta acctttgaaa ttaccaatga cggcgtgaca
    11521 agtgacttaa aagcttccta cgtgaactat aaagcaccag tgatcgataa aacagtgaca
    11581 aatggaacag gacaagaaca ttctttccaa attggtgacg cagtgaatta tcaaggaacg
    11641 attcatatcc ctacagatat tgcaggtgga acagatggga ttacagtaaa tggtgtgaag
    11701 agtgaaactt ctccttacag cgtatttaag tggggagata cagcaggaca aggactttct
    11761 tatgtcgctg ctaaagcaaa tatcaaagta acaaataaag atggatctgt ggtattaaaa
    11821 gaaaatacag attataaaat ccaaaattca gaaaatggct ttgtgatcga ttttatcgtg
    11881 aataatggcc aagtaagtga tactgtagca agtttacacg gacaagatct tcaaatgact
    11941 tataacatgt atgtaaatga cagcgcagct gttgccaatc cattaacaaa tagcgtggat
    12001 ttcgtttata acaacaatcc atttaatcag gaagaacacc acgaaaaaac gaaagctgac
    12061 gttgtgactt atggtgcaaa attcttaaaa gtcgatagcg gactatttgg aacaggaatc
    12121 aaagcaacac cgcttgaagg cgcagaattt gctgctaaaa acgcagaagg aaaatattat
    12181 ggtggattag ttgatacgga taaagacggt gtcaaagaag cagtatgggt agacgatgta
    12241 gcaaatgcag cgatcctaaa atcagataaa gaaggtcact ttgaaatcac tggtttaact
    12301 gaaggtgaat attcactgga agaaacaaaa gcaccaactg gttaccaaaa attaacagaa
    12361 gatattgcat ttaaagtaaa caaaaactca tttaaagagg aaaatcgaat cactgttaaa
    12421 aataatcaaa aagcagctat tccattaaca ggtagtaatg gtttccaaac gtatgtattg
    12481 atctcttgct tgttgctagg agcaggggca ctttctgcag ttgtttactt taagaagaaa
    12541 gcctagaagg atcagctaat gattattcgt aagcccccaa aaagaagagt catgcacaaa
    12601 ctgatgatat ttttttggtt gctgtcggca gtagcagtct atttaattcc agctgtggaa
    12661 acaaatgtag cgaaatttca acaacagcaa agaattttag ccattgaaaa tcttgaaaaa
    12721 acagattctt ctttggatgt tgcgaaaata gagttaggcg atcctgttgg tgttcttaca
    12781 attccaagta ttcctttaaa actaccaatt tatgacggaa cttccgacaa aattttagag
    12841 aatggtgtag ggattacgga aggaactggc gatattacag gaggaaacgg taaaaatcct
    12901 ttaatcgcgg ggcacagtgg actttataaa gataatcttt tcgatgattt gccttcagta
    12961 aaaaaagggc aaaaattctt tattaaggta aatgaagaac aacatgccta tcaaatttat
    13021 cgaattgaag aagttaaagc agaagaatta caaaaaaatt atttagatta tctcatgcct
    13081 gaaaaagacc aagataggat cacgttaatg acatgcacgc caaaaggtgt taactcacac
    13141 cgctttttag tgtatggtga acgagtgtca ttcagtaaag aagatttaaa actacagaaa
    13201 aaagcaaaaa aataggaaat caatttcatt ggattggcga ttagcactgc tattcgcttt
    13261 ttttgcgttc ctattatttt tatttataaa aaaataagga ggagatcgga atgaataaga
    13321 gaaaatggct gtttgtttgt gtagcagctc tctttgcaac tgcagcttac tcacagatat
    13381 cttttgctga tagcagtact actccaacta ccagtcagac aacagatagt tcaacaactg
    13441 caacaagtga cacggacagt tcgaagaaca ctgcagaaga aacggcagat tcaagtacga
    13501 gttctactga atcagcggaa tcaacgtcag aaagttcttc agagacttca gaaaaactgc
    13561 aagaagtaga agatacgcaa gtaatcaagc aaaacattca tattcaaaaa attatttctt
    13621 cgaatcgaat caacaatcaa ggaaggcaag tgactcagca agaaggtgtc aatggtgcaa
    13681 agtttattgt ctacgatatc acgaatatct tagaagaaat gacacaagat gataatgaga
    13741 aaaatcaatc ggtagaaata attgagtcaa aattgaaaga tcgagcaaaa aaactttcat
    13801 acgatcagtt gaaaaaagtg actgaaggag aaacccaaac aattgatgat caggaaggcg
    13861 tgattgattt ttcaattgaa gtacctgcaa acaaaaaaca agcatactat atcgtcaatg
    13921 aatcaagccc tgaaaacatt tcaaatagcg aagatattgt tttattgaca cctgtttcag
    13981 atgaaaaggg tgaatttttg acggatgttt ggttatatcc taaatcaaag aaatcagagc
    14041 cgaaagaaga aattaaaaaa gttgtatcaa ctggtgtaaa gaaaaacttt tttgataatt
    14101 gttgggattt tttcactcat ttatttttta acgattagga tgaaatgatg aaaataataa
    14161 aaatgttagt ttttaatcta tcttttttag ccgcaacaat attgtgttgc ggtttagttt
    14221 tttctcaatt atcaatttac ccaagatatc aacgattgtt cgttcatttt ctaaatatcc
    14281 agcatgcttc catgccacta gaagtgatta acaagctctt aatcaatcca atttttatgg
    14341 ctagtttgtt tcttcttgca ggattggtaa cgtgggtatt aggaaaaaaa gaatgagaag
    14401 cttacaatcg tttaacaaaa taatagatgg agggcattat ggaaaataaa attcattgca
    14461 ctacgggaag agtatttact ttagtgttgt ttttgttcct tcttcttttt gcaaggggaa
    14521 ctgcagtcca ggccttagaa aaagttgatc cgagtcaaat caaagaaaat aataatctgg
    14581 tactttatca tgatagtgat tcattgagaa atatcgaagt aactgggatc aatggattta
    14641 agatactaga tgagtattca actaaaaaac aaaaagtact tgcttggcca aaagtcaaag
    14701 atttgaaaag cacgtcaaaa attgttgccc attatcaaaa ggtgggcact tatctaggaa
    14761 aagaaattga ttgcgacgta actttttcta attttgtagc gcacgctggg gttaaccaag
    14821 acggattagc taaaacaatt aatgggaaaa agtattataa ttatttgctc tttgataaaa
    14881 acatttatcg aggctttttc atgcagtcaa tcaacgttat gaatgttaaa ctagatttta
    14941 agtatgcagg atcaaaaaca aaagtagctt tgagtgaacc acagccagaa attaattcaa
    15001 aaatgagatc gatgagagca gctggtattg agttgaatga tacatttcta tctatttaca
    15061 gtttaaatgg acagtatcag caacgtgtgt cttggtataa tgacaataat gaatctgtcg
    15121 gtgaacgtaa tattgatatg agagaatttg ttgggtacga aaaaatggat cgcttacctt
    15181 attttgtcac aacagataca gcatgtgcag aatacaaagc tcctgcgtta tcaacaaaca
    15241 atttaacttc aaaagtagtg ggaggacgtg cagaaaaggc ttatagctcg aatgatcatt
    15301 tcaccgatgt tgtaggagct gatacttatc acagaagtgg tgtaacgtat acgcttcaag
    15361 gcgcttcccc aacattcatg attggcgcaa atacgaatag tatgatgttt agctttgata
    15421 ctgcattgct ttggacacca caaccatcga agcctacaaa agaagtgttt aacaaagcta
    15481 atactgaaga ggcagcacac aatattgaca aaaaagtgat tccacaagga tcagatgttt
    15541 actatcatat tcaccaaaag tttgatgcat taacagtcaa cacaatgaac aaatacaaat
    15601 catttaaaat cactgatacc tttgacagca aaaattttga tatggtatcg gatgggaaaa
    15661 actatgatgg cgcattgtgg tatgttgaag cgaatgggac ttggaaaaaa gctgatacag
    15721 gaggaaaatt aactgtatca ggtaatacag tcacttatac tgcttctgac agctttttag
    15781 ctaatgctgc aaattacggt agggactaca ttttgcagct ccatatgaga gcaaaaaatg
    15841 atgcaaaagg aattgcacca aatgtggcta ctgtaacgtt taacaatgat ccgaacaaag
    15901 gaacacaaaa aacaaataaa gtagaaaact atttctctct taaaccaaat aaaaaagtgg
    15961 aacaagatgg gaaagatgtt gatggtcgaa atgatggtaa aaaaggaacg cctacagctc
    16021 ctttaaatgc aggatctgaa gtacaatatc tagtcacaca aaaatggcat acaaaaggtg
    16081 tagacattgc gctcgatcat tacaagcaat ttagtattca agatccagtg gaagctcgtt
    16141 tgacgtataa agaaggttct gcgcgagtga tagatatgag tacaggaaaa gatattactt
    16201 cagaaggtat actaacctat gatagccatt caagaacgct gaaatgggaa gcttccgctg
    16261 atttcttaaa taacaatctt ttagatggac gagaaattca actgatattt acagctaaaa
    16321 ctcctttgaa tgaagaattg gatatcgaca accaagcaaa agtttcagta gaaagtattg
    16381 agaaagcaac taatgtagta acgattgggg taaaacctaa cttacctcag gtcattgtgc
    16441 caaaaactgg atcgaatcat ttagtgctaa ctgttattgg aagtatatta tttcttactt
    16501 tagcatcatt gggctatgta gttttaaaac tcaaataaat ataaaaacaa ggctgatttt
    16561 cagccttgtt ttcttttatt tgaagattgg attcgcacta ataaatacat tatctacgcc
    16621 aattctacca gcagagtcaa ctacaaaatt atgacctaat ccgagaatac tttggttatt
    16681 ataaagtaaa tttgcattat gggcagggct atttttccat cctaccatgg catcgatagc
    16741 accatcgtct gataaaaggt catcaatata cagcccagtt tgacttatgt tttctccctt
    16801 agcaccatag cagcctaagc tttccaataa atcttggaaa gtaccaccac cagggcgata
    16861 gtgactgaag ctgacttgta attctttagc tcgaatatct gcagcctgtt gaacaatatc
    16921 attgaattgc attggggcaa caccattttg ttggcgataa tcatttaacc aagcaagttc
    16981 tttttgacgc ataaagttac gtaattcgtc taatgaaatc tttttatatt tgaatgtgat
    17041 tgttttattt tgatcgacgt tattaatgga tcgttggccg tttttatcca cggtaacggt
    17101 aggatcgtca tttctgcaca agaaataatt ttgatcagtc atatttttcc aaggagtaga
    17161 gaagctatcc ccttcgtata ctgtttttga ttcactagag agaacagcgt tggtatcagc
    17221 atttacatga ttaacagtca cattaaattt acgagtgtag ttgaaaatat aattttgact
    17281 ttcagtcaca ttgtttaagg ttactgaatt tgttggttct acccgatcgt ctaaaacata
    17341 tccttgaata gaaggagcag ttaaagtgac actttcaccg tgagtgacgt tgattatctg
    17401 ttctttcaaa atatcaactc gcccctcatt tttgtagttg ttattgcaca acaaattgat
    17461 ttgatgcact tgattataat tgaatgtgat tgttgtatta cctgtgattg ttttgctttg
    17521 agtatcatta ccaatcactt tgtagctaaa attatcttta gcaccttcgc tatatttaaa
    17581 tgcttttgcc ttagcagtgt aagtagaacc agaagtcact tttgcttgat ctgtagcaat
    17641 cacttgacct gtttgattgt caatatggtt aatggtaacc atatattctt ttggcgtttc
    17701 aggtttgtgt tgcaaccctt taaatgcagc atcaagacta tttttagcat tgtttacttg
    17761 tgtttgagaa accttagaat cgtctagtac ttttttagca ttggataaag cagtctgaaa
    17821 attattccaa gattcttctg taaaatctcc tttagcagtt gattttactc ggttgtataa
    17881 agcttgtaat tcagctttat tcacagtagg aactggtttt ttctttaatc ctttgtaagc
    17941 agaatctaat ttatttttgg cactatccac ttgcttttga gtcgcttttg agtcatttaa
    18001 cactttctta gcattgttta aagcggtttg gaatgcgttc caggtattgt cggtatagtc
    18061 accttttttc gttcccttaa cgctcgtata aagagcttct agagccgatt tattcacttt
    18121 gggtttagag gtgtcagcgc cataccaacc gataccttcg tatttccagc catagtcttt
    18181 ggttaaccat tgtacttctt tccaacttgc agtgtagtga tgtgagccag attttacacc
    18241 aggaaggaaa aggcggtaga tcggtttatt atttttttcg gcagaacgcc aggcaggccc
    18301 ttcataagtc cagccgtaat ttttagtcaa ccatttcact tcatcccaac tagctgtgta
    18361 atggtgatca cgaagacctt tattgtacaa acgatagaca agatggccac cgctagtcgg
    18421 tgcttcccag gcggggcctt cataatttcc ccattttatc tttactagat ggtcacgttc
    18481 ttttttgcta gaggtgtaaa aatgttcatt attatttgga ttgtaaaggc gatacatgac
    18541 gttagttgaa gcagcgtcaa cagatccagc aagactaagt gaggcagcaa atgttccaat
    18601 agctaaaaca gtttttggat taaataattt cattttttca actcctaaat ttaattaaaa
    18661 atgtttacat gattattata tatcggttaa ccgatatagt caataaaaaa taagaaaagc
    18721 cttatataat tttggctttt cttattttat ttgttagttg aagtattaat atcaacgatt
    18781 tcttcagcca atttatttaa tttcatagca tttatgaatc tcatgttgtc tatactagag
    18841 cgtttgttgg caaggtcact tactgtagtt aagggtacgc cagattctat ggatatagaa
    18901 cgaactgatt taccactatc aaacagcaac cattcgattt tctttttatc agcgtacatt
    18961 tcaatgctcc ttcttgtttt ttctttatta tagctctttt ttgtaatgaa tcacaatatc
    19021 aagagaaaaa ttttctatag aaaggtggat ttttatgagt attcgttctc cgtgtatcca
    19081 aatgaggttt gttgctactt tcgttatttg atatactaaa aataaacaac gaaagaagga
    19141 ataaaatgaa gaaaaagcaa ctatggtttg tctctatgtt tgcaatattt tttattattt
    19201 taagtggatg ttcaagtaat aagaaatcgg aagctaaaga agataatagt ttattgcaac
    19261 caggaactgt ttggaaagaa gaagtaggtg gtcttattca taatttaaaa attatagatg
    19321 atactacctg ggaatattct gaaagtgtat ggcatccaga tcctgtacaa ataacagtta
    19381 agaggcaaaa agactatgaa ggtttagaaa gatacaaaat agtagattct gcaggcatta
    19441 gggaatttat aaacaaacct gattcattat ttattgttgt tccctatgag aaggatggcg
    19501 taaaaaaaat aatttttctt ggatctagca aggatgagaa gcgaacgaaa gagaaattaa
    19561 ttcatgatgg atcacaatca aataaataca aattacaaaa gactagcgag tgattgctag
    19621 tctttttatt tgtcctgaag gaggaatcac agtggcaaaa gctaaaacgc catttgaaaa
    19681 agccgcgtct aaaatcttag aacgccgcgg tgtatctgaa acacagtgga aacaagaagt
    19741 ccttgaaaaa gcacaatttg acctattacg gggaaaagac aaggacttag aaggatatat
    19801 ctatcaacgt gaacgtgaaa agcttgtttt cgatgaaatt attaaacact aaaaggagcg
    19861 aacaatttta tgtttgaatc aattacaatg aattttttaa cacaaccgaa agtagtagct
    19921 gcggttgata tttttagagc attacaaact gccgcaacta gtttgaaaaa taatctgatg
    19981 atttttgctg ctgttgcggc agtggcttcc attgctcttg gaggtatttt cttcttcttt
    20041 gggcgaagag gagctgaaaa cgggaagaca cacgtaggtt atgtattgtt gggggtagga
    20101 gttattttag ctgccgcttc tattgtagtt tcaatgttct caatgtttgg acaaacccca
    20161 caaggactat aaaaaaacaa gtagaaggag taaaaagtac gtggctactt tttactcctt
    20221 tttttatgga aggagaatat tcatgttttt tacgatttca ggcaatgcaa aattggataa
    20281 agagttaata agaaaagcaa cgaagaaagt gggaaagcgt acttcctttt taccgaaaac
    20341 aattaaatat tctgtcattg aaacggaaga acagctacat gtgttaggac aagtgttaga
    20401 acaagagaat caatcttctg ttaaattgac tctcacgtta catgataaag aaggaaaaat
    20461 agaaaaggct ggcacagaat acgtttttgg ctcactggat tatcaaattt cagaaggttt
    20521 ttatcctaca ttgattgatt taatccgcct agatatattt aaagatacgg atgaaaccat
    20581 gagtgtggaa gagtcttatc gaaacgaaaa aattttacaa gttttagaag aagagttaga
    20641 aagcgaccaa agaaaagtga atcaagtgag tgaagtcgaa gcaaacgaag aagtaccatg
    20701 ggaacgccca atctttccaa aggatgaatc aaaagaaaaa gagaaaggaa ttattgacga
    20761 acaagctgac attttgactc ataaatcaat atttgaggaa gagaacgagg taatgggtca
    20821 attggaggta gatccctttg aagaaacaat ggaggatgaa gagacggccg aagtagaagt
    20881 tgatccagtt gaagctaatg aagacccaac atggactgaa ggggattctc aggaatatat
    20941 tgaaccactt atcagtgaag aagtagagaa aaatgaaaca gagatacaaa aggcaacggt
    21001 atttgattat attttggatc aatatccgcc agagcatgaa tggatgaaag aaaaaaataa
    21061 attattttta aatgaacttt attcgaaata tcaattacct caaacctatc aagcattttt
    21121 agagagtaaa gaagaattaa tctcacaggg taaaggcaca cttttagaac agttagagtc
    21181 tgtccaatca acaaattggc atgagcttgc acaagaagat ttattagcta cttttgaaga
    21241 acgtcaacaa gaaacagatc aagaaattaa tgagtatgcg acggaacagt cgtcgaattg
    21301 ggagaaagca aaagaggaac taaataaaga agaacagcga gtgattgaag aagaagtaca
    21361 aaaaattaaa gagcggtacg aaaagaaacg tgacaatgcg tattccttgt gtgtagaaaa
    21421 gatcaacaat tttactcaga cgaatcaaga agcattatcg aaagaaaaag aaaacttatt
    21481 aaaagaacgt ataaaagaac gaaaagaaga attttaccga gggttgcgta ctgataagct
    21541 aaggattagc aaagaattaa atgaacaact gaataaactc tatcaaacta cgactgaagt
    21601 tctgatggaa aaacacgagc agatccaaca agaattacaa gcacaaattc caaaatggaa
    21661 aaaagagtat gaaattcacc aacaagaatt gaaagaacaa gaagaaaaac aacggaaaaa
    21721 agaaaaagag cgcgaacaat tagaactaaa aaaacgtgaa caggatcttg cggaacaaaa
    21781 aatggcgata gaaaaacaac ggctagaaca agaaaaggaa aaagaagcag ctgctcgtaa
    21841 ggaacgtcaa gaacaaatgg atacattgcg acaagcacag ttaaattatc tgacacatcc
    21901 tcaaccagta gctgctgttc aaacgccagt gaacaaccaa gcaaatttaa ctccttcacc
    21961 ccagcgttcc tttaacggat ggatggtggg atgtattgca agtttaagct tgcttctagg
    22021 tggaggaaca gtatttgctt ttaatcatat caatcaatct tcacaggctg attctgtagc
    22081 cacaacggcg tcaatcaagg aagaagccca ggaacaagca agaaaagagt atgaacaaca
    22141 attagaagaa ttattgaatc gtaccaatca gtcaacaaca gagtcaagca tggaaaatag
    22201 caaagagagt gattctagta aggctaaaga aggatcaagc gattcaactg tacaatcaaa
    22261 cacttccgaa agttcagaat caaatgaggt gaaataatgc gtgttagaga aacaacgaag
    22321 cgaaaagaca aacgattcaa tttagaaaag aataggtatc tttctcattt ctatcgctat
    22381 actccctcag gagaagagct accagaaaaa catgacaaac gcatttcgaa aaagattttt
    22441 tatagtggac ttgtatacct ccctttagag tatttagtaa caagagtacc agaagttttc
    22501 aaccgattgg aaattgttaa gggaagctta caaggaataa atctgtttca attacaggaa
    22561 atgccacagg tctttcattt tgattcagct ggtttttgga atccatttac tcctacaact
    22621 agtttgggta cacgtttagc aatttcgaca gtttgtgtgg ttccagctgt acttatggga
    22681 ttgaaaatgg acatgtggtt tcgtcctcta gcagatggac aaaaagggga taatcgatta
    22741 atgaccttaa aagaaatcca acagatttat ccgcaaatac ctgaaacaaa aactactttt
    22801 ccaggttatg gaggtattcc aatcacacat tacaaaaaat attggtacat tcaaacagat
    22861 actgttaata cgtgtattgt tggtacctct cgatcaggga aaggtcagat tgaagtgtta
    22921 gccaccattg acaatttatc tcgtgcagaa aaacaaagtt caatggtcgt taatgatcca
    22981 aaaacagaat tatatgttgg tagtaaagat gaactagaag ctagagggta tgatgtatat
    23041 gcctttaata tcaccgatcc actgcaatca atgagtgata atccattggc actcatcgtg
    23101 aaatactgga aacgaggaga catagatact gcaacacagt taaccaatac tttcacaaat
    23161 acgatttatt atgatgccaa cgcttcagat aacaaatact ttaacgaaaa cgcgcagaaa
    23221 gctgtcaatg cgcttatttt tgcgttgtta gaacaagctg atcaaacagg agattactcc
    23281 aaattgacac cgaataatct cgttgagctt ctttctgaga ttggcggttt taattattat
    23341 ccagatccag acaatgaatt caaacagttg aatgccttag atgaatttat gaatcagttg
    23401 ccacctggaa acattgcaaa aaaacaatat ggggcaacga aaattggatc tgataaagcg
    23461 aagggaaata ttttatcaac ggcaatcacg ggattgaatc catttactct aacgaaaatt
    23521 gcaaagatga cttctcaatc aacgattgat tataaatcgg ttgggtttcc aaaatactta
    23581 gatttgaaat tacatgaaag tcttttaaat caacgagtcg tagtagaatt ttatcataag
    23641 ggaaagaaat ttcatgaaga acgtgtcaaa gtaggctata aaggatttag tgaaatcaat
    23701 tttgattgtc atttagttgc aggtgatcaa gtttgtttaa aatacgatca tcaaggaaaa
    23761 gaatatgtgg cttggtatga attttctcaa agagtattga aagacgaaga gggtaatatc
    23821 gtttatcgga aaaaacgagg agaaacccat ttgccagaat tagaaaaaga agccgttcta
    23881 acattagatg aggaaaaaag taacttatta gtagagtcta ttcggatgca ctataccgat
    23941 aaaccaatgg ctatttttat gcttacacct gattatgatc catctaacca tatcattgtt
    24001 agtatttttc ttagtcagtt atataaagaa ttatctacgc aatgtgttaa gactaaagga
    24061 gataaatgtc accgcaggat tcattttatt ttagatgaat ttgggaatag tgtgacctgt
    24121 ttagcctaag gataaaagag gctagttcca acgaacattg gaataacttt actatcgaga
    24181 aatcaaatga cggggtaacg ccctgaaggg tttccactga tactgcgaca tgcgttagta
    24241 ggatgtgcat ccaaacgcgt atgaagctcg ctgaagtcgg cagaagggta ccgtaaggaa
    24301 agacacgata cgtatctacc acgcaagtgc tctagaggta gggtatgtac ctgatatgtc
    24361 gggtgtccta aaaagttcaa taaggtgaga atgatttgat tatctgacaa acttgcgaat
    24421 ggaatgtctg aaacgaataa ctcatagaaa tgtgaggggg aagggggata cgtcctcttt
    24481 ccattgactc gaggttgagt aaaaatgtgt ttctatgaaa aaccttgcat ggttaaaggc
    24541 tatggagtag tcaacaggca aaagcaagca cctaagttga aatctatgga tagatagtaa
    24601 ggaacagggg aagcatctag cacggaggga gcataccgaa gatgtgtttc taaggaaaaa
    24661 ccgaaatcgg ttataactta ggtgaataga tgtgaaagta gagccacgac cagtgaaaat
    24721 ttcgtaatga aattggagga acaggctcaa gtcgttattt ataatataag aaacctattt
    24781 aaaatcatgg attctcgtaa gactaaaaag gtcacgaacc agaatggagc gtgataaaac
    24841 catgactaac acaaaaggaa ttagcttaaa gaacaaacaa ctcagacacg ccgaatacta
    24901 cgacatgact gagactttcg atgaattgca cgcaatgagt gttgcaaaat caaattttaa
    24961 aaatctcatg aaattcatta ttgatgacaa taatatcttt ctagcgtata gaaatatcaa
    25021 aaagaataaa ggaagtgcaa cggccggata cgatggtgtc actataaaag acattgaaaa
    25081 attggcatgt ggtgactttt taactattat taaaaggcga tttaaggatt acagaccaag
    25141 aaaagttaaa agagtagaga tcccgaaacc aaacggaaaa cttcgacctt taggaattcc
    25201 ttcaatatgg gacaggatag tccagcaatg tattctacaa attttagaac caatatgcga
    25261 agcaaaattt aataagcata gctatggatt cagaccaaat tgttctacag aaaacgccat
    25321 agcagattgt cttgctagaa tcaatcaaag taagatgaat tatgttgtag atattgatat
    25381 aaaaggattc tttgacgaag taaaccatac caaacttatg cgtcaaatat ggacaatggg
    25441 gattcgagat aaacaactcc ttgtaattat tcgtaagatg ttaaaggctc cgattgttat
    25501 gcgaaatggc aatgttgttt ttccaaccaa gggtactcca caaggaggga ttttaagtcc
    25561 actgcttgcg aatatatgcc tgaatgaatt tgattggtgg atagctaatc aatgggagga
    25621 acgaactgtc aaagagctga aacaccacta tcgaaaaaac ggagcatggg ataaaggaaa
    25681 tatctattcg aaattaagaa gccacacaag tttaaaagag atgtatctgg tacgctatgc
    25741 agatgatttt aaaattttct gccgaacagg agaagaagcc caaagggctt tttatgccac
    25801 acaaaaatgg ctcagagaaa gattaaagct cccaatttca atggagaaat ctaaagttac
    25861 gaacctaaat aaagctgaaa gtgaattctt gggtttttca ataagactcc acaaaaaggg
    25921 aaaaaagaaa gtggctttca cgtacgtttg tcgcaaagca gaagaaaaca ttaaaaataa
    25981 actaaaacaa cagattaaaa aaattcaata cgctggagca aaaaaaaata ggcaccgagc
    26041 aataggtgac tacaacatga tggtcatcgg tatccacaat tactatcgga tagcttcaca
    26101 ttgtagtgtc aatttcactg agatttatag aagtgttagg acagtaatag aagcaagact
    26161 gaaagctaga ggaatgacga aaaatggaat ctatggacaa gatcatgaag gataccgtcc
    26221 gtatctaaag tctaagcaaa tgagatatat tgaaggtttt ccgatacttc caattggcta
    26281 tattaaaaaa agaactccac tcaacaagcg gagaaatcta aataaatata ccaaggaagg
    26341 gagaaagctc attcatcaag agcaacaagc tatagaaagc tggaaaatca agtatcttgt
    26401 aaaaggtttt agtaacaata agaaatacac ggtggaattt tctgataaca aaatatctaa
    26461 gtttatttcc caaaaaggga aatgcgctat cacaggaaac gaacttttga tggaagaaat
    26521 tgaatgccat cacattaacc catatcattt gtccaaagac gatagttaca agaaccttgt
    26581 cattatctct agagaaatcc atagattaat ccatgcaact agtgaagaaa ctattctgaa
    26641 actgcttcgg ttactgaaac taaatcacta tcaaattaga aaactaaaca cgtatcgaaa
    26701 aaaagcagct aattttccaa tatcaatcaa aatgaattag ataggaaaca aattatattg
    26761 taattaacga tggaacgccg tgtgcggtga aagtcgcacg cacggtgtgg accgggggaa
    26821 aagacggaga taatatcaaa ctcttaccta tcggaattgc caccaatgga taatatggaa
    26881 ggaatcatga cggtcacagc tggccgaaac atgttgtggg atctgtttat tcaatcttat
    26941 cagcaacttt atgcgaagta tggagaacaa aacgcagcga ttatcaaaga aaattgtcag
    27001 acacatattt atattatgtc gacagatgat aataccatcg aagaattttc taaaaaagtg
    27061 gggaataaga cggttgaaca agagaacagt accatcaatt cattaggtat gaatactcat
    27121 atcaatcgca atgttgattc agatcgtatc ttaactcctg aaagaatttc tactttttta
    27181 gaaggtgaaa cgattgtact cgctccttta aaacgacaag atttgaaagg tcataaaata
    27241 cggccgtatc ctatttttaa tcatggggaa acgaatcttc cttatgctta tcaatatatt
    27301 gaagatttca atccatcgtg ggatatcaat gatatagaca tacattgtac acatgcggac
    27361 ttggatctta aggctttaca aattgattat gattatttcc taccagatga atatgctaga
    27421 aatctctatc atggactgca tgatcaatta gaagaaaaaa acgaagaaaa tatgttttat
    27481 aaaatcgttc aatctcttga gaatgagacg gctaaaaaat tgttaattca attttacgaa
    27541 gaacaagcag cagatcgact tcaagaatat gttgaaaagt tgatcaaaaa tgaagaaatt
    27601 tctgaaatga ttgggaaacg gttgttattg gaatctgaaa aggtggtgaa agaatgatca
    27661 ttggaggaat tttttctggc atagccgact ggtggtcagg cttattcgga gaaggggatg
    27721 caaaccccaa aaccgtaacg aaagtcttac aagattatgg taattatctg cagtatcaag
    27781 atgtgttcag ttggatttgt aatacttttt tatgggggtt gatcaaaggg ttatataatc
    27841 tcaatacttt actagaaaaa accatttatc aaagctttga tttaaaagac ttattgaacg
    27901 ccgctggggt aaatgaacta tttcaaagtt tgattagtaa ggtattggct cttttttgtg
    27961 tcgtcacatt aatttattta ggcttgaaat tttttatgag taaacaccca ccaaaagtca
    28021 aaaatatctt ggttaattta tttatggcca tgatcttgat ttttggtggt agttctttaa
    28081 tcgatgaagg gttaaatatc agtaaaagct tttacggaga cgtcactgca gcaaataaag
    28141 cagataaaac gggttcacct gcttttcaaa ttattcaaaa taatgtgatc gatgtcagta
    28201 cattactagc aactgacccg aataaagtag aatccctgcc aacagacaaa agaaatgctt
    28261 taacagcgaa aaattttaaa acagcgaata tcaatgggat tattactcct aaacaagcta
    28321 aagaaatggc ggataaagat aagagtggtt tatcagattt acaaaaggat cggttaagag
    28381 cgttacaata ccgactggaa ctggatgata atggaaaaga aattcctgtg caaatcagtg
    28441 atgaaggctt agccaaatat gtttatactt cagggtatcg tcgatacatt agtagtccag
    28501 ggattatttt agctggtgaa tcttctttgg cggtggccta tttatttatc ctatttacga
    28561 tcgttacttg cattattgag ctggtattta aaaaattcta tttagtgatt gccgcgtcaa
    28621 cggactttga gacaggacaa cggatgaaaa gtgctatcga agatatttct caatccttct
    28681 tgttattggc atttacaatt ttagaattac gaatctatac cttaatgctt tcaggtattg
    28741 gtgatttgca tgcggcagga aagatcaatg gattcttgta tgttgtcgct ttgattgtac
    28801 taaccattgc gctattcaaa ggctctcaat cagttacgaa aattttcggc gttgatacga
    28861 gtctgaaaaa cggcagtaat tctcttctta gcatgtttgc cttaggaaat attgcgaaaa
    28921 atgtgggtag cggagctaaa aaccttgcaa gtgctggtaa gagtggttta agccatttaa
    28981 atgatattcg taaaaatgga tttggccatc gaaaagatgt tacccctgat aacggggaag
    29041 aacaatcaga cgataaagct acaactgtac ctaatagtaa gaaaacagtt tccgaaatgt
    29101 tcgggaaagc gaaaaatggt gtttctaaag ccgcagaagg tcttggttac gtcaatgaac
    29161 gtgggttaaa aggaacagct gaagatctta cagaaaaagc caaagacacc ttagaagata
    29221 aattagacgg cacgagagct aaagaattgg ctgaagctgt gaagaatcca tccgaagcac
    29281 tagaaaaaca aaaagaaaaa gcttcagaag tcaaagaagg actaaaagat gcgtatggtg
    29341 aaggacaagt caatgcagca gtgaaagcta atacaacaac cgaaaaagaa aatcaagaag
    29401 gtatagtgat tccttcagtc aaagatcacc aagaagcgtt gcactctaat gaaaattcga
    29461 ttgaagagaa aaattccata gaagaaagaa attcagaaga aggaaaaaat ggacagttac
    29521 caaaaactga tccagaacaa tatcgctata aacctaacag tgaccttgaa aatgagaagc
    29581 gaatttcaga tttatcaaaa gtaaatcaag aagacaaagc agaaaatgag ggacagttac
    29641 caaaaactga tccagaacaa tatcggtata gatctgttaa ctccgaaaat gaaaaacgca
    29701 tttcagattt accaaaacga aatcaagaag tacaaacgga tgaggattcc atcgttctgc
    29761 caaatgataa tggaatcgaa gttggaactg aaaaatcaac gaaaattggt ttacctaagg
    29821 cacaaaattt accaatgaaa gatagtcgtt tgaatcaatt caaggataat gatcaaagtt
    29881 ttgttcatca atcacctgca ggtactgttc aaatgaaacc aagtcgtttg cctgaaaatg
    29941 gaaatctgac aactgtttct tacaatttat ctgaaagtgg tgagacaggg aatgcgtccg
    30001 ttcaaaatgt tgtgacaaga gaagctgcac caaaacctat tcaaaacgtt catacaggtt
    30061 acaagccagc aaatgtggca tttactgcac caacaaaaat aaatgtgaca agagaaacta
    30121 aaaacaggaa caatgcattg aaagaacaac tattgaggga tatcaaacag gatatcaaac
    30181 cataaaaggc ctacaagtta ggccttttct ttatatgaaa aggagaaatc aattatggat
    30241 aaatatataa acatgaaaaa ccctccaaga tttagtggag aatggaagtt tttcgctttt
    30301 ttctttttag atctattaac gcttggtggc tgcttttttt gggcgaaaat ggtcaataat
    30361 cttgtccact taccactctt ttttgcactc ttgaattatg gcttatggat tgcgatagcg
    30421 ttagtgattg tttggcgacc ctataataac ccaggtcaac gacaaatttt tgcgattatc
    30481 gagtctattt tttttgcgga caagaaccat tatcatgcgt tagatcctaa ccgaaattat
    30541 catggtacgt ataaggagga tgaataaatg cgagtcaaag gacaaaattc agttgaaagg
    30601 aaatccattt tgcagtttgg aaaaccagaa gagcgctcta tcttggactt atttccgtat
    30661 aaatcctgta cagaagaggg agtcttaatt actagagaag atcattttca acgttattat
    30721 cgtgtagttt ctacagacgt ggaaggatta aatgaacaag agaaactaga acgaatgaat
    30781 cagttgacca ccgtcatgcg tacgtatgtg ccaacaatta agttagttag tttgaccaca
    30841 gagacggatc taacggaaca aatcgtgcaa aagcggcagt tattagataa aaatcgtatg
    30901 gaacagtcct taggaagaaa tctacagcga ttaagaaaat atgaaaagaa attagtagag
    30961 gaaatccagg aattgaaacg agcagaacag gaacgccctg atttaagctt ctttttcgtc
    31021 attgaaggaa agacaatcaa ggatttgcaa accagaaacc gtcagttaat gcgatctagt
    31081 ggcattttag ggttaaaacc actctacaaa aaagaattga tcaagattct ttatcgaatg
    31141 aataatatga atgatgagta ggaatgggga agagagaatg aaatatccgt tgatatggtt
    31201 agaaaaagat gttccgaaag aagagaccac tagaaaattt cctcacactt taagcctggg
    31261 taagttggga aaaggaaaat cttttaacca agtaaagaat caaacaagaa gaggtgactg
    31321 tacatgttag aagcaattaa aacagctttt tcaccacaaa atgatcaaaa ggtacttgat
    31381 ccattaaagc aactaggaaa tcgggaaata gaaattttaa aatccaaagg gtatgattta
    31441 gactttttaa aacaagtgat gccacaaggt ggattaaatt tcgatgaaga gtatgtgacc
    31501 tatggaaatg gttattcacg atgtgtgaca gtttatcact acacaaaaaa tcctacgctt
    31561 ttttggttgg ccaatctcat gaacaatcct catacagtgg caacactaga tgttagcaca
    31621 gatgaaaagc aaaaagtgat tgatcaaatc aatcgtgcct tagatgaatt aaatgatcgg
    31681 tcagataatg aacgaaaagc gactgaccga aataaaagcg cggaagaata cctagaacta
    31741 gcggaatatg cccgaaaatt gacttctaat ggggaaattt ctaaacaagt caaagtgaga
    31801 gtacatgttt acggaaacac gattcaagaa gtagatgaac gagcacagga actgatcgaa
    31861 aatctcaaag ggatggatta tcgtgcagtg acctatctgc acaaaacgaa aagagactgg
    31921 caatcgatgt tcaccatgtt cgatgaacaa gctgaatggt ttggaaatat caaagggcaa
    31981 tcactaccat cgctaaacat tggcggaggt ttcccgttcc accaccaaac gctaaaagat
    32041 ccaggtggaa cacaatatgg ggaaaccatg acaggcggcc cgtttgtttg gaatgccacg
    32101 tataaaaata gtgtgcggtt gtctaccaat accttgcttc taggaatgat gggagctggt
    32161 aaatcgaccg ttcttaaaat gatcgcggaa gcccatttag ctgcaggaga ctttatttgg
    32221 ggctttgaaa agggaaaaga ctttattccc tttttaaagg aatataacgg cattatggtg
    32281 cgtttagacg gatctgacgg gatgatcaat cctttagaaa tatttgccac acgtacgtat
    32341 gatgaagctt ccagtttata tgacgatgga tcagtcaaag atttgaagat caatgaagca
    32401 gcgtcctatc aaacgcactt agacaaagtg gtctatcagg tacagttagt gagtcctcag
    32461 ctaaaaggaa cgatgaaagc agaatttaag acctatttaa atcgttttta tgaagagtat
    32521 ggaacagtac cacgcggctt tacttcctca aattcgcgtt caaatactga tacgcaagtc
    32581 acaggtaaag atccagaagc ttatccgacg ttcaaagaat ttttagactt tttaggacaa
    32641 ctggaattac caggtgcttc ccaagagaaa aagaatcgaa aagaagaaat ggaatccatc
    32701 gtagaatcct tatgtgagac gtatggcatg atttttgatg gtcatagtac gattcgacac
    32761 cttgaccaac aacagttggt cttttttgac attgactcta ttacaggctt agatcgaggg
    32821 gtacaacaat gtcaaatgta catggctatg acgttgattt ggaatcaggc attgattcaa
    32881 ggaagaagac aacgacgttt aattaaagaa aaacaaatgg aagaacaaga cttcaaatgc
    32941 ttcttggcga tgattgatga gtgccataat ggtgcgacct gttctgcagt gaaaagctgt
    33001 gggttgcaag tagtctaaaa actattgtaa taactcttat aacgagaagt caaatgagtg
    33061 ggtaacgcca caaagggctt ccactgatac tccgacatgc aacaagtagt ttatgcagac
    33121 caacgttgtg tgaagctcgg tgaagtcggc tgaaggatac cgtaaggtaa aagaaatagt
    33181 gaataccacg aaagttctct agaggtaaag ggtgtatccg ataagtcggg tgtccaaaaa
    33241 aacttaatat ggtgagtatg tacaaacgta ctgacgaact agcgaatgta ctgtccgaaa
    33301 ggcatagctc ctagaaatgg gagagacagt gagcaaaaaa tcactcattg tgctaacttg
    33361 tggttgagta aaagtcgttg ttatgaaaga ccatgctgcg ttacaggcgt aggagaagtt
    33421 agggggcaaa agctagcatc taagttaagg catgtggata gatataaggg aacaggggaa
    33481 gccatcaaca tggagagtgc atactcgatg aagtggtagt aagaaatatg tgaatgacaa
    33541 ataacttact ttagtgatgg tgaaagtaga gtcacgactg atgaaggttc tgtaatggaa
    33601 ctggaggaac aggctcgatt cgtctgtaaa agtcatgaaa cccgttcaac catgggattc
    33661 tcgtatgact aaaaaggtca cgagccaatt ggagcgtgat aaaccatgac aaaagaaaca
    33721 agtccaaaag ataggaagtt gcggcatgca gaatattatg gcatgacgga aatcttcgat
    33781 aagatatact ccaaaagttt gaagggagat aatttcaaga atctaatgca gattatcatt
    33841 tctgataaca acattgtcct agcatatcgt aatatcaaga gaaatcacgg tagtgtgaca
    33901 agaggagaag atggagtaac gattaaagat attgaaaatc tcaaccgtaa tgaattcgta
    33961 gaaattgtta ggaagcgatt cgcacattat aaccctcgga aagtaaggcg tgtagaaatt
    34021 cctaaatata atggtaaatt aagaccgttg ggtattccat caatatggga tagaatcgcg
    34081 cagcaatgca tcttacaagt attagaacca atatgtgaag caaaattcaa taatcacagc
    34141 tatggtttcc gcccaaatag atcagcagaa cacgcaatag cagattgtat ggcccgaatg
    34201 aatcaaagtc acatggaata tgtggtagat gtagatatca aaggtttctt cgacgaagtc
    34261 aatcatacta aactcatgag acaaatctgg tctatgggta tacgagacaa acagcttctc
    34321 ttaatcatta ggaaaatgtt aagagcaccc gtagtacttc caaatgggaa gttgatatac
    34381 ccaacaaaag gaacaccaca aggcggaata cttagcccat tacttgcgaa catcaatctc
    34441 aacgaatttg actggtggat agcaaatcag tgggaggaaa aagatgccaa agagctaaaa
    34501 catcatttta ggaaaaatgg agcttgggat aaaggtaata tctatcacaa gctcagaaag
    34561 agtacaactc taaaagaaat atacctagtg agatacgcag atgattttaa aattttctgt
    34621 agaaattata atgaagcgaa aaaagttttc tatgcaacta aaatgtggtt acaggagcgt
    34681 ctaaagttac caatatctga agaaaagtca aaaatcacaa atctttcaaa agaagaaagt
    34741 gaatttttag gctttacgat gaaattagtg accaaaggta acaaaaaggt tgttaatacg
    34801 catataggta caaaagcaca aagcatgatt aaagtgaaac taaaaaaaca aatcaaacga
    34861 attcaaaaaa gtcctaatag caaagatacc tttatctata ttggagtcta taacagtatg
    34921 gttattggga ttcataatta cttcaaaatt gcgactcatt gtagtgtagc aatgcgaaaa
    34981 attgcaagag aactcagacc aagttttgaa atacgactac gagaacaagg aatctcaaaa
    35041 gaaggacaat acggaaagta cgaaggatac aagccttacc tacggtcagg acaaatacga
    35101 tatataagag ggtttccaat attaccagta gggtatattc aacacagaca tccgatgtgt
    35161 aaaaaaagaa atattaataa atacaccgaa gaaggtaggg aagccattca taagaagcaa
    35221 caaaccgtag aagaatggaa gatatcgtgg ttgtgtagca atccagtgct tagtaagaga
    35281 gcaacgattg aatttgcgga caatcgaatt tcaaaattca tcgctcaaaa gggaagatgt
    35341 gcagtaacag gtgaggagct tatcttatct gaaatgcatt gtcatcatat tatcccttat
    35401 catgaaagca aaagtgatag ctatgaaaac ctagtgattg ttactgagga ggttcatcgg
    35461 gtaatacacg ctacacaaag tgaaacgatt gaggaacttc taaaatatct aaaattaaat
    35521 ccaaaacaaa aagaaaaact caatgagttg agattaaaag ttggtaacga agaaatatct
    35581 taataaatat ttgtaggacg ggaaaacaga atgtctttta tagacgaggg aacgccgtat
    35641 gcggtgaaag tcgcacgtac ggtgtggact gggggaaaag acggagataa tatcaaactc
    35701 ttacctatca gtatcgatta atccagattt tattgaaacg gtaaattatg tcacaaactt
    35761 tcaacgagaa atgcgtaaag tagaagcaat gactgtttta gctacacaat ccccacaaga
    35821 aatggtgcca gaaaatatgt cttctgataa cttctcgaaa ctgaagaaag tctttgaatt
    35881 ttcttctacg aagatcttta tgcgtatgga tgaatctatt ttacgtcata tagaaggatt
    35941 agttggtaaa tcaatgacaa actcagaatt agaatccatt cctcaacaaa atcaaggaga
    36001 cgctgtgatc aattttggct caaaagaaac cattcgtgtt cattttagtc cgaacaaacg
    36061 tcaattaaaa ttgtttgatg gaggaaaata atggaaaacc aaaatgaaag tttaatcaag
    36121 cagtatgtta agcgtcgtgc aaagcgacgc ttatttttgt ggttgtttgg tacttctgca
    36181 ggtttgatta ctattttgat tactgtgttc gtgacccttt ttctaatact tgcggcgggt
    36241 tcgattgata attctgattc agattcaagt agtggtggcg aagcttttac aggagaatat
    36301 tcggaaggct taccgattta taaagaaatc aaaggaagag gccctttttc tgatgagatt
    36361 gcgcaatatg ctgtaggtgc agcagtgaaa tataaattat taccaagtgt gatcctttcg
    36421 caatacggtt atgaatcagc gtttggtacg tcggcgtccg caagaaatga tctcaactat
    36481 tttgggatta cttggtttga tggttgtctg tttcctaaag gaactgcgcg aggaatcggt
    36541 ggtattgaag gtggctggta catgaagttt cccaactcaa aagcagcctt ctcctattac
    36601 ggctttatgg tagccacaca atccaatttt aatgcatgtg taggaaataa aagccctggc
    36661 gcaagcttat tgatcttagg acgaggtggt tatgccgctg caggaattac tgaagatagt
    36721 ccgtattata caggttgtat gtccattatc acttctaata aattaaccga atatgatgaa
    36781 ttcgccatca aacattgggg tgaaggtggc aataacaacg gcacgatcac tggtgaatgg
    36841 acgaatccat tccctggcag cagtttagat aaaagttcct tcagtggtgg tcaattattt
    36901 ggaacaaatc caggcggtga attccgtccg aatggcttcc atgatggatt agactttggt
    36961 tcagtcgatc atccaggaag tgaaattcac gcggtgcatg gaggaaaagt cgtgtacgtt
    37021 ggcaatcctg gtatttcagg tttaggtgca tgtgtgatcg tgattaatta cgacggtttg
    37081 aatatggtat atcaagaatt tgcgaatagt acaggaaatt ctcgtgtgaa ggttggcgat
    37141 caagtgaaag ttggtcaagt aatcgggata cgagatacag cacacttgca tttaggtttc
    37201 actcgaatgg attggcgtca agcacaagga cacgcattca cagacgatgg tacatggatt
    37261 gatccattac catctttgaa tagcagcaaa aaatagatca ggagaaaaaa tatggaaaat
    37321 aaaactttaa aaatcgtctt aacagctgca attagcgtta gtttaatcgg caatatcgcg
    37381 ttgttttggc agctgaaaga agaacaagag acaaatacct ttaaaattga agaagtggct
    37441 aaaaacgcgt ctgagaagct caaaaaaaat tcctctgagg cacaggcgaa gatcgacaag
    37501 ttaaatcaaa ccatcaatga gaaaaaccaa gaaatcgatc agctgaagca acaagatggc
    37561 acaaaagcaa aagaggaagt aactgaagca caaagaaaga cggcagaaga gttcggtcaa
    37621 ttggccattg ataaatcatt aagtagaaat gaattaacgg aaaaactaaa agatgtcgca
    37681 acccaagaag tgatcgacaa attaagtcct gcagacgatg atcaccaaca tgatgattac
    37741 ggaagttact cctttacatt aggtgacgtg caaacttatg ctcaaacaag cagtgtaaaa
    37801 gaggaacaaa attttgtcgt atttgttgat tatacaatcg gcaatccgca attcaaagat
    37861 gtcaaaccac aaaaaataaa aggtggatta actgtcactg aaaaacaagt agatggtcaa
    37921 tggaaagtca tagactttag ttatttcact cgttaggagg aagaaaatga gtaagaaaaa
    37981 aggagaaaga caacgtttca aaaaacgaaa aagttatctt caatggctgg gaatctttat
    38041 gattctcggc tttttgattc ttgctagtcc gatttatacg aatcagaagg tagatatacc
    38101 agatgaggta agcacgaacg cctttttaaa cacgaaagag ctgacaatgg tttcaaaaga
    38161 aaaaggagcg aaccagcaat tagtttttga atttgcgatc gatgatgaag atcaaagctt
    38221 gttaaaagaa ctggctaatc ttaattatcg cgtagaagta aagacagcta aaggggatta
    38281 tcaagcaata cgagccaaag tgatcaaggt gtctgatgat tattttgcag tgaagctaac
    38341 gcatgtacca gaagaatata tcgccatgcg tttaaccatt attcctgaaa aaattgatcc
    38401 aaaagtggat atgcaagaac cacaagatct gatttattac gtgcacgaag ataaggttaa
    38461 agatcaagtg aaagatgaag attatgaaca acacgcgatc aattacaaag tgaaaggata
    38521 caagaaagaa caaaaagcag ctcaaaaaca aatggaatct ttccaagcaa ccattgattt
    38581 gaatgaagaa ttagtgaaga agctaaaaga tcaattgcct tatcaagtcg cagatgatca
    38641 ggaaaatact gaaaacaaga ttaatagcta ccagcaagaa attgaaacat cgaaaacgca
    38701 actgaaagat caagaagaga tcattcaaaa acttcaagaa aaaattgatc gtatgacaaa
    38761 agaaaagatt tagaaggaca ggtggagtga aaaaatgaag cgaacaaact tggctgacaa
    38821 agatactttc gctgagcaga aagtattgat taaagcctat ctcaaagttg taaaagctaa
    38881 agaaatatgt cgagaagtga atttatctaa cacaacaata tctgagttga agaatggtcg
    38941 aaagaattta gatactttaa aattcagatc atttgaagct ctatatgtag ctgctaaaaa
    39001 atattttaca gctgataaca aataaaaaac aggagtattt tatgtgaaaa aagtatataa
    39061 aaaatgctta tgaatcagct atatcacctt aaccatttgt taatgagatg ggagaaaaca
    39121 ttaaccacga ttctaacgca aacatcaagc acataaaaca tttaacactc ctcctttctg
    39181 gctgaagatt tcaaccaaac aggaagacag cgtatcaatt atagcataca ctttttctta
    39241 aattcatttt tcatatgaca aaatatttcc ttctaatcga caaagttaga aggatttttt
    39301 attgtctaaa tacacaaata accttaattt ttaaagagca taaggaaacg tgatatcact
    39361 ttctcacgaa aggtgttagg taggctgtgc ctaccacgtt tctaagaaag ataaatgata
    39421 tcaaaatttt ggatttgtgt gtagatttgt gggtaggatg aaagcgaatg tgggcagtaa
    39481 aataagcgtt tgtgtgtagc aaaatcaaaa aatgtgtagg gatatgtgta gctacacata
    39541 tccctacaca taataaattt ggaggaaaat atggacttat taattagaaa tattgaagaa
    39601 aagtatatta ataaaattga caaacgttgt gaagaactta cggtcaagac tggcaaaaaa
    39661 tggagtcgaa atcaatacct aaaagttttg atcgaaaatg attttgatca cgctcttctg
    39721 aattataaaa aagaccaatt tgatcggttg ttagaaaaat ttgtggatat tcaaacttat
    39781 aatacgaaaa ctttagaaga atatattgca acaaataatc aattaattgg tttgttaatt
    39841 gaataataaa aatagtattg tgaatttata aaaggaggaa atcaattttg gcaaaagcaa
    39901 caagaaaaca tgtatatctt tacgatatgc atatcgaagt acttgatgaa ataatttcta
    39961 ctcatgaaga tatatctaat tatagtgaag cagtcagaca tttgtgtatg atgtatgatc
    40021 caaaaatcga agaaaaaata aatccaattc aaattaaatt gaatgcaatg ggaaaagaaa
    40081 tttctatttt aaccgaaatg gtttcagagt ttgcggatct tcatttgaaa gatacaggaa
    40141 tactaattgg tacaaattca actgtttatc aagaagcaga agaacgtgtg gaaggaaaaa
    40201 ttaaatccaa tcaaaccaaa aaatattctt ctaagttaaa gaaaccagtg aatgaatctg
    40261 ttcataccag agtagatcca tttgatccaa cgaagattct aaaaagataa aagtagaagg
    40321 agaacgtgat gaataaatcg cctgcagtta ttcttacttg tcaatttacc ttgcccaata
    40381 aaaaatcttt ttcaacatac attgattata tgacaagaga aaaagcactg gaagaaatgg
    40441 aacgacgtac gcccgaagaa gaacaggaac tgcaacgaat caagaatgct ttagaggatt
    40501 tttatattcc tgaaggagaa actttttcgg aaagtaagac ggataaagaa ttcagtgaaa
    40561 cgtcgaatga agctcaatcg ttgatggaac atggaatcaa ttttgacaag ttagaggaac
    40621 aagattttac caaatatctt tcttatatga cccgtcacta tgcgttagaa caaaagaaag
    40681 aactgacgca aagggaacaa aaagaatacc aacggttgaa ccaagcaatg aaaaaatatc
    40741 aaacagagcc acataaaaaa gcttcaggaa atcttcctgg agttttttct atggcttcag
    40801 acgaagtgaa aggaagtgat ctgaaggaga tcaaacaaat cttccaaaga ggacaacaaa
    40861 aaggctcaat catttatcaa gatgttatct ctcacgacaa ttcgtatctt gaaaaaatgg
    40921 gcttgtacga tcccaaaaca gataccttag atgaagaagg tttgaaagca gctggaagaa
    40981 aaatgatgga gacattattc gagaaagaac aattgaatga aacaggttac tggatggcaa
    41041 cgattcaccg taacactaag catatccata ttcattttgc agttgttgaa aaagaaaata
    41101 cgcgtaaacc gtatactgag attgaaaatg gtgtgagtta tatcgtaccg aaggggaaga
    41161 gaagacaagc aacattagac gcaatgaaaa ccaattatgt acatgagtta gaacgtttct
    41221 cttatgaaaa ggatcgaatg atcggtatgg agaaacgaaa tttattgaca cgaaaaagtg
    41281 atttgcgtaa caccttaaca aaagtagtaa aagaaccagc acgttacgat cgacacgcca
    41341 tgaacttatt aaatgaagta tataaaaccc tacctgaaaa acgttcggaa tggaattatg
    41401 gagatgaaaa tcgaaccaag ctttcaccat ttacaagggg aaaacttgat gagttaacca
    41461 aatatgtttt aacaaaagaa cctggatatc aagaatatat acagatttca aaagcattga
    41521 aagaagaagc caaaagcctt tatggggaaa gcaaaagaga aacaaagaat gcagaaaaaa
    41581 acgccctctt tgatttaaaa aagcgcacag gaaatgcgat tttaacagaa ctgaagagac
    41641 aggatagtca aataaaacca ttaatagaaa gtgtcaatca gatgcaatct atttacaatg
    41701 aacgatcctt tcgaacactc aaacagttgc caacaaatga atacaagtat agttatcaag
    41761 aattcgtaaa gcgtaggaaa caattccaac aaagagttgt cacgcagcga agcttgcgtc
    41821 aattaaatcg aacaattaat gcacatgaag aaaaatacca cgcaagtaaa gcatatgaag
    41881 agcaacagcg aagaatccaa atggaacaag aaagacaata ggaggaagag aaatgaaaca
    41941 atatttagat caatggaaag tcatagaagg atcactaaaa gaagaacgaa tcgaacaact
    42001 tcctgattgt ttagaaaaag agcatttgtt tcagataagc gaaatgttga gaaacgaaca
    42061 gtttgatcca aatcaatttt tagttgttga gtacccagct actggtgtgt attgttgtaa
    42121 tcatgtgaag ggtgaaaaat attttattat tcaagaatac gaaggtaagt tagcgcctta
    42181 ttatactact tgggaaataa atgaagaggg aatcaataat ttcccatgtg aaagcattga
    42241 agagtctatt tctctcacgg aatgttaaat aaatagagac gtaaaagagt cctgaacgtg
    42301 attgtccagg actctttttc aatgaattgt tttccgccaa ttcactgagt ggtgcgattc
    42361 aattttatta tatcaaaaga aagtgagatt ccaaagtgaa gggaggaaga agaaatgact
    42421 cagacaacga ttggtgttgt ggttgaaaaa agcagggata atctcgtttt tgtgacagaa
    42481 attcaaacag gtagagcttt tgtagtcaca gacaaagctg caaaagcgta tcaaaatggc
    42541 aatattttaa cgttaaatct gactacgaag atgttcgttg atgcagtaga aaattatcca
    42601 tttgtttaga caaacgatat tttacaagga ggaaacggac atggcagaag aaaaagaacc
    42661 actagataat agtcgtttgg gaaagtccaa aagaaaatta gtacggttgc aaaacgaatt
    42721 aaataatcaa tttcaaaagc tatttgatca ccaaaaattg acaaatgggc aaccaatgaa
    42781 tgacaaacga aatggtcgtt catggtttaa ccagcaagaa aaaatagaaa ataaaataca
    42841 aagtttgaga gaagagatca agcaacaaga aaaacaggta gaaaaacttg aaagacaaga
    42901 agagctaaag gaaatgggtt ataacaagta cggtggcctg gacatgacga tcgaaaatat
    42961 tccaagaatc aaagaagaaa tcgaacgctt tgaaaaaggt gaatcgactt tttcagctgc
    43021 cacgatccga aaataccaac gaaaattgga aacattagaa cagctgaaag aaaaatcaga
    43081 gaaaggaaaa gaaaatcttc ttcctgaagt acaagcgatc attgacagcg gacgagtgac
    43141 gcaatggaaa aagaatccaa ctatctattt tctgaaaggc tatcgaaaag tcgctttaga
    43201 actcaatgaa aacgggggat ttgaggaatc taaaaaatac caagccacgt cggaagaaga
    43261 aaaggcagct gttcgtgaat tacttgaaga agctacacct actgattctg tgaaggagaa
    43321 agaaaccgat catttctatc gagtagaatt caacgaaaat gatccagcaa aagggttgaa
    43381 aagttatggt ggggagatcg taacactaga attgatcgat caactcaaaa cactggataa
    43441 ccaatacgcc gcagaagcag gctattataa attctatttt gaagaagtga agaatggaga
    43501 agtagtcgat cagatacgaa tggatctagg ggatggcgtc aatagtaatc accccatcta
    43561 tttagagtta gctagattgt gcgaacaatc acctgaaaag gaacaagaac aaacagtcaa
    43621 aaatgaacct atttcaaaag tacaaaacga gattaaagag acaaaaacaa aacaaaaggg
    43681 ttatcaaaaa cgaacggcag aagagattaa gcaagaagtc aaatcacttt cccaacaggc
    43741 gcttgatgcg gtgaaaaagc atactcattc acctgaagac gtcaaagaac ttttgaattt
    43801 tatgtctcgt tttccagaac gatcctttag aaatcaatta ttgatcgagg aacaatttcc
    43861 aggcgcaacg gcttgtttag gtcgtgccgc gttgaaaaaa gaaggaatct atatcaaaaa
    43921 aggagaacaa gggaacaaga tctttgtcag aaaaacggtc aaaggatttt atgagaaagg
    43981 acgtggcttt gttcgagaaa cagaggctac accagaagat aaaaaacgaa tcgaaagtgg
    44041 tcaaatcgaa gtgatcaaaa aaccttacta cacgattgaa aaagtgtttg atatcacaca
    44101 aacacaattg aaacctgaag actatccgaa aatcttcccg aaccgcgtct ttgattttca
    44161 attggatcaa acagggcaga cagaacttca agttgggatt caagcggtag ccaaaaatat
    44221 tggaattcaa attcgagata tgacagaaag tgaagtctat caaagagaat taggacaagc
    44281 acgtggggcg tacgttcgta acgaatttac tggcgaagaa gaaatcgtca tgaatactcg
    44341 aaatactcct acgcagcatt tagccacaag tattcacgaa ttagcccatg ctagaatgca
    44401 caaattttca gaattagata ctgcaacaaa agaactacag gcagaaatga cctcctatat
    44461 tgtgtgcaag cattttggga tggacacctc ggagaaagct attccttata ttgcgacatg
    44521 gacgaagaat agtcagacgt tggatgataa ggaagctgcg gaacgtggga aaatcatgaa
    44581 tgatgtcagt cgtgtcgcaa atgaattcat tcaaaccatt tctaatgaaa tcaatcaata
    44641 cagagaaaga gaaccagaga tccagccagc agaagtgaag caggagcata aaaatactgt
    44701 agaaacggca gaacaaaaga atattgtgcc cgttggctca ctttggatcg acaagaaaga
    44761 cgggaaagtc ctggaagaag acacgggccg aacgttacat ttgaaggatg cggcgtttat
    44821 tgaagatccg cagcataatc aagtgatttt aaaaggaaaa agttatggaa aagagatcca
    44881 aacggcgtta ccttcagaag aatttgcgct aggaaatcca ttccgatttt cacttgagac
    44941 agtgtcagaa gtggcaaaac gaaaaaatga aatctattat gaacaacaat tgtcacaaaa
    45001 agaacgcgta taaaacaagc aagaaagact atctgaaaaa tggatagtct tttttctttt
    45061 gggaggtttg aaaatgacag agaaaaaaat gagtctcatt gatcgatgca agcaaatgga
    45121 tattgtggat tttgcacgaa acaatggttt agcggtggcc aataaaggac gagactatcg
    45181 cttagaagac catgattcat ttgtttttga tcgaagaaaa caacgttttt attggaacag
    45241 tcaaaatatt agtggcgaca ttattgaatt agctaaactt tttttcatag acaaagagat
    45301 ccaagaccct aagcaacaat ttaaagcagc cactgatttt attctaaaga atgaagacaa
    45361 aacagaacga gtggaaaatc ttcattttga gacagaaaag tacaaagatc accccgttga
    45421 ttatcaacca ctcacagaaa aaggaaggaa ttatctgaag gaagaacgaa aactgcccga
    45481 ttggttgatt gattatgcag aaaaagaagg attgattgcc gaactaaagc caaaacatga
    45541 acggcaaaat ttcttagttc gagacgatcg tttggatcat gcggtcgcct ttttatggaa
    45601 agatccacag acaaaagaga cagtaggggc gagttatcaa ggaacgttca ttgattatga
    45661 acgttttggt gagagaggca catataagca tatagataaa aattcgacag cgaatcatgg
    45721 ctttaaccta aagattggtg atcctaaaca gttaaaattt tttgagagta gtattgattt
    45781 acttagctac gctgcactga atcgtgatca gttaaacgat acgtggttag tctctatgga
    45841 agggttaaaa caccatgtga tcagtcatta ttttggtgag gcagtatctg aattgagaaa
    45901 gaaacaagcc tttcctcaat ccatcgagat ttgtgtggat aatgaccgtg caggacatat
    45961 tttctacgaa aaagaacaat taatgggcgc agttgatcca tttacgaatc agaaagtacg
    46021 ttgtgaacga ggaatcgcta atgattggca agtgccaaga gaatacaaag tcatttatga
    46081 agaagtcgca aaagaagaaa aggtcacacc agaagctatt atggccatac acaagacaga
    46141 aaacaatctg caattaacga accaactggt ttccgctcac aaagtcaatg cgtcttttgg
    46201 tcagcagctt tctgttaacg attcaataga agtcattagt ttgaaagata tttgtagaga
    46261 agtcgcaaaa gaattaaaag attgtgaacg ctcgaatggt acgtatgatt ttgatcgttt
    46321 ttatcaagga aaaggggata ttaattctca gattcttttc tcttataaag cagaacaata
    46381 ctacaaaggc tataaaaatc atgaacatga atttgtacct gaagtgaaaa aggattggaa
    46441 cgatcaattg aagcatgaga tccatcaaca ggaaattaga aagcaaaaac gtgcgatgtt
    46501 gtttcaacaa ggcagacaac aagaaaggga gtgagatcgt cacgatgaaa actgtcattt
    46561 tagcagaaaa accgtcacaa gcgaaggcct atgccgatag cttttctaaa gccacccgaa
    46621 aagacgggta ttttgaaatc caagatcgat tgttttcggg tgaaactgtg atcacgtatg
    46681 gttttggtca tttagtcgag ttagattcgc ccgatatgta cgatgaaaat tggaaacaat
    46741 ggtcattaga gcatttgcct attttcccta cacattatca ctatcatgtt cctaaagata
    46801 agaaaaagca attcaacgtg gtgaaacagc aacttcaatc ggccgacacc attattattg
    46861 cgacagatag cgatcgtgaa ggggaactga tcgcttggac gatcattcaa caagcaggcg
    46921 ctgatcaagg aaaaaccttt aaaagacttt ggatcaactc cttagaaaaa gaagccattt
    46981 atcagggatt ccagcaatta cgagacgcag aagagaccta tcccaaattt gaagaagcac
    47041 aagcacgcca gatcgctgat tggttgatcg gcatgaacgg cagcccactg tatagtttac
    47101 tcttgcagca aaagggcata ccaggaagtt tttccttagg cagagtccaa accccaacgc
    47161 tttacatgat ttatcagctg caggaaaaga ttagaaactt ccaaaaagag ccttattttg
    47221 aagggaaagc ccaagtaacc gctcaaaatg gcatatttga tgcgaagctt gatcccaatg
    47281 aaacccaagc gacgcaagaa gcatttgaag cctatttaaa agaaaaaggt gttcaagtag
    47341 gaaagcagcc aggcacgatt cttgaagtcg aaaccgagaa aaaaagcgcg gcaagtccac
    47401 gtcttttttc tctatccagc cttcagtcta aaatgaatca gctcatgaaa gctagtgcca
    47461 aagatacttt ggaagccatg caagggttgt atgaagggaa atatctaagc tatccacgaa
    47521 cagacacccc ttatattaca gaaggagagc atgcgtatct gttggatcat ttagatgaat
    47581 acaagcattt tttaaaggct gaatcattcc ctactcctat tcatacaccg aatagtcggt
    47641 atgtgaataa taagaaagtc caggaacatt acgcgatcat tcctacaaaa acagttatga
    47701 cagaagcaac gtatgaaaag ctgacacctt tacaacaagc gatttatgat caagttttaa
    47761 agacgacggt ggccatgttt gcggaaaaat atacctatga agaaactacg attttgacac
    47821 aagtccagca gcttcagcta aaggcagtcg gaaaagtacc agtagatcta ggttggaaaa
    47881 agctatttgg caaagagagc gacagaaaag agaaggaaga agaaccgcta cttcctaaag
    47941 taacaaaagg agaaacggtg acggtagatc tacaaatctt tgaaaaagaa accaagccac
    48001 cacaacctta cacggaaggt acactaatca ccgccatgaa gacagctggt aaaaccgtgg
    48061 atagtgaaga agcacaatcc atattgaaag aagtggaggg aattggtaca gaagcgacac
    48121 gagcaaatat tattgaaacc ttgaagcaaa aggaatatat caaggtagag aaaaataaac
    48181 ttgtggtgac gaataaagga attttgcttt gtcaggctgt tgaaaaagaa ccgctgttaa
    48241 caagtgccga aatgaccgcc aaatgggaaa gctatcttac aaagattggt gagcaaaaag
    48301 ggacacaagc tacttttcta gcaaatatcc aaaaatttgt ttcccacttg ttggaagtcg
    48361 tcccaggaca aatccaagcc actgattttg gagcaacgtt acaagaggtg aaagtagcca
    48421 gtgaaaagca agaagcggcg cgtcatttag gatcttgtcc aaagtgccag gaaaaagaag
    48481 tcatacttta tcagaaggtg gcgacttgca cgtctgaagc ctgtgatttt aaattgtggg
    48541 taacgattgc caaaaagaaa ctcacagcga cacaactgaa agagatcatt cagaacggcc
    48601 gaacaagtca accagtcaga ggactaaaag gtcagaaagg ttcgtttgaa gcaacgatcg
    48661 ttttaaaaga agactttaca acaggatttg agttttctga aaagaagaag accacctaca
    48721 aaagaaaagt gagacgtaaa acgagttaga attgacggag ggaaaaacga tgagaaatac
    48781 aacgcataaa gaacaagaaa tcgaaaatca aaaagccaaa atacgttcag agcaggagaa
    48841 aatgcgtgcc agcaaacgaa gactacagca attgaagaat caacaacgga ttcaaaaaga
    48901 acttgaatta gatcgataaa tcctcctgtt gttaatatta aactaacatg ttatagttat
    48961 gttagtttaa tattaacatt cgagagggaa agcgatgaaa gataaagtca agtgcatttt
    49021 tgagaaatac aatggtaatc tatccttgaa ggatgctaga aatgaagggt tatcacctat
    49081 gacgttagat cgtttagccg aaaaggacaa aatagaaaaa atagcatcag gtttttatac
    49141 cttaaaagat agttttgtgg atgaattata tctcgctcaa agtatctata ctagaggaat
    49201 cttctctcac gagacagcgc ttgatctttt tcaagtagga acatatatcc ctaaaaaaat
    49261 taatatgatg tttcctaaag gatacaatgt ttcgaaagag aatttagatc agtatgccat
    49321 tcaaccgcat tacacgaata aagaaaactt tgaactggga atcacagagg cagaaagctt
    49381 ttacggcaat aaaattttcg tctatgattt agagcgaacg ttatgtgata tgtggaatcc
    49441 cagatataaa gcaagcgtag aagtaaaaca agaagcatta aaagaatata tgacaagtac
    49501 cagcagaaat acaaataagc taagaagata catgaatatt ttaaaatcac caaaagaaat
    49561 gactttgtat atgttgccac tttattgaga ggagtaaagg tgaatgacac cgacacaatt
    49621 taaagcgaaa acaagaaatg ttgcagctga gaaacattta aacccacaaa ttgttcaaag
    49681 atattatatg atggaaaaat tattagaatg tattgttgaa tcgccttatc atgatgattt
    49741 tgtattaaaa gggggatttc tgatcggatc aaaatacggg ttagaaaacc gttcaaccgt
    49801 tgatattgat acgacttatc gaaattcgaa actaacaaaa gaaaaattag aaactgtttt
    49861 ttctgaatta acagctgctc ctacaaaaga tggcattcgg tttgaattaa agggcttaac
    49921 agagacgagg gaagccgatt attacccagg ttttcaagca aagtttattg cttttcttga
    49981 aaatgcacgt gtacctttta aattagatat tacttcaggt gattctatta ttccagcagc
    50041 attgatatat gaacataaat tgatgtttga agataaaaca attcatattc cagcttatcc
    50101 tacggaacaa attttagctg aaaaattaca tgccacgttt agtttcggaa tagataattc
    50161 acgtatgaaa gatttctatg atctgtatat gatccctaaa ctagaacgta tcgatgagat
    50221 aaatttgtat aagagtgttc aaggaacatt taaggaaaga aataatcaat cagtgtttaa
    50281 gaatttgtat aatcaggaaa tgcctcaatt gatgaagaat gagggattga gggagaaatg
    50341 gaaaagatat cagcaagaaa actattttgc caaagatatt tctttcgaat ctaccttaac
    50401 ttctgttgat tcgctgatgc aatcaattgt cgagcaagag gaagtagaac gaaaacaaaa
    50461 ttttaagaga tcacaacaaa tgaatcaaga aatggagaga taaagatgat caataatgta
    50521 actttagtag gtcgattaac caaagatccc gatttacgtt acaccgcaag tggcactgca
    50581 gtgaccactt ttaccttagc cgttaaccgt aattttacta atcaaagtgg caatcgagaa
    50641 gctgacttta tcaattgtgt gatttggcgc aaaccagctg aaacgatagc gacattagct
    50701 aaaaaaggca gcttgatcgg cgtcgtcgga cggattcaaa cgcggactta tgacaaccag
    50761 caaggacagc gtgtctatgt gactgaagtt gtggccgata atttccaact attagaaagt
    50821 aaagcagcga cagaaagccg tatgcacgct gatcaatcgt ccagcagtcc aagccctacc
    50881 acctttgaac aacgggatac agcgacgcct aacaacaatg gattgaacgc ttcacagaat
    50941 ccatttggtg gacaatcaat cgatattagc gatgatgatc taccgttcta agtagcattt
    51001 tctattggtt gcatttgcta cggtttatgt tataatttag acaacaaaaa gaattttcaa
    51061 tctataacca aaaaccacta gctggcgggc tagtggcttt cttttacgtt tctattataa
    51121 gaattaacgg gtaggcttac tgtctttctt ggcaaattta caatcaagcc atttgcagat
    51181 atagtgcgcg gctacttctg ccatgattgc aaaaacaaaa tcaaaaagaa ttttcaaacc
    51241 tataacctcc tccccttgcc agattaggcc ggggtagcag acagcaagac tattatagca
    51301 taattgaaat atccaaatga ttggattttt gctataattt tagcgaggtg attgtgatga
    51361 acaaatatgt tggtttgctt gataaaatcc gagtaataaa aacgcaaccg ttattggttc
    51421 gctttacttt acaaacgatt catgaatcga ttaattgtgt agttgcagat attgaaatta
    51481 tcgataaatt gctaattatg gatgatggaa aatacaatat tgccgtcaca ggtcacttca
    51541 ataaacgaaa tcagctagtt attgctagca tgtatgttag aaatcccgat cattttacgc
    51601 gatcgatggg catataaata aaagaagagt tgtagtccta aatgaggatt gcagctcttt
    51661 ttgttttaca tagaaacagg aaaagacctt tttaggaaga cacaagtgcc ttctcaattg
    51721 aaaaaccttt ctctcactcc aaccgccacc gccgttcgag aagaaaggaa gtgaacgctg
    51781 cacgttcact aagatatggt gtcttgcaaa gcaagacaaa atagacaaaa cttcctctca
    51841 ccaaaaggtt
//
LOCUS       DACGDM010000012        51302 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.012, whole genome shotgun sequence.
ACCESSION   DACGDM010000012 DACGDM010000000
VERSION     DACGDM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.012"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            330..1175
                     /locus_tag="IXR05_000767"
     CDS             330..1175
                     /locus_tag="IXR05_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4259308.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="IXR05_000768"
     CDS             1456..2676
                     /locus_tag="IXR05_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAQ4259309.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="IXR05_000769"
     CDS             2673..5393
                     /locus_tag="IXR05_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4259310.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="IXR05_000770"
     CDS             5377..6321
                     /locus_tag="IXR05_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4259311.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="IXR05_000771"
     CDS             complement(6390..7400)
                     /locus_tag="IXR05_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4259312.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="IXR05_000772"
     CDS             complement(7580..7924)
                     /locus_tag="IXR05_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4259313.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="IXR05_000773"
     CDS             complement(7917..8351)
                     /locus_tag="IXR05_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAQ4259314.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="IXR05_000774"
     CDS             8489..9226
                     /locus_tag="IXR05_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259315.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="IXR05_000775"
     CDS             9219..10430
                     /locus_tag="IXR05_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259316.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10637..11416
                     /locus_tag="IXR05_000776"
     CDS             10637..11416
                     /locus_tag="IXR05_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAQ4259317.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="IXR05_000777"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="IXR05_000777"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAQ4259318.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="IXR05_000778"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="IXR05_000778"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAQ4259319.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="cpaF"
                     /locus_tag="IXR05_000779"
     CDS             14132..15061
                     /gene="cpaF"
                     /locus_tag="IXR05_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAQ4259320.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGTVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="IXR05_000780"
     CDS             15018..16067
                     /locus_tag="IXR05_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAQ4259321.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="IXR05_000781"
     CDS             16064..16342
                     /locus_tag="IXR05_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAQ4259322.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="IXR05_000782"
     CDS             16317..16787
                     /locus_tag="IXR05_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAQ4259323.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="IXR05_000783"
     CDS             16804..17106
                     /locus_tag="IXR05_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259324.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="IXR05_000784"
     CDS             17123..17494
                     /locus_tag="IXR05_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAQ4259325.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="IXR05_000785"
     CDS             17466..17825
                     /locus_tag="IXR05_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259326.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="IXR05_000786"
     CDS             17997..19004
                     /locus_tag="IXR05_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4259327.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="IXR05_000787"
     CDS             19029..20213
                     /locus_tag="IXR05_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAQ4259328.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="IXR05_000788"
     CDS             complement(20650..22233)
                     /locus_tag="IXR05_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4259329.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVDINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHCQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="IXR05_000789"
     CDS             complement(22811..22954)
                     /locus_tag="IXR05_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAQ4259330.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23176..23655)
                     /locus_tag="IXR05_000790"
     CDS             complement(23176..23655)
                     /locus_tag="IXR05_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4259331.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23728..24012)
                     /locus_tag="IXR05_000791"
     CDS             complement(23728..24012)
                     /locus_tag="IXR05_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259332.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24090..24284)
                     /gene="ssrS"
                     /locus_tag="IXR05_000792"
     ncRNA           complement(24090..24284)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IXR05_000792"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24356..25642)
                     /locus_tag="IXR05_000793"
     CDS             complement(24356..25642)
                     /locus_tag="IXR05_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAQ4259333.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25780..26451
                     /locus_tag="IXR05_000794"
     CDS             25780..26451
                     /locus_tag="IXR05_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAQ4259334.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26417..26905
                     /locus_tag="IXR05_000795"
     CDS             26417..26905
                     /locus_tag="IXR05_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAQ4259335.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26918..27865
                     /gene="prmA"
                     /locus_tag="IXR05_000796"
     CDS             26918..27865
                     /gene="prmA"
                     /locus_tag="IXR05_000796"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAQ4259336.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27866..28630
                     /locus_tag="IXR05_000797"
     CDS             27866..28630
                     /locus_tag="IXR05_000797"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAQ4259337.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28863..31076
                     /locus_tag="IXR05_000798"
     CDS             28863..31076
                     /locus_tag="IXR05_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAQ4259338.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31087..31533
                     /locus_tag="IXR05_000799"
     CDS             31087..31533
                     /locus_tag="IXR05_000799"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAQ4259339.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31704..32963
                     /locus_tag="IXR05_000800"
     CDS             31704..32963
                     /locus_tag="IXR05_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAQ4259340.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33052..33999)
                     /locus_tag="IXR05_000801"
     CDS             complement(33052..33999)
                     /locus_tag="IXR05_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4259341.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34393..35685
                     /locus_tag="IXR05_000802"
     CDS             34393..35685
                     /locus_tag="IXR05_000802"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAQ4259342.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35700..37469
                     /gene="aspS"
                     /locus_tag="IXR05_000803"
     CDS             35700..37469
                     /gene="aspS"
                     /locus_tag="IXR05_000803"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAQ4259343.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37578..38453
                     /locus_tag="IXR05_000804"
     CDS             37578..38453
                     /locus_tag="IXR05_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4259344.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38719..40602
                     /locus_tag="IXR05_000805"
     CDS             38719..40602
                     /locus_tag="IXR05_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4259345.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40677..40961)
                     /locus_tag="IXR05_000806"
     CDS             complement(40677..40961)
                     /locus_tag="IXR05_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4259346.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40951..41685)
                     /locus_tag="IXR05_000807"
     CDS             complement(40951..41685)
                     /locus_tag="IXR05_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAQ4259347.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41814..42437
                     /locus_tag="IXR05_000808"
     CDS             41814..42437
                     /locus_tag="IXR05_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAQ4259348.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42629..43750
                     /locus_tag="IXR05_000809"
     CDS             42629..43750
                     /locus_tag="IXR05_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAQ4259349.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43757..46885
                     /locus_tag="IXR05_000810"
     CDS             43757..46885
                     /locus_tag="IXR05_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAQ4259350.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANERIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46904..50098
                     /locus_tag="IXR05_000811"
     CDS             46904..50098
                     /locus_tag="IXR05_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4259351.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50244..50951)
                     /locus_tag="IXR05_000812"
     CDS             complement(50244..50951)
                     /locus_tag="IXR05_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4259352.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16795 a         8950 c        10643 g        14914 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc ttgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatctcaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggctt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cgggacagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg aaactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acagtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatat cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccctggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttat
    23041 tttacttgaa ctcattgact gttttccctt tattttaaac attataaaga ccgatgagtg
    23101 cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa aaaaacctgc cgatagttgg
    23161 caggtcgtct acgtgttaag ctttggtgtg gtctttagct ggcaattggt tttctaaatc
    23221 agttcggaca acaagcacat cgcaagctgc gtttctaata acatattcag aaacagaacc
    23281 aataaataaa cgttctacag cattcaatcc tgtggctcct aacataatca aatctacttg
    23341 attatcttct gggatttctc tggcaataat ttgttttggt gagccatatt ctacgacaga
    23401 ggttacatta ttcaagccag ctttcttcgc attgctttca taatctgcca atgtttgctt
    23461 tgccatttca gtagcttgtt ctgcaagcat tccatcaaag gatgaaacgg tttggaaaga
    23521 acgtgtgtca atgacatgtg ctaatagaag ttctccgtta tttcggatag ctacattgac
    23581 cgccttttta aaagctaatt cagcttcatc agaaccatct acggcaacca tgattttttt
    23641 gtattgttgt aacataagca ttcactcctc aagtcaatcg tattgtactc ttttattgta
    23701 gaacacttta gggaaaaaga gaattattta ctgctttggt tcagcaattt tttttgcaaa
    23761 tcggatactg aaggtggcag aaacaataat tacgatcagt aaaaagacca aggcaataaa
    23821 gcgttgattg aaaaaagctg ttaaaatacc cattacgcct aaaacagcat atgcagcacc
    23881 gtaaaattgt aggaatcctt gatttttatc atttttgttg atcaatacaa aaaagatatc
    23941 ctgtttatta aataaataat agctaacgaa taataatact aaagtggcga taatcattaa
    24001 aatcctaatc atgaacaaat cctccaaaat aagcaacaaa tagaaaaagc aatttgccaa
    24061 gagcaaattg ctttattctt taaaagatgg taatctccgt taatgccgtt gtttgtcctg
    24121 tagtattgat cccgcgaatt caagcaggtg ggtcccatgg tcgtagcttc gaactaccaa
    24181 atgataaggc atgttaccag cagtgacaca agacgggtcc caagatatca ataaaaatgt
    24241 tcggtcaaca cacaaagagg acaattcgaa catcacagat ttcccacctc tatagtagca
    24301 tatgaattta aaaagagcaa tgagagagct cgcagaaaca gaaccgtttt cttgtctagt
    24361 tttttggagg atgctttttc cactctttta tacggtaata ctgttgaccc agagcctgtt
    24421 catatttccc tgtatctttt ggctgataat actgagcatt cttcagttta tctggtaaat
    24481 attgctgatt gacccaagcc tgatcaaaat gatgaggata ctgataaccc acgccacggt
    24541 tgagtgattt cgcacctttg taatggctat ctctcaaatg atcaggaaca tctccagctt
    24601 tgccctctcg aatatcagca agtgctgcat ctaatgccat gtaggcagaa ttggattttg
    24661 gcgacaagca aagatcgacg acgacgtctg ctagtgggat acgtgcctca ggcaatccca
    24721 atttttcagc agctaataca gcgttcactg tacgagccgc agcagcagga ttacctaaac
    24781 ctatatcttc ataaccgata accatcagac gccggcaaat acttgccaga tcacctgcct
    24841 caactaaacg ggcgagataa tgaagtgcag catccacatc acttccacga atcgattttt
    24901 gaaaagccga aataacgtca taatgagcat ctccattttt gtcatgggta agagcttttc
    24961 tttggacaca ttcttcaatg atcgacagtg taagatgaat ccttccttct ttatctgaag
    25021 gagtcgatag tgtagccagt tccagcccat tcaatgcact ccgcaaatcg ccgttcgttg
    25081 cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat tgcttgttgt ccaaggccgc
    25141 gttctttatc ccttaaagca tgttcgactg ccaactggat gtcttgttct gttaatggtt
    25201 tgacttcaaa gatctgtgta cggctgcgga tcgctggatt gatggtaata taaggattct
    25261 cagtagtcgc tccgatcaag atgattcggc cactttctaa atgaggaagc agaaaatcct
    25321 gttttgtttt atctaatcgg tgtacttcat ccaataagag gatcactgta ccactcattt
    25381 ttgcttcttc cgctacaact tgtagatcct tttttgaatc tgtagcggcg tttagcatgc
    25441 gaaatgcata attagtagag ccggcgatcg cacttgcgat actcgttttt ccagtaccag
    25501 gaggtccata tagaatcatg gaagagagca tgcgagcatc gaccatgcgg cgtatgattt
    25561 ttccttcccc gactagatgc tgctgaccaa cgacttcatc gatcgttcga ggtctcatgc
    25621 gataagccaa tggctgttgc ataggatttt cctccttctt gtttttacgt cccttaatta
    25681 tatcatattt agcaagatgc ctagaaagaa cagccttctg ttgttttgtt ttcatagctt
    25741 atccaactaa tattgtgtat gataaagtag gtgagaaaaa tgacggataa acaaaagata
    25801 gatgaatttt tttggaataa aacgacgcca gaagtggcac gggatttatt ggggatgtat
    25861 ttggagcatg acacaccaga aggaagatta gctggatata ttgtagacgc ggaagcatac
    25921 ctaggtccag aagacgaggc cgcccatagc tatggtttaa gaagaacacc gcgtgtgcgg
    25981 gcaatgtatg aaaaaccagg tacgatctac ctttacacga tgcatactca tcggattttg
    26041 aacatcatta ctcagccaga agggattcct caaggagtaa tgatacgtgc aatcgaaccc
    26101 gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa aaactggtcc agatatcagc
    26161 aacggtccgg gaaaattagt ggaagcatta gcaattcctc aagaacttta tggtcagtct
    26221 atagcagata gttcgttacg cttagttttt gagaaaaaaa agacaccaaa aaagatcaat
    26281 gctttgccta gaatcggtat cccaaacaaa ggtgtatgga cagaaaagcc gttgcgtttt
    26341 gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa accaaatcga gaaagattgg
    26401 ggttggagga aagaaaatga aaaagaagga tctattaaca tatttagatg aaataattga
    26461 aaaacaagtg acagactatg atgtagcttt agattgggat acaaaaaatc atacgatcga
    26521 gatcgttgtt cgcttgtttg cagaaaataa agcacaattt gagattgatg atgcagaagg
    26581 gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc gtacttcttt ttaatcctca
    26641 gaaatctgtt tttgatgaac gcaattatct agcagtaatc ccttatgaag gaaaaaaagg
    26701 gttggcaaaa tcagtagctg attctttagt ggaatatcta aatgaagtat tagctcaagg
    26761 gcaaagcgat ttgcttgatt ttttggatga agacgatgac gaagctgtat tcgagcttca
    26821 ctgggataat caacaactag cagaattagt agaagtaaaa cagcaaaatg aagcagatac
    26881 ttatttaccg tacccaagtt attaaggagt gacagatatg aaatggaatg aagtaaaagt
    26941 agaaactgaa agtgaagcag tcgaagcagt tgctaatatt ttgatggagg caggggcgag
    27001 tggtgtcgcg attgaagatt ctttagatgt tgaacatttt cagtcggatc aatatggtga
    27061 gattttagat aaaaatgatt ttacatcgct gaaagaaggc gcactagtca tggcttattt
    27121 tccggaaacg actttcttac cggaaatctt gccttttatc aaagatcgta tcacacaatt
    27181 acctgagttt ggtctagcta ttggaaaaaa taaagtaaca gttagtgaag tagaggaaag
    27241 caactgggca acagcctgga agaaatacta tcatccggtg cgtattacgc gaatgctgac
    27301 ggttgcgcca agctgggaaa actaccagac agaagatcct ctagaaaaaa ttatcacact
    27361 agatcctggt atggcatttg gcacaggcac tcatcccacg acttccttga cattgacagc
    27421 actagaaaca gtcttgcgtg gtggtgaaac attgctagat gtgggaactg ggtcgggcgt
    27481 gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc tatgcctttg atttagacga
    27541 agtagccgtt cgttcggcga aagaaaatat ggatatgaat gaaatagcca aagatgtcca
    27601 tgtatcagct aacgatcttt tgacaggaat cgagattgaa agtgatgtaa tcgttgcgaa
    27661 cattttagca gatatcatct tattgatgat cccagatgct tggcgtttac tgaagcaaac
    27721 aggcacgctg atcgtttcag gaatcattga agagaagaag caaatggttc tggatgccat
    27781 gttagaacaa gggtttatcg tggatcaaat tttccagcaa aaagactggt atgcaattat
    27841 tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt ttaaaagaat catatgaatc
    27901 aaaagactat tttgttttag aaggggaaaa ctatcaccac attgtacggg ttatgaggat
    27961 ggaacccgag gatgaagttt ttttggcatt caatgatcaa atagccattg ttgcagaaat
    28021 cacggagatt actgaagagg ctgtttatct gaaagaaatt aaaaaagaag aaaatcaaaa
    28081 ggaactgcca agttcgatta ccatagcgag tggctatcct aaaggggaaa agctggattg
    28141 gatcgttcag aaatccactg aattaggagc gcaagctttt cttggtttcc cggcatcagc
    28201 ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga caacaacggc ttgaaaagat
    28261 tgctcaagag gcagcggaac aatcccatcg gcagatcgtg ccatcagtag agttattgga
    28321 aacgaaacaa gatttatttg agcggctaga tgattatgac gtggtcttgg ttgcttatga
    28381 ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa attcttagtg aaacaaaacc
    28441 agatagtcga atcttagctg tctttggacc agaaggtgga ttatcccgcg atgaagtcga
    28501 ttattttgta gaacacaaag ggatactttg tggattagga ccaagaatcc ttcgtacaga
    28561 aacagcacct ctttatttat taagtgctgc tagctatcaa tgggaattaa tgaatccttc
    28621 tttcagctaa cgttcttcat taataaaaga gtatcgacag aaagaattga aaaaatagtc
    28681 aacaatttgt ataatagaaa caattattta tacaatggat acgaaaaatc gtttgaaaaa
    28741 gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac tgcacggatt ttgggacaat
    28801 tatcaaacag atatttgtcc cgattcccgt tttaccgaaa aaagaaaggg ggatcgattc
    28861 ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat aaagctcgtt agtcaataca
    28921 tgggtcccga acatgtagca tttgttgaga aagcatgcga atacgcgact gctgcacatg
    28981 acggacagtt tagaaaatca ggcgaaccct acattattca tcctatccaa gtcgcaggta
    29041 tattagcaga tttaaaaatg gatccccata cagtggctac aggcttctta catgatgttg
    29101 ttgaagatac agaaatcact ttagaagatc tgagagaaga atttggcgat gacgttgcta
    29161 tgttagtgga cggcgtaacc aaattaggga aaataaaata taaatcccac gaagagcagc
    29221 tagcagaaaa ccaccgaaag atgctgctag caatggctca agatttacga gttatcatgg
    29281 tcaaattagc tgatagacta cataacatgc gtacgttgaa gcacctgcga gaagataagc
    29341 aaagaaggat cgctcaggaa actttagaaa tctatgcgcc tcttgcacat cgtctaggga
    29401 tcagccggat caaatgggaa ttagaagata cagcacttcg ttatctaaat ccaaaacagt
    29461 attaccgtat cgtccacttg atgcagacga agagagaaga acgtgaaaaa tacgtaagtg
    29521 gtactgttga agatattcga atagcgacag aagagctggg gatttttgca gaaatctatg
    29581 gacggccaaa acacatttat tcaatctatc gtaaaatgaa agatcagaaa aagcagttca
    29641 acgaaattta tgacttgcta gctattcgag tgatcgtaga ttcaatcaag gattgttatg
    29701 ctgtattagg agcaatccac acaaaatgga aaccaatgcc cggcagattt aaggattata
    29761 ttgccatgcc aaaagctaat atgtaccaat ctttgcatac taccgtgatc ggtccggcag
    29821 gaaatccggt agaaattcaa atccgaacac aggaaatgca tgaaatcgct gaattcgggg
    29881 ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa agtagaacca gatggtatga
    29941 cgaaacaatt aagctggttc catgagatac tcgaacttca agacgaaagc tatgatgctt
    30001 ctgaatttat ggaaggcgta aaaggagata tctttagtga taaagtctac gtcttcacac
    30061 caaaaggaga cgttactgag ttaccaaaag gatccggacc attggacttt gcatacagta
    30121 tccatacaga tatcggtaac aaaaccactg gtgcaaaagt aaatggcaaa atggtgcagc
    30181 ttgattacaa attgaaaaac ggagatatca ttgagatcat gacttctcca aattcatttg
    30241 gcccaagtcg cgactggttg aaattagttg ctactagcaa agcaagaaat aagatcaaac
    30301 gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa aggccacgaa tccgtggtca
    30361 aatgtattac agatctagga tttacgccta aagatatttt gacgaagaac aaactgcaag
    30421 aagcactcga tcgttttaat tatcaaacag aagatgatct ctatgcagct gtagggtatg
    30481 gagaagttag ccccttgacg atggccaatc gtctgactga aaaagaacgt aaagaacaaa
    30541 aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa tcagccgaaa aaagaacctg
    30601 acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca aggggtagaa aacttactaa
    30661 ttcgtatcag tcgctgctgt aatccgattc ctggtgatga tatcgttggt tatatcacta
    30721 aaggcagagg gatatccatt catcgtcgag attgtccgaa tgttcagcct gacaaaccaa
    30781 atgtagcaga acgtttgatt gaagtcgaat gggaagatac atcgaataca cgaaaagagt
    30841 atgatgcaga tttggaaatt tacggctata atcgttcagg cttattgaat gatgtacttc
    30901 aaacagtcaa tgcgctaacg aaaaatctca acagcgttga agcacggacg aataaagata
    30961 aaatggcgac gatccatttg acggttggta tccagaattt atcccaccta aagagtatcg
    31021 tggataaaat caaagcagta cctgatgtct acagtgtacg ccggacgaat ggataggagg
    31081 acagatatga gagcagttgt tcaacgggta agtaaagctg ctgtgtcagt cgatcagcaa
    31141 gaaattggaa aaattggcta cggcctactt gttttattag gcattcatga aaccgatacg
    31201 caaaaagatg tggactatct ggtaaaaaaa attgcacaaa tgcgtatttt tgaagatgaa
    31261 caaggaaaaa tgaatattag tgtagaagat gtgggaggac aaattttaag tatctctcaa
    31321 ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa gctttgtgga agccgcacga
    31381 ccagaaacag ctattccttt atacgaatca ttcaatgaag gaatcagaag tcgcggcatc
    31441 acagtcgcta ccggacaatt cggagcagat atgtcggttt ctctcgtcaa tgatggacct
    31501 gtaacgatca ttattgattc taaaaacaaa taaagtaatc tggttttcac tagtaaaaac
    31561 tatgaaacac gtcgcttaag ttagactgat aaactctaac ttaagtggct tttttgtctg
    31621 caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta agcttaaatt atacaagtta
    31681 ttttttatag gaggttgctg aagatgaaag aagtaccagt agtagatatc aaaatcacag
    31741 atttaaaaaa attgtatcaa aaaggataca acatgttgga ggagttacgc catgaagcgg
    31801 acgctcccgt cgtcaaagca aagattttca ataaagaagc tatcacgatc tacggatcat
    31861 cagcagcaaa agtattttat gatccaagga atttcaaacg aaaaggtgct atgccaaaat
    31921 tagtattgaa gacacttttt ggtcaaggtg gagtacagac tttggatgga gctgctcatc
    31981 accatcggaa aaatattttt atggatctaa tgacaccgga aagaatggaa gattatcatc
    32041 gtatcttaga taagaatctg acacaagcac ttgaagcaca gcatggtcaa tttgaactat
    32101 ttgatttaag taagatggtt ttctttacat ctatttgcga gtgggcaggt atcaatttat
    32161 cagcgatttc taaagatgag gtcgaaaaat tagcagaata tcaaatctct atgatcagcg
    32221 gaacgtttac ttctccgatt gatcacataa aaggtgtcga gaatcgcaaa aaatcagaaa
    32281 aatgggcgca aggcttgatt gaagaagctc gacaaaatcc tgtggctgga aaagaaaatg
    32341 tggcattata tgcttttgcc aatgccacag atttagatgg tcagctttta cctctggaag
    32401 tggcagctgt tgaattattg aacatcatcc gtccaacggt tgctctaact gtgtgggcgg
    32461 cattgatggg acatgcactt ttcagtagac cagatttgta tcagcaatta aaaaatgact
    32521 tttcgacgtt acaagatccg tttattcaag aaatgagacg ctattatcct ttcttcccaa
    32581 tgctacctgc gatttcgctg aaagaagtag aagtagatgg ttatcgtata ccagaaggca
    32641 gttgggttat tttagattta tatggaacag accatgatga acgaacagtt gaagcgccag
    32701 attcctttat gatcaaacgg tatgtaggga aagcaaaaga tatttcctat aaagaagaat
    32761 atgagatgat tgcacaaggc gggggaaatt ttcgacaaat gcatcgctgt gcaggagaat
    32821 ggatcactct tcatagtcta cgtgtgtttt ccgatcagct agtaaataag tttgagttct
    32881 ctgtacctga acaagattgg acgattccat tcaatcagtt tccgacttat ccgaatagcc
    32941 gagcgctact ttacaagaat tagattagca taaacttatc gaaaaaaagg aagatcaaac
    33001 agtgctgatc ttcctttttt catattacta taaattgata aggtcaattg atcaaaatcc
    33061 acgaaatgct tcatcaatgg tttgataatc ttcattggat aaatgcaaat ctaaagcttg
    33121 gacattgtca gatacttgct ctggacgctt agctccaggt ataactacag acactcgtgg
    33181 attcttcatg taccaagcta aaacaagttg cgcaggagtg gcttggtatc ttttagcaat
    33241 ggggcgaagt acatcgacag cggttaaaat ttctctgaaa cgttctcctt ggaaatctgg
    33301 atttcttttt cgaggatctc cttcaccaaa ttgtttttcc tcaccaagtt catattttcc
    33361 tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa ctgattttgt ttttttcaag
    33421 ataagggaat aattcttttt cagcctgccg atggatcaaa ctgtatttat cttctactac
    33481 atcgacatat ccatctgcat tcgcttcttt caattgttct aacgtgaagt ttgacacacc
    33541 gactgctcgg atttttcctg cttcttttaa ttcgtgcaat gtagcaactg attcattttt
    33601 tggtgtgctt tcatccggaa agtggatata aaaaatgtcg atgtaatcag tttgcagacg
    33661 ttttagtgca tcttccaccg attgtttgag aaactcagga gaattatcaa atgttcgccc
    33721 tttatttggt acatgagcag cttttgtagc gatgacgaca cgtgagcgat catattcttt
    33781 ttccttcagt acctcgccaa tcagttcttc ggaacggccg tttccgtaag cataagcggt
    33841 atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact acttgttttc ctgtctcatc
    33901 ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt gctcctaatc caagctgttc
    33961 tgcgtagact tgtgaatgtc cgattcttat ttctgccata gctgattcct cctttttgtc
    34021 tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt tttgtgaggg gaaatagtca
    34081 gatatctctt gactttgaga ctggttttta gtaggttata agtaatatcg aatgtcaatg
    34141 aaagagcgag taagtttttg aaactttaca agagaggatc atcgaggctg aaaatgatct
    34201 aaagtttcat tagcctaaag acactctgga gatggacgag tgaaaagccg tcccgcgtac
    34261 gagcgttatt cgtaagagga aagagaaatc tttcaaaatt aggtggtacc gtgtatgaat
    34321 ttcattcacc cttgttcatg atgaacaagg gtgatttttt tatttacata gctaagaaag
    34381 ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa atgatatttt gccaggcgaa
    34441 tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat tattcagaga ttatcagtat
    34501 aatgaaatgc gtacaccgat ttttgaacac tatgaagtga tatcccgaag tgtaggggat
    34561 acaacggata tcgtttcaaa agagatgtat gatttttatg acaaagggga acgccatgtg
    34621 acgcttcgac cagaaggtac agcaccaatc gttcgttctt ttgttgagca taaattgttc
    34681 ggcccagagt atgcgaaacc gttcaaaact ttttatatgg gaccaatgtt tcgctacgaa
    34741 cgccctcaaa aaggacggtt acgtcaattc catcaaatcg gagtagaagc atttggatca
    34801 gaaaaccctg caactgatgt ggagagcatg gtgatggcac ttgatttctt caaacagttg
    34861 gggatcacgc aaatccggct agtcatcaat tcattaggtg ataaagaaac gcgtcaagcc
    34921 tatcgtcaag cattgatcga ctatctttta ccttttgaat cagagctgag tgaagactct
    34981 aaacgccgcc ttcatgaaaa tccattacgc gtattggaca gtaaagacaa acgagatcaa
    35041 aaatttgtgg cagaagctcc atctatctta gattatctaa gcgagcctgc tcaaaaacat
    35101 tttgataccg ttgtttccat gctggatgca ttggctgttc cttatgaaat cgacagtaat
    35161 atggttcgcg gactagatta ttacacacat acgatttttg aaatcatgag tgacgcacca
    35221 aaaatggggg cacaagcaac gatttgcgca ggcggacgtt atgacaatct agtggaagaa
    35281 ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg gtatcgagcg attactcttg
    35341 actatggagg cagaggaagt agttatccct gcatttaatg agttggatgc ttacgtggtc
    35401 gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg tccaagcgat tcgaaacttt
    35461 ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa aagcgcaatt taagacagca
    35521 gataaagcga atgccaaatt agtattggtg atcggtgaag atgagcttgc tagtcaaacg
    35581 attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt ttccattaga agagatatat
    35641 gaacattttg atgaagtcta tgatgaaatg actttattcg agtaggagga aaaaaataaa
    35701 tggcacaaag aacgatctat tgcggattag tttccgaaca acaattagaa caaacagtta
    35761 cattaaaagg atgggtacaa aaaagacgag accttggggg agtaatcttt atcgacctac
    35821 gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga aatcaacaaa gaagcatggg
    35881 aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt gactggggaa gttagaagac
    35941 gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga attcgaagtg attgcaagtg
    36001 aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca aattgaagat gatcaagcaa
    36061 tcagtgacga aatacgtttg aaatatcgtt atttggatct gcgtcgtcca aaaatgacta
    36121 aaaacatcaa attaagaaat gcgacaacaa aagcgattcg tcattattta gatgataatg
    36181 actttctcga tatcgaaaca ccttacctag ggaaatctac accagaaggc gcaagagact
    36241 acctagttcc ttcacgtgtc catgctggac atttctatgc gttgccgcaa tctcctcaat
    36301 tgtttaaaca attgctgatg aatgctggat tcgaccgtta ttatcaaatc gttcgttgtt
    36361 tccgcgatga agatttacgt ggagaccgtc agcctgaatt tacgcaagta gatattgaaa
    36421 caacgttctt aacagcagaa gaaatccaaa cttacacaga gggattgatt gcgaaggtaa
    36481 tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc tcgtatgacc tatgatgaag
    36541 caatggctcg ctacggcagc gacaaaccgg atacacgttt tgatatggaa ttgatcgatc
    36601 taagcgatac agtcaaagaa gtagaattca aagtcttcca aatggctctt gaaaacggcg
    36661 gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg ctactcacga aaagacatgg
    36721 atcagttagg tcaatatgta ggacaattcg gagctaaggg gcttgcatgg ctgaaagtag
    36781 aagaagacgg attgaaaggt ccaattgcta aattcatggg agaagcaaca gaagcaatca
    36841 ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt tggcgcagat aaaagtgaaa
    36901 tcgtcgctgc tgcattaggt gctatccgga cacgtttagg aaaagaatta ggactaattg
    36961 atgaatcgaa attcaatttc ttatgggtaa ctgattggcc acaatttgaa ttttcagaag
    37021 aagaaggtcg atatgtctct gctcaccatc cattcacgat gccaaaagaa gaagatatcc
    37081 cgttattggc tgaagaccct gcaaaagtct atgcagaagc ttatgatatc gtcttgaacg
    37141 gttatgaatt aggcggaggt tctatccgta ttcatactcg tgagcttcaa gaaaaagtac
    37201 tagaaactct aggctttaca aaagaacaaa tggaagaaca atttggtttc ttgttaacag
    37261 ctttagatta cggattccct ccacatggcg gtattgcatt aggattggac cgttttgcaa
    37321 tgttattagc cggagaagat aatattcgtg aagtcattgc ctttcctaaa aacggaaaag
    37381 cagcagatgt gatgagtgat gcaccaagta tggtttcgcc tttacaattg ttcgaattga
    37441 atattgatgt aacgaatata gaagaatagc cgataaaaag gtaaaaagga tttgtcgaat
    37501 acgcttcttt tgacaacctt gatttaattg aaaaacactt tataatgaag ccataacata
    37561 taaagcgggg cttttccatg aaaaaaacat tcgaaaattg ggcttatcat gattacacga
    37621 ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc agtcgcattg aatttctttt
    37681 atcagccagg acatatttat tcaagtggta ttactggtct agctcagatt ttgacgactt
    37741 tgtcaaaatc actgatagga ttcgaagtac cggtatcaac aactttgtat ttactgaata
    37801 tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa gtttacaatt ttcactttta
    37861 tcacagtcac tttgacctcc ctttgtatcc atattttacc ggaaacagtc ctatctaccg
    37921 atccaatcat ctgtgcgttg tttggggggg ctgtgatggg actaggtatt gggctagcgt
    37981 tgagaaacgg cctatcatcg ggcggtctag atatcgtgag tatcacgatt cgtaaaaaaa
    38041 caggaaagtc gattggttct atttcgatct acttcaatgc attgatcgtt tttgttgccg
    38101 gaattctatt tggctggcaa tatatgtttt acagtacgtt gtctattttc gtcagtggaa
    38161 aagtaactga tgtcgtttat actaaacaaa agaagatgca ggtaatgatc gtaacgaaac
    38221 atccagaaaa agtagtaaat gaaatccaaa actgtatgcg tagagggatc acgatcatca
    38281 atgaagcaga aggtgcttat aagcatgata agcagacagt attgatgacg atcgttacac
    38341 gatacgaact gcctctactt agagaagcaa tgaaagcttc tgatccacaa gcttttgtaa
    38401 gtattgcaga aaacgtccag atacttggtc gtttctatga ggatggcatt tagatcgagt
    38461 ttgacaaaaa ttcatgaaat actgctgtag acagacgttc gtttgtctgc agtttttttc
    38521 taccatagta gaatcagcaa agaaaaactg cttttttatt tgaaattttc ttaaagttga
    38581 aaaaaagcat gtttattttt ttaaatttat gggatgatag aaaaaaatag tagagaaagg
    38641 acacgattct acttgctatt ttcacttaat acccgtatat tacgaatgaa aaaagtttat
    38701 gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa aaaacagccg ctacatcact
    38761 gggtttgatg ggctccgttc attagctgtg gtgggtgtta tcttctatca ccttctgcca
    38821 actagtatga aaggcggcta tttgggcgtt ccgatttttt tcgtcgtatc tggttatttg
    38881 atcacggatc tgctgcggca ggaatgggaa caaaatggaa aaatcaatat ttggcaattt
    38941 tatgtcagaa gaatgaagag actctatccg gcacttgttt ttatgcttgt gacagcttcg
    39001 gcttatatca ctttgtttca gcgagggctg ttaaacaatc ttcgaggagt tgtggtcagc
    39061 agcttactgt atgtcaacaa ctggtggcaa atcaataacg gtttatctta tttcgatcga
    39121 tttgctaatg agtcaccgtt tacgcatatc tggtctttag cagtagaagg tcaaaactat
    39181 ttggtttggc cgatcttgtt tgtattgttg atggtatttg ttcgtaaaag aaaatggatc
    39241 ttttatactg tgttaggtac atccttcctc tccgccatct tgatgatgat cttgtataca
    39301 ccaggaggcg atccaacccg tgtttattac ggtaccgaca ctcgtctgtt ttctatatgg
    39361 ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt taaagaaaaa catcccgaaa
    39421 caagcgaaaa atattctgaa tatcgctgga ggaatctcgc ttttggcact gattctttgc
    39481 ttcttctttt tagatgatca ttacaatttc atctattacg gaggaatgct cctagtgagt
    39541 ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg gagcaagttt gaatcgatgg
    39601 ctgacaaatc cagtatttac ttggattggc aaacgaagct atggcattta tctgtatcag
    39661 tttccagtta tgatttttta tgaagcaaag gtgactgata ttgccgatca tgttttgttg
    39721 catactttag tggaaatcac attgattcta atcatcagtg aactttctta tcgatatgtg
    39781 gagcgtccgc tagcacgttt tgattatggt cgtacattcc aagtgatgaa aggatggttc
    39841 agcaaaccga tcatcagtaa gagcaaacca tgggttgttc caggcacatt acttgtagca
    39901 attgcactcg ttggtttcgt tacggcaccg aaaaacgctg taacagccga tcaaaaacaa
    39961 ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag aaaccagaaa caattcagaa
    40021 aacaccacta gttcggttga ccaagcgatc cttgataagt acgagttgtc caaggcacaa
    40081 gggaataagg cacaaaaatt agaactaacg gcatttggtg attcagttat gttggatgct
    40141 gcaacggatc tacaagaact ttatccaaaa gtagtggtag atggagatgt cggacgacaa
    40201 ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac aagatttgtt gaaagacact
    40261 gttctgattg gactaggaac gaatggctca ttctcggaag ctcagtttga tagtgtgatg
    40321 gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc gagtaccgac gaagcgctgg
    40381 caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa aatacgacaa tatgacgctg
    40441 attgattggt acagctacag taatgaccat agtgactggt tttatgatga tcaagtccat
    40501 ccaaatcctg aagggatgac acattacatt cacttagtca gcgaagcctt gctaggagga
    40561 agttcaagta cgaacagcag tgagacaaac gtgacagaat gatagctaca aaaaacttca
    40621 ggcaaaaaca tttgtttttg cctgaagttt ttttatattt accgtgtttt taacattcat
    40681 atagattcag gaagcaaaac ggttgagtgt gtctgtaaat aacgttcttt ttgttttcgg
    40741 gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc ttcttgaaga aaatacttct
    40801 gcatggatca tcttaacagg tcttcttttt tgaagacgag tatatttagc accagtacca
    40861 ttgttatgtt cctctaatcg tctagaaaga tcggttgtat atccaccata aaatgtctga
    40921 tctttacaga ataatacgta aaaataatgt tcatttgcca tagagcatct cacgaatctc
    40981 tgcagtgtat tctccatcca tattgtaagt gatcaatggt ggagcgactt tgaatccgtc
    41041 taatttgcct tctttgattc cttcaactaa caaaatattt gcctcttttc caggttttgg
    41101 gtaaacaaat tggatccttt taggtgcaat tcgatagtct tccatgacct gaatgatttc
    41161 taagaaccga tcaggacgat ggaccatagt aaagcgtcca tttgttttta gtagcttact
    41221 tgaaatatcg atcacttctt ctaacgtcgt atgaatctca tgacgggcga ttgccaggtg
    41281 tttattaggg ttcgttttat ttgttggcag ccctttgaaa taaggtggat tacagacgac
    41341 taagtcacaa gaattatgtc gaacgacaga taagctgtct ttcagatcga tggtgtggac
    41401 agtcatttgt tcatttaaat ggttaagcgc gatactacgt cttgccatgt ctgctagacg
    41461 aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt ttacttaaaa aaagtccaac
    41521 tgcgccattt cctgcacaaa ggtcaacaat cttccctttt ttaggtacac gggaaaagtg
    41581 agcaagcagc acagcatcta aagaaaaaga aaacactttg gaactttgga taatcttgat
    41641 atcttctgcg tataattggt cgattcgttc gtcttcgtga agcatggatt ccctccaaaa
    41701 tgaaaaaaat agtcgtctgt attatactat ttttattaaa aagaaccaag gtggcttgtc
    41761 aaacctctat tttttatgca tactatgacc ataagaaggg aaaggaagag actatgtttt
    41821 atcgatttat gcgcggggta gttcgagtac tattagcctt agttaatgga aatgcccgct
    41881 atgagaataa agaagtttta ccgcaagatg agaattacat actagttgct ccccatcgta
    41941 cttggtggga cccattatat ctggcggtag ctgcagcacc caaggaattc agctttatgg
    42001 caaaagaaga actgttcaaa aatccagttc tgcgatttat attaactcga tccaatgctt
    42061 ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa aacacctgta aagattttga
    42121 aatcgacaaa tttgagtttg atcatgtttc ccagtgggac aagacatgct acagaactta
    42181 aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa aatcgtgcca gctgtatatc
    42241 aaggtccgtt gacacttggg gatctgttca agcgtcagag agtgacagtg cgtttcggcg
    42301 aaccaatcga cttatcagat atcaagaaaa cggataaaga aggtatggcg gagatcgaac
    42361 gacgaacaca agcagctttt gacaaattgg acaaagaagt gaaccctgat ttcaaatatg
    42421 aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg gtcttttgaa tctactgtcc
    42481 tgttcagttc agactttttc aatgaaaacg agggagagac gtcaagtctg ccctcttttt
    42541 gcgttccaat atgtaaaata gaagacaggt gtcatgtaat ggatcaaagt gttataataa
    42601 ttagaaggac attttttgag gtgattgaat gcgtttttta catacagccg attggcatat
    42661 cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag cgtcatgtac tatcttctat
    42721 actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg attgccggag acttatatga
    42781 taggagtgtc ccagctgttg atgccgtaga attatacaat gaattgatgg tcgattggaa
    42841 tttaaaggaa aagatcccga tttttgctat atcaggaaat cacgatagca gtacgagact
    42901 ttcagcgggt acgccatggt tcagttattc gaactatttt ttgcgaacac agctagcaga
    42961 agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc tttcttcctt actttgaacc
    43021 aattgcagcg agattatatt ttgaagatga caatatccga acgatcaagc aagcggtagc
    43081 caaggtgata gataaaatgc aggagctatt tgattcagaa aaaaaacaag tattgattag
    43141 ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa acgaaaatcg aagtaggcgg
    43201 gttggattcg atccctggtg aactacttac accgtttgat tatgtagcac taggacattt
    43261 gcataatcaa gctgctttga gacaggataa tgctcgctat agcggttccc cattgaaatt
    43321 ctctttatct gagatcaacc aaaaaaaagg cgtatggatc gttgacctga caacaggcct
    43381 ggagttgaat tttagggaga tcgaacccct gcatgatatt gaagaaataa cagcgagttt
    43441 caaagaattg ctggatcctg ccttttatca gtccgtcaat cgggagaatt acatctatat
    43501 ctatctcact gatagaacga tcatcccgaa tatgatgaac cagcttcggc aaatatatcc
    43561 tcgtattttg gggattgaac gggcaaacgg tcgagcagaa caaacaaagc gcaaacgaaa
    43621 agtactagaa atgaaagatc ctcaaaaatt agcagaagca ttttttagtg aaatgacgga
    43681 agagcagcta actgcaaacc aagaaaaatg gctcggagaa acgttgcaag aaatcatgga
    43741 aatggaatga tcaagaatga aaccgaaaaa attacaactt aaaaattttg gtccttttat
    43801 caatgagacc gtagattttt cacgtttgac agaagcaccg ctttttttga tcagcgggaa
    43861 gacaggagct ggcaaaacga cgatttttga tgggatcacc ttcgcacttt ttggtgaaac
    43921 ttccggaaga cttcgctctg gaaaagagat gcgttctttg tttgctacac cagacgaaga
    43981 aacaagcgtg actttttctt ttgaacatca gcagatgagc tatgaaatcg aacgaaaacc
    44041 agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa aaacaggcag ccaaagtaac
    44101 gttgaccatt tttgatggga aaggaaaaga aataaaacaa atcacaaaac gtacagaagc
    44161 agatcagttg atcagagaac tgatgaatct cgatgcgaaa cagttttctc aaatcgtttt
    44221 actaccccaa ggagaattcc gtaatttttt ggtttcatca agcagtgata aagagactgt
    44281 tttacgtcat ttattcggta ctcaattttt ccaacagttc aatgagcgat taaaagaaaa
    44341 agcaaaacaa cagcaacaaa aattggatca tttagagcaa gagctgcatc ttctgcaaaa
    44401 aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg tttgaagccg ttttagccca
    44461 atggacaaac catcaggcaa tactcgaaaa acaaatcacg gaagaaaaag aagctctaac
    44521 ggaacttcag gaaaaacaaa agcaactaga aaattcctac tatcgttttg aaagcttgaa
    44581 aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa aaggaattag ctgctcaaaa
    44641 agacgaaata gaggaaaaga aacgatggat tgggtattat gaatttacgc aacgattagt
    44701 cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa atagaactgt cacaaaaaag
    44761 tagtgagcaa acaaagaaac tagcgatgac tacgcagaat tatgaagagt ggcaaaaaaa
    44821 tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa gctgctcaaa aactgcaaaa
    44881 caaacagatg atggtgccaa ttgtcgaatc cttacgtagt aaaaaacaag acgcagaaca
    44941 attaacaatt tcattggata aagaagaatt gaatgccgag aagctgtatc aaaatctcgc
    45001 tatctatcag gaaagaactc gaattcttca agaaaattta ctggatcagg aaaaactgca
    45061 agaagatcgt cttgcttttg gacagttaaa atatctagat gaaaagcagc aagaaataga
    45121 aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata agagaagaac tcaaaaaagc
    45181 aactgaagaa ataacaaaaa atagtcagct attgaaagaa cagacagaac aagcagaaca
    45241 gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt cagctttttt tgcgtccagg
    45301 ggagccatgt cttgtttgtg gatcaacgga acaccccata caacaattaa aacacgaaca
    45361 gccaaataag gaagatatct taaaagtaga acaacaactg gcagaagctg agtctgctgt
    45421 agaaagaact cagcaaatca ttgccaaaag tgaagcacat gaaaataatc ttcaacaaca
    45481 attatcagat ttagaacaaa aaatcatggc aacgaatata caattggctg aacaagaaga
    45541 acacttgcaa caggctttga aaaaggcatt tcctgagata acagaacaaa aaacaaaaac
    45601 aactcttgta gtaatcgaac aatctttaga tagacgaaaa agcaagatgg ccaatgaaag
    45661 aatagagctg gaagaaataa gacaacaagc agaaaagctc gaacaacaat tagctgtcta
    45721 caaacagcag cagacagaaa aaaataatca gctccagcaa ctgcaaggag aaatcaaaag
    45781 tttagaacaa caattgcaag atacggatag taactgttta gaagaggaga tacgacgact
    45841 tgaaaaacag ttagaagaag actcgaatca actagctgtt gagcagaaag caggagtgca
    45901 attgttgcaa gatcttcata cgcttcggac acagcttgat cttcaacatg aacaaataga
    45961 aaaaatagat gaaaaaatag aaaaggaaca agaaagaata gctaaaaagt tagaaagcca
    46021 gtcgtatttt tcaacaattg aagaaatctg tgcatttgca caacagcaag cacaatataa
    46081 agaaaaccaa cgtacagtta cttcttatca tgaagagcaa ttagtgacag ctgaccggct
    46141 gcgtcaatta gaaaatatcc agctaactga gacattccca gatacagaag agatcagcca
    46201 acagttagaa gaaataagac gtatgatcga aataaagcaa gaaaagatat acggtttaca
    46261 agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt ctttcgattt atcacacaag
    46321 ccagacgaaa ttagatgagc ttacgcaatt acagcagctt tcgcaaacat tcaacggaga
    46381 aaatcctaag aagactagtt tggaacggta tgtgcttcag gtttatcttc aagaagtgtt
    46441 acaagtagca aatgatcatc tccaacgttt aacgaaaaat cgttatcaat ttgagctagc
    46501 ggataccatt ggcagttatc gagggaaaac cggattagaa atcaatatct atgatgatca
    46561 ggcaggtatg tctcgaagtg cgcataccct gtctggcggt gagagtttta ttgcagcact
    46621 ttctttagca ttagctcttg ccgatgtgat ccagacacaa gctggtggtg tagcaatcga
    46681 tgcattgttt attgatgaag gatttgggtc attagatgaa gaagctttgg aaatggcaat
    46741 ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc ggcatcatta gtcatgtaag
    46801 agaattgaaa gaacgagtat tacaacaaat aagaattgat acagaaggta gcggacaaag
    46861 caaaatacgc tatcaacttg gataaaaagg gagattggta actatgaaat ggagtattcc
    46921 agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa ggccgagtgt tatcggttgt
    46981 ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg ggcagtgaat tgtatatggt
    47041 tgatttggat ggtacagcaa aagagataga ttactgccaa tgtccctatt gggaggaaca
    47101 taaatattgt aagcatacag ttgctgtgga actttattta cggtcgaaaa atctatctcg
    47161 tatcatgaaa aaagaccagc caatgctaga accggtaaaa gcaacaagtg agggagaaat
    47221 cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat cctcaagcgg tgcaaccttt
    47281 gattattgaa taccaagtag aaacgattga gactaatcag tatcacccag agctttctat
    47341 tttggcactt tacttgcgta tcggttcatt ggcatcaccg aaaaaaacat atatcgtaaa
    47401 aaacatctat gattttttac aagcttacac agaaaaagaa acttacactg ttaataaaca
    47461 gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa gatcaaaaaa tactcacgca
    47521 tcttgcagga agtgctcaga cgcatcaatt attaggtacg aacggcttac aagtcaaagg
    47581 aaaactagat aaaagatatc tgcttctccc agtagaacaa gcccgcttcc tgttagagca
    47641 gatgaatcag actacacgtt tgcatctgca gataaatgaa caaaacgatc aaggaataca
    47701 attttctgat caaaacaaac ctttatcatt caaagtggaa aaatttggag aagattattt
    47761 gctgcaagca ttgaatgatt ttgatttttt ctttatgcat tatcagtggg gagttatcca
    47821 agggacattt tattctctga cgaaatatca acaaacggtt tatcaaactt ggaaacaatt
    47881 gattcgccga ttggagaaac cagaagtagt gttcaagaaa aaagaattac cgtctttgtt
    47941 taaagagatt atccctctgc tgtcagagat cggcgacgta gctattgccc ctgcagtaga
    48001 agaggaagta gcagatatcc ccgtcgaatt tattttcttt ttccgaaaag caaaaggaaa
    48061 aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc tattcgactg acccgaagca
    48121 tgaggtctcg acagaacagg cttttcaggt gttacgtgac acagtagaag agaaacgagt
    48181 acttgatcta ttcagaatgt atcgctacca gaaaaatgaa actggttatg aacgtccatt
    48241 gccaagcggg gaagaactat atgccttttt ccgcacagaa ctatctgtct tccgtcagtt
    48301 tggtgaagtc agacttggaa gaaaattgcg agagttgtat ttagatgcgc ataaacatca
    48361 accgaaaatc gaagtaaccg agaccggttc atggctcgat attcgattcg atgtgacagg
    48421 gatagaggag caagaaatcg atcatgtcct gcaaagcttg ctgagaaatg atgcttttta
    48481 tacattagaa aatggtcagg ttctttcttt tgattcagaa gaatttcaac aaacaagcca
    48541 agtgttgcaa caattacggg aatcgatacg tacagaagaa ggaacgatcc atgtacctaa
    48601 aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc aatgctactt ttagtgaatc
    48661 gttccaaacg atggtacaag atctcattca tccagaaaga taccaggcac agcttcccaa
    48721 aggattgaat gcaacgatga gagattatca aaagcaaggt tttcgatggt tgaagatgtt
    48781 aggtcattat cagtttggcg gtattttagc cgatgaaatg ggacttggga aaacactaca
    48841 gacaattgcc tttttacttt cggaaaaaga agaacggaaa agcttctctg ctttgatcgt
    48901 agcgcctgcg agcttaattt acaactggca ggcagaggtg agaaaattcg ccccttcttt
    48961 aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa gaattactgg ctaaagacac
    49021 agatatccga gtgacttctt atgccagctt aagacaggat ctagctaatt atcagtcgca
    49081 aaaaattgat tatttgattc ttgatgaggc acaaatggtc aaaaatagca gtacgaaaac
    49141 tgcacaagca ttgagagaat tagctgtacc tcagcggttt gcactgagtg ggacaccaat
    49201 cgagaataat ttagaagaat tgtggtcatt gtttgcaacg attatgccag gatttttccc
    49261 gactaaaaca aaattcaggg aacttgccgc agaagaaatt gcgcaaatga ttcgaccgtt
    49321 tattttacgg cgagataaac aaactgtgtt gaaagacttg ccggaaaaaa cagagatgaa
    49381 tctatattct gcacttacag aagaacaaaa aactgtttat ttagcttact tgcgtcaaat
    49441 gcgtgaagaa atcacatcaa tggattctga agcattcaag aaaaaccgga tcgggatact
    49501 tgctggtctg acaagactgc gacaaatttg ctgcgatcct cgtctgttta ttgaagatta
    49561 ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta ctggtagctg ccaaagagaa
    49621 caaacgaaga gttttgctgt tttctcaatt tacagggatg ctgactatct tgcaagaaga
    49681 gttagccgag ctagggatct cgacatttta tttaagaggc agtacgaaac cacaagatcg
    49741 gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat gtttttctga tttccttaaa
    49801 ggctggggga actggattga atctcacggg agcagatacg gtcatcttgt atgacctttg
    49861 gtggaatcct gccattgaag aacaagctgc tggacgtgca catcggatcg gacaaaaaaa
    49921 tgtggtagaa gtgtggcgta tgatctctga aggaacgatt gaggaacgca tggattcact
    49981 ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa ggtaatgaag aacagttgac
    50041 gaaactgact gaagaagaca tccgcatgat tttaagtgta ggagaaatcg aggagtaaga
    50101 gactcgaaaa agcgttcagt aatgggtaag aaagcctttc taaagaagcg attgtttatt
    50161 tgatttaaaa aatagcaagg aggctgggat tccattttat cccagcttcc ttgctatcat
    50221 ttttttattt ctatttttaa aggttataca aagattgtct tcattgtctc taacagctga
    50281 tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt caattttgcg ttctcgatgg
    50341 ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta gaacatcatt gtcgtaatta
    50401 tcgccaacgt ataaggtctc ttctggaagc atatgaaatt ctttctcagc cagctgaaaa
    50461 atctcttttt ctggtttttg gaaacctgtt gcttgagaaa tgagcatatt gcgggaagga
    50521 atccaattgt tcaattgaag ttgcttcagt ttttttgtct gatggtcagt cggcccattt
    50581 gtgataattc ctaatgggac attcttttcc ttcaagaaat cgagggtttt tttgacctcc
    50641 tcatgcaagc agatattatc aagttcttcc tcgtaaattt tttgaaataa gaggccatct
    50701 tcttccgtaa tatgagggta gtctaaatct tttagtgatt ggctgatccg atgtgctcgc
    50761 atatattcta gtgtccaatc tcctgccatt acttttggga agttttcatc actatgatgg
    50821 cggaaccgga tatatagtgg atgcatatct gcatctgaaa caagcggaac gactcttttg
    50881 accgcgtttc gaaatggctg ctgctgatca tacatcgtat catcaacatc aaacacaact
    50941 gatttaatca aaattttaca cgcctttcgg ttttcattga ttttttcaca aatccttgac
    51001 tattgtaaca gaaaaaattg tctaaaaaag ctgataaata aaggtttttc ttactatatt
    51061 tctatttcct tgacagaata aggtttttat atttcagttt ttttcactaa aaatcgtgaa
    51121 acacgtcaat aagtttgatg aacaaattaa tcattatggt agaagtcgat tgatttattt
    51181 taatgcaatc tctgtggaat tttcgaaaga tttatttttt taatacagtc tcaatataac
    51241 tattcaaaca taaaataacg ttatttgatt tatttgttta tagtaaattt tatttagtaa
    51301 tc
//
LOCUS       DACGDM010000013        50702 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.013, whole genome shotgun sequence.
ACCESSION   DACGDM010000013 DACGDM010000000
VERSION     DACGDM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.013"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            162..392
                     /locus_tag="IXR05_000813"
     CDS             162..392
                     /locus_tag="IXR05_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAQ4259353.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            489..1790
                     /gene="murA"
                     /locus_tag="IXR05_000814"
     CDS             489..1790
                     /gene="murA"
                     /locus_tag="IXR05_000814"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4259354.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1803..1979
                     /locus_tag="IXR05_000815"
     CDS             1803..1979
                     /locus_tag="IXR05_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4259355.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2114..2410
                     /gene="yidD"
                     /locus_tag="IXR05_000816"
     CDS             2114..2410
                     /gene="yidD"
                     /locus_tag="IXR05_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAQ4259356.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2474..2941
                     /locus_tag="IXR05_000817"
     CDS             2474..2941
                     /locus_tag="IXR05_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4259357.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3026..3910
                     /locus_tag="IXR05_000818"
     CDS             3026..3910
                     /locus_tag="IXR05_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4259358.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4027..4260
                     /locus_tag="IXR05_000819"
     CDS             4027..4260
                     /locus_tag="IXR05_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAQ4259359.1"
                     /translation="MSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4348..4428
                     /locus_tag="IXR05_000820"
     tRNA            4348..4428
                     /locus_tag="IXR05_000820"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4382..4384,aa:Tyr,seq:gta)
     gene            4435..4506
                     /locus_tag="IXR05_000821"
     tRNA            4435..4506
                     /locus_tag="IXR05_000821"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4467..4469,aa:Gln,seq:ttg)
     gene            5021..5728
                     /locus_tag="IXR05_000822"
     CDS             5021..5728
                     /locus_tag="IXR05_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4259360.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5788..6432)
                     /locus_tag="IXR05_000823"
     CDS             complement(5788..6432)
                     /locus_tag="IXR05_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAQ4259361.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6559..6846
                     /locus_tag="IXR05_000824"
     CDS             6559..6846
                     /locus_tag="IXR05_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259362.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6954..7274
                     /locus_tag="IXR05_000825"
     CDS             6954..7274
                     /locus_tag="IXR05_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4259363.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7355..8668
                     /locus_tag="IXR05_000826"
     CDS             7355..8668
                     /locus_tag="IXR05_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4259364.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8665..9384
                     /locus_tag="IXR05_000827"
     CDS             8665..9384
                     /locus_tag="IXR05_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAQ4259365.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9512..10063
                     /gene="raiA"
                     /locus_tag="IXR05_000828"
     CDS             9512..10063
                     /gene="raiA"
                     /locus_tag="IXR05_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAQ4259366.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10285..12819
                     /gene="secA"
                     /locus_tag="IXR05_000829"
     CDS             10285..12819
                     /gene="secA"
                     /locus_tag="IXR05_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAQ4259367.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            12945..14046
                     /gene="prfB"
                     /locus_tag="IXR05_000830"
     CDS             join(12945..13007,13009..14046)
                     /gene="prfB"
                     /locus_tag="IXR05_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAQ4259368.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14151..14837
                     /gene="ftsE"
                     /locus_tag="IXR05_000831"
     CDS             14151..14837
                     /gene="ftsE"
                     /locus_tag="IXR05_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAQ4259369.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14821..15714
                     /locus_tag="IXR05_000832"
     CDS             14821..15714
                     /locus_tag="IXR05_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259370.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15866..17314
                     /gene="cls"
                     /locus_tag="IXR05_000833"
     CDS             15866..17314
                     /gene="cls"
                     /locus_tag="IXR05_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4259371.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17651..18508
                     /locus_tag="IXR05_000834"
     CDS             17651..18508
                     /locus_tag="IXR05_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAQ4259372.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18623..19543
                     /gene="pstC"
                     /locus_tag="IXR05_000835"
     CDS             18623..19543
                     /gene="pstC"
                     /locus_tag="IXR05_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAQ4259373.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19543..20427
                     /gene="pstA"
                     /locus_tag="IXR05_000836"
     CDS             19543..20427
                     /gene="pstA"
                     /locus_tag="IXR05_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAQ4259374.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20442..21248
                     /gene="pstB"
                     /locus_tag="IXR05_000837"
     CDS             20442..21248
                     /gene="pstB"
                     /locus_tag="IXR05_000837"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259375.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21264..22022
                     /locus_tag="IXR05_000838"
     CDS             21264..22022
                     /locus_tag="IXR05_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259376.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22035..22712
                     /gene="phoU"
                     /locus_tag="IXR05_000839"
     CDS             22035..22712
                     /gene="phoU"
                     /locus_tag="IXR05_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAQ4259377.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            22950..23981
                     /locus_tag="IXR05_000840"
     CDS             22950..23981
                     /locus_tag="IXR05_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4259378.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            23978..24745
                     /locus_tag="IXR05_000841"
     CDS             23978..24745
                     /locus_tag="IXR05_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4259379.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24845..26413
                     /gene="liaX"
                     /locus_tag="IXR05_000842"
     CDS             24845..26413
                     /gene="liaX"
                     /locus_tag="IXR05_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAQ4259380.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26713..27030
                     /locus_tag="IXR05_000843"
     CDS             26713..27030
                     /locus_tag="IXR05_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAQ4259381.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            27030..27380
                     /locus_tag="IXR05_000844"
     CDS             27030..27380
                     /locus_tag="IXR05_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAQ4259382.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27547..28485
                     /locus_tag="IXR05_000845"
     CDS             27547..28485
                     /locus_tag="IXR05_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAQ4259383.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28500..29330
                     /locus_tag="IXR05_000846"
     CDS             28500..29330
                     /locus_tag="IXR05_000846"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAQ4259384.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29374..30399
                     /locus_tag="IXR05_000847"
     CDS             29374..30399
                     /locus_tag="IXR05_000847"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4259385.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30414..31352
                     /gene="galU"
                     /locus_tag="IXR05_000848"
     CDS             30414..31352
                     /gene="galU"
                     /locus_tag="IXR05_000848"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4259386.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31477..31917
                     /locus_tag="IXR05_000849"
     CDS             31477..31917
                     /locus_tag="IXR05_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAQ4259387.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            31920..32522
                     /locus_tag="IXR05_000850"
     CDS             31920..32522
                     /locus_tag="IXR05_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4259388.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32581..33687)
                     /locus_tag="IXR05_000851"
     CDS             complement(32581..33687)
                     /locus_tag="IXR05_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4259389.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            33897..34898
                     /gene="ccpA"
                     /locus_tag="IXR05_000852"
     CDS             33897..34898
                     /gene="ccpA"
                     /locus_tag="IXR05_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAQ4259390.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35235..37580)
                     /locus_tag="IXR05_000853"
     CDS             complement(35235..37580)
                     /locus_tag="IXR05_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4259391.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            37859..38761
                     /locus_tag="IXR05_000854"
     CDS             37859..38761
                     /locus_tag="IXR05_000854"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAQ4259392.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            38974..40749
                     /locus_tag="IXR05_000855"
     CDS             38974..40749
                     /locus_tag="IXR05_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAQ4259393.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40815..42401)
                     /locus_tag="IXR05_000856"
     CDS             complement(40815..42401)
                     /locus_tag="IXR05_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAQ4259394.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            42652..42876
                     /locus_tag="IXR05_000857"
     CDS             42652..42876
                     /locus_tag="IXR05_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAQ4259395.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            43018..44769
                     /locus_tag="IXR05_000858"
     CDS             43018..44769
                     /locus_tag="IXR05_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4259396.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44769..46553
                     /locus_tag="IXR05_000859"
     CDS             44769..46553
                     /locus_tag="IXR05_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259397.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            46879..47730
                     /locus_tag="IXR05_000860"
     CDS             46879..47730
                     /locus_tag="IXR05_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4259398.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47784..49535
                     /locus_tag="IXR05_000861"
     CDS             47784..49535
                     /locus_tag="IXR05_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4259399.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            49539..49709
                     /locus_tag="IXR05_000862"
     CDS             49539..49709
                     /locus_tag="IXR05_000862"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259400.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(49749..50651)
                     /locus_tag="IXR05_000863"
     CDS             complement(49749..50651)
                     /locus_tag="IXR05_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4259401.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
BASE COUNT        16422 a         8845 c        10789 g        14646 t
ORIGIN      
        1 ttttgtctca gtcccttttt ttgcatattt ttagcattta tttcctaaaa aatgtaaggg
       61 gattcctata tttttaagta tacttgtttt tccttttata cattttatgg tattatcatt
      121 ttattagtta ttataaaaca atcgttagaa aggacgtcat tatgcaagta tacggaattg
      181 atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta cttagccttc tggtctttac
      241 gttcgttacg cattgaaact tttttcagac caatgcataa tacgcaaatt agaatggcaa
      301 tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa ttttttctta gaagttatcg
      361 ctttatgccg aaatcttttc gttagcctgt aaattttaaa aaaaggtact attttaaaag
      421 caaggatgtt ataatagaaa agattttgag taagtgtatg ctcattggaa ttttttggag
      481 ggaacaacat ggaagagatc atcgtaagag gtggcaatca attaaatgga acagtaagaa
      541 ttgaaggagc taaaaatgct gttttgccta ttttagctgc tagtttgtta gcagaagaag
      601 gtattacgac attagacaac gttccgattc tttctgatgt cttcactatg aatcaagtga
      661 ttcgtcactt aaacgtagat gtagattttg atgaacaaaa gaatcaagta acaatcgatg
      721 cttcaagaca attagaaatc gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa
      781 tcgttgtgat gggtccgcta cttgccagaa atggacatgc aaaagtagct atgcctggtg
      841 gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa aggatttcaa gctttaggag
      901 caaaaattat tcaaaaaaac ggctatatcg aagcaattgc ggatgaattg atcggtaaca
      961 cgatttattt agatttccct agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa
     1021 aagcaaaagg aacaaccatc attgaaaacg tagctcgcga accagaaatc gttgatttag
     1081 caaacatttt gaataaaatg ggcgctcaag tctatggagc tggtactgaa acaatgcgta
     1141 ttgaaggcgt ggatcattta catgcagtca accactcaat cgtacaagat cgtatcgaag
     1201 caggtacctt tatggttgct gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta
     1261 tctctgaaca taaccgccca ttgatttcta aattgatcga aatgggtgca gaaatcattg
     1321 aagaagaagg cggagtccgt gtcatcggac caaaacatat cttacctaca gatgtaaaaa
     1381 cgatgcctca tcctggtttc cctacagata tgcaagctca aatgacagct atccaattag
     1441 ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga aaatcgtttc caacatttag
     1501 aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg aaatgtagca atcatggatg
     1561 gaaaccatga attgcaaggt gcagaagtat atgcaacaga cttgcgggca gcagcagcat
     1621 tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt gcgtaacttg aattatctag
     1681 accgtggata ttataatttc catatcaaac tacagcaatt aggtgcagac gttgaacgtg
     1741 tagacatgga tcaaacttct gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct
     1801 gaatgagtaa ccaacgatat atcttattaa ctttgataaa gattttagtg gtgatcttat
     1861 tgcttatcct tctttttgtg gccggaacga tgatcggata tggtgtcatc ggtggcggca
     1921 atccatttaa agtattccag ccaagtttgt ggattcatat tcgagacttt tttcattgat
     1981 aaataagaat cacagtggtt ctagtcgata tgaagtgagc catgaagcag aacatgacaa
     2041 aagaaaacag aagggaacgt tgacgttagt cgcgatccct ttttttagta aaagaaaaga
     2101 aggaatctaa ttgatgaaga agatattgat ttatttagtt agaggatatc agcgctttat
     2161 ttcgcctgca tttccaccta gctgccgtta ttacccaacc tgttccaatt atatgataaa
     2221 agcaattcaa acccatggtg cactaaaagg gacggtaatg gggactgcac ggatcttacg
     2281 ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca ttgacattcc aattaacgcg
     2341 aaataagaaa gataaaaaag aaccagatta taaaaaggtt gtgaaaaata cgagtagcac
     2401 tgagcgataa agaaaaagag gaaaattatt gtcaaagtaa caactccgca actacttata
     2461 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2521 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2581 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2641 cgaaatcgtc aatgtagcag tagccccaac gtatcaagga aaggggattg gcggaaaatt
     2701 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2761 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2821 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     2881 agatcaatta agggatcaag taattttagc aattcactta cctaaaaata gctttaacta
     2941 ataaactttc aattcgagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3001 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3061 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3121 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3181 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3241 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3301 aactctgttt caactcccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3361 attttatgaa ggtgctgccc gtgattatca agatgttgct tttgttgtgg caggaactgg
     3421 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttatggtgg
     3481 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3541 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaattctt ataccggaaa
     3601 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3661 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3721 cgtattaggc ggcggtgttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3781 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3841 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     3901 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     3961 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4021 aaaatgatgt caaaaaaaaa taaagatgtt gaagtgcgta tagaagaagt gaaaaaagat
     4081 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4141 atcttagcct atgggccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4201 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4261 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4321 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4381 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4441 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4501 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4561 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4621 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4681 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4741 ccaggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4801 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4861 ctaggttgaa catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     4921 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     4981 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5041 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5101 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5161 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5221 tacatatgtt gcgcgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5281 aattatggaa tcgcaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5341 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5401 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5461 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5521 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5581 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5641 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5701 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc ttacttagaa
     5761 ataaaagaga atcagaatca cctgttttta tatatgatca gttaccagtt gctcgtgata
     5821 agaaacagga ccctcttcaa attggacttg tccgttcagc agctcaatga tggattcttt
     5881 aaagtggtca gcactttttt catctacagc acagatgacg ctaacttgat cagtatattg
     5941 gatttctttt ataaaaaaat gttggagttc aagataattc tgtaattttc ctagttgcgg
     6001 atacgtgatc atcacagaga tctcctgttg caaggtacct tctacgattc caatgtcaga
     6061 caatgcttga gagacagcat gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt
     6121 tcctccaaaa tatcgagtga ctactgcagc tacattgatc agttgatttt ttttgaggac
     6181 ttccaacatc ggtacgccag ccgttccact tggttctcca tcatcgctgc ttcgctggat
     6241 ttcatttttt tctccaatga tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt
     6301 ttttatttct tgaatgaaac tttttgcttg gtcctctgat tctattcgtc taagagaaca
     6361 gataaagcgt gattttttga tctcaatctc actttgtcca ttttctttta ttgtacgata
     6421 gcgctcgatc atcttgtcac ctcttttttt cattttcttt attcagtata aataaagttc
     6481 taggttgttt caacactgta acggttgcgc aatcgctgta gtatgcgata ataaagacaa
     6541 aggtaggtgg atctggggat gcaggaacga atgaaaaagt acgatgcaat tacgcattat
     6601 ttgaagaaca atggcggctc tcaagtaacg ttgaccttta cccaatttga cgaactgctg
     6661 tttcccagta acggacttcc caaaacagca agggaaagta cagattggtg ggcaaatgat
     6721 tataaacacc ctgaaaaagg tgcctatggc tggataaatg caggctatga agtagttgtc
     6781 atcaatttgg acaaagaata tgtcgtgttc aataaattag tgaaatctag ttggctattt
     6841 gattaaataa accgcgttta gaaaacgttg acaaatttct ttctttttat ataatagagt
     6901 aacagacgcg aagaaaacgt ttgcgtagtt tgttttaaaa aggagagaaa agtatggcta
     6961 aaaaaacaat catgcttgta tgttcggctg gtatgagcac aagtttacta gtaacaaaaa
     7021 tgcaaaaagc tgctgaagca aaaggaatcg actcggatat tttcgctgtg tccgcttctg
     7081 acgcagataa caatcttgca aataaagatg tagatgtact gttattagga cctcaagttc
     7141 gctttatgaa agctgatttt gaaaaacgtc tggaaccaaa aggcattcct ttagacgtca
     7201 tcaatatggc tgattatggt atgatgaatg gcgaaaaagt gttagatcaa gcaatcacgc
     7261 tcataggtga ataaatagaa cagtataact atcgaacaag cgatccaaaa aatagatcgc
     7321 ttgttttttc gtatattttt ttagggcgaa taatatgaat catttttggg gtagaaggct
     7381 tctgacgaga gatattaaag caatagactg tgaggaggta aatttaccaa attatgagaa
     7441 gatcgcagca gtggaacgtt tgggcaactg gattctttgt catcgctgtg gaatgaggac
     7501 gtccgtcatt gatggacagc ttgcagatta cggttatttt tgtacacatt gtctatattt
     7561 agggcgatgc gacactcaac aagatttata tttgtttgat cagcctgaag caaaacctcg
     7621 agaagtcgtc tttttttgga caggacagct tactgaaaaa caaacggaaa tcgcaaagag
     7681 aatactttgc cattcagaaa aaagacatca tcttatttgg gctgtaacag gtgcagggaa
     7741 aacagagatg ctttatccta ttttagtgga aactttaaaa gctggaggaa gagtagcgat
     7801 ttgtacaccg cgagtcgatg tttgtaatga attgttttta cgctatcgtt atgtttttcc
     7861 agaagaaaaa atcacgttgc tccatgggaa tacagcaacg gcttatacct ttacttcttt
     7921 tgttatctgt acgattcatc agctataccg tttttatcgg tcctttgatt taatagtgat
     7981 cgatgagatc gatgcgtttc cttataacgg ggatgcagga ttagctcatg ctgtgcaaac
     8041 agcgattaaa ccagacggac gattcatcta cttaagtgcc acacctgata aaaagttact
     8101 aaaggaaatc aagcagacgt ttgacatcca caaacttgct ttgcgctttc atcggcgttt
     8161 acttcctgaa cccgtcttgg ttttcatgaa taattggcga caaaaatgca agaacaagaa
     8221 gaagataaaa tctttggtgc ggatcattca tcaattaatt aaagaaaacc atatcctttt
     8281 attttgtcca agtatcacga tgatgcatcg tttgaaagcc acacttcaag aggctcttcc
     8341 gagatatgag atcacagatg tttcttcaag agacaatcag cgggcggaaa aagtccagaa
     8401 aatgcgagaa gcaaaatatg acatactgtt aaccacgatg atccttgaac gtggagtcac
     8461 atttgaaaga atatccgtta tcgttttagg agcggatcat ccggttttta ctaaatcttc
     8521 tttggtacaa atcgcaggaa gagccgatcg taaagggcct tatacgaaca gtcaagtata
     8581 ctttttctat gaagaaaaaa ctgcagctat tcgaaaagct tgtcaggaaa tcaaagaaat
     8641 gaatgaagaa gggaagaaga tgctgtgagg tgcagttgct gcagtaaaga tatcgtccaa
     8701 aatttaacat tcagcgagat tattggtgtt tcgaaataca gattacctca gacttgttca
     8761 gtttgtcgcg cacaatttca tttattggaa acaagaggct gttctggctg tcaaaaacca
     8821 atccatttca atctagagag tacgaaaaag aaagtaaagt ctattcccgt ttactgcagt
     8881 gactgtcaag aatggaagaa gaaatatccg acctatgatt ttcagcaccg tgcctttttt
     8941 gtgtacgatg aaaatatgaa ggcctggctc aatcaataca agtttatggg agatatccga
     9001 ctagcaggca cctttgcata taaatggacg cagataaaaa aagaataccc gacatacatc
     9061 tattgtccaa tacctttatc tgaaaaaagg cgaacagaaa gaggattcaa tcaagtaagc
     9121 gagatgttga aagcagcaag aattcctttt cagatgctac tcaaaagaga gaagcatctg
     9181 ctggctcaag caaaaaacac gcgaaaggaa agattggaga tgcctcaacc ttttgaactt
     9241 gcagtcacct tttctaagat acaaaataaa aaaatattga ttattgatga tgtctataca
     9301 acaggacaga ctcttttcca cgcagcagat tgtttgcagg tcgcacagcc gaaaatcatc
     9361 cgaaccattt ctttagcaag atgaattaga tgtggaaatt tgatagcgat ttaatttgca
     9421 aataacctag agttcgatat aatagaatta agaagaggga aagagtggtc cttctccttc
     9481 ttgattgtgg tagacgaaag gggtaatttt tatgtttaga tataatgtac gcggcgaaaa
     9541 tatcgaagta actgaagcga ttcgcgacta cgttgagaaa aaagtaggca aactagaacg
     9601 ctatttcagt gacgcacccg atgcaacggc gcatgtgaac ttaaaagttt atacagaaaa
     9661 aacagcaaaa gtggaagtaa cgatcccatt accttatctt gtattacgtg ccgaagaaac
     9721 ttctccagat ttatacgcaa gtatcgattt ggttgttgac aaattggaac gccaaatccg
     9781 caaattcaaa acaaaaatta atcgtaaatc ccgtgaaacg ggcatgaata ctgcagatgc
     9841 tactgcttta ttcaatgaag aggacgaaaa cgaaaatgat tctgaattag atatcgtacg
     9901 tacgaaacgc ctttcattga aaccaatgga tagtgaagaa gcagtcttac aaatgaacat
     9961 gctgggacat aacttcttta tttttgaaga tgcagaaaca aatggtacaa gtatcgttta
    10021 ccgccgtaaa gatggaaaat acggactgat tgaaacagac tgatcagcct tacttaaata
    10081 acaacgaaaa cttgcagcag ctactgacag ctgccgcaag tttttttgag tttcctcctc
    10141 ttttagatga aatatgaata aattatgaag ttcttacttt aatacgctta agatatttca
    10201 attatctata actaatgata aaatgaaaag taaagtctac atagtctgga taatacacag
    10261 aaggaaaagg agattacaca acgcatggcc aatttgattc gttcacttat cgaaaacgat
    10321 aagaaagaac taaaacgttt agatagcatt gcaaaaaaag ttgaagcata cgctgaccaa
    10381 atggcagcat taactgatga acaattacag gcaaaaactg ctgaattcaa gggcagatac
    10441 caaaaaggag aaacattaga tcaattactt ccggaagctt ttgcagtcgt ccgagaagca
    10501 gcaaaacgtg tattggggtt atatccacac cacgtacaat tgatgggtgg aatcgtgctt
    10561 cacgatggaa atatccctga aatgcgtact ggtgaaggta aaaccttgac cgcaacgatg
    10621 ccagtatatc taaatgctct gactggcgaa ggggtacacg tagttaccgt caatgaatat
    10681 ttagcaaccc gtgactcgac ggaaatgggc gaactttata atttcttagg attaacagtg
    10741 gggttgaata tcaactcaaa atcttcggat gaaaaacgcg aggcttataa ttgtgatatc
    10801 acttatagta cgaataatga attaggattt gactacttga gagacaatat ggtcgtttac
    10861 cgccatcaaa tggtacaacg tccgctgaat tatgccattg tcgatgaagt tgactcaatc
    10921 ttgattgatg aagcgagaac gccgctgatc atttcagggc aagcagaaaa atccacagct
    10981 ttatatacaa gagcagacaa cttcgtgaaa cgtttgaaag aagaagaaga ttataaaatc
    11041 gatgtacaat caaaaacaat cagtttaacc gaagcaggga tcgaaaaagc agaagaaaca
    11101 ttcggtttgg ataacttata cgacattgaa aatactgcat tgacccatca cttggatcaa
    11161 gcattgagag ccaactatat catgctttta gatatcgatt atgttgtcca agacggaaaa
    11221 gtactgattg ttgaccagtt cactggtcgg atcatggatg gacgccgtta ttcagatgga
    11281 cttcaccaag caatcgaagc taaagaaggc gtagagatcg aagacgaaac gaaaaccatg
    11341 gcgacgatca ctttccagaa ctatttccgt atgtacaaga aacttgcggg aatgactggt
    11401 acagctaaaa cagaagaaga agaattcaga gaaatttata acatccaagt ataccagatt
    11461 ccgacaaatc gtccggttat ccgtgatgat cgtccagatt tgctttaccc aacattacaa
    11521 agcaagttcc acgctgtcgt gcaagatatc aaagatcgct accgcaaagg tcaacctgtg
    11581 ttagtcggaa ctgttgcggt tgaaacatct gagttattat cagatatgct gaatcaagaa
    11641 cgtattcctc atgaagtgct gaatgcgaaa aatcacttta aagaagcaga gatcatcatg
    11701 aatgctggtc aaaaaggtgc tgtgacgatt gctaccaaca tggctggtcg gggaacagat
    11761 atcaagttag gacttggggt aagagaactt ggtggtctag cagttatcgg gacagaacga
    11821 catgaatctc gtcgtatcga taaccagctt cgaggacgtg caggacgtca aggagaccct
    11881 ggtatgtcac agttctactt gtcattggaa gatgatttga tgaaacgatt cggttcagaa
    11941 cgaatcaaat ctttcttaga tcggatgaag atcggtgagg aagatgctgt tatccaaagc
    12001 aagatgctga cgaaacaagt agaatctgca caaaaacgtg tagaaggaaa taactatgac
    12061 acacgtaaaa acgtcttaca atacgatgat gtgatgcgtg aacaacgtga agtaatctat
    12121 aaacagcgac aagaagtaat catggaagaa aaaagcttat ccaagccact aatgaacatg
    12181 gtcaaacgga caatcagtcg tgtagtagat gcgcatacac aattagagaa agaaaattgg
    12241 aatttggaaa gtatcatcga ttttgccggc agtactcttg tccatgaaga tagtattact
    12301 cttgcagata tcgaaggaaa aacagctcag gagatcaaag agtatctaaa cgaacgagca
    12361 caagaagtat ttaataccaa agcggctcaa ctaaatggtc cagagcaact gttggaattt
    12421 gaaaaagtcg tgatcttgcg tgttgtggac tctaaatgga cagaccatat tgatgcaatg
    12481 gatcaattac gtcagtcaat cggcttacgt gcttatggac agaacaatcc attagtcgaa
    12541 tatcaaacag aaggctataa gatgtttgaa gatatggtag gcgccatcga gtatgaagtc
    12601 actcgaatct ttatgaaagc tgagatccgt caaaacgtac agcgtgaaca ggtttctcaa
    12661 ggaacagctt ctcactcaga agacggagat gccaaagaaa atagtaatac tagcgcgaaa
    12721 aaacagccaa tccatgtgaa caaggtcgga agaaatgatc cttgtccttg tggaagcggg
    12781 aaaaaatata agaactgtca tggaaaaaat gcaaactaat ttctgacagc aggattggtg
    12841 agacaaattc tttttttaag aattcgtctc accttctttc tgttatttgc tgattctgtt
    12901 agactagata taatgaaaaa agtatagtga aagaaggaaa aaacatggaa atatccgaaa
    12961 ttcgaaatct cctgacagaa atgcaggaaa aggtcacaag cttcaggagg tctctttgac
    13021 ttagaccagc tggaagaaga cattgcggaa gcagaagcaa aaatggctga acctggtttt
    13081 tgggatgata gcgaagctgc tcaaaaagtg atcagtgaaa acaatgcaaa taaagaaact
    13141 tatgatcaat tccattctct tgctgaagaa ctggaagaaa tcgaattgat ggtggagatg
    13201 ttgcaggaag aacctgatgc agccatgcaa gaagaagcag aaacacgtat caatgcgcta
    13261 gatgaaaaaa tgaagacata tgaattatct atgttgttag atggtcctta tgatcgaaac
    13321 aacgccatcg ttgaattgca tccaggggct ggcggaacgg agtcccaaga ttggggcagt
    13381 atgcttttac gtatgtatac acgctgggca gagcagcatg ggtatcaagt agagacacta
    13441 gattatcaag caggtgatga agcaggaatc aagagtgtga ccctactgat caaaggacac
    13501 aacgcatttg gttatctgaa atcagaaaaa ggtgttcatc gccttgtacg tatctcgcct
    13561 tttgactcag cgaaacgacg tcatacttct ttttgttcgg tagatgtgat gccagagctt
    13621 gatgaaacga tcgatataga aatcaatcca gatgatttga aaatcgatac gtaccgagca
    13681 agtggtgcag gtggtcagca catcaataaa acagaatctg ctgtacggat cactcacttg
    13741 cctacaggaa cagtagtagc tagtcaggca caacgttcac aattgaaaaa ccgtgagcaa
    13801 gcgatgggga tgttaaaagc taagctttat caattagaag tggaaaagaa agaacaagaa
    13861 gcagctgcac ttcgaggaga acaaaaagaa atcggctggg gttcacagat ccgttcttat
    13921 gttttccatc catattctat ggtaaaagac catcggacaa acgtagagac aggaaatgtc
    13981 caagcagtta tggacggtga ccttgattta tttattgacg gctatttaaa aatgcatcta
    14041 caataagaac ccattgttaa attgaaataa aattgtaaga ttttgcaagc atgttgaaac
    14101 attgccatgc tataatagct aaagactgaa aaagatatgg agagaacgcc atgattgaaa
    14161 tgaaggatgt aatgaagaag tactcaaatg gtacgaccgc tatccgcaat ctctcaattg
    14221 tcatcgaaca aggagagttt gtctatgtgg ttggtccgtc tggagccggt aaatctacat
    14281 tcatcaaatt gatgtatcga gaagaaaaag cttcaaaagg aactttgaac gtcgcaggtc
    14341 atgatctaat agcaatcaaa aaccgcgaag ttccttatct acgcagagaa atcggcgtgg
    14401 tgttccaaga ctataaatta ttaccaagaa aaacagtata tgaaaatgtt gcgtacgcta
    14461 tgcaagttat cggcagaaaa cctcgggata tcaaaaaacg agtaatggaa gtgctggacc
    14521 ttgttggttt gaaacacaaa gttcgagtct ttcctagcga attatccggt ggggaacagc
    14581 aacgtgtctc tattgctcgg gcaatagtga atacgcctaa agtacttatc gcggatgaac
    14641 cgacaggaaa tctggatcca gaaaactcat gggaaatcat gaaattatta gatcggatca
    14701 atgcccaagg aactactgtc gtgatggcta cacataacag tacgatcgta aatacgattc
    14761 ggcaccgagt aattgctatc gaaaacggcc gcattattcg agatcaagcg gaaggggaat
    14821 atggatacga tgattagaac ctttttccgc catttattag aaagtatcaa gagtttgaaa
    14881 cgtaacggct ggatgacagt tgcttcagtc agtgcggtaa cgatcacatt gactttagtc
    14941 ggtgtattca tggcagttat catgaacgca actaaattag ctcaagatat agaaggaaac
    15001 gttgatgtct ctgtattcgt agatatcggt acaaaagacg aagagatgaa aaagctagaa
    15061 aaagaattga atgacttaga tcatgttaaa aaagttgaat tttcaagcaa agaacaggaa
    15121 ttgaaaaaaa tccaaaacga aatgggtgat tcctggaaat tgtttgaagg tgacaataac
    15181 ccgttatatg atgtgtatgt agtaagtgct actgatcctt cttatacaaa acaagtagca
    15241 gaagaagcag cagatttgaa gaatgtttct cgttctgatt acggtggagc ttcctcagat
    15301 cggattttcc aaatcgctgg tgcagttcgg acatggggat tagttgcagc ggcattgctg
    15361 ctgttcgtag cgatgtttct catttcgaac acgattcgga tcacgatttt gtctagacag
    15421 cgtgaaattc aaatcatgcg tttagtcggt gcaaaaaatg gatatattcg ctggccgttt
    15481 ttccttgaag gtggctggat cggtctgatc ggtgcgattc ttccgatttt gatcatcaca
    15541 tttggttatg catggttttt ccaattgatc aatccatcat tattacgttc ccattattca
    15601 ttgattcatc cacaaaatat cgtttggaaa atcaatcttt taatggtcgg cattggtgtg
    15661 atcattggtt cacttggctc gatcatttct atgagacgtt tcttgaaatt ctaataccac
    15721 aatataaata aaatgagaaa gttggacagt ttcgttccag ctttcttttt ttattggcta
    15781 ggagaataga aggaagcggc ttttttccct ttactttaaa aaacaacttg ggtattctta
    15841 agttggtaga agaagaggtg aagccgtgaa aattatcgtt gacaattttt ttacgatcct
    15901 tttgattatg aatattttgc tttcctttat catcgttttt cgagaaagaa aggaaactgc
    15961 tcaaacatgg gcatgggtgc tcgttttgat gttcattcca gttgtaggat ttattttata
    16021 tattttttta ggaagaggga tttccaaaga gaaaatcttt gatttgaaga tccaagggaa
    16081 aatcggtaag aacctggaaa ttgaagaaga caaacaggca ttgatgcgag ggctttatcc
    16141 tcatccgcct actggacaag tagatgtgaa acaattgatc tatatgctca cggtatttga
    16201 aagtacgctc tatacgacta aaaatgaaat cactttattt acagatggtc gtgaaaaatt
    16261 cgatgcgctg attgaagata tcaagcaggc agaagaccat atccacttcc agtattatat
    16321 ttatcgcagt gatgcattag gtgaagaagt tcgagatgca ttgacagagg cggcaagacg
    16381 aggggtaaaa gtcagagtcc ttcttgatgc atggggttcc acacaagttt cttccagctt
    16441 ttttcagaat ttgaaaaaag caggcggaga agtcgcattt ttctttcctc tatttgttcc
    16501 gtatattaat cctcggatca attatcgcaa tcatcgtaaa atcgtagtta ttgatgggaa
    16561 aatcggatat acaggtgggt tcaatgttgg aaatgaatat ctaggattgg taaagaaatt
    16621 tggttattgg cgagacaatc atttgcgtat ttacggagaa gcggtgtata ccttgcaaaa
    16681 ccgttttttg atggactgga attctcagca tacaaaagaa gtaggctatt ctcccaaatt
    16741 ttttccgtcc attcactcta ctggtgatat agctgttcaa atcgtgacaa gcggaccaga
    16801 taccgaacat gaacaaatca aaatgactta tttgaaaatg atttcgttag ccaaacggga
    16861 gatattgatc caaacgcctt attacatacc ggatggatcg attcatgaag cactgaagtt
    16921 ggctcttctt tcaggcgtaa aagttcatat ccaaatacct aacaaaccag atcatcttct
    16981 cgtttactgg gcaacgtatt ctttcgctgc agagctaatc gagtatggag caaggatcga
    17041 aacatatgag aatggattta ttcatgcaaa gacgatgatt atcgatggtg gcattgtttc
    17101 agttggctca gcaaatatcg atgttcgttc atttcgcttg gactttgagg tcaatacact
    17161 ggtttatgat gaacgaatgg cttcacgtgt aagaaaagct ttttttgaag actcgaaaat
    17221 ttctacgcat ctcacaaaag aaatgtatga aaaccgagga ataatcatca agatgaaaga
    17281 aggattagca agattgattt cgccgctcct ttaaaacata aaaaggacat gagaaccatc
    17341 aacagatgga gatctcgtgt ccttttctaa cggggccatt tctgagagta cgtcagaaat
    17401 ggagaaagcg tctcgcatga gcgaaattaa ctttggggta tctcttgttt tttggggaaa
    17461 gcaagaaata agctaatata tgctattaaa agagacacat ttcaaagcca gtatagcata
    17521 gaaactttta atgagatagt tttttttaca attatgagaa tttattttgt tatttaatga
    17581 ttttgattcg ttttcatcaa gtaatgaaaa tgataaaata aacatacttt aggattaaag
    17641 gagatttcta atgaaaaaac ttaaattatt cttaccaata ataggattag ctattctttt
    17701 atcaggctgt tcaaagtgga ttgatcgagg agaatccatt acggctgttg gctcttctgc
    17761 tttacagcct ttagtagaaa cagttgctga aacttaccag acagaaaatc ctggaaaatt
    17821 catcaatgta caagggggcg gaagcggaac tggtttgtct caagtacagt caggagcagt
    17881 cgacatcgga aactctgatt tgtttgcgga agaaaaatcg gggatcgatg cctcagcatt
    17941 agtcgatcat cgagtagcag ttgttgggat cactcctatt gtgaacaagg atattggcgt
    18001 aaaagacatc agtatggaaa acctgaaaaa actatttaca ggcgagatca aaaactggag
    18061 tgaagtcggt ggaaaagatc agccagtagt tatattgaac cgcgcttcag gaagcggaac
    18121 ccgtagcacg tttgaaaaat gggtattgga cggagaaaca gctgttcagg cacaagaaca
    18181 agattcaagc ggaatggtgc gccagatcgt tgccgacaca cccggtgcaa tcagctatgt
    18241 tgctttttct tatgtttccg atgatgtaga tacgttgaat gttaacggtg tagaaccgac
    18301 agatgaaaat gtgacaacga acaaatggac gatttgggca tatgagcata tgtacacaag
    18361 agatcatcca aaaaaactga caaaagaatt tttagactat atcttatctg atgaagtaca
    18421 agataacatc gttggagaac taggttatat ccctgtttct catatgaaag tcgaacgtga
    18481 ttggcaagga aatatcgtta aagagtaatc tttacacaaa atttacaaac ttagctaaac
    18541 ttttacatgt tattaaaacc aaattgatgt tcaatttgta cactgagtga gtatgttaaa
    18601 cctgattaag ggggagtcat ctgtggaaga tgtgaaaaaa gtattattaa caaaatcaaa
    18661 acgttcaaaa atggaacagc gtggaaaatt catcagtttt ttatgtatcg cgctgatcgt
    18721 gttggttgta ttatctattt tttattttgt agctagtaaa ggattggcca ccttttttac
    18781 tgataagatc aatgtatttg attttctgtt tggtacagat tggaatccaa gccaaatcgg
    18841 agcaaatggg aaaccaatgg taggggcatt gcctatgatc acaggttcgt ttattgtgac
    18901 ctttttatct gctatcgttg ccacgccatt tgccattggt gcagcagtat tcatgacgga
    18961 gatctctcct aaaaacggaa cgaagatctt acagccggtc atcgagctgc ttgtaggtat
    19021 tccttctgtc gtttatggtt ttatcggttt atcagttatc gtgccttttg tcagaagtat
    19081 ttttggcggg actgggtttg gtatcttagc tggtacattt gtgttgttcg ttatgatctt
    19141 gccgactgtc acaacgatga ctgttgatgc attaaaggca gtgccacggc actatcggga
    19201 agcttcatta gcgcttggtg ccacaagatg gcaaacaatc tacaaagtcg tgctacgagc
    19261 agccgtgccc gggattttaa cagcagtcgt ttttggtatg gctcgtgcgt ttggtgaagc
    19321 cttagctatc caaatggtca tcggtaatgc agcattgatg ccaacaggtc ttactactcc
    19381 tgcttctaca ttgacgtcca tcttaacaat gggaatcgga aatacaatca tgggaacagt
    19441 tgaaaataat gtgttatggt cattagcgct gatcttgcta ttgatgtcat tattctttaa
    19501 tatcgtgatc cgtatgattg ggaagaaagg agagctgaaa taatgaacgc aaaacgctca
    19561 gataaaattg ctacaggtgt tttatatata gtttcgggga tcatcgtatt gattttagca
    19621 gctttactac tttatatctt agttcgggga ataccgcaca tttcatggtc cttcttgacc
    19681 gaaccttcca aagcctacca agaaggcggt ggaatcggga tccagctatt taactcgatt
    19741 tatttgcttt tgatcacgat gatcatcagt tttcctattt ctttaggtgc gggtatctat
    19801 ctttcagaat atgctggaaa aaactggcta acagatgtga ttcgcacgtc gattgaaatc
    19861 ttgagctcgt tgccttctgt cgttgtcggt ttattcggtt tcttggtttt cgttattcaa
    19921 ttccagtatg gtttctcgat tatttctggt gcattggctt tgactgtatt caacttgcct
    19981 cttttgacta gaacagttga ggagtcttta caagcggtcc attacacaca acgagaagca
    20041 ggattggcct taggtttgtc acgctgggaa acagtgataa aagtggtggt tccagaagcg
    20101 acaccaggga ttttgactgg tgtgatccta agttctggaa gaatttttgg tgaagcagct
    20161 gcattgatct atacggctgg acaaagtgca cctgcgttag attttacgaa ctggaatcca
    20221 ttaagtgttt caagcccgat cagcattttc cgtcaagctg aaacattagc tgtccatatt
    20281 tggaagatca atacagaagg cacgatgcct gatggtgttt ctgtttcggc tggcgcttct
    20341 gccgtgttga ttattgctgt tttactgttc aacttcggcg ctcgtgcgat tggcaaacga
    20401 ttataccgaa aaatgacttc agcctaagga gaagaagcaa aatgaaaaaa tataactgga
    20461 atgaaacaaa tgtcatcacc atgccaaaag agaaagaagt agcactatat acggatgatc
    20521 tacatgtctg gtatggcgac aatgaagcaa tcaaaggagt ggatctggaa tttgaaaaaa
    20581 ataagatcac tgcactgatt ggtccttccg gctgcggaaa atctacgtat cttcgttcgt
    20641 tgaatcgaat gaatgatggg atcgctaata cgaaaatcac tgggaaaatc atgtatcaag
    20701 gcgtagatat taatgcgcct caagtggatg tttatgagat gcgcaaacgg attggcatgg
    20761 tttttcaacg tcctaatccg ttcagcaagt cgatttatga caatattaca tttgctttga
    20821 aacagcacgg cgaaaaaaac aaaaagaaat tagatgaaat cgttgaaaca agcttgaaac
    20881 aagctgcctt gtgggaccaa gtaaaagaca gcttggacaa aagtgccttg gctttatctg
    20941 gcgggcaaca gcaacgttta tgtattgctc gtgcgatcgc gatgaaacct gatatcttgc
    21001 tgctagacga gccggcaagt gctttggacc ctatttcgac aggaacggtt gaagaaacac
    21061 ttgtaaactt gaaagaagac tatacgatca tcatcgtgac gcataacatg caacaagcag
    21121 ctcgtatcag cgactatact gcctttttct atttaggaaa agtaatggaa tatgacaaaa
    21181 ctaacaagat atttaccaga ccaaaaattc aggcaaccga agattatgtg tccggtcatt
    21241 ttggttaaga cggaggcctc aacatgacaa aagagattat ttcatctaaa gatcttcatc
    21301 tgtattatgg aaagaaagaa gcactaaaag ggatcgatct aagcttcaat caaggggaaa
    21361 tcactgcgat gatcggtcct tctggttgcg gaaaatccac ttatctgcgt tctttgaacc
    21421 ggatgaatga cctgattccg aatgtaacga tcaccggaag tgttttatat aaagacaaag
    21481 acatctatgg tccaaaaaca gatgttgttg aactaagaaa agaaatcggc atggtattcc
    21541 agcagccaaa cccatttcct ttttctatct atgaaaatgt catctatgga ttgaaattaa
    21601 aaggggaaaa agataaaaaa gtccttgatc aagtagttga agaaagcctg aaggcagcgt
    21661 ctgtttggga tgatgtgaaa gacaaattgc ataaaagtgc tttatcttta tccggtgggc
    21721 agcagcagcg tgtatgtatc gcacgtgttt tggcagttaa tccggaaatc atcttattgg
    21781 atgaaccaac aagtgcgctt gatcctgttt ctactgggaa aatcgaaagt atgctgttag
    21841 aattaagaga gcggtatacg atgatcatcg tgacccataa tatgtctcaa gcttcacgta
    21901 tttcagataa gacggcattc tttttagatg gtcacttgat cgaatacaat gatacgaaga
    21961 agatattcat gaatccagaa aaacaagaga cagaagatta tatttcaggt cgatttggat
    22021 aaggaggaaa cggaatgcta cgtacacaat ttgaagaaga attgctgaat ctccataatc
    22081 agttctacga aatggggatg atggtgagca gcgccgtgca caagtcagtt cgtgcataca
    22141 tcaaacacga taaaatctta gcccaagaag ttatcgaaaa cgatataaat atcaataaca
    22201 tggaaacacg cttggagaag aaaagttttg aaatgatcgc attgcaacag ccagttacaa
    22261 ctgatttgcg tatgatcatt acggtcatga aagctagctc ggatttagaa cgtatggccg
    22321 atcatgcggt gtctgttgct aaatccacga ttcgcgtaaa agggcagacg agaataccgg
    22381 aaatcgaaaa agagatctcc gatatgtccg attatgtgaa aaaaatggtg gacaacgtcc
    22441 tagttgctta tgtcaaaaca gacgaaaaag acgcacgtac gatcgccaat atggatcaaa
    22501 gagtcaatga ctatttcaat cgaatctata atgcaacaat caaaaatatg caggaaaatc
    22561 ctgagacagt catcagtgga acagactact tgaatgttgc cagttatcta gaacggatcg
    22621 gagactatgt gacaaacatc tgtgaatgga tcgtctactt ggctacaggg aaaatcactg
    22681 agttaaatac gaaccacaat gagattttct aaactgaagc tgtgattatg ccgtttgttt
    22741 aggaaaagag gttgtgaaat cagcggttgt gaaaaagctg ttctgcatca agtaataaga
    22801 acagtcaaac aaaaaatagc tcctcatatt tttcgtttgg ctggacttat taccgcagat
    22861 gcaagctttt gaacaccgtt tattcgggaa agggtttgtg acaaaacatg tcacaaaccc
    22921 ttttcatcat ttcatagaaa ggataaagaa tgcaaaaaaa aattagcatc atcactatat
    22981 tttttatttg tgtgcttact tcatgggtta ttcagcatca agccgcttta tatgaagtac
    23041 ctgtcatcga gatagaaaaa gtacgaataa aagaggatca tcaattgatt acaggaaaac
    23101 tgatgaacac ggatcaaaaa ggagaatcga tttatttatc ggttccttat caaaaaaatc
    23161 aaatagaaac agcaaatata aaagcgagac aaatgtatct agtccaaatg catggagatg
    23221 aatggcagct agtagcaaaa aaaaatgatg gctggctttt cttcttcaca agtatcttca
    23281 ttggcgccat gttgcttatt ggtggaaaac agggtctatt tgctttagga agtctcatca
    23341 tcaatatcgt tttactttta cttttgttgc tcatctttac taaaacagaa gggatttctc
    23401 tattaaatat atctatcctg ttcgtcgtta tagggatgat tattagcata ttggctttag
    23461 atggatggaa tagaagcagt ataatcaaaa tttcagctgc agttacgagt gtttttttag
    23521 cattttttat ttgtcttttg acaatgaatc attggaaaga ccaaggactg cgctatgagg
    23581 aactgaatta tctgacacga ccgtatcgtt ctgtttttct ttctagcgta ctgattggaa
    23641 cagctggagg aacactcgat accgttatca cagtcattgc gacattagaa gaattgacta
    23701 agcgacaacc agaaataaca gcgaaacagt tatggctttc aggaaggcaa gtgggtcgag
    23761 atgtgattgg ctcgatgacc aatatccttt tgttcgtcta tatcagtggg tcagttccat
    23821 cgcttctttt atatttagga aatcaatggt cgttcaaaga aacgatagaa cagcatttat
    23881 cattggaatt tttacgcgtc attgctggca gcttaggaat agtattatcg atccctatct
    23941 cggtcctctt ttttctgact gtaaggaggc tgaaacgatg aatgtactta ttatacttgt
    24001 tgggatttta gcaatcagcg tgctacttat tggcggtacg caaggtatgt atattctttt
    24061 aggcttattc atcaatttag ggatcttttt cctgttgtta ttcggttatc atcagaagtg
    24121 gccgatactg gcattgtcgg tcataggatt tttattgatt gctgtggtta tcttattttt
    24181 tatcaacggt tataatctaa aaatgcgtgc agcttttgtg agtatactga tctttttatt
    24241 ttgtttccta ctattgcttc ctatcactga ttttttagca atccaaggtt ttacatcggt
    24301 agaactagaa gaattatctg gcttagataa gactttagcg attgatttta gattacttac
    24361 gagatcgttg cttctgatta gtcttagtgg tgctgtttta gatgcgagtg tagcaatttc
    24421 tagtgggaca ttcgaagtat atcaggcaaa tccgcaatta tctttttacc aattgcgcca
    24481 ttctagtttc gctattgcta aaaaaatatt ggcgtcaaca gtaatgacac ttctttttgc
    24541 attcatggga agttctttag cgttgatcct ctggtttatt gatttagaca ttccttttca
    24601 gcaagtgatc aatgaaaaat catttgttct agaatatacg atggctattc ttaccacatt
    24661 gtccgcacta cttgttcttc ctttaacctg cgtgactaca gcatatctct ttacaaaaaa
    24721 gaaagaacaa ctcaagatgg agtaaaagtt acaacttaag tcctatgaca tttttactga
    24781 atcagtgcat aatatggatg taaggaaaag cttgcaaaca attttgctta aggaggcaat
    24841 ttccatgaaa gaaagagaac gtattttaga tttagtgaaa aaaggaatcc tttcgactga
    24901 agaaggctta gatttattag aaagcatggc aactgaaaaa gacgaaaagc aaatcaaaaa
    24961 agaagcagac aaggtaactg ctagtcataa agaaaaagat caggcaagtc aattgatcga
    25021 taaacttgaa aacggcgaag aagaaatttc tgagccagtt gatccaaagg aaagagaaag
    25081 acaagatcaa gaaaacttag aaaagatctt agatgaacta gcaactgaag cgaataaaac
    25141 ttcggcgcgt ctagatgaag taaatgctca attcgctgac aataaggcag cacgcaatga
    25201 gaaacaggaa gcattgatgc agctgaatac aaaagaagaa ttaggcgagt tgacagaaga
    25261 agaattagca cagcgtcaga cgttagaagc agaaatcaaa gaattagaag ctagtggcga
    25321 tacactgtta gaagaacaat tgaaattaga agcagaatta aaagatatcc gtaagaatca
    25381 atggtctgag aaaaaagaaa cgtttactga taagtttgaa ttgccagatg attggaaaga
    25441 tcaagcaaca gatacactga atcaagtagg cgaaaaaatg tcagaagctg gatcacagtt
    25501 aggcaaattc ttgaagaaaa cattccaaac tgtttcagaa acagtgaatg acaacatgga
    25561 atggaaagat gtcagcttac gtgtccctgg gattgcgaca acgaaatttg agcatgaatt
    25621 ttactatgaa gctcctgcag caagtatcct tgatatcaag gcagcaaacg gaaacgtgac
    25681 gttaaaaacg tgggacagca acgatgtgaa agttgaagct aagatcaaac tttacggaaa
    25741 aatgggtgct gaaccatttg aagcattctc tgaacggagc cagattgagg ttaatgaaga
    25801 tcatatctcc ttccaaattc caaataaacg tgtgcgtgca gaccttgttt tctacttacc
    25861 taaacgagta tacgaccacg cagctattaa acttctaaat ggcaacatca tgattgaaac
    25921 attggaagct aaagatattt atacaaaatc tacgaatggt aacatcatcg tggaccaatt
    25981 aactgcaacg atgctggaag tagaaggtgt aaacggcaat atcgatattc gaaacgggaa
    26041 catcttagat tctattatcg aaacagtaaa tggtacagtg acatttggtg cgacagcaga
    26101 aaacctttct gtgtctttgg taaatggtga tgtacgtctt acgattaaag aagataattt
    26161 gaaaaaagta gaagcaagtt cagtgaacgg aaatgtcaaa gtcgctttac cagatggcat
    26221 cggtttggaa ggacatgcta aaacaagtct tggaagtatc aacagccgtc tgtccaatta
    26281 cgaagtagtt cgtgagaaaa aagaacggac aaaccaaatg ttgcaattcc gtcgtgtttc
    26341 agatggtgaa atcgcgcaag tgcaactttc aacgacaaca ggaagtatct atttaaaaga
    26401 tacagataaa taaagaggtt gtgaaagaga tgttcagcct tgagcaataa gaagcgattt
    26461 tgtaaaatag cttcccctat tttacaaaat tgtgccttat tgccgatagt ctatctcttg
    26521 aacaccgttt accaagagat tatgaacctg ccaattatcg ccgagtcaca aggaataatt
    26581 tcagaaaaag ctcgtcacgt tttatgaata tggtaatttg tgaccgagaa ttttgcagaa
    26641 agacaccgat taagaagaag gttgtcacaa cgattttctt catttaaaat agtagaacag
    26701 aggtgagaca tgatgaaaaa aaagttgaca aaatctaata aaaatgttgt tttgacaggg
    26761 actttagcag gaataggaga atacatcggg attgatccga ctgttatccg tgtgctttat
    26821 gtattcctga gcttagttgc ttttggaagt ccaattattt tatacatttt attagctttg
    26881 attatcccat ctgcgcgttc tgcacgaaca aactatggac ataacaatgc atattatgaa
    26941 aaaaacaatt atcgtgaaca aactcgtgaa caaacaaaaa aacgcaaaga agcggaaaaa
    27001 atcgatgatg acgaatggag tgacttttaa tgtcgtactt tcaacgtatt ttagttaata
    27061 cgttaacatt catatcattg gctgttcttt ttcctgcgat ggtccatgtg agcagtattt
    27121 ggacggccgt tcttgccagc ttcgtattgt ctgtgttgaa tatgtttgtc aaaccgattt
    27181 tgacgatact gtccctgccc tttacattag tcacattggg attgtttacg tttgttatca
    27241 atgcagcgat tcttaaaatg acctcctttt ttgtgggagc agaacatttt agtttttctt
    27301 cattcggtgc agcgttgtta gtagctatct tgatgtcgct tgtcaatgta attgtcagcg
    27361 aacataacag tagaaaataa aagaaagctg tgccgaacta tcggcgcagt ttttttattt
    27421 agaatcagga atgcgttttc tattacattg gtaattaaat aaaaacgttt tttttaattg
    27481 gtagtacttt tggctagaca atgataaaat gatagagaac actctaatag aaatgaggta
    27541 gcatgaatgt cagaagttgt aaaagttagc caattagtga aaaaattatc tttggaaatc
    27601 gtgacaggcg acgagaaaag cttagaccgt gtcatcgtaa ctggggacat ctcacgccca
    27661 ggactagagt tgactggtta ttttaattat tattcccata atcgtttaca gctatttggc
    27721 agtaaagaaa tcagttttgc ggaacggatg atcccagaag agcgtttgat catcatgaga
    27781 agattatgta gtgaagatat gcccgcattt attatttcaa gaggattacc agctccagaa
    27841 gaaatgatcc aggcagcaaa tgaaaatggg atagctgtac tgcgttctcc catctcaact
    27901 tctcgtttat taggagaatt atccagttat ttagatggtc gccttgcccc tcgaacaagt
    27961 gtccacggtg ttttagtgga tgtttacgga ttaggtgtac tgattcaagg tgacagtggg
    28021 ataggaaaaa gtgaaacagc gttggagttg atcaaacgcg gccatcgatt gatcgcagac
    28081 gatcgagtag atgtttatca gcaagatgaa ttaacggtga tcggagaacc gcctaaaatc
    28141 ctggaacatc tgattgaaat ccgaggaatc gggatcattg atgtaatgaa tctttttggt
    28201 gcgagtgcgg tacgtggctc tatgcaagtc cagttggctg tttatctgga agcatgggca
    28261 aaagataaga aatacgaccg tctgggctct gaagacacga ccgttgaaat cgcggaagtg
    28321 ggcattccac aaataaaaat ccctgtcaaa acaggacgaa acgttgcaat catcattgaa
    28381 gtagccgcga tgaatttccg cgcacgtaca atgggctttg acgcaacgaa aacatttgaa
    28441 gaaagattaa gtcgcttgat tgaagaaaac tcaggcaacg actagcaagg agtgacaata
    28501 tgttagcaca aatcaatcga gttgcttttg agcttgtagg gattcctatc tactggtatg
    28561 cattgatcat cgtatcaggt atcattatcg ctatgtggct tagcagcaga gaggctgttc
    28621 gggtaggatt aaaagcagat gatgtgacag attttatgtt gtggggattg cctatctcca
    28681 ttattggcgc tcgcttatat tatgttttat ttgatcttcc ccagtatata gctgatccaa
    28741 tccaaatatt caatatccgt tcaggaggct tagctattta tggcggactg attgcaggcg
    28801 cgatcacgct gtattttttt actaaatatc attttatttc tttgtggact tttttagata
    28861 tcgctgcacc aagtgtatta ttagcacagg caatcggtcg ttggggaaat ttcatgaacc
    28921 acgaagcata tggaccagac acgacgcgaa gcttcttaga aagtctgcat ttaccgcaat
    28981 tcatcattga taatatgtat atcgaaggga tctatcgtca accaacattt ctttatgaat
    29041 cactttggag tttgattgga tttattttgc ttttgttttt acgaaagaaa ccacaccttt
    29101 tgaaaaaagg cgaagtcctt ttatgttatc taatgtggta tagtttcggg cgtttcttta
    29161 ttgaaggatt acgtacagac agtctttact ttttaggtgt gatccgtatt tctcaattat
    29221 tatctgctgt gttatttgtc ggtacattga ttctatttat ttggcgcaga aaaaaaggaa
    29281 atttaccgga ttatgaccgc tcattaggaa aaaatcaaca aattatctga tttttagagc
    29341 gttaaaaatg aaaaaaattt caggagtggt aaaatgaatt atagagtagc ggttttagga
    29401 ccaggctctt ggggtactgc tttggcacaa gtcctcgccg aaaacggaca tgacgttcgg
    29461 atttggggac atcgtgcttc acaagtagaa gaaatcaaca cccaacacac gaatcaacgt
    29521 tatttaccag atcattatct acccgattcc atccaagcat tcaccaatat ggaagatgca
    29581 gtaaaagacg cagatgcggt gctattcgtc attccaacga aagcaatacg ttctgttgca
    29641 aaagaactag tgcctaaatt gaatacaaag ccagtgatca tccatgcaag taaaggatta
    29701 gaacagggaa cacataaaag gatctctgac atcttgttag aggaaatccc agcagaaaaa
    29761 agaaaagctg ttgttgttct ttctggacca agccatgcag aagaagtagc aaaacatgac
    29821 atcactacga tcacagctgc aagtacagat gcaaaagcag caaaatatgt acaagagctg
    29881 ttcatgaata attattttcg gatctatacc aatcctgatg tgatcggtgt agagatgggg
    29941 gcagctttga aaaatattat tgctattggt gctggcgcta ttcacggctt agggtttggc
    30001 gataatgcaa aggcagcaat catgacgcgc ggattagctg agatcagccg tttaggtgta
    30061 gcaatgggtg ccaacccgct gacctttatc ggattaagcg gaataggcga tctagtcgtt
    30121 acttgcacaa gtgttcattc taggaactgg cgcgcaggca acttgttagg acaagggcag
    30181 cccctagaag aggtgctagc caatatggga atggtcgttg aaggtgtgaa tactacccaa
    30241 gcagcgatgg aactagccca aatgatggaa atcgaaatgc ccatcactca aacaatctat
    30301 gaagtgctgt atgaacaaaa agaaatcaaa acagccgcaa aagaaatcat gttacgtgat
    30361 ggaaaaaaag aaaatgaatt ctcattaaca attttttgaa ggagcgaatg tatatgaaag
    30421 ttaaaaaagc agttattcca gcagcaggat taggaacaag atttttacca gcaacaaaag
    30481 ctatggcaaa ggaaatgttg ccaattgttg ataaaccaac aatccagttc atcgttgaag
    30541 aagcgttgaa atcaggtatc gaagacatct tgatcgttac aggaaaagct aaacgaccaa
    30601 tcgaagatca ctttgattca aatattgaat tagaaacaaa cctaagtgaa aaaggaaaga
    30661 ccgaattatt gaaattagta gaagaaacga cagatgtcaa cttgcatttc atccgtcaat
    30721 ctcatccaaa gggtttagga catgccgttc ttcaagcaag agcctttatt ggaaatgaac
    30781 catttgtcgt tatgctaggc gatgatataa tggaagacga agtaccattg acacagcaat
    30841 taatcgatga ttacgaacgt actcatgctt ctacgatcgc cgttatgcaa gttcctcatg
    30901 atgaaacttc aaaatacgga attatcaatc caggagaagt attggaagat gggttataca
    30961 atgtcaaaaa ctttgttgaa aaaccagatc caagcaaagc accaagtgat ttagctatta
    31021 ttggacgtta cttattgact ccagaaattt ttgatgtatt gtccgagcaa caaccaggag
    31081 ccggaaatga aatccaacta actgacgcaa tcgatacatt gaataaaaca caacgcgtat
    31141 ttgcccgtaa attcacaggt aaacgttacg atgtcggtga caaatttggt tttatgaaaa
    31201 caagtattga atatggtcta acacatccag aagtaggtgc acctttacgt gagtacatcc
    31261 tgtctttagg taaaacatta gaagcagaag gaagcaagat cgatcataat ccaaaaggaa
    31321 taacagaaat caaagaagaa aagaaaaaat aacccttttt tctaacgagc ttcagctgct
    31381 aattgaataa aaagtagttg aagctcgttt ttatttgttt aaaaaacacg aaaatgctat
    31441 ccttatagaa aagagagaca agaagggagt ttgatcatgt caggaggaga aattgcagga
    31501 ttgatcgcag caatcgcctt tgcgatactt gtcgttttta tcgttcgtgt gttgttgcaa
    31561 gtttctaaaa ctttagaaaa agtagatcag actgtagcag aagcaaatac gacgatcgaa
    31621 atcgtcacaa aagacgtaga tcttttgtct agacaagtag aaggcttact ggtcaaaagt
    31681 aatgaactgc tcttggatat caatggaaaa gtcgcaacga tcgatccatt gttcacagca
    31741 gttgctgatt taagtgaaag tgtatcagaa cttaatcatt ctagtaaaaa catcgcgacg
    31801 aaagtcggcg gaatcggtaa aacgacagct aaagcgacgg ttgccggaaa agtcggtggg
    31861 acagcgatga aattttttaa aaacaaaaaa catactgaaa cgacaggagg aaaataaaaa
    31921 tggctaaaaa aggtggattt ttattaggtg cagtagtcgg aggcacagcc gcagcaatcg
    31981 ccgcgttatt gttagcacca aaatctggta aagaacttcg ggatgaatta gctgcccaag
    32041 cggatgattt gatggatatg gcttcagatt acacagatat ggcgaaagaa aaatcgactg
    32101 agttaacagg tattgcaaaa gaaaaagcgc aagatctttc tcaacaagca ggtgatctag
    32161 caggtagtgt caaacaaaaa gtaagtgaat cagcagatga agcaggaagt gaatctgacg
    32221 atatcttgtt aaatcttaaa gaacaatcag ctgacttatc taatcgtttc aaaaaaacgg
    32281 cagaagatat gaaaaaacct gcagatgaat taggaagtat tgctaaagat acttcagaag
    32341 atatcatgat tgatgtaaaa gacgctgctg gtaaagcagg agatactgtc aatgaaggaa
    32401 tgtcagaagc aaaaccagtt gcagatgact caaaagaaat gatgaaaatg gcaaaagaag
    32461 atgcgaaaga agctaaaaaa gaaataaaag atacaatgac agattcatct acaaatcact
    32521 aaaatcacaa atttatagaa taaaaaggtg ggagcggact agctctcacc ttttttactc
    32581 ttatttttct aaaacaagta attcttttgg tgtagtcgtg aatggcacac agccatcgct
    32641 tgtcacatat acacagtctt cgatacgtac ccctactttt tcaggaatat agattcctgg
    32701 ttcaagagag aagcacatcc cttcttcgat tactaagtca tttccttcta caagggaagg
    32761 gaattcgtgg acggttgttc cgatcccgtg acctaaacgg tgattgaaat attcgccgta
    32821 gccatagctg ttgatcacgt ttcgtgcgat ttgatcaagt tcacctgctg tcacacctgg
    32881 acggacggct tcttgtgcgg caagctgtgc ttcaagagtg atgttgtaga ttttttcttg
    32941 gaagtcggtt ggtttttgat aagcaattgt acgagtagca tcactgcaat agccattcca
    33001 aacaacgcca agatcgaata acacaagttc attcggtgaa atcttcgtat ttcctggtgt
    33061 accatgaggg cttgcagcat ttgctcctgc aaggactaat gtgtcgaaag acatttgtga
    33121 aacaccttgt tttttcaatt ggtattcaat ttctgcaatg atcgcttgtt cagtcacgcc
    33181 ttctttcact gctttaaagc caatctcaaa tgcaacatcg gcccatttac cagcttcgat
    33241 cagtttgtct ttttcctcta gagttttgat cagttgtaga cgttggatga tggaagttag
    33301 atcagtgtaa gaatccgttc ccgtcaagat atcagagata gcatcgaagc gctcgacagt
    33361 caaggcgttc ttttcaatcc ctacattgcc aggctgacca tagcgagcac gaagttcttt
    33421 tccgatgatc tcccaagggt tttcgctgtc taaatagcca cggacatcat acgcccaact
    33481 actgttttga gcatcttcaa cttccaaagc aggagtgaaa aggaaaggat cttgttcaag
    33541 agggataaaa agagctagta cacgctcatg aggatcactt tcgtatccgg aaaagtaagc
    33601 gatgtggcca gggtcgctga tataagccaa ttcgacttgg tgttgtgcca tccattgacg
    33661 tagttcattg atttttacgt tattcatttg gcaacctact ttctaaatta attttgtatt
    33721 caataattgt accactgatt tattaaaaga ccaacgttct aaaaactgaa aaaagtaaaa
    33781 attttcatga aaacagagat aaaacggttg caattcttga gattatttga tattctattt
    33841 tagaaatgta agacgtattt tcagaaaaca tataaaatat gaataggaga acacaaatgg
    33901 aaaagcaaac aatcactatc tatgatgtag cgagagaggc aaatgtttcg atggctactg
    33961 tttcacgtgt cgtaaatggc aatccaaacg ttaaaccagc aacaagaaaa aaagtcttgg
    34021 aagttatcga tcgcttggat tatcgtccaa acgcagttgc gcgtggcttg gcaagtaaga
    34081 aaacaacaac agttggtgta atcatccctg atgtcagcaa tatgttcttt gcttctttag
    34141 cacgtggtat cgatgatgtg gcaacaatgt acaaatacaa tattatctta gcaaattcag
    34201 atggcaacga ccaaaaagaa gtcaatgtat tgaataactt actggctaag caagtggacg
    34261 gcgtgatctt catgggtcac catatcacag acgaaatccg tggagaattt tcacgttcaa
    34321 aaactcctgt tgtattagct ggctctattg atccagatga acaagtaggt agcgtaaaca
    34381 ttgattatgt atccgcaaca aaagatgcag taaacaaatt ggcaaaaagc ggcaataaaa
    34441 aaatcgcttt tgtcagtggt gcgttgatcg atcccatcaa tggacaaaat cgtctgaaag
    34501 gctataaaga agcattaagc gaaaataacc taccatatag cgaaggattg atctttgaag
    34561 cacaatacaa cttcaaagat ggtctatctc tagtcgatcg gatccataat agcggtgcaa
    34621 cagctgtcta tgtttcagat gatgaattag ccatcggtat tttggatggt ttattagacc
    34681 gtggcgtgaa agtaccggaa gaattcgaaa tcatcacaag taacaattca ctactgacag
    34741 aagtagctcg tcctcgttta acaagtatca cacaaccatt atacgattta ggggcggtat
    34801 ctatgcgcct attgacgaaa atgatgaata aagaagaagt cgaagaaaaa acgattatct
    34861 tgccttatgg aatcgaagaa aaaggatcta caaaataata aaaggacaac cattcagagg
    34921 ttgtgtgcct gccgtttaac tctgcgttac aaggagcaat ttcaaaaaac agcatctcat
    34981 gtttgatgaa tattgtgact cgtgattcgg agttggcagg agaacaccgt ttatttggga
    35041 aaaggggtta tgacaaaatt ttgttataat cctttttttg tgtcttaaaa aagagagaaa
    35101 gtggttgaaa ttacatttat cgtatataaa acaatccgtg tatagatgct gcattttgtt
    35161 caccaccatc aaaaaaataa gggactgtga caatactatt gtcacaatcc cttattactg
    35221 tgtattctat taaatcaatc atctttctca tctgattctt tagttgcttg attcgctctt
    35281 gcataagctg aagcggtgtt ccagtaatct gtatagtttt catcggtacc gccaacgcca
    35341 aatttaaagg cgcttttctt cggtccattt ttcgcccata gcgattcaac tgtttttcct
    35401 ggtgtttgga tggatttttt attgacagta acttttccag gtgtttgacc agtaaatcca
    35461 gatacttttt tcttcatcac atcagatgat aattcgaatt tctcatcagt gccaaaaatg
    35521 tcaggttttg cttggtaagc ttgattgatc agattggcaa gataattagc cgaacgtatc
    35581 cttgctttgc tgtccattcc agtattgtca tcgtgccctg cccagctact gatggtaata
    35641 gacggagtag agacaattag ccatgaatct cggtattcat tggtagaacc agtttttccg
    35701 acccaatctg cttttcctag atttccgttt aagcttgaga tggcatcttt gaatggtgta
    35761 gtgatttttg cattgatcac actacgcatc atgtcattca tgatcgatgc cgttgcttcc
    35821 gaatagatcc ggacagagtt gctttcgtgt ttataaatta catttcctgc gttatctgtg
    35881 atggaatcga tgatatagcc ttcttcatag acgccgccgt ttgctaaagc ctgaaatccg
    35941 ttggtctgtt gaagcgtcgt gacatctact gtacctaaag gagcagattc aacgccccaa
    36001 ttgtcatttg ccgggtagtt catctttgcc aagtagtgct cgtaagcata ttgtttcgat
    36061 ccaccggaat tcaacacatc ttgatataag tgataagccg ggatattgtt ggaccattct
    36121 agtgactcac ggacggtttg gaaggtgttc gatccttcgt tagtagcatt gacgattttc
    36181 tcgccagcat tttctccttc ttgccaagtt gttgcataat ctgatacacg ggattctgat
    36241 ccgataagcc ccatgtcgat tgcaggtcca taaacaagaa ctggtttgat tgatgagcca
    36301 gcttgacgtt ctgtatcgaa ggcatggtta ttttgattct gactgtaatt ccgtccgcca
    36361 acgaatccgt agatgcggcc agttctgtta tccatcaata catttccggt ttctacttga
    36421 ctgccagcac catcatctaa catgtatcca taattttcaa cgccattttg caatgcagca
    36481 tagacatctt tatcgattgt cgaatggatt gtatatcctt tattttggat cgtttgctgt
    36541 gccttttgat aataagcgtc actgaccgat gaatcagaca tatcagcgtt gtctttttca
    36601 gccaattgtt gtgcaatgat tcttgttgct tcattcatca cagtataata caagaattct
    36661 ctgtcagtct gttctgcgat ttgttgtggt agaaagtctt ttgtaaggtc ataggctttt
    36721 gcttcttcgt attgttcttt cgtaatttgg ccttcacgat acatactgaa taaaacaaaa
    36781 tcttttctgg caaggccggc agaaagatct tcttttagcg cgcctgtgtt cgtgtatgga
    36841 ctatacgtga tcgggctttg gggtaatcca gcgatataag cagcttgcgg cagcgtcaca
    36901 tcttttgcat ctacaccaaa gattcctttt gcagcttcct ggactccagc aatgttttgt
    36961 cccttattat tacgaccaaa tggtgagaca ttcaaatacg tagcaatgat ctcatctttt
    37021 gaaaagtatt tttctacttg tgcagaaaga atgatctcgt ttgctttacg tttgaatgtt
    37081 gtttcatctg taaggatctg ctgtttgact aattgctgtg tcaaagttga tccaccagaa
    37141 gagccaatac cagtagcttc agatactaat gctcgtaaaa cagctttagg aacgtaacct
    37201 tggtgtttat cgaagtattc atcctctgtg ctgataattg cagttttcaa taaaggtgaa
    37261 atcttatcag atgaaatagt cgtgcgcatc agatctgtct ggatttttga tatctctgta
    37321 ttatctgcat aaacaatctt tgacgtttct gtaatgtttc ctagttctgt ctgcagtgct
    37381 tttttagtcg gcaattgtgt gtcttcgacg agataggcaa aatagccagc gcctattcca
    37441 atacctagag ctgcgaacat caaaagaaga acagtaataa aaacagtcaa tgattgaaaa
    37501 actctaaaaa taatcttagg aacaaaccat ttttcttttt ttcttctatt ctgttttttt
    37561 cgagtatttt tgcgtggcaa aagggtcacc tcaactaatg gttttatttc gctaattata
    37621 gcaaataata gaacaaaaaa acagacaagg ctgtttttgg caggaatttc ttttttaaaa
    37681 gagttaaaac gtgagaaaat gatctttatt ataaaagagt tcttaagctt ttctttagag
    37741 aaaatttcag ttactatgga gaacagggca aagaaaaatc aatcattttc tttgtatatc
    37801 atcttaccaa tatataggaa ttgttagtaa caattgcctt tcaaggagga atccatccat
    37861 gttattaggc tcacacgtca gcatgagcgg aaagaaaatg ctgttaggag cagcagaaga
    37921 agcagccagt tatggatctt cgacttttat gatctataca ggcgcccctc aaaacactag
    37981 aagaaaagcc atcgaagaga tgaatattga tgccggaaaa gcgtacatgg cagaaaaagg
    38041 tctaacaaat atcgtcgttc atgcccctta tatcattaat ttggggaata cgatcaaacc
    38101 agaaatgttt ccttttgccg tccaatttct gagagaagag attgttcgtg cggaagcttt
    38161 aggcgctact caaattacac ttcacccagg tgctcatgta ggggcaggaa cagaagccgg
    38221 aattgctaga attattgaag gcttgaatga agttttgaca aaagaacaga cggcacaaat
    38281 cgctttggag acaatggcag gtaaaggtac ggaaatcggt cgaacatttg aggaattagc
    38341 gcaaatcatc gatggagtaa aattgaatga aaaattatcc gttacttttg acacctgtca
    38401 tacgaatgat gccggttata atattaaaga agacttttca ggtgtaatgg aagagtttga
    38461 taagatcatc gggttagatc ggcttaaagt actccatatc aatgattcta aaaatccgca
    38521 aggttcgcat aaagaccggc acgccaatat tggttttgga acaatcggat tcgacacgct
    38581 gaataagatc gtccatgatc caatgtttga caatatttcg aaaatcttgg aaactcccta
    38641 tgtaggcaaa gataaaaaga aagcttacgc accatatgga aaagaaatcg ccatgttcaa
    38701 agcgcaaaca ttcgatccag aagtgtttcc tgagttatta gcagaagaag tgatactcta
    38761 agattttcta tctgacagca gcaaaaaagg accaggcaca ttgccttgtc cttttttgtt
    38821 taagaaacaa aggagtactt tttgcagtct ttttcatcat gcatcttctc ccccctcttt
    38881 ttaaatttag acaaacaagg tatactggta gaaaagtaaa aaaacgaaaa gtttcacaag
    38941 caagtggcaa aacgtgattg gaaggacgaa aagatgctga acactttaaa acccttgatc
    39001 aaccaactaa aaaagaaaca tacatacttt attcttggca tagccctatt atttacaatt
    39061 attcgtttgt atttatatag taaagcaatc tatggaacag acatgtcggc aacctatgat
    39121 gaccagctgc tgattcgcta tgctcaaaat attttggacg gtaaatggct aggggagtat
    39181 acgactacaa cactttccaa aggaatctcc tacagcttat ttttagtact tgcacataaa
    39241 ctgcatcttt cttatgcagt tttgttcggc atgttcagta tttttgccag tatattggtt
    39301 gcactcgcgt ttaaaccgat tgtgaagaac aagtatcttc ttttaagtat ctatttttat
    39361 tttttgtttt ctccgattag ttttacacat gaatattcca ctcgaacata tcgtaatgcc
    39421 ctcgtgattc cggctgttga gatcattatc gcttgtttat tagctattta ttaccgcaaa
    39481 tacggttcta gcagaaaatt gctgccatgg tttttagggc tttctgtcgc ttttcctttc
    39541 ttttggttca ttcgcgaaga ttctatctgg cttcttcctt ttactgtagt agctttgggt
    39601 atcagtttcg tccagatctt gctagggcaa gacttttctt tcaaagaagt aaagaagtta
    39661 aaaaaacgac tctttcttct ctcgaaacgg gaatggctga aactttcatt gtttttactt
    39721 cctatagttg gcttttccat cgtctatcaa tggatcgaat ataaaaatga gacaacatac
    39781 ggtattgcaa ccatcaatga ccgttccagt ggagaatttg gacgtttgat gaaacaactg
    39841 atccgaatag atgatgaaac gaacttgaat aaagaaaaca gtgagatatg ggtctcacat
    39901 gctgcactaa ataaagcatt agccgcatct cctacattcc atactgtttc tacccgtatt
    39961 gacgaattat atacgactca cgcgtggact caaggtggaa aagtaaaaga attacccgga
    40021 gatatcatct tttgggcatt gcgagatgtg gtaagcgaat ctggttatta ccaaaacaat
    40081 gcaaaagaaa ccaatgattt ttggaaaaaa gtcaaccaag aattagaaga agcctatcac
    40141 aagggaacaa tcaaaaagaa aaaagagttc tatctgatgg gatcaggaga tggaaagacg
    40201 atgagtgatc tgccaatcgt attcgatttc cttcaatcag gatacgctta tgcatggcga
    40261 tataaagatt tccatcaagg aggaaattat agtttcggaa cgcaagaaca agtcaaacag
    40321 gctcaagaat tattaaacct tccgctaatg gagaattgga tcgatagtaa tgaaccgaga
    40381 acacctaatt tccaattaac aaaatcagca aaagtcgcga atgtcatcat aaaaatttac
    40441 caagttctgg ctattcccgt gctgattgct tcaatagcag ggatattact tatgatacta
    40501 ggaaccgtat ttgcaaaagc tgatcgtgcc tattatagtt cctctttgat tgtggtcacc
    40561 ggattaatac tgacacaatt ggtttttctt ttcggtgtct catggttttg ttcttatgcg
    40621 ccagaaaaaa aggactattt tttaagtgtc tacactggtg caggcgtgcc attaacgcaa
    40681 ttcatcgtag taacaagcat gctagttttc agtaaattaa atctgaaaaa agctttatct
    40741 tctaaataaa aagacccttg gtagctagat ttttaaccta actatcaagg gtctttgtgt
    40801 ggaaaaatca gtttttattc gatttcttct accgtttcct gcaaaagctg ttcatatttt
    40861 ttgtttcctt tatataaatc accaatcgtc catgccaaca ggagaaggac aagaacaatg
    40921 attacataag cgatgtgatc agccaatgct agttgagcgg aagtggcttg ctcgccgaag
    40981 aaactttcga tctgtcctgg taatcctcgt aagttcaagt aagttagact aatcacagag
    41041 aaccagccaa gaagttttac gatgaatgaa tttttaaatc ggctacccat ctccgcttgg
    41101 ctgttggtca tcatcagtaa aggaatcatc gaaaacggca acgcaaaagc caagaacacc
    41161 tgggattcat tcattaagtt attcaaagcg gcatgttctt cgatcgttcc ttttgtactt
    41221 gtaaacaaaa cacaaatcaa tacaggaatc acagaaagca atcgtgtgac cagtcttctt
    41281 agccaaatcg ggatacgcat atggatgaat ccttccatga tgacttgacc ggtcaacgta
    41341 ccagtaatag tagagttctg gccagaagca agaagtgcta cagcaaataa agtggacaag
    41401 ataccagatt ttgctacagc aatcaaaata ccattgctca tagctgatgg atcagataaa
    41461 gcttcataca gaccaaaaaa ggaaggatct tggacagaac cggttttgaa gacagcgaca
    41521 cccatgatca atagcagtgc attgactaga aaagccattg acaactggat attagaatcc
    41581 caagtagaaa aacgtacagc ttgtgctaca tcttcttcgt tttggtgatc gatcttccga
    41641 gtttgtgaaa ctgctgaatg aagatataag ttatgcggca tgactgttgc accaataatc
    41701 cctaaagctc cagtcagcgg agtttcgccg ccgatgaccg gtgagtctga gaatgtatga
    41761 ctgttaggga taaagccagc aaataaactg tgccaatctg ggttagacaa gccaacttga
    41821 tagacaaaaa cgaataaaat gacgaaaatt aagcagacaa ccagtgcttc gatcttacga
    41881 aacccgactt ttgtcagtag taagagaacg aaaacatcta atacagtaat aaagacggca
    41941 atcaccaatg gaatatcaaa aagtaagtag agggcgattg ctgcaccaat gacttctgca
    42001 atatctgttg ccataatggc taattcagtc aagatccata aaatgacacc taatgtctta
    42061 cttgtgcgtg ctcggattgc ctgtgccaaa tccatttggc tcacgattcc taattttgct
    42121 gccatatact gtaaaagcat agcaatcaga ctagacatca aaataactga catcaataaa
    42181 tattggaaat tttgtcctcc ggtgatcgaa gtagaccagt tacccgggtc catataccca
    42241 actgctacta acgcaccagg tccagagtaa gcaagaagtg ttttaaaaaa acttttcccc
    42301 tttggtacat caactgttcc atttacttca gctaaagata aaccatttgt atgttcaata
    42361 agtcgatgct tatgaaattg tttattggat tgattattca agaaaaaacc acctttccta
    42421 tttatctacg attacattct acacctcaaa aagaaaaaat taaagaaaaa gattcggtac
    42481 gcctaatttt ttttcatggc gcgtcttgct agatgacgaa agaaattttg ttctcctcta
    42541 aaaaaaccac tattttttgc atgaaactaa agaatacgcc tttctttttt caataaactt
    42601 tagtaaaata agtcattgag agcaattcgg aaatagaaag gagagattta tatgttatca
    42661 acaggtattg tcgtacttat tgctattatt gctttgctaa tcggcgcagt aggtggcttt
    42721 ttcctagcgc gtaaatatat gaaagactat ttagaaaaaa atcctcccgt taatgaggac
    42781 atgttgcgat caatgatgat gtcaatgggg caaaaaccat ctgagaagaa aattcgccag
    42841 atgatgcagc aaatgaagaa ccaagggaaa aaataggttc tgacccaacg actttttacg
    42901 ggctgatttt ttcagtccgt tttttatttc gtaatttgtt agactattca gattattcag
    42961 caaaaaagac aagcacagac aatcctaggc tcttgataaa gacaaaggag gagtaaaatg
    43021 tcgattttta gaaaattagg ctggtttttt cgtcaggaaa agaaacatta tttaattggg
    43081 gttttctcgc tattcgcagt ggccttggta cagttagttc ctccaaaagt gattgggatc
    43141 atcattgatg agatcgccga taaaaattta tcaataaaga tcattttcgg gtggatcttc
    43201 ctattgatta tcgctgcttt tttacaatat ctttttcgtt atatctggcg gacgaatatt
    43261 tggggaagtg cagctcgatt ggagaaagaa cttcggcagc agttattcaa acattttaca
    43321 gaaatggaca atctctttta ccaaaaatat cggactgggg atttgatggc tcacgcaacg
    43381 aatgatttga atgcgatcca gaatgtagca ggagctggta tcttgacctt tgcagattca
    43441 gtgattacgg gcggaacaac gatcattgcg atgattttgt ttattgattg gcgcttaaca
    43501 ctgattgcgc tgattcctct gcctttgctg gccgtcactt cacgagtgct ggggtcaaaa
    43561 ctccatgatg cttttcgtga ttcgcaagaa gctttttcta gtatcaatga taagacacaa
    43621 gaaagtatca ctgggatcaa agtcattaaa acatttggac aagaaaaaga agatctagcg
    43681 gattttgaag aaaagattga agatgcaatt attaaaaaca aacgagtcaa ttttttagac
    43741 tccttatttg atccattcat taccttgatt atcggtctgt cttatgttgc aacaattatt
    43801 ttaggtggaa agtatgtctt ggaaggcacg atctcgatcg ggcagatggt ctcatttatt
    43861 agttatatcg gtatgcttgt ttggccgatg tttgcgattg gtcgattgtt caacgtattg
    43921 gaaagaggaa atgcttctta tgatcgcgtc aatgaacttt tgcatgaaaa gacgcatatc
    43981 gtggaacaac tgggtgcagt gcagaccccg gcaaaaggcg agctgaatgt agctatttcc
    44041 tcttttaatt atccgaaaga agaatcacca gcattagaac aaatcaagtt tgcgatccaa
    44101 gaaggagaaa cattaggtat tgttgggaaa actggtgcgg gaaaaacgac gatcatcaaa
    44161 ttactgatgc gtgaatacga tgattatcaa gggaaaatcc aatttggcgg acgttcgatc
    44221 aaagaatatt cattgaatgc tttattagga tcaatcggct atgtgcctca ggatcacttc
    44281 ttgttttcga tgaccattcg agataatatc cgtttttcta atccaaaact ttcagaagaa
    44341 gaagtagagc atgcggcttc tttagcattt atcaacaatg aaatcaagga attaccaaaa
    44401 ggttatgata ccttagttgg agaacgtgga gtctctttat ctggcggaca gaaacaaagg
    44461 atttcgattg ctcgagcatt gatcaaaaat cctgaattat taatattaga tgatgcactc
    44521 tctgcagtag atgccaaaac agaagaagct atcttgcata atttaaaaga aataagaaaa
    44581 gagaaaacaa ctatcattgc agctcaccgt ttaagtagcg tgatgcatgc aaaagaaatc
    44641 attgttgtcg atcaagggaa aatcattgaa cgaggaaccc atcatgagct gcttgcacta
    44701 ggcggctggt atgaacaaat gtgggagaaa cagcaattag aagcgaagat agaaggaggc
    44761 gaggcctgat ggatgaaaat tatcaatcgg aatggacaaa atcgattcca cttaaagaac
    44821 agaaaaagat catcaaacga ctgatgaagt tcgccaaacc ttttagaaga acgttcatcg
    44881 ttgctatctt atttgcgttt gctttgtctg tgatcaatgt cctattgcca aggatcatcc
    44941 aaacttttat ggatgatcat ctggctaaac agtcggctac gacacaagtt attttgtttt
    45001 ttgctggtat gtacttattt ggagtcatag taaaaagtat catttggttt ttccaatggt
    45061 atttgtattc catggcctca ttgaagacct atcagtatat tagggtaaaa ttatttgaaa
    45121 agctgcatac actaggtatg cgttattttg atcagacacc ggcaggatca accgtttctc
    45181 gagtgacgaa tgacacagaa acgctatttg aattttggta cgtctttttg atggtattga
    45241 ctgggatctt tgcagtcgtt tcttcattcc ttgccatgtt tcaaatcaat ggagaaattg
    45301 ccttgtggac tttggtgttt ttgccgattt taggaatcgt catctggtat taccagaaat
    45361 tcagttctcg tatttaccga aatatgcggg aaaaattaag tcagctgaac acgaaattga
    45421 atgaatcgat ttccggcatg cgtattatcc agcagtttcg ccaagaagct cgtttagcta
    45481 aagaatttga acaagtgaac aatgagtatt tagacacgcg ttatgcgatg atcaaaacga
    45541 attcgattct gttaagtccg atcatcaatt ttctatatgc attggcgatt gcgttggtgt
    45601 tgactttgtt tgggatcgat gcgttgcatt ctcccgtaga agttggactg atctatgcat
    45661 ttacgaccta tgtccaggga ttttttaatc caatgtctca aatgatggac tttttgagca
    45721 tcttcacaga tgggatggtt gctggtagtc gtatcttgaa gattatggat acggaagaat
    45781 atgcaccaca acaaaaccct ggagcagatc aaatgattac ttcaggtaag attgagtttc
    45841 gcaatgtaag cttttcttat gatggagagc acaatgtatt aaacaatatc tcttttgttg
    45901 ctaatccggg agagaccgtt gcattagtgg gacacaccgg aagcggaaaa agctcgatca
    45961 tcaacgtatt gatgcggttt tacgaatttt atgaaggtca gatattgatt gatgatcatg
    46021 acattcgaga atatccaatg gaagagttac gtaagaaaat ggggctggtc ttgcaagatg
    46081 ctttcttgtt ttatggggat atcgcaggaa atattcggat gatgaatcca gctatcacag
    46141 acgaacagat acgccatgcg gctgagtttg ttcaagcaaa caaattcatc gatgaattac
    46201 caaaaggata tcactcaaaa gtgatcgaac atggtgccag ctattctagt ggacaacgac
    46261 agctgatcac ttttgcgcga acaatcgtga ctgatcctaa aattctagta ttggatgaag
    46321 caacagcaaa tatcgatact gaaacagaag gattgatcca agaaggattg gcaaaaatgc
    46381 gtcaaggacg gacaacgatt gcgattgccc atcggctgtc aacgattcga gatgcagaat
    46441 tgattttagt tttagacaaa ggtcatatag tagaacgcgg gaatcatgaa acacttctag
    46501 cgcaaaatgg tttgtatgca gatatgtaca aactgcaaag cagtggtata taaaagatgt
    46561 tgtgacagta gaattttgac ctaagcacta gagtgaaaat aaaacatagc ttctcatatt
    46621 tttcatctgt gagagttagt gtcgtagtca ccagatttaa aaaaagattc gacagctagt
    46681 cagaagtgcc taatagccac taagaaagcg ttgacaaaag catttgcttt cgataatata
    46741 aagaaaacga tacaacttgg atagtgattg cctgatgcaa gctaaacctg atgagtctcc
    46801 catggtttca tggacggctt tttgggtttt tctttttgtt ttggatacag ccctatacat
    46861 catggaaagg agcaaaacat gctgattgag aaagtactga ataacaacgt cgtaataacc
    46921 agggatgaaa gaaatcagga aatgatcgtg atgggaaaag gtttggcatt caaaaagaaa
    46981 gtgggtgacc cgatttttga ctcatgcatc gacaaaaaat ttcagttgac aaatgacggg
    47041 ctttcacaac agttccaaga attggcacaa gcgattcctc ttgagtactt agaaatttct
    47101 tgtgaaatca ttgaatatac aaaagaggct ctacaagtcc agttgaatga ttctgtgtat
    47161 attgcattga cggatcattt gtatacggct atcgaacgtc acaaaatggg aatatttgta
    47221 ccaaatgtat tgctgtatga tatcaaacaa ctatttccta aagagtatgc catcgggaaa
    47281 aaaacagtga agaaaatctc ggataaatac cacatcaagt tatcagaaga tgaagccgga
    47341 tttatcgcat tgcatttagt caatgcacaa ggcattcaaa gccagcaaga caatacctac
    47401 ctgtttacta taacaataca ggatattcta aatatcgtcc gctattacta taagattaca
    47461 tttgatgaag attcagtcca tttttttcga ttcgtcacac acttacgttt ttttctgaca
    47521 cgcgtcctag atggagaaaa atcagaagtg ggagaagttt ctgaggaatt gtttcaggtt
    47581 attcaaaaaa aatataagga tacgtttggt tgcgttgaga aaatagcaga ctttttagcc
    47641 gagacgttca actaccagat gtccacggac gaaaaaatgt atttaacgat ccatactgcg
    47701 cgtttagtgc atgagaatcg ttgtaaataa aaaaaggagg ataaattaac aagaacgtat
    47761 gaaataaggg tagtgacatt cagttggcta aaccttccac taataaattg gagggaatag
    47821 aaatgggaaa ataccaagaa ttagcgagaa aaatcgtaga aaatgtcggc gggaaggaaa
    47881 atatcaatgg tttgacacat tgtatcacaa ggcttcgttt caaattaaaa aacgaagaaa
    47941 aagcaaatga tgagatcttg aaaaatatgg acggtattgt aacggtaatg cgagcgggag
    48001 ggcagtatca agttgtcatt gggaatcatg tgccagtcgt gtttgaagag gttataaaag
    48061 caggaaacct tacttttgat gaggctgttt caacagaaaa aatgagaccg tttgatatgc
    48121 ttattgatgg aatatcgggc tgtttccagc cattccttgc tatcctagct gctggcggga
    48181 tgattcgtgg actgacagca ttccttgtct tcttaggcgc gtttgaccgc ggttctggca
    48241 catttgttat gtttgataat atcggtgatt ctgtattcca atttatgcct gttattatcg
    48301 gtttaacagc tgcccgtaaa tttaaagtaa atgaattcgt agggatgttg cttggcgcag
    48361 cattaatgaa tcctagcttg tcgctggaag ctttgagtgg tgcagcagaa gcaccactaa
    48421 cgaccatatt ttctggcact atttttgaag cacctattta tcaaacagta ttcggcattc
    48481 cctggattgc gcgtaactac gcttcttctg tcattcccat tatctttatt gtgttgttag
    48541 ctagccaaat tcagaaacca attaaaaagt tagtacctga gatgatcgcg aatttcttcg
    48601 ttccattctt caccgttctt attacaatgc ctttaggttt tttactcgtt ggaccagtat
    48661 tcacattcgc aactgatatt ttaatggctg gatttgaaac acttttagca ctttcgccag
    48721 ttatttatgg agcaatcgta ggcttcttct ggcaaattct ggtgatgttt ggtctccatt
    48781 gggcaatcgt accaatggga ttgatgcaat tttctgtgaa tggttggcaa aatattatga
    48841 cacctgttgc agtagtgtct tttggacaaa ctgcagcact taccgcactc tactttaagc
    48901 ttagaaatcc aaaagacaaa gcaattgcaa taccagccat tgtttctggt attgtgggga
    48961 ttacagagcc agctatttat gggtttacat taccacgtaa aaaaatattt atttttacct
    49021 gtgtcggtgg tgcgttaggg ggcgcgtata gtgggttaat gaatttaact tcttggaatc
    49081 aaggtggact aggcatcttt acaattccca actatattag accagatggt gatttaacag
    49141 atgtgattaa tgtattgatt gggatcgcca ttgcgatggt ggtatccttt acgctgactt
    49201 ttttcttttg gaaggatgaa gcaggtgaaa cagatgatat acagaaaaaa tcaggtaaag
    49261 aaattgtaaa aacaccgata caaggacaaa tcgctccact aaatgcagca aaggatgcag
    49321 cttttgcaca aggaacacta ggtcgaggaa tcttgatcta ccctgaaaaa ggagaagtac
    49381 gtgccccttt tgacggaaca gtcatgaccc tgttcccgac gaaacaggca attggaatgg
    49441 tttctgaaac agggctggaa ttgctgattc atgtcggatt ggatactgtg cagttggaag
    49501 ggaaatattt tgaaagctta gtgcagcaag gataaagagt gaaacaaggc gatctgttgc
    49561 tacgcttcga caaaaagaaa atcgaaaagg aaggatacag tttagaaaca cctgtgatcg
    49621 tcaccaatta cacggattat ttggatattt tggaaaacca aggggagacg gtcgggccag
    49681 acgatgcact tatcaccgca ctgacctgaa cggttaggtg aagaatggac taggcttaac
    49741 tattcttttt attccacttc tttattttca aaattgaaag gctctttcat gatggctgag
    49801 ctgatagggc gtttatcgaa tttttgaccg acagaaatta gatggactaa attctgttga
    49861 taattttctg caaaaacaca actatataac acgtctagaa gataacaaat tgatgtattg
    49921 atcgtaaaat taccaatttt tgaatacagt cgctcgcgtg tcgtaagtcg caaagcggct
    49981 gtactcattg cagatagcgt tgaatcaccg atactggtca aagctaaaat tggaacatga
    50041 ttttgtttca atatttctgc ggtacgaagg atcacattgt tttcacccgt ataagaaatc
    50101 agaatcccgc acatatcact cgtgcaattg tacgcttcat agaatgattc accaaaagtg
    50161 gtgacaatcg tgacatccat tttgatgcgc ttcattttca gcatgaaatc ttgagaaatc
    50221 aaagtattcg agttactggc gaaaatcacg attttttttg cttgaagcat tagttgtttg
    50281 gctttttgca gttggtcatg atgaatgaga gaaagtgtat catgaatcgt catctgttct
    50341 aaagaagcca ttttatttgc gatcgtcata ataccgtctg tggtggaaaa aggaagattc
    50401 gcatctacgt cttgaaaatt cccttcaaga taggctgttt cagctaaaaa agcattacga
    50461 aaactgaccc agccatcaaa acccattttt tttgctacac ggatgagtgt agaggggtgg
    50521 acataacatc gctcagcaat cgcttggatg gtcatttcgc caagtgctgg agaatcgctt
    50581 aagagaaact ggatcacttc attttctgaa ggagaaaagg agatttcttt gattttttca
    50641 cgtaataaca tgtagatacc ttcttcttat ttttttacgt aaattataac ttttttgaaa
    50701 at
//
LOCUS       DACGDM010000014        45012 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.014, whole genome shotgun sequence.
ACCESSION   DACGDM010000014 DACGDM010000000
VERSION     DACGDM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.014"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            211..603
                     /locus_tag="IXR05_000864"
     CDS             211..603
                     /locus_tag="IXR05_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4259402.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            631..1971
                     /gene="glnA"
                     /locus_tag="IXR05_000865"
     CDS             631..1971
                     /gene="glnA"
                     /locus_tag="IXR05_000865"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAQ4259403.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3164..4774
                     /locus_tag="IXR05_000866"
     CDS             3164..4774
                     /locus_tag="IXR05_000866"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAQ4259404.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5066..5935
                     /locus_tag="IXR05_000867"
     CDS             5066..5935
                     /locus_tag="IXR05_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAQ4259405.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6100..7371
                     /locus_tag="IXR05_000868"
     CDS             6100..7371
                     /locus_tag="IXR05_000868"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4259406.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7368..8663
                     /locus_tag="IXR05_000869"
     CDS             7368..8663
                     /locus_tag="IXR05_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAQ4259407.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8762..9025
                     /locus_tag="IXR05_000870"
     CDS             8762..9025
                     /locus_tag="IXR05_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAQ4259408.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9470..9919
                     /locus_tag="IXR05_000871"
     CDS             9470..9919
                     /locus_tag="IXR05_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4259409.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9976..11394
                     /locus_tag="IXR05_000872"
     CDS             9976..11394
                     /locus_tag="IXR05_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4259410.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11394..12254
                     /locus_tag="IXR05_000873"
     CDS             11394..12254
                     /locus_tag="IXR05_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAQ4259411.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12428..13201
                     /locus_tag="IXR05_000874"
     CDS             12428..13201
                     /locus_tag="IXR05_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4259412.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13348..13713
                     /locus_tag="IXR05_000875"
     CDS             13348..13713
                     /locus_tag="IXR05_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAQ4259413.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13861..15069)
                     /locus_tag="IXR05_000876"
     CDS             complement(13861..15069)
                     /locus_tag="IXR05_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4259414.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15088..15366)
                     /locus_tag="IXR05_000877"
     CDS             complement(15088..15366)
                     /locus_tag="IXR05_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259415.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15559..16215
                     /locus_tag="IXR05_000878"
     CDS             15559..16215
                     /locus_tag="IXR05_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4259416.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16657..17454)
                     /locus_tag="IXR05_000879"
     CDS             complement(16657..17454)
                     /locus_tag="IXR05_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAQ4259417.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17451..18635)
                     /locus_tag="IXR05_000880"
     CDS             complement(17451..18635)
                     /locus_tag="IXR05_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4259418.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18660..19907)
                     /locus_tag="IXR05_000881"
     CDS             complement(18660..19907)
                     /locus_tag="IXR05_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAQ4259419.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20122..21867
                     /gene="dnaX"
                     /locus_tag="IXR05_000882"
     CDS             20122..21867
                     /gene="dnaX"
                     /locus_tag="IXR05_000882"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAQ4259420.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21887..22201
                     /locus_tag="IXR05_000883"
     CDS             21887..22201
                     /locus_tag="IXR05_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAQ4259421.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22226..22822
                     /gene="recR"
                     /locus_tag="IXR05_000884"
     CDS             22226..22822
                     /gene="recR"
                     /locus_tag="IXR05_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAQ4259422.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22886..23530
                     /locus_tag="IXR05_000885"
     CDS             22886..23530
                     /locus_tag="IXR05_000885"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAQ4259423.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23545..23874
                     /locus_tag="IXR05_000886"
     CDS             23545..23874
                     /locus_tag="IXR05_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259424.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23888..24826
                     /gene="holB"
                     /locus_tag="IXR05_000887"
     CDS             23888..24826
                     /gene="holB"
                     /locus_tag="IXR05_000887"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAQ4259425.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24862..25686
                     /locus_tag="IXR05_000888"
     CDS             24862..25686
                     /locus_tag="IXR05_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAQ4259426.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25679..26026
                     /locus_tag="IXR05_000889"
     CDS             25679..26026
                     /locus_tag="IXR05_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAQ4259427.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26095..26967
                     /gene="rsmI"
                     /locus_tag="IXR05_000890"
     CDS             26095..26967
                     /gene="rsmI"
                     /locus_tag="IXR05_000890"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAQ4259428.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27076..28197
                     /gene="dinB"
                     /locus_tag="IXR05_000891"
     CDS             27076..28197
                     /gene="dinB"
                     /locus_tag="IXR05_000891"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAQ4259429.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="IXR05_000892"
     CDS             complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="IXR05_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAQ4259430.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYAFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="IXR05_000893"
     CDS             complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="IXR05_000893"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAQ4259431.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKNQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGSFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31683..32450
                     /locus_tag="IXR05_000894"
     CDS             31683..32450
                     /locus_tag="IXR05_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259432.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32440..34482
                     /locus_tag="IXR05_000895"
     CDS             32440..34482
                     /locus_tag="IXR05_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259433.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34763..34912
                     /locus_tag="IXR05_000896"
     CDS             34763..34912
                     /locus_tag="IXR05_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAQ4259434.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34923..36437
                     /gene="dltA"
                     /locus_tag="IXR05_000897"
     CDS             34923..36437
                     /gene="dltA"
                     /locus_tag="IXR05_000897"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAQ4259435.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36434..37639
                     /gene="dltB"
                     /locus_tag="IXR05_000898"
     CDS             36434..37639
                     /gene="dltB"
                     /locus_tag="IXR05_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAQ4259436.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37684..37917
                     /gene="dltC"
                     /locus_tag="IXR05_000899"
     CDS             37684..37917
                     /gene="dltC"
                     /locus_tag="IXR05_000899"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAQ4259437.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37920..39188
                     /gene="dltD"
                     /locus_tag="IXR05_000900"
     CDS             37920..39188
                     /gene="dltD"
                     /locus_tag="IXR05_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAQ4259438.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39329..40411
                     /locus_tag="IXR05_000901"
     CDS             39329..40411
                     /locus_tag="IXR05_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAQ4259439.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40411..41214
                     /locus_tag="IXR05_000902"
     CDS             40411..41214
                     /locus_tag="IXR05_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4259440.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41284..42024
                     /locus_tag="IXR05_000903"
     CDS             41284..42024
                     /locus_tag="IXR05_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4259441.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42035..43039
                     /locus_tag="IXR05_000904"
     CDS             42035..43039
                     /locus_tag="IXR05_000904"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAQ4259442.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43084..44928)
                     /locus_tag="IXR05_000905"
     CDS             complement(43084..44928)
                     /locus_tag="IXR05_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259443.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14482 a         7842 c         9358 g        13330 t
ORIGIN      
        1 ataaaaacac taataaagga tagtacagta taataaaaaa taaaaggtat ctggtacgaa
       61 aatcaactag ataccttttt tgtgttctta tttttttgtt attttataaa aaatagagat
      121 ctcatgttag aaaacctaac atatgcagtt gacaatattt tttttaattg gtacacttta
      181 gccaacttat aaaacgaaag gggacgtctg atgggagaaa aggaattgcg ccgatctatg
      241 tccgtatttc caattggtac agttatgaag ctgactgatt tgtctgctcg gcaaattcgc
      301 tattatgaag aacaagattt agttcatccg gaacgaagcg aaggaaaccg acgtatgtat
      361 tcgctgaatg atattgatat gttgcttgag attaaagact atctttcaga gggattgaat
      421 atggctggga tcaaacgtgt atacgaaatg gcacaggcga aaaaacaaga agcaaaaaac
      481 aagaagccgt tgacagatca tgacgttcga caaatttttc gtgatgagat tttggcgcaa
      541 ggtgggttaa gcaaaacagg tcattatcag tcgcaaggat tgcaaagaca attctttgac
      601 tgaataaatt aaaaaaggaa gagggatacc atggtaaaga aacagataac aggtgaagaa
      661 atcaaacgaa tcattgagga agaaaacgta cgatttttac gattgatgtt cacagacatc
      721 ttaggtacga tcaaaaatgt agaagttcca gtgagccaga tcgacaaagt attagaaaat
      781 aaaatgatgt ttgacggttc ttcgattgaa ggatttgttc gaattgaaga aagcgatatg
      841 tatttgtatc cagatctctc cacttggatg atcttcccgt gggaaagtgc tcatggaaaa
      901 gttgctcgtt taatttgtga tatctataat ccggatggga caccatttgc cggcgatcct
      961 cgcgggaatt tgaaacgagc attgaaagat atgcgcgacc ttggttttac ctctttcaat
     1021 ttaggacctg aaccagaatt cttcttattt aaattagacg aagacggtgg gatcacaacg
     1081 accttgaatg ataaaggtgg ttattttgat tttgcaccaa cagatttagg tgaaaattgc
     1141 cgccgtgaca tcgtgttgga attagaaagt ctaggctttg aagtggaagc ttcacatcat
     1201 gaagtagcgc caggacagca tgaaattgac tttaaatatg cagatgtggt agatgcttgt
     1261 gataatatcc aaaccttcaa gctcgttgtc aaaacgattg cacgcaagca tggacttcac
     1321 gcgactttca tgccgaaacc gttatttggg atcaatggtt ctggtatgca ttgcaatatg
     1381 tctttgttca atgatgaagg aaatgttttc tatgataaag acggtgaatt ggaactaagt
     1441 gaaacagctt atcatttctt aggtggtttg ctgaaacatg ctcgtgccta cacagccgtt
     1501 tgcaatccaa cagtcaattc ttataaacgt ctcgttccag gttatgaagc gcctgtttat
     1561 gtcgcatgga gtggccgtaa tcgttcgcca ttagtacgtg taccagaatc tcgcggttta
     1621 tccacacgtt tggaattgcg gtcagttgat ccatctgcaa acccatactt ggcaatggca
     1681 gtattgttgc aagcaggact agacggtatc cgtaatcaga tcacaccgcc agcagctgtt
     1741 gaccgtaaca tttatgtaat ggatgaggaa gaaagagaag ctgcacatat ccaggactta
     1801 ccttcaacta tccataatgc tatcaaagaa ttgcgtaagg ataatgtaat gattgacgca
     1861 ttaggacaac atatcttctc aaattttgtt gaagcaaaac gtctcgaatg ggcggcattc
     1921 agacaaactg tttccgagtg ggaaagagaa caatatctag aactttatta aaacaggaat
     1981 accgtgaatt agaggctgtg aaatcagcgt tttgacctga gtattagaga aactaacgga
     2041 aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag ctgattgaac
     2101 accgtttagt ggagaggttg tgaaaaagct gccctgcaac aagtaataag aatagccaag
     2161 caaaaacagc ttttcttgtt tttgaattgg ctgaacttat taccgcagat gcaagctttt
     2221 gaacaccgtt taccaagagg ttttgaaaaa gacgtttagt ttcgagtatt aagaaaaatt
     2281 ttgtgaaaat ggctttctac atttttgcat aaatttggct taataccgag aaactggctt
     2341 ttgaataccg tttatccaga ggttgtgagc ctaccattta actccgaatc acaagaaata
     2401 atttcaaaaa cagcttctca tgtttgatgg atattgtgac ttgtgaccga ggagttggca
     2461 ggagaacacc gtttatttag aaataaggag gcacgacttt tgtcgcatct ccttattttt
     2521 tacttatgtg attcgttacc ttcaatgaat ccctacaagg cacttttgtt gaaaaaaagg
     2581 tcatctttga aaaaattagt ggaattgttt tgtttttgat attatttaat agaaaagata
     2641 tgccaaaaat ccgagaactg tggactacgt tttttacgta aaggaggtaa ataagggtga
     2701 aagaaaaaga ttgtttctac gataagctat ataaactgtt gctgcaagta ggaaaaagta
     2761 gttctttgtt aggtgggata ttatctatca taatgtttgt tttatttttt tatctattat
     2821 ttcacttaaa atttttcagt aacgattttc tgatttgctt aggtttaacg ttagctatgt
     2881 ttatatcaag cttattatgt gggttaaatt ttttttgcac tcataaagga cttaagaaat
     2941 aatttctcaa aggatatcga aaaagaaaaa attgtaagcg gatagtattc atttgagtac
     3001 ttgactttcc cttagtcagc ttgtattata caccttgggc acccttttag agggtcagaa
     3061 gtttacagaa atttcggctc cctattctta ttgaagaata gggagctttg tttattgtct
     3121 gagacttttc ctgcacataa attaaaaagg agtttttgaa cttatgacaa aatatatttt
     3181 tgtgaccggc ggtgtcgttt catcaatcgg aaaagggatt gttgcagctt ctttaggacg
     3241 cttattgaaa aaccgcggct taaaagtaac tatccaaaaa tttgatccat acatcaacgt
     3301 ggatccgggg acgatgagcc catatcagca cggagaagta ttcgtaacag atgatggtgc
     3361 tgaaacagat ttggatctgg gccactacga acgttttatt gacatcaatt tgaacaaata
     3421 ctccaacgtg acgacaggaa aaatctattc tgaagttttg cgtaaagaac gtaagggcga
     3481 atacttggga gcaactgttc aagttattcc tcatattaca aatgagatca aagaaaaaat
     3541 catgcgagca gctaaaatga ctgattcaga tgtgatcatt acagaagtag ggggaacagt
     3601 aggggatata gaatctttgc cattccttga agcacttcgt caaatgaaag cagatgtcgg
     3661 tacagataat gttatgtata tccatacaac attgattcct tacttgaaag ctgctggaga
     3721 aatgaaaact aaaccaacgc agcacagtgt aaaagagcta cgtggtttag gtatccaacc
     3781 gaatattttg gtggtacgta cagagcaacc tgtttctcaa agcgtgaaaa acaaattggc
     3841 acaattttgt gatgtcgaac cagaagcagt tatcgagtcg ccagatgtag atacacttta
     3901 ctccatccca ttagttttac aagcacaagg aatggatcaa attgtttgcg accatttaaa
     3961 actagataca ccagaagcag acatgacaga atggaaagaa ttagaagaac gtgtcttgaa
     4021 cttgaagaaa aaagtacgga ttgcgcttgt cggtaaatat gtcgagttac cagatgcata
     4081 tatctcagta gttgaagcat tgaaacattc tggtttcgcc tataattcag acatcgagat
     4141 cgattggatc aaagcacaag aattaacgag agaaaatgta gaagaacgtt tgaaagacgc
     4201 agatggaatc ttggttcctg gtggatttgg tgatcgcgga gtagaaggga aaatcgaagc
     4261 gattcgttat gctcgcgaaa atgacgttcc gtttttaggt atttgtcttg gtatgcagat
     4321 ggcttgtgtc gaatttgcac gtaacgtcgt tggattagaa gatgcgtcat cagctgaaac
     4381 gaatccagat acagcaaaca atattattga tttaatggct gatcaggaaa acatcgagaa
     4441 tttgggtgga actttacgcc ttggattata cccatgtaaa atcaaaaaag gaacgaagac
     4501 ggctgaagca tatgatggag ccgatgttgt gcaagaacgt caccgtcacc gctatgagtt
     4561 caataacaaa tatcgtcaat tgtttgaaga acaagggcta gtcttttcag gtgtctcacc
     4621 agataaccgt ttagtagaaa tcgtagagct gccagagaaa aaattctttg tgggatgcca
     4681 attccaccca gaattgattt ctcgtccaaa tcgcccgcaa aaattaatca aagcatttgt
     4741 cggagcatca ttagcagatc acgaaacaaa ataatttttg aacttgatag aaagagaaaa
     4801 gtagcaagag aaggggataa gcaattttct tgtcactttt ctctttttct gatttgttat
     4861 tatttgtagg aaaaaagata gaaagcaaaa gacttttttc gattaaagcg ctattggata
     4921 ttttattttt tgcaaaaaac ttcttgaaaa ttttcatttt cattgatttt agtagaaaac
     4981 taccgaaatg tttggtaaaa tagggtcgtt ggttaagaat tgtcttaaca aatttagttt
     5041 tacaaaactt aggaggaatt ttattatgcc agtagtatca ggagctgaat ttttaaaagc
     5101 tgctcgtaaa ggcggttacg ctgtcggcgg attcaacaca aacaacttgg aatggactca
     5161 agcaatcctt gaagcggctg aagcaaaaca agcaccagta cttatccaaa catcaatggg
     5221 tgcagctaaa tacatgggtg gttacaaaat ctgtaaagat ttaatcactg atttagttga
     5281 agcaatgaac atcactgttc cagttgctat ccacttagac catggtgatt acgaagctgc
     5341 tttggaatgt atcgaattag gctatacttc agtaatgttc gatggttcac atctaccatt
     5401 tgaagaaaac ttgaaattag ctaaagacgt tgttgaaaaa gcacatgcaa aaggtatctc
     5461 agttgaatgt gaagttggtt caatcggcgg agaagaagac ggaatcatcg gtaacggcga
     5521 attagctgat attgaagaat gcaaacaaat ggttgctaca ggtatcgact acttagcttg
     5581 cggtatcggt aacatccatg gtcaatatcc agaaaactgg aaaggattag cttttgacca
     5641 cttacaagca attgctgatg ctgtaggtcc agacatgcct ttagtattac atggcggatc
     5701 aggtattcct caagatcaaa tcgaaaaagc tatctcaatg ggtatctcaa aagtaaatgt
     5761 taacactgaa ttccaattat catttgctgc agctactcgt aaatatatcg aagctggtaa
     5821 agataaagaa ggtaaaggat tcgaccctcg taaattatta gctccaggta aagcagcaat
     5881 cgttgaagat gctaaatctc atatcgactg gttcggttca gctaacaaag cgtaagcatc
     5941 cacataacag atacgatata taggaatgga gaacgacttt tgaagtcgct ctccattctt
     6001 ttttacttaa aacggcagac catgctcgtt tctttttttt atctatgata aaatacaagc
     6061 atatccatga aaaaagatta ataaacaagg tggaaacaga tgaaaaaaat cgtaatcaaa
     6121 ggaaaccgac ctttagctgg tgaagtaacg atcagcggtg caaaaaatag tgcagtcgca
     6181 ttgattccag ctgcaatctt agctgattcc ccagtgatct tggaaggtgt gccggacata
     6241 caagatgttc attcattaat tgaaatttta gagatcatgg gcgcaactgt ccatttttcc
     6301 aacaacatac tagaaatcga tcctcgagaa gtcgtatcga ttccgatgcc gcacggaaaa
     6361 atcaatagtt tgcgtgcttc ttattatttt atgggaacac tgcttggtaa atttggcgaa
     6421 gcggtagtag gcctgccagg tggctgttat ttaggcccta gaccgattga cctacacgtc
     6481 aaaggatttg aagctctagg tgctgaagtg acaaatgaac atggtgccat gtatttacgg
     6541 acagaaaata aaggattgcg tggcaatcgg attttcatgg acgtggtttc agtcggagca
     6601 acgatcaatg tgatgttagc tgctgtaaaa gcaaaaggac agacagtaat tgaaaacgct
     6661 gcacgagaac cggaaatcat agatgtggca actttactga ataatatggg ggcaaaagtt
     6721 cgaggagcgg gtacagatgt gatccgtatc gaaggagtcg aaacattaca tggctgtcgg
     6781 catttcatga ttcctgaccg catcgaagca ggaacctatc tagcattagc agctgcagta
     6841 ggaaatggta tcaaagtgaa aaatgtgatc tttgaacatt tggaaagctt tatagcaaaa
     6901 ttgcaggaaa ttggtgtcca tatgaaaatc agcgaagatg aaatcgaagt ttacccctcg
     6961 aaagaattaa aacccgcaaa catcatgacc tatccttatc caggatttgc cacagatctg
     7021 cagcagccac ttactgcgtt actattgatg actacaggca cttcagaaat catcgatacg
     7081 atctatgcga aacgtgtgaa ccatgtgccg gaactagcac gaatgggcgc tgatattacc
     7141 gtggaaggaa atatgatcat cgtgaatggt ccaaataaac ttcacggcac agaagtcgtg
     7201 gcttctgatc ttcgggcagg tgcttgttta gtgattgctg gactattggc agaagggaca
     7261 acgacgattt acaatgtaga ttatatctta cgcggttatg atcatattat cgagaaacta
     7321 acagccttag gggcatcaat tgaaatgata gaggaagtgg gagctgaatg agcgattatt
     7381 tgacaatggc agaactagag aacaaaacgt taaaagaagt ttatagttat gccaaagaat
     7441 ttaaaattcc ttattacagt aagatgaata aaaaggaatt atctctagct gtgattcgtg
     7501 cacaagcaga gaaacaagga ttttattata tggaaggaat attggatatc gttggtcaag
     7561 atggttacgg ttttttacgg ccaatcaatt atggaccaag tgcagaagat atctatattt
     7621 ctgcctcaca aatcagacga ttcagtttga gaaatgggga caaagtggca ggaaaagccc
     7681 gtccacctaa agaatcggaa cgttattatg gtttgatgca cgtggaaagc gttaatggaa
     7741 aagatccgga agaagcaaaa gaacgtccgc attttccagc cttaacacct ctttatccgc
     7801 aaagacagct tcaactggaa acaacaccgc aaagactatc tacccgaatg atcgatatct
     7861 tttctccaat cggttttggt cagcgtggat tgatcgtcgc accgccaaaa gcagggaaaa
     7921 cttctgtatt aaaagaaatc gcaaatggta tcaccgaaaa ctatccggaa gtagaattaa
     7981 tcgttctact gattgatgaa cgaccggaag aagtaacgga tctagaacga agcgtgaaag
     8041 gcgacgtggt atcttctaca tttgatctgc agccgcaaaa ccatactcga gtttctgaat
     8101 tagtattgga acgcgcaatg cgtttagtcg aagataaacg agatgtcgtt atcttgatgg
     8161 atagtattac tagacttgct cgggcctata acttagtcgt tccaccaagc ggacgtacat
     8221 tgagtggcgg gattgaccca gccgcattgt ataaacctaa gaaatttttc ggggcagcaa
     8281 gaaacatcga agaaggtggc agtttgacga ttttagcgac cgctttagtc gatacaggaa
     8341 gccgtatgga tgacgtgatc tatgaagaat tcaaaggaac tggaaatcta gaattacaac
     8401 tttcacgtga attatctgaa cgtcggatct tcccagccat cgatatcaaa aaatcaggta
     8461 cccgaaaaga agaattattg atgccaagtg aagaattaga agaaatttgg aaacttcgaa
     8521 aaaatatgac tggagattca ttagaatata cggaacaact gatccgcttt ttgcgtaaaa
     8581 caaaaaacaa tcagcaattt ttcaaagaat ttcaagatgt ctcctttggt aaaaaaaatc
     8641 cgaccagaaa tctgaaaaga taattgcaac cttgactgaa acatgttaag atgttaatgt
     8701 tgtaaatcga caaatcaact ctggttcagc aaatggagca gggcaaagga gcgaaaaaat
     8761 catgaaagaa aacatccatc cagattacca cccagtagta ttcatggatt caacaactgg
     8821 tttcaaattc ttgtcaggtt caacaaaaac ttcacaagaa acagttgaat gggaagacgg
     8881 taatacatac ccagtcatcc gtgtcgaagt aacttctgac tcacatccat tctacactgg
     8941 acgtcaaaaa ttcacacaag cagacggacg tgtggaccgt ttcaacaaaa aatacggtct
     9001 caaagacgca aacgctgcgg aataataaaa acgctgataa ctcaacgttt agcagactat
     9061 ctgataggga tagtctgttt ttttatgttt tttgccaatt taaaacttcg tttgatgctg
     9121 aaaaagtcgt aggatcataa tgcacaaaac aatgaaaaac tagtatatag ttttaattat
     9181 ccacttgata aaaacacctt atattaacga aatgaagagg ggttatttcg aagtaaaaaa
     9241 ccatttacct aaaattagaa gctaagcttt cctttcaagg aaggcttttt gttttgttat
     9301 agacttgcga ttgtttgtga gctagatcgt tcattttaat gacttataca cgcggatgat
     9361 gggtcttttt cctctgttca ttcataatat tgaacggtac agctagcgat gctatactga
     9421 cctcagttcc aagaaaacgt taacattttt tgtgggggag aggtttttta tgaggtttga
     9481 tcaattgatc gcagaagaac tgattgtttt cgatccatcg atagattcaa aaggatcatt
     9541 atttgagcga ataggggatg tgttgaaaaa aacaaataag gtaagaaatg ttcaaaaagt
     9601 cgttaaggca ctattcaaac gagaggagga gatctccaca ggaatagaag atggatttgg
     9661 gattccccat gcaaaaagca aatatgtgac aaaaccagca ctgtgttttt ttcatacagc
     9721 caaattaacg gactatagcg ggatagatga aatgccaatt gaatatattt ttgccatcgt
     9781 agttcctgaa aaatcagcag atatgcatct agagattctc agcacactct ccagacgatt
     9841 gatgaatgca gattttagaa agggaataaa agaagccact acgccagcag atatcatcag
     9901 acagattagt caagaatgaa aatagtagag tctttgtccg agtatcgata gtgaagaaaa
     9961 aggaggaaaa taatcatgaa aatcgttggt gtaactgctt gcccgactgg aattgctcat
    10021 acttatatgt cggcagaaaa attagaagta acagcaagaa atctaaacca tcaagcaaaa
    10081 ttcgaaacac aaggtgtaaa aacagaaaat cagttatctg aacaagaaat caaagaggca
    10141 gatgcaatca ttcttgcagt agataaagaa atcgaattgg accgatttgc cgggaaaaaa
    10201 gtaaagcgtg tctctacaag ccgagcaatc aaagaaccgc aagtagtaat agacgaagca
    10261 ttgagagata ttggcgtatt cgttgtgtct aatgaaaaag aaccagctgc aaatgagaaa
    10321 aagccgacaa tctataatca tttcatgaat ggtgtgaatt acatgcttcc atttgtgatc
    10381 gcaggcggaa tcatcatcgc actgagtttt gcctttggga ttacagcggc tgatcccaac
    10441 tcagcagact ataatgtgtt agcagctgca ttttcaagga tcggaggaga tacagcgttt
    10501 gccatgatgg ttcctgcgtt aggcgcgggg attgctacat cgattgctgg aaaagcaggt
    10561 tttgccccag gaattgttgc cggattactg gcctctacag gtggttcagg ttttcttggc
    10621 ggaatgattg gtggcgtgct agcagggtat atctgtgatt ttctggcaaa taaaattagc
    10681 gtaaaaaaag aattttctgc tatttatcag ctgattgtcg tccccttttt atcgatctta
    10741 attattgggc ttttgatggt atttgtgatt gaacaaccga tcacatgggt gttggatgct
    10801 ttgacaaatt ggctgaatag cttgggaaat acatccgggc tattgttcgg attacttatc
    10861 gggatcatga tggcagctga tatgggtggg ccgatcaata aatcgacttc gactttctcg
    10921 atcggtttga tgtcagctgg agtaaatgca ccgattgctg cttgtatggc tgcaggaatg
    10981 acacctcccc taggtattgc tttagccact ttattattca aacataaatt taccaaagaa
    11041 gaacggactt caggtcaatc atgctggatt ttaggcgctt cgtatattac agaaggtgct
    11101 ataccgtttg cggtatctga cccgatccgc gtgataccta gtttgatgac aggttcagca
    11161 gtcgctgcag ggatttccat ggcagtagga gttacttcaa tggcacctca tggagggatt
    11221 tgggtgatgc taattccaaa tgttatgaac aatttaccta tgtatgtctt ggcaattgca
    11281 tcaggtacag tcactacagc ctttatgctt ggactattga aaaaaacagt gaaagagaaa
    11341 aaacaagaca agtggacgaa aaatgaaaat ctaacaaatg aggtggaagc gtaatgttat
    11401 atacaatgaa agagttattg aaagtggcta aagagaatca atttgcagta ccagccttca
    11461 atatttgcag ctatgatatg atgaaagcaa tcatcgaaga agcagagaga ttagaagcac
    11521 cagtaatctt agaaattcat cctgatgaaa tcgcctattt aagtgatgag tttgttgcgg
    11581 cagtaagagc ctatgcttat acaagtaaac tgccgatcgt tatccacttg gatcatggcg
    11641 gtacgataga agatgtctta cgggcgattc gaaacggcta ttcttccgtg atgatcgatg
    11701 cgtctttgaa atcattcgac gacaatgtac agattacgaa aaaagtggtt gcgttagctc
    11761 atgcggtaaa tgtctcagtg gaggctgagc ttggaacgat tgggaataat ggttctgctg
    11821 aaggaggtgc tgaaacaatc atttatacag atcctgatca agcgaagatt tttgtgaaag
    11881 aaacaggaat cgatacactt gctgtagcaa ttggaacagc gcatggcttg tatccgaaaa
    11941 acagaactcc aaaattaaat atcgacttac tgaaagaatt gaaccaacaa atcgatcttc
    12001 catttgtttt acatggcggt tcaggtaatc cggacgcaga agtcagcgaa gcagtaaaat
    12061 acggagttgc caaagtgaat ttgagctcag atcttaaaag cgtctttttc aatgctttga
    12121 gagaaatatt gagtgaaaat ccatcgatgt acgagccgaa tgcaatttat ccagcagcta
    12181 ataaaaaggt acaagaagtg gtcaaacata aaatggaaat tttgaacaca gtaggcaagg
    12241 ctagtttata ctaaaaataa aaatgtgtgg tcaagagggt atgacaatag tcttgtcata
    12301 ccctcttaac cacacacgat gttcagaagt agttttttcg aaaaatttct tcttatttct
    12361 cgaagccaat cacttctgtc acaacctctt ttttcctgtt actatataaa gtaaatgggg
    12421 tgattttatg ttgaatgaag tggagaatag acagcaggag attgtgaatt atctaaaaaa
    12481 caaccaattt gcaagagtca ccgatttgat cgagttagta aattatagcg aagccacgat
    12541 taaacgtgac cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc
    12601 catgcttatt gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga
    12661 agaagaaaca gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat
    12721 ggtcttattc ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt
    12781 tgatggtttg cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac
    12841 aacggcaaaa gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg
    12901 ttcaaaagcc tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg
    12961 cgggctagat ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa
    13021 agcttttaga aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca
    13081 taaattcatg catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga
    13141 actgacaaaa gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata
    13201 aattattacg tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct
    13261 cgcttctctc agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt
    13321 tttatccagg agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca
    13381 atcatgatct gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg
    13441 gattcaacga ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg
    13501 atcttacgta aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt
    13561 atcttgtggc tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg
    13621 attcctgctc tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa
    13681 ggcatcgtac cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat
    13741 aaatgaaagc tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac
    13801 tcaaaaaacc gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga
    13861 tcaaatttca tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg
    13921 gccattaaca agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa
    13981 tcctctaaat gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc
    14041 taggtctaaa ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat
    14101 ttttaaacaa acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc
    14161 tccagagata agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt
    14221 taagaataaa tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc
    14281 agtcaatgga cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc
    14341 agcaactaag tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga
    14401 aagacccatc aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt
    14461 gatattccat gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg
    14521 aaagacaagg caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa
    14581 acgaaaatca gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa
    14641 actagtactt aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc
    14701 agtaacgata gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg
    14761 aactaaatac aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata
    14821 gaagatcgcg ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat
    14881 gaataagcgt gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct
    14941 caagctggcg tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata
    15001 aatcaggtag acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt
    15061 cttttccatg tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg
    15121 aacttctaca tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc
    15181 tcttgtagac ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac
    15241 tgctttgatc aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt
    15301 catatcaaat cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta
    15361 attcatgttt tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa
    15421 aaaggaaaaa aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag
    15481 taaaatacct ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt
    15541 ttggatgggg gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat
    15601 tttccgatta tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc
    15661 catacgtata tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga
    15721 gaatttaacc ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat
    15781 tcacaattca tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat
    15841 cgaatcaatc gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat
    15901 gtaaaagagt attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta
    15961 ttaaacggaa agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt
    16021 gtgcggacag aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa
    16081 ttttgtggca tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat
    16141 ggtattatca ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac
    16201 aatattatct tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga
    16261 gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    16321 agctgattga acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    16381 ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga
    16441 gttggtagga gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat
    16501 aagaagagcc aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta
    16561 gatgtaagct tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc
    16621 acagcccttt ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc
    16681 aaaagtcccg ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg
    16741 gcttttgggg attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt
    16801 taatttgata ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata
    16861 acgcgaaaca gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat
    16921 gatgatttct actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac
    16981 acgataatgt cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc
    17041 ttttgcagca ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga
    17101 atcgattctg ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc
    17161 acgctgtccc atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct
    17221 taagtaatta tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa
    17281 gactcgtcct ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg
    17341 atctgttgtg aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac
    17401 cggccagcca acacttacta gcaaaagaaa gaataaaaaa aactttttca tcatatcaag
    17461 taacctccga tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc
    17521 aattttttct ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg
    17581 tagtagtaga cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt
    17641 aatacgtaat tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt
    17701 gtatatccat ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga
    17761 atctgtgatt tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa
    17821 tactggcttt taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc
    17881 ttttgttgcg tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct
    17941 gctcttgaaa cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg
    18001 cggataactg taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa
    18061 gggaaataca cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca
    18121 aaccattttt tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca
    18181 aaaggaagta ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga
    18241 ttatggcagt agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca
    18301 cagttgggac aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta
    18361 tctgaaaaac cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc
    18421 tgttcttggg ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg
    18481 ccagccatac gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag
    18541 atattcaggc agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg
    18601 ccgcaattag gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat
    18661 taattaacgg ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg
    18721 ttggaaagat ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg
    18781 ttttctacag gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg
    18841 caaactggac atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct
    18901 gcttgttgtt tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt
    18961 gcattcattc ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg
    19021 gctgcttcca taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca
    19081 cctagcatcg ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa
    19141 atgctggcta cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc
    19201 aatgcagtat ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt
    19261 tgaccatctg cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa
    19321 tactgctcat tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta
    19381 taaaataaaa tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat
    19441 tctgcgttat agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc
    19501 tttatttctt ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat
    19561 ttgaatcggt caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga
    19621 gctgcgtcat ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca
    19681 ccatcgacca aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa
    19741 acatcttctg ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct
    19801 tttgtcatga ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct
    19861 gccagaccgc cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc
    19921 tctgattcag ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa
    19981 acttctcgga ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa
    20041 aagccgagaa ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt
    20101 ttttaaaaaa gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag
    20161 cgtttcgaag acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt
    20221 tcccacaaaa cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt
    20281 gcagcaaaga ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc
    20341 aacgaatgcg aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc
    20401 gatgctgcca gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat
    20461 gcgcctacaa aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca
    20521 ggagctttca atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc
    20581 ttagcaacga ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt
    20641 gattttaaac ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa
    20701 tcgactatca gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg
    20761 atgcgggatg cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact
    20821 ttagatgatg ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg
    20881 agtgcttgcg tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca
    20941 gccggcaaag aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg
    21001 atgtatcagc aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt
    21061 acagaattgg cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc
    21121 gatactcaaa atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca
    21181 gtcaaacttg cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat
    21241 gatcagatag taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa
    21301 ctacgcagta atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat
    21361 aaaaaacaga caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa
    21421 gcgacaagac agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta
    21481 tctgtcactc agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga
    21541 ctagtgattg cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg
    21601 cagctttcgg tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt
    21661 tatattacaa gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa
    21721 gagggaacag aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct
    21781 caagaacaag aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc
    21841 gaagctgtta cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat
    21901 gggcaatatg caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc
    21961 acaagagctg ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc
    22021 ggtttttaca ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc
    22081 tgatgatatc gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca
    22141 aattgatgtg gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta
    22201 gttttaaact gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga
    22261 cagctacatg aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac
    22321 gatcgatatg aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg
    22381 cgatttgcat ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg
    22441 tagaaatcct tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat
    22501 ggcaatggaa aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc
    22561 accgatggaa gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca
    22621 tgatgcagat gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac
    22681 agctatgtat ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca
    22741 tggtctgtct gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt
    22801 cgaaggaaga cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag
    22861 cagcacaaga gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga
    22921 tggtgcagga aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa
    22981 aacagaaatc attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc
    23041 agtgatcctt gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc
    23101 agcagcaaga agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat
    23161 cgttttatgc gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat
    23221 cggcgttacc gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt
    23281 taccctttat cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca
    23341 aaatcaaatc gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc
    23401 ttacttaaag ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag
    23461 ctttgaagaa gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt
    23521 tgaaaactag gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac
    23581 agcaaccgtt tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg
    23641 acaggcggct tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt
    23701 gtagaagaag cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct
    23761 acacctgtta cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa
    23821 gtaggcggtg ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag
    23881 ctgagctatg aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct
    23941 tcaacggagt tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg
    24001 aacaggaaaa catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa
    24061 agacaatctg ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc
    24121 agatgttttg gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt
    24181 gcagacggaa ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga
    24241 agctgaaaaa atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc
    24301 tggagatttt ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca
    24361 atctcgttgt caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt
    24421 gcaagaagag cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt
    24481 aggaaaagca gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta
    24541 tcaatggttc gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa
    24601 attggtaaaa tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt
    24661 ttattatcag gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca
    24721 gataaaccag ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag
    24781 ttttcaggct gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga
    24841 tgatgatcaa ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt
    24901 catatctatt attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc
    24961 gaatctcagc aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc
    25021 aatgaccttc ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa
    25081 aaagacaaaa aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg
    25141 cagttgcgtg agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa
    25201 ttgatttttt ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg
    25261 gccgctgtat ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag
    25321 ataataggcg gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat
    25381 ttcgtgcctg tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa
    25441 atttccggtt tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag
    25501 acagcgaaaa aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg
    25561 aaagtcgtag ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa
    25621 aatcctgtcg aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat
    25681 ggataagaga tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt
    25741 aacagaactt gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt
    25801 ggagatggaa aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc
    25861 tccagctgaa aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta
    25921 tgaagaagga ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc
    25981 ttgtgcgttt tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg
    26041 agactggagc ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat
    26101 aatcaaaaaa gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca
    26161 attggaaatt tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt
    26221 atcgcaagtg aggatacgcg taatacacaa aagttattga atcattttga aatccataca
    26281 ccccaaaaaa gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg
    26341 ttaaaagaag gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat
    26401 cctggacatg agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca
    26461 ggacctacag ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta
    26521 ttttatggct tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa
    26581 gaacagacag ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg
    26641 aattttttag aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc
    26701 catgaagaat accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca
    26761 gtaaagggtg aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa
    26821 gttgatgaag agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa
    26881 aaaccaaatg ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc
    26941 taccgtcagt accatgaatt agactgagat agtataagtt gtctataatg aaagactaat
    27001 gaggaaatca gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat
    27061 gaataagagg tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa
    27121 atcattcata ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag
    27181 tttcgcggac atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta
    27241 gtgactacag caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa
    27301 aaagcgtatg agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc
    27361 gatatttcca aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt
    27421 agtatcgatg aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc
    27481 aaaatcgccc gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg
    27541 ggagtaagtt acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga
    27601 atcacggtag ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa
    27661 tttcatgggg tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga
    27721 aaagacctat atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat
    27781 tctctttatc gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga
    27841 aaatctgtgg gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg
    27901 actcagttgc gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat
    27961 gggaaaacag tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg
    28021 acattgccag aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg
    28081 gaggaaatct tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg
    28141 gacccgatga cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa
    28201 cagctttgag agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag
    28261 tcttgctttt tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca
    28321 acttgattgg attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga
    28381 aattgtagtt ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt
    28441 tgcgaaagga gttctaattt atcttctgaa tcttgtagca attcatcaaa ggcatagcct
    28501 gtccatgacc agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc
    28561 agacaaacat ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa
    28621 tcgttgcgca agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat
    28681 cggaaatttt gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg
    28741 taaagactgt tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata
    28801 tagttttggc tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa
    28861 cttctttcat ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata
    28921 aataagaaca aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag
    28981 ggcgttcaaa gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc
    29041 ttattctgaa taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga
    29101 aaaatatgag gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt
    29161 cacaacctca tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca
    29221 tcggacgagc ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt
    29281 ttggatcatg atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac
    29341 cttcgaaacc acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt
    29401 tgtcatatgc aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt
    29461 attcacagta gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca
    29521 atttttcaaa tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt
    29581 ctttatctgt gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt
    29641 cagttagact ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc
    29701 atgcatctgc attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg
    29761 ggtttgtttc ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc
    29821 ctaacgatac agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa
    29881 gacgtttccc gaaagaacca tacatatata aaattggcgc atttgctgga atggcttctt
    29941 tacaacgttc tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta
    30001 actgccagaa tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg
    30061 taacaacacc taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc
    30121 cttgcaagaa tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt
    30181 tatcgtaatt cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt
    30241 tgatgtcgta attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca
    30301 gtttagggaa gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa
    30361 ttgctttttg aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga
    30421 aaggagtttg tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag
    30481 catcgaagat atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat
    30541 cgatccattc ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa
    30601 gcaattcatc tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa
    30661 taatctgtga gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat
    30721 tgccgatttt gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca
    30781 tcggtgtata aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat
    30841 ttgctatatg tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca
    30901 gatctcgctg tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt
    30961 ggtccttgtt gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa
    31021 aatctcgttt ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta
    31081 gtaatatatg ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc
    31141 ttttgatttc ttggacaacc aagtctgcaa tcatttgatt tttttcataa gtaagtggtg
    31201 ataatgagcc gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat
    31261 cgaaatcaac atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct
    31321 gagtaacgac agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg
    31381 ttcttgtcta tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt
    31441 attcaatgtg ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa
    31501 aaaggtgaaa acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa
    31561 ataattgaat aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat
    31621 tattcgtaga tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag
    31681 aattggaaaa gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc
    31741 ccgtcaaagc cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta
    31801 tgggcccaag tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc
    31861 ctacgatggg cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc
    31921 tcagtgactt tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata
    31981 ccctaaatgc aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg
    32041 aaatggaaaa gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac
    32101 ggtatcccga tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg
    32161 ttgttcagcc acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg
    32221 ctacagaatt gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt
    32281 tagtcaccca tgatccatat acagcaagct actgcgatag aattttattt attaaagatg
    32341 gtgtgatttt ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa
    32401 tagacatgca ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt
    32461 aaaagttttt ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc
    32521 gtaatgatct attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca
    32581 agtcaagata cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt
    32641 ttgctttttt tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata
    32701 ggcatctatc agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa
    32761 atcatgataa ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc
    32821 aaactctttt caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt
    32881 atctccattc catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta
    32941 tctgtatatt caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa
    33001 gaacaagcag atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc
    33061 gggttactac ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca
    33121 tggatgatca gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt
    33181 ttcgtttgtg tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc
    33241 atattgagta aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg
    33301 caagttcatt tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt
    33361 tctttaatga caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa
    33421 gtttcctccc cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt
    33481 ctagcagagg aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg
    33541 agtatctata gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa
    33601 acacaatatc aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca
    33661 cctggtcata ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat
    33721 ggatctagta ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt
    33781 gtattaggtg acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt
    33841 tttgaaaaag caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat
    33901 aatgaaaaaa tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt
    33961 tattattctt atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt
    34021 ccggatgacc aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct
    34081 tccagctatt cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca
    34141 ctatttgtcg ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta
    34201 gcagaagcag aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa
    34261 agaaggatca gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata
    34321 ttagggatca ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc
    34381 gattactggt tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat
    34441 gtcattacga gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag
    34501 ataataaata gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat
    34561 ttttgtcaca acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa
    34621 aagcagtgat ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa
    34681 acggtttctg taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga
    34741 ggttatatga ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg
    34801 gggaaaattc atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct
    34861 gtatcactat aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga
    34921 gtatggaaat caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc
    34981 gagttgctta tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg
    35041 cacttgctta ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca
    35101 atttggagtt tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt
    35161 tgccgattga agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac
    35221 catctatggt catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa
    35281 caaaaaaaga atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg
    35341 taaaaggtac agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag
    35401 gcgtacaaat cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg
    35461 ggatcaagcc tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat
    35521 tttctattta tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg
    35581 ttcaagactt tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt
    35641 ctactccatc atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc
    35701 cggaattgga catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc
    35761 tacttgatcg attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg
    35821 tagctatttc aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga
    35881 ttggctacgt aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa
    35941 aaggagaaac gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca
    36001 atcccgaaaa gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag
    36061 gggatgcagg tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc
    36121 aggtcaaatt acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag
    36181 acaaccgaat caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc
    36241 tggttgcttt tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat
    36301 ctatcaaaga acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt
    36361 atgtcgatct gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg
    36421 aggtgaatcc tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt
    36481 tcttttagcc attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt
    36541 accagtttat caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta
    36601 ttggcaacag ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg
    36661 ctattttgtt tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt
    36721 agcgataatt ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc
    36781 gttacttggt tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga
    36841 aataagagat ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt
    36901 ctttccaaca atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct
    36961 ccatccgcct gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt
    37021 tgtcggtttt ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt
    37081 agtgggacgc attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta
    37141 cgtgtacagt atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac
    37201 aagctacatg atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa
    37261 tatcaaagaa ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt
    37321 atatatgcga ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat
    37381 gtcaaatatc ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg
    37441 gtactacatc gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat
    37501 ccgatttaag aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc
    37561 cgtatttttg acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga
    37621 taaacttttt tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg
    37681 aaaatggaag aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga
    37741 aaaaatcgtg atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa
    37801 ttattagtcg agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga
    37861 gaggattgga gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta
    37921 tgaaaaagaa actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg
    37981 tgttttttac ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct
    38041 cttcttccat gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg
    38101 aaaaacaata tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc
    38161 cgtctgttct ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg
    38221 ggacacaatc gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca
    38281 agaaagtcgt ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt
    38341 actttaatac gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag
    38401 taacgcctgc tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga
    38461 atgatacgtt gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat
    38521 ctttgaatca gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca
    38581 atattgggtt gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac
    38641 aataccaaga aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga
    38701 ataatccatt cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag
    38761 agctcaaaca gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc
    38821 agctggtctt ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg
    38881 ttaacgagaa atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca
    38941 aaaagatcaa atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc
    39001 aagcgggtac caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg
    39061 ctgcagatca acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc
    39121 atcttgacga tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat
    39181 taaaataaag aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga
    39241 ataaaagata aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca
    39301 atatgaatat agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga
    39361 tttaacttct gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga
    39421 atatgccaaa ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa
    39481 acatggtgct ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt
    39541 tatggtaaca aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg
    39601 ggggcaagtc atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca
    39661 cggtgtgatt ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta
    39721 tgaaataaag gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg
    39781 gggcatacgt cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag
    39841 taaatattta ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt
    39901 attagagaat ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca
    39961 agaagaagta ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc
    40021 ttttgcttta gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga
    40081 ttcgatttta ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa
    40141 aaaattattg aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac
    40201 agtgatttct ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc
    40261 gtctgtagcc attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga
    40321 agatgattat ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga
    40381 aacagttgaa aaaattcgga gttatgaata atgaataata gaatacctat ttctgaatat
    40441 cggaaaaaag cacgagtttc tttggaaaat caatggggaa tcaatacttg gcttgttttc
    40501 ttatctataa tatttacgag cgtcatccag aacttttttg acggtttcag tccttttccg
    40561 gaagaaagca tgcagcagca cttattgagt tttctagtcg ataatttact tttattcgca
    40621 ttcaactatg cattgtttta cattgcgcta gtagttgtac ggggtggcag accaaaaagt
    40681 aaccttttat tttcagtttt ccaaagaaag tattttggtt cgatacttgg catcaatttg
    40741 atcaattcag tcatcaactg gctactcaac agtttaatct ttctgcccat gtttttaatc
    40801 agcggagtga gtacttatat gcagctgctt ttcagttcaa atgcggtacc tacgggtgtc
    40861 atgccagaag attttcttga tatcagcttt gttttatcga tgatagggat gatttttgtt
    40921 tcagcactca tcatgagtat tgttggcggt ttattccaat ttgctgcatg gacaaagttc
    40981 gactatcctg atttgtcggt tattcaatgt ttgaaatatg gctggttttt attgaaagat
    41041 agaattggta cgtatatttt gttgcagctg tcttttatcg gctggtattt gctaggagca
    41101 atcgctttgt tcatcggtct tttgtgggtc attgtttatg tgaatgtgtc agttgcagaa
    41161 ttttatgaac aagcacggat tgaaaaagga ggtccagacg cctattttac ttagcatgta
    41221 agcagtttat tcatcaaaaa aataactttt gtggtaggat aaatctttga gggggaatgt
    41281 acgatgaaat taactgtttt aggatgctta ggagcgtatc cttataaaaa tcaagggaca
    41341 acaggttatt tgcttcaatc tgacgggttc aatttgttga tcgatgcagg tagtgctacg
    41401 ctgatcaaat tacaagaaca ccttgatcca cttgatctag atgctgtgat ccttagccat
    41461 tatcatcatg atcatattgc tgaccttggt gtattacagt attactggca acttcatcct
    41521 aagagaaatc cggagacatt gctttcaatt tatggacaca caaaagattc cattcacttt
    41581 gaagaattga cgttggaaaa tgtctcaaaa ggacatcctt attttgaagc tgaagaatta
    41641 aaaattggtc cttttctgat tacttttatg gaaacaatcc atccagtagt atgttacgcc
    41701 atgcgtatcg tagaagaaac aacggggaaa gtattcgtat ttacaggtga ttcaggttat
    41761 ttggaaagtt tcgctgattt tgcgaaagat gctgatttgt ttctagcaga tacctatctt
    41821 tttgaaggaa atgaacatca tcatgcccat ttcacttcaa aagaagctgg agaacttgcg
    41881 aaatcagcta acgtaaagaa acttgtactt acacacctac ctcagtttgg tgatttagaa
    41941 caattgaaaa atgaagcgca aaaggcagca ggcaaaggga ttgatataga acttgctgca
    42001 gttgacaaag tgtttaacat ttaggaggaa gaacatgatt tttgtaccaa atgaaaacca
    42061 cgacccaaga atcaatttag caattgaaca atatttgctg caagaaatgc ctttagatga
    42121 acctattttg ctcttttata tcaatgaacc ttcaatcatc atcggcagaa accaaaatac
    42181 gcttgaagaa atcaatcgag attatgtgga agaaaatggc attcatgttg tccgtcgctt
    42241 aagtggaggc ggagctgtct accatgattt tggaaacctg aactttagtt ttatcatgcc
    42301 tgatgatggg gattcattcc gtgactttgc gaaagtaaca cagccaatca tccaagcact
    42361 tcatgaattg ggtgttgctg gggcggaatt gaaaggccga aatgatctag tcattgatgg
    42421 catgaaattt tctggcaacg cgatgtatgc taccaacggt cggatgtttg ctcatggaac
    42481 aattatgttc gactctgata tcaatgaagt agtcaatgca ttaaaagtaa aaaaagacaa
    42541 aatcgaatca aaaggaatca aatcgatccg ttctcgtgta acgaatatca aaccatttct
    42601 tccagaagaa aagcaaaaaa tgacaacaga agaatttcgt caagaaatct tgttgaaaat
    42661 tttcggcgta gagtcagtag aagaagtaaa aacgtacgaa ttgactgatg aagattggaa
    42721 aaaaatcaat cgaatctctg aggaatatta tcgaaattgg gattggaatt acgggaagtc
    42781 tccagatttc aatttctctc gccaaaaacg tttttctatc ggttcgattg aagtccattt
    42841 gaatgtctca gaaggaatga tcaaagaagc aaaaatcttt ggcgatttct tcggactagg
    42901 agatatctct gacgtggaaa aaaaattggt tggacagaaa tatgataaag catctctatc
    42961 aaaaatagtc agccaaattg atgtgaagaa atattttggt gcgatagaac cagaagaatt
    43021 gcttacctta ctttattgaa aataaaaaat agcggaatcc acatatatgg attccgctat
    43081 tttttataca ggattcgggt aatttcgaga gagttgaaca gtgatccgat caatgaaagt
    43141 atctttttcc tgcgttagtg ttcctgtgta acgatccgct acgtctttca tcatcattaa
    43201 gtcaaaacgt tcctgatcat ctaattcttc tgtgatgcct cgactaaata ggtttgtatc
    43261 gtaatgtgca ctatgttcgc aacaaatgac gaaatgttcc tcttgttcgt gtatcgacaa
    43321 ataaattttt cgatacagtg gattttcgat ggcatgagtt tctctaaagg aatgctctaa
    43381 agcgtggatc aaaagttgag ccagatcgtc atcgttgata ggaagttctt cgggaagatc
    43441 tgcttggaag gttatctgaa tattccgttt ggcagctaac ttctggtaac gcgctaagat
    43501 aagatttgtc acctggtggt tgcaaaaaga acacagcatt tcgaaatttt ttgcttcttc
    43561 taatatcttt tccacatagt ttttagcttt tgtttggtcc gtatgcatta aatcttgcag
    43621 attctccatc tcttggacaa attccaggcg aagtgtattt acttcttgga tatgctgtcg
    43681 aagctgctca taatgttgct ccaacaaatc atttttgatt tttaagaaat ctacttgtct
    43741 ccgatctttg tcggtattta agatgtgatc gattagattg tagctgataa taacgattag
    43801 aatgataata tataaaatcg tagaccaatt gatcgttgtt tgatagatac ctaatgccgt
    43861 ttggatgtaa atcaagcaat ggataatggc taccaagacg atccaaggtg tacaagctac
    43921 ataaaaacgg ttattcttat atgcttcgcc aatgcatgca agtgaagtga ctaaagtgct
    43981 tataacacta gcaatattag caatcggcat taattcagga agttctgcag gagtaaaagt
    44041 tgcataaagc agaacgccga taaaaatcaa aagttggaac gtacaaaaaa ttccgtacca
    44101 ttttttatag taaaacattc ggctccaata gtagcagatg atgaaagctg acgttaagat
    44161 aataaataaa tgagataaaa aagaatgaac gaatggttca aaaagaatac cacttaaaat
    44221 atcttctgat acagcttcaa atcctaatgc caaagcaaag caacttaaga gaataagtga
    44281 gtattcaaga cgtttttgtt tatacatcaa gtagatcgta tagaaaaagg tccctatagc
    44341 gataaaaaca gcgattatca tcgtcaatac ttgcggcact gattgtgaat aaataaaact
    44401 aatcaatggt ccagttgttc ctagataaac tttcggtggc agtccagcat agttctgata
    44461 aggagatgag actgtaaggg tcaatttttt tccgatataa tttgctggta aatctatcac
    44521 agccaatgag agtccgggat tgctttcttc ctgataatct ttccgttggt ataaaatctt
    44581 ttcgcctaga tatacagtaa tccattgatg gtttcctttg attagtaaat ttgcttcgtc
    44641 caacggtttt tcaagtgtcg tttccataat gaatgtttcg tctttatcca cggtaggaat
    44701 cgtacgagtg tacttgctgt caaacttaaa atcaggatca tcttttgtat agaaaaccca
    44761 cgaatctttt atttctttca tttgattgct gtccgcagga gaaaaaataa aataaaagaa
    44821 ataagcaatt cctgttaaaa ataacaatga taatataatg attatgctcc actttatacg
    44881 taaataaaaa gattcttttt tattatatat gttattaaaa aaagacataa aggtattcct
    44941 ttctaaaact tgtaatgtta gggtaaacgt tttttaaact aacgtcaatt atttataata
    45001 aaaaatgaga ta
//
LOCUS       DACGDM010000015        40947 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.015, whole genome shotgun sequence.
ACCESSION   DACGDM010000015 DACGDM010000000
VERSION     DACGDM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.015"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(232..1014)
                     /locus_tag="IXR05_000906"
     CDS             complement(232..1014)
                     /locus_tag="IXR05_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259444.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1079..1915)
                     /locus_tag="IXR05_000907"
     CDS             complement(1079..1915)
                     /locus_tag="IXR05_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4259445.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(1933..3342)
                     /locus_tag="IXR05_000908"
     CDS             complement(1933..3342)
                     /locus_tag="IXR05_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4259446.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3356..5179)
                     /locus_tag="IXR05_000909"
     CDS             complement(3356..5179)
                     /locus_tag="IXR05_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4259447.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6022..6348)
                     /locus_tag="IXR05_000910"
     CDS             complement(6022..6348)
                     /locus_tag="IXR05_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259448.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6394..6756)
                     /locus_tag="IXR05_000911"
     CDS             complement(6394..6756)
                     /locus_tag="IXR05_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAQ4259449.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6793..7008)
                     /locus_tag="IXR05_000912"
     CDS             complement(6793..7008)
                     /locus_tag="IXR05_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4259450.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            7135..7470
                     /locus_tag="IXR05_000913"
     CDS             7135..7470
                     /locus_tag="IXR05_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4259451.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7546..9543)
                     /locus_tag="IXR05_000914"
     CDS             complement(7546..9543)
                     /locus_tag="IXR05_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259452.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9641..9916)
                     /locus_tag="IXR05_000915"
     CDS             complement(9641..9916)
                     /locus_tag="IXR05_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4259453.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10148..10882
                     /locus_tag="IXR05_000916"
     CDS             10148..10882
                     /locus_tag="IXR05_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4259454.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            10921..12063
                     /locus_tag="IXR05_000917"
     CDS             10921..12063
                     /locus_tag="IXR05_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4259455.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12158..13549)
                     /gene="sufB"
                     /locus_tag="IXR05_000918"
     CDS             complement(12158..13549)
                     /gene="sufB"
                     /locus_tag="IXR05_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAQ4259456.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13554..14024)
                     /locus_tag="IXR05_000919"
     CDS             complement(13554..14024)
                     /locus_tag="IXR05_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAQ4259457.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14011..15246)
                     /locus_tag="IXR05_000920"
     CDS             complement(14011..15246)
                     /locus_tag="IXR05_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4259458.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15243..16529)
                     /gene="sufD"
                     /locus_tag="IXR05_000921"
     CDS             complement(15243..16529)
                     /gene="sufD"
                     /locus_tag="IXR05_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAQ4259459.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16542..17315)
                     /gene="sufC"
                     /locus_tag="IXR05_000922"
     CDS             complement(16542..17315)
                     /gene="sufC"
                     /locus_tag="IXR05_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAQ4259460.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17512..18360)
                     /locus_tag="IXR05_000923"
     CDS             complement(17512..18360)
                     /locus_tag="IXR05_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259461.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18384..19070)
                     /locus_tag="IXR05_000924"
     CDS             complement(18384..19070)
                     /locus_tag="IXR05_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259462.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19063..20097)
                     /locus_tag="IXR05_000925"
     CDS             complement(19063..20097)
                     /locus_tag="IXR05_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4259463.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(20492..20830)
                     /locus_tag="IXR05_000926"
     CDS             complement(20492..20830)
                     /locus_tag="IXR05_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAQ4259464.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20832..21188)
                     /locus_tag="IXR05_000927"
     CDS             complement(20832..21188)
                     /locus_tag="IXR05_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAQ4259465.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21194..22381)
                     /locus_tag="IXR05_000928"
     CDS             complement(21194..22381)
                     /locus_tag="IXR05_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4259466.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22572..23417)
                     /locus_tag="IXR05_000929"
     CDS             complement(22572..23417)
                     /locus_tag="IXR05_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4259467.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23651..24616
                     /locus_tag="IXR05_000930"
     CDS             23651..24616
                     /locus_tag="IXR05_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAQ4259468.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            24993..26036
                     /locus_tag="IXR05_000931"
     CDS             24993..26036
                     /locus_tag="IXR05_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAQ4259469.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26098..26562)
                     /locus_tag="IXR05_000932"
     CDS             complement(26098..26562)
                     /locus_tag="IXR05_000932"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAQ4259470.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26808..27755
                     /locus_tag="IXR05_000933"
     CDS             26808..27755
                     /locus_tag="IXR05_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4259471.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(27966..30038)
                     /locus_tag="IXR05_000934"
     CDS             complement(27966..30038)
                     /locus_tag="IXR05_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4259472.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(29971..30348)
                     /locus_tag="IXR05_000935"
     CDS             complement(29971..30348)
                     /locus_tag="IXR05_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAQ4259473.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30477..31037)
                     /locus_tag="IXR05_000936"
     CDS             complement(30477..31037)
                     /locus_tag="IXR05_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4259474.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            31187..32479
                     /locus_tag="IXR05_000937"
     CDS             31187..32479
                     /locus_tag="IXR05_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4259475.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(32539..33657)
                     /locus_tag="IXR05_000938"
     CDS             complement(32539..33657)
                     /locus_tag="IXR05_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAQ4259476.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33671..35092)
                     /gene="arcD"
                     /locus_tag="IXR05_000939"
     CDS             complement(33671..35092)
                     /gene="arcD"
                     /locus_tag="IXR05_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAQ4259477.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35338..36459)
                     /gene="mnmA"
                     /locus_tag="IXR05_000940"
     CDS             complement(35338..36459)
                     /gene="mnmA"
                     /locus_tag="IXR05_000940"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAQ4259478.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            36863..37462
                     /locus_tag="IXR05_000941"
     CDS             36863..37462
                     /locus_tag="IXR05_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAQ4259479.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37600..38886)
                     /gene="efmA"
                     /locus_tag="IXR05_000942"
     CDS             complement(37600..38886)
                     /gene="efmA"
                     /locus_tag="IXR05_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAQ4259480.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLTGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(39157..39501)
                     /locus_tag="IXR05_000943"
     CDS             complement(39157..39501)
                     /locus_tag="IXR05_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAQ4259481.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39638..40774)
                     /locus_tag="IXR05_000944"
     CDS             complement(39638..40774)
                     /locus_tag="IXR05_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4259482.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
BASE COUNT        11758 a         8622 c         7169 g        13398 t
ORIGIN      
        1 aatttcttaa aaattttttc actaaaatca ctacctgaaa cagtctaaaa cacttatata
       61 tcaacgttta atgaaactat ctccgtttca tttcagatac aaataaatat agtcgggctc
      121 caaatccgaa aaaaaatacc cccagtagct tatcctaagc tactggagat gtataagtac
      181 ggtcatataa caacggggta gggtaaataa atgaaaaaga tggaagaatc attattcaat
      241 aactttttta aatacttcgt tgtaatcagt tacctgtccg ttcttaaata ccacagaata
      301 atcttttttc ccattttcaa gtaaccgaag tggaatgtct ttaccaactt gctctgtcac
      361 tgcattactg atacctgtta gattagctaa taaatctgat aaagattgag catctgtaga
      421 aatctctgta tcagtattta tcgtgattcc tttatcttca tttacaagct tccaagtagg
      481 tggtatagct gtgtatgttt cgatgaatga atcaattctt tcatctatcg tcttcccagt
      541 atctacttct gtctcattac tcttagatga atcgattctt tcatccatcg tctgctccgt
      601 aactgcttct gtctcattat tctcaccgga aactctcttc acacccaaac ttatatattg
      661 tccatcttta gtgtgcatag ttaaaattcc cacgctttta ctaataaatt cactataacc
      721 agttctttca atagagactt caatgtattt cacactatca tactcaaaag aaaaatagac
      781 atgtaaaagc attttgttgt ttacatctac ataataatcc tttgactcta cttgagacct
      841 tcctatacgg aatacagctt tactgtctga tatctctata ccagcatcct tattattaat
      901 ctgccaatct ccaagtagct cttctggcaa gctagtagtt tcttgtgaac actttaccac
      961 ttcactggta gaggtcgaaa cattcacctc cgcactgtta gaagaatttt ccaaggaatc
     1021 aggagcctta gcacaaccaa caagtcttta tatattgtgc agccgatatt ttcttcattc
     1081 agtacaccct tgaaatatgc agtgttagat aaagcagttc gtcctgattt gctgaggcac
     1141 ccatctcttc ttgaacgtac tccttgattt tcaaggccgc ccgatactct ttcggaaaac
     1201 gctgcttcac tgaagccagc aaaaaatcat ccttctccgg caactcttcc ttcttaatca
     1261 ttcgggcaat aaaaaactgt aaatgcgtca caaatcttaa gtaaagcatc gaatctttat
     1321 caaccttttt ttcgggaaac agatatccta gcatagccaa gatatccttt agtgctctta
     1381 ccgagagcat ggtttcttcc atatttgctt gttcactttg ggcatttaca atgtgaaacg
     1441 caatgtttcc agcctcctct tctggcaact gaacattcat ttttttgttg atcaattgga
     1501 tagcatagca gccgatctca aattcttttg ggtaatactt ttgaatttca atcagcaggc
     1561 gattttgaaa aacaatgcct ttttgactgc gttcaatggc atgcttcaag tgatcaacca
     1621 aggtaaaaaa tagactttta ttcagcttaa agtcaaactt ggcgttggca taatcgataa
     1681 ttcgcttgac gcaaataatt agatcatccg gagcagcctc aaacagttta atgtaatcct
     1741 tttttagagc atcagaaagt gaatctaatt taaatacttt ttggattttg tcagccggaa
     1801 ccaaatcgcc tttctttagt tgaaatccaa tccctttccc catcaaaatt acttctttgc
     1861 cttgcttatc taagcaaaga attaaactgt tgtttaacgt tttaattact ctcattagat
     1921 tcaccgttct ctctaagcta agccatttct tgcgattact ttttgatacc aaaagaagct
     1981 ttcttttttt attcgtttta attctttaag attctcatcg gttcggtcaa catatataaa
     2041 accataacgc ttattgaagc cttgatgggt actaacaaca tcaatcgctg accaaggtaa
     2101 ataaccaaaa acatctacac catctgttaa agctgcttga atagccagaa tatgtttggc
     2161 tagataatca attcgatcct ggtcattaat tcgtctatct tcctcaacta tgtcgggtgc
     2221 cccatagcca ttttcagtaa ttaaaatagg taaatcatag cgatcgtaca atttcctcaa
     2281 tgttaatcgt agtccagtag ggtcaactac ccagccatat ggcgttttat ctacataagg
     2341 attttcagct gcccggtaga caccttcttc tcccaacatg atctgttgat cccccgctct
     2401 agcggaaaca tctgatccgt catttttgct ggcagcgatg gtggcagttg aataataatt
     2461 aatcgcaata aaatcgggtt taccggagga taaaattgcc tgatcctctg cctcaatttt
     2521 aggatataat ccacgatcat tcaaatagtt ttcaaacaaa taattgtatt ttccccgaac
     2581 tgctacatct aagaaagacc agcctctcaa tgtttcccaa ttatgggctg caattgcatc
     2641 ttctggactg gaggtagctt gatacatagc cgttaaattg attgctggac cgatttttcc
     2701 tttaagattc aactgatgat acaagtgaat tactctagct tgagctaata aaacatggtg
     2761 attaatttga aagagttctt tttttgaagg cagctctcca cttggtggca aaccaatcgc
     2821 tccaggatga aggatcatcg tgttttgctc attaattgtc agccaatagt tcaccttgtc
     2881 accatactca gtaagcaata cctgtacata gtccacaaaa taatcgatag ttgctcgatt
     2941 taaccaaccg ccctgctcct ctagaaaata aggtaaatcg aaatggtaca tggtgacaat
     3001 cggttcgatt ccctgattca ggcattcatc aattacttga tgataaaaag aaattccctt
     3061 ttgattggtt ttattatttt caatatccat aattcgcgtc caagcgatgg aaaagcgaaa
     3121 agcttttaag cctaattctt taaacagctg tatatcttct ttatagtgat ggtaaaaatc
     3181 cgaggcaact tcaaaattag ctaccccttc tgtatgctga tacttgtcaa taatagacgg
     3241 ttgtttccca tcctcctgat aggcaccctc tgcctggtag gcactaatgg aggcacccca
     3301 taaaaacttc tctggaaatg ctgaaagctg tttgtattgc acaaaaatcc tctccttaac
     3361 taatttgcat caatggttcg tgttccttta agcttccgct tgcttcacta attcctgcgt
     3421 aattttcact gttggtcact accacaatca ctgtatcatc gtagccagcg tttctaatgg
     3481 cagcgaaatc ggcgttgatt aataattgtc ctgctgacac ctgatctcct gcttttacaa
     3541 atacttcaaa gggttcccct tttaaattca cggtgtcgat ccccacatgg atcaataatt
     3601 caataccttc tttagaacgt agaccaatcg catgtttaga ttctaaaata gtaatgactt
     3661 ctccctcaac aggtgaataa atgctgtttt cttctggatg aatggctacg ccctttccca
     3721 atagtccctt agaaaagaca gcatcgttca cttcagaaat aggacacacg gttcctttta
     3781 ccggattttc aacaatgact gcttcggcta ttgccgtttg ctctgattca tcagaagtat
     3841 cgtcaaatcc aattagataa gcaatgataa aggttgcaac aaaggcgatt acacacgtaa
     3901 taattgcgtg aacaatattc attggatttt ctccaataaa ggctggtaag gctgctaagc
     3961 caggggaaac aaaggcatat ctgactaaac cgctcaagcc agcatacaaa ccagcaattg
     4021 caccaccaat catggaagca actaatggtt ttttcagctt caaggttact ccatagagtg
     4081 aaggctcagt aattcccatt aaagcagtga tcccagtgga cacagctagc tgcttcaact
     4141 ctttgttttt agttttcgcg gctacagcaa aggtagcacc tgattgagca atattagaag
     4201 ccagcattcc tggcccattg atcatttcag aacccgtact gctcaattgc atagtagcga
     4261 ttggcgtcat tgcccaagct gtacccgtaa ccaccaaaaa tggctgcaaa ccacccatca
     4321 aaaatggaat taaccaagct gctttgccgt taatccattc agcccccatt gctataagat
     4381 cgttcagcaa cgttccaaac ggtccaatga caaccaacgc taaaggcccc ataattaaaa
     4441 ataccagcat cggcttagta aagaatttaa taaacgaagg cgaaattcga tccgcaaagg
     4501 gctctacata ggacatgatc caaacagtaa agataatcgg taaaactgat cccgcataat
     4561 ctgcagctaa taccggaatt cctagaaaag aaacggcatc gccagtagaa aaaagctgtg
     4621 aaatatttgg atgaagcaaa atgccagcaa cagtaatcgc caaaattggg ttgacatcaa
     4681 actttatggc tgccccatag gctaatagta ctggcataaa ataaaaggct gcatcagcaa
     4741 tagtattcaa aatgatgtaa gtttgactac tgtctgatag tacaccagtc aaagtcaaga
     4801 cggccaaaat ggcttttacc atcccggcac ctgttatagc tggaatcatc ggtgtaaagg
     4861 tggtagaaat gacactaatc aatcttgaaa taatactttc ttgattgtct gaagaggggc
     4921 cctttttaat tgaagttccc acttcctttt gaatttcctt gaaggctgtt tggacttcat
     4981 tgccaatcac cacttggtat tgtccaccgc tatccaccac actaattaca ccaagtgttt
     5041 tttctaaggc tttcgtatcg gctttccttt tatctttgag ttcaaaacgc agtctggtgg
     5101 cacaatgggt taagctgacc acattttctt ttcccccaac ctgttgcaat acatttcttc
     5161 ctacttctct gtaatccatt attctctctc cttaaagcag taaaaaagac caagtcaaac
     5221 cacgccccaa tcaacattga agtgttagtt tgtcttggtc ttgcctgcat aatcagtaac
     5281 atgccaataa cgttattttg ctgtaatcca ataatagcac attatgatag cgcaatcaac
     5341 agggaattta attttttatc ttttcgtttg accgtatagg gtaatataac agttagatca
     5401 catcaactag ggtatatctg cgtatactta ctgctaaaat aagtatatct aatattaact
     5461 ataccagtaa aaccattcct acataaccag cgggaaattc ccaaaatcgt gaaagcatca
     5521 aaaatgcata taacggatca cacaacttca acaattctgc tcttgggaaa aattgatgaa
     5581 tttggtgagt aaaggatgga ataaacagca ttccaacaat ataggcaaca atagtgatac
     5641 ttgttttttt ggtaaaaatc agtaagcaat agccaatttc aatcattccg agatataaag
     5701 gtatcgatag aatgatttgg gctagtattc ttaaaaatta actagcaaat gtttaaactg
     5761 atttatttct aatctacatg tagtaagtat ttcaattcca ccaattatca ataaaaatac
     5821 caaacatatc cataataatt ttttcttttt catttctttt atattgttat aacagtgaat
     5881 aacataaaaa ttcccgacaa tcattgtaat atttttttgt cacctgtatt agtatttaat
     5941 ttataggaaa ctataaaaac tccctagtga atttacacct ttgggagttc ctgtttggac
     6001 ggtatgcata atacatttaa atcaatttaa cattaacacc tcagcatatg gtatctccac
     6061 atatatacgg tctttctttg gatagtactc aatatttatg ttgatagcac ttccattgtc
     6121 taatatagct ttagcccggt atgtgttatc tccattttca tgagtaatcg tcacatcatc
     6181 acatgatcga tttaagttgt actgttcttg taaaatctgt gttaccaatg gttttgatga
     6241 cttctctaat ccagatgtac ctgtcatttt tgaaaaaata atacctataa tagccaagac
     6301 aacaatacct ataatgacaa acttcttgtt catatttact ttattcaact ttttatctcc
     6361 tatctccaaa ataatttgct cttatccctc ttatcagtac attgacatcc ctaaaagtac
     6421 accaaagatt gctccagcta cccctgctat catcaaaatc gtacccattt tctcatcttt
     6481 ttctcgatat aagtagccca taataacagc aacagcacca aatacaacag gaataaatgc
     6541 taacgatact accatagaaa tccaaccaat aatcaaatac agcttccctg tctcttgtcc
     6601 atgtacgatt tgttccttca tttcattaat tgtctgctca gtacttttct ttactgtgtc
     6661 tgttccggtt gtctcatctg tttcttgtag tgctccacaa aactggcaat acttactttc
     6721 atctgttatt tctttgccac attttctaca atacatgtct tctcctccta aaatcattca
     6781 attgcttatt agttaactgt ttactttatt aaatacatca gaaaacagct cattcattgg
     6841 tacacttaat atctcagaaa gcatcttcat ttgatagggt ttaggaatcg ttctccctgt
     6901 ttgccacgaa cttacacatt gctgtgtaac attcattttt tttgctaact ccgtttgaga
     6961 aagtcctttt tcttttctgt atcggctgag attacttact tttttcatga ttctcccctc
     7021 ctgttttatt atatacaaca atatgatgta tttcaactca taaaatataa aaaacttcaa
     7081 ataccattac aaatacaaca acttgttgta ctatactgag atgggggtgt attaatgaaa
     7141 cagaaacaat atgcaaaggt cattagagaa aagcgaaaag ctctcgggtg gacacaaaaa
     7201 gaattagctg aaaaaatctt ctctacacaa caggcagtag caagatggga aaattctgta
     7261 acagagccta acctcgatag cttaacagct ctttctagag ccctaggaac ccctgtaagc
     7321 cattttctag acaatgttgt cgtagattat gaggaagagt ttttggctct ctatcgttct
     7381 cttagcactg aagatgcagt tcgaacaatt gactatatga agctattaaa aaggcaagaa
     7441 aatgaacgca atcagctatt gaaagattga aaaataaata acccaccgaa ctttaacggt
     7501 gggtgtattg agatgaaata agattaagag ctatggataa cctgtctagt ttaatacaat
     7561 tgggtctttt ctcttcctta ctctccgtcc atcatctctt gttacacttg taaattgata
     7621 cagaggaact atcccagctc ctgataatat caattctttt attgtttcat ctatccctgc
     7681 ccctttcgct aaatatatta aaaaactact acttgctttc acattgtata gtttcttaat
     7741 atccttagaa gctcgttcaa gagtgaatcc ttgtttaaca aagtagcctc tgttttttat
     7801 taaagcattt ttcacgctgt tatccccaac attacgtagg cgttcacaaa cagtgttaat
     7861 aagttctttc tctgtcatta gatatgtccc ttgccacgat aagccctgta aaacttcatg
     7921 tgcttcatct aaaatcaatt gtttttcctt gctgagttct gatcgggaat tttgaggaaa
     7981 tactctttta gcctcttttt cgttaaaaca tatcttaacc cattcataag aaaaatattg
     8041 atatgtaaaa tgaatttttt ccagaagtgg aaggatatct tcattcaatt tttgaatcac
     8101 agaagttgca ttaaaaacgt ctaatcgata gacattgctt ctcttatgat taaagtttcc
     8161 taacgctttc tcttccttta acctatttag gtattcgagc atcttcaaag gaacatcttc
     8221 atcatctaat ttttttatca atcctataaa agtcataagt gatagtaact tattacattt
     8281 atctatgtca taagttttac catagtaaga actcattttt ttagctaatt gttcccccga
     8341 caaaatacaa gtcacacttt ccttactatc atcaaaaaaa ttaacatcag aaagcaagac
     8401 atcatagaca cgtcgcattt cctctagata attccttatt gtcctgaaaa gtttgtcttt
     8461 cattgattca agagtgtcaa aaagtacttt tgattcctct ttcaattttc gaaaatgtgt
     8521 aggatacaag tctaggttct ctaatagcca attaaatgtt tctacccgac tgtctttctt
     8581 taaaattagc atcacaactc caataaaatt ttcactgata tcacaattac tggaatgaca
     8641 ataaaaaatg gaatgcccag ttttactggt aaaaatacta gcagagggat tatgatcgtt
     8701 gtgaaacaga catcttaagt ttttacttga cttaagtaat ttattcatat caatggttaa
     8761 caatctttca taaatctcat taaaagacat gtcggaggaa tcaaacaggc agtctttaaa
     8821 ccactgtttc atttcttctt tgtcgtcatt ttttatcaac ttaacaaaat cggtttcatt
     8881 gactagttca tactctctcc ctgaatcact ttgacaattt ttagaacatg tcatggtaaa
     8941 atcaatcgga agctcagtaa tatctaacat gttgtcttca ttaattatta tcactgcatc
     9001 tgacttatat cctccaaaaa acattctatt cgaagcattt acattgtcat cacacccggg
     9061 gatgttcttt ttcaagtatt cgtaaacagc aaccatttta ccatagtcag taattgcttc
     9121 ttttaataga aagacaatct tgtatttttc tagattttca gagtaccgaa tacttttttg
     9181 tatcgcaaac gcagaattat gaactaaatt gatagataaa accttttcta cgcttaagta
     9241 tctactatca tctttactca aatctactac cttccccttc tcatctttaa cagtgttatc
     9301 gacatccaga ataattactc tggtttccac aaaactctcc ttgtcattgc ctttattctt
     9361 tgtcttgctt ggaataaatg attgtgatga atttagtatc tctacaaact catctcttgt
     9421 aacttctcta tagttatcta aacacctatc tcttacatca gttttttctt tttttgtaac
     9481 tggcttctct aataattttt cttgatctac ataaattgga atattaatca ttgatgtttc
     9541 catttgtgtt tcctccttat aaaattctgt taaagactaa aacatacaga taataaaaac
     9601 aaactcttta ttactatatg ttttagtctt atttgtttac tcaaccttta taccgttcca
     9661 tgaaactatc aatatcagat tttttaaatc taatgaccgt atcaattttt ataacaggta
     9721 acccgtattg agaaacatat tttctaatcg ttcctactga tacacctaga tattcacttg
     9781 cctgctgata gtccatatac tctagagtga ctccagaaat aatgtcttct agcataggct
     9841 ttagcactgt aattatctct ttcacttgtt gttcaacttg tatagaaaca atgctatcaa
     9901 tgatttgtag agacatattt ccccctcctt tcgtgattgc ttgaacaaat tttctaagaa
     9961 ttatcttcgt attttttgct caaaataaaa gtattttgtt attaaccgat taatcaaaca
    10021 aaaaatgatt accagttcat cgacatacac ataatacctc gataaaaaag gggtgtcaac
    10081 agctttgtaa aatttatttg caacacccct tttttgaggt atactaattt taggaggtgt
    10141 ggtcaatatg ataaaacgtc caccaataaa ttatttagaa cgaaaaaaga tactcggaac
    10201 aaaaataaaa gctataagaa agagtaaaaa attaacacaa ccagcatttg gtcttatgat
    10261 taacaacggt caattaattg acaaaaaaac tatctacgaa tgggagaagg gaacctattt
    10321 accaatacca gagcgattat cccgaattgc tgatttggga aatatgagta tagaggagtt
    10381 agtttgtggc aatgtagaag aatatatttt gggaattatt ctttatagag atagcattgt
    10441 actagatggt ataacatttc cagataaaaa cctgttccag catcttcgtc aacagttccc
    10501 accagtacac tctaatttag atacatggct ggatagatat tccaaattag aaccagagat
    10561 gcaagaattt attgctaaca agacttgtaa taaagttaaa aatgaaaaaa ttagtctttt
    10621 caatatctta aaaatagaag aattattcat caatgctatt gtagaagaat ttgacaataa
    10681 cattcttttc ctcactagca gtatagaaga actactagaa agaatggtag atgaatggct
    10741 acctattcaa ttgaaagaca tgtcttatcc cgaagaagct gtgagagaaa ttactgataa
    10801 tataaacaag ctagaacaaa cgatttcatc aattgggaaa aaatacacta agaaaaaaat
    10861 gaagggaggt gataccatct agtggtaagt actccttgta aactaagagg agatgattta
    10921 atggcaaaaa tatcaaagta caaaaagaaa aacggtcaag tggcgtggat gtataaagga
    10981 cacattgcca ccgatccacg aactggtgaa aaaataaata ctacgagaag aggttttagt
    11041 agcaaacaag aagctcaaaa agattatgac gagtacagac atcaaatatt atacggtgtt
    11101 aaaaagaaag cacctgatat gacatttgaa gacctgtata atgaatggat aactcatcag
    11161 cgtaccagtg ttaaagcttc aacaatcgca atctcagtaa gatacgcaaa taatcaaata
    11221 cttccagcat ttggtaagct taaactatcg aatatctctg tcccatattg tcaaaaagtg
    11281 gtagatgaat ggcacagtaa atatgaaagt tacgattata tgagaaaaca gactgcacaa
    11341 attttacgct acggggttgc aatgcaatat attgacaata atcctatgga aaaaacactt
    11401 cttccacgaa aaaaagagta tgagaaaaat cgtaaatttt actcaaaaga ggagcttaat
    11461 aatttactgg atgcttttaa agattttggt aacatgaaac aatacgcctt cttcagatta
    11521 ttggcataca caggtatgag aaagagtgaa gtactcgctt tacagtggaa agacatagac
    11581 acgtttaata aagaactaca tgtcaataaa actcttgctg tagatgaatt tggtaaagtt
    11641 ataattcaat ctccgaaaac aagagcttct agacgagtta tctctttaga tactgagact
    11701 ctttctatcc tcaacaactg gaaattacag caaaaagaag agtatttaaa acttggatac
    11761 aatactagct ctaaagagca acatgttttt acaacagtta aaaacactct atacattcca
    11821 aacactgtta atgattggtt aagatatatt ttgaaaaaat ataacttgcc tcgtattaca
    11881 cctcatgggt ttagacatac acatgctagt ttattattag aagcaggaga atctgtcaag
    11941 gtagttcaac aacgattagg gcatgaaaat agtaaagtga cattagacat ctatgcacat
    12001 attacaaata atgcacctaa gaaaacaggt caagactttg ctgatatgat ggctcatcag
    12061 taaaagagct ggtcaaaatc tggtcatttc tagtatacag gcaaaacaaa aaagctagaa
    12121 cccttatata tcaagggttc tagctcctat aacaggttta cccaacactg ccttccatct
    12181 cataactgat caatcgattg agttcgactg catattccat tggaagttct ttggtgaatg
    12241 gttcaacaaa gcccatgacg atcatttcag ttgcttcaga ttcggtcagg cctcggctca
    12301 tcagatagta gagttgttct tctgagattt ttgagacttt ggcttcgtgt tctaaagaga
    12361 cttggctgtt gtggatctca ttgaatggga tcgtatcgga tttcgaccat tcgtccatga
    12421 tgatcgtgtc acattcgata tgagagatcg aacccgcact gtttttggca aaggttactt
    12481 gtcctcgata gtttacttct ccgccgtctt ttgaaattga tttagagacg atagagctag
    12541 atgtatttgg tgcattgtgg atcatttttg cacccgtatc ttggatttgg tttgctcctg
    12601 caaaggcgat ggagagcatg gtgcctcgtg caccttttcc atctaagtaa acacttgggt
    12661 atttcatcgt tgtttttgca cctaggtttc cgtcgatcca ttcaacggtt gcgccttcgt
    12721 atgcttttgc tcgtttggtt actaagttgt acacattgtc tgaccagttt tggatcgttg
    12781 tgtaacggca atacgcatct tttcttgtaa agatttctac gatggcggca tgcaggctgt
    12841 tacttgaata agtaggtgcc gtacaacctt cgacatagtg gatgcttgct ccttcgtcaa
    12901 caatgatcag cgtacgttcg aattgccccg tgttttccgc attgatccgg aagtacgttt
    12961 gtaatggaac atcgactttg acgccttttg gcacgtaaat aaaggtccca cctgaccata
    13021 cggctgaatt cagcgctgct aatttgttgt cggttggcgg tacaagtttt gaaaagtact
    13081 ctttgaataa ttcagggtat tctttcaaag cagagtcagt gtcagtaaag acgattccta
    13141 acttttcgaa ttcatctttc atattatggt acacgacttc tgattcatat tgtgcggaag
    13201 caccggctag ataagctcgt tcagcttctg gtataccaat cttttcaaat gtatctttga
    13261 ttttttctgg tacgtcttcc cagtcacgag cgggtttgtc acttggtttt tggtaatatt
    13321 tgatggcatc gaaatcgatg tctgaaaggt cggggcccca tgtttgcatt ggcattttgt
    13381 taaatgtttc tagagatttc agacggaatt caagcatcca ttctggttcg cctttgattc
    13441 ttgacatctc acggatcact tcttctgtca agccttctcc tgtactgaaa accggttcga
    13501 catcatcgtg aaacccgaat ttatattctt ctaattctgg tacgcccatg ttctcactcc
    13561 tcttccttgt ggtaatgatg gaaagctgcg gtaccatcgt tttccattgc ttttcctagt
    13621 gctttccagg caagtgtcgc acatttgatc cgagcgggaa atttagctac accaccaagc
    13681 atagcagcat cgcctaattg gtcgggatct ttgacttctt ttccttggac aagctgtaga
    13741 aagtctacag ttaaatgttc tgcttcttct attgattttc cgatgacggc gtctgtcatc
    13801 atcgaggcac ttgccgtact gatggagcag ccactgccgt caaaggcgat atttttgatg
    13861 attccgtctt ttacatcgac ttgcaattcg atcacatctc cacatgtggg gttgttcaat
    13921 tcgatcttgc ttgtcgagtc agtcaagctt ccacgatgat gcggatggga agaatgatcc
    13981 aagatcactt gacggtataa attgtctaat ttagatagtc ccatgttgga aaaactcctt
    14041 tgttgccatg attgcttcaa ctaaacggtc ggcgtcttgc gttgtgttgt agaaataaaa
    14101 gctcgcgcga gcagtcgctg atacttcaag gtacttcaat agcggttgcg cacaatgatg
    14161 acctgctctg acggctaccc cttccatgtc taaagctgtc gcgacatcat ggggatgtaa
    14221 cccatccaaa ttgaatgcaa cgactcctgt ccgaaaattc gggtcttgtg gaccataaac
    14281 agtcaatcca tcaattgctt gtaattttgg caacacataa gcggctagtt cttcttcata
    14341 tcgatggata ttgtccatac cgagtttttg caaataatcg attgcatggc ctaatgcgat
    14401 agcgccggcg atatttggtg tccctgcttc gaatttccaa ggtagttctt tccatgtact
    14461 gtcgtataat tcgacaaaat cgatcatttc gccaccaaat tcaacaggtt ccatttcttc
    14521 taaccatttt cgtttaccat ataaaacacc aatacctgtt ggtccgcaca ttttgtgtcc
    14581 gctgaaagca aagaaatcac agtctagtgc ttggacatca atggccatgt gcggggcaga
    14641 ttgagcacca tctactacga tgaccccgcc gttttcatgg acaagttcag ctaattcttg
    14701 aacaggattg aagacaccta agacattgga tacatgagca atggagacga ttttggtttt
    14761 gtccgtaatc tttttcgctg catcctccat atccaggaag ccttcttctg ttagttcgat
    14821 atatttcaag acagcacctg ttcgttttgc caactgctgc cacgggataa cattagaatg
    14881 atgttccatg taagagagca ctatctcgtc tcctgctttg atatagcggt cgccgaaggt
    14941 tctggctacc caattcaagc ttgtcgtcgt accacgagta aacagcactt ctgctgtttc
    15001 ttttgcatgg atgaacgccc gtactttttc tcttgcttgt tcataatcat gggtcgcgcg
    15061 ttctgctaac gtatggacac cgcgatgaac attggcgtta tcgtgttcgt aatagtacgc
    15121 taatgcctgg agtacttgtt ttggcttttg ggtcgtcgct gcattatcca gataaactaa
    15181 aggttcatca ttgacgtctt gaaataagat aggaaaatca ttgcgtagct ttttagcatc
    15241 gatcatccat tcaacttccc ttcgattact tcgactaatt ctttccgaac ttgttctaca
    15301 gggattgctg ttaagacaga accgaggaat cctcgaatca ctaagcgctc tgcttcttct
    15361 ttatgcaatc ctctactcat cagatagtac atttcttctg gatcaactcg tcctacactg
    15421 gcagcatgtc cagcagttac ttcgttttca tcgatcaaaa gaataggatt cgcatcacca
    15481 cgtgctttat cagaaagcat caagacacga ctttcttgtt gggcatctgc accttttgcc
    15541 cctttcaaga tgtggccgat accattaaag gtcaatgttc ctttttctcg gatcactccg
    15601 tgttgcaaaa tatgcccgat cgtatgaggg gctttattgg ttactcgtgt atcgattcct
    15661 tggatttgtc tgcccgagct gattgccacg attttgactt ctgcgtgtgc accttctcct
    15721 gctaaatctg agtcaaagtc agcgatcaca tgaccgtcat tcatgacacc aattgcccag
    15781 tcgacagaag catctcgtaa aatgtgccca cggcgattca tataagaagt aatattttct
    15841 cctaattgat ctacggctga atatttgatt tttgaaccag ctttagcgat gacttccacg
    15901 atgatattac ctgatgattt tgctacttgt tctttggttg tctggaaacg ttccagataa
    15961 gaaaattcac tatgttcatc tgccacgatc aacacatgct tgaagaagtg ctcatcggat
    16021 gcgccatctt gaatgaataa ggactcgagt ggttcatcga tcacgacatt tttaggcaca
    16081 tacaggaaaa taccgctgtt cataaaagct acatggagtg cagtcaattg gtcttcgttc
    16141 atgtttactg cttttttcat ataatattct tggactagtt ctggatattc gatcattgca
    16201 gtgaacaagt cggtaaaaat gactcctttt tctgctaatt ccacaggcag ttgttcaaaa
    16261 atcgtccatg aaccttgttg gacaagcaca ggattgtctt tcattgcatc aaatgccgga
    16321 atcgtgcctg tttcactgat ggtttgtgtt tctttcacat caaataacga ccagcgatgg
    16381 aatttcaccc gatcgatatg cggcaatggc agttcatctg ctttcgctag tgcgtcttga
    16441 cggaaggttc tcatccaatc aggttcgcct ttacttaaag aaaaatcatt taccgcgtca
    16501 agataatcga gccagttttt ttctttcatt cttgctcccc cttacgcttc ttcttcttta
    16561 tagtcgattc ctaattcttt actgatacca gcgtagcctt ctgcttccag acgtttagct
    16621 aggtcagcat tccctgtcat gactactcgg ccttccatca tgatgtgaac gacatcaggt
    16681 gtgatatagt tcaataatcg ttgatagtgg gtgatgatca atgcaccgaa attgtctccg
    16741 cgcatttcat ttactccttt agcaacgact ttcaaagcat cgatatccag acctgaatcg
    16801 atttcgtcta aaattgcaaa tgtaggttct aacatcaaca attgcaggat ctcattccgt
    16861 ttcttttctc cgccagaaaa accttcgttc agataacgtt cagccatttc ttctggcata
    16921 tttagtaaag ccattttttc atctaacttt ttcaaaaatg ccataacaga aattttgtcg
    16981 ttttcatcac gtttcgcatt gatcgctgca cgcatgaatt ccgcattcgt gatacctggt
    17041 atctcacttg gatattgcat agctaaaaat aagccaagtc gcgcacgttc atctacttcc
    17101 aagtctaaaa catttttccc gtcaaacaaa atttcgcctt ctgttacttc atagtttgga
    17161 ttgcccatga tagcggcaga taaggtagat tttcctgtgc cgttaggtcc catgatggca
    17221 tggatttctc cggttttcat tgttaggttt acgcctttaa ggatttcttt ttcctcgatc
    17281 gacacatgta gattttttat ttctaagaca gacatgcatt atacccccaa attctctttc
    17341 gttctcactc attttagact aattgagaat gaagcgcaat gaccttcctt actaaaatca
    17401 aatatctttt atttattatt aaacaatttt gatttctaaa ttagaatagg tataaaaaag
    17461 atgagaaata agccattaca gacttatttc tcatcttttt tgttccatac cttattttgc
    17521 atcagccttt actggtttaa cagagccgcc ccatttgtct gtgatccatt cttggacttc
    17581 tttgcggtga agcacttcaa tcagtttttt gattttgtca ctgtcttcat cacctttacg
    17641 agtcgcaata atattcacgt aaggagagtt gtccttttca agcaatacgg catcttctaa
    17701 tggattcaac cctgcgccgt aagcgaagtt tgcgttgatt gcaactaggt caccttcatc
    17761 attttggtac gtagaagcta aaagtgatgg gtcgatcgta tggttgaact tcaagttctt
    17821 agggttttct tcaatatcat cgaatgttgc tgtttccaga tctactccat ctttgacttt
    17881 gactaagcca gcatcttgta gaattgtgat gatgcgtccc cagtctgatt cagaatttga
    17941 agtaatgatt gttgcaccat cttttaattc ggaaacatct ttgacttttt tagagtacaa
    18001 gcccattggt tcgatgtgga cagcaccggc attgacaaag tcatatcctt tttctttgat
    18061 ttctttgttc aaataaggaa tatgctggaa gtaattggca tcaatgtcgc cttcttccaa
    18121 agattggttc ggtaatacat agtcatcgaa tttgacgatt tcaagatcga ttccttcatc
    18181 tttcaataat ggtttcacat gttccaaaat ctctgcgtgc ggtgtcggtg aagcgccgac
    18241 tttcaatgtc gtgtcgtctg ctttatttgc tgaatctttg ctgtcgctgt tgttaccgca
    18301 tgctgctaat cctacagtca gcaaaagcgc tgctgcaaat ccaaaaattt tctttttcat
    18361 atcctacatc cccctatatc ctattatctt ttgtctgttt tcttagttaa gaaatcaccg
    18421 attccttgaa cgataaatac gattagtaaa ataattaaag tcgcaacgaa tgtcactgtt
    18481 agattaccac gctggtagcc ttcctgccaa gcaagacctc caagtccacc tgcgccgatc
    18541 gcgccggcca tcgcagtaaa tccgatcatc gagatcgttg taactgttaa tccagaaatc
    18601 aatgcgggaa tactttcagg tatcaagacc ttccagatga tttcccagta acttgctccc
    18661 attgcatctg ctgcttccag tacaccaggg ctgacttcac gaaaagcaat ctctactaga
    18721 cgggcataaa atggtgctgc ggataaaaca agagctggaa tggctgcttg cgcacctagc
    18781 atagtgccta cgattgcttt agtaaatgga atgatcaaaa ccatcaggat cataaatggc
    18841 gttgaccgga aaatattact gatgatcgat acgattccat aaatgattcg agcatacggt
    18901 ttgtttttgc gtccaataga gtaaaggatc aatcccaaaa ctaatccgat gatcgtcact
    18961 aagaccattg agattaatgt catatatagt gtatcaagga tagcctgatt catcgtttcc
    19021 gggttgattt gtttaaaatc tagatatgtt tctgaaaagc ttttatccac gatggatcac
    19081 ctcaattcct actccttgtt ctttgatgaa cacttctgct tgatctaatt ctttggtttc
    19141 accagtcatc aagacagtca atgaaccaaa ggaaccttct ttcacttgtt tgatctttcc
    19201 atacacaacg ttgacatcga tgttatagcg tcgaatcgct tgggaaatga ctggctcgtt
    19261 ggcatttctt tcgctaaagg tcaaagttgc caaacggccg cttggatttt ctttgatgag
    19321 ttcagctaat agttctgtcg aatcagcttc tggttcgatg tcttgttgta caaagcgttt
    19381 ggttacttct tttttcggtt gtctgaagac agtcaatacg tctccttctt ctacgacttt
    19441 ccccaactcc atcacagcga ctttgttgca gattttgcgg atcacattca tttcatgtgt
    19501 gatcaagacg atggtcaaat tcaatttctt attgatcgct aacaataagt ctaatacttc
    19561 ttctgttgtt tgcgggtcca atgcgctagt agcctcatca caaagcagga tctcaggatc
    19621 atttgccaat gctcgtgcga taccgacgcg ttgtttctgt ccgccggaaa gttgtgaagg
    19681 atatgcttgt ccgcgtcctt ctaacccgac taaacgcaac agttcttctg cccgttcttt
    19741 acgtttgctc tttggtacgc cagctaattc cagcggcagc tggatatttt caagtacagt
    19801 tcttgaccat aacaggttga aatgctggaa gatcataccg attttctttc ggaatgtacg
    19861 taattctttg ttttttaatt ttgtaatatc ttgatcgttt acgatcactt cgccgctcgt
    19921 gggaagctca agtccattca ggagacggac taatgtactt tttcctgcgc cagaatagcc
    19981 gacgattcca taaatatccc ctttttcaac gtttagtgaa acgtcattga cggcttggat
    20041 gtttccgttt ttcccattga atgtcttttt gacattcgtt agttggatta atgacatgcc
    20101 attcacatct ttctcttatg atttttcaaa caaaaaagcc ttcgccctct tgccttaagc
    20161 aaaaggacga aagcttgaac ttccgtgtta ccaccttgat ttaccgttac ttcgcaataa
    20221 cagcctcttc cagtacttgg acttagcttc tttccgtata ctgtcgcgct gtaacgggca
    20281 ctcccgtagt aagtttgctt acgctcgctt actctgctct aagaccatct tccatctcat
    20341 tttcgttacc cattttcagc aaacagggct ctcttcaaac gtccgtgaca tgtactcttc
    20401 ttttcaaagc tttctcgttt catataggat tgcttatgat tatagcaact ggaagaatca
    20461 gtgtcaactt ttttcaagtg attttctgat tttataattc gtcaaattct tttggatcaa
    20521 catctttgaa acttaagatc cacgcattca tttcatctga atcattcaag atattgatat
    20581 cttcaccgat tttatcatta acagaagaaa ctgtacccgt tagcgggctg gcaaattcat
    20641 tgaccgcttt ttccgcttca acttcgatca gaggttcatc tttttttagc gattgtcctg
    20701 cttttggcag attggcaaac gtgatgtctc caagttcttc ttgcgcttca tttgtcaaac
    20761 caacacagta ttcttttcca ttaaataaga tccaaaggtt gtcctttttc ttcaaatgct
    20821 tgcctgccat tttatatcag ttctccttca taaatttttt cattgaatcc aattgcaaca
    20881 agctggtcct ctcgtaagat cagtggtcgc ttgatcagca taccatctgt cgataagact
    20941 tggctcgctt ttgaagccgt aaactcgcct acttgatctt tcagtccaag ttcccgatat
    21001 ttcatcccgc ttgtgttgaa caggcgacgg attggtactt gactcgtttc tagccaagtc
    21061 tcaatcgttg aggccttcgg tacttctttg atcatatcaa cggtttgata actaacgcca
    21121 tgctggtcta accacgcttt ggcttttttg catgttgaac atttcgggta ccagtaaaag
    21181 gtgtacaatt ttcttacctc cttgaagatc ttgcaggtgc ttcattttgg tatctcatcg
    21241 ataatatcaa cccgataccg atcatgttcc ctaaaatcga ggatcctccc tgactaatga
    21301 aaggcaatgg gatccctgtt aaaggaagta atccgatatt tgctccaata ttctcaaaga
    21361 catggaacag cagcatcatg atcaaaccgc ttgcgatata ggcgtaaaat tcattattcg
    21421 tatcgaaaca cacccgaatc atacgataga ttaaaataaa atacaagaaa atgacgaatg
    21481 caccaccgat aaagccgaag ttttcaccga taacggtaaa aatcatatcg gactcacgaa
    21541 caggcacata gatattgctt acgttgaatc ctttaccaaa caagccaccg gtaccaattg
    21601 ccaaaagtcc ttgggccggc tgataactca ttcctgacgt atcatggaaa gggtccagcc
    21661 atgaatcaat acgtgcaaac tgataagatt tgaatccaac tttataaagc aagtctcttc
    21721 cgccttcagt cgtaaccaag aagatcgttc ctgctccaac gactactgcc aagattacta
    21781 caggtgcgat gatgcgccaa gagattccag acatcaggaa aatcccgcca aagatcgcaa
    21841 gaaagacaag catcgttcca aagtcatctt gggccatgat caatgctaaa accggtattg
    21901 tcacgatcaa gagcttccca atcagccaaa agtccgattt catcgtccgt tcttttactt
    21961 gcgtattatg tttagttacg atcagtgcca tcatcaagat gtacgcaatc ttcatcaact
    22021 ctgctggctg gaaagtaaac gcaccgaatc gaaaccagtt tttagaccct gttgaagcag
    22081 ctaaattctg atcatagaat ttgagcaaga gtcccattac cactaacccc aaaccataaa
    22141 ggtaaggagt cagtttccag atccatttgg aattcaaatg catgatgaca acgattgctg
    22201 ccgctccaac taaataccag acaacttgca tccctacgcc tttcaagact gctggattgt
    22261 tcggatcatg gctaagtgct acatataatg agagcagacc aatcaaacat aacagaaaga
    22321 ctggtaaaat cacgccataa tcaatacgat tatcgttcga agcttttaat tttttttcca
    22381 tgtttcatcc cttttcttaa aaaccatact gctgattatt atagcggtcc agttagataa
    22441 tggaaagtct ttccatagac atttgggaaa aattaacttt ccgtttgtgc agttgcttga
    22501 gcaaatgcag tacaaaagcc tactgcttat ctttagtgta tcatagaact ttttttgata
    22561 catgcaatta tctaccagct gagattctcc tcgctgtgag aagtttctgt gctttcattg
    22621 tatcgaagga tctcttcggc aatctctagc agctgatcag aaaccagatt ggttcgttgg
    22681 atgaaataaa aatatcgatg gaaattcaac ggagtcattg gcacattttc tggaacagag
    22741 cgcttagaca aaatcgagcg accgattcct tccttcagca acgcaacaat tacatcgtta
    22801 cttttcacga tcatcttctt atcttggata ttcatctctt caaaataacg ctgcgtgtaa
    22861 tgaaaaacac cagagtttgc ttctcttaca agccacaatt tgctttttgg gtccccagcg
    22921 atgactagct ggtcttccat caaagagtat ctttgtacgc cggaagtctc taatggcttt
    22981 tcgataaaac caaaatcgga ttcatgtttc gctacttgtt ctaatgattc atgagaattc
    23041 gtgatttcga tctcaaaatg cactttagga aaccttttga tcagatgttt catcaactga
    23101 ggcaaaagat agacagcaaa ggtgtgggaa gcaacgatcc gacatacttc ttcttcattt
    23161 tgttcattga gcaatttttg ctgagtttct tcccattctt ctaacaaaac cagtgtccgt
    23221 tcatataata agtcggcttg cttagttgga agcatctctt ttcttccgtt acgttgaaaa
    23281 agatcgatat tcaattcccg ctccaactgt ttgatttgat tcgagactgc tggttgagat
    23341 aaaaacagta cttctgctgc tctggaaaaa tttcttgttt catatactgc tcgaaaagtc
    23401 gttaataact taaacatggc accacttcca taacttttta tgataattac tataaaaact
    23461 atttgattta aatatacaaa aaaccatcta taatagaaat gtacaacaaa acagttgctg
    23521 atccaactag taacttagat gaagacaatc agctgtctgc ttgctcgtaa tcatacattc
    23581 ctattcattt tacaatgtat tcgttcatct tggtactaaa atctattaaa taaaaaggag
    23641 aatattatat atgaagaact ttttgaaaat tattccgatc ccgatctgcg ggttgatcct
    23701 tgggttagct tcccttggaa atctgtttaa agactatcac catgttgctt taggcaatct
    23761 aactggcggt atctctatga ttcttatgat attcattttt gttaaattgt ttatcttatt
    23821 cgaacacacg aaacaaacgt tgcatgatcc aatcatcgcc tccgtttcac caacttttac
    23881 gatgtcactc atggttattt gtacttattt tgtttcatat gaaagtattg caccaattgt
    23941 caaattcatt tggctgtgcg ctgttatctt ccaagtgatc cttgtctttt atttcaatta
    24001 tcaccatgtt atcaaagctg atctttcaat tgaagcaatt tatccaagct ggtttatcat
    24061 ttacgttgga tttggggtca tcactgtaac tgccgggaac ttcttcccac ttattggaaa
    24121 aattttcttt tggatttcat tgatctgcta tgcgttctta ttgccgatca tcatcaaacg
    24181 tgtctttttc gtaagaaata tggctcatcc gacacgtccg ctgattacga tcgttgcagc
    24241 acctggttct ctttgcctaa caggttatct taaaaacttt gctgaaccta atttttatct
    24301 tgtcgtagca ttgttcgctt tatctcaagt attgtatttc gttgtgctgt ctatgcttcc
    24361 acgtttgttc aagcttcgtt tttatccaag ctatgcagcc tttacattcc cgcttgttat
    24421 ctctgcaaca gctatattta ctactgttca ttacttcaac agtttaggta tctatagtag
    24481 cgtattggat ttcttaaaag ttgcggaatg tctgtttgca agtgtagttg tcttctacgt
    24541 tcttgctcat tacgtacgtt tcttaattaa agaacatagc aaacatggaa aatttgtttc
    24601 taaaaaaatc gcttaataat cgattcaata ggttgtgaaa aagctgttct gcatcaagta
    24661 ataagaacgg ccaaacaaaa acagctgttc atgtttttgt actggttggg cttattaccg
    24721 cagatgcaag cttttgaaca ccgtttacca agaggtcgta aaagaagtgg tcagcttcaa
    24781 gaaataagaa ggaatttacg aaaattgctt ctcaaatttt tgtgaaattt cggcttattt
    24841 ccgtagaagc tacttctgga acaccgttta ttcgaaacaa gaggtcgtac aagacttttg
    24901 tcacgacctc ttgttctttt gtcaaaatac tggtttagtg ctactatgtt cgagtatgct
    24961 tttagtattt attgacgaaa ggaaccgatc aaatgaaatc attgtcacat ccaataaaat
    25021 ctgtaaagga ttcagcggtc cgcgaaatct tacccggttt actgctttct tttgccatcg
    25081 ctgccttcag caggcttctt gctatttatc tgccacagtt aggtggagcg actattgcta
    25141 ttttattggg tattttatta ggaaatactt tttttaaaca gcctgttcta gcaatcggca
    25201 caaaatttgc tgaaagcaaa ctattagaat tctctgtttt tttactaggt gcaactgtca
    25261 cagctcaaac gattgctcaa attggtgtaa aaggaattgt ttttgtgtta ctgcaaatgt
    25321 cagtcactat catcggtgct tacttgattg gtaaaaaact gcaattcagc gatacttctt
    25381 ctttgatgat ggctggagga aacgctgttt gtggttcttc tgctattgct tcaatcgccc
    25441 cttccatcca tgcgaaagag gaagaaaaag gacagatcat cacactagtc aatctactgg
    25501 gtactgtgat gatgttgact ctcccttttc ttggattaca gttgtttggt ggaaatctca
    25561 ttgaaaaaag tgcacttttg ggtggtacac tccaatctgt tggtcaagta gtcgctgggg
    25621 caagcttact tgacaattct gttgtcgaat tcgccatgct atttaagatt ctacgtatta
    25681 tgatgctcgt tgttgttgtc tatctgtttg aaaaattcat gcacaagaaa caaccagctc
    25741 tgtttgaaac gccaactgat acgcagaaaa aacgaaaatt accgcttcct tggtatgtat
    25801 tagggtttgt gatcttttgt ttggtcaaca gcttgttttc tttacctgta gttattgacc
    25861 aatcggcaca ttttatcagc agctggtttg agatcactgc tttagcggca attggtctgc
    25921 gtttagactt tgcaaaattc atgaaagaag gtacacgctt cttatcttat ggattagctg
    25981 tcgggcttct ccaaacagtg atggctttac tatttatttg gctgatcaaa gtttagaatg
    26041 aacatgaaaa aacagttgtg attctcgcat ggaacaatgt ccgaatcaca actgttttta
    26101 attttgcaga tatccttcta acaacaacaa ttggcgtttg atttcaaccc catctattgc
    26161 gtttcccata tatcctgtca gttttccatt ttgcccgatc actcgatgac aaggaataac
    26221 gattggcaat ggattggttc gatttgcctg cccaatcgct cgcacagctt tcggactatc
    26281 aacagcaacg gctacttctt tatacgttcg gatttctcca taaggaatgg tcgacaaagc
    26341 tttccagaca ttttgctgaa aaggcgtacc tctctttata gataaaggaa catcaaattc
    26401 ttttcttttt cccgcaaaat attcttcaaa ctgttcttgt gtgcgcgtta aaattcgctg
    26461 attcgctgat tcgctttctg aaattggctg aaaagataca gcagtcaatc cggattcatc
    26521 tgcatctaac cataaaaagc cgataggtgt gtgtattttc attttgtttg ctcctagtca
    26581 atagactgga acttcctcct ttttctctat ccaaaactac ttgccaacta ataaaaaatg
    26641 ttcttaaaag tttgataaac cgaggaaaca tggtaaacta aatacgttag tttacaaaaa
    26701 gaatacctgt tcttttacgt aaaatcaaat tttaaaggtg ttatttaagg tttattaaat
    26761 tttgaatgta aaccatatat aaacatacga ttgaaaggat agaaacgatg aaagtatcaa
    26821 ttgttgtccc atgttttaat gaagaaaaaa ctgttcctct tttttttgat gaggttgaaa
    26881 aattcaaagg tgcccatgag ttcgaatatt tgtttattga cgacggatca aaagacggta
    26941 cgttagcagc aatcaagaag ctagcctcag cttatcctta tgtccgcttt gtctcatttt
    27001 ccagaaattt tgggaaagaa gcggctctgt acgctggatt gcaagcttct acaggagatt
    27061 tagtgaccgt gatggatgtt gatctgcaag atccgcccga actgcttcct gagatgatca
    27121 accggatcac tacttctgat atcgattgtg tcggcacccg gcgttcgact cgtgaaggcg
    27181 agcctgcgat acgcagtttc tttgcgaaaa aattctacca gttgatcaat aaaatcagcg
    27241 atacagaaat ggtcgatggc gctcgtgatt tccgcttgat gactcgtcaa atggtggatg
    27301 ccgtcctaga attaacagaa tacaaccgat tttcaaaagg attatttagc tgggtcggat
    27361 ttaaaacaga atatatttct tatgaaaacc gcgaacgtgt ggctggcgaa acatcttggt
    27421 ccttctggaa attattcaac tactcgattg atggtatcgt gaacttctcg gatgcaccgt
    27481 taacgattgc ttcatttatc ggcgctttgt cttgtgtcgg ttctggtatt gcaattttgt
    27541 tcattatttt gcgggcattg ttgtttggtg atcctacatc aggatggcct tccatggtct
    27601 cgatcttcct gttcattggt ggaatccaat tgttatgtct tggaatcatc gggaaatata
    27661 ttgggaaaat cttcttagaa acgaaacagc gtcctgttta tatcataaga gaaacagaaa
    27721 aagtgaagcc aaatgaattg aagcctcacc aataatatac gtcaaatgaa gtaaacattt
    27781 ttttaaatga aaaaggactg tgacaaaagt cttgtcacag tccttttttc cgaataaatg
    27841 gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt tgagaagcaa
    27901 ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctatcacaac ctctttcata
    27961 tcttattact tcttcattgc tgcttttagt gctgctgcta atgggctttc ttctggttct
    28021 tctgcttgtg catatttttt cagcaagcgt cgttcttcat gtttggtcat tttcttcttc
    28081 tgctcttttt tatcaagcaa tttttctgtc gttccatcgt atttacaacg gaaataagca
    28141 ccgtttttac cttcgatgat ttccattttc cggtgacatt gcgggcatcg atgattagag
    28201 acttttggat cttttcttct gcggtagttg caatctgaat tggtgcagac atagattttg
    28261 ccgtcacgtg tgtttttctc gcgcagattg gccccacatt ctgggcattt cttttgggta
    28321 atcgagaaat cttgatattc ttgtttgctt gatttgatct cattcaccaa gcgttttgtt
    28381 tctttttcga ttccattcaa gaaggttcct gcttgtttct ttcctgcagc aatagcttca
    28441 aggtcttttt cccagctttc tgtcaaatct ggtgttacta aagagggatt taccaatact
    28501 aataattgct tacctttagg agatacttgc agtccttgag gggtacgttc catcagttca
    28561 gatttgatta gtttctcgat aatctctgca cgcgtagctg gggttcccag actgtatttt
    28621 tccatttgac caagcaagct tgcttctgac aatggtttag gcggtgcaga tagttctttt
    28681 ttgatggcga aatcgggatt gattctcatt cctttttccc atttgactgt ttccgtctca
    28741 gtttcagttt cgcctttcca tcctgcttgg acgacacgat tttgccgaaa aatgaatcgt
    28801 tctttaccaa attcaaccgt aacttttgtt tggctgactt tatggggttg agcaaacagt
    28861 cctaaaaaac gagagacaat catttgatag atttttcgct cttcattact taatttttca
    28921 taacgtgctc tgttttcagt tggcaaaagt gcatggtgat cggtcacttt actgtcttgg
    28981 aatacttttg tctgttggac gatggctccg tttttcaaat actgcttgac ctcaggagca
    29041 aagtcgctga ctgcttgcaa tcgttctttc atcgtacttt tcatgtcatt tgtcagatat
    29101 ttgctgtctg tacgcggata agtaacgatc ttatgggtct catacaaact ttgtacaaga
    29161 cttaatgttt tctttgcaga atagccatag cgttgattgg cttctctttg gatctctgtt
    29221 aaatcataag gcaatggcgc agattccgtt tttaattttt cttggacttc tgtgacagtt
    29281 cctttgcttg tactgatcaa ttgaacaagt ttttgtgctt cttcttgtgt ttttaaagca
    29341 aattgatttt tttgaagcat tttggcttgt tcttttccag cttgcaacgt gatcgtgaaa
    29401 tacgtttgtg gacggaactg ctcgattttc ttttcttggt ctctcactaa tgctagtgtc
    29461 ggtgtctgca cacggcctgc tgataaatta tccgcgtact tcacagttaa ggctctggtc
    29521 acattcaatc ctaccagcca gtccgctttt gcccgggcaa gagcagattc atacaatgca
    29581 tcatattctt tcgcaggtct tagttgcttg aatccagttt tgattgcttt atctgtttga
    29641 gaagagatcc ataaccgctt cactggttta ttgaaatgca catactctaa gatccagcga
    29701 gcaacaagtt ccccttctct tccggcatct gtcgcaatga ctgcttctga gacatctttt
    29761 cgctgagcca gctgcttgat tgcttttaat tgatgtcctg ttttaggaag tggtttgatt
    29821 cctagttttt tagggatcat tggcaacgtg tccatttgcc agctctgcca ttccttattc
    29881 agatcttccg gcattttcaa tcctaataaa tgaccaaggg cccaagtaac gatcaccttg
    29941 ggtccttcat aataattttt gtgcttttga ttagcaccaa gcaccttgct taggtctttc
    30001 gcaacgcttg gtttttccgc tagaattagt tgtttcataa aattcctttc tgctttctac
    30061 tgtgatgggc tgatgatttt tcaacaacgc aagtcccttg tattgctgta aatcatcgtc
    30121 acactcttca caccagcgct catctccgtc attccaaaag gcgctgagaa agttactttt
    30181 tgcattgata tattcataat tttgatggat ttcgttccat tgtttttcgt acgcttgtcg
    30241 tgcttcttcg aaagactcga atgtttcttc ttcttcaata tcttcttccc agtcttcaaa
    30301 aaaccaccaa ggctcattgt ccccgaacat ggtaattact tgatacatac tcgtgctcct
    30361 tctttcagct tttctagact catcttagtc acttttcaag aaagttgcaa gaattttctc
    30421 ttataaaagg gtcatttaat gaacatctta aaattgttac aaatgaatct gattgtttaa
    30481 ggcaaagtag cgataaagtt attgatcatc caaaaatagc tgtcttctgg atcgattgtt
    30541 ggttcttttg taaagtatcc taaaaaacgt aaggaaagat aaccgtggat catactacga
    30601 agttccctgc ttcgatgaac tttttcttct ttcgttaatt gaaaagcctc aaatatctgc
    30661 aaaatgatct gattcgtttc atggattcca tctaataaaa cagcttcatt ggtatgcggt
    30721 acactgatca gtaactcata cactgcttga tttgaaaaag caaaggatcg ataagtttct
    30781 gcatagatct gcagtgcttc ctgaccactt tttcccacaa gagcccgtcg cagctggtca
    30841 ttaagttcct gcagaagttt cgctgttagc gctgttttga catcacgaat atttttgaaa
    30901 tggttataca gcgagggagc cttgatatcc aagcgtttgg ctaaatgctg aaaggttatt
    30961 tgctgaacat ccatctcttc tgctagttct cgaaagcagt cgatgatttt ctcttgagac
    31021 agatttcttt ttttcatttc catgtttcct ctcataaaat aaatccttca ctctttcagt
    31081 ttaccacgaa aaagaaagag aaaaaagaga ctttcattga taaactacat attgtagttt
    31141 ataataaaga gctgtagatg aaaattttca gaaagaagga gtctaattgg ctgcaagaat
    31201 aaaggaaaaa ttatttagga aaagagaaac ttgggaacaa aacttgtttg tcttatggtt
    31261 tggaacattt atggctggta tcggatttag tttagtcatg ccttttatgt cactttacat
    31321 agatacgtta ggtaattata gtacgtcaca attgaacttt tggagcggat tgactttttc
    31381 atctactttc ttggtgacta cgcttatctc tccttggtgg ggaaaattag ccgaccaaaa
    31441 aggaagaaaa ttgatgctgt tgcgtgcttc attaggaatg gcaatcgtca tttctttgat
    31501 gggttgcgtg actagtgtgt atcaattagt cgcattgcgt ctgcttcaag ggattttttc
    31561 tggttatatc agtaatgcca ctgcccttgt cgcaactggg acgccaaaag aaaaaagtgg
    31621 tcaagttctt ggaaccttag caactggttc tgttacagga acattacttg gaccgcttct
    31681 tggcgggatc tctgcttcag cgtttggcta tcgccctacc tttttcatta cagggatcat
    31741 cttatttttc gtcttcttgt tgagtctgtt tttcgtccat gaaaaatttg tcccagtgaa
    31801 aaaagaaaac atggtttctg ccaaacagat tttcaaagac ttgaaatatc cacacgtcgt
    31861 catcggtatg ttcgtcacaa cgatgatcat ccaagcatcc aacaattcca ttagtccaat
    31921 catcagtctg tacattcgcc aattgctgca tggacatggg aatgttacgt tgatcagcgg
    31981 aatcattgct tcgatacctg ggattgccac tttgatagcc gctccaagat ttggtcgctt
    32041 aggtgacaag attgggagtg aaagaatact tgcgattggt ttgggttttg cgattctggt
    32101 ttatatccca atggcattcg tcacgaatgt ttggcaatta gctgccttac gttttttgat
    32161 tggtatctct gatgcttgtc tgctccctgc tgtccaagca ttgatcacaa aatattcgcc
    32221 tcatcaagct gctggacgga tcttcagtta taaccaatct ttccaagcaa ctggtaacgt
    32281 agtagggcct atgatcggct ccagtgtttc cagtgcattt ggttatcgtg gcgtctttct
    32341 ttcgacttct cttcttgttt tggtcaactt cttgcttgta cgacacaata cacaagagat
    32401 ccatcagcaa gaaactgcag aagaaaaagc ttcaggagtc tccatagctt cagggcactc
    32461 tccttctcat agacaataag cgtaaatgaa aaacactgct tgaacagttg tcacagactg
    32521 tccttgcagt gtttttgttt aggcctgttt tttcaagaac tcagataaga ggaataatcc
    32581 cttttccaag gtttcttttt tacaacagta acctagtcgg gcatgcttcg gtaaatcaaa
    32641 ggcacttcct ggtactaata gtactcctgt ttcttctaat aaattgatac aaaatgtctg
    32701 gtcatcttct tcgatggcta atttaatgaa agaagtagag acgtaattgg gagcgacaag
    32761 ttcaactttc ggttcattgg ctacccattg ttttaaaatc acaaggttct ctgtaatgat
    32821 ctttttgttt cgcgccaata ttttttcttt attcttcaat gcatgtacag caagatcatc
    32881 tgacaggact ccgccgcaaa tcatcgtgta gtctcgatac tttcgaaaaa cttctgccaa
    32941 ctcaggtcca gtagctgtcc agccaatacg aatacctgga atggagtagg ttttggatag
    33001 ggaattggtt gctatacctt tttcatagac atctacgatc gacaagaatt cacctttatc
    33061 cgttaaaggc gcatatactt catctatcaa tacatatgca tctactgtac gagcaatttc
    33121 tgcgattttt tctaaagttt tccgatctag caatgtgcct gtaggattgt ttgcactatt
    33181 caaacagatg atttttgttt caggtttgac taaggcttct agctgttcta aatcaaactg
    33241 ccaatcttct tcttccttca aatgaacaaa gtcaacagcg gcacctaaag atttggggat
    33301 gtcatataat tgctgataag taggaagcat cgaaacaaca tggtctcctg cttccactaa
    33361 cgcgtataga gctaaaagat tagcaccagt cgctccattc gtttgtaaga tgttttccgg
    33421 atcgacggtt tgataaagag aagcgacttc ttgtttgaaa acatctgatc cttcgatcca
    33481 gccatagtcc aatggttcgt ttttgcgttt ttcgaaaaat ttacttacgc tagtcccatc
    33541 taagccaacg agttcgtcta atgtcaatgc ttcgatcgag ctttgtgcaa tatcatatac
    33601 cgctttcttt tcccatttat ttagccattc ttctacaccg aaatttgcga ttttcatgtt
    33661 tctttccccc ttatatcttg atccagccta cagcaagcaa cccgattgaa agcagtgcgg
    33721 ccacacaaat cagcccaatc attacttttt cttttcccgt aatttgatgt ttggtttcac
    33781 gacaagcgat ccagtagaag caaaaaccag gaagataggc aatactacat aaaaggacat
    33841 aagaaaatcc tgctaaaatg atgcccatca attcaaaaac tacagcaatc ccaccgatca
    33901 ctacttgttt tttgattcct tcttttaaag aaaactggac ttgatagatc ccgacaagta
    33961 gataacaaat caaaattgcc gctgtacata aagaataggc aaattgatag gcataatcag
    34021 taactaagaa agtcaataag aatagattag tcaagattgc agtaacaact aacgaataag
    34081 ttggggcatt ttttttattc gtttttcccc aacctttcgg caacagaccg tctcgagcca
    34141 tcaacatcgt tgtttctgct gggagcatcg tccaagacaa ccaagaacca atgatcgaaa
    34201 taatcaagcc gatattgatc agcgctgctc cccaatttcc cacgattcct tttaaaatat
    34261 ttgccatagc aggttgtgaa atagttgcta actcttcttg agataagacg ccgtatggca
    34321 agatcgaagc aaggatatag ataaacaata aacaaagcag accaatgatc gatgcttgct
    34381 gggcttctga acgtttcttc gcgcggttgg ctaaaacact tgcgccttcg atccctacaa
    34441 agacccacat cataaccatc aaacaacctt taatctgcaa ccagatcgtt ccttgctgcc
    34501 ctgttccatt cactagatta tcagatacgt taccccaaaa atcagcagtg aatatattca
    34561 ctttaaatgc gataaataca aatattaaaa ataggaataa tggcactaat ttacagatcg
    34621 tcacgattgt attgatgacg ctcgctcctt caactccatt gtttactaat aaagtcagac
    34681 cccaaataaa aatacttgca aataaaatag aaggaacatt ttgtccacct ttgaatatcg
    34741 ggaaaaattc tcccatggcg ctcatcagca tcgttgcaaa agcaacattt cccagccacg
    34801 cagacaacca gtaaccccaa ccactgatga agccacctaa tttaccaaat gaagcttccg
    34861 cgtaaccgaa aataccacca tctagatctg gacgcttttc tcctaaatga ttcagcgata
    34921 ataccaaagc taaaatacca atcccaacga ttatccatga aaggatcgct ggccctggag
    34981 ctgcagaact agccagatca cttgtgatcc caaacacacc gcttccgatt gacgaactga
    35041 caaccagagc aaccagtccc catttgctaa tacccgtcga tttcttttcc atttccatca
    35101 ccctcactta taaaattgaa caaatcactt gcaaaagatt cccttctatt ttgcaactgc
    35161 tcttgcttaa caaaaagcaa ctttattcat attattggat attatgaact ttttacacaa
    35221 gtatttcaag tataaaatga ataaaaatta attttattgc aaaaaaacag ctatgctatc
    35281 caaaagaaaa ggtgtttctt ttgttagcca tagctgtttt gattcattta atatcgctta
    35341 aacgtattgt aaaacttttg tttcttgata tgcgtggtcg atcaaaccac cacccagaca
    35401 ttccattcca tcataaaata caactgcttg tccaggagtg attgcacgta caggttcgtc
    35461 gaatacgact tctgcacgat tatcatccaa taagcgaact gtcacaggaa cgtcttgctg
    35521 acgataacgg aatttcgctg tacacttgaa ttcttttggc attggttcat tcgtcgtaaa
    35581 gtggatttca cttgcatcca agcttgtggc atacaatgca ggatgatgga acccttgccc
    35641 cacatataat gtgtttgtcg ctagatcttt tcctacaaca aaccagggtt cttgcgaatc
    35701 tcctccgcca ccgatcccta gtccttgacg ttgaccaatc gtataataca tcaagccagc
    35761 atgttgtcct ttgacttcac catcaagagt gaccatattt cctttttttg ctggcagata
    35821 gttgctcaaa aattgtttga agttcttttc accaataaag cagattcccg ttgaatcttt
    35881 tttcttagca gtcgcaaggc ctgcgcgttc agcaattgcc cgtacttctg atttttccat
    35941 gccgcctaga gggaacatcg tttttgaaag ctgttcttgt gataattggc taaggaagta
    36001 agtttgatct ttattattgt ctactccacg aagcatgtgg accacgccgt tttcatcgcg
    36061 agtgacttgc gcataatgtc cagtagctac ataatcggcg ccaagatcca ttgcataatc
    36121 caagaatgct ttgaatttga tttctttgtt gcacatcacg tctgggttag gtgtacgtcc
    36181 tgcgcggtat tcggctagga aatattcaaa tacacgatcc caatattctt tttcaaaatt
    36241 cacagagtaa taaggaatcc cgatttgagc agctactttc gctacatcct tataatcttc
    36301 cgtggccgtg catacaccgt tttcgtccgt gtcatcccaa tttttcatga atattccgat
    36361 cacgtcgtat ccttgttcct ttaacaaaag tgctgttaca gatgagtcga caccgccgct
    36421 catccctacg acaacgcgtg ttttgctgtt gtctgtcatg atatcaccat catttcaatt
    36481 agattctgaa acatctacga gttgaaggtc gcaacttttc agtattttac attatacgtc
    36541 atatttctga aaatttcatc ccttaattat caagtcgtaa aaatactgtt ctactggacc
    36601 tattcagtac acaaacatga tagtcaacca aaaaatcact catcttttga gcattcgata
    36661 taaaaaattg gcatactcat aaaaagggcc agcctttcgg caataaggaa taattttata
    36721 aattgtgaaa aactattttt caaaattgct tcttatcgct taaagctgca cgtctcattt
    36781 acaacctttt ctttttagat gttatgagtt gctcagataa gtgattttgt ttactctaag
    36841 aaaaaaggga ggcaaaagat acatgaatta ctttatcagt gatatgcact ttttccatga
    36901 acgcttatta ggaaaaaacg actttgctcc gcggctcttt gcaaatgtgg atgaaatgaa
    36961 ccaacagttg atcactagct ggaatgcagt aataaaagaa accgaccatg tttatcatct
    37021 aggcgacctt gctatgcatc cgcaatatga aaaagcaaat gcagaaattt tggaactggt
    37081 cactcaactg caaggaacaa tccacttgat caaagggaac catgacagtc gcgctttttt
    37141 ccgttattta gaaaaaaatg atcctaggct tactgacgga agtcccaaat tttattttta
    37201 tgatgtaggt gccatcgtta aattcgacca tcaacaatat tacttgactc attatccgat
    37261 gttgctcggg cctaacgaca ctatccgcaa tcttcatgga catatccatc attacagcgt
    37321 acctatcgag aacgatgtca atgtaggcgt agacgcaccg gaaagagaac tcttaaagga
    37381 aaaactacca tttggcactc cgttatctga gcaacaaatc aaagaaatct atgaagcaaa
    37441 gaggaagtac gataggtcgt gaaaaaactg ccctatatca agtattaaac aaataaagat
    37501 aattactcat atttttcatt tgagtaggct tattgccaca ggaacattag gatcagaaat
    37561 ggagttgtaa caagacttct gtcacaactc cattccatac tattcgtctt tttgctcatg
    37621 gtgttctttt accagttttt tctgtaattc tttatcataa tttcgggcag ctgacgttaa
    37681 aaataaaacg attccgcata ataaaatccc gattccggaa aacaagaaca ttttttctac
    37741 ccctaaacga tcagctaatg gtcctgcaaa taataatcca attggacctg tcaggttcat
    37801 caaagagttg aagttcccta agacacgacc taaaacattc gattcataac tctgctggat
    37861 cattgccatc agcagtgtat tgaaatatgg cgttgcacaa cctgctcctg cattcaagat
    37921 aagaaagtac aagaaccctt gactatcgtt tggaaccaat ccgcttgcac cgatcgtcag
    37981 gcccataatg atgtaggcta taataatagg tttcattcgg tctttccatg ttcctataaa
    38041 actgatcagt gcaccgccta agagcattcc gactgcgtag actacttcca ctgctcccgc
    38101 ctgtccaacg gaaccaccaa agtaatctag cgtcatcaat ggatacagac tgattgctgg
    38161 catgaacaac agcatcacaa atgcaccatt gatcgttatg taccataacc ctttattatc
    38221 catcaattgc tgcagcccaa attttgcatc tttaaaaata gtaagcggaa cttccaatat
    38281 ttcaggagaa acttttggga tcttcacaaa aatcaataag ccgacaccaa aaactgcccc
    38341 caatacatct aataaaataa ggtaattgac aggaacgact gaaaacaaag ccgcacctag
    38401 agctggcgca atgatgaaat tcgctgattg gaccattcct aactgtccat tcgtccttgt
    38461 tatgtgagaa gatggaacga ttgtcggcat aatcgactgg atcgttggca tttggaatgt
    38521 ttgtgcgacc gaacgcataa acaaagacac aaaaactagc caaatcggga aggattctga
    38581 aatcgttccg actactgcta aaataagcgc gaaaatcgct acaataatat ccgtgacaat
    38641 caaaagagct tttttatccc agcgatccac tagcggtcct acaaatgggc ttagtaaaac
    38701 catgggaatc attcctagta aagtagcaaa actcaaaatt gtcgccgaac cggtttctct
    38761 tgtcaaatac cagatgatcg catattggac gaccatacta gtgattcctg acaaaaactg
    38821 tcccgataaa aagaacaaat aatttctctt ccaattcgtt aaaacgaccg actgttcatt
    38881 ttccataaac atccctcttt tctttttcat tttgtatagc gtttgcacaa caatcattat
    38941 acgggattct tttttcaaaa aatacctttt tccctaaata acaatcgttt caatttaaat
    39001 ttctttactt agaaacaata aatcagcaaa atattaaaaa taacaacatg tgttaaattt
    39061 aaaaataaaa aagacaacta atttgcgtcg tccttacaaa gttagtcatc taacaatagg
    39121 ccgtttcaaa actagttgtc tttttatatc cacagatcat tcgacttttt cgaataaccc
    39181 acggctaatc atcccatcca tcagaaaata aaatttatct tggctcattt tctgttttgg
    39241 atctttgaaa atattgactg ctttcaatcc atttgctgta gtgatcgaca ttttcaatgt
    39301 ttgaatatct tttgatacag tgatttttaa tttgaatcct tctttgcttt gcggcgtggc
    39361 atctaatggt cggatcaatt gataattgcc tccgtttgtt tctgtaaatc cattatcgcg
    39421 caatgtatat ctttttgcat caggatgcaa acgatagcta attggtgcgc ccagtaccgt
    39481 tgctgttgtt tcaaatgcca tgattttcac ctcgataaaa ttagtttctc tttattataa
    39541 aagtttatcc tgatttttac taggtttttc agttaagttc cctaaaaaat gaaggcgttc
    39601 tctcagacat ctgttcatat aagaatgact tcactagtta ttttttgaca gcacgaacta
    39661 attgatcaag gaaatactgg atgtcgtctt cggtatttcc caaaccaaag ctgatacgga
    39721 tggattcttt tagtatcggt gtatcttctc catacattgc ttccaatacg tgtgaaggct
    39781 cgatatttcc tgctgtacaa gctgaaccag tagaaatagc gaccccatta agatcaagct
    39841 tcatcagtag caaatcattt gcttcgccaa ttaagcgaag attcaacaca tgagggagtt
    39901 tattcgttaa atcaccattt acttgataag ggatttcgtt tgcttctaat gtatcaagaa
    39961 tcaattgctg gaatccttta tatttgttgt tacgtgcttc acgttcttca ggtgacagca
    40021 gttcaactgc ttttgccata ccccagatcc ctgctaaatt ttctgtacct gcacgccgct
    40081 tttcttcctg ctccccgcct aaaagcaatg cagggatatt tactccgtct cgtttatata
    40141 agaaaccgac gccttttggc ccattgattt tatgagcaga gatacttaat aaatcgattc
    40201 ctaattcttc tggatggatc gtttggtttc cgtacgcttg taccgcatct gtatggaaat
    40261 aagctggatg atccgctaaa agttcaccga tttctttgat tggcatcaaa tttccgattt
    40321 cattgttccc gtacatcaca gagaccaaga tcgtatcttc tcgtaacgct tttttgacct
    40381 cttcgatcga cagattccct ttttcatcta caggcagata tgtaacgtca aacccctttg
    40441 tctctaaata tttcatggta ttaagaacag caggatgttc gatagctgta gtgattagat
    40501 gtctgccttc tttttgacgc gagaacgctg tttctaagat agctgtatta tccccttctg
    40561 ttcccccact gttaaagatg atctcgtgag gttttgcttg cagactgtct gcaatgattt
    40621 gtcttgctgt ttccaatttt tcatgcgcgt ggcgaccaaa tccatgtatg cttgaaggat
    40681 ttccaaacgt gtcttgcatg attgccgtca tcgcttcaat tacttgtgga tgcatggggg
    40741 tagttgccgc atgatccaga taaatagttt tcacttcatt catcccttcc aaattattgc
    40801 taggcacatt ctagcataaa atagcgaaca aaccaaagaa gagctcattt ttgtctagag
    40861 gacgtttcat gggcatagaa aaaaggagct gtgacaaaag tcttgtcgca gctccttgaa
    40921 gctgctcact tctgtcacaa cttcttt
//
LOCUS       DACGDM010000016        40848 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.016, whole genome shotgun sequence.
ACCESSION   DACGDM010000016 DACGDM010000000
VERSION     DACGDM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.016"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..1272)
                     /locus_tag="IXR05_000945"
     CDS             complement(<1..1272)
                     /locus_tag="IXR05_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259483.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKG"
     gene            complement(1274..1942)
                     /locus_tag="IXR05_000946"
     CDS             complement(1274..1942)
                     /locus_tag="IXR05_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAQ4259484.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(2072..2656)
                     /locus_tag="IXR05_000947"
     CDS             complement(2072..2656)
                     /locus_tag="IXR05_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4259485.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(2987..3220)
                     /locus_tag="IXR05_000948"
     CDS             complement(2987..3220)
                     /locus_tag="IXR05_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAQ4259486.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(3235..4185)
                     /locus_tag="IXR05_000949"
     CDS             complement(3235..4185)
                     /locus_tag="IXR05_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259487.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(4182..5024)
                     /locus_tag="IXR05_000950"
     CDS             complement(4182..5024)
                     /locus_tag="IXR05_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4259488.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(5026..5745)
                     /locus_tag="IXR05_000951"
     CDS             complement(5026..5745)
                     /locus_tag="IXR05_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259489.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            6437..6595
                     /locus_tag="IXR05_000952"
     CDS             6437..6595
                     /locus_tag="IXR05_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4259490.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            6667..7893
                     /locus_tag="IXR05_000953"
     CDS             6667..7893
                     /locus_tag="IXR05_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4259491.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(7981..8373)
                     /gene="rpsI"
                     /locus_tag="IXR05_000954"
     CDS             complement(7981..8373)
                     /gene="rpsI"
                     /locus_tag="IXR05_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4259492.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(8389..8832)
                     /gene="rplM"
                     /locus_tag="IXR05_000955"
     CDS             complement(8389..8832)
                     /gene="rplM"
                     /locus_tag="IXR05_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAQ4259493.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(9351..9818)
                     /locus_tag="IXR05_000956"
     CDS             complement(9351..9818)
                     /locus_tag="IXR05_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAQ4259494.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(9938..11476)
                     /locus_tag="IXR05_000957"
     CDS             complement(9938..11476)
                     /locus_tag="IXR05_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAQ4259495.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            11556..12242
                     /locus_tag="IXR05_000958"
     CDS             11556..12242
                     /locus_tag="IXR05_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAQ4259496.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(12443..12970)
                     /gene="msrA"
                     /locus_tag="IXR05_000959"
     CDS             complement(12443..12970)
                     /gene="msrA"
                     /locus_tag="IXR05_000959"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4259497.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(13054..13731)
                     /gene="pgmB"
                     /locus_tag="IXR05_000960"
     CDS             complement(13054..13731)
                     /gene="pgmB"
                     /locus_tag="IXR05_000960"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4259498.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(13728..14858)
                     /locus_tag="IXR05_000961"
     CDS             complement(13728..14858)
                     /locus_tag="IXR05_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4259499.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(14858..17041)
                     /locus_tag="IXR05_000962"
     CDS             complement(14858..17041)
                     /locus_tag="IXR05_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4259500.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(17038..18063)
                     /locus_tag="IXR05_000963"
     CDS             complement(17038..18063)
                     /locus_tag="IXR05_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4259501.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(18108..18935)
                     /locus_tag="IXR05_000964"
     CDS             complement(18108..18935)
                     /locus_tag="IXR05_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4259502.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(18932..19999)
                     /locus_tag="IXR05_000965"
     CDS             complement(18932..19999)
                     /locus_tag="IXR05_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAQ4259503.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(20025..20861)
                     /locus_tag="IXR05_000966"
     CDS             complement(20025..20861)
                     /locus_tag="IXR05_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4259504.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(20858..21727)
                     /locus_tag="IXR05_000967"
     CDS             complement(20858..21727)
                     /locus_tag="IXR05_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4259505.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(21797..23080)
                     /locus_tag="IXR05_000968"
     CDS             complement(21797..23080)
                     /locus_tag="IXR05_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259506.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(23094..24779)
                     /locus_tag="IXR05_000969"
     CDS             complement(23094..24779)
                     /locus_tag="IXR05_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAQ4259507.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            25054..26079
                     /locus_tag="IXR05_000970"
     CDS             25054..26079
                     /locus_tag="IXR05_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4259508.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(26674..30327)
                     /gene="rpoC"
                     /locus_tag="IXR05_000971"
     CDS             complement(26674..30327)
                     /gene="rpoC"
                     /locus_tag="IXR05_000971"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAQ4259509.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(30406..34023)
                     /gene="rpoB"
                     /locus_tag="IXR05_000972"
     CDS             complement(30406..34023)
                     /gene="rpoB"
                     /locus_tag="IXR05_000972"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4259510.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            34751..35719
                     /locus_tag="IXR05_000973"
     CDS             34751..35719
                     /locus_tag="IXR05_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259511.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            35737..36642
                     /locus_tag="IXR05_000974"
     CDS             35737..36642
                     /locus_tag="IXR05_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259512.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            36639..37445
                     /locus_tag="IXR05_000975"
     CDS             36639..37445
                     /locus_tag="IXR05_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4259513.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            37602..38570
                     /locus_tag="IXR05_000976"
     CDS             37602..38570
                     /locus_tag="IXR05_000976"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAQ4259514.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(38887..39411)
                     /locus_tag="IXR05_000977"
     CDS             complement(38887..39411)
                     /locus_tag="IXR05_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAQ4259515.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            39698..>40848
                     /gene="scm"
                     /locus_tag="IXR05_000978"
     CDS             39698..>40848
                     /gene="scm"
                     /locus_tag="IXR05_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4259516.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTS"
BASE COUNT        12022 a         8447 c         7251 g        13128 t
ORIGIN      
        1 acccttttct tttaagtctt taataaggtc agcaatcctt tccatattaa tataatccaa
       61 cccacttgta ggttcatcaa atagaaataa attagttttt gacaatgaag ctatagaaac
      121 caataatctt tgtttttctc caccggataa atcaaacggt aattgatctt tcattttata
      181 aagttccatt ttttttaaaa ttttttcttg ctgatcttta ctaactattt cattccccag
      241 ggctaactcg ctcctcactg attctgtgaa aaattggtaa tccatttctt gcattactaa
      301 aaacggcgat gacaaatttt ttttattttc gattatcttt cctttggtag ggcgaataat
      361 cttcatgagt attcttagta aggttgtttt ccccacaccg tttttcccta ccaaaccaat
      421 aacatctcca actttgacat caaaatttat gtcttttaga atattttcat aagtaatttc
      481 ttcaactttt aatacatctg cacttacctt ttcgatatag ggaacttcaa tcgaactatt
      541 aaaaatgtca aatttcctta atgcgttatt gttttcagtt tttaacaact gaatagttgt
      601 agtttttaca gttctatttt taacaaatag aacttgatca attaattctt tcaaatagta
      661 aaaacgatgt tcagctataa caatagtaaa tcctttattt tttaaatcac aaagtaagtc
      721 agcaagtttc ttagtcgctt tgaagtccaa atttgaagac ggttcatcca atataattaa
      781 tttagagttt agcgataaac tacatccaat agaaattttc tgccgttcac cacttgatag
      841 cgaaaaaatg tttttatcta atatatttga aagatctaat aattcagcta attcattgat
      901 tcttttatcc atatgctctt ttgtaaatcc aaagttttcc atcgaaaata ctaactcact
      961 cgttgtattt gttgtaaaga attgtcctct aggatcttga cttacgtagc caatattttt
     1021 tgatatactt tcttgtgtta aggattgtag cgagttattt tcaaataaaa tttccccaac
     1081 caattttccg tcataaagtc ttggaataag tccattcatt aactttaata gtgtggattt
     1141 cccactccca gaagaaccag taatcaatgt aagactgcct ttttttattg aaaaattaag
     1201 gtcaacaagc gcttgttcct taacatcctt atatgaaaaa gaaacattgt taaattcaaa
     1261 caattctttc acctcaaatc aaaatactta agaaaaaaat agtaacggaa aacaggatga
     1321 tatagtctaa taagctcatg tttgttttat agtaagaact tcttttcaca ggagattcta
     1381 tcccctttgt tattgcatta gcggtcattt cttcagcaat catagttgca cgtataagaa
     1441 cgggaactaa cagaaattcc aaatattgca gaggctgaaa aaaagacaag cgaatgtttc
     1501 tcatttttaa agattcttta atcattctta tttcagaacg ataagtcgga aagaatctga
     1561 tcactactgt aatacttaac attatttttt tcggtaaatg tattttttct aaagaggata
     1621 ataattcatt gctagtatag acactaacca acaaccatga gatcattacg accggcaaca
     1681 ttcgaaatac aatatataag gatgtcgcaa aaaatatagt aaaaaactct atcttgatag
     1741 catcaataat tttcattact aaaaacagaa ctgaataaat caagatgaaa taaatacatg
     1801 tctttatttt acgaaacatc aatactaaaa ctgtagcaat aatgaaacac cccacttgaa
     1861 atatatttcc ctttcctaaa aaaataatga ccggaaaaaa aatatttaaa gtaatcaagg
     1921 ttaacggatt gatttttgac actctttcac ctccaaaaaa taagatcgca ctgttatctt
     1981 aagctgataa aaatgcaccg ttattcagat aacagtgcga tcttatcaaa aagcataact
     2041 gagaacaatt ctcaatgcaa gcttttttta attaactcag taattcaatc cacccaggaa
     2101 cagaaaattg atacaatctt ctggttaata gcatagtctt ttcttttgaa tagctatgct
     2161 tcaatatatc atagaatgta gcgtagaatg agtaaatgta gaagtggatt tcttcttcat
     2221 taaagactaa attttgattg atcattccga tagtctttaa cttatctaga caacagactg
     2281 tctttttcgt cacaaatgat gtaatttttt caacaatatc ttgatatttg gttccagctg
     2341 attggaataa aatcaaatcg aatatacgtt tattctcaaa aatataatta ataaatggat
     2401 ctaattcatt gaagttctct ctccaacttt tctctatatc tatattttct aagtttaaga
     2461 ggtatttggt aaactcttca ttatacatat taataagcgc attaatatgc ggctgaataa
     2521 tttcttcaaa taacgcttcc ttagaagtaa aatgtttata aaaagcaccc gtagttacgc
     2581 ctgcggtcag gcacagttgc cttatcttag tttgctgaaa tccttctttt tcaaaatggc
     2641 ttagtccact ttctattaac ttttggtgag ttataatata atctctggtt tctatgggta
     2701 cttcctccta ataagatgaa ttaactttat tatcttacac aggacttgaa gtttcaatcg
     2761 ttaacgttta ttactgaact cattccttag agctaaacta atgagaaaga gcagaataac
     2821 tgatacaaaa agcaatccta caagaattaa tagactcatc taaatcattc accttttcta
     2881 aaataatccg agaaagattt aaaaaaatta tatccagcta ttaggataag tcctatcata
     2941 atcactccaa tagccatttt cttatcctcc ctaaaaataa agtcttttac ttaaaacctt
     3001 ttttgtaatc gtcaataaat tttttccctt tatcagttaa ttgaaatcct atatctaaat
     3061 agtcctcata tctaagttta gccagcatct cacttacaga tgctggacta acacttagaa
     3121 cttttgctaa atcattattt tttaatttct tttttctttt tgataattcc tgaattgcta
     3181 gtaaataaat tagtatagta gtcgttttaa tttgtaccat acctaccctc caaattattt
     3241 cgaaaggcct tcagcaattt tatccaggtt ccatttcatc atcgcatagt aactatcacc
     3301 atcttgtcct ttttctgcaa ttgaatcagt aaaaatcgtt gaatagatag gaatattggt
     3361 atcttttgat actgttttca ttggtctatc atccacactg ctttctacga ataaggaggg
     3421 aacttttgtt gtgcgtaatt tttcaactaa gtgttttatt tgatctggtg ttccttcttc
     3481 ttcagtgttg atttcccaaa tgtaagcaga aggcacatta tacgctttcg agaaatattt
     3541 aaagcatcct tcacttgtaa caatcatttt tttatcattc ggaattgaag caaatttaga
     3601 tttagcttct ttgtctagag aatccaattt ttcaatatac ttatctagat tttctttata
     3661 gaatttttta ttatcaggat ctttttccgc taactgtttt tcaatatttt tagcgtaaat
     3721 aataccgttt tctaaattta accaagcatg aggatcttcc ttccctttct cactctgacc
     3781 ctctaagtaa ataacatcta tgccatcact tgctgcaaaa tagtctttgt tttcctcttt
     3841 gttcgcattt ttaactaatt ttgtaaacca agcatttcct ccagtttcca agttaacacc
     3901 gttataaaaa atcaaatctg cttttgaagt tttttgaaca tcttcaggca aaggttcata
     3961 ttcgtgggga tctttcccaa taggtacgat actgtgtaaa tcaattttat cttttgctat
     4021 attttcggta atatctgcta aaatcgaatt agtaactact acttttaatt tttcgttcga
     4081 agccacttta tctttgtctt tactatttat tgaacatgcc ccgaatataa aaagagcaat
     4141 caaaatcccc agacttccca gtactgcttt ccattttctc atcataacga tctctccttc
     4201 tttcttaaaa atttttgttt tggtgagatt agaaaactaa ttacaaataa gaatgccgct
     4261 gttaaaacaa tacttgatcc tgctgctatg ttaaaactat aaccaataaa caatccaagc
     4321 aatgatgaac ttgctccgac tgttgcagaa ataaatatca tagttttcaa gctatttgca
     4381 tataaatatg ctgtagctgc tggtgtaatt aacattgcaa caattaatat agttcccaca
     4441 ctttgcatag ctgttactgc tactaaagtt aatagaacca tcaatagata atgataaaaa
     4501 ctgacattca tccctattgc ttttgccatt aatggatcaa aagaagtgat taataattct
     4561 ttaaaaaata gaactactat aaccaacact aaaaccgaaa cgccaattgt aatccactta
     4621 tcaatatctt gtacagctaa aatatttcca aataaaatat gaaataaatc cgttgagcta
     4681 tttgcaactc ctataaggat aactcctagt gctaaaaaag aactgaaagt aataccaatt
     4741 gctgtatctc cttttattac actattgctt tttataaaag taataatgat agaagctaat
     4801 agaccaaata caatcgcacc aataaaaaaa ttaataccta aaatataaga aattgctact
     4861 cctggcaaaa cagcatgaga aatagcatca cccataagag acattcctct taaaataata
     4921 aaacaaccta ctgttccaga aacaatccct ataactacag atgtaattag agcattctgt
     4981 aaaaagtgaa agtcatacag accattaata aaattttgaa gcatattatt ccccctctcc
     5041 aataaatata gtatctccat aggctttttt taaattttct tcattaaata cagattctac
     5101 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
     5161 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca atttttttaa
     5221 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
     5281 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
     5341 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
     5401 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
     5461 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
     5521 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
     5581 tccctgatga gggataatat ttaacattgc tttaagcaat gtggattttc cagcaccatt
     5641 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
     5701 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
     5761 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
     5821 ttttatagtt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
     5881 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
     5941 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttgaagtgga tagcgggttg
     6001 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     6061 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     6121 tgtttatcgt tattaatagt gaataggaaa aaaactattt ttgatcattg acaattaaat
     6181 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     6241 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     6301 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     6361 atgtgcttac ccaaagcaat tcaaaaattt cataactact attttaggag atgattttat
     6421 agaatccaga gtctacctga ataaaaaaca aacctgtgca tttctaggaa tcgataataa
     6481 tactctagat aagtggattc gtatatataa tttcccagta ataagagttg gtggtgtagt
     6541 tcgctttgac gtagaagata ttaaagactt tatgaataca tttaaaataa cttgaaattt
     6601 tcttctcgcc gcatatacta aaattagtga aatatactgc cttacttttt ttaaggagtg
     6661 aggattttgc ctacaaagct ttcaaatggg aaatataaaa ctaatctgag atatccaaaa
     6721 aggtttaaag aaataacagg aattgcatca gaaaagtatc aaaaaacatt tccaaatagg
     6781 caattggcga ttaaagccga aaatgatatg aagaagaaaa tagaaaaagt tttgagagag
     6841 gagaatgcaa actcattaga attaaaagga aaaataacgt ttaaaaaatt ttacgaatct
     6901 aaatggcttc ctagatatga attaggtcaa acaattagat caaacaggcc tcctagtgat
     6961 ataaccatta gtaatacaaa agatatattt cggttgcata ttttacctat gtttggtgaa
     7021 tacgcaatga attatctaaa tatcaatact gagataatat cagatgaatt aaccaaaaaa
     7081 tcgaaagaat atgcaaatat aaaaatcata aaaggatatg ttcgttccat gttcgatatt
     7141 gcagaaatac taaattatat cgaatttaat cgaactacta aaattattca aagtatcact
     7201 gcacctaaaa aaaatgcttt agaagaaaaa agaatacaag aaggtaagca agcactatca
     7261 tcaaaagaac ttactaattg gatagaagca gtaaatgatg attttaataa tcatttactt
     7321 acttttcatg attacacact ttttatgatt accctgtatc ttggtgatag aaaaagtgag
     7381 acttacgctt tgcaatggaa atatattgat tttgaaaaac aaacggtccg tcttaaacat
     7441 actttagata aatatcaaag aaaaaagttt acaaaaggtc gaaaagatac cgtcattcaa
     7501 gtaccagaag ttgtaatgac attgctaagt gaatggaaat cggtacaagc tgatcaattg
     7561 ttgaaattaa aaattaagca aacgttagat cagtatctct ttacttatac taaaccatct
     7621 ggagaagtaa attgtcctgt tcatgccgat tacctaaact atcgaatcaa ttcaattaaa
     7681 agaaggcatc ctgacttagt tcatttatct ccacacaaac tccgtcatac ttatgcaact
     7741 atagctagac aaggtggagc agatatgaat caaatttcaa atgctttaac acactcagat
     7801 atttctacaa caaagatata tgtgaacaca ccagatatag ttgataaggc tgtttttgaa
     7861 gcttttcaga gaggattgaa taagtgtgat tgatatgtgt tcttaaatgt gttcttaaaa
     7921 acaaaagaag cactttccaa ataattgaaa agtgccagaa acgttgatat ataaaggata
     7981 ttaacgtttt gagaattgtg aagctttacg tgctttctta agacctggtt ttttacgttc
     8041 gaccatacgt gcgtcacgag taagtaagcc agcacgttta agagctaaac ggaagtcagg
     8101 atcaacttct agcaatgcac gagcgatacc atgacggata gctcctgatt gtccagcgta
     8161 tcctccgccg tttacgttaa caaatacgtc atatgcgcct tttgtttcag taacagcgaa
     8221 aggttgattg attacttcac gcaagtcagc atgtggaatg tattcttcaa catctttttt
     8281 atttacagta attttgccag ttcctggtac tagacgtacg cgagcaactg cgtttttacg
     8341 acggcctgtg ccgatatatt gaacttgtgc caatgaaatt ccctcctatt agattaagtt
     8401 tgtgatgtct aaaacttctg gttgttgtgc tgcatgtgga tgttctgctc caccgtatac
     8461 gttcaatttt gtaaattgtt tgcggcctaa agtgttttta ggaagcatac cttttacaga
     8521 agtttcgatc aaacgacgag aatttttagc acgcaattcg ccagcagtga ttgatttcaa
     8581 tcctcctggg tagttgctgt gacggtaata aattttgtca gtcgcttttt tacctgttaa
     8641 tttcactttg tctgcattga tgacgatgac gaaatcgcca gtatccaaat gaggtgtgaa
     8701 agttggttta tttttaccac gtagtacaga tgcaacaact gttgaaagac gtcccaatgg
     8761 aacatcagtt gcgtctacta cataccattt acgttctact tcgcctggtt tggccatata
     8821 tgttgtacgc acgttatttt cctccaattt aagttctgat gtttgacata cacttcgagt
     8881 ttccggggct ctttgtgggg caaacaatac catttaacat attacccgct aatctagtca
     8941 atgtcaacgt ttttctgctt gattgaaaaa tttatatgaa actttacttc ttttctttct
     9001 tttatataaa agggtcgttt cctgtcaaaa tgaaaaacaa aaagaggctg tgacaaaagt
     9061 cttgtcacaa ccccttattt tgaataaacg gtgttctcct gccaactcct cggtcacaag
     9121 tcacaatatc cataaaacat aagaagctgt tttttaaaat tgtttcttgt gactcggagc
     9181 tgaacggcag gcttacaacc tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta
     9241 gctcaaaaaa cggcaaaata tgaggaacta ttttgacgtt tgtttctcta atactcaggt
     9301 caaaacgctg atttcacaac ctctttttcg gtcaagttca acaacagttt ttacgcgtcg
     9361 atctctggcg ctttgcccaa atgagcttgg atcatccaga tacgtttttc tgtggctgtt
     9421 ttgaattcga taaagatatc ttgtgttgga tcgtcgcctt cttctccaga aacttcgatt
     9481 cctttttggt aaagatctgc tagataacga tagcctgcaa caagtgtttc caaacgttct
     9541 ggaatagtac gatcccagcg gccaatttca tcagggattt ttgtgttatc tgcaaattca
     9601 cgcaatgtag aataaggtga accgtctaat gtgatcaagc gttcggatac ttcatctaac
     9661 tgagcgttca aatcatccat gaactcatcc atcattgggt gcaatgtaag gaaacctggt
     9721 cctctcatgt accaatgtgt ttggtgaaca acaacagaca tttggcttag atctgcaact
     9781 aattgattta atacttcttt ggtttgttgg aatttcatct ttcttgcctc ctaacatttt
     9841 cttacactta aaataatagt agactttcaa tgaaaagtac aacaaaatca tttacctgag
     9901 aacgattttc agttcgcttt tttatccgta aagccaatca tttttcagaa tcagctaatt
     9961 cttctcgcag ttgagcaaat tgctgataag tctgtgctaa atgcttttgt gtcgaaacaa
    10021 ataatggata gattttctga tattttttat gatcagtttc ttgtactcca acttgctctt
    10081 tcaattctat caattcctgt gcttcactga tactttggat ctttccgatg cttctccagc
    10141 ctaaaatcac agctcctaat gcggatgctt ctgtgacagt agggaaaaca agcgggtaac
    10201 ccagtacatc agccatcatc tgacgaaaaa tcggagattg agcaaacccg cctgtagcac
    10261 ggatctctgt gagctgattt tcctggcaaa ctccttttaa aatccgataa aggttgagac
    10321 agatcccttc tagaatcgcc ttcatcattt ctttttctgt atgttgccgc tgtaaaccga
    10381 taaaactgcc aaacgcatct gcgtcccaaa gcggtgctcg ctcaccaagt aaatagggat
    10441 gaaaaatcag accattggca cccgctggca caaaagcgat agccgaaagc agtgcatcat
    10501 atggattttc tcctttttct ttagcagatt gaacgacttc ctgtaaaaat gtatgccctg
    10561 cccaatcaaa gatgccagca ccattgctag tcgctcctcc cactacccaa tgtttctgat
    10621 ccagaacata acaaaacgtc tccatttctg gatggaactg aggctgagta gtaataaaac
    10681 gaagtgctcc gctcgttcct acggtcaaag cggcgatcgt atcaccaaaa gcacctaacc
    10741 ctagattaga aagcggcccg tctgcccctc ccaaaacaaa tgatatatca tttggcaaac
    10801 ctagttctgc tgctgttttt gatggtagac ctgttacttg ataggtggaa ggaaagactt
    10861 gcggcaattg ctctattcga atgttcaagt agtcaagcac ttcttctgcc cattggaatt
    10921 catggatatc aaaatatcca gttcctgaag ctgttccgta gtcgctgatc agttcgccaa
    10981 acaatctata aaagatatag tctttgatac cgacaaaata agcagttttt ttgaataatt
    11041 caggttggct gttttgcagc cacttgattt tgttcaatgg tgtcattgga tgaatcggcg
    11101 tcccagtctg ccgataaaat tctttgccaa gcacggtata tttcagtttt tctgcttcgt
    11161 ccgctgctcg gttatctgcc caagtgatca ttcgagataa cggtgttttc tcttcatcca
    11221 acaatatcag gccatgcatc gcagaggaga aggagacaaa ttgaatgatt gtgtctgaag
    11281 gcaactgttt aattacttct tttataacgg tgcagacacc ttgaaagatc aattcctgat
    11341 cttgttctgc catcccttgt gtttcttgga tcaaagggta gcgaaaataa gcggatgctg
    11401 cttcttgggc ttcatctgtg aaagcaactg ctttggtttg tgtggttccg atatctaatc
    11461 cgattgaaac gttcattttt tcacctcaaa ttttatgtat gtacaaaaat ttagtttaag
    11521 cttgcgtatc ttggttttga aaagggggag atggcgtgtt actttatttt atcattggtt
    11581 gctgtatcgg atcattttta tgtttaaccg cccagcggat tccgttaggt cactctatta
    11641 tttatcctag atctcattgt gtcaaatgct gtcgttcgct ttcttggtat gaattgattc
    11701 cgattctctc gatcatcgtc caacgatttc gctgccgcta ttgcaggtgt cggttgccct
    11761 tctactattt gttggcagaa gccttatgtg gtggtctttt tgcctggttc tttacttttt
    11821 cttccgcaag aaatttttcg acgttcatat ggatgctttc ggctttgcta ttttcgttga
    11881 tggatttatt ttacttcatg gtccattctc acacgctatt ctgttcttgg gcaattttat
    11941 ggattttttg gttgcaggcc ggcgtcttcc aatggcaaag tgtgctgtta acgtttatcg
    12001 taggcggtgt gtgccttcgc tatggtcaat cctatctcgg agctggcgat actctgttga
    12061 tgctttcttg gagtggtggc ttgtctctag aagagttgct tcagatcttg tttcttgcta
    12121 gtctgtttgg aatatccgtt ttttctgttt actttatctg tcataaaaaa aagttggaaa
    12181 agctgccttt cattcctttt ttgagcagtg cgttgctgat tgtccttcat cttaggtatt
    12241 gaaaaaaggt tgtgacaaac gacttgtcac aacctctgat atatagtgtt ctcttaccaa
    12301 atccttgtga cttggagcta ggcgacaggt tcacaacctc tccactaaat ggtgttcaat
    12361 cagctgaccc tcagtattag ctcaaaatgc tggttttaca acctctgata tacggtgttc
    12421 cataagtagc tttttcggct tcttatttct tgacgcccca atgtcgacga aggaaacctg
    12481 cacgtccaga accttctcga taaagattgt aatggagctt gtttttcttg taataatcct
    12541 gatggtaatc ttctgcagga taaaattcgc ttcttggttc gatttttgtc acgattggct
    12601 tatcgaatcg cccgctgtct tgcaatgctt gttttgaacg ctctgcaata tttcgttctt
    12661 cttcatcatt atagtagatc actggacgat aagaatcacc gcgatcagcg aactgtccta
    12721 atgcgtcagt cggatcggtt tgctgccaat agatttccac caactgatca taagaaataa
    12781 cttctggatc atattcgatc tctactgctt ctgtatgccc tgttgtgcct gttgttactt
    12841 gttcataagt tggatttggt acatgcccgc cagtataacc ggatgtcaca gaaatgatcc
    12901 ctggctgctc ttcaaatggt ttgaccatac accaaaagca tccgcctgcg aaaactgctt
    12961 tttttgtcat ataaaatccc ccttttttct catcatacct tgatttccaa aaggaggata
    13021 acgttttgct tgtgacagaa aaaacggaaa ctattatata cgtgatacgg cttctgataa
    13081 atgccaaaac gaacgtactt gatcaaaaac ggttaaatca ggaatcacat attcagcaga
    13141 aggaagattt atgttttcac ctattcccaa tacatgcatg ttaccagcca aagctgcttg
    13201 acaaccagct tctgaatctt caatgaccaa gcatgcattt ggcggtacat tcaattgctg
    13261 tgctcctttg agaaaaactt ctggatcagg ttttgctttt gatacttgcg tgccgtcaat
    13321 aaggacatca aaataacttg tcaaattcgt tttttctaaa atgaggcgtg catttttgct
    13381 tgctgatccc aatccgatct tgatgtttgt ttttttcaag tactcaagaa cagctattgc
    13441 accaggcaaa acggatgttt catccatttt ttgaatcgct tgaagatata gattgttttt
    13501 ttgctcagca aaggctgatt tctctttttc tgagaatttc tgttccattt ttccaaatga
    13561 cagcaatcgc tctagtgact cggttctgga tattcctttc agttgctcgt tttctttctc
    13621 agtgaatgga atggacagct ggttagctaa aaccagccac gcttcgtaat gataacgagc
    13681 tgtgtctaca agaacgccat ctaaatcgaa tagtgctgct ttgattttca tcgattacct
    13741 ccttgaaaat gaacgacttg aagtaaagat gcgatgtttt tagctgtgcg atgaagatta
    13801 tcagtggctt gctgtaaagc ttcttgtaaa ggcacagctg caggaaggat cggaaaaacg
    13861 gccgaaatgc caacatctgc tgctttttcg cttcctttac caacacttcc gcaaatagct
    13921 atcacaggaa cgccctctgg tactcttcta gcaatcccaa ctggcgcttt tccttttaga
    13981 ctttgtccat ctagacgtcc ttcgcctacg attacgaggt ctgcttgctg tacccgttta
    14041 tcgaactcca gtaaatccaa tacgtagtcg atgccagaga ctattttccc tgaagcaaat
    14101 gctaacagtc ctgcacccat tccaccacca gcactactgc ccgatgcctc gattacttga
    14161 ggggcaaatc tcatataaaa atcatgcatg gcttggtcag ccactgctaa ttcattttct
    14221 ttcaagcctt tttgtggtcc gaaaacaaaa gaagcgcctt cttttccgca taaaagatta
    14281 gtaacatcag taatgacagt gattttggct ttaatcagct caataggcac gttcgtttta
    14341 tcaactgtag caattttacc tagattttct cccagtgctt ctactttttg attatcttga
    14401 tcgtaaaaag cataacctag accttctgcc atgccgatgc cgccatcgtt ggtactactt
    14461 ccgccaacgc cgatgatgat gtgtcgaaca ccttgttgca acaattgtcg tatcagttct
    14521 cctactcctc gcgtggataa cctaagtggc tgttgttggt ttagtgggac atctttcaat
    14581 ccgacgattt ctgccatttc aaaaatcgca gtttgaccgt ctgaagcgta ctggatttct
    14641 ttgtttttgc caaatgcatt agtaacgact gctgtttgcc gcttcaacct taaactgtct
    14701 gctaatgatg aaaccgttcc ttctcctcca tcgcctatag gtagcagatc atattcagcc
    14761 tgaacaaaaa cttcttgaaa acctgattga atggcttgtg ctgcctctaa ggctgtcaga
    14821 ctttctttga aagaatctgg cgcaatcaga atacgcatta ttttcccctc cgttccaaga
    14881 tcagttcttt ttccagctgg tattggtctc cattgacaaa aataggtaat gtttctttcg
    14941 tctctttttt tattactatt tgtttttttg tcaaaacaaa tagcaacctg tgatttttcc
    15001 aaataaaagg aaaagaaatt ttttcccatg ctgaaggaag tcttggagaa atagaaagag
    15061 ttccattcgt tactgtaata cctgaaaaac caaatataac tgctagccat agtgctccta
    15121 atgaagcagc atgaattccg tcatctgatg aatgcggatc tggtcctaaa tcaatcaggc
    15181 acgcttcttg gaataaatga tacgcccatt ccatttcttg gatacggcaa gcctctatgg
    15241 cgtgaatcgc tttactcaac gatgagtcgt ggattgtttt gttttcatag taatgcaaat
    15301 tcttagaaac gattggttga gaaaaatact caggtaataa gtataacagc atgacaagat
    15361 ctgcttgctt gctgacttgg agttcattta cttcgctacg ggcataatca agtaaaatag
    15421 actggctgcc aggacgttct ttgtaagtgg tcaaatcaat aactggctta ctgagatacg
    15481 tgtcatcttg cggaatcagc tgttctttgt taggcactgg caaatataac ttatctaaaa
    15541 aattttgaca ttctttcaaa aaaagcggat cgccagcttg atatttaaca gctaaggcca
    15601 cattataatg cgccagatag ttcgtatatg cattattgtc gatatattct gtgtattcat
    15661 ctggaccaat gactctgtgt atctctaaat gatcatcgac ttttacagct ctgctcagcc
    15721 aaaaagctgc tgtttcatga atgagcgttt ttccctttgt ttctaaaaac gattgatcct
    15781 ctgttgcttg gacatactct tgaacggcat aagcaaggtc tgcactgata tgatgttctg
    15841 cggcagctga agcaacttct tgtcttgttc cggttttgat attcaatgca gcaaatttgg
    15901 gtgtctcttc ctgaccagtg tgtgcgcttt cccatgggaa aagtgcacct tgatagtgat
    15961 aatctcttgc tttttgccgt gcgccttcta atcgatcata acggtacagc agcaaattct
    16021 ttgctacttc aggaaactga tataaaaaga aaggcaggat aaaaatttcc gtatcccaga
    16081 aaacatgccc tttataacct tcgccagtta gtcccttcgc ccctacacta acacttggat
    16141 cattgcgggg agtcataatc tgtaaatggt aagcagcgaa gtccatcgct aactgatcga
    16201 aagaagaatc gccttggatc gttatccgat gctgatgcca aaaatctgtc caataagaca
    16261 tcgactgctc taaaatttct gtataactaa cgcttttctg ggcttgggca atacttttct
    16321 taaacgggtc tgtttgctga agagaggtag agagcacgat gatcttctcc agcgtaaagg
    16381 acgtattttt tctgatcttt tctgaaaagg aagcggtgat ccggcgattt tttgcttgga
    16441 atacacctgc tttattgaat ttagctgcaa tcccaatatc aattttactt tctgttgtct
    16501 ggtaggatgc actgatcaaa tcgtcaccaa atactcgcag ttctttttca accaactgct
    16561 gtgtaccaaa attggtttgc tgtccatcga tacccgtttt cacatctact tggcagtctt
    16621 cggtcaacgg cttgatgacc actttcaggg ctgcctgatg gagattattt tgatcagcaa
    16681 cacgacaagt aatgacttcc actttttttc cttgagcagt ttcaatgagc gcatagcgtt
    16741 taagctctcc catttctaaa tctagtgccc gctcgtatgc aagaactttc atcgtctcaa
    16801 gagaaaaatg ttcaccgtcg atttttattt cccatctgat gacatctggg agattcacta
    16861 actcggctga ttctgctcct aaaggtcggt tatatacacc agctgcaaac attcccctta
    16921 cttgattccg atagtcttcc tcctggcttc ctctgatacc aaaaaatcca tttccaatgg
    16981 tcatctgact cgcatactta ttgatatact ctaaatcaaa ctgtttttct tctactttca
    17041 taaggtaata acttctcctg tttctgccga acgatataaa ttttccacca gattctggat
    17101 gacatatcct tgccagccat ctgcaatcat ctgagtctgg tcaccgagcg cccgattcac
    17161 aaaatgagcc atacttagtt catgtgggtc attaactggc gtggtctttt gtaaggaaac
    17221 cagctttcca tctacatctt cgaatagttc gcctggatac agattagcac ctgcctgatc
    17281 gccacaaaaa gccacattca gtttgtcttc tctgatattc aaagcaaacg aagtattcag
    17341 ttggatgatc ttgccgtttt ctaattccag tgtgccaaaa attgcatctt ctactgtgaa
    17401 tttgcttgga tcccatttcc cgaatttccc tgaatttttt ttcgtaccaa ttttttggaa
    17461 gctgtacgcc cgaacgcttt ttactttagg aaatccagta atatacatcg ctgtatcaag
    17521 catgtgaatg ccataatcga tcaaaggccc gcctccttga agttctttgt cgataaacgt
    17581 tccccagcct ggaacaccag accgacgaag cgcattcgct tctacgtaat aaatatcccc
    17641 gagaacatca agatgattct tgatcattgt tgcttcgtca gaaaaacgat gctggaatcc
    17701 ataagccaaa atctgcccgt ttttatcggc tgtctctgcc atctttcttg cttgatcagc
    17761 tgtcatagct ggtggtttct cgcacatcac tgaagcatta gcttcgaggg cagccaatac
    17821 atgttcgaag tgaaagcgat tgggtgtaca gacactcacg atatcgggag aaatctcatt
    17881 cagcatttgt gtaactgatg tatacgcatg agaaaatcct gtacgtcggc aaaagtcttc
    17941 tgctcgctgg ctgactggat caaccacagc ggccaattct aagacatctg atcttttttg
    18001 ataataagca gcatgtactt tttctgctac ttgtccagcg cctatgattg ctactttctt
    18061 catttatttc tctctccttt gcttatttac ttattgttat tctttctcta ttctttctct
    18121 aaatcattta aatgacgcgc tgtttccaga cagtttttca agtattgcaa tgattcctga
    18181 taaattttca cttcattttc tcctcgcaaa cgacattcat ataccatata accttcatac
    18241 tcattttgaa gtagcgtttg aaaatggcga gtaaaatcaa ttgcgccaga tcctggttgg
    18301 tagcgatgat tatctgctaa atggatatga cccacatact ctttttgcgt agtcaatgct
    18361 tttgaaatat catcttcttc aatattcata tgataaaaat cagcgatgat ctgcacatgt
    18421 ttcaattgat tagagtcaat gtaatgacgc gcatccgcta acaaattgat catatggtct
    18481 tggtatcggt tcaaaggctc caaataaata accgtacctg tttcttcggc tactttatct
    18541 aaataacgaa gtgattcgct gactgcttta tagtctcctt ctttgcttcg gggtgaaacc
    18601 atcggcggta atcgataagt gaacattccc caagctgctg ggataacgat tcctttgcct
    18661 ccaacctcgc ttagtgcacg caaaatctca gcaatttgac gtacaccatt aagacgccgt
    18721 tcttcgataa agtcaccgat ccacccatcg tagccgttac aagctgtcac tactgggatc
    18781 cctgtttctt tgattgcctg tttgactgtg tcgatatttt ctattaacaa cttaccgtcg
    18841 atttcgtatt cttcaaatcc acagtctttg ataaatctaa atttttctaa aatgtctctt
    18901 gggaaaaatg cttgatcttg cgtaccgaat ttcattgttc tcctcctcgg acttgaacgc
    18961 ccattttgat actttcttct gggtgctggt ctacataacg catgtaagct tctgcgcttt
    19021 ctgcaaatgg cacaactgga tcaatgattt cttcacaatc caagtaaccg ttcatcaata
    19081 attcccaaca tgtgtcctcg attcgtttac ggttccatct tgggtaatct gggtttggtt
    19141 cactagatgc tcgagcaaag acgatttttg cattattgaa atgtgcttcg cgaccaagat
    19201 taaacccagc tggaaaaggt ttagcaaagg caacataaga aatgatcccg ccatagccga
    19261 tccctattaa agaagcttgt aatgcggcag cactgccact cgtttcaata actgaatcta
    19321 ctccacgttt atctgtcaat tcctttagac gaaaaccgac atctgctttc ataggatcta
    19381 gcgtgtaatc ggcaccgtgt ttttctgcta attctctacg ctgcgctatg ggatcgatcc
    19441 caacgatggt agtagcacct gcttttttag ctaattgaat cgcaatttgc ccgatagcgc
    19501 ctaaaccgaa gattgctaca gcatcacctg ctcgaacatg tgcttcccgg ataccaccta
    19561 aagcgaattg agcaggatcg taacatactg catttttcca ttgatccaac cgatcaagtt
    19621 tacgtagttt ataattatca acaccgtttg taatcagcgt ttcacgaatg ggtccataag
    19681 tgcagactaa ctctcctttt tgatactctg tcaccaaact gcccgtttct tcgatcgtac
    19741 cgacaatcat atttcctaat tgaaattcgc caaataccac accgcgttgg cttccttctt
    19801 ctcttggcaa gaataggcgc cattcttctg aaaattcttc atcgataaat ggacttaatc
    19861 ctctaaagtc gacaatttct gttcctggtt ttggagtagc gaaaattact cggatacgta
    19921 cttcgttctt ttcgatctca cggtcttcgt aatctttgaa tccggctatt cttggttcta
    19981 atgcaactaa ttttttcatc ttttctttcc tctttctttt ctttttatcc ttttacgccg
    20041 ccttcgacta aatcaccttt aataaatcgt tcagataacg catacataat gatgactggt
    20101 aaagcggtca ccaatgaagc ggccatcatt cgtccccaaa tgtagtctgg tgtactgaat
    20161 aatgtgttca aaccgattgg taaagtaaat ttttcggagg tcgacaggaa aatcgaagca
    20221 aataaataat cattccacga aaccataaag caataaacga agacagaaat gattccagaa
    20281 atagccaatg gtataatgat ccgaataatg atctggatcc ggctaagacc atcgatcatt
    20341 gctgcttctt caatatcagt cggaatcgtg tcaaaataac tttttagcat gaatatcgca
    20401 gtaggaagtg tttgaacgac catcgtgata atcagtgctg tattggtatc atacaaacct
    20461 agaccggaaa tgattttaaa taatggaaca acgatcaaaa taccggaaaa catataaacg
    20521 gtgtaaaagc tagcattgat tttcgagcga gctttgaagc gtagttttga caaagcgtat
    20581 gccccgctga tcccaatcac tactgcagtt acggaggcta tcaaggagat cactaaacta
    20641 tttttgaaat acatgatgaa tggaaaaatc tcagcattga aaatatcctg ataatgttca
    20701 aaagtccatt ctttcggaaa aatagtttgt gtcgttgcaa ttgcttcttg tgaatccttg
    20761 aatgatgtca tcagcatgat caaaaatgga aacaaattga cagctaatag caacaaaatc
    20821 gtcgcgtaaa ataagatttt cctgctcttt ttatttttca tttcaagtcc accttctttc
    20881 gtgagagcaa gacgaccgct gcaataatga tgaacaatag aatcgatata gctgctgctt
    20941 ttccaagatc attgaacgca aaggctgtct gatacaaata aacgcctaag atattgactt
    21001 tattcgtcag tagatagaca tctgtaaaca tatagaacat ccagatagat cgtaaaacaa
    21061 tcacagttgc tagtactggt ttgattgccg gcagtgtcac gatcttgaac ttctgccaag
    21121 catttgcacc gtccatttca gctgcttcat aaagcgtttt gtcgactgtt tgcaaaatag
    21181 ccaaaaatga aataaacgca tacggatagt atctccagat agcaaacaaa acgaccataa
    21241 agaagctagc aactggctgg tcgaaccaca gcggtgcttc gttgaaaagc tgcaacctat
    21301 ctactaacag atcattgacg attccataac tattattgaa catatatttc caagcaaaaa
    21361 tcaaagaaat agatggcgta acataactta ataaaatcag tgaacgcacc gttttcctaa
    21421 atctgaactt gcggttaagc aaaatagcta cggctaatcc taaagctgta ctgcctgcta
    21481 caactaagaa tgtgtaagca actgttaaac ctaaagaacg ataaaattca ctatcactta
    21541 aaatttcaag ataattgctt aatccgataa aaacggcgtc tgagttagga ttcagcggca
    21601 tatcgaaaaa actgatctga atattggaaa gcattggaat cagcactaaa acagctaata
    21661 aaagcatgct tggtgctaaa agtcccatgg ctaattttaa gtcagaatgt ttccttggac
    21721 gattcattga aacctccccc tgataatctg ccaatagcta tctacttttt tcgaacacca
    21781 ttggcagaac ttcttgttat ttcgtatttt tttgtgcgtc agctaaagct tgatcgacat
    21841 cttcgtttcc gacagttact tggttcactg cttttccgat cacacctgag cttgtgatat
    21901 ctcccatttt cgtgaaattc ttttccccga ctagtccaaa gacttgtact tcatcaaaag
    21961 cactagcaat ctcagatggc agctcgccaa aagacttgat gacttcattt tctttgtaac
    22021 catccagttc gactacttgt ttattcactg gttgagcacc accaggagac atcaagaccc
    22081 acttttccat gtttttcggt tgagataaga aagctgtgaa tgcttcagca gcctcttttt
    22141 gtttctcgtc tagaccagaa gaaatcgtca atccagatac tgtgccatag acagcttgat
    22201 ctttttgtgt tgggatagca aaaccgatat tttctgagtt ccccgcttca taaacagaag
    22261 gcaaaatgta agttgaatag attgccattg gtgctgttcc attcatgaaa gcatctttga
    22321 tttctgtcac atcattagag cctggcatcg tgtattggga taagttttga taaaacgaca
    22381 atgcttctct catcttttcc gtatcgatcg ttacctcgcc ttcatcatcc aaaacatttg
    22441 ctccatttga caaagcaaat tgagagaacg cttgctcact cattgttcct tcagcagtag
    22501 gcatagcaat tccatattgt ttattctctt tatctgtgaa atgttgagca atttttaaaa
    22561 tatcatccca attttctggt tctgaaaaac cagcttctga taatttttct ttgtcatacc
    22621 aaataccttg aacccagccg ctaattggtg cagcaatata gctttttcca tcttctgaac
    22681 gaacaaggtt tttggctccg tcataataat tatcttctcc agcttcctcg ataacgtttt
    22741 ggactgccgt ctgatcaatc agttcatctt tatccatcac tttagcaaaa tcctgactga
    22801 cttccattac ttctggtaat ttaccggaac gagctaacgt aacgattttt gtattgaacg
    22861 ctgattcttc taccggcact tgcttgattt tgatgtctgg attttctttt tcaaaatcag
    22921 caaccagttc attgatcaca cttaatcgtt cctgttcgac agaagagtgc atgaattgaa
    22981 tcgttgtctg ttgtgattcg ttagagcttt gactttcacc acaagcagta agaagaaatc
    23041 cagtagctag cagacaggta gtaacaataa tttttttcat ttttttccac ctcttatttt
    23101 attattttca gccacatata ttcatacggc tggaatatca actttcgttc ttgactgcaa
    23161 tggataattt gtccagaaaa caggtctagg taatctcctt ttggtaaaag ataacctgct
    23221 gattgattgg aaaaattatg gataactaag actttctctt ccttcgcttc gcgaataaaa
    23281 ctgataaaag aatctgctga gtccagtaag taaatcaaac tattcggatg gaaggctttt
    23341 tctttttttc gaatagatag catctgggtc aattcaccat atactgctgt tcttaatgga
    23401 tctgtctgca actctttctc aatatctgct aacaaaaatt tttgccgatt gatttttcga
    23461 ttctctcctg ttttttctac gcctttgtaa tcatttcgac ttcccagcac actttgaata
    23521 taaattgccg gcacgcctgg taacgttacc aaaaatgaat gagcagctaa aaagcgtttg
    23581 cttctccatt ccgtcgtatc tgttggagaa cttaacgcat ctagatacgt agcgtttatc
    23641 tcatatggac tggtcgttcc atctgggttt ttcttgtagt ttactcgggc accctctttc
    23701 ttcagctgtt ccactaattc aaggatcgtt ttttccggca gaatacctcg taccggattc
    23761 aatccgatac cgtcatggga ggctaaaaaa ttaaaaaaag ttgttttttt cgatgcgaaa
    23821 tcgatggttt ttaaccattc tttcaactta cttgtattac ccgaacgaat cgcttgaagg
    23881 gtcaaaggtg gtagcgaaaa ctgatagacc atctgtgctt cattctcgcc attcccaaaa
    23941 taactgatat tatctttgtg tggcacattt gtctcagtga tcaataccgt tcctggagct
    24001 gcttcatcag cgattgcacg gaataattgg atgattttat gcgtttctgg caggtgtata
    24061 caagaagttc ctagttcttt ccataaaaat cccacagcgt ccaagcgaat aaatgaagcg
    24121 cctttttcta agtaaaacaa aagaatatcg atcattttca ataaaacttc tggattttta
    24181 aaattcaagt ctacttgatc ttcgctaaaa gtcgtccata cgtgtttttc tttcccgttt
    24241 ttgtcaatga acgttgtaag taacgggctg gtccttggtc tagtcacgct gcttgtatct
    24301 gtatccagtg gcaaatcaat aaaaaaatct ttgtacgtat cattcaagtt taaatattcc
    24361 tgaaaccaag tactttcggc agacatatga ttgcagacaa agtcgaacat taaccgtgtt
    24421 tcgcttctca tttcttctat atcttcccat gtgcccaaac ggtcgttgat tgcctgataa
    24481 tttacaacgg agaaaccatc atcagatgta tatgggaaaa atggcaagaa atgtacaact
    24541 ctaaatgtat ctgccaaata cttttgataa aatttcttaa atgtacgcaa agttggttgc
    24601 tgctcttcaa aaaattgatc cccataagta atcaagaaaa tatcttcttc gtcccaatgc
    24661 agtttgcctg cctggccttt cttctgctga taaacactga ctttttgttc aatcatagag
    24721 gcggttttct cagacaaatc tgagtcgcga taaatcgctt gtaaaagttt tgtatacatc
    24781 ggattcccct ttcttttttg ggagcgttcc caacgatttg atcatattat ggaaaacgct
    24841 tactgtcaat agcatttttt taaataattt tgatatacac aaaaatacaa ataagaaagc
    24901 ttatgtatca ataattaata gcttcttaaa aaaatatggt ctctcatgat catgcaagct
    24961 attcctaaat tttcaaaatc atagacaaaa aagaatgtct attgtactat ggaattattc
    25021 taaaacgctc ccaaaaagga ggtgcatata aaattgaaac ctactattta tgacattgcg
    25081 aaaaaagcta atgtctcaaa atcaactgtc tccagagtat taaataacca gccaaatatc
    25141 tctgataaag caaaagcaag tgtacttcaa gcaatcaaag aattgaatta tgaaccgagc
    25201 aaaattgcaa gaggactgtc aggaaatggt tttgacgcga ttctagcatt atctcatcgt
    25261 acttctcata cgacctatgg caatcctttt ttttcagatg ttattcaatc catttctgcc
    25321 gtttctgaac aaaataactt cgacttgatt ctacaaacgg caaaaacacc agaagaagag
    25381 ctagaaaaat gcgcgaaaaa gatccaagaa aaaatgatcc gaggaattat tattttaagc
    25441 tctacgatgg atgaaacact tctttttgaa ttggatcaat ataatattcc tattgtggta
    25501 atcggaaaag tcggaaacga ctacacgaac atctactcag tggacacgga taatttccag
    25561 gatagttacg atttggtgga aacactgatc aagaatggac accgtcatat cggctgtctc
    25621 catgctccga cagaagttta tgtatccaat gatcgtctca atggttaccg tcaatgctta
    25681 tttgatcacc acctagatat ccgtaatgaa tggattatag acggcggctt tcgcttagaa
    25741 gatagcatgg cagcaatgaa tgatttaatg aagctacgag aaagaccaac tgcgattttt
    25801 tctaccgatg cattaaaatc attgagtatt tacaaagtgg cagaacaatc tggaaagcag
    25861 atacctgatg atctttcgat cgcaggattc agtgatccct tattgtcctc cctattttcg
    25921 ccacagttga ctcggataga cattccgaca aatcagttag gaatcaaagc cacagaactt
    25981 ttattccaac taatccacca ccaataccct gaagaaaaaa gaatcattct ttcaaccgag
    26041 attactctca cagattcgat ccaacaacaa gaaatgtaga acagaattat aaaagaacag
    26101 aaacactgag gataagtcag ttactctgtt cttttttcaa tcactcatcc ctcgttaccc
    26161 cctcccggta ttttagcgaa tttttcttat tttccatctg ttttagatag ctgtggataa
    26221 ctataatgtt tgtgttaaac tattttttcc acagggaaga aaaaactatt tttaaccacg
    26281 ttgtgtataa gtttttatag ttcgtttttt taaacacatt tacccttatt tcaatccatg
    26341 ttatttgggg atacttatct ctaaaacata aatagaataa cagacatgtc tactggtttt
    26401 gttttattcg aggaattatt caataatagc tagcaaaata ttaaaaataa ccgctctatc
    26461 ttcccatcaa tttattttgc attcaaaaaa tgatctatct ttacttttgt tgattgactt
    26521 ctcttggaag atgatcgttc cgatacctta attggatacg aaccgatgtt gttaagatcc
    26581 tttcccactt ttcttctagt tagacaaatt attttagaca aaccaaaaaa gaggttgtga
    26641 caataatttg tcacaacctc ttttttaaaa tatctatttt gtttgattgt tcattgcgtc
    26701 ttctgcagcc atttgcgctt caatatctga aatactgtag acattttcgc ttgctacacc
    26761 gacttctttt ggttccatgt cacgataacg ttgcatacca gtaccagctg ggatgatctt
    26821 acctataata acattttctt tcaaaccaag aagaggatct ttcttaccgc ggatcgcagc
    26881 atccgtcaag acacgagttg tttcttggaa tgatgcagca gataagaaac tatttgtttc
    26941 taatgatgct tttgtgatac ctagtaagac aggtcgagaa gttgcaggaa cgcctcctga
    27001 gactagcgta ttgtagtttt gatctttaaa gtctgcgatg tctaataatg tacctggtaa
    27061 gatatctgta tcacctggat ccattacacg aactttacgc agcatttgac gaaccattac
    27121 ttcgatatgc ttgtcgccga tttctacccc ttgcatacgg taaacacgtt gtacttcacg
    27181 aagcaagtag ttttcaacag ataatacatc gcgaacttgc aacaattgtt ttggatcgat
    27241 tgatccttct gtcaatggtg caccacggtg gatcatatcg ccttctgcta ctttcatacg
    27301 tgctgtataa ggaacagtat acgtacgtgt atctgttttt cctttgattg ttacttcttt
    27361 ggtacgtgtt gcaggatctt ctgagatatc gatgacatcc cctgttactt ctgtgatcac
    27421 tgcttgccct ttcggattac gtgcttcaaa gatttcttgg acacgaggaa gaccttgagt
    27481 gatatcgtct ccggcaaccc cacctgtatg gaatgtacgc atcgtcaact gagtaccagg
    27541 ttcaccgatt gattgagcgg cgatcgtacc aactgcttct ccgacttcaa cgtcagagcc
    27601 agttgcaagg ttgcgtccgt aacaatgttt gcagacacca tgttttgtat tacatgtgaa
    27661 gacagaacgg attgtcactg tttcgacacc tgcatcaacg atttgttttg cgatgtcttc
    27721 ggaaatcaat tggtttcctg caatgatcaa ttcatttgtt tcaggatgac gtacttcttt
    27781 acgggtgtaa cgtcccacta aacgatcttc taatgattcg atgatttcat ttccctcgcg
    27841 gatggcttgg atttcaagac ctcggtcagt accgcaatct tcttcacgga tgattacatc
    27901 ttgggccacg tcaaccagac gacgagtcaa gtaacctgaa tcggcagtct tcaaggctgt
    27961 atcggtcatc cctttacgag ccccgtgagt tgagataaac atttccaaga cggatagtcc
    28021 ttcacggaag ttcgaaatga ttggcaattc catgattcga ccattaggag cggccatcaa
    28081 accacgcatt ccggcaagct gtgtaaagtt ggaaatgtta ccacgagctc cagaatcaga
    28141 catcatgaag attggatttt tcgcttccaa accttccatc agtttttgtt ggatgctgtc
    28201 ttttgcagca ttccaaacag caatgacacg ttcataacgt tcgtcatctg tgatcagacc
    28261 acgacggaat tgttttgtaa tagtttcaac ttgtttatgg gcattttcaa tgatttcttg
    28321 tttttcattc agtacactga tgtcagcgat ccctactgtg ataccggcat gtgtcgaatg
    28381 tttgtaccct aagtctttca tacggtcaag catcttagaa gtttctgtta ctttgaatcg
    28441 tttgaagact tctgcgatga tgtttcctaa gtttttcttc ttgaacggta atactaattc
    28501 ttgctctttg atatgtgcag gaatatcagt accagcttca acaaagtatt tgtccggtgt
    28561 ttggacggtc aagttgaagt ctgttggttc attcagataa gggaattcag gaggcatgat
    28621 ctcgttgaag atgatcttac caactgttgt gatcatcgta cgttcttttt gccattcagt
    28681 aaatggtttt tcacctaatg agttagggtt cacaccgata cgtgaatgta aatgaacata
    28741 tccgttgcgc catgcgataa cggcttcgtt ttgatctctg aagaccattc cttcgccttc
    28801 gcgtccttct tcttccattg tcaagtagta gttacctaga accatatctt gagaaggagt
    28861 aacaactggt ttaccatctt tagggttcaa gatgttttga gcagctaaca tcaacatacg
    28921 tgcttctgct tgtgcttctt cattcaatgg aacgtggaca gccatttggt ctccatcgaa
    28981 atcggcatta taagcttcac atacaagtgg atgcaaacgg attgcgcgtc cttgtactaa
    29041 aactggttcg aatgcttgga taccaagtcg gtgaagcgta ggtgcccggt tcagcaatac
    29101 tgggtgttcc ttgattacgt cttctaaaac atcccatact tcgtcttctt gacgttcgat
    29161 tttacgtttc gcatttttga tgtttgaagc tagttcgcgt tgaacaagct cacgcatcac
    29221 gaatggtttg aataattcaa tggccatttc ttttggaagt ccacattggt acatcttcaa
    29281 gaaaggtcca acaacgataa cggaacgacc tgagtagtcg acacgtttac ctagcaagtt
    29341 ttgacggaaa cgaccttgtt tccctttcaa catatgagaa agagatttca atgggcggtt
    29401 acctggtcca gtaactggac gtccgcgacg accgttatcg atcaatgcat ctactgcttc
    29461 ttgcagcata cgtttttcat tttgaacgat gattccaggt gcattcaagt ctaacaaacg
    29521 tttcaaacgg ttattacggt tgattacacg acggtaaaga tcattcaagt cacttgttgc
    29581 aaaacgtcca ccttctaatt gaaccattgg gcgtaaatct ggtggaataa cagggataac
    29641 gtccataacc atccagcttg gttgatttcc tgaagcgcgg aatgcttcta aaatatccaa
    29701 acggcggatt gcacgtgtac gtttttgtcc ttgtgcagat ttcaattctt ctttcaattc
    29761 ggctgcttct gcatctagat caacattatc aagtaattgt ttaatcgctt ctgcacccat
    29821 agcagcttgg aattcttgtc catattgttc acgtttttcg cgatattcgc gttctgtcaa
    29881 caattgtttt ttctctaaat tcgtatttcc tggttcgatg actacatatg aagcaaaata
    29941 aatgatttct tccaaagcgc gtgggctcat gtctaataca agacccatac gtgaaggaat
    30001 ccctttaaag taccagatat gtgaaacagg agctgctaat tcaatatgtc ccatgcgttc
    30061 acggcgaact ttcgaacgag taacttccac tccgcatcga tcacaaacga ttcctttata
    30121 acggatacgt ttgtattttc cgcaggcaca ttcccagtct tttgtaggac caaaaatccg
    30181 ctcacagaac aacccttcac gttcaggttt taaggtacga tagttaatcg tctcaggttt
    30241 ttttacttca ccgtaagacc agcttctgat tttttcggga gaagccaaac ctatttgcat
    30301 actttcgaat ttatttacat cgatcaaaag gggttccctc catttcattt aatggcaaac
    30361 cgcaagacgg ctgatcttcg accgccttgc agctcataga ccggattagt ctaaattatc
    30421 ttctgcggtt tcaaagtttt ggatgacatc gtctttttca tcttccactt gttcagcagc
    30481 tttcttttct aattctttgg cagtttgctg ttcggcaaat tttgtcaaag catcaacagt
    30541 gatcaaatcg tcgtcttcat cgtccatgtc gcgaagttcg atctctgttt cttcgatatc
    30601 caagacacgc atgtccagac ctagtgattg caattctttc accaatacgc ggaatgattc
    30661 cggtacacct ggttttggaa ttggttcacc cttgacgatt gcttcgtatg ttttcacacg
    30721 tccgactacg tcatctgatt tgtatgtcaa gatttcttgt aaagtataag ccgcaccgta
    30781 agcttccagt gcccatactt ccatttcacc aaaacgttgt ccaccaaatt gagctttacc
    30841 tcccaatggt tgttgtgtaa ccaatgagta aggtccgatt gaacgtgcat gcaatttgtc
    30901 atcgaccatg tgagcaagtt tgatcatgta catcacaccg acagacacac gtccatcaaa
    30961 tggttcacct gtacgtccgt cgtacagaac agttttcgca tcgctggcca taccggcttc
    31021 acgaactgtt tcccatacgt cttcatcact tgcaccatca aatactggcg ttgctacgtg
    31081 gatacctaac tgacgtgcag ccatacccaa gtgtaattcc aatacttgcc cgatgttcat
    31141 acgtgaaggc acccctaaag gattcagcat gatatcgatt ggtgttccat caggtaggaa
    31201 tggcatatct tcttccggca taatacggga tacaacccct ttatttccgt gacgaccggc
    31261 cattttatcc ccttcatgga ttttacgttt ttgaacgata taaacacgaa ctaacatgtt
    31321 tacgcctggt gacaattcat ctccagcttc acgagtaaag attttcacat cgtgaacgat
    31381 accgccgccg ccatgtggta cacgtaatga tgtatcgcgg acttcacgag ctttttcgcc
    31441 aaagatcgca tgcaatagac gttcttctgc agataattct gttacccctt ttggcgtgac
    31501 tttccctaca agcaaatcgc catcttggac ttctgcacca atacggatga tacccatttc
    31561 gtctaaatct tttaatgcgt cttccccgac attagggatt tcgcgtgtga tttcttcagg
    31621 tcctaatttt gtatcgcggg cttctgattc atattcttca atatggatag aagtgtatac
    31681 gtcatctttt accaaacgac ggctcatgat gatcgcatct tcatagttgt acccttccca
    31741 agtcatgaaa ccaactaaaa cgttttggcc tagagccatt tcgccttgtt ccatagatgg
    31801 tccgtctgcc agagtatccc ctttttcgac tttctcaccc aaatgaacga ttggacgttg
    31861 gttgtagctt gttccggagt ttgaacgacg gaattttgtt acatcgtatt tatctaatgc
    31921 accgttgtcg cggcgtacgc ggatttcaga agcatcaacg tattcaacga caccgtcatg
    31981 tttacataac aaagcagctc ctgagtcatg cgctgatttg tattccatac cagtaccaac
    32041 ccatggtgct tgaggattga tcaacggcac tgcttgacgc tgcatgttgg cacccatcaa
    32101 ggcacggttg gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa cggcaactac
    32161 ttgtttaggt gatacgtcca tgtagtctac tttatcaata gatacttcta agttttcact
    32221 ttgagcacga gccataacaa cgtcttgagc aaatgttcca tcttcattca atgggctgtt
    32281 tgcttgggct acgatgtaat ggtcttcgat atcagctgtc aagtagtcga tttggtcagt
    32341 aacacgacct gtttcacggt ctacacgacg ataaggtgtt tcgataaatc cgaatttatt
    32401 tactttcgca taactggaca aactattgat caacccgatg tttgggcctt caggagtttc
    32461 gatcggacac atacggccat agtgggagta gtgaacgtca cgaacttcat aaccggcgcg
    32521 gtcacgagtc aatccgccag gtcctaaggc tgaaagacga cgtttgtgtg tcaattcgcc
    32581 aagagggttt gtttgatcca tgaactgtga caactgagaa gaaccaaaga attctttgat
    32641 acttgccaca actggacgga tattgatcaa ttgttgaggt gtcaatgttt cagtatcttg
    32701 gatcgacatt ctttcacgaa ccacacgttc catacgtgct agcccgatac ggaattggtt
    32761 ttgtaaaagt tcaccgactg aacggatacg acgatttcct aagtggtcga tatcatcgac
    32821 attgccgata ccttccatca agttcaagaa atagctcatt gaagcaatga tgtcggctgg
    32881 acgaaccgtt tttacagctg cttctggata gccgtttccg atcacgttta cttcacgttc
    32941 agggtctctt ggtgaaaata ctttgatgac ttggacagtc attggatctg tgaccacacc
    33001 gtcttctgat ggatagtaag tcactgaatt taggccatta tcaatgaaag gagctagtgt
    33061 ttccatgact tggtgagtca gaactgttcc tttttcaacg atgatctcgc ctgtttctgg
    33121 atcaactaat gtttcagcta atgtcagatt caatagacgt gttttcaaat ctaatttttt
    33181 gtttactttg taacgaccaa cgtttgctaa gtcgtaacgt tttggatcga agaaacgagc
    33241 attcagcaag ttacgtgagc tgtctgctgt ttttggttcg cctggacgca aacgttcgta
    33301 aacgtctttc aaaccttctt ctgttcttga gtcgcttgcg tttttatgca agtctttttc
    33361 gactgtattg cgtaatgttt cgctgtcgcc gaagatttca aagatcgtat catcggaacc
    33421 aaatcctaac gcacgaacta atacggttaa aggaatctta cgtgtacggt cgatacgtac
    33481 ataagagatg tcttttgcat cagtttccat ttctagccaa gctccacggt tagggataac
    33541 agtagaaccg aatccttctt ttccgttttt gtcgactttt ccatggaaat agacacctgg
    33601 tgaacggact aactgagaaa cgattactcg ctctgccccg ttgatgatga atgttccttg
    33661 ttctgtcatt aatgggaaat caccgaagaa tacttcttgt gctttgattt cgccagtctc
    33721 gcggtttgtc aaacgcaatg ttacatgtaa tggtgcagag tagtttgcat catgcgcacg
    33781 agcttctgct actgtatact ttggttcttt caattcataa tctacaaatt ccaaagatag
    33841 attgccattg aagtcatcga ttggcaaaat gtcttcaaac atttctctaa gtccctcatc
    33901 taagaaccat tggtaagagt ctgtttgaat ttcgatcaaa tttggtaatt ccaacacttc
    33961 actgattctt gcgaaacttc tacgttcgcg atgttttccg tattttacta cgtgtccagc
    34021 caagctcttc acccctctaa aatgtcattc aaaaagacta cccgatcaat tgttacaata
    34081 atatttcaaa tattattttt aggtaacaac agacattttt tgcggctttt aggcaaaaaa
    34141 aaaccaaaaa tagaacattc tcttgaaacc ttacttcgtg agcttctact tttgtttcct
    34201 tatattaaag ccgaaacgga caatatttcg tttctgcctt ttcttcatca gatagttttt
    34261 gcaacttcat atactacact tattttctat aaaagtcaac acttcctggc gtttcttctg
    34321 ctttttcgca acattttctt aatgttttca attttatgtt ttcaattatc tgacaattct
    34381 taattgacag acctttttat ctcggttata ctttagaaaa ttcattttgt ggaggaactt
    34441 ctatgcgaac caacatcaac caaatcgcac caacacaact gaataacttt tactttagct
    34501 actttagata ggtttgtatt catcatgatg gatacaaacg ttaaacgaca gtttgtatct
    34561 atgatggcta aagaactttg tattgcagca aaaagccacg tagacaaaat gctaagtggc
    34621 tgagcagtga aaatacaaag taaaagtatc aagcattcta ctttttcaat ttattttccg
    34681 acttttcaat ccatttggac attttgtctg aatggatttt ttgtttccca aaattaagga
    34741 ggaaaaagaa atgaaaaaaa atataatcat cggattaggc gctgccctgc tactagcttt
    34801 aggaggttgc gcacaaaaag acaattccgc agaggcatca gatggacaaa aaacaattgg
    34861 cgtattgcaa cttgtacaac ataactcgtt agatgctgcc tataaaggat tcaaagaagg
    34921 attagcagaa gaagggtata aagaaggcga taatctaaca atcgattatc aaaatgccca
    34981 aaacaatcaa gacaacctga aaagtatgag tgagaaactc gtcaaagaag atcctgattt
    35041 gctacttgga atcgccactc cagcagcaca atctttatta aatgaaacaa ccactatccc
    35101 gatgactgtc acagcggtca cagacttgga acaagcccat ttagtcacat ccaatgaaaa
    35161 acctggcggc aatgtgactg gcacgacaga tatggtgcca atcgaaaaac aaatcggctt
    35221 actgttaaat atcgtgccag acgccaaaac aatcggcatc atgtataaca acggtgaagc
    35281 aaactctaag atccaagctg atttggcaga aaaagaattg aaaaaagcgg gcgtcaaagt
    35341 caaagtactg acagcaaatt ccacaaatga tgtccaacaa gtgacgaaaa gtctagctaa
    35401 agatgtagat ggaatctata ttcctactga taacacgttc gcaagtgcgg caagtgttgt
    35461 cggtgaagtc gcaaaagaaa caaaaacacc tgtcgttgct ggcgcagttg atcaagtcaa
    35521 agacggcggt ctagcaacag taggaatcga ctacgaaagc ttgggcaaac aaacagggat
    35581 catggcagca aaaatcttag acggcaagaa tccaagtgaa cttcctgtcg aaacagcgaa
    35641 tgatttggaa ctgtatgtca ataaagacat ggccaaagca ttaggcatca atccagacag
    35701 catcaaagaa gctgaataaa acacaggagg attctcatga caaatttgct ctctcttttc
    35761 ttatcatctg catcgcaagg ggtcttatgg gccctacttg cgattggtgt atacgtcact
    35821 ttccgtatct tggacattgc cgacttgact gctgaaggaa gctttccttt aggtgcaggg
    35881 atcgcggcag taagtattac aaatggctat catccattga cagcttgtct tctaggcttt
    35941 ttagggggtg cggcagcagg gcttgtttcc ggactgcttc acacaaaatt gaaaattccc
    36001 gcccttcttg cagggatcat caccatgact ggtttatatt ctgtcacatc ccgtgtgatg
    36061 ggtgcgccga acatctcttt attgggtcag ccaacgatct ttcattgggt cgagtcattc
    36121 ggcataacaa aagacaacgc tgtactgatc gtcggtctgc tttttgcttt gatcgttgta
    36181 tgtttacttg ttttgttctt acgtacagaa acaggacttg ctattcgtgc aactggcgat
    36241 aatctggcaa tgagcgaagc aaacgggatc aacacagata atatgaagat catcggttat
    36301 atgatttcta atggatgcat tgctctttct ggctccttac ttgcgcaaaa caacggcttt
    36361 gctgatttaa attctggtat tggaacgatc gtaattggac ttgcttctat tatcatcgca
    36421 gaagttttgt tacgtaacca gccactattt ctccgtctct tgactgtcgt tttaggtgcg
    36481 gtcatttatc gttttatttt agcgttagtc ttcgaactga atgttgaacc aagtgattcg
    36541 aaacttgctt ctgctttcgt gctagtgatc tgtctttctt tcccgcagat ccagcaaaaa
    36601 ttccatttac ctcaaaaaaa gaaaggcggt agtgtcaaat gaatgacgtc ttaacattgg
    36661 aaaatctcca tcataccttt gaaaaaggaa cgatcaacga aaatcatgtc ctgaaaggca
    36721 ttaatctttc cttagatccc ggcgacttcg tgacgatcat cggtggaaat ggggctggta
    36781 aatctacttt gctgaacagc atcgccggta cattttctgt cgatcagggt caaattttat
    36841 tgaatggaaa aaatatcacg aaaaaatctg ttgtcgaacg ttcgaaatcc atcagtcgcg
    36901 tattccaaga tcctaaacta gggacagccg ttcgtttaac ggtagaagaa aatcttgctc
    36961 ttgctatgaa acgaggaaaa aaacgcggct tcttccgtgg tgtcaaacca caagaccgaa
    37021 catttttcaa agaccagctg gttcggctaa atttggggtt ggaaaatcgt ttatcctcag
    37081 aaatcggttt gctgtctgga ggacaacgtc aagctattac gttattgatg gccacattac
    37141 agcgtccaga actgatctta ttagatgaac acactgcagc gcttgaccct gctacttcca
    37201 aaacggtgat ggaattgaca gaaaagctga tcactgagca gaatctcact gcttttatgg
    37261 tcactcatga catggaagac gcgatccgct atgggagtcg actgatcatg ctgcatcaag
    37321 gaaggatcgt cgtagatatc cagcaagagg aaaaacagca gctcacagtg ccccaattat
    37381 tagcgttgtt caaacaaaac agcggcacgg cattaaaaga cgatcaagta cttttatctt
    37441 cataatcaga aagaggatgg gacaaaaaat gaacgcccac cctcttcttt tttctctttc
    37501 cttctttcgt ttttgcttta tgtatcaacc gttgtttctt cgaaaactat tttgttctct
    37561 ccttcttcct gatagaatgg atgggaaagg agcttgatgc catgacaacg aaagacaagg
    37621 tacttcaatt attgaaaaag acaccagatt ttctttccgg agaaaagttg gcacagcaac
    37681 tggaagtttc ccggacaagt atttggaaag ccatcaaaga attggaaaag gcaggctatc
    37741 gttttgagca cgggcctaca gggtatcgtt acctgccctc tgacgtacta gatgcaaaag
    37801 aaatccagca agagctacgg tcgtttattc ctgatttgaa agtacaaacg atgttgactt
    37861 ctgaatctac gatgaaagat gccaaactgg cagcagctca aggagattct gtttcgaagt
    37921 tatttgttgc tgatacacaa gaacaagctc gtggacgttt tggacggcct tttttcgctg
    37981 aacctggacg aggaatctac atgagtctct tgctccatcc agacaaacgg tttgatgaat
    38041 tgcctcaata tacgatcatc gcagccagtg cctgtgtgaa agccattgaa tctgtaaccg
    38101 gtcgttctgc ttcgatcaaa tgggtcaatg atatctacat ggatggaaaa aaagtctgtg
    38161 ggattttatc tgaagcagtc agtgatatgg aaagcggcag gatcagtcat atcatcattg
    38221 ggatcgggct taatttttct gttcctcaaa atcattttcc agctgatctc caagaaaaag
    38281 ccatctctgt ctttcccgac ggacaagcta gtgtcacaag gaatcagcta atcagcaaaa
    38341 tctggcaaga attgttcact tatctttctc acccagaaaa agcgttggac ttctataaag
    38401 aaaaatcatt cgtattggga aaaaccgtgt cgttcaatca aaaaggaacg acttatgtcg
    38461 gtcttgcaaa agaaatcggt gatcatggcg aactgatcgt ccaaacaaat gaacagaaga
    38521 tgagtttgtc ttctggcgaa atcagtctca catctatccg tacgcaataa ttatcagatt
    38581 tcacaaaagg acacctgatc tcatacagtg tccttttttc tgaattctct tcaaaagact
    38641 ctccttattc tatcagctga cagtttctct atcctctaga aaaaggtatt ctaaaaatat
    38701 ctataaagca tggtacactt tctttaaatg aatcaatgca aaaaacaaga gagtcatcag
    38761 tttacacgat caaaagagat agcaggccgc ttcctttttc aatcttatag atagaccatg
    38821 ggtaacgata aaaacaaaaa agaacttgcg acttattttg ccgtaagttc ttttttagct
    38881 agtgccttaa tctcttaatc ccaacaaacg tctcgcatag atcacctgac cagagtgcat
    38941 agcagcatca tcaataatag aaacgagacg cattcctcgt gtgactggtg gtgtccagtt
    39001 ctcgtcaatt acttcatcta gctcggaagg ttccagcctt cttaagtaag aaatagcaaa
    39061 atcagcagct cctcgcaagt atcctagcag atcttctatt tgattagctt ggatctgctt
    39121 tgcttgttcc agactatgct tccaatcttg ttcgttatct gctatcgtca tcggaaaccg
    39181 gctttcccag tcttgactat gccaaattgg agaagttcct gctaaatcag caatctggaa
    39241 atctaattct cgagcggtat gccaagccag ccaagtcatt gatttgatct gcggggctct
    39301 atcttccact ggaaaacgat tggcctcctc aatagagacg ccttcaaaca aacgttcaaa
    39361 ccgatcgtat gcccgatcca cactctcgca tagcatatct aaataatcca tttattttcc
    39421 tcctttttat ttatcctact tactttttcc taattctagg atacctactt atatgttact
    39481 acacaccctt attttttaca ctttaacagt caccatcatc aatagtttgg agattgaaag
    39541 aaaaagatag tgtcgaacta tcaattgaac aagaagcaac aatatgaacg tttcattaat
    39601 attctttaaa taaacaatga tttttcaaac gaacagttta agactaggag aaaaagagta
    39661 taataggaaa atgtttgaaa ggaaaggaag gggaaaaatg aaaaaaaggg caagtttact
    39721 agtcctagtt gctttgttgt tcaatatctt ttcgtatggt gtggccgttt cagcggaaac
    39781 atacattcct aaagaccctg ggaatattta taatgatcta actggtaact atggcttgtt
    39841 aggaattgct agtcaattcc acgtatttgc taaaaataag acaactgtga atgcacatac
    39901 agacggaaat atagcaacac atgaacttga tgcaaaaaat aattttggta cagagcttca
    39961 tgaaggttta ttgaaccaag aaataaatta tatacaaaaa actgattctt tcgctaattc
    40021 ttcaggcata cctacaggta gcacaagaat gaataaattt gtcgttggca gtaacgtgga
    40081 tgtagcactt caagatggtc atcctacagt caatggatcc aggcttgatc acttaactcc
    40141 agatgatttt tataaagatc gtgctgggca tgaatatatt gatttcgagc aggaatttgc
    40201 taaattgaat gtagcagcaa atgatcttgc aacgatcact ccagctaaaa catatactgc
    40261 tgcagatttt ccagacatga acaatcggac aatcgattta actgatttat cagataccgg
    40321 gtttttattg gtaaatatcg atgcagaagt gttaacgatg aatacgccac ttcaaatcat
    40381 taatccaaat gatcaagtag ttgtatttaa tgtcatcaac agttcttctg cattgaacgt
    40441 acagtcacca atcaaataca atgatcgttc aaatcatgaa acagaagatt tttcggatgc
    40501 gaatatctct tggaattttg gaaatgagat gactgatttg acaatcagtg ctccttttca
    40561 aggaacaatc cttgcgccta atgctactat ccgcattact caaaaccaag acggaacgat
    40621 tataggaaca aatgtgattt tagatgcagc taccaatcgt tgggatccta acgaaatatt
    40681 tatcagcgac aatggtacag atacgacaga cacaagcgac agtacagata catctaccac
    40741 aagtgatagc tcagattcat caacttcaag cgacagtaca gatactacct ctaccacaag
    40801 tgatagcacg gatacatcag cttcaagcga cagtacagat actacctc
//
LOCUS       DACGDM010000017        39953 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.017, whole genome shotgun sequence.
ACCESSION   DACGDM010000017 DACGDM010000000
VERSION     DACGDM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.017"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IXR05_000979"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IXR05_000979"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAQ4259517.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IXR05_000980"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IXR05_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAQ4259518.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IXR05_000981"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IXR05_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAQ4259519.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IXR05_000982"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IXR05_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAQ4259520.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IXR05_000983"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IXR05_000983"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAQ4259521.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IXR05_000984"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IXR05_000984"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAQ4259522.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="IXR05_000985"
     CDS             complement(8053..8523)
                     /locus_tag="IXR05_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAQ4259523.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="IXR05_000986"
     CDS             complement(8569..8994)
                     /locus_tag="IXR05_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAQ4259524.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="IXR05_000987"
     CDS             complement(9061..9330)
                     /locus_tag="IXR05_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAQ4259525.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="IXR05_000988"
     CDS             complement(9341..10936)
                     /locus_tag="IXR05_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4259526.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IXR05_000989"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IXR05_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAQ4259527.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="IXR05_000990"
     CDS             complement(14489..15049)
                     /locus_tag="IXR05_000990"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAQ4259528.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="IXR05_000991"
     CDS             15402..16376
                     /locus_tag="IXR05_000991"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4259529.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="IXR05_000992"
     CDS             16546..17946
                     /locus_tag="IXR05_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAQ4259530.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="IXR05_000993"
     CDS             complement(18024..18746)
                     /locus_tag="IXR05_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4259531.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="IXR05_000994"
     CDS             complement(18825..19331)
                     /locus_tag="IXR05_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4259532.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="IXR05_000995"
     CDS             19454..21253
                     /locus_tag="IXR05_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAQ4259533.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="IXR05_000996"
     CDS             complement(21321..22895)
                     /locus_tag="IXR05_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259534.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IXR05_000997"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IXR05_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAQ4259535.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IXR05_000998"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IXR05_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAQ4259536.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="IXR05_000999"
     CDS             complement(24672..25310)
                     /locus_tag="IXR05_000999"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAQ4259537.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="IXR05_001000"
     CDS             complement(25311..25961)
                     /locus_tag="IXR05_001000"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAQ4259538.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IXR05_001001"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IXR05_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAQ4259539.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IXR05_001002"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IXR05_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAQ4259540.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="IXR05_001003"
     CDS             complement(29104..29844)
                     /locus_tag="IXR05_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAQ4259541.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IXR05_001004"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IXR05_001004"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAQ4259542.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="IXR05_001005"
     CDS             complement(31215..32153)
                     /locus_tag="IXR05_001005"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAQ4259543.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="IXR05_001006"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="IXR05_001006"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4259544.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IXR05_001007"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IXR05_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAQ4259545.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="IXR05_001008"
     CDS             complement(35313..35618)
                     /locus_tag="IXR05_001008"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4259546.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IXR05_001009"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IXR05_001009"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAQ4259547.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36724..37008)
                     /locus_tag="IXR05_001010"
     CDS             complement(36724..37008)
                     /locus_tag="IXR05_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259548.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37026..37916)
                     /locus_tag="IXR05_001011"
     CDS             complement(37026..37916)
                     /locus_tag="IXR05_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAQ4259549.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37936..38154)
                     /locus_tag="IXR05_001012"
     CDS             complement(37936..38154)
                     /locus_tag="IXR05_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259550.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38124..39824)
                     /locus_tag="IXR05_001013"
     CDS             complement(38124..39824)
                     /locus_tag="IXR05_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAQ4259551.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
BASE COUNT        10807 a         8710 c         7253 g        13183 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gctttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc ccctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatggaat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttacact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggttgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatca cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaatcg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gtaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ctagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 catcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc tttttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc caattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgtttttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gacatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatacc gagaaaatgg tttttgaaca tcacttattc
    36601 aaaataaaaa aagattgtga cacgaatttt gtcacaacct ttaaatgtat tcctagagca
    36661 aagaagctaa gcgaagaaat ccaattctgt ttatttattg tatttctttg ttcagcatcc
    36721 ttgctaaaag cccatattgg acaaagtatt cactacaccc atgatctcat cttttcgaga
    36781 acgtgctttt tctgtcggat cttctacctc ttctgtgtca attcgaacaa taaatttccg
    36841 attcatcgtc acgtaagcac cgtcgttgat caaaataaac agttcgttct cattatagtc
    36901 tgcacaggca tctttccata cgtcaaagcc gtttttttca gaagggatat cccgtttaac
    36961 cacagttttt ccacttaatt cgtggaacgt tacgtcataa tatttcatta tctctacctc
    37021 tttcgtcatt caatattttg tacttgttct ctgatttttt ctaagatcgt cttagactgg
    37081 acgacttgat ttttaatttc gattgcattt gatttggaac cgatcgtgtt gatttcccga
    37141 ttcatttctt ggatcaggaa atctaattcc cgacctacag gacattgtgc ttcgataagt
    37201 tcatctagtt tttgtacatg gatcgccaga cgatccagtt cctcgtgaat atctccgcgt
    37261 tccaacaaga tggctagctc cgtcaacaac cgttgctcat cgactttcgc tccaagaaat
    37321 tcctccagct ttttttgata ccttatttga aattcctttt catagatttc tacaaaacta
    37381 tcgagttttt ttagtacttc tttgaattct tcagtattct ttttcaacac taaagctaaa
    37441 gcttgacctt ctttttctcg actcgcctca atagaatcaa gtgcgctttt caatgtatct
    37501 agagctaact gtgccaattc ttccatgctc tcttccggtt tttcttctac cgttacgaag
    37561 ttttcgtcca gcacgaagcg ttccgccatc cgactaattg acacttgatt ttgactaccg
    37621 tatcgttgtt gaattccgtc tgtcaattga gtgataagtg aatcaatcaa ttcccagttg
    37681 atgacgatct gtttttcgtt tttgccaata taagctagat tcacaaatac ttcgattcga
    37741 ccgcggctta actgctgttt aataagctga cgaaaatcgt tttcaacaaa gttcaggatt
    37801 ttaggacttc gtatttgaac atctagaaaa cgctggttga cactttttat ttcaatatct
    37861 aactgatacg cttttgtttc gcggatggct ttgccaaaac cagtcatact tttcattcga
    37921 cagggtcctt cctcattaca tattttctat tgctttttgc agttgttcaa actcttcgtt
    37981 cgtcaatgtc aggcctttcc ccattttttc atggtctggc gcccaatctc gaagatcgaa
    38041 ttttggcggg cgaccattcc agctgactag gttcagttct ttacgccacc ccttgttgtt
    38101 ttctgacaat atagcgattt cttctacgat ttcatatgaa aattcttgtg ccatggttgt
    38161 tcctccttga gataatataa atataggatc agtaatgtgt caactggttg cttaagcaat
    38221 tcatgctgca aacgatcctt gcgttttcct tgtagcagat aatcaaaata aacagttttc
    38281 gtgcgctcat tttgtatttt ttgctggtat tttcgatacc ttcgccattc ttcagtactt
    38341 aattgaccaa tttgtgccaa taaatcatcc ggcatacttt ttatatcttg ttggcagatc
    38401 atttgaatca tcatgtctac ttgatagatt tcattgggca gtaaaaaatg tttttttgct
    38461 aaaagttcta gcatcgccaa tccgcatgtc tctggtacga ccctgttctt atataaatta
    38521 cgcagttttt gccaaaattt tatgcttttg aaaaaagata attctaactg aatttctttt
    38581 gttaagtaag acaaaaatcc tcgccagtat gttcttgcag gtttaacaga atgaaatgta
    38641 taccagttcc catagtaata gcctaatcgt tttttcattt ccagatagcc taattgtaaa
    38701 tttaattggt tcctttggct atcaaaaagc agaaagctgc ctagtgtcca caatgtttga
    38761 catttccaat ggataaaaat gtctggcata cgaatttttt tcgctgggcc tggcccttgc
    38821 acatctacga caaatgcctc tgttgctcct ttgttaatcg caatatcaat aggtattttg
    38881 ttgcgatacc caccgtctgc atatttattt tttccgatct ttcgataagc catagcggga
    38941 taaaatgaag cagaggcgag tatccaatct ggtatttctt ctgtttttgt ctgttggata
    39001 tcagtcacta cttccgctag ttctggcagt ttagtagaca ccgtatataa acgtattttg
    39061 ggattatgtt tgagtaagga caaatccaaa ttgtctttga ccatcttttc caatggagca
    39121 gaagaaaccc cgccttcaat tagtgctgtt ttcgtcattt ggcgtctttc tcgatagaag
    39181 cgttcacgaa ggtcttcaac tgcagccatt tctggtaacg caagcacttg tcttgtcgac
    39241 agctttttcc ataaattcac agcttttttc atatctcctt gtaaaatcaa tgcgccgttc
    39301 aacgcaccta ccgaggtacc tgtgataatc tcaaagttga tatcatgttc cttcagcgcc
    39361 tgccacacac caatctgata agcaccgtgc gctcctcctc cacctaaaac aagtgctgta
    39421 tgatagacca gctttttatt taattgtgtg gttccttgat agccgttttt atgaaaaata
    39481 cgcaaccatt cttctgatag aggagattga aataaaaaac aacagttttc tttaataaaa
    39541 aaacgagcgc aagcttccat ataccgaaaa aattttttcc attcaaaagt ttcaccttca
    39601 atcaacagat tattaaaaat aacatctcct ctacttttag caatagtaaa atagacggta
    39661 tattttttcg atactgcttt aaaagcacat tgcttttttg cagaacgcca aaaagcgtct
    39721 ctactttctt gatgactttg aaaaaatgga aggggttgtt ttgcttgctg gataggcgaa
    39781 tacagcgaca ttttctgtga aaagtaaact ttttttatct ccatcgcgct ctcctttttc
    39841 ttcaagtata ccagtacgtc ataaaaaggt catgagtctc gtattcgact ttgtagattc
    39901 cataagaaaa caattcataa aacctccttt aaataaaaaa atacaaaaat cac
//
LOCUS       DACGDM010000018        37480 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.018, whole genome shotgun sequence.
ACCESSION   DACGDM010000018 DACGDM010000000
VERSION     DACGDM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.018"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..2119
                     /gene="acm"
                     /locus_tag="IXR05_001014"
     CDS             <1..2119
                     /gene="acm"
                     /locus_tag="IXR05_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAQ4259552.1"
                     /translation="NITSLIPVHVYADAGRDISSNVTSLTVDPTNITDGGNIKVKFSF
                     DEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTVRKDSAQVVFNEN
                     IKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTKPASGSSSSVFYY
                     KTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPSTFEINQIHLGEQK
                     VYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVSYKTIIENPEQIN
                     FENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIFKYINDTEIGIPN
                     VTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEAPNWIDFDPLSSN
                     ELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFKLFRASTNNWEPV
                     PDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVPSGYQKIENGLVV
                     TNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEVSEKDDWRYRFTN
                     LPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPGSHITPWKNFPEK
                     TEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKSILPKTSSKKSSF
                     AVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2391..2876)
                     /locus_tag="IXR05_001015"
     CDS             complement(2391..2876)
                     /locus_tag="IXR05_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAQ4259553.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            3356..3997
                     /locus_tag="IXR05_001016"
     CDS             3356..3997
                     /locus_tag="IXR05_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4259554.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            4016..4651
                     /locus_tag="IXR05_001017"
     CDS             4016..4651
                     /locus_tag="IXR05_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259555.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4669..5484
                     /locus_tag="IXR05_001018"
     CDS             4669..5484
                     /locus_tag="IXR05_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4259556.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5803..7239
                     /locus_tag="IXR05_001019"
     CDS             5803..7239
                     /locus_tag="IXR05_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4259557.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7428..9875
                     /locus_tag="IXR05_001020"
     CDS             7428..9875
                     /locus_tag="IXR05_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4259558.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10105..11172
                     /gene="rlmN"
                     /locus_tag="IXR05_001021"
     CDS             10105..11172
                     /gene="rlmN"
                     /locus_tag="IXR05_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAQ4259559.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11365..12468)
                     /locus_tag="IXR05_001022"
     CDS             complement(11365..12468)
                     /locus_tag="IXR05_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4259560.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13021..13569
                     /gene="aac(6')"
                     /locus_tag="IXR05_001023"
     CDS             13021..13569
                     /gene="aac(6')"
                     /locus_tag="IXR05_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4259561.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14115..15776
                     /locus_tag="IXR05_001024"
     CDS             14115..15776
                     /locus_tag="IXR05_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4259562.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(15846..16193)
                     /locus_tag="IXR05_001025"
     CDS             complement(15846..16193)
                     /locus_tag="IXR05_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAQ4259563.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16277..17218
                     /locus_tag="IXR05_001026"
     CDS             16277..17218
                     /locus_tag="IXR05_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259564.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17219..18262
                     /locus_tag="IXR05_001027"
     CDS             17219..18262
                     /locus_tag="IXR05_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259565.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18268..19338
                     /locus_tag="IXR05_001028"
     CDS             18268..19338
                     /locus_tag="IXR05_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259566.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19328..20281
                     /locus_tag="IXR05_001029"
     CDS             19328..20281
                     /locus_tag="IXR05_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4259567.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20293..21303
                     /locus_tag="IXR05_001030"
     CDS             20293..21303
                     /locus_tag="IXR05_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4259568.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21588..22409)
                     /locus_tag="IXR05_001031"
     CDS             complement(21588..22409)
                     /locus_tag="IXR05_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4259569.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22506..22784)
                     /locus_tag="IXR05_001032"
     CDS             complement(22506..22784)
                     /locus_tag="IXR05_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259570.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23052..25061
                     /gene="metG"
                     /locus_tag="IXR05_001033"
     CDS             23052..25061
                     /gene="metG"
                     /locus_tag="IXR05_001033"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAQ4259571.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25540..26127)
                     /locus_tag="IXR05_001034"
     CDS             complement(25540..26127)
                     /locus_tag="IXR05_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259572.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26302..27624
                     /locus_tag="IXR05_001035"
     CDS             26302..27624
                     /locus_tag="IXR05_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4259573.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            27779..28555
                     /locus_tag="IXR05_001036"
     CDS             27779..28555
                     /locus_tag="IXR05_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4259574.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28548..29117
                     /gene="rnmV"
                     /locus_tag="IXR05_001037"
     CDS             28548..29117
                     /gene="rnmV"
                     /locus_tag="IXR05_001037"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAQ4259575.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29110..29994
                     /gene="rsmA"
                     /locus_tag="IXR05_001038"
     CDS             29110..29994
                     /gene="rsmA"
                     /locus_tag="IXR05_001038"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAQ4259576.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30445..31074
                     /locus_tag="IXR05_001039"
     CDS             30445..31074
                     /locus_tag="IXR05_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259577.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31198..32307)
                     /gene="ugpC"
                     /locus_tag="IXR05_001040"
     CDS             complement(31198..32307)
                     /gene="ugpC"
                     /locus_tag="IXR05_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAQ4259578.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32516..32938
                     /gene="mgsA"
                     /locus_tag="IXR05_001041"
     CDS             32516..32938
                     /gene="mgsA"
                     /locus_tag="IXR05_001041"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAQ4259579.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33261..33797
                     /locus_tag="IXR05_001042"
     CDS             33261..33797
                     /locus_tag="IXR05_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4259580.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(33837..35600)
                     /locus_tag="IXR05_001043"
     CDS             complement(33837..35600)
                     /locus_tag="IXR05_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259581.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35603..37318)
                     /locus_tag="IXR05_001044"
     CDS             complement(35603..37318)
                     /locus_tag="IXR05_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259582.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT        12352 a         6634 c         7728 g        10766 t
ORIGIN      
        1 taatataaca tcactgattc ctgttcatgt ctatgcggat gcaggcagag atatcagcag
       61 taatgtcact tcgttgaccg tggacccaac gaatattaca gatggaggaa acataaaagt
      121 aaaattctcg tttgacgaaa aaaaacaaaa tatccaacca ggtgattatc tttggatcaa
      181 ttggccaagt gaaggaaata ttcgcggtga aggattccaa aaagaaatcc cattaatgat
      241 tgaaaataaa aatgttggaa ctttaacggt cagaaaagat tctgcgcagg ttgtgtttaa
      301 tgaaaatatt aaaaacctag actcagtaga aggttggggg caatttgaga tacaggccag
      361 aaacgtaacc gataccggtg aagaaaatac gggaccattc accgtgacga gcggtgataa
      421 aacagctact gtaaatgtga caaagccagc ttctggttct tcttctagcg ttttttatta
      481 taaaacagga gacatgctac ctgaagatac taagcacatt cgatggtttt tgaatattaa
      541 caataacggc acttatgttg aacaaccagt taaaatcagt gatgaaatcc aaagtggaca
      601 aagattagat ccaagtacgt ttgaaattaa tcaaatacac ttaggtgaac agaaggttta
      661 tagaggagaa gagggaatcc aacaattttt acaagatttc cccagcgcta catttaattt
      721 ttcagtaact gataattaca ttgaaataac tataccaaaa aactttgtca atcttaggaa
      781 aataatggtg agttataaga cgatcataga aaacccagaa caaataaatt ttgagaatca
      841 ttcggaagct tggtttaaag aatttaataa acctgctgtt gatggagaaa gtttcaatca
      901 tacagttaaa aatatttcag cttctggtgg agtcaacggt acagttagag gcgaattgaa
      961 gattttcaaa tatatcaatg acacagagat tggtatccca aatgtgactt tcgaattaag
     1021 acgagcagat gaacagccta ttcaaggaca gtctagtatc ctgttgactt cgaatgaaca
     1081 gggagaagct agtatcaaag gcctgcaagt aggagactat gttgtaaaag aaaaagaagc
     1141 acccaattgg attgattttg atccactaag ttcaaatgaa ctcaaattct ccataaacga
     1201 aaatgataca gagggagtca gtttacctat ttataacaag aaaaaggtta cgaacatcac
     1261 agcaactaaa atttggaacg gtggaaccac tccaagaccg agtatttatt ttaaattatt
     1321 cagagcaagt acaaacaatt gggaaccagt tcctgatgca gaaacaaaac gattagacaa
     1381 tggaataact tcagtgactt gggaagatat ccaacagtat gatgatagtg gaaacgaata
     1441 tacgtttaaa gtgcaagaag tagatcaaaa cggaaatgat tatgtccctt caggttatca
     1501 aaaaattgaa aacgggctag tcgttacaaa tgagaataaa gaagtcattt cagtctcagg
     1561 acaaaaaaca tgggaagaca atgagaacca agacggcaaa cgaccgacga cgatcacagt
     1621 aaatctatta gccgacggtc aaccgatcca acacaaagaa gtaagtgaaa aagatgattg
     1681 gcgctatcgt ttcacaaatc tgccaaaata cagagacggg caagaaatca tctatactgt
     1741 aacggaagac aacgtgcccg aatacagtac gacgattgac gggtataaca tcaaaaacag
     1801 ttatacaccg gaaaaaacaa atatatctat accaggtagc catataacac cgtggaaaaa
     1861 ttttccagag aagacagaga gagagaaaat tagaaatcta ttctctcaaa aattgcaaat
     1921 atttgctcat acaggagaat ccagcgaaca aagaagcaat tatattagta agagagctgt
     1981 acctaaacag ataacaaata aatcaaaaag cattcttcct aaaacaagta gtaaaaaatc
     2041 tagttttgct gtaatcattg gtttattgat agtaactatc tgtgctggga tattcttaca
     2101 aaaatataaa aaagtttagt tagaatataa tattttttgt taaatatgac tgaaatcaaa
     2161 agaataaaat tccgatttat aatcgaaaaa agaagcattt ttatatatgc ttcttttttc
     2221 gtagaatcaa taaatatgga tttggctaac tatggaagaa tactcgtatt agttttcagc
     2281 gttcatacta gttgttacat tgtttgattg gccaaaagaa tttctgatat attttgtgct
     2341 aaataaagaa aaagacgctt gaattgggaa ataagaaaac tactctatca ttacaaattt
     2401 tcataaactg gcagatgttc taagtaaaca agtatctttt caaagtcgga aaaatccata
     2461 atcaacgtag tggtattgat atttggatga aagcctacgg tatcttgacg atcaatagca
     2521 gcatcgatca cgacttggat ttttttctct ttgtcgtgca tcaatgctaa tggagtcact
     2581 gtacctgctg gaacgcctag gaggtcagga agctgttctt cagaaacaaa agataagcgc
     2641 ttttctttta attgttcagc tagttgtttt aaatcggcgt gcttttcatc aggcaagatg
     2701 acaagataga tttgttttcc ttttcttgat ttcaataata gattttttac ttgcggacca
     2761 ggtagggaaa aagggacatt tttgactgac gtaatcgcag gatgatcgac tttttgaaaa
     2821 gagataccca gtttttttag tagttcataa gcttcttgtt cggttgcacg actcatcgcg
     2881 catcaccctc ctttttttat tagtgtatca taaaaaagag ttgacaaatg aaaaataatc
     2941 atgtaaatta cacgtaaagt taaaacaaat gacatcgaaa agaagagtag ccgttaggtg
     3001 tttttagaga gtctctggtt ggtggaaaga ggcagcagtt aaccgtgaaa cacatcttgg
     3061 agtcgatttt ctgaagcgta tagtaggaaa atccggggag cccgttacag ctgcggtcgt
     3121 tgctagatga ccagataagg ctggcttttc cgtgaggagt cggtaaaaaa aggtggaacc
     3181 acgtgattaa cgtcctttga tcttcggatc aaaggacttt ttgttttcat ctgaacggca
     3241 acgactgtgt gaggtttttt ctgcaaggaa aaaataaaca gaggtggaac cacgtataat
     3301 acgtcctctt ggcatttgcc aagaggattt ttttatttta aaggaggaaa agaagatgga
     3361 gtatttgatt gaagttatgc cgcaattatt agtaggagca ctcacaacat tgaaattatt
     3421 tttatttacc ttgattggct cattaccatt agggattgtt ttagcattag gattgtcttt
     3481 gcattttaag ccgctacgct acttgcttca aacatatgta tgggttatgc ggggaacacc
     3541 gctgttgttg caactgattt ttatttttta tgggttgccg acgattggga tcgtttttga
     3601 tcgtttcgaa gcagcactca ttgcctttat cttaaactat gcagcttatt ttgcagagat
     3661 ctttcgtgga gggatacaat cgattcctca aggtcaatat gaagcagcgc aagttttgca
     3721 attaagtccc tttcaaacgg tgacgaaaat cgtcatccca caagtgacaa agattgtttt
     3781 accttctgta gggaatgaag ttatcaactt ggtcaaagat tcttccttga tctatatatt
     3841 aggtttaggt gacgtaatgc gtgctgggaa aatcgcgatg gaacgcgacg cgactttact
     3901 gcctttgcta ggcgtggcaa tcatctatct tacattgact ggtattctaa caatcataat
     3961 gaaacaagtt gaaggaaaat taaattatta ccgctaactg ataggaggaa gaaatatgat
     4021 tgaattgaag aaagtgaaca aagcatttgg tgaaaaaaaa ataatcaaag atttgaatct
     4081 aatcattcca gatgggaaaa cattagctat cgtaggtcct tccggtggcg gtaaaaccac
     4141 gcttttacgt atcttggctg gcttagaaag ttctgacagc ggagaatttt atttagacgg
     4201 tgtaccgttc aacccattcg agcttaaaat gaaagaacaa gttgtaggag tcgtattcca
     4261 agacttccag ctatttccac atctgaatat ttttgaaaac attaccttag caccaaaaat
     4321 ggtattgaaa cagacaaaag aagaatacac caaaaaagca gaagaattag cggcttcatt
     4381 agggattagt gatttattga atatctatcc ttatcagctt tctggcggac aaaaacagcg
     4441 ggtagcgatt gccagagcat tggctatgaa tccacgggta ttggcttatg atgaaccaac
     4501 aagtgcttta gatcctgaat tacgccagca agtcgagcgt ttgatcctat cattgaaaga
     4561 agatggggta acccaaatta ttgtcaccca tgatttagta tttgcagaaa atgtcggtga
     4621 tcaattacta aaagtttccc caattcatta agaaaggaga agatagagat gaaaaaaacc
     4681 agttttctat tcgctttgat cgcaggtctt cttctttttg caggctgttc gaacaaaaaa
     4741 acttcagcag ataattgggc gactatcaac gaagagaaaa aaatcgttat aggtttagac
     4801 gatacatttg ttcctatggg atttagagat aaagacggga agctcacagg atttgatatt
     4861 gatttagcca aagcagtctt tgaacaatat gggattacgg tagactttca gcccattgac
     4921 tggtcaatga aggaatttga actgaacaat ggaacgatcg atttgatatg gaacggctat
     4981 tccaaaacgc cggcaagaga aaagaaagtg caatttacaa aaccttatat ggaaaacgat
     5041 caagtgctga tcacacctaa agaatcagga atcacaaact ttggacaaat gaataataag
     5101 agattaggtg cgcaaaatgg gtcatctggt tatgatgtat ttacgaaaca accagaagta
     5161 ttaaaagaga tagtcaaaaa ccaagatgct gttttgtatg atagttttaa tgaagcattg
     5221 atcgatctga aaagcagacg ggtcgatggt ctgctgatgg ataaagtata cgcagactat
     5281 tatttgaaac aaagaaacga actagaagac ttcaacataa caaaaggttc ttatgagagt
     5341 gaggattttg cagttggtgc acgcaagtca gatagtacat tagtgaaaaa aatcaatgaa
     5401 gccctagatc aactagagaa aacaggtgaa ttccaaaaaa tatccgataa atggtttggc
     5461 gaagatgtta cgccgagaaa ttaacaaata ggggactgtg acaaaagacg tgtcacagtc
     5521 cctttttccg aataaacagt gttctcctgc caactccttg tgactcggag ctgaatggca
     5581 ggctcacaac ctcttggtaa acggtgttca aaagccagtt tttcggtatt aagccaaatt
     5641 tatgcaaaaa tgtagaaagc cattttcaca aaatttttct tactactcga aactaagcga
     5701 ctttttcaca acctccttta cataatttta ttttgttgtg gaaggggttt cgtgttattc
     5761 taaaagagga acgattgaag gttataggaa aggaagagat gaatggaaca caaagaactt
     5821 acctcatttc caaaagattt tctgtggggc tctgcttctg cagcgtatca agtagaagga
     5881 gcttggcaag aagatgggaa aggagaatca gtctgggatc gatttgtacg gatacctgga
     5941 aagacattta aaggaacgaa cggtgatttg gcagtagacc actatcatcg ttataaagaa
     6001 gatattgctt taatgaaaga acaaggtctg aaagcttacc gcttctctgt agcttggaca
     6061 cggatttttc ctaatggacg aggagaagtc aatcaagctg ggctcgcttt ttatgagaga
     6121 ttgatcgacg aattgattga aaacgatatt gaacctatgt tgactttata tcattgggat
     6181 cttccacaag cattgcaaga tgaatataat ggttgggaat cacgtcagat cattgaagat
     6241 ttcactcatt atgcagaaac attatttgag gcattccgcg ggaaagtcca ttactggatt
     6301 agtttgaatg aacaaaatat cttcacttca ttaggttatt tgttagcagc acatccgcca
     6361 ggtgtgacag acccgaaacg aatgtatgaa gttaaccata ttgctaattt agcaaatgca
     6421 tctgtcatca ataaatttca cgagttagaa atgcctggaa aaatcggacc aagctttgcg
     6481 tatacgccaa attatccaat tgacagtaat cctgaaaatg ttctggctgc tgaaaatgca
     6541 gaagacctga tggccaatta ttggatggat gtctatatgt ggggaaaata tccgattgct
     6601 gccatgaggt tcttagaaga aaaaggatgg gcaccaacga ttgaagctgg cgatgcagaa
     6661 ttgctagaat ctgctaaacc agattttctt gggatcaatt actatcaaac ggcgacgaat
     6721 gcattcaatc cattaaacgg agttggtgct ggaaaaatga atacgacagg aaaaaaaggt
     6781 tcatcagaag aaactggagt tcctggaatg tataaaaaag ttgagaatcc atttgtcgaa
     6841 cgaacaaatt gggactggga gattgaccca gaaggattaa ggatcggact gcgtcgtatc
     6901 acaagccgtt accgcatgcc ggtactgatt acggaaaatg gcttaggaga gtatgacaag
     6961 ttgacagaag ataaacaaat ccatgacgac tatcgaatca attacttaca aagccacgtc
     7021 aaagccatca aagaagcaat ttcggatgga gcagaagtcc taggctattg cacctggtct
     7081 tatacagatt tgcttagctg gctgaacggt tatcaaaagc gatatggatt tgtatatgtt
     7141 gatcaagacg aaacacaaga aggatctttg gaacgatata agaaagacag ttattactgg
     7201 taccaaaaac tgattgaaga aaatggagag aacctttagt tcacatactt aaaacaagaa
     7261 ggtacggctg gatatggccg tgccttttct tgataaaatc atttagaaat taagaaaaac
     7321 tgtaaaataa gctgaaaaat gaaagaaagc gtcagttctt tcaaacaaaa ctttagttcc
     7381 cttacttttt tttgtataat gaaacttgat gaaatgaggg ataataaatg gcacaaaaga
     7441 aacggcctac taaaaaaagg aaaaagacga aaaaaacgaa aaagcaaaaa cagcagcagg
     7501 aacaaatgct gacgattggt gttgggtttg ccttgatttt atttgctgtc ttcggctttt
     7561 taaaattagg ttttttagga atattgattg caaacggctt tcggatcatt gcaggaaata
     7621 cttaccaaat cctctgtctt ttattagccg tattaggatt ttggattgtc attaagaata
     7681 cagagttttc aattggtaaa aaccgacgct ggtttggcgg catactcttt tatttcggta
     7741 tcttattatt gttacatgcc catttatttg gcaaactcca tactggggaa ccaaatatca
     7801 tggggacgac atgggatttg ttagccagtg atataaaaca aagtcaagta gacaataacg
     7861 ttggtggtgg gatgattgga gcaatccttt atcattttac ttacttcttg attgcacagc
     7921 ctggaagtta tttagcagca gtgctattac tggcaggagg agcattcctg ttcagtaatc
     7981 tggaaggcta tcagctgtta aatggtatcc aatcaattgg agaacgagta caggaattat
     8041 tggaaggtga tcctgccaag caagctcgaa agcaagcggc aaaggaagag agaatgaaac
     8101 agcgcgcaga agcgaaagaa gcaaggcgct tagctgcaaa agaagctgca gaaaaagaag
     8161 ctgcagaata tgagaagaaa aaagcggtga gccagcaaag ggaaaatact gctgatgaat
     8221 ggcaggaacc agaaaataca gagccggagc agctaagttt tgttccaatc gacagttttc
     8281 aagaaaatat ccatcctgcg aatctagaga aaccagtacc agatacacca aaacagacca
     8341 atacagcaga aggtttttca gatgagttgc cagaggatga cggtacctca ttagaatttg
     8401 agattgaagc agaacaggaa aatcaagact atgaattacc gacagttgat ttgcttgatt
     8461 ctataccaac tgtggatcaa agtgatgagt ataaaaaaat tgaaaaaaat atcggcgtat
     8521 tagaacaaac tttccaaagt ttcggtgtcg atgccaaggt cgtcaaagcc agcttaggac
     8581 catccgtcac aaaattcgaa gtccagccgg ctgtaggggt aaaagtaagt aaaattgtga
     8641 acttaacaga tgatatcgcg cttgctttag cggcgaaaga tgtccggatg gaagcaccga
     8701 ttccaggtaa atcactgatt ggtattgaag taccaaatgg aaagatcagt atggtttcct
     8761 ttagagaaat catcgaagca caaccaaacc acccagataa attactagaa gtacctttag
     8821 gacgtgatgt ttctggacgg gtacaaacgg ctgatctttc gaagatgcct cacttactcg
     8881 tggctggttc gactggtagt gggaagtcag tagcaattaa tgggattatc acaagtatat
     8941 taatgcgtgc taagccccat gaagtaaaac tgatgatgat cgatccgaaa atggttgaat
     9001 tgaatatgta caacggcata cctcatctgt tgacgccggt cgtgacgaac cctagaaaag
     9061 cagcgcaagc cttacaaaaa gtagtacaag aaatggaaga acgatatgaa aaattcgcgg
     9121 caaccggagt aagaaatatt tctggttaca atgaatttgt tcaacagaaa aacttggaaa
     9181 acggaacgaa acatccaacc ttaccattca tcgtagtgat cgtagatgaa ttagctgatt
     9241 tgatgatggt agccagcaat gaagttgaag atgcgattat tcgtttagcg caaatggctc
     9301 gggcagcggg gattcatatg atcctagcta ctcaacgtcc aagtgtggat gttatcacag
     9361 gaatcatcaa agcaaatgta ccttccagaa tggcatttgc ggtatcaagc ggtacagatt
     9421 ctcggacgat cattgattct aatggggcag aaaagctctt agggcgagga gatatgctat
     9481 tcttgccaat gggtgagaat aaaccgatcc gtgtgcaagg agcattcatt tctgaccacg
     9541 aagtagaacg ggtcgttcaa tttgttacag atcagcaaga agctcattat gaagagaaaa
     9601 tgatgccgac agatgaagtt gaaacgacag gtgctccaga acagccacaa gatgagctgt
     9661 ttgaagaagc aaaagcactt gtcgttgaaa tgcaaacggc aagtatttcc cttctccaaa
     9721 gaagatttcg gatcggttac aaccgagcag cacgtttagt agatgaactg gaagctcatg
     9781 gagttgttgg cccgtcagaa ggaagcaagc ctcggaaagt attcattgag caggaagaaa
     9841 catcagaaac gttgccggac gataatgaca tgtaaaactt gtgtgatgaa gggttgaaaa
     9901 acgaataacc aataaaaaga caaggcatga tgataccaaa agaaaaaatg gtttttttcc
     9961 atcttttcta atacggtatg atgtcttgtc tttttagttt ttgtgagatt aaagttctat
    10021 tcgatttatt tgtgaagtat tgcattaagg aaatgaatca tgtatagtat gtagcgaaac
    10081 tttgagaaaa agagggaaaa tactttggaa aaacagtcca tttatggctt gacgaatgaa
    10141 gaattaatca attggtttat agaaaacggc gagaaaaaat tccgagctgc ccaagtttgg
    10201 gaatggttgt atcaaaaacg tgtaagtaat ttcacagaaa tgacgaatct atcgaaacaa
    10261 ttgatcgaaa aattatcgga gcattttatc atcaatcctc taaaacagat ggtcgtccaa
    10321 gaagcttcgg atggtacagt aaaatatttg tttgaactcc ctgataaaaa catgattgag
    10381 actgtactga tgagacaaga atatggcttg tcagtttgtg tgacgacaca agtaggatgt
    10441 aatatcggct gtacgttttg tgcaagcggg ctgctcaaaa agaaccgtga tctgactgct
    10501 ggagaaattg ttgcacagat catgatggtc caacattatt ttgatgagcg caatcttggc
    10561 gaacgcgttt cacatgtcgt tgtaatgggg atcggtgagc catttgataa ttacgacaat
    10621 gtaatggact ttttgcatat catcaatgat gccaaaggat tggcaattgg tgctcggcac
    10681 attacagttt ccactagtgg attagcacac aaaatcaagg aattcgctaa taacggcttg
    10741 caagtcaatc tggctatttc cttgcacgcg ccgaataatg aggtgcgaac atcgatcatg
    10801 cggatcaacc gaagtttccc aattgagaaa ttgatggaag ctgtggatga gtatttagag
    10861 aaaacaaacc gtcgaatcac gtttgaatat atcatgttga atcaagtaaa tgatagacca
    10921 gagcatgcgc aacaattagc agatctatta aaagataaga aaaaattagc atatgtcaac
    10981 ttgattccat ataatccagt cagtgaacat gatcaatatt ctcgcagtcc aaaagctgat
    11041 gtattgagat tttatgatgt attgaagaaa aacggcgtaa actgtgtgat acgtaaagaa
    11101 catggtacag atattgatgc agcttgcgga caattgcgaa gcaagcaaat gaaaaaaaca
    11161 gttgccaaat aatcgtatcc tactcgtttt ttcaattacc ataaaaggag cagttttctt
    11221 aattaaggaa ctgttcaact taaataagag aaaagattct atagcgaaag ctataaagct
    11281 ttttttgaca agaaaaaccc tcatcaagca aagaaatgtc ctcaatttga tgacagcctg
    11341 cttgatgggg gttttagcaa ttatttaact gattttctta tatccttgct ggctttcttg
    11401 tgtagcatga taagtttcta cgtcaagaat ggcctgttta aatttttctc gggtgatttc
    11461 ataaggcaca tgtttaatat catttgttgc catggcttta tctaagattg cttctaaatc
    11521 ggtcgtgaca ttgagattca tgtcggttaa cgatactgga agttggttct ttttcataaa
    11581 cacatagatt ttatcaaaca aatcgaactg ctgatccatc atcaataagg tcagtacacc
    11641 ataactgaca gatgctccgt gaaggtatcc ctccattttt tctagaacag tcgtaccgta
    11701 atagaatgag tgtgccatag cagaattata gttattgtta actaaaacag aaaccaatcc
    11761 ggtagtaaca atgatatccg aaacgacttg ttcaattgca tatgagggac gatcgtcggc
    11821 actatctttc aatgcttgcg taccataagt caagagacga tcaatgcaca tttttccgat
    11881 ttggattcct aatctatccg tgtagcctag atcatcgcca cgagcagaaa aagtagattc
    11941 gacttctttg gataaagcat cgccaatacc tgcccataag tatttatcag gtgcttcggc
    12001 aataattgct gtatcaatga aggtgtgtac aggtggtttt gaaggaaaga agagtccgtc
    12061 cattacgcct tcttcgttat agatgacaca taccgcagtg acgggcgaac agttcgaacc
    12121 aatagtggga aaggtgaaga ctggtttagc tagtttttca ccaatgactt ttacagtatc
    12181 gcaagcacgg ccaccaccga ctgcaaacag gacgtctgct ttttggacac tttcatgctg
    12241 gatcaactgt tcaatatttc cataagttga attacccccg taccagagac tggcgacaac
    12301 ctctatttcc tgtgtcaaag ctacttttat tttgttttct gcctttgaaa gtgcagtctt
    12361 ccctccaatc agcactactt ttgtcccata ttctttgacg attccatttg ctttttcata
    12421 cgcatctgtt ccaatggtat aatttggtaa gaaaacactt tgactcatat tcatttcctt
    12481 ctttcttcgt tgaaacgggt taaaatttta aagagtgatc gatctgactg cggctgtaga
    12541 tggagtagag gtgaacctaa gacaggataa gtgatgaata aggtggcatg aacaccttga
    12601 aatcatcaat aagtatccta aaaacgaaca agtacaaaaa cattgaaaac gacaataatg
    12661 aatttttgtt cctcttagta tttctaccga ttccctttgc ttttttgtaa ttatctaaaa
    12721 attctaaaaa ttaagattat tatatgaaaa caggttttat ttgtcaattc ataattggtt
    12781 ttttttaaag caaaagataa tctatatcat gatgaacaaa cagagttttt tcctccaatt
    12841 gatggctttc ctgatctttc ctattttgaa taaagtgttt ctgtataatt tttttatttt
    12901 ataagtaaga taaataatga aagaatagag atactgattg gtagctaaag atttttgagc
    12961 gagaacattt cgttttttca aaaggactgt tagaataagc aagaacaagg gggaagacgt
    13021 atgataatca gtgaatttga ccgtaataat ccagtattga aagatcagct ttctgattta
    13081 ctgagactga cttggccgga agaatatgga gacagctcgg cagaagaagt agaagaaatg
    13141 atgaatccag aacgaatcgc ggtagcagcg gtagaccaag atgagttagt aggatttatt
    13201 ggtgcaatcc ctcaatacgg tatcacaggt tgggaattgc atccattagt tgtagaaagc
    13261 tcccgacgaa agaaccaaat aggtactcga ttagtcaatt acttagaaaa agaagtagct
    13321 tccagaggag gaatcacgat ttatttaggt acggatgatt tagaccatgg aacaacgtta
    13381 agtcaaacgg acctgtatga gcatacattt gataaagtgg cttccatcca gaaccttcgt
    13441 gaacatccgt atgaattcta tgaaaaatta ggttataaaa tcgtaggtgt cttaccaaat
    13501 gcaaatggct gggacaaacc ggatatttgg atggcaaaaa cgattattcc tcgaccaaat
    13561 tctcaataat aaaaagaggt tgtgacagaa gtaatcagct tcaagaaata agaaggaatt
    13621 tacgaaaatt acttcttgaa tttttgtgaa attccaactt atttccgaag aagctacttt
    13681 tggaacaccg tgtaccagag gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat
    13741 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
    13801 tttgaacacc gtttattcag ataagggact gtgacaagac ttttgtcaca gtttcttttt
    13861 gtttattctt ttttatcttt gtatggcaat aatagacaat ataacgaaaa ttatttaatg
    13921 gcttttggaa gaccatggaa aaccttgtac aaagctattt tttctgaaaa attccttgaa
    13981 acctcacgaa aaaatcatta ttttatgaaa aagacaaaaa aaagtgttga ttttttaata
    14041 attattcatt aaactcttaa acaacttcag aaaatattaa ttattctgaa aattccaata
    14101 aaggggtacg taaaatgaaa aagaaattta catttggttt ggttgcggta tgcggccttg
    14161 tacttgctgg atgttatggc ggcagttcag ccacaagcag tagttcagca aaaagcggtt
    14221 cagcagatgg aggaggcgta tttaacttag tcgtgcctca agaaatgcct acagctgact
    14281 tatcagttgc aacagataca atcagtttta cagcattgaa taacgtttat gaaggaattt
    14341 accgtcttga tgaagacagc aaaccacagc cggcaggagc tagcgagttg gcagaagtca
    14401 gtgaagacgg attaacttac aaaatcaaat tacgagaaga cgcaaaatgg tcaaatggtg
    14461 atcctgttac agcagcggat tacgtttatg gctggcaacg aacagtagac ccagctacag
    14521 cttctgaata tgcttacctg tatgcgccag ttgaaaatgc agaagacatt acagctggaa
    14581 agaaagataa atcagaacta gggatcaaag cagttggtga ctatgaatta gaaatcaaat
    14641 tgacgaaaca aacaccatat ttccaatatc tgcttgcttt cccatcattt ttcccacaaa
    14701 aacaatccgt agtggaagaa aatggggatg cctatgcatc tgcaagtgat aaagctgttt
    14761 ataatggacc attcacatta gaagattttg atggaccagg aacagataca gaatggactt
    14821 ataagaaaaa tgatcattac tgggacaaag atacagtaaa actttctgaa atcaaagtca
    14881 gtgtagtaaa agaatcttct actgcattga acttattcaa agatggccaa gcagatgacg
    14941 tgatcttgtc tggtgagtta gcacagcaaa acgcaaacga tccagcttat acttctgtta
    15001 aagaagcgcg gacaagctat atcgaattca atcaacgtga aaagaattca ccattcaaca
    15061 atgtgaacct aagaaaagct atttcttatt ctatcgatcg tgaagcttta gtaaaacaag
    15121 tactaggtga cggatcagtt gtctctacag gattgatccc atcagatatg gtaaaaagtc
    15181 caacaacgaa cgaagacttt gcaaaagaag ctggaaaatt agtttcttat gacaaagata
    15241 aagcaaaaga atattgggaa aaagcgaaaa aagaattggg cgttgattct ttagaatttg
    15301 atttgatggc ttctgatgat gattcatcga aaaaagtaat cgaatatgtt caaaactcaa
    15361 tccaagaaaa cttggatggc gtaacagtca aaccaacacc tgttccattc tctgtacgtc
    15421 ttgaccgctc aacttcgggt gattttgacg cagtactagg cggatgggct gctgactatg
    15481 cagacccaag cagctttact gatttgtttg tcacaggtaa ttcatacaac cgtggtcgct
    15541 ggagcaatgc agaatatgac gaagcagtta aagcagcttc atcaacagac gctggcgatg
    15601 aacaagcccg ttgggatgat ttccaaaaag caatcaagat catctctgat gatatgggtg
    15661 tcgttccggt gtaccaaaaa gcagaaggtc acctagtgaa tgaaaaaatc aaaggtatcg
    15721 ttcaccatgc ggcaggcgct tcatgggatt acaaatggac atacgttgaa gaataatcgt
    15781 taataccgtg agcatgagaa aaaacgaggc tgcggcaaat gtcgcaacct cgttctcata
    15841 ttcacttatc ctaacaaaga aaaaagcatg aaaatagcag aaagagcaat tagtattccg
    15901 gcaatgatca gccaaaagct gtacataccg tagctggcag acgagagcga ggaaaattct
    15961 ggttttttct ttcggttcct tgttcgtgca agatggaccg atcgctgaaa atgatcgaag
    16021 aaacccgaag aaaagaccca taaaaaaccg ccgataatca gaaacggcaa tgaccataag
    16081 aatagatcat tagataattg aatgagtgta aaggaatggt tgatgagatt ttttattaaa
    16141 ataaccagaa tcagtagaaa agctactgcg taggggatag attttttttt catttgattg
    16201 ctcctttatt tttggttcat tatctaataa tgtagcgaaa catctgtcag aagtcaaaag
    16261 ctagggggaa acattagtga atagttatat caaatatgta ttaaaacgtg tctttttcat
    16321 gatcatcacg ctttggttaa ttgcaacaat cacctttttc ttgatgcaat tgctgccggg
    16381 cacgccatat acgaatcagg aacgtttgag tcctgaaaca atcgagatgc taaataaaca
    16441 agtcggtttg gataaaccag ttatcgtaca atatgggatt tatctttcta atttgcttca
    16501 aggagatttt ggaatttcct tccaatttaa aaaccagcca gtcgcacatt tgttagctgg
    16561 aagaatcgga ccatccttgc agttagggtt acaggcaatt atctttggaa cagtcctagg
    16621 gacgatttta ggaacgatct ctgccatgaa gcaaaataca tgggcagata catcttctac
    16681 actcgtagcg atattaggtc gttccattcc aaactttgta tttgctgttt tattacaata
    16741 tatctttgca atcaaattac aagttttgcc aatcgcaaaa tgggatggct ttgtgtacac
    16801 aatcttacca acaattgcgt tggccatgtc gccgcttgct gactctgctc ggtttatccg
    16861 tacggaaatg gtggaagtac tgcatagtga ttatgtggaa ttagcaaaag caaaaggatt
    16921 gagccgttgg gaaatcgcct ttaaacatgg tcttcgaaat agtttgattc cattgatgac
    16981 tttattagga ccgttagctg tagcattgat gaccggatca ctggtggtag aaaatatctt
    17041 tgctattcct ggtatcgggg aacaattcgt taagtcaatc acaacaaatg attatcctac
    17101 gatcatggct gtaacgatcc tttactcatt tatgctgatt tttgttattt tgatcgtgga
    17161 tctattgtac ggtctagttg atccaagaat tcgtgtttca gaagggagcc gaggataaat
    17221 ggaaatgata ccaaagcgtt atgaaacagt tgcagatatc cctgcggatg aatttcttcc
    17281 attacaaaaa aataccgaag aagaacgtga acagattact gcaccttctt tgaattttat
    17341 ccaagattca tggcgccgtt taaagaaaaa caaagctgcc gttatttcaa tggttttact
    17401 attggtcatc attttgatct ctgtgatcac aatctttgtt tctcctcatg atccaactgc
    17461 ccaaaacgtg gcttatatca atttgcctcc tcgtattccg ggaatcaata tcgatggatt
    17521 gaatggaaaa gcaatggttg gtggtgaact tgttgataaa tatgctcaag caaacgtccc
    17581 ttcaaacgta aatttctttt taggaacaga cggtttggga cgtgatgtat taagccgctt
    17641 atttatggga atgagaatct cgttgctgat cgcatttatt gctgcattac tagatgtaac
    17701 gattggtgta gcttacgggt tggtttctgg tttgttaggc ggacgtgtcg ataacgtgat
    17761 gcaacgtttt ttggaaatct tatcaggaat tccaaacctc gttgtcatga ttttgatgtt
    17821 ggtcgttttt gaaccaggaa ttttttcaat cgtggctgct atggccatca caaactggat
    17881 accaatggca cgtatcgttc gtgcacaaac aatgaaatta aaagatcaag aatatgtttt
    17941 agctggattg acattaggtg aatcaagaat gaaaattgca ttcaaacata ttttgccgaa
    18001 tatctctagt gtcattatta ttcaaatgat gtttagtatt ccatctgcta ttttcttcga
    18061 agccttttta agctttatcg gtttaggtct tacgcctccg tcagcttcat taggaacgat
    18121 gttgagcgaa gggtacaaga cattcctgta tctgccttat ctattatgga ttccggcagt
    18181 aactttatcg gttatcatga ttggctttaa cttacttgct gatggattgc gtgatgcctt
    18241 tgatcctaaa atgaaagagt gaagacgatg acgaaaattt tagaagtgaa agacttagaa
    18301 atctcttttg atacgtatgc tggaaaggta cgagcgattc gcggtgtcaa ttttcatttg
    18361 aataaaggag aaacattggc gatcgttggg gaatctggaa gtggaaaatc agtgacgacc
    18421 agaagcatca tgcgcttgct gtcaagcaac gccaatatag atgctggtca aatcctcttt
    18481 aaaggtaacg atatcgttgg aaaatcagaa agagagatgc aaaaaatccg tggtaaagaa
    18541 atagcgatga ttttccaaga tccaatgacc tctttagatc cgacgatgcc cattgggaag
    18601 caagtcgctg agtcccttag aaagcataat aaagtttcaa aaaaagaggg acaaaaagct
    18661 gcattagaat tgcttaaatt agttggaata cccgaagctg agaaacgtat caacagttat
    18721 ccgcatcagt tctcaggagg tcagcgtcaa cggatcgtga tcgcgattgc actggtatgt
    18781 tatccggaaa tcctgattgc tgatgaacct acaacagcgc ttgatgtgac tattcaagca
    18841 cagattttgg agctgctgaa agaaattcag acaaaaatcg atacatcaat tatctttatc
    18901 actcatgacc ttggtgtagt agcgaatgtc gctgatcgtg tcgctgtcat gtatggagga
    18961 agaatcgttg aagttggaac atcggaagaa attttctaca acccgcaaca tccctatact
    19021 tggggactgc ttggttcaat gccgacatta gatagtgcga acgatcgatt gtatgctatt
    19081 cctggttctc caccggattt attgaacccg ccaaaaggag acgcattcta tccaagaaat
    19141 gaattcgcga tgaaaatcga tgcagaacaa gaaccaccat tttttgaact atcaaaaaca
    19201 cacaaggcag caacttggct acttgctccg caggcaccca aagtgacacc gccagaagaa
    19261 atccaacgtc gctgggctat ctttaaagag aaacaaaaac atacttacgg tcaaggagga
    19321 attgctgatg ccaaataaac tacttgaagt taaaggattg aaacagtatt tcaatgtagg
    19381 aaaaaagaat gaagtacatg ctgtaaatga catcagcttt cacatttatg aaggagaaac
    19441 attcggttta gttggagaat ctggaagcgg aaaatccact actggccgta cgatcattcg
    19501 cttgaatgaa cctactgatg gtgagatatt attcgacggt caagatataa cgaagatcaa
    19561 agataaaaaa ggtttgacga aattccggca tgatgttcag atgatctttc aagatccata
    19621 cgcttcgttg aatcctcgta tgaaagtcag agatatcatt gccgaaggaa ttgatgttaa
    19681 tggactagct aaatcatctg aagagcgtgc aaaaaaagtc gatgatctat tgagaactgt
    19741 tggattgaat ccaagccacg gtactcgtta tcctcatgaa ttttcaggtg ggcaacgcca
    19801 gcgtattggt attgcacgag cattggcagt aaaaccgcgt tttatcattt gtgatgaacc
    19861 aatttctgca ctagatgtgt cgatccaagc ccaagtggtc aatttgttgc aagatctcca
    19921 aaaagaacat caattgacct atctatttat tgcacatgat ttgtcgatgg ttaaacatat
    19981 tagtgaccga atcggtgtaa tgcataacgg cttgttatta gagatgggaa caagtgatga
    20041 aatctataat cacggtgttc atccttatac agaaagtttg ttatctgcta ttcctctacc
    20101 agatccagac catgagagaa aacgcagaag aatcaaatat caacctgaac cagatgacgg
    20161 acaagtacgt caacttcgtg aaatcgcacc agaacatttt gtctatgcaa ctgagcagga
    20221 agtcccatat tacgcaaaaa aactaaaacg acaaaaggaa tctcttctgg ttgctaacta
    20281 ggagggacat agatgctaaa agcttttaaa ttccgtatgt atccgacaga agaacaaaaa
    20341 cagcaattga ttcgtacttt tggatgtgct cgatttacct ataaccattt gctgaaaaag
    20401 cggcagaaaa gttggcaaca aacaggagta gccaattttt cgctcacacc cgctacatta
    20461 aaaaaagaat acccattctt aaaagaagta gacagtcttg ctttagcaaa tgcacagctt
    20521 aatttggatc gggcttttcg caattatttc aagggacgtg ccagcttccc aaagcttaaa
    20581 acgaaaaaaa gtatgtggca atcttatacg accaacaacc aaacccgtac gatctatctg
    20641 gaaaatggct acttaaagtt accaaaacaa aaagaactaa tcaagataaa tcagcatcgg
    20701 ccagttgaag gatcgattcg ctccgctacg atttctgctc gatataatga agaattttat
    20761 gtcgcactac tttgtgatgt ttcgccagta aaaaaagaat ctttagctaa atggatcggg
    20821 atcgcctatc atccgaagac attgatccaa acatctcgac ctctagaagt aactttacca
    20881 aaatttcacc agacagaaga aaagctgcaa catgcacagc ggaaattgaa tgtgaaagtc
    20941 cgctccgctc accatagaaa gatcaggtta gatcaggcaa gcaattatca gaaacaaaag
    21001 agaaaagtaa tggatcttta tctgaaacaa aagaaccagc gagaagatta tcttgaacaa
    21061 ttatctggga aattggtcaa acaatatgac tacttatttg tagaatcttt tccaaaagaa
    21121 gaggcacatg ctgatttttc tattcacgac tggcataaat taataacaaa attgcgttat
    21181 aagtcccaat ggtataataa aaaatttctt ttgatcaata ccgacggagc agaagaaagc
    21241 aattccgtaa gaaagagcca agtagtagaa aaaatgggca gacattcggt tatcaaggga
    21301 taaaaaatga atgaaactga taggagcgtt agggttagcc ttgttaataa aaagtcttaa
    21361 tgacttttgt ttctaggaat ttttcttttg aagaaaagct cactaattat gacaaaccaa
    21421 taaaacaata gcagaaaaag ttcgtacgag ctttttctgc tattgttaat tttttattca
    21481 gaaagtttac gaatacatca aaattctgaa acaaaaaacg taactcacaa agagttgttt
    21541 ttgcgttttt tcttgaatga ttaggtctga atcttttgct cacaacctta ttcatggtgc
    21601 cccggcttga gctgatagat ttttgaagga cggccgattc ctacaggacg ttcaccgatc
    21661 tcatcgaaat attggagcat agctttctta aaattggaat gatcgatcgt tttataatcg
    21721 atccctaaga atttagcaaa tacttttcga gcttccgtaa tcgtgaaatc tttacctaaa
    21781 acttgtagaa cttgcggctc gtgttccatt ttattgacta cacggttgaa tgctttcaag
    21841 atgatttgac tatggtcaaa agccaaagta tctttgccag aagactctcc agtgactaaa
    21901 tcaagcgaga tagccacttc tccgctagat aaatggatct tgttactatg acgttctagt
    21961 gtgaaccagc gtacttcctt ggcatcatct ccggcgatta gcggttcttc tccaataaag
    22021 gctaagtagc tgactgtgac gacccagcct cgcggatctc gattaggcgt actgaatgta
    22081 tgcagttgct caatattttc ttttgaaata accacaccag tttcttcctt tgtttctctt
    22141 aagacgcttt ctccagttga ctcatccttt tggacaaagc caccaggcaa tgcccatgaa
    22201 tttcgataag gatgcccttt tctttggatc aacaaaactt tcagctgatc ttcttctttg
    22261 ttatagcaca tcagtacgat atcgacagtc aaagagggct tgtcatattc tggacgttcc
    22321 tgtttttgat accagttaag aaattcttct tcacttgctt tatgttcata atataatttt
    22381 tcttcttctt tagaagcaaa acggttcatc tgaccacctc cattgacagt aaaagtactt
    22441 tttaccttat tgtagcagac tctgaaaaaa aaccaaggat ttacttgaaa aatctaggtt
    22501 atcatttaaa tatgaaaaat aaatggaagt atgagattga ataaaaagaa aagcagataa
    22561 aacggcaata ctttataccg ctcttcacga atggcaaaga agccacaaat aacgatatat
    22621 acgtcaatga taaaacgcaa aatccaagct gctgtcataa aactgttcaa atgcccatgg
    22681 aggttaaaat aaccatacat acgaatataa aaatagctga atattaaatg tgctaatgaa
    22741 agaaaagcaa tactaagtgt aaaaaaaaga tgtttcttct gcatgattgt tccagtccct
    22801 tactaagata gatagtcttt attataccac gtgtgagggg agaaataaaa agccgttttt
    22861 tagtagatat gaaacaaaac aaaaacccgc atttattcaa cctattcatc cttttaaagg
    22921 atagattgaa cgtagataga agtcgtttat ccagtctttt tcattttgaa aaaaagctaa
    22981 cagcatgctt tttttatggt atactagcaa ggaaacgaat tcgcatcatg cgataaagga
    23041 ggaagagccc cgtggcagaa aaggaaactt tttatatcac tacgccaatc tattatccaa
    23101 gcggcaaact tcatatcggc aactcgtata ctacgattgc atgtgacgca attgctcgtt
    23161 ataaacggtt gatgggcttt gatgtgtttt atctcactgg agtggatgaa catggtcaaa
    23221 aaatcgaaac aaaagcagaa gaactaggtg taaaaccgca agaatatgta gataaaatgg
    23281 cggctgatgt caagaaatta tggaaaacgc ttgatatcag ttatgataaa ttcattcgca
    23341 cgacagatga ttaccataaa gcagctgttc aaaaaatatt tgatcgttta ttagaacagg
    23401 gagatattta cttaggtgaa tatgaaggct ggtactctgt ttctgacgaa gaattcttta
    23461 cagaaacaca acttgcagaa gtgtacaaag atgacgaagg taacgtgatc ggtggtaaag
    23521 cgccaagtgg acacgaagta gaattggtaa aagaagaatc atacttcttc cgcatgagca
    23581 aatacgcaga ccgtctattg gaatactatg aagaacatcc cgaattcatc cagccagaat
    23641 ctcgtaaaaa cgaaatgatc aacaacttta tcaaaccagg attagaggat cttgcagttt
    23701 cacgaacaac ttttacttgg ggagtaccag tcaagagtga tccgaaacat gtggtgtatg
    23761 tatggatcga tgcattatcc aattatatta ctgcactagg atatggctcc gaagatgaaa
    23821 gtctattcga aaaatactgg cctgcagatg ttcagatggt cggtaaagaa atcgttcgct
    23881 ttcatacgat ctattggcca atcatgctga tggcccttga tttgcctcta cctaaaaaag
    23941 tatttgggca tggctggcta ttgatgaaag acggaaaaat gtctaaatca aaaggaaatg
    24001 tcgtttatcc tgaaatgctt gtggaacgtt atggtttaga tgcactccgt tattatttgc
    24061 ttcgtgctgt tccgtttggg tcagatggtg tctttacgcc agaagatttt gtttcccgtg
    24121 tcaattatga tctggcaaat gatctaggga acttattgaa tcgaacgatt gctatgatca
    24181 acaaatattg tgatggactc gttcctgact atgcctcact tgtcactcca tttgatagtg
    24241 aactgtctac gacggctgct aacgttgtcg gacgttacca tgatgcaatg gaaaaaatgg
    24301 aattcaatac agcattggct gaaatctggg tgctgatttc tcgtgcaaac aaatacattg
    24361 atgaaacaga accatgggta ttagcaaaag acgaagaaaa gaaagctgaa ttgaatagtg
    24421 tcatgatcca tttagctgaa tctttgcgta tcgcagcgat attacttcag ccaatcatga
    24481 cagaaacgcc agagaagatc ttcaatcaac taggattgga ctctgaaaca atgaatcttg
    24541 aaggattaca ctttggcgaa tttccttcag gaacaaaagt agttgcaaaa ggtacaccaa
    24601 tcttcccacg tttagatatg gaagaagaag ttgcttttat tcaagaaaaa atgtctgaag
    24661 gtactcaaac aaacgaagat acagtcaaat gggatccaga agaaacagaa cttgtttcaa
    24721 cgaaagaaaa acaaatcaaa tttgatgtat ttgaaaaagt agaactaaaa gtagcagaag
    24781 tcatcaactg tcaaaaagta gaaggggcag ataagttgct gcaattccga ctagatgctg
    24841 gagacagcca agaccgtcaa atcttgtcag gaatcgctga attttatcct gatccaagcg
    24901 aattgatcgg gaaaaaagtc gtcattgtag caaatctgaa accacgaaag atgcgtggac
    24961 aaatcagtca aggaatgatc ctttctgcag aagcaccaga tggctcttta caagtaatcg
    25021 aagcaccaaa atccatgcca aatggctcag aaatcgcata gaaattcaaa gggggtatga
    25081 cactagttgt gtcatacccc ctttttccga aatttgagaa gcaattttcg taaattcctt
    25141 cttattactt gaagccaatc atataataca gaaacagaga actatccaaa ataaatccta
    25201 gaaaaagaag tacgagcttc gctgattttt gttaatttag aataatacta ataggaatcg
    25261 taaaaacaga aaaaaagcat aatgataaag ggtcgggcag attttaattg attcatctgg
    25321 tactcttttt tattgtcctt acattcataa agtttgaatg caatgacttt attacatcta
    25381 tatttatatc taacagtagc gttgatgtgt taattataag ttctatcact ttatgttcaa
    25441 ttagtttgtg ctcttatatg tgtgattgaa aatatagata aaaaaacaat catcggcttt
    25501 gacttcgatg attgttttct ttattttgta aaaatcctat cacttgattt tatggtaacc
    25561 ttttattttt gtcttcaaac ggcttggtaa gagagcagta agcagtgcaa atgggatcga
    25621 aaagacatac cagaaaatcg tacgtccgat accataatgt tgatagagct ttgtcaacat
    25681 cacgtgtaac aagatcaacc ctaaaagcaa ggagccagct ataaaccaat gattatccca
    25741 atgcatgact tcactaagtg ccatcactcc aaaaggatag aaataaaaat agatcccgac
    25801 taaggtcatc cgccagttct ttgtaaatgt tccgatattc aataaaaaga aaatcgctga
    25861 aagcaaaata ccgataggcg gaaaaagccc aaccaaaaag gaatacaaca tcccccacaa
    25921 gatcatcaca ggacctttga tcaatgcaac gattgcgatg aacaaagtca gcaatattag
    25981 tttttgtgat aacgttgcaa cagtcattaa tccaaataaa attaatgtga accaatgcca
    26041 atgggactgc tgttgttctt tacgggaaaa atcgacccgg ttggataaat aatctgctaa
    26101 tttcggataa gaacgcttaa aatccataaa ctgttcctcc ttcgtggaaa aggtaggttt
    26161 agtatacgaa aaataaaaaa gaaatacatc cgtcttaaga gggagttttt cactgaaagt
    26221 ggagaaaaaa gaatggtaaa ttaaaatatt ctcagttata ctgaaaatta taccaaattt
    26281 caaagaagaa agaggatggg aatgaaaggc aaactaaaac gagaaatcaa tctgtttggc
    26341 gcattagcta ccgttatggg aaccgtgatc ggtgcaggcg tcttcttcaa aactgctgct
    26401 gttactgcta gtactcagtc tacaagtttg acattgctag cttggctttt gggtggtttc
    26461 ttaacgatct gtgctggatt gacagtggct gaattagcta cagcaatccc ggaaactggt
    26521 ggagctgtaa aatatattga agctgcgtat ggaaaattgc ccagcttttt attaggatgg
    26581 gcgcaaagct tgatttactt tcctgctaat attgctgcat tatcgattat ctttgcgaca
    26641 caattgacga acttattaca attatctacc gattatcttt tgttgattgc agtgatcacc
    26701 gctgtttctg tgacagggtt gaatttgtta gggacaaaag tcggtgcttc tgtacaatca
    26761 gtgacgttga ttgttaaatt aataccaatt gctgtgattg tcatatgggg attattgacc
    26821 ccaggacaag gaactgtcca gttatttcca atcgaagctg gaaaagatgt tacttttgtc
    26881 gaaggattga gcagtgcgtt gttagcaacg ttgtttgctt atgacggctg gttaggtgtc
    26941 ggtgcaatgg caggggaaat gaaacggccg gaaaaagatt tgcctaaagc aattattctt
    27001 ggtttgagtt ttgtaacagt cgtttatcta ttgatcaatt ttgttttttt gaaaactttg
    27061 ccgattgatc atcttgccgg taatttgaat gcagcttctg aagcatcaga cgtcattttt
    27121 ggaggaatcg gtggaaagct ggtcactatt gggatcttga tctcggtata cggtgcattg
    27181 aacggttata cactaactgg gatccgcgtg ccttatgcga tggctttaga agacgagcta
    27241 cctttcagta aacagctgac aaagctttca aagaagttta cggttcctta tgttcctgcg
    27301 gttttccagt tagcagtagc ttgtattatg atgagccttg gttctttcga ctttttaaca
    27361 gacatgttga tttttgtgat gtggctattc agtttactga tttttatcgg tgtctttatt
    27421 ttaagaaaaa aagcgccgga attgccacgt ccatataaag taccacttta tccaatcgtt
    27481 ccgattattg cgattctcgg tgctattttc attttaggta tgacgatgat gacgcaaacg
    27541 aaattagcat tgatcggtat aggtgttacc ttgataggta tcccagtcta ttatcaaaaa
    27601 aagaaaaaac gctcagaaga gtaaaatatt tcaacaacag acagaaaaag tacgaactag
    27661 gtcctctaga tcttcgtgct ttttctattt caataaaaca agttcttcta ttttgatttt
    27721 tgctacttct gcaagtagtg cttatgtgct aaagtaagaa tgaaaaggag agataaacat
    27781 gatatttgat tctcataccc atttaaatgc tgaacagttc aatgaagata ttccagaaac
    27841 gattcagcga gcacaagaaa tgggggtaac gaaaatggcg gtcgtgggct tcgatacgcc
    27901 aacgattgaa aagtctttgc aattaagcca tgactatcca aatatataca gtattatcgg
    27961 ctggcatccg acagaggctg gcagttatac gaaagaaatc gaaaataaat tacaagaaca
    28021 attgacttta ccaaaggttg tagcattagg ggaaattggc ttggattatc attggatgga
    28081 agacccgaaa gaagtccaag ataaagtatt tcgcagacag attgctatcg caaaagaaat
    28141 gaacctacca atcagtattc atactagaga agcacttgaa gacacgtatc aaatcctaaa
    28201 agaagaagat gttcgagata tcggtggaat catgcatagt ttcagtggtg attatgaatg
    28261 ggcaaaacga tttcttgact tagggatgca tatttcattt agcggtgtcg tcactttcaa
    28321 aaaagcatta gacgtccaag aggctgcagc aaatgtacca atcgaacgat tacttgtgga
    28381 aacagatgcc ccttatctgg caccagttcc ttttagagga aagcgaaatg aaccaggcta
    28441 tactcgttat acagtagaaa agattgctga acttcggaat cttccgacag aagaagtggc
    28501 tgcccaaaca tggacaaatg cgcaccgatt atttggtcta agcgaacatg gataagatga
    28561 agatccaaga gattatagtc gttgaaggaa aagacgatac aagaaggctg cgggaagtag
    28621 ttgatgcaga tacgatagaa acaatagggt ctgcaatcaa tgaagagatc ctgatgcaaa
    28681 ttgaacatgc ccaagagact cgtggagtga tcgtttttac cgatcctgat ttttcaggag
    28741 aaaaaataag aaaaatcatt atggaagctg ttcctcaggc aaaacatgct tttttgccgc
    28801 gcacacaagc taaaccaaag aaaaagggaa gccttggtgt cgagcatgca agtgatgctg
    28861 ctattttaga agcattgaaa aaggtcgtga cgccagacat ttcccaaacg gctgtttctg
    28921 aaatcactag acaagacctt ttagactatg gtttaatagc tggggcacaa gcaaaagaaa
    28981 aacgagaaaa actaggtgac gagttgcgca tcggttacac gaacggcaaa caattggaaa
    29041 aacgtttgaa gatgtttcgt attacgccga aagaactcgc ccaagcaatg aaaatagtgg
    29101 aggaacaaca tgagtgaata tcgtgaaatt gcgacaccct ctagaacaaa agagatttta
    29161 ttgaaacatg gtttttcatt taaaaaaagt ttaggacaaa attttctgac tgaaccaaat
    29221 attttaagga aaatcgtaga aactgcgcaa atagatgaac atacgaacgt gatcgaagtt
    29281 ggaccaggaa tcggtgcatt gacggaacaa ttagccaagc atgcaaaaca agtcgtagca
    29341 tttgagatcg atgatcgttt gatccctgta ttggctgata cgatgcaacc ctatgacaat
    29401 gtgactattg tacatcaaga tattttaaag accgatttgt caacagctgt tagagaaaca
    29461 tttcatgagg agcttccgtt aaaagtcgta gcgaatttac cttactatat tacgacaccg
    29521 atcatgatgc attttcttga atcagatttg gttgtggatg aactagtcgt catgatgcaa
    29581 aaagaagtag ctgatcgtat ctctgctgaa ccaggaacga aagcttatgg ttcattatcg
    29641 attgctgttc aatattatat ggaagccagt ttagcattca tcgtaccaaa aacagtattt
    29701 gtccctcagc caaatgtaga ttcagcgatt ttgaaactga caagaagaga tataccggca
    29761 gtcgaagtga cagacgaaaa agcatttttc cgattgacaa aagcggcatt tcagcaaaga
    29821 agaaaaacgc tttggaataa cttgcagcat tcgtatggca aagatgacca gacaaaagca
    29881 tggttagcaa aaagcttgga aacagctgga atcgatccaa aacgtcgtgg ggagactttg
    29941 tcattacaag aattcgccgc attaagcaat gcgatgtcag aaaatatgca gtaaaaaaag
    30001 aggttgtgac agaagttgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca
    30061 aaaatagttc ctcatgtttt tcgtttgttt gggcttgtta ccgcagatgc aagcttttga
    30121 acaccgttta agaaagaggt tgtgggcctg ccgtttaact ctaagtcaca aggaacaatt
    30181 tcaaaaaaca gcttctcatg tttttgagtt agttggtctt attacttgat gcaagctttt
    30241 gaccactatt atgccgaaca aggagatgtg acacaaattt tgtcacatct cctatttttg
    30301 tttcttgatc aaaaaattct tatacttgat actcacactc attttgtatg gatttagaaa
    30361 agaatatgtg tcttgacagt tattagtaag tgagttatac taagtcgaca tttatgtgtc
    30421 aagacatatt aggagagaga aaaaatgaga aaaaattcag ttcgaaaact aacgatttct
    30481 gctttattga ttgggatggg ggtcattatc ccaatggtca tgcctaaaat catgattcca
    30541 ccagcttcct ttactttggc gtctcatgtg ccattattta ttgcgatgtt ttttacacca
    30601 ggagttgcag tggctgttgc gctaggtacg acatttggtt tctttttaac aacgccggtt
    30661 atcatcgcat tgcgagcatt gtcacatctt gtgtttgcgt tgattggggc ttggtacttg
    30721 caaaagcatc cgagtatcgt tttaaaaaat ggacagttta cttttgctaa ttggcgtttc
    30781 caagggttca attttgtgat cggtgtgatt cattctttag cagaaatgct agtagtcagc
    30841 atcttttact ttattggtaa tatgcctgaa acatattatt ctcaaggata tttttataca
    30901 gtattcatct tgatggggat tggtgggctt atccacagtt tagttgatta taatattgct
    30961 tattttatag caggaacact cagcaaatat tttgatatcc ccgtatttac ggcagcaaaa
    31021 aaagaaaatc ggaaagagtc gattcaaggg tacgcgaaga aaacgacata ttagacatga
    31081 tctctcaaaa aaaaaactct catctagtaa tggataataa atcctctaag atgagagttt
    31141 tttgtcctaa aaagagctgc accaacatct tctggcacag ctctaacagg gggcaattta
    31201 tggaagtttg atgacttgtt ctgtttcttt atcaaagaag tggcctttgc tgatgttgaa
    31261 ggcaaggtcg actatttcgc ctggtttatg gaaatctctt gcatctactt ttgagatgaa
    31321 ctcagtagaa ccagtttttg tgtaaagcat cgtttcagct ccaagtaatt cggaaacgac
    31381 aacttctgat ttcactacgg cttcaggtga agcttcaagg gctacttgtt cactgtggat
    31441 gtcttctgga cgaataccga agataacttc ttttccttca taaccttttt caactaatac
    31501 tttgtttttt ccttcaggaa tacgaagctt aagcccatgt ccatctgtga taacaccatt
    31561 tttcaatgtc acattaaaga agttcatggc aggagatcca ataaagccgg caacgaacat
    31621 attgacgggt gtatcataaa cttctttcgg tgtaccgatt tgttggataa atccgtcttt
    31681 catgataacg attcggtcag ccatagtcat tgcttctgtc tgatcgtgag taacatagat
    31741 ggtcgttgtt tcaagacgct ggtgaagttt ggcaatctca gcacgcatgg ctacacgtaa
    31801 tttagcatct aaatttgata atggctcatc cattaagaag acttttgcat cccgaacgat
    31861 tgcccgtccc aatgccacac gttggcgttg tccaccagat aaagcagctg gttttcgttt
    31921 caagtattct gtcagaccta agatctctgc tgcattgtcc acacgttttt tgatgtctgc
    31981 tttatcatat ttacgtaatt tcaagccaaa agccatatta tcaaaaacag tcatatgagg
    32041 atacaatgcg tagttttgga aaaccatggc aatatcacgg tctttaggtg ccacgtcatt
    32101 catgactttt ccgccgatat ttagttctcc ttcagagata tcttccagtc ccgcgatcat
    32161 tcgcaaagta gttgactttc cacaaccgga aggaccaaca aaaacgataa attcacggtc
    32221 tttgattgat agattaaaat cagttacaga ataattttct gcattgtcat attttttata
    32281 tacgtttttc agagccattt ctaccataat acgttccaca ctttcttttt tagttttatt
    32341 aactatttaa agtataaatg aaagcgttaa ctaacttcaa tgtcatgttg aacaagaatt
    32401 ttttcttttt tttgtcaatg tgctagtttt aagctttaat aaatatccat aagaaataaa
    32461 aactgataca ctggagtaaa taagtatgtt aacaatatca aaaggagtgt ctcttatgaa
    32521 aatcgctttg atcgctcatg accgaaaaaa acctatgatg gtgaaattag caacagcgta
    32581 taaaacaata ttggaaaaac atgaactttt tgctaccggg acgactgggc agaggatcac
    32641 ggaagcaacc ggcttgccga tccatcggtt taaatccgga ccgttaggcg gggatcagca
    32701 aattggagcc atgatttcgg aggatcagtt agatttggtg atttttcttc gagacccgct
    32761 ggctgcacag ccccatgaac cagatgtaac agcacttatc cgtttatctg atgtctatga
    32821 gattccgtta gctacgaata tcggaacagc tgaggtgcta ctaagaggac tggaagccgg
    32881 cttcctagat tttcgaagaa tcgtccatga aatagacaag catccacttt cattttgatg
    32941 gataagcgta tggaaaaata acgtttaatg ttcgcctata tgtagctata aaagctaaac
    33001 aaactgataa tatgcgatat aatacgaacg tattggataa tataaacaat aatattagtt
    33061 tttcgtattt gcagtaaatg tgaaaatatg ctatagtttc tgtgggaaaa gatcccaaaa
    33121 ataatacaga gtagaaaata aagcgttaag tgctaagagg atgggatgtt gcctcttgga
    33181 cgaaggacgt aatgttcgcg gttttatttt cgcattcgct gcatgatacg atgtagcagc
    33241 tcttaaagga gatgctaaaa atgaagaaac accggttaga cgcacgtatg attgctatta
    33301 tgggcttatt gattgcattg atggtcactt tgtcccgact ggtagcaatc gagaccccat
    33361 ttattaaaat cagtgtcaca tttattccac aagtgatcat gggcattctt tttggtcctt
    33421 tttggtcagg gataggcgca gttttagctg atttagtagg aatggccctc ttctcgaaat
    33481 ctgcattctt tattggattt acattgaatg catttattga aggagcaatc tacggattct
    33541 ttttctatcg aaaagagatc acttggaaaa atgccattct ggctacgctt agtgtcacgc
    33601 tgatcatcaa cttatttttg acaccattat ggcttgcgtt gatgtaccat gtgccattgt
    33661 tcagctgggt cgtttgggcg ccccgcctgt taaaaacagt aatatggtta ccgattcaat
    33721 caattgccat ttattacgta ggacgtagta ttccttacaa aaaaatttta agaagtttag
    33781 cgatccacgc taaataaaaa acaagcagtc ttcccatccc agaagactgc ttgtttttat
    33841 tgtgctgtga attgtgcttg atagagccgt cggtaataac catctttttg aagcagctca
    33901 tcatgggtgc ccatttcgac aatagctccc tgatccatca ctaatatctg gtccgcattt
    33961 ttgattgtgg acaggcgatg ggcaatcaca aaactggttt ttccttccat cattgctaag
    34021 aaggcttgtt ggattttttt ctctgtcaat gtatcgactg agctggtagc ttcatctaag
    34081 atcaacatag ggggattact gatcatcgtt cgagcaatcg tcaacagttg gcgttgtcca
    34141 tctgatatct ttaacccttg accgccaatc ttagtatcta atttttccgg caaacgttct
    34201 acaaattcat acatataaga ggcttttagg gcatcattga tttctgcgtc acttgcttcc
    34261 ggattcccaa aacgaagatt ttctcgcaat gtactgtcaa atagccaagt atcttgtaac
    34321 accattccaa aacttttacg taatgtatca cgttggatag agcggatgtc atggtcatcg
    34381 actgtaattg ttccttttgt tgtgtcataa aaacgcatca gcaaattaac aagtgtggat
    34441 tttccggccc ctgtttttcc tactatagca atggtttgac ctggataagc agtaaaattg
    34501 aaatcttcga tcaaacgctg cttggggtca taagaaaaag aaacatgatc aaaagagact
    34561 tttcctttga tatttttggg ttccaaggca taggcatctg gcaaatcagg cttttcttct
    34621 ggctgatcga tcaaatcaaa tgctcgttct agaccagaaa aagcggtttg cagttgtgtc
    34681 gtgattccag aaagttcgat aaatggttta gaaaactgac ttgagtagat cgtaaagctg
    34741 gaaatcacac caacagtgat tgacgaacca ctcttcaatg ccaataggcc gccaactaaa
    34801 ccaatcgata aataagcaag gtgatctaca aaacgagaag acgggtttgt caaggaagaa
    34861 gaaaattgtg cccgttgtcc tttttcatat agatcagcat ttagcagttc aaattgctgt
    34921 tgactagctt cttcttgctg aaaagctttc acgattttct ggttaccgat tcgttcggtc
    34981 acaaagcccg agatatcccc aataatcctt tgctgtctat cgaaatttgt ttgtgaagca
    35041 cgagcaacga tccaactcac aaggaaaata attggtgtag aacaaagaac gaccaatgtc
    35101 agaagtggac ttagacgcat cataaaaata aacgaaagaa tgatgattgc cactccagaa
    35161 aataattgat tgaaggccgc agaaattgca atggaaatat tgtccatatc atttgtaaat
    35221 cgactgacga tatttccgtg ggagttttga tcataataac gaagtggcaa tcgattcaga
    35281 tgagcaaatg catcttttct taattttgca acggataagt aagctaaccg attgcttaac
    35341 acttggatga gccattgact gactacgttg attaaaacga taccaccgaa tagaataagt
    35401 aaatggaaca gtcgattgaa gcggacctgt ccttctccaa tcatttgatc gatactttga
    35461 ccaatttgta acgtcatcac aactgttgca atcccattga tgattcctag tatcacagct
    35521 agccaaatgt cttttgcata ggcagtaagg taaggaatga atcggcggag cgtctgcaag
    35581 gataattttt ttactttcat aactattctt cctcctgtga tgcgacgatt tcctgatatt
    35641 ctgctgattg agcaagtaat tcttcatggg taccctgagc agcaatctta ccttgatcca
    35701 tcactaagat atgatgtgct tcttgaatag agcggacacg ttgggagata ataatcactg
    35761 tactgccaag ataagtctgt agcgccttac gcaaatccaa gtctgtttga taatccaacg
    35821 cacttaaaga gtcatctaaa atcagtaatg ctggcttggc aatcaaagct cttgcaatcg
    35881 tcagtcgctg tttttgtccg ccagagaaat ttttcccatt ttccatgact tttgtatcta
    35941 aaccatttgg aagctgacgg acaaattctt ctgcctgagc gattttcaga gcttcccaac
    36001 attctttttc tgtggcgtct ttcttacccc attgaaggtt ttcacgaata gtcccggtaa
    36061 atagtacaga agtttgggga acaagagcaa tttgctgacg gagatgatcc agctgccaag
    36121 aacgaacatc cattccgtcc attataactg taccggaact gacatcatag aaacgcggaa
    36181 tcaattgtgt caaagtcgtt ttcccgcttc cggttggacc aatgattcca aggactgtat
    36241 ttcgcttcag ctgaaatgta atattttgga gagaaagacc agaatcagga gtataacgga
    36301 agtcaacatg gtcaaaagcg ataattgctt cagaagaaaa atcgggagta gtactgacct
    36361 cagcttcaag aatcgaattt tctgtgtcta gcacctcttt cacccgattt cctgaagctt
    36421 cggcacgtgt gaagatcacg acgaggtttg aaacaacgat cagtgccaaa agcatttgat
    36481 tcatataatt gatcaaagca agaacttgtc cttgttgcaa gctaccaata tttactttga
    36541 tcccgccaac tgtcagcaaa cagatgatcc cgacattcat gatcaaggtt gtagcaggtg
    36601 ataatagggc agagatattg gaaacacgta aataattgtt cgctagatca tttgtgcttt
    36661 tatcgaactt ctctgtttct ttttttgtct gcgcaaatgc gcggatgaca cgaacaccgc
    36721 taagattctg actaacgtgt tcattgagct gatctagttt ttcttgcact ttttggtaga
    36781 gaggaacggt ttttttgatg ataaaaaata aaatgattga gaaaataggc aataatgcta
    36841 agaaaaacag acctacttcc cagtcgatca caaaagccat gaccactgac ccgatactta
    36901 aaaacggtgc tctgatcaat aaacgaatga ccattgctaa agctagctga agctgattga
    36961 tgtcgtttgt cattcgggtg atcaaggtat ctgttccaaa atgattcaac tcgttgtgag
    37021 agaaagtatt gatttttttg attagctgat tacgtaactc tgtaccaaat ccttgtgaag
    37081 ctactgaagc atagtattgg caaatgatag cacaaatcag accaatcaca gacatagcga
    37141 ccatccataa gcccatttca atgatttttc ctcggtcatt catttttagt ccattatcga
    37201 tcaaggaagc catcattaaa ggcaggacaa gttcgaagac agcttcaaga aatttgaaga
    37261 acgggcccaa aatgatttgc ttacgatagt cttttgcata acgtaataac tgaatcatat
    37321 gattcctcct attatttatt tgtccacaat tgaaaaaaca agtactacca cattgtagct
    37381 taggaaattt agaatgaaaa gagaacaagc cttttcataa atgaaagttt tattatgaag
    37441 aagctttaga aattgaatag actatttttt ttaaaaaaaa
//
LOCUS       DACGDM010000019        36985 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.019, whole genome shotgun sequence.
ACCESSION   DACGDM010000019 DACGDM010000000
VERSION     DACGDM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.019"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..579
                     /locus_tag="IXR05_001045"
     CDS             <1..579
                     /locus_tag="IXR05_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4259583.1"
                     /translation="DGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKEN
                     RLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQ
                     LVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLP
                     KTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1003..1173)
                     /locus_tag="IXR05_001046"
     CDS             complement(1003..1173)
                     /locus_tag="IXR05_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4259584.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1367..1546)
                     /locus_tag="IXR05_001047"
     CDS             complement(1367..1546)
                     /locus_tag="IXR05_001047"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259585.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            1933..3045
                     /locus_tag="IXR05_001048"
     CDS             1933..3045
                     /locus_tag="IXR05_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4259586.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3123..3416)
                     /locus_tag="IXR05_001049"
     CDS             complement(3123..3416)
                     /locus_tag="IXR05_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAQ4259587.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3584..3898
                     /locus_tag="IXR05_001050"
     CDS             3584..3898
                     /locus_tag="IXR05_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAQ4259588.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3919..5898
                     /locus_tag="IXR05_001051"
     CDS             3919..5898
                     /locus_tag="IXR05_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4259589.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5911..6237
                     /locus_tag="IXR05_001052"
     CDS             5911..6237
                     /locus_tag="IXR05_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAQ4259590.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6253..6771
                     /locus_tag="IXR05_001053"
     CDS             6253..6771
                     /locus_tag="IXR05_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259591.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6771..8123
                     /gene="celB"
                     /locus_tag="IXR05_001054"
     CDS             6771..8123
                     /gene="celB"
                     /locus_tag="IXR05_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4259592.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8207..9712)
                     /locus_tag="IXR05_001055"
     CDS             complement(8207..9712)
                     /locus_tag="IXR05_001055"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAQ4259593.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9804..10394)
                     /locus_tag="IXR05_001056"
     CDS             complement(9804..10394)
                     /locus_tag="IXR05_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4259594.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10573..12219
                     /locus_tag="IXR05_001057"
     CDS             10573..12219
                     /locus_tag="IXR05_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4259595.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12268..12987
                     /locus_tag="IXR05_001058"
     CDS             12268..12987
                     /locus_tag="IXR05_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4259596.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13466..14413
                     /locus_tag="IXR05_001059"
     CDS             13466..14413
                     /locus_tag="IXR05_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4259597.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14425..15345
                     /locus_tag="IXR05_001060"
     CDS             14425..15345
                     /locus_tag="IXR05_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4259598.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15386..16843
                     /locus_tag="IXR05_001061"
     CDS             15386..16843
                     /locus_tag="IXR05_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259599.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17188..17802
                     /locus_tag="IXR05_001062"
     CDS             17188..17802
                     /locus_tag="IXR05_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4259600.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17795..19519
                     /locus_tag="IXR05_001063"
     CDS             17795..19519
                     /locus_tag="IXR05_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4259601.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELRELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19516..20967
                     /locus_tag="IXR05_001064"
     CDS             19516..20967
                     /locus_tag="IXR05_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4259602.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21440..23593)
                     /locus_tag="IXR05_001065"
     CDS             complement(21440..23593)
                     /locus_tag="IXR05_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4259603.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23595..24641)
                     /locus_tag="IXR05_001066"
     CDS             complement(23595..24641)
                     /locus_tag="IXR05_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4259604.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24791..26080
                     /locus_tag="IXR05_001067"
     CDS             24791..26080
                     /locus_tag="IXR05_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAQ4259605.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26093..28795
                     /locus_tag="IXR05_001068"
     CDS             26093..28795
                     /locus_tag="IXR05_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4259606.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28780..29637
                     /locus_tag="IXR05_001069"
     CDS             28780..29637
                     /locus_tag="IXR05_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4259607.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29708..30565)
                     /locus_tag="IXR05_001070"
     CDS             complement(29708..30565)
                     /locus_tag="IXR05_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4259608.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30776..32947
                     /locus_tag="IXR05_001071"
     CDS             30776..32947
                     /locus_tag="IXR05_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4259609.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33015..33356
                     /locus_tag="IXR05_001072"
     CDS             33015..33356
                     /locus_tag="IXR05_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4259610.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33632..35386)
                     /locus_tag="IXR05_001073"
     CDS             complement(33632..35386)
                     /locus_tag="IXR05_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259611.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35397..36233)
                     /locus_tag="IXR05_001074"
     CDS             complement(35397..36233)
                     /locus_tag="IXR05_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4259612.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36235..36918)
                     /locus_tag="IXR05_001075"
     CDS             complement(36235..36918)
                     /locus_tag="IXR05_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAQ4259613.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11933 a         6500 c         7564 g        10988 t
ORIGIN      
        1 gacggcttag caccaggagt gtatcagctg gtagaaaccc aagcgccaac ggggtatgaa
       61 ttggatgcga caccaatcga gtttgagatc gaaagaagtc agacagcggt ggtagaattg
      121 acgaaagaaa atcgacttac accaggcggt gtcgtgttga caaagatcga tgaccaaagc
      181 ggagaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac cgttctgcag
      241 tcaggtctaa ccacaggagc agatggaaaa ctggcgatag atggcttagc accaggagca
      301 tatcagctgg tagaaactca agcgccaacg gggtatgaat tggatgcgac accagtaact
      361 ttcaagatcg aaaaagaaca agaagtggcg atctttttaa caaaagagaa tagaaaagtt
      421 gctgatagct cagatataag aggaaacaat ccaacaagca gtggaaataa gcatcttcca
      481 aaaactggag aaaccatcat tagccagttt atattgtcaa tattgggtgt gctacttgtt
      541 ttcatcagta taaaatttag aaagaaacga aatatatgag ctaaaataaa aaattgaata
      601 agcatagttt ttaaaatcaa ctagtaccca tcaattgaat ggaaactacc gattttagaa
      661 ggggtataca aacaaatatt agtatcggag tagagaaggt tgaacccaac cagtaaataa
      721 gtaaagacaa ttttgtgctg cgttgagaag tgaaaaataa acctttgtag taatactagt
      781 taataaaaaa tatacaaaaa cactgcgaaa atcattcttg agtttcgcag tgttttttgc
      841 ctaatgactc aagtttattg ggtaatactt tgattttctt tctacaaata atcagcgatc
      901 agttgtaatt ttttctctag ttttaatggc tctttgtcaa taaggagaaa aacaagtcgg
      961 gtcttttgtc tcggaaagct tcaaccaact cgtgaataaa ggttacgcct ccttgaaagg
     1021 cgtggaaaaa ccaagtaatc gatcaatcac caatttcgca tttggtagaa catgtttggt
     1081 gagctgaaag taggtggcgt tcatgtctgt aactaagaat tctatttctt taggattagt
     1141 gcagctaagg aaatagtttg ttaatcgagg aattttttgt gtaggtaaat tttctcgatt
     1201 aatttttctg tctcgccatc cgcggaaata aaactcagtt tatcctcaac ggaaacgtga
     1261 gaacgaaatt cacaaccctc aacactcaag acagaattct tttggaagac tttggtaaat
     1321 agcttctcaa ctctttcaat gtgcgaataa cggttgtcaa agatacctaa caacttttcg
     1381 aaataaaaaa taacgacact ttttcagtca gtaaagaagt gattttatgt ctgacatgat
     1441 ttgaaatcga gtgccttgga cggataaaat aactttgagc gttccaatgg cttcgacagt
     1501 ttttacaggt atagcgctgc ttttttaggc gtataaccat tggcatatga ttatattatt
     1561 caaagtggac aatggtttcc ttcttcttgt ttttcaccac cattaatttc ctatttccat
     1621 ctaccacagc agaaccacaa tttctacaga cacatggagc agggaagaga actgcagcaa
     1681 cgatcaatgt ttttttcttc tgtaaggttt cgtaagagac ctctgtaatc atcaaatttt
     1741 tgtctattga tctcagaatt tttttgatag aaccattcat aaagcatatc gttctctcag
     1801 ttgtttattt tgtggtgatt taatcataca agaaaacgat atgttttttt ataaaaacat
     1861 gaataggaaa aatagttgac aagaaaatga caacgccata tgatgttcca tagtatttac
     1921 aacctgtcat agatgactgt aaaaaataaa agtaaaaaga aaggacgaca acaggtggat
     1981 ttttatcagt ctctacaact agatccgttt attttaaaac aaaaaatacg agaagcagct
     2041 tctaaaaaag aaaagtgcat gtatatttgt tcattgtttt tacgatcatt attcatcgta
     2101 ttgtttgcca tttgttttat cattataatt acaacattat ttgaatcgaa gcataaacca
     2161 tacgctgtgg ttttattctg tatgttgatg agtattcgtt ttgttgactt tggttataag
     2221 atttcccatt cgatcatagg tttagcaatc gtcatgttct cactattagt agcaccgtat
     2281 gtccagctga tcaaatggtc agttatgggc atgttgattc attttatttt actaagcagc
     2341 atattaatgg caaccgctag tgatcccaaa atggggaatg cttctttgta cggcttttca
     2401 tatctcttta ttgtttattc gttacctaaa gattcgttga acaagaattt ctttacacaa
     2461 acaagtagct tattattttt gtttttttgt tggttttcag ttctccttta cagaaaacat
     2521 cgagaaaaga acaaagacaa aagcttgttt aaagagattt ttttgaaagg catgtattcg
     2581 caggaaaaaa tttggatgct catctatgca tttggcatta gtcttttgat cgttgcagga
     2641 gagtatgtcc cttttcagcg attgatgtgg gcagggtttg cattttcttc tattgtatct
     2701 agctatggat tgatgtcgat tggtttcaaa gaacgagcag tagaccgaat cattggctca
     2761 ttgattggat gtgttttatt tattggtatc agccaattta ttccttttaa ctgggtcggt
     2821 atattaggtg gtctagcttt aggtgtttgt tctacctata gatataaaac agtttttaat
     2881 tcttttggtg ctttggcaat cactgccagt ttattcgggg ttccaggagc agtaacgatc
     2941 cgcatttttg agaatatcct tggggtatgt ttaggaatca tgtatattgg ggtgactgaa
     3001 atacttatcc gaaaaataag agaaaaacac ggtttgaatc attagatgag atcgaataaa
     3061 aaataaggaa aaagtgaaga tacacatgga tgataaattg ctatcattcc atgtgtatct
     3121 ttttacggta aatcagtgaa acgttcgact ttcattttta atttatactt tttacggagt
     3181 tcgtttattt gagccatcat ttcggatttg tgatgctttt cgattgcttc ttcatctttc
     3241 caacggtcga tcagtaaaag agattctgga tcttctagtg gaaagtaata gtcatatttc
     3301 tcgtttcctt cttctgcacg aatcgctttg acaatgtttc tttcgaccat ttcttctgca
     3361 aattttctgg cttgtccatt tgtacttgta tacaaaatat tcactgtgat actcactaaa
     3421 tcccctcctg aaaaaattct atcactagta tatcacggtg ccagaaatta ttattcaaga
     3481 tatgatacac attttttccg caatgctacg gaaatatata ttttgaatag aaaacgctta
     3541 caagatatgc ttggtttata aaaataaaag gagtgattga tttatgaaaa aagcattgat
     3601 tatttgtgcg gcaggaatgt catcctcgat gatggcctca aagacaacgg atttctttaa
     3661 gcaaaaaaga gaagaggtac tcgtagatgc agtttcagct acagaaggcg ataatatgat
     3721 taagaatagt gattttgatt tatttctgat cagcccgcaa acgacgatgt ttttggataa
     3781 attcaaaaaa ttaggagaat ctgttggaaa gcctgttgtt agtatccctt tccaagcgta
     3841 tgtcccaatc cctacaggca tccagaagtt agcagaggtg atcgaagaga acatatgatg
     3901 gaataggagt ggatgataat gaaacagaag gaaaaattgc tgttgagata tttgattgat
     3961 cacaagaagg agtatgtcac cagtcaacgt ttagcttctg aattgttatt atctgatcgg
     4021 acaatccgta attacttgca gcggatcaaa gagttagtag aaaaaaacgg aggtaagatc
     4081 attgctaaac caggttatgg ctaccaactg catattttac aaagactgac atttgacttg
     4141 tttttgagtc ggcaagaaat agtacctgga tatgctagag aaccgcaagg attttatgag
     4201 tccgaagatc gacaaaagta tatattgaac caattgcttt tggaagatgc cattcttttt
     4261 atggatgatt tggcagaaga gctttatatc agtcgttcca gtttgacaaa ggacatgcaa
     4321 gaaatcaagg agcgattgat tccatattca ctaaaaatcg tttctaagca tggtcaaggg
     4381 acatggatcg aaggggaaga aagaaatcga cggcatttta tcatggatac tttttttgga
     4441 aaccattatg gaaattcatt gaaagaatat ttagggcaaa gccgtttttt cccagacatc
     4501 agttttgaag agctagtcat tatcattctc gatgaaacaa gagaagctaa gttaaaagtt
     4561 tcggatttta tcatacagaa tctgacttta cacttggctt tggggatcaa acggctccga
     4621 gaagggtttg aaatcaagga attaggcatc gaacaagaag tttctaagcg agtagagtat
     4681 caagtggcgc agcggatcgt tcaacgtatt gaggtaatcg caggtgtatc gtttcccgaa
     4741 gaagaaattg cttatttgac attacatctc atggctaagt cgaatcacaa agaaaatcaa
     4801 aatgatcagg aactatcaaa ggaattagcg aaagttctga aaagattgtc tcaggaattt
     4861 catttttcat tagtagagga tctccagctt ttcaatggac tactcgatca tttgtcaccg
     4921 atgatgattc gattgagccg aggtattcgc attgagaacc cattgactga ggagataaag
     4981 aaagaaaatc ccaaagtctt tgacgcagta aaaaggcatt tcagcaacat gccggctttg
     5041 aaaaactata ccatcaatga agatgaatgg gcctatttgg ctttgcatct catggcggca
     5101 ttggaaaaag aaagagctgc gcataaacta catgcattga ttatctgtgc aacgggttac
     5161 ggcagtgccc aactattaaa gaatcgcgta gtcagtgaat tcggtaaaaa tattacagtg
     5221 gtaagtgtaa aaggctatta tgagatcaat gaaacaactt taaaaggaat cgacctgatt
     5281 atttcttcta ttgatctttc gacaatgttt ttcaaaattc cagttttaca tgtcagtatt
     5341 tttttgaatg aagatgatgt tcgtaaaata cgaaaggtag ttggagaatc tataccctat
     5401 cattcctcag atagaccgat accagcattt tctctacagc aaaaaaagca gatttacacc
     5461 gaacagttgt ctgaaaaatt tttcaagact tatacgtacg aaccgaaaaa ggaagaaatt
     5521 cttcatgatt tgctgcaaaa gctgagcata aatgaagaag aaggatatat aagagaaatg
     5581 cgaaagcaga tccagcaacg tgaaaatatg ggacaaatca tattcagtga tacagtggca
     5641 gtcccacatc ccgctgttcc agttggaatc gaaacaaagg tagccgttgc attgattcct
     5701 tctgggatgc agtgggatca atatcaagaa attcattttg tttttttagt ttcgccttct
     5761 tatgtcgaaa atgaaggaat tacggtcgtg actaaagcaa tcgttaggtt agttgaccag
     5821 ctaaaagtac agcaggaaat cttagctgaa cctatttttg agaatttcag cagtaaattt
     5881 atcaaactga tcgaataagg aggaaaacag atggctgaaa aaataaacag tgaaacacta
     5941 caagtgactt cttttgatat cattttccat agcggaaatg cacggacact gatacatgaa
     6001 gcatttcgct cgatgcgtaa agagatgttt gaagaagtag aagagaagtt gcgacaagca
     6061 aatgaagaga ttcttcatgc gcatcagtca caaactcaac ttctgaaaga atatgccagc
     6121 gggacaaaaa tagaaatgga aattatcatg gtccatgcac aagatcatct gatgacgacg
     6181 atgacattat tggaagttgc acaggaaatg aattatttgt atcaaaaaaa taaatagaaa
     6241 ggaaggatca ttgtgcagga tacagtaaaa aggaaaatcg aattagaaaa aaagcaactt
     6301 agtttgaaaa acatgtattt caatcgttat ctaatcgtac gttacctgac tgcctttttc
     6361 tttttcatga acatgcaatg gatgattctg cttctatcag ctaaaagttt aggaagtagt
     6421 ttaccgatga ttctgatttt agctattttg cctgcagtag gagaacaagt aaagctttat
     6481 cgaaaacacc aaacgaacgt tccatggaca aagtggtatt ttttgttcca gagtgtcttt
     6541 aatttattag tgattccagt gttgtttacc tcaggattta cattcttgta tccttttatg
     6601 gcaaataaca atggaggaca gttatttgtt ttcattcttg ttgtaagcgg tatttttgcc
     6661 agtgcattta tacagtatcg tttaaagaaa atttcactca accaagacca acagtatatc
     6721 cgtattaaac aatatgaaaa agcgttatat ttaggaaagg agaataacta atgtttgatt
     6781 ttttgcagaa atacctgatg ggacctatgg ggaaaattgc gcaacttaaa atcgttcggg
     6841 ctgtcatggc agcggggatg gcttctattc ctttcacgat tgtaggctcg atgtttttgg
     6901 ttttaaatat tttgccatta ccgttcccat ttttagaagg attttttaat gcaacttttt
     6961 tcaaagttag tgacttgtac atgatcgtca atacaatgac gatggggatt ttatctattt
     7021 actttgccat tgtgtttgct tatgaattaa cgtcaattga acgagatgaa caaaaattaa
     7081 atgttaatcc gctcacgggg gcattactat ctgtttttgc attctttatg tgtatccctg
     7141 aattgatcat gactgatggt aaaatcagct tgattgcttc tatcaatgag acagaaactg
     7201 tagtaaatgg tattaggatg ggctcttttg tcgaacgttt aggaacttca ggaatcttta
     7261 cagctattat tatgtcgatt attgcggtcg aattgtattg tatgtgtgtc aagagaaatt
     7321 gggtcataaa aatgccagat gttgttccgc caggagtttc tcgttctttc actgctctga
     7381 tcccaacatt tgtcattgcg tttgtggtga tgatcatcaa tggattatta gttgcactag
     7441 gaacggatat cttcaaaatg attgctatcc catttgggtt tgttacgcag ttgacgaata
     7501 catggcttgg tgtcatggtg atttatttct tgatccatgc attgtggatc gtagggatcc
     7561 atggagcgaa tatcatcact tctttcttga ccccgatcgt attagctaat atggcagcta
     7621 acgcacaagg cgcaaattat ccgttggcag gagaattcaa caattcttat gtaaccgttg
     7681 gtggatcagg tgcgacttta ggattgatca tctttattgc attcctcgcg aaatctgatc
     7741 agctgaaagt gttaggaaaa gcctcacttg taccaggatt attcaatatc aatgaaccaa
     7801 tcattttcgg gatgccaatc gtctacaatc cctatttagc ggttccgttt ttcttagctc
     7861 cgatggcttc tgctacactc gcttattttg ccattcggct ggaaatcgtc aaaccgatgc
     7921 ttgcacagat gccgtggcct tcaccagtcg ggatcggagc atttgttggt agtggtggtg
     7981 attggaaagc tgctgtgtta gcagtcattt gtgcaatcat cgcattcatt atctggttcc
     8041 catttatcaa attctatgat aataaattat taaatgaaga aagagaaaag gcagcagaat
     8101 tagctagtga aaagttaaaa tgatttctaa gaaaaaagga actgtgacaa aaaatcacag
     8161 tccctttttt tcttagaaat gggaaaccac tagtatataa ataccattat tcttcaatca
     8221 accgcttcac gattgcataa tccccttcat aaggttcatc tacaccattg attttttgat
     8281 agggatccac gccttttccc gcaataacga ctgaatcttg cggagcgctt tctgctaaag
     8341 cgcgtcgaat cgcttcagga cgatccattt cataatgaac gatcaaatct ggattagtaa
     8401 ttgcttcatt gatttcttcc gcgatttttt tcggatcttc aaatgctggg tcatctgccg
     8461 tcaaaaaggc gatgtcagct gtttctgata gcacttttcc aaaatcatgt cgacgggaga
     8521 ttgctttgtt tcctgggctg cctaatacaa caattacacg gccatctgga tgttcatttt
     8581 tggcaaattt cagcaatgtt ttcaagctta gataattatg tgcatagtcc acatagacat
     8641 gcgctccatt ggattggatc aattgatcca ttcggcctgg tacacgagct tcttttaatc
     8701 cgtcttgtgc atcttgactg gaggcacctg ttagtgctgc ggcaatgatc gcactggctg
     8761 cattttcttg gttgaatcct ccagccagca aaatatcata agcagtatcg cagatagcta
     8821 agcgatcttc atgagaagat aaagtaaaac cgtgagtacc tttatctgaa cggatcactt
     8881 gataattgct ttcttccgaa cgaccataag tgatcgttgg aatctggaat agatcggctg
     8941 tttccctaag taaatcaaaa tagtcacttt catgatttaa aacaactgtt tttgaattca
     9001 agatcaattg tcgcttgcaa tagaaatagt catcaaatgt cggatgttcg atcggactga
     9061 tatggtcagg cgagatattc aagaagattc cgacatctaa agtcaagccg tatacgcgtt
     9121 gtgttttgta agcttgtgaa gaaacttcca tcactagatg agtcatacca ttttcaactg
     9181 cttctgacat catacgatat aaatctaatg actcaggcgt tgtcaaatgg gatttgaaat
     9241 atgttttgcc atctaacgtt gtattcatag tagaaagcaa tgctgttttt ttatttgttg
     9301 tgtgatccaa gattgctttt gtaaagtacg cagcagttgt tttacctttt gttccagtga
     9361 atccgatcac tttcaattta ttttgcggat agtcgtaaaa agccatagca agaagcgcca
     9421 ttgctttacg gatatccgtt acgatgattc ctactgctga attttcgtat ggttgttctg
     9481 atacataata ttgaataccc tgttcgattg ctgaatccaa atattcttct ttgaaattca
     9541 ttcctttaca gaaaaacaaa gtagaagcat cagcttttct tgaatcataa cttaactgaa
     9601 gaaattcagc tttttctggt acatcaagat gccagcctct tgttgaaaca aattctttta
     9661 atagattttc ttttaatagt aaatgacgga tgtcttctaa agagaagctc attgattgat
     9721 ccctcgcttt attcaatttc ttggtttatt atagcacact ctttttaata tatcgtttgt
     9781 ttccgctatg acaaaatcca gctttattca aattttcttg acacagggga caagcggatg
     9841 agtattttca taaacaatga actgactgta atagatagga gaacgaatag tgtctccaac
     9901 aatccaaaaa cataataatt caaaaagacg ataagactat tggtaagtaa aagtccttgc
     9961 ggcattggaa gccgaaaaaa tttgtggaaa ataatcggcg gtatcgttat accgccattt
    10021 gaggccccga ctgtgtacaa tgtgtaaacc ccaagactga acaaaagact tcctgaaatc
    10081 agtgaaaaga aatgtgagga gatcatttcc acttttggaa caatctctaa aacaacagga
    10141 aaaagcagac ttcccgctac agtcttaaaa aatactgatt ttcctaatag gacagcggct
    10201 agaagcagca tcataagatt gatgctccaa acagtaactg agcgttggat agaaaaggcc
    10261 gtttcaacta aatgtccgat ggcgcccact ccggcggaag ctatatcgtg agggagcaag
    10321 aaccaattca atccaactgt gataaagaaa agacctaaaa atataacggg tagttttttt
    10381 atttcttgtg tcattgatat ctcctataaa tgttagccat aaaaggctgt atatttcttt
    10441 actttaccaa aaaaacgaaa ccgaattcaa aaaaacaatt gttcttataa aagttatata
    10501 aaatcgattg ccagtttctg ttttaccaat taaaatgata gtaatgtttt gtagaaagtt
    10561 ggaatctgac cgatggataa tcaaagaaaa ccagcattag atcaattaac accgcaagaa
    10621 aaaatggcac gaggctctgc ttggatgacc gccagtaata tcatttcaag attgctaggc
    10681 gctgtctata tcattccctg gtatgcttgg atgggcgaaa atgctaaggc tgccaatgga
    10741 ttattcaata tgggatacaa tatatatgca ttgtttctac tgatctctac agcaggaata
    10801 cctgctgcga ttgcaaaaca aactgcacgc tataattcat tgaatgaata tggcacttca
    10861 cgacgattat ttatccgtgc attacagatg atgggcgggt taggcctgtt gtttgctttg
    10921 ttcatgtaca tcgcctctcc ttggctagct catgcttctg gtggcggaga agaactgatt
    10981 ccaacgatgc gttctttgag tatcgctgta ttggtttttc cttgtatgag tgtgatacga
    11041 gggtatttgc aaggcaatca agaaatgatg ccttatgcgc tgtcgcagat tgtagaacag
    11101 gtggcacgta ttttttatat gctattggct acattcatca tcatgaaagt catggatggt
    11161 gactatgtga cggcggtcac gcaatcaact ttcgcggcat ttatcggtat gctagcaagt
    11221 attcttgtcc ttttgtattt tttgaagaaa catcaagcgt atacatcggc gtttattcac
    11281 tacagcgaaa acaaaataaa tattgcaacg aaggaattgt tgttagatac cgttaaagaa
    11341 gcgattccgt ttattattgt gggttcaggg gtaacgatct tcaaattagt cgatcagttc
    11401 acttttatga agatcatgtc tgcatccacc gagtattcca atgcacagtt actggatctt
    11461 ttttcgattt ttagtgccaa tccagataag ttgacgatgg tagttattgc attggcaaca
    11521 tcgatcgcgt ctactgggtt accgttgatt acagaagctg ttacgttgaa agatcgagta
    11581 ggtctggcaa aattgacaag cggaaattta cagttgtttt cattttttat gtttccggcg
    11641 acatttggtg ttatgttact tgcctatccg ctaaatacat tattttatac accggattct
    11701 ctaggaagta atgtactgat ccaagcaagt tttgtaggac tcttcctagg actatatatg
    11761 ctagtttcca acatgctgca aggaatgttt gaaaacaagg cggcaattaa ttatttggtt
    11821 attgggtttc tagtgaaact ccttcttcaa tacccagcca ttcgtttatt tgaagtatac
    11881 ggccctttat tggcgacaat gatcggattt gctgtgtctt gtaccttgat cttaaagaga
    11941 atccatgaag tagcccgctt taaaccaagt tttgtctggc gcaggacatt gctgatcttt
    12001 attcttacct tgattatgct tttggcttcg tggatcacaa agatgatttt tggtgctttt
    12061 ttaaacgaag atagcaaatt ccagtctcta ttgttgattc ttgtagtagc aggtataggg
    12121 gctttagtgt atggttattt agctttgaaa atccgcttgg cagaaagact actaggacca
    12181 ggaatagcgc gtttacgaca taaattaaaa ataaaataag tgaatcagaa gagctagatt
    12241 gatgctcttt tgaaatgggg gaaacgcatg cgtttagata agtttttagc agatatggga
    12301 cttggcagcc gcaaagaagt caaaggatta atcaaaaaag gaacgatcga agtcaatgga
    12361 caagtggtga aaagcgataa agcgcaagta aatgaattcg aagatgcggt tacttattta
    12421 ggagaaatca ttacgtatca aaaagatttt tactacattt tgcataaacc tgcaggagtc
    12481 atttctgcta ctcaggataa tcatgatcaa accgtaatcg atttattgga agaccaggat
    12541 tatcgggaag atctttttcc agtcggccga ttagataaag acacagaggg cctcttgatt
    12601 ttaacgaatg acggggtgtt tgcccatcag ttactatcac ctaaaaaaca tgtggagaaa
    12661 gaatatctag ctgaggttag cggtataatg acagaagaag atatccgttt atttgcagaa
    12721 ggactgatta ttgatggcga tgagcagaca ttgccggcaa aactccaaat tgatcaagta
    12781 gatcaagaga cagaaacttc aattatccgt ctgattttgc atgaaggaaa gtttcaccaa
    12841 gttaagcgaa tggtcaaagc agtaggaaaa gaagtcttat atttaaaaag aatccgtatg
    12901 ggaaaatttt ggctgcctaa agatttgaat aaagggcaat atcgacccat gaccaaagaa
    12961 gagctagaac aagtgagaga aaaataattg aatggatagc taaaagaata agcagagtag
    13021 ttgtagcgcc atctgaaaag cagacttgtc cgtctgactt tcggatggct tttttgtgaa
    13081 atttcggctt atttccgtag aagctacttc tggaacaccg tttgttcgga ataagggact
    13141 gtgacaagac ttttgttaca gtccccattg ttccttgtga ctcagagtta gatagtaagg
    13201 acacgatctc cctaatactc aggccaaaac gctgaattca caacctctga taaacggtgt
    13261 tcaatcagct gaccctcggt attagctcaa aaaacggcaa aatatgagga actattttcc
    13321 cgtttttttc tctaatactc aggccaaaac gctgatttca caacctctcc tatactttgt
    13381 ttcattttcc ctatactttg tttatttatt ctcattattg aaagcgctat aattacgttg
    13441 cgaatgaatc gaaaggggtt tttagatgaa aaaacgaaag gggttcaatc atttttttat
    13501 gaatctatgg cgttataaag cacttgtcct gatggctgta ccgggtatgc tttggatgat
    13561 ttttttcttt tacatacctg taatggcgaa tgtcgtagca ttcaaaaatt ttcatatttc
    13621 agcagatggg ttcttggcta gcttgaggga aagtccttgg gtgggttggg aaaatttcaa
    13681 atttttattt tcttcggatc aagcatttct catcactaaa aatacaattt tatataatgt
    13741 agcatttatc cttttgaatc tgctgatctc agtcgtattt gcaatcatta tgagcgagtt
    13801 gagaaataaa cgactcgtta aagtttatca aacgatgtcc ttactacctt attttctatc
    13861 ttgggtcatt atcagttact ttgtttacgc ttttttaagt cctgacaaag gaatattcaa
    13921 tcagtggatc actggacatg gaggagaagc tgtcaattgg tataatgaac cgaaatattg
    13981 gccgtttatc ttggtgttca ttggtacatg gaaagggatt ggttataaca gcattattta
    14041 ctttgcatct gttatgggaa tcgatccgac ttattatgaa gctgctatgg ttgatggagc
    14101 tagcaaatgg cagcagatca aacatgtgac gataccacaa cttattccac taatgacgat
    14161 tttaacgatt ttagccgtag gaaacatttt ccgagctgat tttggcctgt tttataacat
    14221 tcctaggaat tccggtgcat tatatgatgt gactcaagtt ttggatacgt atatctacaa
    14281 tggcctgaca tccacaggag attttggtat gacggctgct gcaggacttt accaatcagt
    14341 tgtcggcttt gtcttgttga tgatcacaaa tacgatcgcc cgacgttttg atagcgattc
    14401 tgcattattc taaggaggaa aaaaatgaaa aaaaagaaag tggagagagt ccaagtccgc
    14461 tctttcaata agacggctaa ttttttctct aatataatga ttgcactctt tgctatttcc
    14521 tgtattttgc catttatatt tgttatcgcc atctctttta ccgatgagtc catattgtcg
    14581 actcacgggt acagtttttg gccagaaaag ttcagtatat ttggttatac gtacttgttc
    14641 gaccagatgc aggataaaat tttccaagcg cttttcgtca ctgtacttgt tactgtttta
    14701 ggtacactga tcaatagcac ggctacttct ttatatgctt atgcgatttc acggtcaaac
    14761 tttccattcc gtcgtttttt taccgttttt tgtttgatta cgatgttgtt ctcaccaggg
    14821 atggtggcca attatcttgt tatgacaaat cttcttcagt taaaagatac gatttgggca
    14881 ttgatcttgc caatggctgt cagtcccttc aatattattg tgatgcgcac attctttaaa
    14941 cgttcggtct ctgattcgat tattgaatcg gcacggatcg atggagctag cgaactgcga
    15001 atatttgttc agatcgtttt accgttagct gttccaggta ttgcgacaat cagtttattt
    15061 gccgcattgg gttactggaa tgactggttc aatgctttac tatacatcca agatgataag
    15121 ctagttccac tacagtatct tttgatgaaa atccaaagta atattcaata tctgacacaa
    15181 aattcaggag caggaagcca attgacaggc ggattagcct cagttccagg agaatctgcc
    15241 agaatggcga tcgtagtcat ctcgacgttg cctattgcga tcagctatcc atttttccag
    15301 aagcattttg tcaaaggtct aacaatcggc ggagtaaaag aataaagaaa caaaaatata
    15361 aatcataaaa ttaggaggaa gaaaaatgaa gttatggaag aaactagcct ttacaggtgt
    15421 ttcagcgttg ttgttgggaa cattagcagc atgcggaggt tctggttcta aagaccaggc
    15481 agaagctagc aattcggaca ctttgcagat gtatcaaatc ggagataaac cagataattt
    15541 cgatcaattg atggaagtag caaacaaacg aatcgaaaaa gagatcggtg taaaagtcaa
    15601 tatcaattac attggctggg gcgattacga aaagaaaatg aacgtcatca tttcttccgg
    15661 ggaaaattat gatatcgcct ttgcgaacaa ctatgtttcc aatgcccaaa aaggagcctt
    15721 tgctgatttg actgaattag cgcctaagta cgctgaaaaa gcttataatg atttagatga
    15781 agcatatatt aaaggaaatc tggtcaatgg aaaattatat gctttcccag tcaatggaaa
    15841 tgtctttgct caacaagtac ttacttttaa caaagcttta ctagataaat acgatctttc
    15901 aattgatgga atccaatctt acgctgatgc agaaaaagtc ttgaaggaat tccatgaaaa
    15961 agaaccaaac acggcagctt ttgccattgg acaaggcttc aaagtccaag ggaactttga
    16021 ttatccttta gggaatacgt taccatttgc tattgatctg gatggagatg attcgaaaat
    16081 catcaaccaa tacgataatg aaacgtatat cggactgtta cgtacaatgc atagctggta
    16141 caaacaagga ctcattccaa gtgacgctgc aacgagcaat aaggattatc cactagaagg
    16201 aaatacttgg ctaatgcgtg gagaaacaca aggaccgtat gattatggcg atacaatttt
    16261 gacaaatgca gcaaaacaag aacttgtctc aaaagcaatt actgttccac taaaatctac
    16321 agctcaagca caaatggcaa attttgtcgt atcaaatact tcaaaaaata aagaaaaatc
    16381 agtagaactt ctagggctgc ttaacagtga tccagaatta ttgaatgggc ttgtttgggg
    16441 gatcgaggga gaagcatggg aaaaagtcga tggttcagat gataaaatca aattgctaga
    16501 tggttatcag ccaaatacac atatgtctgc ttggaataca ggaaacaaca agattctata
    16561 tacacaagag tctattacgg atgacatgat tgccaaacgt gatcaatcga ttgctgatgc
    16621 agaaacttca ccgattttag gattcagctt caacactgac agtgtcaaaa cagaattaag
    16681 taatatttct aatgtcatga atcaatattt agatggattg aatacaggga ctgttgatcc
    16741 agatgaaaca ttaccgaaat tgaaagacgc tttggacaag gctggctatg ataaggtatt
    16801 gaaagaaatg caaaaacaat atgatgagtt ccgacaagaa taataatgaa taaagacaaa
    16861 ggggttgtga caaaagacgt gtcacaacct cttgttccga ataaacggtg ttcaaaagcc
    16921 agtttctcgg tattaagcta aatatatgta aaaatgtgga aagccatatt cacaaaattt
    16981 ttcttactac tcgaaactaa gcggctattt cacaaactct tggtaaacgg tgttcaatca
    17041 gctaaccctc ggtattcgct cacaaaacga caaaatatga ggaactattt ttccgtttgt
    17101 ttctctaata atcaggtcaa ggtgctgatt gcccaacctt tttttgtata atgagaaagt
    17161 ataaacttaa tgtttggagg agaagatatg ttagggaagg ttttggaaga gttatttatc
    17221 cggatctggg tcattataaa actaaccttg tatttctgga tatatacatt tgccggcggg
    17281 atcatctttg gattaggtgc ggcatggaaa acagtcaatg aactatttta tttgtacgga
    17341 ttcgagtata aagaaatcac aataaaaaga ggctggaata tatataaaag aaatttttta
    17401 agaggcaatc tgctatttag tttattttta tctggtactg ctttattgag ttacaattta
    17461 tatttatctg ttcaaatcaa agggctcatt tttttagcta ttgattttat tttacttttt
    17521 gccttgctct gcctatttgc tacttatcaa tacagtatga ttttagatag tgaatatacg
    17581 atctctgttc ctaatctgct aaagctaagt tttatttcgg ttttttccag cttttcgtct
    17641 tttctaaaaa taattattgg tagcggtata attttaggcg tgacttggca attcaaagga
    17701 ttgatcctgt ttggtgtcat tggtcttttg acggtttgga atggtacgat gacaacacat
    17761 tggcgtgaag aattagataa acagttggaa agttatgaat aagtttcgga ttctattttc
    17821 aaaaggaacc ttactaaatc gtctgttgcg gaaatacgcg gttatcatga tcggtgtaac
    17881 gatgactgct accgttattt ttagtatcca tacttgggaa caaaatcaaa aacaggcaga
    17941 aaacatgaca agtgatgccg ttcaaagcac aagcagaatg ctgaatgata aaacaacctt
    18001 gagtaggatc atcaaaaacc agcttgtagg gaattccgaa aagatcgaaa atgtgacgac
    18061 ctacttaaca aaacccatag atcagtatct gatgtatgta tacgaacagc aaaacagtac
    18121 cgatgaatta gtttctttcc caaatcaaat caaagatctc tacgcaaatt atgaagaact
    18181 aagtgcgata tatatcgtgt tgaatcaact accggagtat tatgaatctt ctagagaaaa
    18241 caaaggtggg gaaataaaaa aggggacacc aaaattacta gacgcctttt atatcaagtt
    18301 gcctatcaca caaggaggag ctgagtcagg aagtattttt attggttttc aaaagaaaga
    18361 actagatatg attttagaaa atctaacgtc attcaatgga ctctctttat acatgatttc
    18421 tggaacgaca aatcgactat acacattcca tgataataaa atagctaaag aaacgtttga
    18481 aagacaagaa atgatcatca cagagagtct gaagaaaaat tcacaattgc cgattgacga
    18541 tctggaaaaa aacaattttg ttcaacacca agaactgtct gatgattatc gtatattagc
    18601 tgtactagat aaaaaaagtg taaaaatcga aacgggaaaa aatcttgccc cgctgatcat
    18661 tggtatcatt attttagaca atatactgct tatctttctt tataaaacat tcaaacgata
    18721 ttcacagcaa gtatctatcg tcatgcaggc catggatcaa acagcagcag ggaatttaga
    18781 gacgcggatc gacataacaa acacggaata tgaactgagg gaactttcaa tcggtatcaa
    18841 cgaaatgttg gatagcatca atcagtttgt agaagacatc tacaaattag aaatcaaaca
    18901 gcaagacgca catatgcggg cgcttcaagc acagatcaat ccacactttt tatataatac
    18961 attagaatat atccgaatgt atgcaatcag cgaaggaagt gaagaattag cagatgttgt
    19021 gtatgcgttt tccgctttgc ttcgaaacaa tacgaatcaa gagaaaacga tcactttaaa
    19081 agaagaactg gacttttgcg aaaaatatgt ctatttgtat caaatgcgtt atcctaatcg
    19141 agtagcctat cattttatga tcgatcctga tttggaaaag atcgaagtac ctaaatttgt
    19201 gatccagcca ttagttgaaa attattttaa acacggtatt gattttactc gattcgataa
    19261 tgcgctaagt gtcaaagtct tgcaggaagg caaacgggta aggatcatca tcaaagataa
    19321 tggaaaaggg atgactgaaa aacggctaaa acagattgaa gaaaaactgt ctcatcctaa
    19381 agtggaactt cacggttcta tcggtctgca aaacgtgaat gaacgtttac gtgccagctt
    19441 cggcagcagt tattatatgt cgcttgagaa taatgagaca ggtggactga ccgtttctat
    19501 tacattcaag gagggatgag cgtgtatcaa gtgttattgg tagatgatga atacatgatt
    19561 ttgaatgggt taaaaaagat aattgattgg caaagtttag gctttcaaat agtagcaaca
    19621 gcagagaatg ccaaagaagg actagctgta cttgaacagc gacagattga tttagtagta
    19681 acggatgtga caatgccaga aataaatgga ctggaattta ttgaagcggc tcaaaaagaa
    19741 cgtcataatt ttgaatttat gattttatca ggataccaag aattcgatta tttgaaagga
    19801 ggtatgcaat taggcgccgt gaattatttg atgaaacccg tgaataagtt cgaattggtt
    19861 gaaagcctca agaaaatcaa aacacggtta gatcagcaaa atgaacaaaa aaatcaacaa
    19921 gaaatctatc aagaactgtt attcagtcaa tggttgaatg aagaattgga tgaaataagt
    19981 gaagaagaaa taataggaca aataagtgag aagcagcata ggatagtatt gattcaactg
    20041 gcaagaactc atgatactct tatcaataga tggttgcaag aacggcaaca aatcttttac
    20101 tatcaacgaa attacggaga ccgtgtattg atcacgttgt tgttggaggc agatgaagtt
    20161 gatggcttct gttgttttgt tcaagaaaac tttcctgatc aggaatggct gatcagtatc
    20221 ggggaagaga cagattcttt ggacaaaatc cctgaaacat tccaacaagc gaaagacaat
    20281 ctacagttgc atcaatttta tggagataaa gacgagcatg ttttttacgc agtacaagca
    20341 gaaacaaaag atcaaaccat cgatttttca agtttcagac gcgtgctgca aaataaacaa
    20401 ttggaagtcg ctcaaaaaat gatcactgat ttttttgaac agtttcagtt agcagccatg
    20461 atgccggaag atatacgata ttccagtttt ttactgttta tggagattca acgggaattg
    20521 attgatctgg aagatgagga atatttacaa ggaatcgaaa aaatccatca ggcaaaaacg
    20581 gtgcaagaac ttcagcagct acttctgtca ttcatcaaaa agcatcagag acagaaaaag
    20641 tacagtgaca atgtggaaaa agtaatcgta atcctgcacc agcattatca agaaccactt
    20701 acactcaaag aagtgtcaga aaacctgcat ttaaatgtca tgtatctagg acagctgttc
    20761 aaaaaagaaa cgaaaaaaag tttttcagct tatttgaacc atttacgtat ggaaaaagcg
    20821 aaacaactgc ttttgcacag taatcaaaac atcaatgaga tagcaagtga gattggctac
    20881 aacaacacca cgtatttctc taaattattc aagaaaatcg tcggcagatc ccctaaagag
    20941 taccgagaaa acagtggaga atcataaaag aaaaagccaa tgtaatgaaa taacttataa
    21001 aaaattgtct agaaatctaa ttttgggctg ttcttattac ttgaggcaag gcagcttttt
    21061 catgacctct cgataaacgg agttcaaaag ccagtttctc ggtattaagc caaatttatg
    21121 caaaaatgtg gaaagccatt ttcacaaaat ttttcttaat actcgaaact aaacagcttt
    21181 ttcacgacct ctccactaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa
    21241 tggcaaaata tgaggaacta ttttgccatt tgtctctcta atactcaggt cagaacgctg
    21301 atttcacaac ctctcaataa acggtgttca aaagcttgca tctgcggtaa taagaccaac
    21361 caaacgaaaa atatgaggat ctatttttgc ttggctgttc ttattacttg atgcaggaca
    21421 gctttttcac aacctcttgt taattatagt ttgataagga aaaaggcaaa tcttttgctt
    21481 gatatttctt agggtgaggg atgatcccta attggtaaga gatcgtgccg cctttcagca
    21541 aatcttgatg ggtaaaatat aatttcgtat attctctgtc catccgtttg attttatgga
    21601 taaattgttg ctgcggccga ttaggcgttg cttcaatcgt caattccttt ccatttgaca
    21661 aaagcaaaac agccttgtca attaatggca taccgataac atattcaccg gttccaggcg
    21721 tgacaggata aaatcccaga ctattgaaga tataccaagc ggccatactt ccattgtcct
    21781 catctccagg gtaacccatt ggagaatcgt cgaaggtctg agtcatcaac tgtttaagca
    21841 gtggctgtgc catttcaggt tgtcctatat aactgaacaa gtaaggatag tgaaaacttg
    21901 gctggtttga aatagctaat tgtccaaatt ctatcgcggc catctcactc atttcgtgga
    21961 tctcaaaacc atatcctcct gggtcaaacg ttgggggctg attgcacagc tcaatgagtt
    22021 tttctttata tctctcactg ccaccatatt ttccgatcag tcctgaaaaa tcgtgataaa
    22081 cagcaaagct gctttgccaa gcacttcctt ctgcataatc ttgtccccaa cgattagctg
    22141 aaaatggttc tctgaacttg ccatctttat cttttgaacg cataaatcct gactcatagt
    22201 caaagatatt ttgatagttc aatgattgct gctgatattt cttcgtcatt tcctcttctt
    22261 ctagtacctt ggcaacttgg ctaatacaaa aatcgctata agcatagtct aatgtgtgat
    22321 tgactgattc gtggtagtga ttaggaacat agccatatgt caagtaatct tctgttcctt
    22381 ggcgtccata atttggatgt ttgctttgaa ccgtagcacc tttttccatt gccgttagaa
    22441 attcaggcat caagtctcgt cggatatctt ttacagcagc atctgcaatg accgcatcga
    22501 tcaatgtccc aggcataagt ccacgttcat caggagacag ccattttggc aaatagccac
    22561 tttctctata gctgttcaaa aaaccttcca gcatttcttc gtatttttct acagcaatca
    22621 aagaataaag aggataaacc gttttatacg tatcccaaaa cccattattt gtatagagaa
    22681 caccaggttt tatagatcga ctagtcgtat catagtggat tttttgccca ctaggatcaa
    22741 tttcataaaa tgtttgtgga aataaaaaca cccgatataa attatgataa aacgtccgca
    22801 attgttgttg atcatggtgt gtgagctgta tacgatcaaa ataggactgc cattgttctt
    22861 gactgtgagc aaggtaagtc tctttgcttt ggttttgttc tagttccagg ttataagctg
    22921 cttgttccga gctgataaaa gatgtcccaa atcggatagt ttgttttttt gtctgttcaa
    22981 aatacaacgg gatcgagtcg ctatttttgt tggaaacagc taactcatca attgttaaag
    23041 gatattcaaa tctcaatata aaataaaaag aaaaatcagg atcttctgaa ccagcaaaat
    23101 gtgtgatttt tccttccact gtgtaaggat ctataacaaa gagctgatgg cgtcccggaa
    23161 aggataaaag taaaccgctg tcatttttgc tgtaatcaat agataagatt ccgccataca
    23221 tgctaggtat caatgtagaa cagatgccat aacgtaattg acagatcgac agatgagtcg
    23281 ggcaaaatat actttcttct gggcggtaag aactttgagc atggaaaagg gtgttctcct
    23341 gtagttttcc attgatcggc gtaaacagca tatgactgaa atcacccatc caaggacttg
    23401 gttgatgggt aagacggtag ccttgaaaaa cgcggtcatc aggatgaaac caccagctgc
    23461 cgttttgatc cgtagtttgc ggtgcaaaat aattcatccc aaaaggaacg ccagtataag
    23521 gctggcagtt cccattagag aaatttggct gattcgctgt tgcatgtcta gtatctattt
    23581 gaccgatatt cattttattt ctcctttgtt gattgtcttt tgatgaatga aactggaaat
    23641 ttactatcgg atggtcgatc ttttgtctct aaccaagtga ccaaagcatc tcccgcaagc
    23701 ttacctaact gttcaaaatc ttgtgcgatg gttgtcagtg gcgggtcaac aagagctgct
    23761 gcttggatat catcaaatcc gataattgaa aaatcttcag ggatatgata accatgctgt
    23821 ctcaagagat tcatggtctg gatagcgaca acatcgtttt cacaaacaaa agcagttact
    23881 tcatacttag tgatataaga aagcaattca tctaatgtcg cgcttttgtc atccagtgaa
    23941 gtgtggaaag tcaaaccagc tttgtccaat gcttcaaggt aaccaaggta acgctgtcga
    24001 acggattgtg gatgagtctg cgtaccaaac aaataagcga tttttgaatg tccctgttcg
    24061 atcaaataag aggcagcaag cgcaccgcct tggaaattat cggaaagaac ggtaggaaaa
    24121 ggtaactcat agattttttt atctaatatg acgacaggga attctttcaa tgaaagctca
    24181 aaaagtaagt caagatgttg ttctgtatca agagcataat aaatcaatcc gtcaaattca
    24241 ttgattagct cttttgctgt tttattttgt agaaagtcaa gcgtcgtcat catgacatca
    24301 atctgtttat cttgcatcac agggttcaat cccttgctaa aatcaccaac agacaaatca
    24361 gcgacatatg gaagaagaaa cagaatccgt cgtgtttttg taggagaagc aagaatctgt
    24421 tccggagaag cggatttaac gaaactgcct ttcccgcgaa cgcgataaat aagtcctaat
    24481 tgctctaatt cagtcaatgc acgtttggaa gtgattctgc ttactttata ggtacgtgaa
    24541 agttcttttt cagttggtag ttggctgtct acaggtaatt caccagttaa aatagccgtt
    24601 tgcaaatcat taaatattgt ctggtacaat ggttgagtca tataaacacc tcttaatgat
    24661 atatcatatt caaataatac cataatggat gaaaaagtaa ataaaaagat attttttgaa
    24721 agcgtagaca taattggctg tatgaagtat aatctttaaa gatatatcaa atagaaagaa
    24781 ggttttatta gtggtttata aagatatacc aaaatcggtg cagaaattta tggaagatat
    24841 cacacaaaaa tgtggggata tccatgcgga ctgggcaaag aattttacag cagcatttgc
    24901 caatactctg ttgacaacag tcaaaaagca aaatgacgga accacctttt tattgacggg
    24961 agacattcca gcgatgtggt taagagactc tactgcacaa gttcgtcctt atttagtgat
    25021 tgcaaaagaa gatgaggaat tagctgacat gatcagcggg ttagtcaaaa agcaattttt
    25081 ttatatcaat atcgatccat atgcgaatgc cttcaacgaa gaagctaacg gtgctggcca
    25141 ccaaacagat catacaaaaa tgaacgattg gatctgggaa agaaaatatg aaattgattc
    25201 tttatgctac ccaatacagt tggcctatct tctttacaaa aatacaggaa aaactgatca
    25261 attcaatcaa tcttttattg aaggtatcaa aaaaatcttg gacgtgttca aaacagagca
    25321 agatcatgaa cactctcctt atacatttgt acgagacacg acaagaaaag aagatacgct
    25381 gatcaatgac gggcgaggtg caaaaacagc ttttacagga atgacatggt ctggtttccg
    25441 tcctagcgat gatgcttgcc gttatggata tctggtacca tccaatatgt ttgcggtggt
    25501 cgtgttaggt tatgtggaag aaatttttca aacgatactc gatgataaag aaattgtaca
    25561 gcaaacacag aaattgaaga aagagatcca agaggggatt cagaatcacg gacgaacggt
    25621 taatcaaaaa gggcaaacga tttatgcata tgaagtagat ggaatgggaa acgccacagt
    25681 catggatgac agtaatgtgc ccaatctgat cgccgcacct tacttgggat attgttctga
    25741 acaagaggaa gattatctgc aaacaagaag aacattgttg agtaaagaaa atccatattt
    25801 ctatgaagga aagtacgcaa aaggaattgg atcctcccat acgccagaaa aatacgtttg
    25861 gccgattgca ttagctatgg aaggaatgac aacgtcagac aaatctgaaa aagagcggat
    25921 attgaattta cttgtagcaa ctgacgcagg aacacacctt atgcacgaag gattcgatgt
    25981 gaacaatcct gaaaattata cgagagaatg gttttcttgg gcaaatatga tgttttgcga
    26041 attagtcatg gattactttg atattagagt agaaaagtag gaggtatcgt aaatgaaaaa
    26101 gaaagtatat atcatttctc atagccactg ggatcgtgaa tggtacatgg cttacgaaca
    26161 gcatcacatg cgactgattg aattgataga cgatctacta gagctatttg aagttgatcc
    26221 gtccttcaac agttttcatt tggatgggca aacgattatt ttagatgact atcttcaagt
    26281 aaggccagaa aaaagacagg caatccaaca agcaatcaat gaaggaaaat tgagaattgg
    26341 accattttat atcttgcaag atgattttct tatcagctcg gaatcgaacg tgagaaatat
    26401 gctgattggc atggaagaaa gccgtaaatg gggaacccct gtcatgttag gctattttcc
    26461 cgatacattt ggaaatatgg gacagacgcc tcaattaatg aaacaagctg gtatttcagc
    26521 agcagcgttt ggccgtggtg taaaaccaat tggctttgat aatcaagttt tggaagcaga
    26581 aaactattct tcccaatact cagagatgtg gtggaaaggc cctgatcaaa cagcaatctt
    26641 tggtctgcta tttgccaatt ggtatagcaa cgggaatgag attccagtag aaaaagaagc
    26701 agctcttgcc ttttggaagc aaaaattagc ggatgcagaa caatatgcct ctacgaacca
    26761 cttattgatg atgaatggtg ttgatcatca accggtacaa aaagatatat caaaagcaat
    26821 ccatctcgca aatgaactgt ttccagatta cgagtttatt cattctaatt ttactgacta
    26881 tctggaagca gttcaaaaag atgtgccaga agacttaggc tcagtagaag gagaattgac
    26941 aagtcaagaa acggatggct ggtatacttt agccaataca gcatctgctc gggtttactt
    27001 aaaacaatgg aataccaagg tccagcgaca gctagaaaat attacagaac cacttgcgac
    27061 gatggcttat gaagttagtg gaaactatcc ccatgatcaa ttagattatg cttggaagac
    27121 attaatgcaa aatcatcctc acgacagtat ttgcggttgt tcagtcgatt ctgtccatcg
    27181 ggaaatgata cctcgttttg aaaaagcaga tgaagttgga aagtatcttg cacaagattc
    27241 cttagaacag ctgaccgcag caatcgatac gaccggattc ccaaaagaca gctttccatt
    27301 tgtcattgta aatactgcag gaatggataa aactggtgaa gcagaaataa ccatcgaatt
    27361 agaaagaaaa agattcgctg aaggaatacc tgaacaacta tatcaagagt tagaaaattt
    27421 gcctaaacgt aagtatcatg tagaaacaaa aagtggggcc actataccag ctattttatc
    27481 tgaagaaact gtccaatttg gttatgattt gccgaaagac cgtttccgtg tgccatatat
    27541 ggcaagaatg atcaaagtga ctttaccatt agaaaacatg ccagcatttt cttgggaaac
    27601 attcgcgctt gtagaagggg aagcgaaagc agaagaaaag gaaacaatga ttcatcagag
    27661 tggacgaatc atcgaaaacg gccctctaca tttgacgatt gaaaaaaatg gtaccattac
    27721 aatggaagat cgcaaaaaca aacgaaagtt gaataatctg catatttttg aagatatcgg
    27781 cgatatagga aatgagtata tctttaaaca acctttctgt gatcagccaa tcctatccag
    27841 taacaaagaa aactctgaag taaaagtatt agtagataca ccggaaatag caaaaataag
    27901 tattctacag gaaatggaaa tccctgtttc tgcagacgag cgtttagaaa aagaacagca
    27961 gatggttgtg gaatttcgtt atcgaaaagc agaacgatcc aaagaaaaac gaatccttca
    28021 aataaaaaca atcatgacaa tcagaaaaga tagtaaaaaa atcgactttg aaacgactct
    28081 cgacaatcag atgaaagatc atcgcttacg tgtcttgttt cctacaaagt tacatgtgga
    28141 acatcacgaa gcagatagta tttttgaagt ggtgaagcgc ccaaaccatg tgtctaaaag
    28201 ttgggaaaac cccacgaatc cgcaacatca gcaagcattt gtcaatattc atgatgaaga
    28261 gtacggtgta acagtcggaa actttggttt gaatgaatat gaagtaacag aagacggaca
    28321 aatcgcagtg acgctacttc gcagtgtggg agaactaggc gattggggat attttccaac
    28381 accagaagca cagtgtctag gtgagcatcg gttcaattac agcattgaac tacatggacc
    28441 agaagaaaaa ttctctactt atttgcatgc atacgcagca cagattcctt tttccactca
    28501 acaaatcaaa catcatgaag gaacattgat ttcaaaacaa caatatttaa cgataaaaag
    28561 tgaaacgttt gcaattacag ctttgaaacg cagcaagttt agtgataaag tagtagtaag
    28621 aggtttcaat atgtctagtc atttagaaaa attggaaata actaaagaca atggaaaaac
    28681 tgtcatattg aatctgcttg aagaaccaac gaagcaagcg gttgtcccaa taatccaacc
    28741 ttatgagatt cggacaatcg gattcgagga ggaaaacgaa tgtatggcgg aatagaagca
    28801 ggcggaacaa aatttgtgtg tgcggtttca gatggtggag aaattttaga aaaattaagt
    28861 atccctacca caacaccaga agaaacattg gatcaggtat ttgaattttt tgatcgttat
    28921 gaattgaagg gaatcgggat tggctcattc ggcccgattg gtatcgacaa aacaaaagat
    28981 aattacggat acgttttggc aactcccaaa aaagggtggg cacaattcga ttttcttggc
    29041 acaatcaagg aacgctacaa tattcctgct gcttggacaa cggatgtcaa tgctgctgca
    29101 tatggggaat tgaagcaagg agcagcacaa ggaaaaaata gttgtattta ccttaccgtg
    29161 ggaacaggaa tcggtgcagg tgtcgtgatc aatgaagaaa ttttttcagg gatcgcacat
    29221 cctgaaatgg gacatatttg ggtgaaacgc catccagatg accattatga aggtacttgt
    29281 ccttatcata aagattgttt agaaggatta gcagcaggac cgtctattga ggcacgcaca
    29341 gggatcaaag ggcaagatct gccgcaagat catcctgttt gggctattca ggcttattat
    29401 attgctcaag cactgatcaa ctatacgttg acgttagcac ctgaaaagat tattttaggc
    29461 ggtggggtaa tgaatcagga tcatctcctt caaaaaatcc gtcagcaatt tgttgaattg
    29521 atgggtggtt atatggaaac acctcaagta agtgaatata tcgttcgttg gggactgccg
    29581 aatgaaagtg ggattatcgg tagtttgctg ttagcagaac acgaacatca aaagtaagca
    29641 gacaaattac acaaaaagaa cagagtctta tcattatctg ctgataagac tctgttcttt
    29701 tttatttcta ttcccataat ccaggtaaag ctttaccgac tattttttct tgagtaaatg
    29761 gatggatcat gtgcagttct aatgcatgga gcatcagtcg ttcagctgtt ctattttggt
    29821 agagagggtc tccaacgatc ggatgtccct tatgagctaa atgaactctg atctggtgtg
    29881 tacgtccggt ttccaaaaca caatagactt gtgtttgttc agaaagtact ttgttgacag
    29941 tgacatgtgt caaggcgctc tgaccatttt tatcatctac gacccttttt ctccgatcat
    30001 ggcgatctcg tccaatttta ttggtgatgg tcatatcttt ggcaatttct ccccatacga
    30061 tggcttgata tctccgatag atcatttttt gttccaacat tcttccaagt atcggcaaga
    30121 caaatggatt ttttgcaaat aaaacggcac cgcttgtttc tttgtccaag cggtggacaa
    30181 cgtaaggtcg ttgctgttta gtgtcgagat aagcagctaa atgattgagt aaggtactgt
    30241 tttctgtcgg ttcatttgga tgagtcttca ttcctgcagg cttatccact ataatcaaat
    30301 gctcatcttc atataaaaca cggatgtgct tcgcatctcc taattgaact tcttgataat
    30361 tataatctgt ttcttcgaat aacaatgtga tctggtcatt gccctttact tcatgatgga
    30421 acaaagcagg ttgttgattg atccaaacgt ttttacgtat acgcaaaaag tgtcgaacct
    30481 ttctaggaac taaccattcc ttttcaagca agtcgcgaat tgttgtttca ggatggttca
    30541 taggtaaagt gatcgtgatt ttcacaagtg tactcctttc agtgcaattg cagactaatt
    30601 gtaccatttt taaaacatat ttaagaaaaa acttacattt ttctgttcat tcttatgtta
    30661 ctctacttgc actaacgtaa aaaaacatat tgaactacaa cttaagcagg aagaaaacac
    30721 tctttcacta tggtaaaata agacgattga atcaaataga caggagaaga agcaaatgga
    30781 ttttcaaagc attttagaaa agataaaagc tgctttgatc agtttttggc gttggatcag
    30841 accatatctc ggacaattcc atcgatggcg aaagcgcatc tggaaaaaat atcatgtgaa
    30901 caaattgatt ttgctgattg gtttgatctg tgtcttagtg acaagtatct acctctttat
    30961 tttagcaaaa caagcaaatg tcgaaacgtt aaaatcagga ttaagccaat cgacagtcat
    31021 ttatgataag aaaaacgaag aagctggcac actgtacgcc caaaaaggaa catatgtaga
    31081 attaaacgcg atttctccct atatccaaga tgcagtaatc tcgacagaag ataggaattt
    31141 ttacgagcat cacgggtttg atatcaaagg gattgcccgt gcagcagtcc gaatggtctt
    31201 gtctggcgga acatcagggg gcggaggaag tacgatcact cagcagcttg ccaaaaatgc
    31261 gtatctgaca ttagaccaaa cgtttgatcg aaaagcgaag gaattatttt tggcaatcga
    31321 gatcgaaaag aagtacagca aagaagaaat cttgaccatg tatcttaaca atgcctattt
    31381 tggcaacggg gtatggggtg tccaagacgc ttccagaaag tattttggag tagatgcaac
    31441 gaatgttacg ctgtctgagg ctgctacttt ggcaggaatg ctgaaaggtc ctggtattta
    31501 taatccgatc gatcacccaa aaaatgcgaa tgatcggaaa aacacagtac taagtgtaat
    31561 ggaagaaaac ggaaaaatca caaaagaaca agaacaagca gaaagccaga cagatatcag
    31621 cgcgtatctt aatgacacat acgataattc agattctggt tatcgttatc cttattattt
    31681 tgatgcagtg atcgatgaag cagttaacga gtatggtctt gatgaagaag atgtcatgaa
    31741 taaaggctat aaaatctata cagctttaga tcaggattat caaaagcaat tagaagctac
    31801 ttatcaaaac agtgcattat tcccagcaaa tgcttcagat ggtgccatgg tccaatctgc
    31861 ttcagtagct ttagatccga atacaggtgg tgtacaagca ctagtaggac gaagaggaga
    31921 tcatgtcttt agaggattca gctttgctac acagatgcgt cgttcaccag gatcaacgat
    31981 caaaccatta agcgtatata caccagcact ggaagctgga tacaagcctt ccagtatctt
    32041 gaaagacgaa ccgcaaagtt attacgatgc gcataatttt gacgggacat accaaggaga
    32101 agtaccgatg tatcaagctg ttgcacaaag tttgaatttg cctgctgtat ggcttttgca
    32161 tgagatcggt ttacaaaaag gatatgataa agcagaagaa ttcggcctgc ctttagcaaa
    32221 atctgataag tattatggct tagcccttgg tggactggaa aaaggagtat ctccattgat
    32281 catggcgggt gcttacagtg catttgccaa tgatggtcag atgtatacgc cgcatcttat
    32341 cacgaaaatc gttgattcga ctggagcggt gatcgtcgat aacacaaaca aaaaaccaaa
    32401 acaggtcata tcaaaggaaa cagccgatga aatgaccagc atgcttcttg gtacattttc
    32461 aaatggaaca gcggctgctg cgaatcctgc aggttatacg atagcaggga aaacaggaac
    32521 cacagaaact aatttcgatg ccacaaaagc aaatgaccaa tggatgatcg gttacacgcc
    32581 agacgtagtg atttcgacat ggatgggtta cgaagaatcc agcaagctgc actatttgga
    32641 agggacaagt ggaaatgttg tcgggaaagt cttcaaatca gcggcagaag gcatccttcc
    32701 gtatacttca aaaacaggat ttagtgtagc agatgcctat gccacaggag gacaagtggt
    32761 agctgcagat caagttggaa acacaggaaa ttctaatgga gagtctggaa attggcaaga
    32821 taacttgaat caatatggtg aacaagcaaa agaagggctg aaaaacttcg gcgatatggt
    32881 gaaagaaggc gttcagggaa ttggtgaagc ggctaaagac ctctggcgga aatatcaagg
    32941 agagtagccc ctttgaaaac gaataacccc atgttacaat agagagtaac tactaaaaga
    33001 aaagagggca taacatgtca aacatctacg atagcgcgaa tcaaatcgaa cgtgagatcc
    33061 gtgaattacc agaattcaaa gcgttgaaag aagcgtacga gaaagtacaa gcaaacgaag
    33121 aagcacacaa actgttcaaa gacttccaag cgatgcaaat cgaattacaa gaaaaacaaa
    33181 tgagtggaca agagttcagc gacgaagatg caatgaaagc acaagaaatg gctgtgaaaa
    33241 tccaatcaga agaagtaatc aatgacttga tgcaaaaaga gcaaggcttc agtacaatca
    33301 tcaatgactt gaaccgtatc atcatgacac cagttcgcga cctttacagc gaataaaact
    33361 attttatgaa acaacagagg gtgtgaaaga gacgttcggc cttgagcgat gacaaaattg
    33421 cttcttattg ccgataggct gtctcttgaa caccatttac caagaggtcg tgagcctacc
    33481 gtttaactct gagttacaag gaacaatttc aaaaaacagc ttctcatgtt tgatgactat
    33541 tgtgacttgt gaccgaggag ttggcaggag aacaccgttt attcagaaat aggagctacg
    33601 acaaaagtct tgtcatagct cctatttttt gtcattcatt tttcaagcgg tagaaatagc
    33661 ctttttgagc taacagtttt tcgtaagtac ctatttcaac gatttttcct tcatcgatca
    33721 caacgatttt atctgcctct ttgatcgttg aaagccgatg agccacaata aaagtagtgg
    33781 gtgtttctgt caggtaattc agggcttgct ggattttttt ctctgactgg ttatctaaag
    33841 ctgaggttgc ttcatctagc aaaatgattt ttggctgacg tatcaacgct cgtgcaatgg
    33901 agatacattg cttttggcca ccagacagct tgttgccatg ttcgcctact aaggtatcca
    33961 gaccatcagg aagctggtca atcagtgaag aaagttgcgc agcttcgatg acttcatcta
    34021 aacgttcttt tgatacgttt ttcaagccat aagtgatgtt ctctttgatc gaagcggaga
    34081 acaacaaagt ggtttgagga acaacggcta aataatttcg cacacttcgc atatccagtt
    34141 catccaaagg ctgatcatct agaaaaattt ttcctgaagt cggctggata aatccaatca
    34201 ataagttaag gagtgtagat tttccagagc cagatggccc aacaaaagca attgtttctc
    34261 cagctttcac ctctagagaa aaatgatcga taatcggttt gagtgagtcc ggataaagaa
    34321 aagaaacatc ctcaaaacga aaatttccat ccaaatgttg gatttttttc ttaccgtgat
    34381 aagtttctac atcgccagca atcaacagtt cgccaataga agtgatagat tccatgcctt
    34441 ttgaaatcgt aggaatcagc gtgatcattc cagaaacgga attgacgatc gtcgtgaaat
    34501 acgtctgata catcacgaca tcgccgggtt ggatgcgccc ttgtaaagct aatatcccag
    34561 tgaaaatcaa acaaatcagc tgaaatatct gaaaactagc ccagctgact gatccgaaaa
    34621 cagattgcag gatatctaag tggaatcctt tttcatagat ttgagtaaaa tgcttattta
    34681 agcgagttgt ttcgtgtttt tctaacccat gagctcgagc aatcggtgct aattcgatca
    34741 cttcgatcac ttttgcagaa gtctcttcca tttcttgcct gaagtctgag ttggactgtc
    34801 tgatcctttt acggaaaaag agagtaacga atgcggcgag aggaacagtc aataagaaaa
    34861 acatgaaaac aacaggactt ttataaagcg tgatacctaa agctacgaat aaattgacag
    34921 cgatatttaa tccgctgaca aatacttgag aggacaacgt ttggatagct tctacatcac
    34981 ggatgatctt tgactggatt cgtccagatt gcaattcttt ttgataagga atagatagtt
    35041 cttggatttt cttgataagg gtcgctctta gtccagcttc tacttgacgg atcgaagtgc
    35101 tatggtattt tacatgaaaa taattcgtca atatattttg accaatcaga caagccatca
    35161 aaaaagcgtt gaaataaatg gcctgcaact gagaagaatc tttcgatgaa gctgcattga
    35221 ttacattggc aatagcgatc ggcattaacc aagatggaag atgtttgata ataaaaaaga
    35281 gtcctgacat ggcaaaacgc caataatttc cctgataaag atgcagcaat gtctgaaaag
    35341 catttgcatg atatttttga taacttttct gtattcgttc ctccataatc ttctccttaa
    35401 caatcttggt aaataaactg caagtgttct attgcttcag gaacataaat ctcaggagta
    35461 gcttcaagag tggcgtacat tagaggacgc tcatatttga tataatgcag taccgggcgg
    35521 aaatctaaac agcccttgcc aacaggtacc atgcggatct ttccattttc catgatatag
    35581 tctttgagat gaagcgctgt aatataacca tgtaaattgt ccaaggcacc tcggatcact
    35641 ttttcctgat cagcatgatt ttctttatgc atcaaattcg cacaatctaa aatgattttt
    35701 aaatttggtg aagctacttc atcgattaaa cgtttagcta actgatagtt atagattgga
    35761 tgattgatcc ctgcttcaac agcaacagtt acgccaaaat tttctgcatg agcgactaat
    35821 tcaatgatag aatttctggc gatctgataa gcttcttcag taaaattttc ttttgtgtaa
    35881 ccgacagaga cactaccggt ttccgtagca atcatcttgg cttgataggc agagcacaga
    35941 gcaatttgct gtttgaaagt tgccaatgct tgtgcacgaa cttcttgatt tttgctggat
    36001 aggttgatat agcatcctaa aatggaaagt tcgatattgt ttttttggaa gtattcacca
    36061 aaataggcag cactcccaag tgtcatgtca gttaatttaa gttgttcagg aaatgctttt
    36121 tgtggtgcaa attggatatg ggacaagtga agctgtgata ctttttgaac gatttcttca
    36181 cgatttcgaa catctaaatc gtgggcacgg atgcctaaat ttaatggaaa catctcaaac
    36241 tcctttttgt aaataattag caagaggcag acgggattct tttatcaatt caacaattat
    36301 tcgggcaact ttatcagcgc cttctggact aaagtgggta ttgtctttta gtccttctgg
    36361 gtaattttta caagtatcag gcataagatg caggtagaat ttttttgtct cttcttttga
    36421 gaaggtctgg aacaattctt gtgatcttga gaacacatct aaaagaggaa tatggtgttt
    36481 ctcagcaaat gcacgcatcg cttttggata gtctccaagt atatctggat tcaatgttcc
    36541 gttttctaag taatctcgtc gcgtcacaga tgtcagtaag accatttgga cgttcgcttt
    36601 ttttgcgcat tcaaaaaata tctgcagatt ttttaaatag ctaccgaagg gaagcgtacc
    36661 tctttcttct tggattttct ggtcgttatg tccaaattgt acaaataaga aatcattcgg
    36721 ctgaaactgt gaagctagac gggctaacct tccttcctgg ataaatgatt tggtgctgcg
    36781 tccattcttt gcttggttat tgatctggat ctcgggtgaa aaataagcag agattttttc
    36841 tccccaacct gtctcgggac gcttgttttc atctttttct gccgcagtag aatcaccggc
    36901 aatatggata gtaggcatgt tatctcttct ttcataaagg tttataggca atgaagcaga
    36961 acagcaagag aagaagacgg agcaa
//
LOCUS       DACGDM010000020        34735 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.020, whole genome shotgun sequence.
ACCESSION   DACGDM010000020 DACGDM010000000
VERSION     DACGDM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.020"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            156..1862
                     /locus_tag="IXR05_001076"
     CDS             156..1862
                     /locus_tag="IXR05_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAQ4259614.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="IXR05_001077"
     CDS             complement(2020..2922)
                     /locus_tag="IXR05_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4259615.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3623)
                     /locus_tag="IXR05_001078"
     CDS             complement(2919..3623)
                     /locus_tag="IXR05_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAQ4259616.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="IXR05_001079"
     CDS             complement(3654..4295)
                     /locus_tag="IXR05_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4259617.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4602)
                     /locus_tag="IXR05_001080"
     CDS             complement(4333..4602)
                     /locus_tag="IXR05_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259618.1"
                     /translation="MSPESSIGIAKIQKLIARSIFSSGMKRNFYRDQFLIFLKFIFLR
                     LVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYLMI"
     gene            complement(4575..5264)
                     /locus_tag="IXR05_001081"
     CDS             complement(4575..5264)
                     /locus_tag="IXR05_001081"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAQ4259619.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQIEARLMKIEK
                     SDLCLQNHQLE"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IXR05_001082"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IXR05_001082"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAQ4259620.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="IXR05_001083"
     CDS             complement(5984..6916)
                     /locus_tag="IXR05_001083"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAQ4259621.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="IXR05_001084"
     CDS             complement(6913..7689)
                     /locus_tag="IXR05_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAQ4259622.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IXR05_001085"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IXR05_001085"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAQ4259623.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IXR05_001086"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IXR05_001086"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAQ4259624.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="IXR05_001087"
     CDS             complement(12014..13294)
                     /locus_tag="IXR05_001087"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAQ4259625.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="IXR05_001088"
     CDS             complement(13313..14239)
                     /locus_tag="IXR05_001088"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAQ4259626.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="IXR05_001089"
     CDS             complement(14252..15535)
                     /locus_tag="IXR05_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAQ4259627.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IXR05_001090"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IXR05_001090"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAQ4259628.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="IXR05_001091"
     CDS             complement(16323..17234)
                     /locus_tag="IXR05_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4259629.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="IXR05_001092"
     CDS             complement(17231..17695)
                     /locus_tag="IXR05_001092"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAQ4259630.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="IXR05_001093"
     CDS             complement(17700..18398)
                     /locus_tag="IXR05_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4259631.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="IXR05_001094"
     CDS             complement(18385..18771)
                     /locus_tag="IXR05_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259632.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="IXR05_001095"
     CDS             complement(18918..20588)
                     /locus_tag="IXR05_001095"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAQ4259633.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="IXR05_001096"
     CDS             20771..21004
                     /locus_tag="IXR05_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAQ4259634.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="IXR05_001097"
     CDS             complement(21103..21534)
                     /locus_tag="IXR05_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAQ4259635.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="IXR05_001098"
     CDS             21613..22026
                     /locus_tag="IXR05_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAQ4259636.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="IXR05_001099"
     CDS             complement(22064..23212)
                     /locus_tag="IXR05_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4259637.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="IXR05_001100"
     CDS             complement(23334..23930)
                     /locus_tag="IXR05_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4259638.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IXR05_001101"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IXR05_001101"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAQ4259639.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="IXR05_001102"
     CDS             27160..27591
                     /locus_tag="IXR05_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4259640.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="IXR05_001103"
     CDS             complement(27636..28985)
                     /locus_tag="IXR05_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4259641.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="IXR05_001104"
     CDS             complement(29055..30218)
                     /locus_tag="IXR05_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259642.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="IXR05_001105"
     CDS             30347..30670
                     /locus_tag="IXR05_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259643.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="IXR05_001106"
     CDS             complement(30853..32202)
                     /locus_tag="IXR05_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4259644.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="IXR05_001107"
     CDS             complement(32271..33224)
                     /locus_tag="IXR05_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAQ4259645.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="IXR05_001108"
     CDS             complement(33326..34516)
                     /locus_tag="IXR05_001108"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAQ4259646.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9869 a         7605 c         6096 g        11165 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttcaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaat ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggc
//
LOCUS       DACGDM010000021        34636 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.021, whole genome shotgun sequence.
ACCESSION   DACGDM010000021 DACGDM010000000
VERSION     DACGDM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.021"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            591..1280
                     /locus_tag="IXR05_001109"
     CDS             591..1280
                     /locus_tag="IXR05_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4259647.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="IXR05_001110"
     CDS             1267..2475
                     /locus_tag="IXR05_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4259648.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="IXR05_001111"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="IXR05_001111"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAQ4259649.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IXR05_001112"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IXR05_001112"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAQ4259650.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="IXR05_001113"
     CDS             complement(6578..7273)
                     /locus_tag="IXR05_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAQ4259651.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IXR05_001114"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IXR05_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAQ4259652.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="IXR05_001115"
     CDS             complement(8472..8663)
                     /locus_tag="IXR05_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAQ4259653.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="IXR05_001116"
     CDS             complement(8684..9574)
                     /locus_tag="IXR05_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAQ4259654.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="IXR05_001117"
     CDS             complement(9561..10328)
                     /locus_tag="IXR05_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4259655.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IXR05_001118"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IXR05_001118"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAQ4259656.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IXR05_001119"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IXR05_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAQ4259657.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IXR05_001120"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IXR05_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAQ4259658.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14944..15282
                     /locus_tag="IXR05_001121"
     CDS             14944..15282
                     /locus_tag="IXR05_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259659.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="IXR05_001122"
     CDS             complement(15450..16208)
                     /locus_tag="IXR05_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4259660.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="IXR05_001123"
     CDS             complement(16226..17044)
                     /locus_tag="IXR05_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4259661.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IXR05_001124"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IXR05_001124"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAQ4259662.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IXR05_001125"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IXR05_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAQ4259663.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="IXR05_001126"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="IXR05_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAQ4259664.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="IXR05_001127"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="IXR05_001127"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAQ4259665.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="IXR05_001128"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="IXR05_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAQ4259666.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="IXR05_001129"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="IXR05_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAQ4259667.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="IXR05_001130"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="IXR05_001130"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAQ4259668.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="IXR05_001131"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="IXR05_001131"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAQ4259669.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="IXR05_001132"
     CDS             27086..27385
                     /locus_tag="IXR05_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAQ4259670.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="IXR05_001133"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="IXR05_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4259671.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="IXR05_001134"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="IXR05_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAQ4259672.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="IXR05_001135"
     CDS             28352..30325
                     /locus_tag="IXR05_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAQ4259673.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="IXR05_001136"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="IXR05_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAQ4259674.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="IXR05_001137"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="IXR05_001137"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAQ4259675.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="IXR05_001138"
     CDS             33204..34496
                     /locus_tag="IXR05_001138"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAQ4259676.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10554 a         6733 c         6844 g        10505 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tatattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagac caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgttaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggattaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagactat gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat
    25441 atcgaacatc agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa
    25501 gcaagggcac acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag
    26881 aatgaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattggatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaac gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaacact gtttattcag aataagggac tgtgacaaaa accgtgtcac
    34621 agtccctttt tccgaa
//
LOCUS       DACGDM010000022        32176 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.022, whole genome shotgun sequence.
ACCESSION   DACGDM010000022 DACGDM010000000
VERSION     DACGDM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.022"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(24..203)
                     /locus_tag="IXR05_001139"
                     /pseudo
     CDS             complement(24..203)
                     /locus_tag="IXR05_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            complement(407..766)
                     /locus_tag="IXR05_001140"
     CDS             complement(407..766)
                     /locus_tag="IXR05_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAQ4259677.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(796..1137)
                     /locus_tag="IXR05_001141"
     CDS             complement(796..1137)
                     /locus_tag="IXR05_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259678.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(1134..1808)
                     /locus_tag="IXR05_001142"
     CDS             complement(1134..1808)
                     /locus_tag="IXR05_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4259679.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(2984..4282)
                     /gene="asnS"
                     /locus_tag="IXR05_001143"
     CDS             complement(2984..4282)
                     /gene="asnS"
                     /locus_tag="IXR05_001143"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAQ4259680.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(4322..5512)
                     /locus_tag="IXR05_001144"
     CDS             complement(4322..5512)
                     /locus_tag="IXR05_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4259681.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(5533..6060)
                     /locus_tag="IXR05_001145"
     CDS             complement(5533..6060)
                     /locus_tag="IXR05_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4259682.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(6107..8896)
                     /locus_tag="IXR05_001146"
     CDS             complement(6107..8896)
                     /locus_tag="IXR05_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4259683.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(9043..9243)
                     /locus_tag="IXR05_001147"
     CDS             complement(9043..9243)
                     /locus_tag="IXR05_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4259684.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(9696..10016)
                     /locus_tag="IXR05_001148"
     CDS             complement(9696..10016)
                     /locus_tag="IXR05_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259685.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(10519..11637)
                     /locus_tag="IXR05_001149"
     CDS             complement(10519..11637)
                     /locus_tag="IXR05_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259686.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            12108..13415
                     /locus_tag="IXR05_001150"
     CDS             12108..13415
                     /locus_tag="IXR05_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAQ4259687.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            13536..14735
                     /locus_tag="IXR05_001151"
     CDS             13536..14735
                     /locus_tag="IXR05_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4259688.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(14762..16030)
                     /locus_tag="IXR05_001152"
     CDS             complement(14762..16030)
                     /locus_tag="IXR05_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAQ4259689.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(16200..16841)
                     /locus_tag="IXR05_001153"
     CDS             complement(16200..16841)
                     /locus_tag="IXR05_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAQ4259690.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(17250..17753)
                     /locus_tag="IXR05_001154"
     CDS             complement(17250..17753)
                     /locus_tag="IXR05_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4259691.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(17876..18640)
                     /locus_tag="IXR05_001155"
     CDS             complement(17876..18640)
                     /locus_tag="IXR05_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAQ4259692.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            18748..19023
                     /locus_tag="IXR05_001156"
     CDS             18748..19023
                     /locus_tag="IXR05_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAQ4259693.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            19583..20533
                     /gene="yidC"
                     /locus_tag="IXR05_001157"
     CDS             19583..20533
                     /gene="yidC"
                     /locus_tag="IXR05_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4259694.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(20579..20980)
                     /locus_tag="IXR05_001158"
     CDS             complement(20579..20980)
                     /locus_tag="IXR05_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4259695.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(20994..21803)
                     /locus_tag="IXR05_001159"
     CDS             complement(20994..21803)
                     /locus_tag="IXR05_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4259696.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFVALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(21790..22680)
                     /locus_tag="IXR05_001160"
     CDS             complement(21790..22680)
                     /locus_tag="IXR05_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4259697.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            complement(22693..23172)
                     /locus_tag="IXR05_001161"
     CDS             complement(22693..23172)
                     /locus_tag="IXR05_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4259698.1"
                     /translation="MAIIGVRIDGRLIHGQVANLWTTKLNISRIMVVDDEVATNTIEK
                     SGLKLATPAGVKLSILPIEKAATNILAGKYDSQRVLIVAKKPDRILSLVEKGVPIKEV
                     NVGNMSQTNETRSITKSINVVDADIEVFKKLDQLGIHLIAQMVPNDKAEDFMNLLIK"
     gene            complement(23348..24289)
                     /locus_tag="IXR05_001162"
     CDS             complement(23348..24289)
                     /locus_tag="IXR05_001162"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HAQ4259699.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            complement(24286..25281)
                     /gene="lacD"
                     /locus_tag="IXR05_001163"
     CDS             complement(24286..25281)
                     /gene="lacD"
                     /locus_tag="IXR05_001163"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4259700.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            complement(25274..26470)
                     /locus_tag="IXR05_001164"
     CDS             complement(25274..26470)
                     /locus_tag="IXR05_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4259701.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            complement(26488..27216)
                     /locus_tag="IXR05_001165"
     CDS             complement(26488..27216)
                     /locus_tag="IXR05_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4259702.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            complement(27657..28631)
                     /gene="lacD"
                     /locus_tag="IXR05_001166"
     CDS             complement(27657..28631)
                     /gene="lacD"
                     /locus_tag="IXR05_001166"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4259703.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            complement(28628..29086)
                     /locus_tag="IXR05_001167"
     CDS             complement(28628..29086)
                     /locus_tag="IXR05_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4259704.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            complement(29083..30546)
                     /locus_tag="IXR05_001168"
     CDS             complement(29083..30546)
                     /locus_tag="IXR05_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4259705.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            complement(30528..31460)
                     /gene="pfkB"
                     /locus_tag="IXR05_001169"
     CDS             complement(30528..31460)
                     /gene="pfkB"
                     /locus_tag="IXR05_001169"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAQ4259706.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            31602..>32176
                     /locus_tag="IXR05_001170"
     CDS             31602..>32176
                     /locus_tag="IXR05_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4259707.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFF"
BASE COUNT         9384 a         6920 c         5511 g        10361 t
ORIGIN      
        1 ttcttccata cagatgtttt ggcttattct ttctttttct cttcgatcat tgcccctgct
       61 cttatccaac ccgcacttgc cttcttgatc ttgacaggat agcaactaag tttgaagcct
      121 gttgctggca atttgtctaa attcattaat ttttcgatag gacaatatct tttttcaatc
      181 cctgcaaaat gtccttccca gatattcgaa gctccactac gctttcaaaa atatagaaag
      241 agttctttaa tgaaaattat ttcaactttc cataaacagt aatcccatat aaataaaaga
      301 cgtaaaagtc acatgggaga acttatacag gaaaacacat agagtcaggt gaaatacatg
      361 tatcccacct gactctatgc gttttctaac ctttattatt ctctttttat acaatttctg
      421 caccgaatgg catcaacgcc aatcgagcaa gtttgaaaga ttgcttggca aaaggtatcc
      481 ctatgatcgt gatacataga aggatgccgc tgacgacatg tgcgagagca attggtaggc
      541 ctgaaacgat cagccagatg atattaacga tcaatgacat gccagactgg tgataaatta
      601 cttctttgcc aaaaggcgca aaagaaaggg aggcgatctt aaaacattgc ataccgattg
      661 ggatacctat gatcgtgata caccaaagta tccccgctgc taaccagcta agaccaccga
      721 ttagtccgcc gaatataaac cagatgacat ttcctaaaca actcattgta tttctccttc
      781 tattactgtt tttgattaaa actgggcaaa aattgatttt attcttcttt ttttagcttc
      841 cagcatcaag tattctgcaa attttttttg gatttcttcc gtattttctt ttgttactaa
      901 tgtgtgttgg attagttttc ctgatggtcg ctgatccacc cgttcttctg actgttgcac
      961 gtccgcttgc gcaaatccga taatccgttt ttcttttgtt acagcaacga gcaatagttt
     1021 attcttatca tttaggtcag ctgccgtttt tgcttttacg aatgattctg gatgatcagt
     1081 aatcagctga ttgatttgag gtaaatcttc ttttactgcc caccgtattt ccatcatttc
     1141 tcacttttct ttcgctcatt tttatctcca ctaaaaaaat cgactgcggc aattgcatct
     1201 atccagcttt gtgcaatgat ctcatgtccg ccaatcgttg ggtggacccc atcttctctt
     1261 gtatatttcg aaaaaccata agcaatccct aaagcattga atatgccatc taaaggaacc
     1321 agcaatgcgc catattcctt agcaagttta cgaacaattt ggattttagg gtctaagtct
     1381 ttacgccagc catgacggtc gtcggttata ggaagtacaa acggctccat caagatgatg
     1441 ttgcagattt ccgctgtttg aagttcattt agtaattttc gataaacgga ttcaaattgc
     1501 tgcgcagatt tctcagttcc gaatatagcc tgatcgctag tattatgcca ggtatcattg
     1561 attccgatca aaatcgatac atagtcaggt tgtaaagcta aacaatcttc ttgccagcgt
     1621 acttgcagat ctgcaatttt gtctcctcct atcccacggt tcatgcattc aaatttcatc
     1681 gttggatatt gggagattag ttttccggca atcaaaagtg gataaccttt acctagatca
     1741 gttgcttctg ctcggtctct tcctgcgtct gtaatgctgt caccgataaa taatatacgt
     1801 tttttcattt gtcaaaaact cctttttgaa taaaacgatg attttcttcc ttatattatc
     1861 ccataagccc tatcaagacg aaagagaaaa tatatgtata aaaaatgaca ccagcctagt
     1921 cccttcaatc aattgaatga acgctcatca agtgtctagt tttttatact ttttttctta
     1981 acgtgccgga ttccccttga ttccttcgtt gtttggtcca gagaaatcga tcacacctaa
     2041 gcttccgtca atcagaccac tgatgacgcc atcagaacat atatttatag gctcatctaa
     2101 gacttccagt aaatgttctt ttactaatat ctcttctaga ttgcttggga tagattggtc
     2161 ataactttat ctggtccgat gatttcaagg atgaattaaa cttacatatg gatcattgca
     2221 tgctgaaaat acggacctac tccatcttcg aatgttacta ttagtttgtt ttcaggtact
     2281 agatgctgct ttatttcaac agcagaagca tcatcaaatc agatttccat ttgaataacc
     2341 ttctttgtat atgtttgatt gattgcgatt tcgttataga accttgtgaa tcaaatagca
     2401 atttcttttg ctttcttctc ttgtctgctg gaaacttcct ttatcccgta ttttaaaaaa
     2461 agaactgcga gagttcgcag ttcttttttt taaataaacg ttgctctccg gccaactcct
     2521 cggtcacaag tcacaatagt catcaaacat gaaaaactgt tttttgaaat tactccttgt
     2581 gactcggagc tgaacggcag gcgcacaacc tcttgatata aacggtgttc aatcagctga
     2641 ccctcgatat tagctaaaaa aacggtaaaa tatgagaagc tatttttccg ttttgtttct
     2701 ctaatactca ggtcaaggca ctgatttcac aacctcttcc ttaaacggtg ttcaaaagcc
     2761 agtttctcgg tattaagcca aatttatgca aaaatgtgga aagccatttc cacaaaattt
     2821 ttcttaatac tcgaaactaa acagcttttt cacaacctct ccactaaacg gtattcaaaa
     2881 gcttacatct gcggtaataa gtcccgccaa ttcaaaaaca tgaacagctg tttttgcttg
     2941 gctgttctaa ttacttgatg cagaacagct ttttcatcac ctcttatgga taaattcggt
     3001 tcaacaaacg tgggaatgga atagcttcac gtacatggtc gataccagca atccaagtga
     3061 ctgttcgttc aaggcctaga ccaaaaccag agtgcggaac agaaccgtat ttacgtagat
     3121 caagatacca tgaatattct ttttcatcca aaccgtgatt acggatttgt tctagcaaga
     3181 aatcatagtc tgttgcccgt tcgcttccgc caataatttc accgtaacct tctggtgcga
     3241 tcatatctgc acaaattacc acgtcttctc ttgttggatg tggtttcatg tagaatggct
     3301 tgatggcttt tggatagttt aggataaaga caggctgttc gaatgaattc gcaatgaacg
     3361 tttcatgagg tgaaccaaag tcttcgcccc attcgatgtc atcaaatcca tttttcttca
     3421 gtaattcgat tgcatcatcg taagtaatac gagggaatgg caattttgta taagttttta
     3481 agacttcttt gtctcgtcct agtacatcta atgcatattc gcaatgatct aaaacatttt
     3541 gtactaagaa tgctacatat tgttcctgta cttctaaact ttcttcttga tgagtgaaag
     3601 ccatttctgg ttcgatcatc cagaattcga tcaaatgacg tcgtgttttt gatttttcag
     3661 cacggaaagt cggaccgaat gaaaagactt ttccgaaagc catagcagca gcttccatgt
     3721 ataattggcc actttgagat aaataagctt tttgatcaaa gtaatttgtt tcgaatagat
     3781 ccgtagtgcc ttctggtgca gaaccagtca agatcggcgg atcaattttg acaaaatgat
     3841 gttgattaaa gaattcatac gttgcacgaa tgatttcatt tctgatctgc ataatcgcat
     3901 gttgtcttga agaacgcagc cataaatgac gatgatccat caagaagtct gttccgtgtt
     3961 cttttggtgt gatcggataa tcgtggctct cgcttaccac ttccacattt gtaattccga
     4021 tttcataacc aaattttgaa cgactgtctt cacggatttc tccagttact aacacggatg
     4081 tttcttggtg tagattttta gctgtttgga aaacttcttc cgacacttcg ctttttacaa
     4141 ctacaccttg gaaaaaggct gttccgtctc ttaattgtaa aaatgcgatt tttccgcttg
     4201 atcgcttatt tgcgacccaa gcgccgattg ttactgtttc tcccacatgg tttttcgaat
     4261 cgatgatttg aatttgttcc acgtatgact ctccttttat attccttgaa tttcttcagg
     4321 attaattttg acttttactc tcaataaatt gcttgattct gcgtaccgct tcttctaacg
     4381 tagcgcgatc agtggcataa ctcatgcgga cattttctgg tgccccaaag ccttcgccag
     4441 tcacaagcgc tacccctgtt tcttctaaaa gatcttctac ccattgtgtg acattttcat
     4501 acttacacat gcgtagcgtt tcttttacat taggaaaaag atagaaagct ccttgcggct
     4561 tttcaagaga aacacccggc agttctgcca caagcggata taacgtattc aggcgttctt
     4621 caaaggcgtt ccgcatttct tctactgtat cttgctcacc tttcaatgct tcaacagctg
     4681 catattgact gactgctgtc ggattgctag ttgattggga agcaacagcg atcattccat
     4741 tgatgatcac aggatttccc accgcataac caatgcgcca gcctgtcatc gcatatgttt
     4801 tagacacgcc gttgatgatg atggtctgat ttttgattgc ttctgaaatc gttgcaattg
     4861 gagtaaactc attgccatta taaactaaac ggccataaat atcatcagca actatcaaaa
     4921 tatcattttt tactgcccat tcaccgattg cctgcagttc attcttgcta taaatcattc
     4981 cagtcggatt cgatggagaa ttgatgatta cggcttttgt tttttctgaa cgtgcttgtt
     5041 ctagctgttc aacagtaact ttccagctat tggattcttc ccctttcaca aagacaggaa
     5101 gtccttctgc cagttttact tgctcaccgt aactgaccca gtaaggcaca ggaatgatga
     5161 cttcatcttg cgggtcaagg atcgtttgga aaagggtata caaagcaaat ttcgctccgt
     5221 ctgttacgac tgtttgtgaa ggttcataga caagtccata gtttttcttc agataatcaa
     5281 cgattgcctg tcgaagctct gggattcctg ctgttggtgt ataatagcta gctttcccat
     5341 tgcggattgc ttcgattgct gcttcttgga tgttttctgg tgtcgcaaaa tccggttctc
     5401 ccacagtcaa actcagcaca tctctgcctt ttgcttttaa tgccttggcc tttgccgcag
     5461 ctgccaaagt gacagacggt tctaatcgtt ttgttctttt tgataactcc atcccattca
     5521 ttcctttacc ttttaaattc ccttgattgt cttgacttca tctccagatt caaagccaat
     5581 caggtaataa ttcagtttcc catttgtttc ttttcctact acttcccaca caggctgatc
     5641 atcatacatc cctaaagcag ctttttcgat ttggatttca ggatgggccg cagcaattgt
     5701 ctgttttgct tcgttttcag tcagtccctt tgtttgatcc aatactttta ctttttcacc
     5761 agatttagga atgataacgg cgatttcttt tcctttatca tttgtacctg tcagtgaaaa
     5821 gtatgtcttc tttcgagtaa accaataaaa atgatcggtt tcctcaagat ttgcatattt
     5881 ctttgcgatt tctactgctt ctttcttcgc ctgcaccgcc ggacgactgg aacgcaagta
     5941 aaaaatcgag ctgatcacga tgaccgctaa taaaaatacg atcaagccaa gtaacacgcg
     6001 attaatcgtt ttttcctttg tctgtttttt cttcaagggt cgtcgctcct ttatcttcat
     6061 tccttttcat tatagcagat tttaattatg aaaaaagaca gctcctctaa cttccttctt
     6121 catttttctt taagaattca tggatatcct gatagatttc ctccatagct agctctttga
     6181 tcggtacttt tttcggtaat gcatggatga tccgtgcgcc atattttgca gtgactagtc
     6241 ttcgatccaa aataagcaat acgccacgat ctgtctccgt ccttatcaag cgacctaatg
     6301 cttggcgtaa cttcaaagct gctttaggta cggattcctg gtaaaaagga ttgatcccct
     6361 ctgattctaa ataagcgttc ctagctttga ccatcgggcg aagcggatta tcgaagggta
     6421 aacgtgtgac tacaacgatc tgcaaagcat ctccaggcaa atctacacct tcccaaaagc
     6481 tgtcagcgcc aaacaatacg cttttttctg acaaaatgaa gcgtttcaaa agcttctccc
     6541 ggcttccacc aaacccttga gctagtattt ctcgtccttt ttctagcata gacagatgca
     6601 ttttctgata gaccttctgc aaaacatcat gagaagtgaa taacacaagt attggccgat
     6661 cttcttgttc gatcagacct gtaagtgctg tctctaaata atcgatatat gcttgattgc
     6721 tgacttgatg gacggcaggt gcctcttttg gcacatagat ccttgcctgt ttctcataat
     6781 cataaggaga ggcaatcact ttaagaggtg ctgcttcaat gccaagcctc ttagagagat
     6841 agtgtcgatt agggccgatc ttcagcgttc ctccaatata aagaatacga tcatatcgag
     6901 gataccaaac agtcgacggc aacatagccg cttgaaaatc atggagatga aaaatcatct
     6961 gctgcgctgt gttcccagga acgaaccaat ggatcaaatg atctcgccag tcttccagcc
     7021 attgatccat cagcaagtat tgcttgtcta attgatcaaa taggctatat aaacttgcta
     7081 aatcgatccg catctggttt gtccagcttt cttggataat ctcaaaagtc agacgcattt
     7141 gtgactgtag ctgctggatc tcctgataaa aaagctgcag gtgatcaatg gctgtcccag
     7201 attccagtgg cagctgatcc aacatctctt ttgtcatcat gacttcttct ggatactgtc
     7261 cgttaggttg cttgccgctc actaaactca ttaatccttc tgccatacaa atctgtgctt
     7321 cgcatagcgc agaaagttct tctcgataaa tcgataacca gcgtaaggct tcatgttctt
     7381 tcggtaaata gctttgtatt cggtcaaaca gctgatttgg ttcttctaat tgctggattt
     7441 gtttatggaa atagttaata cttaatcgtt tgtcatttac tttttcagcg atttccggca
     7501 aatgatgtac ttcatcgatc aacaaaaatg gactagctgg aagcaatggt tcttttcgct
     7561 gtgtttcttg tactaaaaac gcatgattga caatcaaaaa attactttgc ctgattttct
     7621 tttgcaagaa acgaacaaag tcttgttcgt aaaatgactg atttcttgct aaaaatccaa
     7681 tacctctgtg cgcgatatct gcaaagaatg aatggttcaa atttgttaaa tgtaattcat
     7741 ccaaatcacc agtcttcgtt tgcgtcagcc aaactaagac cgccatttga tacaaagcat
     7801 attgtttttg ttctggcggt tccacaagtg tgcctttaaa acgctgcaaa tcaatatagt
     7861 ggcgatagct tttgataatt acaggttgta tgggctgatc tagcaattga ttcagcaatg
     7921 gaatgtcttt ttctatgatc tgctgctgca aaactagcga aacggtactg atgacagcgg
     7981 gtttttcagg tgtagccaaa taactcaatg gcagcagata accgattgtt ttacccattc
     8041 ctgtagctgc ttcgatcatc aaatcttttg attcatcttt tgtgaaatgg tcgtagaccg
     8101 cattcatcag tctgttctgt tcttttcgat acatcagtgt tttaccaaac attttttctt
     8161 ttgcttgttt ttttcttgga tatgtccgct cgccataatg gacggatgtg aatagttcca
     8221 cttctttttt ctgcaaagct agcccatcga cgatttctaa tgagggatca agtggctctg
     8281 gtttttcttt catttcttca atcacatgat aaatgaaacg actcgtatcc atacctgtgt
     8341 gtctacttaa tcgcgcaatc tgctctaacg tgatgattgg caattttctc atccgttctt
     8401 cgatcagcaa aagaagttga cctgtcactt cggcatcact atctgcctga tgaggattct
     8461 catgaataaa tccaaggctt tctgacaaat cagctaagcg aaagcttggt tccgtcggca
     8521 agaaaatttg tgcaagttct actgtatcga tgcctggtat cttcaaacta ggaagtccgc
     8581 atcgcatgag ttcatggttc aaaaaattat aatcaaaata aatattatgc gcgacaaata
     8641 tggtgtctgc caaaagattg taaatcgttt gggcgacatc ttcgaaataa ggcgcttttt
     8701 ggacgcgttg attcgtgatc cctgttaaat gctggatttg ttttgaaatc ttccgccctg
     8761 gatgaatatc gatcgaaaaa cgtgaagtga tccgacctga ttcaatcatg acgcagccaa
     8821 attggatgat ccgatcttct tttggattcg tcccagtcgt ttcgatatca acgactgcat
     8881 aagttcttgg tttcaaaata tcttcctctt ctcctgcctc taatgttctt ttgaaattat
     8941 actacaaagt gcagaaaaat actctcatcg ctttttaaag aaaatagaca aaaacgccca
     9001 gacacgcaaa tgtctgggcg tttatttttt agtataggtt aattaagctt tagtaacgtt
     9061 tgttgcttga ggtccgcgtt ggccttcttc aacatcgaaa gttactgctt ggccttcttc
     9121 taaagttttg aatccgtcgc cttggatagc tgagaaatga acgaatacat cgtttccgtt
     9181 ttctgcagtg atgaatccaa atcctttttc tgagttaaac cattttactg tacctgtttc
     9241 cataataaaa atcctccttg tgtatcaaca catattttgc aattacttga atggtgtata
     9301 tctggaagat gtttatttga aacaagctac cacagattac cgaacaaaaa ctactcctat
     9361 agtatatcat accgtttaca aaaaagctag agtttttcga ctttttttat taaaaaaagt
     9421 tttctcagcg attacataaa gtgaaaaacc gaactttttt ttaaaataaa cgacatattg
     9481 ttcagttggt gtttttttgc tctgatgttc ttttttaaac taaaaaaatt attctttctg
     9541 actacttatc ggttctgttt caacggtcga ggctggggaa gattctttag taggtctgat
     9601 gttctcatgg tatttctgat agcctatgac agttaccaga agaacaaggc aaaccaatac
     9661 gaccaacgag attagttttt cttttttgct catatctata cctcataaat aacaggatga
     9721 tgtccatcat atttctgagt atgagtaaaa gcaaaagctg cagctgtaga atgtaagaaa
     9781 tgccagcaac tttcataatc acaggtcgga cagtaccaaa agtaaccaaa tcttggctgc
     9841 aaagaccgtt cttctgtttc aggaatcgca gaatcaagat ctggtgtctg tacataaaca
     9901 tttttgtaca gacgtgtgcc tgtaatagga aaccgctgtg tttcttcagc aaaaactggc
     9961 tgacttgtta aacttaggga tagagacagc aaacaccata acagtctttt tttcataaag
    10021 acctccttat cgataagttt ttcccaatta aaatcatatc tcaagaacgc ccgttattca
    10081 cattttgttc ataaatgatg ttttttgtat cataatcgtc aaaaagaggt cgtgaccacg
    10141 tcacaacctc ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt
    10201 tcacaaaaat ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact
    10261 tctgtcacaa cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca
    10321 ccaaacaaaa aatatgaaga gctatttttg cttgctgttc ttattacttg atgcagaaca
    10381 gctttttcac aacctctcat acacggtgtt taatcagctg accttcggta ttagctcaaa
    10441 aaacggcaaa atatgtgaaa ctatttttcc gtttgtttct ctaatactca ggtcaaaaca
    10501 ctgatttcac aacctctttt aataacgaag aatcgctgtc agactctttt catctggcgc
    10561 atctttttga tccaaaataa acacttttcc gccattaatg atcacatcat ctgctaatgc
    10621 attcaacact tgacgccgat catattctgt ttcaggatct tcaccgaaac catcagctaa
    10681 gtttgacgta gcgataaata aatgtgacac ttttccttct ttcgcagctg gaacgatatc
    10741 aactaactga tcgatgaatt tcttatctaa gagtttattg tattcttttg attcttgagc
    10801 tgcgagttca cttgacagct tcttcgcccc ttcttcgata tctctaaagg atagctgcgc
    10861 aggagaagca gaaatcgcaa cgtctgcaca ataataggga tttttagcaa tttttttgaa
    10921 catcgtctga ttttctggta gagcaaataa ataaatcggc cattgttctg gattttcgaa
    10981 agaatccttc aagtacgtat caactgcttg gtaatagttg acccaatcga tctctacttc
    11041 ttcatctttt ggatttacgc catggaaagt tactccatct cgggctccgc ctcctccatt
    11101 agaagagaag ttcaaaccgc cacctgtcag ttcagatccc aatgcagtaa cgacatcaac
    11161 cggtgcccct tctggtagag atacttcttt tacttgtttg ttgctgactt catacaattt
    11221 catggagtcg cggttcaatc ccaataaata ataagaatag ttgaactgcc catttttgat
    11281 aatagccagt aaataaggaa gatcacttac atagtattga tcgtctaccg ggatactcaa
    11341 acgatggata taggtttggt cagcagttat aatgaccgct acactcgtag ttgcactacg
    11401 ccaaaacgaa ggatctccta acaaattttc aattttttct tggaacgggg accagtcatg
    11461 ttcggaatat tttttctcaa aacgtttctt tgcttctttc gcaaaatttt tgaatttgat
    11521 ctgatctttt tccacatctt gatgggcgac atgcgtattc agcatgatcg tgacgaatgg
    11581 tcctttagcg ccttctgaag tcaattgtga caataattct ttatcctttt ttgccataaa
    11641 cgtacccctc ctaaaaaaat cattcctttg tttctatcta aagtctacca caacactatt
    11701 tttccataca ataaaacgta tctaaaaaaa taaaacggtt tctacggttt taaatttagc
    11761 tattttttta agttatcttc ataatttcct caattattta gccccagtct tcaactattc
    11821 ttcatgaaat gctgataaac taagaaaaag aataaaagag gtggatctta tgcatttgat
    11881 tatgattttc agtttattaa gtattatcag tttatttgct ttcagcgctt cccgcttatt
    11941 agatgcggaa acacagccta ttcctgtaaa agtacgtaaa aacgaccgct aaccttccat
    12001 aacgtgcgtt cttatcctaa agttttttca gaaacattga aactctctcc cctctctgat
    12061 aaaattttaa tttgtagcga aacaaattaa ttacaaggag atcggatatg tccataaaaa
    12121 aaacacgtct agtcctatta ttggctagtc tcattctttg ccttgcttct tttctaccag
    12181 ctgttgctgt gcaagctgaa gatactttca aagtaaatgc aaaagcagcc tttgctgtag
    12241 atgcgcaaag cggtaagatt ctttatgatc aagatggaga aaaaaccatg gggatcgctt
    12301 caatcacaaa aatcatcggt ctttacatcg tccttgatca agtaaaagaa gggaaactat
    12361 catgggatga taaagtttca atttcagatt atgcagaaaa tttgagtgtc accccagatt
    12421 tatcaaatgt tcctttgcat aaagaaaaca cctacaccgt taaagaatta ttcgactctg
    12481 caatcatcca gtcagccaac gcttcaatgg ttgccttggc agaaaaaatc tctggcagcg
    12541 aagcaaaatt cactgaacga atgaaagaac aattgaaaga ttggggtatc aaagatgcaa
    12601 cgatcgttaa tgcatcagga ctgaataact cttatcttgg cgaaaaccga ccagaaggta
    12661 ctggagaaaa cgacgaaaat caaatgtctg ctcaagatgt ggctatcgtt gcccgtcatt
    12721 tgatcttgga ttttccagaa atactggatg tatctagcac tacgacacaa atgtttggcg
    12781 aaaacacgca atcaccagta gaaatggtca actggaactg gatgctccca ggattcgtga
    12841 attataaaga aggcgtggac ggattaaaaa ctggtacgac tgaacttgca ggagcctgtt
    12901 tcgtcggtac gatcactaaa aacgatcaac gaatcatcac tgtcgtattg aatgcagacg
    12961 gccatgcgga aaacccaagt gcccgtttca atgaaacagc tcgcttaatg gattattgct
    13021 acgacaattg gtcagaaaaa gagcttggaa aagccaatgc aagtatccct agtctaaaaa
    13081 ccattgatgt aaaagacgga aaagaatcaa cagtgcccgt tgtgcttaaa agtcctgtaa
    13141 aagtatgggt acggaacgat atggatactg gaaaattaac aatcacacca actcttgaca
    13201 aaaaacaagt cactgacaat gagatccaag cacctatgga taaaggaaca aaaatcggta
    13261 ccgcaacgat caccttggca gaagataaat taggttatct tgaagacaac aacgcgccat
    13321 ccacagaaat catcacggat aaaaccgtag aaaaagcaaa tattttcgtt attggctggc
    13381 gacgcgtcgc agaatttttc ggtaacttgt tttaattgaa caaaaagaaa aaagcatctt
    13441 tccatgtgga agatgttttt ttgctttttc tagtttaaat aacagctttt ttcatctatt
    13501 ttcgttatac tgtataagaa aaaggagttg aatttatgaa tctaaccaga gatctgattt
    13561 ttttggttct ctatcttatt ggggtattct ccatcgttta ttggcgaaaa cagaaaaagg
    13621 atccttcctt gttcttttac agcagtacat ggacgtttgc ggtaatcttg acttattttg
    13681 tcgtgttgga aattttttat tcgacctttt attttttgat tcccttagtg tttttcagta
    13741 tctttgcctt ttcctatttt tcagaaaagc gaaggctgtt gaatggtctt ttattcaata
    13801 ttttcctcat tagttttggt atctacttgt ttgtcttgct atacgaaaca caaaatattt
    13861 ttcttggcgg actgattgcc ttgatcacga tcccgttact gcttgtcttt ctattcggca
    13921 tttatggatt gatcgttttt cttttttgga acggtgtcac agttttacgt agagagtcgc
    13981 attcattagc taatctttta acgttgatac tagccatttt tcttacattg tttcttgttt
    14041 ttgacttttt cttgttaaaa tatttaccac aatggataaa tgctttgttt ttctgcatcc
    14101 cattgatctt gatctatcta tttatcgtat tctacaactt tttgactgtc tcattcttgt
    14161 atcagttcaa ccgccctcga tacaaccaag acttcatcgt tgtgttaggc gccgggttga
    14221 tcaatggaga aacagtttct cctcttcttg ccaagcgaat caataaggcg attgcttttt
    14281 attgggcaca aagccgtgcg acattaaatc cgcctatcct attaatgtcg ggtggacagg
    14341 gagcagacga aaaagtacca gaagcaatgg cgatgaaaca atatgccatg gaacaaggaa
    14401 ttcctgaaag agatattctt gtcgaaacca attcgacaac cactttggag aatatgcgct
    14461 attcaaagga aatcatggat cagcaaatga aaggtcccta tcgcgcgatc ttcagttcca
    14521 acaattacca cattttcaga gctggtctct atgcacgaca agcgaaactg aaggcaaatg
    14581 gcattggggc aaaaacagct ttctattact tgcctaacgc gtttttaaga gaatacatcg
    14641 ccatcttgat gatgaacaaa aaaagacata tgatcatttg cggattgctt ttcgcaggtt
    14701 ccgcattctt atcactgatc actttacttt tctaaaaaaa caaggtgtga caaaacatat
    14761 gtcacacctt gtttttttct tttattctct tgacgattgg caagaatagt attccttttt
    14821 tgacggctac ttgctgtgca gaataaatac cgctgtttcc tgaacacata aagctgatca
    14881 agcagatcat aaagaagtaa gcagcagctt gtgaaccaaa taattcgatt cccatcacaa
    14941 aacaggcaat cggtgtattt gtcgcaccag aaaatacccc gataaaacct aatccagcaa
    15001 gaaaaggaac agaaacatgg agcaaaggcg ctagtactgc gccaagcgtt gcaccaatct
    15061 caaatagtgg tgtcacttct cccccttggt accccgcacc taaagacaag accgtgaaga
    15121 ataatttccc aataaaatca taagcatgtg cctgtccatt aaatgattcc tgcagtaacg
    15181 gaagactcaa cccaaggtaa cgttgtgttt gcaaaatcaa cgctgcggct acaactactg
    15241 ctccacctat cgtatttcgc caaacaggat gaggaatcca ttgcgcatac cgcgctttta
    15301 aaaagacgat cgaacggctg aatacccaac caatcaaacc aaaagcaatc ccagcaacaa
    15361 aaactttgaa gaacagcaac atactccatt caggaatcac acccatttgg taatgtagat
    15421 gagaaacacc atagctttct gtcatgaaat ttgcaaaaag cgcagcaaag aagctaggaa
    15481 atattgcttc tgttcggact ttaccgattg ccaacacttc taatccaaat aatgttccag
    15541 ctaaaggtgt gccaaataca gaactaaaac ccgcactgat tccactgata accaaaatct
    15601 cccgttctgc tttatccaat cggaataaat gcgctatatt atcagctaat gctcccccca
    15661 tttgaactgc tgttccttca cgaccaacag atcccccaaa taaatgggta gtgatggtcc
    15721 caaacaaggt caatggaatg agccgcaaag ggatcttctc ttctcctcca ttcccttgat
    15781 cgatcactaa gttattccca cgactagaaa gaccgccatg atacgcataa agataagcaa
    15841 aaagcgcgcc gctgactggc aatagataaa gtagccaagg atgtgctagt cggatatctg
    15901 tcacgaacgt caggctattt aagaaaaaag cagacaagct ccccatgaat actccgagaa
    15961 tcgctgtgac caccagccac ttcaacatgt acatcaaaat acgcactgga ctcggtaatt
    16021 gtttttccat aaaaaattcc tcctcaaata aaaaaacgcc tactaaagaa aggggctggc
    16081 cccagacttt agtaggcgtc attagctatc ttacgttagc atttaaaggc gaacaccatc
    16141 acctattcac ttccattaaa agatagcata tttttctgta aaaaacaata aaattatcgt
    16201 tatttcttta cacgttcagc aaattcatag aaaggagcca atttcgttaa ctgttgatta
    16261 cattgatcac tatcatgaca aatataattc ccctttttcg tatacgtgcc atcagaaccg
    16321 gctttcgttg tagaaagaaa gagcgagaca ttcgatgttt tctgacagat cgcacagatt
    16381 cccttattaa tcgttggtga taaagtaccg ctgatccctt ttaattttcc atcttcgtaa
    16441 taaaccatga attttttttg cgtccctgga tcattccaac cgatgtacgt atgtgcttgc
    16501 aagtcgattt cattccaagc gggttgtttg agttttttca cttttcggaa taatttctcg
    16561 atttgtggtt tgctcggctg cataaacggc tggacgattt gcttcagctc ctccaatgct
    16621 cgttctgctt gcgtttttgt cagttttaca tctaaaactg tcgttaaaaa cgtatcgatt
    16681 tctgatggtt cgtaacctaa tacatcgcga atcttttcag ctgctagagc ctgaaccgtt
    16741 tgtaccgttt ttgagtcatt gacagatgag tacgcattta ataactgctc tacttctctt
    16801 tttataaaaa aatattgata tggtttcatt gtttgttcca tgattttaaa gtcctttctt
    16861 ctaaccaaag tgcatacttt gtagaaaaaa gtgatcttct gcaaagtatg tgttacctga
    16921 agatcccgga ctcttttaaa taagatacgt tttgcatctt atcatcaccc cctttaatgt
    16981 tcattcttct atgtacatga ttcattcgat aaataaaagt aaaccgtatc ttgagcagat
    17041 agtcaactgc aaacagaaaa aggactgtga caaaagtcgt gtcaaagtcc ctttctacaa
    17101 acaaacggtg ttccagaagt agcttcttca aaaaataagc cggaatttca caaaaatttg
    17161 agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gacccacttc tgtcacaacc
    17221 tcaatatggt ctattattgg ttttacctgt taaatcgagg attcttttcc gaagtaacgt
    17281 tgccatctct tacgcatact tgctgacata ggctgagcgg cttctttgac tgcgcagtat
    17341 ttgtctacga atgttacgat atatccttct ttgtacttag gcggtgcaat cgttgcgccc
    17401 cacatgtgct tcaaaatgat atctcgctca agatccgaca aatcggtgat cttttctgca
    17461 ttctttacag cgattcttgg atggatatac gcatgtgtgc cttcatcaaa tttcgtcgta
    17521 cgccaatcat agtagaacag atcatgcaaa agtccagcac gcgctgttgc tttagcattg
    17581 ccaccccatt tttttgcgag cagataacta tagtaagaaa cactgatgga atgctccaaa
    17641 cgagtggaat gaacatgctg tgtgtaattc gctaattttt tcactgcttc tgtttctaaa
    17701 agatcttcta cataagacat atattcttcg tcttcacgcc atttttctgt cataattatc
    17761 gatctgccac ctttttgaat ttcattttct tctgaaattg atctaagtat accaccagtg
    17821 ttcggattat tctagtcgcc ttggataaaa tagccaaagc ttaatagttc cttaatcata
    17881 aagaaaaatg ataaagaaca atccctgccg caaccccaac attcaacgat tccgcatttc
    17941 ctttcatcgg gatatatacg ttctgatcag tcaaagacaa gatttcctga cttaccccct
    18001 gaccttcgtt ccccatgatt attgcgaagt tatctgattt ttctactttg tctaaggcgt
    18061 gtgcttcttc atttaattct gtgccataca ctgtaaaccc tttgtctttc attaaaggaa
    18121 tcacttctgt caaatctttt tgcaacacag gcaaatgata attgcttccc tgcatgctgc
    18181 gcagcacctt tgtactataa atatctgccg ttcctttgcc taataaaaca ccagccatat
    18241 caaatgcatc tgccgtacgg atcatcgtcc ctacatttcc aggatcttgt acattatcta
    18301 ataacagcca tcctcctgaa aaatctggcg tgccttcagc cgttaacgcc atcactgcta
    18361 agattccttg tggtgtaggt agatccgata cagcatccat gacctcatcc gaaactagaa
    18421 aagtagaaat ctctttgttt gcggccagcc agtctcccca ttctttcatg cctcgctgtg
    18481 tcacaaaaag ttcttttatt tctgcatcag acgacgcagc ttcttcaatc agatggaacc
    18541 cttccaaaag atattcttcc ttttcttccc gatatttctt tttatgtagt ttttttaatt
    18601 ctttgattct tggatttttt gctgattgga tctctttcac attcctcacc tccccatgat
    18661 tatatcatgg aataggtgct tgagcttgtt tcatcctaaa aaaatcggta tcattaattt
    18721 ataaaatagg aaagaaaggt gacgaacatg cgcaaagtta aaatgaacgt ccaaggacgc
    18781 gtccaaggcg taggatttcg ctacatgacc aagatggtcg ctgatcaact aggcgtgact
    18841 ggaacggtaa aaaacgaaga tgacggctca gtcacgatcg aagcaatcgg caatgacgac
    18901 atcatccaga aatttattga agaagtcaag aaatctccga gcccaagtgg acgagtgcag
    18961 tatgtggatg tccaagaaga cccgatgatt gaggaacgaa agaaatttga tgtggtggga
    19021 taaggttgtg aaaaagctgg tctgcatcaa gcattaagga caggttgtga aaaatagctc
    19081 tccatatttt tcaacaggct ggacttaatg ccgtagatgc aagcttttga acaccgtcaa
    19141 taaggttgtg agaaagtcgc ttagttttga gtagtaagga gaattttgtg aaaatggctt
    19201 tccacatttt tgcataaaat ttgacttaat accgagaaac tgacttttga acaccgtcga
    19261 taaggttgtt tttgagacgc tttgcctcaa gtattaaaga taggtagtaa aaaagctgat
    19321 ctataacttg caataaattt gcttaaccca tattttccag acagaacaaa aaagttttta
    19381 gttttttaaa taagaaagaa acacttggaa tcactctttt ctttccaagt atttctttct
    19441 tgattttttg tctttttttc aaaatttttc gctacgtaaa agaacgaata tttatatgaa
    19501 atttctatga agttgattga attccatgcg cttttttagt atagttaagt ttgtgtaaaa
    19561 attatagaag aggaagtatt ctatgaataa atggaaaaac tggttattgg gatccggact
    19621 tgtcagtatc ctgctctttt tatctggctg tgtgcggatg gattcaaacg gaaaccctga
    19681 cacttcggga atcgtttatc gagtactcgt ccatcctatg ggccaagcga ttacatatct
    19741 agttgagaat ttcaattggt cttatggctg ggcagttatt gcaatgactg tgatcgtccg
    19801 tatcatcatc ttgccactag gtattagtca atcgaaaaaa acaatgatcc aatctgaaaa
    19861 aatgcaagcg ttaaaaccac aagttgaagc agcccaacaa aaattgaaag ctgcaacaac
    19921 acgtgaagaa caaatggcag cacaagcaga aatgcagcaa gtataccgcg aaaacggatt
    19981 gagtatgacc ggcggaatcg gctgtctgcc tctattgatc caaatgccga tcttctctgc
    20041 cttgtacttt acggcacgtt atacagaagg tattcgggaa tcatctttct acggcatcga
    20101 tttaggctca ccaagtatgg tacttgttgt cattgcaggg gtcgcctatc tgcttcaagg
    20161 atacatctca acgatcggta ttcctgaaga acagaaaaag acgatgcgta cgatgctaat
    20221 cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg ccagccggtg ttacacttta
    20281 ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc atcacaaacg ttatgatgaa
    20341 accacgtttg aaagcacaag tggcagaaga gttgaaacaa aacccgccaa aacaagtcgt
    20401 cactccaaga aaagacgtga cagaatcagc aaagccagct aacaacaaac aagcaacaaa
    20461 acaaatcaaa caaccaaaaa acagtacaaa caacaaaggc cgcaacgcag gaaagcagca
    20521 gaagcggaaa taaaaacata ggacaaaaaa gatgagagct aagccctcat cttttttgtt
    20581 actcttcctc ttctgctatt ccattaatta attcgttgac agagacaatg ctttcacatc
    20641 ctgcacgaac aaactcgggc tctgaaccaa tcatttgtga gttgataaat tcaatgacca
    20701 tcggaagatt catcccagca taaagagtaa tctgttgtcc ttccattatt agtttagaaa
    20761 tgatatttgc aggtgtacca cctaaaagat cgcatagtac cacaaaatca tttaacgaat
    20821 ctgtgacagt gagaaacttt tgtttgtatg tttcagtgcc atcttctggt aataaaggta
    20881 acgtgtagat atcctcttga ggccccatga tcatttctgt actttttttc aattcctcac
    20941 aaaattttcc gtgactaatc aataccaatt gtctactcat ttttcgctct cccttatttc
    21001 gaaatcacac ccaatgcaga taaagcaaca cacacaatta atacgataaa aatcgctcga
    21061 gtaggagtca tgtttttctt tcctaataac caataaacac caccgacgat cccagcaggt
    21121 aaaattttag gtaagatcat atcgatatag ttttgcatat tcaatgtcac atcgccaatc
    21181 gttggtgccc atgaaaattt aacattgatc attgtcgcaa ctaatgcccc taccatgaat
    21241 acccctaata aagtggctgc gtccgttaat gcagttaagc gagattgcat agtagtaact
    21301 aaggaaattc cttctttgta tgcaaattca agttgcttcc aacgaaaaac catgacaacg
    21361 atctgagcaa aaatccatat aaacacacct atcggatttc catcagttgc catattcgcc
    21421 gccaaagccc caaaaatcgt tggaatcaaa gcaacaaata cggaatctcc aatcgctgca
    21481 aaggaaccca tcaatccagc tttcagcccc gatacggttt cctttgaagc aattccctct
    21541 ttttcttcca ttgcaagatc aatcccagta atgattgtat taaaaaaatt agaagtatta
    21601 aaaaattgcg tatgtgtttt catcatctct tttaattctg gtgtattgtc tccatatatt
    21661 tttcttagtt gtggcaagat agtatataaa tagccagaac cctgcattct ctcatagttc
    21721 caacctaatt gaaaagtgaa caaacttctt cgattgattt gcttaaaatc ttcttttgtt
    21781 aatttgtaat tagatttcgt catcttcgat ttccccctca acagaatgtg atggctcact
    21841 agctaatggt tgatggtctt tgttttgatc attcttataa ctgatcattg ctagtgctag
    21901 accaatcaat gctacagcaa gcatcggcag cgaattgaaa gttgccggaa gatctttaac
    21961 aacgcttgcc acacttgttc ctaataattg aacattagag aataacgttg ctaataatgc
    22021 cgtgatcgta aatcctaaaa taagataaga tagatgtttt tttactggta aatagcgcag
    22081 aagaatggca aacccaacag ctggtaaaac agctcctgct actgaaagtc catcgcctag
    22141 ccattttaga ttcccgttta aaacagaaac aacattttca actaatccac caccaaatgc
    22201 taaagctaaa aatacaggaa tcatacgaga gagcgaccaa ggtaaagctc ccattaagaa
    22261 attgcgttcg attgcttgat aattcatgtc ttctacgtga cggtcaatac gatgggcaaa
    22321 gtatgtgtta gcgaatctag ctaaaatatc caattggatc attaagcttg ctacaggcac
    22381 tgcaatagca gcaatcgctt gttctggatt cattccaaga gaaatcgaga aggcagttgc
    22441 taaaatcgtc ccagagttgg catctatttt tgatgcgcct ccaaacgtcc ccactcctaa
    22501 aactgtcaac tgcatactgc caccaataat caaacctgcg tttaaatcac ccattactaa
    22561 acctgcatat aaccctgcaa acactggcgc actcattgaa gaatagatct gtaattcatc
    22621 taaaatttga taacctgcat ataatgttaa taataagatc tgccaccatt gaatatccat
    22681 ggatcattcc tcctatttga ttaaaagatt cataaagtct tctgctttat cgtttggtac
    22741 catttgagca attaaatgta taccaagctg atctaatttt ttaaatactt cgatatctgc
    22801 atctaccaca ttgattgatt ttgtaatgga ccgtgtttca ttcgtttgtg acatattccc
    22861 cacatttact tctttgatag gaactccttt ttctactaaa gataagattc gatctggctt
    22921 ttttgctacg atcaatactc gttgagagtc atatttgcca gctaaaatat ttgttgctgc
    22981 tttttcgatt ggcaaaatgc ttaattttac ccctgctgga gtcgctaact tcaatccact
    23041 tttttcaatt gtgtttgtgg ctacctcatc atccacgacc atgattcgac taatattcag
    23101 tttcgttgtc caaagatttg ctacttgtcc atgtatcaaa cgtccatcga ttcttacacc
    23161 aataattgcc atcatgcatt ctccttatct attttttcta tttattgttc aattaaaact
    23221 gtgacatcat caaatatccc ttctgtttca aagataacgt tttcattttt tctttcttat
    23281 atttcatttt taagctaaga acaaattcct tcccaactaa agaaaacgct ttcttttata
    23341 tttaagttca tttgattttc ttaacttgaa tgtgtttcat caacatcgta actttcatag
    23401 ggtcgatcca gccagttttc tcttgttgcg cgtttgccat accacaagcc atagaaaatg
    23461 cgagaatctc ttcgattgat tgcctttttg ataacgcatg ggccgatcct gcaagggtcg
    23521 cgtcacctga accaacagga ttaacaactg atattttagg aataatgact tcgtaaaaac
    23581 actgagcaac ttttgccaca gcacctctct ctcctaaaga aacaacaacc catggcactc
    23641 cttcaaatat tggatgagct aataaggact gaattttttc taattgaatc gaagaacaga
    23701 tacgttggcc aatcagttct cctaattctt ccagattggg cttgataagt agtggcttct
    23761 ccttaccttc caatacttca agcaaaaatt taccagaagt atctagtaat atgtctttcc
    23821 cttttttatc agctaaagca accaattgct tatagtaatc aagagggcat ccttggggta
    23881 aactacctga gatcgtcata atatctgata tttcgaggag ctgctcgaaa tgatcggtaa
    23941 atgtctgttg ttctttcttt gttatgaagg ggcctcgttc caaaagctct gtttgtctcg
    24001 aactatgcag gatagcaata gaatcccttg tctctccttt aattggaaca aactgatgca
    24061 tgatccctaa ctgatctagc tggttcttta gatattcacc gtgctggcca cctattaaac
    24121 cagtagctat cacctcttct cctaataaat ttagaaccct cgccacattc actccttttc
    24181 ctcccgctgt tttattgact gtttcaactc gattgacttt gtcgaggttt aattcttcaa
    24241 ttgtatacgc gatatcgatg gaaggattca aggtaactgt cgtaatcatt tcatcttcac
    24301 ctttttgctt tttgttttat tgaaccaagg ggtagcggtt tcatttatta ctttatttaa
    24361 agtctcgatg ttttctctcc catttgttct taaccaatga atagctccgt cttttccatt
    24421 ttcgacgtat gctttgaccc catctttcca tgtcgcacgt ccacacaata caccattgaa
    24481 ggtggaaccc gattcatgag caaaaatcag tgtttgttga aataattctg ttgaaacacc
    24541 cccactcaaa aaaatgaatg gtaatggagt cgcttcactt tgctccttaa agaaggcagc
    24601 agcctcttct ttgctgtgaa taaattcacc tgtggaatag ccattcacat aattcatatt
    24661 gactggtact tctactttca acacatcaac tttatatttt ggatcagaaa attctttcat
    24721 catctcaata actttgtggg gcttgacttt cgcatactct ggagaagaac tatcgcttat
    24781 ttgtgcatca taagaaacta actccaaata gaagggacga ttttctcctt cgcactcact
    24841 acctaaacgt tcgatgaaca catgcttcaa atgattgatt tcgggtgctt catcaacatc
    24901 gtagtaaagt aagaatttta ctgcatccgc ttgctgttct ttcaatctga gagaagacca
    24961 atccgctaat aaatcaggta gacgaccagg cgtagttgcg tcatagccgg ttttctcata
    25021 agctaacaat aaccccgtct cttttgctct gacttttgct gctggcaatc catattccgg
    25081 atccaataaa atagcagaag catagggtgt cagctcagct gatactagtt ctttgaattc
    25141 actgatttgg tcttcacttg gctcttttcc caacgatttg atcatttttt ttagagcacc
    25201 acgctgatcg atcgctaatg cactaataat cccatctttt gttgatagtc tctccattgc
    25261 cctatttttt tcttcattca tctgtcattt ctccttcggt ttcatactta tgaataatga
    25321 cgcccttgac tactcgattg accgtgcctg ttggagatgg tgtatctggt ttattagcta
    25381 ctttgattga agtatagagt gcaatgattt gtgcagtcat aatcatcgct aatgcaagat
    25441 aggcatcggg caatttactc accgagtctt ccaatagcac agtcatacct gagaaatcaa
    25501 tagtacccgg ttgcgcaatc gcaatgacat tggcagtgac ccgatcttct tttatttcct
    25561 ctaaaatatc taagtcataa tttcgcgtat atggttgatt gctcacaaaa cctacaacga
    25621 gtgtctcgct atttaaaaaa gactttggtc catgacgaaa ccccatcgaa gaatcaaaaa
    25681 ttgtagcaac tttacctgct gttaattcta aaatttttaa ttgtgcttct cttgtcgcac
    25741 ctgccaaact tcctgaaccc agataagcga tccgttcaaa aaaatcaggt aataactttt
    25801 gaatttcttg atctcttgaa agaagatctt gaccgatttt aactaattgt tcaagatatc
    25861 tttctttttt ctccattgct gtttgatcaa agatccataa agcactcaat aacatacacg
    25921 taaaacttcc tgtcatagca aaacctgcat cgtttgctct ctctggcatc aataacagat
    25981 aattctgttt atcatcctgt gcgttttttg ccaacatccc ctctttagca caagtaatcg
    26041 tcaaatgaaa caatgtttca acttgttcat ttgcaatttg cacagccgct acactttctg
    26101 gactgttgcc actgcgagca aatgaaacta ataaagtcgg ttcatttgga aacaaaaatt
    26161 cttttggtga agctacaata tctgtcgtgc caaaactgtg gaagataaaa aactgattgt
    26221 ctccatgttc atttagatag ggtaagagcg tatccccaat atattgagac gttcctgcac
    26281 ccgtaaaaat aacacgtatt cttcttccgt ttgcttcttt ttttatttga tcaaaaaata
    26341 gagctaaatt ttcttggctt tgcatcaatc tatcgattgt ttctttccag agatctggtt
    26401 gttgttttat ttcttgtgtc gtgattgctg cacctatttg ttttaatttg ttcttcgata
    26461 gctcaaacat gttgttctcc ctctcaatca ttttcggata tgccgaattt tataatgaaa
    26521 ctggtccgct cttgctacac tatctgtata ttcgataatc tcatttttca cgttataggt
    26581 tatcctcgtc agatgtaaga cgggagcgcc atcagcgatt cgtagcacaa cagcatcttt
    26641 tttttgcacg atacttgcat aaaactcttc atcagctaat tgaacttgtt gttcataatc
    26701 ctgtgaaaac acatcataca acggtttact ttcaagtaac ggcaaatcaa gtcccataaa
    26761 tagtttcgcc ggtagataag aacgctcaac catcaatggc tcttcatctg ccaaacgcaa
    26821 tcttttaagt ttaaatacag tttcacctaa atggatgttc aaattcttag caattctctt
    26881 attagcttcc atttgtctaa attctaaaat gaccgtctta gggacgcgcc ctatttcgcg
    26941 catttcttct gtaaagctat atgctccagc taagttcgat gacttatcag acaaatcaga
    27001 gacataggta ccttttccat gtcttcggta aatataacct tgattttcca attcctgtaa
    27061 agccagacgt acggtggtac gactcacccc atagtgttga caaagttctc tttcagataa
    27121 cagcttatca tgcggagtca tctgtgtttc gatacgatcc ttcaataaat caactagttg
    27181 ataatacaat gattttcctt tatttgagct ctccataaaa atcacctctt ctttactggt
    27241 tataaccaca acacaagaat agtgaattat taatcatttg tcaaaggttt tttagaccaa
    27301 aaaagctatt ataacagctc tttaaagctt tatatcttga atagacaaag atacctcaaa
    27361 aataccagtt accaataaaa gaacagaaaa aaagacgaac cacataagcg atccgtcaaa
    27421 atggtctaac ttatcgagca gcgtgatcca cattaatccc tatgatattc ctacaactat
    27481 cgttttatta cttccaatat catttacaac aactaaaaat agcttattaa tgacaaatgt
    27541 tattattagt tttagataac ttttgcagtt ttatactttt tttctataaa atttgacaaa
    27601 cattttttta aataactaat tattttttga atctgtcact cagacaatcc tttctcttac
    27661 ttgttaacat aaatagaagt tgctgtttct tctaatagtg tacttaattc tttaatattt
    27721 tgttttcctt cttctaacat ccaactactc gctttttctt cgccttcggt aacaaaaggt
    27781 gctactccct tcgcccatgt tgctcgccca cataagacac cattgaatgt cgaacctgat
    27841 tgttttgcaa aacgcaatgt atcttgaaat agtgcagcgc tgactcccgc acttaaaaaa
    27901 ataaacggtt gttcagtcac tttcgattgt tcatagaaat acgcggatgc ctctgcttga
    27961 ctataacaag tatcttgccc atatccttcc acaaatctca tattcactgg tacttctact
    28021 ttcaatacat ccacttgata acgttctttt gaaaattctc gcatggcttc aatcacttta
    28081 tgcggtttta cttttgcata gtcaagagaa gacggatcgc caatagttgc atcgtaagaa
    28141 aggagctcta aaaagaaagg tatgccttct gcttcgcatt ctgaaccaat ccgttctata
    28201 actatttgtt tttgcacatt aatctctact ggttcatcaa cgtcatagta caataaaaat
    28261 ttacaagcat ccgcacccac ttcttttaac cttttcactg accaactatt cagtaaatct
    28321 ggtagtcggc ctggcatttt cgcatcatag ccggtttttt cataagctag caacaaacca
    28381 cattctttct ctcgaagcgc tgctgcaggc agaccatatt ctggatcgag taaaatagcg
    28441 gaagcatacg gagtcaggta ctgagaaacc atctgtttaa attggatgat atcttctgat
    28501 gtagcttctt tatattggtt gatcattttc ttcaaagcac cacgttggtc gatagctagc
    28561 gcgctaataa ttccagcttc atccgtcaat cgcttcaaac gttcctgttt ttctatactc
    28621 attttcttca tatatcttca cctatttctt tagttaatat tgtagctatt tctatttttg
    28681 attttgcagc tctcaactgt tctgtaacct cttttcgcat caatgatcgt gcaacgagag
    28741 acaataattt caaatgagtc gttcctgctt ctgaatctgg gataaataac gcaaaaataa
    28801 aatcaactga ctgtctatct aaactgttcc attcaattcc ttttttcagt gtgacgataa
    28861 tcaaactagg ttcattgatt gtttgagact tcgcatgagg gatagcaaaa cctgacatta
    28921 ttcctgtagt accttctttt tctctttcca gaagtttttg atatacttct ttttcgtcat
    28981 gagcgattcc taaacagaat gtttgctttg ctaaaaactt aaatgcttct tcttgattat
    29041 ctaatggctg ttgtaaaaaa atgttctctt catgaatgat tgtcatgata aacctcctgc
    29101 tcttccttct tcgataactg tacgatttgt tgctttatta tccctcttct tgtctttatc
    29161 agttactctt ttcttttgga tcaaacctag tatcactcca ccaacgatcg aaccaataag
    29221 aatcgctgta acccattgga tttttcccgt cactacaggt aacactaaaa aaccgccatg
    29281 tggggctggt acttggacac caaacagata ggtcaagaca gcagcaattg atgagcctaa
    29341 catcatcgtt ggtaatactc ggatcgggtc tttcgcagca aacggaatag ctccttccgt
    29401 aatatgagtt gatcctaaaa taaaattaac caaacctgca ttacgatcat tagtatcaaa
    29461 atatttacca aacaataaag tagcaaaacc agtaatcaac ggtggtgcaa tgcaagctgc
    29521 tgacgcacca gccataaaag tcgtgtttcc ttgtgtcaaa agagctgttc ctgttacata
    29581 tgccgcctta ttaaccggtc ctcccatatc aaacgcacac atacagccaa caatcacgcc
    29641 aagaacaagt ggattcgaat attcaaatcc agctaaaaag ctcatcattc cttcatttat
    29701 agccttcatt ggacctgcca gcaaagacat cacgatgcca ataaatgcta caccaataac
    29761 tggatataag acgattgcct tcaagccatc tagttgttta ggtaaaatta tcagtagctt
    29821 ttgcaaaaat aagataaaat aacctgctaa gaacccagct aaaatacctc ctaaaaatcc
    29881 agtaccgcca ttcatggcta cgattccacc aacaaatcca acgactaacc ctggacgttt
    29941 cgcgatccct tctgcaatat aagctgctaa aactggaacc atcattccca ttgctgcatc
    30001 gtcaactgct tttaccattg ccgctgtagc attgtattgt gcatgatctg gatcagaaga
    30061 atagattccc caaacggcaa atgaaatagc aatcaatact ccgccagcta ccacgaaagg
    30121 caacatatga gagacaccgt tcatcaaatt tttatagatg ctacgaccaa aattagcacc
    30181 acttatcgct tctggttcta aagtatcagc agcttcatta tctgctaaga cagtaccttt
    30241 tcctgccaat gcttcgtcaa tcagccgttg tgcatccttg attcctgtac tgacagaaac
    30301 atcaatgact cgttttccca caaatctttc tgaatggaca tctttgtctg cggcaataat
    30361 gacagcatct gcctgtttga tttcttcagc cgttaattca ttctcgatcc caatttgtcc
    30421 atgggtctcc actttgatcg tgatgccttt tttcctagct gcttgctcta atgcctcttg
    30481 cgccatgtag gtgtgcgcaa ttcctgtcgg acaaccggtt gctgcaatta gttgatattt
    30541 tcccatcttt cgaacctctc ttccttgatt ttgatttgtt tacttaattc ctccacatcc
    30601 aaaaaatcag tcagtccttt acgaaaagca gtagagctgc ctgctgctat gcttttacgt
    30661 aacgtttcat caagcgatcg tcgattcatg tatcctgcta aaaaagtgcc taacatggca
    30721 tcacctgcac atgctgtatt gacaactttt ccttttggcg agtttcctcg aatcaccctg
    30781 tctttcgtaa aaagaatcgc tcctttctca ccgagggata acaaaacatt ttctgcgcct
    30841 gactctacta gtcgttgtcc ataaacaaag taatcttcat ctgtaaccat ttttcgtccg
    30901 aaccaagaag aaagttcttc ctcatttggt ttcagcaaaa acggtcgata gggtaaacaa
    30961 tccatgactt cttgatcact actatcaata atcaaacaaa tccgactgat ttctattaaa
    31021 acctttggag acagccctct tggtaaactc ccagaaacac aaagataatc ccctgcttgt
    31081 aatgctctta tttgatttaa aaaattatga acagctgtct gcggtatttc aggtccttga
    31141 ttcactaatt tgtattcttc tcccgtttga ttgacttgtg taaatacatt gatacgcgtc
    31201 ataccaggca cttcaataaa ctctgtttgg atttgtttct gctgtaaata gtcttctata
    31261 tactttcctg tgaacccagc agaaaaacct aatgccgtac ttgggaaatc tagcatcttt
    31321 aatactagtg acacattcac cccttttccg tttgcctgaa tgtcatcctc ttttgtgcgg
    31381 tttaccataa aaggatgcat ctcatctgtt tcaataaata gatcaattgc caaattcatc
    31441 gtgcatgtgt agatagacat aaccaacgac ctccttgatt ctattatgaa atacgcgaaa
    31501 tagaaaatgt tttcttaatc gtcccaacac aaagaaaacc tttacattta taaactcgtc
    31561 gtgctttttt taactaactt ttggtgaaag aaggaaagaa tatgaatcac aaattaagtg
    31621 aaacagagca gtacctctgg aactttatcg aacacctcat cctagagatc cctaactatt
    31681 ccatcgtgaa actaagtgaa caagcaaatg tctcaacagc caccattgtg cggacaatga
    31741 aaaagaaagg ctatgaaggg tttacttcgt ttaagcatca tctaaaagaa ggagaaaaca
    31801 agaacatcaa tttttcattt ttagataaag tagacaaagg aatccgccga gccattctaa
    31861 aaaatgaaca agaagtggta cgtacaatca atatgttgga aatcgggaac attgaagatg
    31921 caatacaaag aatcaaattt gctgaccggg tttttgtctt tgcccgagga ttttcagaaa
    31981 tgattggcca agaaatgctg gtaaaacttc aattaacggg aaaaaattgt cagatgcata
    32041 ctgatccaga aattatcaaa agcatcagtc ggaaactaac taagaaagac agcgttattt
    32101 ttgtttcttt gaacggtgag aaaacaaata aaaacatcaa aaataagatt tatgtcttta
    32161 tttttcaatt ttttaa
//
LOCUS       DACGDM010000023        30009 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.023, whole genome shotgun sequence.
ACCESSION   DACGDM010000023 DACGDM010000000
VERSION     DACGDM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.023"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(240..1967)
                     /locus_tag="IXR05_001171"
     CDS             complement(240..1967)
                     /locus_tag="IXR05_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4259708.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(1960..3153)
                     /locus_tag="IXR05_001172"
     CDS             complement(1960..3153)
                     /locus_tag="IXR05_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4259709.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3340..3984)
                     /locus_tag="IXR05_001173"
     CDS             complement(3340..3984)
                     /locus_tag="IXR05_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4259710.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4078..4212)
                     /locus_tag="IXR05_001174"
     CDS             complement(4078..4212)
                     /locus_tag="IXR05_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAQ4259711.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4214..6346)
                     /gene="feoB"
                     /locus_tag="IXR05_001175"
     CDS             complement(4214..6346)
                     /gene="feoB"
                     /locus_tag="IXR05_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAQ4259712.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6343..6816)
                     /locus_tag="IXR05_001176"
     CDS             complement(6343..6816)
                     /locus_tag="IXR05_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAQ4259713.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7217..7441
                     /gene="nrdH"
                     /locus_tag="IXR05_001177"
     CDS             7217..7441
                     /gene="nrdH"
                     /locus_tag="IXR05_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAQ4259714.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7600..9759
                     /gene="nrdE"
                     /locus_tag="IXR05_001178"
     CDS             7600..9759
                     /gene="nrdE"
                     /locus_tag="IXR05_001178"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAQ4259715.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            9809..10774
                     /gene="nrdF"
                     /locus_tag="IXR05_001179"
     CDS             9809..10774
                     /gene="nrdF"
                     /locus_tag="IXR05_001179"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAQ4259716.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(10863..12002)
                     /locus_tag="IXR05_001180"
     CDS             complement(10863..12002)
                     /locus_tag="IXR05_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4259717.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12311..13024)
                     /locus_tag="IXR05_001181"
     CDS             complement(12311..13024)
                     /locus_tag="IXR05_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAQ4259718.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13278..13979)
                     /gene="nagB"
                     /locus_tag="IXR05_001182"
     CDS             complement(13278..13979)
                     /gene="nagB"
                     /locus_tag="IXR05_001182"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAQ4259719.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14213..15745
                     /locus_tag="IXR05_001183"
     CDS             14213..15745
                     /locus_tag="IXR05_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4259720.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(15936..17138)
                     /locus_tag="IXR05_001184"
     CDS             complement(15936..17138)
                     /locus_tag="IXR05_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4259721.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17220..17909)
                     /locus_tag="IXR05_001185"
     CDS             complement(17220..17909)
                     /locus_tag="IXR05_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4259722.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18015..18383)
                     /gene="rplL"
                     /locus_tag="IXR05_001186"
     CDS             complement(18015..18383)
                     /gene="rplL"
                     /locus_tag="IXR05_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAQ4259723.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18436..18939)
                     /locus_tag="IXR05_001187"
     CDS             complement(18436..18939)
                     /locus_tag="IXR05_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAQ4259724.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(19349..20038)
                     /gene="rplA"
                     /locus_tag="IXR05_001188"
     CDS             complement(19349..20038)
                     /gene="rplA"
                     /locus_tag="IXR05_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAQ4259725.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20142..20564)
                     /gene="rplK"
                     /locus_tag="IXR05_001189"
     CDS             complement(20142..20564)
                     /gene="rplK"
                     /locus_tag="IXR05_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAQ4259726.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            20907..21575
                     /gene="sdaAB"
                     /locus_tag="IXR05_001190"
     CDS             20907..21575
                     /gene="sdaAB"
                     /locus_tag="IXR05_001190"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAQ4259727.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            21588..22460
                     /gene="sdaAA"
                     /locus_tag="IXR05_001191"
     CDS             21588..22460
                     /gene="sdaAA"
                     /locus_tag="IXR05_001191"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAQ4259728.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(22551..23570)
                     /locus_tag="IXR05_001192"
     CDS             complement(22551..23570)
                     /locus_tag="IXR05_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4259729.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(23743..24630)
                     /locus_tag="IXR05_001193"
     CDS             complement(23743..24630)
                     /locus_tag="IXR05_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4259730.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(24707..25252)
                     /gene="nusG"
                     /locus_tag="IXR05_001194"
     CDS             complement(24707..25252)
                     /gene="nusG"
                     /locus_tag="IXR05_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAQ4259731.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25353..25523)
                     /gene="secE"
                     /locus_tag="IXR05_001195"
     CDS             complement(25353..25523)
                     /gene="secE"
                     /locus_tag="IXR05_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAQ4259732.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(25547..25699)
                     /gene="rpmG"
                     /locus_tag="IXR05_001196"
     CDS             complement(25547..25699)
                     /gene="rpmG"
                     /locus_tag="IXR05_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4259733.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            25861..26505
                     /locus_tag="IXR05_001197"
     CDS             25861..26505
                     /locus_tag="IXR05_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4259734.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(26561..27064)
                     /locus_tag="IXR05_001198"
     CDS             complement(26561..27064)
                     /locus_tag="IXR05_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4259735.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27077..27123)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            27661..28626
                     /locus_tag="IXR05_001199"
     CDS             27661..28626
                     /locus_tag="IXR05_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4259736.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(28725..29897)
                     /locus_tag="IXR05_001200"
     CDS             complement(28725..29897)
                     /locus_tag="IXR05_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259737.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(29884..>30009)
                     /locus_tag="IXR05_001201"
     CDS             complement(29884..>30009)
                     /locus_tag="IXR05_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259738.1"
                     /translation="KLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
BASE COUNT         9138 a         6178 c         5357 g         9336 t
ORIGIN      
        1 tttgagaatg cacttcgtac ataataaact ttaatcacat tagtctttca tacctacgat
       61 cgatctcttt gactcgcacc cataaattca taatagtttg tcggcgtctt tggacgtttc
      121 gaagatgagc tacgcattct ctttttttat agacaaaaaa gatagagacg aacatggagc
      181 ttccaaattt ggatatttga tccaattttg gaagctccat ttatttcgtg tctgtctttt
      241 tattttttcc agctttcgac taattcttgg ttctctttga tccagtcttt tgctgcttgc
      301 tgtggatctt ttccattgtt gatttccaac ataacttttt ccatatcttt ttctgaccaa
      361 tggaaattgt ctaatacttt gtaagcttct ggctggtctt ctttcaatcc ttttcgaacc
      421 atcgtatgga tctgctcttc gcttcccatt ccgttttcag gatcttctaa gtatttcaga
      481 tcatatttgg caaacatcca atgaggtgtc catcctgtaa ctacaattgg ttcgtgtttt
      541 ttgatcgctt gacctagtgc aacggtcatt gctcctgaag aagatgtctc tactttccag
      601 tctttcaagt tgtcatattt ttggatcgtg ttttcagcag ccgtaactac accagctcct
      661 ggctcgattc ctatgatttt cttacctgcc tgatcggtta actcatcgat cgaatttaca
      721 tccatgtagg ctggcactgc taaaccaact tttgctcctg tcaaattggc acctaggtct
      781 tcgacttgat ctttatattg tgcatattgt gaaccatgag ttttaggtag ccaagctgaa
      841 accatggcat ctgactcgcc atttgaaaca gatttccaca tgattgaatt atctaatggc
      901 gtcatcgtta catcatagcc catttgtttc aatacttcac cgactacatt tgttgaagca
      961 acttctgtat cccattcaac ataagataag ttgatacgtt ttgtttcttt ggcagatgaa
     1021 aaactcccta taccaatcgc acctaagatc actactacta cagcaccaat gatcagtcct
     1081 tgacgttttt tacttttctg tgttgttgct cctgcagctt ttttattgtt tggctggttc
     1141 aaatgctgtg taaaacggtc aatgatgatt gctaagataa ctaatgcaac cccgttgaca
     1201 aatccattcc cgacttgtgc tctttgcaat gctgataata cgccgcgtcc taagccgggt
     1261 gcaccgatca tagaggcaat aacgaccatt gaaagtgaca gcattgttgt ttgattgatc
     1321 cctgccatga tcgtactttt agctaaaggc aattctagtt tgaatagttt ttgacgactt
     1381 gtgctcccga atgaatcaga agcttctact aattctttag gaacttgtcg aatccctaaa
     1441 ttcgtaaaac gaacggttgg tggcagagca aagatgactg aggcaaatac ccctggaacc
     1501 atcccgatac cgaaaaatgc aactgctgga atcaaataaa cgaatcctgg cattgtctgc
     1561 ataaagtcaa ggatcggttt gataatactt tgggctttac tgctttttgc catcaagatc
     1621 cctaatggta ccccaatgat gatcgagatc acactagata aaagaacaag tgtgacagta
     1681 ttcatcaaat cattccatag accttggtta taaataaacc atagaccgat taatgtgaac
     1741 aacgtaagtc ctggacgttt cttagaaata aagaaagctg ctaccgtcaa taacaagata
     1801 aacaaaggag ctggaatcac taacagtaaa tttgtaatcc ccgacatcac tgcctgtcca
     1861 atcgtttgta aaaatgaaaa taggccagaa aaagttgtcg taaaccattc tgtgatattt
     1921 tctacccagt ttgccactgg taattgatag ttcaatagat tattcatgtt cactcacctc
     1981 gcttgtttct gctaatgctt caatcacact acctcggatg acgacacctt ttaattttcc
     2041 atcctctaca actgcaagtg gagtcggtga gtcataaata atattgaaaa tatcacttac
     2101 caccatgtct ttcccaatca ccgtcacatt ttcatctagg aagtcgatca atggacgttt
     2161 ttgcttccta gcttctaacg cttgatctgc agtgatgatc cctttcaggt gtctctttct
     2221 gtcaacagcc atcagcatgc tgacttcttc attacgcatc cttgtcaatg caacgtttgg
     2281 tccatcagat tcgatattcg tcgtcaatgc aggtaccatg atgttttgag ccgtaagcac
     2341 tttggaacga tcgacttctt ccacaaattc acgtacataa tcatttgctg gattggtcaa
     2401 tatttcttca cctgttccga tctgcatgat ttcgccgtct ttcatcaagg cgattctgtc
     2461 cccaatccgt aaagcttcat tcaaatcatg ggtaatgaaa ataatcgttt tttgaacatt
     2521 ggcttgcagg tccagtaatt cgtcttgcat ttctcgccgg atcagcggat caagagccga
     2581 gaacgcttcg tccatcagca agatctcagg atcatttgct aaagctctgg ctaggccaac
     2641 ccgttgttgc atcccaccag ataactgact aggatattgg tctttaaatg aaagcaaact
     2701 agaattttct aatgcttttt ctgctttttc ttgtcgttct tctttaggta caccacggac
     2761 ttctaacccg tattctgtat tttccaagat cgttcgatgt ggaaacagac cgaagttttg
     2821 gaaaaccata ttgattttat gacgacggac ttctcgcaat tcttctttgc ttaacttcga
     2881 tacatcttct ccatcaatat agatactgcc cgaagttggc tcaatcagac gattcaatag
     2941 acggatcaat gtggatttcc cactcccgga aagccccatg atcacgaaga tttctccttc
     3001 ttttacgtca aaattcacgt catacacacc aaccgttgca ccggttttct ttaaaatctc
     3061 cgttttcggc tggtgatcat tcatcatatc taaagcggct tgtgtctttt taccaaatat
     3121 ctttgttaaa tgttttactt ctacttttac caaacaaatt ctcctttttt atgtaaattc
     3181 atttttcttt ctgaaaaaag tgaccacact atgttaacat catgtagtca ctttgtcaaa
     3241 aatgaaagaa atttgcttgt ccaaactgaa aaaaacttgg ctaaatcttt gtaaataaaa
     3301 ggtttagcca agttaatatt tttttaatat ttcacacaat cattctgcaa gctgatgctc
     3361 cgggtaaaaa aagtttgtca tacgctgtag tgtatattca tttccaataa aatgaacgat
     3421 gtcccctgcc gtaaatttag cataggggcc aggtgaaaca agcagttctt cattatgaga
     3481 aattgcgata actgtggcgc cagtcgcctg ccagatattc aactcgctaa ttgaacggtc
     3541 cagatgcatt gctttttctg ataaagataa ttcaaacgga agtaaaggat tcatcttatg
     3601 tattcgcttc gtttgattga ccagctgatc caataattga gaaaaatgat tcagctcatc
     3661 ttgttgcttc tccacacttg ccatgatttc tgcttttgta tcttggatgg attgtacatc
     3721 ttgatattgc aataggaaat cttttgcttt ttccttcgaa gcaacaaatg ccccacttcc
     3781 atgccgtact tccatgattc caagatctac cagcacattg atagccttgc gggtagtctc
     3841 aggagaagca ttgtacgtac tggcaagtgt tgagcgggca tggatcttct cacccacttt
     3901 atatcggttt tcaacgatac gttcggctaa atcaacagca atctgctggt agcgcgggcg
     3961 gacgattttt ttctttccag acattttctt tcctctttct ttttttactt tccctcatct
     4021 tactatgctc tagcaaaata agcaaaaaag gggagaatag cctcttgcaa cgactgatca
     4081 tcgcttgatc tgttcctttt ttactgggca agctgtttga cagtcatcac aattcttacc
     4141 ggattttaaa cgagtataga caattgcgcc tgcacttcca aagattaaca cacttaataa
     4201 gaatgtcgcc atcctattcc tctccttcta atgacaatat agtataaaac tggttcttgg
     4261 attttggctg acggaacaaa acataaacga gtcctatcat cagtaaaata gcaagatacg
     4321 tccctaacgc tacctgtcca ccctccaata agtgtcccaa ctgataaatc acaaaactaa
     4381 ctaaataagc taaaccgcat tgatagccta tggcgatcca agtccatttc ttggcattca
     4441 tttcccgatg gatagcccca attgccgcaa aacaaggcgc acaaagtaaa ttgaaggcta
     4501 acaatgaata agctgctgcg ggagtatatg tgtgttgtag cacttgccag atttctctgc
     4561 cattttcgga tacttccgca tgaccaaaca aaataccaaa tgtgccaata atattttctt
     4621 tagcgaccaa tcctgtaatc gctgcgactg ttccttgcca gtttccccaa ccaagcggct
     4681 gaaaaacaac tgccaggatt cgcccgaaaa aggctaagat actttggtct tcagaaacag
     4741 gttgagcata aaaattataa gaagagctga accagatcac gatactagaa acaaagataa
     4801 tcgttcctgc ttttttaaca aaagacttgc tgcggtcata ggtttgtctt aggaccgctg
     4861 accattgagg aaaatgatat gcgggcaatt ccatgataaa aggagctgta tctccagcaa
     4921 acaaacgtgt ttttttcaag ctgattccag agaaaataat tgcagtcata ccaagaaaat
     4981 aggcagaagg agctacccaa gattgatgag gaaaaaaggc ccctgctact aaggcaataa
     5041 tcggcaactt tgcagaacaa ggcatgaagg ttgtgaccat gatcgtcaaa cgacgatctt
     5101 gctcgttttc aatcgtgcga ctggccatga cgcctggcac tccacatcct gtagcaatca
     5161 gcataggaat gaaggatttt cctgaaagac cgaatttcct gaaaagtcga tccatgacaa
     5221 aagcgatcct cgccatatat ccgcagtctt ccagaaagct caagcataaa aacaatataa
     5281 tcaattgcgg tagaaatcct aacactgctc ccacgcctgc gatgatgccg ttcaagatca
     5341 gctcctgcat ccatcccgct acttgccatt cagctaacaa tctgccaaca tgttctggta
     5401 accatgtacc aaacaatgtg tcattgatcc aatctgtccc cattgttcct actgtttgaa
     5461 tagccagata atagatcagc cacatcacaa atgcgaagat cggcaaggct aaccaacgat
     5521 tcgttgcaat ctgatcgatt ttgtcactca tcgataattg gaaagaatca tttgacacaa
     5581 cacagagtgt acatagttgg gtaataaatt cataacgttc attgaccaga atcgtctcac
     5641 tatcgtcgtc caatagtttc tctgttaact ggatcagttg ctcgatctct ttttgctgag
     5701 aaactgctat ctcgtaatcc tctcttacct tctgatctcg ttcaaaatat ttcattgcat
     5761 accagcgttt cttgccgctt tgttctccta gtacatcttc aatttcatgt aaagctgctt
     5821 ctaaacgtgg atcatatgta cagggaacag gaatagaagg ccgctttttt gcagactcct
     5881 gaatcttttc gattagtttt tcgattcctt gctttttcaa tacgctgatt ggtaaaactg
     5941 gtacaccaag accataggaa agcttttcta gattgatttt ttttccttct tttttgatga
     6001 catccatcat attcagacca atgatcatag gaatgtctaa atccaataac tgcgtagtta
     6061 aataaagatt tcgttctaaa ttggtagcat caataatgtt gatgatcagt tcaggctgtt
     6121 cctgaaccaa ataatctctt gcaatcactt cttctggtgt ataaggagac aaagaataga
     6181 tgccgggtag gtcctgaata tgaatgttcg gatttttttt caacgatcct tctttttttt
     6241 ctactgttac gcccggccaa ttccctacat attgattcga accagtcaag agattgaaca
     6301 agctagtttt cccgctgttt ggatttccga ctaacgcgat attcattctt tttcctccct
     6361 ttgtatcaag attagttcgg cctctgactt tcgtaacgtc agttcatacc ctcgcactgt
     6421 cagttcgatt ggatctccca gaggggctag ttttcggata actattttta catttcgcgt
     6481 caatcccata tccattaacc gtcgcttcac tgcgccttgt ccgtggattg ctacgacgat
     6541 cccagtctct cctgctttta attgatcaag agaagtccag ctttcagagg aagcagtctt
     6601 tttattgaca aagatttgac ctagtatttc ccgacttact gccactcgat gactttttac
     6661 cagtaaaatg gcattgttgc ctgataaatt gacgacgacg attttacttc cggcaacgat
     6721 cccgatattt tgcaaatggc gttttgtttt ttcttctgtt tcgattcgtt cgacttgata
     6781 aacgaaattc tgctttgcct gcgctaaggt ctgcatattg attcctctct tgtgaaataa
     6841 atcatgtatt aaaatcattc attatatgtt ctaattttct tacgtgttac gcaaataaat
     6901 gagaatcatt ctcacataga atactctcgg taattgagaa tgtcaattat acttgtgata
     6961 ttatgagcga atctttagta ttgatagata aaaatgagaa aaaaatattt cttcatagtt
     7021 ttccacaatt ttttctctat taaatttgct attttcccac acgatacttg ttttcagctc
     7081 ttttttcaaa aacacaaaac ttagtattcc acagtttcca caacacaata tgtagtgttt
     7141 gttgtttgac ttttttacta agagttttat actatctatt atagataata agaatgtgtt
     7201 agaggaggca ctcaccatga acgtaaaaat cttttctaaa aataattgta tgcaatgtaa
     7261 gatggtcaaa cggtttttaa cagaaaatca aattgctttt gaagaagtca atatcgatga
     7321 acagcctgaa gcagtagact ggttgaaagc acaaggattc caaagtgttc ctgtcattac
     7381 ttctgatgca gaaacagtta tcggattccg tcctgatcag ttgcgtaaac ttgccagcta
     7441 acatgactaa aagaatcaaa acgtgataca tggatttgaa gggcttgaga cagcaccagt
     7501 ttttgtcgca aacttccaaa tcctttttta aagcttaaaa acaatgcaat gatttgcaat
     7561 caagcatcat caaatacgaa atgaaggttg ggcgtacgta tgagtcttaa aaatttacaa
     7621 gatgtcagtt atttcaagct gaataatgaa atcaatcggc cagtcaatgg tcaaatccct
     7681 ttgaataagg ataaagaagc tttagttgcc ttttttgagg aaaatgtcaa accaaatacg
     7741 atgacttttc tatctattat ggaaaaaatc aattacttga tcgatcaaga atatatagaa
     7801 gcagaattca ttcaattgta ttcaccatca tttattgaaa agctatatca atttttggac
     7861 gagcaacatt tttctttcaa atcttttatg gctgcttaca aattttattc tcaatatgcg
     7921 ttgaaaacca acgacggttc cgcttatctg gaaacttatg aagatcgagt agccttcaat
     7981 gcgctttact ttgcgaacgg ggatgaagaa ttagcacttg ctcttgcaga cgaaatgatc
     8041 catcaacgat atcagccagc tacaccttct ttcttgaatg ctggacgtaa acgtcggggc
     8101 gaattggtgt cttgtttctt gactcaagtc actgacgata tgaactctat cgggcgctca
     8161 atcaactctg ctttgcaatt gtcccgtatt ggtggcggcg tagggattac tttatcaaat
     8221 cttcgtgaag ccggcgctcc tatcaaagga tatgagggtg ctgcaagtgg tgtcgttcca
     8281 gtcatgaaat tattcgaaga tagtttcagc tattctaatc aattaggtca gcgtcaagga
     8341 gctggcgtgg tttatttgaa cgttttccat ccagacatta ttgctttcct ttcagcaaaa
     8401 aaagaaaatg cagatgaaaa gattcgcgta aaaactcttt ctcttggcgt gatcgtacct
     8461 gataaatttt atgaattgac acgtaaaaac gaagatatgt atttatttag tccatatagt
     8521 gtcgaaaaag aatatggtgt cccattctct tatgtaaata ttacagctga gtatgatcat
     8581 ctagttgcaa atccaaacat tcgcaaacaa aaaatcaaag cgcgtgatct tgaaaatgaa
     8641 atctcaaaat tacaacaaga atctggctat ccttacgtaa tcaatattga tacagcgaac
     8701 cgcgagaatc caatcgatgg caagatcatc atgagtaatt tatgttcaga gattttacaa
     8761 gttcaaacgc cttctgtgat taacggcaaa caggaatatg aagtattagg aacggatatc
     8821 tcatgtaact taggctcgac aaatatcgtg aatttgatgc aaagccctaa ctttggtcaa
     8881 tctgtgcgta cgatgactcg tgcattgaca tttattacag atgcatctga tatcgatgtc
     8941 gtaccaccga tccaaaacgg aaataagctg aatcatacga ttggattagg tgccatgggc
     9001 ttacacactt atcttgcaaa agaacaaatg gaatatggct cagaggattc attagacttt
     9061 acaaatattt acttcatgct gttgaattat tggacacttg ttgaaagcaa caatatcgct
     9121 cgtgaaagaa aacaagtttt ccataatttt gaaaaatcag cttatgctga cggcacttat
     9181 ttcgaaaaat acgtaactgg agaattccag ccaaaatcag aaaaagtcaa agcattgttt
     9241 gaaggcattt ttatcccaac tgctgaagat tggaatgctt tgaaacaagc agtaatgaaa
     9301 gatggactgt atcatcaaaa tcgcttggca gtagcaccaa atggctcaat ttcatatatc
     9361 aacgatacga gtgcaagtat tcatcctatc actcgcatga tcgaagaacg ccaagagaag
     9421 aaaatcggta aaatttatta cccagcgcct tatctatcca atgagacgat tccgtattac
     9481 acttctgctt atgatatgga catgcgtaaa gtaatcgatg tttatgcaat ggcacaacaa
     9541 cacgtcgatc aaggcatgag tttgacttta ttcatgcgtt ctgaaatccc agaaggcatt
     9601 tatgaatgga agacaacaac gaagcaaacg acacgtgatt tgaatatttt aagacattac
     9661 gctttccaca aaggaatcaa atccatttat tacgtacgta cctttactga tgatgcagaa
     9721 gaaatcggaa gcaatcaatg tgaaagctgc gtgatctaat atcatagata gattcgctta
     9781 ttcatatttt aattaaagga gcattctcat gtcagaaaca tattatgaag caataaactg
     9841 gaatgaaatt gaagatatca ttgataaatc cacttgggag aagctgacag agcaattttg
     9901 gctagataca cgtatcccac tttcaaatga cctagatgat tggcgtacat tgtctcaatt
     9961 ggaaaaagat acagtaggac atgtatttgg cggtttgaca ctgctagata ctgtccaatc
    10021 tgaaagtggc atggatcagt tgcgtaaaga tgtccgcact ccccatgaag aagccgtttt
    10081 gaacaatatt caattcatgg aatccgttca tgccaaaagt tattcttcta tttttagtac
    10141 actgaatacg aaaaaagaaa tcgaagaaat ttttgactgg acaaatacga atccttatct
    10201 gcaaaaaaaa gctgagcgta tcaatgaaat ctacaaacac ggtacaccgc tagaaaagaa
    10261 aattgccagc gtctttttag aaacattctt gttctattca ggtttttata ctcctcttta
    10321 ttatttagga aacaacaaat tggctaacgt agcagagatc atcaaactaa tcatccgaga
    10381 tgaatctgta catggaacct acatcggtta caaattccaa ttaggattca acgagttacc
    10441 tgaagcagaa caagaaacgt taaaagactg gatgtacaat cttctttatg agctttacga
    10501 aaacgaagaa cgttatacag aagaattata cgatccaatc ggctggacag aagaagtcaa
    10561 gacattccta cgctataatg ccaacaaagc attgatgaac ctagggatgg atccactctt
    10621 tccagatact gccaatgatg tcaacccaat cgtaatgaac gggatttcaa caggcacaag
    10681 caaccatgac ttcttctcac aagtcggaaa cggctatttg ttaggtcatg tagaagcgat
    10741 gaaagacgac gattatttga ttggattgga ataaggattt attttaattc aaaaattttt
    10801 cgaaaaataa aaagagttta gcgtacagat attttaaatg tacactgaac tcttttttat
    10861 gcttattcac ttgtttcttc cagcactttt ggactgtcta acttttccga aacatgttcc
    10921 attcttctca ataaatagat tttccggata tttaatatta tcgtcttaat cactgcatag
    10981 acaggtatgc aaatcagcat gcctaatatt cctgcgacac ttcctgctcc aatcaatacc
    11041 aagatgatcg tcaaaggatg gatattcatt gatttcccaa ataacaacgg cttgatcaaa
    11101 tttccatcta attgttggat cactaaaatc gacaacgcca tatacaaagc ttgaaatgga
    11161 gagataaaca aaccgacaat gattgctggt accgctccaa taaaagggcc gacatacggg
    11221 ataatattcg tgattccgca aatgaccgca agcaacaagc tataaggctg atcgaatatt
    11281 ctcattgcca aaaagctcat tacaccaata atcaaagcat ctaagatcgt actgctgata
    11341 taggcagata atgtttcgtt taattctttt accgtttggc gtaactcttt acgaatcgct
    11401 ttcggaaaga agtgagacaa cgcatcaata aatttgtgcc catccttgaa cataaatagc
    11461 aaaataaatg gaacggtaaa taacaaaata aaaaattgca tcataaatga aatgattttt
    11521 gagacacttg cagataaact gactaatatg atattgaaca aattactaag agataaattt
    11581 gctgatgcta attgttcttc caaattgaaa tttttaaact cttcccgctg cgccaattca
    11641 tttaaccatt tgcttgtttc atctgcatac attggcaagc tctgggtcaa ttgaattgtc
    11701 tgttccatta actgaggcac tacattcatg acagttaaaa caactaaaat gattacgacc
    11761 aaaaacgtca ataaaaaacc gaacactctc gggatccgat gcttttcgag aaaaacaacg
    11821 attggatcga acatataata gataaaacca gcaacaagca atggtaaaaa aactgccgaa
    11881 agcattttca atattggact aaaaatattc ggcatttgta aaataaagta cacgccgatg
    11941 atcgtgagta ctagctccac tgtccagaaa aataattttg attgtttaaa acgtgattgc
    12001 atacatctcc tccaaggtcc tttgatactt ctattctatc atttaacaaa gagttacgcg
    12061 ctgagatttt catttgctta aaaaaaacaa aaaaaataaa catattttaa tgagtagacg
    12121 agtacttaaa caaaaacacg gtttggagta gtgacaaaaa ttatactgca gtcccttttt
    12181 ccaaataaac ggtgttcaaa agcttgcatc ttcgtaataa gcccagccaa acgaaaaata
    12241 taaggaacta tttttatttg gctgggctta ttacttgatg taggacatct attttacaac
    12301 ctcagatcat ttattgcgca atactgacta aatgcaactt tgtgatattt ttgtgtacgg
    12361 acaactcctc gatcacatcg gcataagtga gcccttttgg aagatcaatc gtatagatat
    12421 ttttgtacac tcggtagtca tcaacgaatt ttacgtcaaa attcacatct tcgattacga
    12481 tatttttctc ttcaaaataa tcggtaagaa aatctttggt ttcttttcta tggataaatt
    12541 ggatttctaa ctttttagtc gtaggtacat ggatcacgcg tttcactact gtgagtgcaa
    12601 tagcaatccc gataaaactg atgatcgcaa tggaatagta acccatgccg atggcgatcc
    12661 ctaatccagc aattgcccat aaagaagcgg cagtcgtaag tcccgtcacc gattgtttcg
    12721 tgacgatgat cgttcccgcg cctaagaaac cgacaccact caccacttga gcaatcagcc
    12781 ttgcttcatc tgaacgaatc gttccagcaa gctgtggata ctctaaagca tctcttaatg
    12841 caccactagc gatctcaact tggatcaatg caatgataca tgctcccata caaactaaaa
    12901 tatgcgtacg catacctgct ggacgatttt tatattgtcg ttcaaaaccg attgctccgc
    12961 caaatagcat agcgatccct aaacgtaaaa taatctctgg aattgtcaat accatatcat
    13021 tcatctaaac accctccagt ccaatatatc atgtctgaaa ggagcagaca aaaaaagtgc
    13081 aatttttacc tcttacgaaa aaaggactgt gacaaaattt ttgtcatagt cctttttatg
    13141 aataaacggt gttcaatcag ctgaccctcg gtattactca acaaacggca aaatatgggg
    13201 agctattttt cctttgtctt ctctaatact caggtcaaaa cgctgatttc acaacctctt
    13261 tagcctacta ttgaaaatta caacttactt gctgcttctt catcgatgat cacaacaaca
    13321 ttgtcgtgat tttgcaatac acttgctggc aaatgattcg ttacaggtcc ttcaatcatc
    13381 cctttgattg catcagcttt gctttcgcca aatgccatca agacgatttc tttacttttc
    13441 ataattgaac cgattcccat tgaaacagct tttgttggta catcttctgc tttatcgaag
    13501 aatcgtttgt ttgcattgat tgttgattct gttaagtcaa ctactgaagt cgttccgtca
    13561 aatgaagcac caggttcatt gaaaccgata tgtccatttt gcccgattcc taagatttgg
    13621 atatcgattg gatgtgcatc gatgatttga tcatactttt tgcatgctgc ttccagatct
    13681 tctgcttttc catctggtac aaacgtttct ttgaatggtt ttttatcaaa taattggaca
    13741 tccatgaaat gacggtagct ttgttcatct gaaccgccta gtccaacgta ctcatctaag
    13801 tttacagaag tcatttcact gaaatccaaa tcgcttgaag tcatttcttt atataaagta
    13861 actggtgtgc ttcctgttgc caatcctaat acttttgcac ctttgttcat accttctttg
    13921 atgatttcaa atgctttttt tccgccttct tcagcgtttt ttacacgaat gatttccata
    13981 gtgattgctc ctttatattt tggtatagcc caattatagc attctttttt tctttttaca
    14041 ataattagta tagaccaaat tgcatttttt tcattttctt gacaataaat aggaatccgt
    14101 gttaggtttc ataagatggt tcaatcaaac aatccatgtt gcatgaaaac caagcaagtg
    14161 attcactgtg gacgctttat gtctgcagtt tttttatgaa aaaggagtta ttatgagtat
    14221 actgacatta aacaacatta cccagcaatt tggcgacaaa atcctctatg aaggtgtcga
    14281 tctgcaatta aatgctggcg aacatcttgg gctgattgga caaaacggag ccggtaaaag
    14341 tacattgatt aaaatcatca ctggtgagat cttaccagat gacggacaga tccattggca
    14401 aaaaaatatt cacaaaggtt acctcgatca atatgtggaa gtcgatgaaa cattaacaat
    14461 cgaagaattt ctaaaaactg cgtacgcaaa agaatacgaa aaggaagaaa aaattgcttt
    14521 tctttaccaa acatatagcg agaccttcga tgattccttg ctggaaaaag ctgggaaact
    14581 ccaaacggaa ttagaccaag gagtgtttta tcaaatcgac accttagttg ctgagatgag
    14641 cagcgggttg gggatcgatg tcttaggttt agattcactg ttgaaaaatc taagtggtgg
    14701 acaacgttca aaggtgattt tagcaaaact acttttagaa aacccagatg ttctgatctt
    14761 agatgaacca accaatcact tagatgatca gcatatccaa tggctgacgc agtttcttca
    14821 ggattttgac ggtgcgtata tcgtgatttc ccatgaccaa gaatttcttg atcagatcac
    14881 cacccatatc gcagacatcg agtttggaaa gattactaag tatactggcc atctaaaaca
    14941 agcattgaaa caaaaggaac aaaatcgcga aagctatttg cgccaatatc atgctcaaca
    15001 aaaacaaatc gaaaagaccg aagcttatat tcgaaaatac aaagccggtt cccgatcaac
    15061 gatggcaaaa agccgacaaa aacaattaga taaaatcgaa cggctgacgc ctccagcttc
    15121 agcaagtaaa gctgtctttg attttccatt ctcgcctatt gtcacgacat tagcagtgga
    15181 aacaactgat ttagtcatcg gatatgatcg accgctactt gcacccatca atttgaccat
    15241 ccgctttggt gaaaatattg ccattcgagg cttcaacggg attggaaaat ctactttatt
    15301 aaaaacactg atcggtgaga ttgaaaaaat aagtggcgat ttccacttcc cagataacac
    15361 aaaaatcaat tacttttcac aagatctgta ctgggaaaat ccattagaaa caccactaca
    15421 atatttaagc agtcaatttc caaaagcgac tatcaaagaa ttacgtcgcc aactagctaa
    15481 agcagggtta gttaatcaat tagcaagtga acctctcact acattaagtg gtggggaaca
    15541 aactaaggtg aaacttgcac agttgacaat gaaccaaggt aatttactga ttctcgatga
    15601 accgacgaac catatcgatc aagaaacgaa agaaagctta caagacggga tacagaaatt
    15661 tccaggaaca gtaatcatcg tctctcatga acaagaattt tatcaagatc ttgtgcaacg
    15721 agtcattgag attgaaccaa aataaacgtt tgattgaata gttgaaaaaa aggagctgtg
    15781 acaaaagttt tgtcacaact ccttcttctg aataaatggt ggccaattag ctgaccttcg
    15841 gtattagctc aaaaaacggc aaaatatgag gagctatttt tatttggcta ttcttattac
    15901 ttgatgcaga acagcttttc acaacctctt ttcgtctatt ttttattttc gagatttctc
    15961 tttcctttaa aaacaactgt ttgaaagaag aacgcacatc cttgaaaaac aagcccgcta
    16021 accgttacac ctaaccagcc atactgctgc cacattgtcg tccctagcaa tgaaccagcc
    16081 gcacctccaa taaagtacat aaacataaat acagtattat ttcggttgct tgctgcttca
    16141 cctagccctt gtactcgtgt ttgattggcg acttgaccaa attgattccc gacgtctaat
    16201 aaaataatag ctaaaagcaa aatggccaaa tggcttccgc caaccaataa agcaataaag
    16261 cttattgttt gcataacaag tcccatatac acgatttttc tttcagaata agaatctgcc
    16321 agtcgtccca cgataggtgc agcaactgct ccagacaaac caaaaatcgc taatatccct
    16381 gcttcgaatg ttccccaatt gtaggcggga ctgctgatat aaaaaatcaa cgtagaccaa
    16441 aagatcgaaa atgttccaaa catgaaaaat ccactgactg ccgcttctct taatagacgt
    16501 tgagaagcaa ctaaatgcgg caaactttta agtgaatcaa ggtatgaaac agctgtacta
    16561 ctttgctgga cagaacgcgg cattttccag taaagcagaa gtgtaagaat tccgactgca
    16621 cataaagcaa ataaatagat catccgccaa gaaaaaagac tggcaacaat accagatacc
    16681 gtccgagaaa gcaaaatccc cacgagtaaa ccgctaagca atgtacccat gaccttccct
    16741 cttgcttttg gtcccgctag taccgcaccg taaggaatga tgatttgcgg cacgatcgaa
    16801 agtaatccta ttaaaaaaga agcgcatgca aataacgtaa acgaaggcgc aaaaaaagcg
    16861 gccaacagag agacggcaga taacgctgcc attcgaatga tcaattttgg acgatccacc
    16921 acgtccccta aaggaactaa aaacagtaac cctaacgcat agcctaattg ggtcaacatc
    16981 gtcaatatcc cgactgcact tgtgctaaca gataaactag ctgctacttt tgttccaatc
    17041 ggctggatgt aatacatatt ggcaacaaca acgccacaag tgattgataa tagtaaaata
    17101 agcgaagttg ttaaaggttt tttttcatta ctcttcattg atttccccca tttcctatct
    17161 tagtttacaa cttatggaaa agattggaaa tagaaaaata caactattcg ccacacttat
    17221 tatttgtgct tttgttttcc ttgttttttc ttgcgatctt tataaatgaa gacaactaac
    17281 cctactagca cagtaacact tgcaaccaac gtgactgcag ttttgttata tccgtgaaac
    17341 agagcttctc caccacacgc atacaacaca gacgaaggga tgactccaat cacgatcgac
    17401 aatatgattt gctgtagagg caatttcatc gcatctgcag caaaattgac catagaagat
    17461 ggaataaccg gtatcatata gcctaacatt acacctattt ttggatgttt catttgtcgg
    17521 attgcttgca cccaatgatt cgtttcggtt ttcttatcta aaaattttaa gcgatgcata
    17581 aggaaaattg cagtgatgtt accaagagca ttacccaaaa tgttgatgat cgcacctgtc
    17641 agtggtccaa agctcaaacc agcaatgact ccaactactg aagtaggaat acctggaaca
    17701 gcacacatca ccgctgtcaa tacgatcaag agtatcgatg caaaagtccc atgcgaacga
    17761 atatgtgcga gtagctctgc cttactcgct ctcggattta aaaataattg gatgtctgtc
    17821 tgatattcta aatacaaccg atagcccact accagtatca gaatgattcc caacgagatc
    17881 aatatcaatc ggattatttt ctttttcata tttcctcctg aaaaaaatct atattcatta
    17941 aataatagtt taacataaaa acaaaaaagc accgaaatcc aacataggat ctcagtgctt
    18001 ttaaatagta aaaattattt aacagttaca gatgcgccaa cttcttcaag tttagctttc
    18061 aattcttcag cttcttcttt agatacgcct tctttaactg gtgcaggagc gccatcaact
    18121 acagctttag cttctttcaa gcctaaacca gttgcttcac gaactgcttt gataacttta
    18181 actttttggt ctccagctgc agttaattct acagtgaatt ctgtttgttc ttcagcagca
    18241 gcagcgccac cagcagcagc tacagctaca ggagcagcag cagatacgcc aaattcttct
    18301 tcaatagctt taactaggtc gttaagttct aggatagttg cttcttttaa ctcagcaacg
    18361 atgttttcaa tgttcaatgc cattataatt tcctccgttt aattgttctt ttttatttaa
    18421 tgctttatgc ggcaattaag ctgcatctcc atcttctttg tctgccactg ctttgacagc
    18481 gtaagccacg ttgcggactg gcgcttgtag tacagatagc aacatagata gaagtccttc
    18541 gcgatttggc aattttgcca atgctgtgat ttcttccaat gaagagactt taccttcgat
    18601 gataccgcct ttgatttcta atgcttttgc ttctttagca aattcgtcca tgattttcgc
    18661 tggtgcgact acatcttcgt tactgaatgc aacagctgta ggtccagtga atacttcgtc
    18721 catgccttca aggccagctt ttttagctgc acgtgaaaga atagaatttt tgataacttt
    18781 catttctacg ttagcatcac gaagttgttt acgtaaacgt gttacttcat caactgttaa
    18841 tccgcggtag tcaacgacta ctactgatgc agctgctgta aatttttcgc ttacttcatc
    18901 aacgattgct gctttttttg cgataattgc ttcactcatt tttgagtttc acctcctgaa
    18961 ttttgatgga agagtttttt gcactgaaaa ggcaagtcac ttttatagtt actttgctca
    19021 accagtatta ttcatcacct attcacttcg ttcatagtga ttctactcgc tttgctcgaa
    19081 aggaaactcc tttcgctttg ctcaaccagt attgttcatc atctcttcac ttcgttcata
    19141 gtgattcaca ataaaaaact ctatgccacc gcagacatag agggactatt gaatatattc
    19201 aataaacgtc ctcggtagga aattaaggct tgatgccacc tactgtcttc ggtacaagtt
    19261 aattattaac ctcaactagc ttagcatgct aaactagttg agtcaagaat tatttttcag
    19321 ttggatcaat caacattcta atatttaatt agaaagaagc ttggtcaaca tggataccag
    19381 gtccaaatgt tgttgtgatc gttacatttt tcatgtattg acctttagct gctgatggtt
    19441 tagcttttag caatacatca tggattgctg caaagttttc aactaatttt tcatcgtcaa
    19501 atgaaacttt tccgattggt acatggatat ttccagcttt gtccacacgg taagttactt
    19561 taccagcttt cacttcgttt actgcttttg ttacgtccat tgtaactgta ccagttttag
    19621 ggtttggcat taagcctttt ggtcctaata ctcgtcctag acgacctaca gtagccatca
    19681 tatcaggtgt tgcaacaact acatcaaagt caaaccatcc gttttggatt ttttgaacca
    19741 tgtcgtcgtc acctacgaaa tctgcaccag ctgcttcagc ttcttttgct ttgtctcctt
    19801 tagcaaaaac taaaacagtt tgtgttttac cagttccgtt tggtaataca acagcaccac
    19861 ggatttgttg gtctgctttt ttagggtcta cgttcaaacg gtatgcaact tcaactgttg
    19921 catcaaattt tgcaatgttt gtttcttttg ctaaagctac tgcttcggca acaggataaa
    19981 ctttacttga atcaactttt tttaatgcat cttgcatttt tttgctcttt ttagccattt
    20041 tggttcctcc ttgattgtgg ttataacggt tgtacctccc acgtgttcta tatctttcaa
    20101 tatagagcca actgagaagc tgctgtctta gggtgtatag attattctac agtgatcccc
    20161 atgcttcgtg cagttccttc aaccatgcgc attgctgctt caacgttagc tgcgtttagg
    20221 tcttccattt ttaattcagc gatttctctt acttgatcgc tagaaacttt cgcaacttta
    20281 tttttgtttg gttcgcctga acctttttcg attttagctg cttttttcaa tagaacagca
    20341 gctggcggtg tttttgtaac gaatgtgaat gaacggtctt cgtatacaga aataacaacc
    20401 ggaatgatca aacctgcttg atcagctgta cgagcgttga attcttttgt gaatcccatg
    20461 atattgatac ccgcttgacc tagtgcagga cctactggtg gagctggagt tgctttacct
    20521 gcaggaattt gcaatttaac gattttttct actttctttg ccacgagaca tacctcctta
    20581 agtccgtgat gtggttaatt ggagatgcat atttctcctc ccacgtttta tctgatctga
    20641 aaaaatccag acaaataatg tgcaaaacaa tgcacactgg tacagtatag caaatttatt
    20701 tgttttttca agattttttt ctgctatttt tacattttgc ttgaataaac gctaaattta
    20761 ttctaaaaaa acaacaattt ttcgttctca tttcttcttt tatgttacac ttgcgctagc
    20821 atggttcaac agatgaaagc aaacaataac acggtttttt agacccttgt acaaagattc
    20881 ctacataaca aaatgaggtg gagaaaatga aagatttaag gtatagaagt gtctttgata
    20941 ttattggacc tgtgatgatt ggtccaagta gctctcacac tgccggagct gctagaatcg
    21001 ggaaaatcat acgtagtata tttggcgaac agcctgattc tgtagatatt tatctatatg
    21061 aatcatttgc aaaaacctat cgggggcacg gaacagatat tgcattagtt ggcggcctgt
    21121 tagggatgga acccgatgat gaacgtttag ctgattcttt gaaattggca tatgaagccg
    21181 gtatggaagt cttgtttgtt cctaagagtg aaaaagccga acatccaaac tctgtaaaga
    21241 tgcttctaaa aaaaggaaca cgaaagcttt cagtcactgg catttcgatc ggcggtggca
    21301 atatccagat ttctgaattg aatggattca aaatttcttt aagcatgggt actcctacct
    21361 tgatcgttgt ccaccaagat gttccaggta tgattgctaa agtgactagt atactttctg
    21421 agaccaatac gaatatcggc actatgacag tgacacggga atcaaaaggt gaaaatgcca
    21481 ttatgataat tgaagtagat gatcctcaag tagaagaaac ggtaaaaaga ctcaaacagc
    21541 tgccaaatat cgacagcgta aattatttcg attaaggagc taaaaaaatg tttttatcga
    21601 ttgaagaatt agtagatcaa gcaaaagctt atccaagtgt agcagaattg atgattgcag
    21661 ttgaaatgga aatgagtggc cgttcccgta gtcacatcat cgagatcatg gaaaaaaacc
    21721 tctcagtaat ggaacaatca atcaacgagg gaaaagaagg tgttacctcc gtcacaggaa
    21781 ttaccggtgg tgatgcaaaa aaattagatg attatttaaa tgaggcagac tttttaagtg
    21841 gagaaacaat cttaaaagct gtacgcaatg ctgtagctgt taatgaagtc aatgcaaaaa
    21901 tggggttgat ttgtgctaca ccgactgccg gaagcgcggg tgttgttcct ggtgtgctga
    21961 tggctgtccg agatcggctt gatttgacac atgaacagca attggaattc ttatttaccg
    22021 ctggcgcttt cgggttagtc atcgcaaaca acgcttctat cagtggtgca gaagggggat
    22081 gtcaagcaga agttggttct gcaagtgcaa tggcagcagc agctttggtt tgtgcaaaaa
    22141 atgggactcc tcatcaagca gcacaagcag tagccattac attgaaaaat atgatgggac
    22201 tgatttgcga tcccgttgca ggcttagttg aagtcccgtg tgtcaaacgt aatgctttag
    22261 gctcttctca agcttttatc tctgctgata tggcattagc gggtatcgaa agtgtcattc
    22321 cgccggatga agtcgttgct gcaatgtacc aagtcggacg tcaaatgccg tcgattttca
    22381 aagaaacagc agaaggtggc ttagctgtta cgccaactgc taaacgactt gcggaagaga
    22441 ttttaaataa gagggcgtga taaagctcct taatttcgag tattaagaga ttagttatct
    22501 tcataacaaa aaacgaagag aggactaatt gcccttctct tcgtttttta ttaatccatc
    22561 aatttcgtat tttttacttc atcgatcgtt tttgttcctg caagttgcat cgtgatcgac
    22621 aattctttgt tcaggtgttc aaaaacagat gttactcctt ctgccccacc tagattcaac
    22681 ccataaatca ctggtcggcc aatcgcaact aagtcagcac cacttgccag agctttgaag
    22741 acatgctctc ctcgacggac accagagtcg aaaatcactg gtacacgttt gttgactact
    22801 tcggcaattt ttggcaatac ttcaaaggac gcaggacctc catctagttg acgtccacca
    22861 tgattggata cccagatacc atctgcccct gcagagatag cgattactgc atcttctggc
    22921 gattgtattc cttttacgat aactggaaga tgggtgattt ctttgattgt tttgatgtca
    22981 tctggtgtca agccttgttt tgcagctgca taaatttctg cgattccttt tccttcgcca
    23041 ttaccacttg cactttgttc gctatacgca gctaagttag gcattggtaa tggaaattgg
    23101 aattgattga tgacgtcttc ttcacggtaa ccaccgagcg ttgaatctgc cgttaaaatg
    23161 atagctttag cccctgcttc tactgctttg ttcaaaatga actcattgaa tctgtcgtct
    23221 ttactcatat ataattggaa aaactgcggt gcgcctggcg ctgcatcggc tgcgtctttg
    23281 attgtcgtat ttgcataagt gctgatggaa aagattgatc cagcagcagc tactccttta
    23341 gctgtatcag cttccccttt ttcatgtgcc aatccttggg ccgctgatgg cgcttggata
    23401 atcggtgtat ctaattcaat tccgaaaaca gatgtatgca aatcggctga gtcgattccg
    23461 cgtaatatcc gtggcatgat tttctttgta ttaaaagaag tcgtattttc tttcatcgtc
    23521 cactcatctt cagaaccacc gcgaatatag ccaaaagctc ctgcttccat gcgctctttt
    23581 acacgacctt ctagttaggc aatgtttaca atatcgattg gatgttcttc attacttgta
    23641 tgataagtca tagtagatcc ttctttcatc ttcttgatta catataaatc atactaaact
    23701 tacaaaaagt aagcaaacat ttactctcag atacttttat cgctattctt tccaaataaa
    23761 tcgacttaca agctgatcta cttcttggtt ttcatgaagc atactatgag aggcattttc
    23821 acctgtcact actttttcct ctatttcatt tccgcgttgc ttcaacaacg catagaccgc
    23881 taatgcactg tttaacggta ctgttccatc actcaagtct gtttcatcta gttgaccagc
    23941 aatcaagaaa aatcgagtgg ttataggaat attaccgatc atttgctggt aatcttgata
    24001 gcggttagaa acgacagcag gcccctttgc taactcatct gtcagagact gcgcactatc
    24061 atcgacaaaa tcattaaaag gcgcgccaat tgctgttaat gtctgaactt gtggcaatga
    24121 cgtatcctgt ccatacgttc ctaaatagcg tagtgcacta actcctccca tggaatgccc
    24181 cactatgttg actttatcta tgccgtagtt ttctttcaga tacaaaagac aagttttgat
    24241 ccattctgct tgattccact cgttattttt attatcttca aacaatactt ggaccatcgg
    24301 attgtctgct tttccagaca aatctcctgt tgcttgtatt tgtccatctg ttcctactgt
    24361 taaaaccaat tcttttactg cttgctgatt tttttccaaa cgccgcaaca tccctttaaa
    24421 ggaattttct gtcccgctgt agccgtggaa aaaaagtgtt ggaatagtgg ttttttctat
    24481 cactttactg gattctgccg ttttttcttt atcagaaact tcagtagtat ttatcttcgt
    24541 cgtctggcaa ccacttaacg caaacaaact gataaggact aaagctgctg cagttgcacg
    24601 tttgcataaa tttttgattg gttctgtcat acacctcttc ctttccatat agaaaaaaga
    24661 aagacttgaa aggccaatca tatgatcgac atttcaagtc tctttattaa tcgattttat
    24721 ctacttgatc gaaatcaagt tctgtactgg tttcacgtcc aaacatatcg atgttgactt
    24781 tcaatttttc tttttctccg tcaacttctg ttacttgtcc ttctaatcca gcaaatgcgc
    24841 cttcgatgat tttcacgact tcgccaactt ctacttctag atcattttgt cgcaggctca
    24901 taccgataga acgcaagata tgattgactt cttctggaag taatggtgct ggtttgcttc
    24961 cggctccgtg tgaaccaacg aatcctgtca caccaggtgt gttgcggaca acataccatg
    25021 aagcgtctgt catgatcatt tcaacaagta cgtatcctgg gaatgtttta tgaacgattt
    25081 ctttttcttt cccatttttg acttcagttt ctttttcttc aggaacaacg acacggaaaa
    25141 taaagtcggc cattttcata ctttgcgcac gagattcgat atttgctttt actttgtttt
    25201 catatcctga atatgtatgc aagacatacc agtttttttc aaaagattcc attgaaggct
    25261 cctcatttca ttgtaaaata aaaaaacctc agtacacccg aagtttttct ttcgcttcat
    25321 tatagcacta aaagtacgtt gtggctagcg agttatttta aaatccagcc aaataagctt
    25381 tggatggctg tatccattac gtaaaacatc aatccgaaaa taatagaagt ttcgatgact
    25441 actaacgtat ctttacggag ttgttttctg cttggccaag ttacttgttt gatttcatct
    25501 tttacgcttt ttagaaattt catgagacaa cctcccttgc tactgtttat ttcgtttctt
    25561 tatgtaatgt atattgatta caatatttac aaaacttatt gatttccaaa cgttcgccgc
    25621 tttttccttc actgactgat tttgtgtagt tgcgagaccc acaaacggaa caagcgagtg
    25681 ctgctttttt ctttgccatt tacttctgcc cccttgctga gaatcagact tatacttcat
    25741 aacagtatca cgtaactttt tacttgtcaa tttgtgaaat aaactatcta ttgttttgga
    25801 taaaattatg atatgattaa tttgaaatta agctaaaatg agacaattgg aggtatagcg
    25861 atgctattaa aaacacttgt atataagaaa aaagatctga caaccgttac agagactagt
    25921 acattagaag aagcattaaa aattttagaa acttccggat accgttgtgt gccgatctta
    25981 gattcttcag gtaatatttt ccgtggaaac atttacaaaa tgcatatcta tcgtcataaa
    26041 gcaaatggcg gtgatatgac gcttcctgtc actcatcttt tgaaaaacgc tacaaagttc
    26101 atttacctgg atacttcttt cttcaaagta ttctttacga tcaaagagct tccttatatt
    26161 gctgtccttg acagtgaaaa tcatttttat ggtattttga cacatagtac gttgcttaat
    26221 atgctctctc aatcttggag cgtagaacaa ggaagctatg tactgacaat tgcttccaca
    26281 ggaaagcaag gagatttggc tgctattgca aaaatcattt caaaacacag cagcattgcc
    26341 agctgtatta ctcttgatat cgaaaaagac gaatacattc gacgtacatt gatcacgcta
    26401 ccggctaaca ctgaagcgaa agtatgtgaa acgatcgtca accacttaga gaaaaagaat
    26461 tataaagtgg tagaaattga aaatttgcaa aaccaagaag cataatcaaa aagcgaaaaa
    26521 agaaaacagc taatctgctt tcttttttcg ctttttataa ttagacacgc ttttcaaaat
    26581 caagcgcgcg atctaaataa tacatcaatg gtgctgaaac agccatgacg ataaactcac
    26641 ttaatgcaag cgtgccatag gttgtccaaa atgcttggcc acctgttgga actaacatat
    26701 aagcaatcag tcccatgctg atggtaaaga agatcgtgtt caatactaaa cgcatcttta
    26761 catttttcac tttgttttgc aataaagctg tcaggcctaa agaaagcaat gtttggccgc
    26821 caccaaaaac cacatccatg ataccaaaac caaagaaggc attatagacg atgaccccgc
    26881 ctaaaactcc ccaaagcaat ttacggttaa agacaactaa atgattcaaa ctttctgaaa
    26941 tacgaaactg gatcggccct gaggatacag gcgcaactaa aatagttaac gctagataaa
    27001 gagccatgat gatgccattt acaacgatta cggataaccg ttgtctgctt ttcgtttttt
    27061 gcattttctc tcctcttttc tcctagtttt tttaacgcgg gatggttgat gaaccgcggt
    27121 tatgtgaaac aaacaataat tataacagac ttttcattta tttcaatccg tcttatctgc
    27181 ttttaaaaaa gcaaaagctt aaacaatgta aacgtttgct aaaaatcgtg ggatatggta
    27241 taaagtaagt gtaaggggtc ataagaattc ccagtaaagc agacgaagta ggatctgcaa
    27301 gaacagaatt gttgtgaaac ttaaataaat aaaaaaggat gtgggaattt gagcaacctc
    27361 ttactagaga acggtctagc aagcagctga agatctaagt ggacatgccg aaccttggaa
    27421 cttctcctta cgtaagtaat ggatcatgcg cttgctaggc ttttttgtgt ttttcggtct
    27481 tcggaccttt ttcattttcc tagacttctg ctataataac caagaattaa ttttgtaaca
    27541 gatttttttg aaaaaacaag tttctttcat tcaaaaaata gaaaaagctt gctaattatt
    27601 ggttaaccag caaacaggag tattaaaata tcttgtttta ttgaatagca ggaggaaatc
    27661 atgaaattcc attatcatat attgatcaat ccatcggcag gcagcggaaa tggctataaa
    27721 gtagcagaaa gaattttacc ggtattaaaa aataagcata ttgactatac acttcattat
    27781 agtgaataca aaggacacga tgctgagatt gctgaaactt tggcaaaaga aacattgatt
    27841 ccttggatag aagaagaaca gaaaacaatc gatactttcc cccttttgat catcgtagga
    27901 ggtgacggca ccttacatca ggtacttgat actttctatc agatggaagt agaattccca
    27961 gttgcttata ttccagcagg ttctggagat gattttgctc gaggggcagg ccttccaaaa
    28021 aatcccaaaa aaggacttca gctgatttta gcagctcaat caccagaaaa agtccacata
    28081 atggcttatg aagaaaaaat aagtgaaaaa aaaggaatag ctgttaataa tttcggtata
    28141 ggattagatg cagctatcgt ccatgcgaca aatcattctt ccacaaaaaa gcgattgaac
    28201 aaatacaact taggatcatt ttcgtattta ttctctattc tccgtgcttt attcactcaa
    28261 aaaggatttc caattctggt agatgcagga ggaaaacaat taagtttttc aaacgcattt
    28321 ttatgtacag caacgaagca tccttttttt ggcggaggaa tcgcgattgt tccaactgct
    28381 gatgcgtcta aaccagtcat tgattttgtc gtggtcgaac gaatcaattt ctttaaaatc
    28441 ttgtggctca ttcttttact tatacagaaa aaacaattga aatcgaaata tttccatcac
    28501 tacacaacaa acagattacg tatcgtttca acaacaccgc aacatggtca agaagatgga
    28561 gaagaaatgg aaaaacgacc ttttgatatc acaataacca caactaaaca gttgttttgg
    28621 tgttaataaa agaggttttg tcagaagcta catctggaac accgtttatt cggaaaaaag
    28681 gactgtgaca cgacttttgt cacagtcctt tttttactat gcagttaatt ctttgcccaa
    28741 ttgggttgcc atcgatagtt tctttcttta cccaaaataa attggatcat tgaaaacacc
    28801 gcagcaaaag caactaagac acaaccattg aaccaaaaag attctgcaaa tgtttgattg
    28861 taactgagtg tttcactgat caagttatta ttttgaacaa accaatatgt tggtgtgaat
    28921 gccgctattt tgctaaccat ttctggcaag tattctgctg gtacaaacac cccaccgata
    28981 aagcaactgc ctgtgataaa aatatctttg atcccaccgc tggtttctga gttttttacc
    29041 aatgaagtga tacaagccga aaagctaatg atcggcaata aaaacaagaa agtatttaaa
    29101 atatgatacc ataccgttat atcccacgag gtgtggatca ctaacagaac cattagaagt
    29161 aagaagccac tgaacaacag cagcgagtaa ctaatcaaac taaaggttac tttgcgattc
    29221 aagtttcgtt tggtaatggg cgcactctgg tttcgtttac tgatctcttt gcgattaaat
    29281 gctagattga tgacgctgaa accgctaaaa atggatagaa acaacccata agacaagaaa
    29341 ttaaaggttg tgcccgtcaa cagctttttc atccgctgac tatatcccgc acttagctca
    29401 acttctccag taaccgagag tgccatttgt gtctgttcca tagctgcatc gattgtttta
    29461 tcttcttctt gaaacagaat cagtgtttgc aaaaaggtgt tcacttgctg tgtaacaact
    29521 gttttagaaa aggcatctgg gcgactctgt atcttgatcg tcggcatctt tcctacttcg
    29581 acttgttcgg taaagtctgc aggcagatgt aagataatgt ttacacgatt aaaataaaga
    29641 gcatcatcga tttctttttg tgaggttcca tccaatgtaa cgactgtttc cttgtcattc
    29701 aaatatttac gaaggccatc gactacaggc gactcttctt cactaatcaa ggcgattttc
    29761 gcatcttgca gagaggtatt ttcaacatca atattttgcg caaaaaagaa tgtggcaaca
    29821 acagtgataa ttacacctat cagtaaattc gatttatttg ctttaagcaa tgtccaaatc
    29881 gttttataaa gcgtcataac gcacccctct ttccatccaa gcatttccta acgcaaaaag
    29941 gaaaataaat ccgatcaacc atagaagatt ggtataaaaa ctagccaaat cagtgtagaa
    30001 ataaagttt
//
LOCUS       DACGDM010000024        29239 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.024, whole genome shotgun sequence.
ACCESSION   DACGDM010000024 DACGDM010000000
VERSION     DACGDM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.024"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..843)
                     /locus_tag="IXR05_001202"
     CDS             complement(<1..843)
                     /locus_tag="IXR05_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4259739.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDS"
     gene            complement(1067..3007)
                     /gene="thrS"
                     /locus_tag="IXR05_001203"
     CDS             complement(1067..3007)
                     /gene="thrS"
                     /locus_tag="IXR05_001203"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAQ4259740.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3344..3523)
                     /locus_tag="IXR05_001204"
     CDS             complement(3344..3523)
                     /locus_tag="IXR05_001204"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAQ4259741.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3570..5393)
                     /gene="cadA"
                     /locus_tag="IXR05_001205"
     CDS             complement(3570..5393)
                     /gene="cadA"
                     /locus_tag="IXR05_001205"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4259742.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5671..7950
                     /locus_tag="IXR05_001206"
     CDS             5671..7950
                     /locus_tag="IXR05_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4259743.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8043..8690)
                     /locus_tag="IXR05_001207"
     CDS             complement(8043..8690)
                     /locus_tag="IXR05_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259744.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8869..9588)
                     /locus_tag="IXR05_001208"
     CDS             complement(8869..9588)
                     /locus_tag="IXR05_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4259745.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9719..10870)
                     /locus_tag="IXR05_001209"
     CDS             complement(9719..10870)
                     /locus_tag="IXR05_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAQ4259746.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11087..11827)
                     /locus_tag="IXR05_001210"
     CDS             complement(11087..11827)
                     /locus_tag="IXR05_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4259747.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11831..12154)
                     /gene="rsfS"
                     /locus_tag="IXR05_001211"
     CDS             complement(11831..12154)
                     /gene="rsfS"
                     /locus_tag="IXR05_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAQ4259748.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12211..12804)
                     /locus_tag="IXR05_001212"
     CDS             complement(12211..12804)
                     /locus_tag="IXR05_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4259749.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12788..13435)
                     /locus_tag="IXR05_001213"
     CDS             complement(12788..13435)
                     /locus_tag="IXR05_001213"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAQ4259750.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13448..13759)
                     /gene="yhbY"
                     /locus_tag="IXR05_001214"
     CDS             complement(13448..13759)
                     /gene="yhbY"
                     /locus_tag="IXR05_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAQ4259751.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13775..14884)
                     /gene="yqeH"
                     /locus_tag="IXR05_001215"
     CDS             complement(13775..14884)
                     /gene="yqeH"
                     /locus_tag="IXR05_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAQ4259752.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14881..15408)
                     /locus_tag="IXR05_001216"
     CDS             complement(14881..15408)
                     /locus_tag="IXR05_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAQ4259753.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15588..16373)
                     /locus_tag="IXR05_001217"
     CDS             complement(15588..16373)
                     /locus_tag="IXR05_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAQ4259754.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16366..17235)
                     /locus_tag="IXR05_001218"
     CDS             complement(16366..17235)
                     /locus_tag="IXR05_001218"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAQ4259755.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17236..18615)
                     /locus_tag="IXR05_001219"
     CDS             complement(17236..18615)
                     /locus_tag="IXR05_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAQ4259756.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18623..19042)
                     /gene="fabZ"
                     /locus_tag="IXR05_001220"
     CDS             complement(18623..19042)
                     /gene="fabZ"
                     /locus_tag="IXR05_001220"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4259757.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19067..19543)
                     /gene="accB"
                     /locus_tag="IXR05_001221"
     CDS             complement(19067..19543)
                     /gene="accB"
                     /locus_tag="IXR05_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAQ4259758.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19546..20781)
                     /gene="fabF"
                     /locus_tag="IXR05_001222"
     CDS             complement(19546..20781)
                     /gene="fabF"
                     /locus_tag="IXR05_001222"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAQ4259759.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20800..21537)
                     /gene="fabG"
                     /locus_tag="IXR05_001223"
     CDS             complement(20800..21537)
                     /gene="fabG"
                     /locus_tag="IXR05_001223"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAQ4259760.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21549..22466)
                     /gene="fabD"
                     /locus_tag="IXR05_001224"
     CDS             complement(21549..22466)
                     /gene="fabD"
                     /locus_tag="IXR05_001224"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4259761.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22573..22797)
                     /locus_tag="IXR05_001225"
     CDS             complement(22573..22797)
                     /locus_tag="IXR05_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4259762.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22850..23812)
                     /locus_tag="IXR05_001226"
     CDS             complement(22850..23812)
                     /locus_tag="IXR05_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAQ4259763.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23822..24262)
                     /locus_tag="IXR05_001227"
     CDS             complement(23822..24262)
                     /locus_tag="IXR05_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4259764.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24568..25533
                     /locus_tag="IXR05_001228"
     CDS             24568..25533
                     /locus_tag="IXR05_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4259765.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25590..25820)
                     /locus_tag="IXR05_001229"
     CDS             complement(25590..25820)
                     /locus_tag="IXR05_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAQ4259766.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25906..26793)
                     /locus_tag="IXR05_001230"
     CDS             complement(25906..26793)
                     /locus_tag="IXR05_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAQ4259767.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26882..28105)
                     /locus_tag="IXR05_001231"
     CDS             complement(26882..28105)
                     /locus_tag="IXR05_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4259768.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28122..29201)
                     /locus_tag="IXR05_001232"
     CDS             complement(28122..29201)
                     /locus_tag="IXR05_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4259769.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
BASE COUNT         8095 a         6414 c         5044 g         9686 t
ORIGIN      
        1 cgaatccata aaatattctt ggattgcttc tcgtgttttt ttcacttttt cgctaagctt
       61 ttcgttttta gccatataga aataaaaaat gatatcgatc gtagcaaatt gggccaaaag
      121 tgaattagtt gccgcacttc gattcgtgat ttcttttggt ctagatgttt gtacgagtac
      181 atcggctatc ttgctaagcg ggttatttcc aaattgcgtc aacgcaatga tttcgatatt
      241 catgcttttc gccagctcgg ctaatgcgac tacatctgca cttctacctg agtttgaaac
      301 aagccaaagc actttctttt tctcattgct gacaagttgc gggagcaaga cgtggatatc
      361 tttttcaaaa atgattggct taccgacacg agaccatttt tgcagaatat cttctactac
      421 taaagaagag gcgccaaccc catataaaaa aacagtctct gccgattcca aacactctac
      481 gactttttgg atcgtttctt cttctagaat atctactgtt tcttttatcg ctacttgtgc
      541 attgttacca agtttgtttt tgatagagta aaaggactca tttgcttcta tatcactaaa
      601 accttcatcg attccagtct gtagttctgt tgaaatcgtg attttgaagt ccgtcagact
      661 ttgaaaaccg atttttttgg aaaaacgtac aactgtcggc gcactcaacc cggaagcttc
      721 tgctaattca ttagctgtca ttgtagggac cttctcaata ttaccgataa tgtagttggc
      781 caactttttt tctgctgaag aataatcttc catcatactt tcaatacgac taattacgct
      841 cataagttcc tccacccttt taatgatagt ctatgtaagt ataccatatc agacccttat
      901 tcacggtcgt atactggata aaaaacaaaa aaacaatccg cccaacagaa tatcttatcc
      961 catcaatccc acagattcta ttgagcatct gtgtctttga ggaatacctg ttatctattg
     1021 ttcggattgc tttctatcta ctactttttt acaggaaatt tacctattag ttttctctgc
     1081 tgtaattttt gacttctgct tccatagcat caataaagat attcaaatct tctacagctg
     1141 tttctttact tccataacga cgtacgttca ctgttgcatc ttccaattcc ttgtctccaa
     1201 caactaattg gtaagggatc ttttgtgttt gagaggcacg tatcttatag cccatttttt
     1261 cattacgatc atcaacttct acacgcaacc ccttcatttg caaacgttct ttgatttcat
     1321 aagcataatc gccatgtgca tcaacagaaa cagggatgat tgttgcttgt ataggtgcca
     1381 accatgttgg aaaagcgcct ttgtatactt ctgttaaata agcgacaaaa cgttccattg
     1441 tagaaacaat tccgcggtgg ataactactg gacgatgcgt attttccccg tcttctccaa
     1501 catatgtcaa atcaaagcgc tctggcaata agaagtctaa ttgtatagtt gataatgttt
     1561 cttctgtacc aagagctgtt ttgacttgaa catctagttt tggtccgtaa aaggctgcct
     1621 cgccttctgc ttcaaagtaa tctagttcta attcatccat agcggctttc agcattgctt
     1681 gggctttttc ccacattgcg tcatcatcaa aatatttatc tgtattgttt ggatcgcgat
     1741 agctcaagcg gaaacgataa tctgtaatat tgaagtcagc atatactgcc accatcaatt
     1801 caagcgtacg tttaaattca tctttgattt gatcaggacg aacaaatgta tgaccatcat
     1861 tcaacgtcat ttctcgtaca cgttgtaaac ctgacaaagc acctgatttt tcatagcgat
     1921 gcatcattcc taattcagcg atacgaattg gtaattcacg ataagaatgg atcgtgtttt
     1981 tgtagaccat catgtgatga gggcagttca ttgggcgaag aacaagcatt tcgccatctc
     2041 ccatatccat tggcgggaac atgtcttctt gataatgatc ccagtgtcca gatgttttgt
     2101 acaactcaac atctcccatt attggtgtat atacatgttg gtaacctaga ctaacttctt
     2161 tgtctacgat ataacgttcg atcgtgcgtc ggattgttgc cccttttgga agccagaatg
     2221 gcaaaccaga acctacttct ggggaaacca tgaacaagtc aagttctttt cctagtttac
     2281 gatggtctct ttcttttgct tcttcacgga gacggatata ttctttcaaa gctttcttgt
     2341 caaaaaaggc tgtcccgtat acacgttgca tcatttgatt gtttgagttt ccacgccaat
     2401 aagcacctgc cactgataat aatttaaata cttgtatacg gccagtggat ggaacatgtg
     2461 gtccacgaca caaatcgatg aattcgcctt gttgataagc agtaatcact tcttcttctg
     2521 gcaattcact aatcagttct actttgtacg gatcacttgc aaaaatttct aatgcttcct
     2581 gttttgaaag aacacggcgt tcgatcggca gattttcttt gacgattttc atcatttctg
     2641 cttcgattgc cggcaaatct tctgcagtta cttggttttg tccattatct gtatcgtagt
     2701 aaaaccctga atcgatagct ggtccaacgc caaagtggat atttggatag aggcgacgca
     2761 tggcttgggc catcaaatga gctgctgaat gacggactaa gccaagtgca tcttcatggt
     2821 ctggtgtgat gatctcaata cttgcatctt cctcgattgg acgagtcaaa tcaacgagtt
     2881 ttccgttcac tttaccagct aaagcttttt ttgctaagct ttttgaaatg ctttcagcaa
     2941 ttgccaatgt tgttgttcca gactcaaatt ctttgactgc accatctgga aaagtaattt
     3001 ttatcataat agtttcctcc ttgaaatgtt ttgattgatc agatcatcaa gctgaaaaac
     3061 aaaaaaatcc tagcatctct tgaaaagaga tactaggacg aaaagttcgt ggttccacct
     3121 aatgttcaaa cgcaaatgcg ttcctcaagc gttgtaacgg tccgaccgcc cttgcttcaa
     3181 caagggtttc gaaagtggtc atcctttggt tttctcctgg aaaagtttca gcctagcttt
     3241 tcctctctta tcgaagactc tcaaattcag ttggctttct catcaatcaa ttatgtgttt
     3301 atttaaccac taataaatag aaaaatcaag tgggaaacta aacttatttt ttccattccc
     3361 catttacacc gtatgttcct tttttcatct cattgatgat gacatggatg tgttcttttg
     3421 gtgcctgcgt gtttttatga acagcttccg tgatatcttt catcatattt tctaattgtt
     3481 ccggactgcg accttctact aattcgacat gtacgaatgg cataatgctc tctcctcttt
     3541 ctgatcgttc ttttttcaac tcgattctat catactatgt ttgtcttggg tactgaatca
     3601 ggaaaaatgg ctggatcttt ttttgctctc aaggcactca aaatagagac cgtatccacg
     3661 acttcttgca aaacagctcc gaataatgcg gggattagtc ccgtacttgc aattaacatc
     3721 aaaaaaatac aaataaagat gccaatcagt acagactgtt tcgctattct catcgtatct
     3781 cttgaaatca ctactgcttt tgctacacgc aagagatcat ctttcaagat gaccgcatct
     3841 gcactttcac tagcagctgt agaaccatga gcccccattg caataccgat atctgcagca
     3901 gcaagtgctg gtgcgtcatt cacgccgtct cctaccatcg caacaggtct ttgatcttta
     3961 gggatacttt ctaaaatggt cagtttatct tgaggcaagc tacgggcatg tacagaatct
     4021 aattggactt tttctgcaat cgtttgagca atggcagatc catccccggt gatcatcatc
     4081 aaatttttca catcaagttt tcttagctcc ttgattgtct ttgctgcttc tgggcgaatc
     4141 tgatccgaaa ataggatcgt tcctgcaaaa gatcgatcaa ttgttacata gattgctgta
     4201 ttggacgttt ctatttcttc agctgaaaca aaagaggcac gtccaatctt tacttcatga
     4261 ttattgacta ctgcttggat tccttgaccg gtcacttctt tcagttgact aacaggatac
     4321 agttggctgt ttttcacgtt gttcactaac gaacgagcta agatatggct agattcctgt
     4381 tctgcactag ctgcatacag aagtagctct tcttttttta ttccattgac tggctgaatc
     4441 gcctctactt ccaatatccc tttggtaagc gttcctgttt tatcaaaagc aatcgttttt
     4501 gtacgtgcga gcttttcaat cgttgttcca gtttttacaa cgatcccgtt tttacttgaa
     4561 cggctcattc ctgcaactaa agcaatgggc gcagctagaa tcagtggaca aggtgatgcc
     4621 actaccagta cctcagcaaa tcgtaaaggg tcttttgaga accaccaaga aataccaccg
     4681 atcaaataag caatcaacgt gaaagggact gcataacgat cagctaaacg gacaaatcgg
     4741 gcaggctttt cttttgattc ttcgactagt ttaataatca tttgatactg gctgtctgcg
     4801 gcacgttttt cagcgatcat ttggatcgat ccgtctccat ttaaagaccc tgacataatc
     4861 tgatctccag gtttcttggt ttccgggcgg gactcacctg tcaaagaaga ttcatcgacc
     4921 gaagattctc ctttggtcac tcgaccatct gcgggtacaa gttcgccagg cttgactagt
     4981 aactggtcat caatatttat ttcatcgatt actatatcct gcaattttcc ttctttgaat
     5041 cgatgggcaa ttcttggggt gttatctaac aaagactgca gttctttacc cgctcgttta
     5101 ttcgcgtaat cctctagact atctccgccc gtaagcatga tcaatatcat caaactagcc
     5161 cagtattctt tgacggctaa tgttgcaagg attgcggtaa tcgctaatac atctacgcca
     5221 tatcttcctg aacgtaacgt cttgatcatt tccaaaaaca tcaagaaggc gagaatccct
     5281 ccagtaaatg cgacaatcgc aaatgcaagg gccggctggt gaaaaacaaa ttcacttaat
     5341 aaagctatcc caccaataag caaagtaagt aaaaattttt tgaaatgtgt cattgttttt
     5401 tctcctcttt tatgtgactt agagaggtta gtaataaatt tccagctgcc tctttcatct
     5461 taagcatagt ccttgactag cactttttaa aacaataggc cttaattgaa aacaactatc
     5521 actatcagcg tttccaaaat tcatcagttc tacaaacaaa aatattcagc aaggattact
     5581 ttttcgattc atcagttaaa aagtaccttt tttcgaaaaa ctatgctata cttttaattc
     5641 gttatttacg gcggaaggag caaacatgcg atgaatgaga aacaactaga acaaacgcac
     5701 gtggatgaaa cgatcgaact aatccagatc gaacaaaata tgctggatac aaaacaacaa
     5761 gaattgactc aggaaatgaa tcattcgaca aaagacacag ctaatcacaa gattcgagct
     5821 ggttccaatg aagcttttta tgaatctgct gttgaatatc gccaacatga gcaggaattg
     5881 cttttgaaat accatactct tgaagcacag caaaaacgcc tgcaaacgtt gtctgtcatg
     5941 aaagatagtc cttattttgc ccgtatcgac tttaaagaag accgtgaaac agaaacatta
     6001 tatctaggta tcgcttcttt aagagatctg gcagaagaaa caatcgttat tgactggcgc
     6061 gcaccaattg ccaatcttta ttatgaaggt gagattggtc ccgcatttta tgaaactgaa
     6121 acagatagaa tagatgtcga tctgcagttg aaacgacaat ttaaaatcca agaaggacgt
     6181 attttatcta tggtagatac gtcggaagta atcaatgatg actttttgct agagatattg
     6241 gatgaatcat caagcaacca tatgaaaaac atcgtctcta cgatacaaaa agcacaaaat
     6301 gcaatcattc gggacacaac aagtaaagta atgctgattg aaggaatcgc cggaagtgga
     6361 aagacatccg ctttgcttca acgtattgct tttctgttgt atcataatcg caagtggctc
     6421 gaggctgaaa acgttcttct attttcaccc aaccatttgt tttctgatta catctcgact
     6481 gtattgcctt cattaggtga aagcggcgtg cctacacaga cattcaaaaa ttatttggtg
     6541 cagctgctgc cagagttttc tttactagat gaacagcaac aagaaagtgg ttttttgcta
     6601 ggggaaaaag atccgataca agtgatgaaa agcggattga ccttagtcga tcagattgat
     6661 cgctatatcc aaggcatcac aaactacggt cccttgttcc gtgatatgaa aataaatggc
     6721 cgtacgatcc tatcaaagga atcgattcgc caatggtata aagaaacaaa tgaacaatta
     6781 cctttacatc atagactttc tctattacaa acgaagctcc tgaaaaaatt aggcggtctg
     6841 caaaaagacg aaacacgtca gcaatgggtc aaagatctgg cggaagaaca gctccaagaa
     6901 ctatacgcaa cagatccaaa tcttgaatat acagaacaaa aggagcgttc attacgtaaa
     6961 aaactggcca accaaatcgt acgtaaaaga ttccgtcgaa tccatcgagg gatcatgaat
     7021 tatcaatttg tcaatataac gaaacaatat ctccactttc tacaaactgt gccactttct
     7081 cttctaacac gacataaaat cagcgagacc aggtggcagg aacatttgac aactgttcgt
     7141 acacacttgc gtcaaagaga attgcgtcaa gaggatgctg tactattctt tttactgatg
     7201 cgccgaacat atccagtgac ggttacacac aaagctcgct atatctttat tgatgaaatg
     7261 caggatttcg caccatcaca agtggcattg ctgcaagcct tgttcccaaa agcaaatttg
     7321 actttctgtg gagatctaaa tcaaaatgtc tttggaaatg aaacgatcgt tggatcattg
     7381 gaagaccttt tcgtggaccg tgaagtcact cgtttccaat taacgacaag ctatcgctcc
     7441 acaaaagaaa tcactgattt tgctaatcat tttattgtga aagaacatca agtagaaaca
     7501 acagcaagaa aaggagacct tcctttgctc atccaaggaa caacagatga tatcaaattg
     7561 aattggttag cagataccat tcgaacgact cagggaaaag cccggtattg gcgtacagca
     7621 atcatagcta aaacacaaga agaatgcgaa gctctttatg ctcaactgcc agacgagttg
     7681 aaacaacaag tccagctgat tttaaatgag agtgacttta tgaagcgttc cattatttta
     7741 cttccagcct ttttagcaaa aggtctggag tttgaccgag ttttcttgtg ggatgtagat
     7801 gcagaacatt tttcttctca gcaagacaaa ttgatccttt acaccatgtg tacacgtgcg
     7861 atgcatgaat tgaccctttt tacctccaat aatgaaagtc ctttgttaaa caatatggat
     7921 atttcatctt atgagaaaaa agtactgtaa gtaaaaagac aactgctatc attaatgtta
     7981 gcagttgtct ttttatttac aataataatt gcagaaaaag taattcaatc atttaaggtc
     8041 atttattcta tatataaatc caaatctgtt tcaggatatt ttaatttgac aagcgaaata
     8101 atcattttca gttcttccat gttttctgga tattctgggt caaatacctt gctatgacgg
     8161 ccaatcccgc cattgtcgat caatcggtaa attcgattcc attcaatgaa ttggtcaatt
     8221 gattggaaat tgctgattgg atagccgcca caatccaaaa tctctgatac acgaaatgct
     8281 aggtatgcac tatcgatcac tttatttttt ttcgtgtcta tcttctcatt tctttcgata
     8341 agaatttttt caggacgatg tttcaagctc cactctaata gtagaaagaa agcctccatc
     8401 cgatactctt cttcaaataa ccgaaaggct gaatcagaac gacgaaaaag cagcggaatc
     8461 agataatttt gtctataaat cagcattggt gcgcggtcca ccatacactc taaataacgg
     8521 ttcagatacc ctgtaccgac atagtttcct aatcgatagc cttcaacgcc gaatcttgcg
     8581 tatttttgcg ctaattttga acaatcagtt acgttcacag ctaactcttc tactttgcgg
     8641 taaccgctta agatacgttc aaaaggttct aaagtgattt ttgcttccat attcttcccc
     8701 gtccatcttc cacatacttc atatcatttc acatgatact tatgctctca tcataccaca
     8761 ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa gacaatctgt tagtgagatt
     8821 gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa ctggttgctt agtcttctaa
     8881 tgccacatta tggaacacat gctgtacatc ttctagatct tccagtgcat caatcatttt
     8941 ttcaaatgtt tcttgatctt ctggagatag tgttacctcg ttttgaggga tcatttggat
     9001 ctcagcgatt gaaaaatcag tgattccttt ttcttttaat gcttcttgta tactatggaa
     9061 atccgctact tcaccgtaaa cgatgatttg tccttcttct tccattacat cgcgaacatc
     9121 gatgtctttt tccattaggt attcaaggat ctcgtcagcg tcttctcctg caaaagcaaa
     9181 gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa acacccatgt tcccgccatt
     9241 tttcccaaat gctgcccgta cgtctgctgc tgttcgattc acattgttcg tcaatgtatc
     9301 aacaatcacc attgagccgc ttggtccaaa tccttcatag cgcaattcag agtatgtttc
     9361 atctcctgca ccttttgctt tttcgattgc tcggtcaata atatgttttg gtacattata
     9421 agttttagcg cgatcaatga cgaaacgtag tttttggttt gcatgcggat caggatcacc
     9481 tgattttgct gccgcgtaga tttcaatccc aaattttgca taaatccggc tattattagc
     9541 atctttagca gttttctttg ctacgatatt tgcccattta cgtcccatat tttcacttcg
     9601 ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt tccattatac ttgtgaatca
     9661 cgattctgtg aagctttttt tctttcttcc ttcattcttc tcatttttag tcaattatct
     9721 atactcggat tgggatttgc ccgaaattct gttccggaat attgcctccc aattgataga
     9781 tttgatcact tctaactaac agttccgctt cttgtgcctc tttttttccg attcgggaat
     9841 aaatagaaat ctcttttttt tcttttaaga atcttcttcc agcatcggta aatccaagta
     9901 gtcgaagata atttttattt tgttggacag gaatctcttg ctttttgata ttcagcaaga
     9961 cataacaaga taatcgttgg atccgtgtcc atgtatatct ttttgttttt acctttgaca
    10021 caaaatcctc aaaactatca gcagttgcag ctgctgtttt catgcgcgat tctattcctt
    10081 cggtcatctg atagatatct gtcagttcca gcaaagtaga agataacaac cgataacgca
    10141 aatacggcca ataagattcc caagtctgca gcgaacaagt tgaaagatct tcttctgtct
    10201 gaggcggcac aagtccagct attctttttc cttcttctaa cgcatggcga atggctgttg
    10261 cactggctat cctctgatct gtgatgattt tttcatgata gcctgcactt ttacgtcgga
    10321 tcggatgtaa ttccataggg tggacatact tggcattttc ctttgcataa cttaatccca
    10381 agatatgatt tggcgaagaa aaatcaagcg taatatcggg atacagactg cgaaaaacct
    10441 cagtcatttt ttgcggataa ctatacgttt gatcagacag ttcttgaaat gcctcttcta
    10501 tcctatcttg attctcttgg acaaagcgtc cgaaactgct gtaatcaaac gaagtctctt
    10561 cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg caagattttt actgcacctt
    10621 tagcaaaata gtcagctgac tgaaccgccc attcgacggg aagctccact actaaatcca
    10681 caccattttg taaagcttca ttcgcgcgat gccatttatc gatgatagcc ggttcgcctc
    10741 tttgcaaaaa attcccgctc attacagcaa tgacgacctc tgctcctgtt atttttcgtg
    10801 ccatttccac atgatagcga tgtccattgt gaaaaggatt gtactctacg ataatcccgc
    10861 agcttttcat gcgcatcctc cttcatagtt atcgataaaa aagaaataga gacaagtaaa
    10921 aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac tattctcgca aacacaatac
    10981 ttctgcgacg aaaagctgca ctgcaagagc aatgcctata tcgttcggat atataattta
    11041 tgttgaagat ttattctttt cttgttaact cgagcaggca aaaccgctag tctttgtatg
    11101 ctacaaagaa ccagcgcttt gatttctctg atgctgcttc gtctgtaaaa tcagaaaatg
    11161 cttcgacttt cgaaaagccg ctgttttcca gcattcttaa ataactttcc aatggatagg
    11221 tacgctcttg atgtagttca tcttcacgaa taaatcgacc agacccttct tgttcttcaa
    11281 cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct tcctggataa ctatcccaca
    11341 aaaaagcaaa attatcccct tgataatgat agctatattc tggaaaaacc tcatctactt
    11401 gataggtgga gtgtacgtca aataaaaatc ggccattttc ttctaacgct tgatagactt
    11461 catcaaacac ttgctgtacc tcttgtctat ttttcatata gcacagcgaa tcagaaaaac
    11521 aggtaattgc ctgatattgt ccgatttctg ataaatcgag catattgcct tccacaaatt
    11581 ggatcgatgc gtcttcttca tatgctcgct ggctggcaat catcaacatc tcttctgaaa
    11641 ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc aaccgctaat gctccagtac
    11701 cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa atgacgtttc gaaaaagcta
    11761 accattgctg ataaagtgtt tcgtccatca cttcatcgta aatgaaagca aatgtttcat
    11821 aagccatatg ttaatccaac cattcactaa gatcgactag cggagcatct gaccatagtt
    11881 tttccagatt atagaaattt cgttctggcg catggaaaac atgtacgatc acatctccaa
    11941 gatcgatcaa tacccatttt ccgccttctt ttccttcaat acgttttact tcatatttgt
    12001 tttcttcttc tttatcaatg atttcttctg taattgcgtt gatttgacgt tcgctatttg
    12061 ctgaacagat catgaaataa tctgccaaca aggaaacatt tcgaacgtct aaagcgataa
    12121 tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat ttttaattgt tctttactat
    12181 ctatgatgat ttcctcctaa tatgagcagc ttattttttt gctacccagt aattatatgt
    12241 ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc aaatgggcca atgtatgttt
    12301 tgtttcaaat gctacagctt cgtctagatc agcccatgca atggctcgtg catcttgtac
    12361 cccaggaaaa tctcgacctg gttcaatata gtctgctaca taaatgattt tgtcaaggag
    12421 actcatctta gcagccccag tcgtatgcac ccggattgca tgaagaatct ctgcatcggt
    12481 gattcctaat tcccgctcta caaacgaagc gccaacaaga ccatgccaga ttgcattatt
    12541 ataattcaat aactccggat caaaaccgtc tcttacgatt accattttga actcctcatc
    12601 tggtcgttct tttgcataat catgtgtcaa tgcagcaata ctagcttttt caggagaagc
    12661 accgtatttt ttggcaagag ccacggctgt ttcttctact ccaagcacat gcttgaagcg
    12721 ttgttcgctc attctcatct gtattttttg catcaggttt tctctagaat aagcagtata
    12781 ttcattacta tagtccatat tcatacaacc cttcattttg aatataatca attactttat
    12841 ctggaacaag gtagcggata gaacagcctt ctttgatctt ttgacgtatt ttcgtggaac
    12901 tgatgtcgat ctcaggtaca tctacccaaa ttacaggata tggagtatcc gttgtgtatc
    12961 ctggtcgacg tatacccaca aagttgacca tagaagtcag ctcatcgatt ttataccatt
    13021 ttggcaaata ttctaccata tccccaccga taataaagta ataatctgta tccggattgt
    13081 tttgcgtcaa ttccttcata gtatcatagg tgtaactttt cccaccacga gctaattcaa
    13141 tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa ttccaacatg ttgagtcgat
    13201 gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg ctgataagaa ggcatcaaaa
    13261 atacgcggtc aagacctaaa ttccggccag cttgttcagc catcactaaa tgtgcaaggt
    13321 gaacgggatt gaatgttccg cccaagatcc ctacttgctt tttcttctct aagaattgag
    13381 gcatttcttc aggaaataat tgtgaacgaa caaatgtctt agcttgcgta ttcatcatgg
    13441 tcactcctta tattgctttt acttcttttg atagcctttg atacttttct tttgtggaag
    13501 gtttgtataa tacaataaca cgtccaatga tttggacgat ttcgcaatct atttcttttt
    13561 ctaatacttg agctgcttct tctgcaatct catctgtatt ttgaagtaac gatactttga
    13621 tcagttctct tttttctaaa gcttcttcaa tttgaacgat cattgctgaa ttgatcccac
    13681 cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt gctacgtaaa aaacgctttt
    13741 gttttcctct taaactcata attttccttc ttccttaaat caatgctttg cgtttcaata
    13801 catctacacc ctttggcgcc cagcccgcaa ttactactgg cgctgttaca gtgatccagc
    13861 ctagaccggc aaaaacgatg tctgtttttt ctttcacaga aaactcaaaa cgaacaagct
    13921 ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa taatccacct acatgttttt
    13981 gataaaattc gtctgctttt tccagtttcg ttcgatgaat atttacatca tttgacacat
    14041 aagcaataaa tgaagcacga ttgccgctga taaaatcaaa tcttgcaagt ccgcccaaga
    14101 aaagtgtttg cccttcattc agctgataaa ctttaggttt gatttctttt aacggtgcaa
    14161 tgatccgcaa atctttttta cctaagtagt gcgccatttg atggcgatgg ataattcccg
    14221 gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc gattttatcc aaggtcgttc
    14281 ctggaaactg cgaagttgtg attacatctt gtactcccgc tgtatttttg atgatttgat
    14341 tgataagcgt cgattttccg acatttgtta ctccgacgat atagacatcc cgtccatcgc
    14401 ggtattcttc gattttttct aatagttccg tcatctcatg agatttctta gcactagtta
    14461 ataatacatc tactggacga attcctgctt cgtaagcacg ttccttcatc cattgtgtta
    14521 atttagtttt tttcaatgat ttaggtaata tatccacttt gttcccaact aaaagtactg
    14581 gattgtcacc gacaaaacgg tgtagtcctg ggattagtga accattgaag tcaaaaatat
    14641 ccaccacatt gacgatcaat gcatcttttt gccctaattc attcagtaag cgcaaaaagt
    14701 cgtcatccgt caatgagaca tcttgggtct cattataatg gcgtaatctg aaacaacgct
    14761 gacaatagac ttccccggaa gctaaacctt tttccaaagc cgtttgcggc gtgtatccta
    14821 attcaccggg tttgtttgtt tgtataacgg caccacagcc gatacattgt aattcttctg
    14881 tcattcgatt ccacctcgcc agcccatatc agggtgtttt gctaatagat aggccataat
    14941 tcttttttcc caaaaacgat taaattgtgt cttccaacta tctgttgcga taatgggttt
    15001 tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt atatcagtca taatctgatc
    15061 gcctaccatt actatctcat catctgctaa atccaattgt ttctttgcta tgttgatccc
    15121 tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga tcaaattttt caatcgctcg
    15181 cgcgacacgt tttgaattat tgtttgaaac aacaacaaca gggattcctg catttttcat
    15241 ttctaaaatc caagtaagca actcttctgt tccatctgga ttattccatg caatcaacgt
    15301 attgtctaaa tcggtcaata ctgctttgat gcctagattc tttaattggg caggtgtaat
    15361 ctgatagatg gcttctacca tccatgttgg tttgtaattt gaaaacatgc tgtctcctca
    15421 tctgcaaaaa atgaaggagc acataaagta ctcctcaacc ccgtattata ctgcatatca
    15481 gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa aagcatttct ttacaaaatg
    15541 accaaaaata aagattgatc acagaaaaat ttagaaacaa aaaacaacta atattggcgg
    15601 aacctcttgt atcgtttttc cagtaattta tgctgatcta atcgaacaag ttccgtcaat
    15661 ctttcaatca acgctttttt cataatgtgt gcgactttat atcgtggcaa ctgctcgccg
    15721 ttgaacgttt caggaataac tcgatcaacg attcctaact cgcgtagttc tggcgcagta
    15781 attttcatca actcagctgc ttctgcggcg cgactaccgt ctttccacaa aatcgacgca
    15841 aatccttctg gagaaagcac agcataaatc gtttcttcca gcatccagac ttcatccgct
    15901 aaacctagag caagggcacc gccacttcca ccttcaccaa tgatgatggc gatgatcggt
    15961 acctttaaat cagacatttc gagcagattt ctggcaatag cctctccttc gccgcgctct
    16021 tctgctccta caccgcaata tgcacctgct gtattgatca aggtaatcac cggtctattg
    16081 aacttttccg cttgtttcat cagtcgtaaa gcttttcgat agccttcagg atggggagaa
    16141 ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt tttgaatacc gatcactgtt
    16201 accggtttgc catctaatcg agcgattcca ccaacaatcg cttcgtcatc tgcaaataaa
    16261 cgatcaccat ggcattcctc gaaagaatcg aagatctctt caaaaaaatc caagcttgtc
    16321 catcgttctt tagctcttgc taactgaacg acatcatgtg ctgtcttatc cacgatctat
    16381 ccatcctttc tgtgtatgca attcaagaag cgtatggatt ttctgtttca attccatgcg
    16441 gggaacaatc tgatcgacaa aaccatgaga taataagaat tcagcctttt ggaaatcttc
    16501 tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt ccagcaaaac cgatcaagct
    16561 ttggggttct gctagaataa tatcgccttc cattgcaaaa ctggcagtta ctcctccggt
    16621 cgtcgggtcc gttaaaacag ttagataaaa aagaccttca ttgctatgcc gtttgacagc
    16681 agcagagatt tttgccatct gcattagaga aaagattcct tcttgcatcc gtgcgccacc
    16741 tgaagctgtg aacaagacga ctggaagact ttcctttgtt gctcgttcga ataatctggt
    16801 gatcttttct ccgacaatcg ttcccatact tcccatgata aaattaggat ccatcactcc
    16861 aataatgaag ggaatcccct gaatggttgc tttaccagtg aggactgctt catgaagtcc
    16921 tgttttatct tgcatttttt taattttttc cgtatattcg ggaaatgcta gcggatcttt
    16981 ggttacaaga tccgtatccc attcttcaaa acttttttca tcaataatca aagctagacg
    17041 ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg catacttttt cttcaccgat
    17101 gtctttcgta taaaggatat gtttgcaatt tggacacttt gcccacatgt tatcaggaac
    17161 agatggcgag ttagcaggtt tgctctctct attaggattg atccgaatat atttcttttt
    17221 cttaaacaga gccatctatg cgcctcctat ctccgtttct ggtgtccaat tcggtaaaaa
    17281 ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg actgcaggat gactaatcaa
    17341 atccatctga aattctgcgt tcgtgatgat tccttctgtg ataaattcac ttaaggctcg
    17401 ctgcatcttc attaatgctt caaaacgcgt atttccatgg acgattattt ttgcaatcat
    17461 tgaatcataa tatggcggga tcgtatatcc cgggtaaact gcactgtcta ctcgcagtcc
    17521 catcccacct gctggaagca gtaagttttg gatcttccct ggagaaggag caaaatggaa
    17581 agcaggattt tctgcattaa tccggcattc gattgcgtgt ccttggaata ctacttcttc
    17641 ttgacacaca ttcaaaggct caccggctgc tatctccacc tgttttttta ctaaatcgat
    17701 tcctgtgacc atttctgtta ctggatgttc cacttggatt cgagtattca tttccatgaa
    17761 ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt ccggcatttt cataattgac
    17821 tgctttagct gctcgaacag cagcgtctcc tagtgcttct ctttttgttt gtgagatcac
    17881 tacagaagga gattcttcca gtactttttg attgttgcgt tgtaaagaac aatctcgctc
    17941 gcctaaatga atgacatgac caaatcgatc acctaagatc tgaacttcta tatggcgagc
    18001 aggataaatg attttttcca aatacatatc atcatttcca aatgccgctg ctgcttcttg
    18061 ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat tgaactttcc gaatgccttt
    18121 cccgccacca cctgcagctg ctttcagcat cactggataa ccaattctgt ctgctatttc
    18181 caatgcttct tctactgtag ataatacacc agtacttcct ggaatgactg ggacatttgc
    18241 ttcttgcatc aattgacgcg cattgatctt atttcccatt gcatcgatcg ttgcactttt
    18301 aggaccaata aatgtgatat tgcactcttc acacatggag gcaaatcggc tattttcaga
    18361 taaaaaacca aatcctggat gaattgcttc ggcttttgtc acgattgcag cgctcagtac
    18421 ttcctgaaca ttcagatatg aatcaacggc ttttgccggg ccaatgcaga ttgcttcatc
    18481 tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa tatatcgcta cggtttggat
    18541 ccctagttcg cggcatgcac gaatgatacg tacagcgatt tcaccgcggt tagctatcaa
    18601 tactttagaa aacatatttc acctatccaa tcataaaggt taattccgct tcggctactt
    18661 ttttaccgtc tactttagcg attcctttgc ctattccggc tgaagctttc actttcaata
    18721 tctcaacttc aaggtataag gtatctcccg gtgtaacttt cttacggaat tttgctttgt
    18781 ccaatccgcc gaaataagcc gtctttccct tgaattgttc aagagaaagt aatgcaactg
    18841 ctcctgcttg agccattgct tcaacaatca atacccctgg cataacaggt tcttctggaa
    18901 aatgtccttg aaaaaagggc tcattgatcg ttacattttt cttagcaacg atccgttctc
    18961 cttcaaccat ttcttccact cgatcaatca aaagcattgg ataacgatgt ggaatgattt
    19021 cttttatttc ttgtatgttc attgttttcc ctctttcctg ctttgcttat ttttgctgaa
    19081 tcctaaagag tggctgtcca tattcgacaa ctgactcgtt ttctacaagg atttctgtga
    19141 tcactccgtc ggcctcacta gttatctcat tcatcagttt catcgcttca ataatgcaga
    19201 taacttctcc tttggcaact tgatcaccta cttttttgaa agctggtttg tcgggcgctg
    19261 gttgcagata aacgattccc acgattggcg aaacaacctc gattccatca aatactgccg
    19321 attctttttc tttcattatt tctggagcag ttgttgcttg ttcaggtatg acattgactg
    19381 gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt catgcctcga cttgttttat
    19441 ttttattcat atacaattca aattgacctt cacgcaaatc gaattccgtt agcgaggatt
    19501 gatcaaattg actgactaat tctctgattt cattgatatc caaaattatt cctcccagcg
    19561 tttcatgcac agaaccgcat tatgtccgcc aaaccctaat gaattactca ttgcataagt
    19621 aaaacttgca ggtttgcttt cgtttttgac aactgtcaag tcaatctcag gatcttgttt
    19681 ttctacattg atcgtaggtg ggataaattg atgttctaat gccagcaaag ttgccaaggc
    19741 ttcgatcccg ccggctgctc ccaataaatg tccagtcatc gatttcgtgc tgctgacgta
    19801 agtatctctg aaattttcac ctaatgcgat ttggattgct tttgcttctg cctggtcatt
    19861 ggctggtgta cttgttccgt gagcattgat atatccgact tgttccggct gtacaccagc
    19921 ttcttccatc gcaagcttca ttgctttaga tgcaccagaa ccatctggag taggagctgt
    19981 catatggtaa gcgtcacagt ttgcaccgta tccaacgatt tctccataga ttttggcacc
    20041 gcgagcttgt gcatgttcta aagattcaag aactagaacg cctgctcctt cacccatcac
    20101 aaaaccattc cgattttcgt caaacggaat cgaaccacga ttaggatcag ttgattctga
    20161 gagtgctgtt aaagctgcaa atccagcaat ccccatctca caaatcgttg cttctgttcc
    20221 tccagcaaga atgacatcag aatagccatg tttgatgtta cggaatgctt ccccaattga
    20281 attcgttccg ctagcacaag ctgttacgat agctgtacaa ataccttttg cacctacacg
    20341 caaagcaata tttccagctg ccatgttggc aatcgccatt ggtacgaaca ttggagaaac
    20401 tcgttttgca cctttttcat gtagacgaat aacttggttt tcgattgttg gaagaccacc
    20461 gatcccagat ccgatgatga cgccaaaccg gtcttgattc attttttctt tatctaaacc
    20521 gctcatctcc attgcttcta aagcagcgta gattccatag atcgaaaaca tatccattcg
    20581 tttgctatct tttttaataa aatatttatc gtaagggaaa tctttgactt cacccgctaa
    20641 ggtaatccct gtttctgaag catcaaattt agtgatcggt gcgatgccat tcgtcccctc
    20701 ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata ggtgaagtga ctccatagcc
    20761 agtaattacc actcgattca tttgtttgct ctccttttct tatccgtgca tgaccaatcc
    20821 gccatcgaca ttgatgactt gtccggtgat atatggattt tgtgctaaga aaactgctgt
    20881 ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga atttgctttt ccgcttgttc
    20941 cttgactttg tctgctaaaa cttccgtcat atcagttgtg atgaatcctg gcgcaatggc
    21001 attacatgta atgcctctag ttgcagcttc tcgtgccaca gattttgtta atcctactac
    21061 gccagcttta ctagctgcat aatttgcttg accaatattt ccaatcaacc cagatacact
    21121 agagagatta atgatggccc cttctcgctg cttcatcatt tttttcaata cgtgctgcgt
    21181 catattgaag gttccaatca aattgatatc cagacatttt ttgaaatctt ctgcatccat
    21241 tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt actaacacat ggatcgatcc
    21301 aagcttttct tctgcttctt tgatcatttg tcccgctttc tcataatcag agatgtcacc
    21361 ggaaactcct acgcatttta caccgaatgc ttcgatttct tctatctttt cttttggaat
    21421 ctctccgcga ccattcaaaa tgatatttgc tccagctttt gcaaaagcta aggccatcgc
    21481 tttgccgatt cctcttgtac tacctgtgat aaatacattt tttcctttta catccataac
    21541 gttcctcctt atagtattgc tattgtttca tcaaatgtct gcttattctc aacacgcaga
    21601 actggtattg ttttatcgat ttttttcata aatccgctta atacttttcc ggggccgact
    21661 tcgatgactt gttcgatgcc gattgttttt aacttatgga tactctcata gaaacgaaca
    21721 ggttgcatga cttgctgttc aagtagtccc gcgattgttt ctttcttcat tatttccgtt
    21781 gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt gaatctgact taggtccttc
    21841 gccagttttt ttgctgccgg ttctaaaata gctgtatgaa aaggcccgct gacatttaga
    21901 gggatcattc ttttgaaccc tttttctttt aatagtaaaa cagcttcgtc tactgctttt
    21961 tcttcgccac caatcacgat ctgctgaggt gtattataat ttgcaggaga tacgatgccg
    22021 tacttgctag cttcatgaca gctttcctcg atcgtttcaa tcggcgcatt catcactgca
    22081 accattttcc cgcttccagc tggggcagct tctgtcatat aagcgcctct ttttgctact
    22141 aacgcaactg cttcagtgaa ggatagcgca ttactagcta ctaatgccga atattctcct
    22201 aaactcagtc ctaaagctgc atctgggatg attccatgct ccttcaataa gcgataatac
    22261 gcgatgctga ctgttagaat agctggctgt gtatattgcg tctgatccaa acgttcattt
    22321 tctgtaaagc aaagttcagc catatcgtag ccgagaatct cacttgcttc atcaaatgtc
    22381 tgctttacaa cggcttcttc atataaatct tttcccatac cttgatattg tgcaccttgg
    22441 ccactaaata agaatgctgt tttcatgttt ttctccaata tatccagaat atatgtttga
    22501 ttcttcctat tcaaaaaggc cgagacattc ctatttcagg aaatgtccca gcccccaacc
    22561 taattttaat gattatgcag tttgtttttc tacgtaagtc actaaatctt gaaccgtttt
    22621 gattccgtct tctgtttcga ttttcacgtc aaattcatct tcaatttcat tgatgatttg
    22681 gaataaatcc aagctgtcag cttctaagtc ttcttggatg tcagtagtca atttgatttc
    22741 ttcagtttct tttcctaatt cttctgcgat gatttcttga attttttcga ataccataat
    22801 aatatattcc tccgatattg tttgcttttt atttttataa tttaacagtc tacaactcca
    22861 tgagaatact tccccatgtt aaacctccgc catagcctgt aaatattact ttctgctgtt
    22921 ttcctaaggt gatctttcca ctagaaactg cttcatccaa taagataggg atgcttgcag
    22981 cagatgtatt cccatattta tccatattgg tcaggaactt ttcttgcggc atctttactt
    23041 ttcgggcaat tttctcaata attctgaggt ttgcctgatg caaaagcaga taatcaactg
    23101 gtttgtcttt catgacttct tggatattgt ttgcaacgtc tcgtacggca aaatcaaaaa
    23161 tatctctgcc agtcatttgc aaataatacg aaccttctga atcttctgaa tagaacggat
    23221 ttttattttg ctggtagcca gcggtcaatg agctacttct ggtaccgtca gctgctaatt
    23281 tttctttcag caattttttc tgtggattcg cttctaagag aatcccacct gctccatcgc
    23341 caaacaacac agcagtcgta cgatcagacc aatcgattag cttagatagt gtttcaccac
    23401 caatcaccag tcccttagtt gagccgcagc ggatcatttt ttcagccatg cttaacgcat
    23461 aaacaaatcc tgagcacgca gcactgatat caaaagcgat agcatgagtt gctcccaatt
    23521 tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc gggcgacatt gttgctacta
    23581 aaataaaatc caaatcttta gggtttagat ttttctgttt tatcaatttt tccgccacta
    23641 aaatgcataa atcagaagtc tcctgatttg ttacacatct tcgttcacga atacccgtcc
    23701 ttgacgaaat ccattcatca gaggtatcca tcatcttgga aagatcatta ttagtaataa
    23761 tcttttcagg aaggacgctg gctgttgcag taatcattcc aaattgttcc attaaatatc
    23821 ctcacttata gtcttgcaag aagtcgtgca agtttttcag tgcatccagc aaggcatgct
    23881 gttcctccgt agccattccg tctaagatgt tcttgaccat ttcacgatga aaatgctgat
    23941 ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa ctttacaacg cggcggtcat
    24001 cttcactgcg gatacgttcg acatagcctt tttttactaa cttgttaata gcagtggtca
    24061 aggtcccaac agtaattgat agttctttgg ctacttctga agttgttttt ttcttgtaca
    24121 tcccgattgc ctcgatcgtg tgcatctctg tgattgacag atctttgaat tgagattttt
    24181 tcagctcaga ctcttcgatt gtcaaaatat cattgaagac actaacaaga taatcattta
    24241 ctgtttttaa atctggttcc atgttccacc gtccactaat tagtttgatt atcaaatctt
    24301 ttgatgttca aactatatct taactttttt caaaatgcaa ccttaaaaga tcattttttt
    24361 actatatgag ctttttttaa gattttactc atttaaaaca actgataaat cagcatttat
    24421 aatttctttt attagaaaaa tcatctatct cacatatttt gattatcaaa gtattttctg
    24481 tgaacagaac tatagaattc cctaaaactt gtccattatt tcaaaatttg ttatagtctt
    24541 tttattcaaa gcgtaaaagg agatcctatg ttaaaagaaa aaatgaaaac tctccccatg
    24601 ctgccgggtg tctatcttat gaaagaccga gatggtaagg tcatctatgt tggtaaagca
    24661 aaacggctca aaaatagagt aagcagctat tttcatcaga ataaacagca ttcaaaaaaa
    24721 gtattacgta tgattcatca tataacagat tttgatttcg tcgtagtaga cacggaatta
    24781 gatgctttat tgctcgagtg tcaattgatc caacattacc gtccttttta taaccgacaa
    24841 atgaattatt tcagtaatta taattatgta catattacca ataagggatt tgtattaaca
    24901 gatactccta cggctcgaac atacgggcct tttcgtctct ataaaaaaat gccgtctatt
    24961 ttgcgtataa tggaagaaac ttatcaaatg ccttggttgt ctgaaattag tttgttagct
    25021 ttgcgagtcc agcttcctga cctacaggaa atgacttttg aacagaaaaa aaaggaactc
    25081 caagggctgt ttcaaggccg aaataaaaag ctactgactt acttgaaaaa aagacaacaa
    25141 catttcatct atcagttgaa tttcgaaaaa gccggtatgc ttcaaaaaga tatcgaatta
    25201 gttacttatt ttattagacg gatccaggaa caaaagcagt ttttaagaac accatcgctc
    25261 accttcagca tgccattagc agcagatgag agtcagaaaa agcactacct cgtttgttat
    25321 ggtcaacttg cagaaacaat gattacctct ggtgacgttt ctcctgactt ctattatgaa
    25381 aagaaagaag ctcatttatc tttgaaacgt caattgtcaa aagaagaaat cgatcctgta
    25441 caaatcttga tcagttaccg caaaaaatta gaaaaagaac agtttgaaat tgaactgtta
    25501 aacaaaaaag aagctgaaaa gcaactaaat tagttgcttc tcggcttctt ttaggcatct
    25561 tcaacttcaa atgtcaatta tcctaaaatt tattggatta agtcatagat ttccatcgct
    25621 acgatatcga tattatcaaa ttcgtattgc tgatgagtat ctgtttcagt taattcaaat
    25681 gtatcggtcg ctttatcata agttactgta cacttctcta cgccttcttt ttcaaaacgg
    25741 cgaacttgca gttcattatc tgctgactcg accatagcct ccagtcgttt tatgattgcg
    25801 actaattgtg aatgtgtcat cggaggtcct ccttttctta tttctgttat attgtatcaa
    25861 aagcatagcc tacttgcatt gattttctct aaaaaaactc gttttttatg attttttttc
    25921 tggtattttt ccttcaggcc accaaagttt gatcaaagct tgggttccgt cattctcaaa
    25981 acctttatct gccaactctt catatagttt caatgcttgg gtagttgctg gcaatacaag
    26041 atccattttt tctgcttctt ctaatgcaat ctttaaatct ttgataaaat gtttgacaaa
    26101 aaaaccaggt gtgtaatctt cttttaaaat acgaggagaa taattgctta aagaccagtt
    26161 agctgcactt ccacctgaaa gcgtctcaat cactttcttt aaatcaagtc cgtttttttg
    26221 tgcatagaca agcatttccg tcattcctgt catcgtacct gcaatcatga tctgattagc
    26281 catttttgta tgctgacctt tcccagcaga accatgcaat gtaaatgtcg taccaaattc
    26341 tttgaataaa ggcagtactt gatcataaac ggcttcttct ccaccgacca tgatcgtcag
    26401 tgtaccattc tttgctccta agtcaccacc ggataccggt gcatctaacg catctgcgcc
    26461 tttttctttt gctgtttttg caattttttc tgccaggctt ggtgtacttg tagtcaaatc
    26521 aactaaaata tgtcctgaga tatctgcaga aaaaatcccc gactgtccat agtagatttc
    26581 ttctacatct ttggggtaac ctaccattgt aaagagaata ttactttgtt ctgctaccgc
    26641 ttttggtgta tctgcccaga tagctccttc tgttactaaa ggatcagctt ttgcttttgt
    26701 ccgattatag acagctactt cgtgtcctgc ttctagtaga tggcgtgcga cagcacttcc
    26761 catgacgcct gttccgataa aaccaagttt cattttttcg acctcctaaa aatcaaaaat
    26821 ccttgcttct atgctagtat acgctagaaa caaggatttt ttcataaaaa atgtttgaat
    26881 tttatctttt aaatgaattt aattttattt tgattcgttc aatcgagtct tcttcttctt
    26941 ttcttcgcat ctcttcttca tgataaacaa ccatgtcttg ataaaattcg atcatagctt
    27001 cgccgaaatg tgtagatgaa atatcataaa gtttagcttc taaaactttt ggatctttag
    27061 gaacttcact ggaaatataa tcaataagtg ctggtgcaaa gtcttcgtcg gtttcaaaag
    27121 ttttccctaa tgaaggatga tcgaacaatc ggttcaaata agcatttcct tccacgacac
    27181 aaggtgttcc ggctgccatc gcttctgtat aagtaagccc ttgtgtttct gaagtagaag
    27241 cactgacaaa ataatctgcc gctttataat aaagtgctac atcattgttg tccacttctc
    27301 ctgtgaactg cacaaattct tctaactgca gttctgagat caattcctct aactcttcta
    27361 cataaggtcc ttttcctacg ataactaatc tggcgttagg ataagcggag atgacctgag
    27421 gaaacccatt aatcaaggct tggatatttt tctcataaga aatcctgctt aaagaaagaa
    27481 tcatcaaatg gttttcctga agacctagtg actcccttaa tttgctgata tcctgctgag
    27541 tgatatcaga acgtttgaat ttttcaatgt cgataccagt aggaatcacg cgaagcggtg
    27601 ctattacacc atagctgcgt aatgtatcaa taacacgttc acttggacaa actacacctg
    27661 tcgtatgatt tgcaaataat ctagacaagt attttacatg ggattgcctg atcacttttc
    27721 ctttaccgat ataatgaagg tagtcttcat acatcgtatg gtaagtatgg atcagaggta
    27781 ttttcaactt cttagctacc atcttcccaa gtatccctgc tccgaattct gtatgggtat
    27841 gaataagatc tagttctagt tctttggcaa ccaaataagc ataccacatg cctctaacaa
    27901 caactcttcg atccttgaaa gaaataaatg gtacacttgg cattcgaatc acatcttttt
    27961 ccaacttatc cgcattagga tcggtcgttg taaaaatata gacttcatgc ccatgtcttt
    28021 ctaattcttg ttttaatgtt ttgatcgatg tagcaactcc gctgacttgc ggaaagtagg
    28081 tatcggtaaa aaagccgatt ttcatgtttt tcgcctccaa actagtcctt gacctgattt
    28141 acttttttta atttgctaga gactttttca ttcagtacac tttcgtatac atttttaagt
    28201 tcttcaccga ttttattgat acttcgctct tttgctgttt gataaccggc ttgtgtcgta
    28261 ctcggtagtt cttgattggt aatctgttgg atcagtcgga taaattcttc gtttgtcttc
    28321 cccatatagc agttcttgct atcttctaac cagccattat acactggaat atctcgaaca
    28381 agtacgtttt gtttgcttgc taaagcttct aaaacaacga tcccttctgt ctcttcataa
    28441 gaagggaaaa agaatagatc tgcacctgaa tacgcacctt ctatgatctc tccacgaatg
    28501 taaccaggaa acaggacatt ttcaggatga tcttctttta caattttccg gatgttccga
    28561 ggaatcgagt acatgggaac atgaccaaac caaataaatg tgtattcggg catcttctta
    28621 gcaatttcta cgaaatcaat gattccttta cgttcgaaaa acaaaccgac acaaatgatt
    28681 actttttgat ccggagacag tttgaaatat tctctgaact tttgttcttt cattggatca
    28741 gggtgatatt tctctaagtc gatcccattg gaaatagctt gaatcggcac acggatacca
    28801 tagctttcca acaactgttt tgaataaggt gttggcgtga tcagatagtc cgctttttgg
    28861 tacaatccta ccagatattt ttttacgata ggagaaagct ggttcgatcc gataaaggaa
    28921 tttcggaaat cttcctctgt agaatgcgca tgatagacaa ctttttttcc ttctcttctg
    28981 gctttattga ccatattatg actattgatt ccgtatgtat tgatgtgcag gatgtcataa
    29041 tcttcttttt catctagtgt ataagagata ccgacttccg tcagagcacg tttttgatga
    29101 tcaagcgcac gcccgattcc agattttgca agcatctttt cactttcaaa atataataat
    29161 accttcacct tacgtccccc ttcacttata tagtataaca tagcctacaa actgtcactc
    29221 aaacttaagc cctattttt
//
LOCUS       DACGDM010000025        27870 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.025, whole genome shotgun sequence.
ACCESSION   DACGDM010000025 DACGDM010000000
VERSION     DACGDM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.025"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(419..1363)
                     /locus_tag="IXR05_001233"
     CDS             complement(419..1363)
                     /locus_tag="IXR05_001233"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4259770.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1659..2603)
                     /locus_tag="IXR05_001234"
     CDS             complement(1659..2603)
                     /locus_tag="IXR05_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4259771.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2824..4038
                     /locus_tag="IXR05_001235"
     CDS             2824..4038
                     /locus_tag="IXR05_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4259772.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4060..6075
                     /locus_tag="IXR05_001236"
     CDS             4060..6075
                     /locus_tag="IXR05_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAQ4259773.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6158..7531)
                     /locus_tag="IXR05_001237"
     CDS             complement(6158..7531)
                     /locus_tag="IXR05_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4259774.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7557..7841)
                     /locus_tag="IXR05_001238"
     CDS             complement(7557..7841)
                     /locus_tag="IXR05_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4259775.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7843..9858)
                     /locus_tag="IXR05_001239"
     CDS             complement(7843..9858)
                     /locus_tag="IXR05_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4259776.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10037..10342)
                     /locus_tag="IXR05_001240"
     CDS             complement(10037..10342)
                     /locus_tag="IXR05_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAQ4259777.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10431..11462)
                     /locus_tag="IXR05_001241"
     CDS             complement(10431..11462)
                     /locus_tag="IXR05_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAQ4259778.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11669..12544
                     /locus_tag="IXR05_001242"
     CDS             11669..12544
                     /locus_tag="IXR05_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4259779.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12696..13538)
                     /locus_tag="IXR05_001243"
     CDS             complement(12696..13538)
                     /locus_tag="IXR05_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4259780.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13630..15507)
                     /locus_tag="IXR05_001244"
     CDS             complement(13630..15507)
                     /locus_tag="IXR05_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4259781.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15504..16925)
                     /locus_tag="IXR05_001245"
     CDS             complement(15504..16925)
                     /locus_tag="IXR05_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4259782.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16928..20317)
                     /locus_tag="IXR05_001246"
     CDS             complement(16928..20317)
                     /locus_tag="IXR05_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAQ4259783.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20574..21965
                     /locus_tag="IXR05_001247"
     CDS             20574..21965
                     /locus_tag="IXR05_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4259784.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22038..22685)
                     /locus_tag="IXR05_001248"
     CDS             complement(22038..22685)
                     /locus_tag="IXR05_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4259785.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22693..23379)
                     /locus_tag="IXR05_001249"
     CDS             complement(22693..23379)
                     /locus_tag="IXR05_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259786.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23385..24458)
                     /locus_tag="IXR05_001250"
     CDS             complement(23385..24458)
                     /locus_tag="IXR05_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4259787.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24680..25354
                     /locus_tag="IXR05_001251"
     CDS             24680..25354
                     /locus_tag="IXR05_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4259788.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25359..26699
                     /locus_tag="IXR05_001252"
     CDS             25359..26699
                     /locus_tag="IXR05_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4259789.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26848..27834)
                     /locus_tag="IXR05_001253"
     CDS             complement(26848..27834)
                     /locus_tag="IXR05_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAQ4259790.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8126 a         5267 c         5052 g         9425 t
ORIGIN      
        1 tgataaacct ctctcgaacg gttttttatc aaaaatcgtc atttttccat caaaatctgc
       61 ttatgcaaaa ttataaaaaa attttgcagt ttttcttact ttttttgtcg tttaattgaa
      121 tgataaaaac cagtttcttt attcagttaa tcaaatatga acgaattaga tatgaatcat
      181 tgtatttgcc gttgcggaag gattttttaa ttaaccacag ataaacattg ataacgattc
      241 gcttattgta atcaacagat taaatttcat atgttcatat gtacggatac attttcggac
      301 cgattaattt taaccattct gtttatttgc ttacctatta gatatcaata aaaaactgct
      361 taacagctat ttcagctgtt aagcagtttt aggattttta gttcatattc attgtttctt
      421 ataatacagt gttcaatact tctcttaaag cacttgttga tttgctgaac attgcttttt
      481 cttcttcgtt gattgataat tcaacaactt cacgaacacc attttcgtca acgattgatg
      541 gcacacctgt aaagatatct ttttcgtcgt attcaccagt taaataagca gatacaggca
      601 atacagcttg ttcgttattc aagatagctt ttacgatacg tgcagtactc ataccaatac
      661 catagtaagt tgctttttta cgatcaatga tctcataagc agcattacgg actttatcag
      721 caatcacatc taattcatct tgggcaatac gatggtcttt ttctacaatt tcaaacactg
      781 gtttaccacc gacagttgta tgtgaccatg cagcaacttc tgaatcacca tgttcaccta
      841 agatatagcc gtggacgctg cgtgggtcaa cttttaattt caatgcgatt tctttacgga
      901 aacgagttgt atccaatgtt gttccagtac cgataacacg tgatgttggc agaccagatt
      961 cgttccaagc gatatatgtc aaaatatcta ctgggtttga agcaacaacg ataataccgt
     1021 cgaatcctga tcccatgatt tcttttacga tttggcgcat gattgacgca tttgttttaa
     1081 ctaaatctaa acgagattga ccaggttttt ggttgatacc agctgtgata acaacgatat
     1141 cagcatcttt acattcttca tagccacctg accatacagc cacattttca tcgccccaag
     1201 ccataccatc taaaaggtcc aatgcttccc cttctgcttt ttcttgattc acatcgatca
     1261 atactaattc attagagatt ccttggttga tcattgcata agcgatactt gttccaacaa
     1321 aacctgtacc gacgattact actttacgac ttgttttttt catgaataaa cagctccttt
     1381 tcataactat ttgttacttt catgaaaagt atagtcttgt ttattcattt tatcaacatg
     1441 ttaattataa tagttgttat tataattttt gatggaaacg aattcctgaa tacgcataac
     1501 agataaatga caaatgttta cacctatatc ccctgataat acaaccaaaa gtttagaact
     1561 gaaaataaat ccaaaaaaat tcgctgcaac gatataataa gacagcaatc gcacctaaaa
     1621 caattttcct tcatatgctt tagtgaaaga ttttcttctt aatgtttatt tctccattca
     1681 ttgggagtac atgttgaata cttcttgaat aatttgaata aagaagtcgt ttgtttatat
     1741 ccgatacgat tagcgatttc ttccaacgaa aaactcgttt cttgaatcag ttccaacgca
     1801 aagtcgaatt ttttctttag aaccagttct tgaaaggaag catcaaaata cattttcaat
     1861 ttattactaa gatagaccgg attgtagcca aaatgagctg ctgtttcttt taacgtacaa
     1921 gaagtaaaat gcttatcgat ataatctaat actctaagca tctcattttc tgcgcatcca
     1981 tctgctgatg aaaagctttg ttgttctaat aaatgagtca attcgatcag taatagtgat
     2041 gtatagagat ttaacgaacg gatcttatga ctgtatgtat caaaataaat caacagcata
     2101 ttttcaatca aatgcgtcaa acgacttgtt tttccgccgc gaaaatgaat gaattgtgta
     2161 tgttcccctt tttcttttga tgcatttatc aaaaaagaag aaagtagatt atttgtgctt
     2221 gccaaatgat tcaatatctc tgtagataag gtttcttctt ttaataagat gttgattaaa
     2281 atatcctctt gccctgtgta ttcgattctt tgagtagctt ctttatcaat gatcaccacg
     2341 tcactttctt ccatctctat cctttctcca ttaataattt gtaaacatgt accgctatac
     2401 atataattga tttcaacaaa atcatgtgta tgctcgggaa cttccgcata tcgacggtgt
     2461 ttactgatat gaatatttcc ctgttgaaat agatcccctc ggtggatttt tggcggtgtc
     2521 tgaagatggt aagctaagtt taaatcattg atattcattc cttgttcacg ctgcagagtt
     2581 tcgattgatt cttcgttacg caaaaaaaat gtctaattca gctagttcca attgactccc
     2641 tcctttttgt aagcggtttc tttcgcttat tagttcacgc tgtactgcta ttatatgcaa
     2701 agctattttt ggtttcataa agactttcta tggttgggac atgaacttcc tgtgattccg
     2761 ctattgagag aataaccact tcatactata tttttgataa gcgcttacaa aaatgaaagg
     2821 aacatgctta tgaataaaaa gatgatgaaa ttttctctgc tgtcagtctc tcttattttg
     2881 acttctgctg gtgcagtcac gtctgcaatt cccagtatgt cagctactta tgccacgcgt
     2941 tctttatctg ctgttgaatt attaacgact gctccctctt ttatggtcac tatttttgtt
     3001 ttgattagta gttttattgc taggaaaatc ggacaaaaac aaactgtgat catcggatta
     3061 gtgattgcat cgatttgtgg tatcctcccc ctcttctcac aaagttacag tattgtctta
     3121 gcttcaagag ctggactagg tattggcttt ggattgatca attctttggc agtcagcatg
     3181 attgctgcct tttatcacgg agatgaacga gcctctatga ttggttttca aagtgcattt
     3241 caaggatttg gtgcagcttt aatgacattt gttgcaggac agctagtaca gttcggttgg
     3301 caatatacct ttttagtcta cgccatcagc ttacctattc ttgtcttgtt tgttttgttt
     3361 gttcctacac ctgaaacaac tgaacttcaa tcgcatggca cagccccaac aagacaagta
     3421 atcaaaacga atcctaaaat gattagttat ggtatttttc tcttgctggt catcgtggta
     3481 tataatgctg tatcgattaa attagccaca gtcctgacga cttattctct aggaaacgaa
     3541 actaatgcag cgaatatctt aacaatcatg caattggcaa gtatggctgc cggagtttgt
     3601 tttggctggc ttcagacaaa agcacatcgc tatatgctta cactttcttt actactgatg
     3661 ggaatcggct ttgtattgat tgccactgtg ataaacctgt atgtgattgg gtttggtgcg
     3721 atcctaacag gaatttcttt ttcgttattc attccttact tattcaacca agtaagtatc
     3781 caagcgccca agtacgcgga gagtttcaat acttcaatct tattggttgg cgctaattta
     3841 ggtactttca ttgcaccata tggtttgctc tttctctctt ttgcttctct tgggagtaaa
     3901 acacttgctg ttttcgtcaa tggcagtatc ttgctgttga ttagcgcgct tattagcctt
     3961 ctagtagtac acaggacgaa tagaaagaca gtgataagag tagatgaaga aataaaagaa
     4021 caattgacaa caaaataaat ttgatggagg tcgtgtaaaa tgacaaatga aaaacataaa
     4081 gatagatggc tttggtatcc tggagacttt gagatccgcc atggactgct acaaaatttc
     4141 caacgggaag aacgaggttt tgactggcca gcgtactggt acatggatga ttgccatcgg
     4201 aacgtcaagt ttaagagata ttactttctt gatcaacctt ccatgtttaa agtgacgatc
     4261 caaggagttg ggtatgtaga aattaatgga caaaaacatc catgtggaaa atggctgact
     4321 tgtccagctg gtaaagcaaa aattcgtatc tttgtaggac atacatcagg gctaccagcg
     4381 atgtttatcg agggagacga agtaaaatca gatattggct ggacagcaag taattttatt
     4441 gaagaatatc cagctggctg gagtccgctt tatgtcgata tcgcaaaaga tccaaatcaa
     4501 atctattatc aaaaagaatg cgtccatcca gtcactgaaa cggagattgg cggaggaatc
     4561 ttattcgatt ttgggcgagc agtgaatggc tgtgtagaac taatatctct ggatgaccat
     4621 atcgaatcta tcactctatg ttatggagag tccgatgtag aagctatgga tatcgattat
     4681 tgctactata agcaaatagg aatgacaaga aaaatgaaag ctcgtaaacg cgcttttcgc
     4741 tatttgttta taccagaggt ttctactgga atggttcaac ttcaagtttt tcatgaattt
     4801 ttatctcttt cgaaacaagc tgctttttca agcgattctt ctttactgaa tcagatctgg
     4861 tcagtatcag aagaagcctt caagttatgt agtgatttgt tttttatcga cggtatcaaa
     4921 cgagatcgct ggatttggtc tggagatgcg tatcaatcat tcatgatcaa tcaatatctt
     4981 ttttttgacg aggaaatcaa taaacgaacg atattagcat taagaggaca aaatgaaatc
     5041 aagcagcata tgaatactat cgttgactat tcgatcttgt ggttgattgg tatcgaaaac
     5101 cactatatga tgacgaaaga ctatgaattt ttacgcatcg tctaccctaa gatgcaatca
     5161 ttaatgagat acttgatgga gcaaacgaat gaattagggt ttatttatgg gagagcaaaa
     5221 gattggatat ttattgattg gtctgaaatg gataaagaag gaacgcttgc tgcagaacaa
     5281 gtcttattac tgaaagccta tcattccatg atcacttgcg gagatatctt agctgaaaca
     5341 tatggagaga acgaaaatta tcatactcat ctctatcaag aaaaatatca actattgaaa
     5401 caaaacctat ttgactactt ttgggatgaa gaacttggcg cttttatcga ttgctatgaa
     5461 tctgggagaa gaaatgtgac gcgtcatgcg aatattttcg ctgttttatt cgattttgct
     5521 aacaaagacc aacagcaatc gatcttaaag aatgtcttat tgaatgacac tatcacacag
     5581 attactactc catatttcaa attctatgaa caagatgctt tatgcaaact cggacagacg
     5641 aatatcgtct accaaacgat tcttgattat tggggaggga tgttatctca tgatgcggta
     5701 actttctggg aagaatacga ccctactcaa acaggaaatg aaaagtacag tatgtatgga
     5761 gatccttatg gaaaaagctt atgccatgca tggggagcaa gcccaatcta tcttttagga
     5821 cgctatttta tcggtttgta tccaacaaag ccaggttatg aagaatttat gatacaacct
     5881 aatctagatt catttgaaac actgaattgt acgctaccta tcaaagatgg aaagatttcg
     5941 cttgaaaaaa caaaagataa gatcgtgatt acttctgata gaacaggcgg aacagtgaaa
     6001 atgaatggta aaagttatcc tcttctagca aaacagccac ttgtcttaac aagctattca
     6061 aaaataaatg cataaaacaa aaaactgctt gcgacatatc agaagacttt aaatcttctt
     6121 ctgatattgt ccaagcaatt tttattttga agtttgctta attctgttct ttagaaacaa
     6181 tgtttgttct ttttccggca aaaagaaagc tagataatac gacaagtaaa aagaaagcga
     6241 tgattccaac tgtcaaggct atttgaccgt attctcctag tttcccaagt acaagtcctg
     6301 gtactagata atcagtatcg gcaaatgtag aagaagcgat tttaagatct cctaatactg
     6361 gaaggataaa taatggcagc caactaatca ataagctatt gaaagcagaa cctaataccg
     6421 cccctcttct accgccagtc gagttgccga agacaccaga agcagctccg cagaagaaat
     6481 gtcctactac cccaggaatg ataactgtag tttgcaagcc tatcatagca aacatggata
     6541 gtgttcctac aaagaagcta acaaaaaagc caattaatac agcattaggt gcatatggaa
     6601 aaacgatagg aacatctaat gctggtttag aatcgggtac gagtttttta gcaatccctt
     6661 ggaatgctgg aacgatttct gccaacacca ttcgaacccc ttgaaggacg ataacaaacc
     6721 cagctgtgaa tgttccagct tggatcagtg caaagattac agcgttgtct ccattgctta
     6781 gttctctttc aacaaatcca ggaccagcta acaaagcaag tgcgacatat acgatcgaca
     6841 tcaagagcat gatcgataca gtagaatctc gcaaaaagct gaaactttta ggaatcttta
     6901 tgtcctctgt agaacggtct ttgtttccaa aaaactttcc gatccatcca ctagaagcat
     6961 aaccgatatt tccggtatgc cctaacgcaa cttgattgtt tccagtgatg ttcttcataa
     7021 acggttgaca aagagcaggc gtaatagtta atagtgttcc ttcgaagacc ccgcctaata
     7081 agatcatcca caaatttgca gtaaaccccg cgcttactaa aatgactgct gttagacaag
     7141 aaacataaag cattgcttga cctgtaagaa aaatgaattt atatcttgtg aatctagcaa
     7201 gtaaaatatt cacgatcatc cctactagca tgatcaaagc agtaggtgta ccgtattgtt
     7261 gcaaagcaat cgccactact gcttcattgc taggaactac tccttgagta tgcagagctg
     7321 tttggaacat cgaagcaaaa ggggttagtg aattactgat taaaccagca ccgccgatca
     7381 gtactaggaa tccgacaaat gttttgatag ttccttggat cacttctgaa aatttcttct
     7441 tctgaagaac gagaccaagc agtgcaatca aagaaacgag gatggagggc tgactgacga
     7501 ttgacacaaa caaattcaac aatttatcca ttgatagttc ctcccttgaa tcatttttat
     7561 tcttttgaca agatcttcgt tactttttct tttacttctt cgctgtcaat gatcgattgc
     7621 aaaggtacga gcttttcatc aggtatagaa gttagcgtat ctttcaaaga atgctcaatg
     7681 aagaaataat cagccatatc gctagataca cttccaacat ccgtatgact tacttcaaac
     7741 tcgtccacat ctgctccaag atctgcaagt gcttgtttga tgttcatctc taccataaaa
     7801 cttgttccta atccactttg acatactgca aaaattttca tatcattcgt ctccttttct
     7861 tatgatcgct aatatttctt cttttgttga tgcgtgtaat aaatcttgaa gattttgttt
     7921 attagaaagt agctttgtta aatttgccaa agcccgaaga tgtgcctcat tatcgatagc
     7981 agctaaacag atgaacaaac taatgggatg ggctggatta tcaagcagat ccacaggttg
     8041 ttgaagtttc agcaaagaca tccctacttc gtttacgcca tcttctggac gagcatgagg
     8101 taatgcgatg tgatcgccaa tatggataaa cgcaccatac tgctccacgc gctcgatcat
     8161 agctttgata taactttctt ctattttatt ttctgataat agcggctgtg cggcaaatgt
     8221 gattgcttct tgccagtttt ttggttgatc cgataattgg atcatttctt ctgttaataa
     8281 ttcagatagc ataggacgtt gatcctcctt cttttctaaa agtttgttca ttttacgatt
     8341 taatacttga tagagctttt cttcgtctac gccttctttt aattcgatat aaggcagtag
     8401 cgccgacaac aattcttggg cagaaggcat tgaaaatcct ggtatcagcc aatctctttg
     8461 tacttgattg atcagctgat ttttttccaa gtcagtcatg attggatgca gaacatagag
     8521 agactttttc ttatcagtaa gtgtgagagg tacagtagaa aaaataatat cgtaagaagt
     8581 ttcgtcaacc tcgtgtaagc ggtcagctga attagtctct gtaaaaaaga tcatcgggaa
     8641 taattgctga agttcacttt ttaagatcaa tgaagagcta atgccacttg gacagacgat
     8701 cacggctctt atttttctat ttctttcttc tgcgtccgct tttctgatct ctccgccaaa
     8761 tagtatagtg aaaaaaccaa tctcttcttc agggatgctc ttccctattc gtctttctaa
     8821 cggaagtaat gcttttcttg tcatttcgta gatggaagca tattgatgct taatttgatc
     8881 gatcatcaca ttaggtaaat aaaaagaata ggaaatacga aaataggcag ggaccaagtg
     8941 ataaaagaca ttcatcaata attcacgaaa cgaagcaaat tctacggcca tcaggaattc
     9001 catgcgatgg atgacttctg aagaacattc cagcaaaaaa tcaagtgcag gctcctggac
     9061 atctccttca acgatcgatg ctaagcaaag agagaaaaat ataatctccg aattttgatg
     9121 ttcggaatag ccaaggccag tcaatacttg tcgactaatg tcagtgactg caagagaagc
     9181 caacagttca gcatctttta ccagttccat ggatgttttt ccaattcgaa tggttgtcaa
     9241 actcaaataa taagctaatt catccattcg atttggtgcg aatcgaagat ctgatagtga
     9301 aatcgtttta tctagcaaat ctctaacttt ggcgtaataa tcaatggaaa gggttgcggt
     9361 taaatacgtg agcccaaatc ttccagcaag tgactgcatc aaacgagcag tgcgattttt
     9421 tgcttctctt cttaatattg cttctgaccc tagcagccta aaaccagttt tcctagtata
     9481 cgacagctga caatcttcca cttctaattc atttcttatc tttttgatat ctgacaggac
     9541 tgtcccttta gaaacctgaa gaaaatcttg aaaatgaaaa acagaaacag acgttgcagt
     9601 cgaataaacc atcaaataaa gaagatctct tcgctcttgt tcggtataca cagcttcaaa
     9661 tcgagtaata tccaaaaatt tttctgccca gtcgattgct cggaatttct ttatacggat
     9721 acgggtatca tccacatatt cggcaaaagg agttaattgt ttgatcgcct cgcttgtatt
     9781 tacttcgatg atctctgctg ctttttctag actgatttct cttggtgttt tcaggagata
     9841 actaattttg tagttcacag cgctgttcac ctcctactta tattctagta tggtagcgct
     9901 tttaaatcga ggggtgtttg gtacaactta cagttggatt ttttttacga ctgtaccgaa
     9961 cgatttctat cgaatggata cagaaaaaaa gcaggtgacc aaatgtctcc tgcttttatg
    10021 aattgatttc gtccgatcaa tgatgatcat gtttattttt tgaggtcagt tcttcaaatt
    10081 tttctttgac atcttcaacc gctttttcga tatctttttc aaagtgattg ggctcattag
    10141 gctttgtttc ctcttctaca gaatttgaac cagataaagc tgtttcttta ttttctgttt
    10201 caccagagtt tgtgccagct aatgattctt ctttgtcttc tgtttcacca gaattagttc
    10261 ctgctaaagc cacttcttct tctgttttag gggccattga acctcttaat cgtttgtgtt
    10321 tttcaccgtc ataatttgtc atgttggttc ctcctagtag ttctatactt tttcatcgta
    10381 caataagaca gtttatgcgt caaaaaacaa acccgattct tacaaatatg tcatattttt
    10441 ccttctgatt cttgaatgct tttgattcct tcttccaaaa ttttcatttg taagattgtt
    10501 tcttcatctt tgatgacttt ttctgcgcca ttaactaatg tctcgtaaat cccttcgtag
    10561 acacggctgt aatcaccaac ctcggaaatt actttttctt catgataact cccttgttca
    10621 tctatatagg tcaatacacc ataatgttcg ggcaaatcga taccaaagtc ttcatgatca
    10681 ggcatgtaaa acattttcag atgttcttct tgtcgatctt ttgtttgttt cacgaacatc
    10741 cctttttttc cgtaaacgac gaaacttgga cgttctttga tgcggaaata actggatttt
    10801 atcgaaattt tcatatttcc atagaaaaaa tccagatcga agtaatcatt cattcgtcct
    10861 ttccctaaaa gttgacgtac atcatagctg atatcatctg gttcgccgaa ataagaaaga
    10921 acttgatcta ctgtatgaca agcatgtcca tataaatagc tgttcgcagt agaaaattca
    10981 tgcgtatttt ctggtacttc cggtctgaaa taatcataat gcatttctac ttctaaaata
    11041 tcccctaatt ttccgctttc gattactttt tggactgtca agaagtcaga atcgaaccgt
    11101 ctgttttggt aacattggat aaatagacct ttttcttttg ctaatgcaaa taactcttct
    11161 gcttcctttg acgtttctgc aaaaggtttc tctactagta cattcttacc atgttcgagt
    11221 gccatttttc catattcata atgaaattga ctaggtgtag tgatgacaac taattggatc
    11281 tcaggatcat cccaaagatc agacagctga tcagtatatt cgatgtcttc gaatgttttc
    11341 cacactggtt cagatgggga aaaaattttt ttgatattga ttttgttcgt aagttttctt
    11401 gaaaaaggca aatgatagcg atttgtactc tttccattgc caagataagc gattgtaagc
    11461 atgagtggtg cctcctttta ttgatgtttt cagtatatcc tagaaaagcg cagaaagtat
    11521 ttataatagc tattctggta aaaaagttca gaaaaacact tgttatcatt cggtttggtg
    11581 aaattaatgt tcaaagtaag gataaaaatc aaaaagatag tagcggaacc aagtgtttat
    11641 cagtaagata gaatttggag gtcagatcat gcttattgaa gaaaaactaa caaaacaaga
    11701 gttgtttacc acgacagaga aacggattgt cgattacatc cgtaggaata tcgaagctgc
    11761 agtctacatg acgattgaag aattagcaaa agctacgtat acttcccatt cagctatcat
    11821 tcgtttatgc aaaaaaatgg gattcagcgg atttaaagaa ttccgtttcg agctggggcg
    11881 ggaagttcat caattgattg ctcagttcaa tcaaacgatt gatcctaatt ttcctttttc
    11941 aagtgaagat agcactcagc aaattgcaaa gaaaatggcg gatttatcga tccagtcaat
    12001 aaaaaaagca caattgcaga ttgaacatga agatttagat caaatcggta aagtattgaa
    12061 caaggcacag cgaatctttc tttttgcaaa aggtgattct caaatcacgg caaggaaatt
    12121 ccagaataaa atggtcaagt tgaataagtt tttgatcatg gctgaagaat acagtgattc
    12181 ttcttggaat gcagccaatt tgactagcga ggattgcgcc atttttatta gctacagcgg
    12241 tcgcatccat cattatgaac gaataatgac ctatttgaag catgtagagg cccctacctt
    12301 gctgattacc ggaaatcagc attcagaaat ggccaaacag gctgatatgt gtcttgttat
    12361 atcgcaggag gaatatgatt ttgctaaagt agcgactttc tcctctcaaa ttgccttcga
    12421 ttacgtatta aatacgttat tctcagtgat atattctcaa aattttgaag agaatatccg
    12481 caacttgaaa aacaaacaag aattgatgca aaaaggcctt cttaaagaat atcggaaaac
    12541 ttaagaaaag atcctcattt agtaataaga aagatagtgt ttgataggct ctctttgata
    12601 tcatcataaa aacaggctga agttttcttt ttcaaacctc agcctgtttg tttacggaac
    12661 gattcgaata gatatattat agaaatgagg aatagctaac ttctgtttct tattttgaac
    12721 gattgacgaa aaagatatat aagaaggagg aaaatcagta tacatgcagc taacaatcca
    12781 tacaggaaaa atcgtttgtt ctcggatact ttctgtactt ctttttgaac ttcttttgca
    12841 tgataaggaa cccggtgccc tctgacaagt aagcgatgac tgttgaccat ataaggtgta
    12901 caagttagga gtgtcacgaa atcctgccct ttttcgattc tcagatcttt tgtatcagtc
    12961 ggttctaccg tcttgatctg atcgacttga taagcgagtg tccgtccatt gatttcgata
    13021 tagaaagaat cacctaaagt cagtttcggt aagtctgtga acaactttgc ttgaggcagt
    13081 cctcgatggc tggaaataac ggcatgtgta ttttctcccc ccgtaggata agacgttcct
    13141 tccaataatg aggcaccttt ttctagcagc acagtattcg tttcatcaaa aattggcaaa
    13201 tggacattga tctcagggat cgtcaaaata ccgatcgtat gtttctcaaa ataggttcta
    13261 tcctttttcg caggttcttt tttcttagta aagggatctg cacctggatt tccaccttct
    13321 tttgctaatt gctggttttt ctttgtcatg ttttcttgga ttttagccat gacttcttca
    13381 ttttctttga ccgcttgttg ctgataatga gagatgatct gctgatccag ataattattc
    13441 agcgcgtcgc taacaaatgg ataagctagt atccctattc ctgagagaag caagaaaagc
    13501 atcagcagat ctagaagttt ccttttcttt ggtttcattt gtgttctcct tgtgatgact
    13561 gtttgataat aaaagaaaaa ggagcatttg cgtaatccgc tgctcctttt tccaattctt
    13621 gcaaaaagac taaatctgac tgtgcttgcg tctagcaaag tacagtccag caatcagtag
    13681 aaggactact cctgcaccga tatacacata gattccctta ccgcctgttg aaggaagtgt
    13741 acctttgtgt ttatttggta ttttttcagg agaaatcaac tgtcctgctg ttacataaga
    13801 ttgttcatcg atagtaaatg ctacacggtt tgttaatgga acatattttt ctggcgcttt
    13861 cgtttcttcc agatagtacg tgccatattt tagacctgtc acatcgatta aaccgttact
    13921 tgtggttgta aaaaccgttg ctgattcttt cgccgatacc cagctgacgg cttttgtgga
    13981 tgggtcgatc gataaatatt tcgctgtgtc actatcttga tcacgaacga cgaattctgc
    14041 tccagcaagt gtttggtctg atgtaacgtc accatctact ttaacaaatc gtttgccccc
    14101 agtaacgaca tcgactgacg gtggtgtttg atcatttgta tgcccgttat cgacatttgc
    14161 ttggttagaa aatcctttgg ttggatctgc tttttcgttc aaatgcatat agtaaacgaa
    14221 tttcaatgta ccgccaggag ttaatgaagg aatataattc ggatcaactg aaaccgtgaa
    14281 tccgtctgtt tgctcagtga cagaataatt tactgggtcg atttctttat ttccatcata
    14341 taaggcataa gcatacgttc ctgaagaatc attatcaaat gttaaagcag cgtcatgagt
    14401 atcgataagt ttgaatgttg tgtacttgtt ttgcgttcct tctttatcag cgatacctaa
    14461 tgggatattg acagaaatct catattgaat tttttcaccg attgcgacat cttttccatt
    14521 caattgaggt gttgttttat caactttaga cgtatcattt ttgatggtct tttctactgg
    14581 tgtttggcta tttgccagga tctcaaaagg cgtgattgtt tgcttttcaa tcatttccgc
    14641 attatcagga gcttttactt cttctaaatt atattttcca acttctaaat gattaacgat
    14701 caactggcct ttttcaatag atgcctcggc aaagtcattg ttgccgatgt cataagaatg
    14761 accagtaatg aaatgtttgg ctttggtttg atcagttgtc caagtgtaca atccatctgt
    14821 gacactttgg atgtattttt tgacgcttgg tgttccttct tctttagaaa taataaattc
    14881 tgctccattt agtgcttcgt tttcggcagt accgattttt gtaactttca acgttccatc
    14941 attaccgact gtatttttag ggtagagatg gatagtatct agttcttctg tcccgtattt
    15001 ataagagcca tctgcttgtt tgatcatctc atatacaggg aaagctaaaa ccatgtttgc
    15061 ggcagctgac actccgtctt ttggttcttc tttgatcgtg tagactgcat ctttcccatt
    15121 ttgtttttta ggtaaagata aagtgacatt tccatcagca tctgtcgttc ctgaagcaac
    15181 tggtgtacca ggagtcaaag actggactgc ttgttttgct gcatccacgg acgctccttt
    15241 atctcgttgc gcataaaatt cttgagtgac gttataaact gaaaatgaaa tatcggctaa
    15301 tccttggtat tgatcgaatt cgctcatttc tttcccgctg ttttggatta aaggatcggg
    15361 taaatcagtc attttctttt tatgaaggat gacttgagct gctgtctcct ctgcaaacac
    15421 tttttttgcg ccgaagctgt ttgtgagtaa tggtaaaata aggaaaagga ctcctaacat
    15481 aacgtttatt tttttatgat ttttcatttt ttcactcctg ttcttttttt gataaacaac
    15541 cagattgcaa agcttgcgaa taccatacca acaacgccta aaagtgtatt tttcgtttcg
    15601 tttgtttttg gaagaaatgg acggctattt tcttttttat tgactacttt caatatactg
    15661 tccgcctctt tatcctcaga aagaaaagtt gaaatggtaa acggaatttc tgtttcactt
    15721 aaaatataac cagaaggtgc ttcgatctct tttaatcgat aacttcctgt tttcaacccg
    15781 gaaattgaaa aagcgccatt tttatcggaa atcaggtgaa gcgcatctga ttcgttcttt
    15841 gtccacttgt atccgttggc tgtttgctgg aggtaatttc ctgctttgtt tttaataagg
    15901 aatactgcgc cagctaatcg tttatctggt ttatttgtct cgattttgac aaattgctta
    15961 ctccctgtat atacagagac tttctttgta ctgacaccaa aaccaaaatc cagtgttccg
    16021 ttgttgttga tttccttgtt cgcctgtgct gtactgctta gctgcatctg ataagaaatg
    16081 gtcagttttt ttccagcata tttttccaac gaagggatcg aaaataaaac atcaaatccg
    16141 tgaggtttct tgtgtatgac aaagccttct gtcagctttt ctccattcga tgaaatcgtt
    16201 aaactattag gtaaaaacgt taatgcttca tccgcactat ctgacaattc gaacttttga
    16261 tagtcaagga tatttacagg aattgtcgta tgcaaggaat aagtgatttt ttcaccaatc
    16321 gtaaaatcat ttctaggctc ttctaatacc ttctcaaaag gtggatcagg gtagtcgttt
    16381 tcttcatttt taggatacaa atggatagtt gaaagttttt gattgttttg tccatgtaca
    16441 ggaagaacaa ctaccatatt ctctgccttt tctttgacga cttctggtac tttggattca
    16501 atgaaaagat acgctttatc tcttttttct tgatctttag cggccagaga aaaagaagcg
    16561 ataccatctt cgttgttaag agttgtagtt gttgcttctg cggtaaacat accggaagac
    16621 gcaccgtttt ttgcgatctc tgcttgtgct tcttctaccg ttttgccctt ttcccgtaga
    16681 tggtaaaaag aatctgtgac atcataaact tggaatgtga caccatttaa tcctcgatac
    16741 gtttgtaata aagctttttc ttgtccgtca tttggatgat ttttcggcag ttgcccgttt
    16801 gggaaaagca atttgtgtaa agtaatctga accatttctg tttctgtttc tgttgctacc
    16861 tgagtaaaag ctggtttaaa tagtaacaag aagagacaca tactaagcca accaagtttt
    16921 ttcatattta gctgccccct ctttcttttt tcaaaaaaag ataccaaata gaaaacgcac
    16981 aaccaatcat ccctactaga tagattccta aacggccaat tcctcccgtt tcaggtaatg
    17041 gtacttttgc ctgattcgtg atgtctaaag aaatctggtt gtttttggct cctggtgaca
    17101 gaacagattc atgatcttgt ccatccactt gaattgaccc atcttcgtgt ataactatag
    17161 taactggctc ttttagacct tggtatcctt ctggtgtaaa agtttcggtc agcgtataag
    17221 ttccaggttt taaattttcg aatagaaagg tatctgtttc ttgtccatct tttggcgatt
    17281 ctaagtccat ttctggtccc tgcagtctga attttgctcc ttttaatgtc tgtccgttgt
    17341 cttctttttt gtgtaccgtt agatcaaacg cttttagtcg attttgatga gtgagcgtcc
    17401 atacattatt tgtcatctcg gtattttttc ccgtgtaaat gatttttcca tatttatcga
    17461 tttggaattc ataatttccc ggcgaagtat catatccggc aggaccagct gtttcaacga
    17521 ctcgatattt accaggtgtg agtgaatcaa aactggcaag acctttttca ttcgttgttt
    17581 ggctgtcaat tggctgataa gtaccatttg cttctttttt ctgtagggaa aatgctgctc
    17641 ctttaagatt tatctctttg tccgtccctt gcatcgcata cttacgtact gctacaggaa
    17701 cttcaacaaa aggattttca atagtcaact ggatcgtatc atcggaagta gtgactgttt
    17761 ttccatcaat ggttaccgta ccatcagaag cgatcttgat ttcccaagta gtctttttgc
    17821 ttaatccatg cccttctgga gcttttgttt ctgtcagcgt ataggtcatt tctttttgca
    17881 atttgacatt ttctggaaga gaataggttc cgtcgccatg atctgttagt aaagtatcaa
    17941 tagaatctcc tgttaatttg aaaacagcgc caataagatc cttttcacct gtagaggaat
    18001 ttttcgttat tttcaagttt aacggtgtga attgtttagt atttttccat gtcattgcat
    18061 ctatttgttg agaatcgtat cctggtacag gtaattcttt gattgtttgg taactgaatg
    18121 cttgaccttg attattgtat tgaggtagtg ataatatctc ttgataactt tctccgctat
    18181 ttgcagataa tttgtcaatg tctgcacgtt cccacgtatt tgttgtatct ttagctggtt
    18241 taatgattcg aatatatccg tttttccaag ctgcagcatt tgtcgtatgt tcccgttgaa
    18301 tctcaaaagt aacttgatct ggacgatcag ctagattgtt gtcaaattct tcccataact
    18361 ttttgatgtg aagactgact ccgggagctt tagcagatgg tataccgaat tcagctaatt
    18421 cattggtatc aatgtttggc tggaaagttg tcctgccgtt catttgatac cagaaatttg
    18481 gatggaagtc ctcattttct gtttggattc tcacttggta atggatttgg atttcttggt
    18541 cttttcctaa atagatctga ttgctcttga tggtatttcc ttctatggaa atagatggag
    18601 tgaccgttgt aggacttgtc cccacactct tgactgaaag tgtaccaggc tgataaatga
    18661 atggttctgc gattggatca tttatttgtc cattgcttac agttgctgag atctgtacag
    18721 cttttttggc taggtattca gagatatctg ttgcatgatc agctgattca tagtaaagat
    18781 cgcctttttc atctgatgaa accatttgtc gcatacgaga ctctacttct gcttttgaga
    18841 gaccagctgc cggatcgctt tgaagttgga tgccaagacc atgtatttcg attcctcgtt
    18901 ctttgagtgc catcgcttct ccgatggttg cgataaacgt actgtcgatt cttctggata
    18961 gattgttttg gtcaggtgca tcatagattc ttgagattag agaagtattt cccggccgat
    19021 cttgcgtatt agaaaactga gttccgtaat aattgctgct tgattgtgcg tgtacccgct
    19081 gtactttata ggaaaatgtt ggtacaccat ccgtcagcaa aacgatcact tttttatgtc
    19141 catttggaac ggatagcatg cttcctgcat ctcttagtgc tttttgtgta aaagtaccac
    19201 catttgtccg tgaaggtgta atggatttta cttgattttt cactgaatca aatgaaccca
    19261 tctgtactgc accgttactg tagctatatc cttcgcttga gtagccgaca tatcccatat
    19321 tgattttgtc tgtgataccg ctatctgcta aagtatcgac aaaacgatcg acaccaatct
    19381 ttacttcacc gatccgatta ttgtcgttca tacttcctga ccagtctacg accaatacga
    19441 gatcaagagg cgtgatatct ttttgtacat ttccacgagc attcaaataa acatcaaaca
    19501 atccgggtgt acttgtttcc tttgcatact ttcgtatcgc atagtctgct tgattaccgg
    19561 ttcctccata ttcgatatac gaatgggtcc gatcattagg atctccattc caagaattta
    19621 taccatccca ttgatttgtt ccgtttttat tgccttgatg atcaagaaca tttgtatttc
    19681 ctgtaggttg ccaactggct ttaggataag tgccctgatc atctgttgta tattctgtag
    19741 gaatcgtttg attagatggc acactcacag ctggcaagga taatgtaggc aatgtaaatg
    19801 ggctgacaga attttcgttt tcttttgatg attcttcttc tatttcgtct ggctttggta
    19861 ctgacacatc tgtatctttc ttattttctg tctcatcaat aatgtcatat tctttattat
    19921 cgacgatcag cttgtttgcc tggctgtggt aaagtgctgg atcgattgga aaactcagat
    19981 cgatagtttg tttagtgttt gatgagattt ccaacgtaat tttcccgcta tttacctgat
    20041 aagcatagcc atctccttct tttctttcca catcacttaa gtaattttcg actagaccaa
    20101 tttctttttc tatcttttca gcactggtgt tattcgcatt tagcttgatg ttcagtgctt
    20161 tttttccaga ctgatccgaa atgacttcag ctgaaattgt ttctaaaact gttggatcat
    20221 ctgtagtgtc tgctattgca gataatggca caaagtttga taaactcaat attatcagca
    20281 tgaaaataac tttcagtttc ttccctgtgg tcgtcatttt tcccctcctt tttctttttt
    20341 tctgttttga cgtgaatagt gaaaattatt aaaataaaca ggcgttacat aattttattt
    20401 attttaatat gataattatt atacgaaggg cgctaaaggg aatcacacca attttcatac
    20461 caattggttt catttatgaa gttgattcct tcgattaatg agcgtttcat tgaaagaaaa
    20521 gggttgaggg agaaaaacat atgatcaggt tgttggaagg aaactataga aagatggaaa
    20581 aaatcattcg aattctgtcc atttctgaca agtggatgac taaaaaagaa cttgccaaac
    20641 gaattggtag ttcagaatct acatttgtaa ggtatatcga agagatcaaa atccgctggg
    20701 gaacggatgt aacgattcaa tcttcacaaa aattggggta tcgtcttgaa catttgaatg
    20761 taccagctta tttaaatgtt ctgatggaaa tgtcgcaaag ttctacaaac agtcgtttat
    20821 taaatgagat tattgtcaat ccgggtaaaa cgattgagta ttattgtgaa aaaatttcca
    20881 tcagccggtc ttcttttaca cgtaagttga aacaatgcaa tcaaatttta gaaagctatt
    20941 tattaaaagt gatcgttgac caaggttttc agttaactag ccttaaaagt gagctccagt
    21001 tgcgtatctt tgttaccttt ttctttttaa gttactacgg aagacgcacg ttgccatttc
    21061 caatcgaaaa aaagaagatc aaagaaatta tggtcaagaa taattgtcag atgaatttgt
    21121 ttcaggaaga aagcccatat gagcaatctt tctttattat gtattttgtt gtgcatctca
    21181 tgagagaatc ccaaggaact ccatttgaat ggaaagctgg agactcttat gtacagttga
    21241 taaatatcga taaaaaagac ttcttaatct tgaaaaatct cttaggaaaa ttgaagtaca
    21301 gcagctatat aaaagtagtg aactattttg tcaatacgat tttttcagaa ttttcggaga
    21361 aagaaaaaaa tgaaatcagt gagcagatac gaaaaaatat gtcctactgt tcgttttcat
    21421 ccgctgattg caaagaaaaa aacgaagaat atgttgttca attattaacg caaatttatt
    21481 ttttctcccg tattttccca tacgatacga ctcatttgac gatccgtgca acttactttg
    21541 cacagcagat gcaacaccgc cagatacgtc tatatgctgg atttcgtgca gaacttcaat
    21601 tttattccac tctactgaat cagaatctga tttattattt atctagctat atcttttgga
    21661 tgcttatcgg taatcctgaa attcaccatt atacttctga taaaaaaata ctgattatca
    21721 gcgacttaag tcttcgacat agtcaatata ttgaagaata tatcagtgat attcttgctg
    21781 tgcataaaat tcactctgag acaactgcta ttactgaaga tcagctgtcg aaatacaatc
    21841 ttctcgagta tgatctgatc gttacgaatc aacccatttt gaatgcccat gttcctcata
    21901 tattgattga tgatagtgtg tcattcgcaa atgaagaaga actcatccgc ttattcgagt
    21961 tatgaataat caaaaaacag ctatgtataa accaccctga taaaaatttc aggacaaata
    22021 cacatagctg tttcttttta ttgtattcct tcagcaatcc aacgagattt atagcgaaag
    22081 tcttttaaca actcttcttt tgtccaatta tttgcaatga gatccgtcaa agtgttcatt
    22141 acgagggtca tggaaaagta taggaaacta actgcttctt ccgacgattg aatggagaaa
    22201 tgattgattc ttaataattc cagccatttt tcgttcattg gagaatcagc cgatagttct
    22261 ctacgtttgg ttgtctgctg atcatttcgc tgggttaaca agtataacct ttgccaatag
    22321 atactttcgt gatctaagtc gcagcaccac tctaaatatt tttcgatccc caaaaagaaa
    22381 tgttgtttgt tttcgctaat gaattttaag atatcttgat ggactatgtg agaactgctt
    22441 ttgatcgtat acaaataagc atcttccaaa tcttgaaaat atttataaaa agcaccgcgc
    22501 gacatcccca tcttgtcaac gatttctgag actttgactt ggctgatgtg ctgtgagcaa
    22561 aatatctcca gtaataggtc atcgattctc tgtttctttg cgttcgataa attgaaaaaa
    22621 gtttcttttg gcatccacat ctctccttta tctctgatta tacgtggata gcccttcatt
    22681 gtcatgaagg attcattcct tctttttctc ttcttctgtc aagtacccat cttccattcg
    22741 ataaacgcga tcactccatt gaatcatacg gacatcatga gtaaccataa tagtcgcttt
    22801 ttgtttctca tgagcttctt taactagtaa tttgacgact tcatatgcat gatctgtatc
    22861 caaactagct gttggttcgt ctgctaagat caagcttggc tcattatata aagcgcgagc
    22921 aattgccact ctctgtcttt ctccaccaga aaggtcttta ggataactat ttttaagtga
    22981 ctggatatct aaagattgca gcaaggaatc gatttttgtt gaatcttctt tttttgaagt
    23041 aacttggtca actagttcaa attgttcctt taccgttaaa aaaggaatca aattagagct
    23101 ttggagaata aatcctattt ctttaaagcg taaatctgct cgtttttttt ctggaagctc
    23161 agttagtgag tgaccgttga tcactatttc tccggaagtc ggtgtttgca atcctcctga
    23221 aatggtaagg aaagtacttt tacctgaacc agaaggacca atgatgctga cgaattctcc
    23281 ttcctttaca taaaaatcaa ttgctttcaa agctgagacc tttgtatgac cagaaccaaa
    23341 tgttttggta acttttttca tcgttaatat ttttttcatt tttattaacc tcctattgct
    23401 gtaattgggt ctactttggt tatcgtacgt atcgaaaaca atccgcctag cattgcgaca
    23461 atgatcaaaa tcccactata tagcaaccat tgtgaccaaa aaacagcaaa aggcatcgcg
    23521 cttggtaaaa tcagactagt caaataagca aacaaaagag caagcagaac gcctaccacc
    23581 ccaacaataa aggactgtgc tactaaagat ttagcgatga agaaattttt gatcccttgt
    23641 gctttcatta ctccaaaaat agcagtcttc tgaagtgtca tcacgtacat gaaaataccg
    23701 accacggcag caaccactaa gaacaaaaag tatatcatcg catttaaggt catattttgg
    23761 gcagaatagc caggaatact ttcaatgaat gtcccaatag ttaataactg tagacccttc
    23821 gatgcttttt ctttcgaaat tttagctgaa tcctttatta cgatcccatt gatcggctgt
    23881 tcttcttcag aagcaaacgg ctgttgtcca tacttcaaag cagtccacgt atctagggac
    23941 gcatagatga cgggagaaac tgtgtaataa gtttcaggaa agataccgac aatcgtcaaa
    24001 ggatcgtcgt aactgccaat tttgatcgta tctccaattt tatagcctga atcagccaga
    24061 ttttgagaga tgatgatttc attctttgtt ttaaattcat gccctttcgt gagttttggt
    24121 aataaaaatg cttctttcgt tgtgccgaaa actgtaacat tttctttgtt ttttcctttg
    24181 attgctccgc tgtacaatcc gattggtgct ttctctcctc cttcaatgta tttcagatct
    24241 cctcttgtta attgtgaagc tgcaaatact tgatttgcat cctccgacaa aacaatctct
    24301 tgtgcgtccc aatcatcgat tgctttttta aactcttctg aaagtccatt cgctagtcct
    24361 gacaacatga atacgacata cgcaatcaag aacataatac cgacgatcaa gccatatcgt
    24421 aatttagaat agcgaatttc tttgatagct agaaacattt gtttttcctc cctatgatag
    24481 attgatagtg acaaaatgtc acttgttgaa tagtgtaact ctaaagtgac aatttgtcac
    24541 ttgtgttgtt tttttcttat caataaattg tctaagacat ctttcgataa aaccttaaca
    24601 tgagtcataa aaaatttatt taagccttat ttatgctttc catgataaac taaagtgacc
    24661 aaatcaatga ggtgggaaaa tgattaaact attagtagta gaagacgata aagtattatc
    24721 caataatata aaagaaatac tcgctgcaat cggcgagata acacaagttt atgatggtag
    24781 tgaaggactg ttcgagttgg aaagtggagt ttatgatctt gcaatcttgg atttgatgat
    24841 gccggaaatg aatggatatg aagtgttagc aaaaatacgg aaagaaaaaa tacagactcc
    24901 agtattgatt ttgactgcaa aagatagttt ggaagataag attgaaggat ttgaacgagg
    24961 tgcagatgat tatctaacaa aacctttcta tcgagaagaa ctgatcatgc gcgtgaaagc
    25021 attattgaaa cgctcgctag gtctctttga tgaaaatgtt ctgaagtata aggatatcag
    25081 ttgtgattta aaaagcaatg aagtcttgta taaagaacaa gttttgccca tacaaggaaa
    25141 agagtttgaa ttgctcgttt attttttaca aaataaggga atcattttga caaaagagca
    25201 gatatttgac cggatctggg gatttgattc tgatacgacg attacagtta ttgaagttta
    25261 tatgagcaac ttacgaaaac atctgcgaag tactggattg gataaagaaa tcaaaacctt
    25321 acgtaatgtc ggttatatac tgcaaagggt gtgatgcaat gaatggagat attacacgaa
    25381 agcaacgtag tcgctttttt gcgacaaatg tagcagcatt tgcttttatc ttttttcttt
    25441 tgggattcat tactttacag atattaaacc aatctgcata cagagaaaca gatctgtcat
    25501 tagagaaaat aaattttgat tctcgaacag tacaattaga gatacaaaga tatcagcaag
    25561 gcgatccctt tttaaacccg actcaaacgg aacaaaacag aacaaacatg gaacagccat
    25621 taatggaacc atcaaatgac cgttttaaca ctcaagtgat cttgtggtct aaaaatggtg
    25681 agatattgaa taaagcagct attggtgggc gtttcaacca aatcaaagaa ttaaaaatgg
    25741 atacgaaaaa tctgaatacc atccaaaata ttgaattaaa tgaagacagt ggctcatctg
    25801 ccctctcttt ccgttcgatt acgaaaaaag cggagacgaa tcaagatggc gttgcctaca
    25861 tccaaatttt agaaaataca aatcaaatca agaattcatt agcgactttt cgcacgatta
    25921 tgattttgtg tatgattgtt ttttggattc tctctattgg tatcagttat tacttgtcta
    25981 gtctaagcat gcgccctatt attctttctt ggagaagaca aaaagaattt gttgagaatg
    26041 cttctcatga attgcgcaca ccgttaacga ttattcaaaa tagtttggaa catcttttta
    26101 ccaagcctaa tcatactatt attgaagaat ccgaaagcat cgctcaagca ttgtcagaga
    26161 cgaggcgcct cactggattg acttcggatt tgctgacaat cgctcggaat gattctgatc
    26221 agcagctgct ttcaaagcaa atgatcaata cacaagaata tatcgaacaa cttgttaaac
    26281 catttcaaga gatggccatc atagatggaa aagagtttat tctccataac gatgcaacat
    26341 tagaagtacc aattgatgaa aaaaaaatcc atcaagtttt ggttattttg ctggataatg
    26401 cattaaaata tacgaatcca gaagataaga tcattttgga ttcatctgtt aaccataaag
    26461 aatggctgat tcacgtaaag aatactggcc cttctatcag tgaagaagat caagcaagga
    26521 tttttgatcg attttatcgg gaagatcaat ctcgggcgaa agagactggc ggatacgggc
    26581 ttggcttggc aattgcaaaa caggtaatcg aacagcatca tggacagatt tctgtatcca
    26641 attatcttcc acaaggagtc gattttaaag tccaattgcc gttgaagcct aaaaaataat
    26701 gcttatccct aaaaaagggc tgtgacaaaa atcttgtcac agcccttttt tgttgcgaat
    26761 aaacggtgtt ccagaagtag cttcttcgga aataagccga aatttcttta agctgaccac
    26821 ttctgtcaca acctctttag cttacgctta cgatttttta ttgcggtctt caatgtgtac
    26881 atcaccgctt gtgtcaatat ccaattcttc tcggctaaca tcttctgtca ctttttcaac
    26941 atcttcatgt tcttctttat gaatcccaac ttcttcacga ataactgtat gtttgcttac
    27001 atctacttgc tcttctttga ttgggatagt aatcgtgtca tcttccaatt tttcgtctgt
    27061 tccctgtgaa gattgatctg ttactggttt gcgttcgatg acgatttctt cacgtttgac
    27121 cggtacttct accgtttcag tatcgttgac cacatgtttg tggatgtcga cttctccagt
    27181 tgtcacatca tgtgtattta catctaattt ttcttctttt agttgaattg tatcatcatc
    27241 tagatttggt ttgcgatcga tgtcttcagt cttgcttgta cccattgtat cagtctcgcc
    27301 aggtacgtcc atcggatcag ttcctggtgt catattcaat ggatccgttg tattttgaaa
    27361 gcctgtcgtg ccacctacgt ccattggatc tgttccagtg ccagtttcta atccagtccc
    27421 cattgtgctt gctgggctaa cagtatcttg tgtatccatt gtatcttctg ttgtttctgg
    27481 ctgacgatag ccttttactg tgatgacaaa ttttccatca gaaatatctc ctctatattg
    27541 atataaagga tcattttctg gtgtagccgt ctcagaatca taggtatcaa aagaaaaagt
    27601 atcttttatt ttttcccata aagaacggtc ttcttcacca tccatccgat tttcatctgt
    27661 ttcaacatct ataccagaca atccgtcaaa tcctagtcta gatgctgctt catcagtagt
    27721 ataaataacg atatcatctc gttcataccc ttcgttacgc aaccgttcaa ttactgataa
    27781 tgcttcttcc ctcgtactat agcttccgat gaccgttaaa tttttctctt ccatgtaaat
    27841 tcctcctagc aaatagattt atgattggta
//
LOCUS       DACGDM010000026        27719 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.026, whole genome shotgun sequence.
ACCESSION   DACGDM010000026 DACGDM010000000
VERSION     DACGDM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.026"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(241..2133)
                     /locus_tag="IXR05_001254"
     CDS             complement(241..2133)
                     /locus_tag="IXR05_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259791.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2130..3857)
                     /locus_tag="IXR05_001255"
     CDS             complement(2130..3857)
                     /locus_tag="IXR05_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259792.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3873..4523)
                     /locus_tag="IXR05_001256"
     CDS             complement(3873..4523)
                     /locus_tag="IXR05_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4259793.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4727..5023
                     /locus_tag="IXR05_001257"
     CDS             4727..5023
                     /locus_tag="IXR05_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4259794.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5195..5815
                     /locus_tag="IXR05_001258"
     CDS             5195..5815
                     /locus_tag="IXR05_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAQ4259795.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5907..7073)
                     /locus_tag="IXR05_001259"
     CDS             complement(5907..7073)
                     /locus_tag="IXR05_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4259796.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7085..7438)
                     /locus_tag="IXR05_001260"
     CDS             complement(7085..7438)
                     /locus_tag="IXR05_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4259797.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7566..8588
                     /locus_tag="IXR05_001261"
     CDS             7566..8588
                     /locus_tag="IXR05_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAQ4259798.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(9027..9461)
                     /locus_tag="IXR05_001262"
     CDS             complement(9027..9461)
                     /locus_tag="IXR05_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259799.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9571..11430)
                     /locus_tag="IXR05_001263"
     CDS             complement(9571..11430)
                     /locus_tag="IXR05_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4259800.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11548..12708)
                     /locus_tag="IXR05_001264"
     CDS             complement(11548..12708)
                     /locus_tag="IXR05_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAQ4259801.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13015..14439)
                     /gene="araA"
                     /locus_tag="IXR05_001265"
     CDS             complement(13015..14439)
                     /gene="araA"
                     /locus_tag="IXR05_001265"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAQ4259802.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14455..15153)
                     /locus_tag="IXR05_001266"
     CDS             complement(14455..15153)
                     /locus_tag="IXR05_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4259803.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15110..16771)
                     /locus_tag="IXR05_001267"
     CDS             complement(15110..16771)
                     /locus_tag="IXR05_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAQ4259804.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            16989..18389
                     /locus_tag="IXR05_001268"
     CDS             16989..18389
                     /locus_tag="IXR05_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAQ4259805.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18641..19720)
                     /locus_tag="IXR05_001269"
     CDS             complement(18641..19720)
                     /locus_tag="IXR05_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4259806.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19806..20765)
                     /locus_tag="IXR05_001270"
     CDS             complement(19806..20765)
                     /locus_tag="IXR05_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAQ4259807.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20777..22300)
                     /locus_tag="IXR05_001271"
     CDS             complement(20777..22300)
                     /locus_tag="IXR05_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAQ4259808.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22310..22873)
                     /locus_tag="IXR05_001272"
     CDS             complement(22310..22873)
                     /locus_tag="IXR05_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAQ4259809.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22879..23742)
                     /locus_tag="IXR05_001273"
     CDS             complement(22879..23742)
                     /locus_tag="IXR05_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4259810.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23756..24652)
                     /locus_tag="IXR05_001274"
     CDS             complement(23756..24652)
                     /locus_tag="IXR05_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4259811.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24827..26098)
                     /locus_tag="IXR05_001275"
     CDS             complement(24827..26098)
                     /locus_tag="IXR05_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259812.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26088..27605)
                     /locus_tag="IXR05_001276"
     CDS             complement(26088..27605)
                     /locus_tag="IXR05_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAQ4259813.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
BASE COUNT         8095 a         5845 c         4791 g         8988 t
ORIGIN      
        1 cgtttggttg ggcttattac cgcagatgca agcttttgaa caccgtttaa ggaagaggtt
       61 gtaaaatcag cggtttgacc tgagtattag agatacaaaa cggaaaaata gcttctcata
      121 ttttgccgtt ttttgagcta ataccgaagg acagctgatt gaacaccgtt tattcggaaa
      181 aagggactgt gacacgactt ttgtcacagc ccctaaaaaa aataataaat ttgtactatt
      241 ctatgaagct tcttcttcag aaaactgact gttataaaga tctgcataga atccgtcttt
      301 ttccatcaat gtatcgtggt ttcctgtttc tacgatcgaa ccatgattca tcacaataat
      361 gttgtctgca tcgcgtattg tagacaagcg gtgagcaaca acgaaacttg tccggttttc
      421 caataggcgg ttcatcgctt tttgaatcag tatttctgtt cgtgtatcta cactagatgt
      481 tgcttcatca aggatcagga catctggatt tgctaagaat gcccgcgcaa ttgtgattag
      541 ctgacgctgc ccttgcgaaa tattgcttgc atcctcgttt aatacagtgt tatatccttc
      601 tggcaattta cgaacaaaat cgtctacgtg agcagcttta gcagcctcaa tgatttgttc
      661 gtctgttgca tcgtcgttcc catatttgat attgtcatag atacttcctg taaacagcca
      721 agtatcttgc agtaccattg aaaactgtgc gcgcaattca tcacgtgaaa gatcacgggt
      781 atctacacca tcgtaacgaa tactacctcc agaaacatcg tagaaccgtt caagaaggtt
      841 gatcagtgtc gtcttccctg caccagtcgg acctacaata gcgaccatct caccaggttt
      901 gacatccaag ttaaaatcag tcattagcaa gttatctggt gtgtagccga attgaacatt
      961 ttcaaaacga actttgtatg gtgtatcttt ttcttctgga aggccagatt tttcattgga
     1021 catctcttct tcatccaaca cttcaaatac ccgttcggct gaagcaactg ttgattggat
     1081 agtgttcatc aaacttgcaa gttgagtgat tggttgagag aactgtgttg tatattgcaa
     1141 gaacgcttga acatccccta atgtcatgtt cccatttgca acttttactc cgcctagtac
     1201 agcgacgaac acatagccta gatttttaac gaaattcatc aacggcatga tgattgccga
     1261 aataaattga gctttccaac cagcggcata cagattctga ttttcttttt caaatacttc
     1321 ctggtctttt tcagtatgat tgaatgtttt aacaatggta tgaccaccat atgtttcttc
     1381 tacttggtta ttcaataaac ctaaactttt ttgctgatct gcgaaaaaca cttgtgattt
     1441 cggcgctacg atcatcacga tgatcaagct taaagggatc atcaataacg cgactaacgt
     1501 caattgccag ctgattgaaa gcatcatcac gatgacccca atcaatgtga ctgcactagt
     1561 tacaaattga gtcaaatttt gctgcagcgt gcttgcgatg ttatccatat cattgattgc
     1621 tcgagacatg atatccccat ttgtatgtgt atcataatag gaaatcggta cacgattcat
     1681 tttggcttcc aaatcatgac gtaattcata aactgttcgt tgggaaacac gtgtcataat
     1741 aaattgctgt aaaaagttga atacagcaga aatcaaatac atcacgatta ctgtcgcaat
     1801 gatctgcgcg attttatcaa agtctatcgg aaattttgtt acttgttggc cttgttgcat
     1861 ctgttgagcg ccagccatta cacctttgaa tatttctgtg gttgctttcc ccaagacctt
     1921 tggtgtttgg atttggaaga tcacggctgc tattgctagt acaaatacag cgatgatcgc
     1981 aaccatacgt ttagacatat agccaaacaa tcggcgtacc gttccccaga aatttttagg
     2041 cttttcacct tttacaccga gatttctgcc aggtccacca tgtcctggac cgcctgctgg
     2101 tccatgagag ggacgtgtgt ttgttttact catgctaagt cctcctctct tagttgtgaa
     2161 tgaacgattt cttgataagt ttcgtttgtt gctaatagtt cttcatgtgt tcctttgcca
     2221 accagttttc cttcatctag cacaaggatc atatctgcat ccattactgt acttactcgt
     2281 tgagcaacta aaacggtgat actttctttc atattcgttt tcaatgcttg gcgaagattg
     2341 gcatccgttt tgaaatccaa cgctgagaag gaatcatcaa acacatagat atctgctgtt
     2401 ttgactaatg cccgtgcaat tgccagacgc tgtctttgtc caccagagaa gtttcctcct
     2461 ccttgttcca catggctatc taagccatct tccatctctg aaacaaaatc tttagcttgt
     2521 gcgatttcta atgctttcca aatcatttca tctgttgcat ccggcttacc atactgcata
     2581 ttgtctcgga tcgttccaga gaacagaact gctttttgag gaacaaagcc cattaattct
     2641 cgcaaattat attgagtcat gtcactaatg tccgttccat ttatttggat cgaaccagat
     2701 tcgatgtcat ataatcgagg gatcaaattg actaaggtcg ttttacctga accagtcccc
     2761 cctatgattg cgacgatctc gcccgacttg gcttggaaat caatatcttc caatgcaagt
     2821 ttttctgctc catgatatcg ataattgaca tgattgaagg ccaatgttgc gttttttcca
     2881 gcaaaagaaa ctgttttagg attttcaggg tcatggatac cgattttttc atccaacact
     2941 tcattaatac ggtcagctga agcttgtgca cgaggcacca tgataaaaat agcggaaagc
     3001 atcataaagc tgatcaagat ctgcatcgca taagtcataa atgcaatcag attaccgact
     3061 tccaaagtca tatctgctat gtagtgtcca ccaaaccaag tgattgctac gtttgtaccg
     3121 ctcatgatca atgtcatcat tggcatcatc aatgcgacga tcgtattaac tttgattgcc
     3181 gtatttgtat aatctttatt cgctaaatca aaacgatttt cttcaaagcg tgtcttatcg
     3241 aatgctcgaa tcactctgac ccctgtcaat ccttctcgaa ataccaggtt taaacggtca
     3301 gttttctttt gcatactttt gaataatgga acagcaaagt acatgattcc gccgatcaaa
     3361 ataatcatta ctgggatgac aactaagaag atttttgtca actgatgatc tttttgataa
     3421 gcaagtatgc tcgcgccaat caacgtgatt ggtgcattga tcatcatacg taaaaacatt
     3481 tgtgtaacca tttggatttg agtcacatca ttggtcgttc ttgtgatcaa agaggccgtt
     3541 ccatatttat caaacgcatc ttttgtcaga ctctctgatt ttttatagac atccgtacgc
     3601 aattgcttac ccagtttctg tgattcacga gtagcaaaaa atgtatttgc gatagcagct
     3661 aagatactga tcaaagaaaa gccgatcatc acaaaacctg tatgccaaat ataatcgaca
     3721 tctccttgcg ctaccccttt atcaataata ttggaggtaa gtgtcggcaa atataaatct
     3781 gccagtactt ggatcaccat gaaaactgca gctgcaattg ctgaagtcaa ggagatccgt
     3841 tttacgattt ttagcatcta gttcccttct ttctatttat atactccgtt tttcagccaa
     3901 gaaagtttca aattgaattc actgattgct tgctctactg agtaatcttc agatgttgaa
     3961 aataagcgat acgaatgcgc aattgttgta aatacagtat tcatcactaa ttggatcagt
     4021 aattccaatt catgatcatt ttttactttc agcttcgtcc gatcgatcaa ttcaagcaac
     4081 tcttttgcat cttgtttgtg ttctttatgt ggatcgtgag gcgttttttg gcgactcgta
     4141 tgaggagcga cttttcttga ggcacggtaa tccatgttca taaacaagtt acgataaaaa
     4201 gaagcattct cgccttccaa aatctcataa atcattttag aaaaatagga ttcgaatcct
     4261 ttgaatagat caccatcgga ttctttcatt agttgtaaca tatctttaga gctgtcacgt
     4321 ctcattgtct caaagtaata aaaataaaga tcctctttat cttcaaaata ctgatagaaa
     4381 ctgcctctag ggatatccgc taatttgacg atattagcaa tcgaagcttc ttttaagggt
     4441 actctagaaa actcgattct cgcagcctcg attagtcttt tttgtttttc tttaggcaaa
     4501 tggaaaaatg tctgtgtcgg catatggatc ctcctttctt tcaagatgac acattgtcat
     4561 atgacgctgt gtcattataa cacctcctac ctgttttgca agacatttgc atagtttttt
     4621 tcattatcat ccgatacatt aaaaaagtga taagaggaat ccttccattt gaattaatga
     4681 gagttgccca ttaaaatagc cacatactaa acaaaggatg agataaatgg cccaatcaat
     4741 tagtgtccaa gacttcaata aattgcctct cgatgctgac agcatcgttt tagatacaag
     4801 aaatacctta gattacacaa aaaaccactt aagccactcg ctttctatcc ccgctgctat
     4861 cttgccaaga caattaaaaa atctagatcc aaagaaactt tattatattc taagctatac
     4921 aggcaggcga tcagaagcat tagccgatca acttactgct aatggttttc gtgctgttta
     4981 tatcattggt gggatggaag ctcttcagtc gagtgttgct tgaatattgc ttgttagatt
     5041 caaaagaggc tgtgacaaaa aatcgtgtca cagcctcttt tataccctgt ctttttttag
     5101 ttatttattc ttcaacctta tcaatatgac ttgatagcct tttctttttc tcatagttat
     5161 aacaatcata gcaataaaag gagaaggtaa gcatatggca tctgttttag tagtcaaagg
     5221 tcatccccta actgcagaag aatcgcgcac agttaaggca ttgacgtctt ttttaacaag
     5281 ttataaagaa aatcatccag atgatgaagt gactgttttg gaactttatc gcgatgatat
     5341 tccggaaatc gatgaagaat tattatcagg ttgggaagca ttacgtgctg gtgcagaatt
     5401 cacttcctta tcagaaagtc aacaacaaaa aattgctcgt ttcaatgaat tgactgatca
     5461 gttccttgct gctgataaaa tcgttatcgc aaacgcctta tggaatctaa atatcccaac
     5521 aaaattaaaa gcttggttcg ataccgtcaa tgtagctgga aaaacgttcc gctatacaga
     5581 aaacgggcca gaaggattag tgacaggtaa aaaagcactg cacatccaat ctaatggcgg
     5641 tgtatacaac ggacaagact ttgcctctca atatgtaaaa ggtattttaa actttgtagg
     5701 catcgatcaa gtagatcagc tattcatcga aggaatcgat tatgaccctg accgtgcaga
     5761 tgagttgatg caaaatgcat tagataaagc tgctgcttta ggtaaatcat tttaaaaatt
     5821 gagataaatg catacaaaag agacagagga aaaaatcttc aaagcagcat ttgtaccttg
     5881 gatattttcc catctgtctc tttttgttat tctttctgct ttttcaacgg attttcttca
     5941 taaagagaag agattgttgt gtaccattca aaaacatgag taatcactac tttagctgct
     6001 gcataaacag gaatccccaa gatcacaccg atgattccga acaatttccc agaagtcagc
     6061 agaactaata aaatcgttac tggatggatt gctaactgat tccctagtac taatggagag
     6121 atcaagcgtc cttctattgt ctgctctact gcaaaaacga tcagtacttt gatgatcatg
     6181 aatggacctg ctacaatggc taaaaagata gccggaatca tcgctaaaaa tgatcctaag
     6241 taagggatca ggttcaaaaa acccgcaata atccccaacg tgacagcata ctctaaacca
     6301 atgaccgcaa aaccaatcat aaacatgatt gccacagcaa aagccacagt tagttgtcct
     6361 cttatataag aagaaacttg actattcatt tcactcagca cattcaacgt cggtttttgc
     6421 atgcgtgtcg gtaaaaattt gacaaaataa ggtgctaatt gtttaccgtc tttcaataga
     6481 taaaataaga taaacggcat cgtcagcaga gccactaaaa tagtcgctac cgcgccgaca
     6541 aaacttccaa gactctgaac tgtactctta gatatatctt ggatcatatc gcctgccgaa
     6601 ttcatgaact tatcacctgc tgtttccaac tgttcgcgaa attggttgaa cagcgggtcc
     6661 cgcaaaatct cggttaattt attatcaatc gtatctacat attgagggaa gttactgatg
     6721 aagctcactg tttgttcctg aatcttaggg atgatcacta cgctccccca tgcgattagt
     6781 gcaacaacca aaacaaacag cccaatgata ctgtaaagcc ttggtacttt tcgcttttca
     6841 aagtaatcaa ctaccggatt catcaagtaa tacaagattc ctgctaaaat gataggcaga
     6901 cctacgattg ctaaaaattg ccagattggt gcaaacaaat atgaaacttt tgtaaataaa
     6961 aagacgatca gcaatattaa caatacaaca agtaaggctg tgactacttg attatttaaa
     7021 aaccagcgcc aaaaccacga taccggtctg ttcttcttat tttttccttc cataattcct
     7081 cctgttagtt ataaaaaatt tggcttccca aaccaatagc aggcagtcta tgcggatgaa
     7141 gatagattcc atttgcaatt tgtccttctt ctggacaagc atcaaaaatc aatgatacgt
     7201 gagctactgt ctctaaattc ccattggcca tcggaccgac ataatcgatc gtatatacct
     7261 gatcatcaaa agcaattgtt ccgcctgctt tcaaagaaaa aggttcgtct tttgatactt
     7321 cttgaatcac cgaatatttt cgtaaggcag ctgttgctgt tttatcgaac aaaatcagca
     7381 tgggttcttc cttgtttatt gcttctgtcc caatttctgt aatctttgcc tgaatcattg
     7441 cactctctcc tttaattgct ttcaaaaaca gtataacaca ttctcattct ttagccgtgt
     7501 ggaataatta tgtgatagaa taaaaacgaa aactatttca ttacaattag gaggaatcag
     7561 ctcatatgat cgaaaagata attttaggaa cctatacgcg tcgcgaaagt aaaggaatct
     7621 atacgatcga ccttgataca gaaaaagaag aattagccaa cctttcatta gctgttgaag
     7681 aaaatagccc tacctatgta gcaaaaagta aagctggcaa tctttacaca gttactagtg
     7741 tggatggatt aggtggtgcc ggtgcgtacg ataaggattt tcattttttg aatgcggtaa
     7801 cagagtctgg cgctcctttg tgttatgtag cggttgatga agcacgtcaa ttactatacg
     7861 gggcgaacta tcataaaggt gaagtaaatg tctaccatat attaggagat ggcgaactga
     7921 aagcagcaga ttcaatattc catcaagaag cgacaggtcc tcataaaaac caagatcatg
     7981 cgcatgtcca ctatacggat ctgactcctg accaacgatt agtcgtatgt gatcttggta
     8041 cagatcgtgt gtatacttat gatgtgtccg aaaacggcaa attgaatctt gtaactacct
     8101 tcactgcaga gccaggaaca ggccctcgcc atcttgtctt tcatccaaat ggacaattcg
     8161 cttatttatt tggtgaatta gacagcacag tccgcgtgct ttcttataat aaagaaacag
     8221 gtgcttttga agaattacag aaaatatcga ccttgccaga agaattcgac ggtgaaaatg
     8281 gaggggcagc tatccgcatt tcaaatgatg gcaagttcct ttatgcttct aaccgaggac
     8341 ataactcgat tgctgtattc gcagtttttg aagatggttc ccacattcaa aacaagcaaa
     8401 tcatctcaac agaaggggat tttccccgcg atttcgcact agatccaagc aataattttg
     8461 tcgtgtgtgc caatcagaac accgataatc tgacattata tcgccgtcat cctgaaacag
     8521 gattactgga attactgaaa aaagatgtct atgtaccaga atgtgtctgt gtttattttg
     8581 atcgttagta agaaaaggag aatgaaatga atcagcaaga cgtattagac agactacggg
     8641 aagaactaaa tattcctttc tttgatggga aaatcgaaga taaagagtat agcgaagagg
     8701 aatatcagaa actcaaagcc gatttacaga actactttga acaatatgta cagaatgtag
     8761 aaaactaatc agctttccat actatctgaa aagaacatca ggacaagact tttccgtcta
     8821 tcctgatgtt cttttctaca aataaaaaac cgccgagatg gttagactcg acggaaaagg
     8881 agtatttact cgattttgag taagtacaag gttgttgttg gttataggta tgtcattatc
     8941 ataaaggatt ttgatcactc tatcataaag gtaatattac atttatatta gataactcta
     9001 gtttttattg ttatcaaaga tttcttttat tttttcaaca acaaattagt cattttttgg
     9061 atggcagctg tcaattggtc tgtcgcttgg tcttgttttg cttcagatgt attgaataga
     9121 tcttcatcta cccctgattc aagatcgata ctttggatca tttcttcaca gcctgctaca
     9181 tatgaaagat aagctttttc aaaattttta tgaatgccca ttgcttttgc tggtggacgc
     9241 aaagtactga ctttcttaag cattgcccga tatttttttg ttccttcttc aaataacagg
     9301 atgatctctt caagagtcga tttgtccagt tcacttgttt ttccttcatc aattgcgttt
     9361 ctgatcactt catatttcgg atgcattcct tctccgattg cttctgtttc cttgacgatt
     9421 tgatcgatgg actgcacata atagccaata ttcggtaaca tgttcgtttt cctactttct
     9481 ccattgttgt tattatttat tctacttgtt tttatcctca aatgacaagt acttgaaaaa
     9541 atttaatggt ttctatacag ctcgccattc ttattcgtgc tcaaagaaac catctgctaa
     9601 actatattgt ttccctgcga caatgtcata ttggatcaat tgatattcgt cgtaaatctc
     9661 ttgttgcgag cgattgaatt gcgcttcttt ataccactgt ccgttttgat agtacagttc
     9721 tcgttcaaac gccggaagtt cctgttctaa tgataaaagc agctgataaa agccatttgt
     9781 tgtctgattc gtctgttcca ttagattcgc tgcaaaataa aacggactgg tgattgcatc
     9841 gtgagtcgtt tgcttttcta attctccttt actgtcgaac ataagaaatt gtgtttcatg
     9901 caatgtttgt ttgtcatttt ttgcttggat cgtatctgaa tagatccctg gaagatgatc
     9961 cccccaaaaa acaactaaag tccttctaga aagattcttc aattcttccg tgaactgctt
    10021 cagtgccgtg ctgctatagg aaatatcttg cagataattc tctaagtcaa gtgtcccact
    10081 tccatctgaa gtttttgcag gatagtctag attatcatac tttccatcgt agggcatatg
    10141 tgtctgcatc gtgactaaat gaatgaactg aggtgttttt tcttccttga gaagtgtcat
    10201 tacttctttg taagctgact catcagaaat atatggatta ttctctatcg tatccgtata
    10261 ggtcatcgta cgctcgctga tgaactggtc aaatcctaat gtctgataaa catcctctct
    10321 tttatacatc gaagtattgt atggatggat cgctgtcgtc tggtatgatt gtgcgtttaa
    10381 cgctgaaacg atagaaggaa gctgatccat ttttggtaca agcatcgtgt aaggggtggt
    10441 gagttgcgca ttaaataacg ccatagaaaa accagtcaat gcttcaaatt cgatatttgc
    10501 tgttccaccg ccatagtttt gagaaagcat attgccacta tatgtttgat cagctacttc
    10561 ataataatct gccaatggct caccagatac ttctacgccg tttaatcgac taggatctga
    10621 gaaactttca ctcatcacga acacgatgtt cggcgactct tcctctacag ttttattttt
    10681 ttcatcggct agcttctggt atttttcagt gatttctttg atcttttctt tcgaatatcc
    10741 ttcaggttca tccattggtt ctaccttcag attgtacaaa aacccaccga taaaaccagt
    10801 gttatagtag ttcattttct ggctgtaagg tatccatagt gccgttttat tatatgcttt
    10861 tcgcaacaaa ttatcgggat tgttgaaatt actgatatac cctagcagtc caattgccac
    10921 aagcagtgtc gttaatcgga tcaattggaa tcgccttcct tttttcaggc ttcgaaacat
    10981 gtaccagcaa aacaatccta tcacggttcc tgcggcagct aagatcactg taaacagcat
    11041 agtgccggtc atatctttca gcaatccgat ttcagtgatc atcttcaaat cgtctggata
    11101 aatcggttct tgccgataac tcattttcat ataatttgca aaacctaata caccgatggc
    11161 tacgacatac gtaagggaac ctaaagggac agatcctgct agtgcaatca gaaaaataag
    11221 aataatcagc aagacgagac aggctaagaa gaatttttcc gtatgccaag aaaaagcaaa
    11281 tttcaacgca aggtctacgg atagatcatt ttgacaccac tgcaaaaata aattactaaa
    11341 aacaacaaga aaaaagatac tgatgattgc tgctgttcct tttaaaatct ttttctgttt
    11401 ggtcgaaagt ctgcttatat atcttttcaa atgcttgctc cttcatttct atcaataaaa
    11461 gaatgttgct tctcttattt tagttgtacg aaattcgaaa gtaaagaacg gaaagaagaa
    11521 ttaatgaaat ccaaatattc tctttcttta tggcctttct ggtttcttta ataagcggac
    11581 ctttcgtact ccagaaattt tttctagctg ttgtttcact tgattgagct gttcaaaatc
    11641 agtactgtct atgtcaatca atatgtagac atgctcattc ttatggttac gcgatatatc
    11701 tgcgatcgct agctcgttct cattcagcag agaaaatatc tctgctaata tattggtttt
    11761 cttttgataa aatatagtga atcgaaacgg cgcttggaaa aacattcgtg cggatggata
    11821 attgaccgct tctctaaccg taccgaacaa aagataatct tttaaggctt caactgccaa
    11881 acgtccgctg tctgccaaag cttcctgagt cgatccccct agatgaggca acataagtat
    11941 acggtcattt tctaagaact cttcttctgg aaaatcagtc aagtatttag ccagatgttg
    12001 tttttccaat gcttgcataa cagcatattt atcaacaatt tcacttcttc ctacattgat
    12061 aagtacagca tcttttttca ttttttctat attcgcctga tcgatcaatc cttttgtatc
    12121 ttctgtcaac ggcagcatga ctacgatgta atccgaggta gaaagaactg tttctaaatc
    12181 tgcttgccga acataatcca actgggcatc gcggatagaa taacccaaga catccatccc
    12241 taagctatag caacttagcg ctacttttgt gcctatcgct ccaagaccaa gaagaccgat
    12301 ggttttgcct tgcaattctc gtcccacata agcacttctt ttgttttctg cctgttctaa
    12361 aatattagga cctgttagtg tttgtaccat acgacttgct tcgattatcg gacgggaaga
    12421 taagagcaaa cagcacaaaa caagctcttt tactgcatta gcatttacac ctggtgtatt
    12481 catgacgatc gtcccgtttt cagaagcttt ttcaacgttg atcgtgttca ccccaacacc
    12541 agctcttgaa attgctagca aatctggtgt aagccattca tctttcactt tcgtactacg
    12601 aataactatt ccttcggctg gcaaatcatc tattattttg aaatattccc cttgtaactt
    12661 ttctatctct tgttctggaa tagcatcaat caaatgaacg tgatacataa aaccccctcc
    12721 ttactaacaa gtatctcgaa atttctgcaa ttagacaact gtttaccatt tgacttccta
    12781 gaagcaaaaa gagcagttag agcagagtag gctgagtgat aaaaataagg ctatgacaag
    12841 ttactgccat aagccttatt ttcgagagca aaatattgag ggtgagatat cttgataaat
    12901 ggtgttccgt tagctgacat tgataataag actaaatttc aaaaaagttg aaaagcaaat
    12961 ttcgtcaatc tcttcttatt tcttaaaact aagtggcttt ttcacaacct ctttttatct
    13021 aataaccact gtttccaact caactaattt tgcccacgtt tcaatttgat ctgttgttag
    13081 atttagcgag acaacggtat gatgaccgcc acctgcctga atccatgaat ggacaccttc
    13141 atggaaattc ggtttagttt tccataacac acgtgcaaca ggtaaattag gtgcttcagt
    13201 cgttggttca aaggcttcta cttcattgat cagcagttta taatgcgtac cgaaatctgc
    13261 catcgatacg actacccctt ctcctgcttt cccatcaaat acaagacgcg ccggatcttc
    13321 tctatctccc attgataaag gagaaacaac gattcttggt ttcgtcgcag caagcgtcgg
    13381 atctacttcc atcatatggg attccaagat tgcttcttgg ccactagcta gctcgtaagt
    13441 ataatcttcc atgaatcctg tatctttccc tcgagccatg attttcagca accgatcaat
    13501 cgctgcagtt ttccagtcgc cttccccagc aaaaccgtat ccttctgcca tcaaacgttg
    13561 tacagctagt ccaggtagtt gtttcattcc atacaggtct tcaaaattag tcgtaaaagc
    13621 gttatagcct ccttcttcta agaaacggcg aataccgatt tcctgctgag cttgtacttt
    13681 tacatgttcc tcccatgtct tttcttcata atcaccatag tcgaaggtat acaattcctt
    13741 gtactcttca aataattgat cgacttcttc gtctgatacg cgatcgatta cttgtacaag
    13801 atctccgata ccaaaataat caacagtcca accaaattga atctgtgctt ccactttgtc
    13861 tccttctgtg acacccacgt ttctcatgtt gtcaccaaaa cgagccactt ttattccaaa
    13921 actttcatta taggctactg caacatccat ccaatcagca atctcttttt ggatctcagg
    13981 tcgtttccag tagccaacga cgattttatt ttgtttattt aatcgagcat tgatgaaccc
    14041 atattcgcgg tcaccatgag cggattgatt taaattcatg aaatccatat cgatcgtttt
    14101 ccaaggaatg ctttcgttat attgcgtagc taaatgaagc aatggttttt gtagaagctt
    14161 tgtcccgcgg atccacattt ttgctggtga gaaagtatgc atccaagtga tcacacctgc
    14221 tacttcttct cgataattga cctctttcat gatttttgtg atcgtatcag cagtaactgc
    14281 taattcttga aggcggattg gataaggcaa ttggccattt tcattcagtt catcgaccat
    14341 ttcttgtgca tgtttcttta cttctcgcag tgcttcttcc ccatataaat gctgtgatcc
    14401 tacaacaaac caaaattctt tttctccaat attcaacata attagccact ccttttattt
    14461 gttttgtccg taatacgcat tttttccgtg ttttcgtaaa taatgtttat ctaaaatccg
    14521 ttgaggcagc tcttctgaaa atgaattgag ctgtctggta aataaattca tcttgcatac
    14581 ttcatctagt acgactgcgt tcattaccgc actttgcgca tctttccccc aagtaaatgg
    14641 accgtgtccg tgtaaaagta cccctggaat tgctaaggga tcaattttgc gttctttgaa
    14701 tgtttctatg ataacttttc ctgtttcata ttcgtacccg ctgtcgattt cctgttgtgt
    14761 caaaaatcga gcacaaggta ccgatccata aaaagtatct gcatgcgtcg tccccatcgc
    14821 aggaacatcc aatcctgctt gtgcccagat cgtcgcccat gtcgagtgag tatggacgat
    14881 tcctccgatt tgaggaaatg aacgatataa aacagcatga gtaggcgtat ccgaagaggg
    14941 attgagttta ccttcaatga tatgattgtc caagtccaca acgaccatgt cgtctgctgt
    15001 catctcttca taactgactc cgctaggttt gataacgaaa tatcgtgttt caggatcaaa
    15061 agcgctcaca tttccccatg tatatttgac gagtccgtgt ttaggcaagt caagatttgc
    15121 ttggtatact tcttctttca gttgttccag cattttctat cactcctttt tcttgcaatt
    15181 gatgaatcgc tgttttttca atgtcgatcc cctcacggta acgtctcata aatatctgat
    15241 agcctgctat ttcttctgct gaaggtgtga tggtgattcc ttggtcttgt ccaaacacgt
    15301 cttctgccaa gaagttttct aaagacttcc catgtcgatc catcatatag gctgctaata
    15361 acgcgattcc ccacgctcca ccttctccgg ctgtgtccat cactgtaact ggtgcctcca
    15421 tagcagatgc tagaatccgc tgtccaactt ctggtgtttt aaaaatcccc ccatgcccca
    15481 ctaaacgatc aatttggaca ttctcagatt tcaatatatc cattccgatt ctcattgcac
    15541 caaaagcact ggctaaatgg atccgcatga aattcgctaa atcaaaacgg ctacctggtg
    15601 tacgtacaaa taatggcctt ccttcattta ctcctgtaat gttttcaccg gaaaaataac
    15661 cataagaaag taatcccccg caatccgtat cgccttctag cgctttgttg aataataccg
    15721 tgaataattt atctctgctt atctccatac ccaaagaatt ggtaaattct tcaaaaatac
    15781 tgacccaagc attgatatcc gaagagcagt tattcgtatg aaccatgcct actagttctc
    15841 ctgaaggtgt agtgaccatg tcgatttccg gatggacatt ttctagttct ttttctaata
    15901 cgatcatagc gaaggcggaa gtaccagccg aaatgttccc tgtccgtttg gctacactgt
    15961 tcgtagcgac cataccggtt cctgcatccc cttctggcgg acaaaccggg attcctggtc
    16021 tcaaatttcc cgtagggtcg atcagataag cccctgattc gcttaacttg ccagcttctt
    16081 ctcctgctac tagaacttta ggcaaaatgt gatccaagtc aatcgctacg tgcgcttttt
    16141 cgattaactg accaaaaata tttttcattt cttgatggta ggttttcgtt gaaggatcga
    16201 taggaaacat gcctgatgca tctcctacgc ctagtacttt ctcaccagta agctgccaat
    16261 ggacataacc tgcaagcgtt gtcaaaaaat taatttcttt cacatgttct tctttattca
    16321 aaatagattg atacaaatga gcgatactcc atctctgcgg aatattgtat tgaaattttt
    16381 ccgttaatat tcgttctgct tcttcagtga ttgtatttcg ccaagtacga aatggtacta
    16441 gtaactgttc cttgctatca aatgctagat aaccgtgcat cattgcactg aacccaatcg
    16501 acccgattgt cgtaagattc tcgccataga tttcgaatac ttctgctgcc atttttcggt
    16561 aactgacgcg cagtcctttc caaatatctt ctaatgaata ggtccagata ccattttcta
    16621 gtttgttttc ccactcataa ctaccagcgg caataggagt aaaagatgaa tcaatcaata
    16681 cagctttgat cctagttgat ccaaactcaa tccctaaaga tgtacgacca tctatgacat
    16741 ctaacatact ttgcgcattt acttccttca taatgattta actccctcct tctcgtcaaa
    16801 cctgatcaaa ccgtcttttt agtagcgctt acaatgatta ttgtatactt ttgtacgtac
    16861 atgtcaagcg gttatttaca agaatacaat aaaaaacact tgttttgtac gtacataagt
    16921 tataaaatga aattgcttac aaaatctgat caaccgcctt ctcgaaattc tagaaggaga
    16981 gaatacttat gaaaaaagaa aaaaaagttt cctcatcgtt tatttatttt tttggcgcat
    17041 ttggcggcat tctatttgga tatgatattg gtgttatgac cggcgcctta ccttttttac
    17101 agcatgattg gggtttggca ggtaaagctt ctttgatagg atggatcacg tcttcggtca
    17161 tgttaggtgc gatccttggc ggctctttat ctggtcttct ttctgataag cttggacgac
    17221 gaaaaatgat tcttctttct gcacttattt ttatggctgg ttctgtcctt tctgcatctg
    17281 cccctcacaa tggttcttat tttctgattg cagcaaggat tcttctaggt ttagctgttg
    17341 gcgctgcatc tgccctagtt cctgcttata tgtctgaaat ggctcctgct agactaaggg
    17401 gaagattgtc agggatcaat caagtgatga ttgcttctgg catgctcctt tcctatgttg
    17461 cagattattt gctaaaagtg ttgcctgaaa cgatggcttg gcgcgtgatg ttagggctcg
    17521 ctgctgtccc cgcgctgatt ttatttttcg gtgttttagc tctaccagag tcaccgcgtt
    17581 ttcttatgca atctggccgc ttggaagagg caaaaagagt attgaactat attcggacac
    17641 caaaagaagc tgaacaggaa ttcgaacaaa tccagctgaa tgtcaaacaa gaaaagacaa
    17701 ccggaacttc ttggcatact ttgtttttag aaaaatatcg ttccttagtc attgccggta
    17761 ttggtgtagc agtattccag caatttcaag gagctaatgc tattttttac tatattccgc
    17821 tgatcgtaga aaaagcgact gggcatgcag cgagcgatgc attgatgtgg ccgatcatcc
    17881 aaggaatcat tttagttgct ggttctttgc tctttttggt tattgcagac aagttcaatc
    17941 ggcgaacttt attgaaaata ggcggtagcg tgatgggact ttcattcatc ctaccagctg
    18001 ttttaggaac tgtactggat gctcatacaa attcgttgtt gattctcttg tttttatgta
    18061 tttatgtcgc attttattct tgcacatggg ctccactgac atgggtaatc ataggcgaaa
    18121 tattcccact agctgtccgc gggcgagcat ctggcctagc ctcttctttt aattggattg
    18181 gttctttcct agttggcttg ctttttcctg tgatgactgc ttctatgtct caagaaatcg
    18241 ttttcggcat ttttgggatc atctgctttt taggggtttt atttattcaa gagatcgtac
    18301 cagaaactcg tgggaaatct ttagaggaaa tcgaacaaag tgcatctaaa aaaacttatc
    18361 ctaaacgtat ttctatccat cattcttaaa gaggttgtga cagaagtggt cagcttcaag
    18421 aaataagaag gaaccgctta gtttccagtc acaaggaaca atttcaaaaa acagcttctc
    18481 atgtttgatg aatattgtga cttgtgacca gttggtagga gaacaccgtt tagtggagag
    18541 gtggtgaaag aaacgttcag ccttgagcga tgacaaaagc tctcacaaac attgcgacga
    18601 gtaaccgtag gagcaataag aggcggtaaa aacccgtctc ttatttttcg ttttctttca
    18661 ctgtttcccg ttcaactagt acaggttcat agagaatatt tggctgtgcc tgtccttttt
    18721 caatcgttgt gacgatccac cgtgcggcat cttgtcccaa cttttctttt ggatgcgtca
    18781 atgttgtcaa ttttttattc cctaaatggc ttaaagaaga atcgtctgtt cctacgatcg
    18841 ataggtcatc tggaatatga tagccatttt ctgtcaactt atctagcatt aaactagcta
    18901 tttgatcgtt atagcaaatg atgccatcta aagcttgttc ttctttcaac cgttgtactg
    18961 ttttttcagc gattgtttct cgtgtttccg tggtgaaagt aatgatatct tccgtcaaaa
    19021 aacgcacatt atactgttca cacgcgctga taaaaccttt catcctgtat tttccttgaa
    19081 gatcgtcgat ttttgtgatg aacaacagac gctgatgtcc tttttttatc aaatattctg
    19141 ctgccataaa accgactttc acatcatcta aacaaatata agaggcattt aactcttcat
    19201 aagcagcatt gatcatcacc atcggaatgc cttgttctct caaagcaaca taaagtgcta
    19261 agtttgggtt atactgatta cttttcgtag gctcaacgat caaaccatct accccataag
    19321 caatcatttt cttcaaacac tctttctcca attcgtgatc gttattcgta ctggctaaaa
    19381 gcaatgaata cccagattct cgtaattcat tttcgattcc tcggataatc gacggaaaaa
    19441 tataatcaga gagatatgtg gtgatgacac cgatcgtttt tgttctgttc aatggtgttt
    19501 tttctttctt atagctgtca tctacatatg tgcccgaccc tttttcttta cgcagatagc
    19561 cctcatttac caacacagcg attgcttgcc gaatcgtatg tctgctgacg tcatatattt
    19621 cttgcagctt gaattctgag ggaatggttg tatttacttc gtattcctca cgaaggatct
    19681 tttgttttat ctcttctgca atatcttgat attttgccat ttgccttgcc cctttttatt
    19741 tgtacgtaca tatatcataa cgagtctgca aggtttattc aagcaaaaat caaggtttct
    19801 tgtgctcata aggcatacgg aacaggttca ccaaattctg gaaatccttg ctcattccac
    19861 gtaaagcatt gcgcgttcgc gtgccgatta ggattgtcta acggatcccc tttttggttc
    19921 ttctctggtc gagcatgata gatcaaaata tcaaagcacc cgtcttctga aaccgtaaac
    19981 gagttgtgac caggaccaaa ttgcttattt ttttcagaag aaacgaatac tggctccgat
    20041 aatttatgcc atgattcttt taataaaaga ttcttgtgct catcagccca cagcaggccc
    20101 atggcatagt tttcatctgt tgcactacca gaatacgtaa tgaatatttt cccattgcga
    20161 gtaaggactg ctggaccttc atttactgaa aaaccccgtt tttcccattc atactcaggt
    20221 atagaaagga ggatctgctt cccctttaac gtccaaggat tatccatttc ggatagataa
    20281 agattagaat tcccagtaat ttcaggatct tgttgggccc acacataata tagctttcct
    20341 tgagaagaga aagttgttcc gtctaaactg aaagtttccc ttttcgtttt tatttgtccc
    20401 ttttctatcc aatctgtatt cattggatct atatgctgat tttcaagtac gaacatgcgg
    20461 tgatgatgag attcatcacg tatagtttta tgattgcttg cagcaaagta aatataccat
    20521 tttccattga tataatggac ttcaggtgcc cagatcaatt cactcatcgg tccttcttca
    20581 tgagcctgcc atacaatcag gcttgcagca tgttctaatt cattcagtga ctttgccctt
    20641 cttaattcaa tcacttggta gcctggaacc gatcctgtaa aataataata accatctgta
    20701 tgtttatata cccaaggatc tgcccgttgc cgaacgatag gattattata aagtgtcttc
    20761 atcataacaa atttcctcac attttcttta ttctaattac attccaagag tatttttcta
    20821 tccctacatt taattcgtca tgtttttcta ttgaaaaata gtttatttca ggttttattt
    20881 tttctggttc ttcacgtgta tttttgtcca acagatcgct actggttaat gtgtagtgct
    20941 ctccttgatc tagcaaattg aaatcatgtt caatcgttat cttttgttgt tcatttgtgc
    21001 gattgatcaa gaaaatagtc agctgattgc cgttatctac gatcacactg tccacataag
    21061 gaacattttt tatcttttca caatcataaa cagggcaaat gatttgttgt ttcaatactt
    21121 gacctttagc atatttcgat aagtgttgca tcacataata agttggattc ctccatgctt
    21181 gtcctttagc atctgtcagt attaaaggta ttgtgtttac taacaatgat tgacaactaa
    21241 tctttacgcg atctgcgtgt cgtaaaatag ccagccctaa tgaaccaaat aataatgtat
    21301 cttccatagt aaagtaacac caatcgatgg gactaccgac ttcaaaatcc ctatgtcttt
    21361 tttccggttg ggcatgtaca ttccattcat caaacgctag atacattgtt ttctcacttc
    21421 tcaaatatcc ttttacataa tcacaagtag caacgatttc ttcaatttga cgatcgaatc
    21481 gataagcttt tgcaaggtat gtcgctgtat catcacgctc atttttagga ggtttagtca
    21541 agtcttcttc atcatactta tcaatatagt tatgcaaagc taaataatct acattctcat
    21601 aagcttcttc taatgcgata cgatcccatt cagggtacga tggtaaacgt ggcgtagagc
    21661 ttccaactaa gattgtttca attgaatcat ccactaactt catgactttt gaggcttcat
    21721 ttgctaacct accatattca taagcactct tagcccccac ttgccatgga ccgtctagct
    21781 cattccctaa acaccataat ttaacgccaa aaggcttttt ttgcccattt tttattctta
    21841 aatcactcca gaaggttcct tttggaaaat tacaatattc tactaaattt tttgcttcat
    21901 caattccttt tgttcctaaa ttcaccgtga atatcggttt cgcttgtaca tgactgatcc
    21961 atttaaaaaa ttcgtggagt ccaaaagaat ttggttctat acctcgccat gctaaatcaa
    22021 ttttttttgg tcgttgttct ttcctaccta cagtatccac ccaatcataa ccagatgtaa
    22081 agtttcctcc aggatagcga atgacaccta attctaattc ctttacataa gagaggacat
    22141 cttgtctaaa cccgtcacca tcagctgttt catggcccgg ttcataaatc cctgtataga
    22201 cgacacttcc catatgctca acaaatgagc caaacagccg agaactgatc tctcctaccg
    22261 taaaatcctc tctgattttt actttcactt cttcgtccaa cagctttccc tacctttcat
    22321 ttcctatagt caagataata gatacaagtt tccatacgcc accagcaaag ataaaaataa
    22381 aaggagggaa aagaaatatg agcagtacaa atcctaataa caatacgcaa caaagaatat
    22441 ttctcaaaaa atcaaaaaat actttccatg cactttgttc aaaaatttgt aaaaatgtga
    22501 tatctttgtt ttcagaaatc acatatatcc aggataaaag aaacatggaa taaataagta
    22561 aaactacata tccactaatt gaaagtacga ttgtctgttc ttctaataat tgattaacaa
    22621 gaaaataaat aatgatcgtt aacagactaa ggaacaagtt cttaccaaaa tgttgcttta
    22681 ttccttgaaa gaaaaaataa atgatatttc ctgatccctc acctttccat tgcgccatta
    22741 cataaaaaac agcacatgta gcaggcacga tagtaataac aggcaaacac acgattaccc
    22801 agagaatacc taataagatg taatcagaaa ccacaatcaa ctgtccataa aatttagtct
    22861 caactatttt catcttcctc actctttcat tccagacata gctgttcctt gaacaaaata
    22921 tttctgtgca aaaatataaa ccactagtaa tggcagcatt gaaataaccg ttccagccat
    22981 tacaggtcca taaaaagaaa tgttctgccc tgtaaataaa gctaaccctg ctggtaaagt
    23041 tctcattttt gaactacttg tcaatatcaa tggataaagc aagtcattcc aactattcat
    23101 cagcgtgaaa atccctaatg ataaaagagt aggtttgctc aatggcaaca tgattttcaa
    23161 aaaaatatta aactcactta atccatcaat gcgtgctgcc tcttccaaag aatctggtaa
    23221 agtaataaaa aaggaacgca tcatgaagat accaaatgca gttgtcatac gaggaatgat
    23281 caaacctgca taagtatcaa gcatgccaag caaattgact tcaataaata gaggaatcat
    23341 gaagacttgg aatgggatca tcattgtcag caaaacgaaa tagaacaaaa ctgattttcc
    23401 tttgaaacgc atacgagcaa atgcataccc cgcaagagaa tcaaagaata cagaagtgat
    23461 cactgtccct ccagcaaaaa tcactgtatt tttgatgtaa tctaataaag ggatcgttgt
    23521 ccaaacctta atatagttat ctagggtata gctatctgca aatattctag gcggaaatga
    23581 gataatgtct ttttcgtgtt taaaagaaga aataatcagc cacaaaaaag gaaacgcaat
    23641 aaccaacaat ataactagca tactaatcgt tcgaatgatt tttttaccac taactgcttt
    23701 tcgactattc acagtaactg taatcgagct ttctggtgcc atacaggttt ccctcctatt
    23761 tcatttgttt ttctttccgt gacatgtaca cattagtgga gatagctata gttgcaacaa
    23821 tgataaacaa aaccgaagac agtgctgatg catagcccaa ttcataaggt gctgtaaatc
    23881 ctcgactgta aatatattga acagctgttt ctgtcttaaa ttgtgggcca ccagcggttg
    23941 caacatatac ttggtcaaac acttgcatcg aaccaatcag attcgttaaa atacaaaaac
    24001 ctaaggaggg aacgatctga ggtagcgtaa tgttaaaaaa ctgctgtcga tttgttgcac
    24061 catccatttg agcagattca tacaaagagg gagagattcc ctgaatagca gtcaagagaa
    24121 tcgtcatagt aacaccaaaa ttcttccaaa cagtcatgat ggctaccgtc ggcatagcaa
    24181 gggttggatc gcgaaaaaat tgagggatcg gcaagccgac ttgtgaaaac aagtaaggaa
    24241 tcgcccctac attcggatca agcaacatag aaaaaataat cgcaattgac gtcaatgaac
    24301 aaataactgg aatgtaaaat gtcgaacgac aaaaacgatt gaatctggta tttttagata
    24361 atgctactgc tgctaataaa ccaacgataa tttgtgttgg cgtttcgagt acggtgaaat
    24421 ataaagaatg aatcaacgaa ttaactgctc gttcatcact aaatatacgt gtgaaatttt
    24481 caaaacttac aaaatttctt gatgtaaaga aaatattcaa atctgtaaaa ctaatagcaa
    24541 atgttcctaa aagcggtatg acagtaaata ataataaaac taaaaaagat ggagttaaaa
    24601 acaaatacgc agcacgatca ggacgattcc aatatttggt gaatccgttc atatagtcca
    24661 cctcatcttt cattttgata aaatatacaa tcttggttta aacgaatctg aataagatat
    24721 ccgaacaatc gctgtgattt ttgcaataac acctatctgc aaatactagg tcgatcattc
    24781 agatatctgt atcttgccaa cagtctatcc tgtataaagt tctgtactat ttttgcagta
    24841 attgattgat ggcatcatct gcatcgttca tgagtgtctc aggatcttct cctgctaata
    24901 atttttcaat cagtggattg atgatatcgt tattgatcgc agagatttgg gtaaaacctg
    24961 gtaaatatgg ctctgcatag tccatttgtt tcgataattc agatacaata ggatcatttt
    25021 ttacttcttc atcttttgct actgaatcca agtaggcagg aaaaccattt tcgatactcc
    25081 attttttacc aatttcagtt gtattccaat atttcaaaaa ctcatagaca gcttcttttt
    25141 tattattatc tgtacttgcc ggaatggcat atcctacgcc atctaaaata gctgtttttt
    25201 tgtctgaatc actcccttgt ggtaaggtag tcacattata atcaatctcg tttgctttca
    25261 atccgttatt taaccatggc ccattgattt caatggctag ttgaccagca ttcattaaat
    25321 tgtccatttc ggcgccagaa atcgattctg gaccagtctt gtctacatgg atcatttttt
    25381 ggatcgcttt taacgtttta aggttctcag gagacgcaaa ttcagactta gtataatcat
    25441 cgttcactaa tttaccgcca tttgctaaca tccagttata taacggtgca gttccatcct
    25501 tattgaagac aaaacctgat acatttttac tactatcagt taattttggt gccatttctg
    25561 tcaattcttc ccaagtagta ggtggttgtt cagtatctaa tccagcttgt ttaaacaaat
    25621 cattattcca atacatatac atgccttgta cctgcatggg gacaaaatac tgtttacctt
    25681 ctacttcacc taattcaata gccgtttctt taaaatcaga tttatctact ccatcatatt
    25741 cccagaaatc gtctaatggt tgtaccgctc cgttttctac atactgtgca aaatctggat
    25801 aatttaatgc aataaagtca ggtgcttttt tagaagaaat cgctgtagga agtttttcat
    25861 tcaaattggc ccaagtcatg atatccattt caattttgat gtttttatca tttgttttat
    25921 taaattcatt aacgatttct tgcaatattt caccatcaga tgcagtaaac ccattccaaa
    25981 aagtcaaagt cacttcttta tcagaatcag attctgctga acttccgcca ccgcaagctc
    26041 ctaaaatacc tgttgcagct accaacaaag agccaattaa ccatttttta cctttcattt
    26101 tttgttcctc cttcatctga taaacgacat ctgaccacat tccaagatag cggtttcaat
    26161 aaacaattga ttttcccatc ttcagctttt acatttgttg aatgacttgg ttttacttgt
    26221 tcacttttag gaagattagt tgcttttgta tcaaatccac tcatttcaga aaaatcaatc
    26281 actccctcta atgataattc agacaagtga acagttagat tcatttcttc ttctccacgg
    26341 ttaactgcaa atatgacaag ttctttgtca tttattacgg ctatactttc taaatacggc
    26401 acttcttcaa aatcttccgt cgcatagttt gctgaacgaa tttgtgggct taacacctct
    26461 ccttgtccat acacagcagc ttgcataaat ggataataga tcgtctgtct ccaagcttct
    26521 ccgtttgttt ctgtcctgat tggtgcaata acgtttacca attgagcaag acaagcaatc
    26581 tttactctat ctgcatgttt caataaagtg attaatagac agcctaatag taatgcatct
    26641 tcaaaattat agttatcttc tagtaaagga ggagcaatct gccaaggcgc tgcttgctca
    26701 tcttgttccg ctgaatgata ccaaatattc cattcatcaa aggacaggtt gatctgcttc
    26761 ttactatgtt tcttcgcctt gactgtatcg cacatcgctg tcacttcaga aatgaaccga
    26821 tccatgtcta aggaacgtgc aagataatga gaaagatcat ttttttggtt gccataatat
    26881 tgatgcagag acaaataatc tatttgatcg tacgcttgat caagaactgt taactcccaa
    26941 tcaccaaatg taggcatttg ccgattcgaa cttccgcata aaaccacctc aattgaatca
    27001 tctacgagtt tcatcgcctt agccgtttcc tctgctaacc gtccatattc ttccgctgtt
    27061 ttatgtccaa tctgccaagg accgtccatt tcattcccta aacaccatgt cttaattcca
    27121 aaagggctct cttgaccatt cgaacgcctt aaatcactcc aataagttcc tttaggaaaa
    27181 ttacaatatt cgactaaatt acgagctgca tctactccac gagtacccag attgacagcc
    27241 atattgattt cggcccccac atgctgacac cagttataaa attcatgaat cccaacttca
    27301 ttcgtttcaa ttgtccgcca agctaaatcc aaccttctag gtctatttgc tatgggccca
    27361 atactgtctt cccaacgaaa tcctgacaca aaatttccac caggatatct aatcatggga
    27421 atgttcaatt cttttaccaa gtgaatgacg tcttggcgaa atccactttt attagctgat
    27481 ggatgatctg gctgataaat cccttcatat actgctcgtc ccatatgttc aataaatgaa
    27541 ctgtacaacc gcggatcaac tttgcctaca cgcttgacac tactaatcaa cattgtggct
    27601 tccataactg acctccttta atttatacat gaataataca cctcgttgaa agcgttgtca
    27661 ataatataaa tgttaaactt acttattttt tatcgatttt aattaaccaa aatattaat
//
LOCUS       DACGDM010000027        27677 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.027, whole genome shotgun sequence.
ACCESSION   DACGDM010000027 DACGDM010000000
VERSION     DACGDM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.027"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            161..808
                     /locus_tag="IXR05_001277"
     CDS             161..808
                     /locus_tag="IXR05_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAQ4259814.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            892..1836
                     /locus_tag="IXR05_001278"
     CDS             892..1836
                     /locus_tag="IXR05_001278"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAQ4259815.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1971..3422
                     /locus_tag="IXR05_001279"
     CDS             1971..3422
                     /locus_tag="IXR05_001279"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAQ4259816.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3443..4279
                     /locus_tag="IXR05_001280"
     CDS             3443..4279
                     /locus_tag="IXR05_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4259817.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4279..4938
                     /locus_tag="IXR05_001281"
     CDS             4279..4938
                     /locus_tag="IXR05_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4259818.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLNWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5064..5753
                     /locus_tag="IXR05_001282"
     CDS             5064..5753
                     /locus_tag="IXR05_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259819.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5759..6715
                     /locus_tag="IXR05_001283"
     CDS             5759..6715
                     /locus_tag="IXR05_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAQ4259820.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6759..7271
                     /locus_tag="IXR05_001284"
     CDS             6759..7271
                     /locus_tag="IXR05_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4259821.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7527..8075)
                     /locus_tag="IXR05_001285"
     CDS             complement(7527..8075)
                     /locus_tag="IXR05_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4259822.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8164..9345)
                     /locus_tag="IXR05_001286"
     CDS             complement(8164..9345)
                     /locus_tag="IXR05_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAQ4259823.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9581..11089)
                     /locus_tag="IXR05_001287"
     CDS             complement(9581..11089)
                     /locus_tag="IXR05_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAQ4259824.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11248..11439
                     /locus_tag="IXR05_001288"
     CDS             11248..11439
                     /locus_tag="IXR05_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259825.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11642..12559
                     /locus_tag="IXR05_001289"
     CDS             11642..12559
                     /locus_tag="IXR05_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAQ4259826.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12552..13625
                     /locus_tag="IXR05_001290"
     CDS             12552..13625
                     /locus_tag="IXR05_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259827.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13773..14291
                     /locus_tag="IXR05_001291"
     CDS             13773..14291
                     /locus_tag="IXR05_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259828.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14272..14664
                     /locus_tag="IXR05_001292"
     CDS             14272..14664
                     /locus_tag="IXR05_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAQ4259829.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14740..15675
                     /locus_tag="IXR05_001293"
     CDS             14740..15675
                     /locus_tag="IXR05_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAQ4259830.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15808..16587
                     /locus_tag="IXR05_001294"
     CDS             15808..16587
                     /locus_tag="IXR05_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAQ4259831.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16580..16897
                     /locus_tag="IXR05_001295"
     CDS             16580..16897
                     /locus_tag="IXR05_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4259832.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17141..18751
                     /locus_tag="IXR05_001296"
     CDS             17141..18751
                     /locus_tag="IXR05_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4259833.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18908..19756
                     /locus_tag="IXR05_001297"
     CDS             18908..19756
                     /locus_tag="IXR05_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4259834.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19987..20466
                     /locus_tag="IXR05_001298"
     CDS             19987..20466
                     /locus_tag="IXR05_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259835.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20499..22727
                     /locus_tag="IXR05_001299"
     CDS             20499..22727
                     /locus_tag="IXR05_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4259836.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22856..24499
                     /locus_tag="IXR05_001300"
     CDS             22856..24499
                     /locus_tag="IXR05_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4259837.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(24572..25117)
                     /locus_tag="IXR05_001301"
     CDS             complement(24572..25117)
                     /locus_tag="IXR05_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAQ4259838.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(25140..25625)
                     /locus_tag="IXR05_001302"
     CDS             complement(25140..25625)
                     /locus_tag="IXR05_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4259839.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(25615..26427)
                     /locus_tag="IXR05_001303"
     CDS             complement(25615..26427)
                     /locus_tag="IXR05_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAQ4259840.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(26566..>27677)
                     /locus_tag="IXR05_001304"
     CDS             complement(26566..>27677)
                     /locus_tag="IXR05_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAQ4259841.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         9059 a         5035 c         5531 g         8052 t
ORIGIN      
        1 ttttttgtct aacttctagg attgtctcta aagcttagtt tctttttctt tatattttca
       61 taataaaagt ttggttcttt aatttttaaa catgacagaa aattttttct tcgttatact
      121 tgtaatagaa tactatttta taacaaaggg gatcgaatca atgaaaaaaa ctgttattta
      181 tactagttta tttgcagctt tgtttttagc tgcttgtcaa tcaaatacca atcaaggcac
      241 atctgggaat acgtcttcca gtagcgaaca gcgctcttca caggtatcgg actcctcaac
      301 aaaagcaagc acatcttcgt ctagccagac aaaaagttct agtgaagcaa gtactcagtc
      361 agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc caagataaat acccagatac
      421 tgcaattact agtttggaat tagatagtga ttggggatct tacttctaca agatagaagg
      481 tgtcgatgat caaaaagaat acgaagcaag aattgatgct caaaatgaaa aaatggagac
      541 agagaatcca gaaactctag atcgagatga acaaaatggt caaaagaaaa aagaagatgg
      601 tctggatgtt gataaattga tcacgattga ggaagcagca aaaatcgccg tcgacaaagt
      661 aggaagcggt acggcaacag attgggattt ggataaagat ttaggtacta cttattggga
      721 agtcaaagta aaagacggca atcaaagtac atcagtcaag atcaatagcc aaacaggcga
      781 agtactgtca actgaacaag atgattaaga atttcttcgg aaaacaagag ttgatttttc
      841 ttttagtcat gatacactag acaaaataac ttgtttgaag gagcgattta cttgagttta
      901 gaaacgacct ttgccaatca tatctttgcc aatcctttga tgaatgcatc tggtgtccac
      961 tgcatgacta cccaggaatt agatgaactg gctcattcag aagcaggagc atttatcact
     1021 aagagctgta cgatcaatga acgaaaagga aatcccgaac cacgctattt tgatgttcct
     1081 ttagggagta tcaattctat gggacttcca aacttaggtt tttcttatta tctagagtat
     1141 gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac cgttattttt ttccattgcc
     1201 gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa tagaaaaaag tgggtttaat
     1261 gggatcactg aattaaattt atcttgtccc aatgtgcctg gaaaaccaca actagcttac
     1321 gattttgagg ccacttatga aacactgaaa gaagtattca gcatcttttc taagccgcta
     1381 ggaatcaaat tgcctcctta ttttgatttt gctcattttg atcagatggc tgatatcttg
     1441 aatcagtttc cattgaccta tgtcaatgct atcaacagtg tgggcaatgg tttgtatatc
     1501 gatacagaac aagaagcagt agtcatcaaa ccaaaagaag ggttcggcgg cattggcgga
     1561 gagtatatca agccgactgc tttggcgaat gttcgcgctt tttatacacg tttgaaacca
     1621 gaaatccaaa tcattggtac aggtgggatt cggacaggac aagatgcatt tgaacatctg
     1681 ctatgtggcg caagcatgtt acagattggt accgagcttc ataaagaagg gccggaaatt
     1741 ttttctagaa tcataaaaga attaacgcag attatgtcag aaaaaggata tacgtcaatt
     1801 gacgaattta aaggcaaatt acgcaccatt tcatagcaaa gagacgaagg tcatgattga
     1861 tcttcgtctt tttttataaa aaacactcgt ctgttcattc ctgtgcaagc gtactcattg
     1921 tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa ggaggataat atgaatgatg
     1981 caacagaatt agcaaaagag cttaaagaaa aagaatttag ttttcaagaa ctagttacgg
     2041 atatacagaa aaaaataaag aagcaaaatc atgaattgaa tgcgtttgtc gcgcttgaac
     2101 cattcgagag taattcccac gagctattga ttccccagtc agaaaaaggg ccattggctg
     2161 gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa gggatggcta gctacttcag
     2221 gatctcgttt atttgaaaca caccgagctt ctcatacatc taattatgtg cggcaagcag
     2281 aagcgatagg tctagttcct tttggacaaa ccaatgcgcc agagtttggt ttcaaaaata
     2341 ttacagaccc agtcatctat ggcccagcaa gaaacccttg gaaccttgaa tgtacaccgg
     2401 gcggatcaag tggaggagct gctgctgcag tttcatcagg aatcgttcct ttagctggtg
     2461 ctagtgatgg cggtggttct attagaatac ccgcttcgtt ttgcggattg attgggctga
     2521 aaccttcgcg agggacgatg ccagttggtc catatgcttg gagaggatgg caaggagctg
     2581 ctattgattt cggcttgaca gtttctatga gagacacgga ggctttattt tatgggatga
     2641 gaagtatcca ttccggtgcg ccatatcaag tatcgccagt tgagtggcaa acacatccaa
     2701 gaaaaaaacg gttgaagata gctttttgtg ttgattcacc gatccactca cagattagtg
     2761 aagaggcagt acttgctgta aaaaaagctg tagatttcct tggaaaagaa gggcatgatt
     2821 tgacagagat tccttaccca ctagatggtc gtaaactgat cacgtcttat tatcagatga
     2881 atggcgcaga aacagcagca atgatccgct cgattgaaac aggcatccag cgagctgtca
     2941 gaaaagaaga acttgaaccc atttcttgga ctttgttcca atatggtcag aagctctctg
     3001 ccgctactta catcgattct ctgcatgtat gggatgaagc agcaattgtc atggaaaacc
     3061 tacatcaaga atacgatcta ttcctttcac caacgactgc atttaccgcc cctaaaatca
     3121 gcgaagattt gcaaagtgat gcgataagag cacagatgga acacatcagt gattgttctg
     3181 aagtagaagg tttagacgtt gtttcttcca tgtttgagga gagcttgaag atcacacctt
     3241 atacacagtt ggctaatctg actggacaac cagcaatcag cttgcctact catttgacaa
     3301 aagaaaacat gcctctagga atccaattta tggctgccag aggaagagaa gatttgctat
     3361 ttcaaatcgg ctatctattt gaagcaaatc atcagttcca tttaccaaat ccatggaaat
     3421 agcagaaaca aggagaagaa gaatgaagaa aaaaagattg tttgctctaa taactagtgc
     3481 cttttttatt ttaagcgctt gcggtacagc tgccgctaat caggaagata acagctggag
     3541 taatgtagaa aaaaagaaag aattagtagt agcgacttct ggcacactgt ttcccgcatc
     3601 ttattataat gatcaaaatg aattagttgg ttatgatgta gatttggcaa aagaggtggc
     3661 taaacggtta aatgtcaaaa tctcctttaa agaatacaac gtggatggac aaatcacttc
     3721 tgtttcaaaa agagaatcag attttgctgc gaacgatttt ggtatcacaa aagaaagaga
     3781 aaaaaaattc tccctttcag agactttcaa atattcattt gacagtatga tcgtacgaaa
     3841 aaaagatgat tcaggaatcc actcacttga agatcttaaa gggaaaaaag cagctggcga
     3901 acccaatact agctatatgc gtttagcgga aaaacacgga gctaaattag tcacatatga
     3961 caatgccacg aatgatcagt atttaagcga tgtagcaaat ggtcgaacag atgttattct
     4021 aaatgattat tatctgcaga aaatggccgt atctgcttta ccagatatcc ctgtaaaaat
     4081 actggagaac gtttatttca atgaaaacga aagtggtttt ttattgaaag aaggaaatga
     4141 tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg aaagaagatg ggacgacaaa
     4201 gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc aaaccgaaag aaacgatggc
     4261 tgagtcggtg agtgagtgat gtactttcct ctaattgatt tttccctcat gtggacttca
     4321 cttcctttcg tactgcaagg cttggtatac acattaggga ttggcttcgt gtcgtttctt
     4381 ttaggaaatc tggtagggtt gcttttgaca gttttaggtc ttttgaattg gctgcctctg
     4441 aatgtattta ttcgttttta tttatcgttc tttagaggca ttcccgcact agtcctgctg
     4501 tttctgttat attttgggtt accttatcaa ttaagtgcct taacggcttc agtcatctgc
     4561 tttacgatta ccagcagtgc atttattggt gaaatctatc gaggatcact agcaggcgtt
     4621 tcttcaggtc agtgggacgc tggtttagct tctggttttt ctttctttgg ggtattgaaa
     4681 tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg cactcagtaa cgtagctatg
     4741 gatctagtga aaggtacttc gttagcagca acaatcacag tgccagaaat atttcaaaaa
     4801 gcaaagatca taggcggtcg gacattcgat tatttttctc tctatatttt agttgcactg
     4861 atttattggg tcatttgtat cgggatcgaa aaagtgcaac agtatttaga aaaacgttct
     4921 atgcatcagt caatctgaaa aatagaaatg gtgctagcgt ggctggcacc atttctattt
     4981 tttgtttctt gtatattctg cctagtattt taaaaccatt tcatgtaaaa tgtaaatcga
     5041 aaatatgttc ggaggtagaa aacatgaaga ccccgctaac catcgaaata gaatcctcgt
     5101 tataccaata ttgcatcgag caaggcggct tggttgtaga agaagtcacg atgcctgatg
     5161 accaaggaat tgtagatacg cttagctgct tgacaaaatt tgatggaagc cgagaatggc
     5221 gatgctatga gctgaaagtg acaaaagcag attttcgctc tacagccaaa ctgtcatttg
     5281 ttggacatta taattatttt gttttaccaa gtaaactata tgaagaagta aaaactgaaa
     5341 tccctacagg aataggtgtt ttagtgtatc gtccgtacac ggttgaagag gagatgcctg
     5401 cctctggtac atttctgatt gcgaaaaaag cagcaaagaa agagcttgct gtaccggaag
     5461 aagctttgac aaaccgcttc atggcttctt tattcaggga agtaagaaaa gcaaagcaaa
     5521 tggagcgagg cgtaaaatat tttccaacag atcaattgta caaagaattg aaaagacgtt
     5581 cagaaaatca agatccattt tctaacgaac gatattatga acggttttta gaggaaatag
     5641 ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc gcttcagcat gattatgaat
     5701 atttgaggca acaacagcag atccgtcggt tgcctacaga gccattggag tgaaaaatat
     5761 gtactatcct tatttaagag gaaaacaatt tgacctatta gcattaaaag aagcactgtc
     5821 gcgaggattg ctctccaata aaatccaacc agtgatcgaa ccagtacgtg attccgctac
     5881 gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat cgaatcgctg tgatccaaaa
     5941 tccccaagta ggacaattca aattattcga tcagcatgtg cacagttgga cagtcaaaga
     6001 aaatagctct gtcgtccctg cacagatctt aacgccagaa aatctcagtg aagtactgga
     6061 ttcacctcca gcgtttcttg ttttcgatgg acagcactac ccaaaagata cagaggtgtg
     6121 gaaacagttg gcaggagttg attcgaaatt tttgatacca gatactagtc gctttcgcat
     6181 ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt caaacgagaa agcatgttga
     6241 aagttatgca gataaaacag atgacttttt tagtgatgac tatctttttt tccacgcaga
     6301 cggatatatt ggattttctg atttcacgat cgaaggtagc cgttatttcg ataaagggtt
     6361 ccctagccga gcgcttgcta tccatctaac gtatattgat gcttacggca atatacgcgt
     6421 gaaacatttt gtctctgaca gtaacgactc tgctaaagac caagcattga agtttcttga
     6481 agcaggagat aaaatgaaaa aatggatcat gcgtcaccat catcaactct tgattacttc
     6541 aggaatgatt gaattattgg ctctttacca gcaacaaaaa ttccctggac tgggagtgtt
     6601 gaaaaagtgg tcacttatgc atcatttgga acttattagt cacctgctag atcatccaaa
     6661 agattggctt aaatattatt caaaagttca ggaactatat gaagtgatcc aatgattaga
     6721 taatgtaaat gaaaaaggaa tagaaaagag gaaactggat gtatattcgg caaacaagga
     6781 aagaagaagt agaagaagtg gtagaaatca ttaatgccgc agcggatttc attgcttcgc
     6841 aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa agaaacgatt ttgaacgata
     6901 ttgaaagaaa agaaagctat gtattaatag tggaagatca aattgctgga acagctgcat
     6961 tagtctcaag cgtggatccc gtttacacaa aaatagatgg tagttggaaa gaatcaactg
     7021 gtccttattt atcgattcat cgtgtcgctt tagcagaaag tactcgagga aaaaaactag
     7081 caaaaccgtt cttagaacat ttgttgacga ttgcagccag caaaaatatc caagatatcc
     7141 gtatcgatac ttatccagct aatgaaccga tggaaaagac catctattct gctggattca
     7201 cttatcaagg gatgattgaa tttccttttg aacacggcga aagaaaagca tatcaaataa
     7261 tcatcaattg actataaaat catctgagca aagataaaga cattaacact actgaaaaaa
     7321 acaatcatat gatagccaag aggttgtaac agaagtggcc agcttcaaaa aacaagaaag
     7381 aatttccgaa aatgcttctc aaatttttgt ggaattttag cgtattttac gaaatagctg
     7441 ctttctgaaa ctcccttcat cgagaggtcg tgacatagct tttgtcacga cctctcggct
     7501 tatcctacga gtattattcg atacatttat atcaataatc ctttttttat tttatctgca
     7561 gcttcttgga acgctccatc gtttgacacg actaaaagtg aggggatagc tttcaaacgt
     7621 ttcaactgtg ctaaatcttc tacataaacc gccagtctgg ctgaaatctg ttcagatgaa
     7681 tctccacgtt ttttcaggcg cgattgcaat gtttctttag agatcgtaat aaagatagga
     7741 cggactaccg tcccgaaata ctcatataaa tgccaaaaac catttgctgt caaaacggcg
     7801 taacaatttc ctactgtcag tttcttttta atttctgctt tactggaacc atatttatgt
     7861 tgagcatatt ggtcccactc tgcaaactca tttcccttga tcatctgatt gaatgtattg
     7921 tcagaaacaa aataataatc ctcttgatct ttttccccag gtcttggtga tcgattcgtg
     7981 taagtaatga tcttttgttc cggctgaaaa atagcttctg cgagtgaagt ttttccagaa
     8041 ccagaaggac cgataaatac atagcaataa ttcattgtca tttctccttt gatgattgaa
     8101 caagtgaaaa agctttggaa aatatttcca aagcttttaa aagtaacttt gcttttttgt
     8161 atattatacc agcaagccag tcacaatagc acttaaaaag ctgactaaag tcgctgttag
     8221 caaaattttc aatccgtgtt ttgcgacaag atttcctttt tcttcattta atcccttcat
     8281 cgcaccagaa atgatcccga tagaagagaa gttggcaaat gaaacgagga agacagatat
     8341 aattgctgtt gtacgctcag taaaatggaa attaccattt gctaattctg tcatagcaac
     8401 aaattcattt gtaaccagtt tagtcgccat gatactaccg gcatccactg cttctttcca
     8461 tgggattccg ctgatgaagg caagaggggc aaagatgtaa cctaggatct cttggaaagt
     8521 gatgccgaat atcccgtgga agatagcatt gatcatggca atcaaagcaa caaaaccgat
     8581 aagcatagca gcaaccgtga tcgccacatg gaaaccatca agaatgtatt ctcccaacat
     8641 ttggaaaaat gtctgttctt tgttttcttc aatgatcagc tcatcttctt tttcttctaa
     8701 tacataggga tttacaattg aagccagaat ataaccgcca aataagttca aaacaagggc
     8761 agtgatcaca tatttagaat cgatcagtgc catataagat ccgacgatcg acatagaaac
     8821 tgtagacata gccgatacac tcatggtgaa caaacgtttc tcagatagga agggtaattc
     8881 cttttttatg gaaataaaaa cttccgattg tcctaaaata gcagaagcta ctccattata
     8941 agattccaat ttgcccatcc cgttgatttt acttaatcct agaccaacag ctttcataaa
     9001 taatggaaga atcttgatat agcgtagaat accgataata gcagaaataa atacaattgg
     9061 catcaatacg gaaagaaaga aaggtgcact tcctttattt gctacaccgg caaaaacaaa
     9121 gtcaacacct tgcccagcaa aagcaagaag atgatcaaac atttttgcca atacagaaac
     9181 aaccgctgta ccaaaagttg tacgtaataa tacgaaacca agaacaagct gtaaaacgaa
     9241 catcacaatt agtggtttca atttgattgc ttttttgtta ctgctgatca aaaaagcaag
     9301 ccctaatgtg acaaataaac caataatacc taataaataa ctcaaataat cactcctatt
     9361 ccaaattccg ttttatttta cctgttttgc aaataaaata ctaatcttta gtgaaatttt
     9421 cattactttt ttagagtgaa acgcattcat tttccattag aaaataaagc gaacaaaata
     9481 aaaggtttaa aaagtgtaac gtcttagtaa agtctataaa aaaacgaaac tatcgattaa
     9541 gctaatagtt tcgttttcaa catttataag taaacttttt ctattggtaa tatagatttt
     9601 cggaagggta gacaggtgcg caggtaatat cgattcctag ttttttcaat gtttgttcat
     9661 catttttatt gaccatcaca gtagagtggg cttgtgctcc ctcaagttca gctagtttat
     9721 cataagcaac ttgagcgatt ggattcgtta ctgcactgat tgataaagcg atcaagactt
     9781 cattgatgct tagtgcatcc aaagaggaat gaagtgtctt tgatttcaat ccttgtattg
     9841 tttcaagaac taatggtgac aataaaggaa tgtcatctgc gatatgggct aaatgtttta
     9901 ctgcatttaa gataactgcc gctgacgcat ccatcaatga acttgtacgc ccggtaatga
     9961 tgacttcatc tggtaattcg attgcaatca cagcagaagg atcttttgta ggactttgcg
    10021 cttgaatctt atctgcatag tcatgggcag ggactaccac gtttcggtct tcaggacgta
    10081 aaccgacttc ttccataatc agtttgattc gattaactgc ttcttcgtcg atcaatcctt
    10141 ttttgaagtc gcattctgtt tggaaataac gacggatgat ttcttgttta gaggcttctt
    10201 ggacaacggt atcatccacg atcccaaatc ctacacgatt cacacccatg tcagtaggag
    10261 attgataaac agattcttta ccagtaattt tttcaataat acgtttgatt acaggaaatg
    10321 tctcaacatc ccgattatag ttcacagcta ctttattgta ggcatcaaag tggaaggaat
    10381 cgatcatatt gacatctttt agatcgactg tggctgcttc ataagcaatg ttcagcggat
    10441 gtttcaacgg aacattccat actgggaaag tttcgaactt ggagtaacca gctgcatgtc
    10501 ctttttggct ttcatgatac agttggttca aggaagtagc gagctttcca cttcctgggc
    10561 caggagctgt cactacaacg attggtttag ttgtttcaat atactcattt tttccaaaac
    10621 catcttctga gacgattttt tctacgttga ctggatagtc ttcgatttct gagtgtttat
    10681 agaccttgat gtttcgtctt tctagtttat tgataaagac tttcgtggca ggctgtccac
    10741 tatagcgagt gataacgaca ctgttgatta ataagccata accacgtaat tcatcgatta
    10801 accgcaagat atccatatca taagtaatcc cataatcacc acggatctta ttacgttcaa
    10861 tatctccagc atagacgcaa atcagtattt cagcttgatc tttcaatttt tgcagcaatt
    10921 tgattttcgc atcttcttca aatcctggaa gtacacgttt cgcatgcttg tcgtcaacta
    10981 gcttcccacc aaattctaaa tataatttgt catagtggtt cactcgttcc aaaatatacg
    11041 ctgactgctc ttcaatatat ttttctgaat caaaaccaat ttttttcact aggttccctc
    11101 cttaagtact aaagcatttt ttcatttttt tgaggattcg tcaactggaa gagcgaaatt
    11161 cctcaaaaaa acaaagaaaa tggtttaaac caacttgtct agatagttat tcattggtat
    11221 gatagttttt gataaggaag gtgctacatg aaaaaaagac agaaaaagaa aaacgcatat
    11281 aaacactata tccgttcgat ttttaccggt tatgaaagaa tgcttgaaga tcccgaattg
    11341 gaacaattga cgtttactta tctaaacgaa gaaacgcagc taactcgtga tgagcatcag
    11401 cgcattcatt tcacaacaag agatctgcct agtaaataaa aaataagata aaggtcatcg
    11461 gattcgattc tgtcctatca gatggaaaga ctagttgatc gaaaaaaagg ctgtaccaaa
    11521 ttttggtgca gcctgtttta tggagcattg cccgctcttt tttataacaa ttttttacag
    11581 aaaatggtac tattgaagta ttaataagtg aaaaacagat gagtaagagg aggcaagtag
    11641 tatgaaagag ccagatacaa atgcaaatta tgagccagac gaactagagg agacgaatgc
    11701 ggatcaggat acaggacaag aatcgtcttc tttttacgat atcaaagaaa aagcaagcat
    11761 gaatctttcc caattattag aagacttaca ggcttttgaa aaagctgtcc gcgaagaaga
    11821 tatccctgag atctaccgtt tatacaatgg ccgattgaat gaagaattaa aaagaagctc
    11881 aaatgaaaat cacgagatcg atcaattgct gatgcgtaag atccatgatc gttttttaca
    11941 ggaatttcct tttatggaac aagtagaaaa catctcgcca acgatgagct attacaaaat
    12001 cggcacttat taccatgatc ggcccacggt cggtattgat gcaagtctgc cagaaatttt
    12061 tgttttgcct aagatcgatg aagagtggga gaaatattcc caaccggagt caacggacta
    12121 tgacaaaaaa atcaatgagc tagacgcaaa ggtgatcact gctcagacag aaattgaacg
    12181 tttagatgaa caaataaaag aaatcaatcg acaaatgact gatttgaacg acaataaagg
    12241 attcttgaat cgtaaaaaaa tcgaggaaga aattcaagaa ttagagaaga agaagcaagt
    12301 actatctaat gaaaaattag gctggcttcc ttatattgag acgcctgaaa caatccagca
    12361 gcaaaaagaa gcattgaagc aagaagcaag agcagaccag cttcgtgcag ccatcgtaga
    12421 aaaagaacaa aggcaaatca gacgctattt cggtagcaaa gagggattcg gtcaagcaat
    12481 ccatgaattc ttgatgaatt atcttggcaa tgagaatcct aataatcaat ctaatgaagg
    12541 aggttccgag tatgaatgaa cacgatgaag cagaatggac aaaaaatgaa gaacaaacag
    12601 aagatcatga agaaacgaac acttcattgg aagaacaaac aagtaatcct ctggatgaca
    12661 cagaagaaat ccctatgcta gaggaaacaa aaatacacga aaaagaaaaa gtaactccga
    12721 cgaatacgaa tactgcagaa aacacccatg cttacgaaat aactgaaaat cccgggtatt
    12781 tagaaggaaa agagcaagat catcaagata tcgtcagttt gattgaaaca gcggaagcag
    12841 aattagcgga tttacgtatg agaaaagatt tgatcgaatc agattttcca caattattag
    12901 aatcatatga tcgttttata ttgaatgaag aaccaatctc cacgatcgga aagacaagcc
    12961 tgatcgaata cttcacgtat gaattactga aaccgttgaa tgatattggt ctggaacggt
    13021 caaattcagc ttatgacaca tggaaaacaa gacatttttc gatcaattat acgttgaatg
    13081 gacaaaacga attagtcttt tcctttgtat taccgaccat cgatcaacga taccaagtgg
    13141 aatcgatgag tctcctaaac gtatcaccag agacaatgga aatcaatgtc caagatgacc
    13201 gggtgctttc tttgatccga cactggtcag tggatcgagt attctctgca gggcagatca
    13261 cgatattcaa tcacaaattg aatcaattat tagcccatgc aagaacactt ggttttaccg
    13321 ttaatcagac attactagac aatacgaagc cacttcgttt gaatcttcag agcgaatttg
    13381 aattgacgaa tgaagtattg gatgatattt ttatcgtggc aatgaaaaat ccatcctacg
    13441 atatggaaaa gatcaacgaa actacttatc aagtacgatt agataaagga cagtctttaa
    13501 cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat ctcatctgga gactacccac
    13561 gatctgtcat tgatttcttt atcaattacg aattcttggt cccattaatg gtgagaaagt
    13621 cctgattgga taagttggat taccagatgt cattcagata attctgttcc aaaggacttg
    13681 cggcagttat ccagaataat tgtcacaagt cttttctgta tgtactaaat ggacgtgaat
    13741 aacttgctga tgaaggaggg atttcattag gaatgtccac aaataaaata gcacagctta
    13801 gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt tcaatttatt ccgaatttcc
    13861 agccaatgac tgctattttt ttatttatag tactttactt aagcttaaaa gatgcgttaa
    13921 ttgtcatgag tctttctatt gcgatcagca gtttttattt tggtgttgga ccatgggtca
    13981 tcggccaatg gatcagctat actgttgttc tgagtttgtt ttcaatcgtc tgcttgagaa
    14041 aaacagtgca aaggaatcta tggttaaagg gagtctgttt ttttctggcg ggcatggttt
    14101 acggaatagg tatgaccgtt tttgatacgc tgttatatcg tttgcctcaa ccttggatct
    14161 attaccttca aggggtgtcg tttgatttga tgcacagtat aggcaatgtt gtgttctttc
    14221 ttgtttttct gccagtcgtc aaacgttttt acaatcattc aggaggaaaa aatgaaaaaa
    14281 ataatttata gtttgcttgc aatgagtgtc agtatactca ttttgacaag ttgcagtaca
    14341 acctatacac aatcggcttc caaccaaaag gaggaagtaa aaacatcgca aaaagcaaca
    14401 atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag aagtgttctt caaaaaaggc
    14461 gatgatttac tgagtatttt gaaacgaaat tttgaagtca aagaagataa cggcttcatc
    14521 acttcgcttg aagggcactc acaggatgag aaaaatcaac tctattggat gtttactgtg
    14581 gacgggaaaa gtgctactac tggtgccaaa gagatcaaat tgaatgatgg acaatcggtc
    14641 attttcaatt tgtctaaact ataagtttca taaaaaactg ttaaagggcg aatattgcca
    14701 taattcagtg agttcagttg atgaaagaag gaaaataaca tggaaaattt taaaaaaagc
    14761 ggaatgtttt ccgtaattgc tgctctaggg gctaatattc tagttgctat cagcaaattt
    14821 gtcggctatg caatcagtgg cagtgccgcc atgctaaacg aaagcatcca cagtatcgtt
    14881 gattgcagca atcagatttt gctgttattc ggtgataaac aagccaataa aggacagagc
    14941 gagttgcatc aatttggtga aggacgagca aaatactttt tcagtacaat cgtcgcaatg
    15001 atgcttttct tcggcggtgg ggcacttggg gtgatggaag cttttgaaaa gttgacgcat
    15061 ccatcccatg aagtgggtaa tccgatcatt gttatagcaa tactgttatt tggtttggta
    15121 atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca aagaattgaa tactgaaaaa
    15181 ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg aaatactgat tatttttacg
    15241 gaagacttgt gtgctgtaat cggtttggtc ttggctttag caggaacaat attgacttat
    15301 gcaaccggga ttgctgcatt tgatgcgatc agcggattgc tgatcggttt cttgctgatg
    15361 ggagccgcca ttttcctagc aaaagaattt tatagtctga tcatcggtga aagcgtgaca
    15421 gcaagcgatt tatcaaaaat caagttagct tttgaacgtc ctgagatcag tcggctgatc
    15481 gatataaaaa cagttcattt aagtccaacg gagattttag ttgcagcaaa agcagatatc
    15541 gttggtaaca aagagaatga agcttactcg gtcatcaatg atattgaaaa aaatatgcgt
    15601 cagtctcttc ctgacaagaa gatgtatata tacattgaaa cagataaata tgacccaaat
    15661 tattctcgta aataaaacgt ttattcatga attgaagcaa aaatgagaaa aatataatct
    15721 tgtttttaaa taaaacggct acaatttagc gaatttatgt tacaatgagt ccgctgttta
    15781 tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga aaagtgcgcc atggcttcaa
    15841 gctttgcatg cagtgatgcc actttgtata agctatatac cagtaggatt agcttgcgga
    15901 gtattgttgc aaaaagttgg atttgatcct ctcttatcag gactgttatc gattctggtc
    15961 ttttccggtg gcgcgcagtt tttagttgca tctatgctta cgacgcaagc atcatttgca
    16021 acgacattat tgatggtttt ctttttagaa ttacgctata cattattagg agcaagtctt
    16081 gccggtttta tgaaaaaaga aaagcggacg tttttggctg tcttttctca atcactgaat
    16141 gatgaaaact atgcggtgaa ctacttaaag ttttcaactg acccttcctg gaataaaaga
    16201 aaggctttat atgtcaattg gttctcaatg actgcatggg ccggtagcaa tatgatcggt
    16261 aattttttcg gctcggtgat tcgagtagat gctgaccttg tccattttgc tttgacggcc
    16321 atgttcattt tcatgtttat catgcagatg aaaagcgcac tactgatctt tacaggttta
    16381 ttctcaggcg tattaggggt cgtattcatg gtattattcc aaaatacttt cggattgatt
    16441 gcagcaacag tcattgcttc atttgccgga tttatgctgg agaaggcatt caaaaaagaa
    16501 aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg agccgctctt caacttcccg
    16561 gaacaggagg ccaatcacca tgactaaact atatttgcta cttttagttg cttgtctgtt
    16621 catcgtggca tatatcccgc gcttgttccc gatgctttat tttactcatc gaaaagtgcc
    16681 atcctggttc agtgactgga tgaaatatgt accggtggca ttatttgcgg cgttagcttt
    16741 taaagatgtt ttcattactc atgaacatct ggatattgct tggaatatca aaatagctgc
    16801 aatgattcta gtagcaggcg tggcttacaa aacacgttcg atggcgttgt cagttttgac
    16861 aggacttgcg tctgtctttt tgctgtctat gctttaaact gttttatttt attaaaaaca
    16921 gagattgcga cataagttgt tcaaactgat ctatccgaac tgcatttgca acagtcaatt
    16981 ctggatgcaa gtttattcgt agggataaaa aagattagtg ttggcttatg atgcaagctc
    17041 ttttttattt taggaattag agagggattt gtccttctat gattttttgc tataataggg
    17101 aagatgttta ttttatgaaa gaatagttga gggaatttaa atgaataaaa aattgatgca
    17161 aggaacattt tggctaacct ttgctaatct tctatgtaaa gttttagggg tagtctattt
    17221 gattccctgg ctaagtatga tggggaacaa tcaagatggt atgcttgcta cgacattgta
    17281 taatgttggc tatcttcctt atggattgtt cctgatgctt ggtacagtcg gatttccaaa
    17341 tgcgattgca aaaaaagtag ctgtagccac aaaagaagga gataacgctg cttgtcggct
    17401 gatttttaga agtacgatca atatcatgtt tgtcatcggt atcgcctctg ctgcactgat
    17461 gtatttattt gctcctttac tagccggaat cagtccgatt gctaacgtta ataatgggat
    17521 actagctatc agaagtttat gcccatcttt gattgctatc ccaattctta gtgcaatgag
    17581 aggatatttc caaggaaaaa atgatctgcg gccttatgga acttctttga ttatcgaaca
    17641 ggctgtgcga gtgatcgtta tcttggctgg tacttattac ttgcgcgtat tgactgacgg
    17701 aaccatatta gaagctgtat tgatcagtac agtcgcttct ttcttcggtg ggttagctgc
    17761 gattatccat atgtatatcg tcggacgcag aaaagacttc ttcgaactta aagatttttt
    17821 gatttccagc cgttatttcg aaagagaaaa ccgatctgcc tctgtctcta tcattcggga
    17881 aacactaccg tttatttttg tcggctcagt cattactatc gttcaaatga tcgaccaagt
    17941 aacgatgaaa ccactgcttc actttttccg tccagagatc gcagatcagc aactggaatt
    18001 cttattcagc cgtgcttctg tcaatccaaa taaattgaca ttgatcctga tctccatggt
    18061 aggaacagta gctataagca gcttgccaat attaagcacg atgaagaaaa aagatcggat
    18121 acaaatcgaa aaaacagtag gagatagttt ttcgattgcg ttattgattc ttcttccttc
    18181 attgactgga atgtctttat tagctggacc actatacaca ttgttttttg gctatgatcc
    18241 tgaaagtgtc ggatatttcc aaatggcttt gctagcttct ttgtttttct ctttattcac
    18301 gatcctatct acgatgcttc aatctttgaa tcaccatcgt tttgcgatcc gattaactgt
    18361 agaagcaatt atcctgaaag tcatcttcca agtaatcgga ttaggattag ttggcggata
    18421 cgggatgagc ttatcaaatg gcttagcatt cggtattgtc tttgttcgcg gctatcactt
    18481 tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc agcaattttt tcttaaaaac
    18541 tttccgctcc accctgatta tgcttgcagt atgttttgcc gttttctttt tgctgaatca
    18601 gcgattgtca atggaatcaa aaagctatgc aatgatttat tgtgtggctg taggaagtat
    18661 tggcggctta gtatttttat tttctcaatt cggaaaaaat gggtttcgaa tgttgaaaaa
    18721 tgttaaacat catagcagaa gcaaagaata ggttaactaa tcgttttttg ctgtcacttg
    18781 aaaaacggca actcgtatga ttacgcttgt cgtttttcta ttttccaatt ttagtttcat
    18841 atctaatctt acttatgata tagttataag gtctggaaaa attctttgaa acgaggaaat
    18901 taaacacatg aaacttgcag tagttacaga tagttcggca tatctgccgg aacgtatcaa
    18961 gaaccatccc gacttattcg ttattccaat ccctttgatt atggatggga aaatttataa
    19021 cgaaggaatc gatatcgaag cggatgaata ttatggactt ttaaaaaaca gtaaagattt
    19081 tcctactact tcacaacctg tcgtagggga agttttgggt ttatatgagg aattgaaaga
    19141 gaaagggtat gacacgattt taagtatcca tctttcttca gggatttctg gctttgtcaa
    19201 cacattattt gcgatgaaag atgacatcag cggagtaacg gtcattcctt atgactctaa
    19261 gatcactagt atgccgatgg gacacatggt agaagctgcc ttagacttaa atgatgaagg
    19321 tcagtccctt gatgaaatac ttgcacatat cgatcgaatc cgagataata cctacgctta
    19381 tctgattgta gatgatttga acaatttagt acgaggagga cgtttgacaa atggtgcagc
    19441 gctgattggc agcttattaa aaatcaaacc gatcctgaca ttttctgaag ggaaaattgt
    19501 tttattcgaa aaaatccgtt caagtaaaaa agcatttgct cgagctgaag aaattattgg
    19561 tagaagaaat aacgaaatac aaccgccagt caaactttac gtgatacatg caaataattt
    19621 agaagtagcg attgcggaga aagagaaatt gcagaaaaaa tatccaaatg cagaaatcga
    19681 aattggtcat ttcggaccag tcattggtac acatttaggt gaaaaagcca tcggcattgc
    19741 catttcagcg caataattcc ttttattcaa aaaacatacc aaaaatattc caacatcatc
    19801 ttggactttc tacatgttac taatgagcgt gtaaaagaac gagatggtgt ttttatttct
    19861 atcaatgaag ctctttttct ttgcaatcct cacttcaatc ctctataatg tcgcatatag
    19921 tttagtaaat gagtaaacta ctaatttact tatttactaa aaataaaagg atgaggagtt
    19981 aaaataatgg aaataccaac aaatttaaaa cataaaccag taatcgttgt agaagactat
    20041 gataaagttg atggaagaaa tgcattaaat acggatgcaa aagggctttc actgggcctt
    20101 gctcagtgga atgatcgtgg aaaagtcgat atctcaggca aggtatggcg acatactgga
    20161 gaaaaatggt cacgacagtc ggaagaatta ccaatcacac gtattttaga tttagcgatc
    20221 ttagctgcac aaggaagttt atacttccaa gatgcttatc gttatgaaaa attttatgat
    20281 ccagaaaatc cagtcgtaga catcattgga ttacaaggga accgaatgac ggtagaagta
    20341 gataccaaaa atccaaagat cgatgaagac atcattttgt attacgatac actacaaaaa
    20401 gacggagaac tgattgggga acgattccgt attttaaaac gtcttttaga tgagctagga
    20461 tattaataga cagagatgat caaaagggga agagaagcat ggagaatttc tcactaacag
    20521 aaaaccgaac cttttcacgg ctagaaaagc aaatgatctg gaagaaaccg aaaagccatc
    20581 ggacaagtgc agaagaatgg cggatcgcct ccgaaatcaa agggaattgg caagatcctg
    20641 aaatgaaaat cagtaacgta cttttggaag gagatgccgg gtcggggaag acacaattag
    20701 ccaaagcact atctgctgat ctgcaacttc cctatacaaa agtgacctgt tttgcagata
    20761 tggacaaatc agatgttttc ggagccttat tacctgtagt agattctaat aaggaacaag
    20821 accaagaatt actagaagct atttaccaaa cagatacact tgaagctgta ctgacactga
    20881 tccagaacca ttacggcatt gatccttttt ctgctaaaga aaaattagca gagctagttc
    20941 aaaggatcga agctgattat ccagatgcaa tccattacag ctattaccct tctgaaatcg
    21001 ttcgagcgat tgaaaaagga tatttattag agattcaaga gccgactgtc atccgagatg
    21061 cctctgttct tgtggcactt aactcagcgc tcgaaccaaa tgggatgttg aatttaccga
    21121 caggaatcat tcgtcgccat ccagattgcg tcattgtgat cactacaaat cgaaattacc
    21181 aaggaaatcg cccattaaat gaatctttaa gagatcggat gcaacatgcg gaaaaaatgg
    21241 atcttcctgc cttagaagtc atggcagaac gtgcgatggc gaaaactatg atccaaaaac
    21301 aagaacttct cttaaagatg gcagagatta tccgtttgtt ggatgaaact gcaaaagcta
    21361 acgccatcaa aggtgtagca ggaatgcgtt cttattttta ttgggcaaat acctataagc
    21421 aaggacaaga tttactccag tcgatttatc caaaagtttt gtataaatta tccactgatt
    21481 cagatgaatt ggcaattctt gaacaagctt tgtctgacag tggattgcta ctggaacttc
    21541 aggacatatt gagaaaagaa aaatggggtc atcctcaatc tgagcataca aaaggaagaa
    21601 ccattagcgc cgaagaagca aatgaacgaa acatcactga aaatgctgaa gaaattctgc
    21661 gcttagatga aaagaaatcg ttgtctgctg aagaaccaaa tgagggagaa gagaaacaag
    21721 aagaaacaat agaaaaaaac gagattcctc ctcaaatgca aaaagaacgc agtagcgata
    21781 tcgaaggaaa aaatcaaaaa gaacaacaaa caggagatga ttctcaagaa atgtctgctt
    21841 ctgacatgga agcacatgat aaggaaatca agaagcaact gaataaagaa gcgcgacaaa
    21901 tcatgaagga aacgattcat gaaaaagaag gtctcatcgt tcaccgacca gctttccaag
    21961 gaaaaacgcc ggaagcacgt gagctacaca tgcaagtaat gccaatagta gaatcactta
    22021 gccggcaaat tttagagtta ctggataatg aacaaacaga gacgtaccaa aaaggaaaat
    22081 acgaaggtca gcggttcaat gcaagcaaag tagcatatgg tgatttgaga aattttgaca
    22141 aaaagaaccc gccacatgag caaccttctt tagcggtagc tgtacggatc gatgaatctg
    22201 ggtcaatgat acgggatgat cggatcgaag cggcaaaaaa agcagcgatt gccattgccg
    22261 aattttctaa gaaagtcgat atcccattgt tgatttacgg agatacagca gaccgttcgt
    22321 caagagaaaa gacttctttg ttttcttata aagaatttga agacggattt caatggttaa
    22381 atgaaaaatt agtcactatg aaaccaaggc aaaacaatcg tgatggtgct gcacttcgtt
    22441 tagcagcaga aaaattaaac agacaatccg caacaaccaa actgttgctt aatattagtg
    22501 acggtcagcc aaaagcgttg ccggattata caggcaaaaa agcaaaagaa gatatccagt
    22561 ctgttttgaa agaatatgaa cgtcaaggaa tcctatttgt ctccgcagct attggccaag
    22621 acaaagaaga aatcaagtcg atctacggtg aaagtcgttt tgtagatatt actgacttga
    22681 atgaatttcc caagcaaatg attcaactga ttgcccgcta tctatgataa aataaagctc
    22741 aacgaacgca cttagcagat tcgttgagct tttcgtttct agttaccggt aacaaggata
    22801 cttctaaaat agaatcggtt ataatcaaga gggaccgtta aaggagtgaa acgatatgat
    22861 acaagaacaa aaatggtgga aagaagcagt aggctatcaa atctatcctg ctagtttcaa
    22921 agatagcaat ggcgatggtc aaggagacat caatgggatc cgtgaaaaac ttaattattt
    22981 gaaagatctt ggtatcggct ttatctggat caatccgatc tatcaatctc catttgtcga
    23041 taatggttat gacgtaagtg actatcaaga tatagaagag agattcggaa cgatggaaga
    23101 ttttgattta ttgctaaaag aagcacatga attagggatc aaagtgatta tggatcttgt
    23161 catcaaccat agttcggatc agcatcaatg gtttgaagaa tcgaaaaaat ctaaagaaag
    23221 cccgtatcgc gattattaca tttgggtcga cggggtagat ggcaaagaac cgaataattg
    23281 gacatcgatt ttcggcggtt ctgcttggga gtattctcat gaaactggac agtattatct
    23341 gcatgttttt gcaaaagaac aaccagactt aaattgggaa agcgagaaat tgaaagaaga
    23401 actattcaat atgatccgat ggtggttgga taaagggata gatggatttc gtttagatgc
    23461 gatttctcat gtaaaaaaag atgaatattc agtaaaagcc acagagaacc ctttctcacc
    23521 ctttcaaaat gtctcaggaa tcgaagaaca tttgaccgat ttgaaacatg tttttgaaga
    23581 gtacgatatc atgactgtcg gagaagcaag tggtgtcact gcagaagaag gaccacaatg
    23641 ggtagggaaa gacggttatt tcgatatgat attcgaattt gatcatatcc atatctggca
    23701 gcaagaaaaa gaagggcaat tagatgtcct taaattgaaa cttgcattaa gcgcttggca
    23761 aacttcattg gatggtatcg gatggaacgc tttatatatg gaaaaccatg atgttcctcg
    23821 tgccgtttca gtgtttggag atactcgtcc cgatttttgg gctatgtctg caaaagcaat
    23881 cgctatgatg tatttctttt tgcaaggtac gccatttatt tatcaaggac aggaaatcgg
    23941 aatgacgaat atgccctttg aatcgatcga tcaagttgat gcagtagatt cgaaaagact
    24001 ttataaaagg ctgcttgcgg aaggtaagac aagagaagaa gcattggata tcattcgtga
    24061 aacaacgaga gacaacagca ggacacccat gcaatggact tcggaacaat atgctggttt
    24121 ttctacacat gaaccttggc tgatcactaa tccaaatacc aaaacgatca atgtagaaca
    24181 acaagaatat gaaccagagt cggtcctgca attctataag aacatgatcc gcattagaca
    24241 aaccaataaa ggtctgatat acggttctta taaagaatat cttcatgaac atccacaact
    24301 ttatgtctat gaaagatatt tagaagatga acaatatctt attatggtaa acttaacaga
    24361 atcacttgct gactatgaac ttccaaaaga agcagatcag tcctggacat tactcttgtc
    24421 aaattcctct agcggagaat ttgaagctaa aggcatacta gcaccttatg aagctcggtt
    24481 atataaaaca aacaagtaaa acttcctcgt taaagttcat tagttggact ttgcgaggaa
    24541 gtttttcaga ttgctctgtc aattactcat ttcaataatt cgctctagga ccaccgatat
    24601 atttaggacg agagcgaagg gctgtcacgt gagcttgtcc aagggttttc aaacgaggtc
    24661 tgacaggtac ttggacatgt ttgatatgca taccgattga tgtgtcaccg atatcgatac
    24721 cggcttgtcc aactacgtgt tccacttcga caggatcatt gaactggtca aaagcagcaa
    24781 cagaacaagc acctccagca tgtagtgcag gaacaacaga gacaatttcg aaattttttg
    24841 cttctgccac tgttcgttct actactaatg ctcggttcaa atgttcacaa ccttggacag
    24901 ctagcgcaat ttctttagga tccaacaact cttttaacgt acggatgatc cattgaccaa
    24961 cttccgcact ggaatttttt ccaatatgtc ctccaacgac ttcgcttgtg ctgcatccta
    25021 aaacaaaaag atcacctttt ttcaagtgtg cctcagccaa tatgtcatta actatttcag
    25081 tcaattggtc ttttaattct ttttctgaca acttcatttt ctaaaacctt ctttttcaat
    25141 taatattgct tccgtgcttg aatacgttga agacttgcag ttataggaaa ggcaagtccc
    25201 attccaatca gattttggaa gatgtttcct ggtatagaag ccactccagc cggccaatca
    25261 tataaaatcc aaccggcgat accatagccg atgatcataa ctaagcttcc taataaaagc
    25321 cctaatcccc acatacgagt agaagatttg ctgaaagaac cagcaacata tccttgtaac
    25381 ccgtggatca ctaatgaaaa aactgcccac tgcggatatc ctgaaatcaa atcgatcaat
    25441 agaccactgg aagcaccaac aactaatcca cccgttggac cataaagaaa agcagcggta
    25501 tagatcccgg cctcgcataa tgtcacaaat ccattcgtag ccggtacagg gatcaaaatt
    25561 gttaatgaaa gggcaactgt caacgcaatc agcatagcat agatcgttaa ttgcttagtt
    25621 ttcatttctc attcctcctt tttgaatacc gccagaccag acacttccgg tatgatcgtt
    25681 catcagcacg ccattagaaa tacaatgggc aacaaatttt ttactttctg ctactgcttt
    25741 ggtaaaatct gcccctaaca caagattcgc tgttattgca gaagaaaagg cacaaccggc
    25801 cccgtttact gttgtagtgt cgattttttt atgagaaaat acctcataat gatcaattga
    25861 atagagaaga tccacagctt catctccagc catccttgtg ccgcctttga tcacaatgtt
    25921 ttttgttcct gaagcagtga gttctttagc gagatggatc atttctgtta acgaagaggg
    25981 aagagcttga ccagaaagta aagcagcttc tgccaaatta ggcgtaatca tcgtaacaag
    26041 tggaaaaagt tcttcgatga gctgcgaaat atacaattga ttgatcacag cttcagtttc
    26101 tttgaatgcc aaaacagggt ctaaaatgat tgggatattt tgttttgttt ttatgaagtc
    26161 tcgaacaacc atgattgctt cacttgaatt caataaccca attttgatac catctaatga
    26221 agtcatttta tcaatcgaaa ctaactgtcg tttaagcaat tccaaagata tagattccag
    26281 cataaatcgc tcattaatat ctagtgcccc tatagaagtc aaggcgctta gtccgaatag
    26341 accaaaattc tcaaaagttt ttaaatctgt ttggattcct ccaccagcaa atggatcaga
    26401 accgccaatt gtcaagattc ttttcataac attttcctcc atgaataaga gtataacgaa
    26461 attttcaaaa aagaaaaaca gccaattggc atatttttat ctcatccaat ttaaaaaaac
    26521 aaaaagaaaa gaaagaccaa aatggatctt tctttcctta aatagttagg acttttgtga
    26581 ttttaattct ttctcgattt gaagccgttg cactttcatt gtagctgttc gcgggattgc
    26641 atcaaaatca cggatgatag ggacgttcaa gcgaggaagt tcatggactt gctcccacca
    26701 tcgattccaa tccatttctt tatcaggagc taaagcaata atcggttgtg gagaatgatt
    26761 tttatccctt acaatcacta cttctgccaa aaaatctaac gaatctaata aaaagtcttc
    26821 aatagctaat gtactattga tcgtttcgat caaatccact tgccgatctt tcaaaaatag
    26881 gtggccatgc ttatccataa aaccgtaatc tccgctatcc caccaatcgc cataaacatt
    26941 ttcctggaac cgtgcatctt ccttgtaata agtcaaagcc cgtcctttag acagtaattg
    27001 tatatgacca tctgtgtttt caggtaggac attcccaact gaatctgtaa tccgagcgct
    27061 tgtcatgtct tccagtccaa cgcccatatc tcttgcatca cttgttttca aactctctag
    27121 tgtatgagcc ttaagaatca ttggtccgca ttcactttgg ccatatactt gaagaaatac
    27181 cgcatcctgt gccatcgacg ttcgcaaaaa tgtcttcatt gtctggttgt ttatagcatc
    27241 aaaagtggag tgatagtatc ggatacccga aaaagcttct ggatgctcct tagcagtaaa
    27301 acgccactga acaaagttat tcggatgggt ctctagtgca attggccggt gagcttccaa
    27361 catatgaaca acttttgaac tttgtgcgtt tgctaaaggc atcataggaa atcccatgga
    27421 catcaaagaa gagataccaa tattgaatct ggaatgcact ggagagatgt gaaaagcgat
    27481 taatttcttt tccgaaattt ttgtgaaaac tgttttttgc catttcgtcc gccatcccat
    27541 agaatgagca gaatgacaaa taagtttagg gataccagtt gtaccagaag tatgggtcat
    27601 ataagaaatt tcatttttgt ctaaaaatga ttgagaaaca gacaaagcag gttgttccat
    27661 taaataaaga ataggaa
//
LOCUS       DACGDM010000028        25538 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.028, whole genome shotgun sequence.
ACCESSION   DACGDM010000028 DACGDM010000000
VERSION     DACGDM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.028"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            101..2161
                     /locus_tag="IXR05_001305"
     CDS             101..2161
                     /locus_tag="IXR05_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259842.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRREESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2244..2813
                     /locus_tag="IXR05_001306"
     CDS             2244..2813
                     /locus_tag="IXR05_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4259843.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(2988..3794)
                     /locus_tag="IXR05_001307"
     CDS             complement(2988..3794)
                     /locus_tag="IXR05_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259844.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3932..5446
                     /locus_tag="IXR05_001308"
     CDS             3932..5446
                     /locus_tag="IXR05_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAQ4259845.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5849..6832)
                     /locus_tag="IXR05_001309"
     CDS             complement(5849..6832)
                     /locus_tag="IXR05_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAQ4259846.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6837..7484)
                     /locus_tag="IXR05_001310"
     CDS             complement(6837..7484)
                     /locus_tag="IXR05_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4259847.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7569..8201)
                     /locus_tag="IXR05_001311"
     CDS             complement(7569..8201)
                     /locus_tag="IXR05_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4259848.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8217..8768)
                     /gene="coaC"
                     /locus_tag="IXR05_001312"
     CDS             complement(8217..8768)
                     /gene="coaC"
                     /locus_tag="IXR05_001312"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAQ4259849.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8765..9502)
                     /locus_tag="IXR05_001313"
     CDS             complement(8765..9502)
                     /locus_tag="IXR05_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAQ4259850.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9499..10488)
                     /locus_tag="IXR05_001314"
     CDS             complement(9499..10488)
                     /locus_tag="IXR05_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAQ4259851.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10746..11288
                     /locus_tag="IXR05_001315"
     CDS             10746..11288
                     /locus_tag="IXR05_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4259852.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11305..12390
                     /locus_tag="IXR05_001316"
     CDS             11305..12390
                     /locus_tag="IXR05_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259853.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12402..13208
                     /locus_tag="IXR05_001317"
     CDS             12402..13208
                     /locus_tag="IXR05_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259854.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13209..14036
                     /locus_tag="IXR05_001318"
     CDS             13209..14036
                     /locus_tag="IXR05_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4259855.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14033..15106
                     /locus_tag="IXR05_001319"
     CDS             14033..15106
                     /locus_tag="IXR05_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4259856.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15534..18230
                     /locus_tag="IXR05_001320"
     CDS             15534..18230
                     /locus_tag="IXR05_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4259857.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18307..18795
                     /locus_tag="IXR05_001321"
     CDS             18307..18795
                     /locus_tag="IXR05_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4259858.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18807..19301
                     /locus_tag="IXR05_001322"
     CDS             18807..19301
                     /locus_tag="IXR05_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4259859.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19322..20131
                     /locus_tag="IXR05_001323"
     CDS             19322..20131
                     /locus_tag="IXR05_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4259860.1"
                     /translation="MYDAFVVALAVFIGIAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20128..20949
                     /locus_tag="IXR05_001324"
     CDS             20128..20949
                     /locus_tag="IXR05_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4259861.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21000..23099
                     /locus_tag="IXR05_001325"
     CDS             21000..23099
                     /locus_tag="IXR05_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAQ4259862.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23096..24214
                     /locus_tag="IXR05_001326"
     CDS             23096..24214
                     /locus_tag="IXR05_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAQ4259863.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24253..25131
                     /locus_tag="IXR05_001327"
     CDS             24253..25131
                     /locus_tag="IXR05_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4259864.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25322..25474
                     /locus_tag="IXR05_001328"
     CDS             25322..25474
                     /locus_tag="IXR05_001328"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259865.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8061 a         4445 c         5414 g         7618 t
ORIGIN      
        1 cctaatagtc catcttcttt tgattttatt tatataatga aatcatctta tgaaaattac
       61 tacttcatgt ttagacaaga gtagggagga ctaagaataa atgtgttcaa aaagacgttc
      121 aaaacaacta aataaacacg cttgtcgttt agataaggaa cggtcgtgtt ctgaaaaaca
      181 ctacgttaag tttatgatgc gcacgatgct gatcagttta tctgtaggtg tctatatgca
      241 tgtacccgtt caggcaacga cacaaaccat caaggtcgta cgtacctctg tttctgagac
      301 cactgattcc cctatcacta ttactcatac tttcactgat gcaaatggaa aacagctact
      361 tcctgcattg acttcctata ataaagtcag ttatcctcca acgataaacc actactggtt
      421 aattcctaac aaaacattat ggacatcgga aaccggaagc agtgtgccgc tttctatctt
      481 ttccgatatg actgatccta caaaaggtga tcagttaaaa cagatcactg atattttgaa
      541 tcatgctttg acagatataa aggacggtgg aagcgcacaa gtttcttatg tatatgaaaa
      601 agattattca cagtttgaaa gaaagaaaat cgatgttctg gcagggacaa aagtttcgat
      661 atctgatctg gtagaaaggc tgaagaacgc agatggaaca caaggagata tgtccaaagt
      721 aatttcaaac aatgggaata tcgtggatac gactaataca ggaacatcta ctatttcctt
      781 gtcctatttt gatccaattg ctttaaaaac aatgactgca tctgctgtga tccatgttcg
      841 tgctgatcaa acagctatca aaggaaaaga tcttcactta agaacaggag agagttacgc
      901 ccctaaagat cttgttgaat atgtaacaaa aagcgatgga acttcaggaa ataaagaaga
      961 aatcaaaatg aacgggacag tagatactac aactccggga gaatatcccg ttgtattaac
     1021 ttatatagac tcgaaaacat caaatgtggc agaaacaaca gctgtagttt atgtagaagc
     1081 atctgctgct tcatcgactg tcatcactca ttttatagat agtcaaacaa ataaagaact
     1141 tcaagcagaa acacatatga gtagtgtaaa tcgtattcct gatttgcgcc tacctgctga
     1201 attttctgat cgagtgccaa atatagattt atcgacttat gaacaaaatg ggaaagtcac
     1261 ttctatttct gattggatgc aagcaaacgg attagacaga aaaagtcact ggtcggagat
     1321 ccttgaagta cttcactcag aactgatgaa taataggaag caatcaggag gggaaattac
     1381 ctttacttat gtttatatac cagacaatcg ttcattagaa ggtcatgatc ttattgttca
     1441 tccaaacgaa aaaataaaca aagaagagtt gatccaatca gcaacaaatt ccttaggtaa
     1501 acccgtaccg ttaaaggatg tatcggttac aatcaatgaa gtaccattgg aggatggtta
     1561 tttgaccaaa caaacaggtg attttacgat tatgtatagt tatcatgacc cgtattcact
     1621 ccaagaactc catgctcagt cactattaca tgttttacca ttaaacaaac agatagatca
     1681 aaaagaacaa aaaagacgag aagaaagctt gtcagaaaaa aaacaacaaa tggctcatgc
     1741 agtttctcca acagggaaag taaaacaaac aagaagccta gagttagcaa gaatatctag
     1801 aaaaatctca gaatctaata aaacgataag gcaagaagct catttggccc cacaagtttc
     1861 tggattggaa aatgaaattt tagagcctaa aataaaacaa caatcagaaa aagaatttgt
     1921 tgctaaacag tcggaagatc agaaggaatc agatgaccag aaggaaacga agaaaaaacg
     1981 cttgtcaact attgattcca ccgatgagca tctgcagccg caagtaccac ttcctagtcc
     2041 gggaacaccc gcacctggtg gaggtattcc ttcttctgct ttaggagatt tcatgcgagg
     2101 tatggcagga acatgggtat acgctaatcg aaatgaattt gacgcagatg actggttctg
     2161 atttatatct ctatctgtta tagtcaaata agtagctgag tcatatgtta tttggcataa
     2221 tggagacgag gagggataga aaaatgttag ataaaacgtt accttacgca gaaatctgga
     2281 tgacaagacc acttcaacaa aatgttccaa tcacgccttt agcggaaggt tttgaatttc
     2341 gattttatca aaaagaagat gaatctgctt gggcggagat tgagacttcc gttggggaat
     2401 ttcaaacgac agatgaagca cttgagtatt ttcaacaaaa ctttgctcct tatcctgaag
     2461 aacttgaaag aaggatgttt tttgtagaga caaaaaaagg agaaaaagta gcaacctgta
     2521 ccgcttggcg aaaaaaatca agagagcaag tgtatccggt ttttcattgg ttagcagtga
     2581 aaccagatta ccaaggaaaa gggctcgcaa aagcattgac tgccagagtc ttgcaagaat
     2641 ttcctaccct ccatacggac ggaccaatct atcttcacac acagacatgg agccatcagg
     2701 cgattgctct ttataaaaaa atgggtttta cttttattgc tgaaaatcta gacggcacac
     2761 ctaatccaga ttatgaaaaa gttatgcagg ttttaagtaa attagataaa taacgaaatg
     2821 gtgaaataag tcctcagtat tgggataaaa aacgaaatag tcattcctca tatcttactt
     2881 ttttgagtta atactatcgg ataactaatg gcatgccata cattcaaaaa agaaggggca
     2941 gtgacaaaag tattgtcact gccccttctc ttgtttttta gcatgtttta tcgtttgatt
     3001 tttttaggaa taaaattctt gatgaacgta aatttttggt aatcgtttcg actatagagg
     3061 taaccaaata cactgaaaac aactgctcca ataaaattaa caaataaatc cttcatagta
     3121 tccatgattc ccacgtctaa gtaaccattt tggatgattg ttttatctgt tttaccatct
     3181 gcattttgac tttcaatgat tgtccgagtg atatctggaa catgatagac agtgtttccg
     3241 tctttactta actccacact attgatttgc tggatgatcg tatctttttg catatcgaat
     3301 tgcagtaatt tatctgctga aaattccaca aactcccaca taacaccaac tgtcatcgaa
     3361 aaacagaagg aaacaactgc tagtaataaa ggagtcaagt tcatggtttt tgtattttta
     3421 ttgagcaaat aaacaaggga aaagccgaca cccccagcta aaaatccgct gaatgcatgt
     3481 agaaaagtat cccacattga aaaatagcca taaaaatcac ttaactctcc taaaactgtt
     3541 gaactaaaaa taaaagataa caaaatgatt tctagcatat ttggaatctg tatctttaat
     3601 atcttttcca gaaaataagg gatttcaaat aaaattaatg tcagtaataa aagcattgta
     3661 tttccccagt gttggttcca gacctgatcc actagcataa taacgacgat gatacgtaat
     3721 aaaatataga ttccgtttgt gattctacct gcagtttttg tactgttcgt aaaaaaggtt
     3781 ttcaaatgat tcataaaata actccttcat gtatatcctt aattatacta agaagcgtgt
     3841 gtttaccaaa gctatatgac ttaaagaaaa acagagttga tattgtgaaa aaaatcactt
     3901 aatatagtat aaggagaaaa gggggataca aatgaaaaaa ttagttgctg gtttattaac
     3961 agccgttgca cttcttgcta tgagcgcatg cggcgcagat cagaaaaata cagcgcagac
     4021 aagttctagt acgaaggaat ctgccgaagt atcatcaggc gcttctgaac aagtatatac
     4081 agatccaaaa gaaatgaaag aatcttatga tgtcgtgatt attggagctg gtggtgcagg
     4141 gatggcagca gctatcgaag caaaagatgc tgggttgaat ccagtaattt tggaaaagat
     4201 gcctgttgcc ggaggaaaca catctaaatc atcaagcggt atgaatgctt cagaaacaaa
     4261 atttcaaaaa gaagaaggaa tcaaagactc gaatgatgcc ttctatgaag aaacgctaaa
     4321 aggtggtgga ggaacgaatg ataaagaaat gcttcgatac tttgtcgatc actctgctga
     4381 tgcggtcgat tggctagatc aaaacggtat caaactggac aacttaacga tcactggagg
     4441 gatgagtgaa aagaggacac atcgtccgtc tgatggctcg gctattggtg gatacttagt
     4501 ggaggggtta ttgaataacg tccatgagcg ggaaatccct atttttgtca acgcagatgt
     4561 gacagacatt aagaaaaatg gggaaacggt caatgaagtg actgtacatg ttcaaggaga
     4621 agaaccaaaa gaggtcaccg gaaaagcaat cgtagttacc acaggcggtt ttggtgccag
     4681 caaagaattt attgaaaaat atcgtcccga tttagctgat tatattacga caaatcaaga
     4741 aggatcaact ggagatggta tcaccatgat tgaaaaatta ggtggacaaa ccgttgatat
     4801 ggataaaata caaattcatc caactgtgca gcaggatgag ggggtcttga ttggtgaggt
     4861 tgttcgcgga gaaggagcaa tcttggtcga tcaagagggg aaaagatttg tcaatgaaat
     4921 ggatacaagg gataaagtat ctgcagcaat tacagcattg cctgaaaaat cagcttattt
     4981 gatttttgac caaggcgtgc gtgatcgtgc cacagctatt gaattttatg accaaaaagg
     5041 atatgtcaca actggaaaga caatggaaga attagcagaa aaaatcgatt taccaaaaga
     5101 aacactagca aaaacagttg atggatggaa tacggatgtt gcggagaaaa aagatgctca
     5161 attcaaccgt gccacagcca tggaacatga cttatcgtct ccgaattatt atgcgatcaa
     5221 aatcgcacca ggaatccatt acacgatggg cggtgtgaaa atcaatacga acactgaagt
     5281 attagataaa gaaaaccagc caattagggg gttatatgct gctggtgaag tcacaggtgg
     5341 cttacatgga aacaaccgga tcggtggaaa ttcagttgcg gagatcatta tttttgggcg
     5401 acaagcgggc atacaagcag ctcgatttgc ttcggaaaat gaatgaaata gaacgtaaat
     5461 aaaaagaggt tgtgaaatca gcgttttgag ctaataccga gggtcagctg attgaacact
     5521 gtttagtgaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaagtaa
     5581 aaacagcttc ttatgttttt aacttggttg gacttattac cgcagatgca agcttttgaa
     5641 caccgtttat tcggaaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc
     5701 taaacacgta taaacggcgg aagcagaaga aattccttcg gaaataagct gaaattcaca
     5761 aaaatttgaa aagcaatttt cgtgaatttc ttcttatttc ttggagttaa acgcttctgt
     5821 cccagcctct tttttgatca gcatgatttt attcagttat cttcaaaatg atttttccga
     5881 tgtttttgtt tgcttccata tattcatgcg cttgtttgac tgcgctgaat tggaatgtac
     5941 ggtcaatgat tggccgaatc ttgccatttt ctagaaaagg cccagctttt tgcataaaag
     6001 tttgtgcgag ctctgcttta tactgatcac ttctaggtgt caataatgta ccaagcagtt
     6061 ggacacgttt cccaatcaat acaccaaggt ctatctcagg cacgatggtc ccacctagca
     6121 taccaatcaa gacccaacgt ccatcaacgg ctatagaagc taaattcttt tcccagtaag
     6181 aagcgccgat gaaatccaaa ataacatcga ctccccgacc ttcagtgatt tttcgtacct
     6241 cttcttgaaa gtcttgtttt ttatagttga tcaattcatc tgcaccaagt tctttacaaa
     6301 aggcgagttt ttcttctgat cctgcagtaa cgatgatttt cgcgtgagaa agctgtctag
     6361 ctaattggat cgctgctgtt cccacaccac ttgctcctgc atggatcaag acagtttcgc
     6421 cttcttgtaa ttttccaagc cagtaaagtg tttgataagc agtcaaaaaa acttctgaga
     6481 ttccagcagc agaaacatag tctagcgtat cagggagaag gattgcacga tcggcaggca
     6541 tcacagcata ttcggcataa ccacctagat tgactaatcc gtatactttt gtcccaggag
     6601 taaaagtgga gatatcactt ttattctcaa ctacctctcc agctacttcg actcccaaaa
     6661 tagggtaggg aggtttcaaa gagactgatt ctcttttcat aatatctgtt cgattgacag
     6721 ctgctgtatg gactttgatc agtaattcgc cttgttttgg tttaggaaca ggcacttcaa
     6781 tttgttctaa tacatctaca gaaccaggat gcttgattga aatggcacgc atggatctat
     6841 tcctcctttg cccattcttg gaatgctgta ttcaactctt tgctaccttc agaaagtact
     6901 agagtcgtac gagaaatatc cgtttcttcc actagagcgg caagtacagc agcaactgta
     6961 gagcgagtga tcgtttttga tgccttctca ttaggcttag ttaattgaat ggaagtaact
     7021 tcttcatcgt tagtcaatgt gactggttga agaatgacaa aatctaagtt agttcgtttc
     7081 agccattcat ctgcataatg tttagtaata taataatctg tcatggactc aggccatttt
     7141 gctggttcat ctgcataaac agcactgacc atcagatagc gagagacatg cgcattttca
     7201 gctgcgatca ctgttttgat tgcgccatcc aagtctactt gcagaagatt ctttccttga
     7261 gagccggcag caaaaatcaa tacatcgatg cctttgaatg cttcggtcat tttttccacg
     7321 gaccaagtta aatcaaaaga gacatacgaa acattctctt tttttactaa tgtttgggaa
     7381 gcaacatctc tcacccctgc aaaaatttca tgggaacttg gagctaaatc ttttatcagg
     7441 tgtcggccaa tttgtccgtt tgcacctaca acaaaaattt tcatttggat catcctttcg
     7501 acgtcaaatc tttccattca atagtaacac caaaagagaa aaaaatcaga gatcggctac
     7561 gatgactatc agttagtaag agaagggtgc ttgaagtatc ttaacaagac attgcatact
     7621 gctgcagtcg caagacctgc gacgattcct tcaggtatac cacttgtaaa aataaccgct
     7681 agaatagctg aataaacagc atttaaattt gttccgatga ctttggcata atcttgctgg
     7741 aataaaaagt agatcatatt catcactaaa atcgtattgg tcaatgaacc ggaaagtcca
     7801 gctaagaata aagaaacgga atctgctttt tgtttcatta gtttgcgcag acctttataa
     7861 acgaaataag gaaccacccc aatcaagatg cgaggaataa acgcgatcag caaggctttc
     7921 cagcttccat gttctgttcc gatgactggg ataaacggag aaaagacaaa agacaaaggt
     7981 gtttggataa ctgtgctacg gatcatgctg atcagtccaa atgtaccgcc aagaaaagca
     8041 cctagtcttg gtcctaaaac gatcgaagca atgattacag gaatatgcat ggttgttgca
     8101 ttgattggac cgatagggat aaaacctaaa ggcgtaacag ctaataaaat caaaatagct
     8161 aaaaacatcg cagttaatgt aaagtttttt gtatttttca taagtactcc ttttttctaa
     8221 gcatttcttt cattaagagt cagcatgacc tgttcgatga tcgtctgaat atcagctaag
     8281 gcaccttttc caaaatctcc acaagctaaa agagattctc ttggttcaat ttcctgatag
     8341 ccgacagatc tcaatgtttc cagattacgc tgagtgatcg ggttttgata catattcgtg
     8401 ttcatggcag gggcaatcaa ttttggtgtt cccactggaa gcgccattgc gactgttgaa
     8461 agaagatcgt ctgcaatgcc gtttgctagc ttgccgataa tgtttgctgt agcaggcgcg
     8521 atgagaaaca agtcagcttg ttttgctagt tcgatatgat tgattacctg cggatttgat
     8581 tcttgcatga cgtctgtatg gactgcgcgc ttcgacagag attgcaaggt taatggcgtg
     8641 ataaaatgtg tgctgctttt agacataatc acatctacct gggcacctaa tttgacgaat
     8701 tgacttgtaa gatcagcgct tttgtaagca gaaatacttc cagtaacgcc tagtaagatc
     8761 tttttcattt tgattcctcc agtctaattt tctcagtaat caatgcagca atctcagatt
     8821 tactttgagc ttcttccact gttccatctt tagataagag atagccgtgg tgtgtctcgc
     8881 catggatttc cgtcaaatca tttgcgaaaa taaaatcagt tttgttattt atcagactat
     8941 tttttgcgac tgccagaaga gattcctttg gtacatctac taatagtttg aaaccaatga
     9001 tttttgcttt tggctgccat tcacgtagat aagaaatgat ttttggtgtt ttcttcaaaa
     9061 cgagcacaag atgctcggtg ttagaagaga tctttgaaac agtggtatct gtctgttcat
     9121 tttccgcaaa ccaattgtcc agttcttctt gcgttgaaga agtgggtagg ttttttgcca
     9181 gctgttcttc tgaaaaacta aaagcaggag taaaatcact gactgccata ctgtggataa
     9241 tcgcatcgta gtgttctttt ttcgttagtt cttctaattg taaaaataag tccagtgcag
     9301 attcgatcgt ataaatcgtt atattggagt gtcttttcgg tttcagtgct tgtttcgtag
     9361 tcacgtaatc gattgtggta tccggattgg cagctaaata atcagctaat gcttgcccta
     9421 atcgtcctgt cgaatgattt gtaatagcac gtacttgatc gattttttca gtcgttcctc
     9481 cagctgtgat tagaatcttc atttatggtc acctacattt actagtgttc ttccttggtg
     9541 tgttccagca agtagtttag atgctgtttc aggcaattga tccagagtaa tctcttggac
     9601 gaccagttca tctgcaatct gcaaatccgc catctgttgc cataaagaaa gacgttgatc
     9661 tattggtaca ttgacagaat caattccaat caactggatg tttcgcagaa taaaaggcaa
     9721 gacagtcgcg tttagtttga ttcccccagc attgccacat aaagctactg caccgttata
     9781 agagatcaat ggaagaagac tgcttagctg ctcgccacct actgtgtcga tgacatagtc
     9841 gatttgctgt tttcctaaag cttttgttgt ctctggcaga aattcatcag gtcgtacgac
     9901 ttgcaaagca cctagacttt ttagccatgt gacagactct tcttttctgg aaaaggcaat
     9961 gattgactgg aatcctagtt tatgtaacag ggctatcgct gtactgccta caccgccaga
    10021 agcaccagta acgacaactt ttttatcgga ggtcatacct tgacggatta aagcgttcac
    10081 acacaacata gcagtaaacc ctgctgtacc aaggatcatc gcttgacgca gcgtcatatt
    10141 ttttggtaga ggaactaacc agtctcctgg tactttttga tattggctat aaccgcctgg
    10201 atgggtgacg ccaagcccaa aaccagtagc aagtacaaga tcttcttttg aaaaacgtgg
    10261 attgttactt tggacgacag ttccggataa atcaatccct ggagtcatcg gatatgttcg
    10321 tatcacctga ccagactcgc tcattgccaa tgcatcttta taattgacat cagaataggc
    10381 aatttttacc aagacttcat tttcagccaa ctcagtaaat ggcagatcac tgattgctgt
    10441 atggaaaaca ggttccttta ttacctgaaa agatcgaaaa gcgttcattc gtgagacact
    10501 ccttttaaaa ttttctttta tcataccata aagcctactc ttttattctt gttcttccgt
    10561 aaatttagac aaaaattagg tgaaaaataa agaatcaaac aactagaatt tattccaaaa
    10621 gataaagaaa tattcagcaa aaaaaatttt acaaagggtt gcctttttca ataaatttcg
    10681 tatactaata cgagtggtag taaacaggaa gtttactatt agaaaacttc gattcggagg
    10741 aaattatgga aattggtgag aagttaagaa atttgcgcat ccaaaagaat ttgacacaag
    10801 aagaactagg cgaacgcaca gatttgtcaa aagggtatat ttcccagttg gaacgagatt
    10861 taagttcacc atcaatggaa acattctttt ctattcttga agtcttaggt gtgactccag
    10921 aagaattttt tcatcaagaa gcagcgaatc tgcaagtggt ttattcaaaa gaagatcata
    10981 cggtttattt cgatgaagaa aacgggtatg aattggaatg gctcgtggct gattcgaatg
    11041 aaaaagaaat ggagcctgtc ttgctgactt ttgaaggtgc aggagaatat aagacgtttg
    11101 aaccttcatt atctgaaacg tttatttttg tattagaagg ggaattagag ttaagcttag
    11161 gagagacggt ctatgtggca aaagcaggac agtcgatcta ttatcaagcg acaaaacaac
    11221 atcaattaag gaatcatctc aaaaaacgaa caaaagtatt gattgttgca acgcaatcat
    11281 atttgtaata tagggggtaa aaacgtgggg aaaccaatca tttcatttga tcaagtagtg
    11341 aaacgctatg atgatgaaac agtattaaaa aaagtaagtt ttgagatcga acaaggaaaa
    11401 ttttatacac tgcttggtcc ttccggctgt ggtaaaacaa cgatcctacg tattatagct
    11461 ggattcaccg aagctacaga aggggacatc tattttgaag ggaaacggtt gaatgatttg
    11521 ccagctaata agcgacaagt aaatacagtc ttccaagatt atgcactttt tcctcatatg
    11581 aatgtttttg ataacgttgc ttttggattg aagatcaaga aaatgtccaa atcagatatc
    11641 gaaaagaagg taaaagatgc tttgcgtatg gtccagcttc ctggatacga aaaacgggag
    11701 attagtgaaa tgtctggtgg tcaaagacag cgtgtagcga ttgcacgagc aattgtaaat
    11761 gaaccgaaag tattgctatt agatgaaccg ttatcggcgc ttgatttgaa actacgtaca
    11821 gatatgcagt atgaactgcg ggatctgcaa caacgattag gaatcacgtt tatttttgtt
    11881 actcatgacc aagaagaagc gttggcaatg agtgatgaga tttttgtcat gaataaaggg
    11941 aaaatcgtcc aaagtggtac acccgtagat atttatgatg agccaatcaa tcatttcgtt
    12001 gctgattttg ttggggagag caatatcgtg gacggtgtaa tgatcgaaga taatctagtt
    12061 gagtttgttg gtaagcaatt tgaatgtgtc gatggcggga tgcgtctaaa tgaaccagtt
    12121 gaagttgttt tacgcccaga ggatttgacg atcacgacac cagataaagg aaaactagtc
    12181 gtaacggtcg atactcagct gtttcgtggt gtccattatg aaatcatctg ttatgatgaa
    12241 cagcaaaatg aatggatggt ccattcaacg aaaaaagcta aagaaggaag caaagtagga
    12301 ttggcctttg agccagaaga tatccatgtc atgcgtttca acgagtctga agaagaattc
    12361 gatgcacgtc ttgacagcta cgaagaatag gggggacaag aatgaaaaca atgcgcagga
    12421 tctattccgt cccttatatt ttgtggctcg gtttattcgt gatcgcgcct gtattaatga
    12481 tcatttatca atcttttttt gatatgaatg ggcaattcac gctgaataat tatctatctt
    12541 attttacgtc ggggacatcg ctttctatga cgatcaattc tgtatggtat gcatttttga
    12601 tcacgttttt cacgctgatc atcagttacc cgactgctta ttttttaaca aaactgaagc
    12661 acaagcaatt atggctgatg ctgattattt tgcctacatg ggtgaatctg ctgcttaaag
    12721 cttacgcatt tattgggatt ttcagtgtgc acggcagcgt gaatcatttc tttgatttta
    12781 tcgggatcgg gccgaaacag atattattca cagacttcag ttttctgttc gtggcaacgt
    12841 atatcgagat tccatttatg attatgccaa ttttcaatgc attggaagag atgaatcctt
    12901 ctttgatcag tgctagtaga gatttaggcg cgaatagctt tgagaccttc cgacgagtga
    12961 tttttccgtt atcattaaat ggtgtgaaaa gtggtgtcca agcagtattt attccttctc
    13021 tttctttatt catgctgact cgtctgattg gcggaaatcg ggtgatcact ttaggaacgg
    13081 ctatcgaaca gcatttcttg gttacacaaa actgggggat gggttctaca atcggtgtga
    13141 ttttaatcat tgctatgttc atcgtgatgc tcctgacagg cgagaagaaa aaaggaggtc
    13201 gctcataaat gaaaaaattt aaatggtcgt atctttattt agggatcgtc tttttattct
    13261 tatatgcacc gatcttctat ctgatttttt attccttcaa tgaaggagga acgatgaaca
    13321 gctttacagg atttacttgg gaaaattatg aagctgtttt tgaagataca cgtttgatca
    13381 ttatcgtatt gaatacgttc atgctggctt tcttatctgc attgatcgcc acgatcatcg
    13441 ggacatttgg ggctatggga atctattaca cgaaaaaacg acgtgcacgg acagcgttgt
    13501 tgagcatgaa taacatctta ttagtctctc ctgatgttat tatcggtgct agtttcttga
    13561 ttttctttac actactagga ttcggattag gttttcagag tgtattgctt tcccatattg
    13621 ctttcagcat tccaatcgtc gtcttgatgg tcttgccaaa attgcaggaa atgaacgatt
    13681 caatggtcga tgcggctaga gaccttggtg ctaataattt ccaagtagtc aaaaatatca
    13741 ttttgcctta tctttctcca ggaatcatag ctggatattt tatggcattt acctattctc
    13801 ttgatgattt tgcggttaca tttttcgtca caggaaatgg ctttacgacg ctctcagtag
    13861 agatctattc tcgtgcaaga caaggaatca gtttagaaat caatgcgcta agtgcgttag
    13921 ttttcttgtt ctccatgata ttggtcattg gatactactt tattagtaaa gaaaaccgtc
    13981 caaaacggct gaagaaaaac agaagagtac gcgagggggt ggcacggctg cgatgaaaaa
    14041 attacaatct ctgtttttag gtattctcat cattattgcg gtgctgctgc ttggtgttcg
    14101 tcaacttgaa aaaacaagtg gcatgagtgg agcaaaggta cttaccatct ataactgggg
    14161 agattatatc gatcctagtt tgatcacgaa atttgaaaaa gaatatggat acaaagtgaa
    14221 ttatgaaaca tttgattcta atgaagcgat gttcacaaaa atccagcaag gtgggacaaa
    14281 ctacgacatc gctataccaa gtgaatatat gatccaaaaa atgatcaaag aaaaactagt
    14341 acttccatta gatcattcga agatcaaagg attaaataat attgatccac gatttttaga
    14401 cttggatttt gatccagata atcagtattc gattccatat ttttggggaa ctttagggat
    14461 cgtatataac gataaattct ttgatgcaaa tcaaattaag cattgggatg atttgtggaa
    14521 gccggaatta aaagacagtt tgatgctgat tgacggtgca cgagaagtta tggggctttc
    14581 tttgaatagt ttaggctatt ctttgaatag taagaatatg gcacagttga cagaagcagc
    14641 aaataaattg aatcatttaa caccaaatgt caaagcaatc gtggcagatg agatcaaaat
    14701 gtatatgatc aatgaagaag cctccgtggc agtgacattt tctggcgaag ctgccgatat
    14761 gatgtgggaa aatgaacatt tacattatgt gatcccacca gaaggatcca atctttggtt
    14821 tgataatatc gttatgccaa aaaccgtgaa aaataaagaa ggtgcctatg atttcatcaa
    14881 ctttatgcta gaaccggaaa atgcggcaca aaatgcagag tatattggtt attctacacc
    14941 aaatgaagaa gcaaaagcgt tattgccaaa agacatttcg tcggacgaac aattctatcc
    15001 atctgatgac acgatctccc atcttgaagt ctacaaagat ctaggatcga aatacctagg
    15061 catctataat gacctattct tagaattcaa gatgtatagg agataatggc aaaactcagt
    15121 aagaatgggg acttatcaac gttctaaaga gctaaaaatc gtcctttttc tatctgagtt
    15181 ttccaatctt ctaccaaaag cggatgaaac gccgcttttt ttgtgttatt ttattttttc
    15241 taccacgttt ttctaccaga gaaaagtgga caaaaccatt gtaaaatagg gcccgagacg
    15301 ggctagtaaa tctaagattg aaaaagttac agaaggataa agtaattgga aactatgcaa
    15361 atatacttaa cccttctgta atctattaat aaaactaata tatgaatcca gttcaatatt
    15421 tgtagctatg aaaaaacata aaaatcatat tagataaaaa ctaaattggt agataaatta
    15481 ttttgtcaga tatctgaggc aaatattcga ctatttgtgt ttcaaagtaa aaattggaat
    15541 acaaatatag aatagacata ttgcagccga tagtttatta tgcttttaga cacattaaac
    15601 tggaggaaaa aatgaaaaag agcgctaaag atcgagtttt tgatgagctg atacgactaa
    15661 cagggaatat gtcttctgtc actgccgaga aaatttcgaa gaatctaggt atctctcgtc
    15721 agaatgccag ccattatttg acgagattag tggaagataa aaaggtcgag aaattaccgg
    15781 gaaagcctgt tttgtggaag cctttagatg aatatgcggt tgtagataat acggagcaaa
    15841 taaacgaagc ctttcattct gtagttggtc atgacggaag tctgagagag gtcattcaaa
    15901 aatgtatagc cgctgtcaaa tatccgccta acggactcag tgtattaata aatggagcca
    15961 cgggtgttgg aaaaagtttt ttagccacaa aaatttttga atacgctatc catgagcaaa
    16021 ttattgaaaa agatgcacca tttgctatct taaactgtgc cgattatgcg gacaatcccg
    16081 aactgctttc ggcaacactg tttggataca agaagggggc ctttacgggg gctgaaaagg
    16141 ataccgatgg tttattggca acggccaaca acggctatct ttttctcgat gaggtccatc
    16201 gcctatcgaa agaaaatcaa gaaaagctct ttctatttat tgatactgga aactatcgtc
    16261 cagtcggtga aaatgtaaat tggcattctg ctaaggttcg ttttattttc gccacgacgg
    16321 aaaaaggtga aaattattta ttagacacct ttgatcggcg tattcaaatt agtgttatgt
    16381 tgccaacttt tgaagatcgc cccattcgag aacgattaga gctgattcaa ttattttttc
    16441 aaaatgaagc ggatgtttta caaaaagata ttattgtttc aagagaagcc ttgtctttaa
    16501 tgttatctca tccctttagt gggaatattg gtaagctgaa gaatatcatt aaaatcagtt
    16561 gtgcggatgt gtatagtcga acacaagaag aaccattaac gattgggaaa aatgagatct
    16621 tgattcagtt aaatatgctg gaatccgaag tagaaagctt gccgattgct agtttattga
    16681 taaagaaaaa tcaaaagata aaaacggatc gaatcaaacc gtttgattat gattcgattt
    16741 tggaaaaaat tactcagctg ataaatgaag gtaatttcaa tgaaaatttt tcttcgataa
    16801 agaatgaagt acagcatttg gtgcatcaca ttgataagga ttctttttta tcaatgagta
    16861 gaaaattgat gattcagatg tttagaaagg tctgggtatc cgttttagga aaaacgtacg
    16921 gattgacgac gagtggacct gttgcagaaa ttattagcag atcctatgtc atttccccaa
    16981 gctataagac agacttaacc gggataaatc gtacattagc tgcaaatcta cctcggacga
    17041 cttacttatg taatcagttc ttggagcatt taccaccgct ctcagaaaag gacgagaact
    17101 ttctaagact gcttattgtc gtgactttat ctgattatgt agatgaatcc atcgagctga
    17161 agggcctgtt gcttgctcac ggagatagta cggctagcag cattcaagca gtagtgaatc
    17221 aattatgcgg caattatgtt tttgaagcgt tggatatgcc agtagagagt aatgtgtcag
    17281 agattgtcga atcgacaagg aatttcgtga aacggcaagt gaatacagat agtctagtgc
    17341 tgatcgtaga tatgggctct ttaaatcaaa tttacacaca gatcaagaac gatttaaaag
    17401 gggagttact tcttctgaat aatttgacga cttccattgc acttgatatt ggcttgaaga
    17461 tgacgatgaa tgcgccattt aaacagattg cggaggatgc agcagacaag tattcaatca
    17521 atgttcaata ctttgaaggc ttttctcaaa gtagcaacat tatcatttcc tgtatgtcgg
    17581 gtttggggat ttcggacaaa ttgaaagatg tttttcgtca tcatttatcg gatgaatcca
    17641 tcgaagtttt cacgaaggac tacagagaac tacgtgaatt aatcgaccaa aatgatgaaa
    17701 cttattttga caagacaaaa ttggtcatca cgacttcgga tcttccacgt tccttttcaa
    17761 ttcctaatat taatgtttat gacatcttag acggtgatgg agcagccaat ttggagcata
    17821 ttttgagtcc tgaaatgaag ccggcagaat ttaaccgctt gattcaggag ctagtaaaat
    17881 tcttttcgtt ggaaggaatt gcggaccgtt tgaactttct gaacccaacg atcgtgatga
    17941 gtgaagtgga aacagtcatt tctaaatatg aaaattacta tcatttcact ttaaatggcc
    18001 gtgtaaaact aaatctctat atgcatacgg cattgatgat ggaacgttta ttcttggctc
    18061 ggacagaaaa atctgaagaa ccgaattatg atttgaaacc agatgaagat gaattttatt
    18121 atgtttctag aagtattttt caatcaatgg agatgaaata taattttaaa gtcaatgctt
    18181 atgagctttc gctgctctat gaattattag gaccgtatat tcaaaaataa agtgtctaaa
    18241 aaagtgtcta atctgttttt tttaggttag acactttttt taatgtgaat taacgtgatt
    18301 aaaccaatgt ttttaaaagt tggcacagga attgcttata taaaagtgaa cagaaagaaa
    18361 ggaattaacc atatgaagaa aattctaata gcgactcacg gtcacttagc ttcaggcttt
    18421 cttagcagta ttcaattact gacggggaag gttcaagaga ttacggtgat taatgcttat
    18481 gtggatgagt gtgattttga acaggagttg aatgtatttg taaaccaggt gaacgagcag
    18541 gatcagattt ttgtttttac cgatttattt ggcggaagtg tcaatcagaa gattaccaaa
    18601 acctttttgg agaaagagat tgctgtaact attttgtctg gctttaatct gccaattctg
    18661 ctcgaaatag tattggcaac caaggaatta acaaaggagg atattcagga actggtaaat
    18721 aaatgccaac aggaattaaa gatgaccatt cttgatgagg tacatgtagt aaatgaagag
    18781 gaagattttt tttaggagga agaaaaatga ttaaagcagt gcgaattgat gaacgattaa
    18841 ttcatggaca agtagcgatg acttggacaa agagtctaaa tttaaccggg ttagtagtag
    18901 caagcgatga ggcggctacc aacgatattc aaaagatgac attgaagatg gctgcaccat
    18961 cgaatgtcaa agtcattatt aaaacagttg atgacgcgat tcatttgtta aaagatccgc
    19021 gggcgaagga catgcgcttg atggttttag tccctaatgt caaagatgcg gtaaaagttg
    19081 cgaaagcttt cccaacggaa atcgaattaa tgaacgtggg gaatgctggg aaaatgacac
    19141 cgccatcgga agataagaaa accttatcaa aggaagtgat gttaacgacg tcagaaattc
    19201 aagacttaaa agaattagtt gaactttatc cagataccgt ttttcagcct acaccggcga
    19261 tggaaaaacg ttcagctatc tctattttga gtgattttta gaaaaaggaa ggagaaaaat
    19321 tatgtatgat gcatttgtag tcgctttggc cgtttttatt ggaattgctg gacatgaaat
    19381 gttcgggatg tccatgctga gtcgtccgat tgttgttgct ccgttagcag gagcgttgat
    19441 gggggatttg cagacggggt tgattgtcgg ggcgtcacta gaagccatct ttatgggtgt
    19501 cgtcaatatc ggaatctcta gtacggcgga gccttctttg gctgctgggc tggctacagc
    19561 gttcgcaatc aaaatgggag gaaacgtgga tgcgattatt cccattgtct ttccactagc
    19621 agtattagga ttacagttaa tgaatatgat tttttctttt gtatgtggac cgatggctgc
    19681 taaatttttc aaatttgcaa aatctggtga tcaaaaagga atcatcaatc tgcacttctt
    19741 tatgtggttt gtccactatg cgctttatgc tcttattcca ttctttgccg ttttatttgg
    19801 agcagatgtt gtcaaaagcg tcttggataa tattccagag gtcatcatga acggattaac
    19861 agtcgctgga aatctgctgc cggcagttgg gatggcgatg ctgttacgga tgctttggag
    19921 taaaaatatt gctgtgtggt ttttctttgg ggccgttgtt atggcgtatc tcgagttacc
    19981 attgattgca attgccgcag ttggaacgat tattgcaatt gttatagccc aaagagatct
    20041 acaactaaaa aatatatctg ttcatgcagt tcaaagcgat gctgctgtaa atgcaacgct
    20101 tgaccaagaa gaggaggatt tctttcaatg aaattagctg atggaatttc taaagatgag
    20161 aaaaaattgg ttcggaagat gttttggcgc tcgatgacta tgtatgcttc ggtgaatccg
    20221 gtgacgatgg gcggcggtgg tttcgcctat tctatgatgc ccttcattaa tcatttctac
    20281 aaaagtgaag aagatcgagc tgcggcgctg gaacgtcata cacagtattt ttcgacgacc
    20341 attccttgcg cgtcctttgt catggggatt gcggcatcga tggagaagga aaattctgaa
    20401 aaagctggtt ttgacgtgga aagtatcaac gcgatcaaaa cgagtttgat gggaccattg
    20461 gctggaattg gcgattcatt gttctgggga gtttggcgtg tcgttaccgc gggactagcg
    20521 atcaacttag ccaatgccgg aaatattttg gcaccaatta tctttttagt tatgttcaat
    20581 atacctaatt acttgatgcg atactatggc ggcgttttag gctattcatt aggctctaaa
    20641 tatattgaaa agctgtatgc gaacgggtta attgaaattc tgacaaaagc tgctagtatc
    20701 ttgggtctga tcatggtagg tgcaatgacg atcagtatgg tcaaattcaa taccgttttg
    20761 agcttttcaa tgaagggcga agaactaatg aatgtccaag aaatcctcga tagtattttt
    20821 aaaggaattg taccgttatt ggtaacattg agctgtttca aattactaga taaaaaagtc
    20881 ggcgtcatca aaattatttt tggaatggtc gtcttgggaa ttttattgtc attacttgga
    20941 atcgcatagt aggaagctgc agctactagg ctgcagtttt tttagcaagg agggaaaaga
    21001 tgactattaa tgaagtaatt tattcaccca aacacccatt ttttaatgct gagttaaacg
    21061 acggaaatgt gactacttca aacgaataca gctactatcg gaatattcct gatgtaaagg
    21121 gattgacctt cgatgtaagt aatcaaaaga cattagcaaa ccttgatgtt tgcgggacga
    21181 ttcaaacgtt gaccttttat cgagaaaatt tactaactga ggaaaaacca ggtgtttggg
    21241 tcaataaaca gctctctcaa accaattcgt tatccttaaa ggttgaagta aacgggattg
    21301 tctaccattt gtcagaatcg gatcatcgta ttgaagtcga tgtgattcaa gactgtttgc
    21361 ctagatatat tcatcattat tcgacgttta aggtcattgt agtatccttt gctcccatac
    21421 tggctaataa gcgtttaagt atgcttgttc aacaggttta cattgtgaat gaaacacacg
    21481 aaagccttca agtttcagtg aaagatgtgc cttcgtatca agagaagtat tcggatcagc
    21541 aaaatgtgtt gatttctcaa aaaggaaata aggacacgat cgcacaacag gaagtggcaa
    21601 gcttcgccat tgcttttgtg gacccaaatg cttttgaaga agtaatgact tttcaggaat
    21661 ctgatatcga aaaatggctg aaggaaacat tgaactattt tgctcagcta tttgggcagc
    21721 tgtcaatgcc aaacgataga gttgtccatc tctatcgtcg tgcactttat caaagctttt
    21781 ctagtttcgg tatgaatcga cagggacagg tcgtcggcag caattggggc agctatcctg
    21841 ctactaatcg aatttggaat aaggatatgt attacgcatc attgccattc accatgtttg
    21901 aaccggagtt atgtcaaaaa acggttctat ggtttgatca atatggcgtt aagtttcctg
    21961 gttcaaaatt tacaggaggt atcaatcatt ctctgagtaa ttcgttatcc agtgcgttac
    22021 tggctagtct ttattttgaa catactgggg atacaaaatt ctttgagcgg tgtccgcagg
    22081 ttctactgaa tgcttcaaga attattgagg acatattagc tcaacgtcgg tcaggggaac
    22141 caatgctttt tccatctgtt tggttatcag acgcctttgc acttggaaag tatcataccg
    22201 gcagcaatct ttgtctttgg aaggcctgta ttggacttgc agaaattttt gaagccctag
    22261 aacaactgag tcttagcaag cgatacaaaa acattgcctg taaactaaag gaatcaattt
    22321 gtaaacaaat gactatcgat ggtccttttg gtgagcaatt tttggaggga atcggtgatg
    22381 aggagaaaac aacctattca gtgaagcact atcaaaaacc gattcttgag caagggttaa
    22441 tctttttaag tgatgtgatt gtggatggaa aaattaattt attgatgcat gatggagaag
    22501 aatcagacac tacgttgatg cctttttatc aatttttaga taataaagat catttatatc
    22561 agaacaccat ggccttttct gctagttctt tcaatccaac ctatagcgag gaaatcaaag
    22621 gcatcacttg gggattagaa tccggcgcca cttttcctgg ctttatcact gttttaatga
    22681 gcgagctgca caaccctcaa gctttcgtaa cccgattaga agaactaatt tgtttggcag
    22741 atttagacgg ttcgtggtgg tggtggccgt atcgcttaga ggctcaacaa ggagaagtcg
    22801 tgcgagactt tggctgcggc aaatgcggct gggcatcggg tctttttgtc agcctaatga
    22861 tcagtcaata tttcggattg aaattcaaaa aaggagtatt gcaaattgat cctgttgata
    22921 atttaacgtt ttcttggaag aatttgaagt tcggtcaagc cttcatttcg attgaatgta
    22981 cgcaatccga gttgagtatt tcaaatttgt cagaaaagcc attgaaaata agtgatacga
    23041 aaaaaattct tcacgtagaa aagggaaaaa cgattcacat tcaaaggaga aaaagatgag
    23101 tatactaaaa aatattaccc aatttaaaaa aatccagagt cgagcaatca ctcccgaaaa
    23161 tccaacaggc gagaaaggta aagctgcgat gttgccaagc gagctaggac caagccgcaa
    23221 aggtcgtggc gcaattccgc tgacttctgg tgaagaaact gtgattgcgg atattactgg
    23281 aacgggaata attcgtcata tgtggatgac gattcgtgat cgaacagaat ttggcagttt
    23341 tgttttacgt gatttaatct taagaattta ttgggatggg tcggatagcc ctgctgttga
    23401 aagtccttta ggggatttct tttgtaatgg gtttggagag cgttgcgagg tgaactcgtt
    23461 gccgatagtg gttaatccta cagggggctt taattcctat ttcgaaatgc ctttccaaac
    23521 atccgctaaa attacgatcg agaatttaca tccgaaggat atgtcctcat ttttttatac
    23581 gataaattac gctttggtgg acgaattgga agaaaatagc ctatattttc acgcaaattg
    23641 gcatcgggaa cgcattacca aattacagga ggattataag ttaattgatc gattaaaggg
    23701 tcaaggctat tacgtgggta cttaccttgc gcttacctgc ctagaacgtt attggtgggg
    23761 cgaaggcgag tttaaattct acattgatgg ggatagtgag tatccgaccg taacctcaac
    23821 aggttcagaa gattattttg gcggggcgtg ggcctttcat gagtacgatg agttcggacg
    23881 tccacatgcg aaaaactatt caacagcctt tttagggtat ccttaccaat caaatagaga
    23941 tgccacaaga gatcgttttg aaacgggaaa attgaatgcc gttcatgcct ttggtgacga
    24001 cgcaatgcca cgacatggtc tttatcgttg gcatcttcaa gaccccatct gttttaccga
    24061 agatttatcg gtcactttac aacaaatcgg caacgatgat gttcgcttat ttgagcggca
    24121 agacgatgtt gctagtgtcg cttactggta ttcaacagaa gcttcaggaa atactaaacg
    24181 tcatttcact gatcgagaac gcttgccgcg ttaatgaagt gtttttcaca tattcgaagg
    24241 gaggaaccta tgatgatata tggggcaatt gaagctggag ggactaaatt tgtctgtgca
    24301 gtcggtactg aggaattaac gattttggaa agagtcagtt ttcccacaac aactccagtt
    24361 gaaacaatga agcaggtcat tgattttttt aaacctttta aggaacaatt ggcaggcatc
    24421 ggggtcggct gctttggtcc aattgatatt caatgcaaat caacgagttt cggtcatatc
    24481 acatcaacac caaaacttgc ttggcaaaat ttcaattttg taggaacgct aaagcaatat
    24541 ttcaatattc cgattgaatg gacaacagat gtcaatgcgg cttgctatgg tgaatatgtt
    24601 gctggttctg gcaaagggtt agcaggtgtt gcatacttca ctgtgggaac aggtatcgga
    24661 ggtggtgcct tgttcaatgg gactttcgtg gaagggttca gtcatccgga aatggggcat
    24721 atgttgatca agcgacatcc aaaggacaat ttttcaggaa actgtccctt ccaccaagat
    24781 tgtttagagg ggatggcagc aggaccagcg attgaaaaac ggttgggtgt aaaaggccag
    24841 aatttattgg ctgacgattc gttttggcag attgaagcct tttaccttgc ccaatgtgca
    24901 tacaatacaa cactgatgtt ttcgccagat agaattattt ttggcggtgg tgtaatgaaa
    24961 caagaacaca tgaagaaaaa agttcaggat aaatttgttg agcttataaa tggatatgtt
    25021 gaaataccac caattgatag ctacattatt acgcccgaat taggtgataa tgccggaata
    25081 atcggcggat tagcattggc cagaaaagcg gtaagaaata agcaaccata attaatgaat
    25141 gtttcattga tactcatgtc aaaagtattt aaccgagtaa tcaaatgatc aaatgaagtt
    25201 ggataaagcg aaaatgaatt caaataaaaa ggctctaagt caaatcgtgt tgttttcatt
    25261 aaatcactga aaggaaatgc ttctgcgttt ccttttttct ttttgttgtg cgctgtatac
    25321 cttgaggata ttcactggtg gcgtacactt aaatagtaat atattgtgtt actttatgtc
    25381 tgtggtaata gttatagttg cttaccaatg tatgttcatt tttcgaaatg ttgacttcat
    25441 aatccttggc ttaatgtttg aatttttttg gtgatagatt ttttcagccg tataaaataa
    25501 atcgtaattc tattatagag agttgtgatt ataaaaag
//
LOCUS       DACGDM010000029        25217 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.029, whole genome shotgun sequence.
ACCESSION   DACGDM010000029 DACGDM010000000
VERSION     DACGDM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.029"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            12..84
                     /locus_tag="IXR05_001329"
     tRNA            12..84
                     /locus_tag="IXR05_001329"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="IXR05_001330"
     tRNA            88..160
                     /locus_tag="IXR05_001330"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="IXR05_001331"
     tRNA            168..249
                     /locus_tag="IXR05_001331"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="IXR05_001332"
     tRNA            267..339
                     /locus_tag="IXR05_001332"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="IXR05_001333"
     tRNA            351..422
                     /locus_tag="IXR05_001333"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="IXR05_001334"
     tRNA            439..524
                     /locus_tag="IXR05_001334"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="IXR05_001335"
     tRNA            535..608
                     /locus_tag="IXR05_001335"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="IXR05_001336"
     tRNA            618..691
                     /locus_tag="IXR05_001336"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="IXR05_001337"
     tRNA            711..783
                     /locus_tag="IXR05_001337"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="IXR05_001338"
     tRNA            811..884
                     /locus_tag="IXR05_001338"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="IXR05_001339"
     tRNA            898..971
                     /locus_tag="IXR05_001339"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="IXR05_001340"
     tRNA            995..1084
                     /locus_tag="IXR05_001340"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="IXR05_001341"
     tRNA            1097..1170
                     /locus_tag="IXR05_001341"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="IXR05_001342"
     tRNA            1189..1264
                     /locus_tag="IXR05_001342"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="IXR05_001343"
     tRNA            1266..1336
                     /locus_tag="IXR05_001343"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="IXR05_001344"
     tRNA            1350..1423
                     /locus_tag="IXR05_001344"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="IXR05_001345"
     tRNA            1448..1535
                     /locus_tag="IXR05_001345"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="IXR05_001346"
     tRNA            1557..1628
                     /locus_tag="IXR05_001346"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="IXR05_001347"
     tRNA            1651..1740
                     /locus_tag="IXR05_001347"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="IXR05_001348"
     tRNA            1753..1826
                     /locus_tag="IXR05_001348"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="IXR05_001349"
     tRNA            1845..1917
                     /locus_tag="IXR05_001349"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="IXR05_001350"
     tRNA            1921..1993
                     /locus_tag="IXR05_001350"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="IXR05_001351"
     tRNA            1998..2068
                     /locus_tag="IXR05_001351"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="IXR05_001352"
     tRNA            2081..2154
                     /locus_tag="IXR05_001352"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="IXR05_001353"
     tRNA            2166..2237
                     /locus_tag="IXR05_001353"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     gene            2503..3696
                     /locus_tag="IXR05_001354"
     CDS             2503..3696
                     /locus_tag="IXR05_001354"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAQ4259866.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="IXR05_001355"
     CDS             3826..5298
                     /locus_tag="IXR05_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4259867.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="IXR05_001356"
     CDS             5381..6169
                     /locus_tag="IXR05_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAQ4259868.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="IXR05_001357"
     CDS             complement(6236..6904)
                     /locus_tag="IXR05_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4259869.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="IXR05_001358"
     CDS             7019..8731
                     /locus_tag="IXR05_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259870.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10503
                     /locus_tag="IXR05_001359"
     CDS             8734..10503
                     /locus_tag="IXR05_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259871.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10708..11274)
                     /locus_tag="IXR05_001360"
     CDS             complement(10708..11274)
                     /locus_tag="IXR05_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4259872.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(11274..12230)
                     /locus_tag="IXR05_001361"
     CDS             complement(11274..12230)
                     /locus_tag="IXR05_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAQ4259873.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(12230..12886)
                     /locus_tag="IXR05_001362"
     CDS             complement(12230..12886)
                     /locus_tag="IXR05_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4259874.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            13256..15274
                     /locus_tag="IXR05_001363"
     CDS             13256..15274
                     /locus_tag="IXR05_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4259875.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            15701..18115
                     /locus_tag="IXR05_001364"
     CDS             15701..18115
                     /locus_tag="IXR05_001364"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAQ4259876.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            18463..20016
                     /locus_tag="IXR05_001365"
     CDS             18463..20016
                     /locus_tag="IXR05_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4259877.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(20397..22181)
                     /locus_tag="IXR05_001366"
     CDS             complement(20397..22181)
                     /locus_tag="IXR05_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259878.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(22196..23917)
                     /locus_tag="IXR05_001367"
     CDS             complement(22196..23917)
                     /locus_tag="IXR05_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259879.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            24017..24778
                     /locus_tag="IXR05_001368"
     CDS             24017..24778
                     /locus_tag="IXR05_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4259880.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         7802 a         4634 c         5365 g         7416 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
    10561 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
    10621 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
    10681 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
    10741 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
    10801 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
    10861 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
    10921 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
    10981 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
    11041 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
    11101 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
    11161 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
    11221 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
    11281 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
    11341 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
    11401 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
    11461 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
    11521 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
    11581 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
    11641 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
    11701 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
    11761 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
    11821 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
    11881 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
    11941 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
    12001 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
    12061 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
    12121 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
    12181 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
    12241 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
    12301 acagccaaga aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca
    12361 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
    12421 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
    12481 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
    12541 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
    12601 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
    12661 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
    12721 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
    12781 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
    12841 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
    12901 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
    12961 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
    13021 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
    13081 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
    13141 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
    13201 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
    13261 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
    13321 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
    13381 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
    13441 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
    13501 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
    13561 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
    13621 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
    13681 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
    13741 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
    13801 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
    13861 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
    13921 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
    13981 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
    14041 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
    14101 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
    14161 ggaaaatggc tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg
    14221 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
    14281 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
    14341 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
    14401 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
    14461 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
    14521 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
    14581 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
    14641 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
    14701 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
    14761 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
    14821 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
    14881 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
    14941 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
    15001 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
    15061 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
    15121 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
    15181 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
    15241 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
    15301 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
    15361 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
    15421 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
    15481 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
    15541 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
    15601 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
    15661 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
    15721 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
    15781 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
    15841 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
    15901 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
    15961 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
    16021 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
    16081 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
    16141 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
    16201 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
    16261 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
    16321 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
    16381 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
    16441 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
    16501 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
    16561 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
    16621 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
    16681 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
    16741 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
    16801 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
    16861 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
    16921 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
    16981 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
    17041 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
    17101 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
    17161 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
    17221 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
    17281 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
    17341 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
    17401 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
    17461 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
    17521 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
    17581 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
    17641 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
    17701 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
    17761 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
    17821 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
    17881 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
    17941 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
    18001 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
    18061 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
    18121 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
    18181 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
    18241 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
    18301 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
    18361 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
    18421 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
    18481 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
    18541 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
    18601 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
    18661 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
    18721 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
    18781 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
    18841 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
    18901 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
    18961 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
    19021 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
    19081 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
    19141 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
    19201 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
    19261 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
    19321 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
    19381 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
    19441 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
    19501 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
    19561 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
    19621 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
    19681 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
    19741 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
    19801 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
    19861 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
    19921 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
    19981 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    20041 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    20101 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    20161 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    20221 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    20281 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    20341 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    20401 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    20461 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    20521 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    20581 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    20641 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    20701 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    20761 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    20821 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    20881 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    20941 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    21001 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    21061 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    21121 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    21181 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    21241 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    21301 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    21361 aaggcgagtt gattaatgaa acgaatggcc ggatagatag cacagttcat aaattgagca
    21421 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    21481 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    21541 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    21601 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    21661 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    21721 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    21781 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    21841 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    21901 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    21961 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    22021 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    22081 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    22141 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    22201 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    22261 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    22321 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    22381 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    22441 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    22501 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    22561 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    22621 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    22681 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    22741 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    22801 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    22861 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    22921 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    22981 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    23041 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    23101 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    23161 aagcataaac gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt
    23221 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    23281 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    23341 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    23401 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    23461 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    23521 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    23581 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    23641 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    23701 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    23761 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    23821 gtacacctaa tgtaccggcg atttctaaac agatcatcac aaaggtaagg agagcgagtc
    23881 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    23941 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    24001 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    24061 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    24121 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    24181 tttttataga aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt
    24241 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    24301 gatgaaacaa aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga
    24361 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    24421 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    24481 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    24541 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    24601 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    24661 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    24721 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    24781 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    24841 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    24901 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    24961 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    25021 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    25081 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    25141 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    25201 aatcaaatag tccctac
//
LOCUS       DACGDM010000030        25090 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.030, whole genome shotgun sequence.
ACCESSION   DACGDM010000030 DACGDM010000000
VERSION     DACGDM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.030"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="IXR05_001369"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="IXR05_001369"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAQ4259881.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="IXR05_001370"
     CDS             complement(1172..1867)
                     /locus_tag="IXR05_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAQ4259882.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="IXR05_001371"
     CDS             complement(1880..2596)
                     /locus_tag="IXR05_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAQ4259883.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="IXR05_001372"
     CDS             2926..3534
                     /locus_tag="IXR05_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAQ4259884.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="IXR05_001373"
     CDS             3859..4182
                     /locus_tag="IXR05_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAQ4259885.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="IXR05_001374"
     CDS             4364..5734
                     /locus_tag="IXR05_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAQ4259886.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="IXR05_001375"
     CDS             complement(5864..7165)
                     /locus_tag="IXR05_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4259887.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9510)
                     /locus_tag="IXR05_001376"
     CDS             complement(7519..9510)
                     /locus_tag="IXR05_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAQ4259888.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="IXR05_001377"
     CDS             complement(9654..9920)
                     /locus_tag="IXR05_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4259889.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="IXR05_001378"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="IXR05_001378"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAQ4259890.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="IXR05_001379"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="IXR05_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAQ4259891.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="IXR05_001380"
     CDS             13264..13827
                     /locus_tag="IXR05_001380"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4259892.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="IXR05_001381"
     CDS             complement(14080..14601)
                     /locus_tag="IXR05_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAQ4259893.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="IXR05_001382"
     CDS             complement(14604..15446)
                     /locus_tag="IXR05_001382"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAQ4259894.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="IXR05_001383"
     CDS             complement(15439..16164)
                     /locus_tag="IXR05_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAQ4259895.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="IXR05_001384"
     CDS             16340..16636
                     /locus_tag="IXR05_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259896.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="IXR05_001385"
     CDS             17204..18796
                     /locus_tag="IXR05_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4259897.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="IXR05_001386"
     CDS             18809..19549
                     /locus_tag="IXR05_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4259898.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19717..21066
                     /locus_tag="IXR05_001387"
     CDS             19717..21066
                     /locus_tag="IXR05_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4259899.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21194..21784)
                     /locus_tag="IXR05_001388"
     CDS             complement(21194..21784)
                     /locus_tag="IXR05_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4259900.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            22020..23099
                     /locus_tag="IXR05_001389"
     CDS             22020..23099
                     /locus_tag="IXR05_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4259901.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
     gene            23320..24672
                     /gene="brnQ"
                     /locus_tag="IXR05_001390"
     CDS             23320..24672
                     /gene="brnQ"
                     /locus_tag="IXR05_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4259902.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         7177 a         5134 c         4886 g         7893 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagtcattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaaataaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaaaattttg gaatcttagt tgtgtttttc agaaaactct cttaatatgg
    19681 aagtaattaa acttttttag ttaggatgat ttaaaaatga atgaagagca agaactgcag
    19741 cgtggactga aaaatagaca tgtccaactg atttctattg gcggagcgat tggaacgggg
    19801 ttgtttttag gttccggaaa gtctatccag ctagctggcc cttcgatatt gctcgcctat
    19861 cttattactg gatgcatctg ttttttcatt atgcgtgcgt taggcgaact tctgttatca
    19921 aacaccaata accattcttt tctggatttt gttgcagaat atcttggcaa aaaagcggct
    19981 ttcatcactg gctggacgta ttggttctgc tgggtatcga ttgcaatggc cgatttaaca
    20041 gccatcggaa tgtatgtacg ctactgggcg cctggtgttc ctcagtggct tcctgaactg
    20101 attgcattag gtcttcttct ttgcttgaat atggtggctg tctcattgtt tggtgagtta
    20161 gagttttggt ttgcattgat caaagttgta gcgatcattg cctttatcct cgtaggagct
    20221 tatatgatcc tcacccacta tacgacagat attggcacag ccagtatcac gaatctatgg
    20281 tctcatggcg gattctttcc aactggtgca aaaggattta tcttagcttt ccaaatggta
    20341 acctttgctt ttgctgggat agaattagtt ggattagtcg ctggagaaac agaaaatcct
    20401 gaaaaagtgt tgccggaagc tatcaataat attcctatca ggatcatctt attttactta
    20461 ggatctcttt ttgtcattat ggcaatctat ccatggaaca gcttgaatcc agataacagt
    20521 ccatttgtag aagtattttc ggaaattggg atcacgattg ctgcttcctt gatcaattta
    20581 gtcgtattaa gtgcagcagc ttctgcctgc aacagtgcaa tatatagtac aggacgtatg
    20641 cttcgttctt tagcgcaaga aggcagtgcc cctaaaaaat tcaaaaagtt aacaacacat
    20701 catgtgccag ggaatgcttt gacattttct actatcgtca ttttcatttc tgttatcttg
    20761 aattacgtga tgcctagtga agtattcaca ctagtaagca gtattgccac tacttgtttc
    20821 ttgtttatct ggagtatgct tgtctacacg cacatgaaat atcgtaaaag tatcctcggc
    20881 aaaaaagctc attcatttaa aatgccgttg tacccattta gtaattatct ggtatttctt
    20941 tacatggcct ttgtgtgtgt cgtcttgttc ctaggaaaag atacgagaat cgctttatta
    21001 ctaacacctg tgtggttctt gcttctatta ctaatctatc atatgaaata tgaacgtaag
    21061 aagtaagaaa gtagttgtga cagaagtggt cagcttcgag aaataagaag gaatttacga
    21121 aaattgcttc ttaaattttt gtgaaatttc ggcttatttc ttggagataa aagcttctgt
    21181 cccagcctct tttctatttc cccggaaaca accgctgata ataggcatct gcttttttat
    21241 aggaaaaaat ccaaatacca gatacaaaaa aacgtccgaa taacccgatc aacggtacaa
    21301 aaaagacacc ggcaatcaag cataagttaa tcatcatgga gataagactt cgacggtcct
    21361 ttgacaaaac tctcacgaca tgggaatctg gtttatttgc tttcatgatt tgcctcatca
    21421 agataccaaa agaaaaactc cacatcgtgt atactaagac ataagccatc tcaggccaaa
    21481 aagcttcagg gttacgcccg acccaactag taacagaagg acataaagtc agccaaaaga
    21541 gcaaaaagat attcgaccag accactcggt aattaattcg ttctgccatc tgaaatatac
    21601 gatgatggtt cacccagatc accgcaacaa atataaagct gatggtataa gctaataatg
    21661 tatttcggat gacccataaa gaatgaaagc tagatgtatt agggatcttg atctctaata
    21721 caataactct caaaacaatg gctaccactc catcagtaaa tgcttctaat ctcgactttg
    21781 tcacgatgat tcctcctcag atgattcagc gcttttattt tatcacttac gttattaaat
    21841 aaccatcgtt ttatataggg aattttctga aaattgttgc atatttttcg aaattttgtt
    21901 acttttaaaa aaaggcggat tttataatta acttagccat ttggaaataa aaaaacgcca
    21961 cgtgaattcc atgttatatt gaagttacca caactctcaa tagacaagga tgaattcaca
    22021 tgacgcaaaa ccatgataac acagtttcac gcaagggaaa acacctaacc tactcagaac
    22081 gttgccaaat cgccatcctg aaaaaggaaa actattccaa ccgtcaggtt gcggatgtcc
    22141 tgggctgcgt gccgcagacc ataaacaacg aaatcaaacg cgggaccgtt actcagctta
    22201 accgccagaa tcagaacggg aaggtctacg actattatca tgacgtctac gacgccgatg
    22261 ccgggcaggc ggcctacgag aagaaccgct tgaactgcgg cagacggccc ttatgggccg
    22321 acacggacgc cttcattgaa tgggcggacg acatgatgct gttggaaaaa tggtccccgg
    22381 acgtggtggt gggctttgcc agaaaacacg aattgttcga cccggccatt atccctggga
    22441 ccaccaccct ctatcagtgg atcgaccgtg gcatcatgaa aacgaagaat atggacctgc
    22501 tagaaaaact gtcccgcaaa ccgaaatcgt cccgtcatgg caaccgcccg aataaacggg
    22561 tgctagggaa atccattgaa gagcgcccgg aggcggttgg tacccggaaa accttcggcc
    22621 attgggaagt cgacacggtc gtaggaaaca agaccaagtc ggatgccgtg ctgctgacgt
    22681 tggtggaacg gcagacacgc ttcgaggtca ttctgaagct ggccgggaag gatgccgaat
    22741 cggtcaacca agcggtccga cagctgagag aacgggctgg tgcgtacttc ggccagctgt
    22801 tcaagacggt tacctcggac aacggctcgg agttcgcggg actgcacgat gccttgcagg
    22861 atgtggcaaa catctacttc agccacccct atgcttcctg ggagcgcggg acgagcgaaa
    22921 accaacacaa gctgattcgc cgtttcatcc ccaagggcag cccaatcggc aacgtgagcg
    22981 aaaaccaaat cttgcggatt cagcgttgga tgaacgatta cccgcgaaag attttgggct
    23041 atgcaacgcc gcatgacacg ttcgtccagg catttaggca ggaacggttg acggcttgac
    23101 acgtgggccc ttgacaacga gcctccctcg gcatggcttg tgtctggaaa gctggccggg
    23161 gccagccagt cgggagacta ccatgcctca gctcattgtc aagggcccac tcgattagaa
    23221 aaattagacg gttggtggta acgagcaacc gggtcaccat gggtggctaa cttaaacttg
    23281 aaatttacga cttttaaaaa aaccgtaaag gagttatgta tgacaaaaaa attatcattt
    23341 aaagactatc tttttatagg ctccatgctt ttcggtctat tttttggtgc tggaaatctt
    23401 atctttcccg ttcatttggg tcaagaagca ggcgctgcta ccttttgggc gaatctaggt
    23461 ttcttggtta ccggtatcgg tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa
    23521 agctcaggtg tatatgaatt agcaaaacgg ataaatcaaa catatgcgat ggtttttacc
    23581 atcttgcttt acttagttat cggaccgttt tttgctttac ctcgccttgc aaccacatct
    23641 ttcgagattg gtttagcacc atttatcgat cctagcagac agacgctata tctagcaatt
    23701 ttcagtattg tattttttgt gctggcttgg tggttttcaa gaaaaccgac aaagatatta
    23761 gattatgttg gaaagttcct gaatcctgca tttttggttt tattaggtgc tttgcttctc
    23821 cttgcttttt tgaatccact aggttctgta aatcaagcgc ctattcagcc aaattatcaa
    23881 gagcatgctt ttttcacagg gtttactcaa ggatataaca cattagatgc gcttgctgct
    23941 ttagcatttg ggatcatcat tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct
    24001 gaaatcgcta aagacacgat caaatctggt gcgatcagca ttatattgat gggaatcatt
    24061 tatactttgc tcgcttattt aggtgctatg agcttaggta gctttgctct aagtgaaaat
    24121 ggcgggatca cgctggctca gattgctgat cattatttag gtacttatgg cagtatctta
    24181 ttagcattta tcgttatatt agcttgcttg aagaccggta ttggtttgat tacagctttt
    24241 gcagaaacat tcacagattt gtttccgcaa agaaattacg cattctttgt tgcacttgct
    24301 agtatccttc cttgtttagc ggcaaacgta ggcttgacga atatcattca attttcgttg
    24361 cctgttttga tgttcatcta tccattagca atgacactga ttttactagt gttagttggt
    24421 cctttgttta agcagcgtac ggctgtttat cgaatgacta cttattttac attgattgct
    24481 tcgatttttg atgggttgaa cgcttgccca gaaactatca aacaaacacc tattgttcaa
    24541 aatcttttat atgttgcgga aagctacttg ccgtttttca aattggggat ggggtggatc
    24601 gtaccagcag ttatcggttt tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa
    24661 gtagcagatt gataaaagag gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa
    24721 ttttgaaaaa tggcttctca catttttgca taaatttgac ttaataccga gaaactgact
    24781 tttgaacacc gtttattgag aggtcgtgaa aaagccgctt agtttcaagt attaagaaat
    24841 attttgtgaa aatggcttct cacatttttg cataaatttg acttaatacc gagaaactgg
    24901 cttttgaaca ccgtttattg agcgtctata aactgacctg agtattagag aaacaaaacg
    24961 gcaaagtagc tccatatact ttgccgtttt gttttgaact aataccgaag agaagctgat
    25021 caaacaacat ttcttttata atatagattt tagacatata tatgatataa aaatagtttt
    25081 cgcaaaaaaa
//
LOCUS       DACGDM010000031        23830 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.031, whole genome shotgun sequence.
ACCESSION   DACGDM010000031 DACGDM010000000
VERSION     DACGDM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.031"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(54..788)
                     /locus_tag="IXR05_001391"
     CDS             complement(54..788)
                     /locus_tag="IXR05_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4259903.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="IXR05_001392"
     CDS             1115..1525
                     /locus_tag="IXR05_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAQ4259904.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="IXR05_001393"
     CDS             1518..2219
                     /locus_tag="IXR05_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAQ4259905.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="IXR05_001394"
     CDS             2219..3805
                     /locus_tag="IXR05_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4259906.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="IXR05_001395"
     CDS             3824..4045
                     /locus_tag="IXR05_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAQ4259907.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="IXR05_001396"
     CDS             4042..4803
                     /locus_tag="IXR05_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAQ4259908.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="IXR05_001397"
     CDS             5183..5692
                     /locus_tag="IXR05_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4259909.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="IXR05_001398"
     CDS             complement(5767..6306)
                     /locus_tag="IXR05_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAQ4259910.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="IXR05_001399"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="IXR05_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAQ4259911.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7373..8170
                     /locus_tag="IXR05_001400"
     CDS             7373..8170
                     /locus_tag="IXR05_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAQ4259912.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8198..8833
                     /locus_tag="IXR05_001401"
     CDS             8198..8833
                     /locus_tag="IXR05_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAQ4259913.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="IXR05_001402"
     CDS             8853..9626
                     /locus_tag="IXR05_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4259914.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="IXR05_001403"
     CDS             10034..10831
                     /locus_tag="IXR05_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAQ4259915.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="IXR05_001404"
     CDS             10809..11222
                     /locus_tag="IXR05_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259916.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="IXR05_001405"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="IXR05_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4259917.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="IXR05_001406"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="IXR05_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAQ4259918.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="IXR05_001407"
     CDS             15999..16559
                     /locus_tag="IXR05_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAQ4259919.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="IXR05_001408"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="IXR05_001408"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAQ4259920.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="IXR05_001409"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="IXR05_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAQ4259921.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="IXR05_001410"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="IXR05_001410"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAQ4259922.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="IXR05_001411"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="IXR05_001411"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAQ4259923.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAIEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="IXR05_001412"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="IXR05_001412"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAQ4259924.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="IXR05_001413"
     CDS             21906..22484
                     /locus_tag="IXR05_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4259925.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="IXR05_001414"
     CDS             22536..23018
                     /locus_tag="IXR05_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAQ4259926.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="IXR05_001415"
     CDS             23135..23509
                     /locus_tag="IXR05_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259927.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4285 c         5114 g         6649 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcacccggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatagaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaata atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagtttt
//
LOCUS       DACGDM010000032        23077 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.032, whole genome shotgun sequence.
ACCESSION   DACGDM010000032 DACGDM010000000
VERSION     DACGDM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.032"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            102..2543
                     /locus_tag="IXR05_001416"
     CDS             102..2543
                     /locus_tag="IXR05_001416"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAQ4259928.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(2873..3577)
                     /locus_tag="IXR05_001417"
     CDS             complement(2873..3577)
                     /locus_tag="IXR05_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259929.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(3764..4009)
                     /locus_tag="IXR05_001418"
     CDS             complement(3764..4009)
                     /locus_tag="IXR05_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259930.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(4026..4877)
                     /locus_tag="IXR05_001419"
     CDS             complement(4026..4877)
                     /locus_tag="IXR05_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4259931.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            5043..6047
                     /locus_tag="IXR05_001420"
     CDS             5043..6047
                     /locus_tag="IXR05_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAQ4259932.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(6288..6644)
                     /locus_tag="IXR05_001421"
     CDS             complement(6288..6644)
                     /locus_tag="IXR05_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4259933.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            7012..8199
                     /gene="tuf"
                     /locus_tag="IXR05_001422"
     CDS             7012..8199
                     /gene="tuf"
                     /locus_tag="IXR05_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4259934.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(8387..10978)
                     /gene="mprF"
                     /locus_tag="IXR05_001423"
     CDS             complement(8387..10978)
                     /gene="mprF"
                     /locus_tag="IXR05_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4259935.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11004..11723)
                     /locus_tag="IXR05_001424"
     CDS             complement(11004..11723)
                     /locus_tag="IXR05_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4259936.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            12043..12564
                     /locus_tag="IXR05_001425"
     CDS             12043..12564
                     /locus_tag="IXR05_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAQ4259937.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            12623..13483
                     /locus_tag="IXR05_001426"
     CDS             12623..13483
                     /locus_tag="IXR05_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAQ4259938.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            13590..15983
                     /locus_tag="IXR05_001427"
     CDS             13590..15983
                     /locus_tag="IXR05_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4259939.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            16165..18006
                     /locus_tag="IXR05_001428"
     CDS             16165..18006
                     /locus_tag="IXR05_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAQ4259940.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            18030..19139
                     /gene="rpoD"
                     /locus_tag="IXR05_001429"
     CDS             18030..19139
                     /gene="rpoD"
                     /locus_tag="IXR05_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAQ4259941.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            19359..21458
                     /locus_tag="IXR05_001430"
     CDS             19359..21458
                     /locus_tag="IXR05_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4259942.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            21654..22517
                     /locus_tag="IXR05_001431"
     CDS             21654..22517
                     /locus_tag="IXR05_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4259943.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            22622..>23077
                     /locus_tag="IXR05_001432"
     CDS             22622..>23077
                     /locus_tag="IXR05_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4259944.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEK"
BASE COUNT         7771 a         4038 c         4810 g         6458 t
ORIGIN      
        1 tttaaggatt gttaaaattt aatcttagaa aaaaataact ggaacaagag ctatttgttt
       61 ttacagcaaa gaatggtata tttttgtagg aggtggctta cttgaaagaa gtcgttatga
      121 tagatgctgc aagaacgccg ataggaaagt atcgcggaag tttaagtcca tttactgcag
      181 ttgaattagg cacacttgtg actaaaggat tattagataa aacaaaactg aaaaaagata
      241 aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca
      301 gacagattgc tttgaacagc ggtctccctg tagatgtccc agcaatgacg atcaatgaag
      361 tttgcggatc tggtatgaaa gcagtgatct tagcacgcca gctgatccaa ttaggtgaag
      421 cagaacttgt gatagccggc ggaacagaga gtatgtctca agcacctatg ctgaaacagt
      481 atcagtcaga aacaaatgaa tatggtgaac caatttccag tatggtcaac gacggattga
      541 ctgacgcatt ttcaaatgca catatgggat taaccgcaga gaatgttgca acacaatttt
      601 ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg
      661 ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt caagatttct gatgaagacg
      721 tgttatctga ggatgaagca gttcgtggaa atagtacatt ggaaaaactg ggcacgttac
      781 gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa tgcttccccg ttgaatgacg
      841 gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga aaataataat ctgccttatt
      901 tagcaaccat caaagaagta gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc
      961 caatcaaagc cattcaaaaa ttgacagata gatcaggaat gaatttatca acaatcgatc
     1021 tttttgagat caatgaagca tttgcagctt cttctatcgt agttagccaa gaactgcagt
     1081 tagatgaaga aaaggtcaat atatatggag gagcaatcgc attaggccat ccaattggtg
     1141 caagcggtgc acgtatcttg actacattag cttacggatt gcttcgtgaa cagaagagat
     1201 acggtattgc ttcattatgt attggtggag gtttaggctt ggcagtcttg ttagaagcga
     1261 atatggagca aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg
     1321 aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg ttgatttttc
     1381 aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa gtgagtgaag
     1441 tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa aaatggattc
     1501 cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca aaaatctgtg
     1561 gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa
     1621 aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag ctgattcttt
     1681 gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa gatatctcta
     1741 ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta gtggatgtaa
     1801 aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca aacaagttac
     1861 gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt gctacagaat
     1921 cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac aaagaaatcg
     1981 gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt gacccttacc
     2041 gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg gcagctacag
     2101 gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga aatggattat
     2161 accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa ctaacggtgc
     2221 ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca aaagcatctt
     2281 tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct gcagtagggt
     2341 tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa aaaggccaca
     2401 tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag gaaatcgagc
     2461 aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct atacaaatat
     2521 tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag caagatttac
     2581 agttatttta tttactgcag atcttgcttt tttctctatc agaaaatatg tttattatta
     2641 gaatttttta tagttaaggt taggcatctt aagaaatcag gcaactccaa gatatcttca
     2701 ggtagaagag aagtcgccta acattgtagg atcataggtg atttgttgga caggtcaagc
     2761 tgatatttga gcctgatgtt agaaggaatt tctttttact tgctgtagaa attattatat
     2821 gactaaaaag gctgggattt taaatcccag ccttttatga caaatagaat ttttatcgat
     2881 cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat caaagtcaat ttgactttgt
     2941 atttccgttc gagtgctttt tcgataacga actcattttc agtagtcata gaaatagttg
     3001 ctaatttacg aggttcatca gcattttttt cattaataac tacttcatgt tcattttgtt
     3061 ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa cttaaagcgg
     3121 cattcgtatc agttgagcgt gtattttcag ttgtgtccgc ttttggtttt tccgtttttt
     3181 cttctggcac actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc gcagttggtt
     3241 catcgttttt caatcgttga tcattccagt aagacacgat ttcaataaga agattgtcac
     3301 ggaatcgttc gaaaatcccg ttttctcctg aacgaattct ctttaataca gtattgaagt
     3361 tgtcatcgat tggcacgttg atccgtgtat cttcatttgt tttcccagct aatccgatcg
     3421 ttaagatttg acggtttttg ggatcaagca tgacttgtaa cggcaaacca taacgtcgca
     3481 agctctcttc ttctagagaa cggaataatt gtcctcttac accatccaat gaaggacgga
     3541 attgatttaa taatttttgt ttctgttttt tcttcatatg ttctctcctt cgctcatacc
     3601 ctttcgatta taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa aacttgcgta
     3661 tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga aaaataaaaa
     3721 atggaacgga ttatgtatat atacataatc cgttccattc tttctatttt ttcggtatca
     3781 aggcaaaaac aggtagttca ggtgaataaa tgacttcatg ttcgtgccag ggtttgacca
     3841 ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt gtccagtttc
     3901 ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg gaatgaaaag
     3961 tctgggtaac ttcttccgag agagaattca agcgttcgat tggatccata aaatcacctt
     4021 tcgacttaaa attgggtagt atctgggtct tttgctttgc cgactacacc atctaactga
     4081 tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa ataattcagt attttctttg
     4141 attctgcttg gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag cgaccaacgc
     4201 aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat ttcaggcaca
     4261 tcgaagattt taccagtgcc taatggacta tatgcttcga ggatcatatc atgttttttt
     4321 gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa ggaaaacttg attgaccatc
     4381 ggcataattt ttgctgtttt tgctagtgta tctagatggt ggggtaagaa attgctcaca
     4441 ccgattgctt tgattttacc tgcttcatac agttcttcaa atgctcgcca tgtatctgca
     4501 tttgcttgtt cccaattatc acgaaaagca acagggtttg gccagtggat caaaaacaga
     4561 tctaaataat ctgtttggag cttcttcaat gattcttcaa aagaagacat cacaagttca
     4621 tagctgtggt ttgcattcca taattttgtt gtcaagaata tctcttctct aggaattcca
     4681 ctttccttaa tcgcttggcc gacgctttct tcattcttgt atccttgggc agtatcgata
     4741 tggcgataac ctgcagccag cgcttcttta acagaggaaa cagcgacatc cccatcaggt
     4801 gtttgccatg tgccgaatcc tactaccggg atttcgtaac catttgatag acgataagtg
     4861 cttgttaatg aattcatact ttcagctcct tttttattcg ttcaactata agtgtagcgc
     4921 atttttcgaa aaaaagaatc cattttgttt ctactcttga aatttttgtt taaaagaaaa
     4981 tgattttgat tctggtattt ttgatttttt ttccgtaaac taagacagaa gggaatgaga
     5041 aaatggatat ctatttaaaa aaagcaattc tgcatattat tgacagagaa actggttctc
     5101 cagtcttttc acaaaaagag ctggatctga caaaagaata tattcgtgat tttcttcaaa
     5161 agaagatcca aaaaatctct tctgctcaaa caaaaactgg acaactagca gaagaaagca
     5221 tgatcgttga atcacttaaa atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg
     5281 ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc acctagtgca gatgtatttg
     5341 ttgtcttgta tgaattagat acagtgatgt acttatcttt attgaaagtc aattatcgtg
     5401 aggcttacac tcactttgtt gaagcagacg aagcagggat cgacaaccgc ttgattttga
     5461 atcgagcaat tctaggggcg aaaacacaaa aagcagatga agcattcgct gtgaatttga
     5521 ctgattggac ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt
     5581 atttttctgg aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag
     5641 tgatccaaaa agtagccaag catcttggaa aaaaatttga gacagaagaa tttgatatca
     5701 tggctgattt gaaagaagct gtctatgata cgatagaaga aaaaggtcgg ttggatcatg
     5761 agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct tttaaagaag
     5821 aagtacaaga gcaaggattt gtcccagaag cacctcctgt aaaagaagta caagaaattt
     5881 ctgagaaaaa atttggaaaa caaaaattca agctatcaaa cgggatcgaa ctgatcgtac
     5941 cagtagatgt atatcgcaac ccagatttga ttgaatttgt gaataatccg gatggtacga
     6001 tatccgtgat gatcaaaaat gtggatgaag tattgaatcg tttataaaaa tgactagaat
     6061 attaggtgtt caagtaccag tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa
     6121 agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt gtctcacgct
     6181 ctaaacacgt ataaacggcg gaagcagaag caactccttc ttatttcttg gagttaaacg
     6241 cttctgtccc agcctctttt tatctaataa aattttaaga ccatttacta attatcgatt
     6301 ttttctgccg catttttagg cacttcagaa gcctttattt cttcccagct taatacacct
     6361 ttacgaggat tgactttgag tttaagatac gcattcatct ttaatggatg ttctctttct
     6421 tcgcgaagcg tcacctgttt tttttcacca tctttattat aagccgcttg cttgtaggta
     6481 taagtcgtga atttctctcc gttatctgct tgggtagctg acatttcgcc attcgtcgtg
     6541 atttttgtat aataagcttc gccgccgtaa aaataatgat aagctgcaaa acttccgccg
     6601 agaaatatgc ctaaaacgac aagtacgcca attaattttt tcatgtactt cacctctttc
     6661 cttattatta acgaaataga agatttcgtc tattgaaagt tgttggcaac agctgaattt
     6721 taaacttttc ctcattttgt tcttattgct tcaaaagaaa gttaaggact atcttgaagt
     6781 ttttctcaaa aaacacattt ttttatttat aaaaggtact tttttcgcgt ataagacaga
     6841 cgagtgctct tagttgactt tgaccaatat tgacgtataa taagcttagt tcgaatctta
     6901 caaaaagtaa gtcggacgta ttctttttga tttagtcaaa aaaagactat aataaaaagg
     6961 tgagagctga aatttttcag tgatctatat tatttaggag gtttgtaaat tatggcaaaa
     7021 gaacattatg acagaagtaa accacacgtt aacattggta cgattggaca cgttgaccat
     7081 gggaaaacta ctttaactgc tgcgatcact acagtattag gcaaaaaagg cctagcaaat
     7141 cctcaagact atgctagtat tgatgcagct ccagaagaac gtgaacgtgg gattacgatc
     7201 aataccgcac acgtagaata tgaaacagaa aaacgccact acgcgcatat tgatgcacca
     7261 ggacacgcgg actatgtgaa aaacatgatt acaggggcag cacaaatgga tggtgcaatc
     7321 ttagttgttt ctgcaactga cggtccgatg cctcaaacac gtgaacacat tttattgtca
     7381 cgccaagttg gtgtaaaata cctgattgtt ttcttgaaca aagttgattt agtcgatgat
     7441 gaagaattga tcgatttggt agaaatggaa gttcgcgagt tattgagcga atatggtttc
     7501 ccaggcgatg acactcctgt gatcaaaggt tccgcattaa aagcattgca aggcgatcca
     7561 gatgctgaag ctgctattat ggaattgatg gatacagtag atgaatatat cccaacacca
     7621 gaacgtgata cagataaacc attactattg ccagtggaag acgtcttctc aattacaggt
     7681 cgaggaactg ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg tgatgaggta
     7741 gagatcgtag ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt agaaatgttc
     7801 cgtaaaacgt tagattacgg ggaagctggg gataacgtag gcgtgttgtt acgggggatc
     7861 caacgtgacg atatcgaacg tggacaagta cttgctaaac caggttccat tactccacat
     7921 acaaaattca aagcagaagt gtacgtgttg acaaaagaag aaggtggacg tcatactcca
     7981 ttcttcaaca actatcgtcc acagttctac ttccgcacaa ctgatgttac aggaacaatc
     8041 acattgccag aagatacaga aatggtcatg cctggtgaca acgtgacgat tgatgttgac
     8101 ttgatccatc caatcgctgt tgaaaacgga acgacattct caattcgtga aggcggacgg
     8161 acagtaggtt caggtatcgt tacagagatc gaagcataag aaacgcgact cgaatatttt
     8221 ggtaatgaaa aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt ttggaccgct
     8281 ctttgttctt caattgtata agaagagatt gtagaagcat gaactttcgt tttacttcag
     8341 tctcttttat tcatcatgag agtgttcatc tatcggtatg cagtttttaa tactttcttc
     8401 gtatccattt tttcaaacca cttattctac cttgtgtctg ctcaactggc gcattatcaa
     8461 taatcagcaa agcaatcata acatatgcaa tccaactatc tctagaatat agagtataac
     8521 gtgagaccca gtttgtagcg tacttgcttt tatattctct taatccatgg aaagaataaa
     8581 aatgagaacc aaactcgtaa accaagtatg caatcctttc ctgtaaaaaa ctctttctgg
     8641 aagttccgac atttgaaaga ggggccatcc ctaaattgaa ccattggata tgttcttctt
     8701 tcatataggc aaacaaatgc aagaacaaga aatccatact gccagaaggt gcttttttag
     8761 aatcatatcg catcagatca atcgttccta ctttattgtt cgtgtaagta ggcatgatcg
     8821 ttgcaaaagc gacaatttct tcttgggtat ttttgacaac tgcaataggc gctctttgta
     8881 gataatcttc agagaaaaag cctaaagaaa accctttttc ctttcgtgaa cccaaccaat
     8941 tatcagagat atttttgaaa gtactcattt gctcagtaga aaatggtggt tgtaagacat
     9001 caaatgtaaa tccttctcgt tcgatccgat tcaagacagc acgagtgccc ttcatttttt
     9061 tccctgaagt tgtaaaacta ttcaggtcta cataagcttc ttcccccatc ttaatgaaat
     9121 cgtagccgaa ttcatgcaaa atcataacaa tctcttcgct tgtttcgtag aaaactggta
     9181 aatagcatag tcgatctgtt tcttcgataa aagcttcgat tgcttctgga aaatcttctt
     9241 tcttaccaga aggatcaccc attacaatac atttattatt gaagcaagcg aattggagaa
     9301 gaacagttgg ttcaccgtct ttttcatagg caaacatccg cttatctttt aagaagatca
     9361 attgactatc ggagtttcct ccataagttg taaggatctt cagggccttt tcttcattaa
     9421 aggcttcgcc aatctgtttc ttttctcctt gaaggaaatg aacaaataga acgatcatga
     9481 aactaacagc gatgatggcc aacaatcccg aaaaccaaat cttttcagaa ggaaataaga
     9541 aaaaggaaat aaaatggtga cgccgatgag ggaaatccgg cagattgtat accccaataa
     9601 cgatgtaaag caaggacagt gcaccaataa tgattccatc gatcgtacgc cactcccatg
     9661 aatagatcaa ttgttcccga aataattcgt ttttagaagc aagaatgatc agaagcagaa
     9721 tagacaagaa aaccaccggt gtgaaactaa aatcacttaa taaaacataa agtaaagcta
     9781 gaacaatcaa gaagattgta ggcaaatatg ctcgtttcac acgtgctgcg atccctctgc
     9841 ccataatgat taaaagaaat cccaatagta tactaggaaa ttggataata aaatgaaatt
     9901 tcaatgggtt caaactatga agccagcgaa actctgtaaa agcttgcggg atagtggcag
     9961 aaagtactag catgattcca gaaaagtata ataagacaac cacgatttta tgcgcaattt
    10021 ctgttgctaa ttgtttaggg ataccagaat aacgctgatc aaaagtggaa ccgatatttt
    10081 tgaagaaaaa gacgattcca atcaaaaacg gaatgatgta gtagaacagg cgatagagca
    10141 agatccacac aacgactatt tctcttggca caccaatagc ggacaacccg ataatcatca
    10201 ttacatcgaa actcccaatt tctcctggaa tcatagacac gattcctatc actgaagcag
    10261 caatgaataa tggaattgtt tgccacagat caatccggat ttccattaaa taaccaacag
    10321 aaaggaaact aaacaggaca ccggtccatt ccaacaatga aactagcaat agctgtcctt
    10381 gagttttaag tgaggtacca ccaaggaatc ctttcttttt gaaagtagta aataaaaaga
    10441 cgacaggaaa atatagaccg ccgccgatca accatatcca atattgcttc aaaaaaggag
    10501 caactggcgt gaagactaca agtaaaaaag aaagcagact gtaaatagaa agtccagcca
    10561 tcaaaaacaa gaaaactttc gataatgctt ggatcacgtt tctgctctct ttcttttgtc
    10621 catatagttc agagcgaagc cccacactaa caaacccgcc gaaaccggca atattgttga
    10681 tcgtattgat cagccagctt gtctcaaaca ggtaacgagg attctgcttt tgttcaagca
    10741 tccgattcaa aataatatca taaccaacca taggtaacac agagataaga ccaatcaata
    10801 gcattagtcc gcttttccat acaggtatag tggcaaacgt ttctcctaat tgctggatag
    10861 atagagtttt accgatggac atcaattcac cgacaataat gacaatgaca gaaatcaaaa
    10921 agattgtttt gaacagtcct aggtggtttt tcagccattg tatggtattt tttaacaaat
    10981 aaatcacctt ctattcctaa tagttatgtt tcagaaagaa attgaagaac ttctcgattg
    11041 aagcgttcag gatcttttct agctaattca tgtccttgtt ctttcacaag cacaaaggaa
    11101 gcttttggta tagttttagc tatatacaaa gaatgtttta gcttgattac atcttttttt
    11161 cccacgatga tcaaagtggg ggagttgatt ttttttaaat cattttctgt aagcccgatg
    11221 tcatgcagca aaagtttgat aactaaaaga tttttgcgaa gacttgggcg aaataaagag
    11281 agtaaccata cccatgcata atgaatatta ctgatgactc tggcagaaaa acgaacgcct
    11341 ttaacaagcg tgtttccaga atttaaaatc aatcgatgaa cttttttagg gaagctgctg
    11401 gcaaatacca gtgctagatt tgctccatca ctaaatccaa gaaaatctgc ctgatcgatt
    11461 ttttccagca acatgatcgt attcagatcc tcggccatta actgaaaatt caacatagat
    11521 gcttcgtttg tcgaacgacc atgtcctcgg ctatctacta gatacacggt atagtagcgt
    11581 tcgagtacag ggacctgttc tgaaaaaaag cggccgctgc cgtcattgcc atgcagtaaa
    11641 aagagaggga agccttgacc gctcttttca tagtaaattt cgctcccatc tggcattttt
    11701 gcatatttct tttctttttt cacataatca cctactgtgt aaagtataac gattatatca
    11761 gtcattgggc aattgttttt actgaaaaac aacgatcatt ttcgtaagat gtcaaaaaat
    11821 acaggaaaat tcattttttc ttaaggcgta cacagaaatc aaggaagaaa tagccaagaa
    11881 gataaagaaa tagtaagata aaaaaagatg tcaaaataac taggtgatga aatgaagcga
    11941 aaacgattat ctattatccg tattcttttt tacatgatca ttctgacggt tattggtgcg
    12001 gtgttgtttt tatgaggaag aacttatcgt tcggtaaaac gagtggaaag ctatcaaata
    12061 gaaataacaa cagctgcaaa aaattatcat atggaaaact acgagaattt gatcaaggcg
    12121 ataatattga ccgaatcaaa aggaaaaggg acagatctca tgcagagctc ggaaagtctg
    12181 catggagaag ctgagatcat tgataatcca gctgacagta ttgatcaagg tgtcaaatat
    12241 ttggcggaaa tgatagtaga agcaaagaaa caaggatgcg atttatggac agctgtccaa
    12301 gcatataatt ttgggaaaga ttatattgcc tatgtaaaaa atcatggcgg agaaaacaca
    12361 gtagaattag cagaagcgta ttctaaagat gtgctgagcc cacttttagg aaatgaggaa
    12421 gggaaacaat accgatattg gcggatccag tccttgcttt acaatggcgg ctatctctat
    12481 cataatggag gtaacatgtt ttatcctgat attgtcaaaa tgaatgaaaa aataatagag
    12541 acctatgaaa aagtctttaa gtaaaatagc aggaaatgtt caatcatgaa taaaattaaa
    12601 tgaaagaagg agtgcgcaaa tagtggaaaa aaggcaaaaa atggaaaatc aagaagtggg
    12661 gtacacaacc aaagactgga tgttacggtt tgtgaaggga atgtttatcg gttcaggatt
    12721 tatcttgcca ggagtcagcg gtggtgcatt agcagctgtc tttggcatgt atgagcggct
    12781 gatttctttt ttagcccacc ttacaaaaaa tttcaaagaa aatgttttgt tttttctgcc
    12841 tgttggtcta ggcggagtga caggcatctt tctactttct tttttagtca gttttttatt
    12901 aggtgcgtat gaaacaacga tattatggtt ttttgtcgga tgtatcgctg gaactgttcc
    12961 tgcgttatgg aaagaagcag ggaaaaaagg aagagatact tctgatgtga tcatcatggt
    13021 tgttactttt gttctggctt atttgttttt attatacggc gctcaattat ttgacgggca
    13081 agtcgatcag aattttggaa catggctgat tgccggcgga ttgattggtt tgggtatgat
    13141 cgtcccagga ttgagccctt ctaatttttt ggtgtatatg ggattgtata aagcgatggc
    13201 tgacggattt aaagaagtac gacttgaagt gattgtgccg atcggaattg gtgggattct
    13261 ttgtgttctt ggattgtcaa aaatcatgga ttacattttc tcaaaggcat atagcaagct
    13321 attccatttc attttaggtg tagtttttgc ttcaacgatt atgatcattc ctaccgatta
    13381 cgcgggattg ggagttgctg gggtactagc ttgtcctgtt ctttttatag ccggtacagc
    13441 actaggttgg tggatgagcc gtttggagga acaatataag taaagataga ttgataataa
    13501 aaacagcaca cgggtgattc aaacaaaaag gttggcatct tttttgtaaa atcattcgtg
    13561 tgtttttcta taaattttat aaaaacaagt tgtttttaat cttggaacac gctagactta
    13621 aacacgtgat tatttttgaa agttggcgga aaatggagaa aaagaaaatg aatggactta
    13681 cacagcaaga ggtagttcag aaaatggctt ctggccagca aaatgactac caggaagatg
    13741 catcaaaaag tacaaaacaa atattcagcg ataatatatt gacgttattc aattttctga
    13801 actttggtat tgggatttgt ctgttatttg taggtgcgta ttccaacatg gcgtatttag
    13861 caattattgt cgtcaatatc gttattggaa tttatcaaga aatacatgca agaaatcttg
    13921 tacggaaatt atcgattgtt tcccaatcag aagtactagt gatccgggac ggtaaagaac
    13981 aatcgatttc tactaaagag ctggtattag gagatttggt aaaaatcgga gcaggagaac
    14041 agataccagc cgatttacag gttatatctg gacgggcaga agcaaatgaa gctcttttga
    14101 caggcgaatc tgatttgatt gtcaaagaaa ctggagctga attgctttct ggaagctttt
    14161 tgacaagcgg ttctgtcatg gctgaagtta tccgagtagg tgcagataat tatgctgtcc
    14221 gcttgactag cgaggcaaag actcacaaag ctattcgttc tgaacttgta gattcgattc
    14281 gcaaagtatc caaattcact agtttcgtga ttattccttt ggggatcata ctatttttgg
    14341 aagcactgtt catccgcgat gcttctatca aaatttctgt tattgcatct gcagcagctt
    14401 tgttaggcat gcttccaaag ggtttggtat tgctaataag tattgcatta acgacagggg
    14461 taaccaaact ggcaaaaaaa cgaatccttg ttcaagacat gtattcaatt gaaacgctgg
    14521 cccatgtcga tacattatgc ttggataaaa cagggaccat tactgaaggg aaaatgagta
    14581 tccagcgggt agaagcacta catccgctgt acgagaaagc catcccagaa attatgggga
    14641 cgtatctggc agaaagcagt gataacaaca tcactatgcg ggctatgaga gattattttg
    14701 agctttctaa tcggtatgat gtgacaaaca aagtcgcatt ttcttctgat cgcaaatggg
    14761 gcgcgatgga atttccagaa ctgggagtcg tgtacgtagg agcgcctgaa cgtttggtgg
    14821 aagaagatcg gcttccggac agtctaaaaa cagcccaagc gaatggctat cgcgtactta
    14881 tgttggggat cgctccaaat cagcaattga acgaagaaaa accagcattt gttgagccgg
    14941 ttgctctgtt tgaaatcgat gatccaatcc gaaaaaacgc tcaagaaaca ctagcttatc
    15001 ttcatgagga aggtgtggat ctgaaagtga tttctggaga caatcctttt actgtctcca
    15061 atatcgctag acgtgcagga ttaccgaatt atgatgcgta tgtcgatctt tctcaaatta
    15121 ctgaagaaat ggaagtgcga gaagctgctc atcgctatac ggtttttgga cgagtgagtc
    15181 cgcagcaaaa gaaattgctg gtaaatgaat tgaaagaaag cggcagaacg gttgcaatga
    15241 caggcgacgg tgtgaatgat gttttggcgt taagagaagc agattgcagc attgctatgg
    15301 cagaaggtga tggagcaaca cgtcagattg cgaatctggt attgttggac tctgatttta
    15361 ctacattgcc agaagtcctg tttgaaggac gccgagtggt caacaatgtg acgaaagtct
    15421 caggcatctt ttttatcaaa acgatttatt catttatttt atcgattata tgtgccgtta
    15481 cagcaattgg atttccgttt atccctatcc aaatcacgct gattgattta gcgattgaag
    15541 ggtatccttc cttcttttta tcttttgaac aagataaaag aaaaatcact taccgttatt
    15601 tgcctacagc acttattaat gctttaccaa atgccttgct tgtagtagtg aatatcattg
    15661 cggtgtatct acttggaaaa acattcgcat ggggaaatgc tgaaactact actttgatgt
    15721 attacttgct gattgggatc agttgcatgg cagttgtaaa agcttgttat cccttcaacc
    15781 cattgcgcat cttcctagca gtaacgacga tcgtagggat atatgtagct gcaatgctgt
    15841 tccatggaat tttggaagta aacttagggt tgggagagag cgtaggatac ttctttgtat
    15901 tcatgctcgt aaatattgtt cttcgagtat tgtactggaa ggctgatatt caaaatcagt
    15961 tactgaaaag agtagcaaat tgatgcttaa tgagatagaa atgtgttata cttgaaaaag
    16021 caatgaaata tgatacaatc aaacatgtat aattgtgtcc tttaaaatcg cactgatttc
    16081 agttagtgcg attttttacc ggttattctc ctgaaatatc ttctgttaaa cccaaaagat
    16141 atcaatagag cagggggtga aaaaatggct caacggattc ctcaagaggt tatcgaaaca
    16201 gtacgcagtc aaacgaatat cgttgaggtg attggacaat atgtccagtt gaaaaagtct
    16261 ggtaaaaatt acttggggct gtgtcctttt catgaagaac gtacaccgtc tttttctgtt
    16321 gcagaagaca agcagatttt tcattgcttt ggttgtggta aaggcggaaa cgtgtttact
    16381 tttcttcaag aactagaagg tctaagtttt ccagaagcag tggtaaaagt ggcagacttc
    16441 gaacagatac cgttagaaga tcaatggcgt cagcgtacta tagctgtcca aaatcctgaa
    16501 tctgctacgg ggaaactgat tgctgctcat gaaaaagcag cggaaatcta tcatcacatg
    16561 ctattgcata caaaagctgg acagccagct ttagaatatt tgcaaagtcg tgggttgtct
    16621 ttagaattaa ttgaagaatt caacataggt tttgcaccta atgagcgttc ttttcttcag
    16681 caagtattca agaatgaatc aatttcaaat gaattgttag aacgctctgg attgtttgtc
    16741 acgcatgatg atggccgtat gtctgatcgt ttttatcaaa gagtgatgtt tccacttcgt
    16801 aattctcaag gccagacgat cggtttttca ggacgctggc ttgcacctga aaaagggcag
    16861 gaaaaagatc agcccaaata cttgaatagt ccagaaacag aactgttcaa taaaagacaa
    16921 gttttattta atcttgataa agcaagaagc gatatccgga aaaacggaga aattttgttg
    16981 ttcgaagggt ttatggatgt gattgctgca tggcaggctg gtatcaaaac tggattagct
    17041 tctatgggga caagtctaac agctcaacag atccaacaaa tggaaaagct gacgaaagaa
    17101 ttggtctttt gctatgacgg agacaacgca ggttttgaag caaccaatcg agggattgaa
    17161 ttgcttcggc aaaacagtcg attagcactt tctgtcgtag tcgttccaga aaagcttgat
    17221 cctgatgaat atctccgtaa gtatggagaa gcatctttcc aagaattagt ggctcatggg
    17281 cgcgaaacag tctttacttt taaatcacgt tatttaaaac aagggaaaaa tttagataat
    17341 gaaaaagaca agatcgaata cctcgaagaa ttactagttg aacttagccg agttgtttca
    17401 ccaatcgaac aagatatgta tctatctcaa ctgtcaacag agtttcagat cggcagagag
    17461 acgatacaaa aacaactgcg cgatcttcga aggacaaatc agcaaaatcg tcaagaacct
    17521 caggaaagtc aacacactca ggttacgaga caagaaactg cacggaaaaa gagacctttg
    17581 acgcaagtag aaaaggcaga gcagattcta ttatatcgtg catttaaaga agtttctgtc
    17641 cgtaatattt taaaagaacg agaatttcag tttattcatg atgcatatgc agaagtttat
    17701 tttttattcg atgcatatgt ctcacaacat tatgaattca accttgcaga gtttttagac
    17761 tttttgcaag atgaaaattt aaggcggttg gtggtggaaa tcgaatattt accggtggca
    17821 gaagaaagtt cgccacgaga aatccaagac ttgctagatg tgatcagcaa atctggctta
    17881 gctgatgaaa taacattaaa aaaacaaatg cagcaagaag ccagacgaac tggaaacaaa
    17941 cagcttgagc ttgaattgac gattgaaatc atcaatttaa cgaaacagtt aaaacaagcc
    18001 aaatagctac tcaagggggg ccttctttta tggcaaatgg aacagataaa aaaacgtatg
    18061 aagcagcagt agcagctttc atcaaagaaa acaaacccaa acgacaagtt gtatatgatg
    18121 atttatccaa tcagcttgct acaccattca ctttgaatgc agatgaaatg gacaaattga
    18181 tccaaaagat tgaagacgca ggtatcagtg tggtggatga aaatggtgat ccatcaattc
    18241 acagcttgaa gagtgctgag aaaaaagctg aacaagcaaa aacagaagat ctttctgcgc
    18301 caaccggtgt aaaaatcaat gacccggttc gtatgtatct gaaagaaatt ggccgtgtct
    18361 cccttttaac tgcggaagaa gaagtagcgt tagcattgaa aatcgaagaa ggcgaccaag
    18421 aagcgaaaca gcgtctggca gaagcaaacc ttcgtttagt agtaagtatc gctaaacgtt
    18481 atgtaggacg aggcatgcag ttccttgact tgatccaaga aggaaacatg ggactgatga
    18541 aggcagttga aaaatttgac taccgcaaag gatttaagtt ttcaacctat gctacatggt
    18601 ggattcgtca agccatcact cgagcaatcg ctgaccaagc acgtacgatc cgtattccag
    18661 ttcatatggt tgaaacaatt aataaattga tacgtatcca acgtcaattg ctgcaagacc
    18721 ttggaagaga acctacgcca gaagaaatcg gtgcggaaat ggatcttcca acagaaaaag
    18781 tccgagaaat cttgaaaatc gcgcaagaac ctgtttccct tgaaacgcca atcggtgaag
    18841 aagatgactc tcacttaggt gatttcatag aagaccagga agcaacaagt ccagcagaac
    18901 acgcagctta tgagttacta aaagaacaat tggaagatgt actagataca ttgactgatc
    18961 gggaagagaa tgtccttcgc ttacgttttg gtttagatga tggccggacg agaacattgg
    19021 aagaagtagg gaaagtattt ggtgttactc gggaacgtat tcgtcagatc gaggctaaag
    19081 cattaagaaa attgcgccat ccttctcgtt caaaacaatt aaaagatttc ttagaataag
    19141 cgtggactat tgaccagaag agaaatcagt aaaactgttt ggtttatttt aaaagaaaaa
    19201 aagcttgaga ctacgcagtc tcaagctttt ttttctatag gaaggaaatt cattcattat
    19261 ttttaagtaa atcctaaaaa taagctattg gcgtgacgta tagaatatga tagattaaat
    19321 ggtagcgtaa acctagtaaa ggagccgatc gctaagtgat gaaaaaatgt ccaaattgcg
    19381 gatcgaaaaa aatggagcag aatactatct gtccagactg cggtcatcaa ataactgcag
    19441 aagatcagca aataaaagaa tcaattgaag aaacaaatac agatgcagct atgcaggata
    19501 aatcaactga agatgcagtc tttcctgata cagaattaaa cgatccaatc gaatggtcgg
    19561 aattgaaaga tttacctcta gaatctgtaa tggaattatt cgaaaaagca gaaccagaag
    19621 acgaagaacc acctgctcac gatcaagtaa ctaatataga gaaaaatgaa cagaagaaag
    19681 caactgttca tgagacttcg gaagaatcag gaaagaatca agaagaaacg cttgaatcaa
    19741 aacaaaaaag aagagtagct gaactgaaag aaatcgtcga taatgaggaa gaaaattcga
    19801 tactatccgc ttatatcaaa gcacatcgtg aagatacaaa agaagagcac gcgaaagagc
    19861 tgctcaaaat gatcagtgaa aaaattgcac aggaaaacaa agtagagcca gaaaaggaac
    19921 aagaaactga aaaagactct gatagagaaa acgccacagg taaagaaaca gtaaaaataa
    19981 aagacgtaaa aacggatatc acagaaaaaa ctgaagtatt tactgaaaaa caattagaaa
    20041 aggaaaaaac gaataaactg ccggaagcag agaaaaaaga aatactcgaa aacacagaca
    20101 aaaagtcaac agagcccgat gaaataaata gtgaatccga tgctgaaaat caatctgtaa
    20161 gcaaagaggg tactgatctt gaagcaaaaa tagaaaaaga agagaaccag cctaagctgt
    20221 ttgaagcaga agcgaaatca ataacaatcg tgccagatac tgaaaaaaca catcaagaat
    20281 caaacttaga aaaaacagat ccagataaag cgcaaaagaa aaaatcaaaa aaagtacctt
    20341 atctcgtttt agcagcagta cttctactcg gtggaggaag ctgggcttat tatgaccatc
    20401 atcaaaaagt agaagccgaa gtagcagcag aagcaaaaag acagcaacaa atggaagaac
    20461 ttcatgagaa acttgctgcc ttttatacag atgatcacca tcaatttatt cgtgcagata
    20521 tgattcatca agatttatca aaactaaaaa atgatttatc cagtcttaag aatgaaaaag
    20581 gatattcaga gttagaaaca acttaccaag atatccaatc taagatccga gatatccaaa
    20641 aagtgaatga gtggttcata gcacctgcca tcgtcgatga tcatctagca gatgacatca
    20701 agttgaaagc agataaagag atccaagcaa tcgaaacgga taacacagat tttggaaaat
    20761 tgattcaaca agcacaaaca gaagctaaaa atcaatatgc tgaattgcaa acagctaaag
    20821 aaaaaacagc tatagtcttt aaagacggaa aagtagtgga ttcagcaaca cgcgaccaat
    20881 acaagacggc aaaagaagca gtagaaaaag tgaaaaatac agatctatct gctcagttga
    20941 atgaacaatt gaaacaagta gataagatgc tcactgataa agagaaaaaa gaagaagagg
    21001 aaaagaaaaa agcagaagaa gcgaaaaaag cagctgaaga acaagcaaaa caagccgctc
    21061 aagcagcagc tgcagctcaa gccgctcaac aagctgcggt cgcacaagca gcacagcaag
    21121 aagcggcatc ctcgacccct tcctcttcaa actcagcgaa tcagccaatc aaatctgcca
    21181 gagcaagtga tattgccgat gcatctaatc cagcatggac gtgggcacca ggtgtccaaa
    21241 gcaaagtgat tgctacatgt atccaacgtg gatatatcgt tgaaggaggt tacagattag
    21301 aaaaagccag aatcgaaaat ggggaaggct attataatct atatgccact tcaacaaaat
    21361 ctgcattgat gaaaggcatt ggagaaagtg ctttgccatt ttacatcgta accatcaact
    21421 gtaaaactgg atggttcgga ggaaatggga gcaattaatt ttaggcaaat gaaagaggct
    21481 gtgagcctgc cgtttaacac cgtttattcg aaaaagggga gtatgacaca actgttgtca
    21541 tactcctttt ttcacctttc caaaccaagg ctcagctatt caagtagata acattatgtt
    21601 atgatagcaa agaaatgtat taagaaaacc tttcactata gagggagaaa aaaatgaacg
    21661 atttattagc aactatattt acaggtatta ttattgatga aaatgaaaaa aactactttg
    21721 tccaaaaaaa cggacaaacc tttggcttaa gcaaatcaga aggtgaacac aaaatcggtg
    21781 aagcagttga aggattcggt taccaaaatc aaaaacatga aaatcggatc actacacaaa
    21841 ttcctaaaag ccgtatcggt cattacgctt ttggaatcgt tactgctaca cgaaaagatt
    21901 taggtgcgtt tgtcgatatc ggtcttccag ataaagactt tgtcgtatct cttgatgaat
    21961 tgccgacaat gacagagcta tggcctaaaa aaggggatcg cttgatgatt tcccttagag
    22021 ttgatgcaaa agaccgtatt tggggcagtt tagcagatga aaaaatattc aaatctttaa
    22081 gcaaatatgg aacagaagaa atgaaaaaca aagatgtgat aggaacagca taccgcttga
    22141 aattaacagg tacgtacgtt ttaacggaag atttctatct tgggtttatc catccttctg
    22201 aacgatataa tgaacctcgt ctaggcgagc agataaaagg tcgagtgatt ggtgtccgac
    22261 cagacggtgt actgaatctt tcattgaagc caagagcata tgaagctata tcagatgatg
    22321 cacaaatgat tttaaccatt ttagaacgtt ctgcagatca gcaaatcaac tttacagata
    22381 aatcggatcc agaagaaatc atgaaagctt ttggtatcag caaaggagca tttaagcgcg
    22441 cattaggtaa tcttttgaaa caaggattga ttacacaaga aaacggtgtg acaaaactag
    22501 tcaaaaaatc taattgagaa tcccttgcat gtttttctta actagcttat aataatttta
    22561 attaacatag tgttatatct ttttttattt gtaattatta taaattgttg gggttgagta
    22621 aatggtcatg aatgctattt cggcgatgaa aaaaacaaaa cagcagctac atgaagcggg
    22681 gtttaagctg acaccgcaaa gagaagctac tctgcttgtg cttttggaaa atgagaaaga
    22741 gcatttatct gcagaagaaa tcttcttttt agtgaaaaaa aagagtccgg aaattggact
    22801 tgctactgtt tatcgaaccc ttgaaatctt gacagaattg aaaattgtcg ataaagtaag
    22861 ttttaatgat ggattagccc gttatgattt gagaaaagaa ggcgccaaac atttccatca
    22921 tcatttacta tgcttgaact gcggcacgat cgaggaagta gaagaggatc ttttacttga
    22981 agtggagcaa gtagtagaag aacgttatca ttttttagta aaagatcatc ggctaacgtt
    23041 ccatggaatc tgtcaggaat gctatgaaaa agaaaaa
//
LOCUS       DACGDM010000033        23061 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.033, whole genome shotgun sequence.
ACCESSION   DACGDM010000033 DACGDM010000000
VERSION     DACGDM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.033"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(105..560)
                     /locus_tag="IXR05_001433"
     CDS             complement(105..560)
                     /locus_tag="IXR05_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259945.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(714..1922)
                     /locus_tag="IXR05_001434"
     CDS             complement(714..1922)
                     /locus_tag="IXR05_001434"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAQ4259946.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNEGAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2034..2366)
                     /locus_tag="IXR05_001435"
     CDS             complement(2034..2366)
                     /locus_tag="IXR05_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4259947.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2514..3389
                     /locus_tag="IXR05_001436"
     CDS             2514..3389
                     /locus_tag="IXR05_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4259948.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSGELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3471..4052)
                     /locus_tag="IXR05_001437"
     CDS             complement(3471..4052)
                     /locus_tag="IXR05_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAQ4259949.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4058..5317)
                     /locus_tag="IXR05_001438"
     CDS             complement(4058..5317)
                     /locus_tag="IXR05_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4259950.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5319..6365)
                     /locus_tag="IXR05_001439"
     CDS             complement(5319..6365)
                     /locus_tag="IXR05_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259951.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(6600..6875)
                     /locus_tag="IXR05_001440"
     CDS             complement(6600..6875)
                     /locus_tag="IXR05_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAQ4259952.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(7118..8428)
                     /locus_tag="IXR05_001441"
     CDS             complement(7118..8428)
                     /locus_tag="IXR05_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAQ4259953.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(8610..9839)
                     /gene="rpsA"
                     /locus_tag="IXR05_001442"
     CDS             complement(8610..9839)
                     /gene="rpsA"
                     /locus_tag="IXR05_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAQ4259954.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(9974..10654)
                     /locus_tag="IXR05_001443"
     CDS             complement(9974..10654)
                     /locus_tag="IXR05_001443"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAQ4259955.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(10703..11338)
                     /locus_tag="IXR05_001444"
     CDS             complement(10703..11338)
                     /locus_tag="IXR05_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4259956.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(11404..12807)
                     /locus_tag="IXR05_001445"
     CDS             complement(11404..12807)
                     /locus_tag="IXR05_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAQ4259957.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(12794..13825)
                     /locus_tag="IXR05_001446"
     CDS             complement(12794..13825)
                     /locus_tag="IXR05_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259958.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            13856..14077
                     /locus_tag="IXR05_001447"
     CDS             13856..14077
                     /locus_tag="IXR05_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAQ4259959.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(14242..14979)
                     /locus_tag="IXR05_001448"
     CDS             complement(14242..14979)
                     /locus_tag="IXR05_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAQ4259960.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(15132..16472)
                     /locus_tag="IXR05_001449"
     CDS             complement(15132..16472)
                     /locus_tag="IXR05_001449"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAQ4259961.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(16709..18232)
                     /locus_tag="IXR05_001450"
     CDS             complement(16709..18232)
                     /locus_tag="IXR05_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAQ4259962.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(18610..19221)
                     /locus_tag="IXR05_001451"
     CDS             complement(18610..19221)
                     /locus_tag="IXR05_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4259963.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(19344..19469)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(19551..20267)
                     /locus_tag="IXR05_001452"
     CDS             complement(19551..20267)
                     /locus_tag="IXR05_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4259964.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(20273..20842)
                     /gene="scpB"
                     /locus_tag="IXR05_001453"
     CDS             complement(20273..20842)
                     /gene="scpB"
                     /locus_tag="IXR05_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAQ4259965.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(20826..21623)
                     /locus_tag="IXR05_001454"
     CDS             complement(20826..21623)
                     /locus_tag="IXR05_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAQ4259966.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(21593..21964)
                     /locus_tag="IXR05_001455"
     CDS             complement(21593..21964)
                     /locus_tag="IXR05_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4259967.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(21983..22870)
                     /gene="xerD"
                     /locus_tag="IXR05_001456"
     CDS             complement(21983..22870)
                     /gene="xerD"
                     /locus_tag="IXR05_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAQ4259968.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         6464 a         4926 c         3911 g         7760 t
ORIGIN      
        1 cttgtcacag tcccttattc tgaataaacg gtgtggaaga gacagcctat cagtagtaat
       61 aagacacatc tctttcacag cctcattttt gcgtaaaaat cgatttattc gaaaaattcc
      121 ccgtatacat cttctacacg ttgatctgga ttgatcacga tatacaagtt acctgttttt
      181 tcgctgattt ttgttgattg atattgattg tctaatcctt ctgttccttt atctagatat
      241 gggaagtaca caagatcagg tgtgccattt cggtaaagga tttccattcg ctcgatatct
      301 tcgtatttca atgcgcgatt aaacatgccc atttccagtc cgcctaggtt gatatcatgt
      361 gtcgcaactg cgtccccttc atggaagatt tcgattttaa atccagcaca cggatggatt
      421 tcaacaaatt cactgccatt gattcgtcca aaacttgttg tgatttgttt gatccaaaga
      481 tcgccgatat gacggcggtt gatcgtccag gtttctccat ttctaaaata aaattttagc
      541 gctgtcattt ctttactcat taaaaagact cctttatgat gtaatttatt cttgtactac
      601 ctcagtttag cacaaattta tgtaagtggt cacatcttat gttttttctt ctaatgacgt
      661 atctgcccac tttaagtagc caacaaagct gagcagatac agtctagtgt tttttaaatc
      721 aatttttctt tcgataaaaa atccaaaacc tgttttttat cattttttat tctttgttct
      781 acgacggctt tttcagctaa ttgcaaagct tcactaaccc acttaccagg tttttttcca
      841 gtttcttcta gcaagatttt accatctact gctaattcgc ttaatgactt gataggtaaa
      901 cgatcatagg attctcctac ggcatccatc tgaggtgttt cgtcaaaata gatcatcaat
      961 tcttctactt gcagtgcatg ttttttgcct aagaagtaca attcgaatgg ttccaaagct
     1021 ccagtttctc gttgtcgtag tccttggaca agtgcttgaa cgtctttaat catttggtta
     1081 gaacacttcc acgatttcaa aaaggaacga atctcatttt cttttagatc cagttggctg
     1141 atcaataatg cccatgcttg gctctcttct ttcaatggga cggatggtaa ttcagcaaaa
     1201 cgtaaaagtg cttcgccttc ttctttcaaa ccgggacagc aaatgtagca ctctgtttca
     1261 ataaatgcat ggattcccgc ggccccttca tttcccaaga gcatcttgat gaattccaca
     1321 tttatacgtt ctacagatat tttacctaat agctcgtggt tttctttgat ggcgtagaag
     1381 gtttcttcct ctaatttgaa ccctagttga ctgacaaaac gcaacccgcg catcattcgt
     1441 aaggcatctt catggaaccg ctcatgagga ttgcctacag ctcgcaagat ctgttcttct
     1501 agatcttgca gaccatcgaa caaatcgatg atttctccat cttctttcaa agcaaacgca
     1561 ttgatcgtaa aatctcttct tttcaaatct tctgccaacg aacgaacgaa ttcgacatga
     1621 tctggtctac ggtagtcctg ataagttgat tccgtccgaa atgtggtgat ctcatattgt
     1681 tcatcatttt ctaataccaa cacagttcca tgttcgatcc caatatctat cgtttttgga
     1741 aaaagctgtt tgatttcttc tggaaatgcg cttgttgcga tatccacatc atggattggc
     1801 tggttcagca agatatcacg aacacttcca cctacaaaat aagcttcata tcctgcattc
     1861 tctaattttt tcagaactgg aattgccttt tggtattcca gaggtaattg ttttaatttc
     1921 atttttccaa cctttcctgc gtgtttcttg tcctgagata aagactcagt tgcatggtga
     1981 ctgtttgaca agtccgtttc agagtcttca aggccaggac cacttcatct tgtttactcg
     2041 tccttacgct caaagcgatt atggtctctt tgattgaatt tttccatgtt tttttcaaaa
     2101 acttcagtta agtcgatatt caatgaatta gccatgatca tcgtaacgaa taaaacatca
     2161 ccaagttctt ctgctaccga gttaactggt tcagaagcct ttttgctttt ttctccataa
     2221 gtgtggttga cttctcttgc caattcacct acttcttcag ttaatcgagc catctgagct
     2281 aatggagaga aataccccac cttgaattgc tggatatatt catccacttc ctgctgcata
     2341 ctgtataaag aacgcttttt atccatcttt ttccctccaa aactatctta ccaaaacttt
     2401 aacgcaaatc ctagataaga gcaattgaga aaatcgaatt tccatgctac atttaggaag
     2461 gaatttctaa atggaaattc tgtgaaaata cataattgaa agctggaatt catatggtca
     2521 aacgaaaaac agtaaaagaa gttcttttta tcattatagg aacaagtatt tatgcatttg
     2581 gtcttgttta cttgaacatc gctaatcatt tagcagaagg gggagtctca gggatcacct
     2641 tgatcttaag agctttattt ggtattgatc cagcttatac gactttatta atcaacatcc
     2701 cattgatttt actaggagga aagatcctcg gtaaacgttc cttggcctat actgttctag
     2761 gtacactttc tttgtcattc tttttatgga tctggcaaag ggttccacta gaaatcaatt
     2821 tacagcatga tctactgatc gtttctctac ttgcgggttt agttgcaggt gtaggaagcg
     2881 ggatcgtcta ccgcatgggt ggaacaacag gcggcagtga tattatcgct cggattttag
     2941 aacaaaatta cggcatcact atggggcgtt ccctattggc atttgatatc atcgtcttac
     3001 ttgcttcatt aacctatatc gacttgaaac gtatgatgta tacgttgatt gtttcgtatg
     3061 ttttcagtcg tgtgattgat tcgatcttag atggcggata ttctgcaaaa ggtctacttg
     3121 tcgtctccaa caaaagcgaa gagattgcac cactactgat gaccggtctg caaagaggtg
     3181 tgactttcct ttctggagaa ggcgcattct ctggtaattc aaaaaaaatc atctatatgg
     3241 tcgttagctc tggtgaatta actgaagcta agaggatcgt ccacgagatt gacgaaaaag
     3301 ctttcctttc aatcatcaat gtgcatgaag tggaagggca aggctttact tatttgaagc
     3361 cacagacaag attactgaaa aaactataag aaaaaagaca aagataggct atgaggaaag
     3421 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
     3481 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
     3541 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
     3601 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
     3661 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
     3721 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
     3781 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
     3841 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
     3901 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
     3961 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
     4021 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
     4081 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
     4141 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
     4201 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
     4261 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
     4321 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
     4381 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     4441 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     4501 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     4561 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     4621 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     4681 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     4741 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     4801 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     4861 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     4921 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     4981 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     5041 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     5101 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     5161 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     5221 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     5281 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     5341 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     5401 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     5461 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     5521 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     5581 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     5641 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     5701 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     5761 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     5821 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     5881 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     5941 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     6001 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     6061 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     6121 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     6181 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     6241 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     6301 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     6361 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     6421 agataagagc aaagctcacc tcataacttg gaaataaata aaaattaaat aaaatacatg
     6481 tgttttctat gtatgacata cggattcgga atctctgtct cttatttatt ccttttctgc
     6541 taggaaataa aaagaaaagc acttgtagcc ctagagccac aagcgctttt tcaactgtct
     6601 tatttaacag cgtcttttaa tgctttacct ggtttgaatg caggtacttt gctagctgga
     6661 atttcgattt cttcaccagt ttgtgggtta cgacctttgc gagctgcgcg ttcgcgaact
     6721 tcaaagttac caaaaccgat taattgaact ttttcgccgt tagctaaagc atcttgaata
     6781 gttgaaaata cagcatctac tgctgcagtt gcatcttttt tagttaaatc agtagctgaa
     6841 gcaacttttt cgattaattc tgctttgttt gccatggata gattcacctc ctccacaaga
     6901 gatatgatag aaatatcatt tagttaaaac tttctgagtg gtccagaagt ttaaaaagaa
     6961 atattgatta acttcaatat tctgttatca cgatatcata tgaaccgctt aatagcaagg
     7021 tttttaccaa ttttcacatg ctttttttag tcatagaaac gtaacaaacg aaactgtctt
     7081 tttcttttga aaaaaaaacg tcgatatggt aaaatgccta ttttctccta cgagggataa
     7141 ttcggatgga cgtcccttca aaagtaaatg cttttctgat ttgattttct aagaaacgtt
     7201 cataagaaaa atgcatcaat tcctcttcat tgacaaaaac gacaaatgta ggtggtttga
     7261 cagcgacttg tgtagcataa aaaatcttca ggcgttttcc tttatctgtt ggtgttggat
     7321 tgattgctac agcatccata atgatatcat tcaacacagc cgaagagata cgaagattct
     7381 ggttcatact tacttgttcg atcatttcag gcagacgttc caaccgttgt ttagtcactg
     7441 cagaaacaaa aacgattgga gcgtaatcaa gataccggaa ttcatcacga atctcttgtt
     7501 cgaaatcacg cattgtattg gtttctttct ttacaagatc ccatttattc acgacgataa
     7561 taattccacg accagcttca tgggcgtaac ccgctactcg cttgtcttgt tcccgaatcc
     7621 cttcttcagc attcagtacc atcaaaacga tatcagaacg gtcaatggca cgcattgcac
     7681 gcatcacgct gtatttttca gtattttcgt atacttttcc gcgtttacgc ataccagctg
     7741 tatctatcat taagaatttc tgaccacttt cagaaacgaa gtgggtgtcg attgcgtctc
     7801 gggtcgttcc ttcaatatcc gaaacaatta cacgttcttc tcctaaaatc gcattgatca
     7861 aagaggattt accaacattt gggcgaccaa tcaaactaaa cttaatcgtg tcgtcgtcct
     7921 cttcttcagt ctcttcagag aaatacttca ctgcttcatc taaaatatca ccaatcccta
     7981 gtccatggct tcctgaaaca ggataaggat cgcctagccc taaggaataa aattcataga
     8041 tatcgtttct catttctgga ttatctactt tattgactgc taaaatcact ggtttattac
     8101 ttctgtataa aattttcgca accatctcat ctgcgtctgt cacgccttcg cgtccgctga
     8161 ctacacaaat gattacatct gcttcttcaa tcgcgatttc tgcttgatgc ttgatctgat
     8221 ccataaaagg ttcatcgcca agatcaattc cgcctgtgtc gatcacgctg aattctcgac
     8281 ctaaccattc accttttgca taaatacgat cacgagttac tccaggagta tcttcgacaa
     8341 tcgagatacg ctcaccagcg atgcggttaa aaatcgtaga cttaccgacg ttcgggcggc
     8401 caacgattgc aattgttgga tttgccatat tatttcctcc tcacaagttt ccaatctcac
     8461 ttagtttaac gaatgcattg ccaactttca agcatagatt gtcaattaaa cgaagtattt
     8521 ttattcctta ttgaaatact aatcgctttt caaaagaaaa actgagacaa aagcagctgc
     8581 tttcatctca gtcacagata caaaatcaat tatttttcag aatcatcggt tgctttttct
     8641 tctacttctt ctttcaacgc atcacctaaa atgtctccca tagtaaatcc agtattttct
     8701 tctggtaatt cataagactc aacatttttt ggttcttctt ctgaagctgg tttttcttct
     8761 aaagctttga tactcaatgc aatacgatgt tcttctggat ggatctctaa tactttcact
     8821 ttcacttcgt caccttcatg aagcacttca tgtggtgtcg caatatgttt atgtgaaatt
     8881 tgagagatat ggactagccc ttctactcca gggaacactt caacaaaggc accgaagctt
     8941 gtcaaacgtt taactgttcc gtctaatact gtgccaactg gagcttttgt atcgatttct
     9001 gaccaaggtc caggctgtgt gtctttgatt gacaaggaaa cacgttcttg ttcaggattg
     9061 atagacaaca ctttgacatt tacatcatca ttgacagcca atacatcact tggttttgct
     9121 acatgactat gtgaaatctc tgagacatgg actagaccgt caattccgcc taggtcgaca
     9181 aatgcgccaa aatcagtaag acgtgcaaca cgtccactga gaacatctcc ctcatggata
     9241 gttgaaagaa tttctttttt cttttcttct ctttcgtttt ccactaccgc tttatgcgat
     9301 aagatcaaac gattttctga tggttcgatt tcgatgattt taaagctcaa tgttttgcct
     9361 ttatagtctg aaaagtctgc aacaaaatga tcttccacca ttgatgcagg gacaaaacca
     9421 cgtacaccga cgtcaacgac taaaccgcct ttgacaacat ttgtaacagg tgcttcgatg
     9481 accttgccct cttggaaatc tctttcgata tcttcccaaa cttttttagc atctaaacgg
     9541 cgttttgaaa gtaggtagct gccgttttct ttatctttgc cgatcgtact gataacgact
     9601 aaatctaata catcaccgac ttttactact tcgctgatat cttctaccgg caaagttgat
     9661 aattcttttg ccggaacgac tccttcaact ccagcccctt cgattccgac aatcacttgt
     9721 ttgtcttcaa tgactaaaac ttcgccctta acaacatcgc caacttttac ttcttgtacg
     9781 cttttcattg cgtcttccat tgactggttg ttctcttgat tttgatcaaa ttctgtcata
     9841 acacttgtcc tcctaaccaa cattctgccg taagtacggt actgttttta gtttaattga
     9901 ttattcaaaa aaaataaagc gatttcgttc gttttccttg aaaaaacaat tgtttttcat
     9961 tttttttctt aatttaaaaa agaagataac cttttttcaa aacaacagct tttattgctg
    10021 caacgacttc tggaatcgat ttgccagtcg tatcgatacg aacagcatcc tctgcttgct
    10081 tcagcggaga gacgtccctt gttgaatcat aatggtctct ttcctgtatc tctttcgtca
    10141 gtgtttcaag atcagtcgga attccttttt cttggttctc tttgaaacgt ctttctgcac
    10201 gctcacttac gcttgctact aaaaagattt tcacttctgc attcggtaat acagctgtcc
    10261 cgatgtctct tccgtccatg acaacgccac cgcgttcccc tatttttcgt tggacagcaa
    10321 ctaattcttc tctgactttt ccatgtgcag agacttcaga aacagctttt gtgacatctg
    10381 gttgacggat ttctaaagtc acatcttttg atgctatgaa tacatgctgt ccatcttctt
    10441 gttgcgaaaa agagatagga tactttttga tcagcgaaac tagcccttct tcatctgaaa
    10501 aagatacatt gttcgtaata gctaaataag ttactgcgcg atacatggca ccggtatctg
    10561 tataaatata attcaattct tttgctaata tcttggcaac ggtacttttc ccagatgaag
    10621 caggcccgtc gattgcaata ctgatttgtg tcatgatata actccttttt ctcagaaaaa
    10681 aagccgcaaa gcgcggctat tattatttaa ttcttaattc ttgaccaggg taaagcataa
    10741 agttgtttgg atctaagcca ttcaattcaa acaattgatc agtggtgatc cctgcacgct
    10801 cagccacttg ttttggacct tcgcctgctt gaacagtcgt tgttgaaccg gctgcagctg
    10861 atgaagaagg tgttgtttct gctgcattgc tgcttgaatc ccctgcttga taagttgcct
    10921 cacttgagga agtcggtgtt gtctctgctg caatactgct ttctgacgtt acacctgtat
    10981 cttgagacac agtagattct tccgcgattg tactagattc tactgttgaa gtctcagttg
    11041 actcctcttt tgttgtactt gtagaacttt ctactactga tgtcgaagtt tcagaagaag
    11101 ttgctgctgt tgcattgttg cttgatccat ttctgatcca gaaataagca cctgctggaa
    11161 tagcgataca taagaccagt aaaatcaaaa atagcgaaag aaataatgta tttcctttct
    11221 tttgttgtct ctgagaactt cttgatgaaa cttcatcatc tgtatcgtag attggttgtt
    11281 cccatggttc ttgtgtttcg ttattttctg tagattgatg tctatctttt ctgctcactg
    11341 ttttacctcc taaactctat cgtgtgtatt ataccatagg aaaaagtgtc ttgtcctaaa
    11401 aaatcaatgt tccatgtttt ttttaaataa atttagtaaa atcgtttccc aatgaagttg
    11461 ttcagtctta gaaaaaagct tcctctttgg cagaagttct gcttttgctc catcaatatc
    11521 acaacaattc tgcggctttt cggagagttt ttcgccaaaa taagctaaga tgaattttct
    11581 gcggcagttt tcttcattaa tatagcgaag catctgctgc aggcggaatt ctttttcttt
    11641 ttcctgacgt ttgagccgtt ccacccaatt ttctggtttt tcagactgct ggatcagctc
    11701 catccatttt ttttgcagct catcaaaggg agcttgcttt gtggcatatt ccaaataaag
    11761 ctcaaaactt tgtcgctgtt ctctagaaag ttgattaaag aaataatgga tacgttcatc
    11821 cccactttga taaaaaagaa ttgctgcact ttcttcctga tctctgcctg ctcgaccgat
    11881 ttcttgtaca tagttttcta gactgtctgg caaatcataa tggaccacat aacggatatc
    11941 agatttatcg atccccatac caaatgcatt cgtagcaatg agaaactgca gctgattttt
    12001 tacaaactgc tgttgaagtt gtcttctttg agctgcatca agaccaccgt gatagtatcc
    12061 aactgtaaaa cgttccctga ataaatgata caatcgttcg acttcttttt ttgttgcaca
    12121 ataaatgatt gccgctcctt gtgctctttc catgaagtgt tcaagttctt gttctttttg
    12181 ctgcgttttc cgaacaaaaa gcgagatatt ttgccgattg actgattgtc tgatctcttt
    12241 tggtggtcga tcaaatagta catgacgtat atctcttgct actaaatctg ttgctgtcgc
    12301 cgttagtgcc agtgtgaccg ggtttcctaa aagctttcgg atttttccta actgttgata
    12361 ttctggacgg aaatcaactc cccattgaga cacgcaatga gcctcatcta ctacatataa
    12421 cgcaatattt tgttttttca gatgctctaa aagagaagga ttagtcaaca tttcgggact
    12481 caaaaacaaa aatttatatt gcgatagatg acggaggacg tatcttcttt cagattgcga
    12541 aagtaaacta ttgaaagcag ctactcgttt ctcccctcgt ttttgtaatt gcgtcacttg
    12601 atcttccatt agagaaagca gcggtgacac gatgatgacc agaccttcca ttaaataccc
    12661 cgtcaattga tagcaaaggc tttttcccgt tcctgtaggc aaaatagcga gagtatcttc
    12721 tccatcaagc aacgcctgaa taatttcttc ttggccggga cgaaatgaat caaatccaaa
    12781 atattttttt aattcattta ttaacattct gtatcgcttc ctttctcaat agatagattt
    12841 gatacaaacg aaattctcca taatctaatt gtccatctac attccattcg ctaaagcgcc
    12901 actctcgcac ggaatcctta tttggttcca aacgttcgat tgtttctgca gagagaatcc
    12961 actcgtatgg aaaatcatca aaaaacaagg cccactcaat aagatgatct gttactgttc
    13021 ctctttttaa atgacggatt gccatgatct ggtcaattgt ctgaccattc ataaacatct
    13081 gcttggtgat catcatgctt tgattgaaat tttgctgtaa taatgaatcg atcaaagcgt
    13141 gccaaagcga atctggccgt ttttcgattt gtgctaacaa aaggtggata catctgcttt
    13201 gttgcagata aacctctgac tcatcattgt tttttgccag ctgataagga agcagccctg
    13261 ttcgctcatt tccagataat tggttagcta aaaaatctgc tgcttcttct ggtatctccg
    13321 aaaacagctg caccaaactc tcatacgcag tatcaatcaa aatttcacgt ggcaattggc
    13381 tttcactaag ccattttttt agttggaaag tataaaaagg acttgtctct gctggaagat
    13441 agtcttgaat acccgttgcc agattagaaa ttacttgaac agcaaattta atgagccgcc
    13501 aactagtttc ccctgttctg ccatagcggt caaaacgcaa accagtatgt tctatttgat
    13561 gttcggacaa catatcagcc cctgcaggcg ttagctttgc ttcattttca tttatttcga
    13621 tccaaccttg ctgcgcaatt ttttgcaaaa tttgataaaa cttatcctgc ttcaattctg
    13681 gaaaactgtt atggataaac aaaagttcgt gggtaaatcc ataaataagt actgaagtcg
    13741 ttcgttttcc cacaaggagt tggtaaagag aactaatccg cagcttgtgt cctgatgaaa
    13801 atagcgataa aataaaaaca atcatattat tctccttaag ttaggatggt tagaaatgtc
    13861 actactatgt aaacttgtac ctgaacgctg tattgcatgc ggtctttgtc aaatcgaagc
    13921 gccagatatt ttcgattatg atgaagaagg aatcgtttta tttgcccaag aaccagaggc
    13981 tcatcaacag ttcgtgatgc cggaagaaga aacatatgta aaaaaagcgt atcaaaaatg
    14041 tccagttcga gcgattttat tagaaaataa aatataaata taaacgaaac tttaaaaacg
    14101 tacactaagt tctctaaact tgaaaataag ccgggatctg tttctcttgt tccgtgaaat
    14161 cccgacttat tttgaaagat tcatttgcta tctatagtta attgactagt tttttcacgg
    14221 accctatagg acccatttat attatttcaa ctttttcagc cagttttcca atgtattgac
    14281 gatcacagtt tgctggtctg cgttagaaat ttctgcctct ccatctcctt tttgctcacc
    14341 atagctgcca aaacctccat gatttccgcc attgattgat acatactctg ttctttccgg
    14401 taaatactgc ttagcttctt gataagcttc ctgattcaat actttatctt ttgtcgccgt
    14461 gatcgataaa acaggaacag ctgattctgt caatgttcct tttttgtcgg gataacttgc
    14521 catgaagaat acccctttta aatgtttgtc tgaatgattc ttattgacat aacgacttgc
    14581 cattacgcca cctaatgaat ggccaccgat cacataatcg gaatttggaa aatcttcttt
    14641 gaccttatcc gctttgtttc cgcccatcac tgctagatca agtggcattt tgacaatagc
    14701 gactgaaaag ccgttttttg ctaaatcttg cgcccaaata ctataacttt ctggctctac
    14761 gagagcacca ggataaaaaa taagtaatgg agactttcca tgattctttt tctctccttc
    14821 aaaaaataag taatcttctt tgttttttcc ttcttttacc aacacttgcg cttctgacga
    14881 tggttcgtac gtattttgct gtatatagta ataaccggct ccaccgagta atcctaaaat
    14941 gatgactaag ccaattagta ttcgtctaaa tattttcact ttctcccacc ttttctatct
    15001 gagtgacccc tttttcttaa tcaagtatga ttatacctta aaaaaataag agagaaatgc
    15061 aaactttcca gcatcaaata aaaaaagacg gaatatccat ttgaatatcc gccctttttg
    15121 tatgtttatt tttatttagc acataaacga tacacagctt ctgcataaat ttccattgct
    15181 ttatacatac tacttaattc ccatcgttca ttcgcctggt gcataaagtc aggagtatca
    15241 gggaacatcg caccgaatgc cacacactgg ttcatcgtac gagcaaaagt agcgccgcct
    15301 gatacaaacg gttcagtcat gtctccagta atatcgcgat atgtccccaa tagatttttc
    15361 actaactcac tgtctagtgg cacgtataat gaatcaagga agtcaaattc ttcataagtc
    15421 aacccatatt tttctgctgt tttagttaat ttagctacta aatcatcttt cttgaatgta
    15481 acagggattc tcatatctac accgattttt gtttgttctg gtgtgatttc caaacttgca
    15541 aagttcatcg ttagctcgcc ggattgttca tcttctgttt tgcccacgac agcttcacca
    15601 gttgcatttt cttgaactaa ttttcctaag aaattgattg ggccaaaatc aaatacttct
    15661 gaaagagcaa ttgccagacg agaaatagca ttcactcctt gtgctgcatc tttcgcgtgg
    15721 atacttttac caagaacgac gatgccttca ccttgttctt cgaaatcgaa ttcgtgtttt
    15781 ttcaatgctt cttttacttc agaaagcttt tctccagagt aaggagctgc atcaggaaca
    15841 acattcaacg ctcctccagc ttttacagaa aactcgttcg ttcctggtcc tgtcaagtaa
    15901 gcttgcaata agcctttttc tgcataaatt aaaggaaatt cagcatctgg cgcaaatcct
    15961 tgcgtaattc cttcttcttt ttcgttatat ttttctaaac aacgccataa attttcttca
    16021 tctgtaccaa agataaaacg aatacgtgtc ttgaattcca cgccagcatc aatcaaagct
    16081 ttgacggcat acattgccgc aatagaagga cctttgtcat cttgggatcc gcgaccaact
    16141 aaccagccgt cttttatagt tggatcgaat ggttttgttt cccaattatt ttcgtcccct
    16201 gctggaacaa cgtccatatg acacaagata ccgaataatt catctccaga gccaatctct
    16261 gaataaccgt aatagccttc tggatcttta aatgttctaa atcctagctt ttcactgatt
    16321 tccaatactt tatccaaagc ttcaatcact tttttaccga agggatgtcc ttgtcctgaa
    16381 tctgcttcat ctagtacgga aggaattcgg atcaattcgc tcaatgattc taatgcttgt
    16441 tcatgatgtt gttctgtcac aaattttttc atgatattat cctcctaata tgttaaaaag
    16501 ggtcatgtca aattcctccg acacaacctc ttcttctcaa ataatgacgt tttaagcctg
    16561 ctccatcagc aagcagaatg ttcttaacaa atgatgaaag aaaaaacact cactgaatgg
    16621 agctattgac ttgtccacgt gcttatcgat agccgtttat cggtttcttc attcttatga
    16681 tagaccttgt acctgtattt gtctaggttt agaacattgc tgctacacct aggatcacac
    16741 agatggctac aaataatatc gcaattaatt taccggtaaa tttccaccac actgaaacat
    16801 cgaaacgagc aattgctaca gcacccatta cgatagcaga tgttggtgta attaagttta
    16861 ctaaaccaga tgcagattga taagcagtga ttactaaatc cttaccgacg ccggcaaatt
    16921 cacccatagg tcccatgatt cccattgttg cagcagctaa gccggaagtt gaaggaatca
    16981 agaatgacat agggatatag aaaataaatg taataatgat gaatacactt gaagataatg
    17041 aacttaatcc ttgttcgccc caatgtaaga tggtgtctgt gattaatcca ttgttcataa
    17101 ccacttggat accacgagca acagctacta cgattgctac accgatcaaa tcagaagcac
    17161 cagctaaaaa ttcagagaca aattcagact ctttcatgcc ataagtgatt gctactacga
    17221 tggacattac taagaataac atagtaattt ctgggaagta ccagtcacct aatggaagca
    17281 tgcttttacc tagaaccgta cctagtaccg gaaggtttgt taaccagttt gtcaatgatt
    17341 caaaaatcgt gaaattcgca ttcaaggttg tccaaggaat caaactgatg atcatgatac
    17401 caaaagtaat aaagaacaat acattaacat gtttttgttt tttcgtgatt acttcttgac
    17461 gaccgattgc ttcaatatcg aaatgcttca tatcttcttt acgttggttg tatactaatg
    17521 attttgttgg atctttttcg atctttgatg cataacgata cacatataca atagaaatag
    17581 ctaacaaaat aacgaacatc aagaatcgaa gaccaatacc ttcacccatc gaaatcccaa
    17641 cagcttgtga agctacgcct gttgcaaaag gatttaccgt tgaagctaga cagcctactt
    17701 gagaccctac taatacgatt gctacagcta ctactgtatc aaagcctaca gccatcatga
    17761 ctgggatcag taaagcatag aatggaatcg tttcttctgc cattccgtaa gtagagccgc
    17821 ctaatgcaaa taacagcatc aatactggaa taagcatttt ttcttttcct ttgaatttct
    17881 tcacaactga agcaatcccg gcatctagtg cccctgtttt gttgataata cctaaaaatc
    17941 caccaacaac caaaatgaag aaagagattg ggattgcagc aggtgtttct ttagttagct
    18001 cccccgctgg tacacctagc atcccattga ttggcgccat gaaaatatcc cacagccctt
    18061 gaggattttg ttgtactcgt tcatatgatc cagcgacgat gttgcctgca tcgtctacac
    18121 tatagtgccc agctggtata aaccaagtaa gtacagcgat tactgcaata ataataaata
    18181 agaccgtata cgctgaaggc atttgaaatt ttttcttttt tgtttgttcc atcttcttct
    18241 tcctttcttt tccgttagag acaacaattt tggctctaat gttattttat caaaaagagt
    18301 atcagaacaa aaataataac acgcattttg taaaactttt gttcaaaaag ttcgtttttc
    18361 cctattccct cctctttttt cagtttttta aagctttctt ctttttcatt gtagcgtttc
    18421 ctttttttta taaacaaaca ttttcgtctt ttaaaaggag aagaatttca catttgcaaa
    18481 gaattgattg atttttatgc ataaatcaaa aaaatactca aaacaaacaa ataaaacgtt
    18541 tacattattg catgtcttgt atttttttcc aaaaaaaaag accaagaaat ttcttgatct
    18601 ttttgatatt tatttgactg ctgtatgacg ttgttcgaac tgatgttgtt ttcgacttaa
    18661 ccatggaaga agttgcgcat gcagcactaa aaagacagca ctcacgatga atcctttgat
    18721 caagttgaaa ggaacgatcc caatcagtac atagtttgct aaagacatgc ccagcatctg
    18781 tgttgcgttc agccctaaaa acattaagta aagaggcgta ataacgaaat aatttgcgat
    18841 actcataaaa atagttagag cgatggttcc tgtaatgaca cctaaaaatt tgtttcttcc
    18901 tttatgctgt ttctttacac taaagaaata ataaatcggg aatgtaaaga tcgttgttga
    18961 taagaaacta gcagtgtctc ctaccaaatt atccggagaa aaacctgtag tcagcagatg
    19021 taatactgaa cgcaagaacg ctgttgcaac tccggccgct ggaccgaata agaacatgct
    19081 gatcaatacc gagatatcac taaaatcgat cttcaaaaaa ctaaaagccg gcatgatcgg
    19141 aaaagcaaaa tactgtaaaa ctaatgcgat cgcagcaaac atcgctactg caaccatttt
    19201 ctgtacacgg gtgttcttca tttgaaatcc tcctgttagg actcctcttc agcgaacttt
    19261 ttgacgtttc tctccaaatg aaaaaactct attttccagg gaaaatagag ttagagttat
    19321 ttgatcaagc gtcgtcaaat aagctctatc ttctttatcc agactatact gtcggtatcg
    19381 gaatttcacc gattcagcta tttttttgca aaataggtcg tggactataa ccaccggtcg
    19441 ggaatttcac cctgcccctg aagacgaacc ttatataatt tttgtttaca tattcattat
    19501 acatatctat tcaaaaaacg caacatctaa caattataaa aagtaagtgt tcattttgag
    19561 tggttcagca aactgctgac ttcttttttg ttcagttcac ggtaatcccc aggacgtagg
    19621 ccttgtaaag tcagatctcc gtatttttca cgttttagtt tttgcacagg aagaccaact
    19681 gcttgaagca tatttttcac ttgatgatta cgtccttcgt ggatcgtcaa ttccacgata
    19741 ctgtggtttg tcttaggatc cactgataaa atttggaatt tagctggaga tgtttttcgt
    19801 ccttcgatct ttattccttt tgtcaaaggt gcaagcatcg attttgtagc gatccctttt
    19861 acctttgcaa cgtaaacttt atccacttca tgttttggat gtgtcaggcg ctgagcaaaa
    19921 tctccatcat ttgtcagtag caagatcccc gaagtatcgt aatccagtcg acctacagga
    19981 tagatacgtt cttttaccat cggcaaaaga tccgtaacaa cttttcttcc tttgtcatct
    20041 gcaacagcag aaataactcc tttaggtttg tacaataaat agtaaccgta ttcttcttga
    20101 taaattggga cttcatccac ttccacagtg tcatgtttcc caacttttat ccctaattcc
    20161 cttacaactt gtccgtttac ttttacacgt cctgcaagga tgaattcttc tgcttttcga
    20221 cgagaagtga tgccagcgtg ggcaattact ttctgcaatc tctccattac aattattctc
    20281 ctttattcat tccatcaaag aatagatctg gtgacacgtc ttcttcaagt gaaatttcca
    20341 tttcttgtgt atcaggcagt tcttctaatg atttcaaacc aaaataatct aagaagtagc
    20401 cagttgttcc atataatatc ggccgacctg gtccttctac tctacctttt tcttcaatca
    20461 gtttatgggc agctagacgc tgtaccgctc ctgaaacctg aactcctcga atctgctcga
    20521 tttcagctct tgtgattggc tgtttataag cgatgattgc taaggtttcg acggcggctt
    20581 gagataatgt gtttgatgtc ccttgcgcat atcgcttaag taagggagcc agctcttttt
    20641 tagtcgttaa tacataatgg ctttccgttt caaaaatatg caaagctgag tgcgagtttt
    20701 gagtgtaaga ttcttttaat tctttcacta aacttgtgac ttctgcttcg ctgagattta
    20761 acagtccgct taattcttca ttactgatcc cttcctcgcc aacaataaaa agaagggctt
    20821 caagttcact taatttcgtc atgttcggta tctcctactg ctggataaag cataattgat
    20881 tcatagtttt ctttttgttg cgcaatgatc tgcccttttt tcatcaattc tagcaaagcc
    20941 ataaaagtag tgacaacttc acttttagaa ggtgactcaa aaaaagaatc gaaagtacag
    21001 ccatgcgcat ttctttttat acgctcttcg ataaatacca ttcgttcttc gatcgttgtg
    21061 tcatcgggcg tgatcgtttt ttccactttt tgagaaaatt tcttacgttc taagattttc
    21121 tgcatggcac ggatcaaatc gatttttttg acttgtcctc gcttcaacgg cttttcagca
    21181 tccgctaacc catcgatgtt cataggttct tttgtgtaat aaagacttcg ttcctctgct
    21241 ttttctgtca gtctttcagc tgcatattta tatttacggt attctaaaag ctgagtgacc
    21301 aattcttctc gaggatcttc ttcccataat tcttcatcgt ctgtgccgaa ttcttggaca
    21361 ggaagcaatg tcttgctttt gattgccatc aatgtagcag ccatcactaa gtattctcct
    21421 gcaacagcta gctcgagtgt tttcattgta tggatataat tcatatattg ctccgtgatc
    21481 gtagcgatcg gtatatcata tatatcgatt tccatttgct gaatcagatg aagcagcaga
    21541 tcgagaggac cctcgaatac atctaattta atattgatct ccgtcaactc attcactctt
    21601 tcttcttttt ctttgctagc cattttccaa tgtaaggctc tgtgatttca gttgcacgga
    21661 tggagacatc cgggtacttt tcctgtaatt catctaacat ttgaaagccc atattctcac
    21721 cgcgataaga cggattcaaa gaaatgtcat ggatgatcag ctgatcgttc gttgcccagt
    21781 aaataccaat aatcccttga atgttggttg aaccttctgg cgtaaagaaa aaaagttcat
    21841 aatcgtcttc agattcgtac gtatcaatct ccttcaacaa agaagtttta cctgtcagtt
    21901 tcttatggaa actcaatagt cccatagcaa ttttacggtt ttctttccgg taatgtgtta
    21961 acatcttctc accttcctat gactaagccc ttggaaaatg ctgcttataa acatccgtca
    22021 ttcttttctt cgtgatatgt gtataaatct gagtcgtaga gatatccgcg tgacctaaca
    22081 attcctgtac tgtccgcaaa tcagctccat tttctagcag atgtgtggca aagctatgcc
    22141 gcagcgtatg tggtgttact tctttgtaaa tcccagcctc tcgtactaac tgcttcagat
    22201 ttttccagat tccttgccga gaaagacctt tcccatgatt attgacaaat acatgcattt
    22261 cagatgcgtc ctttacaagt aatggacgtg cttcgtctaa gtagcgttcc agccattgga
    22321 tcgcataatc acctaaagga atgatccgct ctttatctcc ttttccaact gtctgtacca
    22381 gtccaagaga aagatgaaga tctcccaatt tcaatccaat caattcactg acgcgcatcc
    22441 cagtagcata catgacttcc aagattgcac gatctcttat ccctaacgtt tttgtcgtat
    22501 caggtgcttc aatcagcttt tctacttctg tcagagtcaa tgtacttggt aatttctgtg
    22561 ctttcttcgg cgtatcgata tgttgcatcg gatcatgatc agtgatacgc tcttgccgta
    22621 aaaactgatg gaatcttctg agacttgaga tcatccgagt aacagttgct gtcgcttttt
    22681 tttcttcatg caacttctcc agaaaacgga tgactaaaaa gcgatcgaca tcctgccatg
    22741 aagcaatttt ctgctcctgt agaaaatgca agtactgttc caaatcacgt tcatagcttt
    22801 gtcgtgtatt ggcggacaat ccccgttcaa tattcaagta gtggagataa tcgttgattt
    22861 gctctttcat aataatcccc ctcatgcctc tctatcatat cagataccgc ttcattctga
    22921 tagtcttttt ccataatctg agcaaagaaa aagccgtcta gacactcaga cggactggtt
    22981 tcttttttcg gctctataat ttatgggact gatgaatcag aattgattct tcagccccat
    23041 tttcatttta ggtattaaaa a
//
LOCUS       DACGDM010000034        22502 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.034, whole genome shotgun sequence.
ACCESSION   DACGDM010000034 DACGDM010000000
VERSION     DACGDM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.034"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..466
                     /locus_tag="IXR05_001457"
     CDS             <1..466
                     /locus_tag="IXR05_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4259969.1"
                     /translation="DTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNG
                     LPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(537..1847)
                     /locus_tag="IXR05_001458"
     CDS             complement(537..1847)
                     /locus_tag="IXR05_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4259970.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1859..3277)
                     /locus_tag="IXR05_001459"
     CDS             complement(1859..3277)
                     /locus_tag="IXR05_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4259971.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3517..5085)
                     /locus_tag="IXR05_001460"
     CDS             complement(3517..5085)
                     /locus_tag="IXR05_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAQ4259972.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5089..5370)
                     /locus_tag="IXR05_001461"
     CDS             complement(5089..5370)
                     /locus_tag="IXR05_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAQ4259973.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(5367..6290)
                     /locus_tag="IXR05_001462"
     CDS             complement(5367..6290)
                     /locus_tag="IXR05_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAQ4259974.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6287..7165)
                     /locus_tag="IXR05_001463"
     CDS             complement(6287..7165)
                     /locus_tag="IXR05_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4259975.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7152..8489)
                     /locus_tag="IXR05_001464"
     CDS             complement(7152..8489)
                     /locus_tag="IXR05_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4259976.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8492..9595)
                     /locus_tag="IXR05_001465"
     CDS             complement(8492..9595)
                     /locus_tag="IXR05_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4259977.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9669..11177)
                     /locus_tag="IXR05_001466"
     CDS             complement(9669..11177)
                     /locus_tag="IXR05_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4259978.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11143..11835)
                     /locus_tag="IXR05_001467"
     CDS             complement(11143..11835)
                     /locus_tag="IXR05_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4259979.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11857..12831)
                     /locus_tag="IXR05_001468"
     CDS             complement(11857..12831)
                     /locus_tag="IXR05_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4259980.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13131..14003
                     /locus_tag="IXR05_001469"
     CDS             13131..14003
                     /locus_tag="IXR05_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4259981.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14585..16783)
                     /locus_tag="IXR05_001470"
     CDS             complement(14585..16783)
                     /locus_tag="IXR05_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4259982.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            17015..18007
                     /locus_tag="IXR05_001471"
     CDS             17015..18007
                     /locus_tag="IXR05_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4259983.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            18067..19488
                     /locus_tag="IXR05_001472"
     CDS             18067..19488
                     /locus_tag="IXR05_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAQ4259984.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19481..20980
                     /locus_tag="IXR05_001473"
     CDS             19481..20980
                     /locus_tag="IXR05_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAQ4259985.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            21019..22413
                     /gene="uxaC"
                     /locus_tag="IXR05_001474"
     CDS             21019..22413
                     /gene="uxaC"
                     /locus_tag="IXR05_001474"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4259986.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6831 a         4584 c         3898 g         7189 t
ORIGIN      
        1 tgatacgatc gttggcattc atcataaaag tgccgtcatt actttagttg aaagattatc
       61 taaagtcatt atcacgatta aacccaacgg ccgtaaggca ttagatattg aaactgccct
      121 taatcaatgg ttttctcgct tccctaaaaa cttctttaaa tctattacgt ttgactgtgg
      181 aaaagaattt tctaactgga aagccattag taaccaacat gatattgata tatattttgc
      241 ggaccctgga acaccttctc aacgcccatt aaacgagaat tctaacggga ttctgcgtcg
      301 taatggactg ccgaaatcaa tggattttag aaaagtgaat cagacattta tttccagtgt
      361 cagcaatcaa cgtaatcata ttccaagaaa atcattgaat tacagaacac caatcgaaat
      421 atttttgagc tatgtacaag aagcatttta ttctagctta atttgacaaa tcatatatca
      481 ttaaaaaaaa taaaggtcaa gctaaaatat tatttaagct tgaccttatt ataatttcaa
      541 cgattgtcaa aagtattgtt tgcagctgtg ttgccagttt ctatagataa atcacagctt
      601 ttgaaacata agttttgtac tgcttcgatt cgcccgaatt cttttgcagt tatttggcaa
      661 tgagaaaagc agacatcttc tataggcttt tcaggaaatg ctactaaatc aaaagctcgg
      721 gaaggaagtg agtaacctgg agaaaggcat gcctgtacgt ttttgatgtg tatgtctttg
      781 actttcgtca tttgctttga ttcaggtatt tcttcagcca ctgcttgcca actttctggc
      841 atttgagcaa ggtcattgct attttttcta ttgtattcat tatgccagtc cattatccaa
      901 gaaaaaggaa attgtacatc aatcatattc agattttcta ccctgatatt ttcgatcact
      961 ccccctcttt cttttgaaga tttcattcga ataccacagt ctgactgaaa aaaattgata
     1021 tcgtgaatat atacgtcact aactccagca ctaacttcgc taccaatagt tacaccgtat
     1081 cctgaacgga ttttacatct agcaacctcg attcttgatg attttcgatt gactcttgca
     1141 ccattgccat ctctgccaga cttaatagca atacaatcat caccacaggc caaatcacat
     1201 tcatagacac gcacatttgt tgaagaatca atatcaatcc catctgtact tggtccatca
     1261 ttgttgcgga tgattacttt ttctactaat acatcgttag aataagtgat ttgcaagttc
     1321 caaaaacctg atttctgaaa aatcaaatca cgaacaacaa catgttctgc atgatacagt
     1381 aaacaagcgc gtggacgttt aatagcataa tccgcaatcc aacgaagtcc cttttgatcg
     1441 tattcagctc ttgtcccgct tttttgatct tttccccaat acagctccca ccaatggtct
     1501 ccttgaccgt cgattattcc ttttccttct ataagaatat ctttcgccga gagaacattc
     1561 aaaatcgctg ctggccattt catttctacg ccggctactc gtgtatcgat ttctggaaat
     1621 gcttcgatat ctgttctccc cttgaggact gcaccttctt caaagataag atgactctta
     1681 tcttttaaaa aaagggctcc gactaaataa atgccttttg gaataaatac aggtaagtgt
     1741 tctttcgcac cttgatcgat tgctttttgc agtattattg tatcatcttg ttgagtgtcg
     1801 tttgttttaa agttcaaagc attgataatc cctttttttg tccgcaatac gtttctccct
     1861 atctttcatt gatttttttc aattcttcac caataaatac agtttttgaa cgattcagtg
     1921 ggtaacctac tagcaaaatg attgcggata caaataagca gaatgctggt aacaagtttg
     1981 ccatcgtata aatcctttct tgtactaaaa ctgattggat ggctccacct gttgtagacg
     2041 attggtaacc aatgagtgcc agcataaatc cgcctaccgc tcctgcacat gcttgtccta
     2101 cttttctcgc aaaagaattt actccatata ctgttccatc ttctcttaag cctgtcttat
     2161 attgatgata atcaatcacg tcagtaatga atgcccagac catcaaattg aataaaccag
     2221 atcctaaagt agcgataaat aaaagaatca gatataccca tgcatttgtt atatgaagga
     2281 aatacatcag caagtacata catgaagaag caagtaacgc aaatacgctt gcttcctttt
     2341 taccaaataa ttttgtcagc tttgtagcaa atggtgctaa aactactact gttccgtaag
     2401 taaataaaag agcaacagac attgcttgtt tattatggaa gtaatcattg aataaataag
     2461 tcatattcgt cccagctaaa atctgattga tcacaatgaa aatgtcaaca atgactaaaa
     2521 taatcagtgc tcgattagct aacaaacctt ttaccaactg agaagcagat actttttcgt
     2581 ttttgacaac tcttactctt tcagtagtca atttacaagt taacatatat gcgacaaatg
     2641 ctattgcagc acatccgatt gaaatccaaa agaaatgatt ccctgaaacg acttgttgtc
     2701 cactcttgtt atgggtatac attaaaatcg gaatgaagaa tcctgtagtt gatccgccaa
     2761 tcgcagaacc aatgcttcgg aacgtggaca acgaggtgcg gtcattagga tttgagctaa
     2821 ttgctgctgc cattgctcca tacgggatat tgattgttga gagaaaaatc ccataaacaa
     2881 tgtatgaaac aaaaatataa gcaatcttca ccgtcattgg aagatgttgg acgaatggca
     2941 aaaacaaaat gacagtcact aagcaaaatg gatacttcat ttttctgatc caaggaataa
     3001 atcggccagt ttctgttaac tctgagacat cacataatct tccaaccatc acatcagcaa
     3061 acgcatccaa aattctcgaa atcaagaata acgtacctac gattgcccct gaaacgccaa
     3121 gaacattcgt ataataaatc atcaagaaac tattgactaa acctaaaata aaacagttac
     3181 ctagatcacc gaacatgtag cctatcttat cggaaatccc aaattccttt ttttcttttt
     3241 ttactgtatt tgctgtaaca gcattttgtg aaagcatttg aattcctcct acctcttcta
     3301 gtaaacgttt tcaaaattat aactcttttt ttcttgtttt tatattcaca atgttggctt
     3361 tttattgcat tatcttgaca gataaaaaac aaaaaataat ctaaaaacat tgatgcataa
     3421 gattgataac tttttttaca taacaatata tacaaacaaa aaaattcact aactagtgaa
     3481 aataagttag tgaacctcat ttattaaaga attaaattac agatgatctt ttccatcata
     3541 cttgaaaaac tcaaaatcag cataacttcc tcttttttta tttagatcat gcactgctat
     3601 cccgataaaa tttccagtaa accctcctga gagtatacac atgttttttt gcggacctac
     3661 tttcttccat tcttcagttg atacgtcttt caaatgaaac tgtgctgtct ctttctttac
     3721 agtgactttc aaaaaagtct tcttttctgt gagtggaatc gtccaatctt ctatttgtgc
     3781 tactccgttt tctgattcta tcatacgtag gcattttccc ttgtcctcat tccaagtaac
     3841 ataacaataa atataattgg attcatttaa gtacagtacc agtccagcca tctgattaaa
     3901 attattaggc atgtattcaa atgctgtctc cgcatcaaaa gtaaaatccg tttgccgaat
     3961 agctaacaaa tgatgttcga aggtagattg aagagattca ccggaaatca gacgtaaaaa
     4021 acctggtcta cattttgtat cacaccaatc agcatttggc aaaatgcgtc tggcattcca
     4081 gttcttcttt agctctcctt caaatgtatc cataaactga tgatcttttt cttgttgtac
     4141 ctcttcattt gtctcaatca ttatttcttc catcggagtt gtctggctat ctttaagtct
     4201 taaccaatcg tcggacgtcc aatacacttc ttgaatagcg gtttctcttc ccaaaatagc
     4261 cgcaccgttt aatggtctgg tacaaagata tgtcatgtac catcttcctg acggggtttg
     4321 tactaagctc ccatgtcctg tacattgcaa tgtagaagca ggtttgtcac tagctgtcag
     4381 cataggaaaa ccaggatcaa gctcgtaagg accagtaata ttctttgctc ggcaaactgt
     4441 aactgaatgt cctcttcctg taccgccttc tgccgtcatc aaataataat acccgttacg
     4501 aaaatacaaa tgtggtgcct ccgttttcgc taattctgta cctgcaaata ttttatagat
     4561 gggaccatca agcttcttct tctctgcatc atattcttgt aatacgatac cgctggattt
     4621 attcggtgtg tccagacgat aatcccatag ttcattgaca agccattttt ttcccgtttc
     4681 aagatcatgg aacaaagaag gatcaaagcc gttactattt aaataaattg gttcggacca
     4741 aggacctgtg atctcagatg cagtgatcaa ataattgtgg acatctttaa acggacggcc
     4801 tgcacttttg acatctgtgt aaacaagata aaacaatcca tcagcataac tgatctgtgg
     4861 cgcccatata cttccatttg taggatttcc ttgcaaagat acttgagtgg tcaaaatatc
     4921 cgttgtatgt gaccagttga ctaaattttt cgactcatat actcggattc ctggaagcca
     4981 ttcaaaagag gagacaataa tgtaataccg ctctttcact cttaatatat taggatctgg
     5041 attgaatcct cttaaaatag gatttttcac tttgatagtc tgcatgattc aggctccttt
     5101 tctcattctt actcgatata aactgaatgc cccagctgct aaaaaagcaa gtgaaataaa
     5161 caacacaacg gcaaacagac cagtcatgtc ctgtaataat ccaaatgtat tttctaaaga
     5221 caaagttgaa tgatctacag caagcgactg ataacttttt ttaaactctg acgcagacat
     5281 attacttaaa gtaactgcta acccgccaaa gaaaatcaaa gatagactgc caccgaccat
     5341 tcctagcaat agttcccatt ttcttttcat ttctgaaccc cctgcttttc taaatgtatc
     5401 cattcaggtc ttttgatcga tgtttcataa ttgttattac gttcagagaa tttgacagtc
     5461 tgttcatttt tcttgtcatc ccaattatcc caaccagttg ggtgaacatg cccacctatc
     5521 ttacacgctt caaataagac atttgcatac ggacgccacg gtcttcctaa atagacgttt
     5581 ctagtatcag gttctgcagt caaggtacag ctttcaaaac gataccctgt tttttgattt
     5641 ttcggcgtag atgctgctgt gatgtatcca ggatttttac tggctaagct atggatatga
     5701 cactgatgaa aaacggcatc tgccccacca aatatgaaat ccaccgttcc ttcaatccag
     5761 caatattcat aggtctgacg acaatactca ggattggcag aagccggtgt acaaaaagga
     5821 gtaccatctt tttgcaaatc aggcaacgga cccgtgcata aggtatcctg ataaccagat
     5881 agtcgacagt tttttaaaga tacgcgatct cctgaattga ataaagcaac agcctgtcct
     5941 accttttctc ctggacctgc tgtattttcg atgtgaagat tttctaatac gacattcgat
     6001 ccttctaaga aaaaagtagc acttcggaaa gtccctaact ggctaccgtc aagatactcc
     6061 tgttttgcaa aacgattacc ggagataact actgttcctg ctcccacaag tttaaaattg
     6121 gataatctgc tttctatata ttcatcatat cttccttctt ttactatcaa gacctttgga
     6181 tggctatccg gcaggcctgc caaataatcg attccttctt ggatagtttc aaaatccgtc
     6241 ggggtatcta tagcattctt tccaattatc agtttgtctt tcatcctcat aaatgctccc
     6301 ttatgaattg tttccaaata tttctcattt cttgtgtttc catatgaccg cctgttaaag
     6361 aaaaagaaga aaagttttct ggactaccca ttgattgata ctttttgtcc agcccttttc
     6421 tcagcttcag tacgccttcg tccaagcaca tcgtatcgtt ttttccaact aagctaagac
     6481 gagggcgcgg agcgattttt tcttggattg ctaacgttgt ataagctgtc aatagatttg
     6541 gcacatagta ataaaaccca tgatgatcta ggcggcgatg tagcaaaagt gtttcgatgt
     6601 ccacctgtgc cgctagatca atacaaactt tgacacgaga atccaatgct gtcacccacc
     6661 agcttaataa gcctcccata gaaagaccaa tcgttgcgag ccgttgagta tctgtgtctt
     6721 cccttgtctc caaataatcg atcaagctga tcacatcata aatacgcatt ccccataacg
     6781 tttttcctgt taataaaaat tgtttgaaca actcgctttc agaaatacct ccgcgttctt
     6841 caaatcccca agcatcaatc gaccaaacag catatcccat tcctgtcagt acttctgcaa
     6901 aagatggaga agctaagtaa ggagcaccat ggatcaattc acttttcccg actgaaaaat
     6961 ctccgccgtg agaatgcagg taaaggaccg tcggaaacgg tccttctttt tctggataag
     7021 catagagggc tggtactgtt tccaattcat ttaagtacaa ttgatagtat tcaagcataa
     7081 aaccgttttg tttttctcgg tataatcgtt ttccactagg ggtatgtctg ctagatggag
     7141 cacctaaaaa atcattcaac tgcataagca aagtttttac gaacaaccag ttcatccata
     7201 ttttctgatt gatttgattg gaatttctca atactgattt ctttagtatt ttctaataga
     7261 aatgctggtc cctcgtgatt ttcaatcgac atctggttaa aggaaacctt acccgcaaag
     7321 ccaatataaa atccttgtct gctcatttcc tctattcctg tcatcatagc aggaacaccg
     7381 ggaactgcat cttgggccat cgagacatcg atattgtcaa atgtgatttc ttgtatgaat
     7441 tgttccgcta atccataaat aaaacctgca gaagcatgga cattccttgc cgtgatattc
     7501 gaaaaatgga tccttctgaa tgctgatgtc cgttcatcta tcggataagc ctttttttcc
     7561 catacatacg gttctttccc tcgcggacca cagaaataat aaagattcag tataaatgga
     7621 cacatcacat tatccatgac tatattggat actcgaatat cttcaacgat cccgcctcga
     7681 cctcgtctag atttcaatcg tattcctcga tcagtttctt ggaagataca atttgaaatg
     7741 gtaatattac gaatactacc actcatttca cttcctaata cgacaccgcc atgtccatgg
     7801 accatcgtgc aatttgtgat cgtgatattt tcgcaagcga tcctttcgta cgtatcttca
     7861 gtccctgcct tgattgcaat acagtcatct cccacgtcaa tatggcaatt actaatacgc
     7921 acatttttgc atgattctgg atcaattccg tctgtatttg gtgaatccgc tgggttcaag
     7981 atcgtcaagt tatcaaacgt tgcattactg caaagaatcg ggttgatcgt ccaacttggt
     8041 gactggatca atttaatatc tttcacagta attcgatgac agttatggaa actcatcaat
     8101 ttaggacgag gataagcgag attatctggt tcatttctaa aagtatgcca ccattttttt
     8161 ccatttccat ctaatgtacc gaaaccagtg acagagatgt tctctacatt ttgagcatag
     8221 atacaggaag cataaacttt tcgatggact ccttcccaac gtgaatgaac aacaggataa
     8281 tcttttggat cgtcagagaa tttcagaacc gctcctgcgc ttaaatgaag ttcgacattg
     8341 ctttttaaaa ataaagctcc tgttagaaat tcacctgctg gaacaactac ggtcccgcct
     8401 ccgtcacttg ctgcagcatc aatggcttgt tgtattgctt cagtattcaa ttcatcaatt
     8461 gatgcgccaa atgtcaaaat atcatacata tttataatgc ctccacttca atcaatgctt
     8521 gcaagaatgc accaacgcct ttttgatcat tacaaataat tggttcactg atgtagtaag
     8581 catatgaacc atctcgctga tctgctccgc ctaaccctgc tacttgacag tttttattca
     8641 agttcagcca gccttctttt gtttccagaa caaattcatc aagtaatcct tgatgtgatt
     8701 tcttcacttg tggaagccat tcttctttgt tcagcagtcc caaacgtatt cctttagcca
     8761 ttgcgtaaac aaacatacta ctgccggaag cttccagata atttcctttc cgttttgttt
     8821 ctgttgttac ttgataccat gtcccgctgt tttcttcttg atatggaagt aatgcagcca
     8881 gtgtcttttc tagaatttct ttcagcaaag aacaatctgt ttcttcatga agtaattcat
     8941 aggtatctgc tgcagccatc aaataccagc caatcgatcg gctccaaaaa tgatgggata
     9001 gacctgtttt tggatcagcc catggttgga ccttcttttc atcccatgca tgaatcagca
     9061 aatttgtttt tggatcgaat agatgtttat aactgatttc aaactgtctc aaaacatctt
     9121 ggtaatcttt ttcttcacta aaattctgga taaattcagc ataaaaagga gaacccatat
     9181 ataagccatc caaccaaatt tgataaggat aaatttcttt atgccaaaaa gctccttcgg
     9241 atgtgcgtgg atggtttgcc aactgctggg aaaggagttc tgctgctttt ttatattttt
     9301 cttcgcctgt ttctttgtac aataaaaaga aaagctttcc tgtatttaca tggtcgatat
     9361 tgtattcttc aacgctgtag ccacggatcg ttccatcttc ttgcacgaaa tagtcgatat
     9421 tgtcttttat gaaatcaaaa taaatttttt cttgggttcg ttcccaaagt aattggaacc
     9481 ctttaagtac gacgccatag tcataagacc attttccttt ataccacttt tcttcatata
     9541 agcgaggtgt tctttccatg atactttttg ctaatttctt tgaccagttt tccattattt
     9601 gctctccttt aaaaattaaa ataggatttg ggacaaatac caagaagtat ttgtcccaat
     9661 cgtctatatt actgtgccgc tgctttgtat gcttcctcgt actcttgtgt gattcgatcg
     9721 cctccttgtg ctttccagtc ttctacagct tttttgaatc catcttcgtc aagctgtccc
     9781 atgatgtatt gcaccgtagc atcaatgacg attttttcaa tttctgatcc tacttcattg
     9841 ttcgtcggtg aatccaatgg cacagaagga tccattacag caaattcttc attttctttg
     9901 atcaattgat tagagaattc tttttcaggg tctgtatctt tgaaagagaa cgtcacttca
     9961 ctaggacgag agcttgataa cggttgcacc tcttgttgcc aaagatccat atcgataaat
    10021 tcgatagaac catcatcatt caattcataa tgcgttcctt cgataccgcc agtcatcaat
    10081 ttatacacat cttcttctaa aagatcatca acaaattgaa gtaatttctt caattgtgct
    10141 tcgtctttta cttgagattt gggaaatgct agcaagccgc caataccatt tccttctgac
    10201 caaacatgat aaccgccgcc ttcaccatct gagatcttgt ttacaggcac taattccata
    10261 tcatcttgaa taccttgacc catcgtcttc agattcttga tatccaccat tccagtgtag
    10321 attccagttc ttccttgtgc aaattgttct tgctgatcag tcttttgggt aactgcaaag
    10381 tcttgtgcca aatagccatt ctcaaataga tctcttgaaa aattcaaagc tttcatatac
    10441 tcttctgtat caaattctgg agtgaatttg ccattatcgt ctacagccca gccatttggt
    10501 gctccaaaat aagaagtgaa aagtttaaag ctggtataac gaatatcact aggcgcacga
    10561 tcgccaaaac caactgtgtc gtccacacca tttccatcag gatcgttttc tgtaaattgt
    10621 ttagctactt cataaagctc atccatggta gttggaacat ctagtcctag attatccaac
    10681 cagtcttttc gaatgactaa gccagcacga gcgtagtctt tttgtatcgg tacgccgtac
    10741 aaggcaccgt cgatactcgc agcttcgatt ctatcttcag aaatttgact taaattttta
    10801 tagtctttta aatattctga tacatcccag aatacgcctg attttaacgc attgcggaca
    10861 gaagagtttt tcaacatcgc aatttgaagt gtaacgatat ctcctagttc atcagaagcc
    10921 aatgcagttg ttaatctttc ttcttttgaa gcatcaggaa tccagttgaa tgtcagttcc
    10981 gtatcggttt tttcttcgat caagttcaca atcgtgtctg taggcggtga agcatgatgc
    11041 aaaatattta accaagtgat tttagctttt ccatcttctg tctctgaaga actgttactt
    11101 gaactgctgc cgcatgcggc aagtgctaga attcctgcaa aactaagacc taattttacg
    11161 agcgttgctt ttttcataaa ttttctcctt cactgtttta ataatatttt tgttttcttc
    11221 tgttttttct gtatatgagt tcttccattc caaatggcaa aatatagaat ttgctgtcca
    11281 cgtgactgcg gaaaagaaga gactgccacc gataaaggtt aaaacacctg gcattgtttg
    11341 gatgatcatc agataaatcc ctaccatact taatatcaac actaatgagt aatgaagatg
    11401 tgagaatccg aataaaaatg ccattttcat tttgaaaaaa tatcctttcc aatcataatg
    11461 agccatgatt gggaaaatat agagtgctga gagcacatat atgaacgcag caatatacaa
    11521 agcgatccta agataccaat tgtgtatgaa agaaagatcc acaagtaaaa caatcccgat
    11581 ggcgccatat atccagctca tcagcaaggt ttcacgatag ttttctttaa aatatgtgaa
    11641 gtacgttttc gtcaaaggaa acgtttcttt tgagcgcagc cattttctaa tcactgcaac
    11701 catcgcatac gatgcaggac cgaaagtaaa aactcccaaa cctgcgatga ctaaaccgcc
    11761 ccacagaaaa ttcaaataaa ccaactgtaa aatacgattt agccttccgt ttattttatc
    11821 taatgactgc agcatatctt tccctctctt tctatcttag taaacgccgt cttctcctag
    11881 ctttttggca atcttattag ctaaaattac cataaacaat cctacgaccc ctttaaacaa
    11941 tcccattgct gtactgaaac ttaactgtcc attcttcaat ccagctgtat aaatataggt
    12001 gtcgaaaatt tctgcaacgc ttcgattcaa tgaattcaat aacaagtaca tatgctcgaa
    12061 ccctaagtct aatgtctgac cgatttttag aatcagcaag gtaatgatta ctggacgaat
    12121 tgccggcaat gtaacatgcc atgttttgcg taagcgtcct gctccatcca tttctgcagc
    12181 ttcatacaac tgtgtatcga ctgcagttat cgctgaaagg tagatgatcg tagaccagcc
    12241 caactctttc cagatcactt gtccgatata tactgtgcgt gtccattcag gggatgttag
    12301 aaaactgatt ttttcaaatc ccattgttgc aaggaattca ttcaataccc ctccgtcaac
    12361 attcaaaaat acataagtaa tcgaaacaat gattacccaa gacatgaagt gagggatgta
    12421 aatgatcgtt tgaatcccgt ttttcaatcg tttgttcgtt acttcattta atagtaaaga
    12481 caaaatgatt ggcatcggaa aaaacacgaa gatatttaat ccgaacaaga tcaacgtatt
    12541 tcttaataat gtaaagaatg tcggttctgt aaacaaacga atgaaatgtt tgaaaccgac
    12601 ccaaggactt cccattattc ctaaaaatgg ttgataatct tgaaaagcaa taacgagtcc
    12661 ccccatagga agatacctaa aaatcaagaa ataaaggact cccggcagaa tcatcacata
    12721 taaaaattta ttcgttttga ttcctgcaat tatttttttt cgtcttctga gcttttcttc
    12781 ttttttcgat agcgtcagtt gaaatggttc ttgtttcttt acactttcca taagcccctc
    12841 cttagttttg tgaatgtttg ctgcttatga cttcatgata gataactatc tgaattacgt
    12901 atataatcat ttttatcgta agtaaaaacg cttacatagc aatgattttt gtgctataca
    12961 aaacgataaa gtgtattttt tcacaaataa actacgcata gcaaaccttc tatttttttc
    13021 tatctgacac ttagcatagg aaatgattat atacgtaatc tttcaccgat gataaattga
    13081 acatatagaa acagaaacat ttaatttatt ttgaggagga gcctatctat atgaaaaaga
    13141 aagtctctat aggagaaaga agttttacac ttttcaacaa tacgtttcta attttgctag
    13201 ctttgatctg tatcgttcct tttttaaata tcatcgctac atcttttgct tctacacaag
    13261 aagtcgtcgc gaaaaagttt atcctttttc ctactacctt ttctttagac gcgtatcgct
    13321 acattctttc tacgccgacc atttttagag cacttgctgt ttcgattggt gttacaggtg
    13381 tcggaacgat cgtcagtatg tgtgcaactt cactgatggc ctacggtctt tccagaaagt
    13441 atttgtttgg tcgaggtttc gtcaactttc ttgttgtatt ttctatgttg ttcagcgggg
    13501 ggatgattcc aacgttctta gttgttcgtt ctctagggct ggtcaattct tactgggcca
    13561 tgatcctgcc tgtggctgtt aatgcaatga atatgatcat tatgagaaac tttttccaag
    13621 ccttgccgga tagtttggaa gaatcagcaa aaatggatgg ttgcacagat tttggtgtat
    13681 ttttcaaaat tatgctgcca ttagctttac cgtctattgc tactatctcg cttttttatg
    13741 ctgttactta ctggaacact tatatgactg ctattttgta tatcaacgat tcatctaaat
    13801 ggccgataca gattctttta cgccaaatcg tcattgtatc aagtgggatg caagcagaaa
    13861 gtagtgccgt tgatgtgatt ccaccagcac aaacagttaa aatggctgtt atcgttattg
    13921 caacagtgcc tatgctgatt gtttatcctt ttgttcagaa atattttgtc aaaggagcac
    13981 tcgtaggttc tgtcaaaggg tgattatgta ctgaacgcaa aatggtagtt gtgtcagaag
    14041 tggtcagctt caagaaataa gaaggcattt acgaaaattg cttcttaaat ttttgtgaaa
    14101 tttcggctta tttttcgaag aatctactcc tggaacaccg tgtatcagag gttgtgaaag
    14161 agacgttcag ccttgagcga tgataaaaac tctcacaaac attgcgacga gtaacccaca
    14221 ggagcaataa gaagcgattt tgaaaaatag cttcccatat ttcacaaaat tatgccttat
    14281 tgtcgatagc ctgtctcttg aacgccattt attcgtaaaa aagaactgtg acaagacttt
    14341 tgtcacagtt ctttttgcgt gcttagcctt gaaatttaac tatccataaa tacaaatact
    14401 agggttattc taacttcttt tattgcttga atcagtccac aagaaaaaca gcctcttgat
    14461 taaacggcgt ttatcttgtt gattctgcgg caataaaatc agccagcagc aaaacatgaa
    14521 gtgctgtttt ttgctgtcct cttttattgc ttgaatcaga tcacaagaaa aacagcctct
    14581 tgattcacaa atattttttt cgatattctc ccggcgtaat cgattccttc tttttaaaga
    14641 aacgaataaa attttgcgga tttcgatatt gcaatctttc tgcaatctct tttacggaga
    14701 ggttagtctc tttcaaccat ttttttgcta cctctaaacg atgattttga acaaaatcac
    14761 caaatttttc tcctgtttcc tttttaaata cattacttaa atagttaggg ttataatgca
    14821 acctatcagc gatcacatct aaagacagat cacgatcata ttctgtgtag acgatatgca
    14881 taatattctc cgacaaattt ttaaattcat gatcagtgat tgcttgagag cattctgtga
    14941 ttggcagaac taattgttct aaaacaagtt tttctagttc tttgggatga taattgttca
    15001 gtgcttttac ataaatttgt ttcatgttat caaagttttt tgaatctact cccaataact
    15061 gtcctaattg aacgagttca ttgatcaagc ggaccgaaac tacttcccga ctcaaaggat
    15121 ttttattttg tgcaaacaat gcatcaatca attcatgtac taaattcttc acttcctgat
    15181 ttccagaacg aatggcttca aacaatcgat tttgttcttc tatcggatat ctaataagtg
    15241 ttttttcatg agcagcagga acgatttcct gataaaaaat aattgaactt ggaccagtat
    15301 ttacacgata atacagggct tcttttgccc gatcaaccga ttgcttgctt tcattcagcg
    15361 tttcgaaccg gttactgatg cctatactga tagttaaatt caagtattct tttacacgtt
    15421 tttgaatgag tcggcaatac tccatgactt ttttgcttgc ttctgcatca tctttatcca
    15481 ttcgataaat agtggcttgc atttcttcat tcaaaacgat cggcagcatt cgattttcct
    15541 ttggcacaat ttccgtgatc atgttgttga tcgctaaaag tagcaaatca cgctccccac
    15601 cgtgactatc ttctaacaga tcgatttgaa ccaaagctgt ataatagcag tcattttgag
    15661 aactataacc aaattgctgc aaccgctgat ctagttctcg cctttctact cgatttctaa
    15721 ataaactaag tacaaatagc gtttccagct gtggcttttg ggtaactaag tgtgcactta
    15781 acgcttcttt ttctcctatg atccgactga ctgattgagc gaccaaatct agttctttcc
    15841 cactgaatcc ttttgattta agattcagac gttcctgtat ttgagaaatc ggacgggcaa
    15901 atctgtccga aaataagtag gaaaaaagac caatgagtcc taccagtgtt aaagacactg
    15961 caactagccc gattctcaga ttgcggatca ttgcgccaat tgcactagag tcaacttcta
    16021 atctgtaaat ccaattatta taatctgatt tcagtactat atacgtttta tctttttctc
    16081 ttatcacttt cagctgattg taatctagat ccacgtccgt taatacagtt ggttgctctt
    16141 tattttttac tgtctgagta gtaaaaaggt tgccaacttc gttttcaata gaaagtatgt
    16201 cttctccact ttcaccaaca acttgttcta ttgtatgttt ctctatcgta gcaattccca
    16261 atgcatattt ttctttttca aacattggca aagaaatcac catttcgatt cctttgtttt
    16321 tcttttgcca aaataaatta tttttgttat ttatgtactt ctgttgatac ttttcaactt
    16381 cctcttcggt cagttgactc aacgatccat tgattactcc ccatttacca gccaaactga
    16441 ctaaatcata attattatca tccataacaa tcgtttctat aaaatttagt tctttcctga
    16501 tttcagaata agtggagtaa tctgtatatg tcagcggatg cttgaatatg tccgagaaat
    16561 ttttggtcga accatacgta gaaaacgaat attcaatcgt tctaattttc cattcaacgt
    16621 tagttttaac ttgcctgagc aaattctttt tgtctgttaa ataactcgat tcgatcgatt
    16681 cataggtatt ctggtaaatg aataaactaa atcctatgac aagtacggct cctaataaaa
    16741 acatcggtaa aaatatttta taaaatactg tacttttctt cattttcttc ctctcctcct
    16801 tttaaaataa aaggctttca tttttctgta aaattgatac tcatctaatt aaatgagcat
    16861 tccccgcttt caagaatagc ataattaaaa ataaaaatcc aagtaatttt taacgtgtgc
    16921 aatcttttca tatcaaagat ctattgactt atcgtagtta tcgtaatatg atgaatgcgt
    16981 taacaaaaag tgaaaaagta aggaaaatga tggaatggta acgatcaaag atatcgctaa
    17041 agcagctggc gtttctcata cgacagtttc tcgtgctttg aataacagca gtttaataaa
    17101 aaatgaaaca aaacaaaaaa tacgacaact agctaaggaa atgaattatt cgccaaacta
    17161 tagtgcaaaa ggtttagtga atcaaaaaaa atatctaatc ggactatttt tctcaagttt
    17221 gcataaagga acttcatcaa atttcctagc agattccatt gcaggcatcc attcagtatt
    17281 agacacaaat tacagtttat ctgttgaaag tatcgatgtt gttgatttaa cagaaatcaa
    17341 cctgcaacgc tacgatggac tgatcgttat gagtcaaagt gatgatgatc agcctttcat
    17401 cgactatctc aaagaaaaag aatttccttt cgttgttgtc aatcgtcaca tcaatgatcc
    17461 agcggttatc aacgtcactg ccgatgatgc ggccggtgtt atgcaggcag tagattacgg
    17521 tattggatgc ggacatacga agatcgctta tattggcgga aagaaaaatt ttcgttcgac
    17581 aaaagaacgg gaaaaagggg tattgaaaag tctaaaaaaa gcgagcatcc ctgtcaatct
    17641 agcctatttt ttaacaggag attacagctt agaaagcggc ctccaaaaca tggaatacct
    17701 attatcactt tctgacctgc ctactctggt tttttgcggc aacgacgaca tagcgattgg
    17761 tgcattgaga gctgtacatt tagctggcct ccgtgttccc cagaacattt ctctgatcgg
    17821 gttcgatgat tctccagtcg tctcctatct caatccgccg cttaccaccg tacgtaagcc
    17881 tttgaaagaa atgtgtcaag aaggaacaaa gcttttacta gatttgatcg aaggcaggac
    17941 gatcgaacaa tctaaaattg agctctccac cttgttgatc cttcgtgagt cgatcaatta
    18001 cttgtaaact acaagtaatt ttatataaaa atgttaacgt gtgcataaca cagaaaggaa
    18061 gtttatatga aaaaactgac aaaagaatta gtgaaaaaaa acgaagcacc tgtaaaagtt
    18121 cttcagtttg gtgaaggcaa ttttatgcgt ggatttattg attggcagat tcagcagctg
    18181 aataaccaac aattgtttaa aggtaatgtt gcaatcattc aacctttaga acaaggtctt
    18241 ggaaatatga tgaaccagca agataattta tatacggtca ttttacaagg actcagcaat
    18301 ggcgaaatcg ttgatacttc cgagattatc accgtagtag aacaaatgat caatccttat
    18361 gatgaatggg atgcttatct atctctagca gaaaatgacg acttggccta tatcgtctcc
    18421 aatacaacag aggcaggaat ccaattcgtg gagactgata atttaacaga tactccccca
    18481 cagagcttcc cgggcaaact gacagccttt ttataccgac gtttcaaatt aaacaaagct
    18541 ggctttacca tcattccttg cgaactgatt gacagaaacg gcgaacgtct aaaagaaatc
    18601 attttacgct acgcagaaaa atgggattta gaacctgctt ttgttgagtg gttagaaaaa
    18661 gaaaatgttt tctgttgtag tttagttgat cgcatcgtcc caggttatcc tcgcgaagat
    18721 gcaggtgttt tcaatcaacg gcataactat gaagatcaat tgatggtcaa agcagaacca
    18781 ttcatgcttt gggtgatcga agggcctaaa gaattggaga atcaactacc attcaaacag
    18841 gctggcttga atgtcatcat cacagatgat atgactcctt atcgtgaacg taaggtgcat
    18901 ttgcttaatg gaccgcatac agcgatggtc cctcttgctt tgttggcgga attggaaact
    18961 gtagaagaag taatgaaaga tcctttattc tccgcatatg ttgatcagtt attcaatcta
    19021 gaattgattc ctatgctttc tttacctaaa gatgaattag ccatttatgc tgaccaaatc
    19081 aaagaacgtt tcttgaatcc ttttgcccat cacaaattag aagcgatttc attaaatagt
    19141 gtttcaaagt tcagcacccg tctgcttcca gtgttcaaga agtatatcga agaacaaaat
    19201 caggtaccac cgttaatcac tgtttcacta gctgcgctac ttcttatgta tcgaggcgat
    19261 caagtaaagc cacatgatga tgaaaagacg ataagcgaat ttactgatgc ttggtctgat
    19321 aatggaacag ctattcctcg attattgcaa aacgctgcgc tttggggaga agatttgtct
    19381 caaataccga atgtgacaga tacagttcaa gaaatagctg caaagatcga tcaaaaaggt
    19441 gtccggtcag tattacaaga aatgaaagga acgatggtcc atgcttgaaa ccctgcaacc
    19501 aacaatgaaa ttaaatcgac gagacagtgt ggtcgtcgca ttaaccccta ttccaaaaca
    19561 aacacaactg acgattgatc agcaaacgat caccactctt gaagatatcc cgcaaggtca
    19621 taagattgca ttgggtgatt tgaaagctgg agacaacgtg atcaaatatg gctatccaat
    19681 cggtcatgtg acgacagacg taactgccgg tcaatggctg cacactcata atgtaaaaac
    19741 caatctttct ggtgaattgg attatcgata tgaaaaagat gtccatccaa gtcattacct
    19801 ttttgagaac cgaacatttc aaggttactt gcgaaaaaat ggaaaagtag ggattcgtaa
    19861 tgatttgttt ttagtaccta ccgttgggtg tgtgaatggc attgctgaac tgatcgtcaa
    19921 acagttcaag gaaaaacatc cagatctggg acagtttgac catattacga ttttaaagca
    19981 tccttatggc tgttcgcagc ttggaaaaga tcatcaaaat actcgagaaa ttttagcgga
    20041 cgcagtaaat catcccaatg ccggaggagt tttagtattt ggattaggtt gtgagaacaa
    20101 tacagttcct gaattcaaaa aaattttagg tgaatatgat gaagaacgag tgaaatttct
    20161 agtggctcaa gatgtttacg atgagatcga acaaggtgtg gctctattag aagagctttt
    20221 aacagcggcg gaaaatgacc agcgcatatc agtcccgctc tctaagttga atgtcggttt
    20281 gaaatgcggc ggttctgatg gtctatcggg aataactgct aatcctttac ttggtgcatt
    20341 ttctgactac ttgattgctc aaggaggcag cacgatctta acagaagtgc cagaaatgtt
    20401 tggcgcagaa caagtattga tggcacgagc ggaaaatgaa gaagtttttg actcaatcgt
    20461 tgacttgatc aatgacttca aacagtattt cttgtcttac ggggaaccag tttacgaaaa
    20521 cccatctcct ggtaataaag caggtgggat cactacatta gaagataagt ctttaggctg
    20581 cacgcaaaaa tcaggaagct ctcctgtcgt tgatgtgcta caatatggcg aaaaaatcag
    20641 aaaaccaggg cttagtttat tgcaagctcc cgggaatgat cttgtagctg cctctgctct
    20701 tgcttcatcc gattgccagt tggtcttgtt taccacagga agagggactc cgtttggctc
    20761 atatgtccca acggtcaagg tatctacgaa tacaactctt tttgaacgca aaggtcattg
    20821 gatggatttt aatgcaggcg tcttattaga acaaccaatg gaagtaatct tagaatcgtt
    20881 tgttcaaaaa atcatcgctg tagctagtgg agaagaaacg aaaaatgaac aaaatgacgt
    20941 tcgagaaatt gccattttta aaaacggagt aacactttga ttttcataaa acagtataaa
    21001 aagaaagaag gaagatttat gtttttatct gatgattttt tattaaaaga cgattgggcg
    21061 aaaaagcttt accattccta cgcaaaaaac atgcccatta ttgattatca ctgtcactta
    21121 gatccaaaag aaatttacga aaacaacaat ttcagcaatc tgacagaagc ttggttagga
    21181 ggcgatcatt acaaatggcg cttgatgcga gcttgcggcg tgcctgaaga aaaaatcaca
    21241 ggaaatgctt ctgattttga aaaattttta gcttggtgtc aaaccgtacc aaaaattatc
    21301 ggaaatccgc tttacagttg gtcacatctt gaattgaagc gtttcttcgg tattgacttg
    21361 ttgataaatg aagaaaatgc agagaaaatt tggacacaag caaatgaaat tttggcagct
    21421 cctgattttc gccgtcggga aatcgcaaaa aaatcgaatg tagaagtgat ttgtacaaca
    21481 gatgatcccg cagacgactt gcactatcat cagttgcttg ctcatgaaga accagatttg
    21541 aaggttctac cttcattccg tccagataaa gcactcaata ttgaaaaaga aggatttaat
    21601 gcatgggtca cactactgga agaagcagct gaccaaacga tcaccaccta tcaagaactg
    21661 atagaagtct tagggcagcg gatagaatac ttccatcaac atggatgtcg tgtttccgac
    21721 cacgctttag acatcttacg ctataaagaa gcggatgaaa cagtattaga agagattttt
    21781 caaaaagcac gagctaacaa actattatct tcagatgaaa tcgatgctta tcttacagaa
    21841 acactgatac atttgaccca cttctatcat tctcataatt ggacgatgca gctgcacatc
    21901 catgcttatc gtaactgtaa tacacaaatg ttggaaaaat tagggcccga taccggctat
    21961 gatggaatga atgatctttc tttgactatt cctctgcaaa aattattgaa ccgtgcagaa
    22021 gaaacggatc agttgccaaa gacgatcctt tattcattga atccgaatga ctatcctgcg
    22081 attttagctt tgatgggctg tttccaaaaa gaacagaatg gaaaactgca gttaggttct
    22141 ggatggtggt acaacgatac tcgagctggt atgcgcgatc aattgacaca atttgctgat
    22201 ggtagtgctt tggggaattt tgtcggcatg ctgacagatt caagaagttt cctgtcctac
    22261 actagacatg aatatttccg tcgtgttctt tgtgaatttt taggcgaaat ggtcatgcga
    22321 ggagaagcac ctgaagatga acaactttta ggaagtctag ttcaagcgat tagttataca
    22381 aatgctaaaa attactttgg cttttttgcc taattgatta atagtaacag taacgaatca
    22441 aaaacaggat agtgaaataa cggaatccgt ttatccacgt tttagagaag aagacggacc
    22501 aa
//
LOCUS       DACGDM010000035        22031 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.035, whole genome shotgun sequence.
ACCESSION   DACGDM010000035 DACGDM010000000
VERSION     DACGDM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.035"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            367..555
                     /locus_tag="IXR05_001475"
     CDS             367..555
                     /locus_tag="IXR05_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259987.1"
                     /translation="MELIVFTNNGQTYHFYEVENFKPTTTGFSFIYTGKATGVTRSAT
                     FNNTSTAGYALAEVQNES"
     gene            545..805
                     /locus_tag="IXR05_001476"
     CDS             545..805
                     /locus_tag="IXR05_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259988.1"
                     /translation="MNHEKFIEKCKAIVRERIENEIADLSGAVPEFSIFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            846..1073
                     /locus_tag="IXR05_001477"
     CDS             846..1073
                     /locus_tag="IXR05_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259989.1"
                     /translation="MRNYWYVSLTNEYPRTIGDCSVRVVRSVQIKGKYSIVEMLREAT
                     PNEVDKCKLIYCGHGYWKDEYIQYNIERYIK"
     gene            1138..1710
                     /locus_tag="IXR05_001478"
     CDS             1138..1710
                     /locus_tag="IXR05_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259990.1"
                     /translation="MKLKDYIREGYNVVTAPNLAYKIQEDYPNALVFTDRALDAIPIG
                     KLLVDRFYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWDTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            1711..2022
                     /locus_tag="IXR05_001479"
     CDS             1711..2022
                     /locus_tag="IXR05_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4259991.1"
                     /translation="MIDVSSKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            2013..2273
                     /locus_tag="IXR05_001480"
     CDS             2013..2273
                     /locus_tag="IXR05_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259992.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEGTTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            2434..2793
                     /locus_tag="IXR05_001481"
     CDS             2434..2793
                     /locus_tag="IXR05_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259993.1"
                     /translation="MADLQERNRLVSAEERRLNKLFKDIDKDKKKVVSGLITQAARLK
                     ILLDEMWIDISEKGDYELFSQSENQKPYERERPVAKQYNSRDQAYQRVIKQLTDYLPE
                     EKREPTKNAALDGSDLL"
     gene            2790..4433
                     /locus_tag="IXR05_001482"
     CDS             2790..4433
                     /locus_tag="IXR05_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4259994.1"
                     /translation="MTTLKPFYFDEYVDLYEKGVIPFNKERIQLITYLKNEVLVRDDI
                     YFDEEMIQKFIKYTEKNFFPLAKYQKFITPFIFCYQKEDDEVFFDEILNSIARGGGKN
                     GFMSARDSFFISPLYGVRNYDVTITANSEKQGKVSFKEVYEMVQMRKLEKQFYLTKMA
                     IVNNVTNSIFSYRTNNPKTMDSARDGCLEFDEIHQFESSDLVDIQRSGLGKIKHPRTF
                     YNGTNGHVREGFYDKMLERAQKIFSGENKNDRLFPFICKLDNIDEMDNPKMWSKANPM
                     FEEDSAYSKRLFSTVMKEYKKLEDEPSGRREFVVKRMNFTEGDAESDITTHEKLMATK
                     QELPNLNGRSCVAGFDYASIRDFATVGLLFKIDDKFIWQQHSFARKKFLDTFKLKAPI
                     KDWEKKGLVTIVDEPSIDPRHLIDWLNEKRKIHQIEIVCADGFRMDLLKPLLEKESYN
                     FEFIRNIRGVQSKVAPIIEDGFANERFIFGDDPMMRWYTNNSFIKEDKLGNKTFLKKE
                     PVRRKTDGFHAFLAALYKREEITDMDYEEAFDMLDEIEF"
     gene            4468..5550
                     /locus_tag="IXR05_001483"
     CDS             4468..5550
                     /locus_tag="IXR05_001483"
                     /inference="COORDINATES: protein motif:HMM:NF028182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4259995.1"
                     /translation="MKKRYFLFVTIFIIIAICVLTVFLPQITEYLNYRIFTTKVDDSV
                     TSLSRLEFIKICASVFGPILTVMVFVNTLNMQKKTEQKQNELEVKQAKAENERAKKEL
                     LTQIDREFYFLLNMFIEIQKDQNAKQAVIALQKLAIFNEKGFNQDYAFTSKDLSDSEI
                     GSTIEQSGPLKGTVEYIKFETFDVSKSMGNYQTKTKDVATSLHDQKVAILNEQYEKMQ
                     IYLGRYFKMFHRIVKTLNEYYDDYNDFDVKRYTKYIGTLRTQISPAEFQVILFNSLYI
                     KRGFGLGIQLIGSGFFGDDFDFETNQHFETSINEQWFLSLSTVDSDNSIKRQKLSEYI
                     KELGSVEYKKIANFESLYKLFNETKL"
     gene            5594..6766
                     /locus_tag="IXR05_001484"
     CDS             5594..6766
                     /locus_tag="IXR05_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4259996.1"
                     /translation="MSLFDIFKQSIRNEEPSEWIPDFVYGEEVSARAYLKIMAKNTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWNMSDVIYMEYNNEELERFTR
                     GLFEDYAALFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDRIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIDDVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            6753..7457
                     /locus_tag="IXR05_001485"
     CDS             6753..7457
                     /locus_tag="IXR05_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAQ4259997.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            7462..8622
                     /locus_tag="IXR05_001486"
     CDS             7462..8622
                     /locus_tag="IXR05_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4259998.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTAEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVKYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            8698..8976
                     /locus_tag="IXR05_001487"
     CDS             8698..8976
                     /locus_tag="IXR05_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAQ4259999.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            8957..9328
                     /locus_tag="IXR05_001488"
     CDS             8957..9328
                     /locus_tag="IXR05_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAQ4260000.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            9344..9748
                     /locus_tag="IXR05_001489"
     CDS             9344..9748
                     /locus_tag="IXR05_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260001.1"
                     /translation="MSNVKFEGVQETIQALEKKYGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIAEVVRKNATYRDYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSELLYFDAVGEEVKKSL"
     gene            9745..10155
                     /locus_tag="IXR05_001490"
     CDS             9745..10155
                     /locus_tag="IXR05_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260002.1"
                     /translation="MKDMLNIIYEALCLNEYIHSMTYNENTEQYRIKFYEQPETADKT
                     GPMITIRPVDTPNEAYHGSNKELSVEHMIQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFTETNRFVDARRYEGNTKIYDTEY"
     gene            10216..10803
                     /locus_tag="IXR05_001491"
     CDS             10216..10803
                     /locus_tag="IXR05_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4260003.1"
                     /translation="MTLVGFKKMTIGVFDSTGKIPAANLYVIEGEQNKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITGLKEMVFPAAGE"
     gene            10876..11343
                     /locus_tag="IXR05_001492"
     CDS             10876..11343
                     /locus_tag="IXR05_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HAQ4260004.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            11389..11697
                     /locus_tag="IXR05_001493"
     CDS             11389..11697
                     /locus_tag="IXR05_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260005.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            11892..18626
                     /locus_tag="IXR05_001494"
     CDS             11892..18626
                     /locus_tag="IXR05_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAQ4260006.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGFTGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRNLATQLPGSHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKILKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKAMDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDSTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDTVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPSDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPKNAKGTNFHP
                     GGAAMVNDQKGPTYEELITLPSGETFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYAD
                     GIGNITTVSSTLNLDALILAINELTTVLRTQLMAGTTDAKDTKLSDETKVADPIIPDS
                     LSEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGAT
                     WNKNLLNGWNSLTGTFIATINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYG
                     SFIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMV
                     GGIGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHE
                     EYVQMPDGRSFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDL
                     LDDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDG
                     AVNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRY
                     TAAANYAFEKFPSKIAYVITNGRVRDRMGLSGTRSSGQWTNWPDGDHFDHIHLNGSMG
                     SGDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGN
                     DGLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIG
                     KGHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGSNKKETKS
                     EINSVDNRHILQAIEKQSRMTNDLLSLLLSFFKSNNRSDKELALDIQKILIRRT"
     gene            18630..19502
                     /locus_tag="IXR05_001495"
     CDS             18630..19502
                     /locus_tag="IXR05_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260007.1"
                     /translation="MRTVILRNKLNEEIDLSTEDYFATEMSNLGFEVTKEHIGQWGSF
                     REIGESIELSEFQSSVMISVHGFREQQLYGSLVEFLANGPFELEFSFDSETMIRKCSL
                     KSLSKTEIDSQSSLLTDTLNLYFTSSWYSIKREKLIQNSTSLNTRGKVYSFVRPYVYT
                     KNVWEKKGVFKFSNNSVYLTNSTERMSPLKIRIIGECSNPYWEVIQNSKVVASDGYFI
                     NMKDTQILEVSSLLEDQTAILKDVGGVESSVYQQQDFTKSNFVQAPLGEFSVVFHVGH
                     ANVEIELYEERDLF"
     gene            19499..20126
                     /locus_tag="IXR05_001496"
                     /pseudo
     CDS             19499..20126
                     /locus_tag="IXR05_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176402.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            20087..20548
                     /locus_tag="IXR05_001497"
     CDS             20087..20548
                     /locus_tag="IXR05_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260008.1"
                     /translation="MQSPGPGNENKLLIVDKAMKDIENPLVLSTWYLDDENNLTQDST
                     NKNIALPTVNLVNIYDQTQEDRPSYEEVAKSELKGNAYSHEIKVNVVLNARNINVENI
                     ETGMLATIVYKEQTYKSVLTAWRISSSKKNIELTFGNVRSRFMDYFEDNGG"
     gene            20552..21376
                     /locus_tag="IXR05_001498"
     CDS             20552..21376
                     /locus_tag="IXR05_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260009.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERI
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            21394..21939
                     /locus_tag="IXR05_001499"
                     /pseudo
     CDS             21394..21939
                     /locus_tag="IXR05_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176405.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
BASE COUNT         7878 a         3297 c         4671 g         6185 t
ORIGIN      
        1 cttctaaatt gttcttatta tctatcatca gttgctgtct attgtcatta tgtcactgtg
       61 gtggaaaggt gtatcgctca tctaaaattt aggtgcaaac tgcaaggttc gattccttgc
      121 cagtgacttt ggtaaccgag gcatcggcgg tttaaaaata taggggtgcg caatttcgta
      181 cgcgttttgt gcatcttgta ggttgctatt acataattgg ttgggttaga ttgagttttg
      241 ggattcggta caaatgaatc gtcaaatgac tcaagcacag gatcggaaac gtccctgcct
      301 gtgcattaca tattagatca ctctttgagt ggtcttttta ttttaaaaaa gagaggattt
      361 tgaaaaatgg aattgattgt atttactaat aacggacaaa catatcattt ttatgaagtg
      421 gagaatttta agccaacaac aacaggattt agttttattt atactgggaa ggctacggga
      481 gttactcgtt cagctacgtt taacaataca tcaacagctg gttatgcgct tgcggaggta
      541 caaaatgaat catgagaagt ttatcgaaaa atgcaaggct attgtacgtg aaagaattga
      601 aaatgagatt gctgacctaa gtggagcagt gcctgagttt agtattttca tagtctggtc
      661 atgcaaaaca ctgcaaaata gcaaagcatt agtcagcgct agcttaaaag gagcaccgta
      721 ttttgaaatt acgttgaacg gggacaaagg tgaaatctat gtagatactt atctcaaaaa
      781 atcaaatgaa tgtatcaaag tctagcaggt gctaggcttt ttctttacat aaaggaggct
      841 gcataatgag aaactactgg tatgtatcac taactaatga atatcctcga accattggtg
      901 attgttcagt gcgtgttgtg cgttctgtac aaatcaaagg gaagtactct attgtcgaaa
      961 tgctaagaga agctacacca aacgaagtgg ataaatgcaa gctgatatat tgcggtcatg
     1021 gctattggaa agacgagtat atccaataca acattgagag gtacatcaaa tgaatgataa
     1081 ctatgattac atcaagttgt tagcaagtaa ttattagatg tttttaggag gaaaactatg
     1141 aaattaaaag attatatcag agaagggtat aacgttgtaa ctgcacccaa tctagcttac
     1201 aaaattcaag aagattatcc caatgcttta gtgtttactg atagagcttt agatgccatt
     1261 cctataggga agttattagt agatcgtttt tatagcaata atccagctgt tcttagtgct
     1321 aagccacttc aaaacgctta tgctattgaa cgctttactt gcgagtttac tggatatgag
     1381 acggtagtac caatgacagg tgagacagga agaaaagtaa ttcaacagat caaaaagagg
     1441 attgctgaat tgacgttaga tgatggaagt aatacgaacc ttctagaaat caaactaaga
     1501 gatactgact cagtaccaga agtttattat aaaggtcaac gaatggatga gatgccgata
     1561 ggtcttgtcg atattactta tcattgggat acggaagaat atgaatgcca agtaccaaaa
     1621 ggagctaacg acatcactat tgaatattat gattcacata ataacaagta cttagataga
     1681 aaaatcattg ggcacaagag agatatgtaa atgattgatg tttcaagtaa acaagcaaga
     1741 gctaggttct atggatcaac tgagtggagg aaacttagaa gtcaatgctt agagcgagat
     1801 cattatgagt gccaatggtg taaagcagag ggtagactaa caactcaaca tgattcaatt
     1861 cttgaagtgg atcatataaa ggagctggag tatcatccgg atttagctct agatataaac
     1921 aacctaagaa ccttatgcaa agattgccat aacaaaaggc acaaccgtat gaaatatcgt
     1981 ggccaacaaa agaaaagaaa gtgggatgat gaatggtggt aagaaaaaca gcaaacagag
     2041 atgatgtcaa acgagcagaa gcaatcgcta tggttgataa ggctattgat aagttggttc
     2101 tatttaagag tcagctcatt gaaggaacaa caactgtaga ggatatatct atcaacaata
     2161 gactaatagg taacgctaat gaagtaacag ggacatttaa tattaatgta gacattgatt
     2221 ataccttgag tccatttgca catattgtag aaagcaacga gcaagacggc tgataaatca
     2281 gtataaagcg aagatatata gagtgaaata cccccggtca aaagattttg agaagaaata
     2341 aaatttttgg gaaccggtgg atggggtcaa ctctgcaaat aaatgatgct attttcacac
     2401 gaccccctcc ccacgtagaa aggaagtgag ttgatggctg atctgcaaga gagaaatagg
     2461 cttgtttctg ctgaagaaag gcgtctaaat aaattgttta aggatattga taaggataaa
     2521 aagaaggtcg tttctggttt gattacgcaa gcggcacgct taaaaattct tcttgatgaa
     2581 atgtggattg atatttccga aaaaggtgat tatgagcttt tctctcagtc agaaaatcaa
     2641 aaaccttacg agcgggaacg accagttgct aaacagtata attcgagaga ccaagcatat
     2701 caacgtgtaa ttaagcaact tactgactat ttgccagaag aaaagcgcga acctacaaaa
     2761 aatgcagcgc tagatggtag tgatttgctg tgacaacatt aaagccattc tattttgatg
     2821 aatacgtaga tttatacgaa aaaggggtaa tcccttttaa taaagaaaga attcagttaa
     2881 ttacttattt aaaaaacgaa gtgctagttc gggatgatat ctattttgat gaagaaatga
     2941 ttcaaaagtt tatcaagtac actgaaaaaa atttttttcc tttagctaaa tatcaaaaat
     3001 ttatcacacc tttcattttc tgctatcaaa aagaggacga cgaggtgttt tttgatgaaa
     3061 ttctaaatag tattgcgcga ggcggcggga aaaatgggtt catgtcagca agagactcat
     3121 tttttattag ccctctctac ggtgtcagaa attatgatgt aacgattaca gcgaattctg
     3181 agaagcaggg aaaggtatct tttaaagaag tttatgaaat ggtacaaatg cgcaaactgg
     3241 aaaaacaatt ttatttgact aagatggcta tagtcaacaa tgtaactaat tcgattttta
     3301 gttataggac aaacaatcct aagactatgg atagtgcaag agatggctgc ttagaatttg
     3361 atgaaatcca tcagtttgaa tcttcagacc tagttgatat tcagcgtagt gggctaggga
     3421 aaataaaaca tcctcgaact ttttataatg gtacaaatgg tcatgttaga gaaggttttt
     3481 atgacaaaat gttggaacga gcacaaaaga tttttagtgg agagaacaag aatgatcgct
     3541 tgtttccctt tatttgtaaa ctggataaca ttgatgaaat ggataatcct aaaatgtggt
     3601 caaaggctaa tccaatgttc gaagaagatt cagcatattc aaaacgtctg ttttctacag
     3661 tgatgaaaga atataaaaaa ctagaagatg agccatcagg taggcgtgaa tttgttgtta
     3721 aacgaatgaa ttttacagaa ggtgatgcag aatcagatat tacgactcat gaaaaattaa
     3781 tggctactaa acaagaattg ccaaatttga atggtcgttc ttgtgtggct ggatttgatt
     3841 atgcaagtat tcgtgatttt gcaacagtgg gtttgctttt taaaattgat gataaattta
     3901 tctggcagca acatagtttt gctaggaaaa agtttctaga tacattcaaa ctgaaagcgc
     3961 ctattaagga ttgggagaaa aaaggtttag tgacaatcgt tgatgagcca tcaattgatc
     4021 ctcgtcattt aattgattgg ttaaatgaaa aaagaaaaat ccatcaaata gaaatcgttt
     4081 gtgccgacgg atttcgtatg gatttgctga aacctcttct agagaaagaa tcatataatt
     4141 ttgagtttat cagaaatata agaggtgtgc agtcaaaagt tgctcctatt attgaagatg
     4201 gttttgcaaa tgaacggttt atttttggtg atgatcctat gatgcgttgg tatacaaata
     4261 attcgtttat caaagaagac aaattaggga ataaaacatt tttgaaaaaa gagccagtaa
     4321 ggcgtaaaac agatgggttt catgcttttt tggcagcttt atataaacga gaagaaataa
     4381 ctgatatgga ttatgaggaa gcatttgata tgttggatga gattgaattt taaggtatac
     4441 tccttattga aaggggtagt tatagaagtg aaaaagagat attttctatt tgttacaata
     4501 tttataataa tagcaatttg tgttttgaca gtatttttac cacaaattac tgagtattta
     4561 aattatcgga tatttaccac aaaagtagat gatagcgtta ctagtttaag taggctagaa
     4621 tttataaaaa tatgtgcatc tgtgtttggt cctattttga ctgtaatggt atttgtgaat
     4681 actttaaata tgcagaaaaa aacagagcaa aagcaaaatg agcttgaagt aaagcaagct
     4741 aaggctgaga acgagagagc aaaaaaagag ctgttaacac agatagatcg tgagttctat
     4801 tttttattaa atatgtttat tgaaatacaa aaagatcaaa atgccaaaca agctgttatt
     4861 gctttacaga agttggcaat ttttaacgaa aagggtttta atcaagacta tgcatttact
     4921 tctaaagatt tatcagatag tgaaattggg agtacaattg aacaatcagg accgctgaag
     4981 ggcacagttg aatatataaa atttgaaaca tttgatgtaa gcaagtcgat ggggaattat
     5041 caaacaaaaa caaaagacgt tgctacaagt ttacacgatc agaaagtagc tatattgaat
     5101 gaacaatatg aaaagatgca aatatatctt ggacggtact tcaaaatgtt tcaccgaata
     5161 gttaaaacat taaatgagta ttatgacgat tataatgatt ttgatgtgaa gaggtataca
     5221 aaatatatag ggacattaag aacacaaatt tctccagctg aattccaagt gattttattc
     5281 aattctctat atataaaacg aggttttggc ttaggaattc aacttattgg aagtggtttt
     5341 tttggagatg attttgattt tgaaactaat caacattttg aaacaagtat caatgaacag
     5401 tggtttctat cactatcaac tgttgacagt gataactcta taaagcgaca aaaattatct
     5461 gaatatatta aagaattagg atccgtagaa tataaaaaaa tagctaattt tgaaagttta
     5521 tataaactct ttaatgaaac taagctctag aaatagggct tttttatttt tctttgaaag
     5581 gtggtgaaaa catgtgagct tatttgatat ctttaagcag tcaataagaa atgaagagcc
     5641 ttctgagtgg ataccggatt ttgtatatgg agaggaagta tctgctcggg catacctcaa
     5701 aattatggca aaaaatactg ttttagattt tgttgcaaga actatgtcaa cgttagaagt
     5761 taagtttaaa aataaagatg ggacatcaga ctgggattat attctaaatg ttcgacctaa
     5821 ttctgatatg tcagcagcta cattttggca aaaatttttt tatcggctct tagatgacaa
     5881 cgaagtgtta gtaatattta cagatgataa tcaattgctg attgctgatg attttagtcg
     5941 aacggagtat gccgtgtatg atgatgtttt tacaaatgtg atggtaaaaa attttgtctt
     6001 tgaacgttca tggaacatgt ctgacgtcat ttatatggaa tataataacg aagaattaga
     6061 aaggtttaca cgaggtttat ttgaagatta cgccgcgttg ttcggacgga ttctagaagt
     6121 tgcaatgcgt aacaaccaaa ttcgtgggtc tgtatccatt gattcaacgg gaacggcgaa
     6181 tgatgaaaaa ggaaaagatg gtaagactag atctcaaaga ttacaagaat atattgatag
     6241 gatttggaac tcttttaaaa ctaactcagt tgcaattgtt cccaaagtga aaggctttga
     6301 gtatgaggaa tacaccaata aacaaggcgt atcgaatcaa tcgctagatg aactgaataa
     6361 gatgaagtcg tctttaattg atgatgttgc caacgccata ggagtaccta cggcgcttat
     6421 ttatggtgaa aaagctgaac tggattcaaa tattaaagct tttcgtaaat tgtgtattgc
     6481 tccactagtt aaaaaacttc aagacgaatt ggtggcaaaa ataattagtc gtcaagagta
     6541 caaaaacggg gaacgtatag aagttaaaaa agttctccaa aaagatctat tagagtatgc
     6601 tactcaaatt gataaaataa catctggtgg tgcgttttat attgacgaag ttcgtgatga
     6661 agttgattat gatgagttgc caaataatga aggaaaaatt cgtattcgta cgaaaaacta
     6721 tgaagaaact gtgaagggag gtgagaacga caatgccgaa agctaaaaaa gtaccatttc
     6781 agtttactaa cgaaattcag aatggtaagc acattctcac cttgagtgga aatgtacaga
     6841 aaaaatattg gcgtgatgat gatgtcataa acgctaaaga tattcgtgac tctctagata
     6901 ctgtaaccga tgatattgta atcaagttga acagcccagg cggtgatgtg tttgaaggga
     6961 ttgagattta caattattta aaagatcacc catcaaatat tactgtagaa gttacagggc
     7021 ttgccgcaag cgcagcaacg tttattgtcg ctggtgccaa tgatgtgatt atgaatgttg
     7081 ggacttcttt gatgattcat gaagcttcta catttgcttg ggggaataaa caggacatcc
     7141 aaaaaacgtt aaacgcattg gaaacgatcg atgattctat cttagctatt tattcagata
     7201 agactggcca atctgttgat aagttgcgtg aatggatgaa tgaagaaaaa tggtttacag
     7261 cagatgaagc tgtcaaatat ggatttgcca attctgtgaa gcgtgaagaa ccacaaaatg
     7321 aacctcaaaa tattgcagcg atgattcaag atgctgttgc cgttgcaata gcgaatttaa
     7381 aggaacctgt tactaataaa atcgaacaag aatcaaaaca aaaatcatta atcgcacgat
     7441 tgcgaaaagg agaataaaga tatgttaaaa attacagata aaactgcaga tgcaaaaaag
     7501 gcatttaatg ctatttcttc gaaagaagat gcaacacccg aacaaattaa tgctgctcta
     7561 gaagaatatg taaccgccat tgcagaagat gccggcaaac aggtgcgtgc tgaatatgaa
     7621 gaattgaaaa atgtgacgga caaccgtgta ttagaggctc gtggaattcc tacactaaca
     7681 gcagaagaaa caaagtttta taatgaagcc gtaaaatctg gaggtttcga ttctgacgta
     7741 gtttggccag aaacgatttt ggaacgtgtt tttgaaaatc ttcaaaacga tcatcctatt
     7801 ttaggcctca ttaactttac accaactgta ggtcgtgtca aagtaattag agcacgtcgt
     7861 aaaggtgttg ctgtttttgg accattgcat aaagaccttg aaggccaact agatgctgaa
     7921 tttggtgcaa ctgaatttgt tcaacttgcg ttgaccgcat ttttcttaat ttctaatgat
     7981 accttagatt taggaccacg atggattgac cgttttatca atctttcttt aagtgaagca
     8041 gtacgtgatg tttgggctaa aaaaattatt acaggttctg gtaaagatga gccaattgga
     8101 ttgcttaaag atctagatgg tgcggtcaca agtggtgtat atccagataa agctagcgca
     8161 gggacattaa cttttgcgaa agagaagatt gttcttgaac ttgcaggggt gatgaaaaaa
     8221 ttatctaaat acacatacaa agtagatggt gacgatgaag gtgaagtgaa ataccgttct
     8281 gttgctggac gagtgtatct aattgttaat cctgttgatt actgggatat cgtagctaga
     8341 gttacatttg caaatttaaa caatgtgtat gggactacga tgccatttat cgctgttgat
     8401 catatcatcg aatctgtaga cgtaccagaa agtaaatgta ttgcatacgt tgataaagag
     8461 tatgaagcta ctcaatcaag agctgaaaaa gtctatgtat ataaagaaac ttttgcaatg
     8521 aaacgcgcaa ctttgtatgc tgtcgacatg cttggtaatg gctatccaac aaataatgat
     8581 gcagcacaag tatatgactt ggactttaca gcgggggagt aatgtcccct gcaattggtg
     8641 agataacacc gacgactgat ggggcagtca ttaatctttc gtaaatgggg ttagagtatg
     8701 aacactgaag aatttataaa agaatataag gcccgatttc gtattttcca tacttccgaa
     8761 gatgaggata tcgggaaaca gttagagagc gggtttgccg atataaaatc tctaatcggc
     8821 agttttgatc cttccactta tgagaaagga aaagaattag tttatgaacg tactcggtat
     8881 ctacggaacg aatcactaga gtacttttac gacaattttc aaacaatgat tatggatgca
     8941 tcaattgatc tggcaggtgc tggatatgcc aattaaatca aattataaga agcctaaaat
     9001 tgtagctggt gatctaaata cgccagttac tttttttgag tttcaaccta ataagggtcc
     9061 agaacctggt gatgaagaaa aaaaggaact gtatttttgt acagcactag tttacaaccc
     9121 atcaatgaaa gatcgtgaca ttcttggcac aaaagaaggc gttacgataa aaatacggga
     9181 tccccatcaa tcttatattc ctactaacaa acataaagta aggatattag attatcgata
     9241 tggagataaa gtttgggaaa taatcgatgt ctcaccggat ttggaagaaa attcaattgt
     9301 aaagatagta ttagaattaa ttacttaaat ttggtgataa atgatgagta acgtaaagtt
     9361 tgaaggcgtt caagaaacaa tccaagcttt agaaaaaaag tatggagaaa agaaaactaa
     9421 gacattaaca aaaaaagcaa tcaatgttgg cgctgaaaaa gtagaaaaac agttgcaaac
     9481 ggacatgacc gtttttaaag acaaaggtta tacgatcgct gaggttgttc gcaagaacgc
     9541 tacgtataga gattacaagg cagaagctga aatcggttgg aatggtccac atcaacgata
     9601 tagaatcatt catttgaatg aatggggata tacacgaaag ggcaaacaaa ttagaccgag
     9661 aggatttggt gtaataacaa aatctcttaa gaattccgag ctgttgtact ttgatgctgt
     9721 aggagaggag gttaaaaaga gtttatgaaa gatatgctta atatcattta cgaggctctt
     9781 tgtttgaatg agtatattca ttcaatgacc tacaacgaga ataccgagca atatcgtatt
     9841 aaattttatg agcaacctga aaccgccgat aaaacaggtc caatgatcac aattcgtcct
     9901 gtagatacac ctaacgaagc gtaccacgga agtaacaaag agctttctgt ggagcatatg
     9961 atacagattg acgttgaatc gaaatataga gcaacatgca agcagattca atatgagata
    10021 aaaaaagaga tgaaaaaact aggctttggc caaatttccg gtcaagggtt agatgaatac
    10081 tttactgaaa caaaccgctt tgtagacgcg cgtcgttacg aaggaaatac aaaaatttac
    10141 gataccgaat attagaaatt aagacacgaa aataacgtgt ctttttttat tacccaaaat
    10201 taggaggaaa attttatgac tttagtagga ttcaaaaaaa tgacaatcgg ggtctttgac
    10261 agcacaggga agattccagc agcaaattta tatgtaattg aaggtgaaca aaacaaaggg
    10321 gcgactgtat ctgctgaaat cagtgggcta tcaaaagaac catcaaaagt ttacggatcg
    10381 aacatcgctt actatgtctc tcaaaaagga acaggcgatg tttcagctac ttttggattg
    10441 ttagatttac caacagaagt aaatgacaaa attcttggtt acaaaaccga tacaaacaaa
    10501 atcagcttct tgggagaaga tactgagcca ccatattgtg caattttgat ggaatcggag
    10561 gatttgaacg gcgatacagc aatgcttgcg atgttcaaag gaaaattcag tcgtgaatct
    10621 attaatctta acactacgac aaatgaagct ttcgaaccag aagcagaaga atatgtattt
    10681 tcagcgattg ccaatgatgt tgaaggtgat gctaaaggcc aaacagtcgc aaaatatgtt
    10741 ggagacgaag aagcttctat tactggtttg aaagagatgg tatttcctgc agcgggggag
    10801 taactagccc cgttgttgga gcaatcactc ccactattaa tggggcaaca gttgaattaa
    10861 gttaggagga taactatgcc agatacattt aaaatctata aaaaaaatgg tactgaattt
    10921 acaaaagtcg cagagggtga aagtccactt tctattactg gaattgcagc aaatactcaa
    10981 gttgctaaag gagattatca agctacgcgt gtggtcggag gtcaagaatc agtaaaagta
    11041 gatattcctg cattcaccac tcttccaatt tcagttactg gtgtgacgtt ggataaaacg
    11101 acagctgaag ttgaacaagg cggaacctta aaattaactc ctactgtaac accagcaaat
    11161 gcaacagaca aaacaggaag ctggagcagt tcgaatacag ctgtagctac ggttactgga
    11221 ggcaacgtta cagtaaaaac agacgctgaa gttggcggaa ctacagaagt ttcatttact
    11281 actacggatg gcggtaaagt agcaaaatgt actattacag ttattgaaaa agcagcgggc
    11341 tagtcttcgg actagctttt ttatttggaa aataatggag gaatctaaat ggcaaaagta
    11401 agaattgaat tgaaagaaga atcaggaaag aaagtctatg aaaacataga cacaacaggg
    11461 aaagattatc gaaaagcttt agaaacaatc aaaaagctaa atgaagacgg agtaatgatt
    11521 tggaatcgtt tagacattta tttggatttt gctgtaggta tcttcaggga tagcaaattg
    11581 acagctgaac aaattcttga tggcttacca tctgagaagg taatgagcac attggacgac
    11641 atcctaggag aagtaatggg gattgaaagt aatccagacc cagacgcaaa aaagtaacac
    11701 ccgaagaagc agaagaaatg tacttaaacc tatgcagaga gttagtgaaa gcgggatggt
    11761 cactatctga catagaagat aattcctttg aaatgatgat gaaaattgcg tgcacttcgc
    11821 ctaagaaaga gaaacaaaaa gaagttgatc ttaaagactt cttgaaatcc atgtagagag
    11881 gaggtaaaca tatggcaaat ggaaaacctt taggcaatat gattatcaaa ctagacttag
    11941 acagttcagc tttttcaaaa ggtctagccg gagctaaaaa cgctgttaac catcaaatga
    12001 aagcaatgaa atcacagatg caagtaatga actcttcagg aaattctctc ggtgctttac
    12061 aagcaaaata caatggttta ggcggagttc tacaagcaaa tgaaaagcaa gtagaattgc
    12121 tcactaaggc ttataaggat agttttgact ctaacggaaa cgctactgct tcgactgcta
    12181 aatacgctaa tcaattgaat caagcaacag ctagatcagc aagttacgaa tctcagatga
    12241 aaacaactgt tggacagatt gctcggatga aagtggaaac ggaagggttt acggggaaac
    12301 taaaggctaa ttctgatgta ttgattaatt ctgggaaaaa aattgaagcc tttggtaaag
    12361 gagtttctgg gataggatct gccctaactg ttggagtaac agctccaata gtggcaggcg
    12421 caactgctgt tactagtgca gctatttcat gggaaagtgc ttttgcaggt gtaaaaaaga
    12481 caaatgatga agttgtagac tcgaatggaa acgtagttta ttcctatagc gacttagaga
    12541 aaggtctgcg taatcttgcc acccaattac ctggtagcca tcaagaaata gcaaatgtag
    12601 ccgaagcagc cgggcaatta ggtataaaga ctgaaaacgt agttagcttc actaaaacga
    12661 tgatagacat gggtgaatcg actaatatgt cggctgaaac tgcggcaact tctttagcac
    12721 gatttgctaa tattacccaa atgtctcaaa aagactttga taaattagga tcagtcattg
    12781 ttgatctagg taacaatttt gctacaaccg aatcagaaat cactgaaatg ggattgcggt
    12841 tagcgggagc tggtaaacag attggaatga gccaaggcga aattctagga tttgctactg
    12901 ctctatcttc tgttggtgtc gaagctgaag cgggtgggtc tgccttttcg aaggtcatga
    12961 tccagatgca actagctgta gaaaaaggat ttggcgcttt tgatcagctg aaacagatgg
    13021 cagaagaaca aggtgttccg tgggttaatt tagtaaatgc tgtgagagac ggtggaaaat
    13081 cgttaaaagc agtatcagag caaatgggat tcacttcatc tgatttaaag aaaatgtata
    13141 aagaagcgga caattcgaaa agttcgcttg aaaattttgc gaatgtggca ggtgttacaa
    13201 gtgaacaatt ccagaagttg ttcaagagtg atccttcaga agcaatcatc aagttcattc
    13261 aagggctgaa agattcagaa aaacatggta cttcagcaat caaagttctg gatgacatgg
    13321 atataaaaga agttcgacta cgcgacagtt tattgagagc tgcaaatgct agtgacatat
    13381 tcaaaggagc aattgaaaaa ggaaacggcg cgtggaaaca aaatacagct ttaacaaatg
    13441 aagctaataa aagatacgaa acaactgaat caaagctaaa gatattgaaa aacgaagtga
    13501 ttgatacagc aatcgatctt ggaggtccat ttgtagacgc gttgcgtgat ggtctaaatg
    13561 tatcgaaacc attgataaaa aacttaggga atatggcgaa agctttctca gctatgagtg
    13621 atgatcaaca aagaaacatt atcaaatggg ttggattagc agcagcagct ggtccagcgc
    13681 tgaagctttt aggaactggt acttcagtaa taggtaaagt tacttcaact actggaagat
    13741 tgacgaaaag ccttgttgat ttagcagcga aagcagcaga aaagaaggct atggatgcct
    13801 ttgcatcgtc ggtaacaaca gctggtgctg cagctgcaaa gacagcagga gctggaggta
    13861 ttggcgggtt agtccctatg atgggaaaaa cagctagtgc tgcaagtact gctgcgggcg
    13921 ccagcggaat aggcgcaatg acaacgtcac taggtttgtt aggtcctgct ctacttggta
    13981 ttgttggcgt tggtggcgca ctggcagttg gctatggagc atggaaatta tttggtgaag
    14041 aagcttggaa ttcctcgcaa agagtaaagc aatggggaac agatgtcggt gaggagatag
    14101 atagtactct tgacggagta cagaagaata ttgaaggtgc aaatggtcaa ttcggtcttc
    14161 tcaaagaggg ttttactgtt gatgatgcaa ataatatggc ggctaatttc gcaaccgctg
    14221 gaacatcttt ggaaacatct ttaacgggta gaataaaggc attagacgat gcactaaaag
    14281 ggctacctca atcagttcag gatgccatga aagaagtagc tgaatcagaa gaagaaacct
    14341 tagggcaatc tctttctaaa ataaaagaca acaatgaaga aataaaaaaa atcagagaaa
    14401 gagccgcaaa tcagaacaga gacttgactg tttcagaact acaacagata caggatctaa
    14461 tgaaaggaac ttctcaagcg tatgtggata cgctcgatgt ttctgctaaa gacagaaaaa
    14521 agatactatc agccatgaat ggtgatgttg cacaagctac agaagaagaa gcgaagacgt
    14581 ggttacaatc tttagcgaaa caaaaagctg caactaccga aaattataga caaatgcttg
    14641 aagaaaaaaa ggcggcttta aaggaaaagg gagtaagcaa agaattcatt gatgcattag
    14701 aagatgaaat gaatgattac atcaaaacta caaatcaagg attcgatagc caaatagctg
    14761 ctataacaaa taaatatcca caattgatta acgaagtgag tttatcaaat ggtcaattat
    14821 ttagcaaaac ggcagctgct atggacaata ctggtcagta tacaaaagtt tttctcgaaa
    14881 gtaatgaaaa gattttagcc caagcgaaga aaacatcgga tgaaatagca gataatgccg
    14941 aaaaaaatgc agaacaactt ggtatggtag ctgatgaggc tacgcatgct ggatcaactt
    15001 ggaatggctt agttttagac gaaaaaacag gaaaagtaaa aactaatgta caagaagtag
    15061 tgaatgaagc aacgaaggat ttcactaaat ggaatgaatt gaaacctgtt gttcatgatg
    15121 cgaaactaac aacgaatgca aaagatgtca tttccatagc ggcagtacaa aatggctatt
    15181 gggatgatat ggaatggaaa gaaaaagaag cattattaga agatgagtgt tctaaaaatg
    15241 tatacaaggc tttagaaaat gctggtaaat ggaatgagtt agatattcct tctaaagaag
    15301 caatcctaac ttcaaatact cctgaagtta tgggtgaaac tctcatgaat ttgggattat
    15361 gggatactta caaacttcaa gtgaaagatt tagatttgaa tgcgtataaa gtatacgatg
    15421 ctatcgatgg atcagaagaa aaattaaata gttgggctca attagataac cccacaaaag
    15481 aattgttatt agataactca gatttttcta caaaactttt taattccgaa gaaatgttta
    15541 aacgttggaa tcagttatca tctaatgcaa agtttctttc ggctaataat actaaattta
    15601 cagaggttct tttatcatct gacagaatgt ggaatcaatg ggtaaacctt cctgataatg
    15661 agaaaagatt acttgcagat aacgaagatt tagctaccac tgttttatct tcagaagaaa
    15721 tatacggaag atggactcaa ttaccagata atcaaaaata tatgttagct gacaatactg
    15781 acttagcaaa caaaatattc gcttcagaag aatcatggaa tgcatggaaa gcaattccag
    15841 acacagttaa aaacttgctt ggtaataata ttgatttact ggctaaagtg aaagacggga
    15901 ctgtaagtgt agaagaatat aacaaagtta tgccacttct taaaactcta tatggagata
    15961 acgttaattt aaaagaggca atcagtgggg ctaaaagctc tatagagaat tacaacaaaa
    16021 atatttttcc tagtgataaa actgcagtag gacacgatga ggcttcacaa gctgctaaag
    16081 atgcatttga agcgttcaac atcttccaaa caaaaatacc agataaaatt actaaaactg
    16141 tatcagctga ctttataggt cctatgccga aaaatgcgaa aggaacaaac ttccatcctg
    16201 gcggagcagc tatggtaaac gatcaaaaag ggcctactta tgaagagctt ataaccttgc
    16261 caagcggaga aacttttata cctaaaggac gtaatgtcgt tttagactta ccaagaggtt
    16321 cgaaagtact gaacgccact aaaactaaac gtctagtgcc taaatatgct gatggtatag
    16381 gaaacataac gacggtttca tctacgctaa acttagatgc tttaatttta gctattaacg
    16441 agctaacgac ggtattgaga actcaactga tggcaggaac gactgatgct aaagatacta
    16501 aactatcaga tgaaacaaaa gttgccgatc cgattattcc ggacagtctt tctgaaaaat
    16561 cagatcagta tctaggaatt ggagctcaat ggttaactaa tctaatgaat ggttggaact
    16621 cagcggttcc tcaatatatg aatagtgaaa tggtttttat tacaaactat ctcaatgcgc
    16681 taaaacttca aaacaatcct aattatacgc aaggagcaac atggaataag aacttactga
    16741 atggatggaa tagtttaact gggaccttta ttgctacaat caattcattt tgtaatcaag
    16801 caatggtcac gcttagaaac tacaacactc ctatgtacaa caatggccga acgtggcagc
    16861 aaaataatct taatggttgg aattcattgt atggatcatt catagcccgt gtaaatcagc
    16921 ttggtaacga ttcgattaac aaccttcgtt ctaaaagtgg tggtttttac aatgcaggga
    16981 cattcttgtt gcaatcttta ataaacggaa tgaattcgtt aggtaattct ctttctacta
    17041 caatgaacaa tgtcgctaat acaatggttg gtggtatagg caaaggagtt aatggcgtca
    17101 tatcgggagt taactatgtg cttaaggaag tcgaatcaag taagaatatc ggaaactggc
    17161 caattccaca atacgctaag ggaactgatg gacatcctgg tggacttgct atgattaatg
    17221 atcaaaaagg cctagttcac gaagaatatg ttcagatgcc agatggacgt agttttattg
    17281 ccaaaggtag agatcttctt gttaatttgc ctaaaggtgc tcaggtctta aatgcttctt
    17341 taacaaagaa attaaaggaa cgtttaaata ttccacacta cgaaaaaggt attggcaatt
    17401 tagatattgt tgatttgtta gatgatgaaa aaagaatgtt agaattctta actagcaaag
    17461 ttgatttttc aggcattaat gaaccatggc ttgatatgac taaatcagga acgtcattaa
    17521 tgtccaaagc tgcaaataca atgcttcaat caaaattaag tgaattcttc actcatggca
    17581 attttgatgg tgcagtaaat gccaatggtg tttatcaata tttagttgat gtggcacaga
    17641 aagtaatggg taagttcccc ggacttacag taacttctgg atatcgagca ggagatgcct
    17701 actatcacgg aaaacggcaa gctatcgact tggcttatcc aggtatttct ggagatccga
    17761 gatatacagc agcagcaaat tacgcttttg aaaaattccc ttcaaaaatt gcgtatgtca
    17821 ttacgaatgg acgtgtacgt gaccgcatgg gattatctgg aacaaggtca agcggacaat
    17881 ggacgaattg gccagatggc gatcacttcg atcatattca tttaaacggt tcgatggggt
    17941 ctggcgatat attcaatgga ggagttggag gaagtggtgt tgcacgctgg cgttcttatg
    18001 tgtctaaagc attgaaaatg aatggattac cagctacagc agcgtatata aatgcctgga
    18061 tgtcccaaat ccaaacggaa tctggtggta atgagaaagc aatcggcggc aatgatgggc
    18121 tcgccgaagg caatgcaaca ggattacttc aaacgaaacc cggaactttt gcagctaacg
    18181 cttttcctgg tcacggaaat attatgaacg gatttgataa catgttagca gcaatcaatt
    18241 atgctaagaa acgttacgga gttgcaggta tgttgcaagt tatcgggaaa ggacatggat
    18301 atgccaatgg cggcttgatt accaaagacg gactatatcg agcaggagaa ggaaataaac
    18361 cagaaatggt tattccattg acaagaaaaa caagagctat cgaacttatg ggtcaagcat
    18421 tagccttcct ttctggaagc aataaaaaag aaacgaaaag tgagattaat tctgtagata
    18481 atagacatat cctacaagcg atagaaaaac agtctcgtat gacaaatgat ctgctatcat
    18541 tattactctc gttttttaaa agtaacaatc gatcagataa agaactagct ttagatattc
    18601 agaaaatttt aatcaggagg acatagtatt tgaggacagt aatattaaga aataaattga
    18661 atgaagaaat tgatttgtcc acagaagatt attttgctac tgaaatgtcg aatctaggtt
    18721 ttgaagttac aaaagagcat attggacaat gggggagttt cagagaaata ggagagagta
    18781 ttgaattgtc tgaatttcaa tcatcagtta tgatttctgt tcacggattt agagaacaac
    18841 aattatatgg ttcattagtt gaatttctgg ctaatggacc ttttgaacta gaattttctt
    18901 ttgattcaga aacaatgatc aggaaatgta gtttgaaatc attatctaaa acagaaattg
    18961 attcccaaag ctcattgcta acagatactt tgaatctata ttttacttca agctggtatt
    19021 ctattaagcg tgaaaaatta atacagaatt caacttctct caatacacgt ggaaaagttt
    19081 actcatttgt tcgaccatat gtctacacca aaaatgtatg ggaaaagaaa ggtgtattta
    19141 agttcagtaa taattctgta tatttgacaa atagtacaga gcgaatgtct ccgttaaaaa
    19201 taaggattat tggagagtgc tcaaatccat attgggaagt tatccaaaac tctaaagtag
    19261 tagcttcaga tggctatttt attaatatga aagacacaca aatattagaa gtgtctagtt
    19321 tgctagaaga ccaaacggca attttaaaag atgtaggtgg agttgaatct tctgtttatc
    19381 aacaacaaga ttttactaaa tcaaacttcg tccaagcgcc tctaggagaa ttcagcgttg
    19441 tttttcatgt tggacatgca aatgtagaga ttgaacttta tgaggagcgt gatctatttt
    19501 gattttagcc attaccctct ttcaccgaga tatgaattta tataacgaac gtttaatttc
    19561 gactgagttc gaatttggaa cggatgaaat tggagaagaa gtaagtaatt ttattacaga
    19621 taaatatgtc catgtaaaat caggagattt tctactagca aaatttattc ctagcgggaa
    19681 gattgcttat tttggagtga ttagctcgca agaagacaaa aaaataaatt gcaaaggatt
    19741 actcagtttg gccgatagcg agataccgac tgtaaaaata tcaggtgcta attatgaaga
    19801 gcatattcga cgactgattg aatactactt attgaacgat ccaacaaaac aactaaaaaa
    19861 tattttggag gtaaaaacag aaagcgttac ttctcattct tatcaagctg ttgacacaaa
    19921 taagagacga ttgaatgcat atataataaa tgggttcaaa aaatataatg ttaaatggta
    19981 tgtcaaagag attaaaggta aaaaaatata tactggtatt cgagcagttg atgattcaat
    20041 ttatattaaa gataattcat ctgagtttaa tgactgggat gtttttgtgc aatctcctgg
    20101 accagggaac gagaacaaat tattgatcgt agataaagca atgaaagata tagaaaatcc
    20161 cttggtattg tctacgtggt atttagatga cgaaaataat cttacgcaag attcaacgaa
    20221 taagaacatt gcattgccta ccgttaattt agtaaatata tatgatcaaa ctcaagaaga
    20281 tagaccttct tatgaagagg tagctaaatc ggagcttaaa ggcaacgcct attcacatga
    20341 aattaaagtt aatgttgtgc taaatgctag aaatatcaat gtagaaaata tcgaaacagg
    20401 aatgttagcg actattgttt acaaagagca gacttacaaa tctgttctaa ctgcctggcg
    20461 aatatccagc agtaaaaaga atatagaatt gacatttggt aatgtccgaa gtcgttttat
    20521 ggattatttt gaagataatg ggggataaaa aatggttagc aatgtggatg gatatcaatt
    20581 tgaaaacgtg aaagtaagcg cagaaaatga tgctagactt tatcacgttt tatataatcg
    20641 gaaaaatcag gttattgatg gttacgatca gtctatgaat ttatcttcaa gcggattaac
    20701 agtaaaagtt gctgcaggag cagcgattat tcaaggtcgt atggtcgttg ttcgacaaga
    20761 agaaagtata acagttccag caaactcaag tggttatata gcattaacag tggatttgac
    20821 acaagaagtt atacctggat ctattcttcc agaatcggaa gaatatgaat ggactaataa
    20881 tcaagtcaag ctagaattta taacaaaagt tataaaaggt aatttaaaca atggtgataa
    20941 ggtctataat ttaccactat gctcagttaa ttctactgga tcaactgttt caatctcaaa
    21001 gatatcggat agttacgagc tgactctctc taaaggagaa attttgtgga gggggactgc
    21061 gttaatgcat gatactcaaa ctgtccaacc ttcaaaaaaa atttggcaga cagtttcagg
    21121 ttttttgtta gtatggctcc catacgaaaa cgggcaagca attgaggata gatatgtaac
    21181 tacgcctttt tataaggagc gtataacttt tactaatgtt ttaggagaaa ttgtttcagg
    21241 atttgatgac tatcacaaaa agtggtttag taaacgaata aactataatt cgaatactaa
    21301 tatatttaca ggtgcagcaa gcaatgcaag tggagataac gcaaatatgg tgcttaggta
    21361 tatagtttct ttttagttag gaggtatgga agagtggcaa atttagaaat taaattatct
    21421 gcaaataaga gacagcctta tctacgtcac cgtgttgttg gtagagttgg tgatgggggg
    21481 ctcacaacaa tcaatgtaca acttcttgag gaagatgaaa ttacaccttt tgtaattaat
    21541 ctaaacggta ctttgaaatt tgtgggcgaa gtttcaaacg gtaactatac cgagggagaa
    21601 ccagaaataa tcgattcgac taatgggtta attagttaca cgttcactaa gtcaaatttc
    21661 agcacgagtc atcaattcaa acaagcatat tttgaatatg tagatcctaa cggcaaaaaa
    21721 gtaacttttc agaacttcat catagacgtg ttagaacgag tagatattaa ttcggagcaa
    21781 gcgaaatact atatttcttc attggaaaaa ttacagagtg aaatgcaaac cactttcaat
    21841 cagttcatta gtgataaaca ggtccaatac gatcaaatct actcgaaata taacgaatta
    21901 gtaagattga taaatgaatc agataagcaa gtaaatgatc gtattgataa ggcaaataat
    21961 cgtattgatc aaaccaatca gcaaatcggc gatctcggca agctgaaaaa gatgtacagt
    22021 aacagcattg a
//
LOCUS       DACGDM010000036        21988 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.036, whole genome shotgun sequence.
ACCESSION   DACGDM010000036 DACGDM010000000
VERSION     DACGDM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.036"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..395
                     /locus_tag="IXR05_001500"
     CDS             <1..395
                     /locus_tag="IXR05_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260010.1"
                     /translation="ISLKDESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQE
                     YYFYKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKI
                     GVINFKNKYQIKGIKLNQKTIKKLNIGG"
     gene            398..1147
                     /locus_tag="IXR05_001501"
     CDS             398..1147
                     /locus_tag="IXR05_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4260011.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            1159..1428
                     /locus_tag="IXR05_001502"
     CDS             1159..1428
                     /locus_tag="IXR05_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260012.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            1590..1892
                     /locus_tag="IXR05_001503"
     CDS             1590..1892
                     /locus_tag="IXR05_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260013.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            1889..2050
                     /locus_tag="IXR05_001504"
     CDS             1889..2050
                     /locus_tag="IXR05_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4260014.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            2047..2352
                     /locus_tag="IXR05_001505"
     CDS             2047..2352
                     /locus_tag="IXR05_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260015.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            2352..2708
                     /locus_tag="IXR05_001506"
     CDS             2352..2708
                     /locus_tag="IXR05_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAQ4260016.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            2668..2913
                     /locus_tag="IXR05_001507"
     CDS             2668..2913
                     /locus_tag="IXR05_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260017.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            2910..3329
                     /locus_tag="IXR05_001508"
     CDS             2910..3329
                     /locus_tag="IXR05_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HAQ4260018.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            3326..3883
                     /locus_tag="IXR05_001509"
     CDS             3326..3883
                     /locus_tag="IXR05_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAQ4260019.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            3880..4176
                     /locus_tag="IXR05_001510"
     CDS             3880..4176
                     /locus_tag="IXR05_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260020.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            4253..4666
                     /locus_tag="IXR05_001511"
     CDS             4253..4666
                     /locus_tag="IXR05_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAQ4260021.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            5012..5386
                     /locus_tag="IXR05_001512"
     CDS             5012..5386
                     /locus_tag="IXR05_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260022.1"
                     /translation="MEDKMYLRQKVFTKKDIENQINGFIQKLENANSYLINKELNKAY
                     DQWKEVYDELKLIQNETKLVRTEKKNENSFFFDGYAILMLETVAKQNIKAPKKELSDN
                     IDNALAELRYYVMQIKDVRITR"
     gene            5616..5960
                     /locus_tag="IXR05_001513"
     CDS             5616..5960
                     /locus_tag="IXR05_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4260023.1"
                     /translation="MNEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            5965..6246
                     /locus_tag="IXR05_001514"
     CDS             5965..6246
                     /locus_tag="IXR05_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260024.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            6349..6663
                     /locus_tag="IXR05_001515"
     CDS             6349..6663
                     /locus_tag="IXR05_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAQ4260025.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            6641..8335
                     /locus_tag="IXR05_001516"
     CDS             6641..8335
                     /locus_tag="IXR05_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4260026.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNANLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            8355..9533
                     /locus_tag="IXR05_001517"
     CDS             8355..9533
                     /locus_tag="IXR05_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4260027.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            9496..10182
                     /locus_tag="IXR05_001518"
     CDS             9496..10182
                     /locus_tag="IXR05_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAQ4260028.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            10182..11342
                     /locus_tag="IXR05_001519"
     CDS             10182..11342
                     /locus_tag="IXR05_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4260029.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGRLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            11352..12227
                     /locus_tag="IXR05_001520"
     CDS             11352..12227
                     /locus_tag="IXR05_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260030.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWARLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            12224..12535
                     /locus_tag="IXR05_001521"
     CDS             12224..12535
                     /locus_tag="IXR05_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260031.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            12525..12878
                     /locus_tag="IXR05_001522"
     CDS             12525..12878
                     /locus_tag="IXR05_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAQ4260032.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            12868..13269
                     /locus_tag="IXR05_001523"
     CDS             12868..13269
                     /locus_tag="IXR05_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260033.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            13262..13666
                     /locus_tag="IXR05_001524"
     CDS             13262..13666
                     /locus_tag="IXR05_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260034.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            13678..14286
                     /locus_tag="IXR05_001525"
     CDS             13678..14286
                     /locus_tag="IXR05_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4260035.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            14306..14668
                     /locus_tag="IXR05_001526"
     CDS             14306..14668
                     /locus_tag="IXR05_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260036.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            14671..14853
                     /locus_tag="IXR05_001527"
     CDS             14671..14853
                     /locus_tag="IXR05_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260037.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            14870..18289
                     /locus_tag="IXR05_001528"
     CDS             14870..18289
                     /locus_tag="IXR05_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAQ4260038.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNTLAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     VTAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGESGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRTQAVQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            18340..19077
                     /locus_tag="IXR05_001529"
     CDS             18340..19077
                     /locus_tag="IXR05_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4260039.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            19087..21378
                     /locus_tag="IXR05_001530"
     CDS             19087..21378
                     /locus_tag="IXR05_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260040.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKALAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLHHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            21402..>21988
                     /locus_tag="IXR05_001531"
     CDS             21402..>21988
                     /locus_tag="IXR05_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260041.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIQKYNETFDAFMAEIEGRVDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSI"
BASE COUNT         7933 a         3246 c         4705 g         6104 t
ORIGIN      
        1 aaataagcct caaagacgaa tcgaatacaa ccgtgagtga tgccaatatc ttagcgaata
       61 tcatcctaga tttcatcttt gaacatcata ttcctttcaa agaaggatat gagattttac
      121 cagcgaatca agagtattac ttctacaaat gcattacaaa aagagtctgc tgcatctgtg
      181 gcaaaacagg agctgacatc gatcactttg acaaagcgct aggaagacga aagcgcaaag
      241 aagttgatca tgcagagtac acatttgcag cactctgcag aatccatcac acagagaagc
      301 acaaaatagg tgtgattaat ttcaaaaata aatatcaaat caaagggatc aaattaaacc
      361 agaaaacaat caaaaagtta aatattggag ggtaaaaatg acagaacatc gaagttatta
      421 tgcgattata ccagccaacg taaggtacga caaaagactt aaaccaaata ctaagttgtt
      481 atacggagag ataacggcct tgtgtaatga aagaggcttt tgttgggcag gcaatgagta
      541 ctttgcagat ttatatggtg tgaataaaga gaccatatcg cgatgggtaa gtgatttgat
      601 taagtttgga tacttgaatc gggaaatcat ttacaaagag ggtaccaatc aaataatcaa
      661 taggtaccta cgaattaatc aataccctat tgacgaaaaa cgcaataccc ctattgacga
      721 aaaagtcaaa gataataata catctattaa taatacattt aataatacaa aagaatatat
      781 aagagagtta ccgccttcga aaaaatcgaa ggctaagccc gtccgtcata aatacggaga
      841 gtataaaaat gttcttttgt cagatgagca gatggagaaa ctcaaaacag aattccctaa
      901 tgattaccaa gagcgaatcg aacgactgtc agagtattgt gaatcatctg gtaagactta
      961 taaaaactat ttggcaacta ttcgaagttg ggcaaggaaa gaaaaaagtg aacctaagaa
     1021 cgcaagcagt ggatacaagc gcacaggaag acgagagaag cttcctgaat gggcaatcga
     1081 ccaagaagcc tatctcaaga aaaaagcgct agaacgagct aatagacaat caaaagcacc
     1141 attctaagag gtggaaaaat gaagatcgat tatctagaac taattaatga aatagcgaat
     1201 tataaaaagg gcgaggaatt agacgtcctg agagacgtat atgatcaact cgaagaagct
     1261 ggaattgaag gaattaagaa tgatcgttcg agttggagta agctcagata ctatttcgca
     1321 ctttatatcg atacaacaca attaagaaat ttagcatata ccaaattact atttgttgat
     1381 tgtgttaaag gcttgcaaaa acatcttaat gaacttgagc aggtgtaatc agatggacct
     1441 aaagacattt acagcacaga ttgaactaat gcatcaagaa gctttaagac aaagtgtatc
     1501 gtacgaagac aagtggctca acacgttcca tggcggacgt gagagcgcac ttgatcaagt
     1561 actcaaatta ctgaaaggag aatgtcggga tggataagaa agcggcaatg cagcgaatta
     1621 tcgaattgac ttattcagaa gattggcaaa atgacaaaga agctgcttca gaagtgatga
     1681 ggcttggaag agcgatgtgg gcagacaaga gcaacaagcc aagaccacga aaaatcgcaa
     1741 tttggcacgg tgacaaactt ctagtgatag ggacagctga acagttagca agtctcacag
     1801 gcttgcacga gaaaatcgtg aggaaaagag caaggtgtgg ctacacagac gctaagaaga
     1861 gaacgtttag atacgtggag gaatcatcat gacaacagaa gaagtgattc aaatgcgtat
     1921 tcgaagcctt cagcgtgaga ttgacgatct ggaacgaaca aaggcagtga tggtcaatga
     1981 aacggcgaga aaggcaatcg atttgcacat agagaattta agaagggaaa tccatcgatt
     2041 ggaggaatga gcgtggataa gaaagcagca atgaaaagaa ttgctgaatt aaccaagtca
     2101 gaatcttggc aagaagacaa agaaatagtt gcagaagtcc aaaagctcgg taaatcaatg
     2161 tggactgaaa agcccaaacg gagaacgccg agaaaaattg caatctggca tgatgaccga
     2221 attttagtaa caggtactgc tgaacagtta tctgaaatta ctggattaag caaaaacatt
     2281 atctgggata gagctaggag cttatggatt gattcaaaag gacgacagtt taggtatgtg
     2341 gaggagagat aatggatctc attacacaat acagtgacat catcctcaag aaaatcatga
     2401 tgaagattca gaaagataaa aaatcaaaag aacgagctga attagttaag ttagaaatgg
     2461 ctgaaacagg agcaggagtg cgaagtagca ggcattggaa agcagcagca aacattgaat
     2521 tttattacaa cgaaattcaa aaagggttcg atcagatgcg tgagctggat cggcaaacaa
     2581 attggagcaa gaaacttcat caagatcgtt tcaaatttgt agagaagtat aaagaaatat
     2641 tagaagagta tttgaggagg acagcaaatg ataaaaaaac tcgttcaatt cagcatggat
     2701 ttatatgata tcgaatcagg agcaacacta tctgtggaat cggaccatct aatcataaat
     2761 tttggtggaa agcgccagat tattttgtgg gtagttgatg atgtactgtt tccagaaatt
     2821 gttcatgatt tcgaagaatc aaaagcggtt gagtttgaaa tagtgaaaaa agtaatggaa
     2881 ttgattgaaa aatacgagga ggacagcgaa tgataccgaa gtttagagcg tgggataaac
     2941 gaaagaacgt aatgagagat gtagccgtct tgcattttac taaaaacggc aaaacaaact
     3001 ttattgaata ttggataaat cctaccgaat tgaaatcata tcacgtgcga aacatcgacc
     3061 tcatgcaatc cacaggaatg aaagataaga atggtgtgga tatatttgaa ggggatatag
     3121 tattagtcag cgtgcgaaat ggcttcgatt acttagataa taaagtctgt attgtcaaaa
     3181 attcaataga ttattccgga ttagtttgtg ccactgttga tgaagactta gagtatcaaa
     3241 tttttaacac agagctgttt gaagaataca cgtacgaagt caccggaaat atatacgaga
     3301 atagcgagtt attggaggaa cagcgatgaa taaacaggaa gcaatcaaaa agttagaaag
     3361 tattaaagcg ataggaaatg atgcaatagc tgcttgctat aacgagagta taaattcagg
     3421 tattacgtta atgaaaaaaa tagacgaacc gcagaaacca gttattccac aactcgtggc
     3481 cggttggctt gagaaatcta cggacccttt tacaaaagct gaaaaaatag cgtatttaat
     3541 caaatctaaa gatggtgatt catattattt ctgtgattgg tttgtacgag atggcatagt
     3601 gacgcaagag caaggagaag aattactcgc ttgggcaaca agacaatcat atgaaacact
     3661 attgagccta tacaacggct acgaggttga gaaagagccg ttatgggcaa taaagaatgc
     3721 cgatggaaac tatcttacta aatgtgcttt atggggaaaa gatggagtaa attatagttt
     3781 tgaatgcaat ccatctcatc gattgctttt cactgataaa gcaacagcgg atgctgcagc
     3841 attgttggtg aatggaacag tggaagaggt ggtagaaaga tgaaactaaa agacggattt
     3901 tacgctagca gtcacggtat cggcggttta atgctagata tgccgacaaa gaaccctaaa
     3961 acacgcaaga aatcaaaatt caaagtcggt gacatggtcc gctgtgaagc agaagagttc
     4021 gtttatccgt tcagaggata cgttaaaaag atactgtcaa actcagcaat cattcgtatt
     4081 gaaaatacaa tgaagtgtga tcgttcgact gcaaaacaca agcattattt agctgtagcg
     4141 agattagttg acatggaagt aatcaagagc aaataaaaaa agccggatcg ctccgactga
     4201 ttcaataaat ccaacacatt tattatatca cataaaggag cggtttgact tgatgcaatt
     4261 gttacgagag gtagatttca aacagacaag atgtaatgcg agagatgtgc tgaagaactt
     4321 tcggcgtttg gagcggatgg caggtcgctc tttgatagat attaagtcgc cgattattac
     4381 ggatatgccg aaggcaccaa agcacggcaa taaggcagaa gacgcgatca ttcagatgat
     4441 ggatatagaa gcggagagag atgcgattct agcggctttg atggctctta gtctaattag
     4501 tcgccagata ctctactaca gcttctgtgt gccagatagc ttctcaaact acaggattag
     4561 ccgtgaagtg ggttattcag aaagaagtat acaacggatg aagtcggaag ctctaataga
     4621 gtttgcagaa gcatataaac acggaagaat aattgcttat aaataatttg gcggtttttt
     4681 ggcggaatga tggcggtttt tagctattta ccagtgatat tatggtagtg tcgaaagatt
     4741 agtgataggt ctaagacaaa ataaaatgta agggaggaaa tctccctcat cgtttaatta
     4801 agcttcgata gacagcagca aataaactaa aggatgtggg ggtcagctcc tacagttagt
     4861 tcatgtgttg ctgtctatta attgcaactc tttcggtttt attgagtatt tactcaactt
     4921 aaaaaaactg ttgtttgtag atgtaagctg ttcctatttg tacatagtaa aaaatgatat
     4981 aataaaaata ttacgaaagg ggtgagagtg catggaagac aaaatgtatt taagacaaaa
     5041 agttttcaca aaaaaagata ttgaaaatca aattaatgga tttatacaga aattagaaaa
     5101 tgcaaattct tatttgataa ataaggaact aaataaagct tatgaccagt ggaaagaagt
     5161 atatgatgag ttgaaattga ttcaaaatga aacaaaatta gtacgaacgg agaaaaagaa
     5221 tgaaaatagt ttcttttttg atggatatgc tatattgatg ttggaaactg tagcaaaaca
     5281 aaatataaaa gctcccaaaa aagaactatc tgacaatatt gataacgcat tagccgagtt
     5341 aaggtattac gttatgcaaa taaaagatgt taggatcact cgttgagtgg tctttttatt
     5401 ttgcacaaag gaggtaacaa caatgtatag accacaatac ttagaacaga agtatgaagt
     5461 aatcactgtg caaaatggta acggagagat agtacgaaag tatagaagac caataaagag
     5521 cgatacatat aaacgaaagg aaagcaatga agttattcca ttgtatggca aaagaatagc
     5581 taagcattaa ataagattgt gaaaggagac gggacatgaa cgaggaattc tatagatggc
     5641 tattacagtt gataagagaa gatcgtttgg ttaagttcta tcagtctcct aaatggcgca
     5701 ggcttagaga gaaagcgatg aaacgagatc actatgaatg ccaagagtgt agaagactag
     5761 gtaagtatca tagagtagag aacgttcatc atataaagga agtcaaggat agacctgact
     5821 tagctttaga tttagataat cttatttgtt tatgtgttga acatcataat gaagttcatg
     5881 gcagatatct tacagcattg gataaacaag agaagaagat agaaagcttt gctaacttcg
     5941 atgcaagtga aaggtggtaa gtgcatgatc atcaatgata atggcagaga gtatgataca
     6001 gaaaagattg aagagtattc atcttatact cagggattaa ttaaacgttt gatatacgtt
     6061 cgctatgtag gtattaggga tctgttatca gataactgtt gtagtaaata caaagtgaat
     6121 caagtaagag aagcgttgaa taaagataat aacgtcgaaa gaataaaaaa tgtttttgga
     6181 tatagtattg aagagattaa ttattacatt gacttcgctg aagctttcat tccgatggtg
     6241 agataacccc cccttaaaat aaatcgcaaa ttttttgggg gtgatgaaac ggagggggct
     6301 gtcaggaaaa gagatttttt cgaactttat catgaaagga gggctaaaat gtttaaaaac
     6361 gaattgtctc aaaatcgcta cagagaaaaa ttacgccgct ctttaataag ccaattggaa
     6421 agtcagaaaa caaatattga gccattctta gataatgttg atcgttatat cagtttatgg
     6481 gaaacggcga tatcactgga agaagatata tccgagaacg gcattagact ggagaatggt
     6541 aaaaagaatg aatcagtagc gttgcttgtt tctgtcaaca aacaaatggg attgatgttg
     6601 gataaacttg ccattactcc tgaattggta ggtgaagcaa atgaatcaat tcctgagtta
     6661 taagcatatt gaaaattggt tcaaagctat agaagaaggc actatcaagg tatgcaaaga
     6721 gcaattattg ctaaaaaatt atctagaaga aagagtcttt actagagaag atatttactt
     6781 cgataagcag atggtagagg attcaatcaa tataccagca caatactttc cattcgaatt
     6841 aattccgtgg gaaaaatttc tacaatgttt tatttatggt gttcgatgga aaaaagataa
     6901 aacactagtg ttcaatagat atctttcatt aatgggacgt ggtaatggta aaactggttt
     6961 tgcttcttgg aacaacttct ttctactaac cgctaaacac ggtattaaaa attatgatat
     7021 tgatatctat gccaataatg aaagccaagc aaagactagt tttgatgatg tatttaaagt
     7081 aattaaagat catcctgatt tagataaaaa agtatttaaa gctacgaagg aagttattca
     7141 aaatatcgct acaaacagca aacttcgtta taacacggca aatgctagaa caaaagatgg
     7201 gaagcgacca ggtgcaaacc gctttgatga aattcacgaa aatgaagatt attcaatgat
     7261 aaatgtggct acttctggtg gtggtaaaat tcgagattat agagaatttt atgatacaac
     7321 taatggtcat gttcgtggtg gtccgcttga tgacattata gaagaatcaa aaatgattct
     7381 ttctggagaa cttggaattg acaaggatgg agcagaattt tctagtttgt ttccatttat
     7441 ttgtcgcttg gataacgata atgaagttga tgatcccgac atgtgggaaa aagcttgtcc
     7501 aactattaat tacaatgcaa atttaaaacg gaaaatgttt caagaatact ctcaaatgca
     7561 acgtaatgct ggtttaagac ttacgttcat gaccaaacga atgaacagac ctatggaaga
     7621 tacacgattt gctgttgctt catatgatga tgttctgcat acgaaagaaa aagaatttcc
     7681 tgaaaaaatg gatgaagtga taggaacagt cgattttgct gatagacgag attttgccag
     7741 cgttgggttg ctaggaaaat acgataaaga tgtttatttt acacaacata cttttatcca
     7801 cgaatcagcc cttcgattac aaaacatcaa acgagaggtt atagatattt ctatagatca
     7861 aggaaaatca cagatcgttc atggaaaaaa tatagaagct gattatattg taggttggtt
     7921 tcttgaaatg agtaataaat attatattaa aaaaatcgct atggatatgt accgtgcaaa
     7981 aatattgaag cccgctttag aagaagcagg ttttactgtg gaaattgttc gaagcggatc
     8041 tgttacacat ggtatgttaa aagatctggt tgatgacctt tttattaatc aacgtttatt
     8101 ttttggtgac gatgcgatta tgcgttggta ttgcatgaat gtatatgaag agcatatttc
     8161 taatggaaat atacgctatg aaaaaataga acctgaaact agaaaaacgg atggcttttt
     8221 ttcattcctt catggtttga attttttaga tgatatttat gattctgctc ctgtaacagt
     8281 cacaaatagc tcagtagaaa atacaggaac tggatttact cctctagtat tctaacttga
     8341 aaggaggtga gaaagtgggg atttttcaaa aggcggtagg atacttcaca aaaaaagcaa
     8401 cggttccttt agaagaatac ttttgtaaat tgcaagttga ttttgtgtat cgaaaatttg
     8461 cgattgaaac ttgtattgat ttgattgcaa atgcgatgag taaagcggaa ttcaagtcat
     8521 atgaagatgg aaaaaataaa aagaatgatc tttactatag gctgaatgta gctcctaata
     8581 agaaaaataa tgcaacagaa tttagaaaaa aactgatcag gagattaata ttctacaatg
     8641 aagtattgat cgtttctccg tctaataatt ctagcgaaat atttattgcg gatagttggg
     8701 atgtcacaga atatgcattg aaagatgatg tgttttctca agtgcaaatt aacaacatag
     8761 tccttgatag agaatttcta gaaagtgatg ttatctatat aaaatacgca gatcaacaaa
     8821 ttaggcaact agtcgatgcg tattatcaag cgtatgggaa actcatttct agtgccatga
     8881 atgtttacaa gcgctctaac gctcgtagat acgtactgaa agggaattta ttccgaccgc
     8941 aagacaatac aacacaagat caaatcaata aaatgatgac atcacaattt aaggctttta
     9001 tggaagctga taatgcaggt gcggtatttc aattacaaaa tgagtacaca ttagaagatt
     9061 tcagcggaaa cttccaaagc aattcaagag atataaaaaa cttaatagac gacatctttg
     9121 agatgacagc agcagcgttt cacgttccga aaaacctact aaagggagac atgagtgggt
     9181 tatcggatca agtggacgct tttttaatgt tcgaaatcat accgattgct gaacttattc
     9241 aggatgcgtt taacgctagt ctctatgaag tagaagaata cttgtcaggg aattttgtac
     9301 gtgtggatac aactatgatc aagattacta gcttcaaaga tttggttgac gctattgatg
     9361 taggcattag aaatggagta tttacaatca acgaaggaag agaacgcgtt ggaaatgatc
     9421 gctctgataa ggcgatggca gatgaaatat ttataactaa aaacaatcaa caagtatcga
     9481 aaggaggtga ggcgaatgac gacaatgaaa acatttctag cagtaaagaa tgaaggcgca
     9541 gtaccgcaaa tttttattca gggatttatt ggttctagtt ggttctttga agggaatact
     9601 gacaagggaa tcaaaaatat tttggatagt ctaggtgatc aagaagaaat tgaagtagta
     9661 attaattcaa acggtggaga cgtatttcaa gggattgcta ttgggaactt acttaagtca
     9721 aataaagcaa aagttaacgt tgtgattaac ggcttagccg ctagtgctgc ttcaattatc
     9781 gcaatggctg gcgatactat aaaaatctac aacaatgcac aattgatgat tcaccgcgct
     9841 tccacatacg gagaaggaaa tgtcgatgac ttccgtacga ttgctgacca actggaatca
     9901 attgataaat cggtaaaggc ttcatataaa acacgattca atggcacaga tgaagcattg
     9961 caagaacttc ttgaaaaaga atcgtttatg gatgcagaaa cagctttgag ttatggattg
    10021 gtcgatgaaa ttatcgatgc agaaaatagc tcaggtactg aagctaaaaa agaacaaagc
    10081 gttgaagaaa ttttgaatga cgttaaagaa aaaagagcag aaaaaattgc tgcatttaca
    10141 gcagcattaa ataaaacatt tggacaagga gatgtaaaat aatgacagtt aaaaatttaa
    10201 aaggtgtaac agctgcaagc gaccaattga tgaaagcttt taaagatggt aacgaagaat
    10261 cttttagcgc agctatggta agcttatcta aggaaattca ggataaaatt ttagaagaag
    10321 caacagcaaa aaatcaagat caattagtat taatgaaccg tggtcagcgt gtattaacta
    10381 cacaagaaac aaaattctat aacgaagtag tgaaaaacga aggttttgca ggggtcgaag
    10441 aattagtgcc agctactgta tttgaacgtg tatttgaaga tttagaacaa tctcatccac
    10501 tattgcaaaa aattactttt gttaacacaa ctggtgtaac agaatggatt gtgtcacgtg
    10561 gagtcaatcc agcatggtgg ggtaaacttt gcgaagctgt taaaaaagtt ttagataatg
    10621 gctttgatgt aattaacatg aagcagttca agctatcagg ttatattcct gtatgtaagg
    10681 caatgcttga tttaggtcca gtatggttag atcgttatgt ccgtactgtt ttagtagaat
    10741 cattgagaat tgcattagaa caagcaattg ttgatggtac tggtaaagat atgccagtcg
    10801 gaatgatgcg tgacatgagc aaacaaacta gcggagaata tgctgaaaaa aaagcagaac
    10861 ctattacagc tttagatgct gtaactatgg gccgtttgat ggcgcgacta tcaaaattca
    10921 atatcgaagg tgtgaatgat ccgatttatc gtaatgtgaa tccttctgat gtggtcctaa
    10981 ttgtgaatcc aactgattac tggtctaaag tattcccagc taagactgta ctaactgcta
    11041 atggagaata cgtacaagta ttgccagtac cagtttcaga tttgcagtca acggctgtgc
    11101 cagaaggaaa agcagttatt ggggtagcct cagattactt catgggtgta ggatctacac
    11161 taaaaattga agcttcagat gaataccatt ttgttgaaga cgaacgcatt tatctagcta
    11221 aacaatatgc aaacggtcaa cctaaacgta acgatagttt cattgtatta gatattagcg
    11281 ctttgggaac tactactaca actacaaaac caacaaccac aacaactaca acacaagcgt
    11341 aggtgatcag aatgaagtat attctttgtc agccggcaat caatcggttt aaatgggagc
    11401 ttgaagtttg tttaactaat ctgaagaaac taggaatcaa agatatcgta ttgcttttca
    11461 gcagacacga tgatcagatt cctatttttt ttgagaagga atatggtgtt gaagttcatg
    11521 tgtacgatga tctgcgggac gacaaagagt atattccttc gattaaacca tatttatggt
    11581 ggaaatattt agaagaagat cattcgcgtg aggacgaccg atatttctat atcgattcgg
    11641 atgtcatttt caataaaaga attaatttgc gcaaattgcc ttctaaagat gatgtttggt
    11701 attgtagcga ctgctgtagt tatctaagtc ttgattatat tagaagctgt gaaaacggag
    11761 aaaatattct aaaagatatg gcaaacattg taaatgttac agtagaatct ttggaaacta
    11821 taaacactaa ttcaggaggc gcacagtggg ttattaaccg tcctaaagcg aattattgga
    11881 aaaaggttta tctggattct aatcggctat atcgctacct tagagggcaa aaaacaaata
    11941 tacaaatctg gacagccgag atgtgggcac ggctttggaa catgatgtat ttcaatattg
    12001 gtcctaaagt tcacgaggaa ttagactttt gttttgctac tgatccaata gaaaaagtta
    12061 aagaagtaaa aatcttacac aatgctggag taacaacaaa cgatgaagat ttatttttca
    12121 aagggagata cgtgacttct acgccttttg atgaagattt atcatttgta aacaagaaaa
    12181 aatgctctta cgcatatgtt aaagcaatta aggcggtggt tagatgacgc ctgaacaagt
    12241 gactgaagaa ttgctaatag ctgtgaagga taatatttac gttacctgga acgaagaaga
    12301 tgagtcaatt aaaaagatga tagctaaaaa tgctgtttat cttcaaagta aagtgagtac
    12361 aacactttct ttttctcctg aaagcttaga atacggattg ctaatcgaaa gatgtagata
    12421 cgactggaat cgtgctttag atgagtttga acaaaatttc gctagtgagt tattaggttt
    12481 cattcaacat tatgcgctac aagaatatat tgcaggtgat gtgaatggcg aataatcgta
    12541 gactcgaaga aacattcaac gatggttggt taaagatttt gacgcaaact accaaaagaa
    12601 atgaactagg aaaaaagatt ggtgtagaag atacagaaat cacttcttta aaatttagaa
    12661 atctttccat gagagatagt gatataacag ctatggatgc gatgggatcg aaattaacta
    12721 agaaagtaaa gactccattt catccaatcg ccaagaaatt taataaagat caatatttta
    12781 tcgtaatcga tagtatgcgt tacaacgtta tctatgccga ttacgataat ttttatatct
    12841 atttttatct tgaaagtgtg ggtgaatatg gtgattgata attctaaaga aaaagaacgt
    12901 ttaaataagc aaatttctgc tatcaaaact tccttagaag agcattttgg cctcaaactc
    12961 tttcaagact ccgtaggcga ggatgagcta cctgatgatt ttaattactt cattctcgaa
    13021 acaggagaaa tagaaatgat cactgagcca aaatatagcg tgggtcaaaa tctatatcta
    13081 actttctatt cagaaaatag agaagattta acaggagact cactagatat tatttcattg
    13141 attcaaaatc gttcgattcg ttttcagaga atggatccca atcatttaaa actagagaac
    13201 caagatcgct atatcgatca attggtattt acgtttagac gattattgaa gagtgattgt
    13261 catggctaaa aatagttggg agctaaaaat aaatggacat gatgaacttc ttgtgcggat
    13321 ggaacgctat tcaagcgaga gcgaacgact gattaacgaa gcattgaaat caaaaggttc
    13381 ggctattgca gtggatagga ttacagaaaa aattcctgtt tctgaagcag atttaagaag
    13441 agggcaccaa cacgcaaaaa atagtcgtcc acttaagact caatacatta atttgggttt
    13501 catcattaga cctacaagaa aatttgagta tttaaaatat cctgatttgg ggataggtac
    13561 ttctaaaaga aatcagccgg acgaatttat gagaagagga ttaggtcttg cacttgatcc
    13621 aattacagaa cttctgattc gtcaattcga taaattaaat aaataggggg aacaacaatg
    13681 gctaaaacaa aaactgtagt aacaacgttc gataacgtaa gtatcaaacg aattgctttt
    13741 aattttaaga acgcaggaaa tgcaatcgca acgaattgta atggacaatt agatggcgaa
    13801 acagaaatgc aaacggtggt taaaaaatgt ggagcgacag aagtaaaatc aaaatctaaa
    13861 ccaatcaata tgacggtaac aattactgca catgtaccga tggaagttta tcgacgtttc
    13921 aatgggttga aacaagatgg acgtattaaa ccaggcattt actcttacgg tcctgattcc
    13981 gtaggcgaag atttctcact tgctgcagag atcgtggatg acttcgaaga aaatagaaag
    14041 ttagttggta tgttagcatg cacttcgaat acaggattaa cattctctat tgaaaatggt
    14101 gcggatgaag tagctgcgtt agaactagaa acaaaagtta tgcaagatga atttggtaaa
    14161 ttttatcatg aagcaattgt tgcagaactt gaagaagact taacagatca atggatgacg
    14221 aatctatctg ctgatgtgat taaaaaaact tcagttgtga caactacggc cactcaatca
    14281 cagtaaaaaa aacggaggta gcgaaatgaa cgaagattac tcaaaaattg aactaaacga
    14341 tggaacaatt ttgaatttag aacctaaact gaatatcaag aaattattga tgatcaatag
    14401 agattttaac acagacgagt ttgcaaaaat gactgtggga aaaggatcca tggatatttc
    14461 tgttattcaa ggtgcaaagg ctgtgtatat tgcttaccgc caagcgaaca tgactgatta
    14521 tatttcattc gatgaattta tcgataaatg ggattttgat atggctactg ccagctatat
    14581 ttatcaattg atgatgttca aacaagcacg cgatgcttat caaaaagaat ttgaaaaagc
    14641 aaataaggaa aaaaagcttc aaaagtaaaa atgccaaagc tcttagttga aacgtgggtc
    14701 gatgtctatt cgatgttgac cgacgttttt tctatgcctt cagatttggt tttaagcgat
    14761 atctgtttag atgacatttt gcaaatggct tacaacaaga gtgcttatga aggatggaaa
    14821 aactatgcaa taaaccaatc tcagaaaaac taaagaaagg aggtaaaaaa tggctaaaaa
    14881 gagaacagaa gcagaagtaa ctttcatagc taacgatgac ggattgaaat ctacgttaaa
    14941 agaaatcagt gctgaattaa ctaaaaatag agcagaatta aaactagaac aagctcaatt
    15001 acaacagact ggttctgaat cagacaagtt aggaagtaaa ttatcttctt tagaaaagca
    15061 gtatgaatta caaagccaaa aagttgaagt aactagccaa cgtttagcca atgccaaaaa
    15121 atattatgga gaaaattcca ccgaagttca gaaacttgag agagaactga ttaaccaaca
    15181 aacagcgcaa caacgtttgt caaacgaaat tgataaaacg agtaatacac tagctcaagc
    15241 aaaaggcgaa atacagacgt acgagtctac aatgcaacag ttggatagtg aacaaaaaaa
    15301 tgttcaagct agtgcttctc tgattgaatc cgaatacaaa aaatggcaag taactgctgg
    15361 tcaatcagct tctgaatccg agaaattagc gaaagcccaa gaatatgttt ctcaacaatc
    15421 tgaaaatgca gagaaaacga tagatatcct gagacgacag ttagaagcta cacagtctga
    15481 gtttggcgct acatccacag aagcaatgca gatggaggcg aagcttaatg atgctgaacg
    15541 tgaatttgaa gagttaggac aagctgctaa aaatgtagat acaactaact tggacgatat
    15601 cggaagcaaa atagatatga ataatttaat ggaagcttct gacgttttaa gcgacattgg
    15661 cgataagctt acagaattag ggaaacaagc agtggactct gctaacagtg taggtagttc
    15721 ccagagtaaa atacaagcta attttggttt gactaaacaa gaggctgaag aattaacgaa
    15781 tgtagccaga gacatttatt ataaaggttt tggagaatcg ttagatcagt ccacagatgc
    15841 attgattttg gtaaagcgta atttaggcga tttaaataat caagatttac aaaatattac
    15901 ggaacaagct atggtcctag aaaacaccat gggcgctgat atggatgaaa cgttacgtgg
    15961 tgtaaatggc ttaatggtca acttcggatt gagcgctcaa gatgcaatgg atttaatggt
    16021 ttcgggtact caaaacggtt tagataaaac gcacgaatta ggcgacaata tggcagaata
    16081 tagccaatta tggagtcaaa tgggatattc agctgatgaa acgttcggaa tgcttcaaaa
    16141 tggtttagat gcgggtgctt ataaccttga taaagtcaat gacttagtta aggaaatggg
    16201 aatatcgtta acagatggtc gatttgagca aaacatggat atgtttagtg aaagtactag
    16261 aaaagctttt gaagagtgga aaaatggtgg aggaacacaa aaagacgtta ttaattccat
    16321 gattcaagat tttagcaata tggatggtca atacgaccaa ttaaataaag cttctacaat
    16381 ttggtctgca cttggcgaag ataacgcgat gaaagttgtc caatctttga ctgatgttaa
    16441 ccatacattt gatgatgtta gtggatctgc acaaaaaatg aatgaagatt ctactactcc
    16501 gttacaagaa ttaaacggaa aaatagctga attaaaggat tcattagctc ctataggcaa
    16561 cacaatcata gatgcactcg aaccagtaat tgattttcta ggaaagatgg ctgatgcgtt
    16621 taataatctt ccacaaccag tacaggatta tgccgtagcg attggcggat tgactgctgc
    16681 atttacttta ttaatgccaa taatagttgg cttcatggct ctaggtggtc ctactacatt
    16741 aataatagga gcagttatta ctgctattgc tggagttata gcaattataa aaaactgggg
    16801 cgcaattact gactggttta agggaatatg gagtaaattc actgattggt tgggtggtac
    16861 ttgggaaagc ataaaagaag gtgcctcatc agtttgggat ggagtcaaag aaacctggtc
    16921 tggatttgta gattgggttc aagaaatttg gcaaggagtt tctgattggt ttggagagtt
    16981 atggagcgga ttagttgaag gagcttccaa catctggcaa ggagtccaag agacttggca
    17041 agcattcgtt gattgggttt caaatatttg gaacggagtc aaagaagtat ggtcgattat
    17101 ttgggcagac attgtaggaa ttgttcaaat accatggaca ttaataacgt cattgattca
    17161 agctggtatt aatattatcg tgggtatctt tgatgtagct ggacagttat taggcgcagc
    17221 ttggcaagct gtttggacac ctatttctga tttccttaaa aatacttggg atactatgac
    17281 acaatggata agcatcgctt ggaatggaat tgtaactaca ttccatacta tatttgatcc
    17341 agtagtggca tggtggaatg gtatatggac atctattagt actacggctt caaatatttg
    17401 gaactcaatt agtgcaacag cttctagtat ttggaatagt atcaagaata caatcactag
    17461 cttggtacaa gcagctgcta cagtaattca aaatatttgg tcaactgtat ctagttggtt
    17521 aggtggaatt tggaattcaa tcagctctac agcatcaaat atctggagta gcgtgactag
    17581 tagtataagc aatgctataa acgcagctaa aagtgccatt caaagtgttt ggaatagtat
    17641 atcttcgtgg atcagcggaa tttggaacgg tatcaaaaac actgctttga atctttggaa
    17701 tggaattaca agcactatta gctctaaagt aaacgatgga aaaaatgcaa tttcaagcgg
    17761 ttggtccaat ctaacaggta ttgtttccga catattcaat aatgttaaaa gcacgatagc
    17821 taatatatgg gaaggtatca aaaagactgt tagcgctccg attgattgga ttagagataa
    17881 aatcagtagt gtctttgata atttgaatat ttctatacca catattccgt taccacattt
    17941 taaattgagc ggagaattca atccattgaa ggggaaaatc ccaacattgg gtgttgattg
    18001 gtatgcgaaa ggtagtgtgt ttaattctcc aaatattatc ggtgtaggtg aatcaggacc
    18061 tgaagcagtt ttacctttga aaagatctgt gctgcaagaa attggtgatc gtatcttgag
    18121 tagcacctca gtttcatcta ggacacaagc ggttcaacct gtgaacaatt acgaattcaa
    18181 tttcacaatt gatggtaacg cagatgaagt cactatgaag caaacaactc aacaaatcat
    18241 tgatagcatt acaaaagttc aaaatgataa tgcttcggca tggcgttaaa caggagagta
    18301 tttctcctgt ttttttagta ttaaaaagga tgtgaaaaaa tgactgattg tatacattct
    18361 ataatcgatg gatttcctga ttatttgcat aaattggctt tagctgaaag accaaccata
    18421 ccttctccaa aaagacagag agttgaaact tctgttttag gaaggttagg tggcttagtg
    18481 caagattact cgtttgaaga catgtcgttt acattgcact ataactattt agaggatgtg
    18541 gaagaccatc aagcgttcaa gcaatcgttt tatatcatgc gtcattggtt aaactatgca
    18601 aagaaattag aattctctga cgatcccaac gtctattacg ttatccagac tatcgatatt
    18661 ggggatgcag aaaacgatat tgttgaatgg ggagagttcg atgtaaatat tactgcgaaa
    18721 ccattcgcaa gagttcaaga agatgtacct ataaccgtag ataaaccaca gtcatttaac
    18781 ttgctgaata atagtttaga agaaagtttt ccaaagatta tcatcactcc ttcagctact
    18841 tcatgccagt tcatcttaaa tgattatgtg tttagtttcg aaggcttagt agcaggaact
    18901 gatgtagtca ttgatagtga tttgatgctt tgctacgaag agcaatcgga cggagatatt
    18961 ttagatcggt ccaacaaaat gaagaccatg caatatccga cattgcaagt ggatatcaat
    19021 cattttaatt gcactggttt gagcaaaata caaatttatc gtaacgggtt aaggtaggtg
    19081 aaatagatga tcgataattt aataactatt tacgataaaa atgacgcgaa taatttagct
    19141 gaacatttat atgatacgca aggtttaggc gctttgtcag actggttaac agctactgtt
    19201 agcaataaac taaacggagc cgagatattt cagggtactt atccaataag cggaactaat
    19261 gcagatttga ttgtagaagg acgtattatt cagtgttatg tagatgaaaa tcgagcaaaa
    19321 cagcgtctac ggatttatta tgcaaaaact tctgtaatag gcaatacgat agaagtaaaa
    19381 gctgaaccta ttttcaatga tataagaaaa tcggtgttga ataaatatga cagcggaaca
    19441 gaaaaaatca ctgctactca ggcatggcaa aacgcaaaag ctttagcgaa accagctatc
    19501 ccttcgcagt tttctttctc gtcattagta gatacgcttg ctaatgtgaa gatagaaaaa
    19561 gcgaattttt tagaattctt tggtggaaaa gagggatcta ttctagatcg atttcatggg
    19621 gaatttctta aagataataa cacattacat catgaaaaaa ggctaggtac ggatcataaa
    19681 atcaaagcga tttatactaa aaatttaact ggtcttgact tagagataga tgctcaaagc
    19741 gttttagttg gagtttatcc attcattagc agttcttcag aaggagaaga cgagatcact
    19801 ctaccagaag aagtcatttt cacggattac gtggatgatt atcctgctgg atatgtttct
    19861 tttgttgatt ttaaagacaa agcgactgat gtagccacat taagggaagc tgctaaagac
    19921 tggttgaaaa caaacataga taaacaaaaa ccacaagtga gtggttcgat tgaattagta
    19981 ccattgaggc atcaaagagg ctatgaaaaa tttgttgatc tagaaaaagt ttcgatgggt
    20041 gacggagtag atgtgtatca tccacagtta aaagtgaata tgtcagcgag aattgtggaa
    20101 tatacgttta atgttctaac caattcatac gataaattag ttgtaggaaa cgtcaaaaca
    20161 aacttcttag aaaacacaga gaataatgta agcaatttga ttaatgatgc cattgatcaa
    20221 ttgaaaaatg gtggcgaaat cagtgattta atcaatgata ttgtagatca tcaaactgat
    20281 atgattactg gtcaaaatgg tggttatgtt ttattagatc ctaaagaagc gcctagtcgt
    20341 attttgatta tggacacacc agataagaat accgcaagga atgttttaca aatcaacaat
    20401 gctggtattg gtttttctaa aactggcatt aatggaacat atgaaaccgc atggacatta
    20461 gatggcggat tcaatgcctc gtttattacg gctggtgaaa tagtaggaat tactattaga
    20521 ggtactacat taattagtga tggcactgat tatagaacaa gtattgctaa tggcaaaatg
    20581 acttggtact caaaaaaagt taacaaagat attatggagc tagaagcacg tgattatgta
    20641 agtgctgatg ccggtattgt atcatacacc atgaaaactg gtggtggttt catgattaga
    20701 aatccacagg gtaacttggt ttttagtacg tgggataatg gtaataacag accgtttcta
    20761 tcttttggtg cgcccaattt caggtatagc aatgctagtt atgtaacttc tggcgacggt
    20821 agttctttaa gcattaatgg tagtgcgggt aactcatggg aatttaaggt agctggtagg
    20881 actatgaaat ttactagtga tggtatgcta acgttgccag gttgtttttt tggttcatgg
    20941 gaagatggga aacttgctag gtttgaacaa tcaacggtac aagtatataa agattttact
    21001 gttagaggta ctaaaaactc aaccgtacca acagaacatt atggacaacg actattaaac
    21061 gcttatgaaa ctccagaata ttatttcgct gattatgggg aagccgttac aggtgatgat
    21121 ggtaaagttc gtgttgatat tgaccccatg tttgctgaga cagtaaatct aagtcgatat
    21181 atgacacatg tgacacctac agaactagtt ttgtgtgctg ttactcatga agatattgac
    21241 catttcatca ttgaaactag taagccaaac gtattagtta gatggaattt agtggcacac
    21301 cgtctagggt atgaagatat tagattaaaa gaggatacag catatgatag cacagtgctt
    21361 gaccaaaaac gtttttaaaa cgaagacaag gaggtatata aatggctagc agtttatata
    21421 atttggctct agatttcagc aaagaattaa actacaccaa agctattatg gctcgtcaag
    21481 gtgataaagg gattacagtg actgttaaac catttttaaa tggcttgcag atggatacga
    21541 gtggcggaac atttacttta aaaggaacaa cgccatctaa ccgttacgta gatagtgtgg
    21601 caactagtgt aactagtgaa gaagtcacgt tttctcttga tggcacattt atgagtgaag
    21661 caggatatta taaacactgc tacgtagaat atagaaaaga caatcaaatt ttaacaacgc
    21721 aagatatcat ttttttctca ctaggagtgt ctgacatttc gcaaggccaa gccgatgaat
    21781 acgtttcgca attggaagag ttgattcaaa agtataacga aacttttgat gcttttatgg
    21841 ctgaaatcga aggtagagtg gacagcttaa ataaacagat tactgattta actggtcaag
    21901 ctaaaacact acaagacaag ttagacgctc tgaaagaaga aatttctaaa ttaggtaact
    21961 tgcaggtgat gtacagtaac agcatcga
//
LOCUS       DACGDM010000037        21887 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.037, whole genome shotgun sequence.
ACCESSION   DACGDM010000037 DACGDM010000000
VERSION     DACGDM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.037"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            59..613
                     /locus_tag="IXR05_001532"
     CDS             59..613
                     /locus_tag="IXR05_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4260042.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(786..1259)
                     /locus_tag="IXR05_001533"
     CDS             complement(786..1259)
                     /locus_tag="IXR05_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4260043.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1271..1807
                     /locus_tag="IXR05_001534"
     CDS             1271..1807
                     /locus_tag="IXR05_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4260044.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            1847..2218
                     /locus_tag="IXR05_001535"
     CDS             1847..2218
                     /locus_tag="IXR05_001535"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4260045.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2502..3773
                     /locus_tag="IXR05_001536"
     CDS             2502..3773
                     /locus_tag="IXR05_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAQ4260046.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4018..5043
                     /locus_tag="IXR05_001537"
     CDS             4018..5043
                     /locus_tag="IXR05_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4260047.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5337..6446
                     /locus_tag="IXR05_001538"
     CDS             5337..6446
                     /locus_tag="IXR05_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4260048.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6529..7425
                     /locus_tag="IXR05_001539"
                     /pseudo
     CDS             6529..7425
                     /locus_tag="IXR05_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7441..8265
                     /locus_tag="IXR05_001540"
     CDS             7441..8265
                     /locus_tag="IXR05_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4260049.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8297..9607
                     /locus_tag="IXR05_001541"
     CDS             8297..9607
                     /locus_tag="IXR05_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAQ4260050.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9755..11014
                     /locus_tag="IXR05_001542"
     CDS             9755..11014
                     /locus_tag="IXR05_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4260051.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11024..11896
                     /locus_tag="IXR05_001543"
     CDS             11024..11896
                     /locus_tag="IXR05_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4260052.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            11908..12738
                     /locus_tag="IXR05_001544"
     CDS             11908..12738
                     /locus_tag="IXR05_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4260053.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12778..14961
                     /locus_tag="IXR05_001545"
     CDS             12778..14961
                     /locus_tag="IXR05_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4260054.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15022..16242
                     /locus_tag="IXR05_001546"
     CDS             15022..16242
                     /locus_tag="IXR05_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAQ4260055.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16239..17699
                     /gene="gtfA"
                     /locus_tag="IXR05_001547"
     CDS             16239..17699
                     /gene="gtfA"
                     /locus_tag="IXR05_001547"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAQ4260056.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17776..18882
                     /locus_tag="IXR05_001548"
                     /pseudo
     CDS             17776..18882
                     /locus_tag="IXR05_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19204..19413
                     /locus_tag="IXR05_001549"
     CDS             19204..19413
                     /locus_tag="IXR05_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4260057.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19406..19555
                     /locus_tag="IXR05_001550"
     CDS             19406..19555
                     /locus_tag="IXR05_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAQ4260058.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19590..20374
                     /locus_tag="IXR05_001551"
                     /pseudo
     CDS             19590..20374
                     /locus_tag="IXR05_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(20658..21743)
                     /gene="xerS"
                     /locus_tag="IXR05_001552"
     CDS             complement(20658..21743)
                     /gene="xerS"
                     /locus_tag="IXR05_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAQ4260059.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         7440 a         3297 c         4212 g         6938 t
ORIGIN      
        1 tatggtaaaa tatatacata atcattaact cagaatattt ttaagaaggg aaacaatagt
       61 gagctataat gtacaaccgt taaggacaaa tgaagagata caagattttc agttttggct
      121 aagaagaaca agtaatccgg aaagagatag ttttttattt ttgtttggaa tcaataatgg
      181 gttacgtatg tcagatatta taggattaaa agttggagat atacgaggca aaagtaagcc
      241 tattattgtt gaacataaaa caggtaagcg aaaaccgatt tttatagata atttgagaga
      301 agaaatttta ttatatactg aaggtaaaga agaaaatgat tggttatttc cgagtcggca
      361 acaaggtcga catataacaa gggatcgtgt ctatcagata tatgcagata tagcagaaaa
      421 attaggacga gatgatatag gaacacatac attaagaaaa acttttgggt atcactacta
      481 caagaaaact agagacattg ctaccttaat gtttattttt aatcatagct cgcaagcaat
      541 tacaaaaagg tacattggta taactgaaga tgaaatagga gcatcacttc gtggatttaa
      601 actaggtgta taatttaaaa atttttataa acagtaaaga caaagattaa aagctatttt
      661 tatctagaac gattttattt cataaagttc gcggaataaa agctggggtt actggtactt
      721 ggtataggtt cgtgttatat aaactaagta attaaataac atttttaggt tggaaaagga
      781 tgaaattaaa aaaagagaat caatacggtc tcaaaaacgc aaacgctgcg gaataagaaa
      841 aatactgata actcaacgtt tagcagacta tctaataggg atagtctgct tttttcgttt
      901 ttgaccatac ttttgacctt ctgcaaactt ccttgctttt cctctgtaga actcatgaaa
      961 tctgcaaaac gaattgccgt ttcctctgtc tgctttttcg cgatatgggt gtatatatca
     1021 tccatagtgg ttttaatatc tgtatgtcca agtcgaacat acacttcttt gacagacgca
     1081 ccagattcaa agagcagact acaatgggta tgacgaaaac catgaagtgt gatatgtttt
     1141 aagttattct ctttaatgat gattttcaaa ttgtgattta catagtctaa ataaaggggc
     1201 ttattttctt ctgatgaaaa caaaagttgt tcaccatctt ttataggttt gattctcatt
     1261 tttagatatt atgcccgcac gtattcatca catttctatt gtgaatcgct ttattcgacc
     1321 gacatttgac ttttatcata atatactcgg tttaaaatta ctaatgaaaa caattaatca
     1381 agacgatcat accatgtatc acctgttttt ttcagataat caccaccgtg tgggaactga
     1441 actgactttt tttgaagtac aagaagggaa caaccagttt tttggaacca atacgattga
     1501 acgaacgata ctaaaagttc cttccgaagc atcattgcat ttttgggaaa tatattttga
     1561 aacacaaggc gtttgccatt atggaatcga atcattttct ggacgaccta tcttacgttt
     1621 tgaagggcca gatgcaacac gattagcttt agttccctta cgcgaatttg aagatattga
     1681 tgattatttc ccgtatgtca cagaccagat ccctacagag catgccattt taggaattga
     1741 tgccattcaa ctacgcgtac aatattccga tgcgactgaa cgagagttat tgtcggtagg
     1801 ctggtagcac aaagaatacg tcagtttctt ttcgggtcat caacgagtga caatcttaga
     1861 aaatcaagac actcagttct atcaagaagt tcagattatt caagatcgtg agaatccagt
     1921 tgccattgaa gggattggta gcgtccatca tgttgcgttt ggcgtagaaa ataaatctga
     1981 tttacaacgc atcgacaaac aattacaaga gcgcaatttt ataaattcag gaataaaaga
     2041 tcgtgaattt tttgtatcac tttattatcg tgacccaaat caattattga ttgaaattgc
     2101 tacaggggaa ggaaacctag atgcaaaagc gtatgaaaat caaagtccac gctttgaaga
     2161 aattccttta tttttaccgc agtacttaaa tttcattcgt gaacaagtgg agcaataatt
     2221 agctaatcaa atccatgacg aagagtaaga ggttgactca taagtcaaaa aataaagaaa
     2281 aacgcatcaa atccattcta aagaatgttg atttgatgcg gttcctattt ttataaacta
     2341 tcattttcga ctaataaaac tacttatgag tcagcctctc tttttttctt gatttttata
     2401 cctctttcta ggtaaactaa acatctgcca aaaataccgt gtctcattga aacattctca
     2461 actatttcaa aataaagggg agtaccaaat gaacgagtat attgaaatta tccacgcaag
     2521 agaaacaact taaaaatgtc agtctcaaaa ttcccaaaaa taaaattagt atttttacca
     2581 gcgtatctgg ttcaggaaaa tcatcgattg tttttgatac tattacccaa gaagctggtc
     2641 gtcaactgaa tgacacctat gatagtttta cccgtttatt tttacctaaa tacagtcgtc
     2701 cagaggttga tgagattgat aatctttcta cggcgattgt ggtcaatcaa aagaagattg
     2761 gtggcagtgc gcgctcaacg ttagggacga ttactaacat caatgcgtta tttcgtgtgt
     2821 tgttttcatg ttttgcaaca cctagtttag gatatgcaaa tgcttattca tttaatgatc
     2881 ctagtggaat gtgttctgtc tgtcagggaa tcggtaagac gattgcattt ttaataggat
     2941 tgctttattt ttcggctatt gataatgctg attttgtatt ttctgatcca tttaccgcag
     3001 aagttttgtc tggaattgag gaacaggcaa agaatcatgg ttattttgta ttggtgcata
     3061 atgttaattc agcagaagat gttaaaacta ttcagagaaa ttggcgtttt gaggggttca
     3121 ttgttgttgg tgtacgtgta aaagaatttt tggaattaaa taacgttttt gatggtcctg
     3181 ttgtttatat tgatacgcat ctttcaaaag agacattaag agaacttgaa caacaaatga
     3241 atcgtttatt tgtaaataca aatgattacc aagctagtac attggcagtg gaacatttga
     3301 ttcattatgg tcatgagaaa atagcgtttc tttcttttga ctacattgta ggtgaaccaa
     3361 gtgttattca agaacgacat caagcttata tcgatacatt aaagaaatat catttaacct
     3421 ttaaatcgca ttggatatat aacaactctg aatttgagcg aatttatcaa gaattagctg
     3481 aatttactgc aattgttgtt actggagatt atttagcggc taaattagta aaatttttaa
     3541 aaaataagaa taaacgagtg atggaacaat tatcgattat tggatttgat gatattactt
     3601 ttgcagaatt aatggatcct gcgttgacaa caatacgact aaatccaggt aacaaggggg
     3661 cgattgcttt tcaccaactg attggactgg ccaaacaaga agaaataaaa aatcaagtac
     3721 tactattaga gggagaattg atttctcgag actctgttca caaaatcaaa taaaaaagct
     3781 ctgtgaaata agtatagtta acaataaaat atccgaacga tagagagaat gaactgtgat
     3841 ctagcagttc ctcgtcgcaa attcactaga attagcatta tttactctaa attgttcgga
     3901 tattttttct tgtttttaat tatgattaca gtgcctattt ttaacgaaat ttgcttattt
     3961 tcaaaatgta tgattatatg ttagtaaaca ctttcaaata tgaaaagagg agctattatg
     4021 gtaggaatta gggatgttgc aaaacgggcg ggtgtgtcca ttgcaacagt atcgcgcgtg
     4081 ctaaatgagg atccgacact ttcagtaacc gatgaaacca aacgaaagat tgcagaatcg
     4141 gttaattttt atcattatgt caaaaaaagt cccgttgcaa aaaatttaac aaatattgca
     4201 ttaataacga cagtttctga agtagatgag ttggaagatc cctattttcg aacgattcgc
     4261 agagggattc aagtcgaagc agaacaaagc aaagtcaatt tgaagaaaat tattcgtttg
     4321 tcagaaacac cgttggagca agacgatttg ctaaaatgtc aaggtgtgtt gattattggg
     4381 caggtgctat cttctgtgat tgaagaagta tcagcaatta attcgaatgt cgtagtgatt
     4441 gatgacccta gtattgaagc tgaagtagat gcagtttata ctgatttaac aaaagcaacg
     4501 aatcagcatt tagatcgatt gtataaaaaa ggacaccgaa acattgcgtt tatcggagga
     4561 ggacgtgttc gtttagatag ccaaggaaat aaacacgtgt cagatgatga ttatcgaaaa
     4621 atagcctatg agacgtggat gaaacaaaaa ggattagaaa aatatagtca aatttattta
     4681 gaaggctgga ccacacttga cggaatgcag gcagcagatt tacttttgaa aaaacatgct
     4741 aaagataagt tgccgactgc tatcatggta ggaaatgatc ctattgctgt gggggtttat
     4801 cgttcacttc aaaaaaatgg tctacatatt ccagaagata tttcgattgt gagttttgat
     4861 aatattgaag ttgctgaatt tttaacacct gcattaaata cggtgaatgt gaatacagaa
     4921 gaaattggaa aactagcagt tcgcatggtt aatgaacgaa taaaagaagt tagaaatgtt
     4981 tcgatcaaag tgattgtttc taataatatt attgttagag aaagtgaaaa aaatatcgat
     5041 taaaaaagta aacatccaaa aaagggtgtt tacttttttg tttactaata tttttagtaa
     5101 aaaatctcga caaaacatta agtaaacagt tatggtgttg ttaacaaaaa gaaaacgcat
     5161 tcaaaacagg aggaattaag atgaaacatt tcaaaaaaat agctttaaca gggatagctg
     5221 ttttaactgg gacattactc gcagcatgtg gtgggggaga tagtaattct aaagacgggc
     5281 aagtaacttt aagctatgcg agttgagata ctgaccaagc tccaggacta agaaaaatgt
     5341 tagatgaatt tgaaaaacaa aatcctgata tcaaagtaga aatggagaca acgccttggg
     5401 atcaatattg ggttaaatta gaagctgcaa caacgggagg taatatgcca gatgtagtaa
     5461 ccatgcactc tagcgaatcc tataaatata tgtcacagaa tgctttgatg ggacttgatg
     5521 atgttatcaa agaaaatgat attgacatgg gaaactttac tgaaggaatt gctgatttct
     5581 atacgcttga agacgaacta tacgcaatcc ctaaagatgc ttctgtagtg gggctatggt
     5641 acaacaaaga attatttgat aatgcaggtg tcgattatcc agatgaaaca tggacatggg
     5701 aaacactcag acaagctgca attgatttaa cagatgaatc aaaaggcatc tatggttttg
     5761 catcacatat tggaacagag actggctact ggccatttat ttatcaaaat gggggagaag
     5821 tatttgccga tgacaataca aaatcaggtt tgaatacccc agaagcacaa gaagctttag
     5881 ctttttatcg agatattgca cttgttgatc atgcttcacc aacaattaca gaattacaag
     5941 atcctgataa gttaagtcgt tttcaatcag gtagattagc aatgatgatt gaaggaaact
     6001 ggtttgcacc gggatttttg aaaaatgact atctagttga aaatgttgct tctgccgtgt
     6061 tacctaaggg aaaagttaat gcaacaatta caaatggact tggttgggct gccagtgcga
     6121 gtacaaaata cccagaagaa gtgaaaaaac taatggcatt tttagctagt gaggacgcca
     6181 ataaaatcca agcggaaacg ggggcatcaa tcccagcact aaaaggcttt gaagacgagt
     6241 gggctgcttc ttcagataca attgatttga gtgcttttgg aaaaatgttg gagtatggag
     6301 tccctcgtcc atacaataaa gatggattac gagctgaaca agcagaagtt caaattatta
     6361 accgtattct gtctggtgaa gtaactgttg aagatggaac cgctcaaatt gaaaaagaag
     6421 tcaatgcgat attgagcgga aattaaatta gttaattata caatatacag gcgaaaggat
     6481 tctatttcgt ctgtatatta atggatgaat accaaaaagg gggatattat gaaaaatcga
     6541 atttttggaa aatatcgtaa agatcaagtg atatggggct atatttttat ttttccaacg
     6601 gcattaggat taattttatt aaatatatgg ccagcaattc aaacagcaat tttaagtttt
     6661 caaaaaacgg tagggttcgg tgatactgaa tgggtcggat taagaaatta ccaaaaaatg
     6721 tttgcagacg gtgaagtttt tcagtcttta ttaaacacat taatttatgc agtggtttcg
     6781 atacctagta ttgttgtatt atccttgttg gtggcagttt taatgaatag aaaagttaaa
     6841 ggattgtcga tttatcggac aatttatttt ctaccagtcg ttgctgcacc atccgcagtc
     6901 gcaatgattt ggcgctggat gttcaataat gattatggac tgattaataa catgttggct
     6961 aaaataggtc tcgatggacc agcatggtta acggatccat cgattgcgat ttattctatt
     7021 atcattgtag gagtttggag tgctattggt tataacatgg tgttattact agccggctta
     7081 taagaaattc ctaaagatta ttatgaagca gcggaaattg atggtgctag tccaatccag
     7141 cagtttttca acattacgtt accattagtt acaccaacat tattttttgt agttgtaaca
     7201 acagttatca atgctttcca agtatttgat gttattttta tgatgattac tcctaatagt
     7261 accgccatgt ttaaatcaca atcattagcc tatttattct ataaacattc atttatttta
     7321 aatgacaagg gatatggttc ggcaatcgtt atgttccttt tagtgattat attaattatt
     7381 actgcaattc aaatgaagtt gcagaaaaag tgggtaaact attaaggagg ctatcaaatt
     7441 atgaaaaata aatttttttc aaatgcgcca atccatatca tgcttatttt aggtggtatt
     7501 gcaatggcat taccttttat ttggatgatt ttaacttcag ggaaaacgtt ggttgaatct
     7561 acccaaattc cacctacaat tttccctgag aaatttcagc taagtaacta tcaacaagta
     7621 cttgatttat taccattcat ggctttttat atcaatacat ttttaatggt tgttggacga
     7681 gtgattggct cggttttatt ttcagcaatg gctgcatatg cttgtgcgcg tctaagtttt
     7741 ccagggaaaa atatcctttt cagcttagta cttattcaaa tgatgattcc cggttccatt
     7801 tttattactc cacagtattt attagcacaa aaattgggta ttttaaatac aattccagca
     7861 ttaatattac caggggtagt tagtgcgttt ggtacgtttt tattaagaca atttttctta
     7921 ggtttacctg atgaattgga ggaagcggcc tatttagaag gtgccaatat ttggacgatc
     7981 tttttcaaaa ttatgttgcc gcttgctaaa tcaggattgg ttgcacttgg aatattcaca
     8041 gcgttgtttg catttaaaga tttaatgtgg ccattgattg tcaatacttc aattgataag
     8101 atgcctttag ctccgggatt agcaaactta caaggacaat atgccacgaa cttcccacaa
     8161 ttaatggcag gttcgttatt agcaatttgg ccaatagttg tgatattcat cgttttccaa
     8221 agaaaattca ttgaaggaat tgctacaaca ggtagtaaat tataaaacta ttaattagtg
     8281 attggagagt aagtacatga caaaaattac atttattggt gcaggaagta ctatttttgc
     8341 aaaaaacgta ttaggcgatg cgatgttaac tccaagtcta caagatgcac atattgcatt
     8401 gtacgatatt gatgaaaaac gactaaaaga atcaaattta atgcttaaaa atattaataa
     8461 aaattcgaat gaaaatcgtg ctgatattgt ttcttattat gatcgcaaag aagcgttaag
     8521 agaggctgat tttgttatca atgctattca agtgggtggt tataaacctt caacagtgat
     8581 tgattttgat attcctaaaa aatatgggtt gcgacaaact attggtgaca ccatggggat
     8641 tggtgggatt tttagaaccc tacggacact accagtaatg ttagactttg ctaaagaaat
     8701 ggaagaagtt tgtccaaatg cttggttatt gaactataca aatccgatgg cgatgttaac
     8761 catgggtgtt ttaaaagcga cgagtattaa gactgttggt ttatgtcata gcgttcaagt
     8821 atgcgtacca gaattgtttg agcatttagg aatagccgat caatatgact taaatgactt
     8881 tcaatggaaa attgcaggca ttaatcatat ggcattcttg ttggaaatta caaaaaatgg
     8941 ggaagatttc tatccaacaa ttcgtcagtt agctgcagaa aaaccaaatc cacatccaga
     9001 ttctgtacgt tttgaattgt tgaaacgttt tggttactat attacagaat caagtgaaca
     9061 caatgcagaa taccatccat actttattaa atcaaaatac ccagaattga ttgacgaatt
     9121 agggattccg ttggatgaat acttacgtcg ttgtgaacaa caaattaatg attgggaaag
     9181 catgcgagag gacattgtaa ataatgggga gttaacacat acgagaagcc gtgaatatgc
     9241 ttcatatatc atggattcta ttacgacagg aactccgtca gtgattgcag gaaatgtctt
     9301 aaataaaggc ttaatcacaa acttaccgac agatgtttgt gtggaagtac cttgtttagt
     9361 cgataaaaat ggcgtgcaac caacctatgt cggtgaattg ccaacacaat tagctgcttt
     9421 aaatcggacg aatatcaatg ttcaagaact gacagtagaa gccgctttaa cactagataa
     9481 atcaaaaatt tatcaagcag cgtatttaga tccacatcta tcatctgaat tgtctttaac
     9541 agatatcaaa aatttagtgg atgatttaat cgaagcacat ggggactatt tacctgaata
     9601 taattaaaaa gaagctgaaa gagtaaggaa ttttcaattc cttactcttt tcttagttaa
     9661 atttagtaaa aatattgaca aaacacttag taaacagtta cattagtgtt aacaaaaaga
     9721 aaacgcattc aaattgtata aggaggagca taaaatgaag tggtctaaaa aaattatttt
     9781 agcttgtata gcactaggag caacgatctc tttgactgct tgtggaaaaa atcaggaaga
     9841 tgcaagcggt aaggtagaaa tagagttttt taatcaaaaa aaagaaatga ctcaaacgat
     9901 tcaggagatt gctaaagatt ttgaagcaaa aaaccctgat attcatgtaa aagttgtgga
     9961 tgtaccgaat gctggtgaag taattaaaac acgtatgctt gcaggcgatg taccagatgt
    10021 cattaatctt tatcctcaaa gtatagaatt gaaagaatgg gcgaaagctg gttatttaga
    10081 ggacttaacc gaagaaccgt atttagagaa tatcaaaaat ggatatgcac aacgttttgc
    10141 tattgaggat cgtgtatata gcataccatt aaccgctaat gtctatggtt tttactataa
    10201 caaaactgct tttgaggaaa tggggattca agcaccagaa acttgggcag aatttgaaaa
    10261 aatagtagct gagattaaag atcaaaacaa agtaccgttt gcgattgcag gagcagaagg
    10321 ctggacttta aatggttatc accaactagc tatagcgact gctgctggtg gtgaagagga
    10381 agcgaacaat gtttggcgtt tctcagaagt taatggaatt aatgctgaaa gcaaagaaat
    10441 gcaaaaagat tttaatcgat tagatttgtt aagagaacca aaagctttgc aaaacaactg
    10501 gcaaggtgcc ggttataacg atacagtagt tacttttaca aaaggtgatg cgttgattat
    10561 gccgaatggt tcatgggcaa tgccgatgat tcattcacaa aatccagatt ttgaagtagg
    10621 aacttttcct tttccagcag atgaagcagg tcaaagtcta acgattggcg caggagacct
    10681 agccttatca gtttctgcaa cttctcaaca taaagaagaa gccaaacgtt ttgtagaata
    10741 tatgacaaca cctgaagcga tgcagaaata ttatgatgta gatggtgcac cgtgtgctgt
    10801 tgagggcgtt atcgagaata ctcaggattc accattaagt ggtttaactg aacttgcttt
    10861 tactgatcgt catttagttt ggttagccaa agattggaat agtgaaaatg atttttatac
    10921 cttaacaaca aattatttac acaatggcaa tcaaaaagcc atgattaacg cattaaatgc
    10981 tttctttaat ccaatgaaag ctgacggaag gtaggaaaat aaaatgaaaa taaaagaaat
    11041 tttaaatcgt tactgggcaa tcatttttgt agcaattcca attattttgc agatgatttt
    11101 tttctacttt ccaatggttc aaggtgcttt ttacagttta actaattgga ctggtctgac
    11161 ttataatttt gattttgtgg gtttgaacaa ttataagatt cttttttctg atccgaagtt
    11221 tatcaaatcg attggcttca ctttaattgt gacgctttgc atgattgctg gacaaattgg
    11281 ttttggtatt ttgattgcgc gggcgttgaa cgcaaatatt aaagggaaaa cattctttag
    11341 agcatggttc ttttttccag cggtcttatc gggcgtggtt gtttctttag tatttaaaca
    11401 aatttttaac tatggtttac caaaaattgg tagtatgtta ggcattgaat ttttacaaac
    11461 cagtctttta ggaacaacat ggggagcgat ttttgcagta atttttgttt tactttggca
    11521 aggaattgcc atgccagtca tcattttctt agcgggtttt caaagtattc cacaagaaat
    11581 tattgaagct gctagaatgg atggggcgaa tgataagcaa attttttgga atattgaaat
    11641 cacctactta ttaccaagta tttcaatggt atttattatg gcattaaaag gtggcttaac
    11701 agcatttgat caaatttttg ctttaactgg tggtggacca agcgatgcca caacatcttt
    11761 ggggttactt gtttataatt atgcttttaa aaacaatcag tttggttatg cgaatgctat
    11821 tgctttagtc ttatttatct taattgggat tgtttcactg gcacaattaa aattatcgaa
    11881 aaaatttgaa atctaggagg tttcccaatg aaaacatcaa aagaaaaaaa tatttctaaa
    11941 tacttgcttt tattattagg gggcttcatg attttagttc ccttagtttc aacgctattc
    12001 ggttcattta aaacaacacc cgatattatg aataatttct ttcgttttcc taatccagcg
    12061 actttggaaa atttccgaag attgttagcg gatggaattg gtcattactt ttggaattcg
    12121 gcaatcatca caatcattgc agtagttgct gtgacagcaa ttattcctat ggctgcttat
    12181 tcactagcaa gaaaaatgac tcgtgggaaa gcatacggat tgatgtattt atttttaatt
    12241 ttaggaattt ttgttccttt ccaagtaatt atgattccga ttaccgttat gatgagtaaa
    12301 attggtttag caaatatgtg gggattaatc ttactctatc tcacttatgc cgtaccacag
    12361 acactatttt tatatgttgg ttttattaaa ctaaatgtgc ctatcagtct ggatgaggct
    12421 gctgaaattg atggggctag tcactttaca acttatttca aaattgtttt cccaatgtta
    12481 aaaccaatgc atgcgacgac tattattctt aatgctctat ggttttggaa tgatttcatg
    12541 ctaccattat taattttaaa tcgtgattct aatatgtgga cactaccatt gtttcaatat
    12601 aattatacgg gacaatattt taacgactat ggtccaagtt ttgcttccta tacagtagga
    12661 attgtcacga ttacactagt ttatcttgct ttccaaagaa gtattatagc tggaatgagc
    12721 aatggagcag tgaaataacc aataaattat tctcattata aaggagttca taaacttatg
    12781 attatatttg acaatcacac acaaacattt catttacaaa ataaaaaaat tagctatcta
    12841 ttaggaatcg aagaaaataa ttatttaacg catctttatt ttggaaaaaa gattacgcac
    12901 tattctggtg ggtatcgcta cccccgaaca gatcgttcct tctcacccaa caatgcaaat
    12961 gcgcaagatc gtttattatc tttagacaca ttaccattag aatttccagg atatggacat
    13021 ggtgatttta gagaaccggc gcataatatt aaattaggaa acggtagtcg tgtaaatgat
    13081 tttcgttatg atagctacga aattcaaaaa ggaaagccca gcttagcggg attgccagcc
    13141 ttatatacgg aagatgatga tgaagctgaa acgctgatta ttcaattgaa agacgcgatt
    13201 agtggattga ctttacagtt gttctacaca atttatcaaa atcacagtgt aattattcgt
    13261 tctacgcaat tagtaaataa tagtgatgaa acagtggaga ttaaccgctt agctagtcaa
    13321 tcaattgatt ttccaaatcg tccactcgag ttaattcatt taaatggtac ctgggcaaga
    13381 gaacgtcaaa tgactagaga aaaaattcat acagggataa aagtattaga tagtaaacgc
    13441 ggatcaagca gccatcaaca aaatccgttt gttgctttag tagatgccaa aacagatgaa
    13501 tttcaaggag aggcatatgg atttaattta gtttatagcg gtaatcacga aacggtgatt
    13561 caaaaagatc catttgacca aacacgggtc attatgggaa ttaattcatt taattttggt
    13621 tggcaactaa aaactggcga ctcatttcaa acgccagaag tcgtgatggt ttatagtaat
    13681 gaaggtctga atacgttatc acagacgtat catgaattgt ataatcaccg tttaattcgt
    13741 ggaaactatc gtttaaaaga acgtcccacg ttaatcaaca actgggaagc aacgtatttt
    13801 gattttaacg aagaaaaaat catgaatatt gtcgatgatg cgaagaactt gggcattgaa
    13861 atgtttgttt tagatgatgg ttggtttggc ggtcgtgaaa atgacttcac ttcattaggt
    13921 gattgggttg aaacagaagg caaacttgct tgtggtttgg aaaatttagc caagcaagtg
    13981 catgataacg ggatgaaatt tgggatttgg tttgaaccgg aaatgatttc tgaagatagt
    14041 gaactatttc gagcacatcc agattgggca ttgggtattc caggtcgtga ccgctcaatt
    14101 agtcgaaatc aatatgttct tgatttttca agacaagatg ttcgtgataa tatctatcaa
    14161 caaatgacgg cgatttttga tcgtgtaccg attgattatg tgaagtggga tatgaatcga
    14221 aatatgacag aagtctattc tgtcttgttg gactcaacga tgcaaggtga agtggctcat
    14281 cgttatatgt tagggttata tgaattttta gaaaagttaa caacgaatta tccaactatt
    14341 ttatttgaaa gttgttcggg tggaggcggt cgttttgatg caggtttctt gtattacatg
    14401 ccacaaactt ggacgagcga caataccgat gccgtggctc gtctgaaaat tcaatatgga
    14461 accagcttag tgtatccaat ttcaagtatg ggtgcgcatg tttcagcagt cccaaatcat
    14521 caaacaggaa gagaaacgag tttaactatt cgtggcaatg ctgcgatggc tggtgttttt
    14581 ggttatgagc tagatctaac gcaattaact tctgaagaaa aagcagaaat taaagaacaa
    14641 gttgcctttt ataaaaagca tcgccaactt ttgcaatatg gaacttttta tcgcttggaa
    14701 agtccgtttg aaggcaatga tactgcatgg atgtttgtct caaaagacca aacagaagcc
    14761 atggtctttt atttccgagt attagcagaa gctgcgcatc cattagtcac attgaaatta
    14821 gcaggattag cagaagaagc aacttatcaa atggaagatg taacatttgc tggcgatgaa
    14881 ttgatgaatc tcggttttta tattgactca gaactacatg gtgattatgc gacacaacgc
    14941 ttttatttga aacagatata gtagcttgaa tttacaatat aagtgcaaca ccaaaagaga
    15001 ctcattccaa acgaagaaaa tatgttttat ttacacgcat ttactaaaaa gcagcctgat
    15061 ttgaattggg aaaatgaaga agtacgtgaa gaaatctatg caatgattaa ctattggtta
    15121 gataaaggac taggcggatt tagaatcgat gcgatattaa acatcaaaaa aaaactagag
    15181 tatggcatct ttgaatctga tggagaagat gggttagcct tcattgggcc ctggattctt
    15241 aatcagtcgg gcattgaagt gtggttaaaa gaaatgagag agcggacatt taaaccacat
    15301 aatagtatga cggtagcaga agccgatgtt cctaatgaac gtttagatga atatattggt
    15361 gaagatggct attattcgat ggtttttgat tttagttata cggatattga tgtacctgaa
    15421 actggtgaat ggtttaaaga tagccaatgg acatggacgg atatgcgtac caatattttt
    15481 acgaatcaat tagttacgca agataaaggt tggggcgcct tatatttaga aaaccacgat
    15541 caaccacgtt caattaataa atatattcca gaagaatgga tcaatgatta tagtaaaaaa
    15601 atgttggcga cgctttttat gttactaaga ggtacccctt ttatttatca aggacaagaa
    15661 ctaggaatga ccaacataga aatggcatca ttagaagatt ttgatgatgt agctacgcat
    15721 tctcagtata aacgggcatt agaatatgga ttggcaccag agcaagcatt gaaagctgtc
    15781 aataaacgaa gtcgggataa ttctcgcaca cctatgcaat ggaatacgca aaaaaatgcc
    15841 agattctcaa cttctgataa tgtatggtta aaagtaaatc ctaattatcc agaactcaat
    15901 gcagaagctc agttaaccaa tcaacagtcg gtattcaatt attatcatca attaattaaa
    15961 ttaagaaaaa atagtgtata caaagacgtg ctaatctacg gacaatttct accagtgaaa
    16021 gataaaaatg aacatatttt gctttatgaa cgccaattag aagataaaat cgtattagtt
    16081 atcttaaacg ttacagcaac agaacaagaa tattatgtag atgaacagta ccaacaagta
    16141 ttaatcaata attatgaaga tgttttatta gatcaaagtc gaaaattgcg tttacgaccg
    16201 tttgaaagta ttgtattagc taattatgga ggacaattat gaaaattaaa aacgaagcaa
    16261 tgctcatcac ctatgcagat agtttaggaa aaaacatggg cgaattaaaa caagtcttag
    16321 acaaacattt acaaggtgtt attggtggtg tacatctgtt gccttttttt ccatcgacag
    16381 gtgatcgagg ctttgcgccg agtgattata cgacagttga tccagctctt ggaacatggg
    16441 aagatgtgga agcattaggt gaagattatt atttgatgtt tgattttatg attaatcaca
    16501 tttctcgtga atcaaaattt ttccaagatt tcaaaaaaaa ccatgagcag tcaccataca
    16561 aagaaatgtt tatccgtatt catgaatttt tcccagaaaa tcgaccaaca caagaagata
    16621 ttgatttaat ctacaagcgt aaagacaaag cgccgtttca aacggtagaa tttgcggatg
    16681 gtacgacaga agaggtttgg aatacctttg gggaagaaca aattgattta gatgtgacca
    16741 aagaagttgt gaaagaattt attcgagaaa ccatcaaaga tatggcgaac catggctgtt
    16801 ctttaattcg attagatgcg tttgcttatg cgattaaaaa attagatacc aatgatttct
    16861 tcgtggaacc agatatttgg gaacttttag acgaagtgcg tcaagaagca gcgaaatatg
    16921 acgtcgaatt attaccagaa atccatgagc attattccat tcaaatgaaa attgccaatc
    16981 atgattatta tatctatgac ttcgccttgc caatggtcac tctgtattca ctttatagtg
    17041 gaaaatcaga acgtttagcc aattggttga aaatgagtcc gatgaagcag tttacaacat
    17101 tggatacgca tgatggaatt ggtgttgtgg acgctcgtga tttattaaca gatgaagaat
    17161 tggattacac ctctgaggaa ttgtataaag tcggggcgaa tgtgaagaag gtctattcaa
    17221 gtgccaatta caataattta gatatttatc aaattaacag cacctattat agtgcattag
    17281 gcgataatga ccgtagctat ctgttagcac gtgcgattca agtatttgcg ccagggattc
    17341 cacaaattta ttacgttggg ttattagcag gaaaaaatga tattgaactg ttggaagcaa
    17401 cgaaagaagg gcgtaatatt aatcgtcatt actatgattt agccgaaatt gaagaagaag
    17461 tgcaacggcc agtgattcaa caattatttg cacttttaaa atttagaaat gaatctgcgg
    17521 cgtttgattt ggatggaacg attgaagtag caacgccatc agaatcagaa atagtgatta
    17581 cacgtaaaaa taaaaacggt agtgatagtg caacattaac ggctaacttg gatacgaaag
    17641 aatttatcat tgagtctaaa gatataaaaa ttttcactag tgttgcatta aaattttaac
    17701 ctattccata gaacaaaaaa tcctttatac tagcacttgg atgacttatc caagaccaat
    17761 aaaaaggact catacatgga taagtataaa acaaatacag catttaataa atggttttct
    17821 gccataaaat taggaaaact ttctgtcaac tcccaaaaat gtatttttga ttacaattcg
    17881 tatcgtaaaa aactgtcttt tgaagctgtg ctcaagctct ttctctacgc agttaatgaa
    17941 gaaaaagaaa gtttgcgtga tttgagtaca gctcttatcg accgatcgct ccaactagaa
    18001 accgatgtgt catcgattag tcatacccaa ttgtctcgag catttaatgc acttgaacct
    18061 aaagtgttag aagaaatttt tcaacaactg ttagaaaaag ttcaacatca aatcaaacca
    18121 accaagcgaa atcatctgta tctgattgat tccagtacgt tttcgcttag tttaaaacgt
    18181 cataagtggg cgactttccg tcaaacaaaa tcaggtgtca agttacactt aaactattgt
    18241 tatatggacg atactacgat gtatccaact gattttacct taacaaatgc ccatgaacat
    18301 gatctcaatc aactaccagt attggtgaat caaccagagg caacttacgt gtttgatcgt
    18361 gggtattagg actttgaaaa gatggatcag atgcattggg atggctattt cttcgtcact
    18421 cggattaaaa aaaacaccaa agttcacgtg atagatactc tggaaacatc gccagaaaca
    18481 gaaattctac gagacgagct ggttcgttta ggatctaaaa cctatctaac cgccaatttc
    18541 cgactagtca ctgttcaaga taagaacgga cgtgtgtttc aatttatcac caatcgaatg
    18601 gacgtctctt caaaagaaat ctctgatatg tatcacgctc gttggcaaat cgaattgttt
    18661 ttcaagcaca tcaaacaaca catgaccatt aaaaccttct tttctcaaag tgaaaaaggc
    18721 gtgcagaatc aattgatttt aacgatgatt tccgctctcc tcacgtttct catcaaattg
    18781 gagacgaaaa cggaaaaatc agtgttccaa atcaaacgat tctttcgtta tttactgttt
    18841 cagccctttg aatgttgtct agaaaaatta attcccacat gagaaaaaag aaatttggct
    18901 cgttactttt ggttttcagt tgaataacag ataaaaaatt ttctggaaaa agtcatcctc
    18961 tgcgtcagca cagttttttt tgacttattt tcagaggaaa tagttttcag aatattctaa
    19021 aatgttttat gcaacactag tgatattttt tagaattaga tttctaatgt gcattttttg
    19081 agtattaagg agcaagtata caaagattta taaagctgat taaatttgaa taaaaatatg
    19141 caggaacgct actattttta gtagtgttct tttttatatt tgaataaaaa atgtggtggt
    19201 taaatggtgg ttataacaaa aaatgaatta atgaaattag gttatgggaa gtatcagtct
    19261 gagagaatca tacgacaggc aaaagcaatt atggtttcaa aaagctatac ctattacgaa
    19321 aatagaagat taggactagt acctgttgaa tctgtagaag aagttttagg tatgaagata
    19381 gaggtagagg aggattttca gaatcatggt taattttaaa aaagataaaa atgggaaata
    19441 tcattttact gctagtttgg gattcgacaa acgaacaggg aaaagagtac aaaaaaacgt
    19501 agaggggtta aaacagttaa agaagaaaaa aagcgtatac cgaacttgtt tctaattatg
    19561 gaaaagaagc agaaacttct caaagtacta tgttgtttga ggagtttttt tataaattat
    19621 tcctacctta ttatcaaggg aaagtagaag aaagaacata taaaaatcgg ttatctacaa
    19681 tcaaaaaaac ttttcttatt tctttaaaat ggagttaaga gaaatacgtc caattgacat
    19741 tcaaaagtgg caaaataatt tattgagcaa atataaaaat tcttatgtaa gaaacatgta
    19801 tgggattttt cagatgtcat tagatcgagc agttgttttg ggactacttg aaaaaaatcc
    19861 tgcaaaagtt attggaaatg tgaagaaaag gaaaactaca gttgattttt ggacaaaaga
    19921 agaatttaca aaagttattt caacttttta tattgatgat ttgtaccaac attttggttt
    19981 tatttgtatg tggttacttt ttatgaccgt tatgcgtttg ggagaagcca ctgcattaac
    20041 ttggaaagat attgattttg aaaataaaaa cttgcgtgtg aataaaacac tctattataa
    20101 gagagccaaa acctatgagt ttgtagaacc cgaaacggct tctagtattc gtacaatcga
    20161 actagacgac aatacaatta cctttttaaa agcttggaag gagcgtcaag tttcaatagg
    20221 aggcatgtcg tttgtacttt cttataatgg aacacctact cagaaatata caatccgtca
    20281 tattatgaga agacatgcaa cgatcgttgg tgttcatata atccgcatac acggattaag
    20341 gcatagtcat gcttctttgc ttatatcaca ataaaaagat gcacttcgaa ttaaagaaag
    20401 gttaaaacat gctgatgtac aaacgacttt aggaacttat ggtcatttgt atctaaattc
    20461 attgagagag ataacaaatg atcccacaga ttatatccaa actaattttt ctaaaatcaa
    20521 accgacacct atttacgata ataaaaaata aatgataaac aaaagtagga tcacaccaaa
    20581 agaaacacac tagaaaaact ataatacagg cttttctagc gtgttgtttc ttatttccgc
    20641 ctatttatac attatactca taaagcattt aatgcatcga tcgtagccgc attgtctata
    20701 tgggtatata aagttgttgt attggtactt gaatgtccca attgttgggc agttaatacc
    20761 aatgaatttg tctgttggta gagtctagta gctaatgtat gacgcagttt gtgagggctg
    20821 acttgaattc taaagccttt tgaatatttt gctaccatcc gttcgattgc aataccggat
    20881 atacgcttgg cttctccttg gtaaattgct agaaataaag ctttttcgtt ttctgttact
    20941 ttatatcgtt ctttccgaat agctagataa ttagctaaat attccattgc gaatgctgct
    21001 atattgacag catctctttt atttcctttt ctagttacta ccacattatt cttatctaaa
    21061 gataggtcat ctaaattaat atttataacc tcggagagtc tcaatccaga tcctaaaatc
    21121 agtgcattga tcgccaggtc tctttctaca tctcgttgat aatagatcaa agctcgttta
    21181 ctcaaagtat ttttatattc attggcaata taatctagat aattttgtgt atccttatct
    21241 agaaataatt ttttctcaat ggcattggca cgtgcagcta acgtagtttt atctgtgatg
    21301 gttgctactt gatccatagg attattgtct aagtatggtt ttcctagagg attattggaa
    21361 cttttcgaaa gatatttaaa tagaaccttt aatgccgtga tatttctatt gatagtagaa
    21421 gtagatagac ctaagttatt attatctttg agcttagttt ttgttgtctc tttttttaca
    21481 ttttcttttg tgcgacgttt caaatgagat ttgtacaagt ttaggtcata ggcagttaac
    21541 tgtcttatcg aggtgataga agtatcagga acgatagact cactcagaag ccattcataa
    21601 aagagcttat aattttttag atattctaaa gtggttcgag gtgattgatc tttatcctca
    21661 cgatcttgaa caaaatcttt tatataatcg ggcatatgaa gtatgattgt atctattttt
    21721 tgatatattt ctgtattttt catgtcattc atcctttcaa taagtagggg agaagagtat
    21781 ctctataatt ggactatacc aattatagaa tgttttgtca attggtatgc tctaaaattt
    21841 attaatttgt ttcaaaaaaa gcatataaac aggtatacgt ttaataa
//
LOCUS       DACGDM010000038        20422 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.039, whole genome shotgun sequence.
ACCESSION   DACGDM010000038 DACGDM010000000
VERSION     DACGDM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.039"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            18..1097
                     /locus_tag="IXR05_001553"
     CDS             18..1097
                     /locus_tag="IXR05_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4260060.1"
                     /translation="MTQTHDNTVSRKGKHLSYSERCQIAILKKEGYSNRQVAKVLGRV
                     PQTINNEIDRGTITQLKRQTQNGKVYDTYYSVYDADAGQAFYEKQRLNCGRRPKWANT
                     NAFIDWADDKMLNEKWSPDVVVGFARKHELFDCAIIPGTTALYQWIDRGIMRTKNMDL
                     LEKLSRKIKAVRPGHRPNKRVLGTSIEERPKEVETRETFGHWEIDTVVGNKTKSDAVL
                     LTLAERQTRFEVILKLNGKDTESVDQAVQQLRERAGANFDQLFKTVTSDNGSEFSGLH
                     DALQDVADVYFSHPYASWERGTSENQHKLIRRFVPKGSPISEVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFKQERLVA"
     gene            complement(1294..1995)
                     /locus_tag="IXR05_001554"
                     /pseudo
     CDS             complement(1294..1995)
                     /locus_tag="IXR05_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(2009..2933)
                     /locus_tag="IXR05_001555"
                     /pseudo
     CDS             complement(2009..2933)
                     /locus_tag="IXR05_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            3050..4129
                     /locus_tag="IXR05_001556"
     CDS             3050..4129
                     /locus_tag="IXR05_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4260061.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            4161..4754
                     /locus_tag="IXR05_001557"
     CDS             4161..4754
                     /locus_tag="IXR05_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260062.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(4864..5091)
                     /locus_tag="IXR05_001558"
     CDS             complement(4864..5091)
                     /locus_tag="IXR05_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4260063.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(5194..7782)
                     /locus_tag="IXR05_001559"
     CDS             complement(5194..7782)
                     /locus_tag="IXR05_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAQ4260064.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(7802..8461)
                     /locus_tag="IXR05_001560"
     CDS             complement(7802..8461)
                     /locus_tag="IXR05_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4260065.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(8510..9013)
                     /gene="trmL"
                     /locus_tag="IXR05_001561"
     CDS             complement(8510..9013)
                     /gene="trmL"
                     /locus_tag="IXR05_001561"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAQ4260066.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(9234..10100)
                     /locus_tag="IXR05_001562"
     CDS             complement(9234..10100)
                     /locus_tag="IXR05_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4260067.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            10209..10850
                     /locus_tag="IXR05_001563"
     CDS             10209..10850
                     /locus_tag="IXR05_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAQ4260068.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(10912..12273)
                     /gene="mgtE"
                     /locus_tag="IXR05_001564"
     CDS             complement(10912..12273)
                     /gene="mgtE"
                     /locus_tag="IXR05_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAQ4260069.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(12291..13190)
                     /locus_tag="IXR05_001565"
     CDS             complement(12291..13190)
                     /locus_tag="IXR05_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4260070.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(13192..13989)
                     /locus_tag="IXR05_001566"
     CDS             complement(13192..13989)
                     /locus_tag="IXR05_001566"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAQ4260071.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(13967..14671)
                     /locus_tag="IXR05_001567"
     CDS             complement(13967..14671)
                     /locus_tag="IXR05_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAQ4260072.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            14802..15377
                     /locus_tag="IXR05_001568"
     CDS             14802..15377
                     /locus_tag="IXR05_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAQ4260073.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            15495..16172
                     /locus_tag="IXR05_001569"
     CDS             15495..16172
                     /locus_tag="IXR05_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4260074.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(16251..18059)
                     /gene="pepF"
                     /locus_tag="IXR05_001570"
     CDS             complement(16251..18059)
                     /gene="pepF"
                     /locus_tag="IXR05_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAQ4260075.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(18235..19233)
                     /locus_tag="IXR05_001571"
     CDS             complement(18235..19233)
                     /locus_tag="IXR05_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAQ4260076.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(19459..20112)
                     /locus_tag="IXR05_001572"
     CDS             complement(19459..20112)
                     /locus_tag="IXR05_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAQ4260077.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT         5910 a         4442 c         3640 g         6430 t
ORIGIN      
        1 gacaaggatg aattcacatg acgcaaaccc atgataacac agtttcacgc aagggaaaac
       61 atctttccta ctcagaacgt tgccaaatcg ctatcctgaa aaaggaaggc tattccaacc
      121 gtcaggttgc caaagtgctg ggacgtgttc cgcaaaccat aaacaatgag attgatcgcg
      181 gaaccatcac ccagttaaaa cgccaaacgc aaaatggaaa agtgtatgac acctactatt
      241 ctgtttatga cgctgatgca ggacaggcct tctatgaaaa gcaacgactg aactgtggca
      301 gacgccccaa atgggcgaac acaaatgcct tcattgattg ggcagatgac aaaatgttaa
      361 atgaaaaatg gtcgccggac gtcgtggtcg gatttgccag aaaacacgag ctgttcgatt
      421 gtgccatcat tcctggcaca accgctcttt atcaatggat tgaccgcgga atcatgcgaa
      481 caaagaacat ggacttgctt gaaaaactgt cccgtaaaat caaagcggtc cgcccaggac
      541 accgtcccaa caagcgtgtt ctcgggacgt caattgaaga acgccctaaa gaagttgaaa
      601 cacgggaaac gttcggtcat tgggaaatcg acacggtagt gggaaacaag accaagtcgg
      661 atgccgtgct gctgacgctg gctgaacggc agacacgctt tgaagtcatc ctaaagttga
      721 acgggaagga caccgaatcg gtggaccaag cggttcaaca gctaagagaa cgggctggcg
      781 ctaacttcga tcaattattt aagaccgtta catccgacaa tggctcggag ttttctgggc
      841 tacacgatgc tctgcaagat gtagctgacg tctatttcag ccacccctat gcttcttggg
      901 agcgtgggac gagcgaaaac cagcacaaat taattcgccg tttcgtcccc aagggaagcc
      961 cgattagtga ggtgagcgag aaccagattt tgcggatcca gcgttggatg aacgattacc
     1021 cgcggaaaat tttgggttat gcgacaccac atgatacatt cgtccaggca ttcaagcaag
     1081 aacggttggt ggcttgaccc attattcctt gataacgatc ctcactcggg acatggcttc
     1141 atgtctggaa agctggcctg gggccagaat cgtctgaaga ctatcatacc tcagttcatt
     1201 atcaaggcct cactgattta gaataacgag gcagttacgg tatcaaacaa atgagttacc
     1261 tgtagtggct aacttaaact tgaaatttac ggacgtaaag cttgctgcca aattagcgat
     1321 tgaaactaac gattgctttc taggaatcaa ggacaagcga ataccatttg acgattgatt
     1381 tgcttgctga tcctgtacat tgcggacccc ccacatcgtc ccgtagagaa tcgccattcc
     1441 aatcagagtg aagaaataaa aacttttgaa actcatatta cgacctgcat gaacttcttg
     1501 aaaagatact tcttgttcaa aaacagtcat gatgggcgcg agatcaacgt tctccacttc
     1561 tgccacttta ctcgaaatta taccaatacg ctgtaaaaat tgatccatga cgtttttcat
     1621 caacgtctga ctcattcctg cttgacccac atggagcgaa acagatgaac catcaatgag
     1681 ataaaaacca gccaaatcat ctgcatttag cttttcattc gcttctactt ccgatagttc
     1741 ctgtacttca aataatggtt tatcattgac ttcgacttgt tctaagactg tggtaaaatt
     1801 ttccgaaagc gctgtttgat ccgctttgat tacaattcca gtattaatcg tttcgagatt
     1861 gccaccttga tcaatctcgc caaaggccgc cataaacatc aatcctaaaa gaattggaaa
     1921 ggccaatgtc caaaacaaca tggatttatt tcgcagcagt atttttgtgc gatatttata
     1981 aaaatgccaa aacattattt cccctcctct agtctctcaa atccttgcca gtaatctcta
     2041 aaaagacatc attcaaggac gcttctttgg ttgctatttt tccgtaactg atcttttctt
     2101 cttgtaagat tgtaagaatc ggcaacaata ctgtatttag ttcagtagtt gttacttgga
     2161 gctgaccttt tttataagcg attccatcag aagctattgt tcgctgacaa cacgttttct
     2221 gggagtaatg ggatgtcgat cgtcaaacga tccgccgtcc gtaccatatc ttttagagat
     2281 tctttggttc ctttagcaat cacctgtcct tgatccatga tcacgatctg gtcgcaaaga
     2341 atttctactt cttccatgta atgtgttgta tagacaatgg ttgctccttg tcgattcagc
     2401 tccttgatac tttctaaaat tttattccga ctttgggggt ctacagctac tgtcggctca
     2461 tctaaaaaaa ttaaccgcgg cttgtgggca atcccacatg cgatgttcaa ccgacgtttc
     2521 aagccaccac taagttctcc tggacgaaac gaaacatatt tttctaatcc cactaattga
     2581 atcacctctt caatcaaggc tttccttttc tctttttcgg aaacatataa accgcaaaaa
     2641 taatcgatat tttcttgcac acttagttcg tcaaagaccg caacgtcttg aggaacgacc
     2701 ccaatcattg ccttgacagc ataattttca ggagtcattg ttgtcccgaa caatttaatg
     2761 gttcctttgt cataatttaa caaagaaagc atacagttga tggcagtcga tttcccactg
     2821 ccgtttggtc ctaacagacc taagacttct ccttcttgta cttgcagatc aaaatgattc
     2881 aatgctacaa aatctccata gcgtttgact aatttatcaa tttcgataat catcatgaaa
     2941 aactccttcc aaatttcttg ttgatctgac tataataaag tgcaagaaaa gaaactagtg
     3001 acgattggct aaaccacaca tgacatttgt cacaatgaag gagtctgcta tgcataaatc
     3061 tcggctactc aacgaaacta gctttctact ggttatctca ttgcttttgc tggtaagtca
     3121 aggattcgtt gctatgcaag ttatctattt attgatcgcc gttttattca ctggtgtcag
     3181 ttatttactg cctacaaagc caaattggat tttccaagtt attctatttc ttttatgtgc
     3241 ctttttacct gatcttgtcc tgtttctgcc agcgacgatg cgagtgatcg cccctgaaga
     3301 aagccacctt gattacttgt ttttgttagg ttttttgttg atttcgacgg ttggtaatca
     3361 tccccccatc aaggtcgcct ttgtcgtaat tttgctgttt ttttcctttt acttacgaaa
     3421 aaaagatcaa cgaacgaccg atcttgagaa aaagtacatt gtctccaaag atactcattg
     3481 ggaaaaacaa caagagttat cggaacaaaa taaagcattg gccctgtcac aagaaacaca
     3541 attagccttg caaattgtgg aagaacggaa ccgaattgcc cgagacatcc atgacaatgt
     3601 cggtcatctg ctgtcaagtg cgattttaca aattggtgcg cttgaaatga tcaatcaaga
     3661 accaaaacta aaagaaccat tagaaaattt aagtgccacc gttcacactg ggatggatcg
     3721 gattcgtcaa agtgtccatg acctccatga gacatcgatc tcttttcaac actccttaga
     3781 gtttctgatc gctgattttc cttcttctgt tacgattgaa ggaaacttgt ttgaaggatt
     3841 gaatgaaacg cagcaaaact gcttcttaat ggtcatcaaa gaagccttaa ccaacagtat
     3901 caaacatagt catgccaaaa ccgttgtttt acattttcga acgttgccgg ccttttatcg
     3961 cttgcaaatc acgaatgatg gcaccagccc acaaaaaaat tctgctcccg gtattggttt
     4021 gaaaacgatg cgtcaacgtg ttcaagaaca aaagggacaa gtccatattt tccaagaaaa
     4081 ccagcaattt cagttaacga tcattttacc aagggaggga caccaatgat aacagtagtc
     4141 attattgaga tgatccattt gtgacgaaat cgttacaaac cattttagaa agcacgaaag
     4201 agatccgtgt gttaggcatt ggtcattgtg ccaaggatgc gctagtctta tacgaaaccc
     4261 atcgtcccga tgttttgctg acggacatcc gcatgcctaa acaaacgggc atcgatgctg
     4321 ccaaagaaat tttggctaaa tttcccaaag ccatcctttt gcttttgacg acattcaaag
     4381 atgaagaata catccgcgaa gcattttcca tcggtgtcaa agggtattta atcaaacaga
     4441 acttgcaagc gattattcct tctgtcaaat ccgcttataa tggacaggcc gtatttggta
     4501 atgaaatcat cgagactttc actcaaatga tgaagaataa accgacgatt gatagtcatg
     4561 cttatgcttc ttttagtgaa cgtgagcttg caatcatcaa agaagtagct gccgggaaaa
     4621 acaataaaga aattgcagat gccttgtact tgagtgacgg cactgttcgc aattacatca
     4681 gccaattact agaaaagcta gatttacggg atcgcacgca attggctatc tatttttatc
     4741 agcatttgca ataagtctta tctaacacaa aaaaacctga atgatgctcc ttcgcatcat
     4801 tcaggttttt ttcacatctt ctattcaatt gtcccgcaaa ccatttcctc acgattgaaa
     4861 gaatcaagga ttcgcagggc tgccaggatt cgttggattg ttcggcgtgt taggcggaaa
     4921 aataggcgcc ttgtctaacg ttttttctag ttttgattct tcacgatcgt ctcgttctac
     4981 atcaggactt tcattcaatt tgaattcttt ttccatctca tctaactttt taaagtcatt
     5041 gccagattct tttgctaatt tcgctaattt atcttcggtt tctttagcca taaagtaacg
     5101 cccccctttt gatttcagct tagcatatca cactgaaaaa acaaaagaaa acgctaacca
     5161 acgatcattt ttagctattt ctcatcttta aaatcaagca ttttttgccg gtataaaatc
     5221 gtagggagaa ctgttttcca taccaatcat cggatctact aactggttat cgatcacttc
     5281 tgctgtaaga acgaaatctt tagaaacagc aggttctacc tcttctttct tttcttctcc
     5341 aacaaatgaa gaaaacagat ctggttccac tgtttccatt acttggtttt tcgtttcatt
     5401 cgtcccactg tcatcttcta caggtagctt ttcttttaca acccgtggct cttttgtata
     5461 gttcccatct tcaaatggat catttccgac caaagaatct tcataagctg ctagtttggt
     5521 ccggagagtg atattcattt tatcattatc catgatcctt gatttcaacg tagtcatccg
     5581 gcttgctgat tcattcgcta cacaagtgac ataggcttgc tcttccccta acaaaatcaa
     5641 cagttcctta ctgcgagtca ctgccgtgta gagcaaatta cgctgaagca tccgctgata
     5701 ttgatggacc atgggcaaaa taaccatctt gaattcactg ccttgtgatt tatggattga
     5761 gcaacaataa gaaagagtga ttttattcca ttcgtttctt ttataagtga cctcatttgc
     5821 atcaaactgg ataactaatt catccacttt atcttcagaa tcttttgcca agatgatacc
     5881 cgtgatttct cccatatctc cattgaatac attcaattcg ggagtattga ctaattggag
     5941 gactttgtct cctatccgat aaacggtgtc gttccaatgt acttcctttt ttccaggttt
     6001 ccctggattg aatatctcct gcatcatttt atttaacgca tcgatccctg caggtccccg
     6061 atacattggt gctaatactt ggatatcttg tgcacggaat cccttatttt tcgctttttc
     6121 cacaatttta gagatcaagg gttcaatttg ataagcatca cttcggaaat aggaacgatc
     6181 tttttgattc tttgtgaaat cttttggcag acgtccttct ttgatctcat gggcaagagg
     6241 aataatacta gaaccatcac cttgccgata aatctgattg agttccattt tgggaatttg
     6301 ttcgatttcc aaaagatcat ggagtacttg accaggaccg acagagggaa gctgatcttt
     6361 gtctcctact aagataactt gcatattcgt cggaatcgct ttgaataatg tgttagccag
     6421 ccatgtatcg accatagaca tctcatcaac aatcaaaagt ccgccttcta attctttcgt
     6481 actgactgaa ggtgtttttt cccgtccatt cagccccaga agacgatgga tcgtactggc
     6541 aggcagacct gtcgtttcgt tcattcgttt agctgctcgg ccagttggtg ctgcaagtag
     6601 aataggaaaa atttcttggg tatattttga aggatccaat tccagtccgt tcaactctgc
     6661 aaaaagattg acgattccgt tgatcacagt agttttcccc gtacctggtc ctcctgttaa
     6721 aataaataga ggggaacgga ttgcttcagc gatagcttgt tcttgcgaag gtccatactg
     6781 tatgccgaat attttttcga tacgccgaat attcttctgc acttcttttt caggataatg
     6841 gatttctttt ttacgactga gaaggcgctg gatcgaatta ccgatccccc attcagaaaa
     6901 gtacaaactg ttttcgtaaa gattagtctc ttcttgttgt atctttcctt cttcaacaag
     6961 ttggataatt acagtagcaa cctgatcagg ctggatttca attgggcgac ttgtttctaa
     7021 aatacggatc gtttgctgaa gcaatgtctc cgccggtacg tatgtatctc ctgtttgaac
     7081 tgcatgctga aaaatctgat gcaagatagc tgctcgaatt cttctcggtg aatctgctgc
     7141 aataccgatt tgttcggcta gattatctgc acgtttgaac ccgattcctt ctatgtcttc
     7201 gactagctgg tacggatttt cttcgatgat atccaaagac tcgttcttat aggcctggta
     7261 gatactgaaa gctaactgac taccgaaccc gtaacgattc agtcccatga tcacttgatc
     7321 catcccgtgg tttagccgaa tcgtctcagc aagcatttct ctttttggct tcgtcaaacc
     7381 ggagatttgt tttaataccg aaggatcagc aatgattttt tcgatagcat cttctcccag
     7441 caattctaca attttttctg ctgttttctt cccgattcct gggaattttt cgctggaaag
     7501 atacgctacg atcccatttg cagttgttgg cttttcttgc tcatatcttt cgagtttaag
     7561 ctgccttccg tatttaggat gatccactaa ttctccataa aaacgataag tctcattttc
     7621 ttgaatatcg ccgaaacttc cggtgactac aatctctttt tcacggtaat cagctgtggt
     7681 ttcactgatg tgtaccaaaa gcactttgta aaaattacta ggattttgaa aaaaaatcgc
     7741 ggcaactgta ccaacgaaat aaggcatttc ttctggctgc atcggaagcc gcctccttct
     7801 tctatagtaa aggttctggt gctgtttcag ttcctaaaaa atctgtttgg ttccatactt
     7861 tcagttcata tggcaataat ctgcaaggct cttcagtctc taaaatcgtc aaactactat
     7921 tgaacaatcc acccatttca cgcaactcac ttagctcttt tcctgtcatc cattgaatgg
     7981 ctgcagttaa agaagctcca tgtcctacga ataaaagtgg gccatcttta tgttgggcaa
     8041 ccgcatctgc tacaacagtt tcgatacgtg tgattgccga ttcaatcgtt tctccgtgaa
     8101 aaggagaagg atcatacaga tctaaatgat tacgcaaatt cggcagatta tccggatatt
     8161 tctggtacat ttcatcgatc gactgacctt ctaaagtacc cagccctagt tctcttagct
     8221 tatctgtata aaaaatctct accggacgag caagctcttt gttgatacct tctgctgtat
     8281 cacgtgctcg ctttgctgta ctggaataaa ttgctttaaa aggaacatat tttacctttt
     8341 tcccaaatgc tttgatttct tcgtaacttt gtggcaaaag cggagaatcg ccattgctcc
     8401 cttgaaaacg tctttcctga ttccattgtg tcttcccatg tcgggtaaaa tatagttcca
     8461 tacgcagcaa actcctgtct ttcttttatt ttactctata ataaactgtc taatccagct
     8521 tgtcattttc atagtgatgc gtcaattcta aattagggaa tccttgctgg cgaagtgctt
     8581 catacactat cattgcagct gtattcgata aattcaatga gcggacatgc tcatcattca
     8641 tagggatgcg taaacacttt tcttcgtttt cacgcataaa tgtttctggc aaaccggttg
     8701 tttcttttcc aaataaaaag aagtgctctt ctccatcagc aaaattttcg tcactatata
     8761 ctttatgggc aaattttgag atcaaatgta gtttacgatt acctaaaaat gttaaaaaag
     8821 cttctaaatt actgtggtaa gtaatattta catcattcca ataatccaac cctgcccgtt
     8881 ttagatgttt gtcatcagtt gaaaaaccta gtggctcgat taaatgaagc ggagtattcg
     8941 tggctgcaca cgtacgggca atatttccag tgtttgcagg gattaatggt tcaaataaaa
     9001 cgatatgatt catcaggatc attcctctca tatttatgtt cgtttctatt ttctgacaat
     9061 ttgatttttg cataaaaaaa aacgtatcaa ctcggtgtca gtcactgcga gtcgttacgt
     9121 tagtgaagct cttctcacta acttttatca gaacaggaac ctgataaaaa ccaatgaaaa
     9181 aacaacttgt tgctaatata acaccctcaa cttttttttg caacctctac tcattaaaaa
     9241 ctgctagaaa aacgttttct cttagttcct tttaataatt ctatgtcaat tgtaatcttc
     9301 ttcaaaggat tcttatataa gtctgctttg attcgctctt ctacctgcca ttctaaaggt
     9361 gacatggcca aaagatcttt ttgattttcc tctggtatct caaattcata ggttacacgc
     9421 tgacgttcag ttaatttcat tgcttcagca aacttggcta ctacacgttc attggaataa
     9481 ctctgttttt caggttgatt cggataaaaa gcctgacgta gttcctttaa ataattttct
     9541 tgtggcacca ccttcaacac ttctccatct tctgagagta cacgttggaa ttcttggtaa
     9601 tgagaaggcg aaaagatatt taaaaccgcg ttgaatgttt gatcagcaaa cggcaaattg
     9661 gtcaaatcag ctacacacca aaatgcttcg gcagattgtt ctgtagctgc gtagactcct
     9721 tcttttgaaa tatcaaatcc aacagcattt tgaatctttt tcaattttga aagttcattc
     9781 aagaagctac cttctccgca gccaacatct aatagcgaga cttcttcagg taaatgctgc
     9841 gcaatagtct caataacggg ctgatacatg ccagattgga tcattctacg ccttggaacg
     9901 aacattcctt gatcgtattc tgttttaacc gcatgggata aaaaataaag tgttcctttt
     9961 ttggaaaggt caaaacggtg attatttttg catatcaagc cattatcaga cttttttact
    10021 tcttcttggc aaaccggaca gcggaacagc tgatgatttt ctgccaaaaa ctggcgtcct
    10081 cggtcaattt tttttaacat agttccccct catttctgtt ttatcttacc gttagatgct
    10141 cactttggca actgctaaaa atatgataca atgcctagaa gaaagtgaaa gataaaggag
    10201 aagattagat gatcaaagaa ttttgcgctg aaaactacac atctattcct ctagcaattg
    10261 ctagaggagc cgatcggatc gaattgtgtg acaacttagc ggtcggtggc acaaccccga
    10321 gtactggtgt gatcgaagaa acgttaagtt atgctgggga aaaagatatc cccgtaatga
    10381 cgattattcg tcctagaggg ggcgacttcg tctataacga tatcgaattg aaaatcatgc
    10441 atactgattt gattgaagca aagaaattag ggacggatgg cgtagtattt ggttgtctta
    10501 ctccttcagg ctggctagac gaagaggcct tagaactatt gatcgaaaca gcagaagggt
    10561 tgcagatcac cttccatatg gcttttgaca gtattcctga agatcggcaa ttcgaagcaa
    10621 tcgattggct ggtagaacat ggtgttgacc gtatcttgac tcatggcggt cctgctgaca
    10681 aaactattgt agaaaatttc ccacggctta aagaattgat tgcctataca gatggccgct
    10741 taatcatttt gcctggtggt ggtgtcactg cagagaatgc agcacatgta gctaaagaat
    10801 tgaacgtaag cgaagtacac ggaaccaaaa tcgtggatct tcagttataa tcttataaac
    10861 aaaaaaacat ttgcaacagg cataatgctt attgcaaatg tttttgtttt tttacataaa
    10921 atagcccata aataaagaag caatattgaa ataaatcagt acactcgtca aatcgctcaa
    10981 agtcgtgata aagggaccgc ttgctactgc tggatcaaat cctagacgat ccattagcat
    11041 cgggattaaa ctacctgcaa gattcgccac tgtgattgca aatagcatag ccatccctat
    11101 gacaaacccc aagataaaat tatgtttcca aaaacctacg attagaaaaa tcgtgatccc
    11161 cgtaacagct cctgtgacaa cgccggtcaa gacttcagcc aaaacaagtc gaacaaatcc
    11221 atgatctttc tcatcagaaa tcgcaagtcg acgaacagcc acagctagcg actgggttcc
    11281 agcattaccg gcagttcctg taatcagcga aatgaagact gctaaaatac tcgcttcact
    11341 taccaagtct tcatagtgac tgattaaaga agcggtcgac atacccaaaa acaacagagt
    11401 gatcagccaa ggcaaacgtc gagacgctgc ctttactgga ttttcattaa tttcttccac
    11461 attgaccccg gcaagtcctg aataatcgct agcagcttca tcatcaataa cgtcgatgat
    11521 atcatcgact gtgacgattc ctaacaaatg atcatcataa tcggtaacag gaagagctaa
    11581 gaagtcataa tctctaaatg tttgtgccac atcttcttgg tcgtcgccta catgaactga
    11641 aagcactcgt tcgctcatca gatcagaaat cattgcgtcg tcatcattca cgattaggtc
    11701 gcgcagagaa ataaccccta ctagctgacc ttcttgatta acgacataga tgtaatagat
    11761 tgtttcagct acatctgctt cgttcttcag cacgtacatc gcagagcgaa cagtttgatt
    11821 ggctacgatc gaaacaaatt cagttgtcat gatcgcgcca gccgtttcat cctcgtaatg
    11881 gagaagttcc ttgatttcac tggcatcgtc tgccgacatc aaacttaaat atttagcaat
    11941 ttgcttttta tccagcgtat taagcaagtc aacagcatta tctgtataca tctcagaaag
    12001 catatcagct gcatagctag gacgcatttc atctaggtat tctttcatat gttcgttgtc
    12061 ttcttcaatc acatcgaaca tatccgctaa ttctttaggc gacagatagg aatagatcag
    12121 ctgcctgttc tcttctgtaa gagattggta gaattgcccc tgctcataga tatgcatctc
    12181 taaaaaactg tttctgaatg cctgaatatt attttccctt aaatcttgag tcaactgggc
    12241 aaatctttcc tctaattctt gattttcatc caaaccaatc tcacctcgcc ttattcttca
    12301 aaccgtctca caactgcctc catgtctgcg gctaaaggct gcttgaactc cagcaactct
    12361 tctgtaaatg gatggtaaaa acgcagatca taacaatgaa gggcttgtct ttttattccc
    12421 agatccattc gcccgccata catatcatca ccgagcaggg cacagccaat tgcggaaaaa
    12481 tgaactctta tttgatgtgt ccttcctgta tgcagctgga tatcaactaa cgcgatttct
    12541 gttagtcgct tctctatcca gtactcagtc tgtgccgaac gtccttcatc agagaccatt
    12601 cgcttcaata gcgaagaata atctcgggcg atcggcaaat cgatatgtcc atgtgccgat
    12661 aaatctgaaa gccttccact gactaaggcc tgatattttt tcacaaactt cttttcacga
    12721 agttgcatat ctaattttgc gtgcgcaaat ccatgctttg caaaaagcat caaaccagat
    12781 gtatcccgat ctagtcgcgt caccacatgg attacttggt tttcgtaacc ttgtttttta
    12841 taataagcct ttacacgatt agccattgtc ccatttggat ggtattgggc aggaatagac
    12901 gaaacgcctg ctggtttatt tactaccaga acgtgttcat cttcatacac gatatcgatc
    12961 ggtgtttcat ccaaaagtac ggtttcatgt tctccttcag caggaatcac aatggttacc
    13021 ttatcatcct tagctagaga aaacaagaca ttttctactt gatcattaac tttgatttga
    13081 ccgccttgaa attttatttt cgctaacaga ccctttgaga tccctttttc ttttaaaaaa
    13141 tattttactt gctgagaatg atctttctca taatcccatg taaactgcat atcaatcctc
    13201 actaataaag gcatctttca cacgatgcca aaaatgcata tgtcgataag aagcaaaatg
    13261 gatccgttct tctgctattc gataataaat tgagcggata tttgcttttg cgacattcaa
    13321 ttgatcaacc gttacaagat aatcttctgt attttccaat tttatttcta gccattcatc
    13381 atgggcaatc acgatcggag aacccaaagt acgaaacact cgattattca gtgaagcaat
    13441 ctctgccaac tgaaaggcat tgatactagg atggatcaca gcaccgccga cacttttatt
    13501 atatgctgtc gaaccagtag gcgtagaaat cgtcaatcca tctcctctaa aactttcaaa
    13561 cagctcgttt ttgatgtata catcggctac catcgtacga ttggcccgtt taatcgttga
    13621 ttcattcagt gctaaaaaat gctggtccgg tgtttcatcc aaataactga tccgaacatc
    13681 cagcaaggga taactaacac tttgttcccg gttcgttcgt aagctgtcta ctagttcttc
    13741 cagctcgtaa tcccgccaat ccgtgtaaaa ccctaaatga cctgtatgca cgcccaagaa
    13801 acgcacatca ttcagacaat gactgtagtg atggaacgcc gacaataatg tgccgtctcc
    13861 gccgactgag atgaccaatt ctggctcatg atcatctcgt tgaatccctg cttgttctaa
    13921 aagtgcgttc aaacgttctg tcacttctat agtctttgct tctttattat gaacgatcgc
    13981 tactttcatc ccctgcctcc tctctttcgc tttctttctt caaaagcgtt cgatagtaga
    14041 catcatctga ttttcctctt ccatgggaga ataaccgctg tgcttcttgg atttcttcac
    14101 ggatactgga catctcttca tccaactgat aggcagcttc tgccgcacgc tgaagtcgtt
    14161 cactcatttc ttctggaaaa acgccttgat atttataatt cagcgaatgc tcaatcgttg
    14221 cccagaaatt catcgcaaga gtccgaatct ggatttccgc caaaattttc ttctcaccgc
    14281 tgatcagctg tacaggatac tcgatcacca gatgataaga acggtagcca cttgcttttt
    14341 tatttgtgat gtaatctcgt tcttggagaa ctttcatgtc ttttctttta cggatgatct
    14401 caacaacttg atggatatct tctacaaact gacacatgat ccttaacccg gcaatatcag
    14461 acatttcttc ttctaaacgt cccattggaa tatgccgtaa ttgtgatttt gttacaatac
    14521 tatcgactgg cttgactctc ccagtgacaa attcaatcgg gacatgtcga ttttgttcac
    14581 ggaactgttt gcggatcccc cgcagtttca ctttcaattc tgatacagtt tgttcatatg
    14641 gtgctaaaaa tgcttcccaa tctcgttcca tagctgatac ctctacttca ttaacattca
    14701 ttgtttattc taccatatat gcaaagtttt ttcgtactct tgatttatgc attgaccaaa
    14761 aaaagaaaat taggcaaaat agacaaaaag gagtcgatca aatgacacaa atgcttgaaa
    14821 tcgaatataa atctatgctg acaaagcaag agtacgagat attcatcgct cactatcaat
    14881 taacagataa agatttccgt gtacagacta atatttattt cgataccgtt gatgaacagc
    14941 tgaagaaaca aaattgtggc ctacggatcc gtttcgttgg tcatcaagct gaatatacat
    15001 taaaaacacc tgctgaaaaa gggcgtctcg aaacaacgga tacctttata acagaagaag
    15061 cagaagcatt tatcttcgaa aaacgtctgc ctcgttcagg cgcagttttt caaaaacttt
    15121 ctgatttgaa tatcgatcct gcttcattaa tccaaaccgg aaagcttaca acaaaacggg
    15181 ctgaattccc tattgaagaa ggacttttag ctattgatga aagctgggga gacaatctac
    15241 acgattttga actggaacta gaggtagggg atgcatctgt gggaaaaatt gcttttataa
    15301 attttttaaa acgtttttct ttaccttatc gtcctgctaa gaacaagatc caacgtatgc
    15361 ttgaagctaa aaattagaaa cctttcattt tcacaaggca cttgagttca tttttttact
    15421 tttttctgtt aagttatagg atgtgaaaga atctagtcac tagttgtata gaatctattt
    15481 tgggggagat tcatatgatc gaaatctatt tatttgttaa tcctttaggg gaatactgtt
    15541 tcgaaatgga acaacagtta ttacaattta tcgaagaaga gtacgggaca ccatcaaaag
    15601 aaaagatgca atttcgcttt cttcctttgg tcaatttgca gacaattggg gatgtcatgc
    15661 aacaaaaagg aatttctcag aacaatcttg aggaacgtaa tcacttattc tcaatgactt
    15721 attctgcagc attggactgc aaagcggcgc agtttcaagg aaagaaaaaa ggccgccgtt
    15781 ttttgatcaa attgcaagaa gcagtcggct gtaatgacat accatattct caagaacttg
    15841 ctgaatccat atttgaagaa atcggcggcg atttgaatat gtttaaagaa gatcgtcagt
    15901 ctgacttcgt taaagaagta ttcttttctg atcaaaaaat tgctcgggaa atgggcatca
    15961 caaaacaccc ttctgcagtc gtttacaatt atgcctgcga ccgtgatttt ggtgttttag
    16021 tagaagtaaa aggtacaagt agcctttgga gaatcacaga gctgtgtaaa acaacagata
    16081 actcatatca agtttttaat ggtgaacatt tacatacaaa tgattctcag ttccattcaa
    16141 gaactagcca tttacacttg ctttctaatt aaaaaaatac gtcgactccc ttacaagaga
    16201 gccgacgtat ttttttcgtt tctattcgag aaaatcaaaa atagaaagcc ttataaacga
    16261 tcgatcaatt cttctaattc atttagacgt tgttcaaaca tcgacattgc atcttcaata
    16321 tatgcagcct gtgtcatatc aactcctgct tttttcatta cttccacagg ataatcgctg
    16381 ttacctgctt ttaggtaagc caagtagttc tctagtgcct ctggttcctg gtttagtatt
    16441 ttcttcgcca gtgctgaagc agcagaaaag ccagtcgagt attggaaaac atagtaatta
    16501 taataaaaat gcggtatccg tgaccattcg aatttaattt ctgggtcttc ttcgactgct
    16561 ggaccataat attttgcatt caatttacca taactatcac ttaggtattc actagtcaat
    16621 ggcacacctt tttcatcttc cgtatgcatg aaatgctcga attcagcgaa ttgtgtctgg
    16681 cggaaaactg ttcctttaaa cccatccaag taatggttga gtacataagc ccgtacacga
    16741 gggtcttttt ctgtttccaa taaatactcc gttaggatat tttcattcgt tgtcgaagca
    16801 atttctgcta aaaagatgga gtagtcgccg tacacataag gctggttcga acgagtgaaa
    16861 taactatgaa cactatgtcc catttcgtgg acaagcgtaa atagctgatc cagcgtatca
    16921 tgccaattca ataaaatata tggatttgtg tcatagcttc ccgaagaata agcaccgctt
    16981 cgtttccctt tattttcgac aacatcgatc caacgttcag agaatgcttt ttctacgatg
    17041 gccatgtatt cttcacccat tggtttcagt gcttctaaag ctttttcttt tgcttcttcg
    17101 tacgtaaagg taattggagc ttcccctaag accggtgtat aaagatcata catgtgcagt
    17161 ttttccactt ctaataaacg tttccgtaat tccatgtatc gatgtaacaa aggcaaatgc
    17221 ttgtttacca cgtctaccaa agtatcgtat acactttcag gaatatgatt attgctcaaa
    17281 gacgcttctc tggcagagct gtaattacgg actttcgctt taaaattatg tccttttata
    17341 tgtgtgccta aagtagaagc aaatgtattt ctaaattgtt cgtaaacact gtacaatccc
    17401 ttaaatgctg cttcgcgcac ccttcgatcc gtgctttcta gcaactgacc atacacgcca
    17461 tgagataatt ggactatttc accattttct ccttcaatcg ttggaaaaac tagatctgca
    17521 ttattcaaaa cagcaaatgt atcacttgaa gcatcaaaga tttcacctgc tccagcaaga
    17581 agagattcct gctcagcaga taagacatgg gctcgattat ctactatttg ctggatataa
    17641 tggcgataga cttccaattt tggttcttct ttgaaatatt gccaaatctg gtcatctgac
    17701 aattgcaata tttctggttc aaaccaggaa acggcttcac taactttcga aaacagactg
    17761 cttgctcttg cataaagcgc ttggtaatct gtatttccag tgtcttgatc gtttttaagg
    17821 tgcgcatata cataaatgac ttcagtttgg cgataaaccc tcaatacgaa ttcaatcgca
    17881 tttaaaaatt gagaagcgcc ttgatcaagt gttcctttgt gtttttcaga ttgttttaac
    17941 tcttctgata attccaaata tttctcatca aactcttggt cgcttgaaaa gatcttggtc
    18001 aagtcccaag ttaaattttc aggcaattct tctcgttttg gcaactgctt tacttccatg
    18061 aaatccactc cttttcttcc cttagctcta tctatcaaaa tagatcatag tctaacatcc
    18121 acatgtcaca gcatctaact tttctactca ttcatgtgtc tgcttccatc aattttagca
    18181 taactaaatc ttgttttaca tagaaaaccg attcctagcc tatttttata cttactattt
    18241 tttcaaagaa gacaagtgta tgcattcgtt aaaaaactgc tgatagacca tctcttcatc
    18301 aatcatagga aaaagccatt cccttttatg ttcttttatt tggcaaagcc atgagttgaa
    18361 atcaggaact ttctggtttt ccaaggcttc ttcgtacaac attcgataaa gaaaaacctg
    18421 ttcttgtaaa taaaagaaaa accgactttt ttgatagatc cacgatgata gatgcaaaag
    18481 atgtttatga cgcaagtagc attgttcttg tatggatact gtattctttt gcttgtgaat
    18541 aagttggcgt gtcagccatt tcttcccatc ttcactcact ttttctattt ttttcatttg
    18601 gttcatttta atttcgttac tagtgaatat ttctttaagg tccctactag aaaaagtcca
    18661 gcagctactg caaaaggaaa tatgccctga tacagtctct gtaatatgat gatacaaata
    18721 aagcttttgt ttcttgagat cagctttcca gcaatgcact cctctttttc tattatagta
    18781 gcagcaactt ttttctatca atgagaattg cgattgtcca agaaaagaat taccaagtat
    18841 ccaccatact tggtaactgt tattcaaata attttgggtt ctttcaataa atctctggtg
    18901 agacagtcta gaacattgga tttctattgc tagattcgcc aacaaaatat ccggcctttg
    18961 ccgcaacctc ggcaaatagg cttccaaaaa tactggttct actgactgtc ccagccaatc
    19021 catgaagcat tcctttaact gtaagtgctc ttttgattct ctttcactaa agaccgaaca
    19081 gttatctgat ttttgatggg caaaatgagc acattttttc tttccctttt tcaaaatcac
    19141 tctttttcga cagccacgac aataatattt ctttcctttt tctgcatgtt tagcaaaaca
    19201 gcacttatta tattcattca ttgcaagcag catttttctc cctctgaact tatttacgtc
    19261 taagaattta tttacacgaa aaaagagggc gtgaaaaagc tattctgcat caagtaataa
    19321 gaacagctaa acaaaaatag ttcccaatat ttttcgtttg gttgggcttg ttaccgcaga
    19381 tgcaagcttt tgaacacatt tatacgaaaa aaagactgcg acacaatttt tgtcacagtc
    19441 tcttactata atgctgattt atacaaaata aaatttcgtt cgctcgatag cattacgcgc
    19501 catcagacat tgtccatatt cattcaatgt ttctggtgta cgatcgctct tttcagcaaa
    19561 ctccaaaatt cgagcaatct gattctctac atccgcttgg ttgagatttt ccatccagaa
    19621 gtgaacgact aggtaatagc gctcttcgaa taaatacaaa tcagtccaag cagactctag
    19681 ttcgacatct gttgcaagtt ggatcacttg ttcaaaatct tcaaaagcaa aagttgcttg
    19741 tctttcctgt tcttctaggg cgcttccaga taattcttcc tccggatcgc tgccaataat
    19801 ctgctgacga agaaagtcac tcacatcttc tgaatcaaca gtagaatctt ctgattgaga
    19861 aatttcttca tccggaagat ttttactgat aaacagttct aatccgtctc cttttggcaa
    19921 aacttggaaa gtgacagctt cgcttcctcg gaactcctct tcgatatcaa cttcttccaa
    19981 aatactataa aagaaatttt cgatttcttt gtgattgcca agtaaatcca aaaatgaaac
    20041 gccccgttcc tctaaatctt catgaccaat tagtacacgg atcgtatttt cattaatatg
    20101 ttccatttcc attttgctac acctcacttt gccacaatgt ttaatataga ttcattgtag
    20161 cgaaatcagc ttaaatgtaa agaaaaaaaa tctcgctgtt aagcgaattt aataaaacca
    20221 gcggattttt caacctttca agctatctta tttaactata acatttttgg cagacgaata
    20281 ctatatagcc gacttttcag ctaattttcc ctctctattt ttcgtgcaat catcatcttc
    20341 tactaccttt ttatacatct aatcaagaat actttttgta aaaacaaaaa aacttggaaa
    20401 aactatcttt gtaatagtct tt
//
LOCUS       DACGDM010000039        20218 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.040, whole genome shotgun sequence.
ACCESSION   DACGDM010000039 DACGDM010000000
VERSION     DACGDM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.040"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            139..1542
                     /locus_tag="IXR05_001573"
     CDS             139..1542
                     /locus_tag="IXR05_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4260078.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            1542..2975
                     /gene="ascB"
                     /locus_tag="IXR05_001574"
     CDS             1542..2975
                     /gene="ascB"
                     /locus_tag="IXR05_001574"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4260079.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            3120..4046
                     /gene="trxB"
                     /locus_tag="IXR05_001575"
     CDS             3120..4046
                     /gene="trxB"
                     /locus_tag="IXR05_001575"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAQ4260080.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            4260..5987
                     /locus_tag="IXR05_001576"
     CDS             4260..5987
                     /locus_tag="IXR05_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAQ4260081.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            6059..6352
                     /locus_tag="IXR05_001577"
     CDS             6059..6352
                     /locus_tag="IXR05_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4260082.1"
                     /translation="MPDTQKSKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(6444..7304)
                     /locus_tag="IXR05_001578"
     CDS             complement(6444..7304)
                     /locus_tag="IXR05_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAQ4260083.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            7396..7824
                     /locus_tag="IXR05_001579"
     CDS             7396..7824
                     /locus_tag="IXR05_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4260084.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            7986..8162
                     /locus_tag="IXR05_001580"
     CDS             7986..8162
                     /locus_tag="IXR05_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAQ4260085.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            8189..8635
                     /locus_tag="IXR05_001581"
     CDS             8189..8635
                     /locus_tag="IXR05_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAQ4260086.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(8789..10168)
                     /gene="brnQ"
                     /locus_tag="IXR05_001582"
     CDS             complement(8789..10168)
                     /gene="brnQ"
                     /locus_tag="IXR05_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4260087.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMPLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            10874..11845
                     /locus_tag="IXR05_001583"
     CDS             10874..11845
                     /locus_tag="IXR05_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAQ4260088.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            11869..14061
                     /locus_tag="IXR05_001584"
     CDS             11869..14061
                     /locus_tag="IXR05_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAQ4260089.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            14078..14554
                     /gene="ybeY"
                     /locus_tag="IXR05_001585"
     CDS             14078..14554
                     /gene="ybeY"
                     /locus_tag="IXR05_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAQ4260090.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            14532..14933
                     /locus_tag="IXR05_001586"
     CDS             14532..14933
                     /locus_tag="IXR05_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAQ4260091.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            14948..15847
                     /locus_tag="IXR05_001587"
     CDS             14948..15847
                     /locus_tag="IXR05_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAQ4260092.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            15990..16802
                     /gene="recO"
                     /locus_tag="IXR05_001588"
     CDS             15990..16802
                     /gene="recO"
                     /locus_tag="IXR05_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAQ4260093.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            17186..18103
                     /gene="glyQ"
                     /locus_tag="IXR05_001589"
     CDS             17186..18103
                     /gene="glyQ"
                     /locus_tag="IXR05_001589"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4260094.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            18105..20180
                     /locus_tag="IXR05_001590"
     CDS             18105..20180
                     /locus_tag="IXR05_001590"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAQ4260095.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT         6782 a         3580 c         4385 g         5471 t
ORIGIN      
        1 ttttttgaca agatatttac aaaaatccac tagaaaacag taaattttgt aaatgttact
       61 ggaaagaaac agatttctat tgtttgtttt gtttacaaaa aagataatga aagtgtaaaa
      121 aagtaaagga gtgagaacat ggcaaaagga atcaaaatcg ctacgattgg tggaggcagc
      181 agttacaccc ccgagttgat ggaaggattt atcaaaagat atgaggaatt accgatacga
      241 gaaatctggc tcgtagatgt agaagaagga aaagaaaagc ttgagatcgt tagtcagatg
      301 tctcagcgta tgtgggatgc ttctccgtat gaagtcaaga tctatgcaac tctggatcgg
      361 gaagaagcat tgaaagatgc ggattttgtt acgactcagt ttcgtgtcgg tcaattagat
      421 gcacgaatca aagacgagcg gatccctagt tattatggga tgattgggca agaaacaaat
      481 ggtgctggcg ggatattcaa agcttttcgt accgttccag tcgttttggc aatcgttgag
      541 gacatgaagc gtttatgtcc aaatgcttgg ctgatcaatt tcgcgaaccc aagtgggatg
      601 gtgacagaag cagttatcag atatggcaaa tgggataaag tgattggatt atgcaatgtg
      661 ccagtgatgg cgatgatgac agaaccagca atgcttggca agaaaaaaga agagctgatc
      721 tacaagtttg ccggtctaaa tcatttccat tggcacaaag tagcagataa taaaggaaat
      781 gaccgcacgg cagaattgat tgatcgttta tacgatgaag agaatggatt accgaaaaat
      841 atctttgata tcccgttttt caaagaacaa ttaaaacaaa tgaacatgat cccttgtggc
      901 taccaccgct attactatcg tgaagaagaa atgctggaac atgctttaga agaatatcaa
      961 acgattggta caagagcgca gcaagtgaaa gaaacagaag cagagctatt tgaattatac
     1021 aaagatccag aattagacca taaacctgaa caattgcaaa aacgaggtgg cgcttattat
     1081 tcagacgctg cctgtgaaac gattgcttca atctatggaa ataaagaaac acagatcgtg
     1141 gtatctacaa agaatgatgg agctgttcct gacctgccgg cagattgtgt agtagaagtc
     1201 actgcctatg ttggcgcaca aggagcgaga aatgtagcgt ttggttctct tcctgctgct
     1261 gaaagaggct ggttgcaagt aatgaagaat atggaattgc tgacgatcga agcagctgtg
     1321 actggtgatt atgggacagc tttacaggcg tttacgatca atccacttat acgatcagga
     1381 aagacagcaa aacggatcat ggatgagttg tttattgcac accagcagta tttaccgcaa
     1441 ttcaaggaga caatcagccg attaaaagaa gaaggaatcg aagttcaaga tgaactggca
     1501 agagaattat caggtaatac acatataatg gaggaagtat aatgggattc agaaaagatt
     1561 ttttatgggg cggtgctaca gcagccaatc aatgtgaggg cggttatgat gaaggtggac
     1621 gcggactagc aaacgtagat gttgtgccaa tcggaaaaga ccgttttcct gttatcaccg
     1681 gaaagaaaaa aatgtttgaa tttgatgagg atcattttta tccagcaaaa attgcaatcg
     1741 atatgtatca tcgttataaa gaagatattg ctttgtttgc agaaatgggg ttcaagactt
     1801 atcgaatgtc catcgcctgg agtcgtattt ttccaatggg ggatgagaaa gagccgaatg
     1861 aagctggctt gaaattttat gaggatgcct ttaaagaatg ccaaaagcac ggaattgagc
     1921 cacttgtgac gattacgcat tttgattgtc caatgcattt gatcaaagaa tatggtgcgt
     1981 ggcgttccag agaactcgtt ggtttttatg aaaatctgtg tcgagtcatc ttcaatcgct
     2041 ataaaggact tgtcaaatat tggctgacat tcaatgagat caatatgatc cttcatgcac
     2101 cattcatggg cgcagggctg tattttgaaa aaggagaaaa tgaagaacaa atcaaatatc
     2161 aagcggcaca tcatgagttg gttgcaagtg ccatcgcaac gaagattgct catgaagtag
     2221 atccggagaa caaagtaggc tgtatgctgg cagcaggagc atattatcca tacacttgca
     2281 atcctgaaga tgtttgggct tctagaaaat cagatcgaga aaattatttc ttcattgatg
     2341 tccagtcacg aggagaatat cccgcttatg cattgaaaga aatggagcga aatggcattc
     2401 agatcgaaat ggaaccaggg gatgccgcat tgctgaaaga acatactgtt gattttatct
     2461 ctttttctta ttatgcttcc cgagtttcga ctaccgacaa cgaactcttg gaacagactg
     2521 caggaaatat ctttgcttct gtcaaaaatc catatctgca agcaagtgaa tgggggtggc
     2581 aaattgatcc attaggcttg agaataacga tgaatgatat ttatgatcgt tatcaaaaac
     2641 cattgtttat tgtagaaaac ggcttaggtg cagtcgatac gccagatgaa aatggttatg
     2701 tggaagatga ttaccgaatc gattacctgg cagcgcatat ccaggcgatg aaggatgcag
     2761 tagaactaga cggagtcgat ctattaggct atacgacttg gggatgtatt gatttagtat
     2821 cagctggtac cggtgagatg aagaaaaggt acggattcat ttatgtcgat cgtgataacc
     2881 aaggaaatgg cacattagcc cgttcaaaga aaaaatcatt caactggtat aaaaaagtaa
     2941 ttgattcaaa tggagaaaat ctttcgaacg attgatcaat gatttataaa agtctattgt
     3001 ttttcagcgg atttttcgag tataataaag ctattcgaga aacgcaagca gaacaataga
     3061 ctttttttcg cattggctgt aaagtatgct tacttgatta agtaaaggag aatctacata
     3121 tgtatgatgt aatcgttatt ggcgcaggtc ctgctgggat gactgctgct ttatatgctt
     3181 cacgttcaaa cttatccgta ttgatgatcg aacaaggtgc ccctggcggc caaatgaaca
     3241 atacggcaga aatcgaaaat tatcctggat tcgattcgat catgggcccc gatctagctt
     3301 ataagatgta tgaaagtgtc tcaagatttg ggacagaaaa tgcttatgga atcgttcaag
     3361 atatcaagga tcacggcagc cataaagaag tcatctgtga agataaaagt tacgaaggaa
     3421 aaacagtcat tatcgcaaca ggatgtatcc accgtaaatt aggcgtacct ggcgaggaag
     3481 aatttgctgg acgaggcgtt tcttactgtg cagtctgtga tggtgcgttt ttccgtaaca
     3541 aacgtctagt agtcatcggg ggtggggact cagcagtaga agaagccatc tatttgacac
     3601 aatttgcttc tgaagtagtg atcgtccacc gtagagatga attacgtgca caaaagatca
     3661 tccaagaccg tgcatttgca aatgaaaaaa tttcctttat gtgggataca gtcgttgacg
     3721 aaatcgttgg aaacgaaatg gtagtgacag gtgtgaaagc acgtaatgtc aaaaccggca
     3781 atgaatttga tttagcagca gacggagtat tcatctatgt tggactggat ccattaactg
     3841 caccttttag agaagcaggt ttgacgaacg aagctggctg gattccaaca gacaacgaaa
     3901 tgaaaacgaa tatgccaggc gtttttgcca tcggagatgt tcgtgaaaaa gatttgcgac
     3961 aaatcactac agctgttggt gacggcggta ttgctggaca acaagtgtat aaatacttgg
     4021 agtctttaga agaaacaaca gcataagttt aaaaagagta gaagaacggg ttcaattgtt
     4081 cttttactct tttttttcgc gtgaaattta ctgaatctga tttatgcgaa cacgtccaac
     4141 accttttgat aaaagaatcc tttcttgatt taagcgtttt ttggtcctca tactttcata
     4201 tctaataagt gaatgctata cttattaaga accatatttc agaaagaggt gttattttca
     4261 tgtcttggga acaagtgtat gaacaatggg tacatgaaga aaatttagaa gaaaacttaa
     4321 aaaaacaatt aaatgatctg ggtgaagatc ctgaaaaact tgaagatgct ttttatgcac
     4381 cgttggaatt cggtactgca ggtatgcggg gaatcttagg acctgggatc aatcgaatga
     4441 acatctatac ggtaagacaa gcaacagaag gactagcacg tttcatggat acacaaggtg
     4501 aagaaacaaa acgccgaggt gtcgctatcg cttatgactc acgccatcag tcaccagaat
     4561 ttgcaatgga agcagccaaa acactagcac atcacaatat cccgtcttat gtattcgaaa
     4621 gtctgcgtcc aacaccagag ctttcttttg cagttcgtca tttgaagacg tttgcgggaa
     4681 tcatggtaac cgcatctcac aacccagcgg cttacaatgg atataaagtc tacggagaag
     4741 atggcggaca aatgcctcct gcagacgcag atgcattgac gaaatatgtc cgtgaagtca
     4801 gcaatccgct aaaagtcgaa gtattatctg acgaagaagc taaacatagc gggttgatca
     4861 cgatcatcgg agaagaagtg gacgctgctt atctagaaga aatcaaagca gtgacgattg
     4921 atcgtgaatt ggttgaaaca atggggaaag atttgaaact tgtgtacacg ccacttcatg
     4981 gaacagggaa aatgttgggc gaacgtgcgt tgaaacaagc tggattcgaa caattcgtac
     5041 tagttcccga acaagctgtg gcagatccag atttcactac ggtcaaatcg ccaaatccag
     5101 aagaacattc agcttttgaa tatgctatac gacttggaga aaaagaagga gctgacttgc
     5161 tgattgcaac agatcctgat gcagaccgtt taggcgcagc ggttcgtttg ccagatggtt
     5221 cttatgaagt attgactggg aaccaaatcg gagcattgtt tgctcaatat attttggaag
     5281 cacatcaatc aagaggcact ttaccagaaa acgcagcggt attgaaatca atcgtttcca
     5341 gcgaattgcc tacagcaatt gcggaacact acggtgctac catgttcaat gtgttgacag
     5401 ggtttaaatt cattgctgaa aaaatccaac aatttgaaga agaccattca catactttta
     5461 tgtttggatt cgaagaaagt tatggttatt tagttaaacc ttttgttcgc gataaagacg
     5521 cgatccaagc attgctttta ttagcagaag tagcagctta ctataaaaaa caaggcaaaa
     5581 cgttgtatga cggcttgcaa acgatttttg aaacctatgg ctatttcgca gaaaaaacga
     5641 tttctgtgac aatgagcgga caagaaggtt ctgcgaaaat ctctgctttg atggaaaaat
     5701 tccgtaaaga agcaccgaca gaatttgccg gagcaaaagt tattcaaaca gaagacttta
     5761 aagaattgac gagaacagac cgtgaaggaa acgtagaaaa actaacaaca ccgccatccg
     5821 acgtattgaa gtatacattg gaagaaaatg gctggatcgc tatccgccct tcaggaactg
     5881 agccgaaaat caagttttat attggtgtaa aaggaagctc tacagaagac gcagccgaaa
     5941 aagtagcctc ttatgaagcg attatcaaaa agatgacaga agaataaaaa acttgagact
     6001 gatggaaaaa gtggtaaact ttagaagtca gtcttttttc aagttggagg tgaatggatt
     6061 gccagacacg caaaaatcaa aagtagagaa agtcagtcaa ttattcaaaa tgttgagtga
     6121 tcccactcgt cttaaaattc tgctatatct gaaagacggg gaacaaaatg tgacagcaat
     6181 cacccaagca gtggaaatgg agcagtctgc tgtatcgcat caactacgtt tattaagaga
     6241 aaatcatgtc gtcaagtctc atcgcgaggg aaaagcgatt ttgtatagtc ttgatgattc
     6301 tcatgtactg gatattttga accagacact caaacatgtg gaacatcaat aacgataggt
     6361 gaaaatagat aaacactgga gtgtgacaac gaagaaattt cgttgtcaca ctccagtgtt
     6421 ttttaagaaa aagacaaaaa tgattaatcg cttttttctg ttgtttcagt tccataataa
     6481 ctatgatctt ctaggtctaa agcattcaaa ataagcgaag ccgtttcttc aatagataaa
     6541 gatgccacat tgatcactac acatcctagt ttttcataaa gatcattcgc aaaatcgagt
     6601 tcagctctaa ttttttcgat atcggaataa gcagtatcag ggtttaatcc gtaagagcgc
     6661 atccgttctt tacggatatt atttaaaata tctgggttat tcgttagtcc cacgattttt
     6721 ttaggatcga tttcccacag ctgtttggga atatgtgctt ggggaatcaa aggtaaatta
     6781 gcaactttta aatttttatt tgctaaaaac aagctcaaag gcgttttgga agttcgggat
     6841 acgcctagca aaacgacatc tgcttctaaa aaaccacgag gatctttccc atcatcgtat
     6901 tttacagcaa attccattgc tttgatccgt ttgaaatagt tctcattcaa taaatggagg
     6961 gcaccaggtt gccgaattgg cttgatacca gttaaacgtt caatttctga tatcggtggc
     7021 gtcatcacat cgaaactaaa taattgatgt tcttcacaaa aagaacgtgt tatctcgatc
     7081 agttcttgat tgattaatgt atgcaggaca agtgcttttt cttctaatgc atcttgcaat
     7141 gcctgcctta atgttttttc atctgtcacg aacgttctgc ggaataggtt gaactcaacg
     7201 gtaggatact gagccatagt agcttgcgct agttttgtcg cagtttctcc agcagagtcg
     7261 gagatgacaa aaaaagtaac gatttctgta gaatcggaag acatggataa aacctcactt
     7321 gcattttttt tatgtttatt ataccatact ctagaatgcg tacttcgtaa tcattttgat
     7381 ttggaggaat aagtcatgaa aaaacagaca ttgatcgaac aatcattaga aacattgaaa
     7441 aataacggtt ttaaatatac taaaaaaaga gaagcattgt taacttattt agtgaagcgt
     7501 aaccgctacg tatctgctaa agaagttttt gactatatga atcaggaatt caaaggggta
     7561 agttatgata cgatttaccg gaatctccat gattttgcag agatcgattt actggaagaa
     7621 accgatttaa atggtgaaat gaagtttcgt tttcattgct gtcaggggga aatcggccat
     7681 caccatcatt ttatctgtac agtgtgcgga acaacgaaag aaatccatat gtgtccaatg
     7741 aattatttcg aagaacagct aggtggatgc acgatcgaag ggcatagatt cgagattttc
     7801 ggaagatgtg aaaattgtca ataaggattt aaataaaata acatttgata atttaaaaaa
     7861 aaagcaagat ttccttgacg gtcaaaacag cattagatat aatatttaca ggacagtctt
     7921 gttttttgag atatatttca ataacaatta cggttacttt ttaagctcgg agggagggaa
     7981 ttaacatgtc aaaaacagtc gttcgcaaaa acgaatcact tgacgatgct cttcgtcgct
     8041 tcaaacgttc cgtgtcaaaa gcgggtactt tacaagaatc tcgtaaacgt gaattctacg
     8101 aaaaaccaag tgtaagacgc aagaaaaaat ctgaagcagc tagaaaacgc aaaaaattct
     8161 agttctgtga tgaattggag ttggtagtgt gtcactacta agtagattaa acgatgacat
     8221 gaaagcagcg atgaaagcga aagataagga atctttacaa gtcatccgaa tgatcaagtc
     8281 atctatacaa aacgagcaga ttaaagaagg tcacgacttg acagaagaag aagaactaac
     8341 ggtgttgtct cgcgaaatga aacagcgacg tgattctttg catgagtttg aagaagcagg
     8401 acgtgacgat ttagctgaaa aagtaaaaag tgaaattgta atagtcgaaa aatatatgcc
     8461 ggaacaactt tccgacgaag aaattcgaca acttgttcaa gaagcaatca ctcaaactgg
     8521 tgcttcatca atgaaagaat ttggcaaagt tatgggtgca attatgccta aagtcaaagg
     8581 aaaagcagat ggaaaccaag tgaatgcgat tgtgaaagaa ctattacaat cttaatttta
     8641 tcatttaaac tgcggacagt gattgtccgc agttttttgt gttcgtaaaa aaagaactaa
     8701 aaaacagcta gaagaaagaa taagattctt tcttctagct gtttttttcc tgtttaatat
     8761 ctcttatgtt aaattgtgtt tgatttggtt attcttctgg tagttcattt gcttcttgtt
     8821 tataccctga taggcgatag gcgtaataaa agagtaagct gccagcgtaa ccaagtaacg
     8881 ttgggaccat ccagccaagt cctaatgcag caaaaggaac gtgatgatga taaaatccta
     8941 gtaagcttgc tacgacagtt tgctgactca ctaatgcagg cgaatttgcc aacatatcca
     9001 atacggctgg aacggcagaa aagaacatcg ttacttgata gacaaatgga ctcttttgga
     9061 agaattttgc tgttaaggaa agcaagatta acgcaagtga caatggatac aaaagcatca
     9121 atactggtaa agaccattgg atgatattat ccaatccggc attcgcaacg acaaaagaga
     9181 caaaagtcgt taaccgcagc catgtcatat aactgacttt agggaacagt ttatggaaat
     9241 cttgtgcaaa agaaacaacg agtcccatag cggtagtgaa gacacctaat gtgaccatta
     9301 cccctaagaa gctagcaccg aagttaccta aataaaaatt agtgatctga gaaagtgcag
     9361 ttccgccatt ttctgataaa ggcatcttat tcaaactcat cgcaccgaga aggaccagac
     9421 caaaataaat catgacttct aacgcaacgc tcaggctacc agcttttgct gttaattctg
     9481 tgactttttt atctttaaaa ccaagatcac gaactgcatg gacaaaagtg acacttaaag
     9541 caagtaaagc tactgcatca accgtgttgt atccttctaa aacgccattt gtcaaagcgt
     9601 tcgtctgata agaatctgca gcagattggt ttagattccc catgggttgg aataaagaaa
     9661 cgacaaaaat gatagctaat aatgcaagaa acaaggagtt taaatacttt ccgacatatt
     9721 tgaccaaacg tgttggatgt acagtaagga aataagcaag taaaaagaaa agagcagaga
     9781 ataaaaacat acctaatgaa tcatattttt caggcaaaaa gggtttagca gccatttcaa
     9841 aagcagttgc tgctgtccgc ggtgtaccaa agaatggtcc gatcgttaaa tgaacaagga
     9901 tcaagaacaa ggcagcatac cattttccga caggtttagc taagtcatac agaccatcac
     9961 tttttgtcac tactacagct aagatagcta ataatgggaa aagagcgcct gagatggcaa
    10021 atcctacacc agcgctgatc cagtttgatc cagccatttg acctaagtgg acaggaaaga
    10081 tcagattacc tgacccgaag aacatcccga agataagtga actgaccatc aataattgct
    10141 tccatgaata agtttttgtt tcttccataa atttttcctc caataattat cattttgagt
    10201 aacaaaataa acgttgcaga aactagaaat gccactaata tcagattcca tgaaaaccac
    10261 caccttaaaa tataaaaaaa agcccttttc cacttgggaa aagggctcta gattctagaa
    10321 cggtaccacc ttttttcgct taaaaaagct tcttcattca cggacgcttt tcgataaagt
    10381 tatccgctag cctgataatg gaggcagcca caatgatcta cgttttcgac attgactcgg
    10441 aaatgatgtt cgtctattcg atttattgtc atttctcact tacatgactc actgggaata
    10501 aatcgctgaa tagcctactg ttttcctcga cgctttgctg tatatttatt tgttgacgtt
    10561 ataatacacc tgtttttttt gaaatgcaag aatatttcaa atattttgtt ttcttttttt
    10621 gaaacaagaa aaatacccag agaatacttg ctaagttaga cggaatactt gtcctctatc
    10681 ttatgcatag cttacatgat cagctttttt tattcaaacg agacctttag agaatggaag
    10741 cagctatttt ttaacgtttc ttggtactta tggttaagca actcttttag aaccttttct
    10801 tatttgctat atagtttctt ctgagtatgg taaaatagga aagaatgaat cgaaaaaaag
    10861 gggatgtcta tttttgacgg aagagtctag ttctttagag attagattga cggctgctga
    10921 tgatgtcagc atgcttttag gtgcacacga caagcatata aaactgattg aagaaacaac
    10981 agaaacaacc atccatacac gtggagaaat cattcagatc attggcgaac aatcccagat
    11041 ttccttggct gcctcagtca ttcggacatt gcaggaattg atcaaacgag gaatccatgt
    11101 aagtacacca gatgtcgtga cggcactgaa aatggggcaa aaaggcacat tagattattt
    11161 tgttgaaatg tatgaggaag agatcgtcaa agaccgtaat ggaaaaccaa tacgggtaaa
    11221 aaacagcggc caaaagaaat atgtcgaatc ggtagccaaa catgatatcg tatttggcgt
    11281 aggaccagcc gggacaggaa aaacttttct tgcagtagta ttagcaatcg ctgccttgaa
    11341 aaaaggtgaa gtgcaaaaaa tcattttgac gcggcctgct gtggaagcag gggaaaatct
    11401 aggctttctt cccggggatc taaaagaaaa agtagatcct tatctgcgtc ctgtttatga
    11461 tgctttatac caaatttttg gattagatca tacgaaccga ttgatggaac gaggcgtgat
    11521 cgaaattgct cctttagctt acatgcgggg gcggacattg gatgatgcat tcgttatttt
    11581 ggatgaagca cagaacacga cagttgctca gatgaaaatg ttcctgacac gtcttggtta
    11641 tcaatcaaaa atgattgtca atggagatac gagtcagatt gatctgcctc gagggacaac
    11701 aagtggtctt gttcatgcag aacgaacatt aaagcaaatc aagaaaatcg attttgttaa
    11761 ttttgaagca agtgacgttg ttcggcaccc tgtagttgcc gaaatcatca aagcttatga
    11821 aaaggcagat ctccatcaag aataagcttt gcttaggagg ataagcacat gttgaataaa
    11881 acactgcaga aactacaaga aaaacttgga aaggcagcat tgcctttcct gctgttcttg
    11941 ttttttatca ttatctgcgg cgttacattt agtagtgtca aacaaaaggc caatgatttc
    12001 agagaaggcc aagtagcaga agaaagtatc cgtgcgaaca aaacgatcga gaacacggaa
    12061 gaaaccgaac aaaaaagaaa actggcagca gaagcagtca ctccagaata cacttaccaa
    12121 aaagatcttg cagatgacca gaacaatcgg atcaagcaac tatttgaatt gatcgataaa
    12181 acgaatgatg ccatcaacaa atcttatgac gaaaagattg ataaggcaaa ggaagatgaa
    12241 aatatcccaa agcctactac agaagagcgg atcgccgcgt tgaagaaaaa ttttgaaaat
    12301 gtgaatgcag aaaatgttgc gttttatcaa aaactaccga acaattttta ttcgacgata
    12361 tttgaaatga ctgaaactga gatccatact gtgagggatg agagtctgaa gctcattgac
    12421 gaacagatga gcaaacaagt tcgtgaaagt gaattggaag cttttaaaca agaagcagaa
    12481 gagcaaatcc aatatttgaa tgtcacacca gcacaacaac aaatgattcg ctacttagtg
    12541 gatcaaggta tcgtagtgaa tgacgtattg aatgagaaaa agacagaaga attgaaacaa
    12601 tccgcacgag aagctgtaca accagtgatg atcttccaag gagaaatcat tgttcgtgaa
    12661 ggtaatcaaa tcgatgcttc agctatgaaa aaattggaat tactaggact gactaatcaa
    12721 acaacttcga tttttccgct aattgccatg gttttagctg ttttgcttca aatcggcgta
    12781 ctgatttata attcacttca attccaaaat gcaggagaaa gaacaaaata cgtgcttttc
    12841 tatgtgacag ctatgtcagt cagcatagtg ctgatgaaat ttttccaatt attccaaacg
    12901 gaacaagcta cttatatccc gctgttttat cccgctgctt ttgcaccact tgttttaagc
    12961 tttttcttga accgaagagc agggatcatg gctggtattt tccaagcagt atctgcactt
    13021 ttcatttttt atgattcgat tggcacgaac tttctaacga ttatcttgat gtcttatgtt
    13081 ttctctgggc tcatggcaac gattgtcaga cgcaaacgga tctcagaaca aggattatct
    13141 gctgccatgt gggtcattat ttttcctgtg atgatggatg tcattttgat cgtctatcaa
    13201 ggaatgagct ttggtgatgc aacgacttgg ttaatgcttg tctgcgggtt cactggtgca
    13261 ctcttctcat tcttgctgac gatcggtcta cacccatata ttgaattgat ggtcaatgat
    13321 gacagtgtaa ttgtattaaa tgaactcagc aatccaaatc atcctttatt gaaacagttg
    13381 ctggaagaag cgccaggtac ttatcatcat agtatgatgg tagctaatct aagtgctaac
    13441 gctgtagcag aaatcggcgg acgttctttg ctaactcgag tagcttgcta ttatcatgat
    13501 atcggcaaga tcaaacatgc tagctttttc gttgagaact tgccttcagg agcggaaaac
    13561 ccgcacaatt tcttattgcc agaagacagt aaacatatta tctttggaca tgtgacagat
    13621 ggagccaaaa tattggaaga ttataatatg ccgcaaatgg tgatcgatat ttgcaaacag
    13681 catcatggaa ccacgctaat gcgttatttc tacatcaaag cgaaagaacg caatccggaa
    13741 gtaacagaag agcaattccg ttatcctgga ccaaaaccgc aaagtcgtga agcagggatc
    13801 gtcaatattg ctgacagttg tgaggctgca gtacgggcaa tggatcatcc gacgagcgaa
    13861 aaaatcgaaa gttttgtcca taatcttatc gaagagcgta tttccgatgg tcaattagac
    13921 gatagtggac tgaccttgaa agaaatccga aaagtggaaa aatcattgat cagcggttta
    13981 agtagcacct tccattctcg gatcaaatat cctaaaatga aaacagaagt tgagaagata
    14041 aaggaagaac aagaagaata gaaagaagcg atgtataatg gatattacct ttatggatga
    14101 aacaaaccaa gtctcagaag agaaaatgaa agaaatcgat gacttgctgc aatttgcagc
    14161 atcttattta aagctgccag aggaaacaga aatgtctgtt actttcatgg acaatgcggc
    14221 aatccaagta atcaatcgtg attaccgtgg aaaagatgca ccgacagacg tcatcagttt
    14281 tgctctggaa gaagaaggcg aagacgaaat cccagtgatt tttgaagatg gagagaatcc
    14341 attgcctcgt gtactaggag acatcatgat ttctattgaa cgtgctgctg aacaagcaga
    14401 agcttacggc cattcatatg atcgggaact tggcttttta gcggtacatg gattcttgca
    14461 tatcaacggg tatgaccata tgacaccaga agatgagaaa gaaatgtttg gtttacagaa
    14521 agagatcttg gatgcctatg gactcaaaag ataaaaacgt agagaaaaac aaacatttcc
    14581 tgatgtctgt ggaatttgct gtccaaggag tcaaaaccgt ttttgaggaa gaacgcaata
    14641 tgaggaaaca tgttgcgttc ggtatccttg ctttatttat gggcgtgatt ttccagcttg
    14701 atcggataga gtggttatgg ctgcttttag ctgtttttct cgtttggata gtagagatca
    14761 tcaatactgt ttttgaaaat gtagtggaca tgtttacgga ttttcatttt catccgattg
    14821 ggaaaaaaat caaagatatg gcagctggag cagttttagt gaccgcttgt tttgctgtca
    14881 tcattgggtt gattttattt gtccctaaaa tatatcattt gttgtttaat taaaaaggag
    14941 aacgtatatg ccagaacata aatcagggtt tgtcgcaatc gtcggccgcc cgaatgtagg
    15001 aaaatccaca ttattgaacc gaatcgtggg tcaaaaaatt gccattatga gtgacaaggc
    15061 acagacaact agaaataaaa tccaaggagt atatactaca ccagaagctc agctgatttt
    15121 tatcgataca ccaggaatcc ataaaccaaa gcatcgtcta ggagatttta tggtagaagc
    15181 agcttacagt gcgttgaaag aagtggatgc agtcttattt atgatcagtg ctgatcaaaa
    15241 acgcggccgg ggagacgatt ttattattga acgtctaaaa aacgtgcatt ctccagttta
    15301 tctgattatc aataaaatcg ataagatcca tccagacgag ttgctgggaa tcatcgaaga
    15361 ttattcgacg cagatgcctt ttgcacaagt gattccgatc tctgctacag aaggaaacaa
    15421 tgtcgaacgc ttaatggatg tattagtcag tgaaatgcca gagggcccac aatattttcc
    15481 agatgatcaa gtgactgatc atcctgaata ctttatcgtt tctgaattga tccgtgagaa
    15541 agtcttgttt ttaacacgag acgaagtgcc tcattctgtc gcagtcgttg ttgattcgat
    15601 gaagcgaaac gagaatgata aaatccatat ccaggccacg atcatcgtcg aaagagatag
    15661 ccaaaaagga atcattatcg gcaaaggcgg aaaaatgctg aagcaagtag gaacgaaagc
    15721 aagaaaggat atcgaaaatc ttttaggaga caaagtattt ctagaacttt gggtcaaagt
    15781 ccaaaaagac tggcgagaca aaaaagtcta tctgcaagac tttggctacc gaaaagacga
    15841 atactgatat tctgaacttc ttataggtta agtatagaaa taaactggat aaaaatccgc
    15901 acgttgagaa aaacggcgga agatcgaaac ataaataatc tggatcggca gaatctgctt
    15961 ttccagattt attttttagg agggagaata tgagccagct tgcagaatcg aaaggcttga
    16021 ttttatctag ccgtaattac aaagaaaaag ataaattagt caaaatcttt acggaatctt
    16081 ctggcaaaat gatgttttat atcaaaggaa tccatcggca aaatcagcca ttagctccgg
    16141 ctttgctccc ctttaccgaa gcagtctata tcggtaattt tcgaagtgaa ggtttgtcgt
    16201 ttttaagcag tgtcaaagac gtccatgcgt ttcggaacat ccaagaagat atctttttga
    16261 gcggttatgg tacctatttg ctaaatctag tagatgcagc aatcgaagat catcaatatg
    16321 acccgcattt attccaattt acgcaacaag ctctgcagcg gatggatcaa ggagatgatg
    16381 cagaaatcat cacgaatatc tttgaagttc aaatactgca acgcttcgga atcgcgccaa
    16441 tttggacgca ctgtgtcgta tgcggggaaa caaaaggaaa atttgactat tcttccaaat
    16501 ctggcggtgt gatatgcgag aaacactggc caatggacga acaccgttat catgcagatc
    16561 ctcgcgctgt ttatttcgtt cgaatgtttt cggctatttc ttatgataag atcagtggaa
    16621 tccacttgaa agaagaaacg aagcaggcaa tccgtgacct cattgaccag ttgtatgatg
    16681 aatatgtcgg tattcatcta aaaagcaaaa agttcattga tcaaatgaag tcttgggcac
    16741 acgtattaaa gacgccagag aaaaatatgc ctgaaaaaga gatacctgaa aaagaagaat
    16801 aaatgaaaga tacaacaaaa aaatcaaaac tatttgacaa atacagggac ttccgtctat
    16861 tattaaccgt agattaaata gatcgttcac tgagaggatc tattatataa acaagaaaac
    16921 tgcaaaatga atacgtacat tgaccaagat cagtaaaaaa cacgtggttt agcgagttcg
    16981 ggagagtgga agccggaccc aaacgatttt tgaagaggca cttgcgagta cgataaatga
    17041 agctgccgaa tctttattcg gaagtagggt ggaaccgcga aattattcgt ccctatgtct
    17101 gtaatcagac atagggactt tttgtcgttt tctttcctgt attcttattg acagcaacgc
    17161 ttaaaaattg aaaggggcaa aacagatgag taaaaaattg accgtccaag atatgatttt
    17221 aacattacaa aaattttggt catcaaacgg ctgcatgctg atgcaagctt atgacacaga
    17281 aaaaggagca ggtacgatga gcccatatac attcttacgg gcaatcggac cggaaccatg
    17341 gaatgctgct tatgtagagc catcccgccg accagctgac gggcgttatg gagaaaaccc
    17401 aaaccgtttg tatcagcatc atcaatttca agtcgtaatg aaaccttcac ctgaaaatat
    17461 ccaagagctt tatttagaaa gcttgcgtct tttaggaatt gatccattag aacacgatat
    17521 tcgttttgtt gaagacaact gggagaaccc atcgatgggg tgtgccggtg tgggttggga
    17581 agtatggctt gatgggatgg agatcacaca attcacgtac ttccagcaag tcggaggact
    17641 accttgtaaa ccagttactt ctgagatcac ttatggacta gaacgtcttg cttcatatat
    17701 tcaagaagtt gaaagtgtct atgatctgga atgggctgat ggtgtgaaat atggcgagat
    17761 cttcaaacaa ccagaatatg aacattccaa atattctttt gaagtaagtg accaagactt
    17821 gctactaagc aactttgacc gttttgaaaa agaagctaaa cgctgtatcg atgaaaatct
    17881 tgttcatcca gcgtatgatt atattttgaa atgcagccat acattcaatt tattagatgc
    17941 tcgcggtgca gtatccgtaa cagaacgagc aggttatctt tcccgtatcc gcaacatggc
    18001 tcgtgctgta gccaaaatct ttgtggcaga acgcgaaaaa ttaggattcc ctttattgaa
    18061 taaaaacaca gcaaatccag aaaacatgaa ggaggctgaa taagatggca aaagacttat
    18121 tacttgaaat cgggctggaa gaaatgcctg ctcatgttgt cacaccaagc atgaaacaat
    18181 tagaagaaaa aacagcaaaa tttttagatg aaaaccaatt gacttatgat acgatcgaaa
    18241 cgttttctac accgcgccgc ttagcaatca aagtaacaaa cattccagaa cgtcaagcag
    18301 acagtgaaga agaagtcaaa ggaccagcca aaaaaattgc tttggacgca gatggaaact
    18361 ggacgaaagc agctgaagga tttgtccgcg gacaaggtct gacgacagat gctatcactt
    18421 ttagagaatt aaaaggcgtg gaatatgtct atgtaacgaa atacactcac ggcaaagaag
    18481 cgaaagaagt attgacaggt ttagcagatg tcattaaaag cctcactttc ccagtaacga
    18541 tgcattgggc agaatacgat tttgaatata tccgccctat tcactggatc gtggcattgt
    18601 tagatgacga agtaatcccg tttgagatct tagatgtcaa aacaggcaga gcctctcgag
    18661 gacatcgttt cttaggcgaa gatgtgacat ttgcgcatgc aaaagaatat gaagaaaaat
    18721 tgaatgaaca attcgttatt gcttcaccgc aaaaaagaca agaaatgatc gttacacaag
    18781 caaatgaatt agccgaaaaa aatcactggg ttattgatct agacgaagat ttactagaag
    18841 aagtcaacaa tttagtcgaa tatccaactg tcttttctgg cgacttcgaa gaaaaatatc
    18901 tttctgttcc tgaagaagta ctagtcactt ctatgaaaga acatcaacgt tatttcgagg
    18961 tacggaacga tcaaggtatg ctgcttcctc attttatttc tgctcgtaat ggtgatcggg
    19021 taaaattgga aaatgtggtt cgaggcaatc aaaaagtatt gacggctcgt ttagaagatg
    19081 cggaattctt ttataatgaa gacaagaaag cttcaatcga ccaatacgtt gaaaaactaa
    19141 aaactgttac tttccatgaa aaaatcggta gtatctatga gaaaatgcag cgggtacaag
    19201 tcattgcccg tatcattggc gaacaagtag gactatctga ggaagaattg atggatctgc
    19261 aacgagctgc tgaaatctat aaatttgatc tagtaaccaa catggtaggg gaatttcctg
    19321 aactacaagg gatcatgggc gaaaaatatg ctctgctgaa aggcgagaaa cctgctgtag
    19381 caacagcgat tcgtgagcat tacatgccta tatccagtga aggagagcta cctcagtcta
    19441 cagtaggttc tgttttagcg attgcagata aattagatag cattttttct ttctttgcag
    19501 ttgggatgat tccaagcggg tcaaacgatc cttatgcctt acgtcgccaa gcatacggtg
    19561 tcgttcggat catcgaatcg aaaaaatggg cctttccttt gtctgttctg caagaaacga
    19621 ttagtgatgt tatcagtaaa gatacggatc gtttcggcat tggtttatca gaagggcaac
    19681 aacaggtgat cgactttatc aaaggccgtc tgcgccaatt attgacaacg aagaatattc
    19741 gtcatgatgt catcgaagct gttttgaatg cagaacaaaa agatctgaca aaagtatttg
    19801 cagcagcaca attgttcaag cagcatcttg cagatgaaga cttcaaacca tcgatggaag
    19861 ctttgacacg tgtcgtgaac ttagcgaaaa aagcggagct tgaaaaacaa tcagaagtag
    19921 accctgaact gttcgaaaat gaagcggaga aagaactgca caaagcagta gaggcaatga
    19981 aaaaaagctt tgctgaccaa acgatcaacg aaaattatga tcagcttgta agccttcgcc
    20041 cactgatcga aaattatttt gatcagacga tggtcatggc agaagaacca gcagtacgta
    20101 agaaccgatt aacgcaatta agtcaaattg ctgccatggc tttgtcgcta gcaagtttag
    20161 atcaaatcat cacaaaataa tttctaatat gtaaataaac cagagaatag gcacaaaa
//
LOCUS       DACGDM010000040        19873 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.041, whole genome shotgun sequence.
ACCESSION   DACGDM010000040 DACGDM010000000
VERSION     DACGDM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.041"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            202..1077
                     /locus_tag="IXR05_001591"
     CDS             202..1077
                     /locus_tag="IXR05_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260096.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(1222..1374)
                     /locus_tag="IXR05_001592"
                     /pseudo
     CDS             complement(1222..1374)
                     /locus_tag="IXR05_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(1642..2973)
                     /locus_tag="IXR05_001593"
     CDS             complement(1642..2973)
                     /locus_tag="IXR05_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260097.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(3122..3835)
                     /locus_tag="IXR05_001594"
     CDS             complement(3122..3835)
                     /locus_tag="IXR05_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4260098.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            4010..5434
                     /locus_tag="IXR05_001595"
     CDS             4010..5434
                     /locus_tag="IXR05_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4260099.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            5733..6440
                     /locus_tag="IXR05_001596"
     CDS             5733..6440
                     /locus_tag="IXR05_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAQ4260100.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            6427..6750
                     /locus_tag="IXR05_001597"
     CDS             6427..6750
                     /locus_tag="IXR05_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4260101.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(6839..7876)
                     /locus_tag="IXR05_001598"
     CDS             complement(6839..7876)
                     /locus_tag="IXR05_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4260102.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(8197..9180)
                     /locus_tag="IXR05_001599"
     CDS             complement(8197..9180)
                     /locus_tag="IXR05_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAQ4260103.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(9595..10365)
                     /locus_tag="IXR05_001600"
     CDS             complement(9595..10365)
                     /locus_tag="IXR05_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4260104.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(10358..11293)
                     /locus_tag="IXR05_001601"
     CDS             complement(10358..11293)
                     /locus_tag="IXR05_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260105.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(11609..13258)
                     /locus_tag="IXR05_001602"
     CDS             complement(11609..13258)
                     /locus_tag="IXR05_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4260106.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(13375..15978)
                     /locus_tag="IXR05_001603"
     CDS             complement(13375..15978)
                     /locus_tag="IXR05_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4260107.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(15990..17039)
                     /locus_tag="IXR05_001604"
     CDS             complement(15990..17039)
                     /locus_tag="IXR05_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAQ4260108.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(17065..17379)
                     /locus_tag="IXR05_001605"
     CDS             complement(17065..17379)
                     /locus_tag="IXR05_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAQ4260109.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(17395..17841)
                     /locus_tag="IXR05_001606"
     CDS             complement(17395..17841)
                     /locus_tag="IXR05_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4260110.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(17842..19818)
                     /locus_tag="IXR05_001607"
     CDS             complement(17842..19818)
                     /locus_tag="IXR05_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAQ4260111.1"
                     /translation="MKIEIIIVHLSCIQEVKIMGIEFSERQMKILYFLIENEHTTYKE
                     LSEQLYVSTKTISKDILILKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKIN
                     IADSPEDRLTYVFAKLLNTNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLV
                     SDRNGVRIKADEKSKRRLMSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDI
                     LKKVAELLNRYMNKTQLKFTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNT
                     LILIKMIEKAFSIIVPIDEQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVR
                     IKLNEFYPDEELINNLVLHLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEE
                     IEERFCIHFNEDEIAYVTLHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFA
                     DMVEIEDVLSINELQDRKVTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQL
                     NEQTEDAFLNLLDKRFCFFTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKL
                     SSTAMNDFAMPHIEVDFIKKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKI
                     YETFNEIASNHELLANLKTSSSFEKLVYILKEGL"
BASE COUNT         6075 a         3966 c         3230 g         6602 t
ORIGIN      
        1 ataaataaaa aacaaaaaaa gttccatctt taaaacacgc tattctttta ctttttctca
       61 cattctctaa gaaaagaaaa ggagaatgaa tttttgacaa ttcgagcaaa agtgattatc
      121 aaatatgtaa aatcagctac ttttttctta aacgtttctt tatactaaat ataaataagt
      181 gtttcatgaa aggagaacta gatgaataat tggcttgagt attttcctga aaacgttttg
      241 gaacgcggtt acagctatca tctgcacggt tttgtccgtc atttgaacta tacaagcaag
      301 tacttgtccg caacagtttc tggcacggaa gattataagg tagtgatcac ttgggatgaa
      361 aagaccaaca tgacttgtga ttgtctatat gccatagaag gaaaaaaatg caaacacatg
      421 gctgctgtct tattcgctta cgaagaacgt ccaataaaaa aatccaacta ctcactttcc
      481 gaactctcgt cccttgtttc ctccgctagt tcctctcttg tacgggagct tttaacagag
      541 attcttatag aacatccgca atttatcgaa cgcttcaaag ttaagatgcc atttcatgca
      601 ataaattatt cagataaatt aacaactatc atccataaat acgatcatat tatcaagaaa
      661 aacaaaaaca ggaaaacagc gaagttcatc atggagatgc gaaagttcat ccaagaagca
      721 gttgaatcgc tcattcagca aaatgcctat cttcccgcat tcgaattgat caatgaagtg
      781 attgctactc tcgaaacatt ctattgggag cctgaggatg aacgaaccct tcttctgata
      841 gaggactgtt attatttatg gaaagaatta ttagcagaag cacctcatgc agaaaaaagg
      901 caaatgttct cttggttcgt ctgccaagtc gatcatactg acgcctctta ttcaaaacgc
      961 tactccataa aaatcctgaa agaagacttt cgggaaaaag aattttctaa ccaaaagaaa
     1021 aaaatagata aaaaaactaa agaaacggta aagaaagacg atttcaatga aaaatagcaa
     1081 gtaaacgata acaaccatcc taaatccaca agaaatacag cagaccttgc tttaaaaaca
     1141 cgaatcatgc aaaggatgaa gtaaagaaga cttaacgcgt acccaatatt agtcatttga
     1201 ctattaggta cgcgttttgt tttataagtc atgacaaatt tccttcgttg ctgggtagat
     1261 tttccggcat tgttgataga ttttatgata cttttctaca ttttgtaaga gaggttccac
     1321 tgcatctgta tattggataa aattctgaca acaactttca ggtgtgtcga accactctaa
     1381 tctttaaaga taaatattaa aataacgatt aataatatta acagtcttta tttttcacca
     1441 ccaaaaacct atctttgcat atactaaata gacgtatata cacagatagg tttgtcttgt
     1501 gaaaaataat gattatcctt accaaaaaat gtttgttttt ctacatgttc gtacttatca
     1561 aaaaatatga tccttattga aattactggc tatttatatt ccaacgactt cttgtgttaa
     1621 tttttgttat ctcatagtaa attatgtttc attttcactt aatttagttg tcacgtgttc
     1681 gtcaattcgt aaaaacggta aatatataaa cacacttgcg gctataatta atatttgtaa
     1741 aacagctgct cgccagtctc cggctgttgc taaaaatccc gatataactg gtggcgtagt
     1801 ccaaggaatt tgcactacta catgattaat taatcccaca gcagttgcaa aatatgctac
     1861 tgtcaaagaa aaaatcggtg caagcacaaa gggaataatc agactgatat taaatacaat
     1921 aggcaatcca aaaataatag gttcgcttat attgaatata gcgggagtta ccgataattt
     1981 agcaaagtcc ttataatctt ttctacgact gaagataaat attgcaatca ataaagcaat
     2041 cgtatttccc gatccaccca ttaccgcaaa ggtatcttta aaggccatat tgataatatg
     2101 tggaatttgc tctttgtttg cataagctgc catattttct tgcatattct gaatcaaaaa
     2161 cggatctaac aatgaacctg atattactgc ttgatggata ccaaatccaa aaaatagatt
     2221 agcaatagat gtaattaaca aaaatcctgg taaaccagtt gtaattttac ttaatggctc
     2281 tgtaactatc gtggtaatta gcttatttat atccatatta aacaattgaa tgattataaa
     2341 tgacaataaa gcaaacgagg taatcgtaat aatgattggg attaatacat taaaagactt
     2401 taaaacagcg ggaggaatat ttccggatag ctgaatctgt agtttcttat tattagaaag
     2461 tttaataaat aattctgtag ccgctaatcc aacaaatata cctacaaaca ttcctgaagc
     2521 tcctgtatag gatataggta tcacacccgt cacttcaaca gctttatccg cattttcagg
     2581 agtaaacatc atctgcatag gtgttaatac aacaaatgtc gaaatagcaa ctaataccgc
     2641 tgcaatatga tttgtataat ttctgcttgc acacatatga taagatactg ctgctacaac
     2701 taataatgta gttatgctta atgtaccatt ggcaattgaa gtaccaattt gttgtaacgt
     2761 ggtcaatgta ctagtatcga caatttcccc catgaatcct gttggttcta agatcactga
     2821 attaataagt gtcacaaatc ctgctaacat cataaatggc ataaatgtag caaacgcatc
     2881 tcgcaaagtt cttaaatgga tctgattccc caacttagtc gcaactatac caaatttttc
     2941 aaatacaatg tccttcctgc tacttttgcc catatttttt ctcctttatg cttattgtaa
     3001 tcgattactt tttccaccca aataatacat cacttatcaa aaaaagtaaa tacttttaat
     3061 taaatatata tatctttttt agtataaaaa aataagctct gaaaaaataa ttttcccgag
     3121 cttatttttc aacaaaaaca gcttcaaaaa caaagtcttg atataaatgt ctcgataccg
     3181 aatactcgaa aggtttacca gacgatagag caacaacttt gtctatctca atcataaatt
     3241 cacctggatc tatttttaat atttttgcgt caaattcatt cgcagtatct cctttgatac
     3301 gtatgtgcga agtctttatt tccagaccca gttcatttgt gatataagca tatacagatt
     3361 tctttaaatg ttttggttcc aagcctggta tgactgctaa tggcatgaat gtttgctcaa
     3421 tcgagtatgg ttgacaatca ataaaacggc ttcgtacaat attatataca tagtctttta
     3481 cactgatact taatttatca gctacttttt tcgatggaag ttcaattgag aaagtatgga
     3541 tttctgaatc tacgtgttct tcaccaacca cgctaaacaa accttcgttt ggaccaagaa
     3601 ctcgtgagtt atcaattggt gttctgacga cttcagtccc atacccactt ctacttcgca
     3661 aaactccttc ggaaacaagt aagtctacgc ctttctttac tgttaacttg cttgtatgat
     3721 aaataactgc caattcatct cctgtaggaa gtttctcacc aattttatac tctccattta
     3781 caattttttt ctttatatct aagtaaattt ccatatactt cgcaattttt ttcaatggtg
     3841 accctccaat caaaaacata tcttcatcta tactttaaca taaataaacc gataaaatcc
     3901 acatcaaaat tatacacaca ataaaaaaga tatatatatt taaacaaaac tatttacttt
     3961 aagttgtaag cggtgttatc attaagtgga aacaggaggt aaaaaaatta tgacaactat
     4021 gaaaaagcta acttttccag atgatttttg gtggggttcc gcttggtcag ctgagcaagc
     4081 agaaggaaaa ggagaaacag gaaaagcaga gactatctgg gatcgctggt ttaaagaaca
     4141 accttaccgg ttttatcaac gaatcgattc ctctattaca accgatcaca tccatcaata
     4201 taaagaagat atagaactaa tgaaaaaaac tgggcataac tcctttcgcg tttctatttc
     4261 ttgggcacga atgtttccaa atggcggtac cggaaaagta aatcccaaag ccatttcttt
     4321 ctatcgaaaa ttattttccg aaatgaataa taacggaatc aaagtatttg ccaacttata
     4381 tcattttgac atgcctgcta ctcttcaaga taaaggagga tgggaatcac gtgaagtagt
     4441 tgatgcttat gttcattacg ctgaaacttg ttttaaagaa tttggtgact tagtttgtca
     4501 ttggtttacc ttcaatgaac cacttgggcc tattttaggt acttatcttg aagattttca
     4561 ttatccaaac ctcattgact ttaaacgcgg agcgcaagca gcattcttca ctatacttgc
     4621 acacgcaaaa gcaatacaag tatttaaaga actagctctt cctagtaaaa taggcgttat
     4681 tctaaatttg agtcctactt ttcctcgtag tcaaaatcct gctgatgtga aagcagcaga
     4741 aatcgctgat ttattttata cgcggagctt tttagatcct atggttaaag ggaatttttc
     4801 taaaaagctt atcctgttat tacaagaata taatcagctt cctgaagatt atacgaaaga
     4861 agatcttgta tgtatctacg aaaataccgc tcaaattctt ggactaaact attacgagcc
     4921 acgtcgcgtc aaatctcgtt cttctatggt ggatacatct agtccatttt taccagagtg
     4981 gtttttcgaa ccacatatca tgcctggacg acgaatgaac gaataccggg gatgggaaat
     5041 ttacgaaaaa ggaatttatg atttgtgcat ggatatcaag aaccattatg gaaacatcga
     5101 agcatttatc tcggagaacg gaatgggcgt tgcggatgaa gaacgtttca tggatgatac
     5161 agggcaaata attgatgatt atcggattga gtatatcaaa gatcatcttg cttacttatg
     5221 gaaggcaata aatgaaggat gtaacattaa ggggtatcat ctttggacat ttattgattg
     5281 ctggtcatgg atcaacgcct ataaaaaccg atatgggctg gtttcactcg accttactac
     5341 tcaaaaaaga acaattaaaa aaagtggcga attttacaag caattaagtg atacaaatgg
     5401 atttagatac gatgtagact tgttagttga ataatattct aaaattccac ttgaagtgaa
     5461 cacattagaa aacaagaata atgagaaata ccaataacaa atactttttc ttcatacttc
     5521 atttatactt gtcagtataa gagactgtga caaatgtagt gatcctcaga agttaggtct
     5581 ggaaatctaa cttgagaaga tttttttaaa ctacgtccag tcttttttat ttgtttaaaa
     5641 ttgaagttga caagtcttca ttaaaaattt agaatattca caagtttgac gacaattatg
     5701 aaaatttatg tcgtgctaaa ggagttttgt tattggatga aaagttagat ataaaaactg
     5761 cgatcaaaga cacgttacct accgtttttg gttatatcgg tattggactt gcatttggta
     5821 tcgttgggaa agctgccggg tttcatccgc tggtcgtcac gttgatgtcc ctgctgatct
     5881 atgctggttc tgcccaattt atcacggtca gcatgcttgc tagccatagt ccactgctct
     5941 ccatcgttct ctcgaccttt ctagtcaatt cccgaatgat tctgatgagt atgacgattg
     6001 ctccttattt caagaaaaat cggctgcttc aaaatctgct gattggcaca ttgctgacag
     6061 atgaaagttt cgcactggga atgaataaat tgaactatac tggacaaaag ttaaactttc
     6121 gttggatgaa tacagctaat tggatttctt atttgacgtg ggtgggttct tctcttgttg
     6181 gcgcactttt agggaatttt attactgatc cgaaaaagtt tggtttggat ttcgccatcg
     6241 tcgctatgtt tatcgggtta ctttatcttc aagtcatttc tgatagaaac acctctaaac
     6301 gattacagtt gatcctgatt ggtctcactt tgattctggt atatgtcgga ctgattttta
     6361 tcccaagtaa cttagtgatt ttagttgtaa cactgattgg gtgcggattg ggggtgtgga
     6421 tcaaacatgc cttcttttga gtttacattg ctgactattt taggttgtac tttagcaact
     6481 tggctttcta ggatcctacc atttgtctta ctgaaaaaat tcgatttgcc gcaaccgttg
     6541 cttgagtatt taagttttgt cccgatcgtc attatgtctg ctttatggtt cagcagtcta
     6601 tttacccaaa atatcggaca tctgccgcag atcaatctcg aaaatgcttt ggcttcagtt
     6661 cctacacttt tagctgctat tctttcaaaa agcttattgg tgatcgtctt ggtaggaatt
     6721 ctttcccttt cgttgattcg cttattataa ataaaaaaac aagagcttat ggcaaattac
     6781 tgtcatgcgc tcttgttttt atcaaagtca aataagaaaa aaatcggcgt attcttgctt
     6841 atccgttgaa cggaccacta acaacgactt ttcctaatat atgtcctgtt tctacgtctt
     6901 tggttgcttg tttcaagttc ttcgcattca tcccatctga atagaccttg ctcaatgtac
     6961 tgcggataat cccttcattt gctaaagcag caatgtgcgc taaagcttct ccttgcgttt
     7021 cgatttcata gttatagtct gttttagcga acatatactc ccagtcgaag ctgatagatt
     7081 ggtttttcca aacacctata tctaacggct ctttgatccc tacgatcgtt cccacatgtc
     7141 caaatggtcg gacaaggtgt ttgatttgat caaagtagcg ggtaatatcg aataatacag
     7201 cgacatactc tacttgatcg attcctaatt cacgaaaact tttacttaag tcgtgatgat
     7261 aatcgattgg atagtctaca cctgtttttt tcagccattc aaaattcttc ggacttgcag
     7321 tcgcgtagac ttctaggcca gcccaatgcg ctagttgatt caaaatcgaa ccgacgcccc
     7381 cagctccgtt gatcactaag atttttttcc cgcggttggc attttcttct ggagtcagac
     7441 caaatttttc aaataacaat tcataagcgg tcaatgaggt caacggcaag gctgcggctt
     7501 cttcatctga aagatttttt ggtgcaagag cgacaatacg ttcgtcaacc agttggtatt
     7561 cttgattgct tcctgctctt gtcgttgtac ctgcgtaaaa aacgcgatcg ccgacagaaa
     7621 atttttgcac ttcatcacct acagcaacaa ctttcccgac tccatcaaac cctaagatac
     7681 gtaaagcatt tcttatcccg ttatcttggc gaagtttcgt atcgacagga ttaacagata
     7741 ctgcgttgac ttttaccaga agatcccgtg aactgggtac aggtatctgt tctttttcat
     7801 caataaagct ttttggatca tcgatcgaca acccttcata aaaaccgact accttcatta
     7861 attccttttc tgacatacga attcctcctt agcttcatca agttggagca tccatacagt
     7921 tttcatttca atatatatag tatgctattt gttccacttt tattcatcat aattattctc
     7981 ttacttaaag taaactattt gcactttttt ggttaaaaaa gaggttgcga caagactttt
     8041 gtcacaacct cttttaaacg gtgttcaatc aactgaccct cggtattcgc tcaaaaaacg
     8101 acaaaatatg aggagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt
     8161 ttcacgacct ctaattcacg gtgttcaagc aagaaatcat tgttcactga aaagcgttgg
     8221 atgttctttt tcaaaggtgt ctaagatctc tcgtacttca tcagtagatt tcgtattcat
     8281 caactgaact cgcaagtcat ttgctcctgg aaatcctttg atatagattt taaagaaacg
     8341 atgtagtcct gtgatggaac gcgggatgat ttctgaataa tgatcttgca gatctagttg
     8401 cagacgaagt agtccgatca gttctttttc tgtatgttcc ctcggttctt tttcaaatgc
     8461 ataaggattc ttgaaaatcc cccggccaat catgatgcca tctacgccat atttttcggc
     8521 caattcttct cctgtctggc gatctgggat atctccgttg atcgtgatca gtgtttgcgg
     8581 agcgatttgg tcacgtaaag caatgatttt agggatgact tcccaatgtg catctacttt
     8641 actcatctct ttacgcgtac gcaaatggac agaaagattg gctatatctt gatgaagtag
     8701 gtgactgatc cattcttcca tctcagacat ttccgtatag ccgatacgcg tcttgacgct
     8761 gacaggcaaa ccgccagctt tagccgcttc aatcaattgt gccgctactt ctgggcgaag
     8821 gatcaagcca ctgccttttc cacgttctgc tacattaggg actgggcagc ccatgttgat
     8881 atcgattcct tggaagccca tttctgccat agcaatgctc atttctctaa aaaattctgg
     8941 cttgtctccc caaatatggg caaccatcgg ctgttcatct tctgtaaagg tcaatcttcc
     9001 tcgtacactg tcttttccat ctggatgaca gaaactgtct gagtttgtaa actcagtaaa
     9061 gaagacatcc ggtgctgctg catgctttac gacatggcga aatacaacat ctgttacatc
     9121 ttccattggt gctaaaacaa aaaaaggctt tggcagctct ttccaaaaat tagtagtcat
     9181 ttatttgtta ctctccattc tatcaagcag tgaagtcgca atctttctca aaaacattgt
     9241 cattatacta ggaaacaaaa aaagaagcaa agtgaacagc ttaaaagatg tttctgattg
     9301 agcaaaaaaa gactgtgaca aaaatcttat cacaattcct tttccggaat aaatggtgtt
     9361 caaaagcttg catctgcggt aataagtcca accaaacgaa aaataggagg agctattttt
     9421 gtttggctgt tcttattact tgatgcagaa cagctttttc acaacctctc cactaaacgg
     9481 tgttcaatca gctgaccctc ggtattagct caacaaacga caaaatatga ggaactattt
     9541 tcccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc ttttctaact
     9601 tctcaatcct cttcctttat tgatcaaata ccaagtaacg gcgtacaaaa caacgatgaa
     9661 tagcacaagt acgatcatcg atgttgctac tggcacatcg attgttccaa ggaatccgta
     9721 acggaaaccg gagatcatat aaacgatcgg attgactttc gaaacagctt gccaaaatgg
     9781 cggcaacata gagatggcat agaaaacgcc acctagataa gttaacggct gcaagacaaa
     9841 tgtaggcacg atcgatacat cgtcataaga ctgagcaaaa atcccgttga gcagtcctgc
     9901 taacgaaaac aagattgccg tcatcaataa tgtaatgatg accatgaacc atgaatacac
     9961 atgaagtggt acaaagaaca aggaaatgat cgttacgaga gagccgacga gaatactgcg
    10021 acccactccg ccaatcacaa agccccaaat gatcacatgc gtaggaacag gcgctaccaa
    10081 gatttcttcg atgtttttct ggaatttttg agagaagaag gacgaagaaa cgttggcata
    10141 cgaactagtg atagcagaca tcataatcaa accaggcacg atgaattcca tatatgaaaa
    10201 accacccatg tcaccgatcc gaccaccgat catttttccg aaaataacaa agtacaagga
    10261 tgtcgtgatc acaggcggaa ccagtgtttg gacccagata cgcaaatagc ggttcgtttc
    10321 cttgatagct aaacttttta atgcagtaaa ataaagatta aacatttttc tcctccgtat
    10381 gattattttc ttctgtgatt ttcaaaaaca gttcttctaa acgattcgac ttattcctca
    10441 tagaaagaac tttgattcct tgtcttgtca gctgatcgaa gattccgttc accccttgat
    10501 ttcgttcaac ttcgacagcg attgtctgtt catcttcaaa tgtacaagcg tatccttcaa
    10561 tcacaggttt ggtctcatat ggcgctaaat caaagataaa tgtttcaaat tgcagtttgg
    10621 atagaagctc tttcatacta gtattctcga tcagttcacc tgattggatg atcccgatgt
    10681 tgcgacaaag catttcagct tcttctaaat aatgcgtcgt caaaatgatc gttgtaccat
    10741 tttcgttcaa ttctcggaga aactcccaca tctcgcgtct caattcaata tcgactcctg
    10801 ctgttggttc atccaagatc agcaaacgtg gttcatgcat caatgcccta gcaatcatca
    10861 gtcttcgctt cattcccccg gaaagcatac gtgcacggac atttctcttt tcccaaagat
    10921 tggactgctt caaatatttt tcgctgcgtt tcatcgcttc tttgcgagag acaccgtagt
    10981 agcctgcttg attcacgacg atttgctgga ccgtttcaaa gggattgaaa ttgaactctt
    11041 gcgggactaa tccaatctgt tgctttgctc ggactagatc cgtatccaga tcataaccga
    11101 agacattcac ttttccagat gttttattga ctaaagaagt aatgattccg atcgttgtag
    11161 acttcccagc tccatttggt cctaatagcg catagaaatc tccttctttc acggaaagat
    11221 cgattcctcg caatgcttcg accccacttc cataaacctt tttcaaatta tttatttcaa
    11281 gcgcatttgc catttatttc ctatctcctt atagacatga ttctttattg tatcatggaa
    11341 tacagcagat gaaaaaacaa cttggttcca gcgaaaaatc aggttgctgg gctcaggaaa
    11401 atctcctaat gaaagacatc aatcggacga agtcagacaa ccttttcaga aaaaacaaat
    11461 cgaagataaa ggattactat tcatatgtgc aacaaaagga gcgtgagaca aaagtaaaga
    11521 acacttttgt ctcacgctct aaacacgtat aaacggcgga agcaaaagcc aagatttttg
    11581 atccaataaa tactttcgat cacttcgcct atcccaatac atgccactgc cgcttttcat
    11641 caaataacgc ggcttccgtt tttgcggttt ctactaaagt ctctgggtaa tccaaaactt
    11701 tcagcaaggc aatcgcattt cgggtccttg aaggtccttc ttttaatttg aaatcaaaac
    11761 tgattccttt tccttctgtt acttgttctt caaagtggac attctcacaa taattcttta
    11821 aaatctctgt caattcgata tcatgtgtgg cgacaaatgc taaagatgga tactccgcaa
    11881 gccaccgaac gactgaagcg gaagaagcaa tccgttcgat cgtatttgtc ccttttaaaa
    11941 tctcatctac gaagcagtag cagcgttctt tggaagccac ttggtccaac aaacgtttga
    12001 tcgatttgat ttctgaaaca aaataactgt cgccttcaaa taaatcatct tcgattgcca
    12061 tggaagtcaa cacatgtcca ggttgcaggg taaactgttc tgcaatcgct gtttggatcg
    12121 tctgtgctag aatacagctg atggctatac ttttgacata cgtagatttt cctgatgcat
    12181 tggaacccgt gactaatgta ttcttctgcc agttgaccgg attcactacc gcttctttta
    12241 acaatggatg atagatatct ttcgctgtca caccgccctc agtaaactct ggtcggcaag
    12301 tgatgggcat ataagtacgg taattcaata ttgcagcggc tacttctaat tctcccagca
    12361 attcccacag cttgatggct tcagttgaat gcttttctaa tttagtgaga acgaaatgat
    12421 aggagataaa tggcagcatg aacatgatgt tgacatattc aaaaatcaac tctgcttcac
    12481 tcccactctt catacgaaat gaaaaaccta atttagggat gtctcttaat ggtttagttt
    12541 gctgtttcag ctcttcttga agtggtgtcg gcagttttgc tagctgattg gcggctgaaa
    12601 tcgttgaaac caaataactc atgctattca gctctgtttc tagtgtttgt ttcttcacta
    12661 gataatagac cgtattgaat actaacccac cgattgccaa atagattcct agtacttgtc
    12721 ctaaaagaag caaacccaaa cccaccagcg gaagcaagcc aagaaaaata aataaaccta
    12781 cgcgtccaat ctttttactt tttccatccg ctagatattg ttttgcaaaa ttatgatctt
    12841 tttttcctaa acgagcgaat tgatattgga ttttttctct cagttgagga ttttcctgat
    12901 aaaaagcaat cagtttttct aactgctgat cttcaccaaa atcaaagctg cgtaaacgtt
    12961 gatacaacgc ttctgaacct acactagaat aggtactgtt gattccttcg aatacttcga
    13021 acatatccag gtcataccaa gtaagatcat cgatttcgct atcccatgaa cggaacttct
    13081 tctccgtgag ccatgcttcc ttcaagcttt cttctttatc aaatctcggt tgataaggaa
    13141 ttttttccca tttgctacga actgtttcct ttaatttcaa acgtgaaaaa atgtctaaag
    13201 caactaataa aataacagct gcaataataa ttaaaacgat aaattctctt tgacccatat
    13261 ccctctccgt tcctttattt gttagcttta gtatagcact gttgcgctat ttgaaaagag
    13321 ggtaaaaaaa cacctttcaa aataaaaggt gtttttttct tgtatattac atatttatct
    13381 ctcatttatc aaaattgaca aataatcata gggaggaatt gttgttaatt cttgtttatt
    13441 ctccagtgca ttgacaactg tcccaaggga aaggatagcc tcaggtacta ttttttcttg
    13501 ttctgttgga ttagctaagc gaagaacaaa tccttgttca tgaaaataag aaggataaat
    13561 cgatgataca attaagtctt caggtaattc aatcaatgaa aatttacgag gaacatcaag
    13621 ttcattttgt aatggccaaa tcttgttatc taacctgtga ataaatacat tcagtttctg
    13681 cttttgataa gaaatagatt gttctaaccg tttttctgcc tgttttgcca ctttgaactc
    13741 attaaatctt ccttcttcta cattaaatcc aaaagtgact ttatactcac ctatctcttg
    13801 agctagcggt gtttccatca tgacatgccc ttcatttgtc gtatctcctg aagctcgccc
    13861 aggtcgccaa gcaagattag gttttccaag ttcccctgtt gttgaaaata aggttatgat
    13921 taattgattt tctatacgtt catactcttt taaaccatct gcataaaacg taaaataatg
    13981 atcattttct gccacagaga cactcttatc gaatatttct aaattaacag gtttctctac
    14041 catagtttct gaccaattcg gaggaatgac atcaggggta ttttcaataa atccgttttg
    14101 aatttgtgca attgattttt cagatttatc taaaacatta attgctaagc gcatacgatg
    14161 cgagtaaaca gtattatgaa ttttgagtgt gccttcaacg atttgacttt ctcccagact
    14221 gaacgatatt tcataagata tttcttccat ttcgggtttt tcagataaac gatcttttaa
    14281 atctttagga agttgagctt ttccgtaaac aactaatgtt tcttgtaaag aatctttata
    14341 tactttagct gtttctaatt ttagagatag ttctgtatct ccttctaatg gtgaataatc
    14401 atacgtatcg ccatcatttg ctgaatcgat caaatgaacg aaatcaagat attgtctatc
    14461 tccaactatc aaattcaatt gcccatcttt aaaagaaagt ttatatttat tgttacttat
    14521 ctcagttttg tctatctcga ttgctgtttc taatttttca ttatttttct caaattcaac
    14581 aacagtgtat cctagtgctg gcacatttac atttattttt atgtcaagtt cataataagc
    14641 tggttcatca aaatattcga aacctgtagc aatcatccga taagcatttt tccgttctgg
    14701 aaaataaact tctttttcaa tgatattata gggactacct ttgaagtgta ttttctttga
    14761 atcagctact acatgcacga ttttcgatcc actataattc tcagtcgttg tgttgaaaac
    14821 aaggacttca ttcgatttta gctttaatgc atcagccatc cgttttacaa taaggttttc
    14881 gattccgtca gctatctcat tagcttcttt gattcgatgg aaaatatctt ccgcaacatt
    14941 atctgaaaca cagccaccaa tactatcatg agcctggttt tgcaaaatct ttttccataa
    15001 ccgacgaagt aggcctttac tgatatggat accatttctt tctgcaatca gcatgagcgg
    15061 ctcaactcgt tttagaattt tttgttccaa tttaaaattt tctattttca tttttgttct
    15121 tactgagcca atagaacgat gaacacgaga gtaaaccggc tgacgaagtt cacctttata
    15181 ttcaggtaat tcttttttgt ttctgataac ttctacataa gaaggataat ctgaaataat
    15241 attgtggaat ttactgtatt tattcaactt ctctacgact tgatcaaaat ttaaaatcat
    15301 tgacttttga tctacacccg aaggtactaa aatatctttg ttttttcctt gcatatgaag
    15361 catttcaact gcttcatcca acttttcttt tgcaaattca ggaatatctt taattgcgtc
    15421 taaggtcatc attccagtca tataaccaaa tggaaaattc atggcataaa caaatttatc
    15481 tcccaatcct ttccagataa aataaggaga tggaaccatc gtttcaaagt ttaatcctcg
    15541 ccaacacatg aaattatcga tttctacttg atgcaaaagt gtaggcaaat tcgcattgaa
    15601 cccaaacgtg tcaggcaaat accctaccat cattggatct ccatatttaa ggatcgtatc
    15661 actgattcca atcattaagt ttcttaaaat tgattcagca tccactaata aggcatctgt
    15721 ttgtgcatac cacggtccca cgaatagttg tcctgttttc atcagtcgtt ggataacctt
    15781 aagcttttgc ggattgatct ccaaatactc atcgacgatt gaagtttgtc catctaaaca
    15841 aaagtttact ttagggttcc tttccaattc atctagaact tcagtaaaga cctgatcaga
    15901 caatacgatg gcatcttcat ttgtaaaata ccattctctg tcccagtgcg tgtgttgaat
    15961 tatatgtgca tttaccatat cagattctcc tactttcctt cttctactga atttacttgt
    16021 tgttcttttt tatacttgat ggattttagt gcattgacca ttaacgctgt aaccactccc
    16081 ccaataacaa ttgatactaa atataaaggt atattcgtaa caaaaggaat tgccataaag
    16141 gttgaaagca ttgtttcttg agtaacacca aaaaatccat ttagaccaca tgctactgca
    16201 gtgcccacca cgatgcttgg tattactcgt aaaggatctt tcacggcaaa cgggatcgtc
    16261 ccttcagtaa tccccacaag gcccataatc atagctgtct ttgcattatc tcgttccgat
    16321 tcatcataaa gttttttgtt taaaattgtt gctaaaaaca ttccaaatgg cggaatagca
    16381 attcctaata acatggctgt actaggtcca aagcttccgc ttgaaaaaga agcaacccca
    16441 aaagcatatg cgattttatt gataggtcct cccatatcaa acgccatcat tcctcctaaa
    16501 atagccgaca tcaaagcagc atttgctcct gacatgcctt ctagccaatt agtcagtcct
    16561 gttgtcattg cttgaatagg cgtagctagt acataccata atatgattcc aacaactaat
    16621 gtagtaacaa aaggaatcag cataattgat tttagactaa taacttgcat cggtactttt
    16681 acttttttca atgcattagc taaatagcca caagctaatc cagcaaccat tcctccaata
    16741 aatcccatac caagattttg acacatcatc ccagtgataa aagctggtgc tagaccggga
    16801 cggtcagcaa ttgaatatgc gatataggct gaaatcatcg gtacgataaa ctgtaatccc
    16861 gtctgaccaa tcattcgcag gactccccag aatgtatccg tctggtccca aacacctgtg
    16921 ccaccaaaaa tgactgcaat agaagttagt aaccctgctg ctacgacaag cgggatcata
    16981 taggaaaccc cactttggaa atgatttaga atttctcttc cttgtttctt gaattccatt
    17041 agtaactccc ccacgatata ttttttattt gttaattaat gcaattgctt catcaatcgt
    17101 ctcttcacca tcttttacta cctctgaggt ccctactgtt aaaatcggtt taccgtcaaa
    17161 gcgacctcgt tctgaaacat ttgtatctac tgcaaatatg acaacatctg cctcggaaac
    17221 atccgaaatt gaaagtttgt tttctatccc catagccccc tgtgtttcta ctttaatatc
    17281 taaccctttc ttcttcgcaa acttttctaa attagctttt gccatataag tatgggcaat
    17341 ccctgcgata catgctgtta ctgctactat ttttgtcata tgaaattcct ccttttaaaa
    17401 tgatagagct tttaccaatt cttttttatt tctcgaatct tttattcttt taacaaactc
    17461 gtcatccatc aatcttccag ataattctgc taaaatacgt aaatgattag tacctttatc
    17521 agtgtctttt attgctaaca aaaagacgag atcaactggt tgatcatcta atgcgcccca
    17581 ttcaacagac cgctttaact tggctacagc cactgttgat tcaattactg ctaggctttt
    17641 gccatgagga atggcgatat ttttcccaat tcctgtggtc atatggtttt ctctgtcaaa
    17701 tacgtctttt tgaaattgtt tgtggtcaga cacaaaccca ttagtctcta acaatttcga
    17761 taatttttcg actacacttt ttttatcaga tgcatttaaa tctatcacta tattatttat
    17821 attgattttt tcactgatca tttataagcc ttctttcaat atataaacta atttttcaaa
    17881 cgacgaactc gtttttaaat ttgctaataa ctcatgattc gaagcgattt cattgaatgt
    17941 ttcataaatt ttattcaatt caggttttac tttttcatta agtgcaaaaa agaaaacaga
    18001 atgaacaagt gtcccatccc aatcaattcc ttctggatta acgtagacac agattactgg
    18061 cttttttata aaatctactt cgatatgcgg catagcaaaa tcattcatcg ctgttgaaga
    18121 tagtttttct cttttgattg ctccctctag tatcccttct ttcgcgtaat tttcttttac
    18181 caattttttg gtaattatat ttaaaacgtt cacttgatta tcctttattt ggtgggtaaa
    18241 aaagcaaaat cgtttatcta ataaatttag aaaagcatct tctgtttgtt catttaactg
    18301 tagatactgt tttacttttc tgacatctgc ccctaacatc aaaggactaa caacaataac
    18361 aggaaaattt gtattttcaa tcggaatcgt gcttataaca agttcatcag tgacttttct
    18421 atcttgtagt tcattgatgc ttagtacatc ttctatctca accatatctg caaaaccgtt
    18481 atttattctt tgctctaata attttgatgt tccatatccg ctactacaaa ctaatatcac
    18541 tttcgttttg tcaggtttgt aacgatccaa aagtgattga atatggagtg ttacgtaagc
    18601 gatttcatct tcattaaaat gtatacagaa tctctcttcg atttcctcta ataaatctac
    18661 acttatcata aatgaccttt taaaagaata tttgattttg tccgtataag ggttatagat
    18721 atttactccc aatttgagtc ttttaactgc tgcattgaga tgtaatacta gattattgat
    18781 caattcttca tcaggataaa attcatttaa tttaattctt actaactctt gtagctcaac
    18841 acccatatct aaataggaaa gcttcgtttg atctaagtcg tgattcatag catttttttc
    18901 aatcgaagta atgtgaatgt caacataagc ttgttcatct attggcacaa taattgaaaa
    18961 tgctttttca atcattttga ttaaaataag tgtattcttt gagatttctt cttcagaatt
    19021 attactacgt gataagaaat tgcttgtttc aatcctttct atcgcaatag caaggtggat
    19081 agctaaagtt tgaaattcat aatctgtaaa tttcaattgt gtcttattca tgtatcgatt
    19141 aagcaattcg gctacttttt tcaatatgtc cttatttaag aaattattcg cttcaccaat
    19201 gaaattgata ttcaagtcta agagatctgt tttactgtta gatgctgtaa agccacccca
    19261 ataatagttc acaacttctg acatcaacct tcttttactt ttttcatcag ctttgatgcg
    19321 cacgccattt cgatctgaaa ctaaggacat cccatgcttg tttagtcttt ttctaacatc
    19381 tttcattgtg ctttctaccg tcgacctgct cacgtataat tcgtcagcaa gattttgaat
    19441 ctttagagaa tcattagtat tcaataattt agcaaacaca taagttagac ggtcctccgg
    19501 agagtctgcg atattgattt tatgactgga taataaattt cgaagtgttt ctttttttcc
    19561 aataagcgaa acgccttttt taggttgaac caacatttgt acatctggca ttttttggat
    19621 tatttctttc aaaattaaaa tatctttgct aattgttttc gtagatacat ataattgttc
    19681 tgataattct ttgtaagttg tgtgctcatt ttcaatcaaa aagtatagta ttttcatttg
    19741 ccgttcgcta aattcgatgc ccattatctt cacctcctga atacagctta agtgtacaat
    19801 tattatctct attttcatac agaagaaagt tcttgattaa tgtagaagtt tctaatattc
    19861 ttgattattt caa
//
LOCUS       DACGDM010000041        19657 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.042, whole genome shotgun sequence.
ACCESSION   DACGDM010000041 DACGDM010000000
VERSION     DACGDM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.042"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..152
                     /locus_tag="IXR05_001608"
     CDS             <1..152
                     /locus_tag="IXR05_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260112.1"
                     /translation="NFAKNQGYNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIY
                     MKKTL"
     gene            complement(230..763)
                     /locus_tag="IXR05_001609"
     CDS             complement(230..763)
                     /locus_tag="IXR05_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAQ4260113.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(857..2035)
                     /gene="mutY"
                     /locus_tag="IXR05_001610"
     CDS             complement(857..2035)
                     /gene="mutY"
                     /locus_tag="IXR05_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAQ4260114.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(2028..2825)
                     /gene="recX"
                     /locus_tag="IXR05_001611"
     CDS             complement(2028..2825)
                     /gene="recX"
                     /locus_tag="IXR05_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAQ4260115.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            2932..4314
                     /gene="rlmD"
                     /locus_tag="IXR05_001612"
     CDS             2932..4314
                     /gene="rlmD"
                     /locus_tag="IXR05_001612"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4260116.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4488..5066)
                     /locus_tag="IXR05_001613"
     CDS             complement(4488..5066)
                     /locus_tag="IXR05_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAQ4260117.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5388..5858
                     /locus_tag="IXR05_001614"
     CDS             5388..5858
                     /locus_tag="IXR05_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAQ4260118.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLTMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(5966..7192)
                     /locus_tag="IXR05_001615"
     CDS             complement(5966..7192)
                     /locus_tag="IXR05_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAQ4260119.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(7946..8146)
                     /locus_tag="IXR05_001616"
     CDS             complement(7946..8146)
                     /locus_tag="IXR05_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4260120.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8280..8888)
                     /locus_tag="IXR05_001617"
     CDS             complement(8280..8888)
                     /locus_tag="IXR05_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAQ4260121.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(8973..9443)
                     /locus_tag="IXR05_001618"
     CDS             complement(8973..9443)
                     /locus_tag="IXR05_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAQ4260122.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(9491..10405)
                     /locus_tag="IXR05_001619"
     CDS             complement(9491..10405)
                     /locus_tag="IXR05_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4260123.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10551..11354
                     /locus_tag="IXR05_001620"
     CDS             10551..11354
                     /locus_tag="IXR05_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAQ4260124.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11532..12479
                     /locus_tag="IXR05_001621"
     CDS             11532..12479
                     /locus_tag="IXR05_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4260125.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(12547..12840)
                     /locus_tag="IXR05_001622"
     CDS             complement(12547..12840)
                     /locus_tag="IXR05_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAQ4260126.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(12868..13533)
                     /locus_tag="IXR05_001623"
     CDS             complement(12868..13533)
                     /locus_tag="IXR05_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAQ4260127.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(13673..14305)
                     /locus_tag="IXR05_001624"
     CDS             complement(13673..14305)
                     /locus_tag="IXR05_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260128.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(14312..15379)
                     /locus_tag="IXR05_001625"
     CDS             complement(14312..15379)
                     /locus_tag="IXR05_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4260129.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(15376..16107)
                     /locus_tag="IXR05_001626"
     CDS             complement(15376..16107)
                     /locus_tag="IXR05_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAQ4260130.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(16276..16755)
                     /gene="greA"
                     /locus_tag="IXR05_001627"
     CDS             complement(16276..16755)
                     /gene="greA"
                     /locus_tag="IXR05_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAQ4260131.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(16891..18066)
                     /gene="mltG"
                     /locus_tag="IXR05_001628"
     CDS             complement(16891..18066)
                     /gene="mltG"
                     /locus_tag="IXR05_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAQ4260132.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            18270..19439
                     /locus_tag="IXR05_001629"
     CDS             18270..19439
                     /locus_tag="IXR05_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4260133.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT         5928 a         3952 c         3145 g         6632 t
ORIGIN      
        1 aaaactttgc taagaatcaa ggctataata cgattttatt aggggcacag tccacagctg
       61 aaacttttta cgaaaaacta ggatatacag cttacggcga tccttttgaa gatgctggca
      121 tgcctcatat ttatatgaaa aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca
      181 gcaagctttt gagaaaaatc tctcactggc ttactgttct tttttgtgtt tacttacgcg
      241 acaattgctt gtaacggtta taccaaatat caatatagcc ttccgagaac gggccatctc
      301 cattattgat ccagtcaacc agaatcttca cattttcttt taggatgaag tcaatatcgt
      361 tcgggtaatt catcattttg ctgtgcatct catattcatc gacatccaat agtcgtttct
      421 cgccgtcagg aaataccttg atatccaagt catagtcgat atatttcaag gcctcatcgt
      481 ccagcaaaaa aggtgaagct agattacaat aataggaaac ccccttttct ctgatcattg
      541 ctattacatt gaaccagtat tttttatgaa aataaacaat cgctggttcg cgcgttaccc
      601 atcggcgtcc atcagattca gtgactaatg tgtgatcatt cacgccgatc atagagtgtt
      661 cgcttgtttt taataccatg gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt
      721 aactttggat cgtcacaaac tctccttctt ttggaactcc catagcaacc cttccttaag
      781 cagcattttg tgctttgtgt ttgggtgttc attacaccga catcataatt attatatcaa
      841 taaaaatgag ctttgcctag aaaggattcc tattgtttcg atttttctct aactgatcta
      901 ccagtttcat ttggacctta ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact
      961 tcgaagtttt gttctcggta aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa
     1021 ggagaacatg ccatttcaga tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct
     1081 gccaaacaaa gagttcctgc ttttcaaatg ggagattttg ctcttcttct gctactaggt
     1141 catcaaacag atcgatttct ggctttgttt cccattcttt tttcaatcgc tcatactcct
     1201 cttgtgtcac ttccatcatt ggaaatgtcc acatattcgc cagcaatttt tggctatctc
     1261 tttcttcaaa ataatacgct ccagaatgat tttgaagagc tgcactgata taataaacgt
     1321 cttttggctt tgcttttttt gtttttacag gaaaactcgt ttggattcct cgtttgttag
     1381 ctaaacaaaa ggcttggatc ggacaagtct cacactttgg agaagttggt gtacagatag
     1441 ctgaacctag atccatcatt gcttggttga attcacctgg atgcttttca tcaatgattt
     1501 tccgcatcgc ttcatcaaag attttcctgc tagaagcttt tgcgatgtct gcttcaatgc
     1561 aaaacaatct gctgactact cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa
     1621 atgcgatact tgcaatcgcg cctgtcgtat atggtcctat tcccttcaat gagctaattt
     1681 cttcaggcgt ttgcggcatt tccccatcaa attctgacat gatctgttta gcagcagctt
     1741 ggatgttccg ggctcttgag taataaccaa ggccctccca tgcttttaaa agcttttctt
     1801 ctggagcatt tgctagctct tcaattgtag gaaaccattc catgaaacga taaaaataat
     1861 cgatcactgt gtctactctg gtttgctgaa gcatgatctc agagatccag atacgataag
     1921 gatcacgatt atagcgccaa ggcaggtttc ttttttcttg ttcataccat tgaatgaact
     1981 gatcttgaaa ttcttttgtt tctttatctg tccatttttc ccattcttta ttcactttcc
     2041 tcttcctttt ccgtaatgaa tcgctggatc atatccaaat caaatccttt ttgatataag
     2101 ctttgcttta cttttagatt tcttttttta ggttcaaacc ttaaatttct tcgccatagt
     2161 ttatctcctt gtttgactaa ataatcatat tctatttctt gatctgcttc ttgcggaaga
     2221 tcagctatcg cttgttggat cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg
     2281 atttttctca ataattcttt ttggcttttt ccgtgatttt ttccaaacgc tttttcggct
     2341 gtctgatgtg cattttgaac ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg
     2401 atttcaggtt tcaaaccttt ttgctgcatc tgctgcgcta atttctttgg tcctttgtca
     2461 cttaagcgca tattcgtgcg cacataactt tccccataga ccaaatcatc gacaaggtcc
     2521 aattctttta agcgggctac gattttattt cgatcttctt gaaggatttc cttttctttt
     2581 aagtatgttc ggatttcttt ttccgatcgc aactgataac ttaagtaatt cattgctagg
     2641 tgaaaaccga aatcagctcc gctactcttc ttgatctctt ggatagtttc ttcgtctaat
     2701 tcccgtcctt ttaataatcg atagcgtact aatacatctt cagatacttg taaagcttct
     2761 ccttcagata aatctacgcg atagaaaggg cctttgcctt tactgattct cgtaacggtt
     2821 aacataaaca tcctcctcga acatatattc tctatcatac cacagaaaat ccccgtaatc
     2881 aggtattata tgttagaata aaccacagaa aaaagaaaaa gggagatact tatggcagaa
     2941 acaattgtca aaactggaca aacggttcct ttgaaaatca agcgtttagg cataaatggt
     3001 gaaggaatcg gttatttcaa acggttgatc atatttgttc catatgcact accaaaagaa
     3061 gaagtactag tgaaaatcac gaaagcaact cctcgctatg cagaaggaga attaataaaa
     3121 gtcaaaaaaa caagcaaaga tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt
     3181 ggctgtcaat tacaacactt agcttatcaa gctcaattgg attttaaaaa ggatctgctt
     3241 ttgcaagcat tggaaaaatt caaaccagca ggctttcgat cttatcaact tttgccgacg
     3301 atcgggatgg atgagccttg gcattataga aacaaagcac aatttcagtt acgaaaaaat
     3361 aagcagactc aaaaaattga agctggttta tacgaagcaa actctcatca gttagtccct
     3421 ataacagact gcttggttca agaacctcga acacaaaaag taatgaatac tgttgttcaa
     3481 ctattgaata aatttgatgc acccatctat gatgaacgga caaacagtgg aatcttccgc
     3541 acaatcatgg ttagaatcgg tgttaaaact ggggagttac aagttgtttt tattactcgc
     3601 agtaaaaaat tcccgcaaaa aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa
     3661 gttgtttcaa tcatgcaaaa tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa
     3721 acgatccact tatggggaaa agaagccatt gaagaacaaa tcaatgaagt gactttcgat
     3781 ctttctcctc gtgccttctt tcaactcaat cctcagcaga ccgaattgct ttatggcgaa
     3841 ggaatcaaag cattagatgt ccagcctaat gaaacgatcg tggatgctta ttgcggagtt
     3901 gggacgatcg gcttaagtgt agcaaaacaa gccaaagaag tacggggaat ggataccgtt
     3961 cctcaagcaa tcgctgatgc aaaaaaaaat gcggaaagat taggatatca caacactcga
     4021 tatgaagtcg ggacagcaga gcaagttctg cctaaatggt tgaatgaagg ttttcagcct
     4081 gatggtatca tcgtagatcc accacgtacg ggtttggata acgcattgat ccaatcatta
     4141 ttgaaatacc ctccaaaaaa acttgtttat atctcctgta atgtttctac acttgccaga
     4201 gatctggtta atttaagtaa aaagttcaag attgaatatt tacagtccgt cgacatgttt
     4261 cctcagactg cacgttgtga agttgtcgtg aagatgacga gactcgctga ctaaatgaaa
     4321 gaggttgtga aaaagtctgc cctgtatcaa gtaataagaa cagccaaaca aaaatagctc
     4381 ttcatgtttt atgaatactg tacttgtgac cgaagagtta acaggaggac actatttatt
     4441 taaaaaaagg gttgtgacat agtttttgtc acagcccttt ttgattatta ttggatattc
     4501 acgtctatca cttgataaaa tgcatttgtc gtatcgctga tattccatac tgctaaaatc
     4561 acattatatc cttttcgatc ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga
     4621 acagttgctt tgtcgtctat ttttgtgatc aattcaaaat cactaaattt caaaggttga
     4681 ttaggattcc aagttggttt ggtaatgtag taatcccaag tacttgtccg atgttgtgct
     4741 gttaaattcc aagtaatatt taatgttcct ggattaacca tgtttttatg ccatctgtta
     4801 gatgtctgtt catctaaagg ctcaaagccg ctgactcctg cactagcaat ttttccatca
     4861 atgaatgtat ttttggtagc ttcgatactt tgcggttccc attgtgctct tccgacattt
     4921 tgatttaagt ttcctgctgc tgatgttcct aggtatgcac ggcttcctgg agaagtaata
     4981 taaccatgcg caaaacctgg aatgctaaaa ccgaacaacc ctaaactaac taacccaata
     5041 aacaataacg tactaatctt tttcatgtag aaacctcctt catttgataa ccacattgta
     5101 aacgctttat tgtattaaca caaacattat gcttttataa ttttatgttg aagtaaaaaa
     5161 ggtgaaaaaa gtaagatgca gattataaca gaagtagacg agaaaagtac aaatagaaaa
     5221 catgagaatc aaatcatatg atctttttca aaaacatcat tcatataaac aaatgttcaa
     5281 ctttttaata acaacaatta tcaatttttt tcttacttca caaactaaat acaggtcttg
     5341 ctgtgagcct tcatggtaaa ctaatattat agaaaggagt tagtaaaatg aagatgataa
     5401 aagatattcg tttttgggtt tgtgttatag gaattgtcat attaggcttt ttatcagggt
     5461 tgcttagcgg aaatcccgga aaatattact attctttgca acttccacca tttgcaccac
     5521 ctagctggat atttgggccg atgtggacct tactgtatat attgatgggt atttctcttt
     5581 atttgttact taatcacaac aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga
     5641 ttcagttcat ttttaatttt atatggtctg ctctattttt taatttaaga aatattttca
     5701 ttgcagcaat cgatattaca cttttagtta ttttcttgtc agtgcttatg tatcagttgt
     5761 ggctgcatca tcgcctgaca atgtggctca tgattcctta ttatttatgg gtactattcg
     5821 caactctatt gaattattca atttattttt taaactaagc gctaaaaaga gacgtcctgt
     5881 aatttaacac atagaaaaag tgccacctaa gttagatttt ttgtctaatt taggtggcac
     5941 tctttattaa ccaaactatt tttttctagt acccacttgt tgttccatac tcattattct
     6001 ggtcataacc ataaccattt tgttcctgtc cagcgtaagg atcataactt tgagtatctt
     6061 gacttggtgt atagtactga cttgtatctt ctgtttgctg ataataggta ttcggatctt
     6121 ggtactgatc atatgtgttt tctgaatagg aagaataatc ggtgtaccct tcactattcg
     6181 atccatcacc gtttgtcgaa tcgccatctt ccgaatcatc aaagaacatc attgaagcat
     6241 tctcattttt caaattaggt aatgtatcgc ttgtttttat atttaattgt ttcttcagtt
     6301 cattttggat cgaaagaaga tcattttttc ctaaaatttg atagtagata tcattgatca
     6361 tttgtccttc gccttgcaac tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg
     6421 tcgctacatc aagcatgtca tcccaatcta agtccgtcgt cacattgttc tcaactgctt
     6481 ttaaaatttt tctataattg cttacgccat ctaaacttaa aactttattg acgattttcg
     6541 tcactacttc ccgctgacga cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca
     6601 ttcgagaata ggctaaacct ttttctccat tcaatgtttg ttcacctact ggtacatgga
     6661 caccatccaa agtaaagtca attttattat tcactttgat gccaccgacc gcattgatca
     6721 aatcttccat gccatccaaa ttgatcgtta cataatgatc aataggaata tcgagcagtt
     6781 gctcaattga atccatggcc atttcgacac caccaaatgc gtaggcatga tttaatttat
     6841 ctaccgttcc ataacctacg atattcgtat aaatatctcg gtccaaactg atgatcgttg
     6901 attttttttg tttcggatta actgttacta ccatcatcgt atcagaacgt ccttgttccg
     6961 ttcttcctaa tccaccggta tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat
     7021 caatgcttac tctctcagaa cgtttggagg atattcgatt agagttttta gaaattttgt
     7081 ttactgtttg gctcgcttct cccataaatc tgattccgta tgctgataat ccggcaatca
     7141 gcaaaacgaa tacccctaac aaggttaata gaactttttg ccatcgcttc ataatacacc
     7201 tctgtttcac attttctaaa atattgtctc atataactgt tcaatcagca aattcacttt
     7261 ttaatcataa gaaaacttta aaaaacattt ttgtgtaacg attattattt tttaaaattt
     7321 ctcaaaattc ttaactatca taccataccg tgaaaaagat cgaaagaccg aatacacgca
     7381 gttcgcaatc gttttatctt tttttatgta ttttttccag aaaaagcgaa caacaaggta
     7441 ttttccaaat aatcgtgcag taaaatgatc gcacatacct ttcccatctt tttaacagtc
     7501 tttgcctacc gttcagatta tcattcgatt tcacgacaat ttcttcctat gactggtcct
     7561 tttgttaaac ccatcttcta ttcgttttat ttccagctca ctgcatggct cttaaaatga
     7621 ctcgaactag tgattgcatt accatcatct tttaatggat agatatgctc ctcttcaaag
     7681 taaaacgatt ttcttttaaa gtaatagaat tgacatggta atgagtatgt atactagtgg
     7741 tttcacaaat ggtcttttat tcaacatcca aaaactgaaa tttctttaaa atccattact
     7801 aacgaagaaa atgttccttg cttgataatt agttaggaca tgtcaagtga acaaatgcat
     7861 ttacttagcc aaaaaatcta aaaacttcat aaatagacaa aaagacacga ctctctaaga
     7921 agtcgtgtct ttattcaaca aattattata atttagtcac ttcagcagct tgaggtccgc
     7981 gtgcaccttc aacaatcgtg aattctactt cttgaccttc ttctaggctc ttgaagccgt
     8041 ctccttgaat tgctgagaaa tgaacaaata cgtcatctcc gccgtctact gtaataaacc
     8101 caaatccttt ttcattgttg aaccatttaa ccgttccgtg ttccataaat gtatatcctc
     8161 caaaaaagtt cttgcaagta accttgcaag aacattatac ccaatttaga aaacgctagc
     8221 aagctttcgc tcttttattt tccaaattat ttttaagact gatatgacgg aggaaatggt
     8281 tattttgctg cttcgaaacg tttgtttact tcatcccaat taataacatt ccagaatgct
     8341 gcaatataat ctggtcggac atttttatat ttcaaataat aagcatgttc ccaaacgtcc
     8401 aaacctagaa ttggtgtctt tccttccatc aatggagaat cttgatttgc agtagaggta
     8461 atagctaatt ttccattttc cattacaagc caagcccatc cagaaccaaa tcgtccagcg
     8521 gctgcttttt tgaattcttc tttaaaagaa gaaaaatcac caaaagcttc attaatcgct
     8581 tcttttattt ctcctgtagg ttcgccacca gcatttggtg ccatgatttc ccagaaaaat
     8641 gaatggttag catgtccgcc accattgtta cgtacagctg tcttgatatc tgttggaata
     8701 gcgtccatat cagataataa ttcttctatt gttttttcgc ctaattctgg gtatttctca
     8761 attgctgaat ttaaattcgt cacataagta ttgtgatgct tatcatgatg cagatgcatc
     8821 gtttcttcgt caatataagg ttccaatgcg tcatatgcat aaggtagatc tggtaatgtg
     8881 taagtcataa aaaaattcct cctcaatgtt ttcttaataa tgtctacatt acaaagagta
     8941 acaaagagaa ggaaattctt caattgttat gcctagtcgt ctttttcact ttgacctact
     9001 tcttcttcaa aaacctcagt ttctttaaaa ataaacaact tgctgaaaat atagttcgca
     9061 aggataacaa taatttgagt gatgattttc gccacatact cattgctgtt cataacattg
     9121 atcaacaata ccattgcccc catgtccaat ccgtaagaaa ggatacggta gaagaagaac
     9181 ttaccgcatt caataagtgc atgtgtaaaa ttcggtgatt ttgaatggaa tacccaaagt
     9241 ttgttcgtta caaaagcaaa caatacagaa caaaaccacg aaatagaatt ggataaggcc
     9301 atacttaaat caaaatattg gcgtgcgaga gcaaaactaa caaaatttac aatcgtagcc
     9361 aaaccaccaa aaaagagata gactagtatc tcccaatatc cttttgcttc taaatatcct
     9421 tttaactgtc gatactgctt catgagccaa cctaccttat taaaaattct tatttatcat
     9481 actctatatt tcaataactt tcatctttat ttaaaaaaat taattttttt tgatcctttg
     9541 cctttgtctc tgcttggatc gtcacatgtg taataccata ttttaatttt aataaagaaa
     9601 ttatacgagg atatatcttt tcaatctcgc ttagtagctg atcttcaaaa tcaatatgtc
     9661 cgtcgaaaat aattatcttt tcgctatact gccaaatatg gacatgatga acatccttta
     9721 ccccatcgat tgcttcaatt tcttgttcca ttttttcata gtcgatagca ggtgcacttt
     9781 gtatcaaaat agcggcagct tttttgatca ccattatcgc ttctatcaat atatatatcg
     9841 aaatgatcag tgtaataact ggatcgatcc agtagatatc gaaaaaacgg atcaaaattg
     9901 ctccgataat cacacttacc gaagacagtg tatcacttaa caaatgcaaa taactagatt
     9961 ttatattcaa actttcatct gcttcttgtc gtaataataa tactgagaac aaattcgcga
    10021 gcaatccaat aactgctact gttagcatca aatgactatt tatcttttct ggtgaagtga
    10081 accgcttgaa tgcttcaacg gttaaaaaca aggataatat gatcaatatg aatgagttga
    10141 tgaaagcact caatatttct aaacgctggt agccatacgt acgtttttta tttgcttctt
    10201 ttcgggccat tttttgtgcc ccgtaagaaa aaataattgc caatgtatca ctaaggttat
    10261 ggaaagcatc tgaaacaaga gacaaactcc ctgacataat ccctccaata aattctgata
    10321 aagtgatcac cgcattcaaa accactactc caaatagttt ttttgatgat ctctgtggct
    10381 gtgtaggcac tattccttcc tccattttat ttatattgga tagtctttag acaagaataa
    10441 catttttttg atatttcacc aatcattcag ctgtttcctt aaagcacttg tatttcactt
    10501 gatacttcgc tagaattgca agtgatgaca ctactagatg aggagtactt atgacaacaa
    10561 aacaattaat tatcagttcc tttatacgat tcaaagacct aaaggaggcg agaaatgtcc
    10621 cattttggaa agccattgtc tatcttttag ttttgagtat aattatggct ttgccaatct
    10681 cttttcaagt ttttcaagtc ttaaacaaca ttcaattgga tgggcaaaag attgctactc
    10741 gcattcctga ttttacaatc caaaacgggc agcttcaaac cgaagaaaaa gaaggattca
    10801 tttaccaaac aaactccatt atcttcacat ttgatccaga gggaaaacga acagaacagg
    10861 acatctctac tgatttgatg gggaattttg ttagtgtcgg gatgttaaaa aacaaactta
    10921 tcatagctct tcctaataca ggcacgactt ctgctttgtt gaacaataac caattagaac
    10981 ttccctacac caatgaatct ttaaaaaact taacaggtaa gcagctccgt tcttttttaa
    11041 gtgaagcatc tataccactt tggataaaag tcctgacatt tatattttct atttatccta
    11101 gttttctgaa tctgctgatc actttgctat ttaccaacat tgctgctttt ctctatgcac
    11161 gctttcgact aacaaaagct acttttcttg attgtttaaa aacattgatc tattcaattt
    11221 cattgcctac tataattgca acaatcttga tggtctttct tccttctttt gacactagcg
    11281 ccttcattgc ttttgcagga atctttattt ttgctcaagc tgtcaaagga tgggcaaaaa
    11341 tatcgatcaa ttaagaaata aagacaactc gttatttcta cttcaataga cccttttaga
    11401 ggttgtgaca tttttttgtc acagcccctt ttttatttga aaaatatttc tttctcaaaa
    11461 aacaagcaag gcgcttcaaa gttcttcttg tatgcgctac acttagagta aagaaaggcg
    11521 ggaaattaac tatgtcagaa agaatcattt atgcagatcg tccatttcgt gatgaattta
    11581 tcgaagaaat ccatactata gcgcctggtt atatctttaa aacagaatta caaccagagg
    11641 atctacaaaa tgtagagatc agtttgggct ggaactcaga ctaccaagaa aaactattag
    11701 cctcttctac cttgaaatgg gtccaatcta tctcagctgg tgttgatcag ctaccccttg
    11761 agactttttc aaagaaacat attttacttt caaatggtag tggcatccac agtgaatcga
    11821 ttacggagca tgtcttagga atcatccttg ggtattctcg tggtcttttt caagcacaaa
    11881 aggcacagag tgacatgaaa tggttaggtt catcggtcca ttaccaatct atccaaggga
    11941 aaaaaatact aatcattgga actggccata ttggaaaaat gattgcaaaa aaatgcaaag
    12001 cattagacat gaactgctat ggaatcaata catccggtca tccagcagaa ggaatggaaa
    12061 agactttttc tttaaatcaa ctaaaggaag ttcttcctga agtagatttc gtagtcaata
    12121 tcttacctct aacggaggaa acaactgggc tctttgatca gcatatgttt gaacactttg
    12181 atccaaaatc tgtattcatc aatgttggcc gtggtgcttc tgttaagaca caagatctgg
    12241 tgcaggcttt aaataaccag caactttcct ttgcagcatt agacgttttt gaggaagagc
    12301 ctcttccaca agatcatcct ctttggaaaa tggacaatgt actgattact tcccacattg
    12361 caggtttgac acctgatttt caaaagaaat taatggctat ttttttaacc aatctgaaaa
    12421 gctactttgc cacccatgag cttcaaacca atcaagtaaa attgtctgca ggatattaat
    12481 agctgaaaac aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct
    12541 ctttttttat tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac
    12601 aagtaaatca tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc
    12661 atccatttcc actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa
    12721 accatcatga acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc
    12781 tggcagatca atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat
    12841 cccaacaacc tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac
    12901 atcgcctgtc tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc
    12961 aggagaagcg ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg
    13021 ttgcctgaaa tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat
    13081 ttctgctaaa gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa
    13141 attatgcgca atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat
    13201 cttttcaagt actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc
    13261 catttccttt accatcagag taactaagat actggcttga atatcttctc caatagcgac
    13321 aattacatga tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt
    13381 tgccacaaca gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc
    13441 aatagccagt acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg
    13501 tccaagacct acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt
    13561 ctcagtataa caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa
    13621 gaaaaataat agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca
    13681 ccaaaccatg tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag
    13741 ccaatatatt ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta
    13801 tttcctgatt actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta
    13861 gttcttcatg taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca
    13921 cttctggttc taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat
    13981 gtgcggtaga ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt
    14041 tttcgtcatc aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga
    14101 ttgcttttgt tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt
    14161 ccggtcgaag tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta
    14221 cttcaatgtc ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt
    14281 catctactaa taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga
    14341 tttctacact tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag
    14401 ctactcgttc tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa
    14461 accctgttcc gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata
    14521 cctctaattc attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc
    14581 ggaacaagtg atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg
    14641 aaatctggat tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt
    14701 tctcttctaa attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag
    14761 cgttgatgat ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt
    14821 tttctgcttg ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa
    14881 ctgaatcatg cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg
    14941 tttgtccatc tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa
    15001 tcattttttc ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg
    15061 atgcacttgg gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac
    15121 gcagcttttc ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga
    15181 caattaatcc tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata
    15241 aacgtgcacg cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga
    15301 aaagtgaaaa tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc
    15361 tggatatttt tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat
    15421 aatcttcaat ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt
    15481 tttcaaagaa aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa
    15541 tcggatggct acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat
    15601 cacaatatta tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga
    15661 aatgacggcg atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc
    15721 gaataattgc tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat
    15781 catgatctgt ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac
    15841 acctttcaga ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt
    15901 gactaagcta aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt
    15961 acgaggatgt ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa
    16021 aagtccagta ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac
    16081 cacaaaaaaa cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc
    16141 atcataccta tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa
    16201 atctaaaata cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta
    16261 gatctttcag tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc
    16321 tggagtagca atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg
    16381 agaatcattg gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta
    16441 ctcttcttct tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc
    16501 atctgcatct acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt
    16561 tgtgattctt ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc
    16621 ggaaagatct ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac
    16681 tgtttttagt tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata
    16741 aactttctct accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct
    16801 tttgaggaat atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct
    16861 aaaaatgatc aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa
    16921 ttccatatgt tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac
    16981 gaaataataa tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg
    17041 attgtcaaaa ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac
    17101 agctgtatct tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat
    17161 atctgactga agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt
    17221 acgatcattt tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg
    17281 tacagtcaaa tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt
    17341 gttcaccatt tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc
    17401 tgggaataag taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa
    17461 cagttctggg aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa
    17521 aaattctttc ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc
    17581 gtacccttct ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc
    17641 ttcttgcaac tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc
    17701 agcttgaaag ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt
    17761 aataatattg tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat
    17821 ctcgacttgg actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata
    17881 acgatacacg gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa
    17941 aatgatcttc ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat
    18001 atctgctgta gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc
    18061 tgacaaaaca actcctcctt actatcaagt tcgtaacttt attcattata catgatattt
    18121 gaattggcgt gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt
    18181 actataagat taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt
    18241 aaaaaagaaa ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa
    18301 aatattcatt tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa
    18361 ctattcttgg atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat
    18421 cagctcaaaa aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc
    18481 aactattaag aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca
    18541 tcatggaaaa aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc
    18601 tttattatca gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag
    18661 tcgagcgtgg gcacctttct ttagatacta agctggctca attctatcca caaattgctg
    18721 gcagccagca aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg
    18781 cttctccaac cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa
    18841 aatttacaga ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa
    18901 ttttgatcaa attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac
    18961 ctttaggatt acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac
    19021 tatcctatca aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag
    19081 agatccataa cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc
    19141 tgtttacaca agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc
    19201 gtgaaaatgc gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc
    19261 tgtcgcaagg aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg
    19321 atgctatcat catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg
    19381 atctaagaaa ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat
    19441 atgatgaaaa gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg
    19501 actaaacgta ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa
    19561 ttccaaataa acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa
    19621 gatttctctt taccaacatt atttgacaaa gggccta
//
LOCUS       DACGDM010000042        18740 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.043, whole genome shotgun sequence.
ACCESSION   DACGDM010000042 DACGDM010000000
VERSION     DACGDM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.043"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            256..531
                     /locus_tag="IXR05_001630"
     CDS             256..531
                     /locus_tag="IXR05_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260134.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            544..2616
                     /locus_tag="IXR05_001631"
     CDS             544..2616
                     /locus_tag="IXR05_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4260135.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            2781..4667
                     /locus_tag="IXR05_001632"
     CDS             2781..4667
                     /locus_tag="IXR05_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4260136.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4679..5626
                     /locus_tag="IXR05_001633"
     CDS             4679..5626
                     /locus_tag="IXR05_001633"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4260137.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5646..6173
                     /locus_tag="IXR05_001634"
     CDS             5646..6173
                     /locus_tag="IXR05_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4260138.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6236..6889)
                     /locus_tag="IXR05_001635"
     CDS             complement(6236..6889)
                     /locus_tag="IXR05_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4260139.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7021..7863
                     /locus_tag="IXR05_001636"
     CDS             7021..7863
                     /locus_tag="IXR05_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4260140.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8021..8917
                     /locus_tag="IXR05_001637"
     CDS             8021..8917
                     /locus_tag="IXR05_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4260141.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8920..9633
                     /locus_tag="IXR05_001638"
     CDS             8920..9633
                     /locus_tag="IXR05_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4260142.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9653..10171
                     /gene="msrA"
                     /locus_tag="IXR05_001639"
     CDS             9653..10171
                     /gene="msrA"
                     /locus_tag="IXR05_001639"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4260143.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10168..10395
                     /locus_tag="IXR05_001640"
     CDS             10168..10395
                     /locus_tag="IXR05_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4260144.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10547..11098
                     /gene="lepB"
                     /locus_tag="IXR05_001641"
     CDS             10547..11098
                     /gene="lepB"
                     /locus_tag="IXR05_001641"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4260145.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11181..11723)
                     /locus_tag="IXR05_001642"
     CDS             complement(11181..11723)
                     /locus_tag="IXR05_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4260146.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(11960..12358)
                     /locus_tag="IXR05_001643"
     CDS             complement(11960..12358)
                     /locus_tag="IXR05_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4260147.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12618..13478
                     /gene="ylqF"
                     /locus_tag="IXR05_001644"
     CDS             12618..13478
                     /gene="ylqF"
                     /locus_tag="IXR05_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAQ4260148.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13471..14238
                     /locus_tag="IXR05_001645"
     CDS             13471..14238
                     /locus_tag="IXR05_001645"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAQ4260149.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14294..15151
                     /gene="dprA"
                     /locus_tag="IXR05_001646"
     CDS             14294..15151
                     /gene="dprA"
                     /locus_tag="IXR05_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAQ4260150.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15273..17351
                     /gene="topA"
                     /locus_tag="IXR05_001647"
     CDS             15273..17351
                     /gene="topA"
                     /locus_tag="IXR05_001647"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAQ4260151.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17320..18696
                     /gene="trmFO"
                     /locus_tag="IXR05_001648"
     CDS             17320..18696
                     /gene="trmFO"
                     /locus_tag="IXR05_001648"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAQ4260152.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
BASE COUNT         6518 a         3231 c         3899 g         5092 t
ORIGIN      
        1 ttttgtcgca gccccatttt tttgttgtga taaaagaaca agaaaggcag gaatgggaaa
       61 gtaaacatcc ttttgtcaga aacttttatc tttcttaagt tttacttgat atctgatact
      121 atttggaata gaatgaggcg ttgaaaaatt tatggaaatt tctaactagc aataaacgat
      181 gaaacaatga aatatttttc atccaaaaag aactttgcta taatgatgga agtttgtgta
      241 taggagatct ggaaaatgag agagagtttt gaacaacaaa aaaaactgtt gcatgatcgc
      301 tatggcgccc tttcgatgga tgaccgccgt caaatacttt gtaagttgcg taaaagaaat
      361 atattgatgt atcgtcagtt ggaacgtctg aaacatgatc tgcttcgttt ggagtcaaaa
      421 cgtgtacagt gtgaattaga ggggaaccaa acacaggttg aagtagtcga aaccaaaatt
      481 ttaaagaaaa aagaacaatt tttaaaaatg cttacacaaa ataaaaaata aaggggatgg
      541 acgatggaat ttgctgagtt agttattgta tttgcagtaa cgatcacctt atcgaacata
      601 gctagccgca ttttgccaat gattccagct ccactgatcc aaattttcct tggagtggta
      661 ttaggtctga cagagtgggg acaatcaatc gattttgaac ctgaattgtt cttagttatg
      721 attattgcac cattgttatt tagagaagga gaaaaagcag atatttcttc gattctcaaa
      781 aatttcggga caattttgtt cttggcattt ggaggagtca ttttgaccct tgtcggggta
      841 ggtgcgacgt tatcattcct gttgccaagt gtcccacttg ctgcctgctt tgcttttgga
      901 gcagcgttag gtccgacaga tgcggtagca gtcagttctc tttctggacg agtgaatatc
      961 cctaaaaagg cgatgcatat tttggaagga gaaggtcttt tgaatgatgc atctggtgtt
     1021 actgccttcc agtttgctct tggtgcgctg atcaccggat ctttttcagc agtaaacgcg
     1081 gggatgagtc tagtagtttc tagtattggg ggagctttga tcggcttttt gcttgtctgg
     1141 ttcaaacaaa aaataattca tttgatcgaa aaagcatcag cacaagatgt cacagggtat
     1201 ctgctgatcg aacttttgct tccttttcta gcctatgtat tggcagaggc atttgatgta
     1261 tctggaatca ttgctgcagt ggcagcaggt attctccaag cttctggttt taggaaaatc
     1321 tctgtgtttg atgcagaatt gtcgagcttg tcccacagta catggacaac tattgctttt
     1381 acactgaatg cattagtatt tatattttta ggaatcgaat tgacgcaagt gttctcgcca
     1441 gtatggggag acggtttata tccaaacggt cttttattag cgattatcgt attaatctct
     1501 gtcatgcttt ttgtgatcag attcatttct atcagtcttt tttatgtatt caaagatggc
     1561 agtaaaaagt tcaaaaaaca gttgaacgag atcttgatct taacatttgg cggtgtaaag
     1621 ggaacagtca gtttggctac gatttttatt ttgccatttt caatcaataa tatgatgttt
     1681 taccagcggt ctttgctttt gtttctgacg gcgggtgtca tcttagtgac tttggtcata
     1741 gggatcattg tcttgcctat gctgacggaa acagaggaag cgaaaagcac ggatttgaat
     1801 gctttgatga ttttagaaga ggtcgttgaa gttttgcgaa aagaaataaa ggaaattgat
     1861 cgtaatacaa aagaattttt agccactgaa gcagtgatag aaaattatca agaacggata
     1921 cgtgatctgt acttggaaga tttaaccgat gatgaaaagc aagaagtaca agaaatacaa
     1981 gcactgattt tgtcgatcga acgggatgga ttggatgaaa gttatcgttc gggcaagctt
     2041 tcttctaatg gttatcgttt ttactcccgt tttctttctc gattcgaaca ttctatcaca
     2101 agccagattt tgtcttttat cggcttttgg ttcattgttg tccgtaggtt aatgcgaatc
     2161 gttctccatc cgaaaatgtt ttggcaaaga agatatgctg atcgtcagac atttattagt
     2221 gatgaagata tccaagaaat cagagagaca tatcaaaaaa atactcagtt gattattgaa
     2281 agtttagata acttgactga tatttatgat gaaacgatgg ttcaattttt tatccagcaa
     2341 cgcaaacttg aaggaataaa aatgaactcg gggaatttga tttcttcgtg gatgatccag
     2401 caagatagtc tgtttacgaa aaaaatgcta agaggttatt atcttgaaag aaaaatcatt
     2461 gatgaatacg aagttgctga aaaaatcacg acgttttctg cgaacagcta tcgcaggaat
     2521 atcaatttgt tagaatctta tacgatgaac aaaccatctg ataacttttc tttccgattt
     2581 gcgtttcgag caaagtcaaa aaaacgagtc caataaaata aaaaggtaaa aattttcaag
     2641 ttttataaaa aacaaaacat atcagaacag gatcgaatcg gtcctgttct ttttttgaga
     2701 acacaaaaag aacaaatacc aaaaaaattt tcctgaagtt cactattttt atgatacaat
     2761 atccaagata aggagggaac atgttgaaag aattaaaagt aactgacctc aaaaaaactt
     2821 atggtgaaaa agatttgttt gaccagattt cttttttggt ccacgaaaaa gaccgtatcg
     2881 ggttgattgg gacgaacggg acgggtaaaa caagtctctt aaatattatt gccggtatcg
     2941 atagcagcga cggtgatcgg caaacagtgt tttatccaac tgattaccgt attggttatc
     3001 tttctcaagc agctgaattt tccgatgaat taactgttct ccaagcagtc tttcaaggaa
     3061 acagcccctt gatccaaact gttcgagcat atgaggaagc attgatcgaa ctaggggaaa
     3121 acggagaaga ccctgatgtg caaaaacgtt atgctaaagc agaagaacaa atgaataaag
     3181 aagatgcttg gactacagat accaacgcaa agattatttt gcaaaaatta ggaatcagtg
     3241 aattagataa aaaaatcagt actttatcag gtggtcagaa aaaacgagtt agtctggcgc
     3301 aagtgttgat tgatgaaccc gatttactat tactagacga accaacaaac catttagatt
     3361 atgaagcgat cgagtggttg gaaaactatt tgaaacaata ccgtggcgca ctattgatgg
     3421 ttacccacga tcgttatttt ctagatagag tagcaaaccg aatcttcgaa ctttcatttg
     3481 gaaaattata cgagtataaa ggaaattatg aagcttacgt cttagaaaaa gcagaacgtg
     3541 atcgtgtaga agtagaacaa gaagaaaagc gcaagcggct ttataaacag gaattagctt
     3601 ggatgagggc tggcgtacag gcacgtggca ccaagcagca agcacggatc aaccgtttcg
     3661 aagatctaaa ggagaacttg taccaagtaa accaagaaga tgatttagag ctgaacctag
     3721 cgacacaacg tttagggaaa aaagtactgg aaatcaaaga tggcagttac cgtataaatg
     3781 accaaacact gctagaacat ttagatttat tgattcaatc tcgggaaaga ctaggtatta
     3841 ctggtaaaaa tggtgcggga aaatcgacat tgcttaatat tctagctggc agaattcccc
     3901 tggatagcgg tacaatgtct atcggtgaaa cggttcatct tgcgtattat acacaagaaa
     3961 atgaagaaat ggcaccagat aaacggatga ttgcttactt acaagaagct gctgaagaag
     4021 caaaaacagc agatggcagt caaatcggag tagcagaatt acttgaacga tttttatttc
     4081 caagatttat gcatgggaca ctgataggca aactttcagg cggagaaaaa cgccggttat
     4141 ttttgttgaa actgctgatt cagcaaccta atgttttatt attggatgaa ccgaccaatg
     4201 atttggacat agcaacattg acgattttgg aagattattt tagaagtttt ccaggtgctg
     4261 tgatcactgt ttcccatgac cgttatttct tggacaaggt agcagataag ttattagtat
     4321 tccaaggaaa cggaaaacaa gaactttatt acggaaacat gtccagttat ttactgaagc
     4381 aaaaagagac ccagcagcct gctgaaaaag cgaaaccaaa aatacagagc aaggaacctg
     4441 ctgaaaagaa gaaattatct tacatggaac aaaaagaatg ggaaacgatt gaagatgaga
     4501 ttgcagaact tgaagaaaaa atctcattgc tccaagaaga gatgaatcat caaggagata
     4561 atttcactcg attacaagaa ttgcaaaacg acgtatctga aacagaagca caacttgaag
     4621 aaaaaatggc acggtgggaa tacttgagtg aatgggtaga agattaggag gaaaaaggat
     4681 ggaacaagcg tatcttgact taggaagaaa attgttggaa gaagggcatc gtaaagaaga
     4741 cagaacaggc acaggcacat taagcttatt cggataccaa atgcggtttg atctgcaaaa
     4801 agggtttcct ttgttaacaa cgaaacgagt accttttgga ttgatcaaaa gcgaattgct
     4861 ttggttttta aaaggagata cgaatatccg ctatctatta caaaataaaa accatatttg
     4921 ggatgaatgg gcatttgaac gctacatcaa aagtccagac tataatggac cagatatgac
     4981 tgattttggc catagatgtt tgacagatcc tgaattcaat gaagaatata aaaagcagag
     5041 caagcttttt tgcgagaaga tcctaaccga tgattccttt gctgaaacat acggcgatct
     5101 tggacacatc tacggctatc aatggcgtca ctgggaaaca aaagacggtg gctttatcga
     5161 tcaaatcaaa caagtgatcg aagcaatcaa aaagactcct gattctagaa gattgatcgt
     5221 ttctgcatgg aatccggaag atgttcctag catggctttg cctccttgtc atacgatgtt
     5281 tcaattttat gttcaagagg gacggctaag ctgccaattg tatcaacgca gtggggatgt
     5341 gtttctaggc gttccgttca acattgcaag ttatgcgttg ctgactcacc taattgcaca
     5401 tgaaacaggt ttagcggttg gcgaatttgt tcacacatta ggagatgctc atctttatat
     5461 caatcatatc gaacaaatga aagaacaatt gagccgagaa atacgcgcat ttccgacttt
     5521 agttttgaat caggaaaagc agtcagtatt tgattttgag atggaagata tccaattaga
     5581 aggatatgac ccacatccgg cgatcaaagc tcctatcgct gtttagaatc agaaaggatg
     5641 agaaaatgtt agctgcaatt tgggcacagg atgaaaacgg attgattgga aaagaagacc
     5701 gtcttccttg gcgtttgcca aatgatctga aattcttcaa acaaatgaca gaagcaaata
     5761 cactagtgat gggacgaaaa acattcgaag ggatgggtag ccgtccgttg ccgaatcgtc
     5821 agacgattgt tttgacgaga gattcttcct ataaagcaga aggcgtgcat gtcatgcata
     5881 gtgtggaaga cgtgcttgct ctggaaaaag aaacagacgg tatctttttc atcgctggag
     5941 ggtcagctgt ttatcaagaa tttctgccat tttgtacgat attataccgt acagtcatcc
     6001 atcatgtatt cgatggagat gcttattttc cacctgttga ctggtctgat tggtcactga
     6061 tcaatactag tcaaggagaa atggatgaaa aaaatcgtta tccgcatcaa tttgaaacgt
     6121 atcagcgtaa tgagaatcct gtaaaaagcg ggacaggcga attgacgata taaaaaagct
     6181 atggatagac tagctgttat ttagagctgt cccatccata gctttatttt ttttattaag
     6241 taaagaataa aacagagaag tacataaaac ctgcacctaa cataacaaac aaatgccaaa
     6301 caacatgcat atagcggata gaattcaagc tataaaagaa tgcgcctatc gtgtaagaaa
     6361 gcccgcctgc taccatcaaa ataacaccag tcattccaag agagtgataa agaggaacag
     6421 cagccacgac acagagccac cccataaaaa tatagatgat cgtagatact tttgatactc
     6481 tctcccgttt atgcaacgtc aacgctttat atataatgcc aagaatcgca aacaaccaga
     6541 ttaatacaaa taaagtccaa cctagccatc ctcggatact cagcaaacaa aaaggagtat
     6601 aacttcctgc aatcaaaaga aaaatcgaac tatgatcgaa tacttggaac accttttttg
     6661 cttttgtaaa aatcaatgaa tgaaacaaag tagacgttaa aaataaaaga atcatcatcg
     6721 atccatagat agcataagag acaatatgga gggaggaatg caagtgggca ccttttacta
     6781 aaagaaccac tagtcccgcg atactcaatc cagtcccaat tccatgggtg actgcattaa
     6841 acacttcatt taatatttca tacgttcgat taaatttcgt tttttccatg aaaacggctc
     6901 ctttactagg tgtaattaat gaaaaatcat tatttgtctg ttatactaaa aatagaaatt
     6961 gtcttacatg tagtttaaca tgaataaggc atcttgttaa agaaagagag agagaaaata
     7021 atgacaaatg taaaaatcgt aacagattct tcatgtacga tggaaaaaaa tgtacgcgat
     7081 gctttaggca ttcgtgtcat gccgctatcc atcatgatcg acggaacagt atatcccgat
     7141 gatgaccaac tagacggcga aagatttatg gaaatgatgg cgaaagcaaa aaatctgccc
     7201 aaaacaagcc aaccaccaat tggagaattc atctcgatgt atgatgagct aggagaagac
     7261 ggcagtgaag tgatttcgat ccatatgaca aaaggcttga gtggaacagt agaagcagca
     7321 agacaagcca gtaatctaac aaaaacgaaa gtaacggtta tcgacagtga taccactgac
     7381 caaggattat cttttcaggt aattcgagca gctgaattag caaaagaagg taaaacagta
     7441 gagaaaatcc ttgaagaagt caaaaaagta caagacaata caaaattata catcggaata
     7501 tccacactag ataacttggt aaaaggtgga agaatcagcc gaacaactgg tttgctgtct
     7561 agtgttttga acatacgcgt ggtgatgaat ttcgcccatt ctgaattaat ccctgtaact
     7621 aaggggcgag gaaagaaaac gttcgataaa tggtttaata atttgaaaaa tgaactgaaa
     7681 gaattgccaa atgtgcgaca aatcggtatt tcacatgcgg atgcaaaaga attggcgcaa
     7741 gaattcaaag agggtttgca agaattattc ccggacatgc atatccctgt actgcatacg
     7801 aatccggtta tcgctacgca tactggtaaa gacgcgtttg caatcatgta ttatgtagat
     7861 tagtcgaaaa gaggataagc cctcagcctg aaaggcttgc agcttattct ctttttcttt
     7921 ataaaattag gaaaataatt gttttctttt ttcataaaga ctaccttttt gataaaattt
     7981 ttgataacat tagaaccaat cgaatacaag aggtgaaaaa atgaaattaa cgaaacgaca
     8041 tttgatcctc gttttgttcc cattattaat tgcgatcatc atctatgcag gtttagctgc
     8101 ttctataccg aaagctggcc cactaatgaa accagtaact actgtgagag aagatccaaa
     8161 taaaaaagaa aaacttcact acatagctat cggagattcg ctgactgaag gagtaggaga
     8221 tcaaaccaag caaggaggat tcgttcccct tgtcgcaaat gatctaaaag accgttataa
     8281 tttgaccgcg gttgaaacag aaaactatgg tgtaaatggt gaacgaagtg accagatctt
     8341 aaagcgagta aaaacaaaag aagaaattcg aaacaatatc aaaacagctg attttatcac
     8401 actgactgtt ggcggtaatg atttgatgaa agttatccaa aataatttat tcgggttaac
     8461 ggtcaattcc tttaaaaagc cactgaaaaa ctatcaggaa aatgtcacag aactattgga
     8521 agaatttcga tccctcaata aaaccgcacc tatttacatt ttaggcatct acaatccatt
     8581 ttatttgaac tttcctgaga tcactgacat gcagacaatt gttaacaatt ggaacaaagg
     8641 aacagaaacg gtgacaaaaa aaatgccgaa ctgctacttt atcccaatca atgatttgct
     8701 ttatcaagga ttgaatcagg aagtaggtgt cacagaagaa ggaacagatc aaacaactag
     8761 cacgacagaa aatctaaatg gcatcaaaaa taatgtgctc tatgaagaag atcatttcca
     8821 tccaaataat ttaggttatc aattgatggc aaatgcagtg agagatcagc tgatcgagac
     8881 acaaaaccaa tggttagaga aggaggatga tcaataaaca tgaaaacaag atctgacgta
     8941 tcttcaaaca aaacaaagaa aacaaattac tggaaattcg ccttccttat ccttcttggg
     9001 gtagtacttg gttcgaccgt atttttaggc agccgtattt ttgctaatcg ggaaccagaa
     9061 ctcccagaaa taccagctct tacggaaaga caaggagatc ctgtcttaac gatcaattca
     9121 aataaagaaa aagtcaatca aatcatcagc tttttcctta gtgagtatca aaaagatagt
     9181 gatattgaat ataaatttta tttggaaaat gaagcactac tcaatggtac tttcgaagta
     9241 ctaggttttc ctatcgattt ctatttatat tttgatccgt atgtgatgga aaacggaaat
     9301 gtccaactaa aagctagaag tctttctatc ggaacattga gtttgccaat caaagatgtg
     9361 atgaatatga tcaagagaaa ctataaatta ccagattgga tcgaagtcaa tacagatgat
     9421 ctgactatca tgcttaggtt ggatcaattc cgaatgcaaa acgggatgta tattaaagca
     9481 gataaaatcg acttagtaaa tgatgacatt cggtttagtc tatatttgcc aaaagatacc
     9541 tctgatgctt caaacaactc aaataccaac aaaactagca ccagcagtac tgaaagcaag
     9601 acaaaagaaa ataaaaaatc atcggatgag tagtattaga gggggaatca taatggaacg
     9661 agcaatattt gcaggaggct gcttctggtg tatgatccag cctttcgaca cgcttcctgg
     9721 tatccataca gtgatgtcag gatatactgg agggcatgta ccagatccga cttatgaaca
     9781 agtaaaaagc caaacgactg gacatacaga agcagtggag attatctatg atccaacatt
     9841 gatttcatat gaacaattag tagaacttta ctggcagcaa actgatccaa ctgacgcttt
     9901 cggacaattc gaggatcgcg gtgacaatta tcgcccggtg atcttttatt tgacagaaga
     9961 acagcggatc attgctgaaa aaagtaagaa acagttagct gaaagtggac gtttcgaaca
    10021 gccaatcgtt acaaaaatcg aaccagccca accattttat ctagcagaag aagaccatca
    10081 agagtattat aaaaagcatc ctgaaaattt taaaagaaac catgcacgcc gggctgcctt
    10141 tatcgaagaa aattggagga acgaagggtg aatcgaagct tttttcatta tttaatgaca
    10201 ctgcgaggcg gtggcacaca tgatgcttta tctgttttcg ctacagaagc cggtaaagac
    10261 atccaatttc ctaagcacag ctctagctac gaagaaattt ctaattatct ggaactgaat
    10321 gtcgactatt tgccgtccat ggatatcttt gacgaagcat gggaaaaata tttagaaaat
    10381 aatcatgaca tataagagat agttttgtac tttatgatca aaaaagtttt ttgtccaata
    10441 gcctaattga aagaattatt tttatttcag ctatctagtc gcattttttt gatatttttc
    10501 ttataataaa gaaagaatga aaaaaagagg gatggattga tagagattga caaaaaaaca
    10561 acgctatatt aatcgcttct ggcttgtatt caaatactta cttgtttctg tattccttgc
    10621 gttcatgttg cggggatttt tattcatccc ggtaccagtg gaaggcaatt caatggaaaa
    10681 cgtgttgaag caaggtgata tggttgtgat ggaaaaattt tcggagatca gacgatttga
    10741 tattgttgtt tttcaattag cagatggcac gatttatatc aaacgagtaa tcggtcttcc
    10801 aggagaaaat gtcagctacc aaaatgatca attgaagatc aatgggaaag tagttaagga
    10861 accttatcta actaaaaacc tgaaatcaga tcatgcaaat gcatcctata cgacggactt
    10921 tacactacaa gagctaacgg gacaatccaa gcttccggaa gataattatt ttgtacttgg
    10981 agataatcga agagtttcaa aagatagtcg ttcgtttggc acgatcaata aaactgatat
    11041 tctaggtaaa gcaagatttg tctattatcc acttgatgaa ataaaatgga tccagtgaga
    11101 aacaataaag cgtgcagtct gttgagactg cacgctttat tgtttaatcc aaaatcagtt
    11161 tactacctta gtacgtaaaa tcaaacagct cgtttaaaca cttttctagc ctctaaagtt
    11221 ttgataaatg aataaacaac cattatttga atagggattt ggatcatatt cctgatgaat
    11281 ctacctagaa aaattacttt gaaatctgca ccaaacaaaa cagacatcag ccaagaattg
    11341 ataaaaaggc tgactgggat cataatcaat aattgggcag cgatgacgga aggcaggttt
    11401 atctttttat gatataaaaa taagccatta ataaatccac caaggaaagc cgtgataaga
    11461 aaagcagctt gaaacgttcc tgaaccaaat atcgtgaaat ttaaagtgtt cgacaacatt
    11521 tcaagcaaac cagcccagat cggtccatat agataaccca taagcgccat acttaaaaat
    11581 ccgaatgtga tttgaaaata agcaggacca atcgctatct tgtataagat gacatcaagg
    11641 gctaataaaa gagcagaggt cgacaacaat cttgcattca tttcgggcaa tctaaaaacg
    11701 tcttttgcaa tcaaagtgtt caaaatattc tctcctttgt cagttaataa taaaaggata
    11761 ccataaaatc accaatgtgt catgacacat tggtgattta catacactgg catctaacaa
    11821 ttaaaaaaag ggtgagaaga ctgcttttat aaactgtaaa aaagagattg tacgaataaa
    11881 aaaaatagag gcggagaata cttatcgtat catccgcctt tgtttttttg ttataaaaaa
    11941 cgtcagatta gttatctgct tacatcttca tccatacggg ttctaatgta tttccgtcta
    12001 gatcttggac ttctaatgaa aacatttctt cttcaggcat tcccatatct acttcgtgga
    12061 aagtaccacc attttctttt gcaatttgag caaatttttt tacttcatcc gcgttttcaa
    12121 cactaaacga aatcaaagca ccacttgttt ttttattatc agctatttct ttatctttta
    12181 taaatttttt ataaaaatca tgagagagaa gcattatcca aaaagtgtca tcccatacca
    12241 ttgaaccagc ttcttcagta gaaaattctt catttttttt aaaacccagc ttttcataaa
    12301 aagcaacgga acgattgaca tcagcaacag gaaaattaac aaaaaccata ctattcattt
    12361 gtttcgtctc ctttctgttt tgttcgtcta tcatctctta tttaggaaac gctgtcaaaa
    12421 atttagattc atatatagaa accaaaataa aaatttgcat catcaaaaaa gtgaagatgt
    12481 gatagaatga ggactggttc actttcactt aactaataga tggaatttct ttataataaa
    12541 aaagtgaatt tatattgaaa aagaaaaaaa caagtaaagc cggggaatat tccggtatga
    12601 aaggaatgga gagaacaatg accatccaat ggtttccggg acatatggca aaagcccgac
    12661 gagaagtttc tgaaaaaatg aaatatgtgg acatcgtatt tgaattggta gacgcacgat
    12721 tacctttatc ttctcgtaat ccaatgctag atcagatcat tcagcaaaaa cctcgccttg
    12781 ttttattgaa taaagcggat ctggcagatc cacaacagac aaagctgtgg caagaatatt
    12841 ttcgtaaaca aggccatctt gcattagcta tcacggcaca agaaagtaaa ggaattaaag
    12901 gtctagtacc tgcggctaaa gaagcattga aagaaaaacg ggcaagagat gctgctcggg
    12961 ggatcaagcc tcgcgctatt cgggcaatgg tcttaggtat tccaaatgtt gggaaatcta
    13021 cgttgatgaa tcgactagta ggcaagaaaa ttgcacagac aggaaataag cctggcgtaa
    13081 caaaaggtca gcagtggctt cgtttaggta atgagttgga attgttagac acaccaggga
    13141 ttttatggcc caaatttgaa gatgaagaaa tcggcaaaaa actagcgctg acaggcgcga
    13201 tcaaagacca gcttgtccat ttagatgatt tagcgattta cggattagac ttttttgccc
    13261 gatattattc aggaagaatc agcgatcgtt atggtttatc aatcgagcaa gaagaaaaat
    13321 tggcaccgga attactgatg gatattacag caaaacgtgg gtataaagaa gactatgatc
    13381 gtggcagcga attagtcgtg catgatattc gtcaaggaaa acttggacga tacacactgg
    13441 atcgttgcga agaaatggag caaaaaagtg atgactgaat ccatccaaag tatcaaagaa
    13501 cgattgaaaa gcatacagag aatagatgat cctacactag aatcattaag aaatgatcca
    13561 cgcaaaggcg tgcagcaagc actggcttct tttgaacgac gattgaaaaa ggaagcatta
    13621 attaaggaaa aatatgaaga aatgttttgc tttgaaaagc aagggtacgc acaaggtcac
    13681 caatggattg ccggcattga tgaagtagga agaggaccat tagctggacc tgtcgtggca
    13741 gctgcagtta tcttgccgaa aaatgagatc atattagggc tgaatgactc caaacaatta
    13801 tcagagaaaa agcgagaact tctttatcaa caagttcaag aaaaagccct ggcaatcggg
    13861 atcgggatcg ttgatcagca gacaatcgat gatgtgaata tttatgaagc aagtaaatta
    13921 gcgatgatcc aagcagtaga aaaattgtcc attgtaccaa gctatttgtt gatcgatgcg
    13981 atgaccttgg atttgcctat tcagcaggaa aaaataatca aaggggatgc acgatctgtg
    14041 tcgattgctg ctgcaagtat cattgctaaa gtatatcgag accaattgat gaaagaatat
    14101 gacgtgcttt atcctggata tggtttctcg cataatgcag gttatggaac aaaggaacac
    14161 ttagaaggac ttgaacgaca aggaattacg ccaatccatc gtaaaagttt tgcacctgta
    14221 aaaaaatatt tacaataaaa aacagccgct tttacgtatc ttattagaaa gagagacgaa
    14281 aggcggtttt atgatgtatc aaatagaaga aaatttattg aaacttgctt atacaaaagg
    14341 aatcagtagt caaggaaaat gggcacttgc taactggatg atgcagtatc cttataaaga
    14401 aatcggattt gaagacatca ttaagatagg taaaataacc aaacatcggg agctgtttcg
    14461 caaaagttgg caggaaattc acgctaactg gggcaaaatc caatcgaaac agtcgtttat
    14521 cacttgcttt gatcccaaat atccccctca gctgcttcac ttgacctatc cgccaattgt
    14581 actgttttat aatggtgatc tatctttact ttcttgtaac atgttaagcg ttgttggtgg
    14641 aagacacact tctgctttag ccaaaaaaac agtttattat ttactaaaac cagtgataga
    14701 agctggatat gtgatcgtca gtggctgcgc gaaagggata gatacatacg gtcaccaagc
    14761 agcaatctct catggtggac ggacaatcgc agtcattgga acagggatag agcaagtcta
    14821 tcctgctgaa aatcgtgact tgcaagaggt gattgcaaat gatcatcttc ttttgagtga
    14881 atatcctcct caatccggcc cgaaaaagca ttgttttcca atgagaaatc ggattatcgc
    14941 agctttgtct aaaggaacat gtgtctttga agccaagaaa aaaagcggct ctctgataac
    15001 agcacagcaa gcattggatc ttggaagaac agttttttct gttccaggaa atattttaac
    15061 agaacattct accggatgtc atcatttgat ccaagacggt gcagtttgca cggtttcggg
    15121 tgaagatatc ttggcagaat ttaaagaata acaccatact tttcatttgc ttttcttgac
    15181 aaacgttttc tgaatggata tgattagcta cgatttgtat gaatcctctt ttaatagtag
    15241 gaacacgaca atggaaagga gtccattcag taatggcgta taaatattta gtgattgtag
    15301 aatcacctgc aaaagccaag acaattgaga aatatcttgg acgaaactat aaagtaatgg
    15361 ccagtgttgg ccatataaga gatttaccga aaagtaaaat gggtatcgat tttgaaaaca
    15421 attatgaacc ccattatatt tctatacgcg gaaaaggcga tgtcatcaaa agcctgaaag
    15481 ccgcagcaaa aaaagctcaa aaagtttact tggcaagtga cccggataga gaaggagaag
    15541 cgattgcttg gcatttagcg tacctacttg ggttggatct gaaagaaaaa aatcgggtgg
    15601 tcttcaatga aatcacaaaa gacgcagtca aagcagcttt taaggaacca agaacgatcg
    15661 atgtagattt agtagatgca cagcaagctc gtcgtacctt agacagaatc gttggttatt
    15721 cgatcagtcc tattctctgg cgtaaggtca agaaagggtt aagtgcagga cgtgtccaat
    15781 ctgtcgcttt aaaaattatt attgaccgtg aaaaagagat ccgagaattt gttccagaag
    15841 aatattggag catcgacggt aattttaaaa aagctcgcaa gaaattcaaa gcaaatttct
    15901 ggggaatcga cggtaagaaa aagaaattac cagatgcaca aagtgtaaaa gaagtcactg
    15961 ctagaattga tggaacagac ttcgaagtta aaaaagtaga aaagaaagag cgcaaaagaa
    16021 accctgcgaa tcctttcact acaagtagcc tgcaacaaga agctgcccgt aagttaaact
    16081 ttcgaacaag aaaaaccatg atggtagcac agcaattata tgaaggaatc actttgggta
    16141 aacaaggaac agtcggcttg attacataca tgcgtactga ttctacccgg attgccgata
    16201 cagcaaaagc agaggccgca gcatttattg aagatacgta tggaaaagaa ttttctagac
    16261 atgatcaccg aaagatcaaa aatgctcaag gcgcacaaga tgcccatgaa gctgtgcgtc
    16321 caacgagtgt gcttcgtaca ccagatgaac tcaaacaata tttagataaa gatcaattga
    16381 aactttatac attgatctgg tcacgttttg tggctagtca gatgacacca gctattttag
    16441 atacaatgaa agtgacatta gaacaaaatg gtgtcatctt cattgcgaac ggttcaaaaa
    16501 tcaaattcaa aggattcatg caagtgtatg tggaaggtag agatgacggc aaagaagaga
    16561 aagaaaatat tcttccagaa cttgaagaag gcgatgtagt ccaatctgtt gatattgaac
    16621 caaaacaaca ttttactcaa ccaccagcac gttttagtga ggctacgttg attcgtgcac
    16681 tagaagaaaa cggggtaggg cgaccttcca cttatgcacc aacacttgat acgatccaaa
    16741 gacgctacta tgtaaaattg acacaaaaaa gatttgagcc gactgaacta ggagaaattg
    16801 tcaattcatt aatctgtgaa ttcttccctc aaatcgtcga tatccatttc acagcagaaa
    16861 tggaaggaga tttggataaa attgaagaag gcacggaagc gtgggtcaaa gtggttgatc
    16921 gtttctataa accgtttgaa aaagaactga cgaatgcgga agaaaaaatc gaaaaaattc
    16981 aaatcaaaga tgaaccagca ggattcgatt gtgatgtctg tggacatccg atggtgataa
    17041 aattagggaa atatgggaag ttttatgctt gcagtaattt tcctgattgt cggaatacga
    17101 aaccaatcgt aaaagaaatc ggtgtgactt gcccagtatg tcatgaagga caagtcattg
    17161 aacgaaaatc taagaaaaac agactattct atggttgttc ccgtttccca gaatgtgaat
    17221 tcacttcttg ggataaacca gtgggcagaa attgtccaaa atgtgacgga tatctggtcg
    17281 agaagaaagt caaaggcggt aaacaagtag tctgtgtaaa tggagattac gaagaagaca
    17341 tccaaaaata atagaaaaga ggttctttca ttgaaaatgg taaatgttgt tggagcaggg
    17401 cttgccggaa gtgaagctgc ttggcagatc gcacaagcag gagtccctgt ccgtttatat
    17461 gaaatgcgtc cagtcaaatc gactgaggcg catcacacaa gtaattttgc tgaactagta
    17521 tgttccaatt cattaagagg aaacagtttg gctaatgcag tagggttatt gaaagaagaa
    17581 atgcgccgat tgaattcggt agtaatcact tcggcagatg aaacagcagt gccagctggt
    17641 ggtgccttag ctgttgaccg cgattctttt tctgaaacaa ttacccgaaa agtcaaagag
    17701 catccattag taacagtgat aaacgaagaa attactgaaa taccggaagg aatcaccgta
    17761 gtagcaacag gacctttgac ttctcatcca ttagcagaaa gcatcaaagc attcaatggt
    17821 tcagatggtt tttatttcta tgatgcagct gcaccaatcg tagacaaagc tacgatcgat
    17881 atggataaag tatatttgaa gtcccgctat gacaaaggag aagcagctta cttgaactgt
    17941 ccgatgacag aagaggaatt caaagctttc catgaggcac taatcaatgc cgaagtggca
    18001 gaacttaaat cttttgagaa agaaaaatat tttgaaggat gtatgccaat tgaagtaatg
    18061 gcacagcgag gattcaaaac gatgcttttc ggacctatga aaccagttgg attggaagat
    18121 cctaaaactg gcaaacgtcc ttatgctgtt atccagctgc gtcaagacaa tgctgcagct
    18181 tctttataca acatcgtggg ctttcagact cacttgaaat ggggcgagca aaaacgtgtt
    18241 ttccggatga ttcctgggtt agaaaatgct gaattcgttc gctatggtgt gatgcaccga
    18301 aacagcttta tgaattcgcc agaattgctg aaaccgactt accaatcaac gaaacgcgaa
    18361 gatctgttct ttgcaggtca gatgactggt gtagaaggct atgttgaaag tgcagcgagc
    18421 ggactacttg ctggaatcaa cgccgcacgc ttagcaaaag aaatggaacc agtcgagttt
    18481 ccacaagaaa cagctattgg aagtatggct tactacatta ctcatgcgga aggaaaacat
    18541 ttccaaccga tgaatgccaa ctatggtctg tttcctgaac tgccagagcg cattcgagac
    18601 aaaaaagcaa gatatgaagc aattgcacaa cgagctttaa aagctaatga ggcaataaaa
    18661 acagaattag aaaaaactgc aatcccaaat gagtaaggaa actccatgaa gagggtgaga
    18721 cggatagtct cgctcttttt
//
LOCUS       DACGDM010000043        18544 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.044, whole genome shotgun sequence.
ACCESSION   DACGDM010000043 DACGDM010000000
VERSION     DACGDM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.044"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(102..1589)
                     /locus_tag="IXR05_001649"
     CDS             complement(102..1589)
                     /locus_tag="IXR05_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260153.1"
                     /translation="MQVKKKIILSILLAIIAGLYSINYFRNVHTISTSGDIAFHFARV
                     KGLSSIFSGPINFTTFNHYGSGVNYFYPYLTFFPAVIFYWISNNLIVSYILYVWLLNV
                     CTIMLMFHYGLKFLKRIDAAFIFSCLYTFYGYRTIDIYHRSAIAEAIALTVIPIVMYY
                     AYALIYEKKPCAIPLAVSMSLLIYTHVLSTFMSVIAVGLLVLGGFVVSETRKKESIRL
                     IVELSKAVGMTILLTAYFWYPMFRQIMVQSINEPDKTTLQHQALNVSDSLIGAMNNDL
                     TTFTVGIIGIISLICPLFFFKGFNRKEKVIYLSAVVSWLLSTKFFPWSLLQNTPIQMI
                     QFPWRILGFQVLFGSLILSFVFMKSTSAKQRKVVNITAIVLLLLAVSAATKANYEHKV
                     VTQRDHLVMNQENLIRYTTLLPGGLYDYAPTEALQYKEHLQNHEVRIGKEWHTMPYQV
                     MDSKIVYTVHESKGQKITLPVFDYWGTVAKVNGQKREIDNRTSVD"
     gene            complement(2144..2707)
                     /locus_tag="IXR05_001650"
     CDS             complement(2144..2707)
                     /locus_tag="IXR05_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAQ4260154.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(2722..3765)
                     /locus_tag="IXR05_001651"
     CDS             complement(2722..3765)
                     /locus_tag="IXR05_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260155.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(3898..4302)
                     /locus_tag="IXR05_001652"
     CDS             complement(3898..4302)
                     /locus_tag="IXR05_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4260156.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(4535..5170)
                     /locus_tag="IXR05_001653"
     CDS             complement(4535..5170)
                     /locus_tag="IXR05_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4260157.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(5436..6488)
                     /locus_tag="IXR05_001654"
     CDS             complement(5436..6488)
                     /locus_tag="IXR05_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260158.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(6501..7439)
                     /locus_tag="IXR05_001655"
     CDS             complement(6501..7439)
                     /locus_tag="IXR05_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4260159.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(7890..8540)
                     /locus_tag="IXR05_001656"
     CDS             complement(7890..8540)
                     /locus_tag="IXR05_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260160.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(8640..9149)
                     /locus_tag="IXR05_001657"
     CDS             complement(8640..9149)
                     /locus_tag="IXR05_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAQ4260161.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(9350..10219)
                     /locus_tag="IXR05_001658"
     CDS             complement(9350..10219)
                     /locus_tag="IXR05_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4260162.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(10239..11360)
                     /locus_tag="IXR05_001659"
     CDS             complement(10239..11360)
                     /locus_tag="IXR05_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAQ4260163.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(11362..11757)
                     /locus_tag="IXR05_001660"
     CDS             complement(11362..11757)
                     /locus_tag="IXR05_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4260164.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(11776..12573)
                     /locus_tag="IXR05_001661"
     CDS             complement(11776..12573)
                     /locus_tag="IXR05_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010238514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4260165.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(12575..13363)
                     /locus_tag="IXR05_001662"
     CDS             complement(12575..13363)
                     /locus_tag="IXR05_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260166.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(13377..13853)
                     /locus_tag="IXR05_001663"
     CDS             complement(13377..13853)
                     /locus_tag="IXR05_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4260167.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(13925..16582)
                     /locus_tag="IXR05_001664"
     CDS             complement(13925..16582)
                     /locus_tag="IXR05_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4260168.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(16601..17005)
                     /locus_tag="IXR05_001665"
     CDS             complement(16601..17005)
                     /locus_tag="IXR05_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HAQ4260169.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(17237..17494)
                     /locus_tag="IXR05_001666"
     CDS             complement(17237..17494)
                     /locus_tag="IXR05_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAQ4260170.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(17619..17951)
                     /locus_tag="IXR05_001667"
     CDS             complement(17619..17951)
                     /locus_tag="IXR05_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260171.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         5861 a         3751 c         2742 g         6190 t
ORIGIN      
        1 ttaaaagaaa gaggtaacta cataaactaa ttaaaaaagc taacttcata gttggaggat
       61 aaatggaaga aacttcaatg attgtttctc cttgtgttcc ttcaatcgac actagtccta
      121 ttatcaatct ctcttttttg tccatttact tttgcgactg ttccccaata atcaaataca
      181 ggaagcgtta ttttttgtcc tttagattca tgtactgtat agactatttt cgaatccatc
      241 acttgataag gcatagtatg ccattccttg ccaattctta cttcatgatt ctgcaaatgt
      301 tctttgtatt gtaatgcttc cgtgggtgca tagtcataaa gtcctccggg aaggagtgtc
      361 gtgtaacgaa taagattttc ttgattcatt accaagtgat ctctctgagt gacaacttta
      421 tgttcatagt ttgcttttgt tgcagcagat acagccaaca gtaataaaac aattgccgtt
      481 atattaacta cttttctttg cttagctgat gtgctcttca tgaaaacgaa cgataaaatc
      541 aacgagccaa acagtacttg aaagcctaag attcgccaag gaaattgaat catttgaatg
      601 ggtgtatttt gtaataaaga ccatggaaaa aatttggtgg ataagagcca agagactacc
      661 gcactaaggt aaatcacttt ttctttgcga ttaaatcctt taaaaaagaa gagtggacag
      721 atcaaagaaa taataccaat gattcctacc gtaaaggttg tcaggtcatt attcatcgca
      781 ccaatcaaac tatccgagac atttaatgct tggtgttgta aggtcgtttt atctggctca
      841 ttaatcgatt gaaccatgat ttgtcggaac atcggatacc aaaagtatgc tgttaaaaga
      901 atcgtcattc ctactgcctt tgacaactcc acaatcaacc ggatgctttc tttttttctt
      961 gtttcactta ctacaaagcc gcctaagact agtaagccaa cggctattac actcataaaa
     1021 gtggaaagaa catgtgtata aatgagtaag ctcatactga ctgctaatgg aattgcacat
     1081 ggctttttct cataaatcag tgcgtaagca taatacataa ctatcggtat aaccgtaagt
     1141 gcaatcgctt cagcaatagc agaacgatga taaatatcaa tcgtacggta cccataaaat
     1201 gtatataaac agctaaatat aaaagccgca tcgattcttt ttaaaaattt tagtccataa
     1261 tgaaacatca gcatgatagt acaaacattc aatagccaaa catataagat ataactaacg
     1321 attaaattat tacttatcca ataaaaaatg actgccggaa aaaaggtcaa gtagggataa
     1381 aaataattca ctccgctccc ataatgatta aacgtcgtaa aattgattgg accagaaaaa
     1441 attgaagata accctttgac tctagcaaaa tggaaggcaa tatcccccga tgtagaaata
     1501 gtatgaacat ttctaaaata attgattgaa taaagtccag caataattgc taggagaatg
     1561 gacaatatta tttttttctt tacttgcatt acttaattat atactccttt catggattgc
     1621 tttatctagt ataacttaaa ttttaaataa atcgttattt atttttactc tcacttaaaa
     1681 aagcactaaa attataagag agggaggtaa tggtctgaac accaagaatt gttccaacat
     1741 cgaattgctt aactaatgag ttcaaagctt aattatgtgg ctcttatatt taccgagcgt
     1801 ggattgcgat ctctttagcg aaacaaacat ctttcataaa aaaaacagcc atatccgctt
     1861 tcttggatat gactatttac tactacttta ctatctttca ttcttcttgt ctcacttatg
     1921 ataaggcgct gcgtatcatg agtgaatgat attaggaaaa cttcataaaa taaatctttt
     1981 atacatttcc acttctagat ggtcattcat gttagaagaa tcaaactatt tttttactgt
     2041 cgtaataata ttaaaacact agaacaaatc aattaaattc cataaaatat aaataataga
     2101 cctagcatca tctggtataa aatggatgct aggtccgtta tatttactca aaattgattc
     2161 tacgaataga tcttcttatc atttctattt tagtagtcat gcgttgttgt tcttctaaag
     2221 gtggtaatgg tataagtagt ttagataaat ttgtaccatt tacatttggt tgcccagttc
     2281 cgtaagaaat tttttctaat aacttccaat ataatggcga gtctaagaag cagtctacgt
     2341 attctgataa taatttctca actaacctaa ttcgaatcaa gtaagaagca aaaacagatt
     2401 cctcacttat ttccttaacc aagaaacttt ttcccatagt tcctcctgtc cttgctatca
     2461 aaatgtcatt ttcttccaat cttaaatcaa ctagtttaga attactaata tcacagtaag
     2521 gcacactgga ccaatttaca cgtccctctt gtatatctgt gattctcaaa aacttaacat
     2581 tgccttgttt tttcgccgaa tctgtatagc catattgaat cttagtagaa atacttccta
     2641 aataaaccca tagtcgaaca tcgctagatg atttttcttg tcgttcttta tgaacaacag
     2701 tgatcatctt gagttgtccg actatttttt agttgcagca atctttttgg gacgcttatt
     2761 tgcatgaagc aacgttgcta agtctagtaa taaaacattg gctaacacag gattggcttt
     2821 ctcgcgatac gctgcggcgc cactttcaaa caatactgct agacgatctt ctacaacaac
     2881 gatttgttcc aaatacggtg gaaatttgat tcgttttagg atccggctag gagagtcccg
     2941 ctcggacact aagagttccg aggtataagg accataagaa cgactggcta agagataatg
     3001 gccataaaaa gccacacctt gaatcttatc agatgttttt ctgctcattg tcacggttgg
     3061 ttggattttg tctttgcggc gaattgctgt tttcatttca gctatcgtcg gcaatagata
     3121 gaaagtcaac tgtccttcac cttttagtgt gaagttgcca gataccagtt gatcattgtt
     3181 ttgagtcaaa tacgatgctt gtggaatctc tgagagatca gttgtcagcc aataagcgat
     3241 tggctgtccc gtctcttcag atgtatctgc taagatatcg atcaaacgta aagcggctac
     3301 tcgtccagta gcagatcctg tgattgtcaa ccataaaagt tcccgttttg tatcatatac
     3361 taagccccct acatgtggcc gtttaggtaa aatcagcagt ttgatcggct gtcctgtttc
     3421 tctatccagt acatgaataa tagaatgatg ctgatggtca tagcagtagg cagaaataaa
     3481 cacaaaatct tgagaaaaag ccaacccttg cggcgtcatc cattgacaaa cctcattttc
     3541 gccggtttcc ggcaccacca ttcttgtttc tgttaatcca ggaatgttat attgttttgc
     3601 ttcagccttt tcccaagctg cttgaacaat aggataccgt tttaactttt tttcaatatc
     3661 ctgatgtatc cgttgctgct tccaatgctt aaactttagg acatagtaaa caagaaggcc
     3721 aatgaccagc aacactaaaa tcattattgc tacccgctgt gtcatttttt tgcctccttg
     3781 ttctattcga tcaatcgtcc atataccgct attaattacc gtaactacat gtttctttta
     3841 ctagcgtttc tttataggat ctttcataat ctcatttata gtaacattaa gaatccctta
     3901 ttctactata gtcacttcca catcaatatt gcctcttgtt gctttagagt atgggcaaaa
     3961 tgcgtgggct tcttctgcga ttttctctgc ttggtccttc tcaagtcctg gcaaagaaac
     4021 ttctaaaacg accccgattt ggtagccccc atcttctaat tgaaataaag atacccgtgc
     4081 tttgacttca gaatcagact caagattatt ttcttccagc atgtgttgaa ccgcgccgtt
     4141 gaagcaagat gcgtatccag ccgcaaaaag ttgttccgga tttgtccctt cactatggat
     4201 tcctgggcgg tcgatcttca tgtgcatact tccgtttggt gcctcaactt cgccatcacg
     4261 gcctccacga ttgatcattg ctgtttcgta catttttttc attgagatca tcctttcttt
     4321 cgtcgttcta tattaagtgt aacgagtatt ttttaatctg acaaaggtaa tgcttgcatt
     4381 cggcgacatc agttagacaa catcgatgat cagtgataga agcagtttat ctatacaaaa
     4441 aaagaagggt tctatgatat ttggtgtcct tactcgcctt gagtaacaac accaaatatc
     4501 atagaaccac ttaatcagct tcacactgct ttttctactt tcgtagttga aaaaaactta
     4561 aacaaatcat cggcaaatag ttaaagaaaa aacttaatcg ttgaaagaag cccaattgct
     4621 taaagaaggc aaactgacta atcgacggaa tccgtgctaa tccgtaaaga cctgcaatta
     4681 gtaaactaat aactgttaaa acaagataaa aatggctaag cgtaccttga ccactttgac
     4741 gataaagcag aacaagtaac aatgggaaaa gtagaaagcc tgcatagcct agcccagaac
     4801 ctatattatg gatccaagtc gatagattac aagagctttc attcgtattg atactgaata
     4861 agccagtaaa aatacaatca cctatcccat ataaaccaac tgttgcaaca acaagtattg
     4921 caagtgtttt tgatgttcca acaaataggt gatacaacgc aggcaacgaa agaacaaaaa
     4981 aaagtccaga tacaactgac cagaccaaga aagcacgtct gactggacta tctacgtcac
     5041 caaacacact aattacggta gtcatttgat tcagtttggg ataaaaaagg ccaaggatat
     5101 acggtgtcga taaatcactc atcacaccta ataataaaaa ataaaaacca tatttttgca
     5161 aaaaaatcat tttcttcccc tactttttag tgattattcg atacatccaa caatcaaatt
     5221 ttttctcatt ttaacacata tttttattct agttgtcttt tgaacaatca ataacataaa
     5281 ggtgagtttc ttctacattt taaaaaatcg aatggcactg aagagttcag ttgtcagcat
     5341 caatctccta ctcaaaaagg caaaaaaacg taagtcagat gttgttgaca tctcacttac
     5401 gcatccattg attgaaaatt tcttagtaaa atctactagc ctaaaaattt gaagacttct
     5461 tctcgatcat acagtttaaa tactttctcg cataaaaatt gagtaattag tgccgcaaaa
     5521 acagggatga ctaaccaaca aagaacaaca agaaagccat ttagccctgc atctaaagaa
     5581 gccaacggac caacaagtcc gaccacgccg aaaccagcag aagcaggcgt acctgaaata
     5641 gaaaatagag cgacaggaat agctgtaatc actgcactaa ctaaacaagg aataagaatc
     5701 acaggttttc taaatagatt aggcatcatc atcttcatag cgcctaaagc aatcgcaatt
     5761 gtcacacctg acttattaac cttccaagag ttcactacta aaacaaaagt ggttgcagct
     5821 acgcccatcg cagccgcacc agcagaaaca ccatctagtt ggattgccat tccgattgct
     5881 actgttgaaa taggagagat aatcaaaaag gcaaaggaac aaccaatcaa gatagacatt
     5941 aacagcggtt gtaaggtagt gaagttatta atcaatgatc caattgcaga agtaattgct
     6001 gttacaaaag ggaataaata aaaaccaagt aaacctgcac ctacacctac aacaatcggt
     6061 gttaacacaa tcgacactga cccaaaacta tttccaatca gtaaaatcag cccgacagca
     6121 atcgatgctg tcagcatcgt attaataata tcgcctgtac cagcaccaac gtaaacaccc
     6181 gtttcaccca aatcaggtgt gaatttgact acaccagaac caacaaaaga agctccggct
     6241 acaaccatca ttctcatcgg atcaaatcca aattgtaagg caatcaaacc accaatgatc
     6301 aaaggtgttg ctagttgaaa aataactgct aactgtgcga tcgttaccgc aaagggatac
     6361 gcactaaaat attttaaaat ggcacctaat actgcattag gaatcaatcc aataatgatt
     6421 cctgttgctg taccagcgag gactttattc agaaaaattt tcggtgatat tttttgtgaa
     6481 gtttccattc aatctctcct ttattttacg ttcaaactat cttcttttgc atggacaagc
     6541 tcagtcaaga aatcacaata aggcgtcgca acaccatatt tcttcccttt tctagaaatt
     6601 gcgccattga tataatcgat ttctgttaat cgatggttct taatcaagtc ttgatacatt
     6661 gaaggataat gtaacccaat tgtttccggg tcaaaacaag attcacaatg tgcaatgact
     6721 tctgggacat ctagttcaat cttctctact gctgctactt tggcaaactc attgacaatc
     6781 gtcgccacca ttttatgagc agtcgatgtt tttcctagct cagccatatt aacgtctaag
     6841 attgtgcata gtccgttcat tgttccgttc acacatgctt tgcgataaat agaatagtga
     6901 atattgtcag aaaaatgagc atttaatcct gattcagaca atttgtctgc taattttttt
     6961 gcagctgctt cttttccatc acctaaattt tgtaattcta ctgaaccact tccaaataat
     7021 ttgacctgac caggaccttc aagacctgcc gtccacatgg tatttccaat atagatattt
     7081 tccattggta caaatttctc aataatatct tcatgcccga taccatttaa tagacataag
     7141 acctctgtat cttttttgat taatgattgg atatcctgca gcattttttc cagctgcatc
     7201 gctttggtaa atagaataat cagatcaact tgatcttctt tttctacttc ggattgaaga
     7261 acgattggta gttttgcttc tacctcttta ccattaaaat ttgcttgtaa tccatgttct
     7321 ttgatttgtt ggacatgttc tgcccagcca tcgattaata atacttcgtt cccactttgg
     7381 tgaagcatca acccaaagcg acttcccatt gcgccagcgc ctgcaattgc tattttcatt
     7441 gattcttcct cctttttctt tctattatac tcatttgaga atcttttcac aacctcgttt
     7501 tgttattctt ctcttattta tcatgtttat atccaccatt caagttattt tatcagcaaa
     7561 tcaataaaaa ctggaataga atcccaattt catcgtaaga gaaactagac tagcaataag
     7621 aaaatagaaa cattcataga aaaaatctca ctcctctgat tataaaagag ggggcattaa
     7681 cctcgtgtat actaaaacct tccattcatt cgatggatga ttttcttttt gtgaaaaaat
     7741 attcattgta gtacgatgtt gcgcaacaca gacggatggt attgcttatt atttattaaa
     7801 atcgaacaat acacttattt aaaaacttct ttcccagatt ttcttccatt tttacagtta
     7861 taactagtat tatcatgaaa aatagccttt tattgtctat gggaataata atttaaaatt
     7921 ggtacttttt tattaattag ttcatcgccc aataatctct ccagtttctt agcatctcct
     7981 gactcaaccg gaattatcca agcccagtct aaataatttt ttaaaatctc atcatatttt
     8041 gcaaatattt cattgccata ttccgtcctt aaaattatat tttcagtgcc agacaagtga
     8101 tttatattga gttgataaaa aagatctcca tctaaaaaaa tatcattaga agaagatttc
     8161 cccacagtaa tgaccattcc atcagctcta tgtgttacat acaaataatt gtatgacctc
     8221 atttcaccta atgaatcaat tatttcttgc cctttagctc taatatattg atctctatta
     8281 cctatctcac tcttatttaa caaaagtttt ttcatgtcaa atttaatcgg ctgttttatt
     8341 tttgtaaatt cgcttctact actaatccaa tccgagatta atttttcaac atgtcccaga
     8401 gtaaactctg atttattcgc taaatacttt ttttgttgta ttaaagacat ctttccccga
     8461 agctcaaaat tgagcctaca tcgattctct atctcttcaa aaagcatctt atcttcatca
     8521 ttcttatatt catcattcat aaaaccaatc cagctcctcg attaagataa tattttaatc
     8581 tcatacaaaa actagctctc atcaaaacaa ccattgtttt gatttctcat gaaatttctt
     8641 tatacttttc tccgattata aattcctaac cccttgagaa aattacgcat atatttatct
     8701 ccgcaaggct taaaatttcg ttggccttct tttctcaaaa atgccccgat ttcgcctttt
     8761 gatggataga tttctgcctc agcaaaaacg tctaaaatat catcagtggt catagacaag
     8821 gcgattttta atttttttag caacacattg ttgatatatt tgatttcctt gcttttttgc
     8881 ggcgtgtcta ctatcggctt atctttttgc ggaccacgcg ccaagagaat caggccattt
     8941 aggaatgcgt caaaaacttg gttgttgatg gttttttcat acacattatt ttctgcatta
     9001 tctttgttct tatcctgtac tttggtcagt accgcctgag cttcttcttt agtcagtggt
     9061 acaccgccta gctcaaaagc tttaatcaaa tccgtatctt tcaaatcaat cgcataacgc
     9121 aatcgcaata acctatcatt gttattcatt tgttcctccg aagtatttag tctttacttt
     9181 cttacgtact ttttgtcttg ctaagatttt taggatcaat gataaaaacc gcatcactta
     9241 tgataaggcg ctgggtatca tgagtgaatg atattgctga atacaaatag tccgaccaca
     9301 ttaagttgat cggacttcat aagcatttta ttgactaata cttttttgct taagaattga
     9361 ttctaacatc ttttgctaaa gttaagcatc ctatagttcc tgcattatct gctaacttag
     9421 gtgtgacaat gtattcttcg atatttggcg tatcgacata gccgttaatt agttctaaaa
     9481 aacgtctttg tactttcttt ttcagatgtt cttgttgcat gacaccacca ccaaaaatta
     9541 taatatctgg tgaaagcatc agggtcgtat tacaggcaca ttgtgcaata taatccgcct
     9601 cgatttccca gaacggatct tctatagaaa gatcttgtcc cttggttccc gtacgcatct
     9661 cgatagcggg tccagatgcc aacccttcga gacaatcatg atgaaaagga caagtaccag
     9721 agaaagtatc tcctgaatgt ctcttaacta acgtatgccc catttctgga tggctaaacc
     9781 cttcaacaaa aatcccatct tgtatagctc ctccaccaat tccagttcca acagtgtaat
     9841 aaacaacact ggataaacct tttccatgac ctgaaacata ctccccgtaa caagcagcat
     9901 tcacatcggt tgtccaggca attggaattt cgaaatgctt attcaacgtt ccaacaaaat
     9961 caaaattttt ccaggcagtt tttggagtag aggtgatatg tccataggtc tttgattcac
    10021 gatggatatc aatcggtcca aatgacccta ctccaatgct ttctaattgt tctttatagt
    10081 gattaaagaa atcaattacc aaactcattg tttcattcgg tgtagttgta ggaaaactca
    10141 ctctttctaa aacctttaaa tcatcattgc caatggcaca aacaaattta gtcccacctg
    10201 cttctattga gccatacatt tcttactcca ccgtcctttt atctaggaat tcgttcttcc
    10261 ctgtctaata gtttttcgaa aaactcatgt ggttcctttt ggtaccaata ggcaacagaa
    10321 gaaatatcgt cttgacgctc ataaagcttg atgtcatcat ttcctagggt ttggaaagta
    10381 acacgtaaat tttctttgaa actaatgggg tcgggtaaat gccagcggta caacccatgc
    10441 atcggtaaag catcatcgcc aaaaccatga actggatttg gattaggttt tccagcacta
    10501 aaataatccc gggtgtgatc tcttttagat tgaaaaggat agcccataaa tagcgtatta
    10561 aaattttgag catatgccct ttctccaaag ttctttttat ggaaagccca agcgccgcca
    10621 aaataatctt ctgctcctgt agatgttatt gtagggaaat cttcatctcc atctatataa
    10681 aacttaaatt ctccttcccc ccaccagtat ctttccaatg cgcacaaagc aaagtaggtt
    10741 cctacataat acccagtgcc tttgattcca tcaataaggg tgtaatcttt tccttttgtc
    10801 gtgatgggtt cacggttcca tttagcatga aaatacatcg catcatccgg tacttcagtc
    10861 aatgcataat taaatgtata aaaaatgtgc ttaataaact caggatgttc attcgttaaa
    10921 gtaatcttag ctttttttcg aaatggcatc tcaaaatagc aattcatccc tgatgttgga
    10981 ttcactacga ttggtaagga attcacttcg catcttgtcc caaacccatt acaaaaaaaa
    11041 tctcctaatg gactttctac agaaggagtg gattcatcat cccaataaat acgcaaaatt
    11101 aaatcacgta agacgaaact cccagcgatt gttttgtctg tcactgtcat ccaaaaatga
    11161 cgtaaaattc cagggccttc catttctgct aaagtaattg tctctccagc atttatcgga
    11221 acagaaggtg acccttttct cccaattcct agatgactcg ctgtcattgc cgctttccct
    11281 ttttcaccat ttttattttc tggtgaaata gttctacttt cctctccctt gtggagccat
    11341 atattattta aacaattcat tttattcgtc ctctatcctt tcttcacttt tttgattatt
    11401 catatagatg atttgttgtt gtgcctccgc aataattgct ccaatatcta aattatcatt
    11461 tcctaactgc aaagcgattg acattgccaa gggaagattc attcctgcaa ttacgtgcac
    11521 tctgtcagaa atataggtaa aaaacttttg atttacactt cctccagcca tgtcagttaa
    11581 aacaattatt tcgtctgtag tatccactaa ctctttaatt tgttcatcta tatcatcaat
    11641 ttcttcgaca tatgcacata agctactaat ttgattatgc atacctgtta aaaactctag
    11701 tgtctcttta aaaccctcag ctagtattga atggctagca atgatcaatc ttctcataat
    11761 tcaaatcctt ttcctttacg ctaatattcc aaatgcagcc ataaccatcg caaaaacaat
    11821 aacgagtaga atcaaaatgg tcatactgat ttttttctta ctgagtagat aatatgctgc
    11881 agcagtaata attactggaa ttaatgttgg taaaattttg tccaacattg gttggatttt
    11941 catactaact tcaccaaaag tgaatttaag tggcgttgaa acactgataa ctgaagcaat
    12001 taatgatcca actactgtta gccccaatac tgaagcagct tcagttaaat aattaatctt
    12061 ttcaccgtat tcagtaacaa tcttcattcc ctgcttataa ccaaattcaa agcctctcat
    12121 tcggaaaaag aagattacca tgattaaaat gaaccataaa aagattccta caggattatt
    12181 ttctaaagcc atataagccg caattgatcc catgatggtt gggatcatcg tcatcaaaag
    12241 agagtcccca ataccagcaa ttggacccat cgtaccaact ttaaagtcat taatcgcatc
    12301 ttttgcttct aatccttgct tttcctccat tgcaacacaa gcacctaaaa taatggctgc
    12361 cagccaaggc tgtgtattgt aatactgaaa gtgattattt aaagcttcga tgtattcatc
    12421 atcatctttg tataattttc ttaaaatagg tgacaatgcg taagtcacag atgcaccttg
    12481 ctgtgtttga taattaaagg tacaaactga catcaaccaa cgatagttcg ctttcctaag
    12541 atcctttttc gttacttgat atttttcgct cattttattc atcctcccca ataaacccaa
    12601 catcagaagc tcccgcagaa gcagtgattt gtgcatcttt ttcagctcta tgatacacat
    12661 taaatgctaa agcgaatcct atgatcgccg ctccaataat aggtaccttc aaaaaagcgg
    12721 ctaagaaaaa tccaacaagt aaataactaa tgtatcgacc tgtaggcata aagcgtaaca
    12781 acatcgcaat accaacagca ggcaacattt ttccggctaa tgttagccca tccataaacc
    12841 aattaggtaa aacatccaaa acgtaattaa cagcagactg tcctaaagta acggcaataa
    12901 atactggaat tgctgcagat aaaccaaaga aaattggccc caaccacaaa acactattca
    12961 ttttcttaaa ttctcgttta ttcgcatatt cctgtgattt gcgaacaaca aaaccattta
    13021 agattttgac aattacatct agttgcaccc ctaacatacc tacaggtagt cctattgcta
    13081 atccggcttc tactccaagc tggctaccaa atgccgttgc aataattgcg cacgttccat
    13141 agtccggtac agatgagcca ccaaaaccgg caactcctaa tgacatcaat tgaactgtac
    13201 cgccaactat caaacctgtt tttatatcac ccatcaaaat tcctgtgaat aatccccaaa
    13261 aaactgcgta atttacaaag atcatcggaa tcccataata atcaacatgt ttaataaatg
    13321 ctaatatagt cagcataata atttgaaaaa tagtaaaatg cattatcctt actcctttat
    13381 cctaattttg attgaatttc ctgtgcctta tccgccggaa caaattgtgt aacaatttct
    13441 acaccagaat ccaacaattt tttatacgtg ctgatatttt catctgatgc ataggctcta
    13501 gaagatagct gtaatgcatt atctttaaca acagtaccgc caacaattag tcggtcaatt
    13561 ctaataccgt tatctactaa atgaaggatt gtttccggct ctttcacgat gacaaatact
    13621 ttttcctgat cgtatttccc ctttttaaaa ttcgcaatcg ctgtttcttc agtgataatt
    13681 gatacagcca ttccagcagg tctagctaaa cgcatacttg atttttggat gtcgttattt
    13741 gcgacagaat catcgatcac catcactctg tttgctttag acattggtgc ccattgcgtg
    13801 acaataatcc catgcaataa acggttatca actctcgaca taacaatact cataaatact
    13861 tcctccttta tctttcattt tcttacaagc aattaccatg ccaaaacaaa aagaacttga
    13921 taaatcaagc tctttttaca taatcataaa cgtatttaac ctcatgaatc gggatgtcga
    13981 cactataata atgttcaacg acactgaaag attgcttaaa atgtgtctga aatttttgaa
    14041 attcctcact cgtttcattg aaataaattt catcttccaa agtattttgt tttactaatc
    14101 gttcaattaa gcaactaatg tgaacatata atccgaaaca cgtattatta tcaaatgaaa
    14161 ttcctagatc attttgtaag atgtatatag catctgaaac ccgttctaat aatttagtcg
    14221 gatttaatat ggtcaattgc tccattaaat tcgttagact aaaattcttc agaatattat
    14281 tgttcaaaac tttcagttca ttatcattaa agtgtctatt caattgattg gagaatttac
    14341 ttatattcat tcctaaaatc atatcttcaa ttgaaaagaa ttctacatct tctagatgtg
    14401 gatttagtgt tccaacaata aaaagaatat tgttctcttt acgaagctcc gataaatagt
    14461 tttcattcac taaagagtaa tagtcacacg tttctatgac aagatcagta tcccttggaa
    14521 agctatcttc aagtatcttt tttaatttaa acgaagttcc taatccgctt gcacaagaac
    14581 agacaatcat atccttctta atatttgatg attcataaat ataatccaca ttttgatttt
    14641 cttttacttg ttcaagaatc tgtttaagcg gtaaatctaa taatatctga tttgcaacat
    14701 caatagccat tcttgttgaa acattgttta gtagtccgaa ttttttttga gcgtctagtt
    14761 ccaaatttag ataaattttc tccagtgaac ccatatcaac aagtaaaata atttcttcat
    14821 atccggtaca ctcttgtaag tatctattaa ttttgtctgc aatctcacta cttgaagtca
    14881 ttagtggcat atcaatggcg tcgtatatat atctctcaac gatcctatta gcagtacttg
    14941 ctatacaggt tgccgttaga tctccatgag ccaaaatcag tgctaaacgt ttttgctgaa
    15001 attctttact acacattaac ttaaataaaa taaccaaaac atttttttga atttttgtta
    15061 aataaatatc ccctatttga ataaaacgat tgactaattg aacttctcga ctacaccaac
    15121 tattaatatc attgatgaag gaatataatt tatcgtccga tgttaattgg atttgataaa
    15181 tccaagaatt caaaaagata gacgttattt gaagataata atagtcaaat tctatttgaa
    15241 aatctctctc tatttcctta acatactgtc taaatcgaat ctcttgatag gtgggatatg
    15301 ttaaagctga attattttgg atatcaacat tcttttgtct aaaatatcta tcatatttct
    15361 caaaaagctg ctgcttatca gtgtctttct tccacgtttg ataaagatac tctataagtt
    15421 cgttgatatt aaaaacttcg tctacttttt ccaaatcatc catttgaata tattttaatt
    15481 cattctgtct tttcataacc ttcatgccgt tgaaattcac ccattgtggt aaatgataca
    15541 tctgaatata aagttcttcc aaatcatcta agaaataaaa ggcattggca caggtcaatt
    15601 gaatgatatt tttcaaattg ccaacatttt cactaaagcg atagtttaat aaaaaatcta
    15661 ataattgttg agatatcagt attttctttg ctagtctttc ttcttctgat ttaaaaaata
    15721 tcttgattaa ctgttttctt tcataaagag aacgactgtc taatgttgga agtgttagct
    15781 ttacaggtat tcttctcaac aaagttgata atagtttatc ctcaggtggt tctgatgttg
    15841 caaatataat ccagcaactt gatgtgtacc agttttcatt atcacccatc cgatgaaatt
    15901 tcctcgtatc cataaactga aaaagtttct cctgacattc attgctcaat gcatgaattt
    15961 catctaaaaa taagactcca ttattagcta attctgctaa accctttctt ccatcttcgg
    16021 ctcctgtata tgcacctttt acatgcccaa aaaaattgga caagaaaagt tctggattat
    16081 tggcatattc actacaatta actgaaatga aagatgcctt ctcttctata taattattgg
    16141 ccaacaaatc cttatacaca taatttgcta aatagctttt tccagttcca gtctcgccat
    16201 gaagtaaaat gggtaagcca tttggcggat agtagattgc tgctttaatt tgagcaatta
    16261 catttcgcag acttccttga cttccgataa ccctttctat tccaacccta aaagagctat
    16321 cataccattt ttccgcttcc tctgaagagc taaaaatttg ttgatttgga actttctccg
    16381 gtaaagaaaa gaagattact ggacgagtat tgatttttcc aaattctcca tcttttacga
    16441 attcattcaa atattgagag acaatattac gactaacatt taatttttca gatattttct
    16501 gtgctgtatt gttcccccat ttatttttaa tctcagagtt ctctatgaca taattgacaa
    16561 tgcgttcttt taattcttcc atcacagcac ctcctcgaca ctattcgaat tttgccgaca
    16621 gtatttttcc ataaatatga cttgctaaaa aggctttgtt tagatcattc aattggaacg
    16681 ttgcttgttt tgcttgatcc gctaagacgt tgaaaagata ctctggcgaa atcgcatacc
    16741 ccaaaatatc aacgattgtt gcaatcagat cttcttttga ttcttcatct gaaagtaatt
    16801 cacgatacaa catcgtttgt ttgcttactg tgtcatattc ctctaaggat tcatctgcta
    16861 aaagaaccac ttgttccaac aaacggtcgg ataaatattt atagaaaatc agccccaata
    16921 aataattttt atattctgac gcatccattt tactacggag attatctgcc gcactaaata
    16981 acttctgatt taattctgca cccaaaaaga tacactccta tctcttattt aaagttgcta
    17041 tataccctct tattttagca tactcagttt tagaaaaagc aaaaaaataa agaaacttat
    17101 tcttgataac aagctacgtg acgtatatcc ctaacacaaa aatagccata tcctttggtt
    17161 tggatacggc tatttgatat tactcattca attatcaaat cacagtaggt gtgaatctca
    17221 tcgggatcgg caatatctac ttctgattag gatcaaaggt gattttctca ataaaggtgt
    17281 gatacaaagc tttaacttgc ttcttctcac tctggataag aaagcaatcc aaactagtca
    17341 atatctgttg gacatctttg acttgaatcg gttccccttg ttgttgaaag atccctaaga
    17401 tttcattctc tcgaatttgt aactgtcttc gtttttcagt caattcattt aaacgatctt
    17461 ttaacatcgg aaacaattcg ggactatctt ccaaagcagc ttcctgtttt tgctctaata
    17521 gttagatttt gcgtaccatt ttcttctttt attttccttc gattgctgat tttaatatag
    17581 tctaaaggaa atttatattt attgtattct ttataacttc aagagaactt cgtttgagta
    17641 ttactgtatt tttttaattc cataagaaaa ttagttatta cctgccacct aatcagcaaa
    17701 tctgaacctg agtcaatata attaatatta ttttccatct ccaacattgt aagtactgtt
    17761 ggtgttaata tagggacttt gtacaattgt atttttttga ttttatcatc tgcacaaagg
    17821 agatttttta aatctaatcc ttcttttatt tcaaaagttg aattttttaa atctataaga
    17881 gtaaaaccaa ttccttcata ctgaatttct gaaaatcgaa tttttctccc agttgataga
    17941 tcaaggggca gaaaaccttt tattacattg tgagtgtcac catcatttac aatgtcatta
    18001 ggaattttga ttttagaatt ctgtggagca cctattggaa gataataatt cattataatt
    18061 ttgtagtctt catgaggaaa taaagtactt ttaggattgc taagatattc tcgtaccgaa
    18121 tctaagaatg gcttatccat tgaatcttca tccccattta aactaaaaaa cattcctaca
    18181 attgcttttg caactctaag tgaattcatt ttctttattg aatgtgttaa atcagactta
    18241 ccattcttta aacttgtatt gttataaagg aaatttttat tgtcttctgc aaatctaata
    18301 tattcctcaa catactcact accaaaaaaa ctattacatt tactacataa cgtattggaa
    18361 tggcaacagt ttttttgaca aattttataa ggtgcagaac ttctttccgt atgctattcc
    18421 gattgtcctt gacaatgagc ctcctcggat gtgacgatct tcggcaggag ctaacagtta
    18481 aagttagact gcctcgctag cgttagcaca tccgagctca ttatcaagga ttcgctgcgc
    18541 caat
//
LOCUS       DACGDM010000044        18423 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.045, whole genome shotgun sequence.
ACCESSION   DACGDM010000044 DACGDM010000000
VERSION     DACGDM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.045"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IXR05_001668"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IXR05_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAQ4260172.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IXR05_001669"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IXR05_001669"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAQ4260173.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="IXR05_001670"
     CDS             complement(2169..2906)
                     /locus_tag="IXR05_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4260174.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="IXR05_001671"
     CDS             complement(2997..3524)
                     /locus_tag="IXR05_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAQ4260175.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="IXR05_001672"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="IXR05_001672"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAQ4260176.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="IXR05_001673"
     CDS             complement(4401..4886)
                     /locus_tag="IXR05_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAQ4260177.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="IXR05_001674"
     CDS             complement(5039..5236)
                     /locus_tag="IXR05_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260178.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IXR05_001675"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IXR05_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAQ4260179.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IXR05_001676"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IXR05_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAQ4260180.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="IXR05_001677"
     CDS             9211..9423
                     /locus_tag="IXR05_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAQ4260181.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="IXR05_001678"
     CDS             9425..11104
                     /locus_tag="IXR05_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4260182.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="IXR05_001679"
     CDS             complement(11358..11558)
                     /locus_tag="IXR05_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4260183.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..11851)
                     /locus_tag="IXR05_001680"
                     /pseudo
     CDS             complement(11708..11851)
                     /locus_tag="IXR05_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(12086..12748)
                     /locus_tag="IXR05_001681"
     CDS             complement(12086..12748)
                     /locus_tag="IXR05_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4260184.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
     gene            13112..13199
                     /locus_tag="IXR05_001682"
                     /pseudo
     CDS             13112..13199
                     /locus_tag="IXR05_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ErmCL family antibiotic resistance leader
                     peptide"
     gene            13257..13988
                     /gene="erm(A)"
                     /locus_tag="IXR05_001683"
     CDS             13257..13988
                     /gene="erm(A)"
                     /locus_tag="IXR05_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HAQ4260185.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(14114..14896)
                     /locus_tag="IXR05_001684"
     CDS             complement(14114..14896)
                     /locus_tag="IXR05_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HAQ4260186.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(15050..15427)
                     /locus_tag="IXR05_001685"
     CDS             complement(15050..15427)
                     /locus_tag="IXR05_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4260187.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            complement(15434..17326)
                     /locus_tag="IXR05_001686"
     CDS             complement(15434..17326)
                     /locus_tag="IXR05_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4260188.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNMDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            complement(17323..18408)
                     /locus_tag="IXR05_001687"
     CDS             complement(17323..18408)
                     /locus_tag="IXR05_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4260189.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSEEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
BASE COUNT         5486 a         3821 c         2963 g         6153 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa tttcatatta tcaagagtaa attacaaaag
    11881 aatcatttaa atcaatactt tcactttgaa tacatgtatt tgaagtggaa ggtacttatt
    11941 tcaaaaatag taaaacctgt atcttaaatt acttaatagt aacataagat acaggctgat
    12001 tttttattca ttgttattta tactaaagca cccgatagct ctgaaaacaa tcacaaattc
    12061 aacttttcaa agccacagct ttaagttatt ttgtccagac aacccccatt gcccaaccca
    12121 ttttatggaa ttggcatcca ggcaacaact tttcatataa atcgtaataa ttttgttcag
    12181 ataggtactt atctgaagct aaatgctcaa gccatgattt agatgtgttg tgattataaa
    12241 ttctaatcgc attttttatt ccaaatttga aacaatgcgg taaaaactct tggattgccc
    12301 ctaatttata aacataggta ggcggtgtct cgacttcaga tacattatca agaataacta
    12361 ttcttccttc ctcattcaac agttccttca tttgctgtat tacgctggct atatcatcca
    12421 aatgatgaaa ggttgttcgg cttacaataa aatcaaactt ctcattaaaa ttaagttgtt
    12481 ctgcattcat attcagatag accgtatttg ttagttgacg tttagatttg gcaagatcga
    12541 gcatttgatt agaaatatca atccctacca cttcatcata ataacttgct aatttctcca
    12601 ctaacaaacc cgagccacat ccgatatcta atgctctgcc tttctttgga gacatattag
    12661 acacaaagaa tgaataatca ttcaaaagct cattcacgaa atcgtaatct tctgcaacct
    12721 tatcaaactg tgattctatt gtattcaaaa agatccccca ttcctacttt atcgacattc
    12781 tttcattact taccacttta gatgtttttt cgttggggat aaaacttccc tttagacaat
    12841 tttatccaaa gacaatacaa cagtgcaact ttattaaagt cactgtcctt tatcgcagcc
    12901 tttacttttt agtaaagaca gtggcttctc ttatcaagtt tcaaaacata ttattttgaa
    12961 gaaaacgtcc atctgaagtg tcaagtgcaa aattacatat aaaggtttat tctaaaatga
    13021 aaagatgata caatcatatt cagttacata aggaggtttc aattatgtgc accagtatcg
    13081 cagtagtaga aattacttta tctcattcat aatgaaaaaa atggaaagga gataaaagta
    13141 tgggtacttt ttctatattt gttattaata aagttcgtta tcaaccaaat caaaattaat
    13201 tggttataat gaacgcttaa tgtcagttca ttataaccag taaggagaag gttataatga
    13261 accagaaaaa ccctaaagac acgcaaaatt ttattacttc taaaaagcat gtaaaagaaa
    13321 tattgaatca cacgaatatc agtaaacaag acaacgtaat agaaatcgga tcaggaaaag
    13381 gacattttac caaagagcta gtcaaaatga gtcgatcagt tactgctata gaaattgatg
    13441 gaggcttatg tcaagtgact aaagaagcgg taaacccctc tgagaatata aaagtgattc
    13501 aaacggatat tctaaaattt tccttcccaa aacatataaa ctataagata tatggtaata
    13561 ttccttataa catcagtacg gatattgtca aaagaattac ctttgaaagt caggctaaat
    13621 atagctatct tatcgttgag aagggatttg cgaaaagatt gcaaaatctg caacgagctt
    13681 tgggtttact attaatggtg gagatggata taaaaatgct caaaaaagta ccaccactat
    13741 attttcatcc taagccaagt gtagactctg tattgattgt tcttgaacga catcaaccat
    13801 tgatttcaaa gaaggactac aaaaagtatc gatcttttgt ttataagtgg gtaaaccgtg
    13861 aatatcgtgt tcttttcact aaaaaccaat tccgacaggc tttgaagcat gcaaatgtca
    13921 ctaatattaa taaactatcg aaggaacaat ttctttctat tttcaatagt tacaaattgt
    13981 ttcactaaat taaagtaata aagcgttctc taatttcaca agaggacgct ttattcttcc
    14041 caaaaattgt tcaatattta tcaataaatc agtagtttta aaagtaagca cctgttattg
    14101 caataaaatt agcctaattg agagaagttt ctatagaatt tttcatatac ttaacgagtg
    14161 ctttcacctt tgaatatagt ccttcccact tatcatcaca ctctccccga tagccttttc
    14221 tagctatatc cagtaaagtt acatgctctt taggtaaaag aggtatagcc cattctgcag
    14281 cgacatcttt cgaggtaatt tcaccagtag tcactgtttg ccacattcga gctagggtta
    14341 aaattacatt acgctcatca ccttttatcc cctcaattag ttctggcaaa gaatccttaa
    14401 ttgctcttcg aatatctgtc aaaggtacgg agacaagtat acttgaagaa tcaggaccaa
    14461 atagagaaat actattcttt cttgcttgtg ctaaaacaat agccaaatca ggatcatagc
    14521 ttggttcctg aatttgtcca ttctcaaatt cacccctgag ccactcaccg tatataaatt
    14581 ctctttttgg aggatattgc caagggacaa cttcactcct atttataacc gtaacttcaa
    14641 gtggtctaac agaatccgta tttccaatct ttcctgatat agtcattagt ctttctgtta
    14701 gtttttttcg agttaattga ggtaaactat gattcacgac gactagaaca tctacatcgc
    14761 tgttaatgcg taaaccacca tttactgctg aaccaaatag atatactcca actattgaac
    14821 ttccaaataa atcttttacg atttttaatg tttgaatcgc ttgatttggt atttttccgt
    14881 taatcaaatt gctcatgatt tcacctcgta actgattatg ttcatataaa gtttatattg
    14941 atactcaatt tacttaccct agattggaca tatacctaaa tgactgttca ataaagctga
    15001 ccgttagcgt ttaagtacat cctttcacaa tttgtctaca gattaataat tattctttat
    15061 tatacagatc tccatataat ttttgaattt ggttctgtaa ttttttattt tctttttcta
    15121 attccattac tcttcttttt aaggttttaa taaggatttc ctccgaacga gaacttttct
    15181 tgggttttga gactacattt gctgttattt gacgctcacg aagggattcg attctttgcc
    15241 taatatcgtg ttccttataa agccatgatt tagaaacatt agcttccttt gctattgaat
    15301 taaaattaat aactttacct tcaatcgaaa atttagaaat cgctttgtct actttttccc
    15361 ttgtcttttt tgatttctgc ttcgccaaac gtacaatttc tgttgtattt ctaacttgtt
    15421 tatccattga taattacccc gtcaaacttc caatgatttg ttctaaacgc tctttaacac
    15481 ggctattagt ctctacttgt ctttgccatt gtttatcctt agctatggct aataactctt
    15541 ctgtacgctc taactgttct tcgtgctgtg gtaagaattg cttactggta cagaagtgag
    15601 tgcaatctaa gcatgcattc gcatgtggac aaccacctgc tactactggc aatctacaat
    15661 aaccatttgg aagcacttgt gcatttatat ttttcttgaa ccattgaagc tctacatcat
    15721 cgacttcatt atcttcatct agatcaagca catctccatt attggtaacc agtttttcct
    15781 gaaatttagt aaattcattt tttagagttt catcaaagat atgagcgtat ctgcttgtca
    15841 tttctgggct ttcatgcccc aaaaatttct gcacaatatg ctggggcatc ccgttgttaa
    15901 tcattcttgt tcctactgta tggcgaaagg catgggcatg gaatctataa atctcacctg
    15961 atttatccac tatattttgc tcataagcta atttatttaa ctcacctcta aatgtttctt
    16021 gttttaatgg cgatccatct tttcttggaa agaggtattc actatctgga aattcctctg
    16081 aaactttatc ttcccgaact ttaataagta aagctacctc tttagatatt ggaactatat
    16141 gctccttttt cattttccat tgataatact ttaaaaagaa atctccatct ttgtcctcta
    16201 atagacagcc ttttttcaag gtgcacaatt cacttatcct cattccacat tcttgaacaa
    16261 tcatagtcat cgtagctata tattcgggta atttatcaag atgactgttc aattgctcta
    16321 ggacgaattc atctataaag cgtggttttg ctcttggtat tttcggatag tcctcagaat
    16381 aaattaatat tttggaagga acatcatccc attctagcct aagaagggta ctaaatagtc
    16441 cttccaatat agagatcctc ccagttattg tactaggttt tattcccatc atgtttagtt
    16501 cacttaaata tgcttcaatt tccactctcg ttaattggtg tactctctga acttgtttaa
    16561 atttcatgtc cagaaaatta aagaactctt taagtctttg ggcaatatca cttacatagg
    16621 aaaagctatc catgttcaat ctcaacttac aatatctttt tacaagttgt ttaaaatatg
    16681 tattccgaaa ccctttaaag ttaattgtat attcatattg tgttgggtta accttatcat
    16741 ctggcaaagg taagttacgt ctatcccaaa cgtctttatc ccactcctct ccatcaaaat
    16801 aaaagttctc ataaaactcc ataaattgtt ttagattagt aacatagtag gaattagctt
    16861 ttacaggtgt tttttcttga ttagcagtaa tcttataatt agtagtggta attctaacac
    16921 cccgttttgt caaataagtt ctatactccg tcattgcttt ttcaatagga acttcagtaa
    16981 ttgaagtaat gctaggatac tttaaatcta agaaatctaa cattttatta attactgttc
    17041 cttttctaat ccagacagtt tttgcattcc atattccatt gtttaaatgg taaaaataaa
    17101 aatatttcaa ttctgttctt aaccacagat ttttaacacg ttcaaaacga acccaacgat
    17161 tccttaaagc aggattctta cttaattcta tggcagaagg atgtggacat tttcttatat
    17221 cccaactatt attagcccaa aacccctgca tttcttcatt cattacagct atttttttgc
    17281 taatctcact ctgactaata attttccttt tactagaagc attcatttct tatgctcctt
    17341 tctctcgagg tatttattaa actcattttt catatcctga tctgaaagat gaacataggt
    17401 atttaacgtt gtctgaacat gtgcgtgacc taatctcttt tgaacgaacg caacatccca
    17461 tccttcccta attagctgcg ttgcgtgagt gtggcgaagc atatgtgatg taaattctat
    17521 tccagtcctt ttaactattc ttctaactag atcaagaaca ctttggtact ttagtggttt
    17581 cccaaaatag ccttctttta aggaaataaa aacataatca tgctccaatt cctcactata
    17641 ctcatatatc aagtaatctg tataaagtga cataagttct ttactcacat gtattgttct
    17701 ttccttcctt aatttaatat aagcttcatt aacattaaca tctctaggtg ttaaatggat
    17761 ttgattgtcc caagtgacaa tatcttcaag cctaagcgat aacacttcac cgattcttaa
    17821 accaccctca tacataagca ttaaaattaa tttatctctt ttcgtatgac aagcatcaat
    17881 aatttgctta acttcctctg atctcaatgt tcttatctgt ttctttttaa cccttaactt
    17941 taagacattc ttttggtatc tacccttatt aacatgatgt aaaaatcctt tgaaatttct
    18001 tccctttgct tgtttaaata catcaattga tttaaattct cctaatctac ttaaataatc
    18061 aagaaaactc ataactacat ttaaaattgt attcactgtc gtttcttctc ttatggcttt
    18121 ttttgactga agatcaatta catttgatgc tgaaggatat ctcaaccaac ctacgaagtc
    18181 tgctaacaac tcaaagttaa tatcattaag aataacacct ctctgttcca tgaactcgta
    18241 cagcaacttt aaatgatagc agtatgcttt aatggtatta ggagacttac cagtattatc
    18301 taagtattta ataaatttca ttactggttc tattagctgg tattctttat ctagtaataa
    18361 atacaatgga tacggcttat tctccacttc tatcctttga accttcacat gttcccacct
    18421 ctt
//
LOCUS       DACGDM010000045        18011 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.046, whole genome shotgun sequence.
ACCESSION   DACGDM010000045 DACGDM010000000
VERSION     DACGDM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.046"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(27..725)
                     /locus_tag="IXR05_001688"
     CDS             complement(27..725)
                     /locus_tag="IXR05_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAQ4260190.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(718..2070)
                     /locus_tag="IXR05_001689"
     CDS             complement(718..2070)
                     /locus_tag="IXR05_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAQ4260191.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2293..3693)
                     /locus_tag="IXR05_001690"
     CDS             complement(2293..3693)
                     /locus_tag="IXR05_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAQ4260192.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3854..4591
                     /locus_tag="IXR05_001691"
     CDS             3854..4591
                     /locus_tag="IXR05_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAQ4260193.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4716..5195
                     /locus_tag="IXR05_001692"
     CDS             4716..5195
                     /locus_tag="IXR05_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAQ4260194.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5192..5959
                     /locus_tag="IXR05_001693"
     CDS             5192..5959
                     /locus_tag="IXR05_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260195.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6189..6758
                     /gene="lepB"
                     /locus_tag="IXR05_001694"
     CDS             6189..6758
                     /gene="lepB"
                     /locus_tag="IXR05_001694"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4260196.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6862..7464)
                     /locus_tag="IXR05_001695"
     CDS             complement(6862..7464)
                     /locus_tag="IXR05_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4260197.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7570..8039
                     /locus_tag="IXR05_001696"
                     /pseudo
     CDS             7570..8039
                     /locus_tag="IXR05_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8145..8729
                     /locus_tag="IXR05_001697"
     CDS             8145..8729
                     /locus_tag="IXR05_001697"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAQ4260198.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8732..9805
                     /gene="prfA"
                     /locus_tag="IXR05_001698"
     CDS             8732..9805
                     /gene="prfA"
                     /locus_tag="IXR05_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAQ4260199.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9798..10637
                     /gene="prmC"
                     /locus_tag="IXR05_001699"
     CDS             9798..10637
                     /gene="prmC"
                     /locus_tag="IXR05_001699"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAQ4260200.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10630..10809
                     /locus_tag="IXR05_001700"
     CDS             10630..10809
                     /locus_tag="IXR05_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260201.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10831..11856
                     /locus_tag="IXR05_001701"
     CDS             10831..11856
                     /locus_tag="IXR05_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAQ4260202.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12031..13275
                     /locus_tag="IXR05_001702"
     CDS             12031..13275
                     /locus_tag="IXR05_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAQ4260203.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13428..14375
                     /locus_tag="IXR05_001703"
     CDS             13428..14375
                     /locus_tag="IXR05_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4260204.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14509..15138
                     /gene="upp"
                     /locus_tag="IXR05_001704"
     CDS             14509..15138
                     /gene="upp"
                     /locus_tag="IXR05_001704"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAQ4260205.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15277..15519)
                     /locus_tag="IXR05_001705"
     CDS             complement(15277..15519)
                     /locus_tag="IXR05_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260206.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15640..15712
                     /locus_tag="IXR05_001706"
     tRNA            15640..15712
                     /locus_tag="IXR05_001706"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15673..15675,aa:Thr,seq:cgt)
     gene            complement(15831..16469)
                     /locus_tag="IXR05_001707"
     CDS             complement(15831..16469)
                     /locus_tag="IXR05_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4260207.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16592..17224)
                     /locus_tag="IXR05_001708"
     CDS             complement(16592..17224)
                     /locus_tag="IXR05_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4260208.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17575..17874
                     /locus_tag="IXR05_001709"
     CDS             17575..17874
                     /locus_tag="IXR05_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4260209.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT         6166 a         3154 c         3558 g         5133 t
ORIGIN      
        1 ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata gggcagatcc
       61 aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc caggttctca
      121 tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta aatgacacct
      181 tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa aggtcgttca
      241 ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt ttcattgaat
      301 tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact taacgtgtag
      361 tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta gtagtgacct
      421 agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat atagttgatc
      481 aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa gtcttgacca
      541 ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat actaacgatc
      601 tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa aaggtttccg
      661 ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag ttcataatta
      721 gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac gaagctgcaa
      781 tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt tgattttttc
      841 gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc cggcaacttt
      901 tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg ggatatccat
      961 atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc cgtctgcgta
     1021 attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa tcatatcgat
     1081 tacttgattg atacctacag gatttttgac aagtactaat gtacattttt tcccattgat
     1141 attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt gtttgatttt
     1201 atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat tgtagacatt
     1261 atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat ctgctgacac
     1321 attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt tgaagtcaca
     1381 atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat gcaagatgtg
     1441 atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt cacgatcttc
     1501 ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat tgaagattgg
     1561 tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt ctacaatcat
     1621 tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa tatttgtaaa
     1681 taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt catctatttc
     1741 taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag tcgatacaat
     1801 tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt gctggcgcaa
     1861 aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga caacgacgac
     1921 ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg ctagtttacc
     1981 tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg tttttccaac
     2041 tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga tttgctgacg
     2101 aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt ttcttattct
     2161 taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga tttaacaaaa
     2221 aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt ccctcttacc
     2281 tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc ctagatctcg
     2341 tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc caataaacat
     2401 cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc ctaaagataa
     2461 accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg tttgttcttc
     2521 tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca taaagacaac
     2581 gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga tgttatcttc
     2641 acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg ttcgaatccc
     2701 gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa tgatcagtgt
     2761 tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag tcgtaatcga
     2821 ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata aatggtcctt
     2881 ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag ctaacacagc
     2941 taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt tgtataatag
     3001 ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa tcaaaaacat
     3061 gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc cagtgacgtc
     3121 aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa cggcatcacg
     3181 ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc caaaaagtaa
     3241 ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac cagacaaacg
     3301 cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc gtcgtttaga
     3361 aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt gaaataatat
     3421 ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag tcgatagtcc
     3481 agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa catggctatc
     3541 tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca tcaatatata
     3601 ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct gtcctcgccg
     3661 ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac aatagtcgtt
     3721 tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca gataacaata
     3781 cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa aaagaaggag
     3841 gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa atcaaaaaat
     3901 aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag aagtaaagcc
     3961 taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg aattcatgtc
     4021 tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta aaagtgagta
     4081 tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga aaactgacca
     4141 tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa tggttttaac
     4201 aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct tcaatatgcg
     4261 attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg gaagtgccct
     4321 gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg atatccaaaa
     4381 gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct atgaacgctc
     4441 tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt gcgtgttcgc
     4501 tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag cttacttaaa
     4561 aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac gtaagaaaaa
     4621 aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag taaagtaagg
     4681 aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca cctattttga
     4741 agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt attgtgaata
     4801 gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca acaccaacta
     4861 cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc actacgacaa
     4921 gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca actgacagct
     4981 caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc aatccaagta
     5041 caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact gtagatgata
     5101 acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca ggaaataccc
     5161 aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc ttatcaacgg
     5221 ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc gtggatatac
     5281 gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac tttggcaaaa
     5341 ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg tttattttac
     5401 tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg tcactcagct
     5461 ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat cgatagataa
     5521 tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg acgaagatta
     5581 tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga tcaaaacaaa
     5641 tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc cttattacta
     5701 tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct actcggacat
     5761 ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac ctgtcggatt
     5821 gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc cttatcgtct
     5881 gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata gtcgtagcca
     5941 aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg ataaaaacgt
     6001 ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt atataacgag
     6061 aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt gtagaataaa
     6121 gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat acaagtagga
     6181 ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta ttagcggcta
     6241 ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat tcgatggacc
     6301 ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat gaacgaatgg
     6361 atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa cggatcatcg
     6421 gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat ggcaaaaagt
     6481 atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag ttacaaggag
     6541 aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc tttacgagtg
     6601 actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac cgcttgattt
     6661 caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga aaagttgttt
     6721 tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa aagaagctgt
     6781 gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct tggagttgct
     6841 cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa gcgaagcgtt
     6901 tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag agacaaagcc
     6961 cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga ctttcggatg
     7021 actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag gagctaaaat
     7081 ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta caagtgatag
     7141 aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt ggatcgttcg
     7201 gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca tagtttctga
     7261 agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa caagcccagt
     7321 tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat aagtagttag
     7381 ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat ggttagcgat
     7441 ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg aaattttaac
     7501 ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa gggagaatct
     7561 agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa gtgtgtccga
     7621 gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga aaaatatatc
     7681 gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata tttaggcttt
     7741 atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt atgggaataa
     7801 aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca gaaggttacg
     7861 cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac tactctatat
     7921 atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa gtttttccaa
     7981 atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa caaaagtgag
     8041 caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa atgctgaaaa
     8101 tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca caactatttt
     8161 ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc gcacataatt
     8221 atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca agagatggtt
     8281 taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata tttgaagaaa
     8341 cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg ctgatcgatg
     8401 aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg gacgaattgg
     8461 atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta tttgaaggat
     8521 caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc tgttggttct
     8581 gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt tatgaaggcg
     8641 atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa cattactttc
     8701 acccatcaat gattacagaa ggagaataag catgtacgat caattacaag caattgaaga
     8761 ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg atacaaagcg
     8821 ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag tttatcgtcg
     8881 ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg aaaaactgga
     8941 tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag aaaaagaagt
     9001 cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg ataaaaatat
     9061 catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg ctggcgatct
     9121 tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag tgatggaagc
     9181 taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg gagacaacgt
     9241 atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc cttcaactga
     9301 atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag aagctgaaga
     9361 agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg cttcaggtgc
     9421 tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact taccaacagg
     9481 gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa aagcaatgaa
     9541 aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg agtatgatgc
     9601 caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga cgtataattt
     9661 cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat tagatcagat
     9721 tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc aaacatcaaa
     9781 actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca cgggcttctt
     9841 cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt ttggaacgaa
     9901 aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca gaagaagaac
     9961 agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct cagtatttgc
    10021 taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca ctgatccctc
    10081 gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt gtaccgttag
    10141 aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa gcagcaagaa
    10201 aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta gcgaaagaaa
    10261 atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta ggaccagtaa
    10321 tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg aatgaatggg
    10381 aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt gctgagaacg
    10441 atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta aaatcaaatg
    10501 gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa atatttcagc
    10561 aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat gaacgaatga
    10621 tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt tattataaaa
    10681 aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt ttatccacta
    10741 ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag acaaaataag
    10801 aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga tgaaacagaa
    10861 ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc taccgaaaca
    10921 gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt gttttctgta
    10981 aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga acaagtaaaa
    11041 gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt ctggcctgga
    11101 ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt gacgggagga
    11161 ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt aatcgaactt
    11221 tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag tccaacgact
    11281 gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga tgatggagct
    11341 acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc catgcctatg
    11401 attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga atctcctgtt
    11461 gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg gatgaaatac
    11521 aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg gtcaactgca
    11581 gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc cgaaattgcg
    11641 gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc agtagaagcg
    11701 gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact tggattagat
    11761 ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat gaatcgcttg
    11821 aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg tcgcattctt
    11881 ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa ctaagcgtaa
    11941 ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg aaaaataaaa
    12001 ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt acaaaacgtt tgaccctgat
    12061 ctttgggctg cgatcgccaa agaagaagaa agacaagaac ataatttgga gctgattgcc
    12121 tctgaaaact ttgtctccga agcagtgatg gctgcacaag gaagtatctt gacaaataaa
    12181 tacgcagaag gttatccagg gcatcgctat tatggtgggt gtgaatttgt cgatatcgtt
    12241 gaaaatttag cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc gaacgtccag
    12301 cctcactccg gctctcaagc caacacggct gcttatctcg ctttggtaga accaggggac
    12361 acgatcttag gaatggatct ttccgcaggc ggacatctaa cacatggatc accagtcaac
    12421 ttcagtggca aaacctatca ctttgttgct tacggtgttg atccgacaac agaagttatt
    12481 gattataatg tggtacgtat tttagctaga aaacatcaac caaaattgat cgtagcaggt
    12541 gccagtgctt acggacgaac gatcgacttt gcgaaattca gagaaatcgc agatgaagta
    12601 ggcgcaaaac tgatggtaga tatggcacat atcgcaggat tagtagcagc aggacttcat
    12661 cctaatccag ttccttatgc agatatcaca acgactacca ctcataaaac attgcgtggc
    12721 cctcgaggcg gcatgatttt gacaaacgat gaagcattag caaaaaaaat aaatagtgcg
    12781 gtatttcctg gtattcaagg cggccctcta gagcatgtga ttgcgggtaa agcagtagca
    12841 ttcaaagaag cattagatcc tgcatttaaa gaatatagtg aacaaatcat cgccaatgca
    12901 aaagcaatgg tcaaagtttt caatcaagca attggaacca gagtcatttc aggggcgaca
    12961 gataatcatc tgatgttgat cgatgttcgc gagttaggta taaatggaaa agaagcagag
    13021 agcattttgg acagtgtgaa tatcactgta aataaaaact cgattccttt tgaaacacta
    13081 agtccattca aaacaagcgg tattcgaatc ggcacgccag caatcactac tcgcgggttc
    13141 aaagaagaag atgctgtaaa agtggctgaa ctagttgtca aagcattaca agcaaaagat
    13201 gataacgctc aactagacga agtcaaaaca ggtgtacgcg aattaactga aaaatttccg
    13261 ttgcataaaa aataaaaatt taaattccat tagtaaacag aaaagttcaa tgttgggctt
    13321 ttctgtttat tttttgggaa aacggattct ttgacaatat cggtgatgct ctctagtata
    13381 tgaggtgtaa ttttagtctt cacactaaat ctcagggagg aaaagtcatg actgatcgta
    13441 tctcgttaga aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat ccgcgtatct
    13501 atgaactagc accggaagaa ggaagagttt tactagaaga agtacaagaa tcacctgtga
    13561 acaaatattc cgtcgatatt gaagacttga tggtggatac tggcgaatgg ggaaaactca
    13621 atattcgtct cgtacgacca gaagggaata tggataaatt accagttatt ttttatattc
    13681 atggagcagg ctgggttttt ggcagtgctc aaacccatga taaattgatc agagaacttg
    13741 cggttcgtac gaattccgtc gttgtctttc cagaatatag tcgatcacca gaagcaaaat
    13801 atccaacagc aattgaacaa aattatgctg tgttgcaaca gctgaataaa ttagccaagt
    13861 caaaaaatct ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt ggtaacatgg
    13921 ctacagtcat gacgatctta acaaaagaac gaaagggcct cccaatatcc aagcaattgc
    13981 tgtattatcc agtcacaaac gctgattttg atacagattc ctatcatgaa ttcggagaaa
    14041 actatttttt gacaagagaa ggaatgatgt ggttttggga ccaatatacg acgaatgaag
    14101 aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa ctaaatgatc
    14161 ttccttcagc aatgatttta acgggagaag cggatgtatt aagagatgaa ggtgaggctt
    14221 atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca agtacgcttc caaggaatca
    14281 tccatgattt tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt gcagcaatgg
    14341 cattatctac ttcttggatc aagaaaaaag aataagcttt gcttgtccgc aggaaaactt
    14401 cttttcaaaa acggattttc ttaggaaaaa tggcgagttt gactagtcaa tcacttgatt
    14461 ttgttttaca attaaaaaga aacgacagaa caaaggagag cttaaaaaat gggcaaattt
    14521 caagtgatcg atcatccatt gattcaacac aaactaacta ttattcggga caaaaactgc
    14581 ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta tgttgatggc atatgaagta
    14641 tcacgggata tgccattgga agacatcgtg atcgaaacac cgatcactga aacaacacaa
    14701 aaaacgttgt ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg tattggaatg
    14761 gttgacggta tcttggaatt gattccagct gctaaagtgg gacatatcgg tctttatcga
    14821 gatgaagaaa cattggaacc acatgaatat ttcgtcaaac ttccagaaga cattgatgca
    14881 cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat catggcaatc
    14941 gatgcattga aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt agcagcacct
    15001 gagggagtaa aagctttgca agaagcgcat cctgatattg acatctatac agcttctcta
    15061 gatgaaaaat tgaatgaaca tggttatatc gttcctggac taggggatgc gggtgaccgt
    15121 ttgtttggta caaaataagt aaatacgaaa aagggtgtga cacaactttt gtcacatcct
    15181 tttttggtca tttttaacgt ttgatgcaga acagcttttt cacagctttc gtttgcatat
    15241 aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa atctttttta gttctttgta
    15301 gttaacgatt actacaccct tactttgcgt catcaagttc gcattttctg cagtttcatc
    15361 aatctcaaca acagcggaat ttttcaattg ctttgaaatc gttccagttt gcgacttgcc
    15421 gtgaattgtg aacattacgt gagtattgat cttgaatttt tcaccaattt ccgatggtac
    15481 gatagttgta tcaaattttc caaaagttgc cattttcata aaacctgcct ttcacatcaa
    15541 ttataccacg ttttatgaaa aatatcatga aattaaacta attttccatc ggactcttta
    15601 caatcagcca aatagagtat ataatttctt ttggataagg ccagcttagc tcagttggta
    15661 gagcaacgca ctcgtaacgc gtaggtcgta ggttcgatcc ctatagctgg cattaaaaga
    15721 gaagacagat atatcaagga tttttaatcc attgatacat ctgtcttttt gtttaaagga
    15781 aataaagtat gctttcttag caatagagca tgtattattt ctataaaaat ttaggagaat
    15841 aaaacgacta gcaatatagc tgtgaaatca aatatcacat gaactgccca acttgtaatg
    15901 atcgagttgc ttttaatggc agcttggttg aataacaatc ttgccacccc ttgtatcaaa
    15961 aggatgtgtg ctacagtgtg taaaatattt ccattatcat aagtactgta atggataaat
    16021 ccaaagatga ttgctgacaa gaaactagcg acaggaatgc tgaacttact agaaaaaata
    16081 gcgagaaaat acactgagaa caattcttct ccaagtatca tgataggcaa aataataaat
    16141 aataacgggc tgaaagcctc atttattgga ttgcctgtta aaccccattt caaaatttgt
    16201 tgcaaaaata ccgagactgc ggcactgatt actacattga taaaaaaata tttggctata
    16261 tttttgacag gagcgacagg tttcgagaac atttttttcg tatctttttt accaaaaaca
    16321 agtgtaaatg ctataaatcc agtgatagtt aaagaaaaaa tgctaataat ggatggcgca
    16381 aatagcaacc ctaacaaacc gagtacaacg acaatagtgc ccaatatccc ttttttaagt
    16441 tctatttttt ttcctaaaat gttattcatg ataataactc ctactattca gtttttgaag
    16501 atagagtcag tatacatgaa gagttaaaat aggcaatgtt tttttatgga tatttgtatt
    16561 gctaaaaatt tatcttatat attcattttg attatactac ttttatttgt aaaaattttc
    16621 tagcaaaacc aagtgcttgc aactgattaa gcgtacaatt ttttagatgt tccgagcgta
    16681 cttcaatcat ttcaaaggag ttgctactta aatcgatatt ttttaaatca gtatcaaaaa
    16741 agctagcatt ttctaaatca ttagtagaaa acattatttt agtgagggaa cagtctacaa
    16801 aatctgcgct tgataagaca gagtgctcaa aggtactttc ttttatgttt gaaccagata
    16861 aatttacata gtccatttta caattctcga ataacgtgtt cccaatataa ctttccatca
    16921 atttagtacc tgttaattta caattgacaa atttcacgcg atgcaacatg ctttttgtca
    16981 atatacagcc tgaaaaatca cagttttcga atatacagtc ggtaatctcc attctttgaa
    17041 aatcattgga agcaaaaaat gcatacttga aaatagattt gtaaataatt ggatggcaga
    17101 ttatttggtt ttcgatgacc tctttttgtg aaaggatatt atacagttca aaatcttcgt
    17161 tttcatagat atgaaaaaag gatcctttat tcaagcttgc ttcattaact ttaggaaaaa
    17221 tcatatttaa ttacctccat tttcataaag tcatattaac aaaagctaaa ccaacttaca
    17281 ttagcagaaa atgagatagg ttttcgcctt tttcgataac gatagtgtcg ctatctcttg
    17341 aaacgttctt agaattgccc tgagagacac aaattaggcg taattctaat aaaaatctta
    17401 gaataaaaat ttttactgat ttaatttaga atgtttttaa aataaaaatc gttgccataa
    17461 cagtgtattg aaaggtttta acaatccagt aatgatttaa aaaaatctag atgtagcgta
    17521 tactttgttt atagaatgta gtgggaagaa atatattttt gggaggaaat cgtgatgtct
    17581 aaaagtgaag aaatagaaaa catggtacta aaattatatg atctcgtttt aaatccagag
    17641 atcaaagaaa aggaacgtat acttttgata gacgcaaaga caggcttaga aaaaggtcag
    17701 tattatccta aagtcataaa taatttggaa cgtagtttac gtccgttagc aatcagggga
    17761 gaattgtcta aaccagtatc accgttttat atggagatat caacaatagg aaaatttgaa
    17821 aaagaattag gtcgaggaat ggcttcggca ccgattactt ttgggcattt ataaaaacga
    17881 gttattcatc tcaatgaatt aaaaagtata gtcaatctca taatgcaggc taggttcatt
    17941 tatttgaaca gagtctgtat ttttttattc taaataaaga aacagatgtt tctttatatt
    18001 gtattttatc c
//
LOCUS       DACGDM010000046        17994 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.047, whole genome shotgun sequence.
ACCESSION   DACGDM010000046 DACGDM010000000
VERSION     DACGDM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.047"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            11..733
                     /locus_tag="IXR05_001710"
                     /pseudo
     CDS             11..733
                     /locus_tag="IXR05_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            791..2830
                     /locus_tag="IXR05_001711"
     CDS             791..2830
                     /locus_tag="IXR05_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAQ4260210.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2939..4090)
                     /locus_tag="IXR05_001712"
     CDS             complement(2939..4090)
                     /locus_tag="IXR05_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4260211.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4244..4774)
                     /locus_tag="IXR05_001713"
     CDS             complement(4244..4774)
                     /locus_tag="IXR05_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260212.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4873..5223)
                     /locus_tag="IXR05_001714"
     CDS             complement(4873..5223)
                     /locus_tag="IXR05_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAQ4260213.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="IXR05_001715"
     CDS             complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="IXR05_001715"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAQ4260214.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="IXR05_001716"
     CDS             complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="IXR05_001716"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAQ4260215.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7626..8288)
                     /locus_tag="IXR05_001717"
     CDS             complement(7626..8288)
                     /locus_tag="IXR05_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4260216.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8472..10118
                     /locus_tag="IXR05_001718"
     CDS             8472..10118
                     /locus_tag="IXR05_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4260217.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLIFEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10109..11191
                     /gene="uxuA"
                     /locus_tag="IXR05_001719"
     CDS             10109..11191
                     /gene="uxuA"
                     /locus_tag="IXR05_001719"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4260218.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11299..12852)
                     /locus_tag="IXR05_001720"
                     /pseudo
     CDS             complement(11299..12852)
                     /locus_tag="IXR05_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            13000..14141
                     /locus_tag="IXR05_001721"
                     /pseudo
     CDS             13000..14141
                     /locus_tag="IXR05_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(14267..15346)
                     /locus_tag="IXR05_001722"
     CDS             complement(14267..15346)
                     /locus_tag="IXR05_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4260219.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15449..15889)
                     /locus_tag="IXR05_001723"
     CDS             complement(15449..15889)
                     /locus_tag="IXR05_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4260220.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(15946..16356)
                     /locus_tag="IXR05_001724"
     CDS             complement(15946..16356)
                     /locus_tag="IXR05_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4260221.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16536..16970)
                     /locus_tag="IXR05_001725"
     CDS             complement(16536..16970)
                     /locus_tag="IXR05_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4260222.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(17070..17918)
                     /locus_tag="IXR05_001726"
     CDS             complement(17070..17918)
                     /locus_tag="IXR05_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4260223.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         6173 a         3342 c         3236 g         5243 t
ORIGIN      
        1 attatctatt ttgttactgc ttacattagt agttggctat ttttcgattg agtttatcca
       61 tggattttcg tctgcaaaac agagttcaac tgtgaaaaag gtagagccga aaagtatccc
      121 taccacacta aatgtggctt tgattggttc agatgctcgt tcgaaagacg aaaacggtcg
      181 ctcggattca cttctgcttg cacaatacaa ccagaaaaca caataagcaa aactgatctc
      241 tatcatgaga gattcatatg tcgatattcc aggttacgga atgaataaga taaatgcagc
      301 ttactcttat gggggagttg atttattaaa tcaaacatta aaggaaaatt tcaaatttga
      361 agctccctat tatgcaagta tcacatttca agattttatc gattgcgtta atgaactgtt
      421 tcctggtgga gtcaagatcg atgcagaaaa atctctagat ttagatggcg tatatataaa
      481 caaaggagag caagtgatgg atggtaatac tttactccag tatgctcgat ttcgggaaga
      541 caaagaagga gacttcggga ggatcagaag gcagcagcaa gtgatcaaag ctatctctca
      601 gcagctgaaa gacgtaactt caatattcaa gctacccaaa gcggttggga aattacttgg
      661 tagtatccaa acgaaccttc cagaaagtgt gcttctggat tgtggtatgg atttcctcaa
      721 agacatatgt tagaataaac aggtataaat agtgaaataa aggaatgaca agcaagagaa
      781 ggaggaaaaa atgaaaagaa gtgacaagca cggcaaaaat cgaacaggcg cttatattgc
      841 cggcgcagtg atcttaatag cagctgcggg tggcggttat ttttactacc agcactatca
      901 agaaacccaa gcagtagaag ctggagaaaa gacagttgag caatttgtcc aagctttgaa
      961 caagggagat tataacaaag ctgcagaaat gacatcaaaa aaggcggcaa ataaaagtgc
     1021 attatctgaa aaagagatct tagataaata ccagaatata tacggtgctg ctgatgtcaa
     1081 aggacttcag atatcgaatc taaaagtaga taaaaaagac gattctactt acagtttttc
     1141 atataaagca aagatgaata cctcattagg tgaattgaaa gatctttctt ataaaggaac
     1201 attagacaga aatgatggtc aaaccacgat caactggcaa cccaacttgg tttttccaga
     1261 aatggaagga aatgacaaag taagcctgac cacacaagaa gcagcaagag ggaatattat
     1321 agatcgaaat ggtgaaccat tagcaacaac aggcaaacta aaacaattag gagtcgttcc
     1381 aagtaaactt ggagatggag gcgaaaaaac agccaatatc aaagcgattg cttcctcctt
     1441 cgacttaaca gaagatgcta tcaatcaggc gatttcacaa agctgggtac aacccgatta
     1501 ctttgtccca ttgaaaatca ttgatggagc aacgccagaa cttccagctg gagctaccat
     1561 tcaagaagta gacggcagat attatccttt gggtgaagca gctgctcagc tgattggtta
     1621 cgtgggagat atcacagcag aagatattga taagaatcca gaattaagca gtaatggaaa
     1681 aatcggtcgc tcaggtttgg agatggcttt tgataaggat cttcgtggga caacaggtgg
     1741 gaaattaagc attacagatg cagacggtgt agagaaaaaa gttctgatcg aacatgaagt
     1801 tcaaaatggc aaagatatca aattgacaat cgatgcgaag gcacaaaaaa cagcttttga
     1861 cagtctagga ggaaaagctg gatcaactgt tgcgacaacg ccaaaaaccg gtgatcttct
     1921 tgcgcttgct agctctccaa gctatgatcc aaacaaaatg acaaacggga tctcacaaga
     1981 agattacaaa gcttatgaag aaaatcctga acatccattc atcagccgat ttgcgacagg
     2041 ttatgctcct ggatctacgt ttaaaatgat tacagcagca atcggtctcg acaacggcac
     2101 tatcgatcca aatgaagtgt tgacgatcaa cgggcttaaa tggcaaaaag acagttcttg
     2161 gggatcttat caagcaacgc gtgtcagtag tgatgtatca caagtagact taaaaactgc
     2221 tttgatctat tccgataata tatatgcggc acaagaaacg ttgaaaatgg gtgagaaaaa
     2281 atttcgtaca ggcttagata aattcatttt tggtgaagac cttgatttgc caattagtat
     2341 gaatccagca caaatttcta atgaagatag ctttaactca gatatcttgc tagctgatac
     2401 tggatatgga cagggcgaac ttctaattaa tcctatccag caagcagcaa tgtattctgt
     2461 ttttaccaac aatggcacac ttgtctatcc taaattgatt gcagataaag agacaaaaga
     2521 taagaagaat gtcatcagcg aaacagcagt acaaacgatc gtgccagatc tgagagaagt
     2581 tgtgcaagat gtaaatggta cagcacattc tctttctgct ttagggattc cgttggcagc
     2641 gaaaactggt acagcggaaa tcaaagaaaa acaggatgta aaggggcaag agaacagttt
     2701 cttgtttgct ttcaatcttg ataaccaagg ttatatgatg gtcagcatgt tggaaaataa
     2761 agaagatgat gattcagcaa ccaaacgagc atcggaacta ttgcaatacc tcaaccaaaa
     2821 ttatcaataa aaaattgctt tttaagtaca gtaaaaggac tgtggcgtta tcgtcacagt
     2881 ccttttttca aataaacggt tttcacgatg tctctttcac aacttctttt tgatttactc
     2941 acacttcata aacttttttt gtaaaatatt tgagaacaag tggagaaata agtgtactta
     3001 ataaaatcac gataactaaa ggtgaatagt actgtggttc gatcaattga ctttgctgtc
     3061 caatttgtaa aatgatcaaa gccatttctc cacgcgaaat cataccagca ccgaccatca
     3121 atgaactatg ttgagaaaaa ccggcaatct gagcaccaaa ataacctcca agcaatttgg
     3181 tcaaaatcgc tacaagcgtc aatatagaaa taaagagtag ttgttcacta aagtcagaaa
     3241 aatcaacttc taatcctaca ctgacaaaaa atactggtat aaatactgca tatcctaaag
     3301 cctctacatt gtggtatact tcttctttaa cctttgtctg actgacagct atcccagcaa
     3361 aaaaagcacc aatgacagag ctaagcccaa caagatccgc tacgtaagac attcctaaac
     3421 aaataactag cgatacgatg ataatagaag aatttgcgta cactttttct gcaaatgaaa
     3481 gtaggaaagg cgcaatccat ttgactaata agaaaataaa aacaaaataa attagctgtt
     3541 caatcaaaac aagcggtaaa gaagcattgc tagaagcttc ccccgttaga aaagataggc
     3601 tgaaacttag aactaaaacg actaaaatgt catctaccac agaagcaccc aaaattgttg
     3661 atccttcttt tgtattcact acgtttagtt cttttaatac ttctactgaa atactgacag
     3721 aagttgccgc aagaataatc ccaaagaaaa tcgcttcatt tcccgaaact tggaatgctt
     3781 tgcctgtcaa ccagccaaaa acaaccggga agatgatccc aagcaaagca acgaacatac
     3841 caggtcggaa atattttttc aaaagagata aatcactttc cagaccagct aaaaacatta
     3901 ataagatcac accaatctcc gaaaagtcat ggactagaat atcaggtttg acccaattca
     3961 atccagcttg gcctagcaaa acaccaacaa gtaattgtcc aatcactgct gggataccta
     4021 atctccgcga gatatgtgag ccaatcgttg ttgaaatcaa tatcaggcat aaaataccaa
     4081 taaattccat tctcatcatt cctttgtata aaatatagcc cgaacttagc ataacataca
     4141 ttattgaaaa aataggaaaa tatactcaca aaaaaaccaa caatccaaaa gatttttttg
     4201 gattgttggt ttttatacgg tctattttaa taactaaaaa tgattaacgt atagtcattt
     4261 ttcttattct gatgaaattg ataatctcct ggatgcccat gaaaatcaaa ataaagccga
     4321 atatttggaa tagaagcatc aaacttttga atggattgaa caataagacg aatccgccaa
     4381 tcaacaacag aatactacta taaacactcc aacttttagc ttttgtattc atgctgaaga
     4441 acaactggaa caagctgttg atgataacag ctaatccaag aagaatcggc aggatagaaa
     4501 cgattgcagg tgcaaaagca tagacgatca gagctaagat caggaaaaaa agaccactga
     4561 acagaccgat actccaagaa cctgttttcc ttttaaaacg gtaagcctca aaaagattca
     4621 acaacccaag caaaacaaga taggcggtga tcagataacc gataaaatga aaaacagcag
     4681 aagggtttag cacaatcgca atcccagaaa taatataaac agcagctctt aataaggcgt
     4741 atttttgaat attttgttta atcgtctcaa acatataaga aaacctcctt tgacttattt
     4801 taacgtgaac tagtcatttt accaaattaa atgttacaaa atgagcgaag gagaagaata
     4861 tctctggaaa aatcaacttc tgaggatctt ttccattttt ttgccttttg ctagctcatc
     4921 gatcatttta tctaaataac gaatttcttt catcaagtta tcctcgatgt cttctactcg
     4981 tacaccacaa acaacacctg taatcaagga acgtgaagga ttggggacag gggcttccgc
     5041 aaaaaattgt tcgaaagtca cttgtttttg tagttgatat tctagttctg tttgggaata
     5101 acccgtcagc caacaaatga tttcatctac ttcctctttt atacgatctt ttctctccgc
     5161 ttttgctaca tacataggat aaacgcttgc aaaacttgtc gtaaaaatac gattttgcgc
     5221 cataatcagt cacctttctt tttttcaaat tatttactac ttatagtata taagaaaaag
     5281 agaagaaaaa gcgattattc aaaaaaacaa aaaggattgt gacaaaattc ttgtcaccat
     5341 ccttttttcc gctctctgac tttttacaat cttcatagct caagtgcgca tcagataatc
     5401 gaatgctcct aaagctgcag tagctcctga acccattgaa acaatgattt gtttgtatgg
     5461 actatctgta caatcaccag ctgcgaaaac gccggggata ttcgttgcgc catttttctc
     5521 ggtcactatt tcatttcttg gattcatttc gatcgttcca tctagccaat ccgtattagg
     5581 gagtaagccg actagaatga atactcctga aacagctagt gtatgcatct ccatcgtacg
     5641 gcgatcgata taggagagag attctacctg attcgtaccg ctgatttctt tcgtcgctgc
     5701 atgtttgata acagtgacat tcgcaagaga gactagttta tcctgtaaga tttgatctgc
     5761 ttttaattct ggtaagaatt ctagaacata tacatgtttt gctaacccag ccaaatcgat
     5821 tgctgcttca acaccagaat taccaccacc gataacagca atctcttttc ctttaaataa
     5881 agggccgtca cagtgtgggc aataagcaat tcctttattt ttaaactctt tttcgcctgg
     5941 tacattgata gaacgccagt gcgcacctgt cgcgatgatg gcggtttttg ctttaagtga
     6001 tataccgtta gctaagccaa tattaataaa atgttgctct ttatttaagg aaacggcctg
     6061 ttgattcatc ataatgtcga tagggtaact acgcacatga ctttctactt gctgcatcaa
     6121 ttttggacct tctgtgtaag aggtaccaat catattttca atccctagtg tttcaacgac
     6181 ttgtccgccg aaagaatcag cgacaagtcc tgtacggatt cctttacgtg ctgcatagat
     6241 agctgcacta ctagctgctg gtccaccgcc aatcactaat acatcataag gttctttttc
     6301 aaacaactct tcttcaatca aagggccagt gattttttca acaatttgtt cgatcgtcat
     6361 gcgtccgcta ctaaattctt ctccatttaa aaacacagtt ggcactgcca tgattttttt
     6421 atcatcgatt tctttttgga acatcccacc ttcaatcatc gtatgagtaa tatttggatt
     6481 taatacagct aatatattca atgcctgtac aacgtcgggg caattatgac aagtcaagct
     6541 aacataactg tcaaaatgca atgtttgtgt tatttttttg attttaagac tcaaagattc
     6601 actgattttc ggtgcccgtc cactaatttg taacatagcc agtaaaaaag aggaaaattc
     6661 atgaccgagg gggataccag caaaaacgat tccactttct ttgccaactg gattgataga
     6721 aaaactaggt gtgcgcatcg aatctctttt ttcccaagag attttaggag acatttctgc
     6781 tatttccttc gtaaattcag ctagtttttg actattttca ctattatcca aactaacaga
     6841 aaaaacaata ggagattcaa tcagtgctaa atattgttcg agattttgtt tagtttcttt
     6901 gtctaacata tccaccacct aaatctttcc aacaagatca aaacttggtt tcaatgtttc
     6961 gccactttct ttccattttg ccggacaaac ttcacctggg tgggtacgta catattgagc
     7021 agcgcgaatc ttatcaatca gtgcactagc gtcacgaccg attccatctg cattgatttc
     7081 catagcttga acgattccgt ctggatcaat aataaatgtt cctcgctgag ctaatccttg
     7141 ctcttcatcc aaaacatcaa aaatacgaga aatctgatga gacggatcac cgatcatcac
     7201 gtattcgatt ttaccgatag catctgatgt atcatgccat gctttgtgag taaagtgggt
     7261 atcggtagag caagaaaaga cttcaacacc taaagatttc aatgtactgt attgttcttg
     7321 taagtcttct aattcagtag gacaaacaaa agtaaaatca gctggataga agcaaagaat
     7381 actccagttc cccataagat ctttttcact gacttctaaa aattctcctt gatgataagc
     7441 atgtgcatta aattcttcga tttttttccc aatcaatgac atagtaaaac ctccaataat
     7501 aattatttat ttataattat tgtaatttag ttggagttgc aaagtcaatg gatattttgt
     7561 tatttaataa agattactca aaaacgaagg ttaattataa aaatagaaga ggtcgcaaga
     7621 aaatgctact gctggaaata ctcgggataa cgttgagtaa cagtttcctg ttctttcagc
     7681 atcatgtgta agtgcaatcc cgtttgaaat cgagcttctt ctggtttttt atcaactaaa
     7741 gccttgagta aatcataatg ttgttccatg atcgtttccc atggaagccc ctgaatggtc
     7801 actcgtaacc agcggaaacg ttctaaatgg gtattatggt catctaacca gttccaaact
     7861 tcttttcttc ctgcaatttc gaaacaagct tcatgaaata aattatctgc acggaaaaaa
     7921 gcgcgttcgt catttatttt gactgctttt tcttgttctt ctaaaatcgt ttctagcact
     7981 attcgtgttt gtgtgtccaa tttggaacaa cattcaatca tgatttgctc ttccaactgt
     8041 tctcggacaa agcgagcatt ttctgcagaa acaagattaa ttttggaaac atacgtacca
     8101 ctttgaggta tcgtatacac gagttcttgc tgacgtagtt gaatcaatgc ttcgcgaatg
     8161 ggagtccggc cgatagcaag atgttcctcc agtgcctttt cagatatttt ccttccaggt
     8221 tctaagtcag catagataat ttgtttacga atcgcttgat aagcttgtga ttgcaagctg
     8281 cttttcatct ttattcctcc aaaatcattt ctatgaacgt agtataacag aagaggtctg
     8341 aaaaacaatc tggtatgtca cattaactag taaatttgta taaatagtaa aattttggtt
     8401 gacatagcga tttttattgc ataaaattca cttgaataca aaaactaata tgttagttta
     8461 ggaggggaaa aatgattgat ttaaacaact ggaggaactt tatccctgaa ttatctcaaa
     8521 aagaagtaga aatacctcat tttgaccgtg catcattaag agaaaatgga caaaaaaatc
     8581 ctgtctggat ccatttcggt ggcggaaatc tttatcgagg atttcatgca gaaatcgctc
     8641 aacgtttagc ggatctaggc gaattgtcca ctggtgtcat tgtttgtgaa acattcgatg
     8701 aagaaataat tgaaagggct taccaagatt ttgatgattt gatttttgaa gtggtcatgc
     8761 caagcagtgg agagttcgtc aaacgtatat tagctgcgac agctgacagt ctgtattgtc
     8821 atccagattg ttctgaacac tttgataaga tgattcgaca ctttgaaaat cctagtttac
     8881 aattagttac ttttgctatt actgaaaaag gttatcgatt gaaagataca aataataaat
     8941 atataggacc gattgcagtc gatataaaaa atggtccaaa gaagccatca catacaatga
     9001 gtattcttgc tgtgctactt tataaacgtt ttttatctgg agcttggccg attgcacttg
     9061 tctctacaga taatttttca caaaacggta gtcaattacg tacttctttg ctaacgatcg
     9121 caaaagaatg gcaaaaggaa ggttatgtac aaaatacatt tatccaatac ttatcgaatg
     9181 aagaaattgt tgcgtttcca tggacgatga ttgatcgtat caccccgaat ccttccttgt
     9241 cagttagcaa aatgttggca aaagagggct tttcaaatat gtcgattttc caaaccgcaa
     9301 aaggaaataa tattgctcca tttgtcaata cagaggacat ccattattta atcatggaag
     9361 atcattttcc caatggacgt ccgaaattcg aaaaagctgg ggtattcttg actgatcgtg
     9421 caacggtaga taaagcagat acgatgaagg tgacgacttg ccttaatcct ttgcatacgt
     9481 ctttagctat tatgggttgt ttactggggt ataggagcat agctgaggag atgaaagatc
     9541 cagatttatc gctgctagtt tctgaaatcg ggtacaatga aggcctccca gttgtggagt
     9601 ctccaggtat cattgatcca aagatctttc tggaagaagt aattactgtg cgcttttcta
     9661 atccaaatat tcctaatatg cctcagcgaa tcgccacgga tacctctcaa aaggtggcga
     9721 ttcgttatgg tgagacgatt aaaaaatata tggaaataga agttaaagac ccgcagacac
     9781 ttgtattcat accattgact ctcgctgctt ggcttcgata ccttattggc attgatgatc
     9841 aaggaaaacc attcatcccg agtccagacc cactattgac agaccttcag cataagcttt
     9901 ccgatattca actgggtacg caagatacat cacatattca tgagaaaatg gctcctattt
     9961 tgtcaaataa agaaattttt ggtgtagatc tttaccaagc agagcttggc agaaaaatag
    10021 aagaaatgtt catcaagatg gtagcaggac caaatgccgt acgaaaaaca ttacaggatt
    10081 acttacaaga acatggagga aatttatcat ggaaatgact tttagatggt acggatcaca
    10141 ggaagaaaag attaccttag atgaaatcag acagattcct gcggtcaaag ggattgtagg
    10201 cacattgatg gatataccag taggagaggt atggcctagg gagaggatca aagaactaaa
    10261 agaagaaatt gagtctcgtg ggttaacact aaaagtaatt gaaagcgtca atgtgcatga
    10321 tgccattaaa attggattac cttcccgtga gcagtatatc gaaaactata agcagacaat
    10381 ccgaaacttg gcagaatatg gaatagaagt catctgctat aattttatgc ctgtatttga
    10441 ctgggtgaaa tctgaccttg actaccgctt agaagacggc tcatccacgt tagcttttat
    10501 atctgatgat attccagatg atccaagaga aatcgtcgcg cgcatcgaac attccagcaa
    10561 tgaatttgga ttgccgggat gggaacctga gcgcttagct cctatcaaat ccttgcttga
    10621 agcctatgca tcagtagacg aagaaaaact tcgagaaaat tttgcctatt ttctccaatc
    10681 aatcatccca acatgtgaag aggtaggggt caaaatggct gtacatccag atgatccgcc
    10741 atactcgatt tttggattag ctcgaatcgt aaagaatcga gaagatttag attggttgtg
    10801 tcgcatagta gacagccctt ataacggaat cactctttgt acagggagta ttgcagaaga
    10861 tccagaaaat gatgtatatg ggattttagc agaattttgc caaagagatc gaatcccatt
    10921 tgcacatgtt cgaaatatta aatttttagc taatcgagat ttctatgagg caccacataa
    10981 atccgaatac ggttcattag acatgtaccg catactaaaa acaatgtatg acaacggatt
    11041 taacggatac atccgtcctg atcatggaag aatgatctgg aatgagacag gaagaccagg
    11101 atacggctta tatgatcgag cattaggtgc tgtttatcta aatggattat gggaagcaat
    11161 cgaaaaagga aacaaaagta aagataatta gtgaaaaaaa ctgtaatttt attatgtaaa
    11221 taagaaggat gttcaaattc ttgatacata aatccggagg ttgttaataa gcattcggat
    11281 ttatgtatct tatttggtct aggaagtaac ttgattttct tttttcgatt gatccatgag
    11341 tgcttcttct tttaattcaa agatatattc tgagatcctc ataatcactt ttttccagtc
    11401 ttctggtgtg atgattcctt ttaaaatata gatttttttg atatgagaag gcaattgttt
    11461 caaagggcag tcgctgataa cgatgttgca gttctccata aaatcatttt gtattttgat
    11521 cgattcattt gaaaaaattt gttctatctt aacgatcaga tctttactga tataaaaatc
    11581 acgcgtatag ttcacaccaa tcacaattcg cggctgtttt ttgtagcgat catacaaatg
    11641 tactaggtct tcaaccatcc attgcacatt ttccttttct aaaataactg gtaacaagtg
    11701 ttgattttgt tctctgaaat ccatataaaa ttgttcaatg gcggtttgga cttctttcaa
    11761 tacgctatgt tcttgataaa gcatgaaagt aggaaggggc gtatttggtt gattgaagtt
    11821 aagaaatcca ttataaagtt tatttcgtgc gaatgccaat gagtaaagaa tcttttcttt
    11881 ttcaggtata aacaaatcaa atacagtaca aagggactcc accatttctc ttgaataaag
    11941 aacatgagga acgtttgctt tttttaaaag tttgtattgc tccaagcttg tttcttccga
    12001 ttcgattttc gtgatagaaa gtcgagctaa aatattcact aagatgcgtt gttcgcgaca
    12061 aattggcaga ttaggtcgca aaatatctac agagagatca ataaaaaagt caatatattc
    12121 atactctgtg aattcttttt gtacgtcttt cacagaagtt gcaggaaaat tctctttaca
    12181 tatttttaat agaaaatata atttatctat cataccgcta tttagtcggt caagtacttc
    12241 ttttttaaaa aaagtattca tcataaaagc cactacttgc ggatcttcat cataaaattc
    12301 tgtagcagta cttgaaaaga tgttccaata aatatctaat gctgcatatt gaatttgtac
    12361 ctcttttcca gaaaaagact ttctgccatt attagaaaag gagatagaca aaccgtacta
    12421 tgctaaaaat gcattaatct ttttcatttt cgtatacaaa taagaggcac tatagtttgt
    12481 ttgctgactg aaactgataa tcgaatttgt ctgacagctg aacaaagaag tcaagatctg
    12541 ataactgact gattcgttgc agtatcttcc aaatagacga taatagcagt aagccggatc
    12601 aattccttca aaattcaact ttaaaaaagg tttttgctta tcaatatgca gttctgttag
    12661 attgagacgc tcaaagtctt gttctaattc tttgatgtat agtaaaaaat ttgattcaga
    12721 catatggaaa tgatctgcta aatattgtgt agtaataaag aaacgatgtt cagataggaa
    12781 aagaaaaata tctaattttg tattgctttt tttcttcaag ataaacgttt taatcgcttc
    12841 ttgagtttgc atgaaagagg ctccttttta cttaaattgt taaaacttga aaatattact
    12901 gtttttttca taaatttaga caaaaaaaca gtaaacatat aggtagaatc tctactatct
    12961 tatttcttgc atacaaaaaa atcaaggagt gagagagtta tgagatattc aaccatctta
    13021 atatcaacat ttgcagcctt aagcttatcg cttactataa atcagacagt ccacacagag
    13081 gagacagaaa cagccaaatg gacagaaacc aagtgggcca acgtcaatcg aattaccttt
    13141 caggatgaat tttcatcctt caattcagga gtcgcaaaat taagaaaagg acaaacagcg
    13201 accatcaaag caaaaattga ctattcggga gacttagcac ctatactaca atcagctgtt
    13261 acatttgaga atgttgatcc cactttgtcg attggctatg acgagaacac tttgactatc
    13321 caacacaagc aagcgatatt taccttcacc gttacattaa atcaggactt gttaaaacca
    13381 gcgcttttta ctgtcaaggt atcagatgga ctaccgaacg atcatcattt aacgccgtat
    13441 agtcagcggc agacaattga gcaagattca gccatcgact caggaggaga tcttgttgaa
    13501 gaaccaacag ataaaccaga aaatgaaaat aagccagaag taccgcctac agaaaatcca
    13561 gacggagaac agaaaccgga aatagaacct ggagaagaac ccgatacaga aactcaacca
    13621 gagccagaca ataaatcaaa acctgaaata acccctggag aaaaaccaga tgtaactcca
    13681 gaaccagata cggattctgg aaaccaaaca gtaccggaaa caaatccaga cacagataat
    13741 gaaactgaaa atccagaaaa accagaggta gatccagaag aaaaaccaga tgtgactcca
    13801 gaaccagata cggacgcaag agaccaagga ataccagaaa aaataaacaa aaaaacaatt
    13861 caagaggatg gaaaaaaaga gagtaaaaaa tcaaatctag caattctaaa aataaatgaa
    13921 gagcagctga ataaaaaatc acgaatattt gatagcgccc aatcagctga aaccttaaaa
    13981 agtagcaagg atacaacctt tgctgtcctg aaacgaaaaa taaacagcta ccaaaatccg
    14041 gagagtcaca aaacaaagtt atactgtgga gcggaatcat tctattaagt atagcaacaa
    14101 tgctttctgc aaaaagattt aaacaaaaca gatctctcta acatttgaat aatgtctgtg
    14161 aacgcatttt tcaaataaaa agaaatatcc agaaaatgac cccaaaatac cagattgaaa
    14221 tctgatattt ggggtcgttc atactttatc tttcttcata tttattttaa gggatatctg
    14281 tttcttttgg aagatggttc gggatctttt tcactttcaa tacatctaaa aagaaggtaa
    14341 agatcggaat gccgacaatc aagccccaaa cgccaaagaa ccgttcgcta acaagtaaga
    14401 ccacaaatgt ataaaaaatc ggcagttctg ttttgctgga catcaacttc ggattcagca
    14461 cataagactc aattagatgg acaatcaaaa tcgtaatcag gatataaaca acatctcgga
    14521 tgcctccttg ggaataagct atgaaagata gaggaataca agaaatgata acacctgcta
    14581 ctgggatcag acttaaaatg aaaatcatga tcgctaaact cagcagctga tgaaagccaa
    14641 atacagccaa ggcgattgta gtgagcaacg tatttaaaag agcgacaaca aattgagctt
    14701 ctaataccaa accaaatgta ttgacaaact tatcggcaaa atagtaaata tcttgaaaga
    14761 accaagaaaa ttcacttttt aaaaacaatc ttgagaatac aattgttttt ttcttttcaa
    14821 tcataaaaaa gaaacttaag atgaatgaca tagcaaacgc cactgccatt tttcctatat
    14881 cctgtaaata gccaagcgca atcgaagcgc cattttgaag ctgttcaaaa aaatcgtttc
    14941 gctcaatata agtatggata tattgtaaaa caggatctgc atcttttggc tgatgctcgt
    15001 aaaaattaat aacggactgg atcatgtcaa atgtttgatg aataagcatc gggatatact
    15061 ttgtgaatgc cagatagata aggtaaacga tcagtgtata aatcatgata gctaaaacac
    15121 ctgtagggat tcggacaaat cgctgaatga tttgaacaag atgaatcatc aaataagtaa
    15181 agataaatgt gagcaaaatg gttgtaatca tacttctaac taagaaaaga acaaaaacga
    15241 caaataataa aacagtgaga cggcgtattt tttcattcgc caaaaaacgc tgataaacgg
    15301 tcaaatcgac aacctccaaa taacaaaaaa taaacacgtt attcattata tgatggaata
    15361 tgaaaataag aaagagcaaa aagaaaaacc gctaaatgac gttatcttat gagttggttt
    15421 tcctcataaa atcgttcatc tagcagtttc agcccttttt ctggtcttga tgaaaattat
    15481 ctagcatttt tcgggtcaga tgttgcagtg tatccaattc ttcctgttca agtggaagat
    15541 aagacttgat cttttgtgga ataccttctg cttgtttttg caacgcagca ccttgagcag
    15601 tcagcgtaac atttacgatt ctttcatcac ccgtttcacg ctgacgatta atataatttt
    15661 tttctgctaa cttttttagt aagggagtca gcgtaccaga atccagacac aaatcatttc
    15721 ctagctcttt cactgaagtc tttttctttt cccataaaac taacatcaca agatactggg
    15781 tataggtaag attcagcggc ttgaggaggg gagtgtagtg tctaatgatt tctttagagg
    15841 cggcatataa aggaaaacat acttgattaa ctaaatatag atcttccatt tttccacctc
    15901 cgctgtttta ctatagtgta tcatagcgga tttacacaaa aaagtctatt cactaactgc
    15961 tttcagagta acttctatat ttccagctgt agcttttgaa tacggacaca ctttatgcgc
    16021 tgcctctaat aattcttgcg tttcttccag agaaagacct tcgatagatc cttcaatctc
    16081 tacacctaag acaaagctcg tttcactttc tgaataaagg gaaacttgtg cactgacagt
    16141 agaagcccca gagatatttt tttgctgttt gatcaattct aatgcactgt taaaacatgc
    16201 actgaaacca gctgcaaaca attgttcagg gttggttgca ttttcgacgc gtttaccagg
    16261 agctgcaata ttcaattcga atgtacgatc gggattatgc acttctccag agcgtccgcc
    16321 tgtgttgatc attttcgtag aatacatttt tttcataaaa ttaccacctt taattatatt
    16381 ttatacaatt gaattttaca caatataatt gtggaaagca aagaaatgga ttggcataag
    16441 ataaataaga gaaagcacat gaaacagacg cgctttctcg aatagcaaac atatacaaaa
    16501 aatatcagag acaaaaaata atctcatcat aaacattaca tatatttctc aaaaagttgt
    16561 tttctttctt caaaaattac ttcacgatgg acctgatgaa gcatccataa ataaccaaaa
    16621 ggatctctga acattgagtt agtcacacca aagtccatca tttctgtcat ttcttgaatc
    16681 tctacacagc catttcgtaa tgctttatta tgtgtgtcct cgatatcaga gacgatgata
    16741 ttgaaccaga tcgtatttgg atgttcagca gtaggagcag tcaaaccaag agacgtgttt
    16801 tcatccagca tatggaatct cgtaccatac aaggtaaaaa tgacttcatt attgcctcta
    16861 gggtaatctg ttgcctcaat cagttgtatt tcatcaaaga ttgtttgata cagttctagt
    16921 gctttcaaac tatcatttaa tacaaaatcg atttccgttc ctttatgcat aaagatctcc
    16981 tctccttttc agtcgaacag ttactagatt cttttattat accagctaaa gaaaacgcat
    17041 tcaaaaaaat agcggattta cttaccaact cattcgattg gatgataagt aaatccgcgt
    17101 cccattactt ctgctacgct gctgacaatg acaaaggcac ttggatcgat ttcttctatc
    17161 aatggtttca ttcgggaaaa ttcatgatca gtcacaacga tcaataaaac ctcttttgac
    17221 tttcgattat acccgccttt tgcctctagc agggtaaggc cacgtccaat ctcagcactt
    17281 aagcgaaggc ggatgtcttc caaataatgt tcactcatga ccataacaga tttctttcga
    17341 ttgatacctg tttcgatata agtcatgaca attgaagtga ttgcaataga taaaatagca
    17401 taaagaaact cttctattcc aaaaataaac agattaagag aaacaacgaa tgcgtctgta
    17461 aaaaataagc caatcgaagt attcaagtgg aaatattttt taaaaatgag gggagggatc
    17521 gtcgtaccgc cgctagaaga gttgttttta tataaaatcg caactcctaa agcaaaaatc
    17581 gcacttccaa aaatgacaga caacaaccga tctgaagtaa tcattgtttc tggaactatt
    17641 gcaatgatta aaggaaaaac caagcttccg aaaagtactt taaaaaaggg ttttttacct
    17701 aaaaatagaa gagctagtac caacataacg atattcaaca ctaaaataac tatagctcgg
    17761 tcaaagccta aagcagcttc cagtaatatt cctagaccgc tgacacctcc agcagcaata
    17821 tgatgaggcc ctaaaaacat attgatagcg actcctaata tgaagagggc aaaaataatc
    17881 ttaatgtatg tccatataaa ttgtctcgtt tctttcattt attcacttcc ttaattcatt
    17941 aataatactc ttatcttatt ataacttact tttcacctta agttaacttt aatt
//
LOCUS       DACGDM010000047        17461 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.048, whole genome shotgun sequence.
ACCESSION   DACGDM010000047 DACGDM010000000
VERSION     DACGDM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.048"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            126..386
                     /locus_tag="IXR05_001727"
     CDS             126..386
                     /locus_tag="IXR05_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260224.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(748..987)
                     /locus_tag="IXR05_001728"
     CDS             complement(748..987)
                     /locus_tag="IXR05_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260225.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            1273..1587
                     /locus_tag="IXR05_001729"
     CDS             1273..1587
                     /locus_tag="IXR05_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260226.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            complement(2021..2387)
                     /gene="ssrA"
                     /locus_tag="IXR05_001730"
     tmRNA           complement(2021..2387)
                     /gene="ssrA"
                     /locus_tag="IXR05_001730"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2558..3331)
                     /locus_tag="IXR05_001731"
     CDS             complement(2558..3331)
                     /locus_tag="IXR05_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4260227.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            3475..3825
                     /locus_tag="IXR05_001732"
     CDS             3475..3825
                     /locus_tag="IXR05_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAQ4260228.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            3806..4522
                     /locus_tag="IXR05_001733"
     CDS             3806..4522
                     /locus_tag="IXR05_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260229.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            4522..5970
                     /locus_tag="IXR05_001734"
     CDS             4522..5970
                     /locus_tag="IXR05_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4260230.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(6040..6549)
                     /locus_tag="IXR05_001735"
     CDS             complement(6040..6549)
                     /locus_tag="IXR05_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260231.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(6539..7264)
                     /locus_tag="IXR05_001736"
     CDS             complement(6539..7264)
                     /locus_tag="IXR05_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260232.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(7487..9607)
                     /locus_tag="IXR05_001737"
     CDS             complement(7487..9607)
                     /locus_tag="IXR05_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4260233.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            9837..11015
                     /locus_tag="IXR05_001738"
     CDS             9837..11015
                     /locus_tag="IXR05_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAQ4260234.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            11031..11789
                     /gene="aroD"
                     /locus_tag="IXR05_001739"
     CDS             11031..11789
                     /gene="aroD"
                     /locus_tag="IXR05_001739"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAQ4260235.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            11812..12297
                     /gene="ybaK"
                     /locus_tag="IXR05_001740"
     CDS             11812..12297
                     /gene="ybaK"
                     /locus_tag="IXR05_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAQ4260236.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(12368..13621)
                     /locus_tag="IXR05_001741"
     CDS             complement(12368..13621)
                     /locus_tag="IXR05_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4260237.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            13739..15088
                     /gene="gdhA"
                     /locus_tag="IXR05_001742"
     CDS             13739..15088
                     /gene="gdhA"
                     /locus_tag="IXR05_001742"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAQ4260238.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            15200..16546
                     /locus_tag="IXR05_001743"
     CDS             15200..16546
                     /locus_tag="IXR05_001743"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAQ4260239.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(16854..17240)
                     /locus_tag="IXR05_001744"
     CDS             complement(16854..17240)
                     /locus_tag="IXR05_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4260240.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(17289..>17461)
                     /locus_tag="IXR05_001745"
     CDS             complement(17289..>17461)
                     /locus_tag="IXR05_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAQ4260241.1"
                     /translation="VETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQR
                     RFEGTLRYSLGY"
BASE COUNT         5730 a         3043 c         3462 g         5226 t
ORIGIN      
        1 tggtcatttc tgtttttcgg tttttttatt tttttataaa atcacaagtg ttattgattt
       61 tcacaatcat attttaatgg tattatcatt ttgaataatg aaaaaacatt aaggatggat
      121 gaaatatgaa taacgaaact atcattttag gaaaaaaata tatttgccaa cctattggct
      181 tgaaacaaaa agtggttgga gaagtaatca gtaaattaga aaattgtgtt gtgatctgcg
      241 tagacgaata tcatgacgtc gatcgcaatg aaatattaga aaaatgcgga aaagtagtgg
      301 caaaatatac tcacgtttat gagttggaaa caacagaata tctatataac tatagcaaca
      361 aatatgaaca tactttagtt tcataaagat ttaaataaag tgccttcaaa agcgagaaga
      421 ccaagctttt gaaggcactt tatttagttg gcagtgattg ttcatgattt ttgatttatt
      481 caaaaggttc gcctagagaa tctgtctctg taacgaggcc tggtggagaa actcgataaa
      541 aacctatact gccagaactg tcctattttc ggatagacaa actagtagtt ttaaaaagat
      601 catccgatcc aatcatttca aaaaatgcaa aactgatatc aggatcattt agctcaggct
      661 tgttatcgta aagcatttgt aaaggttgca tttagttagg agtaaacgcg aaactatcat
      721 cattatttgc tgaagaagat gaagaagcta attcagagtt tgtttgaaat aaaggagacg
      781 tgctgacagt ttctttaccc tgttttttgc agaggtagaa acttttatat cggaagtttc
      841 taccggagaa tttttctcat ttgtagaaat tgttgaatcg atactattcg aaatttgcgt
      901 atctgaaggt atgttctttg atgcagaagt cccacaagca gtaagtaaca ataaatttga
      961 taaactgata aacagaattc ttttcattat gtacacactc cttatagtat cgtttagcat
     1021 acacctatgc tcagtattag gcaaaatcaa tgcaaaacta tcaagtcttt tatagtatct
     1081 attagtctta gtaatacata tatggagagg gtgatatccc agttcaaacc agatacattg
     1141 gttaccatct gtattaacga ttatgcctct aaacgctttt tttatgaaaa aatttataag
     1201 tgaaaacgta ggtatgatat tatctagagg taattttttt gggtatttaa atagttgcta
     1261 ggaggatagc ttttggattt ttacagtaat tttatcttaa taatagcaat attattactt
     1321 ctaaatattt ggttttttga taagagtaga aatgcaggga taggttttag aaccaaacga
     1381 agtacgtctt ctgaaaaaaa gtgggtatat tcacagacta ttttttacgg aggggttatt
     1441 tcaatcagtt tactttcttc aacactttat tcttttaatg ttatagacgt ttccatgtca
     1501 aattttatat ctattattgg aatccttatt tctgcaatta ttacacaact acttcttgtg
     1561 tttgaagaga agtcaaaaaa taattaaagc aattatgcct tttagtacag gaattattac
     1621 ttcttacaaa tgtatagcga atgtgaagcc tgctgtttta attgttctag aaaaactttt
     1681 gagtgaacaa ttattttatg ttaggatgaa ttaatttctc tagagtttat aattaaaaaa
     1741 cttatttgaa ggaacatgct taaaccataa ttgtgttttt ccttccatca gcataaaagt
     1801 tcacctcaaa aagagtgtac gaacaaaagt tctttttgta aaccttaaaa tagattttcc
     1861 tgaatacgta ttggggattt ctaaatgttt gaatgttttt ttgaatgcaa aatcaatgca
     1921 aaaaattttg tatttctcta cttttctctc cttgaccaaa ataaaaaaac gttgatttaa
     1981 caacgttttt catacatgtt tatctgtctc aaccatacat atatggagac ggcgggagtc
     2041 gaacccgcgt ccaaacacat cgccacttaa aaatctacgt tcatagtcaa ctcatttaag
     2101 gattcacttt acagcttgcc gagtgacagg cattctgtat cgctagtctg atgttctctt
     2161 tttcaactta cagacggaaa gttgaaacgt atcccactaa agttaggacc cttactcgag
     2221 cacatgggcg atgccgagag gatctacgct aactgttttt aggcagctaa agcgtaagag
     2281 ttgttttcgt ttttagcagt tatatttaac tgtaacgttt ttacgtagac gtaacctacg
     2341 aaacgcaatt caagctcgac tgtgcctgtc gaatccgtaa cgtccccgtt agctaacaag
     2401 ggttacgtgt atttttcata caaaattagt atagcatata ttgggataaa ttcaataaaa
     2461 aagcgaatca tatcccatta tttatataat aactgcccct ttcttaagaa aaaataagcg
     2521 attttcttaa gaaaagaggt agcttcaaaa aaagatctta aatcagatca aaatacttca
     2581 atgcgtggac aattccgcct tctgtatttt tctttgtgat aaaggtagaa agttctttta
     2641 atccgtcata ggcgttgccc atagcgattt tgttgtcgca agcttccaac aaggcaaaat
     2701 cattcggacc atcgccaaat ccaaaagtag gaactttttc cagctgaagt tctttttgca
     2761 gacgtttgac acctgcccct tttgagattc ctttcttcac tgtatcgatc gagtaaggac
     2821 cattccgata aaaagttagc tcaggaaaat gttcgtgata gtattcgtca cctgattgag
     2881 ataagatcag caacatattt actgtgtttt ctttaaagcc taaaggatca atttccggaa
     2941 catctgaatg aatgaagtcg taagcattga tcattgtttg gctatgaccg gtacaccaga
     3001 ttttctgatc gttatagtaa gaaagttcat gaccgttcaa ctgtacatga tcatacattt
     3061 tttgacattc ttctgaagaa aatgtttgag aatagatttc ttcgccgtct actcgaatga
     3121 aagaaccatt catggtgacc gcagaagtaa tgcccgcatc ttccatgata gagtggattt
     3181 ctgcttctgt acgtcctgta gcgatgacgg ggagaacatt gttttctttt aatgcgttca
     3241 tagcttttgc cacttcgggt gtgatttttg atttcgcatc tagtaatgtt ccatcaagat
     3301 caaagaaagt gattgcacga taatttgaca caaataaaac tcctttttta ttggaataag
     3361 tttatcttaa caaagaatga acaaaagaca aacctttcgt gaagaattcc tgaacatatt
     3421 ggttcagtca acaatttaga gtatactata agaagagaat ttaggaggga aagaatgatt
     3481 tttttcagta ttggtatctt attcttaata attggcagtc tttttcggat tctgccctca
     3541 aaaggaaatc tgccttttta tgggtatcat tcgcctcttg ccgcaaaaac agacgctcat
     3601 tggcggctgg ctcaaaagac aagcggaaac tggttttttc ttatgggctt actgatggca
     3661 ttgatcggct attatttaaa gacatctggg catacgaatt attttctgat tgaaatgctt
     3721 ctgctagtat ttccaattat gcctattttt attatgacag aaaagaaatt acagaaatat
     3781 gacctggaaa ctggagggaa cgataatgaa tattttaatg attgaagata atcaatctgt
     3841 ttctgaaatg atgcagatgt ttttcttaaa tgaaggttgg gaagcaactt tcaagtatga
     3901 tggaaaagaa gggctcgatg cctttttaga aaacccacaa cattgggata tgattacact
     3961 agacctgaat ttgcccacac tggacggtat gctagtagga agagagatcc gcaaagtttc
     4021 aagtactgtg ccgattatca tgctgacagc tagagattct gaaagcgatc aggtgatcgg
     4081 cttagagatg ggggcagatg attatgtcac aaaacctttc agtcctctga cgcttattgc
     4141 tcgaatgaaa gctttgcatc gccgtagtga gttggcagaa gcaagagaag aagcagcagt
     4201 ttcagatgat cattttgata tcgagactag tcatttcaag atgaatacga aaacacgaga
     4261 agcgtatctg gacaaccggc caattgaagg actgacgcct aaagagttcg atctattgtt
     4321 tactttagca aaaaaaccac gtcaagtatt ctctcgggag cagttgcttg aattagtctg
     4381 ggattatcag tactttggtg atgaacggac agtggacgcc catatcaaga aattacgaca
     4441 aaaaatcgaa aaggtcggac cacaagtcat ccaaactgtt tggggagtcg gctacaaatt
     4501 cgatgattct ggtgttgcct aatgcgttat ttgtatcagc aactcttagc tttttgcgga
     4561 atggtcgcgt tgatcttatt gatcgttgga gtttctttta cacaactgac aaaacaaacg
     4621 attgaagaaa acaattacca gcaactgttt ggatatgctg aatcagttga aaagacaacg
     4681 caaacctatg ccgatacgct cccgcagttt agtcaagatc aggcgtttca aaatgcattg
     4741 ctgctgacag agcaagtact gacagaacaa aatgtgaact ttatatttat cgataaaaac
     4801 gaacgtgtca tttatccgac taatacagct ttactgaatt ttaccttaac agctgatcaa
     4861 tggaaaaatc tgaggaatgg acgtcaagaa aaattcacat cgaataaaaa tattttagga
     4921 caagcacagg cgacctctta cgcacttgtg ccatttaatt tgaatcatga attctatgga
     4981 gcacttgtag ttagtcaacc tgcgcgaaat atcgataaca gcgttcgtcc aattacactg
     5041 aacctgttca aaggatttat tttttccagt atcgttgcag ttattgccag ctatgctttt
     5101 gcagcattcc aagttaagcg tatcaatcgg ttaaggaatg cgacgaaaga agtgacgaat
     5161 ggtaattttg atgtacagct ccccgtacat gacaaagatg aatttgatga gttagcagat
     5221 gatttcaata aaatgacgaa ttcattgaaa gaatctcaag cagaaattga agaacaagaa
     5281 aatcgtcgaa gacaatttat ggcagatgct tctcacgaga tgagaacacc tcttacgaca
     5341 atcaacggac ttctggaagg gttagaatac aatgcaatcc ctgaaaatca gcgagaaaac
     5401 gcgattaaat tgatgaaaaa tgaaacagag cgtctgatcc gtttggtgaa tgaaaacttg
     5461 gattatgaaa aaatccgtac gaatcaaatc agtatggtca ttaaaaaatt caatggaaca
     5521 gaaacattga aaaatattgt tgcacagtta gaagctaaag cagaagcagc aggagataca
     5581 ttgacattga aagccgttga tgatattgat gtttacgctg attatgaccg atttgtccaa
     5641 atcatggtca atattattca aaacgcgata cagtttactg aaaacggcca aatcacgatt
     5701 actttagaaa aaggctatct tgaaacgatc atcacgattg aagatacggg aattggaatg
     5761 tctgaacaac aaatgaaaag tatctgggat cgttattata aagtagatcc ttcaagaaaa
     5821 aatacaaaat atggtgaatc aggattaggt ttaccaatcg tgcagcaact tgtacgcttg
     5881 cataaaggaa aattagaagt agaaagcgaa ctaggaaaag gaacaaaatt cgctgttcgt
     5941 ttgcctgacg tagaaatcaa aaaagagtaa aaaacaagcg gtataaaaga tcatgaatcg
     6001 atcttctata ccgcttgttt ttactataaa atgattgatt tagcccgcgg gctctaaacg
     6061 atcaatataa ggactttgag caatagtagc atcatgagta aagagtaaga taccttgatt
     6121 ttcttcatga gctaaataag aaagcaagtg gagtagctct tggatctcca atacactaag
     6181 ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg gaaagcaagg catgaagtaa
     6241 ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc gcacaattaa gcaaggaagg
     6301 agagatatca agtttttctt gataggccaa acgatcttgt ttgatttctt tttccggtac
     6361 atccaacagg acatggtctt taagattcag ataaggaaac atcggccaat ttttttggat
     6421 gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt ttcaagtgct ccaatatttt
     6481 atgctgtttt tcgagaggac acaaaataac ggtcaagtgt tcagcatgaa tcaaatattc
     6541 aggtttcatt acgtccaggc ctcctacttt gcaaatgatg gataaaaaaa gtgaaaggga
     6601 atagactaag aatgagacag catccactga gcccaataag agtttgggca aatcccttaa
     6661 gtatatctgt gaaaaaaaga tcattttgga aatcgatggt aaaaaaagtc tgttgatcca
     6721 tcggaattgt aagtccgctt accgaagtca agatatcacg gatatctggc agttcagtag
     6781 tctttaagac aagaaaattg atcctttgaa gaagcgcttc ataaactgac tggaagctta
     6841 cgatccacaa taaaaccaag atacaacaaa gaaagagagg aaagaacagc tgccagaaaa
     6901 taaaaaggaa taatttggtt ttagaaagac cagtcaggcg ccaattgatc aattcctgct
     6961 tgttttgcct gactgaatag taaaagaaaa agataaaaag gaaggcaaat agaaaaaata
     7021 aactgaatat gccttttata taaaatcggc tagctaattc taaagccgga agaagctctg
     7081 tagatgcaga agcgccaata aatgaaagcc gatcttggac ttgattggct aaagccgatt
     7141 gcaaatggta aagagtcagg catgctatca ataaaaaagc agaaaagctt gaaaataaac
     7201 aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc agtagcatag cggattattt
     7261 tcatactttt cacctctata aaaagtatag aaaatgaata tgaataaagt atgaaattcc
     7321 tttagtgaaa tcacgaatta aaaccagaaa atattttgta aaaagcaaga ggttgtgaag
     7381 aagctgccct attctattac cgtagatgca agcttttgaa cactgtttat tcgaaaagag
     7441 gagcagcgac aataattttg tcgctgctcc ttttaaattt attttgtcat tcggaagaac
     7501 ttgtggtcgt tccgtgaagt tcttggtacg tttgcgtttt ataaagatca acagttgatt
     7561 gtccgttgtg ttcactaaag acactagttg acttgtcacc aagagatttt tcagcttctt
     7621 ttaatttctc taagccattc ttgtagtcat aatcactggt atcaattggg tctaatccac
     7681 tattcgtata gaaccgaaga agatcaccat tattgatttg gtcagaaaca gctaactgtt
     7741 tatcaacttt ttctttcagt gaatcaattt cattctgtac ttcctcagta ggttcagtaa
     7801 tagcttcacc agtttcgtta ctatagatcg taccaccgta gtaagtatat tttggtgtaa
     7861 caaaatcacc atcacggaaa gaaacaagct gttcatgatc tttcgagaat agatcttgtc
     7921 ctaactgaat ataatttttt gtatctacac ctagtaagtg aagtaatgta ggcaaggcat
     7981 caacttgtcc gccgtaagtg tgattgattc cgccctgtgt ttgtccaggg atatggatca
     8041 tataagggac acgctgcatt tgtgcattgt cgtagtttgt ccaagtagaa cttgtttttc
     8101 caactaattc agctagattt ttatttcttg aattcgagac accgtaatgg tcaccgtaaa
     8161 ggacgatgac tgaattatca tacaagccgc tttctttcaa ataattgaag aattcttgta
     8221 cggcggtatc taaataattg gctgtcgcaa agtaaccgtt gatcgtttca tcatttgtat
     8281 tggctaacgg gaatcctgct tcgtcattgg tgaattttga ataaggataa tggttagata
     8341 cagcaatgaa ttttgaataa aatggttgtt gcagacgttc caagtattgt acggattgtt
     8401 ggaaaaatgg tttatcatgc aacccgtatt ggaacgaatt gtcatcatta acatcataat
     8461 aagaagaatc aaagaaataa tcatatccta aattcttgta tgtctcgttt cgattccaga
     8521 atgtaccagc gttcccatgg aataccgcac tagtgtaacc ttgtgtttga cttaaaatat
     8581 caggtgcagc ttggaaagta ttttttccgc ctaattgtgt gaacaaggag ccttgattca
     8641 agccaaacaa tgaattttcc atcagcgttt ccgcatcgct tgtttttcct gcttttactt
     8701 gatggaaaaa gttgtcaaaa ctgaacgtgc tgttgctgtg gtaaagacta ttgatgaaag
     8761 gtgtaacttc atgctggaga ccattctcat ctgtcaattt ataatcgatc aggaattgct
     8821 ggaagctttc taaatggata taaatcacat tttttccttt agcgagcccg aacaaatcgt
     8881 catttggtgc tgcataatgt tcttttacat aattttctac ttctttcata tcattgggac
     8941 ttgcttctgc ccgcacttgg tttgtctggt aagtttgaac accgtcataa accatgaaag
     9001 cattcaagcc aagatatttg accaaataat cacgagagaa tgttcgagtc agcaattctg
     9061 gacgatcagc ttccgccata aaaagatttc ctgagaaaat cataactgct aatgtagaga
     9121 tcgcaaaagc cattcttgct cggatcgggc gagggtccaa cttgattttt tttgcaatca
     9181 gcagaacagt caagataata aaatcgatcc aatagatcac atcatatggg cgaaacagtc
     9241 gaatggcact ttctcccaga ccactcgcta ctttcccagc acctaaaatc gtgttgatcg
     9301 taatgaagtc cgtgaattct cgataataag tgacattcga aaaaacaagc aatgtcaaaa
     9361 gaaaataaat gaccatcatc gtgatataag caactctagg gcgtctgata taaagagcaa
     9421 ttccaagtaa taacaatgta gttgcaatag ggttgataaa caagataaag tattgaatgc
     9481 cactttcgat tccgagatgg aaatcaacta aataggcaaa aatcgttttc aaccaaagta
     9541 aaacgactag taaagaaaaa aatccgagcc tcttattcaa aaaggcaggt gtttttatac
     9601 atttcaagat aatcttcctt tctgcacttc ttaatcacag aagtgtcatg aaaccatgtt
     9661 acacagctca cttattctca tttattttac tagtatgaca atatagtgtc aattgaaacc
     9721 agaagtttat gctgtttcat taaggttttc tttaagcttc atgaaaaaat gagcagtaag
     9781 acaagtccta tgttttttgt tatacttggg aagagaaagc taaagcaggt gaaggaatga
     9841 aagtaaaagt aaaaaaaaga gcaagcaatc gattgaaaaa aggatatcca ctgatccaaa
     9901 aagaagacct tgctcatccc caaaaagaaa ccacgcaatg ggtggaatta gttgattcgc
     9961 aaaaccaatt tatcgcaaaa ggatatctag gaaagcagaa taagggaatc ggttgggtat
    10021 tgagccagca gaacatccca tttgatcaat ctttttttga agaatttttt gtgaagtcaa
    10081 aagaaaaaag aactttcttt ttttcagatg attctactac cgcttttcgt atattcaatg
    10141 gagaaggaga cggaatcggc ggtctgattg ttgattatta tgcaggttat gctgtttttt
    10201 cttggtataa cgaaacgtta tatgcacatc gtgaattatt gattcaagct tttcgtgaaa
    10261 tctacccgga aatcgtagga ggctatgaga aaattcgatt tgaatcagta aatctgcctg
    10321 agagccagtt catttacgga aaagaggcac cggaaccctt gatcgtaaaa gaaaacggag
    10381 taaaatttgc cgtttattta aatgaaggat taatgactgg gatcttttta gaccaaaaag
    10441 aagtacgggg atcattagca gaaggtttcg cttctgggaa aacagttttg aacatgttta
    10501 gttataccgg cgccttttct gttgctgccg caatgggagg ggcaatcgaa acaacaagtg
    10561 tcgatctagc aaaacgcagt ttaaaaaaaa cacaggaaca gtttgaagtg aatggtttgg
    10621 atgtcgatca gcaaaaaatc attgttatgg acgtattcga gtatttcaaa tacgccaaaa
    10681 gaaaacaatt tttatatgac atgattgtat tggatccacc aagttttgcc agaaataaga
    10741 aaaaagtctt tcgcgtagca aaagattatg gggaactggt caaggatagt ctggatattt
    10801 tagcagaaga cgggatactt attgcgtcta caaatgctgc gaatgtctcg atagaacaat
    10861 tccaaacaat gattgaagag gaattccatg ccaaaaatgt ttcttttgaa caacttgctt
    10921 tatatcgtct gccaaaagat ttccagacga cggatacctt tttagaaggc aattatctga
    10981 aagtgtttgt ttatcaaatt aaaaataacc attagaagga gcgatgcaga atggtttggg
    11041 taaagggatt gaatatagga agcggtagac caaagatttg tgcgcctctt atcggggccg
    11101 tccgagagga agtattacgt gaagcagttc ttgcacgtga agcaggggcc gatttagtcg
    11161 aatggcgagt cgatcattat cgtgaagttt tttcttttga tgaagtagca gaaacattgg
    11221 ttcttatcca tgagatgctt gatggactgc cgttattatt tacgtttcgt accttagctg
    11281 aaggcggaga acaagacata tcgatccgtc agtatcgcga cctttatgaa catgtgatac
    11341 acacaggatt agtagatatg gtcgatatcg agttgttcaa agtagaaagt ctaggaaaaa
    11401 gactgataga ggaaatcaag tctttaaaca ttcctttaat tatcagtagt catgatttta
    11461 aagaaacacc agcagaccct gtcttgcttt accgattgaa tgttatggaa cattttggag
    11521 ccgatatcgg aaaactggca gtaactccca ataatgaacg agatgttttg cggttgatgg
    11581 agttgactag acgggcaaat gcttttgtct ccatgcctat tattacgatg tccatgggaa
    11641 atcttggtaa aatttctcgt ctggctggcg gaacgacggg ttccgttatg acatttggtt
    11701 ccttaagcag cgattctact tctgctccag gacaattacc ggtcaaagca ttgaagcaaa
    11761 ttattcaatt attaaatgaa ccgttgtaga acaagtttga ggtgatattt tttggcaaag
    11821 aaaaaaatag taaaaacgaa tgcaatccgt atggtcgaac aaaaaaagat tccctataca
    11881 gagcacgaat atgagtggga cgaaagccac ctaagtgcgt catcggtcgc tgaacagctt
    11941 ccagaaagcc aatctcgtat atttaaaaca ctggttgctg tgggcaatgt gacggggcct
    12001 cttgttgctg tgataccggg agaagccgaa ttgaatctaa aaaaattagc aaaagtttca
    12061 gggaataaaa aagtagaaat gctccattta aaagatttgg aagcaacgac cggatacata
    12121 cgtggtggct gctcgcctat aggtatgaaa aaactatttc ctacttattt agatcaaatt
    12181 gcagaaagct atgaacaaat cattgtctcg gctggcagaa gagggctaca gatggagtta
    12241 gcacctcaag atatctgtgc attaacgagc ggacaatttg cagatataaa acaataaatc
    12301 atacgtataa aagaaagaag gaggccggga tgttgtttgt ccagtctcct tctttctttt
    12361 ttatacatta tgctctttgc ccggcattca ttcctgctac atgccctgta gcgaaagccg
    12421 ctgtgatatt aaagccgcca gtataaccat tgacatccag taattctccc gcaaaataca
    12481 gaccatcaat gattttactc tccaatgttt taggataaat ttcctttaga gaaacccctc
    12541 cgccagttac aaatgatttc tcaataggaa aagttttgtt gattgatagc ttaaactctt
    12601 tgcatagttg aacaaaatct tgaatttgtt tttgagaggc ttgttgtcct gtcagatgat
    12661 ccatttcaag ccgctcaaga aagaaaacta acaatcgctc aggcaatata ccatgccaag
    12721 cattgaccaa gttctttttg gttgctttac ttttttctgt caatatatga ataagctctt
    12781 gtttggtttg tgtagggaaa caatccagag aaagtgtcac tggttctccc gttttctcta
    12841 attctttatt gacaaaactt gaacaacgca gtgcagccgg accagaaata ccgaaatggg
    12901 tgaaaagtaa atccatcgta tgttcagtca atacacgacc ttttttattt aaaacgcgta
    12961 aagtgatgtc ttgtaaagaa agcccttgaa gtgttttctc ctgaatatac ggttcatccg
    13021 atatcaaggg ggactctgtc gcataaagag gcgtcaccgt gtgacccact cgcttcacga
    13081 tcttgtaccc atctccagta gaaccagtag atggataagt ccgtccacca gttgttaaga
    13141 taatggcagg agcatggaac tcttcgaatt ccgtgcgtat accgtaaatt ttatgttctt
    13201 tgtggatcaa tttctctact cgagtagaga atagaagcgt cacatctagt tctttcagac
    13261 gattgagcaa tgcttcgata atcgtttttg atttatttgt tacaggaaac atccgtccat
    13321 gatcctcttc ttttaaatgt acgccttgtg attcaaagaa gttcatgata tcgaaattat
    13381 tccattgcgc aaacgtacta tataaaaact ttccatttcc aggaatatgt gcaatcaaat
    13441 catcaacagg acgattgttc gtaacattgc accgaccacc acctgtcatc agtagttttt
    13501 ttcctgcttt tttgtttttt tcgatcaaga gtacgcgtgc gccttgttca gctgcactga
    13561 tcgctgccat catcccgctt gttccagcgc cgactacgat cacatcatac agtttttcca
    13621 ttccctcacc tcaaggaaag tgtagcatat ctgaagaaag aaaacagaaa aaaaatgttt
    13681 tgagccaaaa gagaaaatga gctaaaatga gggaagataa gcaaaggagc gtggaacgat
    13741 gacaaacgca acagaatatg ttcaagcaat tcaagaaaag ctacatcaaa aggatcaagg
    13801 gcaagaagaa tttttacaag caatcgatga attcatgccc acggttatgt cttttttgga
    13861 cactcatccc gaatatatcg aaaagaatat cttagaactt ttaacggaac cagaaagagt
    13921 tattcaattt cgagtgcctt ggcaagatga tgaaggaaac tggcgagtaa atagagggta
    13981 ccgtatccaa tacaactcag ctatcggccc ttataaaggt ggattgcgct tccatcctag
    14041 tgtcaatcta agtatcttga aatttttggc ttttgaacag attttcaaga atagtttaac
    14101 cggtctgcca atcggtggag gaaaaggcgg aagtgacttc gatcctaaag gaaaatctga
    14161 taatgagatc atgcgttttt gtcaaagttt catgctggaa ttgtcaaaac atatcggccc
    14221 atcgattgat gttcctgcgg gagatatcgg tgtaggagct agagaaatcg gctatttgtt
    14281 cggcgaatat aaacgattga aaaaatatga tactggtgtg ttgacaggta aacctttgga
    14341 tttttgggga agtaagatac gtacggaagc tactggttat ggattagtgt attatgtcaa
    14401 acatctattg aacgaagaaa aagattcatt taatcaaaaa acagtttttg tttccggaag
    14461 cgggaatgta gccatttatg caatcgaaaa agtgcaagag ctaggcggga aagttgttac
    14521 atgttcagat tctagcgggt acatctatga tccagaagga atagatgtga aactattgaa
    14581 agaagtcaaa gaaatcaata gacaacgttt gacggaatac gcaaaccaac gtccttctgc
    14641 tatttatcat gctggagaat ctgtttggac attgaaagaa aaagcggata tcgctttgcc
    14701 atgtgctact caaaatgaaa tagacgaaag cttggccgaa atcttagtag aaaatgggat
    14761 caaaatcgta gcagaaggcg ctaatatgcc atgtacagta aaagctgttt ctgttcttca
    14821 tgaagcaggc gtgtggtatt gtccaggaaa agctgctaat gctggaggag tagcagtatc
    14881 tgctttagaa atgagtcaga acgtccagcg attgacttgg gaaagagagc aagtggatga
    14941 gcagctggat caaatcatgg aaacgattta ccatacgtgt cgccaaacag cagccgagta
    15001 cggcgacgaa aaaaatctgc ttcttggagc aaatgttgct ggatttgaaa aagttgccaa
    15061 agcaatggca gcagaaggtt tagtttgaaa aatgaaactt tcttggaaat attgtcagca
    15121 ttttgtttat ttgcttgaaa aataataaaa aaaaacgtaa agtattacct gtagagtaaa
    15181 cctataagga ggagaacaaa tggcacacat tcattttgac tattcaaaag tagcaccgtt
    15241 tgtcaacgaa caagagttag ggtacatgca aagccaagta acagcagccc acaacgaatt
    15301 acgggaaggt actggcgcag gaagcgactt ccgcggctgg atcgatttac caacgaacta
    15361 tgacaaagaa gaatttgcac gtatcaaaga agcagctaaa aaaatccaat ctgattctga
    15421 agtattagtt gttatcggta tcggtggttc ttatttaggc gctcgtgcag cgatcgactt
    15481 cttgaatcac acattcttca atttattaga tagcaacaca agaaaagcac cacaaatctt
    15541 ctttgccgga aattcaatca gctcaacata tattgctgac ttgatcgaag taatcggtga
    15601 tcgcgacttt tcagtaaacg ttatttcaaa atctggaaca actactgaac cagcgattgc
    15661 gttccgtgta ttcaaagagc ttcttgttaa gaaatatgga caagaagaag caaacaaacg
    15721 tatctacgct acaacagata aagcaaaagg tgcagttaaa gtagaagcag atgcagaagg
    15781 ttgggaaact ttcgtgattc ctgatgacat cggcggacgt ttctctgtat taactgctgt
    15841 tggtttgtta ccaatcgctg ttagtggtgc agatatcgat gcattgatgc aaggtgccgc
    15901 tgatgcaagc aaagcatact caagcgacaa actagaagaa aacgaagctt accaatacgc
    15961 agcaatgcgc aacattcttt accgtaaagg caaagtaact gagttgttga tcaactatga
    16021 accaggaatg caatacttct cagaatggtg gaaacaattg tatggtgaat ctgaaggaaa
    16081 agaccaaaaa ggcatctatc cttcaagcgc aaacttctca actgatttgc actctttagg
    16141 acaattcatc caagaaggac gtcgcaatat ttttgaaaca gttgtgaagg ttgaaaaacc
    16201 tcgtaaatca atcacaattc ctgaacaagc agaagattta gacggtctag gctacttgca
    16261 aggaaaagaa gtggacttcg taaatacaaa agcatttgaa ggaacattgc ttgctcatac
    16321 agacggtgac gtgcctaact tgctagtcaa aattccagaa atggatgctt atacattggg
    16381 ttatacaatg tacttctttg aaattgctgt aggtatttca ggttacttga atggaatcaa
    16441 cccattcgac caaccaggtg tagaagctta caagaaaaac atgttcgcac ttctaggcaa
    16501 accaggcttt gaagatcttg ctaaagaatt gaacgaacgc ctgtaagata agggtttttc
    16561 gctagattta aataatcagt gatagaaaca tgttcgcttt aaaatgaaaa ctggtaccca
    16621 tttaggtact caaacatact gcatcgttta ttcagaataa ggggctgtga caagacgttt
    16681 gtcacagtcc cttgtttgta tagaaatcga ttgattgcct tgctctttag tttgttttag
    16741 gactttaaga acagtgaggc tgacttcgaa ggttaattct gtttttttgt tttctagaat
    16801 cagtaagcaa aaaagcactc acttcgagtg cttttttgcg atatattctt agcttaagat
    16861 aggcctaatt tttcttttac agatgagggt accttatcgc tggtaattac ttttttctct
    16921 atgatccgct tttcgcttgc tttcaactgc aagatcgttc cttcggggta agcagaacca
    16981 ttggcagagt caccagaagt aatgacatcg aaatctaact gtcttttttc accgttttca
    17041 gcataagcat ctacgttgta tttaaaacct cttccaatta cttccccatt atctgctttg
    17101 atatcagttt ctgcaggcat tggagctttg actaccgcat aataatcttt acctacataa
    17161 gtagactgat agtagtccca acctttccat cctataaaag caatcaatat gataacgatc
    17221 aaccctaaaa tttttttcat gaaagatctc cttttttatt tttattatac ccgtggtgct
    17281 agttaatttt aatatcctaa agaatatctc aaagttcctt caaaacgtcg ttgtgctcga
    17341 cttaatagaa cactgtaagc cagtaatatg ctttcaaatc tactctctag ccctttaaca
    17401 gaacgtgagt tgaaattttg acaacctaat ttttctaagg aagaaaaaac agtctcaact
    17461 g
//
LOCUS       DACGDM010000048        17344 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.049, whole genome shotgun sequence.
ACCESSION   DACGDM010000048 DACGDM010000000
VERSION     DACGDM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.049"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            1..368
                     /locus_tag="IXR05_001746"
                     /pseudo
     CDS             1..368
                     /locus_tag="IXR05_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            548..1489
                     /locus_tag="IXR05_001747"
     CDS             548..1489
                     /locus_tag="IXR05_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAQ4260242.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1558..2289
                     /locus_tag="IXR05_001748"
     CDS             1558..2289
                     /locus_tag="IXR05_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAQ4260243.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2433..4613
                     /locus_tag="IXR05_001749"
     CDS             2433..4613
                     /locus_tag="IXR05_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAQ4260244.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4633..5115
                     /locus_tag="IXR05_001750"
     CDS             4633..5115
                     /locus_tag="IXR05_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAQ4260245.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5131..5892
                     /locus_tag="IXR05_001751"
     CDS             5131..5892
                     /locus_tag="IXR05_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4260246.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6023..7357
                     /locus_tag="IXR05_001752"
     CDS             6023..7357
                     /locus_tag="IXR05_001752"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAQ4260247.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7785..8270
                     /locus_tag="IXR05_001753"
     CDS             7785..8270
                     /locus_tag="IXR05_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAQ4260248.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8263..8946
                     /locus_tag="IXR05_001754"
     CDS             8263..8946
                     /locus_tag="IXR05_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAQ4260249.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            9072..11717
                     /gene="polA"
                     /locus_tag="IXR05_001755"
     CDS             9072..11717
                     /gene="polA"
                     /locus_tag="IXR05_001755"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAQ4260250.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11762..12598
                     /gene="mutM"
                     /locus_tag="IXR05_001756"
     CDS             11762..12598
                     /gene="mutM"
                     /locus_tag="IXR05_001756"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAQ4260251.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12562..13191
                     /locus_tag="IXR05_001757"
     CDS             12562..13191
                     /locus_tag="IXR05_001757"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAQ4260252.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13243..13575
                     /locus_tag="IXR05_001758"
     CDS             13243..13575
                     /locus_tag="IXR05_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4260253.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13887..14378
                     /gene="nrdR"
                     /locus_tag="IXR05_001759"
     CDS             13887..14378
                     /gene="nrdR"
                     /locus_tag="IXR05_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAQ4260254.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14401..15774
                     /locus_tag="IXR05_001760"
     CDS             14401..15774
                     /locus_tag="IXR05_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAQ4260255.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15774..16700
                     /gene="dnaI"
                     /locus_tag="IXR05_001761"
     CDS             15774..16700
                     /gene="dnaI"
                     /locus_tag="IXR05_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAQ4260256.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16829..17269
                     /locus_tag="IXR05_001762"
     CDS             16829..17269
                     /locus_tag="IXR05_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAQ4260257.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         5908 a         3032 c         3820 g         4584 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tcggaaaaag atcgtcaaga aatggatggg acgcttataa
      121 ttgaagtagg agttgaggac agtcaaacct catttctgtt atatgatcga gcatttgttg
      181 agtcccattc acctggcaca gctactagtg ccccatcttt gatgttttac agtaaagata
      241 tctttggact atataaaaaa atgcagacgc aatcagtcac attaggtgat atggtacagc
      301 ttggagaaga atatgtcttt aactttgctg atcccgatgg caactacttt gcggttacag
      361 gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa caggaaagcg aagtcttttt
      421 aattcaaata ataatattat gtaaacaaaa aactttccat gcgtaattat acacaagcaa
      481 ataaatcgtc aaatgcgaac gccttcttta tactgtttag gaacgaaaag aaggaaggaa
      541 gaaatacatg gattatcaag tactgcttta ttacaattat acaaaaatcg aagaaccaga
      601 ggaatttgcc aaaaatcatt tagccttttg caaatctttg gatcttaaag gtcgtattct
      661 agtagctgaa gaaggaataa atggtactgt gtctggaacc gttgaaaaca cgactgccta
      721 tatgaaagca atgaaagctg atcctcgatt tgctgatacg atgttcaaga tcgatccaag
      781 cgaaggacat gcctttaaga agatgtttgt aagataccgt ccagagcttg taagtttaaa
      841 gctagaagag gacattgatc caaaccaagt gacaggtgcc tatctttcac cgcaagaatt
      901 taaagaagct attttagatg aacagacagt ggtgattgat gcacggaatg attatgaata
      961 tgacttggga cattttcgag gggctgtacg cccagatata cgcagttttc gagagcttcc
     1021 agactggatc cgcgagcaca aagaagaatt tatggaaaaa cgggtagtga cctactgtac
     1081 tggtggcatt cgttgcgaga agttttctgg ttggcttgtc cgtgaaggat tcaaagatgt
     1141 cggacagctg catggcggta ttgctactta tggtaaggat cctgaagtcc aaggagaatt
     1201 atgggacggc aagatgtatg tgtttgatga acggatcgct gtcgatatca accaagtaga
     1261 taaacaaatc gtcggtcgcg actggtttga cggaacacca tgtgaacgat atatcaattg
     1321 tagcaatcct gagtgcaatc gtcagattct tgcttccatt gaaaatgaag aaaaacattt
     1381 aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat cgctatgttc aagaccatgg
     1441 aatctctcca gaagaagcag aactgcggtt tacagcttta attaaataga aaacaatagt
     1501 tttgattgtc gaccatttcc aatatgcgct atactagcgt tgaggatggt gatccacatg
     1561 aaatcattga tttatgctat tggggatgtc catggcaaac atgagctttt tgaaaaactt
     1621 attcactatt atgatccaaa gatccatcag cttgttttat taggggatct caatgatcga
     1681 ggtcctcgta caaaagaatg ttttttatta ggaaagcaat tagtcgaaga aacaggagcc
     1741 atttacctcc ggggaaacca tgaagaatat tttttgcaat ttctgcaatc accggaggac
     1801 tggtatgcgc cttatatgag aaatggtgga aaagaaacgt ttgaaagcct gattcaccca
     1861 ggggcatcgg aggaatactc cccaactgaa atctcgatga tgatccaatc gagatattca
     1921 gaactgatta aatttttagt ccagcgcccc ttgtattatg aatgggaaaa ttatcttttt
     1981 gtccatgccg gtgtggattt gacaaagaaa gactggcgta agacaagtct aagagacttt
     2041 atttggataa gggaaccatt tcatgaaggg aaaaacaata caggtaagac aattgtattt
     2101 ggacatacga ttacaccaat gctccatgga gatatgcaga caacagacct ctggattcag
     2161 gatcataaaa tcggaatgga cggtggggct gtattcggag ggtcattgca tggggttgtt
     2221 tttgacaagg aaggtattct tcaagatatt gaatatcaga acaacgaagg accttggcat
     2281 ggaatctgac taatggaaag aatgaaggag ctgtgacttt gttgcggctc tttttatttt
     2341 tatagagaat attgtttctt tcagtagttt aacccaggat aaaaagtatg atagaataaa
     2401 gaagcaattt ttagcagaaa agaggcattt taatgacgga aaatttgaac cagacgatca
     2461 ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa gcagttgact actgtactta
     2521 atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg ttaccgaaaa gaaatgactg
     2581 gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg gtatgcctat cttgaaaact
     2641 tagaaaaacg taaaactgaa gtgattcggc taatcgatga acaagggaaa ctgactcccg
     2701 agttagaagc agaaatcacc caagccgtga aaatgcaaca agtggaagat ttgtatcgtc
     2761 catacaaaca aaaacgacgg acaaaagcaa cgattgctaa agaaaaagga cttgaaccac
     2821 tcgcgaagtg gctgatgcag cttacagatg gagaggtgca atctgaagca gaaaaatata
     2881 ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt gcacggtgct catgagatta
     2941 ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg gattcggtct tatacgtata
     3001 acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc agatgaaaaa ggcgtatatg
     3061 aaatgtatta tgactttgca gaacccgtcc ataaaatggt ttctcatcga atattagcta
     3121 ctaatcgtgg agaaaaagaa gatattctga aagtattctt tcaagtagat gaagcagcaa
     3181 ttttagctta cttggatcgc caaatagtca aaaatcctgc ctctccttct tcttcattcg
     3241 tcagagaagc ctatcaggat agttataaac gctttattca gccagcaatc gagcgagaac
     3301 tgcgcaatga attgactgaa aaggcagatg agcaagcaat cgctattttc ggcgaaaacc
     3361 tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt tgtcctggga tttgatccgg
     3421 cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac agggaaagtt ttagcaatcg
     3481 aagttattta tcctcataaa cctgcagcgc aagcaaaaag agaagctgct ggaccagctt
     3541 ttatccaatt aattaataaa tatcaagtag atatggtagc tatcggaaat ggtacagcca
     3601 gtcgggaatc tgaacttttt gtggctgagc agttgaaatc cgccgaccat aaaacctatt
     3661 acgctatcgt caacgaagca ggcgcttctg tttactccgc tagcgaaatt gcacgaaaag
     3721 aatttccgca tctacaagtt gaagaaagaa gtgctgtttc tattgcccgt cgcctgcaag
     3781 atcctttagc tgaattagtc aaaatcgatc ctaaagctgt cggagtaggc cagtaccaac
     3841 atgacgtttc tcaaaaacgt ttggctgaac aattggattt tgttgtggaa acagcggtta
     3901 accaagtagg tgtggatgtg aatacagcaa gcccgcagct cttgcagcat atatcaggat
     3961 tgaataaaac aactgcccaa aacattgtca tttatcgtga agaaaacgga gaattcaccg
     4021 cacgaactca attgaaaaaa gtgccacgct taggaccaaa agcatatgaa caagcaatcg
     4081 gattcttgcg agtccctggt gggaaaaaca ttttggacaa cacaggtatc catcccgaaa
     4141 gttattctat tgcaaaagaa atattaactt cagtccaact ttcagaaaaa gagcttggta
     4201 cagaagaagc agtagaaaaa ttgacacgat tatccgtaga gaaactggct gaaagcctat
     4261 cagtcggaga agaaacgtta gccgatattt tagctgggct gacacaacct ggacgagata
     4321 tgcgtgatga gatgccagcg cccttattac gtacagatgt attgagtatg gaagacttga
     4381 aaccagggat ggaattgact ggaacggtcc gtaatgtcat tgacttcggc gcatttgttg
     4441 atatcggtgt gaagcaagac ggacttgtcc atatatcgaa actcagcaaa aaattcgtca
     4501 agcatcctac agatgtcgtg tcagtaggag atatcgtaac agtttggata gaacaagtcg
     4561 atacgaaaaa aggcagaatc agtttgacga tgctttcccc ttatgaagag taacaatgag
     4621 gagtaacaaa aattgacaca agaagaactg cagcagttag tagaagagat atcattaaaa
     4681 agcttccagc ttcctttcaa gcaccaagca atgttcaatc cacgcttacg tacaactggc
     4741 gggcgctatc atttaaacga tcatcattta gattttaatg cgaagctatt tgaagagtca
     4801 gacgaagaga cgattgcagg aatcatcaaa catgaacttt gccattatca tcttcatcta
     4861 gctggaagag ggtatcagca taaagatatg gatttcaagt atcttttgaa aaaaacagga
     4921 gggttgcgct atgcaccagc cttgacgaag aaacagataa agatggagta ttatcgatgc
     4981 caagattgtt ctgccacgat ctgccgcaag agaagaatcg atgtacgcaa atatcgttgt
     5041 ggaagatgtc atggagaaat caaatggatt gagacaaaaa gagaagactt taatgaagca
     5101 caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa gtgagcagag gaatctaaaa
     5161 gactggaatc agctattaaa ttttttagcc gcacctgaag agggaaattt tgaggaactg
     5221 acggcaccta cacttatttt agctggaaac tgtcttccta tcttagctga taaagcagca
     5281 caaatgtatt taaatggcca agtagatcaa ttgtttttgg tcggaggggt ggggcatgcg
     5341 actagaatcc tttatgagaa ttttgaaaag caaggatttc attttgaaga tggcatgagt
     5401 gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg atttgcccga taaggctttt
     5461 ctgatagaat cgaagtctac aaattctgga gagaacgcca ctttttcact ggagattctt
     5521 cattccttag gagctgtacc agaaaaaatc ttattgatga atgatccgac actgcaacgc
     5581 aggactcgag caacttttga gaaagtatgg caaaatgaac aaactatttt cgcgaatgct
     5641 gtgccatttg tgccggaaat ccttcacttt tctgaagaga tcatctttac agcaaaagaa
     5701 ctgaatcatc aatggcctaa ggaatatttc catgcgctag tattaggaga aatggaacgt
     5761 ctccatgacg atgagaacgg ctatggtccg aaaggaaaag attttattcc tcacattgat
     5821 atatcagagg aagtttggtc ttcttacacc agaattaaag agtcaataaa aacggatttt
     5881 tcccgtactt gaccatttta gcaagcgaat cctcctttcc aaataaattt ggttgaaatt
     5941 ttcaatcgtt tataagataa tgaggagcgt gttgaatgta atagctaaaa gaatggacgc
     6001 tagataagag aagaggattc aaatggaaaa tcaaaataaa ttgtatcatt ttgttggtat
     6061 caaaggttca ggaatgagct ccttggctct tgttttacat gaacaaggtc taaatgtcca
     6121 aggatcagac attgaaaaat atttctttac acaaagagat ttagaaaaag caaatatcac
     6181 gattctgcca tttaacgcag ataatgtaaa accagggatg acgatcattg caggaaatgc
     6241 atttcctgat tcacatgaag aaatccagcg agcaaaagaa ttaggtttgg aagtgattcg
     6301 ctatcacgac tttattggtc attttatcca aaattatacg agtatcgctg taacaggctc
     6361 tcacggaaaa acaagtacga ctggactgct ctctcatgta ttgagtggtg tccgtccaac
     6421 aagttatcta attggagatg gaacaggaca tggtgatccg caagcggaat tcttttcatt
     6481 tgaggcctgt gaatatcgcc gtcatttcct tgcctattca ccagactatg caatcatgac
     6541 caatatcgat tttgatcatc cggattatta tacaagtatc gacgatgtat ttacagcttt
     6601 ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg tatggtgacg atgcttattt
     6661 acgcaaatta aaagcaaatg tgccgattta ttattatggt gtcacagaaa acgatgatat
     6721 ccaagcacga aacatcgaac gcacaacttc tggttctgct tttgatgtct atcatgggga
     6781 tgaatttgtt gggcacttca ctgtaccagc attcggtaaa cacaatatct taaatgcttt
     6841 aggtgttatt gcagtagctt atttcgaaaa actggatctg aaagaagttg cagaagaaat
     6901 gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag atcgtagcag acatgaccgt
     6961 agtcgatgat tatgcgcatc accctgcaga gatcaaagca acgattgatg gcgcacgcca
     7021 aaaatatcca gataaagaaa taattgcagt tttccaaccc catacgttta cgcgtacgat
     7081 tgcattgatg gatgaatttg cagaagcact tgatttagct gataaagttt acttatgcga
     7141 tatttttggt tcggctcggg aagaacaagg aaacgttaag attgaagacc ttggagcgaa
     7201 aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta tctccattgt tagattatca
     7261 tgatgcagta gtaatcttca tgggtgctgg agatgttcaa aaatttgaac aagcgtatga
     7321 aaaactttta agcagcacga cgaaaaatgt actgtaatac aattactgca gtgtccttat
     7381 aaaaatagaa agagggggag tggcaaaaat cttgccaagc cccctttttt gcaacttatg
     7441 ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc caatcaaatc aaaaacatga
     7501 gaagctgttt ttcttggctg ttcttattac ttgatgcagg gcagcttttt cacgacctca
     7561 gataaacggt gttcaaaagc ttgcatctgc ggtaataagt ccagccaaat gaaaaatatg
     7621 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7681 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7741 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7801 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7861 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7921 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7981 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     8041 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     8101 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8161 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8221 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8281 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8341 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8401 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8461 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8521 tactctcttt tgaatggcat aacattagcg gttactcttg catactacga tattggaaca
     8581 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8641 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8701 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8761 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8821 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8881 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8941 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     9001 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     9061 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9121 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9181 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9241 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9301 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9361 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9421 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9481 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9541 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9601 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9661 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9721 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9781 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9841 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9901 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9961 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
    10021 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
    10081 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10141 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10201 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10261 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10321 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10381 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10441 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagataaa aaccaagaag
    10501 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10561 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10621 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10681 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10741 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10801 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10861 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10921 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10981 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    11041 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    11101 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11161 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11221 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11281 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11341 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11401 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11461 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11521 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11581 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11641 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11701 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11761 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11821 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11881 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11941 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    12001 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    12061 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12121 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12181 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12241 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12301 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12361 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12421 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12481 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12541 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12601 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12661 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12721 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12781 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12841 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12901 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12961 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    13021 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    13081 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13141 aaacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13201 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13261 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13321 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13381 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13441 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13501 gaccacattt ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13561 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13621 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13681 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13741 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13801 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13861 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13921 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13981 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    14041 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    14101 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14161 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14221 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14281 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14341 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14401 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14461 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14521 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14581 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14641 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14701 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14761 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14821 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14881 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14941 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    15001 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    15061 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15121 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15181 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15241 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15301 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15361 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15421 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15481 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15541 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15601 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15661 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15721 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15781 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15841 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15901 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15961 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    16021 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    16081 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16141 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16201 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16261 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16321 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16381 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16441 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16501 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16561 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16621 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16681 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16741 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16801 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16861 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16921 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16981 atttgtcgga acgattgaaa gtattactca agtagaagca gaagaagaaa cgcttcagtt
    17041 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    17101 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17161 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17221 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17281 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17341 tggg
//
LOCUS       DACGDM010000049        17077 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.050, whole genome shotgun sequence.
ACCESSION   DACGDM010000049 DACGDM010000000
VERSION     DACGDM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.050"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            179..1348
                     /locus_tag="IXR05_001763"
     CDS             179..1348
                     /locus_tag="IXR05_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4260258.1"
                     /translation="MKLRANIIEKRGTLQVVVSYKDSNGKIRQKWKDTKLKKKGNKKR
                     AEKIRDEFLLELESQLAMECECANPNLLFYDYLLNYLEVSKKQVAFNTYVGYKHYVHN
                     RIYKFFYPKKIKLNRLKPYHLQEFYQYMLNDNCTANTVIHYHAFIRKALQEAVITELI
                     STNVADKVRKPKKKQFVSQVYNQQEILKLLDILSEEKLYLVVLLTAFYGLRRSEVLGL
                     KWSAIDFLNKKIMINHVIIENPENMSQLIKKDQTKNSSSYRTLPLVETIERALVNQAK
                     WQQDNRILLGDDYILEDNEYVFTMEDGRLMKPQYVTHRLSKLIKKNGLKKIRFHDLRH
                     SNASIMLDSGQNMKSIQEWLGHASYSTTANLYTHLTAGVKDRAAEALENAFGFKE"
     gene            1922..2491
                     /locus_tag="IXR05_001764"
     CDS             1922..2491
                     /locus_tag="IXR05_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAQ4260259.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            2478..3338
                     /locus_tag="IXR05_001765"
     CDS             2478..3338
                     /locus_tag="IXR05_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4260260.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            3528..4232
                     /locus_tag="IXR05_001766"
     CDS             3528..4232
                     /locus_tag="IXR05_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260261.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            4237..6072
                     /gene="walK"
                     /locus_tag="IXR05_001767"
     CDS             4237..6072
                     /gene="walK"
                     /locus_tag="IXR05_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAQ4260262.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6069..7385
                     /locus_tag="IXR05_001768"
     CDS             6069..7385
                     /locus_tag="IXR05_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260263.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            7386..8255
                     /locus_tag="IXR05_001769"
     CDS             7386..8255
                     /locus_tag="IXR05_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260264.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            8310..9119
                     /locus_tag="IXR05_001770"
     CDS             8310..9119
                     /locus_tag="IXR05_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4260265.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(9222..9851)
                     /locus_tag="IXR05_001771"
     CDS             complement(9222..9851)
                     /locus_tag="IXR05_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAQ4260266.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10021..11313
                     /locus_tag="IXR05_001772"
     CDS             10021..11313
                     /locus_tag="IXR05_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260267.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(11389..12051)
                     /locus_tag="IXR05_001773"
     CDS             complement(11389..12051)
                     /locus_tag="IXR05_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4260268.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            12276..12560
                     /locus_tag="IXR05_001774"
     CDS             12276..12560
                     /locus_tag="IXR05_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAQ4260269.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            12611..14236
                     /gene="groL"
                     /locus_tag="IXR05_001775"
     CDS             12611..14236
                     /gene="groL"
                     /locus_tag="IXR05_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAQ4260270.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(14325..15473)
                     /locus_tag="IXR05_001776"
     CDS             complement(14325..15473)
                     /locus_tag="IXR05_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4260271.1"
                     /translation="MLKVWVEQTKDGQFKFIERYVDPYTEKTRKKSTTLTSNSPQAWK
                     KAQKILDKKIKEALEDYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHI
                     SDDTIVRNIDETLINKIIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPAL
                     AVKIHPKKVEEEKRRLSMNKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRY
                     GELLALQMKDYEDGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLPNRAKELIES
                     VIADNILAGRPTDPDQYIFISTSGTPLALHSFNAILHKVEEELELEKSLSSHIFRHSH
                     VSLLSELGVPLKAIMERVGHSDANTTLSIYNHVTKRAKQQVIDKLNSL"
     gene            complement(15575..16159)
                     /locus_tag="IXR05_001777"
     CDS             complement(15575..16159)
                     /locus_tag="IXR05_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAQ4260272.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(16286..16717)
                     /locus_tag="IXR05_001778"
     CDS             complement(16286..16717)
                     /locus_tag="IXR05_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4260273.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFEYSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(16735..17055)
                     /locus_tag="IXR05_001779"
     CDS             complement(16735..17055)
                     /locus_tag="IXR05_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4260274.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
BASE COUNT         5650 a         2881 c         3453 g         5093 t
ORIGIN      
        1 gcttataatt tgctgaaaga tagatcaata gaaaatataa aaattggagc aaggtacaaa
       61 atacctaaaa aagctgtcat tgagtatata ttgaaaatac aagatgaagg taaaaatcat
      121 gctataataa aatagtcaaa atttttgccg atatttcagt ttaagaggag agattgaatt
      181 gaaattaaga gcaaacataa ttgaaaaaag aggaacatta caagtagttg tatcttataa
      241 agactctaac ggaaaaatta gacaaaagtg gaaagataca aaattaaaaa agaaaggaaa
      301 taaaaaacga gcagaaaaaa ttagagatga atttttacta gaattggaaa gtcaattagc
      361 tatggaatgt gaatgtgcta atccaaattt attgttttat gactatttgc ttaattattt
      421 ggaagtatca aaaaaacaag tagcatttaa cacatatgtt gggtataagc attacgtcca
      481 taatcgaatt tacaagtttt tttatcctaa aaaaattaaa ctaaataggt taaagcctta
      541 tcatttacaa gagttttatc aatatatgtt aaatgataac tgtacagcaa atacggttat
      601 tcattatcac gcatttatac gcaaagctct tcaagaggct gttattacag aattgataag
      661 tacaaatgta gcagataaag taagaaagcc aaaaaagaaa caatttgttt ctcaagttta
      721 taatcaacaa gagatcttga aattacttga cattttgtca gaagaaaaac tctatttggt
      781 agttctttta acagcatttt atggattgcg aagaagtgaa gttttaggat taaaatggtc
      841 tgctattgat tttttaaaca aaaaaatcat gataaaccat gtaatcatag aaaatccaga
      901 gaatatgtca cagttaataa agaaagatca aacaaagaac tcttccagct atcgtacatt
      961 acctttggtt gaaacgattg aacgagcatt agtaaatcaa gctaaatggc aacaagataa
     1021 tcgtattctt ttaggagatg attatatttt agaagataat gagtacgtat ttactatgga
     1081 agatggacgg ttgatgaagc ctcaatatgt aacgcatcgt ttgagtaagt tgattaagaa
     1141 aaatggattg aaaaaaattc gctttcatga cttgcgtcat tctaatgctt caataatgtt
     1201 agatagtggc cagaatatga aatccattca agaatggctg ggacatgcat cgtattcgac
     1261 aactgctaat ttatacacgc atttaaccgc aggagtaaaa gatcgtgcag cagaagcatt
     1321 agaaaacgca tttgggttta aagaataaaa aaacaaaaaa caatatcttt ggggtatcgc
     1381 ttcttgtttt tagaattttt ttgttggcaa tttgttggca gtatgttggc aatgaaaaaa
     1441 ttcacaaact aaaaacctat ttataaagct ttataaaact tttttcacaa atagagcatt
     1501 tggttaagag tcagctgctc taccaactga gctaacggcc cgtacaaaaa gtacttaata
     1561 atagtagcac taagaatttt aaaatgcaag actacattta aagaaaatca gaaaaatctt
     1621 tacttcctta taggaaatca ttcatagatt attcacattt gctcgctatt atataagcat
     1681 accaacaaac aaagttcttg caagagaaca aaccctaaca cttttttcat tttttactcc
     1741 tttcccgccg tctccccggc gggtctcctg ttcttaacga taaaagacaa gaaggcttag
     1801 ccttcttgtt ttttgttttc atggaatccc gctaatcaaa tcacctagtt aaagcaacta
     1861 gattgaatgt ttatcataag tctgatatca tgtttatgaa atgaaaaaag gagcggttat
     1921 gatggaaaaa atgcgtcagc aattaatgga gtgggggaag gaactagaaa cattccgtct
     1981 gcctcactgg gaagaactcc ctgacttaga actttatatg gaccaagtca gaacgttagt
     2041 tgatcgttat ctttcacctg tgatacaagg agaaaagcat ccattgctta cctcttctat
     2101 ggtaaacaat tacgttaaac taggtttgat accagcacca gttaaaaaaa gatataacaa
     2161 agaacacgta gcatttttac ttgcaatcac tacgttgaaa caagtattga ctattcctga
     2221 aatcaaagaa gggatattgt tccaaggaaa aacagtagga attcgtgaag cctataatct
     2281 attttgcgat gaacaagaag cagctgtgtg gatggtcagc caattagcac aaggtaaatc
     2341 tcatccgcaa aaattcgacc aggcaacccc tgtagaatat attgctgtaa gagcggcaac
     2401 tttatcgttt gcaatgaaac ttcttgcgga aaaaacgatt gttctagaaa ccgaatattt
     2461 aaaagaggag aaaacaaatg aaaaacaata aaatcgcaat tttagtagat tcaggtacgg
     2521 atgttccaga agaattgata aaaaaatacg agatgtatat gatcccattg aaaattattt
     2581 ataaagatca ggtatataca gataaaattg acattacccc tgaagagatc tatcaacgtt
     2641 tgccagagga aatccctggt acatctttgc cggatggtga gtcgatcaca gaaatctttg
     2701 agcaaatcaa aaaagacggt tatgaaaagg tacttgcggt aacaatttcc agtggattga
     2761 gcgggacata taatgtggtt cgtttaattg cacaacagca agaagaattg gaagcatatg
     2821 tactagatac gaaaaatatt ggtattggtg caggtttttc tgcgatccaa gcagcaaaat
     2881 ggctggaaga aggagtagaa tgggatcaac tgatcagtaa tctgaatgag ttagtcgaaa
     2941 gaacaaaagt tttctttaat gttgcgacat tggaatatct tcaaaaaggt ggacggatcg
     3001 gtttagttgc ttctattgta ggaaccgctt taaagcttaa cccaatcatc tcatgtaatg
     3061 aagaagggat ttattacaca gtaggaaaag ctaggggacg taaaaaaagt ttggataaaa
     3121 cggttgctta cgtcaaagaa aaaatcggta atgcaaaggt cttcaactta gctgttgccc
     3181 atggggatgc gaaagaagaa gcaattgaaa tggaagcgag acttaaaaga gagttcccac
     3241 aagcaaacca aatctacttt ggccagattt ctccggcatt agtagtccac actggtccgg
     3301 gattattggg tgtcggtgta caagttttag aaggataaat caaaaaaagg aaacactgag
     3361 gtgaaaatca gtgttttcct tttttattga agttagaaca aaaaataata aagtattttg
     3421 cactttcatt ttaattttct cttttgtttt ataggcaaag atgaaacaaa agcagaaata
     3481 cggtataatg agaaggtatg acaataatat ataagaggtg gctctttatg aaaaaagttt
     3541 tagttgtcga tgatgagaag ccgatttcgg atatcgtcaa attcaattta gccaaagaag
     3601 gctatgacgt ttatactgca tatgatgggg aagaagcctt ggaaaaagtt gctgaggtag
     3661 aacctgattt gattttactt gatttgatgc tacctaaaat ggacggctta gaagttgctc
     3721 gtgaggtacg caaaacttat gatatgccga tcattatggt aacagccaaa gattctgaaa
     3781 ttgataaagt cctaggctta gagttaggcg ccgatgatta cgtgaccaag ccattttcca
     3841 accgagaatt agttgcacgt gtcaaagcaa atcttcgtcg cggtgccacg gctgcgaagg
     3901 aaccagaaga ggcagcacct gcggaattga cgattggtga tttgacgatc catccagaag
     3961 cttacatggt gacgaaacga ggagaaacaa tcgagttaac acatcgtgaa ttcgaactac
     4021 tcttttactt ggcgaagcac cttggacaag tgatgacaag agaacattta ttacaaacgg
     4081 tttggggtta tgattatttt ggagatgtac gaacagtgga tgtaactgta cgtcgtttgc
     4141 gtgaaaagat cgaagataat ccaagccatc caaattattt agtgacacgt cgtggtgtcg
     4201 gttactattt gcgtaaccca gaacaggagt aattggatga aaagaaaagt ccgctttttt
     4261 cgatcagtca attttaagat cgctattacc tttattctga ttttattgat ctcgatcgaa
     4321 attattggtg cctactttat acgtggttta gaacgttcca cgatcaatac atttattaaa
     4381 gatatgaatc aaacggtgga atcattagca acaacaatca gcccggaatt gaatcgaaaa
     4441 gataatgcag atgatgaaga ggtaaatgcg aatatcaaaa gatttattga aaacagtgcg
     4501 actagcgata tcatcgaaat acgggtcgtt gacgaaaaag ggatcatccg aggaacaacc
     4561 gatgtcaatg aacaaagcgc tgtgggaaag aaaaatgatt atgttgatat caatgatttc
     4621 acgactaaac gttatgttgc tttagataac gacgataaac gggtgaatat caatgttcaa
     4681 ccgatcctgt ccccgaccgg cgatgccgtt atcggggctc tttacgtcaa aagtaatatc
     4741 gaacaaaaat attcggaaat caataacaca gcagtcattt tctttactgc ctcactaatt
     4801 gcggcattta tttcaatgat cgtatctgtt ttagttgctc gttcgattac acagccgatc
     4861 ggtgaaatga gagaacaagc cattcgaatc gctagaggag actacagtcg gaaagtcaaa
     4921 gtgcatggac aagatgaact tggacagctg gctgatacct tcaatcagtt agctgaacgt
     4981 attgaagaag ctcaagatac aatggaagct gaacgcaatc gtttggatag cgtgctatcc
     5041 catatgacag acggcgtcat tgcgacagat cgcaggggta aagtcattac gatcaatgat
     5101 atggctgttt ccttgctaga tatcaaaaac gaggaagcaa tcggacaatc gattttgaca
     5161 cttttagata tcgaagaaga atatacgttg cggaaattat tagaagatcc aaacgaaatg
     5221 gtacttgacc gttcaaccag tacattggaa agtgatcaga tgatcttgcg agtagacttt
     5281 tctatgatcc gtcgcgaatc aggttttatc agcggattag tagctgtctt gcatgatgtg
     5341 acagaacaag aaaaaacaga acgggaacgt cgtgaattcg tctctaatgt ttcccatgaa
     5401 cttcgtacac cgttgacaag tatgcgtagt tatatcgaag cattgagcga aggtgcgtgg
     5461 aaagacgagg aagtagcacc aaattttttg aaggtaacgc tagatgaaac agaccgaatg
     5521 attcgaatga tcaatgacct cttaaatcta tctcgcatgg atacaggtaa tacccagctt
     5581 caattagaat atgtcaattt caacgagtta gtgaattttg ttcttgaccg gtttgatatg
     5641 atggtgggaa atcaggaaaa aaattataag atccgtcgtg aatttacgca aagagatctt
     5701 tgggtcgaag tagatacaga taaaatcatc caagtagtcg ataatatcat gaataacgcg
     5761 atcaagtatt caccagatgg gggaacgatt acttgtcgct tattagaaac gcataataac
     5821 gtgattttaa gtatcaccga tcaaggattg gggattccta aaaaagatct gaaccgagtg
     5881 ttcgagcggt tctatcgagt agataaagca cgtgcaagag cacaaggtgg gacaggactt
     5941 ggattagcta tttctagaga agtgattaag gcgcatcgag gcgctatttg ggcagagagc
     6001 aaggaaggaa aagggtcgac tttttatatc tcgctgccat atgaacctta tgaggaggaa
     6061 tggtgggaat gagaatctct gaaaaagtcg ttcgtatagg actcattttg atggttgcgt
     6121 taagcatata cttctcttat gcaatctggc tgagcccagc aggaaaaagt tcaatcaacg
     6181 tagatgagac aaacactcaa atgatcgagt ctcaaagcaa tcgaaaaact tccgaagtct
     6241 ttcttccgct tcatgttaca tggcaccatt cgggaatgat ccaagaaacc aacagtgaaa
     6301 atctcgtgta ccgattgcaa ttgatcatcg ataaagcaag atttggaaag ctttctgaag
     6361 tagtttcagg agacaaatca cagtttgaac aggtgaaaaa tctgaactct ggttttgagt
     6421 tggcctataa tgcgcctttt ttgctaagag aatacaagga agcatttgat ttagatttag
     6481 atgtgtcgaa cttggcaaaa gaaagcgaaa atatgtattt tactagaata caattcgatc
     6541 aaggaaataa aaaaatccga tttttgaatt attcgaacca tctcgtatat gaagcaaata
     6601 tttcgttgaa ttggacagat atcaataaag aattaacagc aaaagacaca aaatggacag
     6661 aaatgacaac agaaccatcg acgatcgaca cgcaatatgc tacgaaacat tcgatcaaac
     6721 tgaagaagta tagttatatc ctgtcacagc aaccctatac actttttaga aatgcttttt
     6781 tccagaaacc agatagcgtg aaaaataatg atgaaagcaa tgaattgatt ttttacggtg
     6841 ggaatgaaac aatgtctatc cattcggaaa cgcaagtagt tgattttcgt ggagagctgc
     6901 cagagaaaaa agaaaatgct agtgtatttt ctgaaagttt cccctatatt agcaaattag
     6961 gcagttcttt agggaacctc agatattttg accgcagtga caatacgatc gattatcgga
     7021 tattcgtgga aggcttcccg gtttttggga cagacagcag aggacagatt ggtgtggaag
     7081 ttggcggtga aacgaatggt tctgtgcaag tgaatatcca aaccagtttg aatacgattc
     7141 aagtgccgat accttcagac gaagaagtag aacttgcaag tacgaatgaa atcatccagc
     7201 agttaaaagc taagggagca gatagcaaca agattggttc agtgatcgtt ggctatacat
     7261 ggcaaaatgt caaagaaacg aatcgtgtcg ttgatctctt acctgaatgg tatgtgaaat
     7321 ataaagataa ctggtattca gctaacgacc ttctggaaaa attacctgga ttggaggcga
     7381 attaattgga tttcaaaaaa atcgaatgga tatttttcgt cgctttttta gggttgaatg
     7441 tgtttttatt cagcagttat catgacgcgg tataccaaga aaacaatgtc attcgctcta
     7501 atcagactga atcaatccaa caacgtctgg ctagcgacga tatcacttac acggggaaga
     7561 tttcgtctga gaacaagcaa ggctattatc ttagcgcgga gcagaccaat cttagcactt
     7621 cattagcgaa ttatcgcaag gctggtaaaa gcggcttgct ggcaagtggt gtgtttttag
     7681 acggtgatgt tttgacgaaa tctttatcca gttcagatgc tgaaaagaac gtgatcgatc
     7741 cagataaaat tagtagttcc ttggaagatt ttttatctaa caaagacaat attttattcg
     7801 gtaatgatta tgtgtacacg aaaaactttt ctcatttaga agaagaacca ctagaaatcc
     7861 aagcaagcca agagtatgaa ggcatcccat tcaatgatga tacagcaaaa atcgttcttt
     7921 ctttagaaaa aaacgataat gattatagca tcacgaaata catgcagacg catttatctg
     7981 atatcgagca gctgcgcgaa aagacggaac tgtatacgga agaggaagca atcaatacat
     8041 tgtacatcaa taacaaaata ccaagaggat caaaaatttt atggcgtcag ctagcttatt
     8101 cctgtattct gaaagtccgg gaaaaaaatg tgtatgttcc tgtttggcat gtagcgatcg
     8161 aaacaagcga taaagtggtc caaattgaga gcgtcaacgc tttcagcaat acgatcgtga
     8221 caaacaatac tgtaccaaaa gtggaagatc aataaaaaag cgagtataat gaaaaaagtt
     8281 tacaaagtaa gaagggaagt aggagtcaaa tggctgaaga aaaaccagct tttaaaatca
     8341 gtatcctagc aagtggaagt tcgggtaatt cactttatat cgaaagtgaa aaaaaacggc
     8401 ttttggtcga tgcaggactt agcggtaaaa aaatcacttc cttgatggct caaattgatc
     8461 ggacaccgga ccaattagat ggaatacttg tgacgcatga acatcgagat catatacatg
     8521 gcgtgggtgt cttggctcgt aagtatcatt tggatgtttt tgccaatcag cagacttggg
     8581 aagcgatgga accactgatt ggaaatgtac cagtggaaca aaaacatcta tttgagatgg
     8641 ggaaagtcag aacattcggc gatatcgata ttgagagttt cggcgtctcc catgacgcag
     8701 cggctccgca attttatcgt ttccataaag aaaatcggtc attcgtcatg ttgacggaca
     8761 ccggatattg cagtgattat atgcgaggtg tcattgaaaa tgccgatggt tatttgatgg
     8821 aaagtaatca tgatcttgag atgttacgca tgggacctta tccgtggaat ttaaaacagc
     8881 gtattttagg agatagagga catctttcca acgaagacgg tgcacttgtc atgactgatg
     8941 tgatcggtaa tcggaccaaa cgaatctatc ttggccatct tagcaaggaa aacaatatga
     9001 aagaacttgc tcatttaaca atggaaaatg ttttgaaaga aaaagatttt ggcgttggac
     9061 atgattttga aatctatgat acagatccag atgaagcaac tgagctattt tcgatttaaa
     9121 cagttcaatc aataaaaata taaaaagcag aagataaaat caatcagggt tggttttatc
     9181 ttctattttt atttttttag catattaaaa aaataaccgt attatcgact gactacactg
     9241 atgtgctgct tttcatgttt ctcatccagt atctcatcta ctaatgcaat cgcgtaatct
     9301 gccatgctga tcgtactgtc gctagcagcg tttctttgta aataatcatc acttaacaaa
     9361 taagtacctg tacgtttgcc atgtggatca aataaagaag ctggactgat ataagtccaa
     9421 tgtagatttt tagattgttt caattttaac aatccttcgt acatattgaa agctgttgga
     9481 tagaagggtg catttttagg tacttggtca atcatacgag tcgtcttttc tgtatctaag
     9541 aataacgaag aggcaccccc aacgacaatt aagcgtgtat cggttccttc aagcatctca
     9601 atcaaatggg acaaagaagt ttgatgcatt tcttcttttc ctttgggagc gttgaaagca
     9661 tcaacgacaa catcaaaaga tgcaagatca gtagttgtca actcaaataa atccttttgt
     9721 ataaacggaa catctgatgg caatttttct ggatgacgca cgattgccgt cacgtctaaa
     9781 tctctggaca atgcttcgtc taaaataaat gaacctgcat ggccagtagc tccaatgagt
     9841 gcaattttca taaaaaacct ccttttttat tcctgtccat tgtaagcagt tgctgaatat
     9901 tcgtcaaaga atccgatttt tgaaaagctc agtgcgcatt cctttcatgg ttcgtgatca
     9961 ttgggtatag ttaaattaag aaaactgatt gataaaaata gaagttgaag gagataagaa
    10021 atgaaagagt ggttagatcg tgccttttta ccaatgataa catctgttgt gaatcttaga
    10081 cccttaactg ctttgcgtaa tggaatgact tacacgatcc caataattat tgttggctcg
    10141 ctgtttttct tatttgctca ttttcctgtg gattacatcg ctcagtggat agacaaaaca
    10201 ggattttcta tgtattttac acaagtatac caggctacat ttgatgtgat agccttttgg
    10261 atcgtttttg ccattgcata cgcttatgca aaagaagaag acatcgatcg cttaccagtc
    10321 ggcataacag ccttgtctgc ttatctactg cttattcagc cactaaatac tcagatagat
    10381 actgtctgga caggtgctga agggatacta ggagcagtta caactgggct catcatcgga
    10441 tggggctatg cacgtttagt aagacttgcg aaagggtgga agcaaagaga gaagatacct
    10501 gaaaatgttt ggcagtcttt tacttcattg attccaatca ttgttatagt cacttttacg
    10561 cttatcggtt cagcggtttt tcaacatttg ttcagaatga ctgttgttca aggagtatgg
    10621 acatatgtcc agcttcccat tcaatcgttc atagacacgt tgtttggtgt gcttttatta
    10681 ggtttttttg ttccgttttt atggttattt ggtcttcatg gatctgcgat ggtcaatggg
    10741 ttggttagtc ccgtcttgca agcgaattca ttagcaaatg cagaaatctt agcctcagga
    10801 caagagttga cggtggcaaa tggcggacat atcgttactc agcaatttct cgatcagttc
    10861 atgacggtta cgggtgctgg attgacgtta ggggctgtat tttttatgac ggtttttgcg
    10921 aaatcgaaga aatacagaga attaggaaat cttgctcttt taccagcctt tttcaacatc
    10981 aatgaatcaa ttattttttc cacaccgatc gtgatgaacc cgatgatggc tgttcctttt
    11041 attttcgcac cggtcgtttc aggattgatt acctattccg ctttatattt tggattcgtt
    11101 cctttattta cagcagtcca agtcccttgg acaacaccgc cgatcctctc gggtttctta
    11161 gtaggcggag tgcctgcagc gattttacaa ggtatcgtgt tgtcaattag ttttttcatt
    11221 tatttcccat ttttgaaaaa aatagattct gcaaactgca aaaaggaaag acagacaaaa
    11281 aatgatggag cagcagaaaa gatgaacgac taaaaaacaa aaatactcct gtcgctttag
    11341 attgggaaaa tcaccaatct aggatgacag gagtatttat agtcatgttt atactagccc
    11401 tttttggaca gctaattgaa caagaacaac taatgtgttc attcctacgt gtgtgatcat
    11461 cgatgtccag atccgaccag ttgctttgta ctctaggctg aagaagaaac ctaggaaaaa
    11521 gtagattagc agatgaccat cattatgagc aaacgcaaac agcaaagagc tgatcactgc
    11581 tccgacccaa aaatttgaat atcgactgat gatccccagt atactgcggc ggaatacgaa
    11641 ctcttccatg atgggtccag caacagttgt cgccaaaata aaagcgggtg cttccatgat
    11701 catctggatg atattttgtg tattctcgga aggggttgct ttgccaaaca atacagattc
    11761 taacatgaca gcgatgcttt gcagaatcaa tgcgacaaag attccaacca atccataaat
    11821 aacaatcttt ggagcagaag ctttttttac cgctgattcg atcgctaagg gttcacgttg
    11881 cttaaaataa aaaatagcta ggacaacggc gcctagtata tacatgactg cagttgctgt
    11941 gatcaattca gacgtagatt ttacaagtcc tatcgaagct aggatcaagg gtgagataaa
    12001 aattagacca tagcaaaaaa tgctgaggaa gctatatttt tttaaagaca tgtaattcct
    12061 ccttttaagg gataacaagc atgcaaggca agcttatatc gattgatttc aattatatca
    12121 taatttcaat aagcagctgt cagaataaaa tttcttttct ttgatttaaa agcttgcaaa
    12181 aaagagggag aatgagtatt attaaaaatg taggttagca ctcgaaggtt aagagtgcta
    12241 acagattaaa aaaagagtta tcggagggat ttatcgtgtt aaaaccatta ggtgatcgcg
    12301 tcattatcga agtcgcaaaa gaagaagaaa aaactgtcgg aggaatcgtt ttagcttctg
    12361 ctgctaaaga gaaaccccaa actgggacag ttgttgcagt cggtgaaggc cgtttgttag
    12421 aaaacggtga aaaagttcct gccgctgtaa aagcaggcga ccaagttatg ttcgaaaaat
    12481 acgccggtac agaagtaaaa tacgaaggaa aagaatatct gatcgtcgca ggaaaagata
    12541 tcatggcgat tgttgagtaa atttggaaga taaaaaaata atcaaaaata atcaatgagg
    12601 tgaatcaatc atggcaaaag aattgaaatt tgcagaagac gcacgcgcag ctatgttacg
    12661 cggggtagat aaattagcag atacagtgaa agtaacatta ggacctaaag gccgaaatgt
    12721 cgtactagaa aaatcttacg gctctccatt gatcacaaat gatggtgtga cgatcgcaaa
    12781 agaaatcgaa ttagaagatc attttgaaaa catgggtgca aaacttgtat cagaagtagc
    12841 atcaaaaaca aatgatattg caggagacgg tacaacgaca gcaactgttc tgacacaagc
    12901 aatcgttcgc gaaggtttaa aaaacgtaac tgcaggtgct aatcctctag gcattcgtcg
    12961 cgggatcgaa ttggcaacaa aagcagcagt cgaagaattg cataatatct caactgttgt
    13021 tgattcaaaa gaagccattg cacaagtagc agctgtttct tcgggttctg ataaagttgg
    13081 acatttgatt gctgatgcaa tggaaaaagt tggaaacgac ggtgtcatca caatcgaaga
    13141 atcaaaaggg atcgaaacag aactagatgt tgtagaaggt atgcagtttg atcgtggtta
    13201 cttatcacaa tatatggtaa cagataacga caaaatggaa gctgttctag aaaacccata
    13261 tatcttgatc acagacaaaa aaatctctaa catccaagat attctgccat tgttagaaca
    13321 aatcttgcaa caatcacgtc cattgttgat tattgctgac gatgtagatg gtgaagcatt
    13381 gccaactctt gtattgaaca aaatccgtgg aacattcaac gtagtagctg taaaagctcc
    13441 tggtttcggc gatcgtcgta aagcaatgct tgaagatatc gctattttga caggtggtac
    13501 agtaattact gacgatctag gtttagaatt gaaagatgca acaatcgaaa acttaggaaa
    13561 tgcttctaaa gttgttgtag ataaagacaa tacaacgatc gtagaaggtt ctggagaaaa
    13621 agaagcaatc gaagctcgtg tgcaattgat caaaaaccaa attgctgaaa caacttctga
    13681 ttttgaccgc gaaaaattac aagaacgctt agctaaatta gcaggtggtg tagctgttgt
    13741 taaagttggt gcagctactg aaacagaatt gaaagaatta aaattacgca ttgaagatgc
    13801 attgaatgct acacgtgccg cagtagaaga aggaatggtc tcaggtggtg gtacagctct
    13861 agtgaacgtt atcagcaaag tttctgctgt agaagcagaa ggagacgtgg caacaggtat
    13921 caagatcgtt gttcgtgctt tagaagaacc aattcgtcaa atcgctgaaa acgctggtta
    13981 tgaaggatca gtgattgttg ataaattgaa gaacgtggaa ctaggcactg gtttcaatgc
    14041 tgctactgga gaatgggtaa acatggttga agcaggtatc gtagacccaa ctaaagtaac
    14101 acgttctgcc ttgcaaaatg ccgcttccgt ttctgccttg ttattaacga cagaagcagt
    14161 cgttgcagat aaaccagaac cagcagcgcc agcagctcct gcaatggatc catcaatgat
    14221 gggcggtatg atgtagtaat taagaaagaa ccctatttta acagggttct ttcttctttt
    14281 tttgttttat tttaagcaaa aggggcaaag aaggggcaaa aatatcaaag gctatttagt
    14341 ttatcaatta cttgttgttt ggctcttttt gttacatggt tataaataga cagagttgtg
    14401 tttgcatcag aatgccctac acgctccata atggctttaa gaggtacgcc taattcagat
    14461 aatagtgaaa cgtggctatg tctgaatata tgtgaggata gacttttttc taattccaac
    14521 tcttcctcta ctttatggag tatagcgtta aatgagtgca gcgcaagcgg agtgccactt
    14581 gtagatataa atatatattg atcgggatct gtgggtctac ctgcaagaat attgtcagct
    14641 atcacacttt caatcaattc ttttgcacga ttgggtaatt gcacttcacg ttgcgaataa
    14701 gtattttttg gagttgtttt tatagcatta tccattttca cagatgtgta atctaaggtc
    14761 ccattaatgg aaattttccc atcctcatag tccttcattt gcaaagctag caattcccca
    14821 tatctcaaac cagttaaata tagaaactca gctattatgc cgtgtagttt tctgcgagga
    14881 ttggagtata gctgtttcag tatttgatca atttcttctt tctccagata ttttttattc
    14941 atagaaagcc ttcttttttc ttcttccact tttttaggat ggattttaac tgctagcgca
    15001 gggtttcttt gaatgtattt tctatcgatt gcatagttta gcataacaga tagagttgtt
    15061 tttgtttgtt ttgtgtagtt cagtgagagg tcaccaaacg tatacatatc ttcaattatc
    15121 ttattaatga gtgtctcatc aatgtttcta acgatcgtat catcgcttat gtgcttagaa
    15181 acatgtttca tcatcattgg aaccttcaaa tagctagtac gtttaacatg ctgcttataa
    15241 tattcatacc attctttata cagctcacca aaagtgatat ctgatttatt gtaatcttcg
    15301 agtgcttctt taattttttt atctagaatt ttctgagctt ttttccacgc ttgtggtgaa
    15361 ttacttgtaa gtgttgtaga tttttttcgt gttttttctg tataaggatc tacatatctt
    15421 tcaataaact tgaattggcc atctttggtc tgttcaaccc acacttttaa catctcctat
    15481 catttgctat aataggcata acaaatagac ctatataggt ttgttttcta aaagcacgct
    15541 cttactctgg acggtggggc gtgtttttta tttattatac agttgcttta aaaatagctg
    15601 ctttttcaaa tgatactaaa ggagagaagt ggatttctat ttctcccttt tggtttaacg
    15661 tgaaatgagc agttacatcc atttgttttc ctggagcaac agatcccatt gtattttcgt
    15721 tggcatatgt ctctgatttt ttgtcatctg gtccatatac ttccacatct gtacctacag
    15781 ggatatctga atcgccatca ttttttacgg tataagtaat ttttactact tgtgcaggtt
    15841 ggttttcttc aaattgattt ctttcatcag ttagttctac actatttagt gtatattcag
    15901 catcaccaac ttttacagtg tcaccaatct tatagaaggt atcgcttttt tcttctttag
    15961 aagatgaagc agaggttgaa gatttagtta ctttttcgcc accattatca cttgctttat
    16021 tactatctga tccaccattt aaagcagaac caataattat aattaaaatt actgctaata
    16081 cccaaaacca tacttttttg taaaaaggtt tactaacttt atacattttt ccgtcttgac
    16141 ccataacttt ttttgccatt taaatattcc tcacttcttg ttataatata tttgcgatct
    16201 cagaaatgag gtatgagtcc gtgtgccagc acgggctttt ttaatgtttt gctgaaatcg
    16261 gtttttttaa taattcttga tgtattcata catattgcct tgcgtaagaa tattttttct
    16321 taaaatagca ttggcagaca gcataacaag tgtatctgag cttattctga atagaataat
    16381 actccataaa tttttcgaga ttaaactgag attcatcagt cagttcgttc tcaatataga
    16441 tatttaataa aattagaata gctattttat ctgcttctgt ttcaaatttt gagtgaaaag
    16501 ttgtagaagt atcgtacaaa actgaatatt caaaatgaga agcggtgaaa tgcgcaagtt
    16561 catgagataa atgaaaggct tctgcagttt cgccatatag attttcattc aaaaaaatga
    16621 ttctaggctt cggataatag aagccaggct ctttcatttc catgtaaact actttcaaat
    16681 tgtattcgct caacatttct ttcaatttca aatacataca acccatcact ccaactattc
    16741 attttcctct aaagctttag caattgcaat cgctttacgc attgtctcct tagatatttc
    16801 ttttccatca aaagaaaaaa cagtatcgtt ttctgataaa tccacatgtt taggggtttc
    16861 tctttcttct ctacctagaa ggtagtctac agagactcca aagtaatcag ctaaccgagc
    16921 taactcaata gaattaggag tttgtctttt ccaacttcct aaatatccat tcgaataccc
    16981 gaaattcatt tcgagctgtc taatggataa tcctttttct tttgctaact cctttattat
    17041 ttcgtaagta ttcattgata aatcaacctt tctgaat
//
LOCUS       DACGDM010000050        16372 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.051, whole genome shotgun sequence.
ACCESSION   DACGDM010000050 DACGDM010000000
VERSION     DACGDM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.051"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            3..551
                     /gene="hslV"
                     /locus_tag="IXR05_001780"
     CDS             3..551
                     /gene="hslV"
                     /locus_tag="IXR05_001780"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAQ4260275.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            565..1965
                     /gene="hslU"
                     /locus_tag="IXR05_001781"
     CDS             565..1965
                     /gene="hslU"
                     /locus_tag="IXR05_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAQ4260276.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            1983..2774
                     /gene="codY"
                     /locus_tag="IXR05_001782"
     CDS             1983..2774
                     /gene="codY"
                     /locus_tag="IXR05_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAQ4260277.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            2856..3731
                     /locus_tag="IXR05_001783"
     CDS             2856..3731
                     /locus_tag="IXR05_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAQ4260278.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(3863..4501)
                     /gene="plsY"
                     /locus_tag="IXR05_001784"
     CDS             complement(3863..4501)
                     /gene="plsY"
                     /locus_tag="IXR05_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAQ4260279.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            4628..5062
                     /locus_tag="IXR05_001785"
     CDS             4628..5062
                     /locus_tag="IXR05_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAQ4260280.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5228..7273
                     /gene="parE"
                     /locus_tag="IXR05_001786"
     CDS             5228..7273
                     /gene="parE"
                     /locus_tag="IXR05_001786"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAQ4260281.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            7285..9735
                     /gene="parC"
                     /locus_tag="IXR05_001787"
     CDS             7285..9735
                     /gene="parC"
                     /locus_tag="IXR05_001787"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAQ4260282.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            10012..12243
                     /gene="pflB"
                     /locus_tag="IXR05_001788"
     CDS             10012..12243
                     /gene="pflB"
                     /locus_tag="IXR05_001788"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAQ4260283.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            12487..13248
                     /gene="pflA"
                     /locus_tag="IXR05_001789"
     CDS             12487..13248
                     /gene="pflA"
                     /locus_tag="IXR05_001789"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAQ4260284.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            13333..14259
                     /locus_tag="IXR05_001790"
     CDS             13333..14259
                     /locus_tag="IXR05_001790"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAQ4260285.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            14441..15334
                     /locus_tag="IXR05_001791"
     CDS             14441..15334
                     /locus_tag="IXR05_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAQ4260286.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            15468..15593
                     /locus_tag="IXR05_001792"
     CDS             15468..15593
                     /locus_tag="IXR05_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260287.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(15727..16359)
                     /locus_tag="IXR05_001793"
     CDS             complement(15727..16359)
                     /locus_tag="IXR05_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260288.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
BASE COUNT         5814 a         2791 c         3492 g         4275 t
ORIGIN      
        1 acatggtcga atcaccattt cattcaacca ctatctgtgc cgtcgaaaaa gacgggaaat
       61 ttgctatggc tggagatggc caagtaacaa tgggtgaatc tgttgtcatg aaaggcactg
      121 caaagaaagt acgacgtatc tacaatggag aagttgttgt aggtttcgcc ggaagtgttg
      181 cagatgcgtt tactttagaa gaaaaatttg aaggcaaact aaacgaatat aacgggaatc
      241 tacaacgcgc agctgtcgaa ttagctcaag aatggcggac acagcaatct atgcaaaaac
      301 ttgaagcgat gctgatcgta atgaatgata aagaaatgct tcttgtttca ggtacaggag
      361 aagttatcac accagatgat ggtatcttag ctatcggatc aggagggaat tttgcgttgg
      421 ctgcagcccg agcaatgaaa aactatgctc aaaacgacat gagtgcgaaa gaaattgcag
      481 aaaatgcgtt aaatattgcc gcagatatct gtatctttac taatcataat attatcgtag
      541 aagaactgta agaggtgagt agatatgtat gaattaaaac aaacaccaag acaaatcgta
      601 agtgaattag atgaatatat cgtaggacag cacgcagcaa aaaaatctgt tgccgttgct
      661 ttgcgtaacc gctatcgccg tttgcagtta gatgaaaaaa tgcaacaaga tattacacca
      721 aaaaatatgc tgatgatcgg acctacaggg gtcggtaaaa cagaaatcgc acgacgtttg
      781 gcaaaaatcg tcaatgcacc atttgtcaaa gtcgaagcaa caaaatttac tgaagtcggt
      841 tatgtcggaa gagatgtaga atcaatggtt cgggatttag tagaaaatgc gatccaaatc
      901 gtagaaaaag agcagtacag ccgtgtatac acaagtgcta aaaaaaatgc agaaaaacgt
      961 ttggtaaaaa tcttggtacc tggtatcaaa aaagaacaga aacaatccac taatcaattt
     1021 gaacaaatga tgaatctttt taatgctagt cagcaaaata ccgctgaacc gcaagaagaa
     1081 gtgacagaag atattcgaat caatcgccgt acagtcttgg aacaactaca aaagggttta
     1141 ctggatagtc gtgaagtaac cattgaagtt gaagaccaaa agaaacctgc accaatgatg
     1201 aacaatggat tggagcaaat ggggatcgac ctaaatgaaa ctctaggtgc tttgacaccg
     1261 aagaaaaaag tggaacggac ggtaacagtc aaagaagctt tagagttatt gatcaaggaa
     1321 gaatcagcaa aattagtcaa ggatgctgat atccatagtg aggcaatcaa attagcggaa
     1381 gaaagtggaa ttatttttat cgatgaaatc gataagatca cttctaaatc acagcaatct
     1441 ggagaagtat ccagagaagg cgtccaaaga gacatattgc caattgtcga aggttcacaa
     1501 gtaaacacaa aatacgggat catccaaaca gatcacgtcc tattcattgc ttcaggagct
     1561 ttccatttgt ctaaaccaag tgatctaatt ccagaacttc aaggacgctt cccgatacgg
     1621 gtagaattag atgatttgac agctgaagat tttgtgaaga ttctgaccga accaaataat
     1681 gctttagtaa aacaatacgt cgcgttgatc ggtacagaaa atgtgtcagt tacgtttaca
     1741 aaagaagcaa ttgaacggat cgctcaaatc gctttcgatg tcaaccgtga cacagataat
     1801 atcggcgcac gcagactgca taccattttg gaaaaactac tagaagatct attatttgaa
     1861 gcaccagata tgcaaatggg agaaataacg atcacagaag catatgtgga tgacaaactt
     1921 ggctcaattg cggcaaatga agatttaagt cgctatattt tataaaaaat cggaggacga
     1981 caatgacaga cttgctaacg aaaacccgca agataaacac acttttgcag caaaagaata
     2041 cttttgacat gcaagcagat ttgccttacg ataaaatggc tgtcacacta ggtggtattc
     2101 ttgacagcaa cacctatatc ataggaagtg acggagtatt actaggttat aatgaacgtc
     2161 acgatgtgaa caatgaacga atcaaaacaa tgtttgttga gaaacaattt cctgaatctt
     2221 atactgatac agtggcacag ttgatgaaaa ctgaagctaa tatcccaatt actagtgata
     2281 ttactgcatt tccggtagag tcaagagaga aatatccatt tggtctgacg actgtcgttc
     2341 cgatctttgg agctggcgaa cgtttgggta cgattatctt atctcgtatg gaacaatcgt
     2401 ttgcagatga cgatctagtc ttagcagaat atggagctac ggttgtcggt atgcagatcc
     2461 tttatcagaa gtctcgaagc atcgaagcag atgtacggag tgcaacggct gtccaaatgg
     2521 caatcaacac attatcttat agcgaattga aggctgtaca agctatcttt gaagcattgg
     2581 atggagatga aggtcgtctg actgcttcta atattgccga tagtatcggc atcactcgtt
     2641 ctgtgatcgt caatgcttta cgaaaattgg aatcagctgg aatcattgaa tctcgttcgt
     2701 taggcatgaa gggaacttat ttaaaagtat tgaattcccg ttttaaagac gagttagcaa
     2761 aacacagtta ttagaagtaa ggggactggg gcagatagaa atgtttgttc cagccttccc
     2821 attttaaaaa gtaagtcgaa gttggaggaa tggcaatgac tgttattatt caaaatgacc
     2881 agctgatcgc cgaaatcgct gaacacggtg cggaattgat cagtctgaaa tcaaaagaac
     2941 atggtttaga gtatatctgg caaggtgatc cagcgtattg gggcagacat gcaccggttt
     3001 tattcccttt tgttggacgt ttaaaagatg atcagtatgt ttatcaaggg aaaacatatc
     3061 aaatggggca acacggattt gctcgggata tggattttga agtcattgaa catggacaag
     3121 aaatggctag tttcatctta aggagtacgc cggagacatt agaaaagtat ccatttgatt
     3181 ttgaattagt gatcagctat gaattaggag gagacggcat cacggttcat tatcaagtgg
     3241 caaataccgg tgaaaaagaa atgttctttt ctatcggtgg acatcctgct ttcaatgtac
     3301 ctcttgaaga aggattgtca tttgaagatt tctatctggc attttctcca ttgaaatcaa
     3361 gattacgcct accattgaaa ggcccattca tcgatatgga tcaaaagacg ttaggtcaga
     3421 caaatacgaa tctggctttg aatcgtgaac tttttgagca agatgccttg gtttttgaaa
     3481 caaggggtct aaatgcgtac gccattcgaa gtgaaaaatc ttcccatagc gtaactttaa
     3541 gctataaaga tatgccttat gtagggatct ggtctcctta tccaaaagaa gcgcctttcg
     3601 tttgtatcga accgtggtgc ggaatcgctg acacggtgaa cagtagtgga aacttgatgg
     3661 aaaaagtagg gatcaatcaa ctaggtgccc atgaaatctt caagacaaaa tattccatca
     3721 cagtgaagta agaggttgtg accgagaagt tagcagggaa caccgtttac caaggtgtgt
     3781 aaaaaagcta tcctgtaagt aataagggag tgtgacatcg atttgtcaca ctcccgtttt
     3841 atctctttgg aatgaaaaag tatcaggatt ttttcttgct gctattcaaa ccaaacggga
     3901 ttcgactttc agtatggttt ctgatacgct tgatattgtc tttatgccga taaaagataa
     3961 aggaagaaac taaaaaggca atgatcgtca gtaaccaatt gggcttagcc aaaatcacag
     4021 gagctacata aggaaggacg atcgtagata aagtgatcaa tactgcactg atcatactgc
     4081 tcaaactcac catacttgta caaaataaac taacgataaa gatgatacaa gaataaacaa
     4141 aaaatacagg attaaatcct aaaagcattc ctgcacttgt cgcaacagct tttcctcctt
     4201 tgaacccagc aaaaatcgga aatgtatggc caagaatggc gcatacccca aaccaaagag
     4261 ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt agccaatgta ccttttaaaa
     4321 tatccataag caggacaaca atcccggctg ttttgcctaa tacacgaaat gtattggtcg
     4381 ttccagtatt accgctcccg tgttgtcgga tatctttttt gaaaaacaat ttgccaatcc
     4441 agacaccgga aggaatagaa cctaaaagat atgctaaaat aagtaataag atcaatttca
     4501 ttttttaccc tctttcaagt tgaaaactat cctttatttt agcatgaata ggtaacagga
     4561 acaattgaaa aaatgaaaga tacaagtata atagatggaa taaaaagaaa agcaaggggt
     4621 ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt ttcaactatt tggaagaagc
     4681 aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa cgaacaagtt acatggttgc
     4741 acaggtattg caagacaatg gatataaaat cataccagta aatccattat tggctggtga
     4801 agaaattcta ggcgagaaag tctatgcgaa tttgacagaa atcgatgatc caatcgatat
     4861 cgtagatgta tttagacgga gtgaattttt acctgaaata gcaggtgatt ttttgaaaac
     4921 tgatgctaaa gtgttctggg cacaattagg gattgaaaac aaagaagcag ctgagatgct
     4981 aagaaaagca ggacgtacag atatcgtaat ggatcgttgt attaagattg aacttggtaa
     5041 gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga gatgatcgat agaggggaat
     5101 gtcgaaaaag cggttaggag ataattaaaa ttgatttctc gtctaccctc ttttttttca
     5161 cgaccttttc tagtatgata atcgtggtgc ggttttgccg caaagtatta ttgaaggagc
     5221 gtttgccttg gcaaaaaaag taaacaacga atacaatgac tcgtccatcc aagtattgga
     5281 aggattagag gcagttagaa aaagaccagg gatgtacatt ggatccactg acagccgagg
     5341 cttgcatcat ttagtctatg aaatcgtcga taatgcagtt gacgaagcat tatcaggtta
     5401 tggcagtgag attgatgtga ccatccatga agacaatagt ataactgttg cagatagcgg
     5461 acgtgggatg cctgtaggaa tgcatgcttc cggaatacca acagttgaag tgatttttac
     5521 tgtgctgcat gctggcggaa agtttggtca aggagggtac aaaacttctg gtggactgca
     5581 cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg ctaattgtaa cgatcgttag
     5641 agatggcgta gagtatcagc agaaatttaa aaacggcggt aaacctgacg gtactttgaa
     5701 aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc cattttttac cagatgatac
     5761 aatattcagt acaacgaaat tttcatatga aattttagcc gaacggttaa gagaatctgc
     5821 ctttcttcta aaaggcgtta aaatctctct ttctgatctt cgtggagaag aaccagtcaa
     5881 ggaaattttt cattacgaag aaggaatcaa agaatttgtt gattatctga atgaagaaaa
     5941 agatacattg acaccagttg tttatttttc aggagaaaaa gaaggtatcg aagtagaggt
     6001 cgcttatcaa tacaatgacg gttattcaga aaatgtttta tcttttgtca ataacgttcg
     6061 gacaaaagat gggggaaccc atgaagctgg tatgaaagcg gcgatgacga aatcttataa
     6121 tgaatatgcg agaaaagttg gtttgctgaa agaacgggac aagaatctgg aaggtagtga
     6181 tttcagagaa gggttagctg ctgtactttc tatccgtgta cctgaaaatc ttctgcaatt
     6241 tgaagggcaa acaaaagaaa aacttggtac gccagttgct cgtaccgtag tagataacgt
     6301 catcagtgaa caaatgggct tttatttgca ggaaaatagc gaaatgagcc agatgttggt
     6361 ccgtaaagca atcaaagcca gagaagcgag agaagcagca cgtaaagcca gagaagaaag
     6421 ccgaaatggg aagaagcgta aaaaaggcga atctcttctt tcaggaaaat tgacacccgc
     6481 acaatcccga aaccctaaga aaaatgaatt gtatttagtc gaaggggatt ctgctggcgg
     6541 atctgctaaa caaggaagag acagaaagtt ccaagcaatt ctacctttac gaggaaaagt
     6601 catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa aatgaagaaa tcaatacgat
     6661 gatctatacg attggtgcag gagtcggtcc tgagttttct atcgaagact gtaattacga
     6721 caaagtaatc atcatgaccg atgcggatac agacggcgcc catattcaag tattactgct
     6781 tactttcttt tatcgttata tgaaaccgct gattgaagct gggaaagtat atatcgcgtt
     6841 accgccttta tataaagtat ccaaaggaca aggaaagaag caagtcattg aatatgcgtg
     6901 gacagatgac gaattggcag caatgattaa aaaagtcggc aaaggatata tgctgcagcg
     6961 atataaagga cttggagaga tgaatgcgga acaattgtgg gaaacaacga tggatccgac
     7021 ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg caagctgaac gtcgagtaac
     7081 cacactgatg ggtgacaaag tagaacctcg aagaaaatgg atcgaaaatc acgtgcaatt
     7141 tacgctcgaa gaagatggca gtatcttaga taaaaaagag gatactgaaa tctctccttc
     7201 agtttctaat gatttattag atgaagaacg agcagataaa aatgaaaaca atcagttatt
     7261 tgaagtagaa taggaggtca cctgatggaa aatcgacaag aagtacaaga attaacttta
     7321 gaagaagtga tgggtgaccg cttcggacgt tattccaaat atattatcca agaacgtgca
     7381 ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc ggatattatt tgccatgaac
     7441 aaagatggca atacgtatga caaaggattc cgtaaatcag caaaatctgt cggaaatatc
     7501 atggggaatt atcatcctca tggtgacatc agtatttatg aagcgatggt ccgcatgagc
     7561 caagactgga agttgcggga agtactgatc gaaatgcacg ggaataacgg gagtatggac
     7621 ggtgatccac ctgctgcgat gcgttatact gaagccagat tatccaagtt aagtggagag
     7681 atgctagcag atatcgagaa agaaacagtc gatctcgtgt ggaattttga tgatacagaa
     7741 aaagaaccaa cagtccttcc agctcgatac ccaaaccttc tcgtcaatgg atcgacaggt
     7801 atatctgctg gatatgcaac agaaatcccg actcataact tagctgaagt gatcgatggc
     7861 acaatctata tgatcgatca tccacaagcg agccttgaaa aattgatgga atatattcct
     7921 ggacctgact ttccaacagg agggatcttg caaggaaaag atgaaatcaa aaaagcttat
     7981 gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa agatagaggc aatgaagggt
     8041 aataaacagc aaatcgtgat cacagaaatc ccatatgaag taaataaagc gaccttggtg
     8101 aaaaaaatgg atgagatccg tttgaataag aaaatcgatg gaatagctga agtacgagat
     8161 gaaagtgata gaacaggtct gcaaattgtc gtcgaattga aaaaagacgc caatgctcaa
     8221 ggaattttga attatttgtt caaaaacact gagctacaga tcaattacaa tttcaatatg
     8281 gtcgctatcg accatatgac tccgcatcaa gttggactga aagacatttt aagaagttat
     8341 atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat tcgatttagc caaagctcaa
     8401 aaaagacagc atatcgtaga aggattgatg aaagctttat cgattctgga tgaagtaatc
     8461 gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa agaatttagt cgacgtcttt
     8521 caatttacag aagaacaagc agaagcaatt gtcacattgc aattataccg tttgacgaac
     8581 acggatatca cagagcttca aaaggaatcc gaaagcttga ttgcgcaaat cacagagttg
     8641 aataaaatcc tttcaaatga caaagagctt ttctctgtta tgaaaaaaga attgcgagaa
     8701 gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg aagacgaaat cgaagaaatc
     8761 aaaattgata cgcaagtctt agtggcacaa gaagacgtaa ttgtcagtgt gacgcgagaa
     8821 ggctatgtga agcgaacaag ccttcgttct tatagtgctt ccaaaccaga agaaatcggg
     8881 atgcgagaag gcgactactt gctatactca ggtgaattga gtacattgga ccatgttctt
     8941 ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc atgaactacc cgatttgaaa
     9001 tggaaagatg ctggtgagca catttctcaa acaatctcca atctgtctgt agacgaatcg
     9061 attttagctg ttttcccata tcaaaaaatt caagcagaga aaacatttgt attcatcagc
     9121 aagaatggat tgatcaagca aacacgaatg acagagttcg aaccatggcg cacctataag
     9181 agccgtccgc tcagctgtat gaagctaaag gcggaagaag atgaactgat tgctgtgtat
     9241 ctgaaagaag atcagccagg cttagatgtt ttcttagtaa cgcatcaagg aatgggtttg
     9301 cgctatcctt taacagatgt tcccgttgtt ggagcaaagg cagctggagt gaagtctatg
     9361 aatttgaaag atggagatag gattatcaac gggctgcttg tgttagcaga aggtgatacg
     9421 ccgatcgtaa tcgttactca gcgaggagct gttaaacgca tgcttgctca agaaatcagc
     9481 caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg agctgaaaaa aaatccgcac
     9541 cgtattatct atatgtcgga aggaagatca aaagaaataa ccttgatgaa tcaaaaaggg
     9601 cagcagttaa cgattgaccc aactgatttc cctataggtg atcgaacatc gaatggatca
     9661 tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag ttatcgatgc tcctgagatt
     9721 ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga cgccatctgt attaatacag
     9781 gtggcgtctc tttttcattc atttttaata aatccttata cgtttgcaaa aaaagatgaa
     9841 agtgttcaca atgcttaaat gttggtatgt caacgttgat ttaaatatat gtaaataaaa
     9901 cataaaaatt gttaaataaa aaacaagaaa acccttgcaa agatagggtg ctgtgttata
     9961 ctaatcacgt aaaaactgtt acataaaaca gaaatttagg aggtccatac aatggagcaa
    10021 tggaatggat ttaaaggtac caaatggaaa gaaggcgtag acactagaga ctttattcaa
    10081 aataactaca ctgaatatcg cggtgatgac agctttttgg aaggcccaac agaagcaaca
    10141 gaaaaattat gggatgaatt gcaaaagtta aatgatatcc aattcgagcg taacggtgtc
    10201 tatgatatgg acacagaaat cgtatcaact attacttcac acgatgcagg ctatttggat
    10261 aaagatttgg aaaaaatcgt cggtctacag acagacaaac ctttgaaaca agcattcatg
    10321 ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa gcaatggcta tacaccaaac
    10381 gatgaattga cacatatttt cactgactgg cgcaaaacac ataatcaagg tgtatttgac
    10441 gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa tcattacagg gcttccagac
    10501 gcttacggtc gcggacgtat catcggtgac tatcgtcgtg tggcattgta tggaatcgac
    10561 tatttgatgg aacaaaagaa aaaagatcat gatatgactg gttatcatac aatgagtgaa
    10621 gaagtgattc gtttacgtga agaaatcact gaacaatatc gtgcattagc gcaaatgaaa
    10681 gaaatggctg cgaaatatgg ctatgatatt tctaaaccag ctgcaaatgc aaaagaagct
    10741 gtccaatggc tatacttcgg atatttagca gcaatcaaat cacaaaatgg tgctgcgatg
    10801 tcaatcggac gtatctcagc attccttgat atctatatcc aacgtgattt ggataatgga
    10861 gtaatcacag aaaaagaagc acaagaattg atcgaccact tagtaatgaa attacgtatg
    10921 gtcaaattcg cgcgtacacc tgaatataac caattattct caggattccc tatctgggct
    10981 actttatcca ttgcaggtat gggattagat ggtcgttcat tagttacaaa gaatgatttc
    11041 cgtctgcttc atacattaac aaatatggga ccttcaccag aaccaaactt gactgttttg
    11101 tattctgaac accttccaga aggattcaga acatatgcta gcagaatcgc tatcgaaagt
    11161 tcttcgattc aattcgaaaa tgataatcag cttcgtgaac aatggggttc tgatgattgt
    11221 gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag acatgcaatt ctttggcgct
    11281 cgtgctaact tggctaaaac actattatat gccatcaatg gcggagtcga tgaagtgact
    11341 ggcgcccaag ttggaccaga atatcgtcca atcacatcag aaatactaga ctttgaagaa
    11401 gtgaaacata acttcatgaa tatgatggat tggttagcag aactatatgt caatacgttg
    11461 aacatcattc attatatgca tgataaatat tcttatgaag cagctcagct ggctttgatg
    11521 gattctgact tgcaacgcac atttgctaca ggtattgctg ggatctctca tgcggcagac
    11581 agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc gtaatgaaaa aggaatagca
    11641 gttgattttg aagtggatgg cgacttccct aaatacggaa atgatgatga ccgtgcagat
    11701 gaattagttt catggatctt ggaatacttc atgggacaaa tcaaacgtca taaaacttac
    11761 cgcaactcaa aaccaacaac ttcattattg acgattactt caaatgttgt ttacggtaaa
    11821 aatacaggaa atactcctga tggccgtgaa gctggaaaac cacttgcgcc aggagcaaat
    11881 ccaagttaca atgcggaaca aagtgggtta ttagctagcc tgaactcaac agctaaaatg
    11941 aattacggct gtgcattgga tggaatttca aatacccaaa caatcaatcc ttcaggtctt
    12001 ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg tcttagatgg atacttctca
    12061 aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg atttattgcg tgatgcaatg
    12121 gaaaatccaa tgaaatatcc gaacttgacg atccgggtat ctggttatgc agttaaattc
    12181 cgtgacttga caagagaaca acaattagat gtcttgatga gaacttcaca cgacagaatg
    12241 taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa aggacgttga atagccatcg
    12301 catcaaaatc gaataatcag tatgcttatt tgaaagaaac gatttacagg ggcaggactt
    12361 gtatgttccg tccctgtaaa ttttacacat aacgaagcgg caattgcgaa aaattttgtt
    12421 cagaaagctt cgcttcgaca gctaacttgt acttaaaatg aaatcaaaga aaagatgtga
    12481 acttaaatgg aagaaaaaac aatcggctat gttcattcta tcgaaacttt cggttcagta
    12541 gacggacctg gactgcgctt tgtcgtgttt atgcaaggat gccgcatgcg ttgccaattt
    12601 tgtcacaatc cagatacttg gaatattggc ggagggaaag aatacacagc agatgaactt
    12661 ttagataaag cagaacgctt cagaccttac tggggagata aaggtggtat tactgttagt
    12721 ggtggagaac ctctattgca gatcgatttt ttgatcgaac tatttaaaaa agcaaaagag
    12781 cggaagatgc atactacatt ggatacatgc ggaaaacctt ttacgtatga agaacctttc
    12841 ttttcacgtt ttcaagaatt gatgaagtat acagatttac tgttatttga catcaaacac
    12901 atcgataatg aagagcataa aaaactaacg cattgggaca atgaaaatat tttagaaatg
    12961 gctcaatatt tgtcaaaaat caacaaaccg gtttggattc gccatgtact agttcctgag
    13021 cgaagtgatt atgatgaata tttgatccga ctagacaact ttattcaaac cttgtcaaat
    13081 gtagacagag tagagattct tccttatcat acgatgggaa aatacaagtg ggaaacactt
    13141 ggtttgaaat atccattaga agggatcgaa ccacctacaa aagaacgtgt cgaaaatgct
    13201 aaacgattgc ttcatacaga agagtataca aaatatttaa cgcgataggt cgcatcggaa
    13261 agaagataag tattgcttct ttccgttttt ttgctattat taaataggag aaatcacaaa
    13321 ggagcgaatg acatgtcaaa aattttagtt tttggtcacc aaaatccaga tacagatgca
    13381 atcggggcag ccattgcgtt ttcacacttg caaaatgaat taggtaaaga aacagaagca
    13441 gttgctctag gtacacctaa tgaagaaaca caatacgcat tagaccactt tcagctatct
    13501 gcaccacgag tagtagagtc agctaaagca gaaaatgcag atgtcatgct tgtggatcat
    13561 aatgaattcc aacaaagtat ttcagatatc agcgaagtaa atattttagc tgtagtagac
    13621 caccatcgta ttgcaaactt tgaaacagct aatccattgt actatcgtgc agaaccagtt
    13681 ggatgtacaa gtacgattat tttaaaacta tataaagaaa accaagtaac aattcctaaa
    13741 gaaatcgcag gaatcatgct ctcagctatc atttcagata cattgttgtt caaatcacca
    13801 acatgtacgc ctgaagatga agcagctgca aaagaacttg cagcaatcgc tgaagtcgat
    13861 ctaaacactt atggacttga aatgttgaaa gcaggaacaa atctaagtga taaatcagct
    13921 gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg gcagttccaa cgttcgtatc
    13981 gctcaagtca atacagtgga ccttaatgaa gtgatggatc gacaagcaga gctagaagca
    14041 gcaatggaag atgaaatgaa agcaaatggc tacgatctgt tcgtattagt tgtcacaaac
    14101 atcttagaca gtgattcaga attacttgtt gctggtaaag gaaaagaaaa agtagaagaa
    14161 gctttccaaa caactttgac caacaaccgt gctttgctta aaggtgtcgt ttcacgtaaa
    14221 aaacaagtcg tacctcaatt gacggctgta tttagctaat caaatggtag tatgaagcat
    14281 tcaaaatgaa tggataagcg attgatataa aaagaaacat agaacatact aaaggccgaa
    14341 gaaatggagg agaataacag tcaattatga ctcttgttct tcctcctttt tacgtaaaag
    14401 ccttttaagt aaaataaaac ggatagaaaa gagaacatat atgaactatt attcaaaaaa
    14461 taaggaaaac ttttatcaaa aactgaccga tgatccgctt ttttcttcat tgaccgatta
    14521 tctatatgaa catcgagaac aagaaacgat tctaagagaa ttgaaaaaag aattttcgca
    14581 aaataaattt tcccattttc ttgatttatt gatcgatgca ggattaatca agagggaaga
    14641 acgaagatat catttgaact ttccaatatt tgatcctaaa gattacttgc aacaagccac
    14701 ttcggctgct gaaaccatag ctgaacaatt gaagagactc tctgttgatg aacaaaaatt
    14761 agcgatggga gaagttattt gggcgtattg tttcgaagat gaacggaaag aagcgtattt
    14821 ttatggagta agaaacagcc gagagacaga attgctgagg acaactgcag gaaatgagaa
    14881 gtaccgtttt atcacacttt cctctataga acacttcccg cttactttgg ctaattactt
    14941 ttttgtacag aagaatcagc ttcctgtaac gaaggcattc aaagaattag ccgaacttat
    15001 tggagacgta aatgaatcgt acttttttga tcaaatagaa gttatcgttg acaggatacg
    15061 taagaataaa tataaaaatc gccggcctag tattttccat cagtctctac ttgtgacgaa
    15121 tactataaag gaagaagaat cattcacatt agaattacct attgtcgaaa aaaacaattt
    15181 tgagattgaa ttaccaacat tggatccttc attgacaatg gaggaaatgg cctttcttaa
    15241 acgacaaatc ttttctgagc tgagcaagaa atttataccg catgcatttt cttatatcaa
    15301 agaatatgga acagttttag tgagtaaaac ctaagagagc agtaagcaaa aattatactg
    15361 actcttgcag gaggagcctt tctcttcctt tatggttaaa agaattattt gagtattttg
    15421 cctatctacc acctattaga ttcactacat ggtctggaaa caaaggaatg caaaaaaatg
    15481 gtgagaaatg tggaatgaca aaggaagtag tgataagaaa agttagattt ttaaataatc
    15541 aatattatga ttcagtcaag tatggcattt tatgggaaga actagctgat tagattagga
    15601 agtccatttg ataatccaga atcactaaga aacgaatggc gagtcattaa taatttatcc
    15661 aatcttgggt tattctttta gattgaagtg tttaaaacta aaaaagcatt tatgaagtcg
    15721 taatagtcag gcttcaaaat gctttttatt ttgtttgttt tttctttgcc acataaatac
    15781 acctagactg acgatgaaga gcatatccaa cagatttcct gcgacttgga tcgtcgaagg
    15841 gttggtcagt ggcattaaag caaggacaaa aaaggaaaac aagctgtaaa taaaacaggt
    15901 gacaggaact aatcgaaaga agagcggaca tttcaattgg ctaaaaatga gtgaaaaaat
    15961 aaaataagta aaaatggata aaatcacgac taaaccattc atgataaaga agaaaagcgt
    16021 attgtgatta aacgaataaa aaagaattgc taaaaaagaa aacgttttaa atgcaatcaa
    16081 tacgcttgaa gcttcgttta acgtaccagg atgtcgatga aaaaaatagg caccgaaata
    16141 aacagaaaac agtaagccgc aaagagaaga caaaatcaaa aaaaacggat tttcttcggc
    16201 ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat gcactagaag gcgcatgtga
    16261 ggtcttaagg tatgaataac atagaaaaaa taagatcgtc aaagttgcaa aaaaagagcc
    16321 taaatgtaaa aaattagtgg ttctacgttg aatttccata atatctccaa at
//
LOCUS       DACGDM010000051        16163 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.052, whole genome shotgun sequence.
ACCESSION   DACGDM010000051 DACGDM010000000
VERSION     DACGDM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.052"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            226..894
                     /locus_tag="IXR05_001794"
     CDS             226..894
                     /locus_tag="IXR05_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAQ4260289.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFSLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1480)
                     /locus_tag="IXR05_001795"
     CDS             complement(1094..1480)
                     /locus_tag="IXR05_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260290.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1452..2834)
                     /locus_tag="IXR05_001796"
     CDS             complement(1452..2834)
                     /locus_tag="IXR05_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4260291.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2990..4177)
                     /locus_tag="IXR05_001797"
     CDS             complement(2990..4177)
                     /locus_tag="IXR05_001797"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAQ4260292.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4184..5215)
                     /locus_tag="IXR05_001798"
     CDS             complement(4184..5215)
                     /locus_tag="IXR05_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4260293.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVGIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5231..6685)
                     /locus_tag="IXR05_001799"
     CDS             complement(5231..6685)
                     /locus_tag="IXR05_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4260294.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEELENKLAPADTMEDELHDAVVPSH"
     gene            6860..7765
                     /locus_tag="IXR05_001800"
     CDS             6860..7765
                     /locus_tag="IXR05_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4260295.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7856..8533
                     /locus_tag="IXR05_001801"
     CDS             7856..8533
                     /locus_tag="IXR05_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4260296.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8814..9710
                     /locus_tag="IXR05_001802"
     CDS             8814..9710
                     /locus_tag="IXR05_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4260297.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9765..11135)
                     /locus_tag="IXR05_001803"
     CDS             complement(9765..11135)
                     /locus_tag="IXR05_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4260298.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11373..12119
                     /locus_tag="IXR05_001804"
     CDS             11373..12119
                     /locus_tag="IXR05_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260299.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12116..12955
                     /locus_tag="IXR05_001805"
     CDS             12116..12955
                     /locus_tag="IXR05_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4260300.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12956..13906
                     /locus_tag="IXR05_001806"
     CDS             12956..13906
                     /locus_tag="IXR05_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAQ4260301.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14047..14799
                     /locus_tag="IXR05_001807"
     CDS             14047..14799
                     /locus_tag="IXR05_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260302.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14818..15969
                     /gene="queG"
                     /locus_tag="IXR05_001808"
     CDS             14818..15969
                     /gene="queG"
                     /locus_tag="IXR05_001808"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAQ4260303.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEVYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5248 a         3017 c         3243 g         4655 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttctcttg aaaatgccaa acatgttatc ctagagaatg ctggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt ttgataccgt
     1381 tgactagttc ttccatcgca aaagcagtcc cccattttaa tccaaatggc cgatctcgat
     1441 actcgttata gtcaatgaat ttttttgctg tccgtctcat cttttccacc ttctaatcca
     1501 ctcataccac ctgcatgccc gccaacgaga gaactacgtg cgatggcgcg tcctccttgc
     1561 aagagactat gcgcatggat gattgattga aagccgtatt tttttctaat cgtatcgaca
     1621 acaaaatcaa ctttcgcttc atttatctgc ttttcaggat cttcaaaaag gttaagctgt
     1681 aaacctgtcg cgtatacgag gtcggaacag ttcacgccta cacgccgaat atcctggtag
     1741 tggtaatgct ggtggaaaat ggtcaataaa gcatctgcta gatctctgct agcatttgtc
     1801 gcttcgattt tcatttgctg gtgaaacccg gtcttgccat ttggatcaag atagcctaaa
     1861 gagtatccta cccataagct gactacttgt gtttttgctg cagatcgtct caagcgagtg
     1921 ccgacttggt cggccatttc tttgataacg atctcgattt cttctcgtct tgtataatct
     1981 ctatctagga tttgactatt tccgatactt tttgattttg gtgtatattc ttgtcccaaa
     2041 aaacttcgat cgatgcccca agcatgggca taaagctgag taccgatgac ccctagcttg
     2101 cttttcaagt gataataatc cgcgtgagct aaatcataaa cagaatgtat acccatttgt
     2161 ttcagacgtt ttgctgttcg tttgccgatt ccccaaaagt cagtgatatc tgagattttc
     2221 cataactttt ctggtacatc ttcataacgc cattcagcaa acatttgctt tccgtctttt
     2281 gagccattgt ctaaggctag tttagcaagt agcgggttat cgccaattcc tatagtcgtg
     2341 tagattccgg tctgctcaaa cacatcttta tggatcagtt tagccatgtc gtacgcattt
     2401 gttttaccaa agagtgccat gctatttgtt acatcaagga agctttcatc gacggaatag
     2461 acatgatggt tcgcttcgtc tgcatatttt ttatagatag aattgatttc tctgttcttt
     2521 tccatataat aggccatcct tggggcaaca atatataaat cacttggata ggggaaggga
     2581 agatctctgg cacggctgat attggtgatg ccgtaagctt tttttgctgc aggactggaa
     2641 gccaagatta atccgctacc ccgtgtttct gtcgaatcgg acggatagga catgactact
     2701 aatttagttg taaggggatc aagatccttt tcaacgcact ctacggaggc gtaaaaagat
     2761 ttgcagtcaa tacataaaat atctcttgaa ggttcttttt cataaacaaa taccggattt
     2821 tgattcgccc acataacaat cacctcttca acacaattag aacacacgtt ctctttccgt
     2881 gtcaataaaa aacagcaatt ttcaaatacg agcaaaaggc tcacatttgg aaattgctga
     2941 gaggttattt ttatctattt gtttttagct gagatcgttg atttttttat caaacatgaa
     3001 cagcttctgg atcgatcttt gttgtcccat ttccaatgtg tgcaacataa aattccggag
     3061 catagccgac aactttcatg tattcatcat agacattgtt tttgaaggca ggtatatttt
     3121 cttctttgac aagagcaatc gcacagccac caaatccagc tcctgtcatt cgtgcaccta
     3181 agacaccttc ttgtttttga gcagcatcta ctagtgtatc taattcgatc ccagttactt
     3241 cataatcata gcgaagagag tggtgagaat catttaacag ttgaccaaat gcttctaagt
     3301 tcccagcttc taattcagct tttgccttca aagtccgctg attttcagaa acggcatggc
     3361 gagctctgcg tatcaatgta tcatcgccga tttggtcaat agttgattca aattcttctt
     3421 catctaagtc tcctaaagaa gagataggca aagttttttg caaacgtgcc aaggcttctt
     3481 cgcattcgct acggcgttca ttgtattttg aatctgccaa ttcccgccgc ttattcgtat
     3541 tcatgatgac gattgcataa ccatctagtt tcactggaac catttcgtat ttcagcgtat
     3601 ttgtatctaa taagattgca tgatctagct caccgaagcc gatggcaaac tgatccatga
     3661 tacctgaatt gacaccgatg aattcatttt ctactttttt acctgtttgg actagttcca
     3721 agcgatctgt ttttaaatca aacagatctt ctaatacaac acctactaat aattctaatg
     3781 aagcgctact ggaaagtcct gcaccattag ggattgttcc ttccactaac aactcaaacc
     3841 catgatcgat tgagtgtcca gcttctttta atttaaggac cattcctttt acgtaatttg
     3901 cccagtttgc ttttttatca tattctagct catctaaagt aaaactaatg acaccgatat
     3961 cgtcaaagtt tgtggaataa actaatattt tattatcgtc tcgaggtgct gctacacctt
     4021 gcgttccata agtgatggaa gcggggaaga catggcctcc attgtaatct gtgtgttcac
     4081 caatcaaatt gatgcgtcct ggtgagaagt attgtgtagt ttttttaggt ccgaatgttt
     4141 cggcaaattt tgtgtttaag cttcttttga tttccatgat gagttattcc tttcttgttt
     4201 tgattttgaa ttctgtcact gtttcaaata ctgatccagc ttttaaatga atcgaaccaa
     4261 atgctgagaa gcgctctgca cctggagctg tttgagtctc aaatgtgatg ccaccgtgat
     4321 gtgccagttt tcggttgcgc atttctggtg tttctgtgcc gaaatttgca gtgaaaataa
     4381 ccacactaga agcatctgta gcaataccta cttggattct tttatcgggg ctagtcaagc
     4441 gagcggcttc tttacccaag ccggtttctt ttaagaaaaa tggatgatcg attccgtcaa
     4501 caagattttt ttgatccaaa tcactagcaa aaacggacgc taatttttta ggtatttgaa
     4561 aatcgaaagc acttcctgca gcattttctt ttacccctat aggaatacta tctgttcgca
     4621 aaggagcata agcttcgcta ttgagccaaa gctcatgttg atcgattgac tgagaagcat
     4681 ctcccgtcaa gttgaagtaa acatgatttg tcggattgaa taaagtatct tggtcactgg
     4741 tgccgcgaga ggtcactcgc cagatattat cttttgtcaa agtatagcgg atttccacat
     4801 ccattgtacc tggaaaacca tgttctccgt cgggacttgt agtagtaaaa atgacagaag
     4861 cttcattttc gccattcaaa atgacataag accatttttt taattcaaat ccaggagcac
     4921 caccatgcag attatgtcca gtttttggat ctgtggctaa ttggtaagtt tttccattga
     4981 gagaaaagcg gccattttcg attctccctg cggtgcgacc gatagaagca ccgatatacg
     5041 gatctttttc gatatattct tcagcggtgt caaatcccaa aactaattct cgatcatttg
     5101 attttaaact gacgattcta gcacctaaat cagagataga aagtgctagc ttgtttttgt
     5161 tctccaaggt tatcaagtga taaccttggc caaaatcttt ttctgtaatc ttcattttca
     5221 agatcctttc ttaatgggaa ggaactactg catcgtgaag ttcatcttcc attgtatcag
     5281 ctggagccaa tttgttttcc aattcctcaa cgatttgtgc atgttttttc tctgtcaatg
     5341 taatcttcca agcaaaaata atagcggaga aaatcatcaa agcagcagga gcatagaatg
     5401 cataagcttt gaaagtcgtt acgccatgag cagtgatatc agcagcagta gcattaccag
     5461 tcatcccaga agcgatagcg acaaacccta cgatcccgtt agacaaagca ccagcgattt
     5521 tatctagtaa agggcgaatt gatagagtaa cagcttcgtt acggatacca tttttccatt
     5581 gaccatattc aacagagtct gtgatcgtca tcaaagcgga taagaaaatc aattgttgag
     5641 ggaagtagaa caatactagc ccgatgataa cgattggcaa acttgaacct gcgatcgtaa
     5701 agaaaaagta agaagaaatc atcattgcga tccctccaag gtaaacgtag cgacgagaga
     5761 tgacgcgtgt aagcattggg aatagtggaa cagctactaa accaagtaag gcagcaacta
     5821 gaccaacgat ccaaaattca gttggttggc caagtacata tttgaagaag tagaataata
     5881 cggcagttgt tgctacattg gcaatcgcat aagcgatata agcaagggca agccacatca
     5941 actgatcatt ttgagcaact gctttgaaca catctttgat cccagctttt tcattttgct
     6001 gacggatcgc agtatcgact tcttttgtgc ccaaggcagt gataatcgca gtaccgcctg
     6061 aaataacagc agcaatcaca ccgaaccaga accagcctga agcgccttca atatgtttat
     6121 gagtaacaag ataggtaaag aaagtaacga tagggacaac gactagagta gtaccatttg
     6181 cacctagaga agagccgaaa cgagcaaacg tagcaaattt ttcacgttcc tttgtttccg
     6241 tactcaaagc tggaatcatt gaccaaaaag cgatatcctt aaatgaataa aaactatcca
     6301 ataagatgaa aacgattgca aataatatga taaataaagt cgtattatga gtagctaagc
     6361 caaagaaatt ggtaaagatt gctaccaaga gtacggaact aacaacgccg ccgataacta
     6421 accatggttt gaatttaccg tattttgtac gagtattatc gatgatgcca ccaatcaaag
     6481 gatcaaaaat aatttcaact aagcggatac ctacaactaa gcttgtaact gtagcaatca
     6541 tttttgcatt cgttgcctta tctgttcctg cgaacatctg gcttgtcacg aataccataa
     6601 aataagtgct taatgtaaca tagaatgtgt cgtgtccaaa agcgcctaaa gcgtaggaca
     6661 cacgttggat cattttgctt ttcataatct gtattcctct cctgttcaat atataatact
     6721 aagtaaaccg gttacaacga ataacaaaga tcttttaatg acttaaactt aacaagaaat
     6781 cgcttccttt ttaatatatt tctgtgactt ttatttaact ttttgttgca ttatactaaa
     6841 ggagtaagga gggatagacg tggagcaatc gattttttta aaaaaggaac atcaacaagt
     6901 agaaaaagaa ttgtattttg atttttgtgg tttctctaaa acgatgccgt ttcattcttt
     6961 tggtcctgct attcgcaatg attacatcct gcatgtcgtg atggaaggca aaggatctta
     7021 tcatgtgaaa aatcaacaat tccaattgaa aaaaggtgat ctgttcttga ttcgtccagg
     7081 agactcgacg ttttacttat cagatggaga agatccgtgg atgtattgct ggctttcatt
     7141 tggtgggagt gctgcagaag aaatcattcg gcagtcgctt ttcagagaag accaatacac
     7201 gatggtctct tctgacatac aaaaatatat cgacattatt ttagaatgca tgaaagatac
     7261 ggaagaaacc ttggaaaatg aattacagtt aacagcatta acctaccgtt ttttatcagt
     7321 ccttttaaaa gatggcggaa aggtcagcgg tggtgtacaa aaggttcatt cctctttagc
     7381 tgttgaaaca gtcaaataca tcgaggcaca ttatgctgaa aaattgtctg ttgaggaaat
     7441 cgcccagcat ttagcggtca atcggagcca tttgtcgcga gtattcaaaa atcatatggg
     7501 taccagtatc aaggaatatt tgatcggggt acggatcaat cgaggggcgt ttcttctttc
     7561 tctgacggat gaatccgtgg aaagtattgc ctatcaagta gggttcaata gtctagtcgt
     7621 atttagccga atgttcaaaa agagtaccgg agaaacggct acgaactatc gtaaacgtat
     7681 gaaaaacgaa aattttaaga atattgcttt ggataccttg aaaaaacagt tggaaaaaca
     7741 aaccgcagtt tcttggacaa cctgattagt ctggttaaaa tgacaagcat cggcaaaaga
     7801 aacttgtggc ggttatgcta cactgtaaag cgaagactaa aaaggaggaa aagggatgcg
     7861 tacacttatc atcattagcc atccaacgat cgaagaatct ttaaatcagc aatttttcaa
     7921 agaagcttct gctggtttac cagctacttg gcatcatttg gaatcaagtt atccagacgg
     7981 aaaaatagat atagagactg aactacagct cttggcccag catgatcgga tcattttcca
     8041 gtttccgttt tactggtata gttctcctgc tcatttaaaa atttggcaag ataatgtctt
     8101 ggaacgagca gcacatgtat taaaagggaa agaactagga atcgtattga caacaggtgt
     8161 ggcggaaaaa gaataccaag ctggaggaaa agaagaatat acgatttccg aatttttgag
     8221 gccgtatcag cgaatcgcaa ataaattcca tatgacctat cttccgccat tcgttttagc
     8281 acaatttatg tatttatccc aggaaaaacg ttgggagaag ctaattgctt atcagcagta
     8341 tctctcattg gaaggcaaac catcgctgac tcagcggatt gactggttta ttcaaagagt
     8401 acaggaaaat cagaaaatgc aggaagaaga atctgaaaaa caagcatata tcgtagaagc
     8461 actgactgag gcaaaagagc agatcgaaga cttgaccttt acactgcaag aaatgaaagg
     8521 aacttcatta tgacaaatga ttggctgatc caacaattag atgaattaag cgaaaaatca
     8581 gaatatcaag accgtgcgct cttatatgaa ataaagaaac tgatggctga gatagacgaa
     8641 cgaacaatgc agctgcaagg agaaatcgac ggacaatctt ggaatcatct caactggtga
     8701 aattttctta taaataacaa agataaaaat gtgcacagcg acaattattt gctacaataa
     8761 gaatatgaag cgtttgataa cgctattata cataaaaatt ggtggtgaaa aaaatgtatg
     8821 atgaaaatga gtggggagaa aatgttcgga tgacccgaag aagacagcaa aaacaggcag
     8881 ctcgtaagcg gatgatcatg attggggcag cagttgccgt gtttttgatc atagcaggag
     8941 gagttgcggg tctatatttt catggaaaaa attcgtcaga agcgaaaagt acgaccataa
     9001 cggaaacaac gacaaagaaa acagagacga aacaaacaag tgagtcatca actaaaacaa
     9061 aagagacaca aacttctgaa gaaaaaacag caaatggttt gccagagcaa cttcaagcaa
     9121 tcgtaaatga ttattcgaaa aagatcgaag aaaagacgcc tgcattgatt gaagaatacc
     9181 agacagaaat tcagggaaat caagagggaa tagctggttt atcagcagtt gctaaccaaa
     9241 aagcacgtga gcttcaagca atctccgacg aagggatcag aaaattacgt gcagcgtatc
     9301 aggcagcaga aaataaagac ggtgtagact tagatacttt gatcaatcaa ttatcggcta
     9361 attatacgaa tcatgtcgct aagatttccg atatttattt gcagactagc gcctctcttc
     9421 aagcagagtc aacaagcaca caagacacaa catcttctga ttctgagaca gcagagtcgg
     9481 tagaagcttc tgaaatgcaa gctcgaacaa cacaagacac aacagattcc tctgaaacta
     9541 ataccaacag cgcgacttca caggctgcga caaccgtagt tttggaagga gaaggtccaa
     9601 atcaaatagc cgaacgaact ggcgtaccag tagaaacgat cttgtcgctg aatgggatga
     9661 gcatggagaa ttatttcctg actcccggtg agacgctaaa attgaattga taaaagcaat
     9721 aaaaaagaac gaagcttcca ctaaggtgaa gcttcgttct ttttttattt tccggttctt
     9781 ttttcgcgta caaagtaatg gatcgtcatg taaagcaaga aaacgagtcc aataatcaat
     9841 gagattctcg tttcaggatt gataaacatg aaaatcaata cgatagctaa aaaagcaagt
     9901 gtcacataat tcgtataagg agatagtggc attttaaaag gatgatcatg cattttatct
     9961 gcgtgcttct ttttgaagcg aatctcgctg atcaaaatca ctacccaagg aaccatacca
    10021 ggcaaaatac ttgagctgta tacgaaaacg aaaatatttt ctgactggtt gatgaacatt
    10081 ggtagaagat aatttaagat cagaccaatt aagattccac ctgagattgc tacgacagga
    10141 taaaaaggcg caccgtgacg agatagtttc agaaattttt tagacatctt tccatttatg
    10201 gcaagtgtat agaccatacg acttgcgctg aaaatccctg aattgcaacc tgataatgcc
    10261 gctgtaatca cgacaaaatt aatcagtcct gcagcaaatg taatgccgac tttagaaaaa
    10321 gtttgtacaa aaggtgaacc aatctcactc aattgattcc acggatagat actcacaatg
    10381 ataaaaatag caccaatata aaaaatcaag attcgaccga tagtggactg gacagcttca
    10441 atgatcgtct ttttaggatt ctctgcttca ccagcagtca ttccgatcag ttcgattcct
    10501 tgataggaag caacaacgat cgataatgca aagaaaaatc ctttgacgcc tccagtgaag
    10561 aatccaccat ttttccaaag atttgaaatc cctactgcct gaccatgatt accaaatcca
    10621 aataagatta ccccaagacc tgcaatgatc atcaaaatga tcgttatgac tttgatgatc
    10681 gaaaaccaaa attctaattc gccaaacgcc ttgacagaaa taagatttgc cagcataaga
    10741 aacaagacga caatgattcc gggaataatt gccggcaaat caggccacca ataattcata
    10801 taagatccta cagcaatcac ttcacttatt cctacgacaa tatattgaaa aatattactc
    10861 caagcggtca agtagccagc cacaggatgg atgtactcgc tcgcgtaatt tgcaaaagaa
    10921 ccagtcgaag gatcaacgta aagcatttcg cctaaagcac gcataatcaa atacaaaaag
    10981 aatcctgcaa tcgcataggc tcccatcact gagggccctg tccaacgtat ggttgaggag
    11041 gcacccataa acagaccgac accgatcgtt ccacctagtg cgatcatttg gatatgacgg
    11101 gcactaagac ttcgagttaa cttttcttct tccatacaaa aactcctttc gttgttgagt
    11161 caacaagaaa aaataatcaa acgtttcaac acatgttttt cattattagg ttagccttat
    11221 tgaactcttg atgtgattct acagaaaatt ttcataaaat gcgaggaaaa ttcgaaaaaa
    11281 actttttcat cattctactt gaaaatgctt tccattttag ttaaactata tttaaataaa
    11341 aagttaggta aacctaaaaa ggagtgtaag atttggaacg tacggccatt gtaattcaag
    11401 acctttcagc cgcttatcaa gggaaaactg ttttgaaaac tatcaacttg acgataaatc
    11461 cacaaaaaat taccggtatt atcggaccaa acggtgcagg aaaatcaaca tttatgaaat
    11521 ctttgctaga gttgatacca gctactactg gtaaagtcac cttttctgga cagccggtaa
    11581 actcagtccg taaaaaaata gcctacgtgg aacagcgaag tgaattggat ctttcctttc
    11641 caattgatgt attaggcgtt gtacttttag gaacatatcc atctttacga attggacaaa
    11701 gacctgggaa aaaagaaaaa gaacgtgcaa gacaagcttt gaaaaaagta gggatggaag
    11761 aatatgccaa aagacagatc agcgaactat cgggtggaca gcttcagaga gtttttattg
    11821 caagagctct agcccaagga gcagaatgga tctttttaga tgaaccattc gtagggattg
    11881 atgcgttaag tgaacgaaag atctttgaca tcttgcagga attgaagaat tcaggaaaaa
    11941 cgattttgat cgtccatcat gatcttcata aagtagaaga atatttcgat gaggttattc
    12001 ttttaaataa acagctgatc gcttccggtc cagtacaaga agtctttaca tcgaagaacc
    12061 ttcaattggc ctatggtgag atcatcagac atttagtaaa aggaggagag aaaaaatgat
    12121 ccaatccttt attgatggat taatgaatta tcaattcctg caatacgctt tggtcacttc
    12181 catgcttgta ggacttgctt ctggagtcat cggttctttt attattttac gagggatgtc
    12241 tttgatggga gacgctatct ctcacgcagt tcttccaggt gtagccattt cttatatgtt
    12301 tggttttagt tacatctttg gagccactgc ttttgggatg ctaacagcag cagtgattgg
    12361 tttcgtgact cagcggagcc gattgaaaaa tgatacagcg attggaattg tctttagctc
    12421 cttttttgca ttagggatta tcttgatttc atatgcccag agtgcgacag atttgtatca
    12481 tattttattt gggaatgtct tagctgttag ggaaagcgat ttgttgctga cagcactcgt
    12541 tagtggaatc gtcttgatat ttgtcttttt cttttataaa gaattgaaga tcacatcatt
    12601 cgatccgaca atggcaaaag cttatgggct gaacacatcg ctgatccatt atcttttgat
    12661 gttctttttg acattagtgg ctgtagtcag tttacagaca gtaggaacaa tcttggtgat
    12721 tgccatgttg atcacaccag ccgccacggc ttacttgcta acgaaccatt tactgaaaat
    12781 gatcattaca gctgcaggaa tcggtatgct aagtgcagtt gtcggtgtgt ttttcagtta
    12841 tagttacaat tggccatcag gagctacgat cgtgttagca tgtaccgcat tttttatcct
    12901 tgctttttta ttttctccaa caaaaggaat tttatttcag aaaggaagca gatagatgaa
    12961 aacaaaaaaa tcactctttt taatcttggc agttagtttc ttggtattag ccggttgcgg
    13021 aaagcaggct tctgaccaag cggatgaagg aagtaaagaa aagttgtcag tcgtggctac
    13081 caattcgatc ttggcggaca tggcaaaaga ggtcggaaca gatcaaatag atatccacag
    13141 tatcgtacca gtcggaacag atccgcatga atatgaagta ctaccagaag acatcaaaaa
    13201 ggcaagcgat gctgatgtta ttttatacaa cggtttgaat cttgaaacag gtaacagctg
    13261 gttcgataac ttgatggaaa cggctaaaaa agaagaagga aaagattatt ttgcagttag
    13321 caaaaatgta gaacctcttt atttaactag cggtgaagaa catacaaaag cagatcccca
    13381 tgcttggcta gacctatcta acggaataaa atatgtggag gaaatcgcac gtatattctc
    13441 tgaaaaagat gcagaaaatg cgacactcta taaaaaaaat gcagaagcat atgtggaaaa
    13501 actaaaagaa ttagatacac aagcgaagga aagttttgct tctatcgaag agaacaaaaa
    13561 attattagta acaagtgaag gggcattcaa gtatttttca cgagcatatg atttgccagc
    13621 agcttatata tgggagatca atacagaaag tcaaggtacg cctgatcaaa tgaaagcgat
    13681 cattgatcag ataagagcaa aagaagtacc ggttttattc gtggaaacca gtgtagactc
    13741 aagaagcatg gaacgggtag caaaagaaac gggtttgaaa atctatgata aactgttcac
    13801 tgattccata gcaaaagaag gagaacaagg agattcttac tatcagatga tgaaatggaa
    13861 tattgaaacg atccatgaag gtttgtcaca aacaaaagaa agctgaaaag tgcaaggtct
    13921 agcttgagga gcagaccttg cattttttat aagagatatg aaaaaaaatt atgctgtttt
    13981 tcgtcgtaca gatacctttt ttgaagaaat tccgttatag ttagagtaag gaaggaaggt
    14041 gtggctatga attttacacg taaagataaa tatacgatta aagaagaagt ctttcgattg
    14101 atcagccagc aggaaaatac cgacaaggat caagaccttc aatttcttga agcagaatta
    14161 gctaaattat tcatagcaaa tcaaaatgag acaacagaac cagatgaaga gctgtacata
    14221 ggcaaatggt tgtttgatga atttcagcct ttagatgaaa ataccggtat cggttatttt
    14281 gtgttccttt ctccagtcgg cttcacacct ggcgtattag ttaaacaaaa cgacgaaata
    14341 accgtcaaag catggcctgc attattttca gtcatcaaag cagaaggagt aatcaaaaag
    14401 atccagtcgg cctattataa aagtcaattt attgccaaca gcaaattaat gaatatgttt
    14461 tataatcgtc tagtagaaat tgctaggcct gggaaaatcc cgcaaacatt cacgtacaca
    14521 cagcaaaaaa atctctatga agaagtattg tattcccgcg atctgtctga gttttcgcca
    14581 tgggaagagg taaggctcca tgaactgtta agtacaaaac cagtttcatt gaattttttt
    14641 aatgcattag ataacaaaag aaaattaatt tcaacaaatt attgggaagt atttgctgca
    14701 agaaaaaaat ggatggaaga aaagaagatt gccgatcagc agatccagtt tgtccagctg
    14761 aaaaaagaaa aactatatta tgggttatac agccgttaac agcaagcgag gaagaccatg
    14821 acattaaaag aagaaatcat acaagaaagc aaacgattag gaattgacaa aatcgggttc
    14881 accacggcgg aaccttttga ttcattaaaa gaatcgttgg aagaacaaaa agcagctggc
    14941 catacttctg gctttgaaca tccaaatatc gatgagcgtc tttatccaga aatgacattt
    15001 gatcagccga aatcgatcat ttccattgca cttgcgtatc ctactaggat ccatgaagaa
    15061 gtgcctaggg atgaaaaacg cgggcagttt gctcgtgctt cttgggggat cgattaccat
    15121 gatatactca gagaccgttt gaaccgattg atcgaattca tccaaacaag agcagaaaaa
    15181 tggcaaaaag aagaggaatg gcgtctagct ccgcaagtag atactggaga actgatcgat
    15241 gtcgctgtag cacagcgagc tggtttagga tttattggac gaaacggatt gttgatcact
    15301 gaagagttcg gttcatttgt ctatcttggt gagatcgtta ctaatattgt atttgagcct
    15361 gataaaccag gagaatttgg ttgcggtgac tgtatgcgct gcgtgactgc ttgtccgaca
    15421 aaagcattgc ttggtgacgg aagaatgaat gcccagcgat gtttgtctta tcaaactcag
    15481 acaaaaggga tgatgccgga agaatatcgt aaaaaaatgc gaaatgtcat ttatggatgt
    15541 gatatctgcc agttagtctg cccttacaat caaggaaaag attttcattt tcatgaagag
    15601 atggaaccaa aagtagacga agtatatcca aaattaaagc caatgctttc gatgtctaat
    15661 aaagacttca aacagcaatt tgggcattta gctggttcat ggcgtgggaa gaaacctttg
    15721 cagagaaacg cattgattgc tttagctaat ctaggtgatc gaacggcatt gcctgagatt
    15781 tcagaatgtt taacagatgt ccgccctgtc atcagaggaa cagcagcttg ggctattgga
    15841 cgtctaggaa caaaagaacc ggaaaaatgg cttgatgtat tagatgaaat attagctaaa
    15901 gaaacagaag aagtcgttat aaacgaattg gaacatgccc agaaattatt gcggagaaag
    15961 ttaaaataaa aaaatagtta acattattca aagtttttgt ccagtaattg ttgtaacaat
    16021 tactggtttt tttgtatttt ttacattttt ttaagagaat ttgataaaaa tcaaaaattt
    16081 ttttgctttt ttttatggat tattgcagtg aatgttacag aatctgcgtt tttcattcaa
    16141 aaataaaaaa acatagaaaa acg
//
LOCUS       DACGDM010000052        16119 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.053, whole genome shotgun sequence.
ACCESSION   DACGDM010000052 DACGDM010000000
VERSION     DACGDM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.053"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            762..1148
                     /locus_tag="IXR05_001809"
     CDS             762..1148
                     /locus_tag="IXR05_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4260304.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1242..1433
                     /locus_tag="IXR05_001810"
     CDS             1242..1433
                     /locus_tag="IXR05_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4260305.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            1947..2279
                     /locus_tag="IXR05_001811"
     CDS             1947..2279
                     /locus_tag="IXR05_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4260306.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2575..2730
                     /locus_tag="IXR05_001812"
     CDS             2575..2730
                     /locus_tag="IXR05_001812"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAQ4260307.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            3006..4346
                     /locus_tag="IXR05_001813"
                     /pseudo
     CDS             3006..4346
                     /locus_tag="IXR05_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4587..6203)
                     /locus_tag="IXR05_001814"
     CDS             complement(4587..6203)
                     /locus_tag="IXR05_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4260308.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            6321..6539
                     /locus_tag="IXR05_001815"
     CDS             6321..6539
                     /locus_tag="IXR05_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4260309.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            6734..7195
                     /locus_tag="IXR05_001816"
     CDS             6734..7195
                     /locus_tag="IXR05_001816"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4260310.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(7388..7627)
                     /locus_tag="IXR05_001817"
     CDS             complement(7388..7627)
                     /locus_tag="IXR05_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260311.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(7651..9174)
                     /locus_tag="IXR05_001818"
     CDS             complement(7651..9174)
                     /locus_tag="IXR05_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAQ4260312.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(9192..9314)
                     /locus_tag="IXR05_001819"
     CDS             complement(9192..9314)
                     /locus_tag="IXR05_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAQ4260313.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(9344..10327)
                     /locus_tag="IXR05_001820"
     CDS             complement(9344..10327)
                     /locus_tag="IXR05_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4260314.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(10351..10500)
                     /gene="rpmG"
                     /locus_tag="IXR05_001821"
     CDS             complement(10351..10500)
                     /gene="rpmG"
                     /locus_tag="IXR05_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4260315.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(10521..10898)
                     /locus_tag="IXR05_001822"
     CDS             complement(10521..10898)
                     /locus_tag="IXR05_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260316.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(10930..11109)
                     /gene="rpmF"
                     /locus_tag="IXR05_001823"
     CDS             complement(10930..11109)
                     /gene="rpmF"
                     /locus_tag="IXR05_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAQ4260317.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(11124..11393)
                     /gene="rpsN"
                     /locus_tag="IXR05_001824"
     CDS             complement(11124..11393)
                     /gene="rpsN"
                     /locus_tag="IXR05_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAQ4260318.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(11916..13688)
                     /locus_tag="IXR05_001825"
     CDS             complement(11916..13688)
                     /locus_tag="IXR05_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260319.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(13642..15396)
                     /locus_tag="IXR05_001826"
     CDS             complement(13642..15396)
                     /locus_tag="IXR05_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260320.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(15506..16075)
                     /locus_tag="IXR05_001827"
     CDS             complement(15506..16075)
                     /locus_tag="IXR05_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAQ4260321.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
BASE COUNT         5230 a         3072 c         2434 g         5383 t
ORIGIN      
        1 aaaaccacga taggtaactt taaacaaaca tgaagagact ttaataagac ttctttatct
       61 gaaaacactt ttgtttctct ctttcctttc tacatcatta aatagtattt tatacgttat
      121 ctaaaatact attcctctgt caaaataagc taacttactt cattataaaa tatccactta
      181 tcgctttcat gtatattcca ccgtaaaaag tacattttat caccgagaac tcatcatttt
      241 tcatcatgat gaatactatt tacatatatc tagttcaaag acaataatta ttatgatccg
      301 ttattatcta agcactatac agataatagg aatttttcgt ttctaaatat tccaatttgg
      361 gaatccaata aaaattttcg ttcaaatacg tgtctattcg aactcttttc tagttgttaa
      421 ttatgaaggg ggaagaaata aaaaatacaa tctatacacg aataagaata ttatccaaaa
      481 ggaggtttta gaaaagattt attatacgta aaaagctcaa gacattttct tagccataag
      541 gacatgtttg atatttaaga agatatatga attttctttt ctaagtataa agataactat
      601 ccattatcaa ctaaaaaaac atttttgaaa ataaacatca gcagtcctat caatgcatgt
      661 gagcttatag aagttattcg cagcgcagca taattgcatt agcttctttt cgtgtttttt
      721 gcctcttttc cctttaaatc ttaatggagg aggtgtgcaa tatgtcagat aacgacgaac
      781 gcgtaaatgc ccagttgatt cgattctttg aaaaggtcat tttgaacacc gctaatactt
      841 attataaaaa acaagaagaa attcaaaaac atgaacaact tgatcaactc ccaccatatt
      901 tgtttactaa agatactata aaatttaaac aaccgattaa tgttttaaat gtgactctcc
      961 ttgttgaaga tataaaatta gcaaaaatcc ttcctttgtt gaaagaacct gaacaaattt
     1021 ttcttatcga aaaatttatc tttgataaaa ctgataaaga aattggaaag gttctgggga
     1081 ttacaagaca gggtgcgaca aatttaaaac atcgacttta caaaaaaatt caaaaaatgc
     1141 tggtttaata tctgcataat aactaatttt gtatgcttct ttgctcgttc tcctccttcc
     1201 caaagaaata gattataagt ccatgggaag aaggtagatt tatgaattct ttaaaagaag
     1261 atttcatttt agcaaaggct ggaaatgaag aagctgttga ggcaattctc aaaagattta
     1321 gctctttgat tcataagcaa tcctggagaa ctggaaaata tgatcaagat tgttatcaag
     1381 aatgtatgct tgcaatatat ctagctatct cgaaattcga aattaaagaa taactcaact
     1441 aagggagtct gtgacataag taaaaagata gtttcaaatt tcgaacaata aatttgaaac
     1501 tatcttcttt ataattataa agtatcgatt ttacagcgtt ctataatgat tcatagaatc
     1561 taaaacgaat gattttaatt atcaacgttt tttaattcgt ttttagctta aaaataactt
     1621 ttgtcacagt ctcactccta aaattacttt atttacgtat gaagtgggca ggaggtcgaa
     1681 tccagaactg ggctatggta cttcaacgag gacttctcct ctagaattga aaagcatgcg
     1741 atttaccttc cgtaacgacg gtagatttat tcaactatgt gtccaatcaa aatttgtctg
     1801 atttcaaaaa tagtcaagag aattttggtt gttaaaaact cttatctatc aacttccaca
     1861 gtttagttga caaaccctga tactaagttg ggctatgata cacttttctt gactatcagt
     1921 tacgttaccg gaaggaatga actctattga gaaaaacata tgatcgtaaa tttaaactaa
     1981 agatttcaca ggatatcctt gagaaaaaag taactaccaa gaaaattgct gaagaataca
     2041 atatctctcg tccaacaatt tcccgatggg tttcagaata tcgtcgatac gggaaaaatg
     2101 cttttgctgg acaaggaaaa agattacctg ataaagcaga tttctacatt cttgaacagg
     2161 aaaataaacg actaaaagag gaagacgagt gttctacgaa cacaaagatc gatacggatc
     2221 tccagggatc actcaaaaac tttacgatga aggaatcgaa atcaataaac gtgttgtagc
     2281 tgttcttatg cgtgaaatga atttatgcac aagaggattt catcgacgca aatcttctca
     2341 tggtagagaa aaaacaatca aagaaatggt aaaaaaatgt tgaatcgata atttgaacag
     2401 aaccaaattg atgctgtttg ggtgatggat attacttaca ttccatgtaa tgacggtcgc
     2461 ctctatttgt ccacctatat tgacttagca actcgtattc tacgttacta tatggtagat
     2521 tcacacatga aaaaagagat tgtcgtccgt ccattacaaa tttattaagg agaattgcct
     2581 acggtaattc attccgatag aggtagccag catcggtctt ttatttatca agagctgttg
     2641 aacgaccacc acatcacaca ttcagtgagc caaactggga ctcctgttga caatgcagta
     2701 attgaagcgt ttcatcgatc aatcaaatga gaattaatcg actccaacaa atataaaagt
     2761 aaaatagaga tgaaggtgtt aatccaagat tatttagaag actactaccc aaacaaaaga
     2821 atccatacaa aatttatgat gactccttga caatttgaag cgaagaaaat aagggatcta
     2881 taatatctag tgttggtgac gccttctgtt gccaatactt tttctttttt ctaataaacg
     2941 caaacagaca ccttaaaatc ctttagaata aagtcgacga aaaccattca aaggagtgtt
     3001 tcaagatgtc ctattcagag tttaccaaag agttactaga tattctagac ctaaatctta
     3061 tctttcatga agatgccttt cgcaaagagc gaatcaatga cgaaacatgt tttgtttttg
     3121 atggcacatt gacctatcaa ccggaggaat gctttcatcg ccactatcaa aatgaacaaa
     3181 cgatcattaa atagggctgg aaaaaagtat ccatcttatt gaatgatgtc agtaactaca
     3241 agaccattct gcggattaac aaacagcgct tcaaatgtaa acactgtgga aagacttttt
     3301 tagcagaaga ttcagttagt gatcgtcgct gctccattgc tcgcagagtc aaacaagcca
     3361 ttcttgagct attaagcgaa cctctttcta tgtctttgat cgcacgtatg aagcacattt
     3421 ctccgaccac tgtcattcga atacttcgca gccttcggcc taaaaccatt tctttgagcc
     3481 agctgttacc agaagtggtg tgtttcgatg aattcaaatc agtgaaaaat gtctcgggag
     3541 ccatgagctt tgtcatgatg gacggcaaga cccatcaact gattgatatt gtggaaaatc
     3601 ggcaactcaa tcctttacgc gactatttct tgcgctaccc tataaaagtc cgtgaacaag
     3661 tgcgtctagt ggtttcagat ttctatacac cctatcgcac attggtgaaa gagtgttttc
     3721 cgaatgcccg aatcgtcgcc gatcgctttc atattagcca acacattggt cgggctttta
     3781 ccaaccaccg aattcaagta atgaagacct ttaaaaaagg ggatcgtcgg tcgaagcact
     3841 taaagaaata ctggaaacta cttcaaaaga atgcgtggga attgaaaggt cagcatcgct
     3901 actggcgtcc gtcatttcga gatcatctga cagaagcaga gatagtcgat cggctattat
     3961 cttatgatga ttccttaaag cgaggctacg aagtctacca ggattttctt tccgttatca
     4021 gaagacaaga tgttcctgaa ttcgtcgcgc tcctaaaaga agactacaag gagttgccag
     4081 agcactacca accagtgttc acgaccttca agaaatacca aacagaaatc aaacgagcgt
     4141 tgcgcgttcc ctattccaac ggccctatag aatgtttgaa taaccatatc aaagtactaa
     4201 aacgaattgc ctatggctat agaaactttc aaaactaccg agaacgaatc tttttatatc
     4261 gaggaaaata ttttaagaaa actaagaata ctacccaact gactaaagcc agaacaacaa
     4321 cacggctaga caagatagct gtctagccgt gtgagtatct cgattattct attgaatttc
     4381 ttcaccaaca ctcattgacg aagagccaaa ataagtaatc taaccgactg ttaactaaac
     4441 cattgcaggt cccgttaaag atacttgtgc ctgttgtcac cgcttctttt tcttgtccac
     4501 aagcgcttaa cacacttaat aaagcccctg ctattattaa taataatatc tttttcttat
     4561 taaaaacctc ctcatctatt tccagattag taaatgtagt aatctgtgct ttcttttttc
     4621 tcaatactaa taactaactt atggggtaaa caaatactcg tttgaccggg ttttgagatc
     4681 catccagttc taaccgcgat ttgatcagga ctattatctt ctttaactcg aattcttcca
     4741 tctttaatct caacaatatt atattgtccc ttcgcaggat gataattcac gagtttatga
     4801 ttgatcttat ccaaatcgaa gcgatccatt tccttgccat caattcgaac gatggcatat
     4861 ttgatagcat cttcagttgt ttcattctcc ttttctatag agaatacaaa taagggaata
     4921 aaagaggtaa taatcaaaat gccaataatt atgacatcgc ctatcttgac accagctttt
     4981 cttaaaaatt tcattaacga tatctggcta aacatattag actttttcca tggaaatggt
     5041 gaaatttttc ggaaattatc tgcattaaga gaatcagtta aacaaccctc aagttgttcc
     5101 ttaatacatt gttgatccat cttcatacca ataaaaacta gtttattaat gcgttcacca
     5161 aacaacggat gccaggcttc cttcaattcg ggattttttt gtataatcat ttgacactca
     5221 attttaggta aactagctac ccaataattt aatgattcaa tacttttata gctacccgat
     5281 gtttcaaaga tcgtcgaaaa atcactatgt tgggcaaacc aaagaaaccc ttttgctctt
     5341 gtaatattgc caggaaaatt tttatccgta agatgggcaa atttttgtgc gtcaaggagt
     5401 aaccgatttc gatagataaa acttgagata ccatattctt ctgtttcagg aatatgattt
     5461 tgatagccaa gctctaactc tttgaaccag cccactgaat aggaagtctc atctatatta
     5521 aaaagatttg tatttagaat tttcgataag tctacttcac ctttaattgt cctaattatt
     5581 ttggcattgg actgtaactt agcaattaga ccgttaattt tgtaaatcgt cttggttgac
     5641 actaagtcac tattatttaa aagtaatatg ttacaacact cgaattgatc aattaacaag
     5701 ccacgaatat cctgttcttc ttcaactaca ttaccttcag cttttctttc ctgaatcttt
     5761 tcacccgttt cgaaattatc ccaaaaacgt tttacatcca ctactataat aatggcacca
     5821 atctctaatc gttgggtcaa atcaatgtct aaagggtttt tagctaatat aattgcttga
     5881 ataattggaa ttggtttgct gattcctgaa gcttcaataa caatttgatt caagtcagaa
     5941 aattgcacta attgatctag ttcaacaatc aaatcttcgc gtaatgtaca acaaatgcat
     6001 ccattcggca tcgaaacaag tttttctcca gttcttttaa aacctttctt gtcgactaat
     6061 accccatcaa catttacttc ccctatgtca tttacaatga cagcaatttc ctttccgtga
     6121 tcaccgtaca gaatatgatt tagaagtatc gtttttcctg aaccaagata gccagttaag
     6181 attgtaatag gtattttttt catagggaac ctctttctat accttgaatt tacactttaa
     6241 gtgcaacaca taaaaatgag tcataatcga tatccaacta gtataagttt gtcgagaaca
     6301 ctcctagaag gaaaataatt atgagccagt atcgtcatct tactatactc gaacgagaaa
     6361 gaatctttct gcttcacgaa gaaggatttt ctattagtat aattggcaac gacattcagc
     6421 atagcccgtt tactatttta catgaactga gaagaaacaa gaaaaaaact attcaccttc
     6481 caaagcggaa aaaaattatg cttatcgaag aaaaaaatgc ggacgttatc acattctaaa
     6541 tgatccgtga gtttggtcaa ttgttcgtca tttatttgtc gattttcagt ggtcgccaga
     6601 ggaaatctcg aatcgtttga agcatgaaca tatggacttt tcaattagtt ttatcacgat
     6661 ctaacgtgca atttgcaatg atcttttcga tacagaaccc ctctcacacg gcaataaagg
     6721 cctgatccgt tcattgcacc atcgaggaaa aacaagacat acaaaaaatc atgtcgagtc
     6781 tcgtggaaag atttgcctta ctcattcgat ccatggccgt ccaaaatccg cagatgatag
     6841 aagtgatttt ggtcattgga aagccgatat tgtagctggc aaaactggtg gtacttgttt
     6901 agtgactttg acagacagaa aatcatgctt ccttttagca ggaaagaagg tccccagaaa
     6961 gaaagccgct tatgtgagcg agaaaatgat tgaactttta agcagtattc caaatgaggc
     7021 ggtcaaaacg atcactccag atagaggaaa agaattctcc aatcatttcg cagttacaga
     7081 agcattgaat aatatgccct tttattttcc agatcctcat gcccttggca acaatgaaca
     7141 aattaaaata cgaatagact cattcgagaa tacttgccaa aatcgaaaga gatagctacg
     7201 gtagataact caacgataaa tcagatgatt gaaaaactga ataacagacc tagaaagtgt
     7261 ttagattgga gaacacctta tgaagtcttc tttgataaag tgttgcgctt gatttgacaa
     7321 ttcaagacat aataaaaagc agatcaaatc caaataaggg aaaaatgatc tactctggta
     7381 ttatcaatta attggccaag ctattatgcc gttttgctaa acgtctactt cttccagtat
     7441 tgaccttgat aaaacaacaa tcaggatccc gttttaatac tctatgaact gtgtcaatac
     7501 taacatgtaa agttgcagca atatcagcta atgtactccc atttaatctc atttgctttg
     7561 caaatcgata acgccgataa gcatcaatat tcttggaatc catagacaat aatacttttc
     7621 ttaccatgta tttcctccaa aaattgaatt ttaatgagcc atcatttctt gagcaatttc
     7681 atgtttagac aatgaagctg gatagaaagt aggccaatta tgcaattcat tatagagttt
     7741 ttcttgactt tctccaccaa agaaaatatg gaaatgctct gccttacttg gtgcaattcc
     7801 atgatcacta aattgaatat atttaaaacg accagcacct gcatcatcag tttcaaaatt
     7861 aaaacgaaca ccacggtttc ctttttcata attcaaaatt ttgtatccaa catatttgta
     7921 tgtgtattga tgatgttcac cgttgactac aaaatcaatg gtgttgtctt taatgttgat
     7981 agtatcaata tctgtcttat agccagtagt ataataatct ttgtactcgg cagctgtcat
     8041 gtctttattg atttttgctt tgtaatcgaa aacttcatcc aaaattccat cttttaacaa
     8101 cggataaaca gattgccatt cgcctgtata atcactcaat tcgcgatcct tcacatcggc
     8161 atctttaaag tacccattag caactgtctt ttcatccttc gcttcttttt ctggaactac
     8221 ctcttcacca gcaaccatag ttgttttttc taacgctttt agattgtctt ccattactga
     8281 aacataatct tcaccattat ccatttgttc ttttgtaaga ctttcaagag gattcagtac
     8341 ttccaatttt atcccagctt cgttggccaa agtttttgca attttatcat tagcattctt
     8401 ttcaaagtaa atataattga tcttattttt tttaacatac tcttttaatt cagctaatcg
     8461 accagaagat ggctcttctt caggacttag tccagcaata ggaacttgtt tcaatccata
     8521 atccaaagct aaatatccaa aggctgcgtg ttgcgtcaca aaactttttt gtttcgcttc
     8581 tttaagacta gtggtatagt cagcatccaa ccgtttcagt ttagtcaaat acttttcagc
     8641 atttgtctca aatacttttg cttttttcgg atacaattta actaactgat ccttgatatt
     8701 tgaaacttcc ttaattgcca ttttgggtga aacccacgta tgaggatcta gttcatgatg
     8761 gtgatcttct tctccgtgat catgatcttc ttcttcacta cctggcaata aaatcatgtc
     8821 ttttgttcct tctactacat taggcccagc tttcttccaa ctttctttag cttttggtac
     8881 ccatgattcc atgttttcgt tatgatatac aaaaacatca gcatcatgag cttttgccat
     8941 atccttagct gagggctcat agtcatgagg ttctgatccc gctggaacca ttaaatccac
     9001 gttcgcttca tcgccgacga tgtttttggt gaaatcatac attggataga atgttgttac
     9061 aatttctaat tttccatctt tatcattcga tacttttgca tcattagtgc tggagcaagc
     9121 tcccaataat cctagagctg ctatcccaat aagtcctaca ctgattttct tcattctttt
     9181 tccttcctta attatgctaa tttcttcatt ttatttcgtt tatgttcttt gataattttt
     9241 aatgcccttt ttctagtttt aatattcggg cttttaagtc gtcgatatgc actagatata
     9301 tccgttttct ccattagaaa ttacccccaa tcactactta tcattatttg ctttccgcca
     9361 gtaatttatc aaaactctgt ttgatccttt cttcatccaa catttttccg attagaataa
     9421 tagtggtttg gtctttttgt cgagtggtgt attgaaaatt aacctgttcg tttacctctt
     9481 gcatggcaac tataaaatcc tgctcttgta aagcaatcaa tcctttaaaa cgatacaggc
     9541 tcccttggtt ggttaaaatc agccagtcaa tccattggag taaaaaatct ttttttatgt
     9601 cttgatctga agttaagaga attgatttaa actcatgtac ttgatggtgt tgatgatagt
     9661 atttgccatt atagtgattt tctgatgaat cactttcaaa aactaaggga tgattaaatt
     9721 ttttcaaatt ataaaaatcc tttttttgaa tcgtttcact atgtgtgaac attcgaatat
     9781 cggataaagg gttaatactt ttgatttctc tctgtaattt ttttagtgca gataaattca
     9841 agttttgttt tctagacaca aaaatgcgat ctgccatgac aagttgctta agggcttgtg
     9901 gttctctttc aataagttca aaactgtcac tatcaataac agtcaataaa ctatcgatat
     9961 atactcttcc tcttagttga ggcgctgtta aaagtgtttg aatgattggt tggggatctg
    10021 ctatacctgt agtttcaatg atgatttgtg aaattggttg ttgatgttct tctattgttt
    10081 ccagtaaaga aatcaatatt gctaataaat cactgcgaag actgcaacac atacatccat
    10141 tatttagttg taacacccgt tcctcgctat gaactaataa tttgtgatca atcccaactt
    10201 caccaaactc attttcaatt ataataattt cttccctggg gtagggtgag acttgcaagg
    10261 cttgattgat tagcgttgtt tttccagccc ctaaaaaccc agaaacgatt gtaactggta
    10321 tgcccatttt gtcacctttt taccacttag ctatttcact tctttaaaaa ttgcccgtct
    10381 gcgcaatttt ggcgaatact tttttaattc taaccgttca gggttattcc gtttattttt
    10441 gctggtgaga tacagacgtt ctccagtttc gacacattcc aaaataatat tttgacgcat
    10501 aaatcttcct ccttcaatac ttatcgatct tcaagatatg cttgaatttg ttgtgcatct
    10561 tcaaaagtta actcgccaga ttccaattgt gaaactaaat tttctttcat atcaacaggt
    10621 atctcccaat aaccatcgat acattgaaat aactcctcgt catactcttc aaaaattgga
    10681 tagattctta aaaaatcatc aaatgataag ccttggtcct catagtaatc tttgactaat
    10741 ccattttcaa ttgcctgttg ggtcggtaaa cccgtttcag taataattcc tctctctacc
    10801 atcgaacgat aaaaagtgca tttatctagc gattgctggg tcgtttcaag ataatacttt
    10861 aatccttctt caactaaagg tgggtaaata atttccattt tgattccctc ctaaaagtta
    10921 tatattaaac tattttgaag ctcctttaat tactttcttt ccattatagt acccttttaa
    10981 agatacatga tggctacgtc tataatcacc attcgcttcg tcaaatgaaa tttctggttt
    11041 tactacagtt tgatgagttc ttcttaaccg tttcttcgcc ttagatgttt ttcttgctgg
    11101 tactgccatg atatttcctc cttttaccaa cttgcttttt ttactccagg aatcaaccct
    11161 tgatgggcaa gttctctaaa cttaatacgg gacataccga actttcgcat ataccctctt
    11221 ggacgaccat ccgtctgatc acgaagcctc agacgattcg gatttgaatc tcttggcaat
    11281 ttagcgagag cggtgcgatc tcctgcggct tttaattcct gacgtttatc tgcatacttt
    11341 tcaatcatcg ccatttgttt ctttgcttta gcaattttcg acttttttgc catatacctt
    11401 tatactcctt ttattttgat ttagacacct caaatcgtaa tcgttacgtt ttgacactga
    11461 tactttacca acaagagttg ctcttgtcaa caataaataa catgaaataa aactcatatg
    11521 aatagataac tatttgaaaa cgaatttatc ggtacataga gataatcaaa tcatttaaaa
    11581 gaatatgcag tttaggctct gaaaaataag aattcacttt tattagtcca atcaaacaca
    11641 aataccgttt taagtagctt ttcctctact taaaacggca atatgaaaga aactataact
    11701 ttttattcaa tcttttatgt ttaactggtt tatcgccaat tttttaaaac tttgattatt
    11761 ccttatatta taagaataga cattaagtga actaattcaa tcatactgat tctttcgtgt
    11821 attcaaaatt agatgctgtt taataaaatt attctttttg aaaaagaatt ataactatat
    11881 cccaaaaatt gtaggttaat ttaaagccta tttcatcatc gtgattgagc ttctttttca
    11941 tagacgaatt tctcagatag tttagttttc tttatgagat ttttgtatat ttctgacctt
    12001 cgatacaact cattatgagt accttgatca actagttttc cttgatccat cactacaatt
    12061 ttatttacct tttcaataga cttcaagcga tgcgatataa ttagtactgt cttatcttgt
    12121 attaaacgat ttaaactttc ctgaatacgt ttttcatttt ccgcatctaa actggcagta
    12181 atttcatcta aaattaaaat tggcgcattt ttcaaaaaag cccgtgctat ggataggcgt
    12241 tgtcgctctc ctccagaaag tgaacttccg ttttctccga ccaatgtatg ataaccgtca
    12301 ggtagttttt caataaagtc ttcgcagtta gctaaacgag ctgctttttt cacttcctca
    12361 tctgacgctt gactatttcc aatacgtata ttttccaaaa tacttgtatt aaacaaagtt
    12421 acctcttgaa aaacaatagc gattttgcta aacaaagaag ctggagatac acgtttaata
    12481 tcatacccat caattaaaat acagccttca tcataatcat acagtctaga cactaatttc
    12541 aagatactag ttttcccgga accactagca cctactaacg cagtcacttc tccttgttta
    12601 gccgtaaaag agatatgatc taaaattggg gtattgttat catatgagaa agagacatct
    12661 cgcaactcaa tgtcaaaaga tttcagagga ctatctgatc cctcttggat actggtttcc
    12721 ttcatagctc taattcgctg tattttagga gctaaataaa atatttcaag cactgcttct
    12781 ttcatagaat cgaaggaatc ctttattttt attgcggcta gtaagtaacc aacgacgtag
    12841 agtatagtca cttcacccgt taacagtaag tgaacaccta ctagaatgac tactgctaaa
    12901 ctaacatatg agaaaataga ggataaggcc atgactgaaa aagtacttaa ttctaccttt
    12961 aaatgaatcc tttcactctc ttccattttt ttgaaaagtc tgtcttgaac ttttttagat
    13021 agattaaagc tattaatctc ttgctgcaat tctatagttt cttgaaattc ttccgagttt
    13081 tctctcaaag tatcgtaata tttagtattg gctttcgttt gggatttctt tgataacaag
    13141 attaagacaa aactaaataa cgttggcaaa ataacagcta atcccatttt gacattacca
    13201 accaaaagca tcactgaaat aaaagggaaa aacagagcca taccgccggc tttaggtatt
    13261 gcatgactca tcgcatgctc aataccttca acgtcagaca tgatagtttg agataaatct
    13321 gataaattat gttttgaaaa ataggataat ggtaaatttg acaaatcgtc tgcaatttgc
    13381 actcttaaat gcgcactttc tttataagta ctattatata agttttcata ctccctatct
    13441 aacaaccaat acatgaaaag caaagtaaca aacgatacgg caaaataaag ccaacggggc
    13501 tttgtatttt ctaaaactaa ttcgtctatc agcatcatta taatgaatgc tggtaccata
    13561 ttaatgcagt atacaaaaaa actagaaata gaagctttag ttaaagcttc tgcgccctga
    13621 tcacttaaag caaatttgtt tttataaaaa cttttcattg tcaagcctcc aatcatttgc
    13681 attctcataa ttagtgacca attgtttata cacttgatgt ttagccatta attcattatg
    13741 atttccacgt tctactattt tcccttctga caagacaaga atttcatcta cagatttaat
    13801 gctggataat cgatgagcta tcataataac tgttttttct ttcatcagat gttgaaaagc
    13861 cttttgtagt tcatactcat tatctggatc aatagatgca ctggcttcat ccataataac
    13921 aatctttgca tcttttaaaa ttgctctggc aatagctata cgttgttttt ctcctcctga
    13981 cagataaact cctttactac caattaaggt atgctctctt tcgggaaatt tttctaaaat
    14041 cgattcgcaa ccggctaatc ttagcgcgtc aaatacttta cttgctggcg cttgaggatt
    14101 tgctatagaa acgttatcgt aaatactctg attgaatagt ttcgtatctt gaaagacaaa
    14161 agcaattgtg ttaataattg tgtcttttga atagtgattt aaaggcttac caccaatttt
    14221 aatctgtccc ttatccacat tgtagaaacc tgaaattagt ttagctatcg tactctttcc
    14281 gcttcctgat tttcctacta atgcataaat tcttttttgt tctaaaacta agttgaaatt
    14341 ttctaaaaca cactcttctt tgtatgaaaa gctgacattt tcaaatgcaa tgtcacaatt
    14401 tttaatctgt gtctcgttcc catattttag ttggtcttgc ttcatttcta aataaaggga
    14461 gtctagtgtt tcgactgcat atcttgcttc aaacaagtgc atacttacat acattattct
    14521 catgaaagaa acaaaaataa ttccacttaa aaaaaacaac atcaacaagt caacagctaa
    14581 tatcttggga gtggtaagag aagttataaa aaaggttata ggaactatca aaatgcaaac
    14641 tatgccaaaa aatagccatt gaaaaagaac aaaaggtgtt ttcccactca aagaatactt
    14701 atatgcaaac ttagcataat cgttaattgc tttattcaag gctttaaatg atgttacttt
    14761 agcaccaaat atctttataa cttgaattcc gcggatatat tctaccgttt cagagcttaa
    14821 cacatctaac gattcttgat atttttgaat aaaatttgta ttctctgtca ttttctttaa
    14881 caagaataca ccaattacta acatggcgat tagaaccaat ccaattttaa agttaatgaa
    14941 aaagcctaag gcaactgata aaacaggtgt tactatggct tgagcactat ctggaatcaa
    15001 gtgagcaatt gccatatgtg ttttagccgc gttgtcatca attgtctttc gaatatatcc
    15061 cgaagaattt aaatcaaaaa aacgaaaact tgcttctgtt aaaccgctaa ttcccttttt
    15121 tctcaaatta gtctctaagc gaaacccaag gatatgagaa aataagccag aaaaaatata
    15181 aaataaagct cctaaagtta accaagcaac agtttgaacc gcataactct tagctaaata
    15241 ttcatctcct acaataatta gagactgaag aaatttgtaa atactgtaat atccatagac
    15301 tgttaatacg acagaaaaat cagaaaataa agtggctaac catccgtagt atttcatttt
    15361 agggacataa ctaaataatt ttttgtatac tttcattttt tcctcccccg cattcaattt
    15421 cttctcttat tcgtttacaa ctgttaatgc tttccgtaat agcgtaaatt agagatgtac
    15481 aaacagataa aaggtaaact acgttctatt ttttgtattt ttttaagact tttcttccaa
    15541 tcaatacacc aatcatagat aaacttgcta caactaacac tgaaatgatt ccccatatac
    15601 ctaccgcata gtggatcatt gcatccattg ttgcagcaga ttgtccttta tctatccaat
    15661 cttgacgaaa acgatctgta aagaaccata taggaatcca ctgtccggca gcactgccta
    15721 attgcattag agcccaagac gcaacttgag gaattgctcg atcatatcca aatacagata
    15781 gaataatatc agctaagatc gccatactaa tcgaactgat aaaccaaggt aagtacgccc
    15841 cgcccattaa cgtaaaaaat aacaataaaa caattgtgta aatagtaaaa attccttttc
    15901 tagggtagtt atagctaata taaacaaata tgattccaga taataatcca aaaatcccgg
    15961 gggatatgct gtgaccaaac gccccaccaa tactactaac cattattgaa aaaaagtaaa
    16021 ttactaggga aataactgta gctaaaccaa taaaaatata atcttttgtt ttcatatata
    16081 ttctcctcaa ttctatttcg ttatgtcatt aaaaatctg
//
LOCUS       DACGDM010000053        15950 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.054, whole genome shotgun sequence.
ACCESSION   DACGDM010000053 DACGDM010000000
VERSION     DACGDM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.054"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(387..809)
                     /locus_tag="IXR05_001828"
     CDS             complement(387..809)
                     /locus_tag="IXR05_001828"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAQ4260322.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            complement(823..2229)
                     /gene="atpD"
                     /locus_tag="IXR05_001829"
     CDS             complement(823..2229)
                     /gene="atpD"
                     /locus_tag="IXR05_001829"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAQ4260323.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            complement(2252..3154)
                     /locus_tag="IXR05_001830"
     CDS             complement(2252..3154)
                     /locus_tag="IXR05_001830"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAQ4260324.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            complement(3168..4724)
                     /locus_tag="IXR05_001831"
     CDS             complement(3168..4724)
                     /locus_tag="IXR05_001831"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAQ4260325.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            complement(4747..5289)
                     /locus_tag="IXR05_001832"
     CDS             complement(4747..5289)
                     /locus_tag="IXR05_001832"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAQ4260326.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            complement(5276..5800)
                     /gene="atpF"
                     /locus_tag="IXR05_001833"
     CDS             complement(5276..5800)
                     /gene="atpF"
                     /locus_tag="IXR05_001833"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAQ4260327.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            complement(5891..6106)
                     /gene="atpE"
                     /locus_tag="IXR05_001834"
     CDS             complement(5891..6106)
                     /gene="atpE"
                     /locus_tag="IXR05_001834"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAQ4260328.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            complement(6159..6878)
                     /gene="atpB"
                     /locus_tag="IXR05_001835"
     CDS             complement(6159..6878)
                     /gene="atpB"
                     /locus_tag="IXR05_001835"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAQ4260329.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            complement(7180..10023)
                     /gene="rnr"
                     /locus_tag="IXR05_001836"
                     /pseudo
     CDS             complement(7180..10023)
                     /gene="rnr"
                     /locus_tag="IXR05_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418328.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
     gene            complement(10026..10772)
                     /locus_tag="IXR05_001837"
     CDS             complement(10026..10772)
                     /locus_tag="IXR05_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4260330.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLRWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            complement(10884..11120)
                     /gene="secG"
                     /locus_tag="IXR05_001838"
     CDS             complement(10884..11120)
                     /gene="secG"
                     /locus_tag="IXR05_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAQ4260331.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            complement(11238..11516)
                     /locus_tag="IXR05_001839"
     CDS             complement(11238..11516)
                     /locus_tag="IXR05_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4260332.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            complement(11629..12597)
                     /locus_tag="IXR05_001840"
     CDS             complement(11629..12597)
                     /locus_tag="IXR05_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4260333.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     regulatory      12812..12856
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            12880..13854
                     /locus_tag="IXR05_001841"
     CDS             12880..13854
                     /locus_tag="IXR05_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAQ4260334.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     gene            13859..14434
                     /locus_tag="IXR05_001842"
     CDS             13859..14434
                     /locus_tag="IXR05_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4260335.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(14501..15640)
                     /locus_tag="IXR05_001843"
     CDS             complement(14501..15640)
                     /locus_tag="IXR05_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAQ4260336.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT         4357 a         3443 c         2856 g         5294 t
ORIGIN      
        1 ctgagccaga atgtggttca ttctgactca gatttgattt tgcacaactc atcagtcctt
       61 attgacaaag agcccaaaag tcttgtcgca gtcccttatt ccaaataaac ggtgttcaat
      121 catctgaccc tcggtattag ctcaaaaaac ggcaaaatat gaggaactat tttccatttg
      181 tttctctaat actcaggaca aaacgctgat ttcacaacct ccgatatacg gtgttccaga
      241 agtagcttct tcgaaaaata agctgagatt tcacaaaaat ttgagaagca attttcgtaa
      301 attccttctt atgtcttgaa gctgaccact tctgtcataa cctcttttta ctgttcttaa
      361 acacggataa acatccgcat ctcattttat gagtgcttag atactttgat acgattgatt
      421 gctcggtgca acgcaacagt tgcccgtttc aattcgttcg tatcttgttt tgcttttgct
      481 tcttcgattt ggcgttctgc gcgttgtttt gcacgttccg cacgagatac atcgatatca
      541 cgttcacgtt ccgcactatc agcaacgatt gaaacaacat tatcacgaac ttccatgatt
      601 ccgccattaa cagcgatcca atcgacgtgg gtatctgaat ctgttcgttt tacacgaact
      661 tcatcaatcg tcaatggaac gatgattggt gcatgtttag gcaaaatccc aagctcacca
      721 gctgtcgtac gtgcaacgac gatagctgca tggtgatcat agaccaaacc ggcaggagtt
      781 accacattta ctgttaaata ttgatccatg gggcacccct ttctagtagc ctagtgtttt
      841 cgctttttct acgacgtctt cgattcggcc aacacttcgg aaagcttctt caggaagatc
      901 atcgtatttg ccttccaaga tttcgcggaa tcctttcact gtttcttcta cagggacata
      961 tgaacctgga agaccagtaa attgttcagc cacgttaaag ttttgtgaca agaagaattg
     1021 gactctgcgg gcacgagaaa ctaacacttt ttcttgatcg gataattcat ccatacctaa
     1081 gatagcaatg atatcttgta attcacgata tcgttgcaat acgtgttgga cttctgttgc
     1141 tactttataa tgttcttctc ccacgatttc aggtgctaaa gcacttgaag aagaagccaa
     1201 tggatctacc gctggataaa tcccttgttc tgttaattta cgttccaagt tggttgtcgc
     1261 atccaaatgg gcgaatgctg ttgccggcgc cgggtcagtg tagtcatcgg ctggcacata
     1321 gattgcttgg atcgatgtga tcgaaccttt tttcgtagat gtgatacgtt cttgcaattg
     1381 acccatttct gttgccaatg ttggttgata accaaccgca gaaggcatcc gtcctaacaa
     1441 ggctgatact tcagatccag cttgagtgaa acggaaaatg ttgtcgataa acaacagtac
     1501 atcttgacct tctacatcac ggaaatattc cgcaatcgtc aaaccagtca aagcaacacg
     1561 catacgtgca cctggtggtt cgttcatttg tccgaacacc atggctgttt tttcgataac
     1621 tcctgaatct ttcatttcat aatacaagtc attaccttca cgagtacgtt cacctacacc
     1681 ggtaaataca gaaataccac catgttcttg ggcgatatta tggatcagtt cttggatcag
     1741 tacggtttta ccaacaccgg caccaccgaa tagtccgact ttcccacctt ttaaatatgg
     1801 ggcaagcaaa tcgataactt tgatccctgt ttccaaaatt tctgtacttg tacttaattc
     1861 gtcaaaggct ggtgcttttt tatgaatttc gcttctttcc gcatcttctg ggaaaggtgt
     1921 ttctaaatcg atcgtatctc ctagtacgtt gaatacgcga cctaatgttt ctttacctac
     1981 aggaacagag attgctttgc ctgtatcaat gacttccatt cctctttgta aaccatctgt
     2041 tgattccatc gcaatggtcc ggatcactcc gtcccctaat tctaacgctg cttcaagaac
     2101 aacttttgat ttattttcgt catttttata aacaactaat gcgttgttga tatctggtaa
     2161 ggattggtct aaagaaaatt ccacgtcgac aacgggaccg attacttgaa caatcttgcc
     2221 tgaactcatc ttttttcctc caatctcaat actattctag tgccgaagct ccggcaacaa
     2281 tttcggtaat ttcttgggta atagcccctt gtcttgcacg gttgtaagaa accgtcagct
     2341 catcaatgat attagcagca ttatcagttg ctgttttcat tgctgtcata ccagcagcat
     2401 gttctgctgt tttggcgtca acgatcgcac cgtagatcaa actttcagca tactgaggca
     2461 ataactgaga caagatttct tcttttgaag gttcaaaaat atattcttgt tcgaaagtag
     2521 ttgcttcttc tggatctaag tctgagattg gcagcatttt ttctacacga aactgactag
     2581 ttagcgaatt gatatgatgg ttataacata cgtataattc atcgaatact tcgttttggt
     2641 acatagttgt tgccatattt acgattttgc ggacttcatc aaagcttggc tgatcagata
     2701 gattgcgcag ctcatatgct agattgatac cgcgtgcttt aaagaagtct gcaccagttc
     2761 cgccaattgc gatcatcacg taatcatcgg gtgattggtg gtcttcttct aaaatagaca
     2821 tcgtttgttt caatatcgag ctgttatatc caccgactaa accgccatct gcagtgatga
     2881 cgatataacc cgttttctta acaggacggc tgagcaacat gctgttgtaa ttgatatccc
     2941 ctctaggatt ttctgaggca atatcattta actgagtagc agtcaaatgc gtaacgattt
     3001 ctcttacttt tgttgcataa acctgaaact tctgtgaaga agcttcagat tttgtcaact
     3061 tagaagcaga caccatctgc attgcccgcg tgatttggct cgtttttttc gttgaagcga
     3121 tacgtgtctt gatttcattt aatgaagcac ccattcatct cacctcacta tgcattttga
     3181 atggatttca atttatcttc tgtagaggaa ttatttcctt ttgtagctaa gaacatgtct
     3241 ttatattcct gaatcgcact gttcaacgct tcttcttctg gaagatcttt tgttgtacgg
     3301 attgtttcaa agatatctga atgattggta tccagatatt cgaataattc atgttcgaag
     3361 tctaaaatac tgtctacagg gatactatct aagaatccat gtgtcaaagc atacaaaatc
     3421 actacttgtt tttcaacagc tagcggtgca tgcaattttt gtttcaagat ttctactgta
     3481 cggcgtccac gatttagttt tgcttgtgtt gctgcatcca agtcagaacc gaattgtgta
     3541 aatgcttcta attcacggta acttgctaag tctagacgta aagtcccagc aacttttttc
     3601 attgctttga tttgcgcaga accccctaca cgagatacag atagtccggc atcaaccgct
     3661 ggacgagtac ctgcgtagaa caagtcgctt tctaagaaga tttgtccatc agtgatcgaa
     3721 ataacgtttg ttgggatata agcagagata tctccagctt gtgtttcaac aaatggtaag
     3781 gcagtcattg aaccgccacc taaatcatca cttaattttg ctgcacgttc caataagcgt
     3841 gagtgtaagt agaaaacatc ccctggataa gcttcacgac ctggtggacg gcgaagcagc
     3901 aaggaaagtt cacgataagc aacagcttgt tttgaaagat catcaaaaat gatcaagaca
     3961 tgtttcccgt tgtacatgaa ctcttcaccc attgcagtac cagcatatgg tgcgatataa
     4021 agcaacggcg ctggttgaga cgcaccggca ttcacaacga ttgtgtaatc cattgcgcca
     4081 tattttttca atgtttcaac ttgtgtacga actgtagaat ctttttgtcc gattgctaca
     4141 tagatacaga tcatatcttg acctttttgg ttgatgatcg tatcgatcgc aatggaagtt
     4201 ttccctgttt tacggtcacc gataactaat tcacgttggc cgcgtccgat tggtacaaga
     4261 gcgtcgattg cttttagacc tgtttgcatt ggttcgttaa cagatttacg ttgcataacg
     4321 cctggtgcca ttgcttctac tggacgagct ttgtcagtaa cgatttcacc tagtccgtca
     4381 attggctgac ctagcggatt aactacccgt ccaatcaagg cctctccaac tggaacttcc
     4441 atgatctttc ctgttcgttt tactttatct ccttcacgaa tggactcgaa atcgccaagg
     4501 ataatgatac ctacatcatt tgattctaag ttttgcgcca ttccgtatga gccatttgaa
     4561 aattcaagca actcaccact catcgcgttt tctaaaccat gtgcacgagc gatcccgtca
     4621 cctacataag ttacggtacc gatttcttcg actgaaagca cgttttgata attttcaatt
     4681 tgttctttaa tcaaggcact aatttcttct gctttgatgg ccattcgatt cacctacctc
     4741 tttgtactat ctatttaatt gattacgcat attttctaat tgcgtgcgaa tgcttccgtc
     4801 gattactcga tggttagctt caacaatcgc gccaccaata atagaagaat caacgatttg
     4861 ttttaattcg actgattgat agttcattgt ttttgcaaca ttcttttcta attgtattcg
     4921 ttgttcgtct gaaagtggaa ctgctgttgt gacacttccc aacagcaaac cttgatgttc
     4981 atcatatcga cgttcatatt cttcgatcat gaacaaaaga tcatccattc ggttatacgc
     5041 ataaacaact tctaaaaagt ttttaacgat tccatcatag ccactaacaa gcttgtccat
     5101 gatttctcgt ttttcatgag gttctagacg aacatcactt aacatattac ctaatccagg
     5161 tacttgttca tagatttgac gtaagcttac gagatcttga taaatttctt ctgctttatt
     5221 tgaatcgatc gccagttcaa ataaagcttt cccgtaacgt cttcctactg tatatttatc
     5281 tagtttcatt tgaagaacct agaccttcga tatattgatt gattaatgat tcgtgcattt
     5341 ctggagataa ttctttgttc aagatttttt ccgcgatttg aagagatagt tctgcaacat
     5401 cgtcttttac agagttcagc gctgaatcac gttctacagt gatatcagct tgggctttac
     5461 tttttagacg agctgcttct tcttgagcat ccttcaaaat attttggcgg cttaattctc
     5521 cactttcttt cgcatttttg atgatatcag ctgcatcaga acgagaggct aacaattgtt
     5581 gttcgcgttc ttgttccatt ttcgctgagt tgatgcgaga ttgttctgca gaatccaaat
     5641 cattggcgat cttgtcttca cgttttttca aaatatcgct gattggtccc caagcaaaat
     5701 gcttcaagag agccagtagt atcaaaaatg agccgctgac aacgatgaca tttcctaaca
     5761 tcgcattgcc aacttctgca attgccaatt gattcagcat aggcgagcct tcctttcttt
     5821 gaagtacttc tagttttcat gtaaaaaagc agtaacaaac caaattgttt ctgccttaat
     5881 actgattcaa ttaaacacca aaaactagaa tcaaggcgac aactacccct aagataggaa
     5941 cagcttcgac tagagctacc ccgataaaca ttgttgtacg gaattgacca gacatttcag
     6001 gttggcgagc cattgattcg attgttttag agataacttg accgttacca taaccggctc
     6061 cgattgctgc tcccatgatt gcgattgctg ctgcgatata attcataatt gttttcctcc
     6121 taaattagat aaatagtagt ttgtttttaa aacgaatatt attcttccac ttcaatctta
     6181 tggctcatat aaaccataga taaagtaacg aagacaaatg cttggatgct tccgataaac
     6241 aaggagaatg cgatccagac catctctaat ggaattgcta acggcaatga gaaccagcct
     6301 aagcttatta ccatttttgc aatcaaggtt agcaaaactt cccccgcata aatattccca
     6361 taaagacgta aagcaagtgt taataagttt gtaaattctt caatcagttt catcggaaac
     6421 ataaaactat atggtttcaa gaacgaattt acgaaatatc ctttgaagcc taactttttc
     6481 accccaaata agtgagtaag taagatcatt ataaatgcca aagttaaagt aacaaacggg
     6541 tctgctgtcg ggcttttcca aagtgttgtt tcgttaggta aaacgatttt tgttactaaa
     6601 ccgatgttgt ttgcaacaaa aacaaataaa aacaatgtaa atgccaacaa atggaaattg
     6661 ctcaattctt ttctaggcag attatctgtt acgattcctc gactaaaatc aatgacccat
     6721 tctatcgcat tttgtttgcc tgttggtttc aacttaagat ttcttgtaaa aaagtaagct
     6781 aagaagaaaa caatcaaaca ggtcagtaac accattatac aaactgtacc atcaaaccaa
     6841 attggtccaa tgtggaacgt tagcgagcgt tcatccaatc catttcacct cttttccccg
     6901 aaattcacat aaaatcaatt catgtgcgta tctggttttt tccaatcggt ttctaaccac
     6961 acggtatcat accaccatga aacagaaaat tcaaaacatt ttcatgaaaa ttagacactt
     7021 ttttatttca gtcaaaaacg aagcgaattt ttctttatac acggtgctcc tgatctaaga
     7081 aaaaacctat gataatcatg ttttatcaga ttaaatgcta acaaatttta tcattaagta
     7141 aaagcaaaag caccgaatat gcgaaaaagg ataatgaaat tatctagaga aattttttaa
     7201 tgttcgatca atttgtcgat cgatatcttt tcgtttcaaa tcttcccgtt tatcataaga
     7261 ttttttccct ttcgccagac caatcaatac cttggcatag ccgttacgaa tatagacttt
     7321 taaaggaaca acagtgattc cagtattttt caattcattt tcaagccgga tgatttgttt
     7381 tttgtgtaat aataactttc tcgtgcgcaa cggatcatga ttaaaaatat ttccttgttc
     7441 ataaggactg atatgaacat tatgcaagaa agcttctccg ttgcggacgc gaataaatcc
     7501 atcttttaga ttgatccggc tgtttcgtat cgacttgatc tcggttcctt gcaagaccat
     7561 ccctgcttcc atcgtgtcga tgatcgaata atcatggcga gctttcttgt tttgtgcaat
     7621 taattttccc tcgccttttg gcatagctgt ttcctccaac tcattttatt ttttcttttt
     7681 cttcttttta acacctttgt aaaatggctt cttccctttt ttcttaccga acgtttgctt
     7741 actatcgcta tatcgtttgt tcttcttgcc atttctttct gggcgttttc ctgcttgttt
     7801 tccttcgcgt tttcctgatt ttccatttcg tgtttttggc cgttccaacg ctgtaacctc
     7861 ttctgcggaa acaagttcaa aatctactgc tcgttcatct ggatcagctt tgactacttt
     7921 tactcgcact ttctgtccga ttttaaaagt cagaccagtt ctttcaccta caagagctaa
     7981 atgattttca acaaaatgga agtagtcctg tttcaattca ttgatatgga tcaatccctc
     8041 tactgtattc ggcagttcga taaacaggcc gaatttcaca acagagctga tgatcccatc
     8101 gaattcttcc cccactttgt ccatcatgaa ttctgctttc ttcatggaat ctacttcacg
     8161 ttctgtttct actgcacgac gttccatctt agaactatga tctgcaattt caggaagttc
     8221 cgtagcccac gaactttgat tgctttcact tttatcttca ctgtaagaac ggatcagacg
     8281 atggacgatt agatcgggat agcgtcgaat aggagatgta aagtgtgtgt agtaatctgc
     8341 cgctaagcca taatgcccaa aattgtcttc tgaatagcgt gcttgttgca tgcttcttag
     8401 caacatagta ttgataactg cagcttctgg tttgtcttct actccttcga tcacatgctg
     8461 taaatctttt ggtgtgatcg ttcctttcgt tcctcggacc agaatgccca aagctgaagc
     8521 aaaatcaaag aagcgctgca ttttttcttc ttttggctgt tcatggattc ggtaaataaa
     8581 cggcagattt aatttattat aatgttcagc taccgtttca ttggccgcaa gcatgaaaga
     8641 ttcgatcaag cgttcaccaa ttcctctgct tcttagctgg atatcatttg ggtgtccttc
     8701 agcatcaaca aggatttttg cttcgcgatc ctcaaaagaa atcgcgccac gtttgattcg
     8761 catcgtttca aggattcgat gcaattcacc catttcttgg aacataggta cgagctgagc
     8821 atagcgttgc atcgtttctt cgtcttgatc ttctaagatt tgattgacag ctgtgtaggt
     8881 catccgttct gttgtttgga tcacacttgg gaaaatatca tgagagacta cttgtccatt
     8941 tggatcaatc tccatttcgc aactcatggt cagccttgga acatggggat tcagtgaaca
     9001 gataccattc gataaacgtt gcgggatcat cggaatcact cgatcagtca aatatacact
     9061 tgtccctctt tcatatgctt ctctgtccaa ttgactgcct tgtgtcacat agtaagaaac
     9121 atctgcaatg tgtactccaa gaaaataatt accgttatct aattttttaa ccgtaactgc
     9181 atcatctaga tcttttgcat cttctccatc aatcgtaaca atgagctgat ttcttaaatc
     9241 tctacgtcca gttatatcct tttcgctgat ttgatctgga acttcatctg cttcagacaa
     9301 tacatcatca ggaaatttcg tagggatacc attagccacg acaattgaga ggatatccat
     9361 gccagggtca ttcttatgac caatcacttg cttgattatc ccttctaaac tagtcgcata
     9421 ccctttttca gggtaatggg tcagttcgat cagcacaata cttccgtcaa ctggacgaac
     9481 tccctctgct gctgcatata ctttaaattg gttgagcttt ctatctttcg ggataacaac
     9541 gccgtaaaga tccgtttctt gtatttcttc ttctgaataa gcaacgaatt cccctgctaa
     9601 ctgagtagtc gcccggtctc gaatctcgac tactttcccc tctgctccgc gatccatatc
     9661 tgtatttgct cgcttcatga tatcgattgc tacggtgtct ccatccattg caaaaccagt
     9721 cgcttctttt gggatataga tgtcatcttc ttcgggatca atcgttacaa atccaaatcc
     9781 tcgttcattt gctcgaaatg ttccttcgat caagattggt tttaaaggaa gtttcacttt
     9841 tcctttttta ttgaaaacta tactctgttc tctttccatt tgagcaatcg tttgtactag
     9901 taatttaaaa tcatcgcttt tttggaaccc taaaccttca gcgatttctt ccatagaaaa
     9961 actgcgtttg cgactgcttt ccatgaaaaa gagaattttc tcttttatcg tttcttttgt
    10021 catatttatt cctcattcca aggtaatttt tctaaaaatt ccaagacgtc tttttctaat
    10081 tcgcgtcttg ctgtaccaac tgtaatcaca tgaccacttt caggatacca tcgaagtgtc
    10141 actcgctgac ggctcaactt gcgtgcagtt tcaaatacgc cattagggtc gatcatttca
    10201 tctttcccag cttgagctaa aaatatcggc tgttggatat ctgacaacct actttctacg
    10261 attgctgcct gatcttgtat atccattaat tgttgttcag ctaacgagcg gtaagcaact
    10321 gctttttcat tgatttcttt ctctgattta cctgctgtct tcagcacttg acgtacgtat
    10381 ttttcaaagt tttcaggcac gtttgttttt acaggagaca aaggcgaaca gaaaaaaccg
    10441 ccgccaatca ctgattcttc ttctagtgct cgtacagcaa agatgccgcc cattgataat
    10501 cctaatacgg caatatcaga aaactgctca gactgtaaaa aatggatggc ttttttagtg
    10561 tctgcccacc agctttctgc tttttcttgc aaaatatcat atggctccat tgttccgtgt
    10621 cctttaaaaa gcggcgcata aactgtataa tctgcttttt ccaaaaatcg tgcgagcatt
    10681 cgaacatcgt ttggacttcc tgagtaagcg tgaagcagca aaaccgctcg ctttccatgt
    10741 tttgcataaa ggggttttgg taattgtctc actcgtctca cctctttcgc ctcattttac
    10801 catagtttct ttcataactt cttcttaagc gttctctttg caataaaaaa agccgcccgc
    10861 cgttttgcga gaggcttatt caactacttc gaagataaat atgctaggac aaataataag
    10921 atcatccaga tagctcccat aactgcagtt gatcgctgca tgacagcttc aaagccgcga
    10981 gctttttgtt tgccgaatag ttgatccgca ccgccggtaa atgcactcgc tgcactattt
    11041 tgcttgcttg gctgcatcat aatcgcaatg accataacaa tcgataaaac gatcacgatt
    11101 cccaaaatta aattatacat atcgcagcct ccttcccaaa agatatcgtc tctttaactt
    11161 tatcatagat aaaagtccgt gacaactcta tataaatgga ataacagctg aaagttcaaa
    11221 actttcagct gttattctta tgactgacgt aagacgtctt gatattctgg tttcttttca
    11281 aactcttttt ttgcataagg gcataaagga atgatctttt tcccgtctcg tcttgctaat
    11341 tctactccag tatacactag cttttcagct aacttttgac cacgatatgc tggatctaca
    11401 aatgtatggt caatgatcat gatgtctggg cccgcatctg accatgtcat ttctccgatc
    11461 tcttgttgtt catcattgaa taaagcaaga cgattttttt cttctttgat ttccatatgc
    11521 cgcactcctc aaataactga tattttttta ttcctacctt attttagcag tctcctgatc
    11581 tataaacaat tatttatcct cgaattactt acaaaaaaga agagaaaatt aattcatcgt
    11641 tattctttgt tcaataaatg aaaaaatcac tgtccaatag gttttcggat ctttcatcga
    11701 tgcttccaag tgttctgctt ctggaacaag cagcagtgct ttatcccctg ccgtagcatt
    11761 ttgaatcgtg tacgctgctt ctgtagggac aaaatgatct ctttcaccat gaatgaccaa
    11821 taaaggcaga tggttgctgc caagctgtct cgtagctgat gcttgcttta aggagtaacc
    11881 ggcgtatttc tgggcataat gattcgcata tctcatgacc atttttttag gaaagacagt
    11941 gattttactt aacatatatc ggaattctgc ataaacagaa acatatccgc tgtctaaaat
    12001 aaatcctttg accgctgatg gaagtttttc accacttgcc atcatgatcg tagaagctcc
    12061 cattgatccg ccgtgtaaaa taatggacgc attcggctgt tcatctaaga tgagttggat
    12121 ccaggcaatt aaatctagcc gatctagcca tcccattccg atgatttctc cttcactttc
    12181 tccgtgcgca cgtaaatcag gtacaagaac gttgaatcct ttctctgcat atcttttacc
    12241 tatatgagac atgtctcttt tccctgtgct tcggtaatca tgtacgcaaa tgacccattt
    12301 attctgctta tttggatgga tgaacatctg accagctagt ttcaacccgt cataactttt
    12361 gattgttttg ggtgttccct gctcccaaaa gctttcacac tcttcttcta atttttgtcg
    12421 ttttttttct actgacgtga ctgcagcagg gtccatcaaa cgatgaccag tgtcttcata
    12481 ccagtcatat cctctctgta ctcccgctct tactaatttc tttgcataaa aataagaaag
    12541 aaaatggtaa ctgatcccta taattatcag aataagaatg aaataaaaaa taaccattgt
    12601 acacccgccg ctttctgcca aactataatc taactattat ccaatgtacc gatccatagg
    12661 attctttatt ttcggcacac gtaaattcca tttctttttc attgtatcat ttacttaaag
    12721 ttctcctcaa tagatttact tgtaagagag catttacatt cgcaataaaa gccagtatac
    12781 taatttcgtg cattataatc aagacgctcg tcttggactg gttcggaaac ttcccagaat
    12841 aaaaaactaa gtatctctaa agaaaggaga ttggaaataa tgcgaaaagt aattattgat
    12901 tgcgatccag ggatcgacga cactttagct ttatcattag ctgtcaaatc ccctgatatc
    12961 gaagtagttg ctattaccgt agtttgtggg aatgtccctg cagatatagg tacgcagaat
    13021 gtgctgaaat gcctggaacg ctgtgatcgt ttagacattc ctgtttatca aggaatggaa
    13081 aaacctttga agcaaccttt catcagtgca caagacactc atggtatgga tggtttaggg
    13141 gaaacaaatt tcccgatgat cttgagaaaa caggcagaac ctctccatgc cgttgatttt
    13201 ttggctgatt atttcaaaga aaagacaaat acatcagtca ttgctttggg tcctttgacc
    13261 aatatcgctt ttgctttgaa agtcaaccca aatattggga aacatatgga tcgttttgtc
    13321 tcgatgggtg gaacttacaa aagccatggt aactgttcgc cagttgctga atacaattac
    13381 tggtgtgatc ctgaagcagc ttcttatgta ttcgagaatc tcaaacaaac gatagaaatg
    13441 gttgggttag atgtgacaag agaaatcgtc ttgacaccga ctatcctcga atactgctgt
    13501 caaatgaatc ctgaagaggg agagtatcta aaagcgatca ctcgttttta ttttgacttc
    13561 cactggaaac aagaaagaat tttaggatgt gtcatcaatg atccgttagc tgttgcttat
    13621 tttatcgagg gggccatctg tgaaggtttc aaaagcttca ctgctgtgga aactcaagga
    13681 ataagtcgtg gacaaacatt ggttgatcgt tatgaatttt ggcagaaacc tgctaacagt
    13741 aaaattatga caaaagtaga tactcgtctt tttttccgaa agtttttaac cgttctttta
    13801 aatgcacaag aagaaacgat tatgaaagat ttggaaaggt taaagatggg ctaacaaaat
    13861 gaataaaaac aaaatggcaa ctcgcgtact tacagtgatg gctttgtgta ttgggatcaa
    13921 ttatattgga ggaacgattg ctttatggct tcgtttgcca atctatctcg attctatcgg
    13981 aacgattttt gctggtgcat tgcttgggcc tgtacctgga atgctgacag gattgtccag
    14041 cggtatttta agtggagtga ctacagatat tttttctctg tattattcgc caatccaaat
    14101 tctcacaggc ttgcttgctg gattgatttt gccaagatat ctcggcaaag ataaaaacag
    14161 cttgaaactg ttattactcg ctttgatttt gtcggtacct ggaacgatcg tttcttcgat
    14221 cattaccgtt cagttatttg gcgggatcac ctcctcagga tccagtatga tcgttcagct
    14281 attacatggg ttaggtttaa gtcagacaac aagtgtgatc ttggtacagg caggtacaga
    14341 ctaccttgat cgtttgttgt ctatcgtcgt tgtttcatta gtcatcacta tgttgccaca
    14401 acgcttgata tattcaaaaa gaaaaatagg ctgaataaac agagctggat tagcaaaata
    14461 atgctaatct ggctctgttt tttcatttat taaaaaaatc ttacgctaag taggataaaa
    14521 taattccttg atatttttca atcatatcca aataattatc gatttcaaca tactcatcta
    14581 cttgatgagg caaagtaacg acaccaggcc caaagacgac aaagtcgaag gaatggttag
    14641 ctttcgtaaa ttcggctgca tccgttgttg ctgccgctcc aactaaaggt aatggctggc
    14701 tgaattgttg ctgaatgcaa tgaatcaaag gagaatctgg atcagctttg acaggtattt
    14761 tgttgtaatc gatcatcaat tccaaatgat agtctgtctc ttgattcaat tcattgacga
    14821 ttgattgcag caatgcaatg attttatcat ttgggtattc tggaatcgat cgaatgttcc
    14881 cttggagctg cgcatggctt gggatgctgt tgacttgatt cccgccactg atcaatgtaa
    14941 cattatggat tgtttttcct aggacaggat tctcgattgt ttcagcgagg tgattcattt
    15001 cagcatttgc tttcgtaatg aattcattta ggtgattgat tgcattataa ccttggtctg
    15061 gcatagagct atgcgcttct tttccgtgcg aggtgactgt atagttgatt gatcccatgt
    15121 gcgtatacat caaactgtaa ttagttggct ctccgatgat caaggcatct aagtcatcta
    15181 catagcctgc tttcgtgagc tgttccccac ctagttcacc cacttcttct ccgacagtgg
    15241 ctaataattt gactgttccg ttaaatggtt ttcctgactc tttcagttcg atcatggcaa
    15301 tcaccattgc tgccaagcca ctcttcatat ctgtagcacc acgtccgtac aaacggttcc
    15361 catggatttc tgctgcaaag ggtgcatagg tccaagacga ttcatcacca gccgccacga
    15421 catccatatg cccagatagg cctaacactt ttcctgattg gcccttttgg taacgagcaa
    15481 tcaaattatc tctaccatct ctgtaagaaa caatctctcc tgttatgtca tgctttgcca
    15541 aaagcttatt caaataggct gctacttcac cttcgtttcc attcactgat ttaattcgga
    15601 tgatctcttg taaaatcgcg attttttctt cttttttcat ctaatcctct cccttgccat
    15661 ttctttttat tgtatttgag tgtgctcgaa ttttcaaata ggagcaacca aagtaaaaat
    15721 gaagaaagag agccacttta tgaaaaatat gctgctactt ccctcctatt ttatttatac
    15781 gagaggactt gctcatagat tcctattcta ctgttctatc cttaaaagct cttatatgat
    15841 gctagttatt gttagctttc ctttttcaag gatgatcttt tcttgtacca ttctttgtaa
    15901 acatcatata cagaagctag ttgcaaaaaa aactctctac ctgctgatat
//
LOCUS       DACGDM010000054        15752 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.055, whole genome shotgun sequence.
ACCESSION   DACGDM010000054 DACGDM010000000
VERSION     DACGDM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.055"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            138..1475
                     /locus_tag="IXR05_001844"
     CDS             138..1475
                     /locus_tag="IXR05_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAQ4260337.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            1523..3652
                     /locus_tag="IXR05_001845"
     CDS             1523..3652
                     /locus_tag="IXR05_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAQ4260338.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3627..4316
                     /locus_tag="IXR05_001846"
     CDS             3627..4316
                     /locus_tag="IXR05_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260339.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(4724..5410)
                     /locus_tag="IXR05_001847"
                     /pseudo
     CDS             complement(4724..5410)
                     /locus_tag="IXR05_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(5546..5740)
                     /locus_tag="IXR05_001848"
     CDS             complement(5546..5740)
                     /locus_tag="IXR05_001848"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260340.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5790..6230)
                     /locus_tag="IXR05_001849"
     CDS             complement(5790..6230)
                     /locus_tag="IXR05_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAQ4260341.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(6234..7079)
                     /locus_tag="IXR05_001850"
     CDS             complement(6234..7079)
                     /locus_tag="IXR05_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAQ4260342.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            7228..8646
                     /gene="pepV"
                     /locus_tag="IXR05_001851"
     CDS             7228..8646
                     /gene="pepV"
                     /locus_tag="IXR05_001851"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAQ4260343.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(8703..9650)
                     /locus_tag="IXR05_001852"
     CDS             complement(8703..9650)
                     /locus_tag="IXR05_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4260344.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(9873..10223)
                     /locus_tag="IXR05_001853"
     CDS             complement(9873..10223)
                     /locus_tag="IXR05_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4260345.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            10423..11502
                     /gene="pepA"
                     /locus_tag="IXR05_001854"
     CDS             10423..11502
                     /gene="pepA"
                     /locus_tag="IXR05_001854"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAQ4260346.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            11646..11966
                     /locus_tag="IXR05_001855"
     CDS             11646..11966
                     /locus_tag="IXR05_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4260347.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            11988..12452
                     /locus_tag="IXR05_001856"
     CDS             11988..12452
                     /locus_tag="IXR05_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4260348.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            12657..13262
                     /locus_tag="IXR05_001857"
     CDS             12657..13262
                     /locus_tag="IXR05_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAQ4260349.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(13301..14590)
                     /locus_tag="IXR05_001858"
     CDS             complement(13301..14590)
                     /locus_tag="IXR05_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4260350.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            15018..15497
                     /gene="rlmH"
                     /locus_tag="IXR05_001859"
     CDS             15018..15497
                     /gene="rlmH"
                     /locus_tag="IXR05_001859"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAQ4260351.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT         4951 a         2915 c         3225 g         4661 t
ORIGIN      
        1 cataattaag gttttttaat tgaaaactga acatttatgg tcacccttta atgaaagcgc
       61 taactacata agttagaatg agtttgactg atatattagt ttgcttatca gaaaaacaaa
      121 atggacggag gaataacatg agtgatatta ttattggtat tttgttagtt atctcattct
      181 ttttcatggt ctggtactgt gtaaaaggct acaacttgat ggtcggcttt gccatcatgg
      241 ctactgtatg gatgggatta gcgctagtcg gaaacacgtt ttcaccaaac ccggcgatgg
      301 aagggcaagg agtaattgat gtgttgacgc atatctatac gacggggcca gctgagtacg
      361 ccaaatcgat cttggtaaat gtcttctttg gtgccttttt cgggcgtgtt ctagtagata
      421 gcggaatcgc agctaccctg attcgaaagg tagttgaact tggaggggac aagccaagaa
      481 tcacgatgag cttactatgt attgtaaccg ctgttatatt catgtcgatg acaggaatcg
      541 gaccagtgat ttctattgca gttattgtgt tgccaatctt gatgtcatta ggtatttcag
      601 taccggttgc actgttctca tttatgggct cgattatggc tggaatcttt gctaatatcg
      661 tcaatttcaa acaatatcaa acgatttatg ctggtttcaa tccagcggct gaaagctata
      721 cttataatga ctatttccaa attggtatga ttgggatgat tgtaagctta gttgtggtac
      781 taacggtcgc taatatatca atgaacaaaa agaaacgcta tgcaatggca gcaaacgtac
      841 cagctgaagg tggcgacgca ccaatgatct catggttagc cgtattatta ccagttttag
      901 gggtcgttct tttagatctt ccaatcatct taggttttat tctagcaggt atctgggcat
      961 tgctgtttac tggaaaattg cgcggaggtt ataaagaaat ctgtcgtcag tttgcgaaat
     1021 tatttacaga tggcgcagta gatgttgcgc caatggttgg tttcttgatg accttagcga
     1081 tgttcaataa ttcagctgcg tatgcttctc cttatttttc agctattttt ggagattgga
     1141 taccgcaatc accattagtc ttggcaatcg tatttgctat attgacacca ctaggatttt
     1201 tccgcggtcc aatgaatcta gtcggttcag gctcagctat tttagctgtc gtattagctg
     1261 ttaatccaac gatgtcgcca gcctttttgt tcccgttatt tgcaatcaca acgattgctc
     1321 ctcagcattt agatattaca caatcttggg ttgcttgggg attaggttat acaaaagtaa
     1381 cttctcgaga atatatgaag aaatccatcc caactggttg gatcatcgga gcgatcttat
     1441 gcctgatcac gttcttattg tacgggaacg cctagtaaac aaaacgtcga taaaaacgat
     1501 tagatgaatg gaggaaaaga aaatgaaacg ttttgtgcga atgggaattg atgttggcgg
     1561 tacacatacg aaagcagtcg caatcgataa tgcgacgcac gaaatcatcg gaaaatcttc
     1621 agtgaaaaca acccacgatg atgtccgtgg agtagccgca ggtgtcgttc agtcttttca
     1681 aaattgtttg ctggaaaata atatcagtcc agaagatgtt gtgtttgttg cacattctac
     1741 cacacaagcg actaatgcac tgattgaagg agacgtagca aaagtcggcg taatcgggat
     1801 ggcaaaaggt ggattagaag gttttttagc aaaacgacaa actagattga acgatatcga
     1861 tttagggaat aagaaaaaaa tagagattgt caatgcattc ttacctgtca aacacttaaa
     1921 tgtagaccgt gtttcagaaa cgatttcttc tttagaaaga gaaagagcgg aggtcttggt
     1981 ttcttctatg gcatttggag tagataatgg ggaaccagaa cgagttgttt atgaagcagc
     2041 atcggtaaaa tcgatcccta caacgatggc ttctgacatc acaaaattat atggattgac
     2101 aagaagaact cggacagcag caatcaatgc atctatttta ccaaaaatgc tagatacggc
     2161 aacctctaca gaagattccg tacgagaagc aggggtcaat gtttctttga tgattatgcg
     2221 cggagacggc ggagtaatgg aaatcaatga aatgaaaaaa cgacctgttt taaccatgct
     2281 ttccggtcca gcagcatcag tcatgggctc tttgatgtac ttgagagcgt ctaatggtgt
     2341 ttattttgaa gtaggcggaa caacaaccaa tatcggggtc attaaaaatg gacgtccagc
     2401 aatcgattat tcaattgtag gtggccaccc aacatatatc tcttcattag atgttcgggt
     2461 tctaggtgtg gcaggcggtt cgatggtacg ggctaatcag tcaggaatca tcgatgtcgg
     2521 tccacgttct gcacatattg ccggtctaga ttatgcagta tttacggaga cagaaaaaat
     2581 caaaggtcct aaggttgaat ttttctctcc taaagaagga gaccctgctg attacgtcaa
     2641 ggtagtgatg gaagacggag aagaagtgac tattacaaat acatgtgcag ccaatgtcct
     2701 tggattagtg caagaagaac atttttctta tggaaatgtc ccatctgcac gaaaagccat
     2761 ccaagcatta gctgattatt gtcatacgac ggttgaagac atcgcagaac agatcatgga
     2821 aaaatcctat gctaagattg aaccggtgat tttagaattg gcagacaagt atcacttgga
     2881 gaaagatcag atttctcttg taggtgtagg gggcggcgct gcctcattga ttacttactt
     2941 tagtaataaa atgggtgtga aatattcgat tcctgaaaac gccgaagtga tttcttctat
     3001 tggtgtagca cttgcaatgg tccgagatgt tgtagaacgt atcatccctt cgccaagtaa
     3061 agaagatata cgatcgttga aaaatgaagc gatgaataaa gcgattgaat caggcgctac
     3121 accagaatcg atcgaagtcc acgtagaaat cgatccacag acttcaaaag taacggctat
     3181 cgctactggt tctacggaag tgaaagcaac cgatctaacc aaggagatca caacagaaga
     3241 agcactagag cttgctgcag aggatatgcg attaaataaa aatgaagttt gcttattgga
     3301 aaatacacct ttcttttatg tatgcggcga acagaatcgt tcaaaaaatg ctggaagtct
     3361 tcggatcatc gatcaaaaag gatttatcaa ggtccaacgt ggacatgctt catgtatgaa
     3421 aacaactgca gccaattata tgacagctgt cgaacaactt tgggaagata tggcagttta
     3481 tcaaactgaa ttgattgccc gaccagaatt ttatctctgc ttaggagcaa gagtctctga
     3541 ttttacagcg acggatctgg aacaactaca gcttttgatg gatctggaag tatctactat
     3601 ggaaccggag gaagaagtga tcgtcgttgc cggaaatatc aaacaaacat aagttagaag
     3661 agttactaaa cgaattacaa cagatccccg aagaaatttg gggattctac cagtttcggc
     3721 gagatttatt ttggaaaaag attcctttgt ccaagcagaa aattcttata caacaatcaa
     3781 tcgattgtgg tatcgaaacg gcatgtagca tcaaaaaaaa gtaccctttt gccgatgtag
     3841 gagaaatttg tgaacaaatg gctgttccaa tcgtttcctg tgaatcagag caaataaacg
     3901 aacgaatcac ttttgcaact tatgcagaag atgaagggat tcgattgatg acggagccgt
     3961 tagaaaaatt aaaatgttca ggactagctt cgatctctaa agaaacagcg caagctttga
     4021 ttattggaca tgaactattt caccacatcg aagcttctgt taagggaatt tatacgcaaa
     4081 gcgaaaaaat tgtgctgtgg cggttgcctt tttatacaca tcaatcaaac attcgtgcat
     4141 tgagcgagat agcagcgatg agtttttcaa aagagatgaa tcaaagcgat ttttcgcctt
     4201 atgtattaga ggcagtctta ctttggccat ataatgaaat tcgtagccaa gggatcttag
     4261 aagaaataaa aaaaatagaa aaaagatgta cggagtatga tttagattac aaataaagag
     4321 actgtgacaa aagtcgtgtc acagtccttt ttttccgaat aaacggtgtt ctcctgtcaa
     4381 ctcctcggtc acaagtcaaa atattcaaca aacatgagaa gctgtttttt gaaattgttc
     4441 cttgtgactc ggagatgaac ggcaggctca cgacctcttg gaaaacggtg ttcaaaagct
     4501 tgcatctgcg gtaataagtc cagccaagtt aaaaacataa gaagctattt ttacttggct
     4561 gttcttatta cttgatgcag ggcagctttt tcacaacctc tcaataaacg gtgtgcaatc
     4621 agctgaccct cggtattagc tcaaaaaaaa cggcaaaata tgaggaacta ttttgccgtt
     4681 tctttctcta atactcaggt caaaacgctg attccaaaac ctcttatttg atgggtctgt
     4741 cctgaatatc ttcaaaataa tcggggtaat tatgaatcac gtattcttgc tcctcgataa
     4801 tcatatgtaa atgcatcgtg caaagaaatc cgacttcatc aaagttatga tcaatcattg
     4861 attgaagcat tgtctgatgt tcatctaata ctcgacccca gtctaattct gaaatcgtca
     4921 aacgtaacca tctgaaacgg ttcaagtgcg tactataact ttctagccaa tcccaaattt
     4981 ctcgttttcc agcaatttca taacaagttc ggtgaaaatc agtatccaaa tcaaaaaaag
     5041 cttttttatt ttgagcgatt actgcctgat cggtttgttc tagtattttt tctagtttag
     5101 cttgatctta cttggtcatt ttcgcactgc attcttgcag gatcggtttt tccaactttt
     5161 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
     5221 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
     5281 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
     5341 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
     5401 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
     5461 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
     5521 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttggatc ggtttgacac
     5581 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
     5641 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
     5701 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
     5761 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
     5821 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
     5881 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
     5941 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
     6001 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
     6061 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
     6121 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
     6181 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
     6241 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
     6301 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
     6361 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
     6421 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
     6481 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
     6541 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
     6601 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
     6661 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
     6721 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
     6781 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
     6841 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
     6901 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
     6961 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
     7021 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
     7081 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
     7141 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
     7201 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
     7261 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
     7321 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
     7381 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
     7441 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
     7501 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
     7561 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
     7621 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
     7681 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
     7741 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
     7801 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
     7861 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
     7921 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
     7981 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
     8041 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
     8101 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
     8161 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
     8221 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
     8281 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
     8341 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
     8401 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
     8461 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
     8521 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
     8581 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
     8641 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
     8701 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
     8761 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
     8821 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
     8881 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
     8941 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
     9001 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
     9061 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
     9121 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
     9181 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
     9241 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
     9301 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
     9361 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
     9421 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
     9481 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
     9541 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
     9601 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
     9661 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
     9721 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
     9781 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
     9841 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
     9901 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
     9961 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    10021 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    10081 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    10141 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    10201 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    10261 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    10321 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    10381 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    10441 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    10501 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    10561 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    10621 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    10681 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    10741 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    10801 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    10861 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    10921 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    10981 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    11041 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    11101 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    11161 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    11221 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    11281 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    11341 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    11401 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    11461 ttggataaat caacagtaaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    11521 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    11581 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    11641 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    11701 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    11761 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    11821 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    11881 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    11941 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    12001 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    12061 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    12121 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    12181 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    12241 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    12301 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    12361 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    12421 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    12481 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    12541 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    12601 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    12661 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    12721 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    12781 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    12841 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    12901 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    12961 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    13021 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    13081 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    13141 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    13201 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    13261 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    13321 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    13381 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    13441 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    13501 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    13561 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    13621 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    13681 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    13741 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    13801 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    13861 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    13921 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    13981 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    14041 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    14101 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    14161 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    14221 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    14281 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    14341 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    14401 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    14461 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    14521 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    14581 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    14641 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    14701 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    14761 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    14821 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    14881 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    14941 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    15001 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    15061 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    15121 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    15181 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    15241 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    15301 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    15361 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    15421 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    15481 ctccatacca caaataatga tattttttaa gagaaaaaat tatccctatt ttaaataata
    15541 gcaataggta gtggtaggga gaaatttata aataactttt ttatttgctt tggtagccaa
    15601 gtaagttgca aaagaaaaat agatactgtt aaaaagataa tgtagacata gaaacaaata
    15661 cgtaaaattt tagttagaat aatggcaagg agaaaaaaca tgatagatga aaaaaagtgt
    15721 ttaaaaaatc tattagagga tatggatgat at
//
LOCUS       DACGDM010000055        15716 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.056, whole genome shotgun sequence.
ACCESSION   DACGDM010000055 DACGDM010000000
VERSION     DACGDM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.056"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            72..1499
                     /locus_tag="IXR05_001860"
     CDS             72..1499
                     /locus_tag="IXR05_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4260352.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1591..1956)
                     /locus_tag="IXR05_001861"
     CDS             complement(1591..1956)
                     /locus_tag="IXR05_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4260353.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPLDVQNK"
     gene            complement(1953..2318)
                     /locus_tag="IXR05_001862"
     CDS             complement(1953..2318)
                     /locus_tag="IXR05_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4260354.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2510..2758)
                     /locus_tag="IXR05_001863"
     CDS             complement(2510..2758)
                     /locus_tag="IXR05_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260355.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2757..2885
                     /locus_tag="IXR05_001864"
     CDS             2757..2885
                     /locus_tag="IXR05_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAQ4260356.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2942..4636
                     /locus_tag="IXR05_001865"
     CDS             2942..4636
                     /locus_tag="IXR05_001865"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAQ4260357.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4736..4909
                     /locus_tag="IXR05_001866"
     CDS             4736..4909
                     /locus_tag="IXR05_001866"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260358.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5287..6420
                     /locus_tag="IXR05_001867"
     CDS             5287..6420
                     /locus_tag="IXR05_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAQ4260359.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6451..6771
                     /locus_tag="IXR05_001868"
     CDS             6451..6771
                     /locus_tag="IXR05_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260360.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6800..7264)
                     /locus_tag="IXR05_001869"
     CDS             complement(6800..7264)
                     /locus_tag="IXR05_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260361.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7396..8649)
                     /locus_tag="IXR05_001870"
     CDS             complement(7396..8649)
                     /locus_tag="IXR05_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260362.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8678..8995)
                     /locus_tag="IXR05_001871"
     CDS             complement(8678..8995)
                     /locus_tag="IXR05_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4260363.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIINLYRR
                     LNA"
     gene            complement(9021..9341)
                     /locus_tag="IXR05_001872"
     CDS             complement(9021..9341)
                     /locus_tag="IXR05_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4260364.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9805..11220)
                     /locus_tag="IXR05_001873"
     CDS             complement(9805..11220)
                     /locus_tag="IXR05_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4260365.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11237..12553)
                     /locus_tag="IXR05_001874"
     CDS             complement(11237..12553)
                     /locus_tag="IXR05_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260366.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12703..13401)
                     /locus_tag="IXR05_001875"
     CDS             complement(12703..13401)
                     /locus_tag="IXR05_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAQ4260367.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13690..14679)
                     /locus_tag="IXR05_001876"
     CDS             complement(13690..14679)
                     /locus_tag="IXR05_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAQ4260368.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14759..15592)
                     /gene="msrA"
                     /locus_tag="IXR05_001877"
     CDS             complement(14759..15592)
                     /gene="msrA"
                     /locus_tag="IXR05_001877"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4260369.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
BASE COUNT         4890 a         3185 c         2691 g         4950 t
ORIGIN      
        1 tgatttcaaa aagaaaacat gtcataatat ttcccatatt gtgcaaaaaa atacaaggcg
       61 gaggctctac tatgattgaa gaatatattg agaaaaatat tttaagacag ctgtttttat
      121 gtgggcaatt ctatgtaaat aaagaagtca atctagaaaa gctctccaat ctcctgcatg
      181 tttgcaaaac cactttactc aatgatatca ataacataaa aaaagaattt gaagaacaga
      241 tcgcttatac acatcgggaa aaggaccgtt acactttata tttttcagaa catatacctc
      301 gatgcaagat catgcagcaa ttgtctcaaa attcgttgtt tttaaaaact tgtctgcttt
      361 atttggaaga agatgaacct gattatcttc aattaactga atgtgaattc atctctgtca
      421 gcaaagctta ttcattaaaa aaacaagtat tagcttactt taatgactgc gggatcgaaa
      481 tcgaccgcta ctcccctcga ttcactgaaa tggaaagacg tctgctgctt cttaatgtgt
      541 cgtatcgttt aggcggtttt aattcttggg agctacctga atcgtttttt gaacgtgccg
      601 atcgtttcat tgaatccgta acggaaaata gtggcagatt ttatgataaa gaaaataaag
      661 aaatcttatc gattggtttt gctatcagtt tcctacgcca gcaagtgtgt gctgtgacaa
      721 tagattcaaa atttatcgaa gaaatcaaaa aacgtcctat ttacaattat gtcgaatcag
      781 catgggaaaa cactgatttc caaacctatt ataaaaaaga agaattcgcc tttattttga
      841 cactattcaa tctttgtaat tatggtttcc attcttatca gttgattgcg gaagactttc
      901 aacagctaca ccaagtgttt attgacaata ctcccgaaat aaaagaacta gttgctacct
      961 ttgaatctca cttcaatcaa gaattattcg gaaaccaacc gttcgaacgt gcgctgattc
     1021 atctgatgcg ttcggcttgg gataactatc aattattcat gccagaaaaa ttttatcttt
     1081 taaatgagga acagacaaat ttatataaag aagtccagac aattttttcc agctggtcca
     1141 gccagttacc ttatgatcta cggttgaatc ctaattgcat gcgggctttt gtgatcgaat
     1201 tgagcggaat tctccgtctg acaaaagaac atctgactat ctatatcgtc acaaattcgg
     1261 atgttcatta tctgatttat cgggaagcct tggaagctgt aactactttc gattttcaag
     1321 ttgcaccaac aatttattca agtatatctg atataaagaa gtatgcgcag cagtcctcaa
     1381 accgggtatt atgtgaacgt acattatata caccagatgc ggtccaatat gaaaatatta
     1441 ttcctatttc gatcaatacg atcgatcgag ctatcatttc agctgtgcaa aacaaataag
     1501 gggctgtgac aaaaatcatg tcacagcctc ttatttgttg aagatgccca tttctgtaac
     1561 aatctcttga tacacgtcag gctcacaacc tcacttattt tggacatcta ggggtccgat
     1621 ctctttattt aaaaaataag aaatgatggt tcggataact accaacgccg ctagttggaa
     1681 aatatcctgc aaggtaggtt tgataatcga ttcgatgatc ccagctgaaa caagaatttc
     1741 caaacttaga agtatatagc ctcccaacat ctttttaata gcattgttct cgcttactcg
     1801 gtcgctttgc acttttgtat ggacaaataa atatttcaaa aaatccttga ttgatagaca
     1861 aacaccccaa accaataaac agatagcaaa gatatcaagt cccagtacaa gtttttcgaa
     1921 atatggaaga agaaactgca tcaactctgt cgtcatccta cctctcctct tctttgtttt
     1981 tctttgtctt ctatttcctg attcaagaaa taagaaatga ctgttcgaat gataataata
     2041 agtgcaagct tcaaaatatc tgtccaagtc ggcttgataa ctgactcgat gatatcagca
     2101 acgactagta cttccaagct taacaaaata taacttgcta gcagttttct tgtatctgca
     2161 ttacgagtat tacgttctgc atagtttttc ttgacatgag accaatcaaa aagtttgaat
     2221 agaacaagaa cgatcccgac aattaagata ccgatagaac aaatatttaa aatagcaatg
     2281 atccattcta gaaattcaat taaatttgag cgaaacatat acgctaccta ctttctttta
     2341 atttgttcct attcttttat tgtaaaagaa agttaccttg ttcgtctatt taaaagttgt
     2401 tctaatgata acggttcgct taaatttttc tttttcactc tcccattttt ctccctccat
     2461 ccataaatcg tggaagtatc caaaacaacg tagcaagtta aaataaggct tagtccgtca
     2521 tcagcttttc aaagaagcac tgtctcggtg ctttttttgt acccaaattt ctaaaaatag
     2581 aaccatacac ctcctcaaat cttttcttct tacctaccct atttttattt acaggaaaat
     2641 cagacacttc ttcttttttg tcaaaatttc ctttttcttc tcgtcctatc atttggcatt
     2701 ctaataaaaa cgaactatcc ttggatatag aaagagaaaa caaggaggcg tttttcatga
     2761 gtaaaaaatt aatcaaagtc ggcatcggtt taggtttgct tgcccttggc gctgcatatc
     2821 taggaaaaaa gacaggacta ttcgaagatg acagtcattt atatgatgaa ttcgaatcaa
     2881 tctagcatcc tatttagttg aatcactacg gacatacttg gaagacattg gaggaatcac
     2941 aatgagaaaa agtaaagcaa taatgattgg tgccggtatt gccaatatgg cagcggctgt
     3001 ttatttgatt caagaaggca aatggaaagg ggatcagatc accttttatt cattggatga
     3061 tcacggttca aatgatggtg caccgaccga cactgtagtg gatgaatatt ggaataaaaa
     3121 ccatccatta gaaaaccaaa aaggctatat tgctcgaggc ggtcgcatgc ttaattaccg
     3181 tacctatgta gatttgatgg atctgttaag tcgaatacct tctgttactg agccagggat
     3241 gactgctgaa gaagatacga gagattttga tgcaaaacac cgaacctttg acaaagcacg
     3301 tttgatggaa ggtggcaaag gaatcattga tggcggaaaa ctgggattca ataataaaga
     3361 ccgtattctt ctgactaaac tgattgctat gcctgattca gaagaagaaa aactagacaa
     3421 tatcactatc gaagaatatt tcaaagatga tccacacttt tttgaaacaa acttctggtt
     3481 tatgtgggaa acaacatttg ctttcagaac acgtagttct gctcaagaat tgcgtcgcta
     3541 tatgcatcaa atgatttatg aattcactca aatcgaacat ctagtgggcg tcaatcgaac
     3601 acgttacaat caatacgaaa gtattatgct tcctttgatc gagtacttga aagaacaagg
     3661 atgcaaaatc attttgaacc gccgtgtcac tgactgggaa ttcaaagaaa caccgatgca
     3721 agatgaaatc actgtgactg gtttgaaaat taccaataca ctgactcaag aagaagaata
     3781 cgttgtggtc gatgaagata cagcagttat tttcactaat gggtccatta cagattcagc
     3841 tactttagga gattacgaaa caccagctgt agaaaatatg gattatggtg cagcttctag
     3901 tctctggaaa aaagccagtg aacgtttcta caacttggga aatcctgaca aattctttgc
     3961 tgatcgagat gcaagcgaat gggtcagctt taccctgacg acgaaaaacc atttgttgtt
     4021 gaatgaaatc acccgtatca cgactcaaga accaggaaat gccttgaatt catttatttc
     4081 aaccacaccg atcacgccgt taggccaaaa agatgtcaat atgtctattg tcgtgcatca
     4141 tcaaccgcat tttacgtctc agaaaccaaa tgaaacagtt atttggggtt atttccttta
     4201 tccaagacga cgtggcgaat ttgtggataa acagtatatt aaaatgaatg gaaaagaaat
     4261 gctagaagaa ctgattggac aactttcaaa agtagatcct ggaccagtga atattcgtga
     4321 aaaagaaaca gaaattttcg acagcgtaat aaataatatc cctgtctata tgccttatgc
     4381 ttccgcgttg ttcaataatc gtgccaaaag cgatcgacca aaagtcattc ctaaacattc
     4441 gaccaatctg gcctttacag gagaatttgt cgagcagcct tatcagatga tctttactga
     4501 acaaagtgct gtacgttctg gagaaatcgc tgctttccat tttgcgggta ttcctatgtc
     4561 ccgtcttgtc aaaacaccgc gttacgacaa agatattcct actctagctc gtgccgcaaa
     4621 aaaaatgttt gaataatcaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac
     4681 aaccaggcta aaacagcttc ttatgttttt gatttggttg gacttattac cgcagatgca
     4741 agcttttgaa caccgtttac caagaggtta tgaaaaagct gccctgcatc aagtaataag
     4801 agcagccaag ctaaaacagc ttcttatgtt tttgacttgg ttagacttat taccgcagat
     4861 gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa ggcgtttagt ttcgagtatg
     4921 aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat aaatttgact taataccgag
     4981 aaactgatcc cttctgtcat aacctctttt tatttatgtc tgtttctttt tgaaaacaac
     5041 tattttttca acgtttactc tcttgccaat ccaacatcat ctaacggata caactatttc
     5101 aatgattacc attacactaa aaaatcggaa acacacctct ccgaacacaa atacataaga
     5161 ctatagaatg tttcatttaa gaaaaaaagc gtttcattat caaaaaggta agatctcctt
     5221 taaaatgaaa ttatctgtag tactaataat gcagacaatt ttatgaatct gaaaggagca
     5281 tctccaatga aagcagtcac ttggcaagga aaacagaaaa tggaaatcag aaacgtagat
     5341 gatccaaaaa tattagaacc aacagatgca atcatccgta tcacagcaac agccatttgc
     5401 ggctccgatc tgcatcttta ccatcatggt gaagcagttt tggaaaaagg gtatgttgta
     5461 ggacacgaac caatgggaat cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa
     5521 gggcaacgtg tggttatccc ttttaatatt agttgtggtc attgtcattt ctgcctgaat
     5581 cacatggaaa gccaatgtga tgaatcaaat ccagatcagt tatatggcgg gcttttcgga
     5641 tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg aatatctaag agttccttat
     5701 gcagactcta cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa agttttattt
     5761 ctatcagata ttttgcccac agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc
     5821 gatacagttg tgattctagg ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt
     5881 atggctggag cagagcgcgt aatcgcagta gatccagtac agcaccgtct agataaagcg
     5941 gctaattaca atggggttga aacttatttc ttagaagaca cggcacaagc tggaacagaa
     6001 ttgtatgaac tggctaaagg tggcgcagat gtcattatcg attgtgtagg aatggacgga
     6061 ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct tacaaagcgg cacaatctct
     6121 ccattacaga tggcatcgca agctgtcaaa aaatttggaa cagtccaagt aactggtgtt
     6181 tatatgactc cagcttcttc ttacccgctg caagaatttt ttatgcggga tatcgctgtc
     6241 aagcatggac aggcaccaat tatccatcta atgccaaaaa tttacgcaat gattgcagaa
     6301 ggactattcg atcctacaca aatcattact cattcgctgc cactatcaga agcagcacaa
     6361 gcatatgaga tctttgacaa aaaagaagat aaaaatataa aagttgtttt gaaaccttga
     6421 attcagtaaa aaatacaggt gattttcttt atgcccaaaa tcaaacgaaa tacccatgag
     6481 atcgaaatag gaaaagaaga agatatcgaa atacgaggac gtcgcttccg cttctatttc
     6541 caaaatcgtt acacattgat ctcactggct gtcgatttat taaccgggat tttctatatt
     6601 tttggaagcc ttgcttcctt aactaaaatc cccgatcgat atggcaccta tttttatttg
     6661 gctggtgcta ttttcttgac gattcgtcct attctcagaa tcgtaaggaa catttttatt
     6721 tacgacgaaa aaaaagcaat gaagagaaca agcaaaaaaa aagaggcatg agaatttttc
     6781 aaatctcatg cctctttttt caccctatcg tatcactttg atacagacga gcggtcgtcc
     6841 cactttcttc cttgaccatt gtcaaaaatg tccactcgta tcgttcataa aacgtggtat
     6901 gatctgtaat taagtaaagt ttttcgtacc caagttgatg catttctttt ctgatttccg
     6961 ctaatatccg cttggctatc ccctgcttac gcttttccgg ttcaacaaac agggcacaaa
     7021 gatttggtgt cagatcaggg cggttatgga agtcgttttc aatgacgccc gctcctccga
     7081 cgatggtttc tttttcatct aagaccacat accattgagg aatactttcc ttattagcga
     7141 ttccagtacg aatactttcc tcatacacaa cagcaggaac tccccatttt gatgaaaacc
     7201 aattcgcgct ttgttttact aattctgggt gttctcttaa tttgatccag ttatatgtaa
     7261 ccaatgttta aacctccgac taaaataaaa cgtttacaaa aattatacaa gtctttatga
     7321 aaattagcaa tgacaacaat agtgatgtaa aaaaaaaaac ggaaaacaat cacttgttct
     7381 ccgttttttg attaatcaag catctaaagc ttcttttctt ctttcttgga tcgtagctac
     7441 cttgacgaac ggtagataga tcaaaataga aagaaccaaa ttgacagcgg ctagtacacc
     7501 acctgcaata ctttttgttg ccaatacacc gccaataatt ggtggagtta cccatggagg
     7561 cataacggta gctgctggca ctaaacctgt agaagtcgca aagtaagcaa cactaactaa
     7621 gaccattggt gtcaaaataa atggaatgaa catgatcggg ttcaacacga taggtaaccc
     7681 aaacatcgtt ggttcattaa tattgaagac acctggcgca atcgacaagt ttgttacaac
     7741 catatatggt ttgtttttac gtcctactaa ataaatagct aacagtaaac ctaaagttgc
     7801 acctgttcct cctaagttga caaagctgtc aaagaaaggt ttgttcacga taaacggtgc
     7861 gctatgtcca gctgcgattg cattaacgtt tgcttcaatg gctggcgcat tgattgtttg
     7921 catcaaagga tcgaccatat tcgctccgtg taaaccaaag aaccataaga atggtgtgat
     7981 aaatgcaagc agtaaggcag atggataaga gtttgcaagt cccataaatg gttcttggac
     8041 cactgtatag aaagaaccta cgatatcatc aacaccgaat gcagcaaaaa ttgcagcaac
     8101 taaagcaaac gcagagatag tgatcattgc tggtagtaat gaagcaaatg cttttgcaac
     8161 tgccggtggc acaccatcag gcattttgat gatcaatttt tcatttccgc ttaaacgtac
     8221 aaagatttct gttgaaataa tcccaacaat aatagcaata aacaaaccgt ttgagctcat
     8281 acctaatgct ccgcctaaag cgaagaaaga gcctaaagaa atcacacctg cggaaacacc
     8341 gtcttttcgg tagccgttag ctaaatgata agcaagcaag aaagcaatca agacagaaag
     8401 aatggcaaat gtaccgttcc aagcagcagc cccgaatcct ttccatgatt caccaccaaa
     8461 aattgagttc atcaattctt ggaacccggg aatcggtaag ttattgatca ttactgctaa
     8521 tgctcctaag atcattaacg gcatactcac cataaatgag tcccgaatcg caactaaatg
     8581 ccgttgtgca ccaatttttg atgctacagg tataaaatgt ttctccataa atgcaacaaa
     8641 tttatccata aatcttccct cttttcttta ctgtagatta cgcgttcaat cgacgataca
     8701 gattaatgat ctcttttgct aaatctgtaa aagctataga tgtcatcaga tgatcttgac
     8761 tgtggaccgt caaaagcgtg acttcaacgt gatttccttg tgcttcttgt gtcagcatct
     8821 ctgtttgaga gtgatgtgct tggactaaag attcctctgc atctttgatt ttttcatctg
     8881 ctaaagtgaa atcacctttt ttcgcagcag caatcgcttc cattgcatcg ctttttgcat
     8941 ttccgccaaa catgatcaga cccatgatgg cttctagatt tttttgatct tccatttatt
     9001 gtatcctccg ataattttta ttatttgttt attagttttt ctgcttggtc gagtactttt
     9061 tcaccattca tcatgccata gtcagccata ttgattacat ctaaaggaat gcctttaggt
     9121 gctagctttt cagcaaattg attttgcata aagcgtactt gcggtcctaa aagtaaaacg
     9181 tctacatttt tagattctag ttgattatcc gcatctgaag cagatacagc aaagatgtct
     9241 gcttccattc cttttgcttc tgctgccttt tgcatttttg tgactaggag acttgtactc
     9301 attccagctg aacatacaag catgattgtt ttcttttcca ttttaaacac gttcctttct
     9361 atacttacac ttgtatataa gcaagtagcg tgccaacttt aaaagcgctt taaaaagttg
     9421 atatcatcac atttaaggtc tataccaagt tgcatacaca ctaaaaaaga aagcgcacac
     9481 taaacacaca aattaatttt tattaccttt tttcttttaa cgtgcacaaa aaaagttgtg
     9541 acacaaaact tgtcacaact tttttcaaat aaacggtatt caaaagcttg catctgcggt
     9601 aataagtcca accaagttaa aaacataaga tgttgttttt actttgctat tcttattact
     9661 tgatgcagga cagctttttc acaacctctc aataaacggt gttcaatcag ctgaccctgg
     9721 gtattagctc aaaacgctgg attcacaacc tcttttattt caaataacca gtaaatacaa
     9781 tgaacatcta caaaaaactt ctatttattt atagatttcg tcaggcaaat ccaattctct
     9841 cttatcaatc aaagtctgat accacgaagc agattttttc aatgttctgc ttcgttcatc
     9901 gttcaattcg attcgaacta atccatatcg attcttaaat gcattcattg gtgacacaca
     9961 gtcagtgaat gcccataaca tatagccttc gcaatttgcg ccttcttctg ttgctttgat
    10021 caagtaatgc aaatgctgtc cgataaattc gatacggtaa tcatcttgca cgattccttt
    10081 ctcatccata tactgttctt catattctct tcccataccg ttttctgtta tcagccaagg
    10141 gatattatga taattttctt ttagatacat ggctatatca tacatgattt tcggatagat
    10201 ttcccatccc ctggaattat tcattttctt cccaggtaaa tcaaagactt cataatatcg
    10261 ttcaggatgg aaaggtgtct cttcattcca ttgataacga ggggcgcgaa cgcgtttagg
    10321 ataatattga ttgattccaa ggaaatctac tgtatgatgc tgaatcgttt ctaaatcctc
    10381 tgttgcagga tcgaaataaa tcgattgttt ttgacacaac tccaggaact cttctgtgta
    10441 gtatcctttt accatcggat caaaaaatac tcgattataa aacaaatcat acatataagc
    10501 agctttttgg tcttctggag aattggatcg agcatagacc atttcaggat ttaaaataca
    10561 gccaatcctt ccaccataat ttccgctgcg gtaaatctct actgctttag ccgttgctaa
    10621 aactttatga taattccaca tcatccactt ttttgtgttt tgttcatgcg gccagcgaac
    10681 agcatccaaa tagcaacgcg tttggggaac gattggttcg ttgaatgtaa accagttttt
    10741 taccctatca ccgtaacgat caaaggcaat ttgagcatac ttagcataaa aatcaactac
    10801 ttttcttgaa gaccagccat catatttttc caaaagaaaa gctgggactt cataatgttc
    10861 caaacaaatc atcggttcta cgtctgcttc gatcaaagag tcgatcattt cacttatatg
    10921 ctgagcatat tcttcatcta ctatacagtt ctcataatca gtaaaaaaac gagcccaatt
    10981 gatagaagtc cgataatgtg tcagatggat ggatttcatc agatccacat cctgctggta
    11041 ttgttccata aaattagttg ctacggctgg gccataccca ttatgccaaa caaaatgttc
    11101 atttttatac cagctatcta taaacgaatc ctgtccttct ttttttcctt tccaaccttc
    11161 cgtttgccaa gcagaagatg cagcaccaag aataaaattt tttggaatag taattttcat
    11221 gatttcctcc tgttttttag atcccatcat tttccacacg atttgctact tttacaaatg
    11281 gcagatagat caaaatagaa acaataatac aaacaagttg cgtaataact gcaccgatat
    11341 ttcctgctgt tgccagataa gcattgacga tcggcggcat tggccaaggg accattacaa
    11401 ctgctttcgc cgcaaatcct aaagcggttg caaaataacc aatcgttcca gtgataagag
    11461 gcgttaagat aaacggaata gctaaaattg gattcagcat gatcggcata ccaaaaataa
    11521 ctggttcatt gatgttgaag atcccaggag caagggataa cttggtgatt tgtttcatat
    11581 cttcccgttt tccaactaac aatactgcaa tcagtaaacc gatcgtgact ccagacccgc
    11641 ccatactcat atacatatcc caaaatggca tagtaataat gttcggtact tcttttccag
    11701 cttcaaaagc ttccgtattt acagcaattg ccgctaaaag caacggttcc cgtatcggct
    11761 tcaccatttg atttccatgg ataccaatca cccaaaagac ttgcgcaata aacatcaata
    11821 gcaaaatacc cggtaaccct tgtacgacac cttctaatgg gcgttgtacg acattgtaaa
    11881 tgatatcata aaggtacatt cctgtaagtt ctttgatgat aaatcccgca gccgcgatac
    11941 ccgatacagt cagaatcgtc gggaataaag cagaaaaact agcagaaaca ttcgttggca
    12001 cggtatcagg cattctcagc tgtagtttct tctgtttcct caaccagcaa taaagttcaa
    12061 tagaaaggat ggagaccaac attcccaaaa ataacccttt cgtatctgta tattgtttag
    12121 ccaatacgtt ttctactata acagtctgat tttcattcac taattcataa acagttggat
    12181 taacagataa ataagacatc actgcgatga taccagggaa tacaccatcc actttattca
    12241 gcttggctaa ttcgatccct atcagaaaaa cagcatagat ggtcaagaaa cttagtgtga
    12301 catagctgat ggcagatgcg ataggcttta attcttctaa aaaacgcaag aaacttatct
    12361 gtgctaagcc attttccgag tcaaagacca ttgctgaaaa caatgtgcca aaagcacccg
    12421 taataattac cggaatcaat gcagcaaatg cgttttttat caccatgata taccttaaat
    12481 tattgattct cgttgccacg ttccctaaaa cattggctaa tttatccata aaactcattc
    12541 cagatcccct cattcctgct tcttctcctt gacgtcatct ctttttgtct attagtcagc
    12601 gcttacattt cgatgaacag aaactattta ctcctctttt ttaccaaata taaaacaaaa
    12661 attcatctga tgtatttatc ataaaataca tcagatgaac tgtcaattag tttctttttc
    12721 tcctattatt ttctgtaatt ctctccgatt tattgccata tggacagtca ttgcatcaaa
    12781 cgcagcaagt gcattccgcc tttcgatggc ctgaacgatc tctgtatgaa tatcgatcgt
    12841 ctcgattttc agatgctgga tatcataatt tttattaaac aaagcaattg attcattaat
    12901 gattgggata atatgcagca aggctacgtt tccgctagct tctgcaatca tcgtatgaaa
    12961 atcgatgtct aattgaacat gttcttgtgt gccttctcga aaagaagttt caatcttttg
    13021 cgttaatttt ttcatttgga cgatttgatt cttcgttgca tattccgctg ccaaacctgc
    13081 catcttaggc tccaataaat atctcagttc aaataagtct cgtatcatcc gatcctgatc
    13141 ttcaatcaaa gaaaaaccga gtgggtcatt ggcaatccct cgcttatcac tgacaaatgt
    13201 ccccgctcct tgccgaactt caaggatatt cctggaagct agagcccgca cagcttctcg
    13261 caccgtgctt cgccccacct ctaaataatc ggacaattca tattcattcg gcagtttatc
    13321 tcctacttgc aactgcattt cctttaaata tctaaggatc ttgtcagtag ttacttctac
    13381 tagggtttta ttttcttcca aaccacatac ctccttttca tctgatgtat tttttcgtaa
    13441 ttattataac acgtttgaat catctgatga ttttttgtat acaaaattga ttaatccgtt
    13501 catagacata caaacgaaga agatatttac cataaaaaag actaggataa aattcactcc
    13561 tagccttcga tcatttttat tttgaacgac aaaaaatatg atgttcaata acagacgatc
    13621 ttcattcgat tcttgatgtc atcttttgtt ttttttaata tatggataaa aagtttgatt
    13681 acatcgtttc tattctagaa tttggtcgat tctcaattct tcttctggtg agaaatctaa
    13741 attatccatc attcgaacac tttcttgtaa ctgacttaac cgacttgctc cgaccagtac
    13801 acttgtaaca gatttttgtc gcaaattcca tgcaagggcc atttgcgcta atgattgtcc
    13861 tcgtgatacg gcgattgttt gcagtgcttt gattttttcc agagttgatc caacttgttc
    13921 ttctgaaagg aatggtattt ccttacgatg tgctctagaa tcttcaggaa taccatgtag
    13981 ataacgattt gtcagcaacc cttgagcaag cggactgaac gtgattgccc ctagcccttc
    14041 ttcttctaat actggagata gatcgtcttc tagtagtgca cgagaaaaca tattgtagcg
    14101 catctgatga ataatgaacg gtgcttcctt tctttttaaa atttcagtca ttttttttgt
    14161 atcttctcca ttatagttgg atataccaat atataatgct tttccttgtc ttacaagttg
    14221 catcaaagct tctgctgttt cttccaaagg tgtatcaggg tctgggcgat gatgatagaa
    14281 gatgtcaaca taatctagcc ccattctttg gagactttgg tcacaacttg aaatgatgga
    14341 tttacgagag ccccattccc catatggccc ttcccacata tgataacctg ctttgctaga
    14401 aataatcagt tcatcacggt aggcttgaaa atcttctcta aaaatacgcc caaagttttt
    14461 ctctgcagct ccagcagggc ctccataatt attcgcaagg tcgaaatggg taattcccat
    14521 gtcgaatgcg cctcttaaaa tctctctttg attatggata ggatcataat caccaaaatt
    14581 ttgccataat ccgagagata aaatcggtaa tttcaaacct gaatgaccgg atttacgata
    14641 ttccattttt tcataacgtg cactatctgc aatatacaat ttttctcctc ctcatcaaat
    14701 ctttttaaaa cgctttcttt tttctatttt tagtttacta cattttaaag aaaaggagtt
    14761 aatcaaaatg attttttcgt atattttttt gccatttgtt ttttactcgt tgatagatca
    14821 gaaattgatt acgtgcttgc tggatttttt tataacgttt cggttgtttt ttgtaaaatt
    14881 gctgatgata gttttctgct ggccaaaacg taccggctgg ttcgattttt gtgacgattg
    14941 gttggtggaa agttcctgaa ctgtctagtt tctgttttga ttgttccgct aattcttttt
    15001 gtcgttcgac ttgataaaaa atcactggac gatattgctt ccctctatct tgaaattgtc
    15061 caaatgtatc tgtgggatca gtaatttgcc aatagattgt cagcaactcg ctataactta
    15121 tttctcttgt gtcataaatg atctccacag cttccacatg acctgtgtaa ccaccactta
    15181 cttgatcata atttggtttt tcaacatgtc cgcccgtgta tcctgacaaa acagatagga
    15241 tccctttttt cgattcaaac ggctcgacca tacaccagaa acatccccct gcaaatactg
    15301 cacgttcttg atagtcagca tcttgcatgg catgcttgga aaagtcatat ttttgctcct
    15361 tatcaaatcc ttccgtaatc aataaataaa agtccattac atcaggcgtc agattcattc
    15421 ggatagctaa tggacgtagt gttgcttcta gttttgataa ctgttcttta acggatatat
    15481 tttctcttat gtcattcttt gtctgaatca atacttttcg ttcccaatct cgtgtattcg
    15541 gattcaaaat cagattataa agtgtttgaa tgaatatttg ttcctcatcc atagattctc
    15601 ctcctttccg aagaagacaa gctagtgact ttagctgtaa tttatcataa agtgaggaaa
    15661 taagcgatta cttcatcccc ctacagattt ttcgtataaa aaagagagaa tcctta
//
LOCUS       DACGDM010000056        14983 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.057, whole genome shotgun sequence.
ACCESSION   DACGDM010000056 DACGDM010000000
VERSION     DACGDM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.057"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            31..540
                     /locus_tag="IXR05_001878"
     CDS             31..540
                     /locus_tag="IXR05_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4260370.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            633..1795
                     /locus_tag="IXR05_001879"
     CDS             join(633..909,909..1795)
                     /locus_tag="IXR05_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4260371.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2075..3055
                     /locus_tag="IXR05_001880"
     CDS             2075..3055
                     /locus_tag="IXR05_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4260372.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3177..4595
                     /locus_tag="IXR05_001881"
     CDS             3177..4595
                     /locus_tag="IXR05_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAQ4260373.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4666..6135
                     /locus_tag="IXR05_001882"
     CDS             4666..6135
                     /locus_tag="IXR05_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4260374.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6145..6612
                     /locus_tag="IXR05_001883"
     CDS             6145..6612
                     /locus_tag="IXR05_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAQ4260375.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6648..7520
                     /locus_tag="IXR05_001884"
     CDS             6648..7520
                     /locus_tag="IXR05_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4260376.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7601..10135
                     /locus_tag="IXR05_001885"
     CDS             7601..10135
                     /locus_tag="IXR05_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4260377.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10291..11064
                     /locus_tag="IXR05_001886"
     CDS             10291..11064
                     /locus_tag="IXR05_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260378.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11057..11848
                     /locus_tag="IXR05_001887"
     CDS             11057..11848
                     /locus_tag="IXR05_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4260379.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            11858..12349
                     /locus_tag="IXR05_001888"
     CDS             11858..12349
                     /locus_tag="IXR05_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4260380.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12367..12777
                     /locus_tag="IXR05_001889"
     CDS             12367..12777
                     /locus_tag="IXR05_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4260381.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            12781..14181
                     /locus_tag="IXR05_001890"
     CDS             12781..14181
                     /locus_tag="IXR05_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAQ4260382.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14204..14578
                     /locus_tag="IXR05_001891"
     CDS             14204..14578
                     /locus_tag="IXR05_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4260383.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5204 a         2104 c         3014 g         4661 t
ORIGIN      
        1 ttgtgtttta ttgtttaggg ctatactata ttggtacaag gaatagaaag aggtgtttat
       61 gtggttgata aaattcagtt taatcaagtt atagaagaat tcatcaaagt aaataattta
      121 atgacccata ttcaaaaacg accaatcaga ataactaatg atctaaaact cagtacgagt
      181 atgattcatt tgattgatgt gattggaaat tatcctgaaa ctagtattac ggaattagct
      241 gatcgattag gcgttaccaa aggagctgta tcccaacaga ttcccacttt agagaaaatg
      301 aatcttataa gcatttctca aaaaaaagga aataagaaaa ctaaacttgt atcgttaaca
      361 aaatatggtc gaaaggtgta cgaatcacat aattatttac atgaagagct ttatagctca
      421 ataaatgaag cgttagaatc attctcacca gaccaaattt caaccattaa acagattcta
      481 gaaaaagtat cttatacaat caatgaatat caagtaagtc tgacaagaaa ggaagattga
      541 catgaaaaaa atgatttttg aatcggctac actagactag acagaaaaaa taaggtgtgt
      601 aaaataaatg aaaacacact ggaggaattt ttatgtcaag acgtcaacgt agaacctatt
      661 caaaagaatt caaacaacaa gtcgtcgatc tttatctcgc aggaaagccc cgagctgaaa
      721 tcattcgaga ttatgagctg actacctcgg cctttgataa gtgggtcaag caagcgcaaa
      781 ctactggctc gtttcaggaa aaagataact tgatccctga acaagtagaa ctaattgcat
      841 tacgaaagaa aaataaacag cttgaaatgg agaatgacat tttaaagcaa gcggcgctga
      901 tattgggacg aaaagacaag taattgatac caataagcac aaatactcaa tatcagcgat
      961 gtgtaaagtg ttaaacatct cttgccaaac ctattattat caagccaaac cagttgaaga
     1021 tgaatcagaa ctggaagaac tcgttcaaga agaatttatt cgcaatcgaa aagcttatgg
     1081 taccaggaag ctgaagcagt gcttggccaa tctaggtctt caagtgagtc aacgcagaat
     1141 cggccgtatg atgaaacagc gtggcttgcg ttcaacatac acattggctc atttcaaatt
     1201 ccattcttct acttgtaacg aagccaagac cgccaatatt ctagacggaa ccttcctaca
     1261 ggaaaagtca ttagaagcga ttgtaaccga ccttacctat gttcgtgttg ggaagaaatg
     1321 gcagtatatc tgcctgattc ttgatttgtt taatcgagaa atcatcggct attcatgcgg
     1381 ggagaagaaa gatgcgacgt tagtcaagga agcttttgca aagattccgt actcgttgaa
     1441 taatgtacaa ctttttcaca cggatcgtgg aaaagaattc gataaccaga cgattgacga
     1501 aattttatgg gcctttaata tcacgcgttc cttaagcaaa aaaggctgcc cctatgataa
     1561 cgccgttgca gaatccacct ataaatctgt caaagtagaa ttcgttcatc aataccgctt
     1621 tgagacattg gctaatttgc gattagagct atttgattac gtccattggt ggaataccat
     1681 ccggctgcac ggcacgttag gctatgagac accgatcagt tttcgacagc agagattggc
     1741 gcagcgaatc cttgataatg agctcggatg tgataccggt ggcgaggcac cttaattatt
     1801 tgaatgagct tctgccttag agaatcagat tcgaggaggc tcgttgtcaa gggcagtcgg
     1861 aacaccagca gcaagcttac gcaatacctt ataatttttg tcaaaaaaag tgttgccatt
     1921 ccacatatat ctttaaacag ctattgccag ataaaaataa atgatattat atatataaat
     1981 acttatccga aaaggggaat gagagagtca aggttcttgg aatgtcgaat agtcgagtag
     2041 gtagattttc tatctacaac cttgttgttt aaaaatgaaa aaaattggaa ttagagaagt
     2101 tgcgaaagag gcaaatgttt ctcctacgac tgtgtcgagg gtattgaatg atcgtggata
     2161 tttgagtgag gaaacaaaaa gaaaagtttt tgatgccatg aaaaaattag aatactatcc
     2221 taatgaactg gcgagagcac tttttaaaaa cgaaacatat accgtaggtt tgatttttcc
     2281 tacaattact aatccatttc acgctgagtt aattcaagat atcgagttcg agctttccag
     2341 caggggatat aaagtgttgc tgtgcaatag cttaaacaat ccaacaaaag aaaaagagta
     2401 cttgacgatg ttgagaaaga atcaggttga tggaattata gtaggaacgc acaataaaga
     2461 tattgcggat tatgatattc cagggctacc tattgtagcg attgatagaa gtcttggtga
     2521 aaatacagtt acagtatctt gtgataatta caggggtggg gaattagcta ctcaactact
     2581 tgtaaatcat ggctgtcaga atatactgtg tattcgggga gatagtaaga taaagctacc
     2641 cgcgaatagt aggactttag catataaaga tgttttgaat aaattcatgc tggaaccgtt
     2701 agtcctagaa gtaccatttg taaaagaaat caatgaaaaa aatgaaataa ttaagacata
     2761 tctggaaact catccaaata ttgacggggt ttttgcagga gatgatttat tggcttcttt
     2821 ggcgattaac aacttaggaa gttcgggcaa aagagttcca aaagaggtta aagtgattgg
     2881 atttgatgga gctcaacaaa cattgattta taatccagaa ttatcaacta ttcaacagcc
     2941 tatagatcaa atatctaaag tagcagtaaa aaaattattg aatatgatta agggcgaaaa
     3001 ggagacggat gaactttcac ttccagtaaa gctcataaaa aaaaatacag cataagttaa
     3061 atcggcgaaa aattccttcg tcgatttaaa aatattttta tgaaacgggt tgacatatga
     3121 aacgggttga catatattag ttgtgaagat aaaaaccttt tcactggagg aagaaaatgg
     3181 agaaattatt aattaaaagc aataatcatc aactttacta ccaacctaag gatgtttggg
     3241 tcggagatgt tatgccttac gggaaagaag gaaaattctt tatttatcat caacgtgata
     3301 ctagaaatcc agttcctttt ggagaaccgt ttggctgggc tttagcaact acgaaagatt
     3361 ttgttcattt tgaagacttt ggggaatctc ttttaagagg ggatgacaat gagagagacc
     3421 agtttatcta cgctggttct gtatttgagg caaatggaaa ggttcacgca ttttatacag
     3481 ggtataatcg tgaattctta gcgcagggaa agacatctca agtgttgctt catgctgaga
     3541 gtgatgattt tgttcattgg gaaaaatcag aaacagcatt ggagttagaa ccacaagaag
     3601 ggtatgatat tcgaaactgg agagatccat ttgtcgtttg ggatgatgaa aaagaagaat
     3661 atttgctaat tttaggggcg cgaaagggtc aggataaaca tctacaaacc ggacgtttag
     3721 tggaatttac atcaaaagat ttaactaatt gggaattcaa aggtgatttt tgggctccgg
     3781 gattgtatac catgtttgaa atgccagaac ttttcaagat tggtgactgg tggtatcttg
     3841 tctattcaga atactcagat ggaaataaaa tactctatcg aatgagtcaa agtttggaag
     3901 gtccttggat taagcctaaa gatgaagctt ttgatggacg ggcttattat gcaggtagaa
     3961 cagcttatga tggaaaacgt cgagtcctat ttggatgggt accaacaaaa gatcaagaaa
     4021 atgataaaaa caattattta tggggaggta ctttggttcc tcatgaagtc tatcaaaaag
     4081 aggatttttc acttggggta aaacccatag acgaagtgtg gaatgcattc ataaatttac
     4141 atgatattgc cgatgtagag atagaaacag cagacacaag agaagaagta acgcttgtca
     4201 aaaatagtgg aactttgttt aatttagaaa caacaatttc atttgatgag aatcttagtg
     4261 acttttcact gagattatat aaaaaccttg agacagatga atcttacgaa tatcgcttca
     4321 atttagatga ggggcgtctt acatttgata aaaacccttg ttacccttgg tttcaatata
     4381 tggataaagg acttattaga cctatatctt taaagcctaa ccaatcttat aaactaaaag
     4441 tgattgttga tgacaatata atgacacttt atattgatgg aatcgctctt aacgctcgtg
     4501 tacatggttg ttttggtcaa gcaattacta ttacagcaac aaatggatca atgactgcaa
     4561 taaataccaa gttttcaaat gaaataaaga aataataaac gtcaatcatg tggcaggtct
     4621 gaaaatcaaa catgacctgt cacatttaaa agggaggata aatgaatgga ctacaaaaaa
     4681 attgccgaag atgtattgga aaacgttgga ggaaaagaga atatctcaag cgctacacac
     4741 tgcattactc gtttacgttt aattcttaaa gacaaaagca aagcgaatat ggaaatgctt
     4801 gaggaaatag aaggtgcaaa aggtgttctt ttcaatagtg gacagttaca agtaattttc
     4861 ggaacaggta taattgaaaa ggtttacaaa gagttcgttg aattgacagg agctaaggaa
     4921 gtatccgttt ctgaaatgaa agacgaagga gtcaataatt caggaaatag acttcaacga
     4981 gcttttaaag ttttctcgga tatctttatt ccgatcattc cagcttttat tggggcagca
     5041 atggttttag gaattcgttc gttgattacc actcctggaa tgtttggaat ggatggctca
     5101 ttcgctgatc acaatgtatt cctaaatgat ttatccaaat ttctgggtat tattgcaacc
     5161 acatttgatt atttaccagt tttagttatg tattctgcaa caaaacgttt tggcggaaac
     5221 cctattttag gattacttgt aggatttgtt atgattcatc caggactagc caatcggaat
     5281 gatttcgtca tgggaactat aaagcctgat tattggcatt tatttggatt aagcattcca
     5341 gcagttgcgt ttcaaggggg tgtttttcca gcaattttga cttcttggtt tttagcaaaa
     5401 gttgagaaaa ttacaaataa atattctcct caagtacttg cttacatttt agtcccaact
     5461 gtgacaattg ttcttgccaa ctttgcacta tttttagtgt ttggtccatt ggggaatttt
     5521 atcggtaatg ttttaggtgg aatcattgat ttcctatata tgaagatggg tgcctttggt
     5581 gcttttgttt ttgcaggcgc gttacaacca ttagttgtaa caggaacaca acatgctatt
     5641 caaggtattg aggcaaactt agtcgcaaca actggattca attatatcca acctatttgg
     5701 tcagtttcaa ttattgccca aggtggcggt tgtattggta tgtatttact ctttaagaaa
     5761 aaatctaaag atagagatat tgcgatttca agctttattc caacactggt aggtattact
     5821 gaaccggcta tctttgctgt taatttgaaa tattcaatcg ttccttttgt ttgctcgttt
     5881 attggtgctg gttttggtgg agcatttatg aaaatttttg atgtaaaagc cattggacaa
     5941 ggattgactg tattgccagg tctgactatt gctaatccag ttcttcctta tatatttggt
     6001 aatctcatag cattcatttt accaatcatt tttattctcg cttatgataa atataaagtg
     6061 tttatccctg aagctaaaca ccgtaaattt gcagaaaaaa ctgactcaaa aaaattgcca
     6121 gttcaagtaa agtgagatga gagcatgtta aattttttta gaaaaaatga aataagcgtt
     6181 gtagcacctg caaccggtgt ttttgaaaaa ctggagaaat taagtgatcc agtcttttca
     6241 aaaggaatga tgggacaagg atttgcaatt gatgcaaaaa acgaaacgat tgtatctcca
     6301 atcgatggtt ttgtttcaag tatttttcct acaaaacatg ccttaggaat aaaaacaaaa
     6361 tcaggaattg agatacttgt tcatgtagga atagatacag ttgagctaaa tggtgaggga
     6421 tttgatatta aagttcaaga aggacaaaaa gttaaggctg gggatattct tatgaccatt
     6481 aattttgtag tttttgaaaa gaatcacaag actaaagatg tcattgttgt ttttccagac
     6541 taccaagacg aaattttcat tccgaaactt gaagaagtaa aacaaggaca agaattgttt
     6601 gttcttggct aatgataagt aattaataat agaatcgagg aaaatgtatg gtttttgggg
     6661 ctattgaagc tggtggaaca aaatttgttt gtgccattgg agataaagat ttgaacatat
     6721 ttgaaaaagt cagctttccc acgactacac ccaaagaaac aatgaattta gttttagatt
     6781 tttttaatca tcataaagat gatttagaag gtatcggagt gggatcgttc ggtcctattg
     6841 atattcattg tgaatctaaa acgtatggct tcattacatc aacgccaaaa cttgcttggc
     6901 aggattttga ttttattgga agtttaaaaa agcaacttaa tattccaact gcttggacga
     6961 ctgatgtaaa tgcctcttgc tatggtgaat atgtttctgg aaatggcaga ggcctttcaa
     7021 gtgttgttta ctataccgta ggaacgggca taggaggtgg cgctatccaa aacggaaact
     7081 tcattgaagg ttttagtcat ccagaaatgg gacatatgct tgtaaaacga cacaataaag
     7141 acaacttttc tgggacatgt ccattccacg gagactgttt agagggctta gctgctggtc
     7201 cggcaatcga aagaagatca gggaaaaagg gacaagaagt gactgaaaat gacgttactt
     7261 gggaaataga agcttattac attgctcagt gtgcatataa tacaacattg atgttatcac
     7321 ctgatgtcat tatatttggt ggcggagtaa tgaaacaaaa acacttaaaa aagaaagtac
     7381 aagataagtt tattgagttg atcaacggat atgtcgctat tcccgatgtt gacaattata
     7441 ttatgacacc aaaattgtta gataattctg gtattgtagg ttgtttagct ttagcaagag
     7501 acgttaaaga aaaatcttaa tttggaaaaa agatcgtctc gactatttgt ttggttgatg
     7561 cgatcttttt ttcaattagt aattgaaggg acgcctaaaa gtgaaaaaaa aaatgaaaga
     7621 tgaagtatta gagtatatca aaaataattt aaagtattac gatttttctg ctcaagatat
     7681 tgcaatgaaa ttttgtatta aaagaaatgt cgcttcccac tatttgaatc agttattttc
     7741 agatggaaaa ttactaaaga atgattctgt tagaccagta atgttcaagt ataatcaaca
     7801 aaagccaaaa gactgctttt ctaagtttat tggagcagac atatctttga aatccactat
     7861 agataaatgc aaagctactg taatgtatcc ccctaatggc ctcccattaa taataaaagg
     7921 aaacagtggc gttggaaaaa gttttttagc aagtttgatc tatcagtatg ctcttgatag
     7981 aaaagtaatt cataatgacg caaaatttgt tgttgtgaat tgtgcagatt atgcaaataa
     8041 tccagagcta ttgtcagcag ttttatttgg atataaaaaa ggagccttta ctggggctga
     8101 aaaagatact gcagggatgc tatcttctgc taatggagga tacctttttt tagatgaggt
     8161 tcacaatcta agtgcagaaa accaagagaa attgtttctt cttatggatt ctcaaaagta
     8221 tcgtaaactt ggtgaaagtg tgcaatggga gtatgcaaat gttcgcctta tcttagccac
     8281 aacagaagat aaaaatacct ctttgttagc aacttttaga agacgcatcc cagctgaaat
     8341 cactctgcca gattacaata atagaagtac atctgaaaaa attcaattat tatttgaatt
     8401 tcttaaagat gaagcaatta cgattgattc aaaaatattt tgttcgattg aactttttac
     8461 tgatctttta tcgaaaacat ttgaaggaaa tgttggagaa ttgaggaatg aaatcaagct
     8521 tctttgtgca gaaggttatt taggaaataa gagaaagtct tcaatttatt taggggacaa
     8581 actagacagc ggtttttgga tagatccaga aattagtata gatttaaaaa aaatgtttct
     8641 taaatcactt tctgaaattg atttgattga actttttcaa aatcacattt caattgaaga
     8701 aagcatgagt caattaagag atagaatact taaagagtgt gcaggttctt ctgagtataa
     8761 ttatttagaa agtgacgaat ttatagcatt aagaaactat gttgttaata aaatatcacc
     8821 aattattgat tcgacaggtc tatgtttatt agatgaattc ttggcggata tcagtctatt
     8881 tataatgttt attgatgtaa ttgaagaaac atcaagaaat tttttgctgt ctaagttcag
     8941 aaaatttcgt atgaaaaatg ataaacaaaa attattggca aatgagattt ggagtagttt
     9001 agaagtcgaa gaaagtaaac aagaactttt gttgaaatgg atactttttc ttgtaaagaa
     9061 gttctatgtg aaaataccag aaacccattg tctgatagtt atgcacggta aaataacagc
     9121 ttctgcgatc gcaagggaaa caaataagtt gctgaataca tatgtttatg aggctttcga
     9181 tatgccaatt gaaggtgaga ctagtgactt aattaaccta atcaacaatt tttgtaaaag
     9241 tatagatacg acgaatggac tcattctgct agttgatatg ggatcattgg aacaaatgta
     9301 tgaaaaaatt gaatccaatg taataggtga tttggtaatt ttaaacaatg tttctacagc
     9361 tttagcgatt gaatgtggga ttcaagtttg ccaaaaaaag ccaattagtc atttttacca
     9421 gatggatttt gattcgtttc aagttaaagt tcagtattat aaaggattat cacaaaagaa
     9481 aaatgtaata gtatcttgtc tctctggtga ggggatttct gaaaaagtta aggatatttt
     9541 aaaacggtat ctcgataatc aagtggagat tttgattttt gattttaacg cattaaagaa
     9601 aatagcaaag gaaaaagata ctatgatttt taagaataca atttgtgttc tttcaaccac
     9661 tgaattttac attcaaggaa tcgattgttt aaatttagaa aatctaatta atgggaatca
     9721 aaccttagaa aaattaaata agtatatgga ctcggatagc tgtgagttct gcttaaatga
     9781 attagttaaa ctctttacta ttgaaggcgc tagtactaag cttcgctttt tagattccaa
     9841 aaaagtattc aatgagatag aaaaagtact atatttgtat gaaaaatatt acgatgtcaa
     9901 aatcccaagt tttctgagaa ttaatctatt tctacatctt tctggaatga ttgaacgaat
     9961 tatgattggt gatggaataa caaatgaaca tttgaaagag ggagcgcaac tatttgatac
    10021 ttttttaaat gtatcaaaag attttttttc agaaatcaaa gatatttact gtattgaaat
    10081 acccaaagga gagtatgagt taatctatac aatttttgag cagactattt tctaaatagc
    10141 atactagcgt ctaaaaaaat gaaagggtgt ccaaagtata tttagacgct catttaatta
    10201 atatttactg tattttcccg ctttattgga taatgttagt tggcacagta attgcttata
    10261 taaaagtata agaagaaagg agagaacaaa atggcgtttt ggcaaacatt tttagttgtg
    10321 ttgtatggat ttttcattaa ctgggataag gaagggccca aaatcggaac ctcccaacct
    10381 gtcgttgcag gtttcttgac cggacttatt atgggagata ttcaaactgg actttatatc
    10441 ggtgggactt tgcaattaat gacactaggt attactagtt ttggtggtgc atcagtaccg
    10501 gattatcaaa cagcagcatt gatcggtact tatttagcaa tctcaactaa ccaggatgct
    10561 tctataggaa taactttagc aataccggta gcaatgttaa ttgtacaact agatgttcta
    10621 aagtggtcaa caaacatttt ttttcaacaa aaggcagaaa aattcgcaca aaaagaagat
    10681 tatcaaaaat tagagtggat gcaatatttg gcatcaatta atacaagctt tgtatctgga
    10741 attcctgttt tgttaactgt gatattaggc ccaacgttag tgggaagtgc aatcaattat
    10801 attcctgaat gggttaccgg tggtttaaag gtagcagggg gactattacc tgctgttggg
    10861 ataggaatgc tacttaaata tttacctaca aaagattact ttgcctattt gttagttggt
    10921 ttcgttttgg cagtttattt ccaaatacca attttaggga tttcgttact tggcgctgca
    10981 atcgcactaa tcgtatataa aaatagatca aataatactc aagtagcacc agctgcaaca
    11041 ggaggttttg acgaagatga ataagaaact gacaaaaatc gacaaacaag taattttccg
    11101 gtggattctc aatggtgcaa cttcattaaa ttatgaaaaa atggaagggt tgggttatgc
    11161 gtattctatg cttcctttta tcaaggacac atataaagat gatcctgaag gaatgaaaca
    11221 atccgtttta gctcacttac aattttttaa cactacgccg tatacagcgc cttacattat
    11281 tggtatgaat gttggaattg aaaaagaaga aaaaaataag tctttggaag cagtaagtgc
    11341 tctgaaaaca ggtctaatgg gtcctttagc gggaattgga gatagtgtat ttgtagttat
    11401 tccatggact atttttggag caattgcagc taatatggca ttggaaggta gttttgttgg
    11461 aattattttg tggatactgg catcaatttt attaaggatt actgcttatc ctttatacct
    11521 tgctgggaaa gaatcgggtg cgagcctact aactcaaatt gaaacaaaat taaagtctat
    11581 tactgatgca gtatcaattt tagggttaat ggtggtcggt gcactcattg ccacagttgt
    11641 aaaagtgaat gttggctttg aatttaaaca aggcgactta acaatgaccg gaaatgaaat
    11701 ctttgatcaa gttatgcctg gtttattacc tgcatgtgta gtagcaattg tgtattattt
    11761 gttaggacga aaggttaaac cagtttatgt aattctatta atcttagtag tttctattgc
    11821 gttaagagcg ttaaatattt tgaagtaggt gttgaatatg gatgaaaaaa tgaaaggtat
    11881 tatacatgtt cgtattgatg atcgaatgat tcatggacaa gtagcaacac aatggacaaa
    11941 tcaattgagt gctaacagaa ttatggttat taataatgaa gtagccaatg atgacgtaaa
    12001 aaaagctgta gttcgcctcg ctgcaccacc taatgttaga acttcaataa ttacaaggga
    12061 agtagcagtt aaaaatattc tttctggtaa atatgaagga caaaaagttc ttattgttgc
    12121 agtttctcca atcgatgtta aatttttgat tgataacggt ttaccaataa caagtgtaaa
    12181 cgtaggaaat ttatcaagaa ggaatggaac agaacgcatc cgtccgacga taaatattac
    12241 tgaagaagag agagaggctt ttaaagaact aattagtgat ggagttgaag tgacagtgat
    12301 acaaactcct agagattcaa aagaattttt aaaggatttt atttattaag aacagaggat
    12361 gagtggatgg agtttataat tacatctcat ggaaatattg ccattggatt tgtagataca
    12421 ttaaaaatgt tttttggcga taatttaaat tgtcatgtgg taacacttgg agatgcaggc
    12481 attgaagaat tccgtgaaaa cattgaaaaa atagtttctc aagtaaaaaa tcaagaagtt
    12541 atggtatttg ctgacttgat tggtggaaca cctttcaacg aatttgctaa aagaagtgaa
    12601 gtatttcaaa atgggtttca acttcttggt ggcatgaatt taggaatttt gattgaggct
    12661 gtcaatttga gattacaagg aaaaaaaagc gatgatatca tcgaaaatct aagaaatatg
    12721 aatacaattg cgtgtcttgc agatatgcaa agacatacta acgaagagga tgagtgataa
    12781 atgcaaaaaa ttttttacaa gcctaaagat ttttggtttg gggattgcat gcctttttat
    12841 aaagatggaa ctttttatct atttcatcaa cgagatacga gaaatcctaa acctttaact
    12901 gatccttttg ggtggtcact agttacaacc actgattttg tgaaatttga agaatacggg
    12961 gaagtaattc atcgtggtgg caacgatgac attgatcaat acatttacgc tggaagtatt
    13021 gtccaaggaa tcaatgagta tttagctttg tatactggac ataatcgcaa agctaagttg
    13081 gatggaaaaa cttcagaagt gttaatgatt gcaagttcta aagatttaat tcattggaaa
    13141 aaggatggcg aagcagcaaa acttgttcct caagaaggat atgataagaa tgattggcgc
    13201 gatccttttg caatttttga tcaagatcat ggaaaatacg ttttgatact aggagctaga
    13261 aaaccagcaa gtaagaaaaa gccgacgggg agattggtct attttgaatc cgaagattta
    13321 aaagattgga atttcaaagg agactactgg gctaataatg aatttaacat gattgaaatg
    13381 cctgatatat ttgaaattga tggaacgtgg tatttacttt tttcagagta ttgtgaagat
    13441 aaaaagacta aatatcgagt cggagcagga ttattttcag attggaaatc accagtagac
    13501 gaagctttcg acggaaaagc ctattatgca gcaagaacag tcggaactaa tgaaactggc
    13561 cgttttctaa ctggctgggt ggcaacaaaa gaaggggaga acgatcaaaa taactgggat
    13621 tggggcggtg cacttgttcc acatcaaatt attcaaaaga cagacaaaac tcttggtgtt
    13681 aaactgcctg aaaaaataat tgagaatttt aaagaaatca ctccattttc aagttttaag
    13741 ttagagaaag aatttggaaa aaaagaaaga gtaattgttc ctaaaatcga agattatttt
    13801 ctatttgaaa caactttgac tattacatcg ttaacaaagg agtttgcttt aaaattattt
    13861 gtagatagtg atactcaaga aggatacgaa tttcgtattt cattgattaa taatcagctt
    13921 actttcggaa aaactccgaa ctatccttgg cctcaaatgt ttgataaggg gctgcaacga
    13981 ccactatttt tggaaatagg caaagaatat gaactaaagt taattgttga tgatacgata
    14041 gctgttttat atattgataa tgttgcttta agtactagaa tgtatgataa agtcggaaca
    14101 gcattaagta tgactgttac ggagggagca atcaaggtag ataaactaga ctattcaata
    14161 aattatgaat gtggatttta aaacaattga agggatgatg taagtgaaat taaatggttt
    14221 acaacatatt ggaattccaa caaaagattt tggagcttca aaaatctttt atgaatcctt
    14281 agggtttagt ctgattaatg aagaaatgaa tgtgggaagt aaagtcggct ttttcgagtt
    14341 gaatggaacg ataatagaaa tatgggaaga taaaactact gagtgtagag gagccattga
    14401 tcatctagca ttagatacgg atgacataga tgaggtattc aattcaattc aagatttagg
    14461 atatgaatta ttagataaaa atattatgga attaccgttc tgggaaaatg gaatccgtta
    14521 ctttaatttc tacggaccaa atcatgagat tatagagata agccaaatga agaaataaat
    14581 agataacgaa gtgctctaag ttggtatgaa cgaaaagtac ttcatttttt ggtatcagca
    14641 tttcaatagt ttaatgagaa tttactattt caaattaatt caaagtgaca gtatttttta
    14701 cttatttggt ttcaaatttt gtaatccttc ctatttattg gaatacactc cacattttgt
    14761 atacaagtca tatcatgttt tagcaaagct cttaccaagc aaagttataa tgatgttttc
    14821 caaagtttga tctttcgatg gaggctaaca catatttttt gcaggacagc caaaattaga
    14881 tgtatagaat agagtctgtg aggcgtatag acagtttatt gtctgtatgc ctttttttat
    14941 tttgaaaaat ttttagtatt tttcgaaaaa tgctcactcc tag
//
LOCUS       DACGDM010000057        14878 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.058, whole genome shotgun sequence.
ACCESSION   DACGDM010000057 DACGDM010000000
VERSION     DACGDM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.058"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(359..1087)
                     /locus_tag="IXR05_001892"
     CDS             complement(359..1087)
                     /locus_tag="IXR05_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260384.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1065..2639)
                     /locus_tag="IXR05_001893"
     CDS             complement(1065..2639)
                     /locus_tag="IXR05_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4260385.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2868..3806
                     /locus_tag="IXR05_001894"
     CDS             2868..3806
                     /locus_tag="IXR05_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4260386.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3818..4729
                     /locus_tag="IXR05_001895"
     CDS             3818..4729
                     /locus_tag="IXR05_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4260387.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4753..6225
                     /locus_tag="IXR05_001896"
     CDS             4753..6225
                     /locus_tag="IXR05_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4260388.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6276..6887
                     /locus_tag="IXR05_001897"
     CDS             6276..6887
                     /locus_tag="IXR05_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4260389.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6917..8830
                     /locus_tag="IXR05_001898"
     CDS             6917..8830
                     /locus_tag="IXR05_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAQ4260390.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8958..11939
                     /locus_tag="IXR05_001899"
     CDS             8958..11939
                     /locus_tag="IXR05_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAQ4260391.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11936..13597
                     /locus_tag="IXR05_001900"
     CDS             11936..13597
                     /locus_tag="IXR05_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HAQ4260392.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13637..14569
                     /locus_tag="IXR05_001901"
     CDS             13637..14569
                     /locus_tag="IXR05_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAQ4260393.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4833 a         2348 c         2989 g         4708 t
ORIGIN      
        1 gccgcatatc ggactaagtt ttattcaaat ttgtcttcac caacacgatt tgacgaagag
       61 cctatttaaa taactacatc catttattct atcttctaaa atagcctttt tcatttcagt
      121 taaatagttc agcgccattt ttgcactcga cttgcatagt agttttttcc atattcctca
      181 acctcagcgg gggttgaaga cataaggaaa atcctatgcg ttatgctcaa ctggatctga
      241 ttaaatattc taatgtattt ttctctacca tcattaaatg gttaatagcc aaaaatcacc
      301 acttttcaat ggctccttgt tgtataagta taactagaag atgaacacgt ctgagaaatt
      361 atagaagctt tttacggtaa ttactggggc tgtgtccagt agtttttttg aagagaacag
      421 aaaaatagct cacgtgatct attcctactt tttgactaat ttcatcaata gataagaatg
      481 tgtctttcag tagagcactt gctcttttga ttcgaaagtc tagcaagtaa tcatgaaagg
      541 aataacctgt ttcttttttg aaggcccgtc ctaaataagc gggatggtaa tggaattgtg
      601 tagctacatc tttgagcgta agcttttcac tataattgtt ttgaacgtaa tcaatcactt
      661 gttgaattga ctcattaaaa gaatcatcag ttagagagtt ttgattagct gctgatttac
      721 gcattttttc ttcttgtact aacttaacta aataaggaaa atcaatgggt ttcgttatgt
      781 aacttttaat agataaatca atcccctttt ttgcatactg aaaattttgg tgggcactaa
      841 tgacaatact agtaaagtag cgattggatg tttgttgcaa agattcgatt aattcgagtc
      901 cagaaatttt ccccatcgta atatctgtga taagtaaatc aaagcgctgg ttttgcaggt
      961 ttttaaatgc ttcgtctccg tctgtgtagc agtgatcgat aatgatgtcg gggactttct
     1021 tcaaaagata atgccttatg ccttctacaa ttgtacaatc atcgtcaaca attgcaattc
     1081 tcaacatgca tattcccccc tttttgtatt ttgatagtaa tcgttgttcc gacgtgtagt
     1141 tggctttcta taacaaaacg tgtatctcca ggatagagat gctttatacg tcgaaaagaa
     1201 tttgagatgc cgatattctc actataagga atatcatcat taagtttttg ttgaatatgc
     1261 tccagcttgt cttggtccat tcctttccca ttttcaacga tttttaacac ataatggttg
     1321 gttgtttcag ttgcatagac agtcaaacga ttttcctttt ttgatgaatc gaagccgtgt
     1381 ttaatataat tttcaacaaa tggctgtaaa gaaagttttg gtaacattaa ttgatcaata
     1441 tgatcaatca gctgatagtc aaagttatgt cgataacgac gttgatgtag ttgcaaggag
     1501 aggtcgatat taattaattc ctctttcaaa tcaattatgt cgggctgata tgtattattg
     1561 cgatacaact tgctcaataa atatatactg tcgctgattt cttcgtcatc attcaatatg
     1621 gcagtcattc gaataaattc caaattatta aatagaaaat gaggctcgat ttgatattga
     1681 agtgctgcat actttgcttc ttgcttcaac caattatttt cataaagtgt tttttgatat
     1741 gtagcattat ctaaataaaa ctgattgata tgcatagcga tttctttcaa atcaccgact
     1801 ttgttttcga tattgattga cttgtagtct cctgtagatg aatgatttaa ggaagtaatg
     1861 atttcctgat actgctggat atagttacga aaacttctat ttaataattg atgaatagca
     1921 agaataaaca aactcattaa taagaaaatc atgattgcca gacctaataa ggtttgtgac
     1981 gaataatttg gattttcata tacttgtaat gtgtggttac cgatagctat ctgttgcgtt
     2041 tttttccatt tagaaggcga gatgtcttca gataaattga cggaatcaat accattagac
     2101 aaagaataat tgtaatgtgt tggaaagaga ctctttttta gcgcgttgat cgaaacgtct
     2161 agaatcaatg tagcatcggg catgtcctca ctaatgaaac ttaatgaacg aataaaagaa
     2221 attttttcgt tttttgtagg tgcgtaggca cttaagtatt tttcgtaatc taatgagata
     2281 gatatatttt taacttcatc atcttgcaca agttttttta agttatctac taaataggta
     2341 ggggagcgat cctttgacaa aatatcttcc atgtattcag caggtgatga gaggtagtag
     2401 tcattaaggt tttcttggaa atcataattt tgatagatct ctgtcacgat accggagaga
     2461 atacgattat atgtttccat atagtgggtg atttgctgaa tgttttgcag gttttgattt
     2521 ttttcttttt caatcacatt gatataggaa aagaacaatg tgaaacaggc aagtaaagta
     2581 ataaaaaaaa tcaatatgta tgtaaaacgc ataataactt ttgataaatc gtttttcatt
     2641 caaagtcctc attttgataa tctctaattt tatgaatcat tatagcacat attacaagtg
     2701 atgtaaacgc tttgcaaaca gggctactta tgattgtgaa tacagtttcc gtttaaaaac
     2761 tattctattg tagaggttta ataaactaaa aataatgtat aaaaaattaa tgtaagcgat
     2821 taaccaagtg ggtataatca aggaaacgct gagagaggag agacaaaatg aagctaaaga
     2881 aagggttatt aggaaatcta aaaaaaaacc gagcattgtt tattatgctt ttaccaggtg
     2941 cgttatggtt atttatattt tgctatatac caatgtttgg agttgtaatc gcttttaaag
     3001 atttcagaat ttcatcaagg ggattcttta caagtttgtt caacagtcct tgggttggct
     3061 gggaaaattt caaatatctc tttgcttcgc aagatgcttg gatcattact cgcaatacgg
     3121 ttgtttataa cgttgtaggt attttgctaa gtactttttg tacagtgtca ttagcaatca
     3181 ttctgagcca aatggcgaac aaacggttat tgaaaaagat gcagacattt atgatttttc
     3241 ctaatttttt atcatgggta gtcatcagtt actttgttta cgcatttttg agtacggata
     3301 aaggattaat taatatttta ctaagcaatt ttggtgtgga acccataaat tggtatagtg
     3361 aaccgaagta ctggcctttt attattgttt ttacgagttt atggaaaggc gtaggctatg
     3421 gatccatcat ttattacgcg tcaattatgg ggatcgatac tagttattat gaagctgctt
     3481 tagttgatgg tgccagtaaa tggcaacaga taaggaatgt agtcttgcca catttaagat
     3541 cgattattgt cattatgttg attttgtctg ttggtagtat ttttcgagct gattttggat
     3601 tgttttatca attgccaaga aattcggggg ctctttatga tgtgacgaat gtattagata
     3661 cttatgtcta ccgtggatta atgaatagcg gagatatcgg aatgtctacg gcagcgggat
     3721 tatatcagtc atcagttggc tttgtcttga ttttgattac taataagata gtcaacaagt
     3781 tagatcctag ttcagcacta ttttaggagg aatcaaaatg atatcaaaat taaaacggca
     3841 gatgtacttt tcgctgccag tcgaacggtt tttcacaata ttactaatct tatttactct
     3901 tagctgtatt tttcccttta ttttcgtaat cgtcatttca ttaacagatg aaaaagcatt
     3961 acaactcaac ggttacgaat tattgccggc tcaatggagc actgatgcat atcaatactt
     4021 aatacaagat ggcggacagt tacttcggtc attaggcgtt acaattatga ttacagtgat
     4081 tggaacgttg attactgttt ttatgacggg aacctatgct tatgttttat caagagcctc
     4141 tttcccttac cggaagttct ttacttttta tctttttttt accatgttat ttgcgggagg
     4201 gatggttcct tcttacttag tgatgacgaa gatgcttggc ttaaaaaata caatttgggc
     4261 tttgattcta cctcttgctt ttagcccata caatgtcatt attttaagga cattctttaa
     4321 gaagtcgatt ccagaatcga ttatcgaatc cgctaaaatg gatggctgta gtgagtttcg
     4381 agtttttttc caaatcgttt tgcctttagc gatcccaggg gttgcaacaa taggtttatt
     4441 ttcaagctta ggttattgga atgactggtt caacgcattg ctgtatattg acaccaacaa
     4501 attgattcca ttgcaatatt tgttaatgaa gattcaaaat tcaatggaat tcttagcaaa
     4561 taataatgac attacattag cgcagcaaca agcaattcaa aatagccttc ctcaagaatc
     4621 aacacgaatg gcaatggtcg tagtagctac tttaccgatt gcaattgttt atccgttctt
     4681 ccaaaaatac tttgttcaag gattgacgat cggtggagtg aaagaataaa aaagaatagg
     4741 agatgttaaa agatgaaaaa gaacatgcag aaatatttga ttggtggtgc ttctgtacta
     4801 acccttggcc tattaggtgc ttgtggtagc agtaatggcg aagcaaataa tgaaacagga
     4861 accacaaaag ttacttggta tcaggttgga gaagaaccca aagattttga tgaggtcatg
     4921 acaaaagtca acgaaaaatt aaaggaagaa atcaatgtag agttggatat gcggctgatt
     4981 ccggacgggg attatcagca aaagcttggt gtgatgatca attcaggaga agaatatgat
     5041 atttgtttcg tcaatggcac agattatgtg aattatggga acaaaggtgc tttcattagt
     5101 ctcaacgatc atttggataa agagttgaaa gattatgcag ctgaattgaa tgaaggattt
     5161 attgaaggtg gggcaattaa tggcgaaact tatggattgc cagtcaataa cgatattgcc
     5221 acaacggaat attggacctt taataaagat ttggtagatc aataccaatt ggatgtagag
     5281 aatgttgaag gtgtagaaac attggctcca gtattagaaa agtttgcaga aaaaaatact
     5341 gatacgaata ttacgccaat cggtatgacc cgtaccagtg tctgtattcc ttatgacaat
     5401 attatcggtg gtggtgtacc gctagcggtt gcatttgaag gcgatacaca aacagttgtt
     5461 aatacttatg agactccaga aatgatgact tatttgaagg ctatgcatga gttttataaa
     5521 aaaggatata ttttgaaaga tgcagccact gttacgacag atccatttcg aattgatagt
     5581 aaaaactggt ttttaggtcg taactcaagt ggttatcaac cattagcaca aaaaaaatta
     5641 gaagctctag cgggacatgg attaatttta aaaccagctg gaaaagcttt taaaacgact
     5701 ggatttgcaa gagtggcaat gcatgcggta tctgcttcaa gtaaacatcc ggaagcagcc
     5761 ttgaaattgt tgaattatgt gaataccaat caagaagtag cggatttaat ggtttatgga
     5821 attgaaggaa aacactatga tcgcaatgaa gatggttcga ttactttaac aaactctgat
     5881 gattattatc aaggcgcttg ggcattggta aatacttatc tagtttcaaa aacttcaccg
     5941 attacagaag aaagtaaaaa actagaagaa gaaagtaaaa agtttcaaaa tgaagcaccg
     6001 atgtctccta ttttaggttt ctcttttgac gcttctgatt ttcgaacaga aattgcaagt
     6061 gtacaaaata tcgtgtcaca atatgaagta cttttaagct cgggaacagt tgaccctgaa
     6121 caatatgtac cagagttgtt agaaaaacta gaaaaagctg gattggataa aattcaggca
     6181 tctgctcaag aacaatacga tgaatggcga aaatctaaca aataattttt tactaaatga
     6241 aaagaataga ctaagcagtt agtgggggga ttcaaatgaa cgaaaacaaa tggaccaaag
     6301 gatttaattg ggtttttcaa ttgttgttac taaactttac ttattttata ctaatttgtt
     6361 taggatttgg aattttaggt tttttccctg ctacgatagc tttgattgct ggcgttgtga
     6421 atcgaaaaaa atatggcttg caagagtctg tgaagttcat gagtaaaatc tataagaaaa
     6481 attttgttag atataatcta tattgctggt cagcaacttt gttgttggcc ggcaatatta
     6541 ctacgatctg gctttgttgg cagcaaagcg caccattgtt ttatttatta agtacattat
     6601 tatcggtaat tacactgttc ctagtctttg caatgttgaa ttgggtcgtg atcaaaagtc
     6661 ttgggttgtg gatgatggga gaccgactga ttgactattt gcttttcaca gcaacgatgt
     6721 tgccaacggt agtcatgcaa ggcttggtgc ttggaattta tttccgaata ttgatgattt
     6781 tgcctgtgat ttttctgttt ggcggaacag ctgtaacggt aatattgatt agtaaattaa
     6841 ctgaaagagc gttagcaaag ttgccttgtc agatacaatc gcactaattt tttcacaaaa
     6901 aggagtattt ctttctatga agttaactga taaacaagta gctaatatag cctttatcca
     6961 gcaacttgag attccattga cacaaaaaga tgaagaacaa atagacttga tttttactga
     7021 cacaaaggct aatgtgcgac aaatcaagat tactaaaaat gagcagcaac gaatttgctt
     7081 gtcttattca catgaagact tgctgtatcg aggattgttt atctgccttc cacgtttttt
     7141 agctcaagga ggagagatgc catacattga agaaacctcg atcattgaga ccagttattc
     7201 attagatgct tctcgtaatg gcgtgatgaa taaagagact ctaaaaaaat tcatttctta
     7261 cttagcgttg atggggtaca acacattgta tatttacaca gaagatacct atgaagtaga
     7321 agaccttcca tattttggtt accttcgcgg agcgtataca aaagaagaag tgaatgaaat
     7381 tgttgaattt gcttctggtt ttggcataga agtagttcca tcgatccaga cccttgctca
     7441 cttgacccaa tttttgaagt ggtatgctca acaagaactg atggatgatc aaaatactct
     7501 actgatcggt gaagaaaagg tttatgcggc aatcgaaaag atgattattg cctgcaaaga
     7561 aatgtatcag acagagcgta ttcatttggg aatggatgaa gcctatcaag caggtctggg
     7621 acgatattta agcctgtatg ggtattgtga tcggacaact ttaatgattc aacatatgga
     7681 ccgtgtgtta tcaattgttg ataaatataa gatgaaacca atgatttgga gtgatttcat
     7741 ttataagcta ttagatgaaa ccggtaaaga taggtattac aatcctgatt ttaaactcaa
     7801 agcattagca gctaaaggat taccagcagg attaacctat gttcattggg actatggttc
     7861 agatgaagtt tcctcctatg agaaagtaat tgataaccat ttgaaatttt gtgacattga
     7921 tcattacgtt ttagctagtg gtgcccatat ctgggggaga ctagccccga atcatgggaa
     7981 aacagaagca attgtttctg cagctgtaaa agcttctaaa aataaaggtg tacgttctgt
     8041 gatgttaact acttggggag atgaagggca ggaaacagag cattggcatt ccttaattgg
     8101 ggcattaaaa ttagcagatt atgtctattc tgaagaagag tggaatgatt ttgaggaaat
     8161 ctacgatcgt ttattaggaa caggtagtta tcaattaatg tccgaattac gatatttcga
     8221 tgaagtggat accattacaa ataacaactt acaaatggct tccgtgagta aactgctact
     8281 ttggcaagat ccgttagttg gtatatatga ctttcatgta gccgctcata acaaaattgc
     8341 cactagaaca attggtactt attatcatga gttagctcag aaattagata tgaataaaaa
     8401 ttggaatcca aaacaaccaa ttttaacaac tattcgtcaa cgatatatac ttttagctga
     8461 aattttagca caaaaggcag aactaggcat ctatttacaa cactgctgtc tggtagaaga
     8521 ccttgcagga ttaatggaat tagcgaatcg gtgtgaagca ctagccaatc gagtaaatga
     8581 attggcatct attcatgaaa taatttggta tcaaacatac aaaacctatg gttgggaagt
     8641 attagaacaa cgatatgctg cattagctca tcgtctgaaa accgttgcgc gtcgtattaa
     8701 aaatcatctt caggggcaag atgccctaga ggagcttttg gaagaacgat taccgttttg
     8761 tcaatatcaa gtgccgcttg aaatttctgg ctttaattat cggcaaagct cggtgtcagg
     8821 ctacaattaa cgaaggaatc ttcccgttga acggaccact tgctcatcta atgggaaagt
     8881 ggttcgtttt ctattcataa gtagcttacc actaactctt ttattaagaa gagaaaaaaa
     8941 gtaggaagtg agaaaatatg ttatcggact attatcaaaa tctgtcagtt ataagtgtca
     9001 atacagaacc attacgtaat tattatattc cttatgcaag taaagaagaa gcaaaacaag
     9061 agttagaaag ggaaaaaacg agccagttta tcgatctcaa tggtacatgg gattttcagt
     9121 attatccttc tgtccaacag ttaccggaaa atttttttca agaggccttt actgaaagct
     9181 atgatagaat ttctgttcct ggagtttggc aaacagaggg atttgactta cctcagtata
     9241 tcaatgtatc ttatccaatt ccttttgatc cgccttatgt acctaatgat accccttgtg
     9301 gtgtatatcg gcgtcagttt caaattgagc aaacagatgc acgcttttac ttaaatctag
     9361 aaggagcaga tagtaattgt tttgtttgga taaatagaaa ctttgtaggc tatgaccaag
     9421 tgagtcatag tacatctgaa tttgatgtga ccaagtattt acaggttggg gttaatgaaa
     9481 ttcaaattct agtgatgaag tggtgtgatg gtacctactt tgaagatcag gataagtggc
     9541 gaatgagcgg tctatttcgt ccagtgtatc ttcttcaacg accaactatg catctgacaa
     9601 gttatcaact acggacgttg actgatccta aaaaaggaag cggaacatta atggtttctt
     9661 ttcaacgatt tactcctatt gaagtatcgt tacctatttc ttacgaatta ttccatcctg
     9721 atggacgtct catagcgaaa ggggagtgtt actcggaaca acaaataaat ttggatgttg
     9781 aagattgcct tttttggaca gcagaaacgc ctaaattata tacattactt ttaacatgta
     9841 atggtgaata ttttaaagaa aaagttggct ttcgagcact gacgatcaag aatcgtaagt
     9901 tattgctgaa cggaacacct attaaattat atggagtcaa ctatcatgac gtgaatcagc
     9961 aaggcacgcc agtgatgacc cgagagcagt tacgtgcaga tttgttatta atgaaaaaat
    10021 taaatgtgaa tactgtacga acggcacatt accctaaatc accagatttt tatgaattgg
    10081 cggatgagat tggtctgtat gtaatcaatg aagcagattt ggagtgtcat ggtgtggtta
    10141 atctatatga tactgaagcg aattatcaac taattgctaa tgatccgaca ttcgaaaagc
    10201 cgattatgga ccgagtgatc cgttctattc ttccttatca aaatcgaagc tctatcatta
    10261 tgtggtctat ggggaatgaa tctggttatg gagtaaattt tgaaaaagct caagctttag
    10321 cacggaaatt ggatgattca cggttgattc ataatgaacg ctcgattgaa ccagttattg
    10381 accaagtgaa tgattttagt aacttggatg ttattagtca aatgtatccc ccactggaag
    10441 atgttcatcg tcattgtcaa agaagtgata ctgaaaaacc tttttttatg tgtgaatata
    10501 gccacgctat gggcaacggt cctggagatc ttaaaacgta cttcgatttg attcaacagt
    10561 atgattcctt tcttggcggt tgtgtctggg agtggactga tcatgcaatc aatagaggaa
    10621 ctttagaaac gccatcttat ttatacggtg gtgattttgg tgaaaaatat cacgacggca
    10681 atttttgcgt agatggttta ttgaccccag atcggcaatt aacagtaggt gcattggagt
    10741 accgtaatat tcattcgcct attcaactga ttgctgtaga tgaggagctg caagaagtaa
    10801 ccttgagcaa tataactgct tttacagccg gttcagcatt taacctttct cttgaatggt
    10861 atatagatgg aaaaaaaaca gtttatgaag taatgaatcc tttcatactt gagcctggca
    10921 aaagttgttc attgcccatc acagtaccta caacgattca tggtgctcat acggttgctg
    10981 tttcgctatc tgtttataaa aatgatgagc tttatggaca gcaacagctc tttcttaaaa
    11041 aagaaaaaat gagattgcca agaactgctc atcataatga tgcaccacaa atttcagtaa
    11101 aaggcacaga gctgataatc aaaggagaat cctttattta tatatatcaa ttagcaaaag
    11161 ctgcgttcac ttctgtaaag atcaatcaaa aggaactttt ggaacgtcct actcaatttt
    11221 caatttggcg tgcaccaacg gataatgatc gtaacttagt aaacaaatgg aaagcagctg
    11281 gatatgctga aatgtcttta gaaatcagaa aaaaagactg gaaattcgta gatgatcatc
    11341 tcctgatcga aacgtcttat cgaggagtta ttccaggatt acagccaatt tttacaatgc
    11401 acatacagtt gaaaataaat ggtgcaggcg taatcaacca aaaagtatca gtggagaaaa
    11461 atccgatttt tccagatttc cctcgctttg ggatggactg gccgttgaat gatacttttt
    11521 cgaaggtttc ttattgtggc tatgggccgt atgaaagtta tcctgataag cactatgctg
    11581 cgatgtttgg tatttatgag atggagattg aggaatttga tcagccatat atcaaaccac
    11641 aagaatatgg taaccgctgg caatgtgatt gggtatcaat caaaaatcat caaggatcta
    11701 ccatgacggt ttatggaaac tctaattttt ctgctctgcc ttatagtcaa gctcaattaa
    11761 ccgaaaagtc acaccattat gaattaataa aagaaaatag aacttggttc aatttaagtt
    11821 ataaacaaaa tggtatcggc tcacacagtt gcggtcctta tttagaagat cgtttccgtt
    11881 ttatggaaga tacttttgac tggaatatag tgattacttt caaaggagaa aatagatgaa
    11941 agaaacaaag atcaatcaag tcaaaaaaaa attatctcgt tatcaagaag ttgtttatcg
    12001 aaaccattgc ttaaaatggt caaaaaataa gctgaatgtt cgttttaatg gattatttta
    12061 tcgtttcgaa cagttagaag aagtctggaa accggtaacg aatttccaat catgtcctgt
    12121 acagctcata aatgatccaa aagaaacata cgatttatgt ataacacacc tttataacca
    12181 gcatttgaaa aatgacggat tttatttaaa ggttactaat gacaatcaac ttacgattga
    12241 atcagcaaac cttcgagggt ttcaatatgc tatggaagcc ttattagaga gttttttttc
    12301 ggtaggagat caattattat taccggaatt gattctgaaa catgaaccat cagtgaaaat
    12361 tcgaggaatc attgaagggt tttatggtat cccctggaca catgaaatgc gcctctctct
    12421 tttttcatat atgaaagata accaattgaa tacttttatg tatgccccta aagatgatga
    12481 attattacgt aaaaaatggc gtgaactcta cgatgcgcaa gaattagaca aatttaagga
    12541 gcttttatct gctgctgagg ctagcaatat cgatttttgg tacttaatta gtcctggaaa
    12601 tgatattgat attacgtgtg aagaagacat tcaagttctt ctgaaaaagt tagaacaact
    12661 gattgagctt ggcgtatttc aatttggtct attaatggat gatattgact atcaattaaa
    12721 aggtgctgct aaacgccgtt ttcgagagcc agcattcgct catgcctatt tagtgaatcg
    12781 agtagaggaa tatcttagca ctcggttgtc caatcatgaa ttagtcattt gtcctacaga
    12841 atatgataat cgtcatggtt ctcgctattt agcaacgtta agtcaagaaa taccagaaca
    12901 attaccgttc ttttggactg gcccaagcac gttagcggcg tcaatttcta cagaagagct
    12961 gcaggaaatg gcttctgtct atcaacggcc gatgctgatt tgggataata ttccggtaaa
    13021 tgattattta gaggataaag aactattgtt catgagtcca tatgagaatc gaacaccgaa
    13081 tctttctaag gagagatacc aggttacagg agtagtttcg aatccaatgg ctcaattaga
    13141 agcttcaaag tttacgatca atagtatggc taattactta tggaactgtg agcgttttga
    13201 tcctttggaa acttggacgt cagtcgttga aaaagtagtt ggaagtaaac tacaaccagc
    13261 ttatcttacc ttaaccaatg cttttccaaa tcattacaca agcagtctgc tttcagatga
    13321 agaattactg ctagccaaag acccagaatg ggtcacaaaa gaaatggctg ctttagtcca
    13381 agcagtaaaa tggatccagc aagaacaaca tacatctaga ttgagaacag aattggagcc
    13441 ttggttacaa gcaatcacag aaagttggac tttctggcaa gaatggcaat taaaaaaaga
    13501 tccaaaagaa gcagaagaat ggttggctaa gaaaaaaaca caccgcatag gacgtgattt
    13561 agtaactgcc catttagagc aaattatcaa aagttagata tcttaaaaaa taaaaagcaa
    13621 gaaaaaggag aacaaaatgg tcaagagatt aattagtgca aactacagtg atgtcaagaa
    13681 aatgacgtca aaagagttga agcaatccat caaagcgagt gaaggacggg tgattgtttg
    13741 tgaaacggtt gctaatactc ttccacaatc tggagaaatt acgaatgcag aagttgcgtc
    13801 agcatttggt gcagatttga ttcttttaaa tggtttcgat tgttatcgtc ctgcagtttt
    13861 tggactacca aatgtgacga ttgagaaggt ttttgatcta cagcaaacga ttgaaaaccc
    13921 gattcctaaa ttaaaagaac tagtcggtcg tcctgtggga attaatttag aacccattgc
    13981 ccctaaaaca aatatgatga gtgagaaagt agaaatcagc caaggaagag caagctctgt
    14041 tgaaacgata caaaaagcag aagaactagg agtcgatttt atttgcttta ccggtaatcc
    14101 aggcactgga gtaaccaatt tagaaattac taaatccgta aaaatggcaa aaaagtattt
    14161 ttcgggattg attattgctg ggaaaatgca tagcgccggc tcagaagagc cagttgtgaa
    14221 taaagaggcg attatttctt atgcggaagc aggcgcagat attttactag ttccttcagt
    14281 agggtctatc ccaggctttt tagagcaaga cctaattgaa gcggttcggt tggcaaaaaa
    14341 atatgatttg ttaacgatgt ctgcaatcgg tactagtcag gaaagtgccc gaccagaaac
    14401 attgcggcaa ttagccatta tgaataaaag ttgtggtgtt gatttacaac atattggaga
    14461 tgctggatac gggggattgg caccagcaga aaatattttc gaaacctcgg ttgcaattag
    14521 aggaatgcga cataccatca actgcgttag ccgctcgatc aatcgctaac aaaattaaat
    14581 aaaaaatggt taaattgatt atttaagtgg gaacatactt gagatatcag ctaacttctg
    14641 tcactttaaa aaagggactg tgacagaagt gaaaatagac aaaaaatatc cgaacaagag
    14701 actaggatag cagaaaaact atcgttttgc aacgaggacc aactggaccg taggagcaat
    14761 tctcttattg ttcggatatt tcgcttgttc aaggacttat gtctgtagtg cccttttttg
    14821 gtaggaaaaa tggtagggaa ccatatcatt tttaatgaaa atcaagcatt tcaaaagt
//
LOCUS       DACGDM010000058        14569 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.060, whole genome shotgun sequence.
ACCESSION   DACGDM010000058 DACGDM010000000
VERSION     DACGDM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.060"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(374..736)
                     /locus_tag="IXR05_001902"
     CDS             complement(374..736)
                     /locus_tag="IXR05_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260394.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(810..1190)
                     /locus_tag="IXR05_001903"
     CDS             complement(810..1190)
                     /locus_tag="IXR05_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAQ4260395.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1272..2447
                     /locus_tag="IXR05_001904"
     CDS             1272..2447
                     /locus_tag="IXR05_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4260396.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2524..3108)
                     /locus_tag="IXR05_001905"
     CDS             complement(2524..3108)
                     /locus_tag="IXR05_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4260397.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3309..4307
                     /locus_tag="IXR05_001906"
     CDS             3309..4307
                     /locus_tag="IXR05_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4260398.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4419..4928
                     /locus_tag="IXR05_001907"
     CDS             4419..4928
                     /locus_tag="IXR05_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAQ4260399.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4958..5617)
                     /locus_tag="IXR05_001908"
     CDS             complement(4958..5617)
                     /locus_tag="IXR05_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAQ4260400.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5619..6383)
                     /locus_tag="IXR05_001909"
     CDS             complement(5619..6383)
                     /locus_tag="IXR05_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAQ4260401.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6391..7068)
                     /locus_tag="IXR05_001910"
     CDS             complement(6391..7068)
                     /locus_tag="IXR05_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAQ4260402.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7105..8490)
                     /locus_tag="IXR05_001911"
     CDS             complement(7105..8490)
                     /locus_tag="IXR05_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAQ4260403.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8700..8784)
                     /gene="ffs"
                     /locus_tag="IXR05_001912"
     ncRNA           complement(8700..8784)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IXR05_001912"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8807..9322)
                     /gene="tadA"
                     /locus_tag="IXR05_001913"
     CDS             complement(8807..9322)
                     /gene="tadA"
                     /locus_tag="IXR05_001913"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAQ4260404.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9429..10286
                     /locus_tag="IXR05_001914"
     CDS             9429..10286
                     /locus_tag="IXR05_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAQ4260405.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10367..10702)
                     /locus_tag="IXR05_001915"
     CDS             complement(10367..10702)
                     /locus_tag="IXR05_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260406.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10769..12139)
                     /locus_tag="IXR05_001916"
     CDS             complement(10769..12139)
                     /locus_tag="IXR05_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAQ4260407.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12217..12753)
                     /locus_tag="IXR05_001917"
     CDS             complement(12217..12753)
                     /locus_tag="IXR05_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4260408.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13062..14543
                     /locus_tag="IXR05_001918"
     CDS             13062..14543
                     /locus_tag="IXR05_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4260409.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4485 a         2898 c         2366 g         4820 t
ORIGIN      
        1 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
       61 atgtcgttag taacatgtca ataactattt tttaaatttt ttagaaatgt gatataacat
      121 ccacttcaga atcaacgctg ttaaatttat catgtatttc ttccttggtc aactataaat
      181 taagcattac tttgtgaaat gatttttcga tcaattatta ttattcgtta tacaaccgtt
      241 ttcaacatat tttgaaaata aaatgcacta aaaaactatc tttagcagaa catttcattg
      301 tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa aattcaaact tctttgttcg
      361 cttaatctgt attttagaag aaaggcactc cctctacttc gtaagttcca agaacagagc
      421 gcatttgacc tggttcttcc caaatatatc cttcgcctaa ttcttctctt tgattctttt
      481 gttcagtttc aaagacaaac aacggaacat tttcctcttt aatatgtgta tttgtcaatt
      541 ccatcaaact aatcttgcta acatcgatat gaactatttc ttttaagaaa ttaagtatat
      601 tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc aaattccaac ttgtcatcaa
      661 ttgaatggac caaaaatttt ttagtaccat cctccaaatg caacataatt gtaccagcaa
      721 ctcttttgct tgccaaaatt tccacctcga tcaacttgtt ctatggctta cataaaaatt
      781 ctagcacatt ttcagaaaaa atacactttt tatttcttat tttctttccg ttctagttca
      841 gataatgctt cttctatcca aataggtaac tgctccgcaa tagtggtaaa tccgatctta
      901 cgatttttat tcgtgaaata cctttttctg cgatatggaa cagctggatt tgttttttct
      961 aacgttctta aagataaact gatttttttg gaatattcat caatgtcgat gatctgaact
     1021 gttactggct gtccgacttt taacaatgaa tggatatttt tcgtataacc ggattgtact
     1081 tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag aaacgaatgc gccataaggc
     1141 tgtatccctg tcacttttcc ttcaattatt tgtccaattt tataagtcat ctacttccct
     1201 ctcttcgcat ttatcattat actgtaaata gctcaaaaaa agaagcgacg aaaatgactg
     1261 gaggtcttaa gatgatcgaa tttgataaac agatttcaag aaaagataca gaaagtgtaa
     1321 aatgggacgc aattgctgag acatatcaaa tggatgactt acttcctttg tgggtagcag
     1381 atatggactt cttgtctccc ggtggggtag ctaaagcgtt tagtgaatac atcaaacatg
     1441 gaatctttgg ttatgccact ctgtctgata aactatatca ggctatcatt cattgggaac
     1501 gccaacacca tgctgtggag ttgacgaaag aaaatatcgt ttttacaagt ggtgtgttaa
     1561 ccagtttagc tgcagcagta caaactttta caaaaccagg cgattctatt ttgattcatg
     1621 acccagttta tcctccattt tcctctatta tagaaacaaa tcaacgtcac atcgttcgaa
     1681 gctctttgct agaaaaaaat aatcatttca tcatggactt gtctgacatg gagaaaaaaa
     1741 tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc tcacaatcct ggagggcgtg
     1801 tttggagcaa agaagaattg aaacagttaa gcgaattgtg tttaaaacat caagtgattc
     1861 tgtttagtga cgagatccat caagatttaa ctttattcga tcatacattt acttccatgc
     1921 taacgattga tcctaattta gatgatctac tagttgcttt tacttccgca accaagactt
     1981 tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa aaatccagag atgaaagctg
     2041 attttgaaaa acatttagtg atgaaccaac agcacgaaat caacactttt ggactgattg
     2101 gaacccaagc ggcttatgag acgggtggag aatggttaag ccaactgatt ccttatctag
     2161 aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta tcttccgaaa gtgagaataa
     2221 tgaaccctga aggaacttac ttaatgtggt tagattttac cgcctatatt tcagacgacc
     2281 aagaattgga gaacactctt gttcggaaag gaaaagtcgt attaaatcct ggcatcacgt
     2341 ttggtccttc cggtcatggg catatgcgct tgaatattgc ttgtccagaa gaaactttac
     2401 tggaaggact taatcgaatc aagtatgctt tagagacaat cgattaaatc atttattcaa
     2461 aataaaagga cgagacctta ctaggtttcg tcctttttca taattactcc gtaccatacc
     2521 aaactattct gaaatttcaa ttgtttcaat cactacatca tgtacaggtc ggtcttgtgg
     2581 accacgttgt acatttgcga tttcatctac tgtgtccatc ccttctagta catgtccaaa
     2641 gactgtatgt cggaaatcta gccaaggagt tccgccacct ttatacgctt caatgatttc
     2701 tgatgggaat ccagcacctt ctagttgtcc aagcatatta gctggcacat ttgtgttatt
     2761 tacaataaag aattggcttc cgtttgtgtt tggacctgaa tttgccatag ataaagctcc
     2821 gcgaaggttg aacagttcac gactgaattc atcttcaaaa ctttcgccat aaatactttc
     2881 gccacccatt cctgttccag ttggatcgcc gccttggatc atgaaatcag gaataacgcg
     2941 gtgaaaaatc acgccatcat aataaccttt tttggaaagt tcaatgaaat tttgaaccgt
     3001 cttcggtgct agttcaggga ataattgaac agtaatgtca ccacggtttg ttttgataac
     3061 agcttttggt cctttttcac tttttaaatc tagttgtggg aatgccatat tgtttcctcc
     3121 taatatttgc atacttcata ataataataa cataatacct aacctctcgt aaaaatacta
     3181 gatttgtttt cttttatttt tcatcactag atacattcta taacttaccg tttcgatttc
     3241 gaattcaaac atttttgaga agcattctca attaaattct gctatagtgt gaaaagggag
     3301 gaatttttat ggaaatctat gacattacaa tcatcggtgc aggtcctgta gggatgtttg
     3361 ccgcttttta cgcaggaatg cgccaagcta aaacaaaaat cattgacagt ctacctcaac
     3421 ttggtggtca attagcaact ttgtatcccg aaaaatatat ttacgatatt cctgggtatc
     3481 cagcaataaa agcaagtgaa ttaatcgatc aattagaaaa acaattaact acttttaacc
     3541 atacattcca tttaaaagaa gaagttctct cgcttactcg tgaagacgaa gttatcgaga
     3601 ttactacaaa taaaggcatc cattattcca aagcagtcat tttagcttta ggaaatggtt
     3661 cattccagcc aagaaaattg aatttagata atgctgaatc atttgaaaac cacggattgg
     3721 attatttcgt gaatgatttg atgaagtatg ctggaaaaaa agtcgctatt gctggaggtg
     3781 gtgattctgc tatcgattgg acgttgatgt tagagcctat tgcaagcgaa gtttacttga
     3841 ttcatcgtcg cccggaattt cgtgcgcacg aacatagtgt atcacgcttg aaatcttcat
     3901 ctgtcaactt gcttactccc tatctcatcg atggattatc aggcaataat ggggaactga
     3961 cagatatccg gttaaaaaaa gtgaaaagtg acgagacgat tgatttgatg attgattctc
     4021 tgatcgtcaa ttatggattc tcttctaatt tagaacatct ttcttcttgg ggacttgata
     4081 gtaccagaaa tgccattact gtaaaatcag atatgtctac ttctattcca ggcgtttatg
     4141 cagctggtga catctgtacc tatgaaggaa aagtgaaact gattgctact gggctcggtg
     4201 aagcacctac tgcagtgaac aacgctttac actatattaa tccaaaggaa cgaactcagc
     4261 ctggtcacag cacaagctta tacgataaaa atcttcgtcc tagttgattt tttatatctc
     4321 tttgcatttc aagttaaacc cgaaagcagt ttcttgcatt tttttcatgt tccgttaaca
     4381 tgaaatagag aaagaaaaaa taaaggggga gcaataatat ggtcgtcaaa actgagactt
     4441 tagaagaaaa ggcaagagaa ctattgaagg aacgtggcgt aactgtagaa gatatcgcac
     4501 aacttgtcat gtttttacaa aaagactata tttctgattt gactttggcg gattgtactg
     4561 aaagtgtcaa cagcgtgcta acaaagcgtg aagtacataa cgccattatc actggaatcc
     4621 aattagatat attagcagaa aagaaaaaat tgatgagtcc gttgcaacat attatcgaag
     4681 atgacgaagg cctttacggt atcgatgaga tcctagcctt gtcaatcgtg aatgtttacg
     4741 gtacgatcgg ctttacgaat tatggttata tcgacaaggt gaaacctggt attttaaaag
     4801 aactaaacag ccacgatggc gttcatgtcc ataccttctt agatgatatc gtcggagcga
     4861 tcgccgctgc tgctgccagt cgattagcac acaaagaacc agaaaaaaga agtcgcctta
     4921 ctcaataatt caacaaaaaa agaaagaaaa cgtctattta gacgagttct ttcttttttg
     4981 tttgtttcaa gctatttttt cctaagaaaa gaaaaacagc aaaaaataat tctaataata
     5041 caaaaaataa gataaagcta tgcatgaaaa attcttctgg aagtacattg atgattggat
     5101 cagtaacggg atcgaataac cagtcatcgt tgttgaaaaa cgtttcatga aaaaggataa
     5161 aaaagcgatc aaatcctatc atcatgaaaa aaccgaaaac aactggcagt aacatgccga
     5221 tttgaaacgg acgaatcaac cgccaaagcc gatcattctt ttgcaaatat ttgataaaca
     5281 aaatactcgg gatcaaagtg atgaaaaaca cagcataatc cactaaaaac aaaattttca
     5341 cttcataaaa gtgatgggct ccgctagcag aaactgggaa atctggcaag ctgaggatgg
     5401 ttttgaaggg attattgaga taattcatta ggtgatcaaa atttttcagt aacgtctctt
     5461 gatctaaaga agtataatcc aaaatttgca aatgtccgat atcaaatacg tatagtggtc
     5521 gaaagttgat cgtcacacca actgccagac tgatcagtgt cagaaatagg ctgaacaatc
     5581 cagcatattc catccactgc catctcgaat ttttcatatt agaagctcca ttcatccagt
     5641 gattgtttca cataggtagc tgggataggc aacccaggta catcttcttc ttttgtaaaa
     5701 cctgataaaa cgagcaaagt atctatatta ttgcgtatcc cagcttggat atctgtttca
     5761 tagttatctc caaccatgat tacttcttct ttttgcagcc ctaatacttc aacggcttta
     5821 tccataatga tggcttctgg ttttccgatg tagatcggcg gcgtttgggt tgctgtctct
     5881 acaaaagaga tgactgaccc tgctccagga agaaggccgc gttcagtagg tatattctta
     5941 tctgggttcg ttccaatgaa agtagcacct ttttgaatag caagtgttgc tttaactact
     6001 ttttcatagg tcagataatt atctaagcct accactacat agtcaggagc ctcttcttcc
     6061 catgtaaatc cggcagctaa aatcaagtca atcaatcctg cttctccgat aacatagact
     6121 tttttccctt ttccatctgc tttcataaaa tcgattgttg ccaaagtagc tgtgtagact
     6181 gtctctggag ctacatgaat gtcaaactca tctgctagac gattagctac tgtttctggt
     6241 gacttagtcg tgttattggt aacaaacaag aaaggtaatt ttcttttttg caattcttcc
     6301 acaaatcgtt taccggccgg tatgggttgt gtcccacgat aaatcgttcc gtctaaatca
     6361 attaaatatc ctttatagtc cattcatcca ctactcttcc ctttttctga tcgtaaatgc
     6421 tgtttttgtt ttttctactt gtttaggttg ttcttgtttt tttacttttt cagaggtttt
     6481 tgctgactct gtttttcgat ttttaataac cggttttttg cgattagatg cgactggtcc
     6541 ttttttctca tcgatatacg cacgattatg gttttttttc ttttttcggc gctgagttgt
     6601 cttttctttt ttaccgccga ttctctcgat gacaaaatac gcacaaccaa aattgcaata
     6661 ttcgtaaaga tagtcttcca aggaatcgat tcgctgatct ggatgcgccc gtcgattatc
     6721 cgcttggaaa aatcctttta ggcgtagttg ttcataaccc caatctccta cgatataatc
     6781 atatcgggct agtacatcac tgtaacgttc tccaagcttt tctgcattaa atccttcacg
     6841 ataatcggac acaagccgat aatgtctttc acctatcaaa aaattactgt catctaacag
     6901 tgtcactagc tcgcctttga ctttttctgc tttaggctcc tcaacgattt cttccaaagc
     6961 agctgtcagt tcttcggtga ctgttgtttc ctgttcagct gatgattttt tcttagcaat
     7021 ttctgtttta tgctcaacgt tctgctgttc attttgtttt gcagacatgc gttcaccacc
     7081 tatctttttt attatacctt gtttttattt gattgggtag tgagctttca agtaatctcc
     7141 taccacactt cggataaatt cagggaacaa aaattcattt tttccagcaa tctcaatcgt
     7201 tggaaaaaat ggaacaaaca tcaaatgatc tacggtagta aaagtataat ttttattcag
     7261 atcgattggc ttgttcttcc aaaagacttg atggttaata gaatcatatg tgattccatt
     7321 atagaccatc tgcccaaaaa tcttaccgcg aaatcccatt cccttcatag gatagttacg
     7381 taaaaagtta cgattttttt ctatttctaa aactaagcgg atcagatcat ttccacccaa
     7441 tgtgacattt aacaagtgca tcggatgcgg caacgcagtg tgaagctgat cctgattgac
     7501 ccgccctttt ggaatttcag ttaaaaacag accactgttt aatattgctg cttccgtctt
     7561 tcctcgttct ttcaccgcct caaaggctac ttggataaac gaatgctcat tgaagatatc
     7621 tagactcaga gaaaatggca aatctgctac ttctttttct tttaataatt catgcccacg
     7681 ttctagataa ctatttattt cttgttcatc ttctgtaaaa gctgtcattg tttcggtagg
     7741 gatggctttg gctgaatgct taaggatttt tttctcttca tcgatggtta aatggacttc
     7801 accgacatac tgcccgtact ttccagcggc tgctatttgg acatcattga ttacgtgacc
     7861 ttctctgaat aaatgatggg tgtgcgatcc taaaataaca tcaattgctg gtatttcttt
     7921 tgcaatttgg aaatcatcct gaatcccgag atgactcatc aaaactaaaa catccacttg
     7981 tgaacgtaaa tcttcgacta attctggcaa aatatcataa ggattccgta tgtcccagcc
     8041 attcggatta taagtaagcg gaaatggagc agtaaatgca attagtccga ttttcgtctg
     8101 gtgtttcgtt gtaatgattt tatatggttt cgtccatgcc ggtggctgga gcgtattttt
     8161 atcgaataag ttatccagga tgatatcaaa ctcagcatga tcgtataaat gattcaactc
     8221 ttctttggaa tttcctacgc cttcattgtt tcctatcgtc gctgcatcat aaccaacttc
     8281 attcatcagc aagatatttt cctgtccatt cgttgcttct gacaatggat gccaacgatc
     8341 cacaaaatca cctagatcta ctgcaatcgt tgtcgttttt tctttctttt cgttttctcg
     8401 tttacgttga tccaaaaacc ttctgatcct tggccaattt tctaaatgag aatgcagatc
     8461 attcgtatgt aaaatcacta ttttttccat gtaccctctc gcctctcttt atctttatca
     8521 taccataggc agctttttct tccattgaaa caagctctat ttcagagttt ttcctgcctt
     8581 gaagcaaatt gtataagtac aatattcgat aaatcagtct ggctaaaaaa tcaggaacat
     8641 tcatttttac agtactataa aaataaaaaa aacagacccg aaagtctgtt gtcgtttcat
     8701 tataatcaga cacatggcgg aacctgctta gtgctgcttc cttccagacc tgacacgctt
     8761 cacaagccca ccattgtcct agcctttcgg caaagaatag tataccttat ttttcattcg
     8821 ttgaccagtc tttttttaat ttcttttttc gctggcggag ctttcggaaa aagtcagtca
     8881 aaatcatccc acattcgtct tctaaaatgc caccttctac atatgcttgg tggttaaacc
     8941 gctcgtcctc caaaagattc atcaaggtac cggctgttcc gccttttgga tcatacgcgc
     9001 cgaaataaac ttctgctaca cgagacaaaa tcatcgcgcc gctgcacata ggacaaggct
     9061 ctaaggtaac aaaaagtgca gcatcttcca agcgccagct tcccactttt tcacaggctt
     9121 ccttgattgc aagcatttct gcatgtgtag tagcatcttg cgtggtttct ctaaggttat
     9181 atcctcttcc aatcactttt ccatccaata caaccactgc tccaatcgga acttcatgaa
     9241 gcatttctgc tttctttgct tctgccaatg caaggcgcat ccatttttct ttttctactg
     9301 catcaagatt tgtatttacc aattaccctt ccctgccttt gttttttctt gttttacttt
     9361 agcatatgat aaaaaggctg taactaactt ttttttctat ggtaaaataa atacaagagg
     9421 tgaacaagat gaaaatggat aaattacttg ctctttaccc acaagcacag aaaaaaaact
     9481 ctccagcatc agaagcggat atcctttctt ttgcaattga tgatgctttt atctggatca
     9541 aacaagattc attatctcaa caagaaacca gccttttgaa agcgttattc cctgtaatca
     9601 acgatcaaaa aaaacaccca tggtatcgct atctttttaa agatgcttct tgtgttcaag
     9661 aaaaaagctt tcgtttgatc cagcttcacg tcgaatcaaa aggagaattc ttaaaaaaag
     9721 aatggcaaga tactattttg gaattatttc gctattctgc tgatttcttt ttttatacag
     9781 acacagatgc gctcttagtc gaacaaataa accgtgatta tcttgatgct actgaaatca
     9841 acggtatttt tctatcttta gatgctgatt ttgatacgac aacgtctgta ttcgttggtt
     9901 ctttccattc acctggcacc gacctcgtcc ctttgtttgc tgaagaaaga aaaatttttt
     9961 taacagagca aaacaatctt tatactcaca gccgtacttt ttctatgcaa gatgtggctt
    10021 tacattacta tacaaaagat actgtaaaag atagtaagtt gatcaaaagt tacatagaac
    10081 tgatcaaaca aaatgaaatg gaagtgatca ttcaagaatt atggaatgaa ttaggcaatg
    10141 tcagctctgc tgcaaaaaca ctgtttcttc atcgtaatac tctaaaatat cgaatcgaaa
    10201 aatttcaaga acagtctggt ttcaatctaa aaaaagccaa cgatttactg ttttgctatc
    10261 ttttattgct tcatgaacat aattaaagat agattaaagg ggttgtgaca ataattttgt
    10321 cacaacccct tatttcgaat gaatagtgtt caaaagctag tttctcttac atcatttttt
    10381 caacaaaatg cattagccgg tcttttacat cttcggttga atctttgatt gaatcaccat
    10441 aaacagagat tttctttttt cctgatttga tttttgctaa cattcccatc aaagaatcca
    10501 agtcactatc tgaaagacca tctacgattt ctagtaattt ttcatttcca tcaaatttgt
    10561 catagacgaa tttttttact ttcgtccgag tagtcatatg atggatcttt tccattactt
    10621 ttcccgatac aacgactgct gtcgctacac tggcagcggc tgctacgctt aatccgattg
    10681 ttacttttgt tgatgttttc ataagtatca gctccttttt atctatctcc atcatagcat
    10741 agacaaaaaa ataaacgaac taatccactc agtgaaatct caatccttta gggaaaaagt
    10801 tctttactgt tccttttact tgtttcccaa atccgacagg tatcttatct aatactagca
    10861 aaacccatcc ttgattccca tcacgttgaa atgtttctcc tgctgtgtaa gattgccatt
    10921 ccttttgagt gatcggcaag caaggtatat tctctatctt ttttgtagca agcgctaatg
    10981 catagctagg ttcaaatcga ttctttttga aatctcctaa atgcaaacct gtacgtacga
    11041 cttttaaacc atcgagagaa ggggctaact caggaacttc ccaaagatgg tcgttgaaca
    11101 ctaaaagtct tccagtagct tcataatgaa aatcatttga aaactccgtc cagagttttt
    11161 cctgctcttt tgtcatttgc actttacttt tttttcgtgt cttcttttct ttatgcatct
    11221 gattttgtcc atgaaaagtc agctttgcaa caaaatgtcc ttcaccctga tctttatgag
    11281 gccatatacg tattgttttt tccaaaccag ctacgcttcc ccattcagaa cgtcctgaac
    11341 taacggattg agtcaaagga atctcctcaa tcgttactgg ataattttct acaagccagc
    11401 taatgatctc ttcattttct tctggtgcaa acgtacaagt cgaataaatc agttgtcctt
    11461 tattttttag catttttatt gctgaagaca aaatctcttg ctgacgtttt tgacagtata
    11521 gcggagattc ttctgtccac tcttttattg catttggatc ttttcggaac attccttctc
    11581 ctgaacaagg agcatcaacc acgatccgat caaaaaagcc cgaaaaatga gggacaagtt
    11641 ctgcgggtgc atgatttgtc actattgcgt tcgaaactcc ccatcgttct atattttctg
    11701 ataaaatctt cgcacgtttc ggaaagatct cattcgtcac taataaccct ttccccttca
    11761 tttgagcagc taattgggtt gatttaccac cgggagccgc acacaaatcc aaaacttttt
    11821 caccgggttt tgctgcagca gctgttccaa cgatcattgc acttggttct tggctatatt
    11881 catacccagc ttgatggagg aaagactttc cattgacagt gccaagaaat ccctcattgc
    11941 tgtagggagc gggttgtaat tcttcgctat ggtaagtttg gaccatgtcc aatcctgccg
    12001 gttttagtgg attccaccga aatccttttt tcacgcttcc ttgttcaagc gcagaaaaaa
    12061 aatcggatgc ttcttcgcct aaaagaagac gatatttttt gataaattgc tgtggtaacg
    12121 ttgtcgcttc ctccttcatt ccaatgtttc gttagacatt ttacaatctt ttttacgaaa
    12181 aataaaggtg gctgatctac tttttcatgt tgctgcctaa ggtgactgtt cctttaagat
    12241 attttccaag tattcatccg tcacctcgtt tttatcccaa acagcgttca tcatttcaag
    12301 aaaatcttga gaagaatcat ctgagcgcaa acttcccaat gcattaagcc ataccaattc
    12361 aagcgacttt tcttctttga tcttcgtgtg acctttgaca tatgagaaaa atggccgctt
    12421 aaatagcgaa tccatgtcta aatcagattt tgcaatgatt tcacgaatac tttcatggat
    12481 agaaaaaaaa tctttcaata agtagacaat gcttaaaaca tcatcggaac tgcattcagc
    12541 taagtagttt tcaaaataaa cagtgatttc ttctaatatc ttctctttta acccgctgat
    12601 tgatttgaaa tgtgtataaa tcgggtatgt agaacaaccg cagaactctg ctaactctct
    12661 tgcagtaatt gacttcattc catattcttc cacgtatacc atacttttga acagcaaata
    12721 ttctttacta taatttgtta ctctccccat cattcttacc tccgtctctt ttcatctacc
    12781 cataaataaa taacataaat aattctaaaa atattattga taattatcaa aacatattta
    12841 gttatatcca ttaaaaatca atttttccgc cttaaaaaca agaatatctt gacaaaatac
    12901 cctaggaaat aaacaataga ataaacaagg taacaaaaaa attaaataac gttatataaa
    12961 aaagaaggcg acactctgtg agaataacac agactgaaat gactttccac tcacagtttt
    13021 tgtctaacta tatacaaaaa cagaataaaa aggaggtatt tatgctaatt gaagcaagaa
    13081 aaaaagagtt acttgttcta caaatggtca ttcaaaaaaa taattgttct ttacaagaat
    13141 tatccaatga cttacatatt ccaaaacgga caatcaaaga actgatccga aaaataaatg
    13201 tatcactcaa gcaattttta ttgattgatg aatttattta ttctaatcat aaaggagaga
    13261 tccaaaccaa agaaaccgat caaactaaaa agttagctgt tttttctaag ttaaaattat
    13321 gctacctaaa agaatccaat cgttttaact atttgatgtt actaatcaat tatccacaaa
    13381 ctgctgtacc aaaaaaatat ttacttgaac aactttatat atcgccctcc tatctcgaaa
    13441 aactgacaaa acagctcaat cattccttaa aaaaattcca tttacggatc ctatctgtaa
    13501 aaaattgctg tactcttgaa ggaaatgagt tatctatccg tctctatctt tacttttttc
    13561 tttcagatac atttggaggt aacgattggc cattttcctc acttgaatta aatgcactaa
    13621 aaatgaacag tacagatgag caaatagaaa aaatttcaaa acaagaaaaa aatatctact
    13681 tgctgttaac tttattcata ttacgaaaca aacaacaggc atattttcca aaaacttctt
    13741 ctgaaatcac tgaattgatg gacttattgc agcatacaca tgattattca gaatacttta
    13801 cttctttttc agtgagtcgc ccttgtgaag agacagaaac agagagagcc tactttaatt
    13861 attttttcta ttgttttttt ccaaatcaaa tctcttttcg acaaaaacag gagattggtt
    13921 ttttattttc cacaagcaaa aaccttattt gtcgacaagt cggtcaattg atgacttact
    13981 taactcaaca gtttcctctc aaccatttag aaaataaaat accaatttat ttttattttc
    14041 ttgtgttggc agttgttttt ttcgaactgt tgggtgaatc cagcagtagt ttttctacac
    14101 tttgctttcc agaagccacg tccaatcatt ctagttcttt tatacaggaa aagaaattaa
    14161 gagaaaaaat cgatacaatt ttttcaaaaa atggggaaag aaaccaaatc agtcaatacc
    14221 ttagtcaatt gatccaacac ttactacaaa cagaaacgaa agagcagtta ctcatccatt
    14281 tgcagataac caaacagttt acaggaaatt atcatcttca aagccatttg cagcagttat
    14341 ttcgcaaaga tgctgttaaa attaccgcat attcagaaca tgctgatttg atcattacag
    14401 atcagcatga gaaaatttca gatgaaacgg agactttcta tctggataca acgcacaata
    14461 cagtgttatt tggcaagtta ataaaagcgg ttcatgaact gtatatgaaa aaaggttatg
    14521 agaacaaaac aaagaggatg tgacaaaatt cttgtcacat cctcttatt
//
LOCUS       DACGDM010000059        14362 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.061, whole genome shotgun sequence.
ACCESSION   DACGDM010000059 DACGDM010000000
VERSION     DACGDM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.061"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(22..933)
                     /locus_tag="IXR05_001919"
     CDS             complement(22..933)
                     /locus_tag="IXR05_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4260410.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1390..1818)
                     /locus_tag="IXR05_001920"
     CDS             complement(1390..1818)
                     /locus_tag="IXR05_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260411.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(1846..2484)
                     /locus_tag="IXR05_001921"
     CDS             complement(1846..2484)
                     /locus_tag="IXR05_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260412.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(2488..4524)
                     /locus_tag="IXR05_001922"
     CDS             complement(2488..4524)
                     /locus_tag="IXR05_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAQ4260413.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4650..5315
                     /locus_tag="IXR05_001923"
     CDS             4650..5315
                     /locus_tag="IXR05_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4260414.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(7250..10399)
                     /locus_tag="IXR05_001924"
     CDS             complement(7250..10399)
                     /locus_tag="IXR05_001924"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HAQ4260415.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(10412..11629)
                     /locus_tag="IXR05_001925"
     CDS             complement(10412..11629)
                     /locus_tag="IXR05_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAQ4260416.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(11619..13214)
                     /locus_tag="IXR05_001926"
     CDS             complement(11619..13214)
                     /locus_tag="IXR05_001926"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAQ4260417.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            13339..14124
                     /locus_tag="IXR05_001927"
     CDS             13339..14124
                     /locus_tag="IXR05_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HAQ4260418.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
BASE COUNT         4411 a         2752 c         2266 g         4933 t
ORIGIN      
        1 catatttttt atttataccg cttatttact acttgctgta ctagaatctg aagtgaatgt
       61 actcaaaaca ttttcaaagt ctttgtcttt gatttttaca ttagcgtctt tcaatacttc
      121 gccaattact ttattctgga aggtactgtc acttaatttt gtgtctgttg caatttcttt
      181 caattctttt ttgtatttat ccatgtcgtt gcctttgttt tggtttttca ccattttaac
      241 cacataatat tccgtagtat aagttgaagc attggtagaa gtgatcacat cagaaacttg
      301 accatctttc aacttaaagg ctgcttcttt gacttctgcc ggaaccgttg tagtagtgga
      361 atcaaatttc acttttccgc catcttcttt tgtcgtagta tcagttgact tgtctttggc
      421 taatttagag aaatcgtctc ccttatcagc agctttcttc acatcttttg catcatcttc
      481 acttgctact tggataattt gagcttccac ttctggatgg aaagattccc aagccgtttt
      541 taaatcttca tcggtcaatt tgatatgttt ctttagacct tcttgaaagg ctagactttg
      601 tttgatactg tctttgaatg tttgttctgt gtaacctgca gatttcaatt gtgaatcaaa
      661 tgaatcaccc aattgtttct ttgtttgatc atattgagaa tcgatttctt tggttgatac
      721 gtcatctcca tatttatctt caaatacttg ataaacgatc aactgttgca cagcggaatc
      781 tgctccttgc atttttttca agctatccat tacttcttgt tcgctgattg taccgccttt
      841 ataactaacg gctgtttttt caccggcatt cgtacagcct gacaataagc cagtgcctag
      901 tacgatggca agtgctaaaa atcttttttt catttatcaa ttctcctact tttcgttttt
      961 tgcgaattgc taaaaacaaa ggtgttcaag atgaaaatca tcaagaacac ctttactaat
     1021 ctgctcgata cgtcctgaat agatataagg ctacacaatc cagaaagttc gctcagcaga
     1081 ataaatgtca agtagcacat cacaccttaa tatactactt cttttgttac cgtttttcaa
     1141 gtctatcttg cgttccgtat ttaacgtaac taattcttag aacaaatgtt atcgattttg
     1201 tttttcttct tccgctgctg ggatattcaa atcagacact tttatgttcg attttccaga
     1261 catttttttg ttgtttttat tatgatatat ttttatacaa ctaaaaatga atatattaaa
     1321 actaccaaaa ataactttta acgctgtttc attatatgtt ttttctattt tatataaact
     1381 tttggatact taataccaac cggttggatt gtaccaacat gagaatgtgt cagttctatt
     1441 tcctgtcgca cttgcatagg cccatactcc ttttgttgca tttgctgatc gaatagagtt
     1501 tccaactttc gcttttgcac cgtgacgatt atagacacga ctatagtggt tagaatgacc
     1561 tgtttttctc gtacaagttg tatcactata ataaacccat cttccagagc tatgattaat
     1621 tgctgttcta gaaatttccc ggtctactgg taaatttgac ttaataatat tacctttagc
     1681 atcaaaatga atctctcctg gctttaaaga tttgtaatag atttcaccgt gaactgaatt
     1741 tgcttccact tcagatgaca tagcgtttcc tccaacaaaa cctatcccta gtgcacaaat
     1801 aataactgct tttttcataa aacgacatcc tttccttttt gatttttaaa gcatgatctt
     1861 cttgtttcct attttggtca gatatggatc atgcgtgact acgataacta acgtaccttg
     1921 ggaagcttgt tgcgataaga tttcaactac tttatcctta tttcttttat ccaatgaccc
     1981 agtcggttca tcggctaaaa tgattttgct attcttcaat aagactctcg cacaggcgat
     2041 tctttgcttc tcaccaccag ataatgtgta gataggcgta cttagcttct tgtttatatt
     2101 tacttttttc aatgcctcat actttgctgt tcgcttatct gaaacattta aattcgaaaa
     2161 cttcaatcca atatctaaat taaaatcgat tgtttcatat tcaatcaacc caaaatcttg
     2221 aaaaagaaaa gatatggtat ttctttttat caagcgcttc tctctcccag ttaattgttt
     2281 cgtctcttga tcgaacaaat agaattgtcc tgaactgaac tgatcattca atcctaatat
     2341 attcaataac gtacttttac ctgctccact ttctccaaca acagtcacaa gatccccagc
     2401 atccgcagtg aaacgatcca aatgaagaat cgttttgttt cgaatgattt ttttcgcacc
     2461 ttttatcact atcaacggct ccaattgtta acctccattc atcagcaata actgactttt
     2521 cttttctgta gacaaaataa aaacaactga aagaataaaa tcaatgaagc taaagaaaaa
     2581 aatattaaaa agatatttag gctctctttc tataagaaaa aggaagatta cacttgtcgt
     2641 tccccatttg atgaggttca tcatgaagaa atctttatac gtttcaaaga gcgaataacc
     2701 acttgaacga aagatagcga ttttccgaca attgtagaca aaatatatgc ataacatgac
     2761 atagctcaac aagaagaaag aaaagaaagt gagtaaaaat atctgtatca agtaatgaaa
     2821 tgatctgctt aacactttga cagctatctc ttcagtctga gtatacggaa atgataactg
     2881 caagttatca cgtaactgac tttcttcaat cagctcaaat aacctttctt tcgacaaaga
     2941 gcctatcttg atctttaacg gtggatagat ttctccgctg agaatatttc tttccaaata
     3001 catactgttt ttcaatgtca gtatttcaac aaccggataa tgttcgatcc aggggataga
     3061 aggaataaat gtataaatgg gttgattgtt ttttataaat agaaatttcg gttctttttc
     3121 actgatttct tgataatatt ctgttatttg cgccaggtca ttttttaaat ctgtatgtct
     3181 atatcgttca gggatcaata taacagggtg cgtttctttt tcggttattt ggatcaacct
     3241 tccagagaca tcaatcaaag gaaatttctt aagataattc agatttattt ttatccctct
     3301 gccaaactgt tcattttctt cattcaagta atctgataca ttgactaata tacttccgtt
     3361 tttattcaaa gtttcatata attcctgatc tgctgctgat gcaaaacgat tggaataaat
     3421 aaaatccacg tggtttttcc cgatggttac tggataaaat acatgatagt cctcaccagc
     3481 gatttctttt ggtggttcat gggaaacagc taactgtgaa gaagaaaaaa cgatagttgc
     3541 taattcgaca ttggcaacgg tcaaaagaag agaaaacaac aatccaaatg taaaaagaat
     3601 gtattggata tagttgaacg cttctcttaa cgaagcgatt ttttcaacta ataaaagaga
     3661 aatcaaagag ataccatata ttccgctgaa caagaaaacg tacatctgga acaaataaag
     3721 aaattgctcc ttataataca taaaaataaa accaccaatg attcctgcaa ttatgaatgt
     3781 aataatgatt ttctttttcc ccaataaaca ccacaatact tgatgtaatg aaaagtcatt
     3841 attcaacaat aaactgattt ctttattcat caataagaaa aaggatgata acaaaaggaa
     3901 taaaagaatc aatccaatag ttaaatacac tcgataatta tatacgtctg tatttgaaat
     3961 aaccgaatac gaatagctat tttcaaagtc ttcaaaaata ttagtggcat aatcagtgtg
     4021 aaatgcttga ttgaatcgat cagtgaatag tgaaatgaac cgttcatagg cttctttttc
     4081 tctcgtcatc aagaaaaatt caccttcaaa atcttttatt ttgatcgatt cttcaatgga
     4141 cgttacgcga aaggaggtat tagaataggg taccttctcg tgagaagatt tgacatcccc
     4201 ttgataatac aatgtcattt caagctttgg ctgtatcttg aagttccaag atgtatctac
     4261 ttcattggat tcatttactg tttttttcat ataagaaagc tcagtttctg atgagacatt
     4321 ttcaaatacc atgattagct gctcatattc ttcttgccca ataaaatgtt gtggcaatcg
     4381 aatcggagta taagtatctg tttgatggaa aaattcattt gtccgataga gtacctgttt
     4441 atttatacta accaaggcaa aaccactcat gataccggtc actatgattg tgagtaaaac
     4501 tgtgaacttt tttttgatta tcaccactct cccttactta aatgattctt tgataaaatc
     4561 ataccgtttt tcatcaaaaa aacgtatcta tcaagtgtat aggtcatgta gaataaatct
     4621 atatactgta gaatcgaaag gagaagaaga tgaacaccgg agaaaaaata cgaacttacc
     4681 gcagaaattg taagcttacg caaaaagaat taggcgaaaa aattggtgtt tccgataaaa
     4741 cgatttctag ttgggaaaat tctcgtacaa tgccagacct tgaaatgctg tcacttttac
     4801 atcatacttt aggtctgccg attgattttc cttctattga atcagctacc gaatcaatag
     4861 aaccaacatt gccagatgaa cctcttgtta acaagaaatc ttattcatca aaacaaccct
     4921 tctcactcaa aaagacacta tctttctttc tgctcgtctt ttgtttggtc tatctttttc
     4981 ttatcaatta tcaatacaaa aatgaaacga tcgatcgatt caatcctttt ttgaaaccac
     5041 aaatcggcta taccacactc cctgtaggat acgtggacaa ttccatcgaa cgttgggtat
     5101 gtaatgatat ctttggccat ggtacatggc tgtcttttca cgctggagag gtagaaaaag
     5161 agaaaaacca tgctgtaatc aaacacaaag gaaaacacgt catgaacgtt cgcctgctca
     5221 cttgggaagc cattccctca gattaccaag aaatcctcag ccaagactat gacgacgcct
     5281 taaaaagaag ccctcaggag ccagataggc attaagtagg agatgaacgt agagatagaa
     5341 aaaatcaatg cacatgatct tatccaaaaa acaggggtac aaattaattg aaaaagcctt
     5401 gagatgaaag ttcctaaata aaaaagttca gaatgatagg tatttctggc ttatagtata
     5461 atatttacgc cacagcctcc caatgattct ttttggaatc ataatcaagg atggacattc
     5521 acaaaaatat tttgctcatt cgatccgaat agattaacga ccaatctagt aagtaatata
     5581 gattggtacg tagtcaagct gcacataatt tagatcaatt ttagttcttt tttatatttc
     5641 tatgatctgc tcatttactt ttatatgatg gcttacagta acataaataa atatgataat
     5701 cgctggtagt ttatccaaga gtactcaata aaatacaaaa tggattgttc aagcgcctat
     5761 cataatgata aaatgaaaca aataaacgat acaaggagga agagactttg agtaatggca
     5821 gaacaatttt ttcattgtaa aaattgttca gttgttaatc tatgggattt cggtagcatg
     5881 ggcatttttt tatagaggaa tcacaccaac ctggccgttt tatctcttgt tagtgggaat
     5941 attagtagga aattttgccc ctcttcacta tcgtacgaac ttttttccaa ctgattctgg
     6001 cctttttctt aaaacaaaga cgcgaaaatt agaaaacatt attgaaatga caattacctg
     6061 tataatcatt ttcttagtta tattcctaaa cgtcttctaa taagaatctc ttaaaattag
     6121 cttgttacag ttagttacct agtttatata acacagttat cttatcttcc ttatcaacat
     6181 cttttgccaa ctctttgtct taaattcgaa acatataagc agagctacga acaccaagac
     6241 tgtttcggct ctgttttttg catcaaattc actcttatat agctgataat ctcggctctt
     6301 taaaagaaat tattttcgct tcattttatt ataaaaaggc taggaacctt gatgttatca
     6361 ggttcctagc ctttatttaa gtattacccc acagaccctt ccatatagat ttttaaatta
     6421 cacactagtt taaactaaaa caaacaagga aaaacttacc atttaatcaa aaaattagct
     6481 catatgaata tattagaatg taaattagac tggtcaaaat ctggtcaaaa aagaggacga
     6541 atacaggtag tcctcttttt tgttattttg atattctaaa tcatttttta ttggattatt
     6601 cccttgttcg atatagaccc aaattgatct atcaataatt atcaaactga gtcatataga
     6661 gacaaaaatt tcaaaaatga cctgttaaat ggtcatcgaa tatcatttaa aatcaatacg
     6721 acggagtcag acacggagtc aaaacaagcc cgctgagagt aaaaaatata cagtcccata
     6781 ggtaaagtgc cacaggactg tatatttttt tatttgagat tacctgaaat gattccattt
     6841 aatttttatc tcattttttc ctactagtta gtatcaaata ctctcctatt ttctcaataa
     6901 actattttgg gttacatggt atctgaaaca gctaaaacct tgtcattata gcaaaaaatc
     6961 actttatctc cgtttcattt cagatacatt tcacttaagc ggattccaaa aaaacaaaag
     7021 aaaaaggaac ccctagttag cctatgcttt ttattggttc ctctcaaaac acggtcatat
     7081 aacaacgggg tggggtaaat gaatgaaaaa ggtggaggaa acattattca atagctgtct
     7141 taaatacttc gttataaaat gtgaacaaat aaaagacatc tatccctatt ttctacactt
     7201 ccacttgact accatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
     7261 cattctcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
     7321 gtgggtattt aaatggcttc gcttctggat gtttggcttt atatccttcg taatccttac
     7381 tgttgataat tgctttcata ttaggaattg gatcttcacc tggtagatat tgcagattag
     7441 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaagacatga atcaaatcat
     7501 cactcgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
     7561 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
     7621 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
     7681 ttcctagtaa ttgatcaata taagttgaat caatatcata caacttagtg gtattttcac
     7741 tataaaattc gatcgttgaa aaatcttctc cttctttttc tggttcttcc tctattaatg
     7801 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
     7861 aagttggaga tttcaccatg tcatcattgt aatcgtcata agtcactaac gattcataag
     7921 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
     7981 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgt ttgaatcttt
     8041 ttttggattc ctgataactt ggataaatca aacctgattc ttcttttgct tttgaataca
     8101 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg cttacgaaac gtcacaatca
     8161 atccttttgt cttatcagga tacgtacgat tcgtacgtga aaaagcttgg atcaatcctg
     8221 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtta
     8281 atagacgatc cactacaatc gctaaatcga tttgtttccc aaattgtttg aattccgctc
     8341 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctaatgacc
     8401 aggaagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     8461 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt ggaaaatcag
     8521 gatcctccat cgttcgtcct tcacgaatga gctgattggg aaactctttt gttaaccaat
     8581 caggctcttt cgtcatctct ttgatggccc gataatactt tttggccatg tcaatggaac
     8641 tcgtggttaa gattgcagat ttcgttggcc tgccatttcg aaaatcaaat tttgtatagg
     8701 cattatctgg acggaacatt ttatgaatga ctttttggat atgttcatct gcttcaaaaa
     8761 cagctgggtc caaataactt tcttttttga caggttccat ttgatcaatc atacgattga
     8821 tctgttctga tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     8881 tctctagtga agtcggctcc acggtgtttt catgctctac ttgaaatcct aagacagagc
     8941 catcttctag cgcattctta atggtatagg tatgcaagac ctctccatac tgatcatggg
     9001 ttgtacgtgc caattgccct ttggcttgtt tccgattctc aggaaaaatc ggtgtacctg
     9061 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     9121 ttaacgctcg atgacactca tctactacaa acacgatatg ttggcccatt aatttttgga
     9181 agcgattggt tccttttttc tcttcttgtt tctttgcata tttcaacgcc gcatctagtt
     9241 tttgacgggt tgtaatgatt acaacatttg cattggcatc tgccaacagg gtttcactta
     9301 attctttggc acttcccgtt ccaacgatca agctattcgc tttggcgttc ccggaagaaa
     9361 tcccagtatt aaattccgaa gcaaattttg taaactctgt ggtggtttga ttatctaaat
     9421 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     9481 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     9541 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg tacttgataa ggatgtaaca
     9601 ccatgagggt tttattgtct tgatcttcac tgacgattgt ataatccgca atcaaacgat
     9661 gagcatccgg gatatttaac acttgtttac aaaactcata taagttttct actttttcat
     9721 tgtctttcgt tcgccaacta aataaaaact tagggtgcaa gtctttcggt aaggcatttg
     9781 caaaataccg agtggtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     9841 tgttccgaaa cataccttct tctgcatatt ttttgatttg gttaaatgcc tgataaacac
     9901 catcttttgc agttacttgt ttcagctcga tttggacaat cggtaatcca ttgattaata
     9961 aggtgacgtc aaaacgtcga tcccgtgctt ctatgttact tccacgtttt gcaatttgat
    10021 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
    10081 agacagaacc caattgcgaa tcttcccgtt caatcgtgat ccgagccatc ccattttcac
    10141 cttttaacca tttcgcagca tcaaatgggg ttttcgttcg cagcagtaat tccgttttga
    10201 tcgtttcaaa ttctttatcg gtcaaaggaa aatcattcag ttctgcttga ttatttgaga
    10261 taattttttg gcgtaaattg acccaaaggt cttcttctga ttttagatcc ggacgatacg
    10321 tccactgatt atgcccttct ccaagtacac gaatcaactg ttcttcgact tctgcttcct
    10381 cacggtgact aattttcatt cttcttccct cctagacaaa catcttttgt aagaagcttt
    10441 ttttcgtttc ttttagtaaa tctaacttac gttgatgaag agcgatcgta tcatctagct
    10501 gtttgaagaa agtaccgatt ttttgttgtt catcctttac aggaacctta acactgatat
    10561 tctcaatatc agaactgtta taagaaggca atgcccctac ttgggagtat cttggcaaat
    10621 ttatagtttc aaacaatatt ttaccaaaat agatatccca agtattatta aataaataag
    10681 ccatggtatt gttatctatt aagaaagggc ttgtgaccaa acgttttcta ttaagcatta
    10741 ttgctgcgcc aactttagca aatataatcg ctggcacatc ttttattggc ttccattttt
    10801 tacgctcaat ttgctcatta gatacataat gatttgcatt tctcatttca tactcattac
    10861 caatgttatt catgtcggaa actttaaaaa atggagtacc ttcagaacca ccttgctcgg
    10921 catcaggaaa tccaattccc gattgagttt tacctaattc tcccaactta cgctcttccc
    10981 aatcttccgt aaaaccagga aaccggattt ctggcacttt tgctccgttt tcagggaaca
    11041 ttttttgtaa gaatcctttt ttcgtttcct tcagcaaatc taacttacgc tgatgaagag
    11101 cgatcgtgtc gtcaagttgt ttgaagaagg tgccgatttt ttgttgttct tcctcactag
    11161 gaaacattgc tactatattt ttaaactttt ttagagacag aacatgttga cctgttccct
    11221 ctgcttgaat agataattgt cgttggattc cattgttaat acgtcttaag aagaagtcgg
    11281 aatcagcaga ttttaaagta aatacaggat aaaaatagct tataatccct ctatcaataa
    11341 tgtcattacg gttaaacaca aacacatcat tatcacttcg actacggaac gtgaaatatc
    11401 ctctaggtag tacaaagtaa ccaatattat tttctgtagt tacttgccga tttgcaaaat
    11461 agtcttcttg caaaactatc cctttttgtt gagatgaagt tagcatagga aattgatttt
    11521 gtacacttgt cttttcaaca taatctacaa cgaagtcccc caacttcctc tgttcccaat
    11581 catctgtaaa tcctgggaaa cggatttctg gttgtgtatc attgctcatg tttgaacacc
    11641 tccagcgcac cttgtaacca cgcttcattt tcaggtgttg tttgcaggga agagatagct
    11701 tctaaaagtt ttttttctag cacttgctgt tcttgtcgta tcttcttgat gtcatttccg
    11761 acatgaacca tatcaattgg ttcttcttct tcgaaagtat ctacatagcg tgggatattt
    11821 aagttatagt cattttcttt gatttcatca aaggttgcca aatgagcgta tttctcgaca
    11881 tcttttcttt cagcgtaggt ttcgaggatt ttttgaatgt tttcttccga tagtttattt
    11941 tgatttttcc ctttaacaaa ttcacgacta gcatcaatga ataatacatc tcgagtttga
    12001 cgattcttct tcaacacaat caccgtcgtt ggaatcgatg tcccaaagaa caagttcgca
    12061 ggcataccga tcacagcata aatactgcca tcttctagta atttttgacg gatgacccct
    12121 tctgcagcgc cacggaataa aactccgtgt ggtaagacga tggccatggt acctgtttcc
    12181 ttcaaatgat agaacccatg aagaagaaac gcaaaatctg ctttggattt tggcgctaat
    12241 ttcccataac gattaaaccg agaatcatct aagaaagtcg tatctgctga ccaattagcc
    12301 gaataaggtg ggttcattac tactgcatca aatgtgtaag gttcatctgt tggccagtcc
    12361 ttattcaacg tatccccatt gcggagattc atttcttcgg cgtcgacacc atgtaaaatc
    12421 aagttcattt ttgctagatt gtatgtcgtt gtatttagtt cttgcccatg atatttaacg
    12481 ttatctgggt gtgttaagta gttacgtacg tttaacatca atgaacctga acccatcgtt
    12541 ggatcaaaaa cactaaagaa tcgtcgttcc ttttgatcga gcgttacgat ttgcgccatc
    12601 atatcagaaa ccatatgagg tgtgtaaaat tctccggctt tcttccctgc ttctgaagca
    12661 aattgactga tcagaaactc atacgcatcc ccgatcacgt ccccatcgtg ttctaaaaca
    12721 tctacatcat tcaatttctt gatgacttcg gtaatcgtca catttcgttg ttgctcatct
    12781 gttcctagtt tttttgattg gagatccaca tcatcaaata acccattaaa ttgattgtag
    12841 gtagatgcca attgcacaaa ggctttgttt agatcgttca attggaacgt tgcttgtttt
    12901 gcttgatccg ctaagacgtt gaaaagatac tctggtgcaa ttgcatatcc caaaatatca
    12961 acgattgtgg caatcagatc ttcttttgat tcttcatctg aaagtaattc acgatacaac
    13021 attgtttgtt tgcttactgt gtcatattcc tctaaggatt catctgctaa aagaaccact
    13081 tgttccaaca atcgatcgga taaatattta tagaaaatca gtcccaataa ataattttta
    13141 tattctgacg catccatttt actacggaga ttatctgccg cactaaataa tttttgattt
    13201 aattctgcac ccaaaaagat acactcctat ctcttattta aagttgctat ataccctctt
    13261 attttagcat actccctttt agaaaaagca aaaaaaaaag aaaaaatctt attcttgata
    13321 acaagctacg tgacgtatat gcctaacaaa aatagaactt ttgaatcaat cttaaatgaa
    13381 ggtttaacca cagaaccggc atccattatt tttgatgaag ttatcgatga cgttgaagat
    13441 agtaagtatc ataaaaattt aaaagaactt ttttattttg cactcaacaa tggaccaagt
    13501 ttgttcactg gtatatcagt acctgatagt gataatccat taattatggc aaaaatttac
    13561 ttaacaaaat ggtgtaataa atacatcagg gataggaata acccagcatt aaaaaaacct
    13621 cttaaaacat ttggcgaaaa agatgctgct ttaactacta gagtagcagc aaatgctaat
    13681 attgatgatc aaaaagtatt gaatgactac ttgcgtggac attttttata tatgagcgct
    13741 gagaacatga acggaagtat tttagaggaa tatttagccg aagtgttaga acctgaaggt
    13801 tggatttggt gcgccggctc tgtatatcga gctgttgatt tctgttattt aggaacctca
    13861 ccaattcttt tacaagtgaa aaataaatac aatacagaaa gcagttcgag ttcagctata
    13921 agagtaggaa caacaattag aaaatggaat cgtttaaata agtcgacaaa aatttctggt
    13981 ttggatagcc ctatccccaa ttggaaagca ttaatagaaa tgactgaagc tagtaaggaa
    14041 ctggcagcta agttaactga aaatagttat ttagcttata ttaatgaaaa atccacacga
    14101 gaattatgga cactcgatga ctaacaatat ccttattagt atctatccac gatacatgga
    14161 aaaaattata aacaaacaaa aaaactttga atttagaaat ttctatctta cctcagatcc
    14221 ttataatatc ttttggattt acgaaacaat ccccaccaaa gctttaaagt ataaattgat
    14281 tgtaaaaaat ccaattacta aacttaagaa aaatcaacac tactttttag gagacgatga
    14341 gtttgaacaa ttagtttaaa ag
//
LOCUS       DACGDM010000060        14300 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.062, whole genome shotgun sequence.
ACCESSION   DACGDM010000060 DACGDM010000000
VERSION     DACGDM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.062"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            43..801
                     /locus_tag="IXR05_001928"
     CDS             43..801
                     /locus_tag="IXR05_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAQ4260419.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            861..1289
                     /locus_tag="IXR05_001929"
     CDS             861..1289
                     /locus_tag="IXR05_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260420.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            1335..1407
                     /locus_tag="IXR05_001930"
     tRNA            1335..1407
                     /locus_tag="IXR05_001930"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1368..1370,aa:Gln,seq:ctg)
     gene            complement(1557..1928)
                     /locus_tag="IXR05_001931"
     CDS             complement(1557..1928)
                     /locus_tag="IXR05_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4260421.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            2143..2328
                     /locus_tag="IXR05_001932"
     CDS             2143..2328
                     /locus_tag="IXR05_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260422.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(2411..2599)
                     /locus_tag="IXR05_001933"
     CDS             complement(2411..2599)
                     /locus_tag="IXR05_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260423.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2623..2886)
                     /locus_tag="IXR05_001934"
     CDS             complement(2623..2886)
                     /locus_tag="IXR05_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260424.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            3044..3301
                     /locus_tag="IXR05_001935"
     CDS             3044..3301
                     /locus_tag="IXR05_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAQ4260425.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(3372..3563)
                     /locus_tag="IXR05_001936"
     CDS             complement(3372..3563)
                     /locus_tag="IXR05_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260426.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(3704..4024)
                     /locus_tag="IXR05_001937"
     CDS             complement(3704..4024)
                     /locus_tag="IXR05_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260427.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(4047..4481)
                     /locus_tag="IXR05_001938"
     CDS             complement(4047..4481)
                     /locus_tag="IXR05_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4260428.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            4816..5454
                     /locus_tag="IXR05_001939"
     CDS             4816..5454
                     /locus_tag="IXR05_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4260429.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(5778..5861)
                     /locus_tag="IXR05_001940"
     tRNA            complement(5778..5861)
                     /locus_tag="IXR05_001940"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5825..5827),aa:Leu,seq:cag)
     gene            6389..6889
                     /locus_tag="IXR05_001941"
     CDS             6389..6889
                     /locus_tag="IXR05_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260430.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(7079..7423)
                     /locus_tag="IXR05_001942"
     CDS             complement(7079..7423)
                     /locus_tag="IXR05_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAQ4260431.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(7577..8497)
                     /locus_tag="IXR05_001943"
     CDS             complement(7577..8497)
                     /locus_tag="IXR05_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4260432.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            8684..9175
                     /locus_tag="IXR05_001944"
     CDS             8684..9175
                     /locus_tag="IXR05_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAQ4260433.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(9199..11574)
                     /locus_tag="IXR05_001945"
     CDS             complement(9199..11574)
                     /locus_tag="IXR05_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAQ4260434.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            11900..12526
                     /locus_tag="IXR05_001946"
     CDS             11900..12526
                     /locus_tag="IXR05_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4260435.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            12549..13253
                     /locus_tag="IXR05_001947"
     CDS             12549..13253
                     /locus_tag="IXR05_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4260436.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            13445..14278
                     /locus_tag="IXR05_001948"
     CDS             13445..14278
                     /locus_tag="IXR05_001948"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAQ4260437.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
BASE COUNT         4329 a         2772 c         2437 g         4762 t
ORIGIN      
        1 tttataatag gaaagataaa cagctgaaaa gggagatttc aaatgaagaa aaaaacgttc
       61 aaaaaactat tgtttctagg gggcacagct gctcttttat taagcggtac aagttattac
      121 ctacatatcc attctccaga acatacaatg aacactgcac aaaaaagttc aacacaaaaa
      181 acgaaaaaga caaaagagaa agcagaagtt ttactagatg ttccattaga gagccagttt
      241 gattctcctt ctttagaaaa tggctgtgaa gtcacttcgc tttctatgct tttatctttt
      301 tatggttatg aaacaactaa aaaccagtta gctgagcaat tggattacgt ccctgttttc
      361 aatgcagatg ggactcatgg cgatcctaat gaaggatttg ttggtgatat cagtggcgga
      421 gactgggcta tggtcgtcta tgttccccca gttgcctccc ttgctcagca aatcgtccaa
      481 acggattatc acacttttcc aaaaaccgat gctcaactcg atgatatcaa aaaagcacta
      541 tctaaaggaa atcctgtctg gacttctgtg actatcaatt ttgaagtccc agatgaaact
      601 gattttatga cttggaccac aaataatgga gaagtaagag tcactcctct tgttcatgct
      661 tgtgtagtca ctggatatga caaagaaaat atttatgtca acgatcccta tggtgtaaaa
      721 aatcgagcag taccgatcaa cgatttttcg gcgattttca ctgcaatggg tggacagatg
      781 ctaactttgg agaaaagcta gtaattcaaa caaaaatccc ttatactcaa gataccaaac
      841 ctttgaaggg agcgtagata atggaaaaat tcacacataa aaaaatggat ccaaatgaaa
      901 ttccgattat ttttgtccgt gactgcaagg gaaatgttca aggtaaagtc tctattaatg
      961 agtggaacga gcgtcgcaga cctgctaccc tcaatgaact ggaaatcaaa ttgtatcgtc
     1021 aatctcttgt ttattacgca gatcaagagt acgagaaagc caccgattta ttgaaatttc
     1081 taattgctcg aacagagtat actcgctttg aatatattga acgtttagca aacatctatc
     1141 atattatgaa tgaacctgtc aaagaatatc agttattgga caccgtcttg tcagtagcag
     1201 aactgattgc ccttcctgct ggattagaaa agaaactagt acgccgcctt ttacgagtaa
     1261 agcaacaact atccgatcaa gaaaaataac ttgcgttttt ttaggaaagt gctatgatta
     1321 ttttgttgaa taaatgggat gtagccaaac tggtaaggca cttgactctg aatcaagcaa
     1381 ttgtaggttc gaaccctgcc atcccaattt gatgtgcttg ctgaaaaaat gaaccccctg
     1441 taaaagaaca atctttttgc agggggatta ttgtattatt tttactactt gtatttagtt
     1501 tacataatta aattatgaat aataaaatcg ggcgtattct taatacaaaa actgatttac
     1561 ccaataattg ctaatgcttt ctccggaact ttttctctag gaacttcctc atacgtttct
     1621 atgtgtgctc ctttattgct aattttcaaa taatgatttt cttttaacac agaaagacca
     1681 ttaaattcaa ccgttcgttc tttcccattg gcatcagcag ctttctgcac ataccttgct
     1741 gtaccatatt catttacttc ctctggtttt tgtgtcttta catagacctc tcctttttca
     1801 actaatggat ttagctgatc aagtatacca gggatttctc cataacttcc ttcagtataa
     1861 tatttcagtc caaatagcaa aataccacta atcgccgcca gtccaatcaa atatttaatc
     1921 actttcatct ttctacctcc ttgttatata ttcagtatat gggtcagtta aagaaattcc
     1981 atccgtccca agttggagat ttttctccta ctttagaagc gagaatcgag tgttttttta
     2041 gtaaaaatga tcgttatttg atattattga cgtgtggata aatcagtttt tctcgttttg
     2101 tccatgtaaa aaatcatgtt gatagcaaag gatgtgttca aaatgaatca agaagaatta
     2161 tttcaaaaag tcaaggaaat gattaagaac ggcaatttcg atggcgcaaa acgatttatc
     2221 gaagaacata aagaacaatt aggaccttat aaagagaaag cccaaaatct tttaaaagat
     2281 gtaaatatcg acagtgtcaa aaacaaattt aaaaatctat tcaaataagt aaaactttca
     2341 cttttgtaaa atcaaaggag gacaatgctg ctgcatcgtc ctcctttggt tcttttctga
     2401 atacttcata ctaaaataaa cgtgtcggat cgtaatgata agtcacattg ccgttcagtg
     2461 aggcttttcc caccacatat ttacgattct ccaacttcag ccacgcttct cgaaaagcca
     2521 ttaattcttc tctttttaca tcaatctttt cgatttttcc atcgatcaaa tcttgaataa
     2581 gttgttcata tggattcatt tttttcctcc atctgctgtc aatcaataag ttgtaaaaat
     2641 aggttcatat gcttttttgg tatctagatc ttctctgact ttgactgtcg tataaataat
     2701 tttttctact gggatactat aataacttcc ttcaccatta ttgaatcggt gaacgtcttt
     2761 ctttgctaaa ataccattta ttttattcgt cagtacacgt tgttcgacac tgttacttac
     2821 aacatagtaa atcacccgaa tattattgat caaatgcaaa tcgatttcta acactacatg
     2881 atccatgaaa atcccactcc ttctttcact ttgattatag caagtttctc ctctaatttc
     2941 aaaatcgata cagattttac cggataaatc cacaaaactg cttgcgccat ttcgcacaaa
     3001 gtgttatttt gtatcatgga ctttatttat cggaggcaat agtatgatcg cgatcggtca
     3061 atttgttttt tatattcctt tttttattat gataagcatt cttttctatt acataaaatg
     3121 gacaaaaaag aagttttcag ttttactggc ctctttacct gctgtatatt ttacttatca
     3181 aattttttct tttaggcatt gggaaacaac gtctgtatta ataacacaca tcatcgaatt
     3241 gacgctttca gtaatttttc ttattatttg gatctatttt ttatataaga atcagaattg
     3301 aatccctcgc atgtttaaaa agaaaacgat taaagatgca gcaaatttct gccgatcttt
     3361 aatcgttttt tctattctgt tataccaaaa aaatgtttga atcggtgaag gatcgttcct
     3421 tgttttaatt ctataaattc ttgtgcgatc gggtactttt cttccaaatt ttctttgttc
     3481 ttttcgatca ggcttttcgc ttcttcatat tttttatctg cacatagtgc ttttacttcc
     3541 tgtaatactt ttcctgcttc catttgcctc accctcttgc cattttattg ctttaagttt
     3601 tatttaagtt atacgcatta ttctagtttc atcccaaata accttttttc atttttactc
     3661 ctcgaactaa tcagttttct aaaggctgat tggttcgtct tttttatttt tcctccattt
     3721 cattctgctc ttctgttaat ttatctaatg ctttgattga tgctgcggct cttgcataat
     3781 catagctgta taattccata aatttatcag gcagaacaaa ccacgctgga tgataaccgt
     3841 tagctgtgac agggaatcct ttatcttgtt ggttatctcc atcccatctc agagcaacac
     3901 ctttttttcc tttccacttt actaaagcga tcgagtatcc cttctttgtt tgtgtgccgt
     3961 cttcaataat tgctaaaatt tctatttttt cttttggcgc acggacttct tgaggacgaa
     4021 ccattttcta ttcctccctt atctcattac ttcacgacca acacactgca aggggcatgt
     4081 gatacgacat aagaagcggt cgatccaact aatgcttgtt gtatagcacc ttttcctgtc
     4141 gctcccataa cgatcaaatc aatattttct tgtccaggga tgacattggc aatcaaattt
     4201 cttggatctc cagtttcaac tattgcgtgg atctcagcaa tgccgtactc tttggcatca
     4261 ttgatttttt tcagcatggc tacttctgtt ctttgttttt catctgcata gatttttgaa
     4321 aaggcatagg cactatgggt cagctcaact ttgttgatga ttgacacgat aaataagtgg
     4381 gcttcattgt cctttgctaa gtcaagggct tcagcgaacg ctttgatcga ttgtcttgat
     4441 ccgtcaactg ctaccatgat gttctggtat cttttactca ttggaaccgc ctcctttttc
     4501 ttttattgta acatctcaag caaaaataca aaaaatatac gcaatatgta aataaaatga
     4561 tgaacaaaag caatttcttt caagttattt atacatttct tttctcatca gaacacctgt
     4621 tctaatccca ttatttctgc attatgtgaa attcctcatc atttttcaca tcgagcgaac
     4681 atcattctgt tacaaaaaac gtggatttgt cataaattgt catgcttctt ttacctatga
     4741 aatattttca cgtgttaaag tattcctcgt tgaacacaac aaataaaact ttttaacgaa
     4801 taaaggagat ttttcatgac atcacttaaa actttacttt ttggaacaac tttggctgcc
     4861 ggcgctgcat tcttcatggg aacgactgct catgcggacg aagcttatac cgttcaatca
     4921 ggtgatactc tatcaacgat ttctcaaaaa tacgttggtg ataactcctt gatcaatgcc
     4981 attgcagaat caaattcaat ttctgatatt aacctgatct actcaggaca acaattaaca
     5041 atcccaacag aaggctctgc acaagcagct gctgaacctc aagcagccgt tcaagaagca
     5101 ccagtccaag ctgaacctgt tcaagctgaa caacctgttg tacaagaaac ggttcaaacg
     5161 gaaacacaag cagcgcctgt tgctgaaaca caacctgctc ctgctgtaac agaaactgct
     5221 gctactccag caagtacaag ctctgcaaaa gaatggatcg cacaaaaaga atcaagcggt
     5281 tcttacacag caacgaacgg acgttacatc ggccgttacc aattagattc ttcttactta
     5341 aatggtgact actctgctgc aaaccaagaa agagtagcag aacaatatgt tacttcacgt
     5401 tatggttctt gggaagcggc gaaagcattc tgggaagcaa acggttggta ctaagattca
     5461 ttatttgaac gtttaaacac attcaaaata tagtaagagg tcatgcgatt tattctttcg
     5521 catgacctct ttttgagttt aagtttagtc tttattcctt aactatcgtt tgccagtatt
     5581 tcttgtatca gaatctataa atctactatt tgaatcaatc tattaggttt taaactgtcc
     5641 caccttcaca caaatttttt ttgatttatt tgaatctggt tccgttgttt aaaatttttc
     5701 ctatattctt ttagataata tgttattttc tttctcatcg ctccaggtgt accttctctt
     5761 tataaaaaaa caaattatgc ggctaagaag actcgaactt ccacgaggtc accctcacta
     5821 gcgcctgaag ctagcgcgtc tgccaattcc gccatagccg catcacatct tttagtttag
     5881 gattacatgt gttttttgtc aagaacatat ttttgttctt tttcatttct gtacgccctc
     5941 ccttatgcca tctacacaaa taattcatcc gagcaactcc atcatctatt gagggttggt
     6001 gaaaaaatct gttttatcca tatgatcgat ttcaatgtta aacgaacgac tctgggatta
     6061 gtaactattt tatttttttc ttcatttctt ttttcctctt tttctcgatt cagctatctt
     6121 ctttcatttg gatattgatt atttcttctg ttgattacta tccttctgga attctagacg
     6181 ctgaagtaat tcacgttttc tttcttctag agatcataag taacgaatga acgaacttca
     6241 aataattttt ttattgtaat tcatatttgt attgttcgat gattcttaat acgatatgac
     6301 acaataaata aaaataggca tggctattta caacaatagt gctatagtag aaaacaaatg
     6361 aataaggtta cttaaagagg tgaatacgat gaaactgatc aaactatggg aagcagattt
     6421 aaagaaagct tatcagctac aaactagctt tggaccaaat gagagtggat ttatcaacaa
     6481 tgcttatggc tatacatttg ctgaattttt agattatgta aaaaaatgcg aaaaaacgtc
     6541 tttaggaatc gatcttcctg agagttacgt tcccgcaacc gtctttattt tagaaagtga
     6601 tgaacatgag tatgtaggaa tttttaattt gcgccataaa ctgaacgaaa cattaagaaa
     6661 cggcgctggc catattggtt acggcatctc ccctaattat cgtaaaaaag gatatgccac
     6721 acaaggatta gcattagtac tacaagaggc aaaaaaaatc ggcattgatg aggcactttt
     6781 gtctgtaaat aaaaaaaatc ttggcagtct taaagcacaa caaaaaaatg gggctgcgat
     6841 ttatcgtgaa gatgagaaag aatactatac gaaaatcaaa ctgatgtaaa aaagaaggat
     6901 tccaaaagga aagggatttg aatgtccttt atcaatagaa cacatttatt taattaactt
     6961 ataatatagc agacaaaatt ttataaacaa agaaaccttt tatctctttt cttctagaaa
     7021 ggataaaagg cttttttgtt tttcctattt gcttctcata gctagtcagc caagatttct
     7081 atcgtatccc caacgcaatc cgtgcataac ggctcatctt atctgtcgtc catgctggat
     7141 accagactag tttgacttct gctttcgtta cttctggcac ttcttttaat gcgtcatgga
     7201 tagattctgt taaaatatct gctaatggac agcccatagt tgttagagtc atcttaatga
     7261 ctgtttctcc attttcagga ttgaattcta tatcataaat caagcctaaa ttgacgatgt
     7321 cgattcctaa ttcaggatca atcaccattt ccaaggcagc aagaatacgt tctttgatta
     7381 gttctatttc ttgtccagac cgttcttggt ttgcttcgct catcgtacga cactccttaa
     7441 cacgattttt atttatcata ctcttttttt agctgcttgt aaatgagaat ttagaagtaa
     7501 gattctcgtt taaatttata aaaatgttct tattagatgt aatagattaa atttattcta
     7561 aaataaacct gattcctcat tttttttgtg aacgattttt tatttctggc aatacgccag
     7621 ttgttcgata cattttttgt tcgttttcat ttgcaaaccg gccaaatact gaatgagttg
     7681 gtaaaatatt gataaatgca tcgtcgtcga tttcatgaac gatctgatca agatcataca
     7741 tttcgtagcg ggtgatgacc atcatgatca tgttcccttg tttttttgaa tagccaccga
     7801 cagacggcag taatgtcatt ccacgtacca tccgttttgc tagttcttct gttacctctt
     7861 ctggcttgac ggtaacgatc attgctgtta ctttttgatg actcgtgtgg atggcatcaa
     7921 ttacttgagt cattgcataa atggaaataa tcgtatacaa ggcactttcc cagttaaaga
     7981 agaagcctgc gatgactaca atgataccat ttagaatcag catgtagttt ccgactgttt
     8041 ttccagttgt ttgtgaaagt acaagagaga tgatatccat cccaccagtt gtaaagccca
     8101 tttttaaaga taatcctacg ccaagaccta ataaaacacc gcctactagg gcattcatca
     8161 aaatattatc agtgatctgt ccgactggaa gcagcatcgt catcaccgat acacatacaa
     8221 cattcacaaa actaaggatc gttgctcgtt ttcctacttt gagaaaccct aatacaaaca
     8281 cagggatatt caaaagaaaa ataaatgttc ctgtgtctat cttgatatga aaccattcat
     8341 ataaaagcga ggaaatgatt tgagcgatcc cattcatccc tgcagaaaag acattggctg
     8401 gaatcaaaaa ataatttaaa gcgaccgcag cggtcaatcc ggttatcaaa ataaccacta
     8461 ttttctttaa tctttcattt ttatgatacg cagtcataat tttactcaca agcacctctc
     8521 ccctactttg gtattccaaa tgtaagaata acagtttatc tattaaaata aaatacttcg
     8581 aactcaaatg agaagaattt tagcaaacag gtaagaatct gccctaatcc tatgataaga
     8641 tagatgtatg gtaaatattt atatgtatat caggagggtt cctatggcaa aagatgctag
     8701 cttcgacatt gtatcagaag tcaatacaga agaagtaaaa aatgcgattc agcaaacaac
     8761 aaaagaattg tccaatcgct ttgacttcaa ggattctaca gtagaaatca aattagagaa
     8821 cagcaatcta gttgtattga gcgatgatga tttcaaaatc gaacagatca aagatgtatt
     8881 atttggtaag ctgatcaaaa gaaatgtgcc aatcaaaaat atccattttt ccgaatcaga
     8941 acacgctcta ggtggcaaag ctcgacaaac tgccgatttg gtcaacggaa tcgatcgtga
     9001 aaacgcgaag aaaatcacta cagctatcaa aaatgaaaaa ctgaaagtaa aagcacaaat
     9061 ccaagaagat cagattagag tgacaggtaa gaaccgtgat gatctacaag ctgtgattgc
     9121 tttattacgt aaacttgact taccaatcga gttgcaattc actaactatc gttaatcaaa
     9181 aaacgaggct gacgtctgtc attcctcgtt tttttgattt actgcttctt ttgataacca
     9241 aaaacgctgt attccttctt ccaattcccc aacacttcgt acttctcttg ctgtttgcca
     9301 atgttgtggg aataaacgtc gataagaaaa actagaaaat cgttgatctg ccaatacaac
     9361 gattccttga tccgccatgc cacgaatcac tcgaccacca gcttgcaaga ctttgttcat
     9421 tccaggaagc tgataagcgt aagcaaatcc aaggtgttcc ttctcatcat aatatgattt
     9481 gatcagttcc tgctcatgat tcatctgcgg caaacctaca cctacgatca tactgccgat
     9541 caatcggtcc cctctcaaat cgattccttc tgaaaaaatc ccgccaagta cgcaaaatcc
     9601 aatcaatgtt tcagcgggat ttgtttgaaa ttttgttaaa aatcgttcgc gttcttcctc
     9661 attcatgtcc gtttcttgga ttagcacatt gctgtcggga tattgctgtc tgaatgcttc
     9721 caccgcaaga tctaaatatt gataagaagg aaagaaaacg aaataattcc cgacctttcc
     9781 atcagcaaaa gcatgaatcg tctctactaa ttttgccaga ctgtgttccc tttttcgata
     9841 agtcgtctct aggtaatttg cgatgaaaac ttgctggttt ccttctggga aaggactcgg
     9901 cagtttgtaa gccagacttt tttgtccccc cagtgtttcc tgataataag agagtggtga
     9961 aaaactagca gaaaaaagaa tactgctttt tcctttatcc aacgactgct caagaaacaa
    10021 gcttggatca atacaaaact cttttactat cagatcgcga tacgtttttt cgactgttgt
    10081 ttcgtagtga tcatcataaa attcactgac cttcaaaaaa tgaagcaaat caaaataata
    10141 aggaagcaat tgttcttgtg atgggtgctc aggaaattct gccagccatt ctttaatttt
    10201 ttcgcttaat tgataacctg cctttactaa agattcagcc ggtgcttttt gatgatgata
    10261 atcccaatga tcttcttttg ctatttctcg gatcgaatca aattctttta atagtttgtt
    10321 gaaacggcga tgaagttttt tgaattcctt tggtatagct tccttacttc gtttcgtttt
    10381 ttcataagat agttctgccg aatacatctc tcgggaacga ttcaccaaat tatgtgcttc
    10441 gtcaatcaaa aacagatagt cctcgttttt ttcatcttca aaaaaacgtc ttaaataaac
    10501 agttggatca aataaataat tgtaatcccc aatgattacg tcacaccaga tactgacatc
    10561 taatgatagt tcgaaaggac aaagtgtatg ctttcttgca taagtttcga tgacttcacg
    10621 agtgatctga ttctcatgat tcaaaagatc ccataaacct tcattaatcc gattgtaata
    10681 accattggca tatgggcact gatctggatt acaggtcgtc tcatctaaaa agcagatctt
    10741 gtctttcgcc gtcaaagtga cactttttac ttcagctcct gtatctttta atgctgtcat
    10801 agcatcttca gctacttgtc tagttattgt tttagccgtt agataaaaga tcttttctcc
    10861 ctcttcttcc cctacagctt tcaaagcggg gaataacgta gagattgttt ttcctgttcc
    10921 ggtaggtgct tctacaaaca atttctgttt cgtacggatc gttttataag cagctaccgc
    10981 tagttcacgc tgacctttcc tatactcatc atgggggaat ttcaaagcca tcaaagaggc
    11041 attgcgtaca gtgcgccagt tttcttgaaa aacaagccat tctttataat cttcagtcag
    11101 ctttttaaaa aaagtttcta actgctctct tgtctgatgt tcaacctttc tcgtgatcac
    11161 ttcttctgcc gtctggaagt aagtcaattg cagatttatt tcttgtaaat catgttcttg
    11221 actatagata taggcataca cccttgcttg atgaaagaaa agttccactt gttctggttc
    11281 taaatcttca aatcgtggtt cggaggtttt gatttcatct atataataaa taccgtctct
    11341 tttgaaaata ccgtctgcac ggccttcaac gatcaggtaa tattcatcta attgaactgt
    11401 tgtttttaaa aagacttctt tttcatagtt ttctcccgca tctttttgga gcttgcggtg
    11461 gattctcgct ccttctaatg cagtatggtt acttttttta cgattgtcga tacttccacg
    11521 tcgcaaaata aattctacta agtgccgcac agatattttt gactgtttga tcatttccac
    11581 cacctctttc tctctaagat tacctgaaaa aacctagttt agcaaaaaga gctctctttc
    11641 caaacataaa aaaacaccct gctgattagg cagggatata ggatatagaa tttggatttt
    11701 tggatgaatc taatgtaaca aggacatatt aaaatgctat gaaaacttac tttccttctc
    11761 tttagaatat ccaaatactt ttcatatagt ctgataattc agataagtaa agagaaataa
    11821 gtacctgttt ttgtttccta gcaatgaatg cgttatacta atggatgaaa gaagttttgg
    11881 ctatcaagga ggaatgcaca tgcatatcga aagattaaaa acaggaatga ttgaagaaaa
    11941 ctgttatttg gtctacaacg aagaagcact tttgatcatt gaccctggag aagatgcgga
    12001 acgaatcaaa caagaaatca aaaaaacaaa ccaacagccg gtagcgattt tgcttaccca
    12061 tactcactac gatcatatcg gtgcagtgga acctttacgc gcgtattatc aaatcccagt
    12121 ttatgtcagc ccactagagc aaaaatggct aggtgatccg attttgaatc tttctggact
    12181 cggtagacat gatgatattg ctgatgttat tgtctcgcct gcagaatatg aatttgaaat
    12241 gaaaacttat actttaggaa acatgtcttt tcgcgtcgtc cctaccccag ggcattctat
    12301 aggaagcgtc agctttattt ttgatgattt tgtcgtttct ggcgacgccc tgtttagagg
    12361 aagtatcggt agaaccgatc tgtatacagg gaatttagaa caattacttc atagtattcg
    12421 gacccagctg tttgtattac ctgatgaatt tgcagtctat ccaggacatg gcgatgcaac
    12481 gacgattgaa caggaaaaaa ggacaaatcc ttttttcaat cgttaaaacg acttaggagg
    12541 agaataaaat gacagaaact acactttata tcgtacgaca cggaaaaacg atgttcaata
    12601 caattgaacg agtacaaggc tggtgtgata cacccctcac aaagcaagga caagaaggca
    12661 ttcattattt aggtcgcggg ttaaaaaatg tcgacttttc atttgcttat tctagtgaca
    12721 gtggtcgtgc aatcgaaact gcccgtatta ttctaggaga acattctaag ggaaaagaaa
    12781 ttccttattt tattgaaaaa aggattagag aatggtgttt cgggtctctt gaaggtggat
    12841 atgacatgga aatgtggggt gtgatccctc gtgtattgaa ttttaaaaca tatgatgaaa
    12901 tgtttaccac agaagtttct tttgaacaaa ttgctaatgc tgtatacaac ttagataccg
    12961 ctgggtgggc ggaaacttat gaaacattgc gagaccgtgt atggacagga tttgaagata
    13021 tcgcccatca ctgcgaaaaa aatggtggtg gaaatgtttt agtcgtatct catggtttga
    13081 cgatcgcctt tttgcttaat ctgatcgatc ctaaacagcc tgttcgtgct gggcttttaa
    13141 atggcagcgt aacaaaggtc acttatgcaa acggtcgatt ttctatccac ggcatcaatg
    13201 atacgtctta tatcgataac gggaaaacac atagtcgcga ctcgtttcta taatggggat
    13261 attttaattt ttaccagaga atcataaaag gcaaagtctg aacgagggct ttgtcttctt
    13321 ttttctcttc gtgtacttat ctgctttatt tctcaagttt ttcttaatat taaaaaacag
    13381 attgggtttc tcaaaaaata acggtatact ataagatgta tcttaattgg gaaggaagga
    13441 atttatgttt tttgcaaata ttatcaaagc agtgattctc ggtattattg aaggaataac
    13501 ggaatggctg cccatcagta gtactggtca tttgatccta gcagatgaat tcatcaaact
    13561 ggatgccagt tcacaattta tgtcgatgtt caatgtcgtt atccaattag gggcgatctt
    13621 ggctgtcgtc gttctttatt ttcacaagtt aaacccattt tctccaagta aatcaacggt
    13681 agaaaaaaaa gatacgtgga cactttggtt taaagtgatc gttgcttgca taccagccat
    13741 catcattggt ttgcctttgg atgattggtt agaagcaaat ttccacaagt tcttaccagt
    13801 tgccattgtt ttgatcgttt acggtattgc ctttattatt gtcgaaaaac gcaacaaaaa
    13861 caaaacacct cgttggactt ctctgaatga ctttacgtac caagcagctc ttcttgttgg
    13921 gttattccaa gtcttggcac ttgttcccgg aacatcccgt tctggcgcaa cgatcctagg
    13981 atctatcttg attggtgctt cgcgttttgt cgctacagag ttttcatttt tcttagggat
    14041 tcctgtcatg tttggcgcaa gcggcttgaa gatcgtcaaa tatttagctg aagggaattc
    14101 attcaaaatg gaagaaactg ttgttcttct tgtaggaaca ttcgtatctt ttgtggtttc
    14161 cgtcttagct atcaaattct tactaagcta tttgaagaaa aacgacttta ccgcttttgg
    14221 ctggtatcgt attatccttg gtatcatttt gattggttat tggtttattg caatgtagaa
    14281 aaaaccagaa cacttctctt
//
LOCUS       DACGDM010000061        14197 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.063, whole genome shotgun sequence.
ACCESSION   DACGDM010000061 DACGDM010000000
VERSION     DACGDM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.063"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            476..1339
                     /locus_tag="IXR05_001949"
     CDS             476..1339
                     /locus_tag="IXR05_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4260438.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="IXR05_001950"
     CDS             complement(1468..3090)
                     /locus_tag="IXR05_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4260439.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="IXR05_001951"
     CDS             3339..3860
                     /locus_tag="IXR05_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260440.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="IXR05_001952"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="IXR05_001952"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAQ4260441.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="IXR05_001953"
     CDS             5941..6759
                     /locus_tag="IXR05_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAQ4260442.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="IXR05_001954"
     CDS             complement(6862..7059)
                     /locus_tag="IXR05_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260443.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="IXR05_001955"
     CDS             7228..7806
                     /locus_tag="IXR05_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4260444.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8851..9354)
                     /locus_tag="IXR05_001956"
     CDS             complement(8851..9354)
                     /locus_tag="IXR05_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4260445.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="IXR05_001957"
     CDS             9713..10738
                     /locus_tag="IXR05_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4260446.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="IXR05_001958"
     CDS             11061..11939
                     /locus_tag="IXR05_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260447.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="IXR05_001959"
     CDS             12415..12531
                     /locus_tag="IXR05_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAQ4260448.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="IXR05_001960"
     CDS             13459..13797
                     /locus_tag="IXR05_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260449.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="IXR05_001961"
     CDS             13891..14121
                     /locus_tag="IXR05_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260450.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT         4504 a         2373 c         2718 g         4602 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacgctt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attacta
//
LOCUS       DACGDM010000062        14161 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.064, whole genome shotgun sequence.
ACCESSION   DACGDM010000062 DACGDM010000000
VERSION     DACGDM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.064"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            66..767
                     /locus_tag="IXR05_001962"
     CDS             66..767
                     /locus_tag="IXR05_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAQ4260451.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            764..1885
                     /locus_tag="IXR05_001963"
     CDS             764..1885
                     /locus_tag="IXR05_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAQ4260452.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1900..3132
                     /gene="pepT"
                     /locus_tag="IXR05_001964"
     CDS             1900..3132
                     /gene="pepT"
                     /locus_tag="IXR05_001964"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAQ4260453.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3264..4172
                     /locus_tag="IXR05_001965"
     CDS             3264..4172
                     /locus_tag="IXR05_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAQ4260454.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4207..4479
                     /locus_tag="IXR05_001966"
     CDS             4207..4479
                     /locus_tag="IXR05_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAQ4260455.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4490..5536
                     /locus_tag="IXR05_001967"
     CDS             4490..5536
                     /locus_tag="IXR05_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAQ4260456.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5787..8396
                     /gene="clpB"
                     /locus_tag="IXR05_001968"
     CDS             5787..8396
                     /gene="clpB"
                     /locus_tag="IXR05_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAQ4260457.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8547..9218)
                     /locus_tag="IXR05_001969"
     CDS             complement(8547..9218)
                     /locus_tag="IXR05_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260458.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(9211..9705)
                     /locus_tag="IXR05_001970"
     CDS             complement(9211..9705)
                     /locus_tag="IXR05_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAQ4260459.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9725..10945)
                     /locus_tag="IXR05_001971"
     CDS             complement(9725..10945)
                     /locus_tag="IXR05_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260460.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11092..12927
                     /gene="lepA"
                     /locus_tag="IXR05_001972"
     CDS             11092..12927
                     /gene="lepA"
                     /locus_tag="IXR05_001972"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAQ4260461.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(13021..14148)
                     /locus_tag="IXR05_001973"
     CDS             complement(13021..14148)
                     /locus_tag="IXR05_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4260462.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         4575 a         2602 c         2927 g         4057 t
ORIGIN      
        1 ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct agaaggagtg
       61 aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac tttgtccctg
      121 aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt gcattgatat
      181 taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag
      241 cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc cttgcaaatg
      301 gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg ggtatgggag
      361 gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta agcggacaag
      421 aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg ctgcaagaaa
      481 atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca
      541 ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg atgttcgggc
      601 catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga gagcttcaac
      661 aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac
      721 aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa tcagcggacg
      781 cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag aaggagaccc
      841 agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga tgacattaga
      901 cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc tgattgctaa
      961 acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac aagaaaaaat
     1021 gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga acatggatat
     1081 tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag tggagagtta
     1141 tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac ctgtggatca
     1201 tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag gtgattatac
     1261 cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg gtgcacaacc
     1321 agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg aggttatttt
     1381 gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc cttatgagga
     1441 acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt taggacgagt
     1501 aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa aagaagcgtt
     1561 ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat
     1621 tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga
     1681 tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa gcgctgggtt
     1741 gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat ttatcgagaa
     1801 atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt ctgaaacaaa
     1861 tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa tcttttgcca
     1921 cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa aacgactcca
     1981 tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga agagttaggc
     2041 ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt accaagcaat
     2101 gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc agattttaat
     2161 gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac gatcgtacta
     2221 gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa aaattatgaa
     2281 ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga caaatcaggg
     2341 attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat ccctcacggt
     2401 accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga taaattcgat
     2461 gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt aggtgagttg
     2521 cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa aaatgtacat
     2581 ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga ttttcataat
     2641 cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt cttccatttg
     2701 atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg cgatcatgat
     2761 cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga gttgaatcag
     2821 cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa catgaaagaa
     2881 atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat cgagcttggt
     2941 atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat ctcttacatg
     3001 ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg attcgaattt
     3061 gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc agaattgaac
     3121 acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc aatgatggaa
     3181 tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc cctctttttt
     3241 gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac aaaagttcag
     3301 ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc
     3361 cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg gaattagtca
     3421 agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac ggcacgattc
     3481 atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga ttacttccag
     3541 gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg
     3601 ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc aatgatgaag
     3661 tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg atcagtcaag
     3721 aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag ttattgctga
     3781 agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa ggaaaatccc
     3841 aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt gacgactcag
     3901 cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat attttccgat
     3961 ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc ggcattactt
     4021 atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg
     4081 atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa ggattaacag
     4141 tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa agttggaaga
     4201 agagtaatgg atgtattgtt acacaatctt ttgtggtttt accttttcat tgtgaatttt
     4261 tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg ctggcgtgtt
     4321 cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg attgatctct
     4381 cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt cgctgcaggt
     4441 gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga tgtcgtctaa
     4501 aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt ttgccattat
     4561 ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt ctaccagtgt
     4621 tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg aagggcgctc
     4681 aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg ggttcttgac
     4741 ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc tgatctcgga
     4801 gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg tgacagcact
     4861 ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct tggtcatcca
     4921 attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg ctggtatcct
     4981 tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga atgttcaaat
     5041 attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga aatgggtgga
     5101 tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta tccaagacag
     5161 gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt ggtatgtact
     5221 tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga ccatttcgtt
     5281 tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta ttggttcctt
     5341 tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg cagtttcttc
     5401 gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat ttgtgtatgt
     5461 gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa aagagaataa
     5521 agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca aagaaaaacg
     5581 ttatggataa gataatttta cgtttgtttg gctctttttt tatatacata caatcaattt
     5641 tgttttttta agatttatat aagtcgagaa aaaaagtcaa aaaactatgt gtatattttg
     5701 accaaaattg accaaagcga tataatagtt tttgtaaaga tcaaagaaat aagtgatctt
     5761 acctttaatt aggagggtat acctgtatga atattgagaa aatgactacg acgcttcaag
     5821 aagcgattgc tgaagctcaa cagattgcgg tcactcgaaa acatcaagat atcgacattg
     5881 cccatgtatg gaaaatcttt ttacaaccta atcattttgg tcgaaatttc tatacggatg
     5941 ccggattgga tgtcgaatct tttgaacatg aaattgatcg tctactggat gagtatccag
     6001 ttgtttctgg tggaaacgtc caatatggac aaaacctcag ccagaatttc tttcgattat
     6061 tgaatgaagc agaccaaata cgtgaaagct tcggcgacga gtttctttca acggaagtcg
     6121 ttattttagc gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg aataaaaacg
     6181 gattatctga aaaagaattg cgtaaaaaca tcgaagagat gagaggagga gaaagagtga
     6241 cctcacaaaa ccaagaagaa caatacaaag cattagaaaa atacggcgtt gatttagtac
     6301 agcaagtcaa aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa atccgtgatg
     6361 tcatccgtat tctttcacga aaaacaaaaa ataatcctgt tctgatagga gaacccggtg
     6421 tagggaaaac ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg
     6481 aaaatttaaa agataaaacg attttttcat tagatatggg tgcattgatc gctggagcaa
     6541 aattccgtgg tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg
     6601 atggacgtat cctcttgttc atcgatgaaa tccacaatat cgtaggggca ggaaaaacag
     6661 aaggaagtat ggatgccgga aatctgttga aaccaatgct tgctcgcggt gaattacatt
     6721 tgatcggtgc cacaacttta gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg
     6781 aacgtcgctt tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg atcagtattc
     6841 tgcgtggatt aaaagaacgt tttgagatcc accatggtgt taacatccat gacaacgcat
     6901 tagtagcagc agctacttta tctgaccgtt atattactga tcggttctta ccggacaaag
     6961 caatcgattt gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac tctatgccaa
     7021 cggaattaga tcaagttact agacgtttga tgcagttgga aatcgaagaa gctgcactga
     7081 aaaaagaatc agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg
     7141 aacttcgtga agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca
     7201 attctgtttc agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta gaagatgcag
     7261 aaaataacta tgatttagaa cgcgctgctg tattgcgtca tggtacgata cctcaattag
     7321 aaaaagaatt gaaggaatta gaagctaaag caaaagacag cgagattaag atggttcaag
     7381 agtccgttac cgaaaatgag attgctcaag tcgttggcag attaacgggt atccccgtaa
     7441 cgaaacttgt agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca cttcataaac
     7501 gagtgattgg tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt cgttcacggg
     7561 ctggattgca agacccaaat cgtcctctag gttctttcct tttcctagga ccaactggtg
     7621 tcggaaaaac cgaattagcg aaagcgttag ctgagaactt gtttgactca gaagatcata
     7681 tggtacggat cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag
     7741 ctcctccagg ctatgtaggt tacgaagaag gtggtcaatt aacggaagct gtcagacgaa
     7801 atccttatac aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata
     7861 tcttgttaca agtcctagat gacggacgct tgactgattc aaaagggcga gtagtagatt
     7921 tcaaaaatac ggttctgatc atgaccagca atatcggttc acagttactg ctggaaggcg
     7981 tgactgctga tggaacgatt ccagaagcag tggctgaaca agtcaacacg ctattacgtg
     8041 gaaacttcaa accagaattc ttgaaccgaa tcgacgacac gattttattt acaccattga
     8101 gcctagacaa cgtgaaagga atcgttgaca aaatggtggc gcaattggca caacgtctgg
     8161 aacatcaaga aatcctgctg acaatcagtg atgaagccaa aacgtggatt gctgaaaatg
     8221 cttatgaacc agcatatggt gcaagaccat tgaaacgatt tatcactaag gaagtagaaa
     8281 caccactagc taaagaaatc gttgcaggac atgttatgcc taaatcaaaa gtaacgatta
     8341 ctttacttga tggacaactt catttcaaaa cagaagagct agaagaaatc gtctaatctt
     8401 ccattgagac tataaaagaa aaaaggggtc tgacacaact agtgtcagac ctcctttttt
     8461 caaataaaca gtgttccaga agtagtttct tcgaaaaata agccgaaatt tcttgaagct
     8521 gcccgcttct gtcacaacct cttttattag gtatttttca ctttttctaa tttataactt
     8581 tcaaagtaac gctcatcttt tttactttga gaccatgcaa acaatcccat taaggcagca
     8641 cctatcgtat ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg tccgacaaac
     8701 agtgtgccat cagaagcagc aaaacgttga agattcatgc ctaagaactg gtcgcataag
     8761 aattcccaga actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc gaataagagg
     8821 aacaaccaag gactggtttt tgatatctca gcatctttca tcaagtaacc aatcaatcca
     8881 tagccaagag ctgtcaggac cattggactc accgcatgta agattttgtc ccaaaaagag
     8941 atgatactga tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag
     9001 taaaacaaaa cgattgctgc tggtatttta agtttgaaaa ctttcaaaat gacttgtggc
     9061 atgaaaatca atgcaatccc taataaagat tccacgataa atgtgattcc ttgagaagtc
     9121 gaatattttt gtgtgataaa ttcataaaaa ttatagcaga caacgaatac accaaaagca
     9181 agtaaagcta tttgcacctt tttgatttct ttaatcactg aaagtccctc catctaaaaa
     9241 tctttttact tctgaaagca actcaatttc tgaagaaacc acttttccgt tcaatttgat
     9301 caaacctatt gtatataagt tcaggtagtg aaattgattt tcagctgttt cttgtagtgc
     9361 agcgattttt ttcgggtggg ttccgccttg ctgtcgagta tcagtatata agccgatcac
     9421 tgggatgcct ttcgcataag ccacaccgat ttccgatgct accccggcat cgatcgtcag
     9481 cccatctagt aaagcaatca ttaaatcact agccaacact ttttctgtgt cagcaagagc
     9541 aatcattcga ctgtctgcat aagcagtttt gtcattgatt gcttcatttt cttgaggaag
     9601 atagatcgaa agctcagaag agagctctct gatttcttta actaactgtt ggttatataa
     9661 caaatcactt ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa catcatcctt
     9721 tttatcaaaa ataatcgcta aagtaagctt ccatgtttgg aatgatacgc tctagtgact
     9781 tcagtgtttc ttcatctgtt tctaaccgtt cgattcttgc caaataagaa gcacggcgat
     9841 aattcatcat caagcaagtc aatgtttgga tatccagtcg aacggatttt cctataggtt
     9901 catttaagac acggacttgt ccctgttcat cccatgttaa agcgaagaca ccattattcc
     9961 aaggagcgac aggatcttca atgatgaaat gaaaagcatc agctgttcca acaaacggaa
    10021 accgttgaag gaattctttt acatcaacga tccgagccat aaaatatggt tcgatctgct
    10081 ctttgatctg actatcttca atcaaaaatg ctaaaggctc atttttataa atatctccat
    10141 gtacccagta gatcatggaa aaatgtgcgg aaataaagtt ccataagcca tttcgagctt
    10201 cttgatcaag atagaacatt tcttttacgt gaaatatttc ttcagctacc caatagaaca
    10261 gaacacctct tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat
    10321 tttcgaaacg ccaatactct tcccaatgaa aatcactgcg gaataaagca ccatggtttt
    10381 gttgggcaaa tttgtcataa acggaaaata cgtctggatg atcaactggt aatcgctcaa
    10441 ccataccact tactgggatt tgtttaggta gctgtgtatc tctgatttta aaggaaagtt
    10501 tatcagacat gatttcccat cctttacgcc gatagtaggg gatactgtaa ggatacaaat
    10561 aagagatcca ttgcttattc ttgcgcatat tatccaatgc aacgataatt agatcttgca
    10621 tcaatccatg gttagcatat tctggataag ttccaactcc agtcacacca cccattttat
    10681 aacgtgcacc gtgaatattg acttcacaag gatagatagc gatttgagag atcagtttat
    10741 tttcgtggaa ccatccgaac actttcgata cttccaaaat cggttttttg gaacggataa
    10801 aagctcgttt attctcaaac ccgctttcct cgatgtctgc ttcagtcact tggaacacat
    10861 aggaaagcaa ttcattgaat tgatcgatat gttcttgagt gaccggtttt aattcaagat
    10921 tttctctaaa atctttttga tccatttttt catctccatt tattagcttg ataacagtat
    10981 agcaaaattc tacaaaaaaa acttctatag ctgactaatt aaaaactctt taaattactg
    11041 cttttcgttg gtataatgga aagtgctgat tatatgaaaa gaggagacgc tatggatata
    11101 aagaaaatga aagaacgcca agagcagatt cgtaattttt cgatcatcgc tcatatcgac
    11161 catgggaaat ctacattggc cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc
    11221 gaaatgcaag atcagctgtt agactcgatg gatttggaac gtgaacgtgg aatcacgatt
    11281 aaattaaatg ctgtagaact caattacaca gcgaaaaatg gagaaacata tatctttcac
    11341 ttgattgaca ccccagggca cgtcgacttc acctatgaag tctctcgaag ccttgctgcc
    11401 tgtgagggtg ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc
    11461 aatgtttatt tagcgttaga caatgatttg gagatcctgc cagtcatcaa taaaatcgac
    11521 ctacccgcag cagatcccga acgtgtccgt caagaaatcg aagacgtaat cggaatcgat
    11581 gctagtgaag ctgtattagc cagtgccaaa tcagggattg ggattgaaga tattctcgag
    11641 cagatcgtgg aatatgttcc tgcaccaagt ggagacttag atgcaccgct aaaagctttg
    11701 atctttgact ctatttatga tagttaccgc ggtgttgttc taaatgtccg gatcacggac
    11761 ggtatggtca aacccggaga caaaatcaaa ctgatgagta atggcaaaac atttgatgtt
    11821 acagaggtcg gggtcttctc gccaaaagca gttgctagag actttttgat ggtcggtgat
    11881 gtcggttata tcacagcaag tatcaaaact gtccaagata cacgagtagg ggatacagta
    11941 acgttagcag acaatcctgc cgctgaagct ttaccaggtt accgaaaaat gaatccgatg
    12001 gtttattgtg gtctttatcc aattgatact tctcgttaca acgatttgcg ggaagcttta
    12061 gaaaaactgc aattgaatga tgctgcttta caattcgaac cagaaacctc tcaagcatta
    12121 ggttttgggt tccgctgtgg attcctcgga cttcttcata tggatgtcgt ccaagaacgc
    12181 ttggaacggg aattcaatct agaattgatc acgactgcac catccgttat ttaccatgtt
    12241 aataaaacgg atggtacgac tgctacagta gataacccgg cagattttcc tgaacctgta
    12301 acgattcagg atgtagaaga accattcgtc aaagcacaga tcatggtccc aaatgatttt
    12361 gtcggtgcag taatggaact ttctcaacga aaacggggag aattcattac gatggattat
    12421 ttagatgatt accgagtaaa tgtcgtctat aatattccgc tttctgaaat tgtctttgac
    12481 tttttcgaca aattgaaatc aagcacgaaa ggctatgcct cattggatta tgaaatgtct
    12541 ggttatcaaa aaagcaagtt agtgaagatg gacatcttgc tgaatggaga aaaagtcgat
    12601 gcattaagct ttatcgttca ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa
    12661 aaactgaaaa aactaatccc acgccaacaa tttgaggtgc caatccaagc agctattgga
    12721 caaaaaatcg ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt
    12781 tatggtggag atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga agggaagaag
    12841 cggatgaaac aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa
    12901 atggacgagg acgaaccgaa gaaatagcaa gggtttgttt gaaaacagtg taaaaaataa
    12961 accatgttta catggatttg ccaccggttt gccaccggtg gtttttttcg gtggcaaaaa
    13021 tcaagaattc tttctaagat tttccatgat atcgaccgtt tcatttctca tcttatctgt
    13081 tacatgcgag taagtatcca tcgtaattga aattctgctg tggcccaatc gttcagagat
    13141 ttctttcatt tttgcgccat tttcgagaag aagtgtagca tgagtatgtc tgagagaatg
    13201 gaagttaaaa gagagggaga gtgcattcga tatcctccta gtattccatt tcactacact
    13261 tggcgtaact agctcaccgt cttccttcgt acatactgca tttgaatcaa tgtagagctt
    13321 tccatacttc attcgatttt ctaattgttg tttcttatgt tttttcagaa ttgctagcaa
    13381 ggtttgtcca ataaaaatcg ttcgattgga actgcttgtc tttggcgtac catataccca
    13441 tgcgccgtca ttctttacca tttgtttctc tacagtaatt gttccatttg aaaaatcgac
    13501 atcatcccac gtcagaccac aaacttcgcc aacgcgcatt cccgtataaa atccaatatt
    13561 caaaggaata tagaaaggat gtccttcagg agtaatttct agcatatgat caaagtcctc
    13621 aagagaaatg atttttagat cttttttagt cgttggtcgt gcttcatatt ttggtatttt
    13681 tacatacagc ataggatttt gcttgattaa tccccaagga taaaccgcca tattcagcgc
    13741 attcttaagg acagagtgag taatagtcat tgttttcttc gagtaaccct ttttaaattc
    13801 agcattgatg aaattttgta aaagagcagg ggagagatcc gtaagttttt tctttcctaa
    13861 ataaccgttt atatgatttt tgatggtaaa tcggtagttt tcataggtat tgtattttag
    13921 atttagttta acgtattcct ccatccaaaa atcaaggtat tgttttactc gagtatccgt
    13981 acctaaaaag tattgtcctg tttcgtcaat atctgataaa acttttcgta aagcagcttc
    14041 ggcctctggt cgggtgtctc cgccaacttt ctccactttt tttcttgagc catcatcatt
    14101 gatatcttcg ccgtttgtat aattaagcga gacaaataaa aaagccattt atgttacact
    14161 c
//
LOCUS       DACGDM010000063        13948 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.065, whole genome shotgun sequence.
ACCESSION   DACGDM010000063 DACGDM010000000
VERSION     DACGDM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.065"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(221..1423)
                     /locus_tag="IXR05_001974"
     CDS             complement(221..1423)
                     /locus_tag="IXR05_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4260463.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1426..1620)
                     /locus_tag="IXR05_001975"
     CDS             complement(1426..1620)
                     /locus_tag="IXR05_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4260464.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1667..2515)
                     /locus_tag="IXR05_001976"
     CDS             complement(1667..2515)
                     /locus_tag="IXR05_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HAQ4260465.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2720..3070)
                     /locus_tag="IXR05_001977"
     CDS             complement(2720..3070)
                     /locus_tag="IXR05_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260466.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3665..4111
                     /locus_tag="IXR05_001978"
     CDS             3665..4111
                     /locus_tag="IXR05_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAQ4260467.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4735..5727
                     /locus_tag="IXR05_001979"
     CDS             4735..5727
                     /locus_tag="IXR05_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4260468.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5743..6627
                     /locus_tag="IXR05_001980"
     CDS             5743..6627
                     /locus_tag="IXR05_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4260469.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6676..8283
                     /locus_tag="IXR05_001981"
     CDS             6676..8283
                     /locus_tag="IXR05_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4260470.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8284..9768
                     /locus_tag="IXR05_001982"
     CDS             8284..9768
                     /locus_tag="IXR05_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAQ4260471.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9945..10937
                     /locus_tag="IXR05_001983"
     CDS             9945..10937
                     /locus_tag="IXR05_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4260472.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10989..11858
                     /locus_tag="IXR05_001984"
     CDS             10989..11858
                     /locus_tag="IXR05_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4260473.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12278..13843)
                     /gene="guaA"
                     /locus_tag="IXR05_001985"
     CDS             complement(12278..13843)
                     /gene="guaA"
                     /locus_tag="IXR05_001985"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAQ4260474.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
BASE COUNT         4266 a         2363 c         2882 g         4437 t
ORIGIN      
        1 acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag taaggtactg
       61 ttctatgggg cgcttacgtt gaaaaacgtt gatttatcgg cattccccat ccatattata
      121 tttacgtctt attcccactc aatatgagta gcctcgtaaa gaagctatta tatcagtgct
      181 ttttcagcct attcctcatt ttggtaggga aatggtaggg ttagattttt actgcttgat
      241 ttccattaaa gtttgcaact ttagattttg ttgcacaggt aaatttaatg tttcctgtca
      301 tttgttctgc aattccttca tcattacggc tccatagatg agcgtagtgc tttaaagtga
      361 tttcagggct agaatggcct aaccgttgcg acacgaccag aatgtctgcg ttaaactcat
      421 tgattaggta gctaacatga gaatgacgta atccttttcc ttgtattagg ggtaccttag
      481 ctagtttggc ataacgctga ataattcgtt gaacagttga acgatagagt gggaggtcag
      541 tgtagctaag aataaattgt tctacaccat gatttttttg aataactttc cactttttta
      601 gcacttcaat tgtatcatcg tccagagaaa tgatccgcaa gccgctttca gtttttgtgt
      661 aaggtttccg aataaaatct ttttgatttg tcatttccaa ggtgtgatga accctcaact
      721 ttttacgttt gaagtccacg tcattccaat taagtgctaa tccttcgctt acacgaacac
      781 cagtcatgta atatagccag atcattaaaa aacacatatg ttcgtagaaa tcatctttat
      841 aaatttttgc caaaacttct tcaaattctt cttttgtcca gtaaggaacg attgattttc
      901 cttttggaat tgcttttgtt cttttggaaa tattctcatt cagaaattgc agggtgaccg
      961 catagtctaa tgatttacga aacataccgt acataagtga actgtatgct tgtgagtatc
     1021 cgctatcgtt caataaccaa attcgataat tttcacaatc tcgcacattg atttcacgaa
     1081 gcttcttatc accgaaaaat tcagtaatct gaatcaatcc acactcacga gaactccaag
     1141 tacttttttg tacgctagct ttgtagtgtg gaacgtaaga ctgctccata aattctttgt
     1201 aagttaaatc ataattcgca aatccattta caaccatgta ttcatttttt atacgcatga
     1261 cttctttgtg tgcttcacga gctgatgaga atcgttttcc tagagaatct tttgttcctt
     1321 tcttctggat cctctttcca gtcacttgat ctgttcctaa ctcaactaga taagaaaagc
     1381 gaccattttt atcttgatac acacaagggt attttgtttt catagttatt cctcctgtga
     1441 aagaggaaca cctataattt cttcaattac ttgtcggggt actaccccaa ctcttttatt
     1501 attataatat ggatatccct gatttaccat tcttgttttt gcttgtcgga ttattgtggt
     1561 agcttgatgt gttttaaatc ctagagcctc taaatctttt cgacaaattg tatttttcat
     1621 tgtataaact cactttcaaa gaaaacacta tcattgggta atagtgttat ttctttattt
     1681 ttgtataatg aacggtactt tcttgaaaat ccatcacttg ttcaggactt cccaactcat
     1741 ttaaagctaa agcattgtaa aaaaatggac gtctaactat atattcgctt gtatatagta
     1801 tatcttgatt cgtggaatca tagggtttct ttaccatctt tttggtgaca gttggtagtt
     1861 tgagattccg ggacttgaaa aaagcttttt tcttatgctc tttcaattcc agctctttat
     1921 cgaaatattt gctgatatag cgcccgcgat tttcgatact gtctacatcg atcttgttga
     1981 tcttaacgaa accctgaccc caaatcgtag ttaaccggtt aaatgagata aaggggaaat
     2041 caaacaagat aatatggtag tggattgcac cgcgttgctg cttttcccac gtggcgagat
     2101 actttaaatt tgctttttta gttttataga ggtcataatt cagtcgtttg ataaattttt
     2161 taaattcatt atttgcatac tcaatgtctt gaatgttttc tttgaaagtg agagttaaaa
     2221 atttcgtttg attgtcaaaa ttcgtgtcta caaggcgggc aatctcaaat cgcatacttt
     2281 gataatgttt ctgtttgcgt tttaaactgt catattgtcc ttgagcggat aattcatcat
     2341 agttttttct tttttcaaga gtaatatcat tttcataaat ccaagctaat ttttgttttc
     2401 gttccagatt tacttcgttt tcgatcgttt tacgtttggg agtaatgatt gcttcataat
     2461 cataaatttc aatatacgtg ggagtttcaa tgattttctg attataagct tgcaaaaatc
     2521 atcactcctt gttgcgtatt cgattgtcaa agaaccagtc attttctcct gatgttgatc
     2581 tataaatcaa gttaaggggg aaggcctgcg tagcagccct tctagcctat ggggtgttgg
     2641 gcggtcttaa cggacagaaa cggctctgtg ggcgctgccc cgccgtttcg tcctaaccac
     2701 ccaacactcc atagtatagt tagttttgtg tagtggtacc ttgttttctg ggaatcaaag
     2761 ttgccgtatc agcggttgcc gataacccat aactgacaaa ttgtccattc gagcgtcccc
     2821 aaggtacaat caccaaattg gtaaatgtaa ttatggctaa accttgttgg gtaagttctt
     2881 ccggcgtgat cacaggatgt tcagatttga ctttgacact gattttttcg tagcgaagtt
     2941 ttggtaggat acattcgtag ctccaaccta gaatttcgcc ctccttttgc cagcgagtga
     3001 cattgacgac ttggtattct ttttcgagtg tttcttttgg taaactgaga tcggtaattt
     3061 ttattggcat cacaattctc cttttttata cgaaagttta tacgatttga ttaaaaaata
     3121 tagatggcca tctacgactt gtattatata cgagaactta tacgtagtca agagattttc
     3181 taaaaaaata tatacgattt tttatacgag tgttataatg aaaaaaatga taaggaggaa
     3241 tttgaatatg tttggtttag tacaacctaa taaagtgaag gtgggccaac gaatcaaaga
     3301 aataaaagac ggaatgtctc tctcttttac agaattaggg aatcgattag gtttaaaaaa
     3361 gccgacgatc agttcctacg ttcaaggcta tgcgttggct cctaagagtg tgatcaacca
     3421 attatctagt atcagcggaa aacctgtcgg ctggttttat tttgggcatg tggaagaata
     3481 tatccgagag tatttgtttc tcattggtca gaaaaaaata gtggacgatt atcctgaaat
     3541 cattgagaaa ataaagcaag aattttatac gggcgagttc aaaaatcctg cttgggagaa
     3601 tgagctaggc tatcctttgg aggaatttat ccaagaatgt tttgtagaat attcgagtga
     3661 aatcatgaag gactatgtcg tacagattac gaaagaggta cttgaagaat ccaaaacgct
     3721 aaacaaacta tcatcaaaag caaaagaaga agctgtcacg attctttcat ctgggatcat
     3781 tgactatatc gagatgagtg gtgagatcaa gtatggagag aaagatcgca ttgcgaaaat
     3841 ggtgaaagaa tcaataaaaa cctttgatgt gaaacaagac ctgacattta atgattccta
     3901 tttgattgga aagttgatca atattcttgg tacagatgaa gatacggagc tgtttctttc
     3961 ttctttatca atgatattta ctgataagca tttttccact cgatttggtg gggaagaatt
     4021 agtcgaaata tttcaatcga tgcgaccagc gttaatcaaa ctctatcggg agaaaacacc
     4081 agatgaattt tatgattggt ttgagaagta aaataagaaa agtggcttag attacaagtt
     4141 ggtgaaaaaa tttttttcag cataacatca gtaatctata aaggggttgt tgattatact
     4201 gtagaagtta agtactcaag agattttttg tacgtaaaca aagcaaaaaa gggtgcagtt
     4261 tcactagaaa atgtactctt ttttgtgatt tttcttagtt atagagtttt tttgaaactt
     4321 taaaaatgag aaaacatatt gattttaaag agtgtagaca tagcttcttt tgctaaatag
     4381 attaaactta ctggtgagtg gtcttgaaca tacttttaaa tcacatttta ctgagtttta
     4441 ttggatttta taattcattg gaaacctcgt acttaatctg tttttatcta tcgactagaa
     4501 tctgtatata ttccagctat caatgaggcc gcagaaaagg gtgcttaaaa ataatctgtt
     4561 gtttaaaata ttattatcag aatacttaga tacaaaattc tggcacaaag taaaaaaaat
     4621 attgacttaa aaaaatggat atggtaatct ataaacgaaa atagtggtaa cgtttccaaa
     4681 atgcatcttc gttaaatttt tattttttta aacgaaaatg gaaacgtttc taaaatgtat
     4741 tgggaggaga ttgaattgga aaagacattg ggaccaggtg gtgagataag ggcggtacaa
     4801 cgggataaaa aaaatatttc gaagtgggaa aaattaaaga aacagttgcg gcgtgataag
     4861 tggatgtact tgttgctctt accaggtatc atcatgacgt ttatctttaa gtatgtgcca
     4921 atgtacggtg ctgtgattgc atttaaagac tataatccta tgctaggaat tttggaaagt
     4981 ccttgggtag gactagatca ctttagggaa tttatcagtt caccaaattt tacgcttttg
     5041 ctgagcaaca cattaaaaat tagtatttat ggtttattgt taggtttttt tccaccaatt
     5101 attttagcac tgagcttgaa tcaaattatc aataaaaaaa taaaacagaa aatccagttg
     5161 attctatatg cgccgaattt tatctcagta gttattattg tggggatgct gtttttgttc
     5221 ctatccgcaa atggacctat taatgggtta gtagaaaagg ttacggggca accaattatg
     5281 ttcatgtcta atccagctta tttcagaacg atttatattt tatcgggaat ttggcaagga
     5341 atcggctggt catccattct ttacaccgca acgctggcgg gagtcagtac cgatttatat
     5401 gaggcagcaa atatcgatgg ggcaaatatt ttacaaaaga tttggcatat cgatttgcct
     5461 gcattgaggc ctgtgatggt gatcagcttc atcttggccg ccggcggtat tatgaatgta
     5521 ggatatgaaa aagcctactt gatgcaaact tcaatgaaca tccctgcctc agaaatcatt
     5581 tccacttatg tatacaaagt cggcttgcaa tcaggtgatt atgcctactc tgctgctgtt
     5641 ggtctgttca atatgattat taatgtcgtt ttattactga ttgtcaacaa tataaccaag
     5701 cggctaaacg atggtcaagg cttgtaatga aaggagaaaa ttatgaatag tgctttatca
     5761 aaaatcgacc gtcaaatctt atggttgaat cgagtgattg taactttttt agtcgtcatc
     5821 accattgttc cgctgattta tgtactggta gcttctttta tggacccagc tactttgatc
     5881 aataaaggta taagcttcaa tccgaaagat tggacaatac agggatatca acgggtattt
     5941 gcagatgatt ccattttacg cggttttgta aattcgttgt tttactcttt tagcttcagc
     6001 ttattgactg tatttattac gatgatcact gcgtatcctt tgtctcgacc taacttggcg
     6061 gggaaaaaga ttattatgac tttttttgtc attacaatgt tcgtgggtgg tggcttgata
     6121 cctacctatt tattggtaaa gaacttgggc atgttagata gtgtatgggc gattatcgta
     6181 ccaggtgcta taaatgtgtg gaatattatc ttagcccgta cctattttag tgctttgcca
     6241 aaagaacttt ctgaagctgc tactatcgat ggcgccaatg acttgcaaat actgttcaaa
     6301 gtcatgcttc cattagcgaa accaattatg ttcgtattgt ttttatatgc ctttgttggg
     6361 caatggaact catactttga tgccatgatt tacatcaaag atcccgactt acagccgttg
     6421 caactcgtat taagaaatat tttgatccaa aaccaacctt cacaagacat ggtgggagcc
     6481 aatactgcca tggcagaaat gaaacaaatt gctgagttga tcaaatacgc aacgatcgtc
     6541 atttctagtc tgccattaat cataatgtat cctttcttcc aaaaatattt tgataaaggt
     6601 gttttagttg gttctgttaa agggtaagta ttgttcacta tttgtatgaa taaaaattat
     6661 aaaggagatt ttaagatgaa agcaaaatgg atgctgccaa tcgtttttac ttccgtacta
     6721 attttggggg cttgtggagg ctcaaaagaa aagagtaaat caagccctga ttatgaacta
     6781 gaaaatgtct cttttccatt gaaagaaaaa gtatctttaa aaatgatgtc tcaaagtgcc
     6841 cctttggctc ccaatgatcc taatgacaaa ttgattttcc aacgattaga agaagagacc
     6901 aatctccata ttgattggac aaactacagt agtgattttg ccgaaaaaag aaatttggat
     6961 atcgctagtg gtgatttacc agatgccatc ttcaacgccg ctgcaggtga ctatgattta
     7021 ttaaactggg cggaaagtgg cgttattgta ccgattgaag atttgatcga agattatatg
     7081 ccaaatctga agaaaatttt tgatgaaaac cccgaatacc gacaaatgtc tactgcacct
     7141 gatggtcaca tttactctat gccttggatt gaagaattag gcgaaggaaa agagtcgatt
     7201 catacagtaa atgggatggc ttggatcaac aaggagtggt tggataattt gggtcttgaa
     7261 atgccgcaaa ccactgatca gttgatgact gtgttggagg ctttcaagac gcaagatcca
     7321 aatggtaatg gtgaagcaga tgaaattcct tttagcttta ttaacaatgg aggaaacgaa
     7381 gacttaaaat ttttaatggg ggcattcggt ctaggtgata atgatgacca cttagtcgtt
     7441 gataacgatg gtcaggtaca atttactgct aacaaagaag ggtataaaga agccatcaaa
     7501 tatttcaatg aaatgaataa taaaggtctt attgataaag aggctttcga acaagattgg
     7561 aatacgtatg ttgccaaagg gaaagaacat aagtatggcg tgtactttac ttgggataaa
     7621 gcaaatatca cgggtgcaga tgatagttat gacgtcttgc cagtcttagc gggaccagat
     7681 ggaacgaaac atgttactcg tacgaatggc atgggtttct caagagatcg tttcgtaatt
     7741 actagtgcga ataaaaactt ggaacttaca gctaggtgga tagataaaat gtatgaaccg
     7801 ttacagtctg tccaaaataa ctggggaacc tacggtgatg aagcacaggc gaatattttt
     7861 gaattaaagg atggtatgtt aaaacatttg cctttagagg ggacagcacc gggggaacta
     7921 agacaaaaaa ccgaagctgg aggaccatta gcagttcttg attcttatta cggcacagtc
     7981 actactatgc cagatgatgc gaagtggcgt ttagatttga tgcatgacac gtatttgcca
     8041 tatattacag aagacaatat ctatccacgt gtctttttag aaaaagaaga aacagatcga
     8101 ttagcaaaaa tcgaaacgga tatgtgggat tacatctatc gcaaaagagc agagtggatc
     8161 accggcggta aaatcgatga agaatgggaa gaataccttg ctgaattgga acgtgtaggt
     8221 ttggaagaat ggattcaaat aaaacaaact ggctatgata attttttgaa gggagcacaa
     8281 taagtgttag tagaagaaac ggcgattttg gataaagcaa atcgatttat tgaaatgatg
     8341 cgaggaaaag ttaaccctca gtatcgacaa aactatcatt tttccgcacc catcgggtgg
     8401 ataaatgacc ccaatgggtt tatatattac aaagggcatt accatctctt ctatcaatac
     8461 tatccttacg atagtcgatg ggggcccatg cattgggggc atgcgcgcag tagtgatttg
     8521 gtccattggg aagatctacc agtagcgtta gccccagatc aaccttatga cagcggcggg
     8581 tgtttctcag gaagtgcaat tgaaagagac ggaaaactat atttatttta tacaggctgt
     8641 caagaaattg atggtattag ccatcagcat caatgtttgg cggtctctga agatggtatt
     8701 cattttagca aatacagtgg taatcctgtg gtagcagaaa aacagctagg tgaaaatggg
     8761 ctaatacaag aatttcgtga tcctaaagta attgttcaca acgatggtta ctatatggta
     8821 gtagctacta aatctacaca gtctactggt agaatagtga tgtttcaatc gtcagatttg
     8881 tatacttggc acttttactc tgtgctgcta gaagggactt cagagcaagg aataatgtgg
     8941 gaatgtcctg atttattcca tttagacgga cgagatgtct taatcatgtc tccgatacaa
     9001 atcaagaaga acggactgga atatcataat atcagttcta ccatggcttg tattggtgag
     9061 gtaaactggg aaacaggtca gatgatagtt gataatttcc atgaaatgga ttttggaatg
     9121 gatttttatg caccacaaac aacaagagat cctaatggtg gacgggtgat gattgcttgg
     9181 atgcagatgt gggatcgtac attgcctaca catgagttag gccatctttg ggcaggctct
     9241 atgagtttgc cccgagagtt aagagtgaaa aaaaatcgat tggtacaaaa acccatctca
     9301 actgtatata gtcatttagt ttatcaacaa ggcagtgaaa atattgcagt gactgacaca
     9361 tcagtcgtat ttcgaaacgc gctgtctgat tcttcatatt tacatctagt cgcagatttg
     9421 gagaaagctg aagtttttac aattgaatta ctgcggtcta agacggattg tctcaaacta
     9481 gcctatgaca ctgctacaca ggtttttgaa ttggatcgtc agaaactagg aagagagctt
     9541 acaggggcgg aagaagaccc tctgaatgta cgaaaagttg aagtaccttt gattgataat
     9601 cagctcgttc ttgagatttt tagagatacc tcatcaattg aagtctttat taatgggtta
     9661 gaagttatga cggctacttt ctatgagctg gaaaaagctc gagatatctt gtttcattcg
     9721 atcggagaaa gtcgtattca agcttttgaa acagcgagtg tgaaataaat gtttgattgc
     9781 ttaggcgatg aatcaattat ttaataggtt ttgaaggata atgtttttag aaaagaacag
     9841 atagctagat ttcccatgga tttgctatta gtattttgaa aaaattagta atttatgaca
     9901 aaattcatta tactaaactt gtgcagaaat gtgagggatc aactatgaaa gcaacaatga
     9961 aagatgtcgc aaaattagca ggtgttggag taggaactgt ttcccgggta ttgaataacg
    10021 gttctgttaa agcttctact agagaaaaag ttgaagcagc aatgacagag ttaaactatc
    10081 aaccagattt ttatgcccgg gggttaaaga tgaagcatac gaacacggtt gctttgattc
    10141 tacccacggt atggcatcca ttttttggcg aatttgccta ccatgtagaa acagcattag
    10201 aaagacaaaa ctacaagctt tatttgtgta actccagtgg taatagtgaa aaagaacaag
    10261 aatatatcca gatggtcagc caaaataaag tagacggcat cattggaatt acttattcag
    10321 atatcgatga atacatttcg agtaatctgc cttttgttag tattgaccgt tatttcactg
    10381 aagaggtgat ttatgtgacc gctgacaatg cggccggtgg acgtttggct gcaaatgaac
    10441 tttatcgccg aggatgtcag aatgtagcat atatcggtgg gtaccaagaa acaccgaatg
    10501 aaacgaagag tcgtcgaaaa tattttgaaa tcgagtgccg tcaactgggg atttcctata
    10561 aagcgttaga tatgttagaa cctttagacc atctctcaga acgtgtaaca aattttttgt
    10621 tagagaatcc cgatatcgat gggattttta cgatcaacga tccaatggca ttagctgtca
    10681 ttgatatgct tgaaaaaata gggaaaaacg taccagagga tgtccaagtt atcggatttg
    10741 atggtcaaaa gatgacagaa ggagatcctt atctagtctc aacgattgcc caacctacaa
    10801 agcaaatggc ggaagtggca gtggcaaaat taattgctgt cattaatgga gagacagtag
    10861 aaaaacgtac cgtattgccg attgaatttg gcgaaggtga cacaacgaaa cctttagtga
    10921 gaaacgattt tgcttagtgc aaatacgttt ctttttttga aaatgagtga atgaaaggtg
    10981 tagataaaat gttatatggt ggaatagaag ccggtggaac aaagtttgtc tgtgggattg
    11041 gtaatgaaca attacaagtg atagaacgga aaagttttcc taccacaaca ccagaagaaa
    11101 cgatggagca agtgtttgat ttctttgata agtacaaagg aaatatcgca tcaattggtg
    11161 taggagcatt tgggcctatt gatattcaaa tcgaatcaag aacttacgga tatatcacca
    11221 acacaccgaa gttagcttgg caaaattatc attttgtagg agctttggaa aacgccttgt
    11281 cggttcccat ctattggact accgatgtaa atgctgcttg ttatggagaa tatatggcag
    11341 ggtatggaaa aggtaaaaat agtgttctgt attacaccgt tggtacaggt gttggtggtg
    11401 gtgctgtagt ggatgggaaa atagtcgcag gttttagtca tcctgaaatg ggacatatgc
    11461 tcttacaacg tcataatgaa gatcaatttg aaggaatctg tccttttcat catgattgtt
    11521 tggaagggtt agcatcagga cctgcgattg aaaaacgctt tggaagaaaa gcccagacta
    11581 tctcatttga tcatccttat tggacgattg aggcagatta tcttgctcag tgtgtgtata
    11641 acacaacgtt actatatgca ccggaagtaa taattttagg cgggggtgta atgaaacagc
    11701 cgcaactact cgagttgatt cgccaatcgt ttaaagaaaa aatgggttcc tacgtggata
    11761 cgcctactct cgaagaatat ctactaactc caaggcttgc tgacaatgcg ggcttgattg
    11821 gctgcctagc tttagcaata aagaaactca atcattagaa tagtatttat tagaactatt
    11881 cataacatac cggaagttta aaagggtatt ctgaaactta aatagtctca attcattctt
    11941 ctttcttgag aatctgagta gagactttta ttctgtttca aattaatata attacgaaat
    12001 gatattgagt acaagaaagt tctttttacc agatctttta aatcgaaaaa tctgatatat
    12061 atatttatag tactaaaaat ctgattagat aaaaagctaa ttcaatagga aaataaaggt
    12121 agtgaataaa agcaaagccc ttgttagtag ttaatctaac aagggctttg gtagggaaaa
    12181 tggtaggaaa ccatcttatt ttttacgaaa atcaggaact ttagtaattg aataatgttg
    12241 atttataggt attcctcatc catattatgt tggctcttta ttcccactcc actgttgcag
    12301 gtggtttgct ggtaatatca tacacgatac ggttaacgtg tgcgacttca tttacgatac
    12361 ggacactgat tttttgcaag acttcccaag ggatacgggc aaagtcagcg gtcatgccgt
    12421 caatagaagt gacagcacgg atacctacag tgtagtcata cgtacggcca tctcccataa
    12481 ccccaacaga gcgaatgcct ggtaggacgg tgaagtattg ccagatgtcg cgatctaaac
    12541 cggcattggc gatttcttcg cgcaagatag cgtctgattc acggacgatt tctaattttt
    12601 cttctgtcaa ttcaccaagg acacgaatac ctaagcctgg tccagggaat ggttggcgcc
    12661 aaacgatgct gtcaggcatg cctaattggg tacctaattc acgtacttcg tctttgaaca
    12721 atgtgttcaa tggctcgatc agcttgaatt gcatgtcttc aggtaatcca cctacattgt
    12781 gatgtgattt gatggtttgg gcagtttcag ttcctgattc gatcacatcg gtataaaggg
    12841 ttccttgtgc aaggaaagaa acgccttctt caccggcaag tttggttgct tcatcatcga
    12901 agacatatac aaattcattt ccaatgattt tacgtttttc ttctggatca gacacgccag
    12961 caagttttga taagaaacgt tctttggcat cgacttttat aatgttcaag ccaaattttc
    13021 cgccaagact ttccataact tgttctgctt cacctttacg caacaatacg tgatcaacga
    13081 agatacatgt taattgatcg ccgatcgctt tttgtaaaag aacaccaaca acagaggaat
    13141 ctactccgcc tgaaaggcct aataaaactt ttttgtcacc gacttgttca cgaatttttg
    13201 cgatctccat gtcgatgaag ttatccattg tccagtcacc agtacattgg cagacatcta
    13261 gtgtaaaatg gcgcaacaag tcatttccat attcggaatg gcgaacttct gcatggaatt
    13321 ggattccgta cattttgcgt tctgcatttt ggatcgatgc gatggggcaa tctttgctgg
    13381 tagcaacgac atcgaaatca gtcggtgctt gggtaactag gtcaccatga ctcatccaaa
    13441 cggtttgttt ttcaggagtg ttttggaaaa gggccgcttc tgcagaagtg atttccaatt
    13501 ctgcttttcc gtattcacgg tttttggctg gtttaacttt tccgcctaat ttataagtaa
    13561 tcaactgcat accgtaacag attcctaaaa ctgggatccc caaatcaaaa atcttttcat
    13621 caataccaaa ggccttctca tcataaacac tgtttggtcc gccagaaagg atgattcctt
    13681 tagggttcat tgcctttact tcttctgcgg taatgcggtg gctcatcaac tctgagaaaa
    13741 caccgaactc acgaatacgg cgagtgatca gttggttata ctgactaccg taatcaagta
    13801 cgataatttt tggctcttcg tcaaatcgtg ttggtgaaga caaatttgaa taaaacttag
    13861 tccgatatgc ggcgcgttct gtgcgccgca tattttttta gttttcaaag atcagacctt
    13921 gttgtaaata gatccgtgcc cgaaagtt
//
LOCUS       DACGDM010000064        13918 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.066, whole genome shotgun sequence.
ACCESSION   DACGDM010000064 DACGDM010000000
VERSION     DACGDM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.066"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            131..505
                     /locus_tag="IXR05_001986"
     CDS             131..505
                     /locus_tag="IXR05_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4260475.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="IXR05_001987"
     CDS             complement(619..1248)
                     /locus_tag="IXR05_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4260476.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="IXR05_001988"
     tRNA            complement(1382..1454)
                     /locus_tag="IXR05_001988"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="IXR05_001989"
     tRNA            1668..1741
                     /locus_tag="IXR05_001989"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            1696..1845
                     /locus_tag="IXR05_001990"
     CDS             1696..1845
                     /locus_tag="IXR05_001990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260477.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2338..3666
                     /locus_tag="IXR05_001991"
     CDS             2338..3666
                     /locus_tag="IXR05_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4260478.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="IXR05_001992"
     CDS             3868..4701
                     /locus_tag="IXR05_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAQ4260479.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="IXR05_001993"
     CDS             4717..5454
                     /locus_tag="IXR05_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAQ4260480.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6535)
                     /locus_tag="IXR05_001994"
     CDS             complement(5609..6535)
                     /locus_tag="IXR05_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAQ4260481.1"
                     /translation="MKENMLTGGVSPDVANPLLDAEITIPKHVELLVEDIFNLPSPHI
                     MPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIGNKLPIVLTGAMRSS
                     NELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTKTHTTNVATFRTPTL
                     GPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGDLLEAIAHTKVDGLV
                     IEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDYEGGGKELEKMGIIF
                     CNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="IXR05_001995"
     CDS             6810..7643
                     /locus_tag="IXR05_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAQ4260482.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="IXR05_001996"
     CDS             7677..8516
                     /locus_tag="IXR05_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4260483.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="IXR05_001997"
     CDS             8542..9102
                     /locus_tag="IXR05_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4260484.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="IXR05_001998"
     CDS             9301..11022
                     /locus_tag="IXR05_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAQ4260485.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="IXR05_001999"
     CDS             11187..12329
                     /locus_tag="IXR05_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4260486.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="IXR05_002000"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="IXR05_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAQ4260487.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4751 a         2298 c         2833 g         4036 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttg
//
LOCUS       DACGDM010000065        13764 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.067, whole genome shotgun sequence.
ACCESSION   DACGDM010000065 DACGDM010000000
VERSION     DACGDM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.067"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            255..569
                     /locus_tag="IXR05_002001"
                     /pseudo
     CDS             255..569
                     /locus_tag="IXR05_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(874..1434)
                     /locus_tag="IXR05_002002"
     CDS             complement(874..1434)
                     /locus_tag="IXR05_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4260488.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            1576..2190
                     /locus_tag="IXR05_002003"
     CDS             1576..2190
                     /locus_tag="IXR05_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260489.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            2379..4259
                     /locus_tag="IXR05_002004"
     CDS             2379..4259
                     /locus_tag="IXR05_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4260490.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            4338..4565
                     /locus_tag="IXR05_002005"
     CDS             4338..4565
                     /locus_tag="IXR05_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAQ4260491.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            4570..5112
                     /locus_tag="IXR05_002006"
     CDS             4570..5112
                     /locus_tag="IXR05_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4260492.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            5339..6055
                     /locus_tag="IXR05_002007"
     CDS             5339..6055
                     /locus_tag="IXR05_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAQ4260493.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(6115..8133)
                     /locus_tag="IXR05_002008"
     CDS             complement(6115..8133)
                     /locus_tag="IXR05_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAQ4260494.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8146..9144)
                     /locus_tag="IXR05_002009"
     CDS             complement(8146..9144)
                     /locus_tag="IXR05_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260495.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            9342..10583
                     /gene="sstT"
                     /locus_tag="IXR05_002010"
     CDS             9342..10583
                     /gene="sstT"
                     /locus_tag="IXR05_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAQ4260496.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            10730..11365
                     /locus_tag="IXR05_002011"
     CDS             10730..11365
                     /locus_tag="IXR05_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4260497.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIARLSILHLKQ"
     gene            11556..12296
                     /gene="truA"
                     /locus_tag="IXR05_002012"
     CDS             11556..12296
                     /gene="truA"
                     /locus_tag="IXR05_002012"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4260498.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(12441..>13764)
                     /locus_tag="IXR05_002013"
     CDS             complement(12441..>13764)
                     /locus_tag="IXR05_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260499.1"
                     /translation="TMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGE
                     AVALTFLPLILMGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSF
                     YFWDQKIARLLSLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLT
                     HILNNNYNNYTIGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFN
                     HTPVKSLQFVWRLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVS
                     NSIHANKDSLTLIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTT
                     HFMSNKLTIELDNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGI
                     NKVVITYQYTKLAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
BASE COUNT         4619 a         2169 c         2681 g         4295 t
ORIGIN      
        1 attacatttt tttcaatatt agcttactag agaataagaa aaagtaagta ataaaccaaa
       61 tttaaacttt atattataat aatgaagctt aatcttcttt atagagaatt gggctatttt
      121 taatggcaaa gaggggaaga agatgtttca aaacaaagga caacgctatg ttgtaaaagg
      181 agtaaaggaa tcttactgga atcaaaaatc tttattgaga aaattatctt tgaatttaag
      241 cacaaagaaa tgaaggtaca ctagatagca atgaagatat ctttgtcatt aaacgtcgct
      301 attttacaca agtaagtgat gatttgattc atgtcttttc caatgagtgg tttgtttctg
      361 agaaaaaatt acatgcttct aatctgcaat atatgccagg tgaagatcca attcctaata
      421 tgaaagcaat tatcaacagt aaggattacg aaggatataa agccaaacat ccagaagcga
      481 aaccatttaa atacccacaa gaaatgaagc gagcatggcg taaaatgtta gatgatgagc
      541 tgattcccct tgaaaatgaa ttgaggtaaa cgagaagaat tcaataaact ggatgataaa
      601 aatataatat gactataaat tggttacagc ttcaacctat aagttgtaat aaattagcct
      661 aaaagtaatt tattaatgat gaggtgaatt tgattggtac aacaagatat atcacttaga
      721 gagggagaag cagcactaca aactactttt caataagtag gaattataga aattttactc
      781 aaaaaatctt cagtaaacaa tttggctaaa taagattcag ttgttatacg agaaggttac
      841 ggttcttctt aactaagctt agtatgtttt tattcaaggc atgattttct ctatgtgatc
      901 attcagtttc tgtaagagtt ctaataattc ttttttggag tacttgtaat tgctttctac
      961 ccaccgattg agaacggata gacaaccttg gacgtggtac gtagtaaaga atctcatttc
     1021 ttctgtgata atcgttttct tgtcttcata tagccatatg ttcagatagt tttcttcaat
     1081 aacttgttta actttcttct gaaacgaaat atcaccatgg ttgaggataa ataagcgata
     1141 taaaaaagta tttgcgtaaa catagtcaat caagcgagtg tatagttcct catagctatg
     1201 ggctggatca taagagagaa tttcatttag atcccgaaaa aagttgcttt ctaattgatc
     1261 atatagatca tagatatcct tataatgtgt ataaaaagtc gaacgatgta catctgccgt
     1321 ttctgttagt tcgcgtatag tgattgcttg aatcttttta tttactaata atgtggatag
     1381 tgtttcagcc aaagcttttt ctgttttttt gacgcgtcta tctgtctttt tcatttacct
     1441 atctccttat ccgacatatc aaagcaaagc tgtcgcttaa tcgacaaact tatagatgat
     1501 tgattataga tagtagacac tgtgtctatt ataatgtaag tataacacaa tcattgaagt
     1561 tgaggaggcg aaatgatgaa actaactttt aaacccttag aaaagaaaga ttacaaaaaa
     1621 gctatctatt ttgctgttga aggaatgaac tttgagagat atatggaaaa tgaacttctg
     1681 ctgaatcttt acggaagata ttttttgtat atggagttga atcgagcaac tcaaattctt
     1741 gctttgtatg cagaggacga gttggcaggt gttttgctgg cggagataaa aggagaaaaa
     1801 aagaaacatc gttcttttgg acagcaaata tatgttaaga tattcgattt tttacaaaat
     1861 atatttgcta aagaaagtaa aggagcttac gagacagcaa atgaacaaat gcttgcagca
     1921 tatttaaaga agcattcgcc agatggagag atcatttttt tagctgcaaa tcctgatttg
     1981 aaaacaaaag gcatcggtac caagttgcta acagaatttg aaaaaagaga gaaaggaaaa
     2041 gaaatattcc tttttacaga tagtggctgt acgtatcaat tctatgaacg acgtggattt
     2101 gaaagactaa aggaaaaaat tagcaagata aaaatcttag ataaagaaat agatctccga
     2161 tgtatgctgt acaggaaaat cattcaatga aaatttcgat agaaacgaca atagttggca
     2221 agatcacttt tagtgagtct tcttgctaac tattttttgt agtgtattct accaaaagaa
     2281 aaccgccttt ttgactaaac ttgatagtgg tcaatttttt atgatggata agtatctata
     2341 cttagtctcg taagaatgaa aggaaaagag ggagaaagat gaaattacaa aagtggatcc
     2401 aagagcatcg aaatcatatc accgccttat cagctgtgtt gattattttt ggttttatcg
     2461 gaaaatttac tggttttgtc ttgttctata acattgctct agccatagct tctattattg
     2521 cggtcatacc tattatgatc catgcgtatc aggcagtgaa agtcaaagtt atctcaattg
     2581 atttactcgt tactattgct gtgcttggtg cctttatgat cggagaatac aaggagtcag
     2641 ctatcgttac attcttgttt ttgtttggta gctatctgga acaaaaaaca ttgaccaaaa
     2701 cgcgggagtc aatcaaggct ttgaccgaga tggccccatc tactgctagt gttgtccaag
     2761 aagatggaac gactgaagaa gtggaaatcg atgacgtgga agaaggcgat atcgtcttag
     2821 taaaaactgg tggagctatt cctgtggacg gacgagtcat tgacgggaaa gggtatgcgg
     2881 atgaagccgc agtgactggt gaatcacgac aagtcgtcaa aatcagtgga gatgaagtct
     2941 tctctggaac gattttagca gatggctacg tgacgattga agcaactaag gtcggagatg
     3001 atacgacctt tgccaaaatt atcgaattag tagaagaagc acaagatacc aaatcccatg
     3061 cggaaaaatt cattgatcga ttttctcagt attatactcc aaccgtttta cttattgcgt
     3121 tggttgttgg tctgattagt cgtgattttc gtttagcaat cactgttttg gttcttggtt
     3181 gtcctggcgc tttagtcatt ggtgcgcctg tttcgaatgt agcaggaatc ggtaatggag
     3241 cgaaacgggg catcttagtc aaaggcggtg aagcaatgga tactttttcc aaaatcgata
     3301 cttttgtctt tgataaaact ggtacattga ccaaaggaac tactgctgta tccactatca
     3361 agaactatac agaggatgaa ggggacagct tagctttagt ggctcgatta gaaacgttat
     3421 ccgatcatcc tctggggcgc gccgtgatcc attatgctca ggagaaagac attgattttc
     3481 aacaattagc agtcaaagat aatcagacaa tcaagggaca aggaatcaca gctgagattg
     3541 atggtcatac agtttgtgcg ggcaacacca aattgattgc cgctcacaaa ctttctctca
     3601 caccaaagca agtacaagat ttacatcaat tacaacaaac aggcagctcg gtcattattg
     3661 tagcaatcga caaaaaaatc actcaaatca taggtgtgtc agatgtgatt cgaccagaag
     3721 tcgctgaaca attagctaag ttgaaacaag caggagcaaa acagttagtg atgctgacag
     3781 gtgataatca gatgactgct gattatgtag ctgatatgtt aggcattgat gaagtccatg
     3841 ctgaattatt accagacgaa aaggttcaat ttgtgaaaaa ataccaagaa caaggattgc
     3901 gcgttgcttt tattggagat ggaatcaatg attctccctc tttggctgcg gctgatatcg
     3961 ggattgctat gggatcagga acggatgttg ctatcgaaac gagtgacgtt gtcttgatgc
     4021 aatctaattt tgaatcgttg gttcatgcct accgcttggc taagaaaact gttttaaata
     4081 cccgtgaaaa tgtagtgatt gccattggtg tcgtcttatt tttactcaac ggcttatttg
     4141 ccgggtttat ttacatggct agtgggatgt tcgttcacga agctagtatc ttgatcgtta
     4201 tctttaacgc gatgcgttta ttgtattttg gacacgaaag caaagaagaa aaatcgtaaa
     4261 acttgataag aatcaatttt tttatggaag ctgtaatcta gaataagact atcaagaaaa
     4321 aggaaggaag aactacgatg aaaaaaatta ttatgcaatt agatacacta gcttgtccaa
     4381 gctgtatgca aaaaatcgaa catgcggttt ctcaacagcc tggggtaagc aatacgaaag
     4441 ttttgtttaa tgcgagcaaa atcaaagcaa actttgatcc agatgaagtc caccctgaac
     4501 aattagctgc agttgtggaa aaattaggtt atgaagtcca atcagcaaaa gtaaaagagg
     4561 cgtaaatcaa tgaatatagt ggaagaaaaa tttgttcaag aaacaaaaca agcagatatc
     4621 gaccatcata aaccaactgc tggcgccatg gtggggcatg tattagcaaa ttttaaatta
     4681 gaagaaatga aattgatcca agcacaattg tatgttttgg gtacatcttc gcaagaatta
     4741 agtacccttt tttcagaata tgctgatcaa gaagcgagat ggttcaataa aatctctcat
     4801 gagttagtga ttgaaaatga aatcgttccg tctactttag aagaagtcat gcgttatgga
     4861 aaaatttacg aacatggtca aaacaaatat ttaccagcct caacaatgtt ggaaaacttt
     4921 gcaaaagatt ttgatttcca aaatgtcttt atcacacggg caatcaaatt agctgaaaaa
     4981 gaagaaaaat atggcttgca acaattgctt gttgaacttt taagtttcaa taaagaaatc
     5041 atctaccaag tacaaagact ccaaggaaaa actgtccgac aagatttgga tgaggaagac
     5101 gatgatgact aaaagtctat gtttcttcaa atacaaatat aaagcgtgag gtaaattgga
     5161 aaatcacgaa gattaaaata aaagaagcac ccgctgatgt attacagaca acatcagcgg
     5221 gtgcttctca gtttttagaa gatttgaaag attgatgaga aaatacgaaa aatcaataaa
     5281 atcacattgc ttatttgata gaataaagaa gtgggagtaa tcgaaaggag ttttttaatt
     5341 gaaaaaaagg attttagtaa caattggtct agcttttttg ttagctggtt gtaccaacgg
     5401 gaatgaatcg aaaaaagaat caacaaaaga aacagcgaaa gcaacagttg caactactac
     5461 aacaactagc acagagagca agtcaactgc agcaagtaca gaaacagcag atacctctac
     5521 ttcgtcagag tcttccaaaa cgactgaaac aactcaaaca tctacttcaa gttcttctgt
     5581 agaggcttca tcttcctctt cagaaagcag cgaacaagtt gaacaaacac tgtggaatgc
     5641 agacaaatcc gcacaattag aggcatttat gaccaaatgg ggccaaacaa tgggacaaca
     5701 atacaaaagt tatacgaatc aaatgagtgt ggacttatat ggtcttaaag tccctcaagc
     5761 tattttgaac ggggagtgga agatggctat tggtggagtg cctgtttctg cagaatggtc
     5821 agaaagtggg acaggtcaag cagactatca aatcacagcc gtctattccg atgcagagac
     5881 agaaccatat ctgaaaaagc acgtctatct attcgggttt cagcaaaatc agccaaaagt
     5941 attggtgaca caacaaaatc aggggaatcc cgataattat ctttacttca acgagacagc
     6001 gaataatgaa ttgaaaaatg gctttaatca aatcgtttat ggacaagcaa attaatgaga
     6061 taaacaaggg gttgtgacat gtcttttatc acaacccctt gctcagttta tttgttagtc
     6121 ttttattttt tgtgtcgccc atgttgcact gtactggtta cctgcaacaa gatcatattg
     6181 tatcagacga taatcttcta gaatttcttt ttgtttctca gttaaatttt tttcttggat
     6241 aatttgacta tcctctgtaa caaagacctg ttttccatta aaacgattag acaagctttc
     6301 tgtaggatca attgttaatg caggtagatg attagatact tctgtcaaca acgcatagta
     6361 aggagttact ttgatattcg catgctcaag agccatagca ccaaagttat taggagcaac
     6421 aacttcttta tttaacgtag ctgcttgttc acgactatac ttgttgttat aaatgaaata
     6481 atctgtctgg tgctgttcta atccatattt tttcgaatca ttcccactat agattgcggg
     6541 taaatggtca ccataaaaaa caaaggtaat cggtttatcg attttgtcga tttcttggat
     6601 gaattttttt actgctgtat cggtatagtg aaggccttgc atataagttt gtaattcttt
     6661 tcttctatta ggaatgacag cagttccttc agcagtgtag ttcaattcac tatagtaatc
     6721 atcataaggc atatggtttt gcatagtgga taattggatg aattgtgacg tttccgtatt
     6781 gctttgtaaa gctttcaagg tttctttgta tgctgaatca tccgatatgc gtgggctttg
     6841 ttctatttta tccgtataag ttaatttatc cggactgtct aaataataga acctgtcaaa
     6901 accaaattta tcaaacactt gttttctgcg ataaagagca gctgtaaaag gatggatggc
     6961 tattttttca tcgaatagat cggtaatatt tggacttatt ttctgacgct ccactagctg
     7021 ggtataaggt gtaactaacg aagcagacag gttactgata ctcaagcctg tcagtccttc
     7081 ccattccatg ttagctgttc cgccaccata accgacggat aacatcaatc ctcctgttcc
     7141 ttctgttata atgcttttga tgtaaggaat agggtctgta ggtactgtca gattagggac
     7201 acgtgcagga tcactgaagc tttcacttaa attgagaacg atcgtctgat tgtttaacca
     7261 gtcacttctt gtttggttga tttcatctgc ctttgtgttg tactttttca ttattccatt
     7321 aattttttct ttcgaatagc cagcaggttc ttccatgatt ttaatgtcga tattgtttag
     7381 gaattgaatg actggtccgt tatcttttac ggcgccttgc tggttaaaga aagtcttgtt
     7441 tactttaaat aaattaaaca gcaagaaaga aggcgaattt ttgtgattaa tgaaaaagac
     7501 acccgaaaaa catcctaata atacagcgat actgataaat cgacgtttcc aatgaatctt
     7561 caaggaatac tgtttttgta gtctacgttg tacaataata ctagtaatca ataataggag
     7621 aaggatcaat ccgcccacga ttaataagac tgggctaacc atcgataata gttctgacaa
     7681 tccggtcagc atttttaaat ctgaaggaaa gacaggctct tcccgcattt ccattttgat
     7741 tactgtcgaa atagtgagca gtaagttaat gatcaaggta gcagtcaagg cgtaccaaaa
     7801 acgattggaa atcaacaata gtaagaagaa aaatcccata ataatgatga ttgtcaggat
     7861 catgggtgct tgtcgctgag taaatatttt taaggcaacc tggatagttt ctttccaacc
     7921 ttcttttggt tctaaaacga aaatctgcac gaaggtaaag cagtaaaaaa atgctgcaac
     7981 taaaaaataa cttttatgaa caaaaagcca atgaattctt tttttccaac gctgagttaa
     8041 ttgttcaatc gaatcaaaag cgaagtattc gatgaaacga tgaatgaaac ggattttttg
     8101 tatataaaat aaaaagataa ctaggaggga cactgctaat aaatatcaaa taaaaaactg
     8161 cccgatattt atcagccatg ccttccctga gtttggaaat tcacgtttca taaatgtaga
     8221 tacgcgataa gaaactaaag ggaaattaca tataacttga gtgacaatca aaaatacagc
     8281 aagaaaattt cctcttcctt ttatacctaa tttatcagat agcatttcta aaaataaaaa
     8341 cgaagagaaa gtataataca ttgcgaagag agaatatggt ttagaaaacc tcagcgctgt
     8401 atctgtattt cctctgatga tgagtgaaat ttgtgtcatc aaaataatca aaccgaataa
     8461 aacaatcaag ctgataaata cttgaggaag cttatagcgg accttttctt tccagttcca
     8521 ttctttcaaa ccataaccca ttaaaaataa ataaaaaatc cataaaatac tctgtccatt
     8581 ctgtaatgca aacgggtctt tattaaatag agtagagcag ccaactaatc caattgttaa
     8641 aaataatagt agatatttaa ttgttgtttt cgataattta tttaaaaatc caactgtata
     8701 aggaatacta caaaaaagca aagtacaaga aacagcataa gtaaagtaat tctgactgat
     8761 aggtgttagg ataagccaat aatcacgaat attcaagctg ccagcttgta cgtaaaaaaa
     8821 gatattgcaa actagtgtgg ctattaggaa tataaaggca aaacgactta aataatgtaa
     8881 aacttttaaa cgggcgattt tttgatattg gtaacccatg taaagtggga tcaaatttgc
     8941 accaataaca acggaagttt gtaaaaatgt atagatgtag aatcgaccag ggtttgttgc
     9001 atatgtagga atagtgactg ctgaaatcaa tatacgctgt aaaaccatca ttatacaagc
     9061 gacaaagatt gtcaggaagc cataactctc cttctttatt tttttcaaga ataaacacct
     9121 cacaaaaaaa ttggacaaaa acataagaaa acgtttcctg ataagttgcc cattaataac
     9181 atcctaactt agaatatctc aaaaaacaac gtgtagacag aaaaagtaca aaattagcaa
     9241 gaaatggttg tttgtattgt tagaattttt agaaaattat acctttagtt tctttgcata
     9301 aaatgataca atgattgtta aaattgtgaa agggtggtca tttgttagag aagtttttgg
     9361 atatgtcgtt agttcaacgt attgttgttg gtattttagt cggaatattg tttggtatct
     9421 ttttccccac atggacattt atttcaatat tgggaacgtt gtttgtcagt tgcttgaagg
     9481 caatcgcacc tattctggtt tttttcttga cgatggcgtc aattgccaag cataaaattg
     9541 ggaataagac attcgtgaag cctattttga tcttatattt agtgggaaca ttgctttctg
     9601 cacttgtagc agttattgta agttcaattt ttactgttcc tattacttta caagaaacag
     9661 tatctgaaaa agcaccgcaa agtttggaaa gtgttttatc tactatgttg acgaatgtca
     9721 cacaaaatcc tgttcaatct cttattgatg cgaattacct tggcgtctta ttctgggctg
     9781 tattgttggg actagctttt cgagcacgtt cagaatcgac aaaagagttg gtggatcaga
     9841 tatctatagc gttgtcacaa gtcgtacaag tgattattgc atttgctccg atagggattt
     9901 taggattggt ttatcaatca attgctacga ctggaatcgc tggattggca gagtatctgc
     9961 agcttttact tgttttgatc ggtacgatgc tgtttgtcgc attagttgtg tacccattcc
    10021 tcacgttttt gtttattaaa gaaaatccct atccattgat tttcttttgt ttgaaagaaa
    10081 gcgcacttcc cgctttcttt acccgaagtt ctgccgcaaa tatcccgata aacatgatgt
    10141 tggctgaaag attgaaattg acaaaagagt cttattccat atcgatcccg ttaggtgcta
    10201 cgatcaatat gggcggtgcc gcgattacca tttccttgat gacgttgact gctgtacatt
    10261 ctttagggat tgaagcacct tttgttttga aagtcctttt atgtattttg tctgctttag
    10321 ctgcttgtgg agcttcaggt gttgcgggcg gttcactgtt attgattcca ttagcatgta
    10381 gtttgtttgg tatctctaat gatgtcgcga tgcaaatcgt cggtattgga tttattatcg
    10441 gtgttatcca ggattcaatg gaaactgcct taaattcgtc aagtgatctg ttgtttactg
    10501 caataggaga gctaggcgcg cgtaaaagaa gtggggaaaa aatcaaattg aaagattgtt
    10561 tagatggatt aagtgaacgt tgaacgttag atatttagta tttttaaaat gattcgagtt
    10621 tttaatgagt tatatagatg ttcgtgtaaa tagaggtttc tgttaaatca agataaagtc
    10681 gtttataata acaattaaaa gcataggtaa ttgttattgg aggcgtatca tggatttttt
    10741 acgtaaattt ggttttttct ttttattatt aggcgtgctg agtgattttt tgactccgta
    10801 cgtattagga ttgtattatc ctgaattaga tcaaatgaag agcgtgatca gtgtatttgg
    10861 agaggtttcc agtcctgtaa gaaaagcgtt tcttatttgg tctgtggttt cagggatctt
    10921 tttcatcctg tcattgcctg cattgtatgc tgcatttgtt agtacatctc gtgtgttagc
    10981 taccctagtt acagcagcca tcgcgttcta tggtataggt gattgtatct ttacaggttt
    11041 gttcagtatc aatacccatg aatcttcgtg gaatgtctcg acatgggtcc ataatatcgg
    11101 atcaggttta ggttacagtg gttttttatt gtttccagtt cttcttttct tgatctatcg
    11161 aaaaaatggg caaatggacg taagccactt ataccttgga ctgtctgtga tcagtttgct
    11221 ttttgcggcg atttatggac tggcaagaat tccttctata aattcttggc cattactgaa
    11281 taaaataggt ttttgccaaa gaatcagttt tttctttaat tatgtgccca ttgccaggtt
    11341 gagtatcttg catctcaaac agtaaaactt gagccgtcaa attgaacagt cagcggatac
    11401 ttcatccggt ggctgttttt tgtttttctg aaatatatat ttccacagtt ttcttgtata
    11461 gcttctgtct tagagaagca aggagctata ttttgtgcta caatcttaaa aaggtagaga
    11521 gaagaccaaa tggaagacag aggagccact aaaatatgag aaacatcaag ttgacaatcg
    11581 aatatgacgg aaaaagatat tcaggatggc aaagacttgg agatgacgat aaaaccattc
    11641 aaggaaaaat cgaaaaagta ttgcatcaga tgacaaatga agagatagaa attattggat
    11701 caggaagaac agatgctggc acccatgcgc gaggacaagt agcaaatttt aaaacaaaca
    11761 cagaaattgg actggcagaa atgatcgact ttatgaatcg ttaccttccg cgggatattg
    11821 tcatcaaaag aatcgaagaa atgcctgagc gcttccattc aagatataat gcggtgggca
    11881 aaaaatacag ctattatgtt tggaacaacg tgattccttc agcatttgag cgaaaccaca
    11941 gcttttattt ccctcaagag ttggatatgg acaagctgaa tgcagcttgc gaaaaattag
    12001 tgggtacaca tgatttcatt ggtttttctg cattgaaaaa atcaaaaaaa tccacagtgc
    12061 gtacgattga tgaattatct atcgaacgaa agggagaaat gcttcatttt acttttgtcg
    12121 gagacggatt cttatataaa atggtgcgga ttatcatggg gacattacta gaaatcggca
    12181 caggtgccat gccgatagaa acaatcgatg aaatatttga aagcaaagtg cggcaacatg
    12241 caggagaaac cgtccctgca caaggtctgt ttttggatga agtttattat cgataaaaat
    12301 actttgataa tggatgaaac gcatgtttca cagtataaat atcgatgtta aataatgtat
    12361 gaagcaaatt aaagaaatat aaaaaaagac tttttagcct gtttatgtgt acagctaaaa
    12421 agtctttctt aaataaaaat ctagtgagaa tgttgtactt ctcttctcgg ttgtttttgt
    12481 ttagaaaaag taaatcgata aagtaaaaat aaaatcaaag taacgataga taaatatctt
    12541 gaagcaattg ctagttttgt gtactgataa gtaataacga ctttatttat acctggagga
    12601 atagttaatt cagttgtgcc aaacttagat aattttgttt gtactagttt gccattaata
    12661 gaagccactt gccctttata acgataaata ggtgtcgtca agacagtatt tttattattc
    12721 gaattatcta attcaattgt aagtttgtta ctcataaaat gagttgttgg atttatttcc
    12781 tggttaccta gtaaatattg atcattatta atcatatcag gatgatagat tgactctttg
    12841 tttgcataat cagtatgatt gtaattttca gctatagcaa cagcgtcttc aggtgctata
    12901 agtgttaatg aatctttgtt agcatggata gaattgctta ctcctgagag atgcaatatt
    12961 agtgcaagaa acgtaaagac cattattttc catgaattat ttttagtaga aaaaatataa
    13021 tagatcacta tactcatcgt ataggctata aataaagaag aaaaaccatt taaccgccag
    13081 acaaattgta gactcttaac tggtgtatgg ttaaaaagtt gccaaggaaa taaattggtt
    13141 gaacaaaaaa gaacaaatac accaagaaag aaaataaata aatcatcagc agttaatttt
    13201 tttataaaaa taaaagcacc aatcaatccg agaaataaga ataatccaat agtatagttg
    13261 ttatagttat tatttaaaat atgtgtcagc atatcactag gagccatacc acttaattct
    13321 tttcccagtg ggactttcaa ttcttgtgct ctagattgtt gaataaaagg aattaagaat
    13381 cccgcactta aaaaaaaggt gaggacggta gcttttaaaa gacttaagag tctagcgatt
    13441 ttttggtccc aaaaataaaa agaaagaaac aacgttcctc caataaatac agaaaccata
    13501 gcgacagaaa gtaaatgagt atacactact agcgtcatgc caatagacaa ccagtaccat
    13561 ttttggtaat ctctaatata aatttcgtaa caccccatta gtatcaaagg caaaaatgtt
    13621 aaagcgacag cttctcccaa tgaagcacga tggaatatgt caatggcacg ataggcggaa
    13681 aatgtataaa taatcgaaaa taacagcgaa atataacgat tgttttttat ttgtttcata
    13741 gaaaaataag aaacgaccat tgtt
//
LOCUS       DACGDM010000066        13739 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.068, whole genome shotgun sequence.
ACCESSION   DACGDM010000066 DACGDM010000000
VERSION     DACGDM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.068"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            206..544
                     /locus_tag="IXR05_002014"
     CDS             206..544
                     /locus_tag="IXR05_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260500.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(749..1324)
                     /locus_tag="IXR05_002015"
     CDS             complement(749..1324)
                     /locus_tag="IXR05_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAQ4260501.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(2056..2637)
                     /locus_tag="IXR05_002016"
     CDS             complement(2056..2637)
                     /locus_tag="IXR05_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4260502.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(2820..3446)
                     /locus_tag="IXR05_002017"
     CDS             complement(2820..3446)
                     /locus_tag="IXR05_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4260503.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(3468..4799)
                     /locus_tag="IXR05_002018"
     CDS             complement(3468..4799)
                     /locus_tag="IXR05_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAQ4260504.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(4954..5355)
                     /locus_tag="IXR05_002019"
     CDS             complement(4954..5355)
                     /locus_tag="IXR05_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4260505.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(5441..5647)
                     /locus_tag="IXR05_002020"
     CDS             complement(5441..5647)
                     /locus_tag="IXR05_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260506.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(5742..7244)
                     /locus_tag="IXR05_002021"
     CDS             complement(5742..7244)
                     /locus_tag="IXR05_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAQ4260507.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7262..7717)
                     /gene="argR"
                     /locus_tag="IXR05_002022"
     CDS             complement(7262..7717)
                     /gene="argR"
                     /locus_tag="IXR05_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4260508.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(7815..8432)
                     /locus_tag="IXR05_002023"
     CDS             complement(7815..8432)
                     /locus_tag="IXR05_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260509.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKPFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQLVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            8653..10026
                     /locus_tag="IXR05_002024"
     CDS             8653..10026
                     /locus_tag="IXR05_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4260510.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10101..11213
                     /locus_tag="IXR05_002025"
     CDS             10101..11213
                     /locus_tag="IXR05_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAQ4260511.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWSTEDYQKDISTYITKNPS"
     gene            complement(11285..12922)
                     /locus_tag="IXR05_002026"
     CDS             complement(11285..12922)
                     /locus_tag="IXR05_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAQ4260512.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13090..13698)
                     /locus_tag="IXR05_002027"
     CDS             complement(13090..13698)
                     /locus_tag="IXR05_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4260513.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         3705 a         2890 c         2464 g         4680 t
ORIGIN      
        1 cctttggaag tatttttgag ttacgtaagt attgatgatc tgtctaactt aatttgacaa
       61 ttaagaaact aaaaaaataa tccaagaaac attgaaccta tggatccaaa agctacccaa
      121 atactatagc taaccccccg ctaccttcaa ttttgcagat aaaacgcttt gggagaaaat
      181 ttcaaagaca acaggccatc ctatcatgcc cgattataaa caaaaagctg gctattcctt
      241 ttgctctgac aaatttcaat tgggaaagtt cacgaaacta gcaggtgaag aagtttcaac
      301 tgttcggatc aaagaatgcc cgcttcaaat agaaacattg gttcaacgaa tttcaactag
      361 acaagacttt gctattgtag aacgtgagat cgtagctatt tttgtagaag aagggatttt
      421 acatgatcca actcatatca atgtggataa atggcaacct cttatctata aattcagaga
      481 atatacaact gccaaccagt cgttaacttt gaattttaga ttccaagaat tcaaagagtc
      541 ataatgataa acatcgttag gtataaataa aaaagactcg cagcacgagt aaaaaacaaa
      601 tagaagctat acattagaaa ggtcgactgt gaccctatag atgcagtata tgcagcttat
      661 gagcatttct tctgttctct ttgtttttgg gatctgtgct gaagtctttt tcgttttttg
      721 ccgctctttc tttgaaaaat cgattatgtt ataccttctc cattactaat tcaggcatct
      781 gctgagtaat gatttttcgc gcaaaagaaa tatctgttac ccaaggttcg atttgttctt
      841 cagtcaagac aagcggcatt cggtcatgga ttggtgcgac tgtgcggtta ggttcagtag
      901 tcattatgat tgattctgcc attttttcat cctgatggct acgataaaaa ccgccaatat
      961 acactatttt ttccttattt gaaaacataa atttgtcttt ttcttcattc cactcataaa
     1021 agccactcat tgggaaaaca caacgatttt gcaaaaatgg ttgatgaaag gtcttttttt
     1081 cttctactgt ctctgcacgg gcattaatca tcaattgtcc ttttttaaat ccggtaaatc
     1141 cccacttcat gatttccgga gtgaggatgt tttcttcctc ttttcttaac gtcacaacaa
     1201 gatttgacgg aaaaacttct ccagctgcta attctgctgc ctgcttcggt tgtttcgtct
     1261 gggcttctcg ataataattc tgaaggagct ctgactctag atcaaaaaaa taacgaccac
     1321 acatcctaat ccctcccaat ctttttttct atcatacact gcaacaagaa gttcgcacca
     1381 acaaaacgct ttcaattttt gtagaactaa aaaagttgtg acaagtgaca aactctccag
     1441 tgaatggtat tctcctgcca actcctcggt cacaagtcac aatattcaac aaacatgaga
     1501 agctgctttt tgaaattgtt ccttgtgact cggagtgaaa cggcaggctt acgacctctg
     1561 ggtaaacggt gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtag
     1621 aaagccattt tcacaaaatt tttcttaata ctcgaaacta agcgactttt tcacaacctc
     1681 ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat
     1741 atgagcagct atttttattt ggctgttctt attacttgat gcagggcagc tttttcacaa
     1801 cctctccact aaacggtgtt caatcagcta accttcggta ttagctcaaa aaacggcaaa
     1861 atatgaggaa ctattttgcc gtttgtttct ctaatactca ggtcaaagcg ctgatttcac
     1921 aacctctaat acacggtgtt ccagaagtag cttcttcgaa aaataagccg aaatttcaca
     1981 aaaatttgag aagcaatttt cgtaaattcc ttcttatttc ttgaagctga ccacttctgt
     2041 cacaacctct aattattaaa gaaccttttg cgaagttaac aatctttctt tgatcaattg
     2101 aaaattctgc ctaagtagtg atagatcctg tgtgactttc aacaataaga tacttccctg
     2161 gatttcagca atcaacgctt tggcttgacg gtctgcttct tcatcggaca gtttttcttc
     2221 agaaagtgcc aggatatttt gtttcgtata cttgacccat tgattgacta attctagtag
     2281 caacagacgg tattcttcat ccactgtact caactcaata atcaaattac ctacaggaca
     2341 gccatgataa gtgatctgtg tctcatgatc agcgaaaatc cagtccaaca tttcttctaa
     2401 tgcttcttct ggctgttttc cagcatttaa gatgtcttcg aacaattctg tctgccatac
     2461 gtccatatgc gcatggatca ccgctagaca aacttctttt tttgaagaaa agtaataata
     2521 aaattgacct tttcctgtat cagaagctgc tagaatatct cggattgacg tttcatgata
     2581 gcctttttta taaataagat ctttggtcgc ttccaagatc ttttcctttg ttttcaatga
     2641 tattctcctt tttcatttct catagtccta tattatacag taaattcatc attttttctt
     2701 cttaatcgtt taaaaaagac tgtgccaaat tatctgacac agccctcact ataaaactgt
     2761 tctcatatag ctagatgttc attgattcaa gaactgcgag gacaaaagca attcctatct
     2821 tatgatagtt gctctaatac ttcctctgtt gtcatcactt gatctgcaat aaagccaaag
     2881 ttcgtcaacg ctgcatccat tgcttcttgg ccaggagcac caattgcatc tgtcgctacc
     2941 acaacattga atccactctc taccaattca cgcatatggg aatcgctaca caagtttccg
     3001 ttcattccac caagaattac tgtgtcgatt ccattttttc tcaattggag cgccaaatca
     3061 ttgctttctg gtccaaagat tttatgagga gagctgatga tcgtattttc atccaaataa
     3121 ggtttcaatt cttcgataaa atcggctcct gaaccttctt ccactgattc atattgactt
     3181 tttctagcaa acatctgctg ctcaagcatc atatgttctc ctgcaccgcc aaattgccat
     3241 ttatggtcat gtgggtaaaa ataatgagga gaaataaaga gtttgtatcc tttttctttt
     3301 gcttgtttta ccatttcaat catattttcg atcgtattgt atttttctaa gatatctttt
     3361 gtcaaaccaa agccaccgcc tgctggtttc aagaactcga cttgcgggtc agtgagaact
     3421 actgctgtat ttttattatt gaacatggtg gattctccat tcgttattta ttttaataca
     3481 tcatttagag cttcactcat tgtcggatga gaatagattt gatctctcaa taacgtataa
     3541 ggaagttttc cattcatagc tagcgaaatc aagttgatga cttcatgaga atcttccgca
     3601 tagatacttg cccctagaat caagtcagtt tcagggtcga ctaaaacttt gaatacacct
     3661 ttaggatctt ctaatacttg tgctttaggg acaccgcttg tcatatactt gaataatttg
     3721 taattgacgc cttgtgcttt ggcttgtttt tctgttaaac ctacattgga taaagtcgga
     3781 gtgataaata cactgtaagg cacagctttc cggttattcg ttgttcgttt attctcgccc
     3841 ttcaactgat ccataatgat tcgataatca tctagagaga tataagtgaa ctgcaatccg
     3901 cctttgacgt ctccaatcgc ccaaatgttg tctgcatctg tacgaaggta ttcatccaca
     3961 gcgattgctc cgcgatctgt tagtttaaca tctgtatttt ctaatccaag tgatgctgta
     4021 cttggttttc ttccagttgc agccaaaact tttgacgctt ggattgttac ttcttggcca
     4081 tcttctgtaa aggtgacggc agctgttgat tcttggtctg ctacttgatc tacagataca
     4141 cctagatgga attcgattcc cgcatttgtc atgtcttcta aaatcatttg cgcgatatct
     4201 tcatcttcac gtggaagaaa ttcagaatgg gcatcaagaa cgacaacttt agatccgtat
     4261 tcattgaaca ttgatgcaaa ttccaagcca atatatccag ccccgatgat cactaatttt
     4321 tccggtaatt gttcctgatc catcgcttgc gtagaatcaa tcaagtagcg acttgtattc
     4381 aatcctttga ttggtaaaat gattggttca gaaccagtat tgatgaaaat ccgttcgcct
     4441 tcaacaatca ctttttcacc attattcgtc acttcgattt gatggttaga aagaaaacgt
     4501 gctgtaccgt ccatcactgt cccagttgcc tcatcgctga tcatatgata atttttggcg
     4561 cgaagcatgc ccgtcaattt ttctttccga gcaacagcct ctgtaaagtc gattcctctt
     4621 tctccattga aaatcaatga tttagaagga atacagccga tgttgataca tgttccgcca
     4681 tacatacgtg ttgacttttc aacgactaaa accgattcac cttttgaagc taacgccttc
     4741 gctaaagtct taccgccctt tccaaaaccg atcacaatat tttgatattt ttccatcatt
     4801 tttccctcgc ttctttttta cctaccgatt ggtacaaaaa tatgataacc gataattgtc
     4861 tattctccaa atcatctgct ttatttgtca aaaaaaacca gacaaaaagc ggtcctttca
     4921 cgtttttagt ctggttcgat ttcctttatt cttctaaaca atcgttactt ctacatcgat
     4981 atttcctcta gttgctttgg agtaagggca gaattcatgc gcatcttctg caattttttg
     5041 ggcttcttct tcgctgatgc catcgatatg cacttctaat actacaccga tctgatagcc
     5101 gccatcatct aaattataaa gagagacacg tgcttttact gtggactctg ctgtcattcc
     5161 tgcttctttg atcatatgtt gtaccgcccc attgaaacaa gaagcataac ctgctgcaaa
     5221 taattgttct ggatttgttc cttctgcatg gattcctgga ggagtgattt tcatatgcat
     5281 cgagccattt ggtgcctcga cttctccatt gcgcccgcca tggttgatca ttgctgtttc
     5341 gtatgctttt ttcattgtac tgctcctttc gattgaccat ttgctacttg gctataatta
     5401 tagtgtatga caagtaaggc gctttctaca aaaattctgc ttattcgaat accagaatgc
     5461 cgtcttctac tatttttcca aaaaacaaaa aaatactact cgtgaacaac agcgtcatat
     5521 ttgttccaaa ataaatagca atcttttcta cataatcttt tatatgattg attttaagat
     5581 acatatatac cagaaagttg accccataaa ccaatactgt taaaaaaata accatattcg
     5641 ttaccatttt ttcctccttt tgctggtctc cctaccagca ctcgatttaa ccataccact
     5701 ttttttgccg tccaagcaac tagcctttca aaaagactgg tttattctgc tgttaatgat
     5761 tcaagatcag aaaaatgtcc gaataatttt gctaatttta ctaacgccaa cttgttcttt
     5821 ccgaattcat cattttctat ctgtaatact agtaacggct catgtaagct taaacggatc
     5881 aaaaaccagc cgtttccgta tggctcttct agatcatatc gaataccttc ttcattttcc
     5941 gggtcgaagt tcatcccttt ttcttcttcc aacagtcgct tcatttcttc taatatcttg
     6001 tttccttgtt cgcgtggttc atcgctgaac aattttaatc ggatttcttg tacttctacg
     6061 ggctgtttca actctttgat ttgttcatct aatgtgatac cttttctttt taattctggc
     6121 aaaagcatca ggatctttgc gatgacatat gcaccatcat ccagaaaata gttttccttg
     6181 aatgcagcgt gtccgcttgt ttcgatggct agctgtgtat ctttcccaag acggttaagt
     6241 tctaatgctt tattgattac atttcgatag ccggaaatat aacgaacttg gatgcctcct
     6301 ttttcttcaa tgaatctttg tagatgagaa gaagtagggg aattcgtcac gattcttgtt
     6361 cctggatgct cttttaatac gattgtactt aatactgcga tcaaattatt tcgattgatc
     6421 actgttccag aagcactgac aactgcagaa cgatccacat ctgtatcgaa aatgatccca
     6481 agatctgctt catttgctaa aacagcctgc ttgatacttt ccatcgcttc tttattatca
     6541 ggatttggga tatgattagg aaatcggcca tctggttcca aaaattggga acctgttgaa
     6601 tccgcaccta agctattcaa tactttttca gcaaagaatc caccagcacc atttccggca
     6661 tcaacaatga ttttccaacc atttagtggt ttgctttcta gtgttccaat ccccttttta
     6721 atttttgtga ctaaatcttg cgcataaggt gtcaaaaggt ctgctttttc tacgcttcca
     6781 gtttgttcgc tttttatttt ttgctgctgt gataggataa aagcaatatc ttctttttct
     6841 gctcctcctt ctgaggtaaa gaattttatt ccattataat aatagggaag atggctagca
     6901 gtcagcataa ccgcagcatc gcacgagaac tgttcaaatt gagtggacat aaacatagca
     6961 ggcgtagtag ctaattcgaa atcgatgaca tgtatccctt gttctttcag actttggatc
     7021 aacgcctctt tcagtgctgg tccgcttatc ctactgtcat gaccaatccc aatcgtccat
     7081 tttttatttg gatcggttga tttcttcttt ttctttatcc agtttgctag tccccagccg
     7141 atctttttta ccatgtctgt cgtcaagttt acttcatatc cttcaactgg taatgcgatt
     7201 cctcgaatat ccgatccatt ttgcagcgct ttcatatctt tcatataaaa gtcctcctca
     7261 tttattccct cattttttcc agcttttctg caaatcgctg tgcttcttct tctgagcggc
     7321 aaataataat gaatgtatct acaccggcca tcgttccgac aacttcaggg taagccactt
     7381 catctagcca attcgttacc acatcggcac catttcgttc agtcaatacg ataaccatga
     7441 actgaacaga ctggatacgc aaaacctcgc gtctaattgc tgtacgcaaa cgttcttcat
     7501 ttaaagaaac agatggctgg ttaaataatg tatagcgtac tattttgttt tcattttgac
     7561 tttttactaa cttcatttct cgaatgtctc gagaaatcgt tgcttgagtc acatcggcgc
     7621 ctgcttcatg cagccgcgca agcagctctt cctgtgtccc aataggttgt tctgtaatga
     7681 tctggcggat cagtgcttgt cgctgtttct ttttcatatt agacacctct caatgttgat
     7741 tatagcaaaa gataagtaat atttcttcat attttggtat tttttacttt tattttttgt
     7801 tttcattcag gttgctaacc tttttctatt ttaacacgca aaatcgtctt cattttttca
     7861 ggtgctgatt ttcttggatc gctgatgtaa atctctttgt gttctttaga agctctttca
     7921 tagccttctt ttgcgatgaa tgcttctaat ttctcaaacg ttgctggttc ttcggcatag
     7981 ggcccgacgt gtaagatttg ggcacaaaga ccttcttcca tctttttgaa tactagttgt
     8041 tctttcaagt cttccggaag tttgctagaa cgctgaatgg cttcttgtgc tatcgcttct
     8101 gtaacaaagt caggctgtcg gatcatcaat tgataagaaa aatgttcttt tttcatcact
     8161 ggttcatgca aatacttttc ttgcagtccc cattgtcctt ccagtggata gacagtatac
     8221 atctgataat caggaatcag ccaatttttt ttaggcgaca tgcgtattgc atagctgact
     8281 gcatatagac aggctactct tcgtttaaag tcttcctgat tcgggtcgcc gatccctctg
     8341 atgctaaaga atggtttttt aggaacctct agtatttgcg ggcttttttt catactatag
     8401 ctcttgtctt tacgccattc aattttttcc atttttcttc ctccgcgaaa ttccatttag
     8461 ttatttatta tcatacctct ttttgagtga cttggctaat cgtgttgaca ctatttttca
     8521 gtttgtgcta gaataagtga agtaaataaa tcgtacagat aacacgtttc ggcgtgtcga
     8581 gagagaggcg gtttctattt ttataataga aatcactctc tttttttacg aaatttttta
     8641 gaggtgatgt aaatgacaaa acaaaaacag ctgcttttag tacctgcagt aattgcaaca
     8701 gggatgatgt cttttgcggg cgtattgatc gagacggcca tgaatgtaac tttcccaact
     8761 cttatcagac agtttgattt aacgactgca caagtccaat gggtaacaac gatttatctt
     8821 ttgatgattt cgatcattgt tccgctgtct acttatttga atcgcaattt tagtctcaaa
     8881 aaactctttt tagcttcaaa tctgcttttc ttggcaggta taatgatcga tttcttctct
     8941 cctaccttca tggtcctatt gtttggtcga ttgctccaag gtgcagcgac aggtatcgct
     9001 cttccgttga tgttccatat tatcttgaca tttgcccccc tcaatcgacg aggcgcgatg
     9061 atgggtgtcg gtactttgac aacggccatt gctccagcaa ttggccccac ttatggaggc
     9121 attatgactt cacattttac atggaatcat atcttcctgt ttcttgtgcc cgttttgatt
     9181 ctttctttga ttatcggctg gtttgctatt cccgagatgg cagtacaaaa aagtggttat
     9241 ttggattgga taagcgtttt aggaatttgt cttttgttta gtggaagtct aacatttttg
     9301 agtacgttgg gaacagtttc cagctggatt gctttaatca tcggcggtat tggctggttc
     9361 cttttttact atcgaagtaa aaaagtggag catccactga tccgactgtc tattctttca
     9421 aataaaacat tccgcttgtt tttgattggc ttcttagttt atcagttttt attacttggt
     9481 gtatcttttg tcttgccgaa tttccttcag atcgttcaag gaagtagtcc ttttgtcgct
     9541 ggattagcga tgcttcccgg cgcagcggtt ggtgctttgc tttctccttt ttccgggaaa
     9601 atgctggatc aatatggtcc gaagaagcca atttttgctg ggctgattct ttctttgatt
     9661 ggttggctag cattattcct actcatagga cacgcttcag tgggtgtatt gattgcttgt
     9721 catgtgtttt atatgatcgg tatcggatta tcttacagca atatgatgac caccggaatg
     9781 aatgcactga atgaagaact acaaggagac gggaacgcaa tgttcaatac cttgcagcag
     9841 ttttctggcg ctgtggctac ttcattagta gcggtcatta tcaattacgt ccagcatcat
     9901 acttcccata actatgaagt gtctactaca ttaggatcaa aagcagcatt aggcgtcttg
     9961 ttgctgttgc ttctcgtaag ctttgctcga ttcgcctatt atctgttctt tgctaaaaaa
    10021 gcgtagattc catatacggc aggtgttgca tctgccgttt ttttgtgtga aaatggttgt
    10081 ttgtaaaagg aggctttttt atggaaaaaa ttgccattat cggtggcggg atcattggta
    10141 tgactctagc cagttactta gatacatcaa aattcaatgt tgctttattt gatgaaggga
    10201 caggacaggc aactaaagct agcgctggga ttatctcccc ttggttgtcg aaacgcagaa
    10261 acaaacaatg gtatcgtctg gctaaagacg gcgctgcttt tttccctaaa cttataaaag
    10321 atttccaact tgatcaaacg atttacgcac aatcagggac acttttgctt cgacctgaaa
    10381 aagatttagc tgaattggct gttcttgccg agaaacgaaa agaagaagcg ccagaaattg
    10441 gaaacatcga atggctttca cctgaacaga catctcaagc acttccgtta ttgaaaccag
    10501 cagtttcact gcgtatcagt ggtggtggtc gtctggatgg aaaagcatat ttagaacatc
    10561 ttggtcagcg tttagcacaa aaacaaatgg agcagatcca ggcaaaagtc actttgcata
    10621 agaagagcga ttcttggctc atcaagggac cgtttggaga atacacagct gatcgtgtaa
    10681 ttttgacacc tggcccggca cttaagcctt tattacaaga attaggctat gctgcagata
    10741 tacgtccgca aaaagggcag ctcttagcat ttcagacatc ttataagatg agtcaagact
    10801 ggcctgttgc tatgcttgac ggagaagctg atttcattcc tttcatggat ggaaagatcc
    10861 ttttaggtgc tacccatgaa aacgatcaag gctgggattt ggctcctact agcgaagctt
    10921 ataagggatt gactaagagt acagaacagt tcttgactga tccagatcag ataaaaaact
    10981 ggccatacga gttccgtgta ggtacccgtg cttatacgtc agatttttcc ccatttttcg
    11041 gcgtactgcc agatgatcca agcttactgg ctgctagcgg tctaggctct tctggcttga
    11101 ccacaggtcc ttatatcggc tatctattag ccaacttctt aaatactggt cattggtcta
    11161 cggaagatta tcaaaaggac atctccacct atattacgaa aaatccatca tagaaaaaca
    11221 gctttttcaa gtaaggatcc cgagcgatat tgcgcatgga ttacttcttg aaaaagctgt
    11281 tattttagtt caatttctga atcaaattct ccaaactttc ttttgcttca tctggcaaga
    11341 gatcttttcc tatctgagct tcaatgaatc gtaaacgaat atcaagtcgt tgtttcacca
    11401 gatttttata ggacgtatcc tcaaaagaaa caggaaaatc tggtataggt aaatagtgga
    11461 tgtcttcaaa tggaccaaac gacttgaatt ctgccgtttg ttgcacgatt ctttcaacga
    11521 ttgacaatgt cgtttcaggt ttgatttttt tatcatcgaa atatccagta ttcaggacat
    11581 agcaggctgt ttgctgtttc aaaaacaact ctcgaaaagc ttgatagtct tccctaagag
    11641 gatagacacg gaaaggatta gcaaatggtt caatgactag ctcatctagc tgtctttttg
    11701 tagtgatatt ttccgcgtct gatcgttttg ttgctaatgt tgcaccaaaa gacgctgcta
    11761 aaactgggtc attgatcttg ataattggcg gaagcgaatc atctttcatg atccaaaaaa
    11821 cagcatcgat cttttcgcta agatgatcga ctcggtcggg tgtcgcataa cgtgatttga
    11881 ctgtccgccc atttccgttt cgtatatctc ctgttactag gactttttct cctttacttg
    11941 tacatgtcac gcccacattc tgacaagtaa ggaaagaaga aatggccgga tcatcagacg
    12001 gatagtcttg tgttttatca aagtaagaag gttccaaggc agtagcaaaa ccattttttc
    12061 gagaaataac gaaagcatcg tcatgcaaga tcgaaacaga gtgaccttcc gtatgttttg
    12121 ctaaggtaat cgttgatttt ccagaaccgg acaacccaaa tacagccatc gtataggtct
    12181 ggtcattact agcatattgt ttcatcccac cgtggcaggc aataaagcca ttgcgatttc
    12241 ccaatgccca agcaagcgtc aaagtcgctt tttttaattc tccaaagtaa cgtaatccta
    12301 gcacagccgc tgtattatgg agagcatcaa acaaaatgag tccatttgga aatgtttcat
    12361 gtgtccattc gggatcacaa aagatataaa gatctccctc atcaaaggaa acagactttt
    12421 gataagtctc taagatcttc gaattcgctg gctgaaaatt cagcaaataa gaatacaaat
    12481 tgttctcaaa tccttctgga atcagcaaat gactttgcac agaaaattct tcagataggc
    12541 caacgattac ttttgtatgg taaaactggc gcttgcgact ttgatacaca gcttctctta
    12601 aaattttctc gtatttgctt tgttccttgt ctaagtcctc aaagatccgc cgagcacttg
    12661 ctgttcttcc cacaatgctt ccatcattga atactagtgt cctaacatca gctggtaaat
    12721 ctagttcttc agcatgtgag attgttaaat ctgtgatgat cgttcctgga ctcccttttg
    12781 ctagttgata agctgtcttc ctgtcaaaaa cttcatgaac attattaccg taaaatgtcg
    12841 tttctacaat cgatcgaata ctggataaca gtggatttcc acttgtgatt tcgtttaatt
    12901 cgagactctc ttttgtactc atggctcctc ctcattccct aaacaaaaaa acgttttctt
    12961 tattatacat tattcgagtt tttatttgta ctgctgcgct gtgggaagca aacgagttat
    13021 ttttcacaca aaaaaaccga gaacttgaat aaacaagttt ctcggtttca tcattttcct
    13081 tttatcggct tagtaccagc cgtttgctaa ccagaatgtt ttagcagcat cccatgaacc
    13141 ataacgagat gttacatatt gttctgctac acgttcttga ttggcagctg aatagtcgcc
    13201 gtttaagtat gaagcatcta attgataacg gccgatgtaa cgtccgttag tagctgtgta
    13261 tgaaccgcct gattcttttt gtgcgatcca ttcttttgca gagcttgaag ttggcgctgt
    13321 tgcagcagct ggggcagcag gagctacttc aactgtttca acaggtgcaa cgtatgtatg
    13381 ttcttgcgtt gctgtttcag ttgtagatgc tgtattttct gttgttttgt tttctgttgt
    13441 tgctgaagaa tcatttgaag ttgggattgt taattgttca ccaacataaa tgcggttgat
    13501 gtttgcgatc gaattttttt cagcaattgc atcgatcatt gagttgtctc ctgcaaattt
    13561 ttgtgagatc ttagataatg aatcacctga ttttactgta taaacttcat cagcgtgagc
    13621 atttgtagtt cctacaaaca ttgcagtagc accagcagca aaagttgtac ctaaaacaat
    13681 tttcttaaat gaattcatat taaactcctt tttttctccg ttttttattc tttcgacgc
//
LOCUS       DACGDM010000067        13691 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.069, whole genome shotgun sequence.
ACCESSION   DACGDM010000067 DACGDM010000000
VERSION     DACGDM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.069"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(119..1249)
                     /locus_tag="IXR05_002028"
     CDS             complement(119..1249)
                     /locus_tag="IXR05_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4260514.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(1790..1996)
                     /locus_tag="IXR05_002029"
     CDS             complement(1790..1996)
                     /locus_tag="IXR05_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260515.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2012..2626)
                     /locus_tag="IXR05_002030"
     CDS             complement(2012..2626)
                     /locus_tag="IXR05_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAQ4260516.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2773..3456)
                     /locus_tag="IXR05_002031"
     CDS             complement(2773..3456)
                     /locus_tag="IXR05_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAQ4260517.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3565..4023)
                     /locus_tag="IXR05_002032"
     CDS             complement(3565..4023)
                     /locus_tag="IXR05_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAQ4260518.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4107..5870)
                     /locus_tag="IXR05_002033"
     CDS             complement(4107..5870)
                     /locus_tag="IXR05_002033"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAQ4260519.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6091..7551)
                     /locus_tag="IXR05_002034"
     CDS             complement(6091..7551)
                     /locus_tag="IXR05_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260520.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7759..8685)
                     /gene="glsA"
                     /locus_tag="IXR05_002035"
     CDS             complement(7759..8685)
                     /gene="glsA"
                     /locus_tag="IXR05_002035"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAQ4260521.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8708..10135)
                     /locus_tag="IXR05_002036"
     CDS             complement(8708..10135)
                     /locus_tag="IXR05_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4260522.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10166..11380)
                     /locus_tag="IXR05_002037"
     CDS             complement(10166..11380)
                     /locus_tag="IXR05_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAQ4260523.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11721..11963)
                     /locus_tag="IXR05_002038"
     CDS             complement(11721..11963)
                     /locus_tag="IXR05_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4260524.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(11995..12552)
                     /locus_tag="IXR05_002039"
     CDS             complement(11995..12552)
                     /locus_tag="IXR05_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4260525.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12565..12753)
                     /locus_tag="IXR05_002040"
     CDS             complement(12565..12753)
                     /locus_tag="IXR05_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4260526.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(12766..13332)
                     /gene="amaP"
                     /locus_tag="IXR05_002041"
     CDS             complement(12766..13332)
                     /gene="amaP"
                     /locus_tag="IXR05_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4260527.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4100 a         2817 c         2226 g         4548 t
ORIGIN      
        1 taatatgatt ttttgagata ctttcattgc gaattcctct ttctaaaaga acctctcgct
       61 tgaaaaataa aagattgtac tttatgataa ttcaaactga gagtttctca gtttctcttt
      121 attgtttttc aggtcgatag agcgccaact cttcggcctg tatctttgaa gaaatattca
      181 acgtgattcc gattcctaaa gaaaggatca gataacttgt tcctccgtag ctaacaaatg
      241 gcaatggcac accagtcatt ggcatcagcc ccgcgatact tcccacgttc attatcgtct
      301 gaacgaatag caaagttccg aatcctaaaa gaaacaatcc agcttgctga tttttacagc
      361 gactgcttaa acaaaagatt ctcatgcata atgagaacaa taagaaaagc acacacaatg
      421 caccgattag cccaagctct tctgtaataa tcgaaaaaat aaaatctgtt tctgtctctg
      481 gaagataccc tttttttgtg atactatttc ctaatccccg cccaaatatg ccaccattat
      541 atagtgcata aaacgaatgg gtcatttgat agcccgcacc atgactatcg ataaaagaat
      601 ctcttaaagt cgcgatcctt tcataagcat gattaaacat ctgtggaagc caacctttat
      661 ttcctaaata taataccccg cctgctgctc caatcagcaa tgcagaaaaa gtaacgatta
      721 gatagatccc ttttttaaat ggaaccgccg ctgcccaaaa tatgacccac gcaatcgaaa
      781 ggatcatcaa tgctccagca atctttggct gaaataaaat cagaaaagtt atacctactg
      841 taatcaggaa tggttttttt agatcttttg ggctactatt tccgtcacga aaaaaccagc
      901 ttaaataaaa aatcaaaaaa agatttgcca gttcagaagg ctggaattga atgccaaaca
      961 gagagatcca acgttgtgcg ccgttgacag tgacaccgaa tatccctatt cttactaata
     1021 ctaaaaagaa aatcgataag gctaaaccgt atcctgctat tttagggtga agtaaatagt
     1081 gtagtttgac tgaacgagct aagaagatca cgctccaact caaaaatatg aaaattagtt
     1141 gacgcaataa tagacttttt gtattttcat cggcttgcaa taaacgataa gaactggcac
     1201 tgtatacttc taaaagaccg atcatggaca aagtcaaata aggacccaaa atccaccaat
     1261 cgatcttttt tcaccgcatc tcctcctcac acagcaatcc acttgtcagg tgaggagcga
     1321 gtttgtctca tcaaataagt cagtcacaaa aatataaaga aaaggtcaga aaccttttcg
     1381 aacaagaatt ctgacctagc atcatctcat cgtccgagtt ttagcactat acaacgtaaa
     1441 gaaaacattc ttagctattg gaaaaagcct taatccaaca gtttctgttt tacccattgg
     1501 cgactttcga cgtttctggg caacagccta tgtttgtata ggagcctcac ctaacaaggt
     1561 tattactata ttctatttac gagttcatga tagacttttc ctaatgatta ggcaatggaa
     1621 tttgaaatga aatagtgaaa tttaacaatc tttaatattt tttagaaaaa aataacaaat
     1681 aagttgaaag aatcccgttg caaattcttt cagttgcacc aggattcttt gataattttt
     1741 tagttttatg tgttttttta tatgtttttt cacttttcgg aataaatatt tatttgttaa
     1801 agtaattaaa caatccgcta atcgtttgat ctggcatttc tatttcctta ccatctaaag
     1861 taacagtagt aacgacaaaa tggtcttgca atggcggaac ttctaagtac tgcccttgca
     1921 gaaaatcatt cactgtttca tattcttttt tcatttcttt tgaatctgtc gatggtttat
     1981 agcttatttt taacataact agtgctcctt tttattcggg acgtgcaatc gtgaaaattt
     2041 ctcctattgc tgcataatca tttcctgcca aacggcttac agcattcaat tttcttggat
     2101 cgatccttcc tgtcttatca tcatagactg tttcatttaa atgatatttc tgtacttcta
     2161 gcaaaaataa atcagctgtt actttatttt tattccgtat ctcgacatgt tcatataagg
     2221 atgtttcaaa acgaactttt gcttctgtca atgctggtac tgaaatgatt actgaatcag
     2281 ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt aggcagattg gctgctgttt
     2341 tatttacttc ttctacgttg tcctcatcaa ggatatggat aacagcttct cttgtctcaa
     2401 gaatattctt tgctgtgtct tttactgcat cttgttttct ctggatcgcc aaggataaga
     2461 tgggtcgatt cgaactgacg atattgaagt aactgaaggg tgcgatattc actatatctt
     2521 ttgctgattt agtcgttact actgctactg gtctagggat gactgaacca atcagcaact
     2581 tgtaattttc acgttctgtc aattctgaag gactccgttc aaacatggtt tcgccttctt
     2641 tctataaaat tcgttaaaaa gcagatcttg aagacaaaat gaaaagtaat gcttttttca
     2701 tcttcttaga atctgcttta aactatctat caatttttct tttttgtcaa gaatctgtgc
     2761 cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg acatatcttt tagtgatcaa
     2821 ttgcggacgg gtgataatag atccaactac gactgaaaaa gcacctaatt catatgcttt
     2881 ctctacttgt tcaggagagt cagtatgtcc ttccataatt actgggatat cgacttgttc
     2941 tatgatttga ttcaataaat caaaatcagg tgtctgcgtc tttcgtgaat attctgtata
     3001 gcctgctaaa gtcgtagaca aaagatcaaa accatcttct tgcgcttgaa gcgcttcctc
     3061 aaaagtcgaa atatctgcca tagctaaccg accgtgttcg tgaatcattt ggacaagttc
     3121 agcagttgtt ttttctgtcg gacgtttacg agaagttgca tccagtgcaa tgatttctgc
     3181 ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca gtaataaaca cttctgaccc
     3241 atcgtaatct cttttgataa tccctattac cggtaaatca acgattcgct tgatttcatt
     3301 gatatcttct gtcgtatttg ctcgaatacc aactgctccg ccttcttttg cagccaaagc
     3361 cattctcccc ataataaaag aactgtgtag cggctcgttt tccaaagctt gacaagaaac
     3421 gacgactccg cctttgattt gttccagtgt atccacaata tctcctccag taatgttata
     3481 taaaaataca gcttcatata aaaatgtaac ccttttctat tcaggagaca ataatgagct
     3541 atttctttca gcagaccttt cttactaaaa gaaaattact tcaaattctt cgtatacgac
     3601 cagcttctct tctgtaaatt ctatgttcaa cgcttcttta taagcatgtt taaaaaactc
     3661 agcatggact ttccgccaat aagctaatgt ccgatcccct tctccttctt tccaagcatg
     3721 ctctttcgtg acttcactaa aaggcaagat ggtcacattt atatttttga tgatacaaac
     3781 tggttcattt tttccattca ggaccacgtc taattgacca acttttggta aaggctcatt
     3841 ctcttgttta tacagatcgt aaccacttga tgtaccagtc tttatctttt ttacaactag
     3901 ttcgctcaac tcgtctgcca ttttttctgt atccccaaat gaaaagaaac ctaatttttc
     3961 tgattgataa ctaggatatt tttcttggaa ctttttgaca tattcttcta cttgctgata
     4021 cataacatcc acccctttgc tttttataat gaaaaaacca tccagatact agtataaaca
     4081 attatctgga tggtgagcat aatgaattat tgaatattca agacacgcag actatcttca
     4141 acgatttgtt ttggtgttaa atgataacgt tcataaagct gccctacagg aacgctatcc
     4201 gtgaattctt tctctgcacc aaaatttaat acgttcattg aagaatcacc ataataacga
     4261 ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt ctaatgtgat gactaattcg
     4321 tgtgtttctt ttaatttatc taatgtttct acgtcatttt ctgtgatcgt tcctggattg
     4381 atcaacgttg cttcgattcc tttttttcta aaagctttta ctgtttcttt tcctaattca
     4441 agaaaaccgc ctaaagctaa aattgctact tttcctccat tatttactgt ttgataggct
     4501 ggaatactat aatcatttgc gatagctgta ccatgttcta caccatgtgt aggaattcgg
     4561 attgctacag gctgcgctgt ttgttcgaac gcccaatcta gcatagagat catatcctct
     4621 tttgttgctg gagcaagata tttgatgttc gggatacttg ataagtaagg aatgtcaaat
     4681 gttccttggt gtgttcggtc actagctgag atcgttccgc caccgactaa aataatcact
     4741 ggattctcgt tgatcgctaa atcatgtgat aattgatcat atgcccgttg caagaaagta
     4801 cttgattgga agacgactgg acgtactccc tgagaagcca aagcagaagc gaaagtgata
     4861 gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg gatgtttttc ttggaatgtt
     4921 ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg caataggagc tgtacttgtt
     4981 tgcattttct tatccaaata atccatgatg atcatattaa atgtttctcc agaagttact
     5041 tgctttgcct ccccggtgga cagatcaaat ggtacatgcc aatgatattt cattttatta
     5101 tcgattgccg gctgataacc gcgacctttt tccgtatgga cgtgaagtac aatcggatga
     5161 tcaatatctt ttacttcttc aaataaacgg atcaccgttt ccagatcgtt tccattatcc
     5221 acgtaacgat aatcaaatcc cattgcttta aataggttat tgctgctttt accgttggtt
     5281 tgacgaagct cagctaagtt tttatataaa ctgccatgat tctcatcaat agacatctca
     5341 ttatcgttta ctaatacgat tagattggat tgtaaaacac caccattgtt caatccttca
     5401 aaagctaagc caccacttag ggagccgtca ccgataaatg ctaccacatt tcctgattct
     5461 ttcttcagat ctctcgcttt agctaaacct gttgctaagc tgatagatgt agatgtgtgc
     5521 cccactgtaa aatagtcatg tttactttca tgttggttgg aatatccgct cacttcacgg
     5581 taatgtcctt tttcaaaacc attttttcga ccagttaaaa gcttatgacc ataagactga
     5641 tgggaaacat cccaaacgat tttatccttt ggtgaatcaa atacataatg aaacgcaatc
     5701 gttaattcta ctacacctag attcggacca acgtgcccac ctacatcgct gtccttttgc
     5761 aagatttttt ggcgcatctc ttctgccaac tgtttcattt cctcaacaga taattttttg
     5821 acatctgcgg ggctattgat tgcatccaat acatgtaata ctgtactcat aatacattct
     5881 ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt acactttatc tattctacta
     5941 cttagagttg actctaagtc aatagcattt taaaaaaatt tcagagaaag cttgttatat
     6001 aagtagatct tcgcacgaat caggactcaa ataaaaacct tctacagaca attaaaaagc
     6061 tttgtagaag gtctcctaat taaggtctca tcaagaaata tgttttttta ataggtgaag
     6121 ttcctgagca atatgataca aatggatgtt tgcacctttt aatgagattg gatagatctt
     6181 tgtcttttca gtttctaatc cattttgata gctagcagca tcgcacaaaa ccactctttt
     6241 tttcgcacat agacattcat caggcaattc ttctaatgaa cgaaataaaa taggatttat
     6301 ttcagcgatg ccttcttccg catacaaatg aaattgggtt cgataaaaaa attgtttgac
     6361 tgaactttct gaaacaacaa aaatttctat ttcctgtctc cccgcttgtt cactgttgat
     6421 caaagaaaga cttttgacga attttcgaat gaaattttca ttccatctta gttggatttg
     6481 atttttcttt ttccactctt ccaatatttc tacaattttt ccgtacagaa gttgttcttt
     6541 ttctgataga agatagatcc tttccggtaa aaatacttgt ccatctgccc acaacgtacg
     6601 gacaaattgt aaaaaggatt gcttgaaaat aaaattttct gcatcgtcga tttcagcgat
     6661 actaataatc tgtaaaatca attcattcag tgataggtca ttgagaacaa aatttttata
     6721 aacaacttcg aaatcttttc ttaacagctc catgttctca ttggtataat ttctactgtt
     6781 gaacaaagaa aaaatataat agacatcttc ttcttgtaag tctagaattc ctttttgctc
     6841 ttccaatcct tgacagacta attgaaataa cggcttcgtt tctgcgcttt tcttatcttc
     6901 ttctttcagt ccaaggggaa atgcctttct tccgattgcg atctctattt ctcgtatgat
     6961 aaaggacttt tcatcttccg aatatcttct tttaaaaaaa tgagtctcta cataatcaat
     7021 caactcgtta caagcttctt ctacatacgg atttttattt tcatagcctt cccaattgac
     7081 ataacgtact aaagctagca agatgttccg cgagtcaaat tctgggataa tgatttcttt
     7141 atttttcaaa taatcatttt ctttaaaaaa atccaatacg atttttttga ttgtatatac
     7201 tttactcaaa gaaataaatt caagatcagc cagttctgta ctcgtgaata taccattaaa
     7261 ataataactt aaaaacttta aaaaataaga ttgaccgtac agaaactgtg tgagctcaga
     7321 aagagcaata ccatgtttga atacgagttt atacttatgc ttctctctta cttgttcttt
     7381 tatacaatat tctagacact cggctagact ttctagatcg tgaaggatcg ttggtgtagt
     7441 cacccttaga gaaatagctg tttgttcgat gtctatttct tggaattcaa ataattgttc
     7501 acacagatac acttttctaa atatatttcg ctcgatgtaa ttttccagca ttcctgatac
     7561 acgcctccag tttttcttat gattttattt aatcatatct gtaaatcgta tttttgtttc
     7621 ctttttattt agaaaagccc tttcaaaaac caataaaaaa agaaactggg acaaaagtca
     7681 aacaagctca caatttcagc ctcattgtag gtagctttga gccgtttgga cttttacccc
     7741 agcctctttc aagaatggtt attcaaagat gtcagcgtct agttctttga ctacatcttt
     7801 caacaattgg ataccagctg cgctgttacc aaatggatct agtgccgggc tgaagacacc
     7861 tatgccgtaa cgatttggca cagctgccat caacccgccg cctacaccgc tttttgcagg
     7921 tacaccaaca tggacggaaa actctcctga ttcatcatac aaaccagcag ttgtcataat
     7981 tgatttgacg attgtagcac tttcttcagt aatgatttgt ttgccattcc aaggagcaat
     8041 tcctttattt gccagcacag cagctaattt tgctatgcct gtagcggtga cattgaggga
     8101 gcattgtctg aaataagcat cgagtatctc cggtacgtct ccttcgatca tttgattacc
     8161 tttcatatag taagcaagag agcgattgat atcacctgtt cttgattcag aatgatagat
     8221 ttcttcattc aatgtgatat taggatcatc acagatctct ttcataaatg acaagattcg
     8281 ctcaaatttt tcatctgcat ctttaccggc aatcaacgag gttgttgcaa tcgctcctgc
     8341 attaacaaaa ggattcattg gatgtttgcg atgattgatt tccatattca tgatagaatt
     8401 gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag actttttcta ttccgttgtc
     8461 tttgattgct aataacaata cgggaacttt tgacatgctt tcgatggcaa agcgcacatc
     8521 ggcgtctcct ccctcaatca gttgttttgt atccaaatca taaatcgcca tacctaattg
     8581 tttgggatcc acttcagcta atgctggaat gtaatccgcc acttgtcctg tttgataata
     8641 gtggaaattt tttccaatca attgttctaa ttcttttact tccatttgaa taaccagctt
     8701 tcatttttta tttttctgca tgctggaatt tatgacggca tgcgtagatc gtaaatggaa
     8761 taactaagac gataagataa gaaacaatca gaatcgtttc ataaatccca tgctgtccag
     8821 ctgcgatact agcaggtgga acaaatgaga tacaaaaagc aaaaagtgaa gtcaaaagac
     8881 ctaaacaagc aacgattact tttacaactt ttccgcctgg aacctgatag gctctttcaa
     8941 gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa aaacataaag tacaacatca
     9001 ggtagattac aacagtcaat gacatcgctg caagaaatga aagattattc cccccgccgc
     9061 ttaatgtaaa gacggctgcc cagattgttg caacgatccc atttgcgatc atcaaatgag
     9121 caggaacacc gtgtgtgttt tcttttgcaa aatattcagg aagtaatcct tcttctgctg
     9181 ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc aatttctccg atgacaccta
     9241 aacaaacaag aatcgcaaga attttcgcaa tccatgcaag atttggatca atgtgtctta
     9301 ataggaattc taacgattga atcacccctg tattaagaga caaaccatgt tgaggtactg
     9361 tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat tgccagaata accaatacaa
     9421 acattgctaa tggataatcc tttttagggt tttccatttc atttgcatga ctggcagatg
     9481 tttctacgcc catatatgct aaaataaagg aaacaaaaac aaccagcgta ggcaatttcg
     9541 aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg tagtggagcg cctgaagcga
     9601 cataatggat ccctaagcca aacaagacta atgctggcaa caagatacca gctacaaaac
     9661 cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa ctgtgagagt aaaatagccc
     9721 agaaaataat caataggatt gccaatttca gatatttatt gttttgtata gcaccaatac
     9781 ccgttgcata ggataatgca ccagttaaga aatacagcat ggtcaagtag ccaactgtta
     9841 tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg ttttcccaat gtgcgactga
     9901 cccaagtata gacaccgcct ttttcccatc ctttcaccgt tgccatctct gctgcgcaca
     9961 atgccacagg gataaaccat agcaaaccgc ctaataacaa gaaaaatact aagctgaagc
    10021 ctgaggtcgc gaatgtggga tattcatata atgaaacgac cattgagatg gtcatagcca
    10081 aaaagccaaa gaacgttaat ttttttgcag gaattttcgt tttgctttgt tgcatgaatc
    10141 ttcctctttt ctatttgaat ttgtttcaat tgagtttgtt gccaaagaag aaaaagtcca
    10201 atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc gccgatttta
    10261 aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca atcacttgaa
    10321 tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat gcaaagatcc
    10381 ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca tcaagtgcat
    10441 catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata cccgcaatga
    10501 tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta atggctgcca
    10561 atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct tttacttttg
    10621 caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa ccaaatgcat
    10681 tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac cagccaaacc
    10741 aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt ctttctccta
    10801 aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat ccagctgtcg
    10861 tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa aatccgccac
    10921 cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata acaagtataa
    10981 tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga acggtaatca
    11041 cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca ccatgaaaca
    11101 tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt ccaataacac
    11161 cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata atcgttgtta
    11221 tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc cgtgctaatc
    11281 cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta cataaaatca
    11341 tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc tcctttctac
    11401 gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg aattaatact
    11461 tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct ttttcgtttt
    11521 tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg tttattttcg
    11581 tcttttttta tttttaaaga tattttttca taaggaataa agaatacttc atataaaata
    11641 tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa atttgttctt catttcaaca
    11701 taagtttttc ttcaatttgc ttataattta cgtgcaaaga atgaaacgac taatactaaa
    11761 atgattgcac cgatcaatga tggaatgata gccattcctg caattgttgg tccccaagtt
    11821 cctagtaaag cttgtccaat tgctgaacct actaaaccag caatgatgtt tgcgatgatc
    11881 cccattgatg atcctttatt cgtgattgct cctgcaattg ctccaatgat accgccgacg
    11941 attaatgccc aaataaatcc cattttaaat tcctcctaac tgacttctta cttcttattg
    12001 tacacgtggt tcgttatttt ctttgacttt ttgtgcacct ttgcctacag cagattttgc
    12061 tttatctgtt tggcgtgaag caaattgtcc tgtggatttt gctgcttctg ttactttgtc
    12121 ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg caacattcac
    12181 attcacttcg ataacatcta aatgtgtcat attgtttact tcagtactga tcaattcttt
    12241 gatttggttg taaatatctt cgatgtcttt accgtattct acgatcacat ctagatccac
    12301 agctacttgt ttcttaccta cttctgtatt gatacctgct gttacgttat ctgtgttgac
    12361 taatttttca gccatatttg agaaaaatcc gccatctaat gtcaatagac catctacatc
    12421 tttcaatgca taaccgatga ttttttggat gactttgtct tcataagtca attcaccatt
    12481 catcatgcgg ttttctcctt tttcatttgc caaaactgat ccatttgttg tattcatgtt
    12541 tttgttttcc atctttgttt cctcctatga tttaaaaaat tgatcaacta ttcctgactg
    12601 tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg attatgatca acaatgtctt
    12661 gaaaaatcca atcgttaacc ataaaacagc tagcagtagt ccaagacccc caaagataat
    12721 agggagcttg tatgctgaaa atagttcttt cattatttgg ccctcctatt ccactcgaga
    12781 gtgcttgtag tctcttgtat cttcttgttc ttcataaccg ctgtatgtga ctgccacttt
    12841 gaccgtttct tttgttccga gtactttagt tacttcttct tcgatatctt gcatcaatac
    12901 acctgttttc cctactaatg aagaagttcg tttcaagtct ccgttgacat ggatatggat
    12961 tcgatttttc gttgaacgta tccgtacttt aggtgaatga atgaactctt cttcgtgtaa
    13021 atgggaacgt accaaccctt cgatcgcttt tttgtcgatt gttagtttgc catcttcccg
    13081 tttcataacg aaagttcctc ttgactttgg atagaaaaga acgactagca agatgataat
    13141 agcaagaacg gcaaatacta cagctgccca gaaaatatat tgttgcatgt agtaattcgt
    13201 taaagtaaag aagcgaaatc gttccaattg ttcaggcata atatacggcg cattgatcaa
    13261 cgcaatcgct agaaatactg aaagtagcag taaactcatg ataacaccga ttatttttaa
    13321 ccccttattc attttccacc tcctataaac ttatttttac cctgtaaata actctaccga
    13381 caatcacagt atagatagcg aacagttagc atagcatcag taaataaagc gctaccaaac
    13441 attgctggat cataacggcg ttttattgcc agtctgatac tgaaataaca attgcttact
    13501 tattctctat ttacttttga ttgctggcta tacttaaagg atattattca agattaaaaa
    13561 ttgcaaagat tatgctcagt tattattaca agattctatt tatttattaa attttttcgg
    13621 agaattaaaa aatacaataa ataactttag ttactttaat gcgttcttac tttattttta
    13681 tattatcatt t
//
LOCUS       DACGDM010000068        13683 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.070, whole genome shotgun sequence.
ACCESSION   DACGDM010000068 DACGDM010000000
VERSION     DACGDM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.070"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            1..1404
                     /locus_tag="IXR05_002042"
     CDS             1..1404
                     /locus_tag="IXR05_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4260528.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            1753..2385
                     /locus_tag="IXR05_002043"
     CDS             1753..2385
                     /locus_tag="IXR05_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAQ4260529.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2973..4412
                     /locus_tag="IXR05_002044"
     CDS             2973..4412
                     /locus_tag="IXR05_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4260530.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4707..4925
                     /locus_tag="IXR05_002045"
                     /pseudo
     CDS             4707..4925
                     /locus_tag="IXR05_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5174..5389
                     /locus_tag="IXR05_002046"
     CDS             5174..5389
                     /locus_tag="IXR05_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260531.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5606..5862)
                     /locus_tag="IXR05_002047"
                     /pseudo
     CDS             complement(5606..5862)
                     /locus_tag="IXR05_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(6049..6960)
                     /locus_tag="IXR05_002048"
     CDS             complement(6049..6960)
                     /locus_tag="IXR05_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4260532.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6979..7983)
                     /locus_tag="IXR05_002049"
     CDS             complement(6979..7983)
                     /locus_tag="IXR05_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4260533.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7980..10103)
                     /locus_tag="IXR05_002050"
     CDS             complement(7980..10103)
                     /locus_tag="IXR05_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4260534.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10108..12555)
                     /locus_tag="IXR05_002051"
     CDS             complement(10108..12555)
                     /locus_tag="IXR05_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4260535.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12542..12931)
                     /locus_tag="IXR05_002052"
     CDS             complement(12542..12931)
                     /locus_tag="IXR05_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4260536.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12991..13494)
                     /locus_tag="IXR05_002053"
     CDS             complement(12991..13494)
                     /locus_tag="IXR05_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4260537.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13507..>13683)
                     /locus_tag="IXR05_002054"
     CDS             complement(13507..>13683)
                     /locus_tag="IXR05_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260538.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLSLFNRIVGA"
BASE COUNT         4204 a         2699 c         2501 g         4279 t
ORIGIN      
        1 atgaaaaaat ctttaaaact tgcatcagca gttatattaa tgtcccaact ccttatagca
       61 acacctttcc atgtgttggc aagcgaaaat tcaacataca aaattgcaaa agaaagaacc
      121 gagacgactg aaatgagtaa ttccgatgta acagcagaga gtagtgaact tttgacaact
      181 tcatcaagtg aaagtagtac gacttcaaat gccgagtctt caacaacttc atcaagtgaa
      241 agtagtacga cttcaaatgc cgagtcttca acaacttcgt caagtgaaag tagtacgatt
      301 tcaagtaccg aatcttcaac aacttcaagt agtacaagtg aaataacttc ttcgaaagtg
      361 acaaaaccaa accatataga atcttcaaaa aaggaagcgc caaaaacgga aggacaaaca
      421 aaaacttttt cgacaccaca gcaaatagaa tcaacagaat ctttccaatc acaaccaata
      481 ctatctggta atgaagaaat tcattttgac aaaaatgaat ctgtagaaaa ttttattatg
      541 aaaattggtg agtctgcgag aaaaattggt cagaaatatg atttatatgc ttctgttatg
      601 attgcacaag cgatcttaga atctgccagt ggtcaaagcc agttagctca ggcaccgaat
      661 tacaatttat ttgggataaa aggaacttat aatggaaact ttgtcattat ggtaacaaac
      721 gaagatttgg gtaatggaac gctttatacg acccaatcaa aatttagagt gtatgaaaac
      781 tatgaggaaa gctttgaaga ttatgccaaa ttattaacta agggaattag tggaaataaa
      841 gatttttatg caggagcatt aaaagctaat agtaaaacat atcgagaagc aactaaattc
      901 cttacaggac ggtatgcaac agatacacaa tactatttga agctaaatga attaattaaa
      961 acctacgatt taaccaacta tgataaagaa gttaaaggtc cacaaatgag taagactgga
     1021 taccaagtgc ctattcataa ttattcaata accagtttgt ttggaaatcg tggaaatgaa
     1081 tttcaccgag gacttgatat ggcagctaca cagggtgagc cgattcatgc agttaaagct
     1141 ggtaaggttg ttaaagcaga gtttcactac tcttggggaa attacgtggt gatacaacac
     1201 gaagatggat caaccgcgtt atatgctcac cagcaacaat acctagtaaa aactggagat
     1261 aatgttttgc aaggacaaat aattggctat gtaggaagta ctgggaatag tactggccca
     1321 caccttcatt tggaaatttg caaagatagt agtctttctc agagcatgtt agttgatccg
     1381 aaaaccttat tattcggaga ctaaaaaagg taatcaatct gacaaagtaa caagaaaatg
     1441 gttggattct tagacctttg atcaggatat tgagactgga attgatatct cgattacgat
     1501 gggtttgaca aataaaacaa gtccattatc gaatatcgag tgtattattg ccgtctttat
     1561 gctcatattt tgagcaggtt tcactagatg aaaacaattt atctatcttg aggatttcgt
     1621 gtacgtatcg ttcagtcttg tattgtaaat tagtcataaa atcagactaa gaaaaattgg
     1681 aaatattttt ttctgattta ttaaaagtta attgaaatta tatggtactt ctttcttggg
     1741 agggtaggtg cagtgaagga aagatatggt caccttactg ttgttgagga gattactcat
     1801 aatggatata aaaaatatcg ttgcctatgt gactgtggga atgaaacgat tgtatatcga
     1861 tcaaacttac tatcaggtag aaccaaaagt tgtggatgtg gaaattataa aaataggcat
     1921 aaatataaaa atttgacaaa taaaactttt ggtaagttag ttgcaatcaa gccaactaaa
     1981 ctgcgaagtg aaggaactgt tgtttgggaa tgtcaatgtc tgtgtgggag aaaaaagtta
     2041 gtatcggcaa agcgacttct aaaaggtgat gtaaaaagct gtggatgttt gaaatcaaaa
     2101 aagcatcaca ttgaaaataa aaaattcgga ttacttactg caaagtatcc tttggacaat
     2161 aactgttcat ggaaaacaaa atgggtttgt cattgtgagt gtggcagtat gtgtgagata
     2221 agttatagta acttattttt tggacatact caaagttgtg gatgtttaaa aaggcaagaa
     2281 acaaggacat gtgttgaagg gacagtaata gagtgtctaa cgtcaaaatt accgaaaaat
     2341 aatacaagtg gtgttaaggg agtttatcgt tctaaagaga aatagattgc gtatataact
     2401 ttaaaaaaaa agaggtacta tttaggatcg tatgattcta ttaagagtgc agctcaagct
     2461 agaaaagatg ctgaaaataa attgtttcaa cctttgattg acaaatatcg aggtaatcat
     2521 taattattgt ggataataat taacagtgat atataaacat ctataatata ttattcatac
     2581 tattgatatt tagtataatc ctatggaatt gaatatcata gcaatgtatt tgaaaagcaa
     2641 attggaaaac aaataggtgc aacaccataa atatgaaaaa attgggaaaa agtagaatgg
     2701 aaatttgctt acgtctcacg agatagctca cactattaat ctgaagaaca atgaagtcga
     2761 cttttagaaa ttgctagaag aaagtaaagc gaattatcac tagttactat agagtaagtt
     2821 caaataaagc atctccaact tacatggtta catgaggata tcaaatcgaa attactcaag
     2881 cttcctatgg ctagagtcgc gagaagttgt tgggcagtag acataggtta tattgttctt
     2941 agctacacga tcattagaaa ggaaatccta ttatgtatag ttatcaagaa gatgcaaaag
     3001 tccaaaaaaa tcgctggtgg attttgattg ctatatctat gtttaccttc atgtccacat
     3061 tggatggcag tattgtcaat attgcactac ctaccatctc agatgatatg ggcataccaa
     3121 tgaatcaagc ggaatgggta gtgtccgttt atctgatgat tgtctgttct tgtttgttgc
     3181 tgtttggtaa aattggcgat agccgtggga aaatcaaagt atttcggatt ggtacgctga
     3241 tctttgtctt gggatcgctg ttgtgtgggt tcaatcattc gctaggtatt ttattgttcg
     3301 cacgggtggt acaagccatt ggtgctagta tgactatggc tacaaatgcc ggaatcatca
     3361 cggaagtctt tcccatacat gaacgtggtc gggcattggg agcaataggt gcgtttgttt
     3421 cattaggctc gattgctgga ccaggtcttg gcggcttgat tttgtcccaa ttttcttggg
     3481 cgtacatttt ttggatcaat gtaccggtgg gaatcgtaac gatgttgatt gctgaaaaat
     3541 tcttaccaaa agatatcacc atgagcggcc atacaatcga tggagggggc tttgctgcca
     3601 ttgcggctac gattatcagc ttttttggag caatcttttt ggggcaagaa agtggctttt
     3661 tccatccagt cccccttgta ctgttcgtaa tttcagtgat tgcctttgtc agctttttaa
     3721 aagttgaaaa gaaagcagcc tctccattga tttctttcgg tatttttaag aacaagattt
     3781 ttaccatgag cttgattaca gccttgttga ttttttcttc caacttcttt gtcaatgtag
     3841 tgattccttt ttatctgcaa aatgctcgcg ggttgagtcc tagctatgct gggctgttga
     3901 tgatggtctt tcctttgatg atggtcgtcg gggcgccttt aagcggctac ctgaccgacc
     3961 gggttggccc ggagattttg gtattagtag gcttgggctt attgtcggta acccaggtca
     4021 tgtatatgtt tttgtcagtg gactctcctt tgtggctata cattgtcgct actgccatca
     4081 tgggtgccgg caatgccttg ttccagtccc ccaataatac gatggttatg agctcggtca
     4141 ctatcgaaaa cttgggactg gcaggctcga tgaattcctt tgcccgaaat ttggggatgg
     4201 tcagcgggat ttcgctttct acgacggtct tatatcaagc gatgtctgct aagatgggcc
     4261 agcaagtaac taactatatc gcaaatcggc cggatgtctt tttatatgga atgaagatta
     4321 cctttttagg cagctttgtt ttgtgttttg ttgccttttt cctgactatc tggcgtatca
     4381 aaaaacaagg aggtattcag aaaaatgtct gaaaaaacca ctgttgaaga atttttggag
     4441 gcctgcgtat gggtgagtgg gatttccatg gatgatggaa gatgaagtga acttctaaaa
     4501 gccgaaaaac tcaagtatta tcttcaaaat actagtgctc aatgagatgc ttgatttgat
     4561 cacaagaaga ctgcgaaagc cgctggcaac cgcaagctag gtatcccacc gatggactac
     4621 gttttagagg ctactggtta tgaatacgga gccaacgctc tcatctgcat aagaatacat
     4681 cacccagatt atgtaaagat tttcgatact tctgtcaaaa aatcattaag atagataaat
     4741 gatttccgtc tagtcaaatt ggttcagaat gtagacacac agatggtaag aagtcactca
     4801 caattcgaga atggacttgt cctatttgcc gtatacatca taatcgaaac gtcaacgata
     4861 gtatcaatat tttgaccaag ggctatgaat acaagcattg ccttagaaaa catcaagaac
     4921 cttaggaaca acggggatag cttggttaat aagagatacc gctgtttagg cttgcaagta
     4981 tactctttta tcaagaattc cgtggcttta gtcatgagag gcttaatact atgaaaattt
     5041 tctttagcat ttttgattta ggttcctttt ctaattataa taagatgacc actacagtaa
     5101 cctactgaaa tatataaaca gccactgtag taccattttc aaagtagtct atgagaggag
     5161 aatcttcatt cttatgaacg ctggaattgc ggatatgaat ttaataaaaa aaacccttaa
     5221 tgattttact tccaattcaa tatcaaaagg tactggtatc aatttaagca caataaaaaa
     5281 gctgaaaagt ggtgaaagat cagtggaaaa gctgaatctt ttagatgcta taaaaataac
     5341 ggaatttgct atgaaaaatg gaaaagctga gattgaaata tggagataat tatcgtctag
     5401 tgaattactt gccacttagc tgaatttaac gatccttggt gcttgaaggg ggagattctt
     5461 gggaatagag catacttgca agcctatgtc tttactaaca acgatatctc ttattaacca
     5521 agctatcccc gtagttctaa ggcttttact tttatctaag caataatcgt attcaaagga
     5581 aatttttgac ccttagaaag tctcatttta tcagacgtga gcttaggcat tgctgaattt
     5641 tgttaattcg gttttaggtt gtgctttgag cataatatga aagtattctt tatcacgatt
     5701 tcattcatct aaggtaatgt gatgtgattc tgaaattctt tcaaaggcag tttttgcata
     5761 agctgacatt acatcatcaa tgacatgttt acaatgtttc actactaaaa taagggggta
     5821 accaagaaga aaaactgaat gattatttgt atctaattcc atggtatatc aaccatttcc
     5881 tatatagact gattatgaca tggattaaaa taaaaaggca ctatgtctta attgtcggtt
     5941 ttcgagttac cgaatggcat tcatcaccca cctatagagg atgggcgact tctgcctgaa
     6001 ataagttaca ctacttataa cttctaataa aattagattg agtcattatt atttaacatc
     6061 aacgattttc cagtttccat ttttttgtaa tactaatttg tactgaaagt agctagtggt
     6121 ttttgataca ttatcaaggt attttatctt tgtactcact agaaaatttt ttccgttttg
     6181 tagataaact ggattctcta actccgaaaa ctttaagtca atattgattg gtcgcatcgc
     6241 accattttca acataatact ccaattcttt ttcagaagct gatggataaa gtttaaaaaa
     6301 tgtttctaaa aaatcggtga tttcttccgt tgttttggca tcaatttctg aatcgttttc
     6361 tacttgtttt gcttcatatt ttgccttgtc tggctttcca atcattgttg gcaaactagt
     6421 tactaaatga ttcctgtttt catcttcaaa gattgtcact cgatatgcag aagaaattga
     6481 ttgcgtcttt tttccctctg taatatgttg ctccactaaa aatgaaacga caaattcttc
     6541 cgagtgtttt tcaacatcta gaatttttac agattgaact tcggaactcg tgggaatatc
     6601 tgctcgaacc atatcttgga ttaaagcgag accgttttct gtaaggtact gttcgagatt
     6661 actcattctc ttttcaattg cttctttgtt atttttccat gaaaaatatt ctttcgcaaa
     6721 atcctctgta aaactttcaa cgccagaagt attcactacc ttctctttta taaccacttt
     6781 ttcatgagtt gtatgttgat caatggcggt gaaattttta taaacgccaa aagcaagact
     6841 acaagacaat aaaagccaaa gggcaagcac catttttcga tgcttaccca cggatacaac
     6901 tcgttctttt ttcttttttg ggctcttttc cttttgattc cgttcaattt ttatcttcat
     6961 tctttttcct cttttctctt atttgtatcg gccagctccg ataagatgct gccgccaata
     7021 gttttccgtt agattcgtcc accccactgg atctcctgca tgaaacatgc gattctcccc
     7081 tgcgtaaatg cccacatggg tcacataagt accggcatca taggttgaat gaaagaaaac
     7141 taaatcacct ggtttggcat cttttagatc aatatgagtc atggcatcat attgatcctg
     7201 agccacccga ggaagtttca ggtcaacttt ggcataacac cattgggtca agccactaca
     7261 atcaaacccc gtttctggac ttgagccacc aaacacatag gccgttcctt catacttaaa
     7321 tgcctcatca aaaatttctt ggactatttt gtcatcaaac tgagttgtag ttaggtattg
     7381 cttcactaat aaacagtaaa acatattgcc ataattatac cgccacccac cattttcctt
     7441 aatcgcgatt gggttggggt aatcgacttt ttgaccacct gatttttcct ttgaaaaaga
     7501 ttcagctaaa gcaaaactat gcttcttccc gtttttcccg acatgatcta gatacccgcc
     7561 accatagtta taggcctgaa taatactatc ttgatcacac cctagttctt tggaacgctt
     7621 aaccaaagac gcaaaataga gacagccttg tttgatggat gcctcggtac ttaatgaatt
     7681 aggtggtaat ccggctgact cagaactttg cataacgtct tccattgtgc caccagattc
     7741 cacttgaata atcgccaaaa gaattggaat atactctgtt atatccgatt ctttggcata
     7801 cttttccacc attgcacggt gtttcaatac ttcttctgag acactagttc cgccaggaga
     7861 agtgccagaa ctaccatttc cctcactgtc ttcaccaaac aacaaaccca cacacatcaa
     7921 aatacccata aaagagatgg tcagaaaagt taatgaaata acacccactt tcttcaagtt
     7981 cattttttct cacctgacct tgattttgga cgatggttca ttcttttttg tactttttga
     8041 ttggtctgct ttggcagagt ggacctctgt ttcacttgtt ggaaagaatt tttcttactt
     8101 gctgattggc ttttcccttt tgaaatgatt tcttgactag ttagttttcg tttgatttcg
     8161 ggattcagat ttgctctcac aatccgcttt ggtgcttctt ttttcagcat catatctttc
     8221 tgaggttgag ctgctttatc tattggaata ttcgcccttc tttttccctg acgatttgtt
     8281 gcttcactca gtatcttgcg tttttcgtcc attttcgcat ttcttcgttg tcgttgtttt
     8341 tctcgcaaat ccactcgatc cgctttttct tggaacagtc cgcgcttgaa ttcttctggt
     8401 gcttttttcg acttttcgat tcctttatgg agattgtatt tcaaattcgt tggcgtattc
     8461 cttacctgat cctttacttg tttagtctta tctttcacca aagcttgggt atccaaaact
     8521 ttgccgattt ttctcccagc caaattcatt cgggattgtt tcttattatt tgaaactgga
     8581 ttctccttag ttaagtcaga tagtatttcg tgatcgttcg gtaatcgtga attctttcgt
     8641 agagaagaac cggatggctt aaatttggat tttgattgtt cctttgccaa cttatttccg
     8701 actgctgcac caccaccaaa agccaaagct cgtcccacat ttcgattgag ttgccgcaat
     8761 tttcgattca ttaacatttg cggttttcgc atgacgcgtc ttcccattga ctggctatca
     8821 ttactctgga ggttgaacat actcataatg tcgcccaatt tgaaatagat accggcaaag
     8881 gtcacaattt gcagaaaagc aaccatgaaa aatggatagg ttgccgaaat attgaaaaac
     8941 atcgtggaga tgctaaatgc agtcgtaatc accaaagtaa cacccgctcg catcataatc
     9001 gtattgaata aacgaataat cgccttcttt cctaaacttt cataagtcgg caacatggac
     9061 aataagaaac taattggcag aaacatcgca aagataatga agagaatttg cgagaacaac
     9121 ataatccctg ttagaagaaa aacaaagaag gaaatgccaa tattgaacaa taccaaaaag
     9181 accacggtcc ctaaacggtt catggtcttg gtaatactga gattcgcatt gtcattgtct
     9241 tcaatctctg ccttgaccgc ttcttcccga tctttgcctt tgttttcatc tggactcaca
     9301 gatagaatct tgttgacccg gtcttcacca atttcttcta tgttggaatc atcaaattgc
     9361 agtagtaacc aaggttgttg gacttgaatc gaaaacaaac tatcccgaat caaatccaca
     9421 ctatcttttc cttggctttc tgaattgggt acaacgatct cggttccaag ggtaagggcc
     9481 gcttcactaa catctgagct aaagtcattg atttttgtga tataggtagg cgcataagca
     9541 atgaacgaac ccgatagtag aaaaatcatc acaaaattaa tcacggctcg aactgctttc
     9601 gtggtttctc gttttaataa tccggtatac gccacataca cccccagagc taaaatcatc
     9661 aataatagaa acccaaaata aaatccggag gtctggagtc cattttcagt aataccagcc
     9721 aatgtttgga tattctttcc aatactttca gccgtatccg aaatgaaatc taatttgtaa
     9781 gcctcttgaa ccacataacc cgtggcgttc gacaaataca aactcaccgt ccaaatgaaa
     9841 ttagtaatgg cataaagacc atacatcacg cttttcccta agccatcacc ccaattccaa
     9901 ggcaaccaat cccaagagct atccacaaag aaatctagtt gatagttgtt cagtgaatat
     9961 ttggaatata gatttcctgc ttcaactgta tcatcaacta gccctgtcgc ctcggctacc
    10021 gtaccaacta aactcaatag aactatcaga gtgagtatgc taataaaaac gattcccaca
    10081 atccgaaaaa gtttcttttt catcccctca ctccattctc tcttgaacag gtggacgggt
    10141 atcaaaggca tggaagagtt cttcaaagac tggatgtacc tgaaccacgc ctacccgacc
    10201 atacaaatcc tgcatcaagc attggccatt ttccaaatct cgtaggcgtt tttgattgct
    10261 ttcatcttct cgatccaagc caaagaattc caaggttttc ttgatttcat gaatatcggt
    10321 actgcgaaac gcaaacttca acccgatatt attcttcaag cgttcatcca gtaaatcatc
    10381 actattttgc gtgacaaagt aaaccccggc attcatagcc cgcccagcac gaacgagctt
    10441 attcgataat gttttccctt gcgctacttg aagaaaactc cacgcctcat ctaagtctac
    10501 aattttgaag atttctcgat tactatggat aaagtccaag gcaaaagtgg aaatgacgat
    10561 tagcatggaa acactaagca attccatggt ggtatattct tcaaaagtgg tttctgcatc
    10621 tggtaaaacc aaatccgcta cttgaatgat atttaactgc ctatctaaac taatcgactg
    10681 ggtaatcgaa ccatctgaga aaagcaaatg ggcaaaatca taatcggtaa aggactcgat
    10741 gtgatccgcg atattttccg caactggtga gccttctttt cgaagctcat taattacttg
    10801 taataatccc cgttgattgc tttgggtaac cgtccgaatg gccttacgca acactggaaa
    10861 cttctcccca tctcgactag aaattcctgt taaaaaggtc agaatatcaa ttgctagact
    10921 ttcagaatcc ttctttttct ccataatcac ataaggatca agtaatcctt gattttttgg
    10981 cttactagtt aagttgagaa tattgatttc atccgcaatt tctggcaagg tttctttcca
    11041 gccaccccgt tccccttttg gatcgacaat cacagcttgt ccaccaaaaa ggacggcgta
    11101 ataaactaag agattgttac taaaggactt tccgccaccg agtgaaccga ggaatgccgc
    11161 tgctagcgca ttggtaactg aatccttgac cccttgtgag gccaatgccg gtttcaggta
    11221 aacattgcgc cccgtatcta cgttataacc aaagtaaatg ccttccaact cccctaacat
    11281 ctgagtggcg ccaaaaccaa gtccggcgag aaaatcagac gtaacatact ggatataatc
    11341 attcatgtat cgcttactag aaggtaagaa ttcttcatgt agccccatca tatcgccaaa
    11401 aggccggact agttttacat tggtatcatc ataaaaatct agcacttcat cacaccggcg
    11461 ctttagttca tctactgatt cggcacttac tcgaaccaca tagctcagtt tgtacatgga
    11521 ttctttggac tgatccaagg tagtttccaa ttcatctacg gaatccaatg catctaagac
    11581 attggaattt gtttcattgt cagattgata ggcatggttg tccaagtctt ttaattcctt
    11641 tttcttattg cgaacggtag caagtgcctt tttgttcgtc acaatctcca cattcatact
    11701 agtgtcaatt gggaatgtaa attgttgttg ctggtaatag aaaagttctg aggagggaaa
    11761 ctccatttcc cccacaattg tattaattgt taagtacgct acatatgatt catgattctc
    11821 atgttccatg cataagtacc ggggcttttc ttcaatcaaa caacgactgg gacgtaataa
    11881 gtcgtaacgt ttcaccaaag tttccgactt cagctttttc tttggtagct gaaattcata
    11941 ttcttcaaat ggtgtaccct tttcgccata gatatgttca atcaaataca tcagatcact
    12001 cggtgtgact cgtctgactt taaatcttcg agccaattta ctttccatta gtttttcaag
    12061 cttggtatat cggcgaattt cttcattgga taaggaaaca aaatcgccca tcaaatgatg
    12121 attcactcca tagacaaatt cttgaaagcc ggagaagaaa gatttcttga gattctttag
    12181 attgacctct tcatctgtcg caatcagttt gaagccaata aaaaagcgat aatcaatctg
    12241 actatcgcca atcatggata ctaatgcctc tgtctgtaaa tcaattcgtt gtttcgctac
    12301 ttctgttaat cgcccggtaa tttccttttt tgatcgttct tgcgtggcac gaatactact
    12361 ttctgtggca atttgtaagg catgaatctt gccttcacga ttttgcgcaa tcaattgacg
    12421 aaagttatcg tggacttgat atttctgttc aggtgacaaa aaggagtaat tgtaaggtat
    12481 taactcatag taggcaaaac attctccctc ttgattaaag acaagattat tttcaatata
    12541 cttaatcggg tacatagttc acactcctta ccagagtaat gggttcgtcc catcgtttct
    12601 tctgttcttt gactttcttt cctgcgaaag tgaccttaaa tcgtaagtga tagctaataa
    12661 aagatcgtaa aaatcccaat ggtttcttac cgtcaaacgt tttttgcgac atgaaccaag
    12721 taactgccac cggtatacct aagtatttta aaaaggcccc ctctatcata gatagtggag
    12781 gcacatgggc aaatacgatg acaaacagca aggataaaac aaaccaagcc atctggttaa
    12841 aagtcacagg aaaaggcagt tgaaagtcat taattgcata aatgaccttt tcaactgccc
    12901 aaatactggt gtagcttttt attttcttca tcaaatcatt cctttaaaaa gaaggatagt
    12961 ttagaaatca actacccttc aataattttg ttaatatgga tactcaaaaa cacctcgact
    13021 cgttaccaaa taattgcctc caatctccaa gtctctacca cacgcatcaa aatcaatata
    13081 cgtcttcaag tgttctggta cttctccaaa atcaccagct tctacaatca agaaatatgc
    13141 tacatcactc atatcatcgc aatctggata atagataata tcatccacat gctctaccat
    13201 ctcctcaaaa gaattgaaga aagcatgttg aatctcagaa gcaacttcac caactggcgt
    13261 tccttcaagt tcctccgcta agccacacaa ccgattaatt tcctcaattg gcgtatactc
    13321 atcaatctca aagggaagtt cataatcatg aattgcatat tcctcgtatt cgtcatttaa
    13381 cccaattcgt tctttcactt catcaaaatc gacaggtggg gtaaaccacg cccccaccaa
    13441 ttcaccttcg ttatatttcc cgaggttcgc aatataaaca cgcatctgtt ccatcgtgct
    13501 tcccccttac gcaccgacaa ttcggttaaa caaactgagt aagacatcct tcaccccaga
    13561 agcattaaag accaatccga ccgcaatcaa agcaatcacc aaaaagccaa tcagtttgga
    13621 aaactcccgc ttaaatccta aaaacaaacc aatgaccaca attgccagta agactaagga
    13681 ttg
//
LOCUS       DACGDM010000069        13398 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.071, whole genome shotgun sequence.
ACCESSION   DACGDM010000069 DACGDM010000000
VERSION     DACGDM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.071"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(14..706)
                     /locus_tag="IXR05_002055"
     CDS             complement(14..706)
                     /locus_tag="IXR05_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4260539.1"
                     /translation="MQIELQHTHDKETFEKNYKVYFELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            791..967
                     /locus_tag="IXR05_002056"
                     /pseudo
     CDS             791..967
                     /locus_tag="IXR05_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1143..1712)
                     /locus_tag="IXR05_002057"
     CDS             complement(1143..1712)
                     /locus_tag="IXR05_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4260540.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="IXR05_002058"
     CDS             complement(1786..2109)
                     /locus_tag="IXR05_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260541.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="IXR05_002059"
     CDS             complement(2263..3075)
                     /locus_tag="IXR05_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260542.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="IXR05_002060"
     CDS             3429..4277
                     /locus_tag="IXR05_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAQ4260543.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="IXR05_002061"
     CDS             4422..5363
                     /locus_tag="IXR05_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAQ4260544.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGLPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="IXR05_002062"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="IXR05_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7636..9807)
                     /gene="copB"
                     /locus_tag="IXR05_002063"
     CDS             complement(7636..9807)
                     /gene="copB"
                     /locus_tag="IXR05_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAQ4260545.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(9827..12013)
                     /locus_tag="IXR05_002064"
     CDS             complement(9827..12013)
                     /locus_tag="IXR05_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAQ4260546.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12013..12222)
                     /gene="copZ"
                     /locus_tag="IXR05_002065"
     CDS             complement(12013..12222)
                     /gene="copZ"
                     /locus_tag="IXR05_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAQ4260547.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12235..12675)
                     /locus_tag="IXR05_002066"
     CDS             complement(12235..12675)
                     /locus_tag="IXR05_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAQ4260548.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12749..13288)
                     /locus_tag="IXR05_002067"
     CDS             complement(12749..13288)
                     /locus_tag="IXR05_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4260549.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3765 a         2807 c         2380 g         4446 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acccatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aaagtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtatgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt atgatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcagcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggtttg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaag
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag tcacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgggaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgga tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagttttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaatgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tggaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacctttttt cattattatc tgattttcaa tgtcaaagca tttagagcta caactaccgt
     7681 acttaacgac atcaagacag caccaactgc tggacttaat atgataccaa ttggcgcaag
     7741 aattccggct gctagcggaa ttgcaagaat attgtaacct gccccccacc agaggttctg
     7801 gatcattttc tttcgcgttt gcttggctag atcaagaaaa tgcaaaatat cttttggatc
     7861 gctgtttgtc aatacgacat ccgcagaatc gattgcgata tctgtccctg caccgattgc
     7921 catcccgatt gaagcacggg ctaaacttgg cgcatcattg atcccatcac ccaccatgat
     7981 tacttttttc ccttggtcaa ggtatttctg gacaacagct tctttatcat ctggtaataa
     8041 accgccataa tattcttcga tccctaaata atctgctact gcttgggcag cgtttttatt
     8101 gtcaccagta agcatgacag gagtgatttt tctttctttc aatgttcgga taaattcttt
     8161 tgcttctgtt tttactacgt cacctaaagc aacgattgca gctagatgat tttctaaaat
     8221 caggaagctg atggtatttc cttgttcttg gtaaggtttc aataatgctt gttctacgtt
     8281 taatccgaga cgctcaactt ctttttcatt aactattttc acttgttgtt ttttgactgt
     8341 tgcctctagc ccgactcctg aaagattttt tagattttca gcttgataag gcttgatttc
     8401 atgttctttc aaataattca taatgccaac agccaatgga tgattggcat tcgcttccaa
     8461 ggctcctaga tattgaagga tttcattttt attgaacgca tcatcaagta cttcgacacc
     8521 cgttacagta aattttcctt ctgttagtgt tcctgttttg tccagcatga tcacatctag
     8581 atcattggct tgctccagtg cattgcggtt tttcaaaagt aatccgtttt tagctgctat
     8641 tgatgtggaa cgagcaacaa ctaatgggat agctaaacct agagcatgag gacaggcgat
     8701 gataaagact gttaccatac gttctaatgc attaggaaga tctgtcaaga acaaccaggc
     8761 gatgaatgcc aggataccca caattaatgc gacataaaac agccattttg ccactttgtc
     8821 agataatgac tctagcttgg atttttctcc ttgtgctttt cgcaccattt ccataacctt
     8881 cgctagataa ccattttcac cagttccagt tacttcgatt tcgatcgttc catccccatt
     8941 gatagaaccg ccaatcactt tgtcattggc ttgttttttg attcctcttg attcgccagt
     9001 cacagctgat tcgtcaacaa ttgtttcacc tttcaagatt acaccatctg ttggcatttt
     9061 atcaccagac cggacgatca aacgatcacc ttcgtttact tctttcaatg aaactgtctc
     9121 ttcttttcca tctttcgtca agcgtttcac tgattctggc agtaattctg ctagtttttg
     9181 taaagcattg ctggcattcg acacagcatt catttcaatc cagtgaccta gtagcataat
     9241 aacgatcaaa gtagccaatt cccagaagaa atccatgacg tgtgtatgtg gattgagcag
     9301 atttgcgata aacgaataga cactataaat atatgcaact gtaatcccca tcgcgatcag
     9361 tgtcatcata gcaggacttt tttgtttcaa ttccatctta gctccactta aaaatggctg
     9421 accgccatag ataaatagta tagttgctaa gatcaatacg agccaatcag aaccaggaaa
     9481 cgttacttga aatggaaatt ccattcccat cattggtgaa aaaagaatga ttgggatagc
     9541 taggataagc gatagccaaa atttttgttt gaaattcccc atgtgcatgg aatgatccat
     9601 gccgccgtgt tcgtgatcca tgtgcatcga atggtccatt tgtttgctgt ttgctatatc
     9661 tccatggtta tgtcccatgt gcatggaatg atccatctga ctatggtcat gtttcatctc
     9721 catctgtttt tcatgagatt ctgtactttc tttgtttact acttcttttt tatgctcatg
     9781 ttttttctcc atatcgttcc cattcatttt tactccatcc cttctcttac tttttcatgt
     9841 gtcgatttaa gcacagggag ttcaacaata cactgacgga actaaacgcc atcgctcctc
     9901 ctgcaatgat tggattcaaa aagcctagtg cggcaaaagg aataccaatc gtattataga
     9961 caaaagccca gaaaagattt tgtttgattt ttctcaatgt caacctagac aactcgattg
    10021 tttgtgcaat ggatgccaaa ctgctattca tcagcgtcac atcggctgtt tccatcgcaa
    10081 tgtccgttcc acttcccatt gccataccga catcagctaa tgctaaggcc ggtgcatcat
    10141 tgattccatc gcctgccata ccgacttttt tgccatcttt ctgaagtttt tctacgtagg
    10201 ctgctttatc ctctggaagt acttcagcaa agatatgctt tggatcaata ccaacttgtt
    10261 taccaatcgt ttcggctgcc agtttgttgt ctcctgtcag cataaaaaca tctaatcctt
    10321 tattctggag ctgcttgatt gcttgtttga cttctagttt gatttgatca gccacggcaa
    10381 tcaacccgat cacttgcttt tcatcagcta aaaacatgac tgtttttccc tgctgttcta
    10441 attctaacgc gtgttcttgg tattcatcaa atgataggtt caattcaatt aatcgtttac
    10501 gtgtacccgc aaaatagcgt actccgttaa tcgtaccgct gattccagca cctgggtggg
    10561 ctgtaaaatc aatcatatcg tatgttgctg cttcttgcag ttttccgtat tccacgattg
    10621 ctttacctag tggatgttca gaagcttgtt ctaaagtata aaaaatagat aggacttctt
    10681 tagaaccgac tagatctgta actttgggct ttccttctgt aatcgttcca gttttatcca
    10741 aaacaatgct gtctaagtga gcagctgctt ctaatgcttc tccgccttta attaaaattc
    10801 catttcgtgc accaacaccc gttcctacca taatagctgt tggagtcgct aaacctaatg
    10861 cacatggaca cgcaatgact aatacagaga cactatggat caatgcgagt tgccaatcac
    10921 cagtgatcaa acctgtagct atgagcgtga taaacgcgat gactaatacg atcggaacaa
    10981 aaatccctga gatccgatct gcgatttttt ggattggggc tttgctccct tgagcatctt
    11041 ccaccatttg aatgatttgc gctaatactg tctgcttgcc gacttgtgta acttccatgt
    11101 gaagtagacc attcgtattg attgtcccgc caaagagcgt gtcatccgga ttcttttcta
    11161 caggaagatt ttcaccagta agcatacttt catctatcgc actgcttcct gaaataattc
    11221 gaccatctgc tggaatctgc tcaccaggac ggatgactag ttgatcacca acgactactt
    11281 cttcaatcgc taacgtttct tctttcccgt ttcttatcac ttgggcggtt tttgtttgaa
    11341 gagacatcaa ttgtttgatt gcattacctg ttttcgtttt tgctgtatgt tccaaatatt
    11401 tgccgagcaa aatcagcgtg atgatcatac tgctgctttc aaaataaaga tcttgggggt
    11461 gtccacggaa aaatccgttg taaatgctca atgcaaaggc agccgatgtt ccaattgcta
    11521 ccaatacatc catatttggt gctttcgtct tgattgcatg gtacgcacct ttataaaaac
    11581 gagcaccgac ataaaattgg acaggagcag acagcactaa ctggacgatt ggaaaatgaa
    11641 aaaagtgaac aatcgccgca tggcttccta acatcatagc aatcattgac aacatcaacg
    11701 gcaaagtcaa aaccgtactc aatataagat cgaatagcat ttttttcaaa tacgcttgct
    11761 tttcttctgc aattttttgt ttgtgggctt catcgtacaa aattgcacca tagccgatgt
    11821 tttctacgct ttggattaat ttttcagtgg tcgtcccttc atatttgaca cttgcttttt
    11881 cagtggccaa gttgactgtg gcattgacca caccaggttg tccgttcagc tctttttcga
    11941 tcctagcaga acaatttgca caagtcatac ctgtaatgac gaacgtatcc attttggttt
    12001 ctgctgttgc catcaaatca cctctgcttt ataacccaat ccattgattg cttgacaaat
    12061 cttttcggat tgaacttttg tttcatcaaa cttgaccgta ccgtttgctt ttttcaaatt
    12121 tactttcact ttttgcacgc cgtcaagtgc gcttactgtt tcttctactc ttgctgcaca
    12181 atgattgcag ctcatacctt cgattgaaaa ttgttgtttc attttttctt cctcctattg
    12241 atgttgttta cattcacatt gacctgggat acagttacat tcgatcgtat ctactggttg
    12301 cttttgttcc agttgtttca aaatctcatt gatatcttct tgagtcaaag tggcttcttc
    12361 tactagatcc gcaatcgtct ctccaatcct ttttgcacag atatgggaaa aaagattttc
    12421 cgtcgcactg cgaactgttt ccatctccga gacagctgga taataaatga atttttttcc
    12481 ttcttgttct gtccagatca cttctttttt taccaaacga cccagcaaag ttttgatcgt
    12541 tgctggtttc caatccatcg aatcagctaa gatctgcgtg atttcttggg ctgtcgtctg
    12601 tccaagtgtc caaataacac gcatgatctc ccactctgaa tcactgatct ttactggcgt
    12661 tttgactttt tccatttatt tcacaccttt cgtttacaaa tgtaatcatt atcttatgaa
    12721 tacagattac acttgtaaac aaaaactgtc aattattttt gctctctatt ttcaatttag
    12781 ttaaaaattc ttgtttctct cgtcttgttt taaggatgat cagtttattt cttgcattag
    12841 ctacttggat cagctgctgt attttcggtt cattgttttc ttcaaaatgc cagataaaag
    12901 ataaaaattc taagtattcc ctgtttagtt tctccgaaaa tgattcaggc atatctggcc
    12961 gagatttttt gtttatcttt ctttttagag aacgccaaac tactcggtag atggcgagat
    13021 aacgcggcac tttaagccaa atgatcttat ctgcttcttt aatcctttcc tctaatgtag
    13081 aagtataatt tccttcaacg atccatgacg gattagatac cataaacaat tgctgttctt
    13141 gcaaaaacca cttttttgcc tgaatactgt agtctgttgt atgccataaa aggtctagcg
    13201 gcagtagcgg aaagtcggtg atttctttga tcttccttgc gagggtcgat tttcccgacc
    13261 cactttgtcc aatcacgatg atcttcattc ttctccctca cttctctttg gaatttggtt
    13321 cgatcatacc acttataacg ccgcaaaaaa acaagggact gtgacaaaag tcgtgtcaaa
    13381 gtcccttgtt tcgaataa
//
LOCUS       DACGDM010000070        13351 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.072, whole genome shotgun sequence.
ACCESSION   DACGDM010000070 DACGDM010000000
VERSION     DACGDM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.072"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            2..169
                     /locus_tag="IXR05_002068"
     CDS             2..169
                     /locus_tag="IXR05_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAQ4260550.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(231..2042)
                     /locus_tag="IXR05_002069"
     CDS             complement(231..2042)
                     /locus_tag="IXR05_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAQ4260551.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(2039..2404)
                     /locus_tag="IXR05_002070"
     CDS             complement(2039..2404)
                     /locus_tag="IXR05_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAQ4260552.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2567..2962)
                     /locus_tag="IXR05_002071"
     CDS             complement(2567..2962)
                     /locus_tag="IXR05_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4260553.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(2980..3942)
                     /locus_tag="IXR05_002072"
     CDS             complement(2980..3942)
                     /locus_tag="IXR05_002072"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAQ4260554.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(3942..4154)
                     /locus_tag="IXR05_002073"
     CDS             complement(3942..4154)
                     /locus_tag="IXR05_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAQ4260555.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4175..4873)
                     /locus_tag="IXR05_002074"
     CDS             complement(4175..4873)
                     /locus_tag="IXR05_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAQ4260556.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4893..5435)
                     /locus_tag="IXR05_002075"
     CDS             complement(4893..5435)
                     /locus_tag="IXR05_002075"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAQ4260557.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5567..6571)
                     /locus_tag="IXR05_002076"
     CDS             complement(5567..6571)
                     /locus_tag="IXR05_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4260558.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6568..7557)
                     /locus_tag="IXR05_002077"
     CDS             complement(6568..7557)
                     /locus_tag="IXR05_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4260559.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7554..8360)
                     /locus_tag="IXR05_002078"
     CDS             complement(7554..8360)
                     /locus_tag="IXR05_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260560.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8526..9482
                     /locus_tag="IXR05_002079"
     CDS             8526..9482
                     /locus_tag="IXR05_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4260561.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9559..10077)
                     /locus_tag="IXR05_002080"
     CDS             complement(9559..10077)
                     /locus_tag="IXR05_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4260562.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10165..10314)
                     /gene="rpmG"
                     /locus_tag="IXR05_002081"
     CDS             complement(10165..10314)
                     /gene="rpmG"
                     /locus_tag="IXR05_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4260563.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            10542..10988
                     /locus_tag="IXR05_002082"
     CDS             10542..10988
                     /locus_tag="IXR05_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAQ4260564.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(11183..13078)
                     /gene="asnB"
                     /locus_tag="IXR05_002083"
     CDS             complement(11183..13078)
                     /gene="asnB"
                     /locus_tag="IXR05_002083"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAQ4260565.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         4158 a         2831 c         2277 g         4085 t
ORIGIN      
        1 aatgaaaaaa tttgtatctg gaatattagt aggaagtctg gcaacagccg ctgccgttgc
       61 tggtttggtt gcttctgtga aaaaaacagt gatcgatcca attgacgaaa aagaagcaat
      121 gatcgaagaa aaccgtaaaa aagcaatgcg taaacgcgtt tctcgttaat aattatttaa
      181 aaatacgcat gaagactttc taaaaaacag ataagtcatc atgcgtattt ttatttgtca
      241 gtcaatataa gttgtgctat tttatctgcc tgtctcagat tccatggatc tgtataaggt
      301 ctagctactg ctgcagttag ccaatccaca ccttcaacag gtattccata gcaataaaag
      361 tcagactgga tttcccctga agcatcaatc acgcgattcg tacctcgctc aacatctata
      421 gcttctgaat gataacttcc tgtattatct gaaaatgaaa aagggcgaac aagtttgttt
      481 tccttcaaat tttttatgac aggattactt gaacgagaaa agcttgtttg tggcaatcga
      541 gcttcaatca aatagcgact gctgatttct ttatcttgta gagaaataac atagcggttg
      601 tgcttttgct gaatatcaaa tggcggttcg atcaaatgaa aaatacccgc atctatcagt
      661 gctgctaatt ctttcgtccg aatgattggc ggaccgatcg ttaaaaagct atttagatga
      721 gtaaaccatc cccatagtat ttctttgtat tccttagcag aaaaaacgtg ccattcaata
      781 gcctgccgga ttggatcacg ccagtctttt aatgcatcaa atgttgaagc aaatgctcct
      841 gtgcaattgc ctttttccgc ttcttttatc tgcccttcaa taaatattcg gctagcttct
      901 gaaaagggct cattctgata ggcaagagga gtttctaaat acgaccaatc ccatctataa
      961 gggattagtg ctggatgctt tccgagacac tcctctgaag agagggagag aaaatcatgc
     1021 tcaaaatttt tctttggaat cggcaagtga tattcttcga tgattttctt gtaataaaac
     1081 aactcaacgt cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa tcccgactga
     1141 tgccattgct ccaggttttc ttttgttagt aaccgtggcc atgccattgc tccgccttgc
     1201 ttttgatttc ttcctcgagg gtaataaggg agcccccttc ttgatccact gtatacaatc
     1261 ggttccttgc ctgatggatg atagaccagt tttccctttt cgttctcgaa gcgccctcct
     1321 cttgatactg taaacaatcc gacataatca aaaaaactta agcctagacc tcttaaaaag
     1381 acattttctt taggcggtat cttcgaaaga tctacatctg caggattaga aggaagctga
     1441 tacagtaaaa catttttctt tgcgtagtct acccacactc tttcttcttc tgtctcatca
     1501 ttttcccagt gaccgcttgc taaaacaagc tgatcgatag aatagctttg ctgatctgtc
     1561 tgtaaaagat aaccatcttt tcttttgctt acttttttta ctaaagaata aacaaactga
     1621 atagaagctg gaaattcttc ttgcaacttt gagaaaaacc agcgttgata gagtccgtat
     1681 aaacatcgag tagattgctg atctttttcc agacgattga tttcttctat aattagttgc
     1741 ttatttttgg ttaccgtctg ttcgatataa tctgtagcag gtcctttact ccattgaaac
     1801 aagttgggtc cctgtgttac caatcctcca ctggacaatg tttcatctgt aaaaagcgtc
     1861 acttgttgag aaacagaatt cattaataac tccggtggct gattcaaccg ccaaactcga
     1921 cctccaggac cattgggatc gaaaagaaaa agttcaagag aatgtctgtc ctgattatta
     1981 tggagaatcc tttctgctac acttaatcct ctaggtccgg caccaatgat ccctattttc
     2041 atttgcatgc ctccatttcg ataaattttt tcaataaaac agcatggttc tgatgttcat
     2101 tttttgcacc ataaacaaaa gtaatgactg gatgttcttt cataagttga ctgagtttaa
     2161 aaatagcttg cttcttttct tcttcgaaaa tcaattcttg ctggtatttc tttgcaaatg
     2221 aagcaaatcg ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta ggtgcaattt
     2281 ctttcaacca cagatctaac tgcgcttttt cttttgaaat tcctcgtggc cagaatctat
     2341 ccacgagtat tctatagcca tcctcttttt cagcatcaag gtaaacacgt tttaatttga
     2401 tcatagttgt ttccttcttt ctaccttttc gcttagctta tatatgtaga taatagcaca
     2461 aaataaaaaa aatgaacggc acaactatcc attgcgccgt tcatgtgatc ttggtcaaaa
     2521 tctaatgatt gattcggttt ttaaagctgt catacaatca tctgttttat acttttttac
     2581 ttttgatttt tccagaccat ccgtcatatc cacccttaag taaataaatc tcttgataac
     2641 ctgctttacg taatttattt gctgtacgga tgctcaaact tttcttttga tcgtaaatat
     2701 agacaggctg gtcttttcga atagatccta atgaatcttt caaaacagtg taagggatgt
     2761 ttcttgcacc taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca tcgattactt
     2821 gtgcttttct cattccttct cgaaattctt cttctgtcaa agtcgttgct gaacgtttgg
     2881 ccattactcg tagatagact tcccaaagga tgattgcaag cacaatcaat agcaaaatga
     2941 tattaattac ccataaaacc atgtaatgcc tccgtttttt taagcaaatt tcaaggctaa
     3001 tgaggcagca ccaatgacac cagcttcatt accaagctct gctaatttga tttttgttga
     3061 ttctcttact tgcgggaaag taaattcttt aaaatatttc tctacacggc tacgtaaaaa
     3121 ttctcctgct gccgatactc ctccacctaa cacgatactt gacggattta atgtattccc
     3181 caagtttccg caagctaaac ctaagtagaa gcatacgcga tcaacaacca tcaatgcaaa
     3241 cggatcgtct tcttgagcca tttcaaagat atctttactt gttacttctt ctccgttgtc
     3301 tagcattgct ttcagttttg aatcccctgc gtattcttct gccaagaaac gacctaggcg
     3361 taccacacct gtagcgctag atacagtttc taaacatccg cgtttaccgc aagtacattc
     3421 gaacccttca ggatccacag tgatatgtcc gatttctcct ccagctccgc tcacgccgtg
     3481 aatcaaattt ccgccagcaa cgatacctcc gccaacacct gttcctagag taacgaatac
     3541 aacgtctgga tcgttttctc cagcaccttt ccatcgttca cctaaagcag caacattcgc
     3601 gtcattatcg atagcgaatt tgattcctgt tcctgcctcg atcagttttt tcacaaattg
     3661 aacttctgtc cagtttaagt tatacgcacc aataaccgtt ccagcttcgc tgtccacgct
     3721 tcctggggta cccatgccga ttccgataaa gtcttcggct ttcatattat ataaattcaa
     3781 acgatgattg attgattcaa tgatttcagg aacgatatgc ttaccatcat ccaaaatatt
     3841 ggtatcgatg ctccattttt gctgaatctc tccttctggt gttaaaattg caaattttgc
     3901 tgttgttcca cctaaatcaa tcccaataat cttcttgtcc attacaaatt tcctttcttt
     3961 cggctttctt caattcggtg ctctcttttt aatatgcgcc acgctgtcat gtatgtatca
     4021 tgatcaatca aacggctatc atacagatta cgcaattcga tagtcattaa ttcaatgtca
     4081 tagatgcgtg cacccacata gataaagatg ccaaattttt tgaacagctg ctgtacatca
     4141 tataagctct ccatctttaa gcacttcctt catattatac aagtaaacca tattttttta
     4201 aacccagtaa aatacatatt acaaaaagaa atacaaaaac tagtgtagaa agaatccttt
     4261 ggtgtatcga atagcttgtc tgttgtttcg gtagacccaa aacattccct aacactaatc
     4321 cgccaattag cccaccgaca tgtccccaaa catctacaga ggtatccaga agaccaaaaa
     4381 caaatgtcaa cacaataaat aaaagaaaat gtctgactag ctgctggatc gctgggttat
     4441 gtttaaaatg aaaccctaag ataaacaacg caccgaacaa accgaatatc gaagtacttg
     4501 caccaccaga cagaacattc gcttcgttaa aagcaaagct tgctgtattt cccattatcc
     4561 cgctgaacat ataaatcaag aaaaaacgcc aatggccata gattgcctcg atttgctgcc
     4621 ccataaaata cagtatcagt gagttcatta cgaaatgcat cagtccaaaa tggatgaaga
     4681 ttggtgtcac taaacgccac cattcattga agtgaacaag ataaggacca tacattccgg
     4741 cataataagg gatctcaagt cgcggaaata attccatcat gaggaagacc gctgtctgta
     4801 tccctaaaaa agcataggtc cataacggtc gtcttaacca tgcacgcaat tttatttgct
     4861 gttgataatt catgaaaacc tcccatttca ttttagtcaa taaacaattg ttggatcttc
     4921 tgatcaaagc tctccggttg ccattgttca ttcaattgtt cacgaaaaac aaggctacat
     4981 gtttttttat gaaaattatt taaataccgg tcgtaataac caccgccaaa accgattcga
     5041 taaccggctc tattgtagat aatacctggt acaatgagga gatcgatcat ctccggcaaa
     5101 tagagcttct ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag aacggactgt
     5161 tcatccattt cataaaacgc catctgacgt ttcggcaaag ttttaggtac aactattttc
     5221 ttttgttctt tttctgctcg ttggataacc ggctgtgtat ccagttcaaa ttcattcgat
     5281 aaagtcgtcc ctatcacttt tgctgacttc cagtactcgc tggcgaatag ctgtttatag
     5341 attcgctgtt ctttttcctt tttcttgcca cttttggcca gatttttcag cttttcgatt
     5401 cctttccggc gtaatcttac tttcaattgg tccaaaaact cacccttcct tctctcataa
     5461 aatggtatag gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc ataaatagaa
     5521 taaaaagaag acctagaaat gattggcctt ccttttttaa tgaatttcaa ctgttcagcg
     5581 cgtgtttttg tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa agggcaatca
     5641 aaattcctgt aggtacttcc ccacttggta gaatcactct agcaaccata tctgcactaa
     5701 gcagaaaaat ggaaccgaac aaaccgctca gaacaaaggt ccagttattt tctttacgta
     5761 cgactagctt cgcagcatga ggagctagta gtcctacaaa agataaacta cctgtcaccg
     5821 ctacactacc gcttgccaaa gcaacagcta acaacaaaag gattttttga cttttagcca
     5881 cgttaaggcc taatccttgc gcgcgttctt gaccaaatga tagcaataca atcctctgtg
     5941 cataaagtcc tcctagcgga attaagataa ccgcccatgg aagcaatgcc caaacataag
     6001 gccagctcgc accccagatt gatcccgcta accatgcatt cacaaatcca taattttcct
     6061 tagataattg gatcgtgcat agcaatgtta atgcagaaag gccggcatta acggcaatac
     6121 cggacaataa gattcgattc atacccaaaa agccatttcg atcataggcc gcaagataga
     6181 cacagcaagc agctaaaaca ccacctagaa aggctacaac tagcaataga aacggcagcg
     6241 aatagtgcga aaagaaacct aaataaagca tcactaaaaa tcctgctccg gcattaatgc
     6301 ccaatatact agaatctgcc aattcatttc ttgttactcc ttgcaagata taaccagaaa
     6361 cgccaagaca agctcctgct aataaactga tcagtaatcg aggaactcga aattctctaa
     6421 caatcagcgc caaagaagat gattctttcc ctatgaacgt ggcaaaaagc tgatccaggt
     6481 aaataaaagg cgtaccaatc attaaactac ctatagacag gatgacaagt acaaaaagca
     6541 agaaatagaa cgtccaatat atttttttca ccgttgttcc ctccttactt gtatcagtaa
     6601 aaacggaacg ccaatcaatg caatgactaa tccaaaaggt gtttcaaaag ggggattgat
     6661 catcctcgct gtaaaatccg ccaacataac caatccaccg ccaactaaaa aagagacagg
     6721 tagaacataa cgatagtccg ttccaaccat tccgcgaaca actggcggaa ccaacagccc
     6781 aataaatgaa acaggtccga ctaacgaaac ggcaatggct gctaacactg caactagaca
     6841 gaaaacaatc aaccgcgttc gtttaggatg acttccaaga gctaatgcat gtgtttcact
     6901 caaatgaatc aaagatattg cttttcctaa tgaaaaagaa accaaaacag caagtatata
     6961 taaaggaaac aatactgcta attgtttcca tgtgatattg gcagctccgc ctacaaacca
     7021 aaaagcaaga tcctgctgca gattaaagaa ttgggtaagt gcttggctga tagcagtaaa
     7081 aaaagaacta atagctacgc cagctaaaat cagctgtaaa ggattcatgc ccattttcga
     7141 aaactgcaaa aaaccaaata cgagcaaagt tacagcaaaa gaacctgcca atgacattag
     7201 aaacacagaa aaatcagaag ctttaggcca aaaagcaaaa ctaagggcca ttgccaacga
     7261 agcacccgcg ttgattccta gtaagcctga atctgctaaa ggatttcttg tcaccccttg
     7321 catcaatgca ccgctcaatg caaaacaact ccctacaaga aatgctcccg ccacacgagg
     7381 caaacgaata tttcgtatga tttggtgact ttgttttgat ctatcaaaat caaacaacgc
     7441 ctgccaaaaa tctgcttttt ccacagtcgc tgcgccattt gaaagagcaa caaaaaaaat
     7501 aatcaaaaga acaaaacaga ccaaaagcag gagtctattt ttcttcatag tcctcataat
     7561 tgatcctcct gctcttttgg caacaaatca taggttagaa aaactggttt atttgttctt
     7621 ggaagcgtga caatcgttgc atcaatctca aatatttttt tcatacactc ttttgtgatc
     7681 acttcttcag gtgtaccttc tgtgatcaac ttaccgtttt tcattgctaa taaataatct
     7741 gaaaaacgtg aagcatgatt aatgtcatga atcgacatca agatcgttgt ttgtttcatt
     7801 tgattgattt cagtcaataa ctgtaggatc tctaattggt gtgccggatc taaaaatgtt
     7861 gtcggttcat ccaagatcaa gatatctgtt tcctgagcaa gcgccatagc gatccagaca
     7921 cgctgggttt gtccaccaga cagcgttgcg atatcccgca tacgaaatcc agctagacct
     7981 gtagcatcca acgcccactc aattgcttca tgatcttgcg tgtccatgcc actgaacagt
     8041 ttttgataag ggtatcgtcc gtaagatact acttcttcta ctgtcatacc tgtagggtgt
     8101 tcactagttt gtgctaataa tgcaattttt tttgcaagtt cttttgaact gtatgtagag
     8161 atatcagagt tattgacaat gatctttcct gatttcacag gtagtatacg ggtaaaactt
     8221 ttcaataaag tagattttcc acttccattt ggcccaatca aactagtgat tttcccttca
     8281 ggaatcgtaa cagacatgtt ttcaatgatt tttttgtttt cgtagccggc tgcaatgtca
     8341 gctgctctta atctcgtcat ttcacccatc ctttcgctga aaatcattct caattatgac
     8401 gctgtttcaa catttcgtca agcgctactt tcatatctat agccaaatga agcggttgac
     8461 agcgttcgaa atatcaggaa taataaccaa tgagaaagat tctcaattat gttaggagga
     8521 aagaaatgaa attaaaaaca aaagtattca cattatctag catattgctg ctggctggag
     8581 tactgagcgc ttgctccccc tcttcagata aagaaacagc tacaactgcc aattcgacga
     8641 cttcatccaa tagtactcat acagtcacag atacacttgg acataaagta gagattccaa
     8701 acgcgcccaa acggatcatc ggcagttact tagaagacta tctgattgca ctaggggaaa
     8761 aacctatcgc ccagtggact gttggcagtg gttccattca agattatctg caagatgatt
     8821 taaaggatgt cccaacgatt tcttatgacc ttccttatga gaaagtgtta agctttgagc
     8881 ctgatttgct gttgatttct tcttccgcta ctgtcgaagg cgggaaatac gaacaatata
     8941 gcaaaatcgc gccaacttat gttgtaaaaa acggaacaga tgtcacatgg gaagaacaac
     9001 taaaagatgt cggcaaagct ttggcaaaag aaaaagaggc agaaaaaatc atttccgatt
     9061 atcaaaaatc catcaagaaa actcgagaag aactagcaga taaaatcgag aacaagacag
     9121 ctgcagtgtt gtgggtgacc aacaactcag cctttatggt cagcaaaaat cggtcaagtg
     9181 gaagaatcgt atacgacgat ctggaatttg gtgttcctga tctagtggaa gaggtctcca
     9241 aaaaagccac ttctgactgg tctgctgttt cctctgaaaa gctagctgaa ttagatgctg
     9301 actacatcat ccttgtgaac agtgacaaag atgctgccat gttcaatgaa ccaagctgga
     9361 agaatctaaa agcagtgaca gacaatcatg tactgcaatt cggacctgaa tctagttggc
     9421 tatataacgg acctattgcc agtcaggaaa tggtcaatga tatcaaagaa aaactaaatt
     9481 gattttaact aaaaaaagca tcttcacgat tagtcgtgag atgctttttt tcttattaac
     9541 aaactagacg catagatttt attcttcttt tgaagcaacc ctatttttta ctctttccca
     9601 tttttgaaaa cgatgggcat atagattttc ttgatccgtt atcccctcat actcctctat
     9661 aagggcgaag tctgaaaaat caatattccc aatatacgta tcgccttcaa acgtgctatc
     9721 gatcaatgtt cgccagatcc gaccagtgta aggaagaagt tcttgaaaaa tccgactacc
     9781 acccgaaaca tagatatctt ctgagatcgt ttgactatac gacaaaagtt catcgatcga
     9841 atgcattact tccgcatttt ctttcgtgcg aaaatttggt tgcgttgtca acacgatgat
     9901 atggcgataa ggaagtgaaa gatcccccat tccttcatag gtctttcttc ccatcactaa
     9961 aattcgatcc attgtatgtt cgcgaaagaa acgcatatca tttggcaatc gccatggtaa
    10021 caaaccattt ttgccgatca gaccattttt atcttgtgcc cacatggaaa taaacatatt
    10081 atccgctcct tatgatttta gatgttttga gataaaaaaa gtctcaattc tttgaccagc
    10141 aaggaattga gaactttaaa aacattattt tgtttcacgg tgcaaagtaa ctttgcgttc
    10201 gcgtgggcaa tatttttgtt tttccaaacg atcaggattg ttacgtttgt ttttgcttgt
    10261 tagatagtta cgttctttac aagaagtaca ctctaaagtg atgtttacgc gcatgttttt
    10321 ccctcccatt tttacaagaa tcctctaaga tgactctcag acttgattat cttaccatga
    10381 ttttttctag attgctagtg tttttcacga ttttgttaag taaaactact tgacgataaa
    10441 tacaacggtt ttacttctca aacaaaatct ttttcttttt gtataaatac ccttacactt
    10501 gtttatatag attatgtttt ttaataaagg gggatactaa tatgccatgg aacatgaagg
    10561 actttcctgc atcaatgaaa aacttagata aattgacaag aaaaaaagca atcgacatcg
    10621 caaatgcatt attagatgaa gggtaccctg ataaccgtgc gatcccaatt gccattgatc
    10681 aagcaaaaaa atggtatgaa gatgctagtg aatcagaaaa acgaactttc gaaaaagaaa
    10741 aaaatccaag caagacggat gaacacgata cgaatcctcg tgctggaaaa ctgcttgatt
    10801 cagatgtgat cgtagaatat gaggaagaac aatggatcgt gaaatctaaa ggggcaaaaa
    10861 aggcaagcaa ccattttgat acaaaaaaag aagcaatcga aaaaggaaag caagtagcac
    10921 aaaacaaaga atcaactttg ttcatttata aaaaagatgg gacaaaagaa aaagaaatcg
    10981 attattgaac atatgtaaag gggttgtgac gaaaatcgtg tcacaacccc cttatgttcg
    11041 aaacaatggt gttcctctgc caactccgaa ccataagtca taatatctat aaaacgggaa
    11101 gagctgtttt ttgaaattgt ttcttatcac tcagtgttaa acggtaggag aaaacctctt
    11161 ttttattgat atttgatttt catcaaacag tcacatagtc gattgcttct gcttgcggaa
    11221 tcgtttcatc tacaaagtag actttatacc atgtcaagaa actgaagatt gtccagattt
    11281 ttctttgctc ttctttacgt ccttcgtgat ggtcatctag caacttcatg attttttctt
    11341 gatcaaaaaa ttcttttgca aaatctgctt cgaataatgc tttgacttgt tcgtagccgt
    11401 gttcttcttt caaccaagct ttgattggca cagggaatcc taatttcaca cgattcgacc
    11461 attcttccgg aagatgtttg ttcgcagctt gtctgaaaat atcttttgtg ttgttttgat
    11521 tcaataaaaa cttacttggt atttgttgag ccaatttcat gacttcgata tccaataaag
    11581 gtactcggac ttccaaagaa cttgccatag aaagtttatc tgcctttaac aagatatctt
    11641 ttggcatcca ttgatgaaga tcgacatatt gcatcttatt gacttcatct ttgattcctt
    11701 ctgttttctc gtaatgaaca gtcatgattt catccacaga tggtgctgtt tgatattttg
    11761 gtgttaacac ttctgatgct tctgattctt cgaacactcg agcatgaccg ataaaatatt
    11821 cttttgcagg agcaagtgat tcatataaat ggatccgtcc atggaagttt ttcatttttc
    11881 cgattttacg tcctaaatta tagcgtgttc cttttggtaa ttttttcaat ccttgagcaa
    11941 tcacacggat gaattttgaa ttcgtatgga atccatacgt ttggtatccc gcaaacagtt
    12001 catccgcccc ttctccagat tggactaccc gcacactttg tgaagcaaga tttgctaaaa
    12061 agtacaaagg tacgcaagaa ggatttgaat caggttcatc taagtgatac tggatcaaag
    12121 ggaatgcttt gaacgacatg tctccgtcga tcactgctgc tgtattatct aagtccaata
    12181 gttcggttag ttttctggct tcaatcgctt cattataggt tttatcatca aacccgattg
    12241 agaaagaatg atctggtttc aatacagagg ttacataact ggaatcaacc ccgctggata
    12301 agaaagaacc aacttctaca tcactgaccg tatgtgcttc aatagaagct tgaacggttt
    12361 cgtcgatttt ttcgatccat tcttgtcggg aatgcgtttc ttttgtttca aaatctgcat
    12421 cccaatattg ctgaatgtct atttttccat ctttatacgt ataataatgg ccttcaggca
    12481 aacgatagac atctttgaag aatgtttcgc cgtttaatgg agaatattgg aaagtcatat
    12541 aaggtttcaa cgcttctttg ttcaattctt tgttaaaatc aggatgaggc agaaaacttt
    12601 tgatttctga accaaacata aatgttccgt tcatttctgc ataataatat ggtttgatcc
    12661 caaagtggtc tcttgcaccg aataactcat tcttttcatt atcccaaata gcaaaagcaa
    12721 acattccgcg gatcttttgc aataattctg ttccccattc ttcgtaacca tgcaaaagga
    12781 cttctgtatc tgcatgtgtt tgaaaaacgt ggccagctgc aatcaattct tctctcaaag
    12841 gctggtaatt atagatttcg ccattaaaaa taatgatctt tgtccgatct tcattgtaaa
    12901 taggctgagt accgccctct aagtcaataa tacttaatct tctgaatcct aaagcaacat
    12961 gtttatcgat atattctcct gaactattag gtccacggtg aacgattcga tccatcattg
    13021 tattaataat tgtttttttg ttgtccttgt cgttaacaaa acctacaata ccgcacattt
    13081 aactttcaca tcctaatata aaattactgt ttatttcatt catatgcatc ttatcataga
    13141 ataaatagcg gacgaatatt ttctctctta caatttcgtc acgtgaaaac aaaagatgaa
    13201 agtttctgtt tttacagaaa ataaagtccc aatatctaat ttaccatgtt ttcttttttg
    13261 aggctacctt attctcttcg tgttaaaaaa atattagtgg atgctatttc caaaaaaacc
    13321 agcaaaaaaa gacacgacct aaagatcgtg t
//
LOCUS       DACGDM010000071        13259 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.073, whole genome shotgun sequence.
ACCESSION   DACGDM010000071 DACGDM010000000
VERSION     DACGDM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.073"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            148..1887
                     /gene="yfcC"
                     /locus_tag="IXR05_002084"
     CDS             148..1887
                     /gene="yfcC"
                     /locus_tag="IXR05_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAQ4260566.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2044..3228
                     /gene="iadA"
                     /locus_tag="IXR05_002085"
     CDS             2044..3228
                     /gene="iadA"
                     /locus_tag="IXR05_002085"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAQ4260567.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3339..3542
                     /locus_tag="IXR05_002086"
     CDS             3339..3542
                     /locus_tag="IXR05_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4260568.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3643..4305)
                     /locus_tag="IXR05_002087"
     CDS             complement(3643..4305)
                     /locus_tag="IXR05_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260569.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4318..5820)
                     /locus_tag="IXR05_002088"
     CDS             complement(4318..5820)
                     /locus_tag="IXR05_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4260570.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6368..8047
                     /locus_tag="IXR05_002089"
     CDS             6368..8047
                     /locus_tag="IXR05_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4260571.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8174..8653
                     /locus_tag="IXR05_002090"
     CDS             8174..8653
                     /locus_tag="IXR05_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAQ4260572.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8872..9552
                     /locus_tag="IXR05_002091"
     CDS             8872..9552
                     /locus_tag="IXR05_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAQ4260573.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9560..10891
                     /locus_tag="IXR05_002092"
     CDS             9560..10891
                     /locus_tag="IXR05_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4260574.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10906..11868
                     /locus_tag="IXR05_002093"
     CDS             10906..11868
                     /locus_tag="IXR05_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAQ4260575.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11979..12317
                     /locus_tag="IXR05_002094"
     CDS             11979..12317
                     /locus_tag="IXR05_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAQ4260576.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12396..13103
                     /locus_tag="IXR05_002095"
     CDS             12396..13103
                     /locus_tag="IXR05_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAQ4260577.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4221 a         2338 c         2907 g         3793 t
ORIGIN      
        1 tcatacatag gagaaaaaaa acaaaataga aaaaagtgat tttctaataa attattcatg
       61 tggaaatgtc atttttactg tataattcat ttgattatcc attttttatt catcaaaatt
      121 actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa attcttcagg aaaaccgaaa
      181 cgcgacttca ctaaattatc gacaccccat acgtatgtca ttatttttgg tgtagtcatc
      241 tttgcatgga tactgacttt tgtcgttcca gcaggaaagt tcagcacgca agatattgaa
      301 tacaaagatg caaatggcga aacaagtact cgtactgttt tacgtcaaga ttccttccgt
      361 tatgcttacg agctggataa gtcgtatgtg tttgatcaat tagaagaact gcaagatcat
      421 ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat tggaaaaagt cattgctgac
      481 ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct ccttgacaga tgatgtgctt
      541 tacgatcagt acggcgaaaa tatctatgat acttctaaaa aattgcataa aacagccaaa
      601 atatggggaa cagatgattt tggcggcttt ggtttcttaa attttgtttt tgaaggacta
      661 gtatctggag ataagtatgg atctgctgta gggatcgctg cattgatcct tgttgttgga
      721 ggtgcttttg gtattattat gcgtaccgga gcgatcgacg caggtatcta tgcgtttatc
      781 agtaaaacta agggactgga gcgtttagct ttaccgctat tattctttgc tttttcattc
      841 ggtggcgcta cattcgggat ggcagaagag gtaattccat tctcaatggt gatggttcca
      901 tttgtcattg cgttaggata tgactcgatc gtagcagtaa ccgtgactta tgtcgcatct
      961 caagtcggaa atgcgacctc ttggatgagc ccgtttagcg tagcggtggc tcaagggatt
     1021 gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga ttatgtgggt agttgttact
     1081 gcattagccg ctggttatat gatgatatat gcagaaaaaa tccgtaaaaa accagaaagt
     1141 tcgttgactt acaaatcaga tgattatttc cgttctcata tcaaaaagac atctgatgaa
     1201 aataaaaaat tcatgcttgg gcataaattg atcttattag agatgttagt tgtccttgtc
     1261 tggatcgttt ggggcgtgac tcaaaaaggc tattacattc cagaaatcgc ttctcaattc
     1321 tttgtgatgg gattagttgc tggaatcatt gctgttcttt tcaaattaga tggaatgaaa
     1381 gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg atttagctgg tacagcaatc
     1441 gtagtaggta tggccaaagg gattcttctt gtcttgggag gatctgatgc atctgttcct
     1501 tcagctttga atacgatttt gcatgggatc gggacggcgt tgaccggtgt tccagctgtc
     1561 attggtgctt gggcgatgta catcttccaa agtttgttca acttggttgt tacatcaaat
     1621 tcaggacaag cagctttgac tatgccaatc atggctccac tggcagattt agtaggtgta
     1681 tccagacaag tagcagttct tgcttatcag cttggttcag gttttatgga cgcttttaca
     1741 cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac ggatcgaatg ggcaaaatgg
     1801 gcaagattcc aaatcaagat gcaaggattc ctgtttgttt taggaactat tttcatcatg
     1861 attgccattg caataggtct gcagtagtac tggagacctg taaataaaaa agtaatccaa
     1921 acagtagata aggactccaa gaaccgtcat tttacggtaa aatcaaagga gtaaagatcc
     1981 tatcgtttgg attatttttt aagatcctat catcagttat acttaaagaa agaggaaaaa
     2041 tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag attacttagg aaaaatggat
     2101 gtactgattg ccggtgggaa gattttggct gtagaagaac agctagaagg cggctacgaa
     2161 ggagtggaag tagaagaact ttcaggtgag ggaaaagtac taaccccggg tttcattgac
     2221 tgtcatttcc atattttagg tggaggagga gaaggcggtt atcaaaatcg aacgccagaa
     2281 gtcacattga gccaattgac tacagctggt gtaacgacag ttgtcggttg tttgggaaca
     2341 gacggagaag gtagagatat gactgcgttg atcagcaaag cgaaaggtct ggaagcagaa
     2401 ggaatctcca cttatgtata cgaaggttcg taccgattgc cggtaaaaac agtaacagat
     2461 tctatcatca aagacttttt gacaattgat aaaattatcg gaatcggaga aatcgcagta
     2521 tccgatcacc gttcttctca gccaagtttt gaagagttcg ctcgtgcagt agcagatgct
     2581 cgtgtaggag gcatgttatc cggaaaagct gggatcatca atgtccactt aggcggagga
     2641 aaaagaaagc tagagctatt gacacgaatc gtagaagaaa cagaaattcc gatcacacaa
     2701 tttttgccta ctcatgcaaa tcgcacacca gaattatttg aagcttgcgt ggcatttgcc
     2761 aaacgtggtg gcacgattga cttcactgct agcgaagatc ctgatttttg ggagaagaca
     2821 gatggtgaag ttcgcttcag caaagcactg aaacgattga tcgaggaaga tgtttcttta
     2881 gataatttca cgatgacctc agatggacaa ggaagcttgc cttattttga tgaaaacaat
     2941 catttcctag ggttaggagt aggaagtgcc aaggcattgc tagtagggat caaagaagct
     3001 gtgcaaaaag aaagtatccc tttggaaatc gccttacgag ctataaccag taatccagca
     3061 cgtatattga aattggataa aaaaggaaaa atcgaaattg gtgctgatgc agatctgtgt
     3121 atcttggata aagaaacgct tgatattgat acagttatcg ctaaaggaga aataatggtc
     3181 caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa gtttttaatc aacagctcta
     3241 actatctttt ttagaaaacg agcgttctgt ttgtctgtat ctgttgttga tgttaccctg
     3301 aaggtagatc aataaacaaa ctaagaggag gaagcacaat ggcagattta aaaggacgtt
     3361 ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga agcatacggc aaagcaacag
     3421 acgacaagag caaagaaaca gaagggaaag cacaatcact aggtgctgac atcaaagaaa
     3481 aagctcgaaa tttaggcgac gaagtcaaag acaagttttc tcgaaaagac gaaaaaaaat
     3541 aaaaaccact tattactaat tgaatcaagc aaataaaaaa tccgaaccat atctgcgaga
     3601 cagatatggt tcggattttt tatttgatca ttatcctgtt ttttaaactt cgattttttg
     3661 aaatttttta ttttttagtt caaagacttc atcacagctt tttgctactt caatctcatg
     3721 agtcacgatg ataatacagc gattttgttc atgggcgatt tcttggaaaa gtttgacgat
     3781 atcttgtgaa gttgtttcat ctagatttcc agtaggctca tccgctacga ttagttgatg
     3841 ttcacagcag atagcacgaa cgatagcgac tcgctgctgc tgacctcccg aaagtttggt
     3901 cacctgtttt tttgctaata tttcatcaat tcctacacga gccagtcgat ctaaagcaac
     3961 ttgtcgataa ttctcttgct tggtcttagt gatttccatt gctgctatga cgttgtctag
     4021 agccgataaa taaggaagca agttgtaagc ttggaaaata atcgagacat catttttacg
     4081 ataacttctt aacccgattt tgttcagtga acgatcttga tagtatacct ttccttcttt
     4141 tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt tttccagaac cacttgctcc
     4201 taaaatagcg tacatttttc cagcttcgaa attcagttct acatctttat aaagcgcatc
     4261 ttgcggatct tgataccaaa atcccaattg ttctgtccgt aacatcaaat tcctccttta
     4321 gtttaatagg atttttcttg ggtttaatct taatatccct atagaagcta aaaagacaga
     4381 aaacagactg attccaaatg ctactccggc taatagtccc aattgtgcag gtttgacatt
     4441 gatttccaat tcgctgactt gatcagaaac agcaaatgga ttattcgtgg ttccttgttg
     4501 accatcgcgt tgaccgcctt gttcttgtct gttacctggc atttgtccac cgccaggagc
     4561 ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt agctgctgtc ccacggcatt
     4621 cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca agaatcatac aaatagccac
     4681 ttcggtaaac aattggagaa tgattttact tctggattct cctaaagata gcaagacgcc
     4741 taactcatgc cgacgctccc gaatggtaat cataatgatc agagtaagta tgataatacc
     4801 ggctacagcc actagtaaaa caacattttt agaaaaactt gccacgttgt ttaaaggttc
     4861 caacattgac tgatacatgg aatcatttga ttgtaagcta aatgtatctg tgtcgatcag
     4921 cttctcagct tctttgagaa actcatccat tttatctgga tcagatagag tgtaaatagc
     4981 agaatctatc gtgttatcgt cagatgtccc atttagttca tttgcaaaag tgtaagaagt
     5041 gtaaagtgta ttcgacggat tcatgaagtt gaatttcata cccatactgc cgcttgtttc
     5101 gctggattca taaattcctt tgatcgtcat ttcataagtg gtatcttcat cttcagtact
     5161 cgtgattgtg aaagtatctc cgactgccag gtcatttgtt tctgctagag tagaatcaat
     5221 gactacattg tttgtgcctt tgtcgctgtc atctattcct tcaccatccg tgatttttgc
     5281 tgttccatca gaaaaattac tattttgtgc agttgctgac acaccactga tttgaaagtc
     5341 tgcttgagtc atttgcggat tcccgcccat tcctccagca ggttcaccgc ctgcatcagt
     5401 agtttctgaa ctgtcttcac ttgaatcaga actagtgatg gcagttattc catcttttgc
     5461 catagctgag gcggaacttt caaaggaata actctttaca ttatctaatt cagctatttt
     5521 ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg cctggatctg gacgttcttc
     5581 agtggtagaa ccgcttgaag aagtttgttc ctgtttttta aatgaagctt ctcgattggc
     5641 acttaaagtc actgttgctc caacttcttt ttgtgcttga ttcgctgctt cttctgcagc
     5701 gcttcgaatc gtgaggccag ctagcacaaa aataagaatg gctgtgaaca cggcaaacaa
     5761 taacaatgaa cgtccccatt ttacttttgt acttttccat gcacgtttca taaaattcat
     5821 attttgcatc cctcctagta gatgcatttg ataatagaca acctatctta aagctagctt
     5881 aaatcttatg ctgtttgcac accatcaaca tgaggttctg tatatataaa aagtcactat
     5941 agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt tcaaaccgac gaagaagaaa
     6001 tgaaagagga atagcaaaag aaatcctaga tgctacagag ggatttttac gtgcatagtt
     6061 gttctaacaa ttgctgatac tagcgattta gtttatttgt tgtataataa tggggaacag
     6121 ctgaatactt atataagtat tctggctata gcgtttcgca aaagatccat tttgttaatg
     6181 aagtatatcc aaaataaaat gcccatccaa ctgtcagaac gcggatgtgc tggtaatttt
     6241 cctgctgatt ctccataagt tgagaaatag tgattttgca tatgcttcat tggaatggct
     6301 catatattta gataaagaag aaaatcgaca tctttaaact tggatgtcat aagaagaggt
     6361 gaagtttgtg agtaccatta aaattatccc attaggcggc gttcgtgaaa atggaaaaaa
     6421 catgtatgtc gcagaagtgg gcgaggatat ttttatttta gattgtgggc taaaatatcc
     6481 tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat tttacgtatt tagaagaaaa
     6541 cattgatcgt gtagctggtg tctttttaac acatggacat gcagatgcga tcggggcact
     6601 tccttacttg ttgtcaaaaa tttctgtacc agtattcggg acagagttga cgatcgagtt
     6661 agcaaaattg aatgtcagtc gtaatgaagc agccaaagga tttaaggatt tccatgtggt
     6721 agatgagcat acagaaatag actttggtga aacagtagtg agctttttcc gtaccactca
     6781 tacgatacca gattcagtgg ggatcaatct gaaaacaaaa gaaggtagta tcgtttatac
     6841 gggagatttt aaatttgacc aaacggctat cccaatgtat caaacagatt atgcacgatt
     6901 ggcggaaatc ggcaaagaag gagtcttagc cttactaagt gaatcggcaa atgcagaaaa
     6961 tcctcagcct gtagcttctg aagcccaaat agcagatgaa gtatttgata cgatcaaata
     7021 ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat ttgcaacgag tgcaacaagt
     7081 attggatgca gcagaaaaag cacaacgaaa agttgtcttg actggtcaag atttcgaacg
     7141 aattattcgc acagcgatgc gtttagaaaa acttcaatta ccaagtgaag atctgcttgt
     7201 tacgttgaaa gacatgaaaa actatgatcc agaagaactg atcattttag aaactggccg
     7261 aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac ggtacacacc gtaatgtcaa
     7321 gattgaagaa ggagatttgg tttatatcac tactacgcca agcatcgcga tggaaaccat
     7381 cgtggcgaaa acggaagata tcatttatcg agctggtgga acagtgaagt tgatctctga
     7441 gaatatgcgc gtttctggcc atgccaatcc taatgacttg caattaatga tcaatttgat
     7501 gaaaccaaca tattttgtgc cagttcaagg agagtatcgt gaattagctg ctcatgcaga
     7561 tttggctcat gcagtaggga tgccatacaa aaatatctat attactggac gcggagacgt
     7621 gctggaatat aagaacaagc gtatgagtgt tgcaggaact acaagtgcag aaaatgtaat
     7681 gattgatgga ttaggcatag gtgatatcgg aaacattgtt ttacgtgatc gaaaaatctt
     7741 gtcagaagac gggattttcg tagcggttgt cactatcagt cggcgagaaa agaaaatcat
     7801 ttcaaaacct caaattactt cacggggatt cgtttacgta aaagctagcc gtgatctgat
     7861 gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa catttagaaa gcaatgattt
     7921 tgagtggagc aaattaaagc aagacatccg agatcaatta ggccgttact tatttgaaca
     7981 aacaaaacgc cgcccagtga tcttgccagt cattatggaa gctactcaac gtcgaaataa
     8041 aaaataaaca aaaagagtaa gatgaacctc tctatagagt gctcgtcttg ctcttttttt
     8101 gcgaaaaaca aataattttt gaatacagca tccctcgctt tataataaac gatagaataa
     8161 agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt tatttagaag aacaaaagat
     8221 cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa tctttcacag aagaactaca
     8281 aaaaagaggg attgatccag ctttgatatg taaaactctc gtagtgaaag gaaacaaaac
     8341 tggggtgatc atcgcattga ttcctttgaa cgatcactta gattacaaaa aaacgagaca
     8401 agtgacgaaa gatcgtaaag ttggttttcc tggaatggat tttgtattaa tgcatacagg
     8461 atatccccac ggagcaaaca cccctattgg aataaaactc gcacatcctg attattgttt
     8521 tttagcagac agttctttaa aagaaaaaga agaagtaatt gtgtcaagcg gtgaaatcgg
     8581 gagaagcctt cggataaaag tagccgattt agaaaagatc gtccatccta tttacgctga
     8641 tttaattagt taagggacga gaagagaagc taagcagagc agagacctca aacttgagat
     8701 tatatctgct tggtacttgg tgcatcctgt attatctgtt acaattgctt tgtacatact
     8761 gtactatcaa tccaatgaaa atatatttag cagctatatt ttttcattga tgtgcaagtg
     8821 atgaaatcgt ttttaataaa aaagatacag agaaaacgcg aggtgtaaaa tatgaaaatt
     8881 acgtatcatg gacattcctg tttaacaatt gaaatggaaa atggccaacg cgtgatgatt
     8941 gacccgttta ttacaggaaa tccattgaca gacttaactg cagaagaagt aaagacagat
     9001 tggttgctga ttactcatgg tcatagtgac cacataggag atatgattcc tattgcaaaa
     9061 gaaaatcaag ccacaattat cagtattgtt gagattgctg attatgcgaa cagcagagga
     9121 gtagattcat tcggtatgaa tatcggtgga aaacatgcgt ttccattcgg cgtggtaaaa
     9181 ttcgtacatg cacagcatag ttcaagctat gaagtagacg gtatcgttca gtatatgggc
     9241 gagcctagcg gaattattat tcaagcagaa ggaaaaacga tttatcatgc aggggatact
     9301 gcttatttca gtgatctagg attgcttgca gaagaattcg atattgatgt cgctttcttg
     9361 ccgattggcg ataactatac gatggggcca gaagatgcag caaaggctgc gcaaacaatt
     9421 cgtgccaaga aagtagttcc aatccattac aatactttcc ctgtcattga acaagatccc
     9481 gaatcttttg tagagttact ggaagatagt gaaggaaaaa taatgagcgt ctcggaaacg
     9541 ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg attttagaat atattgaaag
     9601 tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca aaagaattga atgtcagtga
     9661 aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc ggactagttt caacaattca
     9721 acgagtaggg accatccgta tcgaacgcaa attaaaaaaa catattgaac gtttgacatt
     9781 tggcgaggtc gtcaggatca ttgaagggga cgttttaggc ggggcggcag gattagacaa
     9841 ggtcttgaat aaattcgtca tcggcgcgat gactaaacat gccatggaac gctatattac
     9901 gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc caaaaattag cattggaaga
     9961 tggcgccgca gtattgatca caggaggatt caatacgact gctgagattg caaagctagc
    10021 tgatgatctt gaaatgccga tcttacgcac ctcttatgat acatttacag tcgcaaccat
    10081 gatcaaccga gcgttaagcg accaattgat caaaaaagat atcatgcttg tcagtgatat
    10141 ctatatgcca gctgaaaaga ctcattattt gcagcagaca gatacgattt ctgattatca
    10201 gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc gtcaaccgcc atcatcgttt
    10261 gatggggatt gttacggcaa aagatgtttt agggaaatcg ccaaaccaga tcatcgatcg
    10321 ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg agtattgcct ctgttagcca
    10381 tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt tccgatgact tgacattgga
    10441 aggcttgatt acccggcaag atgtaatgaa agcgatgcag cttgtccagc gacaaccgca
    10501 gattgcagat acgatttcgg atcagatatc tggaaatatc catacgattg atactgaccg
    10561 tgaaggaaat cgtttggaaa accctaagtt caaattcgta gtagcaccac aaatggtcaa
    10621 tggcgttgga accatttctt ttggcgtact tagcgaaatc atttctgatg tcgcacaaaa
    10681 aacaatggtg atgaaccaaa aacgaaatat cttgattgaa caagtgaacc tacattattt
    10741 gcggctgatc caattggaaa gcgaattaga cattcgtcca cgtgtattgg aaatcggcag
    10801 acgttccgct aaactggata tcgaagtgtt tattgaaaac accatcgttt ccaaagcaat
    10861 cgttgtttgt caagtaatgg aacgttctta gaaagcagga gtgaaatgac agtacagcaa
    10921 gaaatagtag atacaataaa aaaatacgat aaaatcatta tccacaggca tttgcgccct
    10981 gatcctgatg cattaggatc acaagtagga ttagccgaac tattacggga aagtttccca
    11041 gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc ttcgcttttt agcagaaatg
    11101 caagaagttg aagatgtctt ctaccaagga gcgctagtca tcgtgactga tacagctaat
    11161 tcacccagaa tcagtgatca aagatatcag ttggcagaaa aactgatcaa aatcgaccat
    11221 catcccaatg atgaccctta tggagatctt gtgtgggtaa atacaaaagc aagtagctgt
    11281 agtgagatga ttgcagaatt tgctttgatg tttcctgaat ctttaaagat gaacgttaag
    11341 gctgcacggt tactttatgc aggaatcgtc ggagatacag ggcgcttttt gtatccctcc
    11401 acgacgtccc gtacattaga gattgcttcg atattgagaa attatccatt tgatgcaagt
    11461 gctttgaaca gagagattga acaaatgccg atgaaagtcg ctaaactttc cggttatctt
    11521 tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa taatccttcc gcaagaaatt
    11581 cttgataaat atggaatcga tgattcagag acagcttcga tcgtttcact tcctggagtg
    11641 attgacgaag tgctggcttg ggggattttt gttcagcagc cttcagggta ttaccgcgta
    11701 cgtttacgtt ctaaggggcc gatcatcaat gaattggcta aacgccatca tggaggaggc
    11761 catccattag caagtggtgc gaatgcaaaa gatttagcag aagtagagga aatctataaa
    11821 gagatccaag atatatgcca atcgtataag agcagaaaaa cagaatgata cttcgttcga
    11881 aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt caagatcttc tttttccgtt
    11941 acaatagtgc tcactaaaga ttttaaagga gaaagaagat gacattacca aattgcccag
    12001 aatgtggctc agagtacaca tatgaagatc gaggcttgtt gatttgccca gaatgcggga
    12061 acgaatggaa caaagaagaa caagaaactg tcatagaaga cggattagtg gtattagatg
    12121 caaatggaaa ccgtctgtta gagggcgata gcgtgacagt gattaaagac ttgaaagtaa
    12181 aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa gaacatccgt ttagtagaag
    12241 gcgatcataa tatcgattgc aaggtagaag gatttggacc gatgaaactg aaatcggaat
    12301 ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca ttcttttcct actactaatg
    12361 ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta tggttatgga atgtatggtt
    12421 ttttagatcc gacatttctt ttggtcattc ttggattagt tatttccgga attgcgtcag
    12481 cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag aagcaaaaac aatgtgactg
    12541 gtacacaagc agcacaatat atattacaaa gtcaacagat aaataatgtc ggtgttcaac
    12601 aaattgccgg agatctcaca gataactaca attcaggtaa taagatgttg agtttgtctc
    12661 aagcaactgc acagtctact tcagttgctg cgataggtgt agcagctcat gaatgcggac
    12721 atgcggtaca agatgcttcg ggttatgtcc cattgaagat tcgtgcagca cttgttccag
    12781 cagctaactt tggttcgatg atttcgttcc ccttgattat ggtaggtgta ttgcttagct
    12841 ggaactctac gttaatcaat atcgggattt tcgctttttc tttagcatta cttttccaat
    12901 tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc aatccaaatt ttgagtgaag
    12961 gcggactact gacggaagaa gaagtaccga tggcaagaca cgtattattt gcagcagcac
    13021 tgacttatgt tgcagcagcg ctttcgacat tcctgcagct gttgcgcttg atcttattgt
    13081 tcggcggcaa ccgaagagat taaaataaag aagttgtgaa atcagcgctt tgatctgagc
    13141 taataccgag agttagctga ttgaatacca tttatttgga ataagggctc tttgtcaata
    13201 aggactgatg ggttgtacaa aatcaaatct gggtcagaat gaacctcatt ctggctcag
//
LOCUS       DACGDM010000072        13212 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.075, whole genome shotgun sequence.
ACCESSION   DACGDM010000072 DACGDM010000000
VERSION     DACGDM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.075"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            147..1016
                     /locus_tag="IXR05_002096"
     CDS             147..1016
                     /locus_tag="IXR05_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAQ4260578.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="IXR05_002097"
     CDS             1225..2250
                     /locus_tag="IXR05_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4260579.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="IXR05_002098"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="IXR05_002098"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAQ4260580.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            3333..5036
                     /locus_tag="IXR05_002099"
     CDS             3333..5036
                     /locus_tag="IXR05_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4260581.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="IXR05_002100"
     CDS             5038..7071
                     /locus_tag="IXR05_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4260582.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="IXR05_002101"
     CDS             7082..7522
                     /locus_tag="IXR05_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4260583.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="IXR05_002102"
     CDS             complement(7722..8849)
                     /locus_tag="IXR05_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4260584.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="IXR05_002103"
     CDS             complement(8852..9529)
                     /locus_tag="IXR05_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260585.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="IXR05_002104"
     CDS             9793..11559
                     /locus_tag="IXR05_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAQ4260586.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="IXR05_002105"
     CDS             11574..12011
                     /locus_tag="IXR05_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4260587.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="IXR05_002106"
     CDS             12024..13175
                     /locus_tag="IXR05_002106"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAQ4260588.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
BASE COUNT         4488 a         2293 c         2731 g         3700 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gactgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt atggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccacgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaaagtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg actaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcgaaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggaag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaaggg
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttggct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt tt
//
LOCUS       DACGDM010000073        13121 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.076, whole genome shotgun sequence.
ACCESSION   DACGDM010000073 DACGDM010000000
VERSION     DACGDM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.076"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            553..1086
                     /locus_tag="IXR05_002107"
     CDS             553..1086
                     /locus_tag="IXR05_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAQ4260589.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(1576..2100)
                     /locus_tag="IXR05_002108"
     CDS             complement(1576..2100)
                     /locus_tag="IXR05_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260590.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(2093..2566)
                     /gene="tsaE"
                     /locus_tag="IXR05_002109"
     CDS             complement(2093..2566)
                     /gene="tsaE"
                     /locus_tag="IXR05_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAQ4260591.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(2689..3669)
                     /gene="pta"
                     /locus_tag="IXR05_002110"
     CDS             complement(2689..3669)
                     /gene="pta"
                     /locus_tag="IXR05_002110"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAQ4260592.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(3822..4502)
                     /locus_tag="IXR05_002111"
     CDS             complement(3822..4502)
                     /locus_tag="IXR05_002111"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4260593.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            4628..5497
                     /locus_tag="IXR05_002112"
     CDS             4628..5497
                     /locus_tag="IXR05_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4260594.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            5523..6038
                     /locus_tag="IXR05_002113"
     CDS             5523..6038
                     /locus_tag="IXR05_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260595.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(6085..6648)
                     /locus_tag="IXR05_002114"
     CDS             complement(6085..6648)
                     /locus_tag="IXR05_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260596.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(6703..6882)
                     /locus_tag="IXR05_002115"
     CDS             complement(6703..6882)
                     /locus_tag="IXR05_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260597.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(6959..7468)
                     /locus_tag="IXR05_002116"
     CDS             complement(6959..7468)
                     /locus_tag="IXR05_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260598.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(7564..7944)
                     /locus_tag="IXR05_002117"
     CDS             complement(7564..7944)
                     /locus_tag="IXR05_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4260599.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            8274..9023
                     /locus_tag="IXR05_002118"
     CDS             8274..9023
                     /locus_tag="IXR05_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAQ4260600.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(9207..10484)
                     /locus_tag="IXR05_002119"
     CDS             complement(9207..10484)
                     /locus_tag="IXR05_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260601.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10563..11207)
                     /gene="pcp"
                     /locus_tag="IXR05_002120"
     CDS             complement(10563..11207)
                     /gene="pcp"
                     /locus_tag="IXR05_002120"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAQ4260602.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11406..12350)
                     /locus_tag="IXR05_002121"
     CDS             complement(11406..12350)
                     /locus_tag="IXR05_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAQ4260603.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12352..13038)
                     /locus_tag="IXR05_002122"
     CDS             complement(12352..13038)
                     /locus_tag="IXR05_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAQ4260604.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3792 a         2736 c         2329 g         4264 t
ORIGIN      
        1 ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttattaagag
       61 gttgtgaaaa agctgcactg catcaagtaa taagaacagc caaacaaaaa tagttcctca
      121 tatttttcgt ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattga
      181 gaagttgtga aatcagcgtc ctgacctgag tattagagaa acaaatggca aaatagttcc
      241 tcatattttg ctattttttg agctaatacc gagggtcagc tgattgaaca ccgtttagtg
      301 gagaagttgt gaaaaagtcg cctactttcg agtcgtaaga aatttttttg aaaatggttc
      361 ctcacaactt tgcataaatt tgacttaata ccgagaagtc atgatcccca tctaactcca
      421 aatcacaagg aatgagttca aaaactagct tttctcaaca aatattacat aaaaaattct
      481 atgttttttg ttaaatttat ttgctttttt caaaagtatg ttacagtaat ttcccaagga
      541 ggttttacag aaatgaattt tgttgccatg gattttgaaa ctgccaatca tcagccttat
      601 agtgcttgtt ctcttgcgct agtcatggta aaaaatagcc agatcgttga tgaattctat
      661 acattgatac agcctgagac tccttttttc tggcgaaatg tccaaattca cggaatccat
      721 caagaagacg tacgcaatgc gccgaaattc ccagaagtct ggcaaactat ccaaccatat
      781 tttcaaaaaa atcgtttagt cgttgcacat aatgctgctt ttgatacaaa ggtcttagcg
      841 ggatgcttag attattatca tcttgaacag cctaattatc tttctttatg tacagtgaaa
      901 agtagccgtc gcctgtttcc tgaatttcca aatcatcgat tgaacactgt gtgcgaaaat
      961 ttgaacatcc aattagatca tcaccatgat gcattggaag atagtcgtgc atgtgcggaa
     1021 atcctgcttt atcaagaaaa aaaattcggg acagatccat tgaaaaaact tgtgactata
     1081 aagtaaaaga atacttatga aacacacaaa gaggtcgtga gcctgccgtt tcactccgag
     1141 tcacaaggag caatttcaaa aaatagcttc tcatgtttat taaatattgt gactggtgac
     1201 cgaggagctg gcaggagaac accgtttatt ggagaggttg tgaaaaagct gttctgcatc
     1261 aagtaataag aacagccaaa caaaaatagc ttctcatatt tttcatttgg ttggacttat
     1321 taccgcagat gcaagctttt ggacaccgtt taccaagagg ttgtgaaatc agcgttttga
     1381 cctgagtatt agagaaacaa acggcaaaat agttcctcat attttgccgt tttttgagct
     1441 aataccgaag gtcagctgat tgaacaccgt ttattcaaaa aaaatggact gcgacacgac
     1501 ttttgtcaca gtcccttcgt gtgtttttct gccttctcaa aaggatgaca gtttctcact
     1561 cttttcctat ttcttctatt caatcaaata actcatttta tatacatcta aaaattcacc
     1621 tagatctgtt cttgcccctc taggcatgac cgcttcgatt tggaagccca tttttcggta
     1681 aaggtgtacg gctctttcat tacgaacttg aacgtcaagc tccaatcgaa aaagtacacc
     1741 catttccttc gcccaactga tgatttcttc tagcataaga gtgcctagtc ccattcccca
     1801 atattcctgc agaatactga taccgacttc tcccacgtga gacaaacgaa attgactgtc
     1861 tgccttgaca gatgctgttc caataatcgt cccttcatag attgcaagca gcaataaatt
     1921 attattgctt tcgtatatat aatccaactc ttcttctaag gtttctggtg gtaacaggag
     1981 ttctgcttca tccaaaacta aaaattctgt ctccttatta acttgtccca tcatcaaaag
     2041 aatgtctttt gcatctcctg gcactgcttc ccgcaagatg atcccaactt cttcactcat
     2101 gattttcagc ccatttttct agaattcgct gtttgaaggt ttcactttgc tccccgtatg
     2161 agattagttt cacataccgc ttttctaaat ctgtatcact tttttctaaa atcagttcca
     2221 aataatcctc cggcagtgct tcttctaata gatttcccca ttcaacaacg gaaagcccat
     2281 caccttcaaa atattcatct aaccctaaat ctgctccgct agctgctacc cgataaatat
     2341 ccatatgata caacggaatc cgaccttgac tatattctct aataatcgtg tatgtcggac
     2401 ttttgatcat ttgcgttatc cctaatcctt gggcaattcc tttcgtcaac gttgttttac
     2461 ccgcacctag atcaccagtc aatatcagat tgtcacctgg cattgcggaa tgaccaattg
     2521 cctctgcgaa ttgttctgtc attgttaatc ctgatagttc gatcattttt catcttctcc
     2581 cgctcttctt tctttttgcc agtatatcgc gtaatgaagt ttttttaaag aaaaaatgaa
     2641 ctagtcaaga acagcagctg ctgtttttgg ctagttcgcg tgtatttgtt aatcaatcaa
     2701 tgtttgtgct gctgtgataa tcgataattt atatacatct tcttcatttg ctccacgaga
     2761 caaatcagaa accggtttgt tcaagccttg tagaattggt ccgattgctt caaagttacc
     2821 gaaacgctga gcaattttat agccgatatt tcctgactgc aattctggaa atacaaagac
     2881 tgttgcttga ccagctactt ctgaatctgg cgctttcagt tgtgcaactg aaggaacata
     2941 agaagcatca aattgcaatt cgccgtcgat catgtattgt ggcgctagtt ttttagcgat
     3001 tttagttgct tcaactactt tgtctacttc tggcgatttc gctgagcctt ttgtcgagaa
     3061 gctcatcatt gctacttttg gttcgatatc gaacaattct gctgtttttg cagaatctac
     3121 ggcgatttca gccaattctt gcgcagttgg attcacgttg atcgcacaat ccgaaaagac
     3181 atatttttct tgatctcttc cacgtaccat gatcatcgct ccgcttgtcc gactgatgcc
     3241 aggctttgtt ttgatgatct gaagtgctgg gcgaacagtg tcgccagtcg aatggatcgc
     3301 tccagagacc attccgtctg caatccccat atacgtaagc atcgtaccaa agtaattcac
     3361 atcttttaaa atcttttctg cttgttcttt ggatgccttt ccatttctac gttcaacaaa
     3421 agtatccacc atttcatccc acttatcgta attatcaggg ctgatgatcg taaagctaga
     3481 tgttttgatt cctctggcat gcgctgcatt tcttatttct tcttcgttcc ctactaaaat
     3541 gggttccaca agttcttctg ctttcaaccg ggcagctgcg cctaaaatac gagcatcagt
     3601 agcttccggg aaaacgattt tgatcccacg gcgaacaatt ttaaatctta aactatcaaa
     3661 caattccaca agatgacctc cagacgtttt tatatgtatt atcatacact attccagaaa
     3721 aaaagaacag tttattttat ctgtatcagt caaaaatgct ggaaaaatta agtttttcac
     3781 atacaaagcg aactgcacta taacaggaaa gcgctgtttt attacactgt ttcaggcagt
     3841 tgccaatcaa tcggttcttc tcctaacgca aggagcgcat cattcgtttt cgagaagggt
     3901 ttggaaccaa aaaagccacg acttgcagat aacggactgg gatgtggaga tgttatgatg
     3961 atatggcgac tcttatcgat cattttgatt ttttcttgtg ccggttttcc ccacaagata
     4021 aacacgattg gtttttcccg ttcatttaat ttttcaatga tcgtgtctgt taatctttcc
     4081 caacctttcc cgcgatgaga atacgcttgc ccttcccgaa cggtaagaac ggtgttgagt
     4141 aaaaggactc cctgtttagc ccatgacact agatttccat gttgaacagg tgcgattcca
     4201 agatcatcat aaagctcttt atagatattt cttaacgatg gcgggatctt tacgccaggt
     4261 tgcacagaaa aagataagcc atgagcttga ttttctccat gataaggatc ttgtcctaaa
     4321 atcaccactt taacttcttc ataaggagtc aattccaatg cttcatagat atgatacata
     4381 tctggatgga tcttttggga cgcatattct ttttttaaaa attctcttag atgcagataa
     4441 taatcttttg aaaattctga ggacaaaact tcttgccaac tgttatgaat gatttctttc
     4501 aaaaactcca cctcctaata aaaagaataa ctcacatttt cttcaatcac aagggacaat
     4561 cttcaccctc agcacttgat taatatggta aactaggaac aagaagcaga aaggaacgat
     4621 aatcattatg atcaaattaa ttgcatcaga tatggacggc acattattag atgcccatat
     4681 gagtgtttct cctgaaaatg ccgaggcgat acgttttgca aatgatgccg gtgttgagtt
     4741 catggtcgct actggtcgaa actatcaaga agctcgcgca gctttagatg aggtaggaat
     4801 cgattgtgcg atgatcactt tgaacggggc acaggtattt gataaagaag gaaattcatt
     4861 gtttaccgtg tcgattccaa ataatcaagc aatctctgtt ttagatattc tagatgctaa
     4921 cggtatttac tatgaagtag caaccaacga tggtctttat tctgaaaatc aagcgaaacg
     4981 aattgaaagt tttgcttcca tggtggctac ccatttacct caccttacgt ataaaatggc
     5041 gattgccatg gcctcagcta agctggagtt attgcacatc acatacgtgg acagtattcg
     5101 tgctattttg gaagaaaaga atctggaagt tttaaaaatt atttgttttc atacagaagg
     5161 gccagctgta ttaggtccag ttggaaagca gatttctctt ttaggcgatc tagccgttac
     5221 ttcctctggt caaaacaata tcgaagtgaa ccataaaaac gctcaaaaag gaattgctgt
     5281 tgcccatgtc gctcacgagc gtgggatttc tttagaagaa gtcatgacga ttggcgataa
     5341 cttcaatgat gtcagcatgc tgcaagtagc aggagtcagt ttcgcaatgg gaaatgcaga
     5401 aatcgaagta aaagattatg ccaaatatac aacggacaca aaccttgaat ctggcgtagg
     5461 aaaagccata ttgcgcgcga ttgcagaaga cttgtagttt tatctagaaa agagggatat
     5521 agatgtcaga atttttcatt caggaaaagc agcttggacg tgcaactcgg acaattgtca
     5581 aaaacgaaaa aggacattcc ctgtttttga tggttggtcg ctggggaaca aagggcgatg
     5641 cattgtctct ttatgccatg aatggcgatc tcgttgctca catcaagcag ataagcctga
     5701 cattcggtac gcgttttgag ctgtataaag agttcgaaaa ggtgggaacc atgcagaaaa
     5761 tattcaattg gcccggtgac ttttattata ttcgtagact tcactggaca gtccaaggtg
     5821 atatctataa tcatcaatat caaatccatc atttcaatca gcaaatcatg aaaatggata
     5881 aagcaacact tttttcagga gattactatg tattggatgt ctcaaatgat gaagatgctc
     5941 cagtttgtat ttgtattgct gcggttttag attactggct ctaccgtaaa gacaaaagtc
     6001 gcgataagcc tgtttcttac cgacttaact taagttaaaa agatgtacct gaaatgcgga
     6061 aatacgcatt tcaggtacat ctttttagat attcttttgc atatgatcat aaagatgacc
     6121 actgatcatc cgctgaccga caactttgaa gtcatggcgt tcgtataatt ttttagcctt
     6181 tggatttttt tcatccacac ttagaccgat gacggagcga ttagctttct tcgccaattt
     6241 aggtaatgct tctaataatc gcgaaccgat gccttgtcct ctaaaatctt ctgatacact
     6301 gatagagtcc aaataccatt cgttgggaaa cgtttcttta tcaatgaaca aacgtgtaga
     6361 cgcatctagc tgatatttct ctaagatagg taccagtggc tgatcgatga ttgattcttc
     6421 ttcatctgta taaccgtaag caactcctgc aactttaccg tctatttctt ctacgatacc
     6481 tcgtgaataa ctgtaacgat aatttggatc agtgattgct tcttctaaaa tctctaaagt
     6541 cttttgttcc cctgtctgct tcaaaaatgg cagttccata tcttttagaa tcactaagat
     6601 caatggggcg atttctggag catcttcttt tctcgcaaaa cgaatcatag tttcctctcc
     6661 ttttctccat tctaacatgc agaaaaagaa atcgcaaaat cgttatttta aaaaatcttc
     6721 aatcttttca gtaatgaaat aaccatgagt aacgattctt gccgcttcag ttcggcaata
     6781 agggcagacg actggcattt ctttatcatt atgttcgact acattattga cttcttcgta
     6841 tgcaaatttt tttccgcaat tagggcattt cattttttcc atgttatctc aacttccttt
     6901 catctttact ctcttagctt actcttatat tgtaaaaaag agaagcaata tccttcttct
     6961 atgcagatat ccatacctga cggtcctgtt ctccatctat taatcggact ttataataag
     7021 gacgttcatc tttgactaga agtgtccact ctttcacttt tgcttttttc ccgtagtagc
     7081 tgactgcttc cttcatcgct gcttgcggtt gtttgaactc ttccgttttt tctatatcaa
     7141 aaagatgttc tgcggccttt tccgtgtcat ttcgtacggt tgttttccca gtggatggat
     7201 tgactgctat gacttgtcct tcacaaaaaa actggtattc atatgttgca ttcgtaggat
     7261 tctccaaatc tttttcaact gcaaaatgaa tagcagatat gttatgttct tttgtttcgt
     7321 tttttacgat tgctgctgct tttttcaatg agatccgata ttcctggtca ctaatatcat
     7381 ccatgtgaaa agcggcattg agcagtcccg tcataccggt aatccctatt acgatgaggg
     7441 cagcaacacc aaacatcatt tttttcattc ttcattctcc tgtttctttt ttttaaagaa
     7501 tatcaagaaa tgaacgaatg aaaaatcgaa tgaaacgaaa aaaaagtgac aattttgtta
     7561 tctttattcg tgcagttcta atggcaatcc gtctggatca aagaaaaacg tcattttttt
     7621 tcctgtaaag gtatcttctc taatcggttc tgattcgatc cctaaggact gcaattctgc
     7681 aattgtttct tcaatatcgt ctactttgaa agcaagatga cgcaagccac aagcttctgg
     7741 atagtttggt cgttgtggcg cattagcaat tccaaaaatc tccaattcag cacttcctag
     7801 tttcagatct aatttatagt catctcgttc tttgcggtaa ttttctctga ttacttcaaa
     7861 tcctaattta ttaacataaa aatcacgtga tttctgataa tctgaaacaa tgatggctat
     7921 atgatggatc gttgtaaggt tcatatgagc actcctattc ttcgtttaag ctcggatcta
     7981 tattaatctc cagttccatt gtaaatgtgt cagattgaaa aaaatagctg tttttccttt
     8041 ttataagaaa aaaggcaaaa aaaacagaaa gtaggtcctc caagacactc ttcctgttcc
     8101 caatataata aatgaaagta agaaattata ttttcaagaa aacaaacaga aaattatcat
     8161 aacacaaatt atttataatt gaaagactag ttttttttca agaaaagcat acaatagatt
     8221 gtgttagtaa atacagaaca cactacattt agtgtcttaa ggagtcctca tacatgaagt
     8281 catattttca gtttttagct catcagctaa aaggctggcc gcaacaaaat tattatcttt
     8341 tctttttcag tcttggctgc caggtcatga ctcttgtcaa tagtcccatc acttggctgt
     8401 ccgttattac atttatcggt accacgcttg gtgtattgtg tattttatcc atcaatgcgg
     8461 caaaatcagt caacggtatt ttaggtattt tgtctgcgat ttgttttatt atcgttgggt
     8521 tttcagcaaa gaactattta agtatcggtg aacagattgc ttatatgatc acattggata
     8581 tccccgtatt gttaagtaaa gaatggaatc ataatatggc ttcaaaaatc cgaaaattca
     8641 ctggaaaaag ctggtttatc gcaatcatca gtactttcct tgtctatctt gtttcaggat
     8701 tcctgattgg tcgttataca gatgatcctc ggccgtgggt agatgccatt gctttttcta
     8761 ttagcttgac tgctggtatc atcagtttct tgcgttacaa caaccaatat tactggtggt
     8821 tagcttcagg gcttgctcaa atggtccttt ggtatatttc atttacgcat ggatctgcaa
     8881 gtttggcgat gttcgtgaac agctctgttt acttgctgaa tgatgtcctt gcatttaccg
     8941 tttcaccttg gtataaccaa aaagaacgtg aacgtatgca aaaaatggaa gaagaatact
     9001 acaacgcaca acaacacgca taaaaaaact gagcgtggga caaaagtaaa gaacactttt
     9061 gtctcacgct ctaaacacgt ataaacggcg gaatcagaag caactccttc ggaaataagc
     9121 tgaaattcac aaaaatttga aaagcaattt tcgtgaattt cttcttattt cttggagtta
     9181 aacgcttctg tcccagcctc tattttttat agtaattcct tcagatactt tcttgcctca
     9241 tcattgaaac gcagtgattc ttctaacttc tgataatatt ccaacgcttg tttctgagct
     9301 tcagtaaaac gataatgttt tcctttccat ttgtcgattg tctcttgcac atttccagat
     9361 tggatatctt tcactactag ttgccatttt tcttttgaga ctgtacggtc tttcttatca
     9421 gcagattgta tagcttctcg ttctttacgc aatactttta aaaaaccatt tctgactatc
     9481 cgaggaatgc tgtcgaagaa cccttctgta aaaccatagc gacaatattg cttccaaata
     9541 aatagataga tttttggttg gatgaatcgt tggtttttcg caaaatattc catctgagca
     9601 gtgacttctg gtgttcgttg acgttttgtc tttctcaaca cggaaataaa tgtttcaaaa
     9661 taagcattag gatgtactgg cacttcttca tatacgatgg attgccaatc tttacgtaaa
     9721 aatgcgcgat agttgatcaa gaattcttct acatccttta ctaattcttc tgcaaagtcg
     9781 tcaaatagtt ctttttttat ctgtcgcttt tttgactgcc cattgatgtg ttcacttatt
     9841 ttcttgattt cattttccaa tgcttgataa tccgctatgt aaatcggcat ttctacttgg
     9901 cgaaattctg cgagccgctg agctaatttt atatccggta aatatggctg tttcatccga
     9961 cgattttggt acaagacaaa acagtatttt tgccatagtc cttcaggaaa atcgatattc
    10021 ttctgcttaa gccataataa ttcgtctaag gccagatcaa cttttgtcat tccctgatgg
    10081 atcgaagctg ccactgtcgg agagacatgc aggtgatcgg caaagtggtt gatgcctagt
    10141 tttaggatct ttccggtttt tggcgattta acgatgtatt gcacttttaa ttctctacca
    10201 cactcacaat acaatttttg ctggcttcgt tttgttcgaa aaaacggatt gatcttgaag
    10261 tcagaaaaca cccaatctgt tgcagctaaa taatgttctt ccataaaacg agagctgatt
    10321 agatatcggc ggtgcttatc gactagttcc cgctgttttt tcgttaattt tgcatagatc
    10381 tcccaacgtt gactgcttgt gtattgttta gaaattttga tgggatagct tttgctgatt
    10441 tcttttggaa accattcttc aaagacggat tgccattctt ccacggctgt ttctttcctt
    10501 tctaattaca aaaagctggc tactaacata acgttagcaa ccagccagtg tttcttgcta
    10561 aattagtgag ttgttccggc atttccggaa atatcttctt tattttctac tgctgcttca
    10621 actgcataag tcaaagaaga agcaatgtct tctaaagaca tagaaggcgt acccactgga
    10681 cgatcgatca cttgatcggg tgagaatggc acgtggatga acccacctcg aattgccggg
    10741 aattgtgttt cgatcaaatg aagcaaacga tacatgatat cattgcagac aaatgttcct
    10801 gctgtataag agatgtacgc tggtagacca tgatcttgta cattttttgt cattgctttg
    10861 attggcaatg aggtaaagta agcggctgga ccgttttctt ctaaagccgt atcgaatggc
    10921 tgatttcctt cattatcagg gattcttgct tctgctagat tgattgcgac acgttcgaac
    10981 gagactgctg accgcccacc tgcttgtccg acacagatca cgacatctgg ttggtgctgt
    11041 tggatggctt ctttgactac ttgactgctt ttttcgaata cggtcggtac ttccactttg
    11101 atgatttcag caccgctgat ttcatctggc atttttttta ctgcttcata ggctggattc
    11161 actttgtccc caccaaatgg atcaaaacct gttactagta ctttcatctg ttgttcctcc
    11221 gtccgattga tttaacatat ggttatcttt tatcatacca ttttccttga acagcgtaaa
    11281 taaaggaaac aatagtttaa ataacataac agatcaaact taatatattc ttataaaaaa
    11341 atagtgttcc actacaatgt tagaagaggt tgcgacaatt attctgtcac aacccctctc
    11401 ttctattatt taaatagaat catataagca atttggaaaa ctagcataaa taacgcaata
    11461 aacaactggt ttttgatcac tccgtatttg tctttcatct ccagcatcgc tacaggcacg
    11521 atattgaagt tagcagccat cggtgtcagc agggtcccac aaaaaccgca agtcaatgca
    11581 accattccta ttaacgctgg attcgctcca tgactaaata cgaatggtgc accgatccca
    11641 accgtcatca cggtgatggc cgcaaatgca ttccccatga ttaccgtaaa tatcaccatg
    11701 ccaagagcgt aaatgatgat gccgatgttc acatttcctt ctggaacgat cgtacctact
    11761 gcattggaaa tcactgtccc aactccagcg cttgtaaata ccgcacctag agaagctaaa
    11821 agcattggca acatgcttaa cggccctact gtgcccagca tatctgctgc atcatctaaa
    11881 aatgtacttg gtcgattatc tcgagaaaag aacatcaaga ttagcatggc tgcaaaaaca
    11941 ccgacgccca cgccgactaa agcacctaaa ttggtaaata gagcaaacaa gatcgcaaag
    12001 acaccgatac tcaaagctgg aataaaaatt ttcattccta gtttgtctga cattttttcc
    12061 atatattctt ttgatggaag ccggctttct cctttgctga ctttcttagc aattgctggt
    12121 atggtcatcg caaagatcaa gccaccgttc acgattgccg gaagccatct tcctcctgca
    12181 ataactaccc ctaagaccgt ccagaaaaag gctgacccat aacgatgagg attggtttta
    12241 tctgttaaat ttcttactcc agtgtaaatc aatacgagtc ccatcacgat ataaaggatc
    12301 tccagtaatt tatcgcctaa taaaatatca ggatttgtaa aaaagtccat cttattgccc
    12361 ctttcctgga taatatttct tcgctaattt cttttcttta agatagaagt agacacttgc
    12421 cacaactaaa gccgtgatag ccactggaac ttccactaaa gcaagctgtc ccaatgttac
    12481 gtcatatcct agatctttca gtgttgattg gactagcaac gcccctgctc ctccgatgaa
    12541 tagtacttgg ccaaagaacc agcagacatt ttccatagct gaagccatac cttttagttc
    12601 ttcttcatgc ttaggatgga cttctaaccc ttttgattcg atggtcccca atgccatcgg
    12661 taaaatgatt ggacgaacaa atccagcaac tccaccaaaa ctcacgttaa aagccgcaaa
    12721 gatcattcga aagatcccat aaatatctac aatcatacca gcagatactt tcttgaatcg
    12781 cttgatcaag gaagccgctg attctttcag accatttctt tcaagcgttc ctgttgccaa
    12841 cataatgatg ataaaaatcg ccatcccgcg attgtttaca aaacttgtac ctaaaagttc
    12901 taacattcct tgaatgccaa gaccgccagt caaagctgta acaactaaag caaccattac
    12961 gatcaatatc gagtctaatt taaatgcaaa cccgagaata acaatcaaga cgcctaaaag
    13021 gctaagataa ttttccatat attttcctcc ataaaatgac aatatttttt taattataaa
    13081 gcaaaacaca taaaaaatat agttgttttc tcacgaaata g
//
LOCUS       DACGDM010000074        13016 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.078, whole genome shotgun sequence.
ACCESSION   DACGDM010000074 DACGDM010000000
VERSION     DACGDM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.078"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            290..496
                     /locus_tag="IXR05_002123"
     CDS             290..496
                     /locus_tag="IXR05_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAQ4260605.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(698..1699)
                     /locus_tag="IXR05_002124"
     CDS             complement(698..1699)
                     /locus_tag="IXR05_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4260606.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1704..3617)
                     /locus_tag="IXR05_002125"
     CDS             complement(1704..3617)
                     /locus_tag="IXR05_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4260607.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3785..4291)
                     /locus_tag="IXR05_002126"
     CDS             complement(3785..4291)
                     /locus_tag="IXR05_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4260608.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4451..4891
                     /locus_tag="IXR05_002127"
     CDS             4451..4891
                     /locus_tag="IXR05_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4260609.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            5050..6390
                     /locus_tag="IXR05_002128"
     CDS             5050..6390
                     /locus_tag="IXR05_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4260610.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(6459..7616)
                     /locus_tag="IXR05_002129"
     CDS             complement(6459..7616)
                     /locus_tag="IXR05_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260611.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(7619..7975)
                     /locus_tag="IXR05_002130"
     CDS             complement(7619..7975)
                     /locus_tag="IXR05_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260612.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(8273..9247)
                     /gene="sgrA"
                     /locus_tag="IXR05_002131"
     CDS             complement(8273..9247)
                     /gene="sgrA"
                     /locus_tag="IXR05_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAQ4260613.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(9443..10282)
                     /locus_tag="IXR05_002132"
     CDS             complement(9443..10282)
                     /locus_tag="IXR05_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4260614.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            10467..11354
                     /locus_tag="IXR05_002133"
     CDS             10467..11354
                     /locus_tag="IXR05_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAQ4260615.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(11938..12633)
                     /locus_tag="IXR05_002134"
     CDS             complement(11938..12633)
                     /locus_tag="IXR05_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAQ4260616.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(12617..13015)
                     /locus_tag="IXR05_002135"
     CDS             complement(12617..13015)
                     /locus_tag="IXR05_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4260617.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3900 a         2633 c         2019 g         4464 t
ORIGIN      
        1 tgattgttat gtaaaataaa aaagtttagg atacatcgaa tttttgggga aattcttttg
       61 ggggtatcct aaatcttttc tattatattc ccatattttc tattattggt ctagacgtat
      121 gatggtaaac tttgtaccta tctgattgct gaatcattaa ttgcttatca ttagccatct
      181 ttgtttcaag ttcgctagat gatcatttta ttcacatcct aacaaacttg tcacatttat
      241 agattcttaa tctatttatc atacaattat aaaaaaggag gtgctgctta tgaaagctat
      301 ccatatttct ttgctttttt tcgctagtgc attgatttta tttgctattc atctttgttc
      361 ccagccttat atcaataaca acggaatatt agtggaacca gcattctttt gcttaccact
      421 cggctttttg tcccttcttg cctccgcagg cttcggattt gttgcttttt ttaaacgatc
      481 aaaacaacaa atctgactta taaaatttac gtaaaagaga tcgtgacaat aatcgtgtga
      541 tattcccaaa tttcgaataa aaggtgcccc ttgccatctc taactcctca gtcacaagtt
      601 acaatattca taaaccatga aaagcttgtt tattgaaatt gctccttgtg acttggagct
      661 aagtgacaga ttacaacctc ttttgcatca taagacttta ctccttgaaa aacattacta
      721 acttttgata tgtttcttgc gcttgtttat tgctgaaatc aaactgatat tcatggttca
      781 aaacagcatt tttctccgca taatctactt ttgtgacttt cacccccgct ttctcaaata
      841 cagaagttac ttcttccatt tgtttcgtaa acgtatttgt atttccatcc gttaagaatg
      901 tgttttgcgt ccaacgatcc gcatgtctga ccaaggctaa acttttgacc ttctctgatt
      961 gttcaaagtc cttattatca aagtaagccc atccacattt ttcataaaga aagctagaga
     1021 ttttatcact tacttgagta agtgcagaag gatccaacag accagacaaa gaaataaact
     1081 tcgtaatctg cttgttctcc aaagtcggat caagatgatc agctttttta atttcttcat
     1141 tttgaagtgc taacaaatat tctccactaa tttgtgcacc tgccgaattt ccaccaatcg
     1201 aaatattcga ccaatctgct tgatctttta tctctttttt agctgcttga atggcttcgt
     1261 tcaattggat aactggtgta ggatgttttg cttccggtga tcgttcataa tctatattta
     1321 cgatgatttg ctgcgtgtct gaacatagat attccaaata atcacgacaa tcatttttat
     1381 cccctcctac atatgcgcct ccatgcatcc agaaaagaat cggtaatttt ttcttttcca
     1441 ctttcggtgt gtagatatcc atattattat ttttgtactt tgaaggatag gatatttctt
     1501 tttttatatc gatttgttcg attttttgct ggaaatcatc tggtcgggca tatacttgtt
     1561 ctttttcact tgtgtcaaat tgttttctaa caagcaagct aatcggcttt ggtgtgattt
     1621 gattaatcaa aaatacagtg actaaaataa ctacgatgat aactggtact gcaatcacta
     1681 ttcgcttgaa ccatttcatt catttaccct ctctttcttc gccaaatcca tgtgataatc
     1741 gtgctaacag ataaaaatcc acctgaataa atgagaagcg aatgtttctt ttctccagtt
     1801 ttcggcaaca ttcttttttt tgcatctgtc tttttttgta ctttcactgt catctgaatc
     1861 ggttgcgtat catcacttga ttgatcctct cgaggttcat tctttccctt attgtctgca
     1921 ttctctgtcg gatcttgctt ttttggtgga gctactggga tttttttgta atagaaaata
     1981 atagttggta tcgtctcatt aaaaatccct tcagtcggtc cttcaacatt tgctaattcg
     2041 tatccttcga atgtcttttg ctctgtcata taattttctc cataagctcc gtaaagctgg
     2101 atttcgtcct ggtctttgag tagactttta ttgttttcat ccacatactt tacgtttatc
     2161 tgatcatgga acactacttt caaaaagtcc gttacatgtt tcgtgtaggc agcatggtca
     2221 acttcctgtg cctttccatg ccctgctcct tctactaata aaagatcttt ataccctcct
     2281 gataactcat ataatttttg cgcgttagac acaggtacta catcatctgc tgttccatgg
     2341 ataatcaatt taggcaatga atctgacatt ccaatcgtag gtagagcagc ttttgtatcc
     2401 aaatgcatct cctgatcaaa atagtattgt ttcaaaaggc ccataaataa atcttcatgc
     2461 tcttgatccc caatgatgtc taactgattt tttatggcat ccggtagtgc gggggctact
     2521 gtctggctgt acgtaaaacg tagttgttca tcaattgatg caaatccgca attttcaata
     2581 attcctttga cattgacagg aatatctttc gctaatacag acatcatcgt agctgctccc
     2641 atcgaaccac cataaagtaa aatcttttga gatggccgct ctcgaacttc ttgatttatc
     2701 cagtaaagga cgtcatctga ctcatattgt ccataggtca cataatcgcc tccgctatta
     2761 ccagtcgctc tggaatcaac aaataataaa ttatacccgg ccttataaaa atcattgtat
     2821 tcttctgtaa cgatcccgtt attccaattc cctcgaaatc cgccatggat catgactgtt
     2881 ttatctgaac cttgatcgac ataatatgca tatacatcca tcattttgcc atcttgtttg
     2941 tttagtacag tttgatgaag ttgttttgta tttggataga agcctgtgtt ttctgtaggc
     3001 gttgtcccat catctgtacc tccaagcatc gacatcaaca cactgttttt tgcaaaagcg
     3061 atatcgtaca atagataagt agcaatcaga tgtttgataa tctctttatc tacaccataa
     3121 tcattaacag caagctcagt gactaataac tctattaatt ttgacttgat gtcttctgtt
     3181 ggtccattaa gtatttctgt catctgttta ccgaagtaat tcaaatattc tttaccattg
     3241 aaattttcac ctttaccgat atcatcattt tctgtcccat tctctttgtc acttacttta
     3301 gcagaagagg attcgtcgtt tgacattttt gtagctgttg cttcttctgt ttgttggtta
     3361 tctgtggtag cggtcgtttc ttgatctgtg ctagtaacag atgtctcaac cgttgtttca
     3421 gtatttgttt ctgtttgtga agtactcgat ttcgtttcat ttccagcatc agtagtttct
     3481 gtggtttcta cctcccgaga ttccgattcg gaagaaatgc tctctccata tactgtccat
     3541 tgcgggacgc ttgtacttac agcaaataag atgaccaacg ctccctttaa tacttgtttt
     3601 gttctcaagc tattcactcc tttttatgtt tctaggagaa ttatatgtaa acgcaaacat
     3661 tttttataca aaaaataaat ggtttatccc ataaaaatag aacaggatta ttttctcatt
     3721 ttacgtaata aagcagaatg gataaaccag tatccattct gcttttttta aacgaagaaa
     3781 caacttattg ctccaaaaat gtcagaaatc gtttatccca aattttctcg taaaaagcga
     3841 ttgtttcctt tgctttcata aaaggattat cataagttgt cgttgctcct ctacacatca
     3901 taagctggta tcctaatcca tgagcaaact tcacagtcgt atctatacaa tactctgctt
     3961 gtgccccaca taattcgatc gaatgacagt ccaattcagt taataaaaca ctcaaattag
     4021 tcttataaaa tgaattcgca tgggtttttc tcacaaaata actgtgctca ggaatagata
     4081 attccgacaa tagctcccat ggttttgttt gtggcactaa ttgagcatct tcgtgttgaa
     4141 cgaaaataac tggtttccca atcgtttcgt atgttttgat tcttttattc actaatgctg
     4201 tcactgtttc taattcgtgt atcggcgaag aatcaaaaca tacccctttt tgtaaatcga
     4261 tcactactat tgcgtcggct gtgtttgaca tacttgtgcc ttctttcttt tttcttgatt
     4321 taatagtatt tcttatctag ctagttccat tatacgtgac aacattttct tattttacac
     4381 ctctaaatgg cacttttcga ctatttcttc atgttattat ttcataaata cttagctatt
     4441 ggaggaatgt atgatgatta aattgtatac aggttctggc tgctcgtctt caagacgcgc
     4501 aaaacgttgg cttatcgtcc atgatatacc gtttatcgaa cagaacttaa ttcgtcaacc
     4561 actaaccaaa aatgaattta tccacttact aaaattgaca aacaacggcg tgaccgaaat
     4621 gctctctact cattctatta gttataaaaa tcttgttcac agaatagatg aactcagttt
     4681 gagtgaacta tatattgaga ttcgtacatc cccttcttta ttgaaaaaac cgattatcta
     4741 cgaccaatct gcaaaacttt tgactggatt tagcgaagat aaaatcagga tgttcctttc
     4801 taaaactaaa agaaagcaag agctcaacga actcttgctt tctggtcatc ttgtcgattt
     4861 taaagaaaat aatctttttg caatgtctta attttggcat aaacaatctg cttttctgga
     4921 tctataatat ctagtgttgg tgacgccttc tgttgccaat actttttctt ttttctaata
     4981 aacgcaaaca gacaccttga aatcctttag aataaagtcg acgaaaacca ttcaaaggag
     5041 tgtttcaaga tgtcctattc agagtttacc aaagagttac tagatattct agacctaaat
     5101 cttacctttc atgaagatgc ctttcgcaaa gagcgcatta atgacgaaac atgttttgtt
     5161 tttgatggca cattgaccta tcaaccagag gaatgcttcc attgccacta tcaaaataag
     5221 caaacgatca ttaaatgggg ctggaaaaaa gtatccatct tattgaatga tgtcagtaac
     5281 tacaagacca ttgtgcggat taacaaacag cgcttcaaat gtaaacactg tggaaagact
     5341 tttttagcag aagattcagt tagcgatcgt cgctgctcca ttgcccgcag agtcaaacaa
     5401 gccattcttg agctattaag tgagcctatt tctatgtctt tgattgcacg tatgaagcac
     5461 atttctccga ccactgtcat tcgaatactt cgcagccttc ggcctaaaac cgtttctttg
     5521 aaccagccgt taccagaagt ggtgtgtttc gatgaattca aatcggtgaa aaacgtctcg
     5581 ggagccatga gctttgtcat gatggacggc aagacccatc aactgattga tattgtggaa
     5641 aatcggcaac tcaatccttt acgcgactat ttcttgcgct accctagaaa agtccgtgaa
     5701 caagtacgtc tagtggtttc agatttctat acaccctatc gcacattggt gaaagagtgt
     5761 tttccgaatg cccgaatcgt cgccgatcgc tttcatatta gccaacacat cggtcgggcc
     5821 tttaccaacc accgaattca agtaatgaag acctttaaaa aaggggatcg tcggtcgaag
     5881 cacttaaaga aatactggag actacttcaa aagaatgcgt gggaattgaa tggtcagcat
     5941 cgctactggc gtccgtcatt tcgagatcat ctgacagaag cggagatagt cgatcggcta
     6001 ttatattatg atgactcctt aaagcgaggc tacgaagtct accaggtttt tctttccgct
     6061 atcagaagac aagatgttcc tgaattcgtc gcgctcctaa aagaagacta caaggagttg
     6121 ccagagcact atcaaccagt gttcacgacc ttcaagaaat atcgaacaga aatcaaacga
     6181 gcgttgcgag ttccctattc caacggccct atagaatgtt tgaacaacca tatcaaagta
     6241 ctaaaacgaa ttgcctatgg ctttagaaac tttcaaaact accgagaacg aatcttttta
     6301 tatcgaggaa aatatttcaa gaaaactaag aacactaccc aactgactaa agccagaaca
     6361 acaacacggc tagacaagat agctgtctag ccgtgtgagt atctcgatta ttctattgaa
     6421 tttcttcacc aacactcatt gacgaagagc cgcttttctt aattaacgaa atccaatttt
     6481 tccaatatgg atctattttt ctcattcctg atttttatga tttcagcttt cagacgcgcc
     6541 caatcatttt ttgtaggttg tccattccag taaaatatct gtgtattcgt ttgatcatat
     6601 gcctttttgt cgataggata atcgctaatg acaatatcag gtaactgatc agcggatgca
     6661 ctatatttta ttgggcgttc agtcatagat aatatccttt tctttgccca taattcctgt
     6721 gttttaccat actttgattg aatatagaat atgacaggtt gttcgtgttt tataaaaata
     6781 tccctgacta acatacagta ttgaaaaatc aaccgtctgt tcttttcata ataagtatta
     6841 agctctggaa ttctgcgagc taccccacta aaaaactgtt gcatgattgg atacatcact
     6901 ggaaatatat gctgaaaatc tctgtcttct gctgattttc caaaagcatc caccttcttt
     6961 tttgtcccaa aaacccttga atacaaatgg atcattgcca aattgacata tagataattt
     7021 ttttctgaag ttgtaaaaca aatcttgaag tttttttcaa aattttctac aatagacgat
     7081 tcaatccagc cccaactttc ttgtacttta tctggagtat ccaacaaatc ttcttccaaa
     7141 taggtgttca ttacaccaaa cataaaataa aggtaagctt gctctgttgg agtgatgtga
     7201 ttcatcgacc agaagtttgc ttcaaaaaaa ggctctagta tgtaatgcgt aaactcttct
     7261 tttgttatca atggatgcac aaatttgttc atctcttctg ggacatacgt aatcgagtgg
     7321 ccttgtttca ttcgttgcaa cgaaattctt agtaggctga tccatttctt tctatctata
     7381 ctacgcgtat atggcgcatg tttcgcaaat ttttctaata gttgacgttt attttttata
     7441 cttgataata tatcagaatg attttcgtcg aatgactgcc aatacatcaa gtgaaaaaag
     7501 tatcggatac ggtattcttc tccttctatc ggattacctt ttttcaagct gcaagataaa
     7561 tgatagtttt tcaaaatagt attaagttct cttaattttc tttgaatcgt acgcaaactt
     7621 atataatttt ttgactaaga ttttctaagg attgataagt acctttgtaa agtgaatcca
     7681 gtaaaatata accaatcgtt ccctctaaaa gtatagaata aactttactc agtaaaaact
     7741 gagaagaaaa ctcgactttt atcatcttgt tttctgaaag aaaagataat ttatattctg
     7801 gatacctttc gcaaaacgat tctgcttgtt gaatcaccga attcatctta gccagggtgt
     7861 agtttagatc taaagcgata tccttcacca catataattt ctcgtctctt tcataacaat
     7921 agttcaaaaa ttgatatact tgcctttcat tgatatcaat aaattcttca aacaaagtac
     7981 atactccttt ttatctatta tttagactta ttccgacagc tacatgaata acgtacaaat
     8041 agattcgtta ctgatttttc agagatacta ccatgcgcag tgtgcattgt caattattct
     8101 tgctcttatt ttccatttgt gttcctgtta tttcctgttt ctcaaatatg ttagtaaaca
     8161 aaaatagatc tggcaaagct acaacttcgc caggcaatac agcactctcg aatgaaatat
     8221 tcactcaaaa atctatcgtt ttattcaatt ttagatctgt tgcttttatt ctttatttca
     8281 ctcgatggaa gagagaacga aaatagcttg ctcctacaat caaaatgagt aacacaccca
     8341 tccatgtaat tagcttgttc aaggttctac taccagtttc tggtaaatcg ctttttctat
     8401 tatctgtttc tttcgctttt tcttgatgat caattccacg agaaacaaaa tcaggctgtt
     8461 ttagcacact ttttaggttg ctccctgcat ttctcttttg ttccttagtt ggtatgatag
     8521 gtaccaaatc aagttcatta tttacttttc ctgtgctgct ttcgctgctc gtgcttcctg
     8581 tgctactctc actactcatg cttcctgtgc tactttcact actcgtactc tccgtactgc
     8641 tttcgctgct cgtgcttcct gtgctacttt cactactcgt actctccgta ctgctttcgc
     8701 tgctcgtgtt ttctgtgcta ctttcactgc tcgtactctc tgtactgctt tcaccgctcg
     8761 tgttttctgt actgctttca ctacttgtgc tatccgtact gcttggcggt ccaacaactg
     8821 tccaactgct tggtttcaaa ttctccgtga tcgtcatctg tccatcataa aaaacaatca
     8881 aatcaacttt atctttactc ttgatctcat caatcgatag ttctgcagaa atcattattg
     8941 tatactcaat accagcggtc cattgtacgt cttttaaata aacttcccca ataacttttt
     9001 ctgaacttcc attaccatcc caaccatatg ttagaacagc atgtacatca ctagcattca
     9061 cgcttttgtt tggtttgact ggaatagtaa tgacttgttg tgtcatgtca taaacaatcc
     9121 gatcagtttt cacagtaaat gaaagattct catttgcccg ttcatttgca gaagtactga
     9181 ttccaatcat tgctgcaatt atactcagcc caagaataac aaataatacg gtcgctgttt
     9241 tcttcatttc tatcactctc catataatta ccttctattt gataaaggaa ttatataaaa
     9301 tgaaaatgat gagaacacga cagtcagttg tgaaaatcta acaaaagatg tcgtgtattc
     9361 gcttgaattt gtttactttt tcgtttaatc aatgacagac ttaaaaaagc aagaccgata
     9421 tcagccttgc tttcttcatc ttttattgat aaacagcagt gtatttcttc atccgctttg
     9481 ttttatatgc atagagtaac aaaccaacaa tcaagactaa caagaataat gtagttgata
     9541 tagatgcttc agccccaaag tttcccccag taattattgt attttgcgat tggatcagag
     9601 tggagaaaaa accttgttct tgcgttccgc tgactggtat acccaaaata gctccttgtg
     9661 tccaattcca agtaatatga gcaccaatag ccgtaaataa acttcctgta ctgtagataa
     9721 gtgcgctgaa aaagcaacct gctaaaaaga tattgaaaac tgccagaaat gtcatgttag
     9781 gattcaatcc gtgcaaaaga gcaaataatg cagcagatcc aatcattgct attaacggac
     9841 caaatctaag catctgatgc tgaaaaaagc cacggaataa aagctcttct gatgccccca
     9901 ctgcaataaa taaaataaaa ctcgttatca gcggcacaat gtttgcgttt cctgaatcta
     9961 accgatacgc ccccgtcaaa tataatggac tagtaataag cagaaacact ccaattccaa
    10021 caacgagacc tcccgctaaa tacccccagt cttttcctcg aacagaaaca ccataatctt
    10081 ctattctttt tccttcgacc ttactagcaa gaaataaagc tagtaaaaaa acagctaaat
    10141 gtccgaccgt accggcaatt gctccaatcc attcactatt tccaataaac atatccgcaa
    10201 gtgcattatt gacaagaatt cctaaaacaa aaccaactaa gactattaaa acagatccaa
    10261 tcaaccgaat aatcctgatc atctttcatc cctcctttat attaagttta acaacccttt
    10321 tctttcttgt ctcgtgaaaa ctatgtaaat gttctccatc atagagagaa tagattttta
    10381 cgaactaaga atatctacag caaccttacg aaaatgaaag actgtctccc taattcttct
    10441 gttagactgt ttttaataag gaaaggatgg gaaatttttt gaaaaaacaa ctactaatta
    10501 tgtgcctttc agcatgtgca attttactat tctcaggttg tagcaagtcc aatgaaacga
    10561 ttgcaacgtt taaaggtgga acacttacag ttcaggattt ttatgataac ccaaaagtta
    10621 aatcaaataa tcaaacacta ttaaaaaaaa tgattgtctt caaagcattt gatgatgtat
    10681 acggaaaaga gatttcttca aaggaagtaa caaaagaata taatgaacaa atcaaaaaac
    10741 tcggtccaaa ctacaaggaa caattaaaag cagttggcca aacagaagag acatataaga
    10801 aactctttaa acagatgctg gctttccaat acggtttgaa agccaatgta aaattaacag
    10861 ataaagatct agacactgct tggaaagaat tctatccaga agttagtaca cagatcattc
    10921 tattttcgac taaagaagaa gcagataaag caaaaaaaga agcaaatgaa ggggaaaatt
    10981 tctccaagct tgttcaagct tatggaaaaa ataaaacatt aaaggaaact gatggaaaaa
    11041 tgaattttga ttcaaccaat ccagagattc ctactgaagt aaaaaaagca gcatttaaac
    11101 taaaaaacgg ggaagtttct gatatcattc ctgtaacaga tccaacgact tatcagcaaa
    11161 gctattatct agtaaaaatg gtaaaaaaac aggataaagg ttctaataaa gacaaataca
    11221 aatctgagct agaaaaaatt gctaccgaag caaaaactct tgatacggaa ttcatggata
    11281 aaacaatccg taaagtgatg aaaaaagaca atgtaactat taaagatcct tatgtaaaaa
    11341 atatattcaa ataaacaaat ttgacccaat tggggatgtg gcaaaatttg agaagtgatt
    11401 tttggaaatt ccttcttatt tttgaggcaa accacttttg ccacaacttc atcggggcct
    11461 ttttttattt gtaccaaaac aaatcactgg atttgttaca atcatgagga tataatttaa
    11521 aaaagttttt tatttctatc acatgaatca atgcgccatt aagtagattc tttcatgctt
    11581 ccctattttt tcacttgccg tatcgcttca aaaacaacta tcataaactc aaactcgact
    11641 gaaaagttat tttaaaaaag actaaaaata tcccttctgg acttgttcct cttattctgt
    11701 tatactagag aaacacgaaa gatattttta tgcgacactt ttcatttgtt tttatgaaat
    11761 ttattcaaaa ctggcgtaac ttcagagtta caaggatgta ttagaggtta gggaatacat
    11821 cgtttaaatg agaaataagt aatagtcacc caaactttaa attaatgaat attgaatcgt
    11881 cagatagcct cctcgagttt tcgagaaggc tatcgtttat tttatggaga aattgattca
    11941 gaagtaatca gcgacctttt ttagttcacc aatcgtttct gcttggaaag tttgcaccca
    12001 atcttcttgg aagcccctca ctgctttatc aatcgagggc atctctaata cttgatctag
    12061 tagctcttta cctaacgtta tcgcatgagc tccagatcga atggctgtag tgacttgttc
    12121 acaatttttg aaactagctg ctaatatttt tgttggtctt tgcgtacgtt cgatctcagt
    12181 ccgcaacgaa tcaatcactt tcatagcatc aatgccttga ttttgcatcc tgttataata
    12241 aggtgcaata taatctgctc cattattaat agctaaatac ccttgtaatt ctgtgtaaat
    12301 agctgtaccg gtaatcaaat aaccttcttt tttcaacttt ttgatcgctt gaaggcctgc
    12361 ttgattcacc ggcaccttga taaacgtatc ttttcccagt tcttctatga taactcgagc
    12421 atcctctatc atttcttctt ccgttcttcc tattgtctga atatggatag gaatctgtcc
    12481 gattattttt ttgatttctt tcatatgcga gaagaagttt gacgctcctt cttttttcag
    12541 aattgtagga tttgttgtta cgcctgttaa attcaaaaac tgttgacaag aataaatact
    12601 ttttgtattt gctgtatcaa gcatgatttc catatagctt tcccccattc tgatcctctt
    12661 gatcgatttt aatgattgtc ccctttctta aatgcggcat ttccttatct tctacataca
    12721 ttgttcctgg aagttccggc tcatgagatc catcaaattt tatcgtgata tgtcctaatt
    12781 cattcaaatt agtttggaca acatctccta ctgctgtgat tacatacatt tgtttatcaa
    12841 aacagagctt catatcacaa gttatttctt ttcttacctg attcaattca atcttataac
    12901 aataatctgt taatgtttcc ggtgcttcat ctccaaataa aatcattatt ttttctttcc
    12961 tgaatacttc tgcttctata ccaacatctg ttacaaccgt ttcaaagatc gtcatc
//
LOCUS       DACGDM010000075        12911 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.079, whole genome shotgun sequence.
ACCESSION   DACGDM010000075 DACGDM010000000
VERSION     DACGDM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.079"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            133..3660
                     /locus_tag="IXR05_002136"
     CDS             133..3660
                     /locus_tag="IXR05_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4260618.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="IXR05_002137"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="IXR05_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAQ4260619.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="IXR05_002138"
     CDS             7448..7789
                     /locus_tag="IXR05_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4260620.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="IXR05_002139"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="IXR05_002139"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4260621.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="IXR05_002140"
     CDS             9146..11566
                     /locus_tag="IXR05_002140"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAQ4260622.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IXR05_002141"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IXR05_002141"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAQ4260623.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4385 a         2243 c         2739 g         3544 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac t
//
LOCUS       DACGDM010000076        12734 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.080, whole genome shotgun sequence.
ACCESSION   DACGDM010000076 DACGDM010000000
VERSION     DACGDM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.080"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="IXR05_002142"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="IXR05_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAQ4260624.1"
                     /translation="MAVLARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="IXR05_002143"
     CDS             complement(322..891)
                     /locus_tag="IXR05_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAQ4260625.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="IXR05_002144"
     CDS             1077..1979
                     /locus_tag="IXR05_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4260626.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="IXR05_002145"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="IXR05_002145"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAQ4260627.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="IXR05_002146"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="IXR05_002146"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAQ4260628.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="IXR05_002147"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="IXR05_002147"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAQ4260629.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="IXR05_002148"
     CDS             8547..8732
                     /locus_tag="IXR05_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAQ4260630.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="IXR05_002149"
     CDS             complement(8794..9990)
                     /locus_tag="IXR05_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4260631.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVARAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="IXR05_002150"
     CDS             complement(10160..11596)
                     /locus_tag="IXR05_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4260632.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="IXR05_002151"
     CDS             11889..12698
                     /locus_tag="IXR05_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4260633.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2675 c         2249 g         4007 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctagtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcac gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaacgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gaca
//
LOCUS       DACGDM010000077        12548 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.082, whole genome shotgun sequence.
ACCESSION   DACGDM010000077 DACGDM010000000
VERSION     DACGDM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.082"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            47..784
                     /locus_tag="IXR05_002152"
     CDS             47..784
                     /locus_tag="IXR05_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260634.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            798..1613
                     /locus_tag="IXR05_002153"
     CDS             798..1613
                     /locus_tag="IXR05_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4260635.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1626..2273
                     /locus_tag="IXR05_002154"
     CDS             1626..2273
                     /locus_tag="IXR05_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4260636.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2289..2945
                     /locus_tag="IXR05_002155"
     CDS             2289..2945
                     /locus_tag="IXR05_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4260637.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            3107..3928
                     /gene="racE"
                     /locus_tag="IXR05_002156"
     CDS             3107..3928
                     /gene="racE"
                     /locus_tag="IXR05_002156"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAQ4260638.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            3931..5286
                     /gene="rph"
                     /locus_tag="IXR05_002157"
     CDS             3931..5286
                     /gene="rph"
                     /locus_tag="IXR05_002157"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAQ4260639.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            5287..5805
                     /locus_tag="IXR05_002158"
     CDS             5287..5805
                     /locus_tag="IXR05_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAQ4260640.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            5912..6412
                     /locus_tag="IXR05_002159"
     CDS             5912..6412
                     /locus_tag="IXR05_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4260641.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(6692..7612)
                     /locus_tag="IXR05_002160"
     CDS             complement(6692..7612)
                     /locus_tag="IXR05_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAQ4260642.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            7777..8790
                     /locus_tag="IXR05_002161"
     CDS             7777..8790
                     /locus_tag="IXR05_002161"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAQ4260643.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(8900..9655)
                     /gene="fabI"
                     /locus_tag="IXR05_002162"
     CDS             complement(8900..9655)
                     /gene="fabI"
                     /locus_tag="IXR05_002162"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAQ4260644.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            9875..10315
                     /gene="fabZ"
                     /locus_tag="IXR05_002163"
     CDS             9875..10315
                     /gene="fabZ"
                     /locus_tag="IXR05_002163"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4260645.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(10430..11191)
                     /locus_tag="IXR05_002164"
     CDS             complement(10430..11191)
                     /locus_tag="IXR05_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4260646.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            11380..12474
                     /locus_tag="IXR05_002165"
     CDS             11380..12474
                     /locus_tag="IXR05_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4260647.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         4045 a         2177 c         2642 g         3684 t
ORIGIN      
        1 catctttaaa agaaatctta ctaaataata atgggagtgt aattctatgg caatgattaa
       61 atttgatcac gtggataaat attatggcaa gttccacgca ttaaaaaata tcaatctcga
      121 attcgagaaa ggagaagttg tcgttgtcat tggtccttct ggttcaggaa agagcacgat
      181 gcttcgctgt atcaatggat tagagacgat ctcttcaggt aagctgctga ttaatgatac
      241 tgacttgcat gataaaaaga caaaactgac agaagtccga aaaaacatcg gcatggtttt
      301 ccaacatttc aatttgtacc caaataaaac tgttctggaa aacatcaaat tagcaccaat
      361 caaagtgttg aagcaagacc aggcaactgc agtcaaaaac gcggagaaat ttttgaaaac
      421 tgtcaatatg ttagataaga aagattctta tccttccatg ttatccgggg gacaacagca
      481 acgggtggca atcgccagag gtttagcgat gaatcctgag atgctgctgt ttgatgaacc
      541 tacttctgct ttggatccgg aaatgattgg tgatgtatta gacgttatga aaaaattggc
      601 tcatgacggt atgtcaatga ttgtcgtgac acatgaaatg ggctttgcca aagaagtggc
      661 ggatcgtgtt atcttcatgg ctgatggaga agtattggaa gacagcagaa atgtgagaga
      721 ctttttcgaa aatccaaatg aagtccgagc acagcaattt atcagtaaag ttatcaatca
      781 ttgataggag gaaaaagatg cgcaggttaa aaaaaatacg cctgattttc cttttaggca
      841 ttgcttttct tgcactagcc ggatgtaaag gaaatgggtt ggcaaatgaa gatattttag
      901 agcgaagcaa atctaccaat gaaatcatct ggggtgtcaa gtatgatact cgattatttg
      961 gaatgatgga tattgagagc agaactgtac aaggatttga tgtagatatt gcaaaagcaa
     1021 tcactaaaaa gatccttggt gacaatggaa aaacagaatt tgttgaagtc acttctaaaa
     1081 ctcggattcc attattgaaa aacggaaata tcgatgcaat tattgcaacg atgacgatca
     1141 cagatgaacg aaaaaaacag gttgactttt cagatgtcta tttcgatgct ggccaagctt
     1201 tgttggtaaa gaaaggaagc caaatcaaaa gtgtagatga tttgaatgct tctacaacgg
     1261 ttctagcagt caaaggttct acatcggctg cgaatatccg acagcatgca ccagatgcaa
     1321 aaattttaga attagaaaac tatgcagaag catttactgc tttacaatct ggtcagggag
     1381 acgcgatgac tacggataat gcgattttgt tagggattgc agatgaaaat ccagagtatg
     1441 agttagttgg tggaacgttt actaatgagc cttacgggat tgcgatcaac aaagggcaag
     1501 aaaacttctt gaaagctgtt aaccaagcgc tagaggaaat gcatgcagat ggcacatacg
     1561 ataaaatcta tcaaaaatgg tttccaaatg aaactgaagg aaaagtagag taagggggag
     1621 aggcaatgag cgaattgata caaacttatg gaccaatctt tgtcgacggg ttcaagatca
     1681 cattgttttc gagtgtctta gcacttgtgt ttagtttgat tatcggaacg ttaatggcaa
     1741 tcttccaatt atcaaagaat aaagtagtga gcgccttagc aaaggcatat gtagaatttt
     1801 ttagaaacat tccattatta atcatcgtga tgttttttta tgttgtcgta ccgatttatt
     1861 ggtttaatct agatggattc caagcaggta cgattggatt aacgatctat acatctgctt
     1921 ttattgctga aacagtacgt tcagggattc aaaccgtacc aaaaggtcaa acagaagcag
     1981 gactatcttc tggttttacc tattcagaaa tcatgcgtta tattgtttta ccgcaagcat
     2041 tcaaaatcgt tatcccgcca ttaggcaacc aatttatcaa cctcgtaaaa aactcatcta
     2101 ttttagcaat cgtagctggt ttagatttga tgtatcaagg agacttgatc gctagtgaaa
     2161 cattcaatac cttcgatacg tatatcatcg ttgggttatt ttacttagtt atcacgctac
     2221 cgttatctta cttaatggtt tatcttgaga aaaaatgggc ggttcgttca tagaaggagg
     2281 ggaaatacat ggattttagc ggcgcttttt catggatgaa tatccgtttt ttattggaag
     2341 gattaaaggt tactgttgaa gtttcattgt tttcgatcat ttttagtttc ttgatcggtg
     2401 gtctgacagg tgtgattcgt tttgcgaata tccctttctt ttccaaaatc cttggtgtag
     2461 tgattgatat tatacggaat cttccattat tattgatcat tttcttcact tactttgcct
     2521 tacctcaaat cggcattcag atgaacatct tctggtccgc tgtcgcagca ttaacgattt
     2581 ttgagtcagc tatgttgtcg gaaattttcc gagctggact caatgctgtt ccaaaaggac
     2641 agatggaagc aggattatca acgggactga cttatgtaga atcgatgcga acgatcgtgt
     2701 taccgcaagc atttaaatca atgatcccgg caattgtgag ccaattgatt tcactgatca
     2761 aagatacttc attagcagta atcatttctt tacctgaact ttctcatcag gcacgtatta
     2821 tttatggaca gaacaccaat tatgtgcttc cgatgttcat catcatgaca cttatgtact
     2881 tcgtggtatg ttacgcgctt tctctgcttt ccggttactt ggaaaagaga cggtacagtt
     2941 attaatagat gattctttta gcggttgtgg caaactaaag tcacaaccgc ttttcctctt
     3001 tccattcgaa aaaaagagat ttcgattgtt ttaagcaagt aagagcactt gaaaattcac
     3061 gctaaaaagt acacaatagg gaggatagaa tttattgaaa aaaaggatga tacgattgac
     3121 agataatcgc cctatcggat ttattgattc aggtgtcggc ggcttgactg tagtaaaaga
     3181 agccctgaaa caattaccga atgaaaatat tttatttgta ggagacacag cacgctgccc
     3241 atatggccct agacccgcgg aacaggtaat ccagtatact tgggaaatga cggattatct
     3301 ggtggagcaa ggaatcaaga tgctggtgat cgcctgcaat accgcaactg cggtggcttt
     3361 agaagaaatc aaagctgctc tttctattcc agtcatcggt gtgatccttc ccggtactag
     3421 agcggcagta aaaaaaacac aaaataaaca agttggcatt atcggtacga ttggtacggt
     3481 aaaaagtcaa gcttatgaaa aagcactgaa agagaaagta ccagaattga ctgtgacaag
     3541 tcttgcttgt cccaaatttg tttcagttgt cgaaagtaat gaataccatt catcggtggc
     3601 gaaaaaaatt gtggcagaaa cattagctcc tttaaccact aaaaaaatcg atacattgat
     3661 tttgggatgc acccattatc cattattacg ccccatcatt caaaatgtaa tgggagaaaa
     3721 tgttcaactg atcgattctg gagcagaaac agtaggtgaa gtatctatgc tgttagatta
     3781 tttcaatttg agcaattcac cgcaaaatgg tcggacatta tgccagtttt atacaactgg
     3841 ctctgccaaa cttttcgagg aaatagctga agactggctt ggaatcggac acttaaatgt
     3901 agaacatatc gaattgggag gaaaataagg atgcgtcatg acgggagaaa agcccaagag
     3961 cttcgcaaac tggagcttca aacaaatgtt ttcaaatatc cagaaggatc ggtagtgatc
     4021 cgttttggtg atacaacagt tatttgttct gcaacaatag aaaattctgt tccccctttt
     4081 ttgagagaaa caggaacagg atgggtgaca gcagaatata gtatgctgcc tcgagcaacg
     4141 agtacgagaa atcgtagaga aagcagcaaa gggaaacttt ctggtagaac aatggaaatc
     4201 cagcgtctta ttggtcgttc cttgcgtgca gtagtagact tggaaaaatt aggagaacgt
     4261 agtatcatcg tagactgcga tgtgatccaa gcggatggcg gtactagaac agcaagtatc
     4321 actggggcat ttgtggcatt gaaattagcc attgaaaaac ttttaagaga aaaagaattg
     4381 tcagaagatc caataaaaga acatcttgct gcagttagcg taggaatctt accagatggg
     4441 acttgcgtca cagatttgga ttaccaagaa gattccgcag cacttgtaga catgaatctt
     4501 gtaatgacag aatctggaaa attcgtggag attcaaggaa ctggagaaga agcaacgttt
     4561 gatggtgaac agttgaatga aatgctcttt tttggaaaaa acgcgattga agatttgatc
     4621 aaagagcaaa aacatgcttt gctaacagag tttgctcaaa atgatgagcg gatagaagaa
     4681 acaaaaacaa tcatcattgc gacaagaaat ccaggaaaag cagaagagtt tcgaaatatg
     4741 ttcaaagaag cgggatatca tgtaaaaaca ttacttgact atcctgaatt gccagatgtg
     4801 gaagaaactg gcagcacatt tgaagaaaat gcccgattaa aagcagaaac gattgcacaa
     4861 ttgcttgatc agccagtctt agcagatgat tcaggtttga aagtggatgc tttaggcggt
     4921 atgccaggaa tctattctgc acgttttgca ggggaacaaa aaagtgatgc ggggaataac
     4981 gccaaattat tatatgaatt gacagatgtg ccggatgaaa aaagaacagc acaattccat
     5041 tgtacgttag tattcgcggc acccaaaaaa gacagccttg tagtagaagc ggaatggccc
     5101 ggtcgagtag cccgtatacc atctggcgaa aatggctttg ggtatgatcc tttatttatc
     5161 ccagaaggta agaaacaaac agcagcagaa ttatcgagcg aagaaaaaaa caagatcagt
     5221 catcgggctc aagcaatgaa aaaattgagt gccgagtgga aacaatggct ggaaggagag
     5281 agatagatgc ggtatttagt agtaagtgat aatcatggag acagagatat cctcgttgac
     5341 ttagtagatc gttatcgttc tgaagtggat atctttttcc attgtggtga ttcggaatta
     5401 gaagcttctg acccattatg ggatacattc caagtggttc aaggtaattg tgattatgga
     5461 ccaggattcg aacagaaaaa agtgatccaa actggtcagg atacagtatt catgactcac
     5521 ggtcatttat cgaatgtccg atttggtttg acacagttag caatcgaagc tcgagctgca
     5581 actgccgata tggtgttttt tggtcatacc catcaaatag gctgtgagat ggatcagaaa
     5641 atcctgtttt tgaatcctgg tagcatttct cagcctagag gcccgatcca aatcccatca
     5701 tatgctctta tcgaaagttt agatgaccaa atttctgttc aatactataa ccgtgcccat
     5761 caggcagttg aagagttggc cttttctttt tcgagagagc gctgaataaa aaaactctaa
     5821 tttttaataa aaataagctt tattttatga attttgcatc cggtttcggt aaaatagtag
     5881 tgttgaatga aatagaaatg gaggccatca gatgattgga cctatagtaa gagaaatgct
     5941 gctggaaaat caggaaacgt ttttgattcc tgcagaaaat gtggcaaatg ttatgtatca
     6001 tcatccattg tcccatggtt tacttgtgtt atcgaaggtc ggttattcca aaattcctgt
     6061 attaggaaaa gatgatcact ttgtaggact agtaagttta tcagatgtgg tcaataaaat
     6121 gattgacttg caaacaatca gcatggaccc gttagaagga ctaacggttg ctgatgtgac
     6181 agaaacagat gttccgacaa ttgatgaaaa ttgggaacta gaagaagtac tccatttgtt
     6241 agtcgattcg ccttttttac cggttgtcac agaagatcgg attttcaaag gaatcattac
     6301 aagaaaagag ctgcttaaag ccgtaaactt catggtgcat gaattagaac gtcgtaatat
     6361 attgtctccg aaaatcgaag aattaaaaga acaaatcgat atcgtgagct aaagaacgag
     6421 aaactaaaag ataatcaaaa aataagtaga aaaaacagcg taccagtttt gactttatct
     6481 tgaaaaagag gctgggacaa aagcgtttaa ctccaagaaa taagaaggaa ttcacgaaaa
     6541 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc
     6601 cgtttatacg tgtttagagc gtgggacaaa agtgttcttt acttttgtcc cacgctcttt
     6661 ttagtgagat tcgttgcatc gtttgtccaa attattttcc gacagcaatt ggactgttcg
     6721 gaatcgtgaa accagaagct gtcaattctt tgacatagga gctcaagaac tcttctttta
     6781 aggcatattg ttttccgttc aatgcgtagc agaccgtacg aatcgcaaaa ttgctgtttc
     6841 caagatccac taatccaaag atagaaggtt cagtttggag ctcttcttgg tatttttcag
     6901 ctaatgtacg atttactcga tcaatgatct catagatttt gtcatatcct tcttcaggaa
     6961 caatccgaat atctaaaagt acttgcatat ttgcacgaga gagattgctg atcgtggtga
     7021 tgtttcgatt cgggatgaaa tggacagtac catccgttgc tttcagctga agggtacgga
     7081 taccaacaga tacgacggtt ccttcaatcg ttaagtttgc tagcttgatg tagtccccaa
     7141 catccatctg ttgttccatg ataataaaaa atccggtaat aacatcactc atgaaccctt
     7201 gggcaccaag accgattgcc acacctgcaa ttccggcacc agccaaaagt gatccgatcg
     7261 gcacaccgat agcagataaa attgcataga taaaaaagaa accaagggta taatgaaaaa
     7321 tagtatttaa aagactatgt aaagtcttta agcggctctc gtttagaatg gcttttttag
     7381 aatactgatt aaaagactta tcaatcagat attttcccac acggtgaaga atccaaaaaa
     7441 ggacgatcaa aaaaatcaga tataaacttt tttggataaa ggcagccaaa atggcgtccc
     7501 aatcaatccc gtcccaaaac cgctgaaacg catttacttt gctgacagct tgatctgtca
     7561 atgtctcgcc agaagagtct gtcgtaccgg cagttgctaa taatgaaaac ataaaatcct
     7621 cttttctaaa atttgattct ttctgtattg taccaagaag ttttcaaaaa aggaaatagc
     7681 aaaaataact ataatgaagg aaaaaagctg aaaataaaat gacaaataat atggataatg
     7741 ataaaatgtg gagaaaataa cgaaggtggt aagtatatgc aaatcgattg gaacaatcta
     7801 ggtttttctt atatcaaaac tccttggcgt tttattgcca aatggaaaga cggacaatgg
     7861 gaagaaggag aattgacaga agataattac ctgacgattc atgaaggctc tccagcgctt
     7921 cattatggtc agcaatgttt tgaaggtcta aaagcttatc gtcgaaaaga cggcaaggtc
     7981 aatctctttc gacctgaaca aaatagtcga cggatgaatc aaagtgctag acgattgctg
     8041 atgccaatgg tccctgaaaa gatgttcgtt gatgctgtca agcaagtggt aaaagcaaat
     8101 gaagattttg tgccgcccta tggaacaggc gctacattat acttgcgccc tttactgatt
     8161 ggggtcggtg aaaacattgg tgtccatcca gctccagaat atttatttgt cgtcttctgt
     8221 acgccagtag gagcgtattt caaaggtgga ctaaaaccaa cgaattttat tgtatctgat
     8281 tacgatcgtg ctgctcctaa ggggactggt gcagcaaaag tcggcggaaa ttacgcagcg
     8341 agtttacttc caggaacaga agcaaaagaa ctggattact cagattgtgt ttatcttgat
     8401 ccagccacac atacgaaaat cgaagaagta ggtgcagcaa atttctttgg aattacaaaa
     8461 gacggaaaat tcatcactcc gcaatcgccc tctatcttac caagtatcac gaaatattcc
     8521 ttgttgcagt tagctgaaga acgactagga ctgcaagcaa ttgaaggaga tattttcatt
     8581 gatgatctag atcaatttgc agaagctggt gcatgtggta cagcggctgt tatttctcca
     8641 atcggtggga tttatcacaa taacaatctt catgtatttt atagtgaaac ggaagtagga
     8701 ccagtaacaa aacggttgta tgatgaattg acaggtattc aatttggaga catagaagca
     8761 ccagaaggct ggattgaagt cgtggaataa tttcaaagta atgagttgaa aaaaacgtaa
     8821 aaagaaaaaa tcaggaagag actttaaaaa gttttttcct gatttttata tgttttactt
     8881 taaagaatgc aacaaaagtt tatgaaagat ggacaccttt gtcaacgtag ataatatcac
     8941 cgatgattcc gctggaaagt gggctgatta agaaagcaca agcattaccg acttcttcga
     9001 tcgtcacacc ttgctgatca ggcgtacgag attcagataa ctggatcagt ttttgatagt
     9061 ctttaacacc tgtgacagct aatgttttga ttgccccagc tgagattcca ttgacccgaa
     9121 ttcctttagg cgagaactca gctgccaaat aacggatagc agcttcaaga gaagctttcg
     9181 caatacccat catgttataa ttcgggattg cgcgttctga acctagataa gtcatgctaa
     9241 cgatcccgct gtttggtgca agaaacggtt gtgcgtattt tgatacagca attaaagagt
     9301 agctgctgat atcttgagct aattgatagc cgtctctgga aatatcagac acatttccgg
     9361 acaattcttc tttgttggcg taagcaactg catggacaag gccgtggatc tccccagcat
     9421 attcaccgat ggcattcatt gctttttcga tgctttcgtc gctagaaaca tcacattcta
     9481 cagtgaatgc ttcttcgccg accaatttga ctaatgattt tttcattcgt tcattttggt
     9541 aagtatagat aatttctgcc ccttgtttca acattgcttc agcacaaccc caagcaatgc
     9601 tttttttgtt agcgacgccc ataatgacga ttttttttcc ttctagaaat gacataatga
     9661 ctctcctttg tttctgataa aaatttgata gtcgtaaaaa aatagagaat aatagctaaa
     9721 ataacttctt gatttcttaa ttattagtca aaatgttttg attgtcaaac tattttttct
     9781 taaattaaaa aaagattgct aaatatttag gaatatgata ctttgatagt caaagtaatg
     9841 aaaatggcaa ttgcctgaaa gaaggagttt aattatgtct tacgtattat ctgctactga
     9901 agtaatggaa ttgattccta atcgttatcc tatttgttat attgattatg tagatacttt
     9961 agaaccagga aaaaagatcg ttgcgacaaa aaatgtaaca atcaatgaag attttttcca
    10021 aggtcacttt cctgacaatc cagtgatgcc gggtgcgttg attctagaaa cactggcaca
    10081 agcaggttcg atacttatcc taaaatcaga agagtttcta ggaaaaagag cttatatcgg
    10141 tgggatcaat aaggccaaat tccgtcaaaa agttgttcca ggagatgtgc tgaaatgtca
    10201 ttttgaaatc accaaaatga agggatcagt cggtacagcg ttatctgcag catatgtaga
    10261 tgataaaaaa gtctgtgagt gcgagttcac gttcatcgtc aaccaaaatg cttgactata
    10321 aaacctgata tagcaaaaca aaaggaagct tacttgcttt ttatgtaaaa agaagacgcc
    10381 tgaatcctag catacgttgt catctatgca ggattcagac gttatttttt tatttttgtt
    10441 ttgcttcttg cagtatattg attttatcga tttttacttc ttcttttggt ttgtctgaac
    10501 tatctgtttc gatatttgca atagcatcca cgacatccat tccttcaatc acttggccga
    10561 agacagtata atggccatct agtgaaggat aaccgccgtt tttataagcg tcgatgattg
    10621 cttgaggata gtcgtctttt aaaagaccat catgcatatc atctgtattt tgaacgataa
    10681 agaactggct gccgttactg ttaggatctt gtgagcgagc catagataac gcacctctta
    10741 tattataaag gtggttgttg atctctgttt caaatccttc tccccaaatg ctttcccctc
    10801 cagtgccatc gcctttagga tcgccacctt ggatcatgaa atctttgatg acgcgatgga
    10861 aagtcagtcc gttgtagtaa ccgtcttttg catgtgtcat aaagttttca accgcttttg
    10921 gtgcgtgttc gggaaataat ttgattttga ttgtgccttt attcgtcacc atttcgacca
    10981 gatcttcatt ttcggcgaca tctttcgtca attgtggtaa ttccaatgcg ttcaaatcga
    11041 cgctactggc agtcgtgctt tccgcagtag atgtactttt tgaactttct gtagacgaac
    11101 tagaagaagt cgtgttgttt gcagaacaac cagcagcaaa cagcaatgct gctgctaaac
    11161 taatacttaa aataacttta tttttcttca taactgttcc tttccaattt actattttgt
    11221 tatctttaat gataacaaaa tagagggaaa atacctactt aaattattgg aatttatcat
    11281 ttattttaaa agaaaaagaa aaggtgtaga ccatttactt tgtgtttgct ataatgtaag
    11341 tggatacaaa aacgaaaaga tgcaggagga aatggtaata tgggaaaatt aggaatctcg
    11401 atttatccag aacggtcaac atttgaaaag gacaaagcgt acttggattt agctcataag
    11461 tatgggtata aacgggtttt taccagtttg ctgcagatca atgatgataa agaaaaagtt
    11521 ctttcagaat ttaaagaagt agttgattac gcgaatagcc taggcatgga agtaatggtt
    11581 gatatcaatc cagcgttatt tgaacagttg gagatttctt acgatgactt atcttttttc
    11641 cataagatgg gtgcctacgg ggtccgctta gatatcggat tcacaggagc agaagaagca
    11701 aaaatgacgc gcaatccttt tggtatcaaa atcgagatca atatgagttc gggcacgaat
    11761 tacgttgaca acatcatgag ttattcgcca aacacggata atttattagg ttctcataat
    11821 ttttatcctc atcgatactc tggtttagga tacgaacact ttgttttttg ttcagaaaaa
    11881 ttcagaaaat ataatttgaa tacgatggca ttcgtcaatt cgcaatctgc tgagtttggc
    11941 ccttggccta cgcaagatgg cttgtgcacg ctggaagacc accgagatct tgaaattgcg
    12001 acacaagtga agcatttaat ccttacagga ttgattgatg atatttctat tggaaatgcg
    12061 tacgcaagtg aagaagaatt gaaagaaatg gcagaagcat ttaacgcgga ttatccaaca
    12121 ttgaaagtag atacggaaga aggtattaca gaaaacgaac gaatctgctt gtttgataac
    12181 cttcatagtt atcgagggga tcgctcagaa tatatccttc gttcaacgat gactcgtgta
    12241 tactacaaag ataaagattt cccgcctcat aatacgcgag atatgcatca tggggatgta
    12301 ctgattgaca atgaagggta cggtcaatac aaaggagaaa cacaaatcgc cttgaaggat
    12361 atgaaaaacg acggacgtgt caatgttgta ggaagaatct ccgatgacga attattcctc
    12421 cttgactttt tgaaaccatg gtcaagcttt aaattaattg aaaataaaaa atagataatt
    12481 agttattgca gaaataatcc gctagaaata gccagttatt tctgcttttt tattttgttt
    12541 ttttatag
//
LOCUS       DACGDM010000078        11667 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.083, whole genome shotgun sequence.
ACCESSION   DACGDM010000078 DACGDM010000000
VERSION     DACGDM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.083"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(37..216)
                     /locus_tag="IXR05_002166"
     CDS             complement(37..216)
                     /locus_tag="IXR05_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260648.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(597..1304)
                     /locus_tag="IXR05_002167"
     CDS             complement(597..1304)
                     /locus_tag="IXR05_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260649.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(1297..1734)
                     /locus_tag="IXR05_002168"
     CDS             complement(1297..1734)
                     /locus_tag="IXR05_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260650.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            complement(1749..2000)
                     /locus_tag="IXR05_002169"
     CDS             complement(1749..2000)
                     /locus_tag="IXR05_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260651.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            complement(2000..2206)
                     /locus_tag="IXR05_002170"
     CDS             complement(2000..2206)
                     /locus_tag="IXR05_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAQ4260652.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            complement(2643..2903)
                     /locus_tag="IXR05_002171"
     CDS             complement(2643..2903)
                     /locus_tag="IXR05_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260653.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            2978..3181
                     /locus_tag="IXR05_002172"
     CDS             2978..3181
                     /locus_tag="IXR05_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAQ4260654.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(3322..3807)
                     /gene="ssb"
                     /locus_tag="IXR05_002173"
     CDS             complement(3322..3807)
                     /gene="ssb"
                     /locus_tag="IXR05_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4260655.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(3810..4709)
                     /locus_tag="IXR05_002174"
     CDS             complement(3810..4709)
                     /locus_tag="IXR05_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAQ4260656.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            complement(4722..5315)
                     /locus_tag="IXR05_002175"
     CDS             complement(4722..5315)
                     /locus_tag="IXR05_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAQ4260657.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            complement(5556..7760)
                     /gene="topB"
                     /locus_tag="IXR05_002176"
     CDS             complement(5556..7760)
                     /gene="topB"
                     /locus_tag="IXR05_002176"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4260658.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(7771..9231)
                     /locus_tag="IXR05_002177"
     CDS             complement(7771..9231)
                     /locus_tag="IXR05_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAQ4260659.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            complement(9292..11664)
                     /locus_tag="IXR05_002178"
     CDS             complement(9292..11664)
                     /locus_tag="IXR05_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260660.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
BASE COUNT         2892 a         2432 c         1957 g         4386 t
ORIGIN      
        1 tgctatcact tttagttttt aggataaaaa gtgacgtcac tttttgagtg ctggtacctc
       61 aaatcctgct ttttcttggg caatcaataa atctaacgca atacacataa tcctggattc
      121 acttttgccg tacttctgct ttagttgctg caattctttt tgtctctttt catccaacgt
      181 cacgggtaac cgtttatttc ctattgcaat tggcattagt actctctcct ttcatcgaaa
      241 taaccctatt aaaaatatgg ctgcaatcaa cttgaatatt agactcacaa gggttaacac
      301 aaagcgccaa aagatcaaac aaaataccag tattcctaag aatactacga agtttaaatg
      361 tagagctgca ccatgacgca taagtatctc gccaacaaac agtacgaaca atagaggaat
      421 gattttattc atatggatct ccttctttct cttaggttat cgggctttgc ccgcttattt
      481 cgcaccacct aagcggcggg ggcggttgga tcgattggtg cgaaataaga accattccct
      541 taatttcaag gttttttgtt cttatttcac acatcctcac ttttcggtat aaatggttat
      601 tgaccttttt tcctttcaaa tcgttgatat ggcattcgtt tacggtcaag ttcattttgg
      661 atttcttctg tatcgtcgta agtgtaggtg tctaaaaaat cagttaaagt cgtgtaccag
      721 tcgtcgcctg ggttatctac ttcttctaca tattccctca aaaatgcttc gggtacagtg
      781 agttcataat ccattcccat taacacgata gattccgtcc cacacgtcaa aaatctagta
      841 aatacaaggt aataatcgtc taccgtcgca tctttgctgt ttagctcttc catttcttct
      901 tccattaatt ccatgctctc aaaaattgaa taatattctg attctgagta atagtgtttc
      961 ctgcaaatcg tgtagctgac aaagttttcg accagctcac tcctttctag gtaaacattc
     1021 atgatatatt tttctgtttc tagtcgtaga agctccgctc ctttttttaa tgtgtcagga
     1081 cgacgtttat acacgtctaa acgattatgg ctgactgtaa ccttcgtttg actcgtttca
     1141 ctttccatat acaactgttc ttccactctt tgaataaagt acttcatttc ttccatacaa
     1201 ctaaagtctt tttgaatccg tctgattact tcattcaagt gttctttgtt tgttaaaaat
     1261 tgcgaaacat cttctgttgt tagctgataa accaccttat tcattatctt tctcctccga
     1321 ttcaatcgta taaaatgcac catttttttc gatattttca aaagtatcta gccagtcgct
     1381 agccattgct ttagctttct taatctgtgc gaattttgca taagtcagtt ctaaggcttg
     1441 atattcggaa ggtttgatag tgcttggttt gacacctact tccaagcata gtaaggcttg
     1501 gaaaaaccat tttccatttt gttttttcag ttcttccagt gttcgatagt acgtcgcaat
     1561 gagattcatt tcgacacctg attcaatcat ttcttccact gcgactgaca atttttcctt
     1621 gtaatgtttt ttgggtacac gtgtttcatg gtataggaac gtcatatcct ccattttttg
     1681 tgccatttta tccaaaggta atttgacaaa ttcgtcatag taattttgag ccatattttt
     1741 tctccttttt agttctctaa tttggttaac caatattcga tttcataagt ttccatgttt
     1801 tcttgataat gcagttcata tcctgcaatc ttcactaggt cttcaaatag catagtcggt
     1861 gcatcctcta ctaaaggggt ttctatcgtc cagtaccgcg gaataagtaa agcttctgct
     1921 actttttcag aaatgacttc tttgtccacc aaaatttgaa cgacttcttt tacagtcaat
     1981 aatttgtgtt gtgttttcat caccgtttct ttactttctc atcaatcaaa acataatcgc
     2041 cataagacaa ggtatatttt ttcccgcatg ttggacattg atacaaacga tagcttttga
     2101 tacatttcgc tctttctcca caatcgcatt cgacagtatg tggtgcatga tagtttggga
     2161 ataattcgct gaagggaaca ccccaataat caaatttctt tcgcatgatt gattctgcct
     2221 cctcttagga aaggttttat ttcctttcgt tagttctttc tttattgatt tgttggccag
     2281 aatgaatcaa cgaaaagcga caaggacaag ggcgcgcagc gtgccattta cccttgtcct
     2341 tgtcgctttt tggtgataaa aggcaacttg ttgccggtct ggcaaatcaa taaagagata
     2401 gcgaacagga acgaaccttt tggtgagagg aagttttttc tattttgtct tgctttgcaa
     2461 gacaccatat cttagtgaac gtgcaacgtt cacttccttt cttctcgaac ggcggtggcg
     2521 gttggagtga gagaaaggtt tttcaattga gaaggcactt gtgtcttcct aaaaaggtct
     2581 tttcctgttt ctatgtaaaa caaaaagagc tgcaatcctc atttaggact gcagctcttc
     2641 ttttatatgc ccatcgatcg cgtaaaatga tcggggtttc taatttgcat cgattcaatg
     2701 actaattgat tccgtttatt gaaatgacct gtgacggcaa tattgtattt tccatcatcc
     2761 ataattaaca atttatcgat aatttcaata tctgcaacta cacaattaat cgattcatga
     2821 attgtttgta aagtaaagcg aaccaataat ggttgtgttt ttattactcg gattttatca
     2881 agcaaaccaa catatttgtt catcacgatc acctcgctaa aattatagca aaaacagcta
     2941 aaattgagaa tttttattcg attttagata tgctataatg atcaagacag taaagtttgt
     3001 gacggtggct atccgattga aagtgaggtg gtgcgtatgt gcgtacttcc aaaatcttac
     3061 agaaaggaga agccttttgc ctgttgaaac ggcgctagga ttaatgatta gtttcggttc
     3121 tttgatcgca acaatcattt ttggaatctt agcagttgta aacaacaatc aaaaaaaata
     3181 accgtcagct ttagccggtc gacgattatt tttcaaaaat aatattaagc tggtcaccgt
     3241 cttaaacggt gctgttaggg gagttgttag cgcaactcct cttttcgtat ccattataac
     3301 aactttattg atcttttaca atcagaatgg taaatcatca tcactaatat cgattgattg
     3361 tccgccaaat ggattttgtg aagcgttcaa tccattgttg ttaggcgtag ctacatcccg
     3421 ttgttcaaag gtggtagggc ttggactgct ggacgattga tcagcgtgcg cacggctttc
     3481 tgtcgctgct ttactttcta atagttggaa attatcggcc acaacttctg tcacatacac
     3541 acgttgtcct tgttggttat cgtaggttcg ggtttgaatc cgtccaacaa cgccgatcaa
     3601 actgcccttt ttagctaatg tcgccatcgt ttctgctggt ttgcgccaaa tcacacagtt
     3661 aataaaatca gcttctcgat tgccgttttg attcgtgaaa tttcggttga cagctagggt
     3721 aaaagtcgct actgcagtac cactcgcggt ataacgtaaa tctggatctt tggttaagcg
     3781 tcctactaaa gttacattat tgatcatctt tatctctcca tttcttgatt catttgttgt
     3841 gatcttttaa actgccgttt tctttcttga ttttcaattt tgatcacact tttcattagg
     3901 tgatcaattt cgttgactgt atctgtaaat gaaatggaat tcgcaaacgt gttaactgag
     3961 cgatattttt cccactgctt ttccaaatag tcatttcctc tgatcttatc catttctctt
     4021 tcataataaa aggacaacgg ttttgtatcc ccacgttttg taaatgtatt tcgaacactt
     4081 ttgtataact ctttcgtatc gatattttct agtttcggaa tggtaaataa gtcgtagtaa
     4141 tcttttgctc tcgaattatc tgtgccaaag ctgaacgtag cacttagctt ttctgcaata
     4201 atttgttctg ttggataagc tggaatctcc acttttttat cttcaaacat taattggtga
     4261 tagtgtgtat ctacttcagg ataaatagaa tctcctgttg tcacgtccat tttaaacggt
     4321 acacgtactt tctctaaatt agccaccaat ttaatttgaa atccaggata aaaatcggct
     4381 tctcttgttt ccttcattcc ttgaatagag aaaacaatgc cttcttttgt gggttttcta
     4441 gttaaatcat taaaaatgct cttcaatttt tcttcagtta atttgctatt tctaaatgtc
     4501 gtatcgatat caattgttgt ccttctatcg attccatatt ttgatcctaa taaaaagccg
     4561 cctttcaaaa tgaagtcatt tttgtacttt gattcagaaa tttgttcaat tagacgatcc
     4621 atcataaaat gccgttgcac taactgtgca tttaatcctg tactctttgc taaatttctt
     4681 gtttttgctg caaattgtgt cggtgtcatc tttttcctcc atcaatataa gctttgcatg
     4741 tggtatttca tttctttttc tacatgtagt tttgtcatgt aatctcttaa tttacttgga
     4801 tctctcaatg ggtcttccat gtactctttt aatgcttcta atttcatttc atattcaaat
     4861 tcatatctcg gattccaaat atcacaaagt gtacgctctt tatcatacat agtaatagga
     4921 tttccttgaa aggaagttcc ctctactttt cctagttcat aaacttcttt cttcacgaaa
     4981 tgaaattgta actgctgctc ttttgtaatt gaacgatcaa cgttatagcc atggggaaaa
     5041 gttaagtgaa tgaatttcgg catattcgta gaaagctggt aaatatctaa agtcgtttca
     5101 tgagagaaga ttcccctgga aaatcgttgc tgaagccaaa ataaatcatc tattccatga
     5161 ccatcctcta cataataacc acgatcaact ttgatcaatt ttccttgatt caccaatctt
     5221 tgtacagtgg ttgctgcgat tccaaatttc ctggcttcct tcatagataa atttccatcg
     5281 cgaatagcca acaattcttt cagtttatct tgcatttact tcccctccct tcgttacaaa
     5341 tacactacat caaatatatc atagtagttt atttgtaaca agattaacgt ctatcgatct
     5401 aattcgattt ctttttgaat gcgctgctgg ttctttaatt gttgcagtct tcttttattt
     5461 gcacgtaatt tctcttgttc taaacgaatt tttgcttttt gattttcgat ttcttgttgt
     5521 ttgtgtgttg tatttcgcat aggataaccc cttcattatt ttgtagtgcg gcgtgttctt
     5581 ttcttatagt tcgttttttt cttttcagaa aattcaaagc ctgttgtaaa gtcttctttt
     5641 aaaacgatcg ttgcttcaaa cgaacctttc tgacctttta gtcctctgac tgattggctt
     5701 gttcggccgt tttgaatgat ctctttcagt tgtgtggctg tgagtttctt tttggcaatc
     5761 gttgtccata atttaaaatc acaggcttca gacgtacatg ccgccacatt ttgataaagc
     5821 aagacttctt gttcccgaca ttttggacaa acacctaaat gacgcgttgc ttcctgtttt
     5881 tcactggctg ctttcacctc ttgtaacgtt gatccaaaat ctgttgactg gatttgtccc
     5941 ggtacgactt ccaacaagtg agagacaaat ttttggatat tagctaagaa agtagcttgt
     6001 gttcctttct gctcaccaat ctttaataag taactttccc atttggcggt catttcggca
     6061 cttgttagca gcggctcttt ttccacggct tggcaaagta aaatcccttt atttgtcacc
     6121 acaagcttat ttttttctac cttgatatat tccttttgtt tcaaagtttc aataatattt
     6181 gctcgtgttg cttctgtacc gattccttct acttctttca atatggattg tgcttcttcg
     6241 ctatccacgg tttttccagc tgttttcatc gctgtgatca acgtaccttc ggtataaggt
     6301 tgtggtggct tcgtttcttt ttcaaggact tgtagatcta ccgtcaccgc ttctcctttt
     6361 gtcactttag gaagtagcgg ttcttcttcc ttttcttttc tgtcgctctc tttgccaaac
     6421 agctttttcc aacctagatc tactggtact tttccgactg tctttagctg aagctgctga
     6481 acttgcgtca agatcgttgt ttcttcatag gtatactttt ccgcaaacat ggccaccgtt
     6541 gtttttaaca cttgttcata aatagcctgc tgcagtggac ttaattgttc aaaagccgct
     6601 gccgtcatga ccgtctttgt aggaatgatc gcgtaatgtt cctggacttt cttattattc
     6661 acatatcgac tattcggtgt atgaatagga gtaggaatgg cttcggcctt taaaaagtgt
     6721 ttgtattcgt ctaagtgatc caacagatac gcatactccc cttctgtaat ataaggggta
     6781 tctgttcgtg ggtagcttag atatttccct tcatacaacc cttgcatggc ttccaaagta
     6841 tctttggcac tagctttcat gagctgattc attttagatt gaaggctgga tagagaaaaa
     6901 agacgtggac ttgccgcact ttttttctcg gtttcaactt ggtggatcgt acctggctgt
     6961 tttcccaatt gaaccccctt ttcttttaaa taatcttcaa atgcttcttg cgtcgcttgg
     7021 gtttcattcg gatcaagctt cgcatcaaat gcgccatttt gagcgattac ttgggctttt
     7081 ccttcaaaat atggttcttt ttggaagttt ctaatctttt cctgtaattg ataaatcatg
     7141 taaagcgttg gggtttggac tctgcctaag gaaaaacttc ctggtatgcc tttttgctgc
     7201 aagagtaaac tatacagcgg gctaccgttc atgccgatca accaatcggc gatctggcgt
     7261 gcttgtgctt cttcaaattt tgggtaggtc tcttctgcat ctcgtaactg ctggaatccc
     7321 tgataaatgg cttctttttc taaggagttg atccaaagtc ttttaaatat ctttccatga
     7381 tcggcgcctg cttgttgaat gatcgtccaa gctatcagtt ccccttcacg atcgctatct
     7441 gtcgcaataa taatggtgtc ggccgattga agttgctgtt tcaccacctt gaattgcttt
     7501 ttcttatctt taggaacatg atagtgataa tgtgtaggga aaataggcaa atgctctaat
     7561 gaccattgtt tccaattttc atcgtacata tcgggcgaat ctaactcgac taaatgacca
     7621 aaaccatacg tgatcacagt ttctcctgaa aacaatcgat cttggatctc aaaataccca
     7681 tcttttcggg tagctttaga aaagctatcg gcataagcct tcgcttgtga cggtttttct
     7741 gctaaaataa cggttttcat catgacgatt tcactccctt tcttgctgtc taccttgttg
     7801 aaacaacatg gcacgttttt gctttctgat ctcttgttgg tagatttcat gcttcaattg
     7861 atcattccaa tcctttttta cttcaggtac aaattcatgt tcatgatttt tatagccttt
     7921 gtagtattgt tctgctttat aagagaaaag aatctgagca ttaatatccc ctttttcttg
     7981 ataaaaacga tcaaaatcgt acgtaccatc cacgcgttca caagctttta attcttttgc
     8041 gacttctcta caaatatctt tcaaattaat agcttctatt gaatcgttaa cagaaagctg
     8101 ctgaccaaaa gacgcattta ctttgtgagc ggaaaccaat tggttcgtta attgcagatt
     8161 gttttctgtc ttgtgtatgg ccataatagc ttctggtgtg atcttttctt cttttgcgac
     8221 ttcttcataa atgactttgt attcttttgg cacttgccaa tcattagcga ttcctcgttc
     8281 acaacgtact ttctgattcg taaatggatc aactgcgccc attaattgtt ctttttcgta
     8341 gaaaatatgt cctgcacggt cattatccac acaaatctcg atggattgag gaaaggcttg
     8401 tttctttctc aattcagata ctgcctcacc aaaataatga ctgatcacat ggtgttttaa
     8461 cccttccatc gaaactaacc acgtatcgtt taactgatca cgatttagtg cagcatagct
     8521 aagtaaatca atactactct caaaaaattt taactgctta gggtcaccga tctttaggtt
     8581 aaagccatga ttcgctgtcg aatttttatc tatatgctta tatgtgcctc tctcaccaaa
     8641 acgttcataa tcaatgaacg ttccttgata actcgcccct actgtctcat ttgtctgtgg
     8701 atctttccat aaaaaggcga ccgcatgatc taaacgatcg tctcgaacta agaaattttg
     8761 ccgttcatgt tttggcttta gttcggcaat caacccttct ttttctgcat aatcaatcag
     8821 ccactctggt agttttcgtt cttccttcag ataattcctt cctttttctg tgagtggttg
     8881 ataatcaacg gggtgatctt tgtacttttc tgtctcaaaa tgaagatttt ccactcgttc
     8941 tgttttgtct tcattcttta gaataaaatc agtggctgct ttaaattgtt gcttagggtc
     9001 ttggatctct ttgtctatga aaaaaagttt agctaattca ataatgtcgc cactaatatt
     9061 ttgactgttc caataaaaac gttgttttct tcgatcaaaa acaaatgaat catggtcttc
     9121 taagcgatag tctcgtcctt tattgactac agccattcca ttgtttcgag caaaatccac
     9181 tatatcgatc tgtttacatc gatcaataag actcattttt ttctcggtca ttttaaaacc
     9241 tcccaaaaga aaaaagacta tccgtttttc agatagtctt ttttacttgt tttatacacg
     9301 ttctttttgt gacaattgtt gttcataata gatttcattt tttcgttttg ccacttctga
     9361 cactgtctca agtgaaaatc ggaatgaatt tcctagcgca aattcttctg aaggtaacgc
     9421 cgtttggatc tcttttccat aactttttcc ttttaaaatt acttgattat gctgtggatc
     9481 ttcaataaac gccgcatcct tcaaatgtaa cgttcgaccc gtatcttctt ccattacttt
     9541 cccgtctttc ttgtcgatcc aaagtgaacc aacaggaaca atattctttt gttctgccgt
     9601 ttctacagta tttttatgct cctgcttcac ttctgctggt tggatctctg gttctctttc
     9661 tctgtattga ttgatttcat tagaaatggt ttgaatgaat tcatttgcga cacggctgac
     9721 atcattcatg attttcccac gttccgcagc ttccttatca tccaacgtct gaccattctt
     9781 cgtccatgct gcaatataag gaatagcttt ctccgaagtg tccattccaa aatgtttgca
     9841 cacaatataa gaagtcattt ctgcctgcaa ttctttagtt gcggtatcta attctgaaaa
     9901 tttgtgcatt cttgcatggg ctaattcatg aatacttgta gctaaatgct gcgtaggagt
     9961 atttcgagta ttcatgacga tttcttcttc gccagtaaat tcgttacgaa catatgcccc
    10021 ccgtgcttgt cctaattctc tttgatagac ttcactttct gtcatatctc gaatttgtat
    10081 tccaatattg ttggctaccg cttgaatccc agcttgaagt tctgactgtc cttttttatc
    10141 caattgaaaa tcaaagacac ggttcggaaa gattttcgga tagtcttcag gttttaactg
    10201 tgtttgtgtg atatcaaaca ctttttcaat cgtgtagtaa ggttttttga tcacttcgat
    10261 ttgaccactt tcgattcgtt ttttatcttc tggtgtagct tctgtttctc gaacaaagcc
    10321 acgtcctttc tcataaaatc ctttgaccgt ttttctgaca aagatcttgt tcccttgttc
    10381 cccttttttg atatagattc cttctttttt caacgcagca cgacctaaac aagccgttgc
    10441 acctggaaat tgttcctcaa tcaataattg atttctaaag gatcgttctg gaaaacgaga
    10501 cataaaattc aaaagttctt tcacgtcttc aggagaatgg gtatgctttt tcaccgcatc
    10561 cagtgcctgt tgcgaaaggg atttgacttc ttgcttaatc tcttctgccg ttcgtttttg
    10621 atagcccttt tgttttgttt ttgtttcttt cgactgcatt tgttctttcg aaacaggttc
    10681 atttttgacc gtttgttttt gttccttttc aggtacttgt tcgcacaatt ttgctaactc
    10741 taaatagatg ggttgattac tgttgacgcc atcccctaga tccattcgga tctgatcgac
    10801 tacttctccg ttcttcactt cttcaaaata gaatttataa taacctgctt ctgcggcgta
    10861 ttggttatcc aacgttttga gttgatcgat caattctaat gttacgatct ccccaccata
    10921 acttttcaat cctttttctg gatcattttc gttgaattct actcgataga aatgatcgtt
    10981 ttctttctcc ttcaaagaat cagttggcgc agcctcttca agtaattcac gaacagctgc
    11041 tttttcctct tccgacgtgg cttggtattt ttttgattcc tcaaatcccc cgttttcatt
    11101 cagttctaaa gcaacttttc gatagtcttt caaaaaataa atggttggat tttttttcca
    11161 ttgcgtcact cgtccgctgt caataattgc ttgtacttca ggaagaagat tttcttttcc
    11221 tttttctgat ctttctttca gctgttctaa tgtttccaat ttccgttggt attttcggat
    11281 cgtagcggct gaaaaagtcg attcaccttt ttcaaagcgt tcgatttctt ctttgattct
    11341 tggaatattt tcgattgtca tatccaggcc gccgtacttg ttatagccca tttcctttag
    11401 ctcttcttgt ctttcaagtt tttctacctg tttttcttgt tgcttgatct cttctctcag
    11461 actatgcact ttgttttcta aacgttcttg ttgcctaaac caagaatgcc catttctctt
    11521 atcgttcatt ggctgaccgt tggtctttct ctggtgttca aacatcttct caatttgttc
    11581 gtttaattca ttttgcaatc gtactaattt tcttttggat tttcccaagc gactattgtc
    11641 tagtggttct ttttcttctg ccatgtc
//
LOCUS       DACGDM010000079        11644 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.084, whole genome shotgun sequence.
ACCESSION   DACGDM010000079 DACGDM010000000
VERSION     DACGDM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.084"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            317..676
                     /locus_tag="IXR05_002179"
                     /pseudo
     CDS             317..676
                     /locus_tag="IXR05_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(971..2104)
                     /locus_tag="IXR05_002180"
     CDS             complement(971..2104)
                     /locus_tag="IXR05_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4260661.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            complement(2095..2763)
                     /locus_tag="IXR05_002181"
     CDS             complement(2095..2763)
                     /locus_tag="IXR05_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260662.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(3219..4205)
                     /gene="lacD"
                     /locus_tag="IXR05_002182"
     CDS             complement(3219..4205)
                     /gene="lacD"
                     /locus_tag="IXR05_002182"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4260663.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(4218..5144)
                     /gene="lacC"
                     /locus_tag="IXR05_002183"
     CDS             complement(4218..5144)
                     /gene="lacC"
                     /locus_tag="IXR05_002183"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HAQ4260664.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(5157..5672)
                     /gene="lacB"
                     /locus_tag="IXR05_002184"
     CDS             complement(5157..5672)
                     /gene="lacB"
                     /locus_tag="IXR05_002184"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HAQ4260665.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(5691..6119)
                     /gene="lacA"
                     /locus_tag="IXR05_002185"
     CDS             complement(5691..6119)
                     /gene="lacA"
                     /locus_tag="IXR05_002185"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HAQ4260666.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(6139..6912)
                     /locus_tag="IXR05_002186"
     CDS             complement(6139..6912)
                     /locus_tag="IXR05_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4260667.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            7077..7556
                     /locus_tag="IXR05_002187"
     CDS             7077..7556
                     /locus_tag="IXR05_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4260668.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            7613..7915
                     /locus_tag="IXR05_002188"
     CDS             7613..7915
                     /locus_tag="IXR05_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAQ4260669.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            7937..9394
                     /locus_tag="IXR05_002189"
     CDS             7937..9394
                     /locus_tag="IXR05_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol transporter subunit IIA"
                     /protein_id="HAQ4260670.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(9987..10739)
                     /locus_tag="IXR05_002190"
     CDS             complement(9987..10739)
                     /locus_tag="IXR05_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4260671.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(10954..11190)
                     /locus_tag="IXR05_002191"
                     /pseudo
     CDS             complement(10954..11190)
                     /locus_tag="IXR05_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
     gene            complement(11200..>11644)
                     /locus_tag="IXR05_002192"
     CDS             complement(11200..>11644)
                     /locus_tag="IXR05_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4260672.1"
                     /translation="HKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHL
                     FKSMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDF
                     RDMDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
BASE COUNT         3343 a         2510 c         1994 g         3797 t
ORIGIN      
        1 ttataaataa ctcataaaaa atattttgac tttcaaaatc acttttgcta ccagaagttg
       61 aggcgaagtg ttttaagcat agttgtaccc tagtttgacc gttaaaaata aataacgatc
      121 gctagagtgc aactatgttt gtttgcccta ccgtcagcgt cggcttggcc tctcacatcc
      181 attaccgtcg ggattatctc cgttacatac ccttacaaaa tacgccctgt aagcattgca
      241 tgaaaccacc gtgcatttgc accgtatttc cgccctagcc gttcaaatcg gtcgctacca
      301 ccattcagaa acacgtgcgg taatggaagg tttggaggaa gctatccaga ccactaacga
      361 ttgtccctat cgtcgtacgt ttcactcaga tcaaggttgg tcgtatcaaa tgaaagctta
      421 tagaaacaaa ttgaaggagt acaaaatctt tcaaagcatg tctcggaaag ggaactgctt
      481 agataattca cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa
      541 agtttataac tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa
      601 taatgaacgg ataaaacaga aattaaactg gcaaagtccc gtccaatttc gtaaaacaac
      661 cgttacggtt gtgtaaaaat atcattttag agcatgaaaa aaagagtgga tttctccact
      721 ccaaaaaagt ctaacttttg ggggtcacta catttttgat cctttttatt tgattaatta
      781 tatccagctg gataataatt ttgggggcaa catttctatc ttactattat cttcctaaag
      841 tagtagactt tcttattggg aaaaattaca acaaaaagga gtggcttagt tgacaactcc
      901 tttttgttta caaatcaatt ggatatctat aaattgtatt ttctaacgaa ttttatagac
      961 atctgatttg tcaaattaag ctagacaata tgtctttatc tatgcagctc aaaaatactt
     1021 ccaatggtgt tcgataattt aatgattttc ttggaatatg gtttcttttc gaggcaacgg
     1081 attgaataaa ggtttcatcc gtgtccctaa agtccattgt tttaggtaag ccatcctgct
     1141 tgagcccatg cactcggtac tgatgagaaa aaattgatgc ctgtttctcc tgaggaatgc
     1201 caattccctg atcttttact tcaataatca cgctaccctt ttggtttgaa atggtgacaa
     1261 ttaccagttt tccttcacca tatttgattg cattgtcaac taaattcgaa accgcccgat
     1321 aaatccaacg atctcgtcca tgaatcaggg ttggttgatc ttcagtaaac gcaaacaaaa
     1381 gattcggata attcattttg taggcatcac aaacttccgc acagatcagt gaaacgtcta
     1441 cgacttccgt gctaagatcc tctgagttat tggataatgt caaaatatcg tcaatactgt
     1501 cggtcatccg atctaaaagc attaaatttc cttgatcggc atgttgccgt tctatttcca
     1561 gattcgtacg caaaatagcg atggcatttt tctgctcgtg ggtcagataa ctatttaatc
     1621 gtcgataatc ctccaaatga ccatcgaact tatcctttag cttattaaaa gccgcattta
     1681 atgcctcgtc cttcacagta tttttaggaa cttgatcaat aaacgttaaa tcacgcgtaa
     1741 tcgctaagat ttgattactg taaattttgc gtaaaaccaa ccaaagaata aacgttaata
     1801 acatgacggc agaacaaata accagcacca tcgctggtaa atatttaaat agttcgtcct
     1861 ggtaagcttt atctatcatc gaaatagtca taaattgatt gttggaagat ttcgaagctt
     1921 ccatctgcgt ctctgcttga accgtcttac cctcttccat aaaataaaca tcttcaccta
     1981 aggtagatgc gatactgatt ccctccaaat tatttctcag aaagaagaaa ctcactaaaa
     2041 tcacgcctgt caccaacagt gaaaaagcca gcatcgttaa cgtcatttta aaatttaata
     2101 gcatagctgg tacccctttg ctcgaatggt ttttaagacc tctttttcag ctgcttcagc
     2161 cagtttcttt tttagacgag ccagatgcac tcgcagaacc gacgaaaaag gatcaaaatc
     2221 ttcatcgtag acatgttcag aaatttcctc agacgaaaca accgctggat gacgctgagc
     2281 gatgcacagt aagatatcaa attccttggg tttcaggacc acctctgtct tttgatagct
     2341 gacccttcga cctaatggat caatcttcaa agcaccaatt gaaatctgcg gcagcgcacg
     2401 tccatgataa cgacgaataa ccgcgcgtat tcgtgctttt aattctagta actcaaaggg
     2461 tttgactaaa taatcatctg ctccaaaatc caagcctttt gctcgttctt caatctcatc
     2521 acgtgcagta ataatgataa ctggactttc gacttcttca gcacggagac tttgtaaaac
     2581 agataatcca tcttttttag gcagatttaa atctagtagt atcccatcgt atgaattgat
     2641 gaaggccttc tcttctcctg actcgccatc ataagctaca tctacagaaa tattctcctg
     2701 ctctaggccc ttttttacgg ataaaaccag ctcacgattg tcctcaacca ccagtacacg
     2761 catgtatatt cactcctcat acggatttag taattacact tatgcttttt agcatagtac
     2821 acgctcttct tcaaagtcca cgttcttttt gtgaagattt gaagaaattc atacattctg
     2881 ttaaaaaaca cataattaag aatgatttta ctgtttgaaa atacctagaa tagaaaaaga
     2941 ctggaacctt tcctccagtc tcactacttt ctatttgctt ggttttcttg tatatacttt
     3001 tcaaagttcg ttggtttatg accaataagc ctcgttagaa tactgaaaat tgccatcaag
     3061 tcattaagta ccacatgtaa gaaaatctct ctaaagaaaa accccttcgt tttaactcac
     3121 ttactatttt agaattcgtt cccctaataa tgcagcatga ttttacgctt tatgtataaa
     3181 aaaagactgc aagcaatttt gcttcacagt ctgatttctt atgatagtga gcttgttaac
     3241 acttccaccg gtgtagcagt ttctttcaat acggcattta attcttcaat atttttacgc
     3301 ccttgcgtat tcatccactc catcgctgct tcttttccat caacgatata gctttctaca
     3361 ccatctgccc aagtcgcacg gccgcaaagt acaccattga aggttgagcc ggcatttttc
     3421 gcgaagcgca gtgtttcttg gaacaactct gcttttacac cggcgcttag gaaaataaat
     3481 ggcaggttag tggcttcagc ctgttccttg aagaagttag ccgcttgtgc ctttgtgtac
     3541 acgacttcgt ctgtcccata gccttccaca taattcatat tgacgggtac ttccaccttt
     3601 aacacatcta cgccataacg tggatcagaa aattccttca tcatatcgtt gactttatga
     3661 ggtttcttaa tggcgtattc tttcgaagtc gcatcagaga tgttcgcgtc ataagaaaca
     3721 agctccaaga agaagggtaa gttttcagcc tgacattctg agccgattcg ttcaataaag
     3781 gcatgttttt gattattgat ttcttctgct tcatcgacat catagtaaag taggaactta
     3841 caagcatcgg cgcctgcttc ttttaaacgt ttaactgacc agatcgataa taaatctggt
     3901 aaacggccgg gagttgacgc atcgtaacca gttttttcat aagctaacag caagccggca
     3961 ttttttgctc taacgtcagc tgctggcaag ccatattcgg gatctaataa aatcgatgag
     4021 gcatatttcg ttaattgtga agaaacaatt tctttaaatt caacgatttc tgattcttct
     4081 gcttcgctgc ccttgaattt tgtgatcatc ttcttcaaag ccccgcgttg atcaattgct
     4141 aaggccccaa tcactccatc ttcattgcat agttgcttga tatattgacg tttttcttcg
     4201 ttcatttccg tatcctccta cactttctcc actaagattt gatcatatag tttttgataa
     4261 ttggctaatt ggacatagcc agtcgtcgct tcctgagcat tcagcattcc taaaacatta
     4321 ccctgtttta acacggcttc atccgaaaga ccttgttgaa tcgcagcggt caatccggca
     4381 acggtcgcat caccagagcc aactggattg acgacatcaa tctttggaat tgtcacgcaa
     4441 taaaaagtct cgtgatgttt ggcaaaggct ccgtcgcccc ccattgaaac cactatccat
     4501 tcaatttcat caaacatcga atctgacaag gcggctttta aatctgataa ttctgttgag
     4561 atttctcgtc ctagcagacc agccagctct tcggtattgg gttttattag cttaggcttt
     4621 acactgcctc gcaacacttc ccttaatgct gtacctgaac aatctaaaac gacaggcttt
     4681 ggctgacaaa cttgcagcat ttgtcgataa aaatcagcag gcaatccttc tggcaagctt
     4741 cctgaaaaag aaatgatttc ggctttaaca gctaattttt cgaaatgttg caagaacgcc
     4801 cttgcttctt gttcagtaat aacaggtccg ttttctagga tttccgtctg ttttccgtca
     4861 tgtaaaacag cgatgcaatt acgtgtctct ccgctgatag gtaaaaagtc atgagcaatc
     4921 tcattttgag tcaggtcctt tttaatctct tcacctaaaa aaccgccgat taaaccacta
     4981 gcaatcacct ccgtatctaa ttgcttcaag atacgtgtca catttaggcc cttaccgcca
     5041 gctgttttgc gaacatttct tactcgattg actgtgtcga gcttgaaggt ttctaatgga
     5101 taagaaatat caatcgatgg attcatcgtt attgttaaaa tcatttgtcc acccgcttaa
     5161 tcgtggtatt cgccacgatc ccatttctcg ataaattcat cgaagaaatg cggatcagac
     5221 tgcttgtcac tggctttttc gacgtgatcg attttggcga tcaatttttt gttttcttca
     5281 gtttcttgat aatcggcatt gatgaaggcc tctaatatgt cacagatcaa aaattctccc
     5341 gtaatccgag cgccaaagcc gatcacattg gcatttagtt gttccttcgc atagatagca
     5401 gtcgtcatat cgcgaaccag cgcactgcgg ataccaggta ctttattgac agcgttgtta
     5461 atcccaacac ctgttccaca caaacaaact cctagatctg cttctccgct agtcacggcc
     5521 tctccgactt tttttccgta gatcggataa tgggttctgg taaagtcata ggtccccata
     5581 tccaacactt catgtccttt tgattttaag aaatctgata ctgccatttt tgtatctgtg
     5641 acgatgtggt cacagccaat tgcgattttc atttcattca tccttcctaa ttacgccatt
     5701 ttatttaaca tgtcgacacg tacttgatga cgaccaccat cataatttgc ttgtagaaat
     5761 tccttaacaa tattcaacgc caactcatcg ccaacaattt ttgatccaag tgtgatcatc
     5821 cgagaattat tatgtttacg ggtcatatac gcactgcgct catccgaaac ttctgctgct
     5881 accattcctt taacctttgt tgccgtgata aagctgccag cgccgtagcc atcaaccgcg
     5941 attcctaaac taccttcgtt ttcattcaga tcatttgcga tcgccaaagt tgattccaca
     6001 aaatcttctg aagccgtttc actcttatct actactgtaa taccttcttt gatcaatttt
     6061 ttcttgatta attcctttaa ttccatgccg tcactgtctg aaccaattac tacacgcatt
     6121 tttgtttcct cctatttttt actgaatgat tttagtgaat tgctgataat aactcttcag
     6181 ctcggctgaa agagtagaat ccgtaaataa tttgtcgatc ttgcgcaaat catagaaatt
     6241 ataaaaatcg ctatggtcga atttgtttgc atctgaaacc aaacattttt ctgccgcatt
     6301 atctaaaaca attttttgca aggtaccttc ttcaatactg aaattcgaaa cctccgaacc
     6361 cttcaatcca ttcactccga caaaagcctt cttaataccg attttttgaa cagcttcatt
     6421 ggcaattgaa ccgacaaagg ctccagtctt ttcccgatat agcccaccga tcaaatacag
     6481 ttcaaatctt tttatttcac ttaatagatt gaaaaccggc agactattgg taacgattcg
     6541 gagagatgac ggcttgatgt atcgtgtcat taattcgatc gttgtacccg atccaagaaa
     6601 aatcgtgtcg tcttcttgat tgatatgagc tgccgcattt ttagcgatgt attccttctc
     6661 ttttgtatgc agcttctttt tttcagtatg agaaagctca tttgcttcta tagaagtcga
     6721 catttccaga taatcgattt tttgtgcacc gccatgaacg cgtaaaagct ttttcttctg
     6781 cgcgagttcc tctagatctc ggcggatcgt catatctgaa acattcagta cttcctgaat
     6841 aaatttgact gttatcgtcc catagcgatc acacatcgct aagatcgaac gctgtcgttc
     6901 tgttttcagc atattctgta cctccacgac cttataataa aacatttacg aacatttttc
     6961 aacacatatt gttcgtttat tttcgtttat gcgttgacaa tgattttgta agcggttata
     7021 ctcaacttgt aaacatataa ataaacataa acgaactaat aaaggagctg ttttgtgtga
     7081 atgaattctt tttcaaagac actgtctatg tttctgacaa gcagtcgcag gaagaagtgt
     7141 tcgaggaagt ctatcaagat ctgttaaaga aagaattggt aaccgaagat tttttggaga
     7201 accttttaga acgggagcgt aattatccga cgggattaga tctctcacct gtctctaaaa
     7261 tattgccaga tatcgctatc cctcataccg aaagtgagtt tgtgcgaacc acccgtatca
     7321 ttccaatcaa agtaaaaaat gaaatccctt tctacaacat gatctcgcca agcgatcaga
     7381 tttccgcttc atttcttttc atgatcttga acgaaaatgg tgaagcacag gctggcatgt
     7441 tggctaatat catggatttc attaattctg ttgacgaaga aaaactgttt tcgtttttca
     7501 aattagagga cacagaagcg atttatcatt ttttagaaga acatttttat atatagaagt
     7561 ctctgcctaa ccgcaggata aaaaataaac ttattttaag gggagaatta ttatgatcaa
     7621 aattttagca gcatgtggag caggcgttaa ttcaagccat caaatcaaaa gcgctttgga
     7681 aactgaattg aaaaatcgtg gctatcaagt cacctgtgac gccgttatga tcaaagatat
     7741 caatgaagaa atgctgtctc attatgacat tttcgcacaa attgccaaca ccgacttggg
     7801 ttttgacatt aacatccctg tcgttgatgc aggtgctatt ctttatcgta ttcctgctat
     7861 ggctgagcct gtttaccaaa gtatggaaag cgcaatccaa tcattaaaca aataggacta
     7921 aagaaaggaa aagcatatga atacaattat tgatattgcc aataaagtat ttacccccct
     7981 aattaattta ggtgcggcac cgttaatgac catcgtatta actgttattg ctttattttt
     8041 taaagtaaaa ccgtcacgcg ctcttgaagg cgggctcaaa ttagggatcg ccctgactgg
     8101 gatcggagct attattggaa ttttaactac tgctttttca gacgctatga cagcttttgt
     8161 tgaacgcaca ggtatttcat taaacattac agatgtcggt tgggccccac tagcaaccat
     8221 cacatggggg tcgccataca cgctttattt tttactaatt atggtgatcg tcaatattgt
     8281 catgttagca atgaaaaaaa ccaacacatt agatgtggat attttcgata tttggcattt
     8341 agcaattgtt ggtttgttcg cgatcttctg cggtgctaat ctgtttattg cttctgcatt
     8401 agttattttc attggtgtat taaaaatttg gaactccgac ttaatgaaac caaccttcaa
     8461 tgacttgtta aatgcgccag acagcaaccc gatgaccacg actcatatga actacatgat
     8521 gaatccgatt attatggttt tcgataaaat tttcgacaaa atcttccctt ggttggataa
     8581 atatgatttc gatgctgcca aattgaatag taaaattggc ttctggggat caaaattcgc
     8641 gattggaatt tatttgggga tttttgttgg attactagca ggacaaacac caacgcaaat
     8701 tttctcgcta gcctttaccg ctgccgtctg tttggaattg ttctctttga taggcgcttg
     8761 gttcatcgca gccgtagaac cgttatcaca agggattacc gattttgcca ataaacgact
     8821 aaaaggacgt accatcaaca taggtttaga ctggcctttc atagcaggcc gcgctgaaat
     8881 ctgggctgcc gctaacgtat tagcaccaat catgttgcta gaagccatca tcttaccagg
     8941 aaataaatta ttgccactag gcggaatcat cgcaatgggt gttaccccag cactattggt
     9001 cgtaactcgt ggaaaattaa tccgtatgat cgtaatcggc gcgatcgaat taccattatt
     9061 cttatggtcc ggcaccttga tcgccccgtt cgttactcaa acagctaaag cagtcggagc
     9121 ctttccagcc ggcttgaacg ggtccgccat gatctctcat acaacgatgg aaggcccgat
     9181 tgaaaaattc ctaggttatt tagtcggtaa tgcttctcaa ggacaaatcg aatttgtgat
     9241 atacgctgcc ttagcattag gtgcatacct tttaatcttc atttggtacg ctcgtcaaat
     9301 gaaaaaacgc aacgctgcat acgcagctga aaaagaagag aatgcatctc cggcaacggc
     9361 gcataatatg acttatgcag ccgaagctaa ataagctaaa aacaccccga atgtctttag
     9421 acttcggggt attattttac ctataaaaaa taaatagatg taaaatccat ttcaaaaagc
     9481 atagcccatc tcttgccaca cccaataaag aaattatcaa cgtttatgct ttttttaact
     9541 cctttaagct tgcctttgtt ggtattcctc aacgattctt tttgtgttct tgtttgtttt
     9601 gtgctttttg actttttgtt gtttaattgc gaattccttg atttcttttt tcctgaatcg
     9661 cttcgcatcc cgcggttatg cgtgcgattt catcattgct ttttctgatc taactcgttt
     9721 catgtcaaag agcttcagct gacttagtgt ccatggttgt tttgatatcc cttttcctcc
     9781 ttaataaagc ggtgattgat actgctattt tttccttcac ataaacataa catcccaaaa
     9841 aaatcgacta tcttttttca aatggtgtat tcaagtattc ggaggaatta gtaatgatgc
     9901 accctaaaaa taacataatt cgcttaaatt caaggctacc aaaaaactac caagttctaa
     9961 ttatctagag tttggcagtt tctcatttac acaacatatt tttcttcttt ttcgattttt
    10021 tcatagtgct tttgttcatc atcatccgtt ataactactg ttacatcatt cagattataa
    10081 tatactgaaa aatctctttt cccaattttc gaatgatcaa tcaataaaaa gcgttcaaca
    10141 gaattattca gagcgatctg ttgagtttgg ccctcttcaa aagtcgaagt cataattttc
    10201 tgttcattta aagcattaca gctgaaaaat gctttatgaa aattcatatc ctgtagcgat
    10261 ttattcgtga tttcaccaac aaagcattga gtcgtttccc gcatctcgcc acctaataga
    10321 tagatttttc gattcccttt tcgcttattt aattcttcaa aaacaggcaa acagtttgta
    10381 acaatccgca gtgaatcccc ttgaatgatt tttgacatga gctcgattgt agttcctggt
    10441 ccaagaaata tcgtatcacc atcattgatc atttcattcg ccttttccac aatccgctgc
    10501 ttttcttctt gcagcataat ctgtttttct ctatgagaaa gctccacatg ccgataaaaa
    10561 tccttcaatt tcgctccgcc atggacgcgt tctaataatc cttgtttctc catttcgtcc
    10621 aaatcacgtc ggactgtcat atccgaaacc gaaaacttct ccataatatc gctgactcgt
    10681 actgtaccgt taacctctaa taacgacatg atcgcttgga atcgatccgt ttttaacatt
    10741 tcatcgcctc ttttcttttt aagactatca aattcttaag aaaagtgcta gaacaagttt
    10801 tcttaagaag ccttctgcag gaaggaaagc aaaatttttc agaatttgca agctgctatt
    10861 ctaaaaaata aaaccgaacg agcatgactg tcatagtgac agccttgttc attcgacttt
    10921 tatctttaat aaatcatttt atttaatctg aagttattgt gcaagttcaa aaacaaagta
    10981 gttaatgtct cctcgatatt tcgaaatcga atactcaacg ggcagacgtt ctagcgaaaa
    11041 accctgtgta tggaaataga acattggatc tccttcttcc acatctaaca aatcgctgat
    11101 cgtatcatcc gctttgatta cttctagttt tctggtgacc gttttaattg gataacccat
    11161 ttcttcaaaa acttgataca ttttttcttt tctgatttgt caaattaagc tagacaatat
    11221 gtctttatct atgcagctca aaaatacttc caatggtgtt cgataattta atgattttct
    11281 tggaatatgg tttcttttcg aggcaacgga ttgaataaag gtttcatcca tgtccctaaa
    11341 gtccattgtt ttaggtaagc catctcgtct aagcaagccg tttgagtgct catttagccc
    11401 tctttgcgaa ggtgttcctg gatctgcgaa aaagatggca atatcgttcg agttacttat
    11461 agatcgccag ttggaaaatt cttttccaca atcaaatgtc atggatttaa acaagtgttt
    11521 aggcatggat ttgaaccaat catttaacct gttttcgata tcttcggctc gtctgcctgt
    11581 cggtttcaaa gtaataataa ccttggataa acactcaacc aatgtaataa cagcgctctt
    11641 gtgt
//
LOCUS       DACGDM010000080        11609 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.085, whole genome shotgun sequence.
ACCESSION   DACGDM010000080 DACGDM010000000
VERSION     DACGDM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.085"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            6..305
                     /locus_tag="IXR05_002193"
     CDS             6..305
                     /locus_tag="IXR05_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4260673.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IXR05_002194"
     CDS             378..1739
                     /locus_tag="IXR05_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAQ4260674.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IXR05_002195"
     CDS             1761..2021
                     /locus_tag="IXR05_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260675.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IXR05_002196"
     CDS             2035..2787
                     /locus_tag="IXR05_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAQ4260676.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IXR05_002197"
     CDS             complement(2881..3486)
                     /locus_tag="IXR05_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4260677.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="IXR05_002198"
     CDS             complement(3539..4513)
                     /locus_tag="IXR05_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAQ4260678.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="IXR05_002199"
     CDS             complement(4891..5670)
                     /locus_tag="IXR05_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4260679.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IXR05_002200"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IXR05_002200"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4260680.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="IXR05_002201"
     CDS             7161..8558
                     /locus_tag="IXR05_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4260681.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="IXR05_002202"
     CDS             8639..9079
                     /locus_tag="IXR05_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4260682.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="IXR05_002203"
     CDS             9227..9553
                     /locus_tag="IXR05_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4260683.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="IXR05_002204"
     CDS             9554..10303
                     /locus_tag="IXR05_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260684.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="IXR05_002205"
     CDS             complement(10383..10838)
                     /locus_tag="IXR05_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4260685.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="IXR05_002206"
     CDS             complement(11265..11540)
                     /locus_tag="IXR05_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260686.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT         3666 a         2014 c         2359 g         3570 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagg
//
LOCUS       DACGDM010000081        11603 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.086, whole genome shotgun sequence.
ACCESSION   DACGDM010000081 DACGDM010000000
VERSION     DACGDM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.086"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(153..1616)
                     /locus_tag="IXR05_002207"
     CDS             complement(153..1616)
                     /locus_tag="IXR05_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4260687.1"
                     /translation="MKKTSKCLSALLLVGQVFGYTPAVLANEQGNNQLTNSQSATITE
                     ETTTNSTGEENQPETPTEDTIDTPDNPEMNAPPTGSEEQPETPNQPDKPEDNQQPEEE
                     PSEEPNEQPSDESSQTPQKPSTETEAEPPTKTERPQKAPEQSVTVPMNDVPQAQSIGS
                     EETKNYHQAPSAPIQELVPSSTQDNEGTIHFEKDASVETFIRKIGESARKIGQENDLY
                     ASVMIAQAILESASGQSQLAQAPNYNLFGIKGTHNGKGVSFATQEDLGNGTLYTTQAT
                     FRQYESYEESLKDYAKLLKEGLVGNTSFYDGVWKSKAKTYQEATKFLTGRYATDTSYD
                     KKLNGLIETYDLIKYDKEVAGPQLSKEGYMVPLKNYSISSSFGWRGEEFHRGLDMAAN
                     QGEPIYASKAGTVIEASYHTLSGNYVTIEHEDGSVALYAHQQEYCVNVGQTVEQGQII
                     GYVGSTGNSTGPHLHLELALDGSLTKDKLINPETVLF"
     gene            complement(1680..4697)
                     /locus_tag="IXR05_002208"
     CDS             complement(1680..4697)
                     /locus_tag="IXR05_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4260688.1"
                     /translation="MFKRMATWLAIFVTFLNPMLGSVTAFAETINESNSTEEVMKTEE
                     SKSSEEAISTETTSETTEETTTQDTTEDVSPPNVMTQEVPEGYEKYFITIEDIQKATS
                     FSEQERLAQESEEWQAILEKNAQTRATNLTLTENGRKDVNMTRITPEGTMYTHDYMVR
                     WQIDGEDVFCIQEGAITSAGIQYDVTPLENLITTSAIRKKISLIGYFGYYSSGSMDNY
                     VLAQTYIWEVLGGSFVNYGTIGQSNYEAFKQTVDRKINNLLEDPSFDSQTVTVKVGEE
                     VEVKDTKGVFSQWDGSVVENTANVQVRKSGNSLFIKANQNSNDGRISVSSLDPNSRGV
                     GSSFAYVDPVAQNLGKLYVPDPNRAGLTIKVLKNGDFKLTKLDAVTGKKVPNVTYEIK
                     RHDTGETKQYTTDAKGEIALKEIPAFYEKDGKYVQNKLDVKEVKAPAGYILDKQTHTI
                     TIEPNKEVTLTAKNDLQQFIPEGKKVKEVYNAEESWNQGKPVYDTVPAENIEFDIIAK
                     TDITAPDKETVLVKKGEVLDSVKTDKDGHWKANKKFYNGDQNKYQLIEKNVPDNYRQP
                     SEEQTTFSVAYGDNTTPVLTFELDVIDNLLKTGEVDFNKVDSINHLQLPGAKFLIEGM
                     TAHNKNVSFVYETKEEPEKLKLPDGTYKFTEIVFPEHYGQASGQTETILVTVKDGEVQ
                     PITVKNEEIVVPEEDQPEISTLFVTTTGGKDFNPKKDQELVDKVSQVFPKSAVGTEKY
                     WVTQFHKITADGKVTVLDTVKETRKVTDEKETFDVTFNYKADMVSDGDTIVATHIVYN
                     DKEEEEEFARHFDLTNKDQTVTAKEPKIETRFITVNGDQTFDPDKDQELIDHVSQEFP
                     ESTVGETKYWVTQFHKIDKNGKDTVVGTVETARKVSKASEEFKVSFDYKAGTLKDGEK
                     LVATHIVYKDKDHKEEEARHFDLKNEKQTLTAKGIKKETPTTPVKQTPTSTPKQSLPK
                     TGETVNDVLIALGLFLFVGVGAVLVRRKMKQSN"
     gene            complement(4848..5687)
                     /locus_tag="IXR05_002209"
     CDS             complement(4848..5687)
                     /locus_tag="IXR05_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4260689.1"
                     /translation="MKMLKVLALGIVVGGVSLAVGTNAEAAENKVWTPRSAEQIKAEI
                     KGNEYTIVWGDTLSAISQATNITVQKLADMNKITNVDLIYAGNKLVFNGNVASVQNSA
                     GETVAQTVIQEKDKVDPNQPVGQGTTSNTQTTPNTTTPTTPAGDQTGTTGGTTTPSTP
                     ENNGGTTQTPTQPGNGGNTGGETTPSNPSTGGGTTTPEEPSNPGGGDQGGNGGTTTPE
                     EPTIVVGEIGNSGKVFNTVDEAYDWANAEVSDPNSQWYNKGFMVDVIIYSDGSQKHTV
                     DFY"
     gene            5832..6077
                     /locus_tag="IXR05_002210"
     CDS             5832..6077
                     /locus_tag="IXR05_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014862476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260690.1"
                     /translation="MQLNNLNEIHDWAQNNLLNRKQAAKITGQNYDAFSSSLRRNNIK
                     PFLEIGDEPGPSIIRLYLREDIEKYAKQLEEKRQKRQ"
     gene            6140..6562
                     /locus_tag="IXR05_002211"
     CDS             6140..6562
                     /locus_tag="IXR05_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014862359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260691.1"
                     /translation="MNKKYIVSVGSIVLIVLAIIAFSVSNKTETQPQNTVQSTTTSQS
                     SDHSVYPSLNSLKETHGQDLIDLGSSQITTVLFEKKNIAFITPKEGTDLEFSIKVTNT
                     KENLFSIPDIQYTPNKLKIGDTFGLAKVNEQYFAYSLK"
     gene            complement(6656..6973)
                     /locus_tag="IXR05_002212"
     CDS             complement(6656..6973)
                     /locus_tag="IXR05_002212"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260692.1"
                     /translation="MPVKGTSNFDFEIFYVDDEICGVFNKQKYTKEQAIEAWKNELFD
                     PEEEISFVVDESFVGWYHGNAEEEEVHYAGWWLEEGEPREQSVPVWVISENPLEEIEK
                     LEK"
     gene            complement(7000..7206)
                     /locus_tag="IXR05_002213"
     CDS             complement(7000..7206)
                     /locus_tag="IXR05_002213"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260693.1"
                     /translation="MNWLKNEAELYVFHEEMQEKHLVPNVRNYLFWLEEKNDAQVFGK
                     SAQSPKIKLQLTSKQWNEHEWYIY"
     gene            complement(7187..7369)
                     /locus_tag="IXR05_002214"
     CDS             complement(7187..7369)
                     /locus_tag="IXR05_002214"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260694.1"
                     /translation="MTKCERVSVTISFIALLLSVISLLNTAIFIGQVEKQKEISLSEW
                     RYEEVNEGMNNELVEK"
     gene            complement(7383..7733)
                     /locus_tag="IXR05_002215"
     CDS             complement(7383..7733)
                     /locus_tag="IXR05_002215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260695.1"
                     /translation="MKKSYKVFENNEIKEQEAIILSAQTPEEALEQALPFLVESQNIV
                     VEELPEFDSKIVFSFNCKKESEISVSPEFYCRSDISVEGLVMCASAFIEIFANHLQIS
                     VKELLDLLQEITNE"
     gene            complement(7759..8061)
                     /locus_tag="IXR05_002216"
     CDS             complement(7759..8061)
                     /locus_tag="IXR05_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260696.1"
                     /translation="MLSKQEKKYIRQKMYAMIGNRAITELSSEELLQVQQLAQIIGSN
                     SIFDSNPLPEMTLETLTAKRYKELRAIGYRMIDIRRALRISDTKFREWRTSNGLAN"
     gene            complement(8064..8297)
                     /locus_tag="IXR05_002217"
     CDS             complement(8064..8297)
                     /locus_tag="IXR05_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260697.1"
                     /translation="MTISVGNKVKYIGTAIPRYTNKLVVVKNILVNGLILEYPKEDRR
                     KVVVEGNGTWNMNSFICGFTEVEVTNDNENRSG"
     gene            complement(9283..9605)
                     /locus_tag="IXR05_002218"
                     /pseudo
     CDS             complement(9283..9605)
                     /locus_tag="IXR05_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9728..10843)
                     /locus_tag="IXR05_002219"
     CDS             complement(9728..10843)
                     /locus_tag="IXR05_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260698.1"
                     /translation="MATKRFTATRKYNELYYQFPKVFITSEKYRSLSDKAKIAYMVFR
                     SRLDLAIQRNQVDSQGFVYFEFTEQELANALNCCRRSVNTIKKELKEYELLEIEDMGF
                     DQQTGKRNKARLYLGELDTTENDVYSLGPVDSTSVDSAQGKEEEESVDNLAIFDDFDE
                     KNPCENSAQLFNNSSNNLDTENLDTKIDTTSPVEMADDWQKEFIAHYSESTFVPKDVL
                     TWIVRSSAEWREAKEQLNMIYDSKRIIEKRQRKYNQTHGLSDGSEYRILGETFAEDLS
                     KTYQRCIQNEKIARHEGKAIQNRKGFYFRALLNFWECCVRELNLDPMATKLSDQAEYS
                     LLQAKRSCSYEDLETQIYGLSQLPKISMHNWLEELDT"
     gene            complement(10849..11247)
                     /locus_tag="IXR05_002220"
     CDS             complement(10849..11247)
                     /locus_tag="IXR05_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260699.1"
                     /translation="MVKNKFRATDVLTQATFHMPKLFFIKSSKYYAMTAQAKYAYSLL
                     NEYLEESLIEKRIDEKKHVYISYTNQELAILLNVSEEEIEEIKNELEDYDLLTIEFGR
                     IYLKELIATMEDVRVYQHQNSFLIYGQDEV"
BASE COUNT         3075 a         2380 c         1772 g         4376 t
ORIGIN      
        1 aaaatattcc taatactata tttaataaac tacgttctag atagatacga gatttcaaat
       61 taaaaaacga aaatgagaga tacaaatata tcaaatattt aaaaagtaac cacattttct
      121 ataccactcc ttatcagaaa cagccttatt ctttagaata agactgtttc tgggttgatt
      181 aatttgtctt ttgttaaact accatctaag gcaagttcta aatgtaaatg tggtcctgta
      241 ctatttcctg ttgaacccac ataaccaata atttgtcctt gttcaactgt ttgtcctacg
      301 ttcacgcaat attcctgttg gtgcgcataa agagccacac ttccgtcttc atgctcaatt
      361 gtgacataat ttcctgacaa agtatgatac gaagcttcta tgaccgttcc tgccttgctc
      421 gcatagattg gttctccttg attggctgcc atgtctaatc ctctatgaaa ttcttctcct
      481 cgccaaccga aggaactaga aattgaataa ttttttagag gtaccatata gccttctttg
      541 cttagttgtg gaccagctac ttctttatca tatttgatta agtcataggt ttcgattaac
      601 ccatttaatt ttttatcgta gctagtgtct gttgcgtatc ttcctgttaa aaatttagtc
      661 gcttcctgat aggtttttgc cttacttttc caaacaccat cataaaaaga ggtatttcca
      721 actaagcctt cttttaacag tttggcatag tcttttaagc tttcttcata gctctcatat
      781 tgccgaaaag ttgcttgggt cgtataaagt gtcccattgc ctaaatcttc ttgtgtcgca
      841 aaagagacgc cctttccgtt atgtgtgcct ttgattccaa atagattgta gtttggtgcc
      901 tgagccaatt gactttgtcc gcttgcggat tctaaaatgg cttgcgcgat cataacagaa
      961 gcgtataaat cattttcttg tccaatttta cgagcagatt caccgatttt acggataaac
     1021 gtttctacag acgcgtcttt ttcaaaatga atagtccctt cgttatcttg tgtgctggaa
     1081 gggactaatt cttgtatcgg tgcgcttggt gcttggtggt agttttttgt ctcttctgaa
     1141 ccgattgatt gtgcctgcgg tacgtcattc ataggtacag tcacactctg ttcaggtgcc
     1201 ttttgtgggc gttccgtttt tgttggcggt tccgcttctg tttcggtact tggtttttga
     1261 ggagtctgtg agctttcatc agaaggttgc tcatttggtt cttctgacgg ttcctcctca
     1321 ggttgttgat tgtcttctgg tttgtctggt tgattcggtg tttctggttg ttcttcagaa
     1381 cctgttggtg gagcgttcat ttctggatta tctggtgtat ctattgtatc ttcagtcggt
     1441 gtttctggtt gattttcttc tccagtggaa tttgttgtcg tttcttcagt gatcgttgca
     1501 gattgcgaat ttgtcagttg attgttgcct tgttcattag ccaaaaccgc tggcgtatac
     1561 ccaaatactt gacctactaa taacaaagca gataaacatt tactcgtttt tttcacaaga
     1621 ttgcctccat tcttcaatca atcatctaga gacagctgat tgctgtctct agtcatactt
     1681 taattgcttt gtttcatttt acgacgaacc agaacagccc ccacaccaac aaaaagaaac
     1741 agtcccaatg caattaacac atcgttcact gtttctcctg tttttggtaa gctttgtttt
     1801 ggtgtgctcg tcggcgtttg tttgacaggg gttgtcggcg tttctttttt aatgcctttt
     1861 gctgtcaatg tttgtttttc attcttcaaa tcaaagtgac gtgcttcttc ctctttatgg
     1921 tctttatcct tatagacaat atgagttgcg accaatttct ccccgtcttt taacgtgcct
     1981 gctttgtagt caaaggatac tttaaactct tcagacgctt tagaaacttt acgtgcagtt
     2041 tctaccgtac caacgactgt atcttttcca tttttatcaa tcttatggaa ttgagtcacc
     2101 cagtatttgg tttcccctac cgtagattct ggaaattctt gcgatacatg atcgatcaac
     2161 tcttggtctt tgtctggatc aaatgtttgg tcgccattca ctgtaataaa gcgtgtttcg
     2221 atttttggtt ctttcgcagt cactgtttga tctttattgg ttaaatcaaa atgacgagcg
     2281 aattcttctt cctcttcttt gtcgttatag acaatgtgcg ttgcgacaat cgtgtcaccg
     2341 tctgaaacca tgtctgcttt gtagttgaac gtcacatcaa atgtttcttt ttcatcggtc
     2401 acttttcgtg tttcttttac cgtatctaat acagtgactt ttccatcggc agtaatttta
     2461 tggaattgcg tcacccaata tttctctgtc ccaaccgcag atttagggaa tacttgggac
     2521 actttatcca ctaattcttg gtcttttttc gggttgaaat cttttccacc tgtcgttgtc
     2581 acaaacaaag tagaaatttc tggttggtct tcttctggaa ccacgatttc ttcgtttttc
     2641 acagtaattg gttgtacttc tccgtctttg accgttacta aaatcgtttc tgtttgtcct
     2701 gacgcttgcc cataatgctc agggaacaca atttccgtaa atttatacgt accgtctggt
     2761 aattttagtt tttctggttc ttcttttgtt tcatacacaa aggacacatt tttattatgt
     2821 gcagtcatac cttcaatcag gaatttcgct cctggtaatt gtagatgatt gattgaatcg
     2881 actttattga agtctacttc acccgttttt aacaagttgt caatcacatc taattcaaac
     2941 gtaagcacag gcgtcgtgtt atcgccatag gccacagaga acgtggtttg ttcttcagaa
     3001 ggttgacggt agttgtctgg cacatttttt tcaatcaatt ggtatttgtt ttgatcgcca
     3061 ttgtagaatt ttttgtttgc cttccagtgt ccgtctttgt cagtttttac tgaatccaag
     3121 acttctcctt ttttcacaag gactgtttct ttatctggcg cagtaatatc tgttttggcg
     3181 ataatatcaa attcgatatt ttctgcagga acggtatcat aaacaggttt gccttgattc
     3241 caggattctt ccgcattata gacttctttg actttctttc cttctggaat gaactgttgt
     3301 aagtcatttt ttgcagttaa cgtcacttct ttgtttggtt caatcgtaat cgtatgagtt
     3361 tgtttgtcta gaatataccc agctggtgct ttgacttctt tgacatccaa tttattttga
     3421 acatattttc cgtctttttc atagaatgca gggatttctt ttaaggcgat ttcccctttg
     3481 gcatccgttg tatattgttt tgtttctccc gtatcatgac gtttgatttc atacgtcaca
     3541 tttggaactt ttttccctgt gacagcgtct agtttggtta gtttgaagtc gccatttttt
     3601 agaactttaa tagttagtcc agctctatta ggatctggca cataaagctt tcctagattt
     3661 tgagcaacag gatctacata ggcaaaactt gaacctaccc ctctagaatt tggatccagt
     3721 gaagaaacag aaattcgtcc gtcatttgag ttttgatttg cttttataaa caaactattt
     3781 cctgattttc ttacttgaac gttagctgtg ttttcaacaa ccgacccatc ccattgagaa
     3841 aacacacctt ttgtatcctt aacttctact tcttccccta ctttaaccgt cactgtttgg
     3901 ctatcaaaag aaggatcttc aagtaaattg tttatttttc tatctacagt ctgtttgaaa
     3961 gcttcataat tagattgtcc aatagttcca taattaacaa atgaaccacc taaaacttcc
     4021 caaatatatg tttgtgctaa tacatagtta tccattgaac cactagaata gtagccaaaa
     4081 taaccaatta aagaaatctt ttttctaata gcacttgtcg taattaaatt ttcgagtggt
     4141 gtcacatcat attgaatacc cgcactcgtg attgcgcctt cttgaatgca aaaaacatct
     4201 tctccgtcaa tttgccagcg aaccatgtaa tcatgagtat acattgttcc ttcaggagta
     4261 attcgagtca tattcacatc tttacgacca ttttcagtca atgttagatt ggtagcacgt
     4321 gtctgtgcat tcttttccaa gattgcttgc cattcttcag attcttgcgc caatcgttct
     4381 tgttcagaaa aagaagtcgc tttttgaata tcttcaatgg ttataaagta tttctcataa
     4441 ccttcaggga cctcttgagt cattacattg ggcggagaaa catcttctgt cgtgtcctgc
     4501 gtagttgtct cttctgttgt ttcacttgtg gtttcagtac tgatcgcttc ttcactactt
     4561 tttgattctt cagtcttcat tacttcttca gtagaatttg attcatttat cgtttctgca
     4621 aatgccgtta cagatcctaa catgggattg agaaatgtaa cgaaaattgc caaccaagtt
     4681 gccattcttt taaacatatt tttttcgttc ctttcatttt atttttcagt cttctaaagt
     4741 aatttcttat ggacttcgac accgaaacat ttttatcctc ctcaaaacaa aaaaagacta
     4801 gaacttataa ttctagtctt catcaaccac ttacttttct tttattttta gtagaaatct
     4861 acagtgtgtt tttgtgaccc gtcactgtaa ataataacat ccaccataaa acctttgttg
     4921 taccactgcg aatttggatc gctaacctct gcattagccc aatcataggc ttcatctaca
     4981 gtgttaaata cctttccact attaccaatc tctccaacta caattgttgg ctcttcaggt
     5041 gtcgttgtgc caccatttcc gccttgatcg cctccaccag gattgcttgg ttcttcaggc
     5101 gttgttgttc ctccacctgt gcttgggtta gaaggagttg tttctcctcc agtatttcca
     5161 ccattacctg gttgtgtagg tgtttgagta gtgccaccat tgttttctgg tgtacttggc
     5221 gttgttgtac caccagttgt tcctgtttga tctccagctg gtgttgttgg tgtcgttgta
     5281 tttggtgtcg tttgtgtatt tgaagtcgtt ccttgtccta ctggttgatt cggatcaact
     5341 ttgtctttct cttgaatcac tgtttgagcc acagtttcac ctgcgctgtt ttgtacactt
     5401 gctacattgc cattaaatac taatttattt cctgcataga ttaaatccac atttgtaatc
     5461 ttattcatgt ccgctaattt ttggacagta atatttgttg cttgactgat tgcgcttagg
     5521 gtatctcccc agacaattgt gtattcattc cctttaattt ctgctttgat ttgttccgcc
     5581 gaacgaggtg tccaaacttt gttttctgct gcttcagcat tcgttcccac agcaagacta
     5641 actcctccga ctacgattcc tagtgccaat actttcaaca ttttcattgt ttttcgcctc
     5701 cgatttgaat aaatttattt acaaaaacat agtaccaaac ttatgtctat cagtcgatat
     5761 attttttgta gattttttta ttttttgata tactaacttt ggtactaaaa taactaaaag
     5821 gaatgtcaca catgcaactt aataatttaa atgaaataca tgattgggct caaaataatt
     5881 tacttaatcg taaacaagct gccaaaatca ctggacaaaa ctatgatgct ttttctagct
     5941 ctttacgtag aaataatatc aaaccatttc tagaaatagg cgacgaacct ggtccttcca
     6001 tcattcgctt atatctaaga gaagatattg aaaaatacgc aaaacagctc gaagaaaaaa
     6061 gacagaaacg tcaatgaggc gttttctgtc ttggatttac aagtaaaaca ataataaaca
     6121 cttttacaac ggaggttcta tgaataagaa atacattgtt tcagttggtt caatcgtact
     6181 gattgtactc gctattattg ctttttctgt atccaacaaa acagaaacac agccacaaaa
     6241 tacggttcaa tcgactacta caagtcaatc tagcgatcat tccgtctatc cttcactaaa
     6301 tagtttaaaa gaaacgcatg gacaagattt aattgatctt ggttcttctc aaattactac
     6361 tgtcttattt gaaaagaaaa atattgcgtt tattactcct aaagaaggaa ctgaccttga
     6421 attttctatc aaagtaacaa ataccaaaga aaatttattc tccattcctg acattcaata
     6481 tacccctaac aagttaaaga ttggggatac gtttggtttg gctaaagtaa atgaacaata
     6541 ctttgcttac tcactgaaat aagtttctaa tagcaagagg aaaaaccctc ttgttatttt
     6601 tatcacataa tcattttata aaaacgcttc gaaaatatca acatttttga agaaactatt
     6661 tttctaattt ctcaatttct tccaagggat tttcgctaat gacccataca ggcacagatt
     6721 gctctcgagg ctccccttct tctaaccacc aacctgcata atgaacttct tcctcctcag
     6781 cattaccatg ataccaacca acaaaggatt catctacaac gaatgaaatt tcttcttctg
     6841 gatcaaataa ttcatttttc catgcttcaa ttgcttgttc tttggtgtac ttttgtttgt
     6901 taaatacacc acaaatttcg tcatctacat aaaaaatttc aaaatcaaaa ttactcgttc
     6961 cttttactgg catcttaact tttcctcctt tgactcactt caatagatat accactcatg
     7021 ttcattccat tgtttactag ttaattggag ttttatctta gggctttgtg cactctttcc
     7081 aaaaacttga gcgtcgtttt tttcttctaa ccaaaaaagg taatttctta cattcggtac
     7141 taaatgtttt tcctgcattt cttcatgaaa aacatataat tctgcttcat ttttcaacca
     7201 attcattatt cattccctca ttcacttctt cataccgcca ttcagatagt gagatttctt
     7261 tttgtttctc cacttgtcct ataaaaatcg ctgtattcaa caagctgatc acacttaata
     7321 ataaagcaat gaaactaatg gttacactta ctctttcaca ttttgtcatt ttgtttcctt
     7381 ctttactcgt ttgttatttc ttgtaatagg tctaataact ccttcaccga aatttgcaaa
     7441 tggttcgcaa aaatttcaat aaaagcactc gcacacatta ccagaccttc aactgatata
     7501 tcactgcgac aataaaattc tggagaaaca ctgatttctg attctttctt acaattgaac
     7561 gaaaaaacta tttttgaatc aaattccggt aattcttcca caactatgtt ttgggattct
     7621 accaagaaag ggagtgcctg ttctaatgct tcttctggtg tttgagcaga tagaataatt
     7681 gcttcttgtt cttttatttc attgttctca aatactttat aacttttttt cattgttagt
     7741 tcctctttca ttcctctctc aattagctaa gccgttactg gtacgccatt ctctaaattt
     7801 agtatcgcta atccttaatg ctcgtcgaat atcaatcatt cgataaccta ttgcacgaag
     7861 ttctttatat cttttagcag ttagcgtctc taacgtcatt tcaggcaatg ggttcgaatc
     7921 aaaaatagaa ttcgaaccga ttatttgggc caattgttgt acttgtaaca gctcttctga
     7981 acttaattca gtgattgctc gattgcctat cattgcatac attttctgtc gaatatactt
     8041 cttttcttgt ttagacaaca tttctatcca ctcctatttt cattatcatt tgttacctcc
     8101 acttcagtaa atccacaaat aaatgaattc atattccaag taccattccc ttcaactaca
     8161 acttttctcc tgtcctcttt cggatattca agaatcagac cgtttaccaa tatgtttttc
     8221 actactacta atttgtttgt ataccgtgga attgctgttc cgatatactt cactttattt
     8281 cctacgctaa ttgtcatttc ctcactccta ttctttttta tccaaaactt tttcctgtcc
     8341 tattcctgcc aacgaatata cttcactgca tgcttaaaca aaacaaaatg ttgccctgtt
     8401 ttatttccgt cttttacttg ttccacatac agttcatatt tggtcacacc ttttaaaacg
     8461 ccagatactt tttttcatcc attgtcacaa ttagtttttt catcaatcga ttgatactgc
     8521 actgctcatt tttcttgttc atatagtatt cctttctttt tcaaaactag cctcttttgt
     8581 ttactagttt tcatcaatca tcaacgattt aacagatttt ttctttcgca gggtttctag
     8641 cgtcagcaac cccaaactct aaaaaagtgc ctttgctccc ttgaaaaacg agcggacgat
     8701 tgtactcgtc atcatatgtt tttcatacta cctgatccac gcaaataacc tttttttgtt
     8761 ctgtgccaca cccatccata cgtatcgctt gagattcacc atactttttt aggtggttta
     8821 tccttcctaa gtccctgtta gacacgctga ttaacttaga aagtcctgtt tgtatccaat
     8881 tttcaaagat ctcccaaaag aaataagtag gtttacgtgt atcgcttctg ttcaaagtac
     8941 ctgtttgtac ttgagtattt ctactcccct cgttcaaggg attccttcca ccagctagct
     9001 tttcctttca tcatcaaatg ttcctgaaaa gcatttacgt ttcgtgtccg tgtgcttact
     9061 tattcttttt tcgatagcga ttatccgctc gctactcgct attttatact ttgtttgtta
     9121 gctcaaataa aaactaacaa acaaaaaagg ctagtttctt tccgttttat ttttttaact
     9181 gtcgataaat agttgttagt ttaattccaa gttctaaaac caatacgccc aacaaaacca
     9241 caggaaaaac aattggggca aacaagtaaa atcggatagt tttcatgtct tccctctttc
     9301 tttttggtgt cgctgtggtc gttcttgccg ttcaatactt cgatacattt tttattcatt
     9361 atttgctcgt tttgttttcc tctggactgc ttttcttgct ttttgaatac tttatacgct
     9421 tttcgtgcct gaattaatag gtcttgtcgg cgtttcattc gtgagaaaac aatatttgaa
     9481 accatcaaat cctggttcga acaaccacga ttcgcaataa ttttcccatc aaaaaaaata
     9541 gttttcactt gagaaaaaaa cagttggaaa tcttgttttg ttgctaattt ttttgtcaaa
     9601 atcactgtgc ttttccctgt tgaatctaca atgattcttc gaacaatccg attcgataac
     9661 ttccaacgtt gccgattaaa caatgttact tcacaacaaa tatgacgtaa gtgattaggg
     9721 gtcattttca tgtgtccaat tcctccaacc aattatgcat cgaaattttg ggcaattgtg
     9781 acagcccata aatctgcgtt tccaggtctt cataactaca agaacgcttg gcttgaagta
     9841 atgaatattc tgcttgatct gatagttttg ttgccattgg atctagattc aattctctta
     9901 cacaacattc ccaaaaattc aatagcgctc taaaataaaa tccttttcga ttctgaattg
     9961 cttttccttc atgacgagca attttttcat tttgaataca ccgttgatac gttttgctta
    10021 aatcttctgc aaatgtttcc cctaaaattc gatactcgct tccatcagat aaaccatgtg
    10081 tttgattata ctttcgttgc cgcttttcta taattcgttt actgtcgtat atcatgttta
    10141 gctgctcttt cgcttcacgc cattcagctg aactgcgaac aatccatgtc aaaacatctt
    10201 tcggaacaaa cgtactttcg ctgtaatgag caataaactc tttttgccaa tcatcagcca
    10261 tttcaacagg actagtcgta tcgatttttg tatctagatt ttctgtatct agattgttag
    10321 aagaattatt aaataattgt gcagaatttt cacatggatt tttttcgtca aaatcatcga
    10381 aaatcgctaa attatcaaca gattcctcct cttcttttcc ttgtgcagaa tctacactgg
    10441 ttgagtcaac aggacctaat gaatacacat cattttctgt cgtatctaat tctcctagat
    10501 acaaccgagc tttgtttctt tttcctgttt gttgatcaaa tcccatatcc tctatttcta
    10561 gtagctcata ttctttcaat tcttttttga ttgtattaac agaacgtctg caacaattca
    10621 atgcattggc taattcttgt tccgtaaatt caaaataaac aaaaccttga ctatctactt
    10681 gatttcgttg aatggctaaa tctaagcgtg accgaaaaac catatacgcg atttttgctt
    10741 tatcagacaa tgagcgatat ttttcacttg taataaatac ctttggaaat tgatagtata
    10801 attcattgta tttacgagtt gcggtaaatc tttttgttgc catcgttatt acacctcatc
    10861 ttgtccatat attaagaaag aattttggtg ttggtagaca cgaacatctt ccattgtagc
    10921 aatcaattct tttagataaa ttcgaccgaa ttcaattgtt agtaagtcgt aatcttctaa
    10981 ttcatttttg atttcttcaa tttcttcttc agacacattg agtaaaatgg ctaattcttg
    11041 attggtataa gaaatataga catgtttctt ttcatcaatc cgtttttcaa ttaaggattc
    11101 ttctaagtac tcattcagta agctataggc gtattttgct tgtgcagtca tcgcataata
    11161 ttttgacgat tttataaaga atagttttgg catatgaaaa gttgcttgtg tcagcacatc
    11221 tgttgcgcga aatttgtttt ttaccatatt ttttcctcct agaaaaacac gcaaaaaaag
    11281 ctctgtataa atcgaattac acagagtttc ttcttgttga tatttaattt ctaaaatacg
    11341 tttcgggtaa aaactaaaca cttactaata tttagattgt agaatcttcg ccttcattta
    11401 ttcattttaa agagaaaaag atcaagtgaa atgtgcccaa aagtttgatt ctattaattt
    11461 ttaaacacca ttcataatat atttcctata atgtaaaaag cgtcgatact tattaaagca
    11521 tcgacgttat ttttatagta aatttatcaa aatttttgcc aacatttttt ccgatttttt
    11581 tccctatttc tatctttcct tat
//
LOCUS       DACGDM010000082        11520 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.087, whole genome shotgun sequence.
ACCESSION   DACGDM010000082 DACGDM010000000
VERSION     DACGDM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.087"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(122..667)
                     /locus_tag="IXR05_002221"
     CDS             complement(122..667)
                     /locus_tag="IXR05_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4260700.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(679..1371)
                     /locus_tag="IXR05_002222"
     CDS             complement(679..1371)
                     /locus_tag="IXR05_002222"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAQ4260701.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYKPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1390..1674)
                     /locus_tag="IXR05_002223"
     CDS             complement(1390..1674)
                     /locus_tag="IXR05_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260702.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1687..2250)
                     /locus_tag="IXR05_002224"
     CDS             complement(1687..2250)
                     /locus_tag="IXR05_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4260703.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2478..3140
                     /locus_tag="IXR05_002225"
     CDS             2478..3140
                     /locus_tag="IXR05_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAQ4260704.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3264..4460
                     /locus_tag="IXR05_002226"
     CDS             3264..4460
                     /locus_tag="IXR05_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAQ4260705.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4561..5937)
                     /locus_tag="IXR05_002227"
     CDS             complement(4561..5937)
                     /locus_tag="IXR05_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4260706.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5974..6840)
                     /locus_tag="IXR05_002228"
     CDS             complement(5974..6840)
                     /locus_tag="IXR05_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAQ4260707.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6929..7954)
                     /locus_tag="IXR05_002229"
     CDS             complement(6929..7954)
                     /locus_tag="IXR05_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4260708.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7972..8646)
                     /locus_tag="IXR05_002230"
     CDS             complement(7972..8646)
                     /locus_tag="IXR05_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260709.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8830..9723)
                     /locus_tag="IXR05_002231"
     CDS             complement(8830..9723)
                     /locus_tag="IXR05_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4260710.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9797..11494)
                     /locus_tag="IXR05_002232"
     CDS             complement(9797..11494)
                     /locus_tag="IXR05_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4260711.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
BASE COUNT         3421 a         2523 c         1974 g         3602 t
ORIGIN      
        1 acgtaaaaag aataagtttt tttaaaataa cgtataaaaa agagcataaa acaaagtcgt
       61 ttgttttatg ctcttctttt attattttgt gctttttatt ttatcaaatc actttgtttt
      121 tttataaaat ttctgcgcct agtgtggact caaaatgtct caatgcccat tcatgtccaa
      181 cgggatcgaa acttgccacg gcatctttga aaatatggag tttgtatcct agattatacg
      241 catcgactgc tgtatgcaac acacagatat ctgtacatac gccggtcaaa taaatatctg
      301 tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc actaaaagcg gaataatgcc
      361 gtttgtctat ccaataaaca ttttcctctt gctcatagtc ttggtataaa ctttttaaag
      421 agccgtacaa ttcccgtcca cccgttccta tcacattatg cggaggaaat aagcggttct
      481 ccggatgaaa ggaatctttt ggatcatgcg catcaatggc aaaaacgaca aaatcctttt
      541 gatcaataaa cttctttgta tgagcagtca gctttttttc aattacttgt cctgctgtcc
      601 cagtagtcag ctttccatcc tctgcaacaa aatcatatgt gtagtcaatc gagatcaatg
      661 cgttcatctt agtcctcctt atacgagatg tttgacaaat tcgatcacca tttctgctga
      721 tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt gtcgccgagt gatctgctgt
      781 gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac tgacgagctg tttgtccaac
      841 agcggctcct tccatttcgc aagctaatgc ttcagggaaa ttcgttaaga tttctttgat
      901 tttatctggc gagtcgacaa atgtatcacc tgtaacgatc aatccttctt ttgcgttcaa
      961 attcgttgct tttgctgctt taaccatttc actgcgcaaa tatgtgcttg cttcataata
     1021 tagaggcatt cctggtaatt gtcctggttt gtagccaaat cctgttgcat ctgcatcaaa
     1081 ataagctact ttgtctgata taacgatgtc acctacttgt aagccttcac cgattccgcc
     1141 agctgaacct gtattgatca ccatgttcac gccgtattgt tggatcaaca gacttgtggt
     1201 aatagatgct aagacttttc ctataccgga acgtacgacg atcacttcgt ggttacctaa
     1261 tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat aatggttcgc ttaggttctc
     1321 tctcaaaatt tttacttctt cttccattgc gccgataata ccgattttca tctttttaat
     1381 tccttctttc tatataaatg cgattgctaa aaaaaccaca cataacatta ggataacaat
     1441 aataagagat ttcatcaaaa aagagttcca tttggtcgtc ttttcccgtt cgctgatcct
     1501 tgttttcgtg attggtttat tctttttgct ttctttacga taaaagctgg caatcttttt
     1561 ttcttcttgc tgataagctg tttctgcttt tcgctgtttt tttaatgact cgcttgcttg
     1621 tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc ggtcctttgg ccataagccg
     1681 atccctctac tttcctttgg tcaatagttc ccagtattga atcgcataaa tcgtctttgc
     1741 atcacaaatc aactgatctt tcatcgcttg ttgcgcctct tcaagagtta gatgatacaa
     1801 ctccagtact tcgtcttcat cttgtgctaa aggattctcg accttctcta ccccttgtgc
     1861 atgataaata tgaaggactt catttgcaaa acctggtgaa agatacatcg aagtaagatg
     1921 gctcagcgac ttcgcacgat agccagtttc ttcttctaat tctctagctg ctgtcatttc
     1981 gggattttgt ccttctcctg gatcgatttt tccagctgga atctccaaaa tcactttttc
     2041 taaaggtttt cgaaattgtt tgacaagaag cagacgatct tgttcgtcaa aagcaatgat
     2101 cccgacacca ccaggatgaa ataccagttc tctcttcgaa gttcctccat ctggcaaacg
     2161 aacttcgtct acagcaacat caataatttt tccgctatag atttctttgc gactgattgt
     2221 tttttcttca aattgctcat tgttcagcat atcttctcct gctttctttg taatcataac
     2281 tgcttttttt tcatttttca atttttctca aaaactcctt attagtttac catagataaa
     2341 ccttagattt tctctaaata tagaaaatcc ttctttagtc cgatactctt tctagtagtc
     2401 cgtatgctaa aataagtatg taatcgaata acgaaaagaa ttcaatactc aacgataaat
     2461 gacatggagg gtttattatg ataaaacgaa attggccgtg gcttctagca ttggtcttgc
     2521 tatttctctt tgtccgaaac aatagttttt cttttgttct aggactttta ttgataggtg
     2581 tagttttagt tttgtgggga ctctttggtt cgcgcaggaa aaagggaaaa caagaagaaa
     2641 ttcctgcact gactgacgaa cttgaaactc actatgaaaa aagcggtatg acagcgaatg
     2701 aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa tgagatcaat caattgcaaa
     2761 tgaatatgca gcagacagcc aaacttaaag caatcgatct ccgccatgat ccagtcaaag
     2821 cagcgaaagc tttattcaaa gaattggtga aagaaccaaa ccgactgcat gaagcaagtc
     2881 agtttcttta tacgcatctg ccgaatctag ttgatttgac aaataagtat aatgagatca
     2941 atgaccatga gatcaaaaac aaacagacct atgaaaaact agaagaaagc gcgcagatca
     3001 tcgaccagct gtcagcttta atcgcacaag attatcaaaa attcgttgct gaggatctag
     3061 atgatatcga cgtagagata tctgttgcga aacagagctt aaagcgtgat aataaatatg
     3121 aaccagaaca aaaggattaa ctcttttgtt cataaaagaa gactcggaac attcagatga
     3181 tgtctggctg tttcgagtac tttttctaaa gtagagacat tcatgtaaga atcgagaaca
     3241 gattcaacaa ggaggaattt tttatggatc ataaaccgac tgaaacaaaa gatgttacac
     3301 cagttaacga tacacttgaa gatttattga acaacccgtt ttcaactcca acagatacgc
     3361 tgaccacttc acaacaagcg gagattgatc agctccaaga gcaacagaca gctgctcgtt
     3421 taattgacaa actaccggcg gaacgccaag aacaagctaa acagctagca gcaaaaatcg
     3481 atgctaatga tgcacagtct gtcatcagct acggatcggc tgcccaagca aaattaagtg
     3541 aattctcaca atcgatgttg aatcatgtgc aagcacaaga tattggtcct gtaggagatt
     3601 ccttaactga actgatgtat cgtctccaag aagccaatcc tgacgaactg cgtgccggag
     3661 aagggaacat cttccagcgt gtcttcggga aggtcaaaca atcgatctat gaagtgacag
     3721 caaaatatca aaagattggt gcacaaattg acaagatttc agtgaaatta gataaagaaa
     3781 aagacggtct gctaaaagat aatctgatgt tagaacagct ttaccagaaa aacaaagact
     3841 actttgatgc actgaatatt tatatcgctg ctggagaatt gaaaatggaa gaacttcaaa
     3901 caacgatcat tccagaagcg atgaaaagag cagaagaaac tggcgatcag atggatgttc
     3961 agattgccaa tgattacacg caattcctag atcgtctgga taaacgtacg catgatcttc
     4021 gcttagctag acagatcacg atccagcaag caccacaaat ccgtttgatc caaaacacaa
     4081 atcaggcctt ggctgaaaag atccaagcat ctatcgctac agccattccg ctgtggaaaa
     4141 accaagtcgt gatcgcattg accttgcttc gtcaaaaaga tgcagtaact gctcaacgcc
     4201 aagtctctga aacaacaaac gacttattga agaaaaattc agaaatgctg aaaatctcag
     4261 ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga tatcgagacc cttcaaacca
     4321 ctcaaaatga tttgatcgaa acaatccaag agacattgcg tatccaaaaa gaaggaaaag
     4381 aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga agaagatctg aaacaaaaac
     4441 tgttggattt aacccaatag atcacctttc gcttgttact aaaacaaacg cccaacaaca
     4501 gtttattaca actgttgatg ggcgtttttc ttatctttct tctaacttct ccattggagt
     4561 ctatttctca ttcatcttgc tgtgtccata gccatagcca aaataaatga tcagtccaat
     4621 aaccattacg ataccgaaca cgatccatgt cacagtttgc agacgaagca tcaatacaat
     4681 acaagtcaag atggagacga ttggcaatag cggaacgaat ggcactttga attctccagc
     4741 ttttggtttg ccaaacattt ttctcaactt cagtaagcct agactaacaa gcatcaaata
     4801 ggcgagcgcc atgatattcg ttagttccgc taatacattc aatgggaaaa atccggcaaa
     4861 gaatacagct gccacaccag cggcataagt cgcttttttc ggtgtacgat gcttttgatc
     4921 gatttctgtc ataaacttag gaagtaagcc atccttgctg acagcaaaca gtaaacgagc
     4981 aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt aaaattgccc ctacagcgat
     5041 caccgcgccc actgttccat gtcctacata cctcattgca aaagccactg ggtcattgac
     5101 tcctagttca gtatacggaa cgattcctgt caagatcagc gtcacgatga tgtaaaggac
     5161 agtagcaatc agtatcgaac caatgattcc tcttggcaca tctttttgcg ggtttttgac
     5221 ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa gcaaaaaaca caagagctgc
     5281 accatctagc acaccggaaa aaccaaaagg catgaatggc tgccagttat caggtttaac
     5341 gaaaaatatt cctacaatga taaacaacgc gatgatacca aatttgacat ataccatggc
     5401 attattcaaa cgtaatgctt tcttggcttc aagcgacacg atgtaagtga cgaatatcac
     5461 tacgagcacc gcaatcaagt caatgtatgt accattttcc ggattgtacc cgccagttaa
     5521 tgcttgtgga agttcggccc ctaaactttt caaaaaacct tgcatatagc cagaccatcc
     5581 ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc aacaaccacc ctgtcagcca
     5641 ggcagcaaat tcaccaaata caacatacag ataggcatat ggcccaccaa tcactggcac
     5701 tcgcgaagca aattctgcga aacttagtcc agacaaaatg acaacgattg cagctaagac
     5761 aaatgaaagt gacagtgctg gaccagcatt ttgattggcc gcaacccctg tcaccacaaa
     5821 tattcccgta ccgatgatcg caccaattcc aagcatgatc aaatcagacg tttttagttc
     5881 ttttttcatc tcactcgtat gattgagatt gatctctttc ttacgaaaca aatccattga
     5941 agttcctccc cattttaggt tggaaaacag cgattaaact gttttcatat accctaaaag
     6001 gataccacct aaaatgacta aaaggcaacc aacaataaca taaatgagct cttttttcgt
     6061 ttttctttcg ccaaggatga aaatcccacc taaagtagag ataatgatcc ccatttgtga
     6121 aagtgagaag ccaacagcta aaccaagtga tttgactgtt agaagcatgc agatgtttcc
     6181 taagccccat aataatccac agatcatgtt tttccacaca aactgatcga ctttaacttt
     6241 acggaaagca aagaagcttg cgcctaagat cattccgata ctttgaggta agataattga
     6301 catcgcatcc aaattcgccc agttgacgat gatggtatat acaccataac caatcgtaga
     6361 gaagatcaat gctctaaaac ccttaccaaa atcaagcatt ttattatctg tatctatttt
     6421 tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt acaagaagag ctaaagcaat
     6481 aataccgtat acataatctt tcgtttgtgt ccattcatgg aagaaaacgg ctcccgcaat
     6541 cgtattcaaa attaattgaa aaccagtaga caatggtagc cctacagaaa cacccatgta
     6601 cttcattcca tggaactgtc cattttgtcc aacactccaa gctaagccgg ataaaaatcc
     6661 gatcaagaaa atccaagggg tgattacagg actaacaacg aaaaagacaa ctaaagaaaa
     6721 cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg gcatcgccac caattttacc
     6781 acttactaaa ccaatactac cccatgccaa catagggact aatgctatta aaatttccat
     6841 aaccaatctc cttttatttc acatgataag aaacttatca gcgaaaacgt taacaacaca
     6901 agcacttttt ttcgtttcta acgattttct aacgtttttc attataaaaa tttaagattg
     6961 ggaaaaataa agtcattgtt gtcccttttc cttcagttga ttcagccgtc aaatggatac
     7021 ctaatttttc ggccagattt tttgctaaat aaagtcctaa tcctgttgaa tgtgttttgc
     7081 taagtcgacc atttctccca gtaaatccct tatcaaagat ccgtttcaag tcttccgctg
     7141 ggataccgat ccctgaatct ttaactgaaa ggctgactcc ttgcgcttcc ttttctatgc
     7201 tcacaatgat gtttccgtga tccggcgtat atttgatggc attactaagc aattggttga
     7261 agataaaagc gatccattta gcatcggtca aaacagtatg atcctcacca acgatctcgt
     7321 agcgaatatt tttttggata aaataatttg cctgactgcg tatcacaggc tgaatgattc
     7381 cttttagtcc atattcttgg atgaggtagt cccgcgagaa actgtcgagt cttgcataat
     7441 acaaaacttg ttctacgtat tcatcgattt ttgataattc attttctagt aatgtatact
     7501 tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa tttagaagcg gaaagtggca
     7561 ctttgatttc atggacccat gagtcaatat aatctttttg gtcttgttga ttactgattg
     7621 ctgattgcat tacttcttgg tgttcacgga tcagctgatt gatatattct tctaccagtt
     7681 tttcttcttc tgtcctccca ccactcaaat aattttgcaa aggggaagtt ttttgtatgt
     7741 cggctaattt tccccaccat cttctcttgc tcaagtaacc acccagcaga taaaaaatca
     7801 gaaagacgcc ctcaatcaaa gctaaataag caattgtgct caaatcaact ttgatgtttg
     7861 gcgccagcca catcacaaag atcgtcaatg caataaaaaa cagccatccc aagatcaatg
     7921 tccactgatc tttcaaatat ttaaaaaaat tcatcttaac cgctcatcct ttcagggaac
     7981 gatatatccc tgtcctactt ttgtttcgat atatccttgg atacctgcct gttcgatttt
     8041 tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca tctacaaatc gttcgtcatc
     8101 ccacagtgct cgcagcaatt tttcccgact taagatcttt ccattgtgct tcatcaaaat
     8161 aaataataga cgatattcat ttttgctcaa atcaatgatc tctccgttga tttccatact
     8221 tccgttgtca acattcaacg taatgccatt gtggctcatc atttcactag ataattctgt
     8281 gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca atcagtacat cgatttggaa
     8341 atgttttgtc acaaaatcat ctgcccccat gttcatagcc atgatcatat ccatattcgt
     8401 attcctgctg gagataaaaa tgatcggtac tttcgatact tcacgtattt tttgacacca
     8461 ataatagcca tccaaaacgg gaagattaat atctagtaat acaagctgtg gttcttctct
     8521 ttcaaagtct gagaacactt gattgaaatc ggtcgttcca aaggtttcaa attgccattt
     8581 ctcaagttcc tccatgatca attgtcgaat gatctcttcg tcttcgacta ccatgatttt
     8641 tgccataaaa aatccctcca tctttcttct tgctactaca atatcaaaga agcccttgtg
     8701 aaacaagttg gcttacctgg aaaatgtcat tttagcaaac gttaaaaaaa actggaaata
     8761 tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat ttattatgtt attcttaata
     8821 attggtctat tatctgttat ttttctttcg ttgtttttgt cttttaaatt ttcgataaca
     8881 ccaataaccg aaaagcgtta gcactagcaa tatacctaga aggagtataa gtaatcgata
     8941 aagatggtat ttttttgtct gttctatctt tgaagagact tcttctgtaa agggaactcg
     9001 tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa ggtgtacaag tgataagtgt
     9061 gactagatcc tgcttttctc taattgctaa tgtatttgtt tttgttggaa ggacaacaat
     9121 tttctcaacg acttcataag cgagcatccg accatacact tcaagataga atcggtcatc
     9181 ttgctccatt tcttcaagat ccgtaaagag ttttttctca gcaataccgc tatgggcggt
     9241 aatcacggaa tgtgtactct ctcctccagt tggaaaagag gtgccttgca ggactgtcgc
     9301 tcctctatct aacaaaagat cattcgtttc atcaaataaa ggcaagctaa cattgatttt
     9361 cggaatatag atggctccga tcatatgttg ttcgtaatat tcttttcctg gattttggac
     9421 atttctaacc gcttgctcaa aaggatcttt gacttgtccc attcctggga ttactgatgt
     9481 atgagcaagc gtctgatttt tcttttcatg cactgctaat tgttgctcat gtttttcttc
     9541 tttatcgcgt tcaagctgct tttgataatt ctcgatcctt ctttgatcca aataattgct
     9601 gagagcatct gctaaaaatg gatatgtaaa aactgcagct ccggcaagaa acatcactgc
     9661 cataaataat tgtaataaaa gactgatttg ggtttgaggt ctattaccta ttttcttttt
     9721 cattttcttc accttcttat ttaaaaaaac tgcagcaacc tttataaaac cgattgctgc
     9781 agcttatttt tgttgcttat acttcagact tcattttaga tttacggtac cagctgtacg
     9841 ctccaatcat caaacttatt ccgattagta agaatgccaa gagcccgttc ccaccagtag
     9901 caggaagtga cccgcgtttc atattcggta ctctttctgg ccctggattt tctactccta
     9961 cgatctgaat ttcttcatta tagcttccat aagagatgat aaattcagta aaggctgcct
    10021 cacctgttgg aagtacataa ccttctggcg ccatggtctc tttcatttga taggttccat
    10081 aatctaaccc ttgaacctca aagtatccat ttccatctgc gacaaattct gttgcttgtc
    10141 cgcttgttgc ccactcaatt ctatctgctc ctgattcata aacagctaaa ggcgactccc
    10201 ctttataaaa tattgcgtat tcagaacggt cttcattcca caattcgaat cttgcatctt
    10261 taagcaattc actgcttgat gcatcatatt tttcaaactt tcttccacct gttgtgactt
    10321 tctctggcgg ctctactcct tcttcataat caaattcatc atttcgtccg atttcaataa
    10381 ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt ggaaaccttc aaattatacg
    10441 tgatcgttaa atctcctcca cgtgcatctg ctaatctacc taaagtatct actttggcta
    10501 ctccattttc ttctgtcaaa atcgtcacga caaacccgtt gcttactact tctactatat
    10561 aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac ttctatttcc tgatcataat
    10621 aagttagacc aactgtaggc gtatctgtga ttttgtaatt tttgataaca gcgcttccgt
    10681 tttcaaggac agaatcgatg aaataaggaa taggtgctgt gatcgtgtaa gaagccgttt
    10741 ttcctctttc tagatcaata taagaaatcg tttcttgttc tccagcttca ttaataatcg
    10801 ttacttgtct aaggtcgctt tcctctacat tcatctgttt atctgcttct ctgatttcgt
    10861 ttttcggata caaatgcaca tctgtattgt atgtgtcttt ccatgtagaa ccatcccaca
    10921 cgccatccac catatcaggc atcatcactg gcatcataac aaccattgga gacgcgattc
    10981 tggaaatatg agctggcgaa taagtttcta agaaaagata gactttatct ctagaagaag
    11041 gtgcttcttc cgtcacttgg acggtagaga ataccgcttc tccagcttca ttcgttgttt
    11101 gtttgtcaat acttgtcagt cgatatttta aaaaccaact ttctgtgtgc cgtttttgaa
    11161 tccattcaat cgcttcggca gaattaagac cgtcttctcg ttccggtgtt aaaggattat
    11221 ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa atcaaaatcg actcctggaa
    11281 tattttcttc accaaaatcc gtagaaacca atccgctatt cggtcgttct tccggaacag
    11341 atgagaaacc ttttttgtgt aatgtaatcg tcacttcact tggtttttgt gcgacttctt
    11401 cggctttgac tagttttccg ttcccgaaaa tccctattcc cgcagtaacg agtaacagta
    11461 cactcattcc cgtgacaatc atttttttat tcattttttt ctccccgttc tttttttatt
//
LOCUS       DACGDM010000083        11197 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.089, whole genome shotgun sequence.
ACCESSION   DACGDM010000083 DACGDM010000000
VERSION     DACGDM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.089"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(272..1120)
                     /locus_tag="IXR05_002233"
     CDS             complement(272..1120)
                     /locus_tag="IXR05_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4260712.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1284..2186
                     /gene="gnd"
                     /locus_tag="IXR05_002234"
     CDS             1284..2186
                     /gene="gnd"
                     /locus_tag="IXR05_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAQ4260713.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2188..3189
                     /locus_tag="IXR05_002235"
     CDS             2188..3189
                     /locus_tag="IXR05_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4260714.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3186..3470
                     /locus_tag="IXR05_002236"
     CDS             3186..3470
                     /locus_tag="IXR05_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4260715.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3503..4300
                     /locus_tag="IXR05_002237"
     CDS             3503..4300
                     /locus_tag="IXR05_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4260716.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4314..5147
                     /locus_tag="IXR05_002238"
     CDS             4314..5147
                     /locus_tag="IXR05_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260717.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5165..6022
                     /locus_tag="IXR05_002239"
     CDS             5165..6022
                     /locus_tag="IXR05_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4260718.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            6044..6553
                     /locus_tag="IXR05_002240"
     CDS             6044..6553
                     /locus_tag="IXR05_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4260719.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6590..6991
                     /locus_tag="IXR05_002241"
     CDS             6590..6991
                     /locus_tag="IXR05_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260720.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7103..7456
                     /locus_tag="IXR05_002242"
     CDS             7103..7456
                     /locus_tag="IXR05_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260721.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7490..7933
                     /locus_tag="IXR05_002243"
     CDS             7490..7933
                     /locus_tag="IXR05_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4260722.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7950..9035
                     /gene="uxuA"
                     /locus_tag="IXR05_002244"
     CDS             7950..9035
                     /gene="uxuA"
                     /locus_tag="IXR05_002244"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4260723.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            9028..9741
                     /locus_tag="IXR05_002245"
     CDS             9028..9741
                     /locus_tag="IXR05_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4260724.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            10493..10693
                     /locus_tag="IXR05_002246"
     CDS             10493..10693
                     /locus_tag="IXR05_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4260725.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3768 a         1746 c         2408 g         3275 t
ORIGIN      
        1 atttttttta attttttaga aaataagaaa caaaaataat aaaaaaaaga aaagataaat
       61 tttttactac tgtatactaa ctttgttatc gcatctaaca agtaactcga ataataccaa
      121 tacaaccttc tccaaagatg cgatgacata cgttctaacc caccgactat tgatgttctg
      181 taccaccctt gcagaaccaa aaaagccact accaaatatt tggtagtggc tttttttgtt
      241 ttatggattt ttcgcttttt ctgttatggt gctattcttt gatttcagaa atagtatgtc
      301 gaactttagc gatagaacga cgtgattctt tttcgttgta aaacatcaaa atcacatata
      361 gagagtccaa aatgcttagt tgagaaatac gggaagctaa agcttcagat cggaattctg
      421 tttcttcaga aatagaaata aaaacgacat cgccaagttt agcaagggaa gaattagctt
      481 ggctagtaat aacgattgtt tttgctccag tttttcttac ggtttcagca atatggattg
      541 tttcttttga ttgccctgtg tgagaaatca aaacagcaca gtctttttcc gtcaataaag
      601 aagcttccat caattgaata tggtaatccg tgctgtgaga agttgcgata ggggaacgca
      661 aaaatttatg ataagcgtca gttgctacaa tctctgaacc gccaacaccg aaaaaataga
      721 cacgtttaga ttcattgata atagtagccg ctttttttag atccttttgt tgtaacaact
      781 tttttgtgtc atttaaagtt gaaatactag actcgaacac cttttgcgcc atagtgagct
      841 cagtatctgt tttctgaata ttttcgtgga tagaaatagc agatagatca ttttcttgga
      901 tcaacatggc cattttaaaa tctttaaatc cattataacc aagttttttt gtaaattgaa
      961 aaaaagtaga gtcagcaatg cccagttcac ttgctaaatt gctaatagga ctatgactta
     1021 ctttgcttgg attttctaaa atataatcgg cgatagcctg ttcttttggg ctgaagtcgt
     1081 tgtacattgt tttgatttgt agtcttatgg agacgctcat gagaattcct cattttcata
     1141 ataagattat cattttttcc gttctcatta atgttaaaga tacaaggaga gtaggaaaaa
     1201 atcaaacaaa aaatattttt gtaaaatcta tttacaaaaa aatttttttg tataatgagg
     1261 gtataagaaa tggaggcgct atcatggaaa ttggtgtaat tggtttggga aaaatgggat
     1321 tgaatttagc tttaaactta aaagagcacc atcacaaagt acaaggactc gacatttcaa
     1381 gtacagctgt tagtcaggca agagaaaatg acattcctgc ttatcaagag atctctgaat
     1441 ttctagctac ttttgagcag aaaaaaatca tctggttaat gcttcctgct ggagagataa
     1501 ccgaaaacat gttaagaaaa ctttttccaa aactcggacc aggagacatt attattgaag
     1561 gcggaaactc ttattataaa gattcaatcc gtcgagcaga agagtttcag aaaaatgaaa
     1621 tcggttactt ggattgtggg acttctggag gaatcgaagg agcacgacat caagcctgct
     1681 taatgattgg aggagataaa gaaacttttc tatccgtgga acaattattc aaagatgtag
     1741 caattgaaag aggatatctg tatgctggtg catccggaag cggacacttc ttgaaaatga
     1801 tccataatgg aatcgaatat ggaatgatgc aagcaatcgg tgaaggattc caacttgtac
     1861 aaaaaagtga gtatgctttt gacttggaac aagtcgcacg tgtttggaat catggttcgg
     1921 tgattcgcgg ctggctgatg gaaatcatgg aagatcagtt aaacgaacat cccaatttaa
     1981 gtaattatcg gggaatcgtt tctgcatcag gtgaagcaaa atggacggtt gaaacagcgc
     2041 tagaaatggc tgttccagtt ccagtaattg caactagttt gttcatgagg aatctttcac
     2101 aggaagaaga tagtttttca gcaaaagtag tttcagcact aagaaatggg tttggcggac
     2161 atgaaatagt tgaaaagggt gagtaaaatg ccagattatc atatagcaat cgttaattcc
     2221 agcagtttcg gaagagtctt tccacaccac ttggaaagat taaagtcagt tggagacgtt
     2281 catttcttta ctgttgatca agagattcca ggaaaagaac tagcggagtt acttaaagga
     2341 ttcaatatca ttattgcaag tgttacgcca ttttttcgac gagatttttt tgaaaacaaa
     2401 gatgaactgc tattgatttc ccgacatggt attggttaca acaatattga tttaaaagca
     2461 gcaaaagaac accagacaat cgtatctatc atacctgctt tagttgaacg aaatgctgta
     2521 gcagaaaata atataactaa tttgttgtcc atgcttcgac gcacgacaca agcacaagca
     2581 agagtcaagg acgatcgatg ggaagatcgg gcggagttcg tcggtaggac gctgtttaac
     2641 aaaacagttg gtgtgattgg tgcaggaaat accggaagcg gagtaatcga aattttgcgt
     2701 aacggttttc gctgtgatgt tctagcttat gatccttaca aatcagattt atacatcgaa
     2761 agctttggtg caaaaaaagt agaacttcaa gaattactgg aacaatcaga tatcatttgt
     2821 ttatgtgcga atttgacaga agagaactat cacatgattt ctgataaaga agtcgatcag
     2881 atgaaagaaa atgtttatct atctaatagt gcaagaggcg ctctagttga tgaagaagcg
     2941 atgattaatg gtctgaaaag cggaaagatc gcaggatatg ccacagatgt tttagaagaa
     3001 gaaccgggac gtcaagatca tccgtattta gcgtttgaac aagtagtgat tacgccacat
     3061 atatcggcct acacaaggga atgtttagaa gcaatgggtg aaaaatgtgt cagagatgtc
     3121 gaacagatca gtcagcacct tcttcctgaa cgttctgtcc agacaaagag caactatata
     3181 aaaggatgat gaagaaaatg gtgaacggtt taaaagtgaa aacaggccct caattttatt
     3241 tatatgaaga aggtggtatt tcaaaagttt ctgatctctt gaaatcatac ggcgcgaaaa
     3301 gagtactggt cacccacgga acggtatcat gggaaaaggc gctacctaaa ttagtatttt
     3361 tgaatgacga aacgattcaa tttttttatc atcgttattc tggagaatgt agttatgctg
     3421 aagccagacg aatagctaca atcatcaaaa aaatgaaatc gatttcgtag ttggcgttgg
     3481 cggaggaaaa ctgaccgatc tagtgggtta tagtgccaat cttgcaagaa tcgatttcgg
     3541 agtcatccct actttagcta gtaattgtgc tccatggaca cctcttgctg tcatgtataa
     3601 ggagaatgga caagcagaag ggaaaacaga acacttttac agacaagctg ctttttttat
     3661 aacagatccc caattagtga ttgattcccc tgttccatat ttcattgccg ggttagcaga
     3721 tacactagca aaatggtatg aatctgagct catcttagaa caagattttt tgcaagatga
     3781 atcatttttg aagctagcac aagatactgc gaagatctgc aaagaagaga ttttgaatca
     3841 ttctgctaaa gcaatccaag atatggcaca aagaaaactg acatcggagt tcaaacagct
     3901 ttcagagatt atctttgctg ttgctggttt agttggagga ttaggagata aatacgcaag
     3961 aaatgtggca gcacatgcta tgcatgacgc tatcagtaaa tatattccgg aaagccatcg
     4021 ttttctacat ggagaaaaag tagcgtatgg gattttctat caactggcac tagaaggtcg
     4081 ctgggaaaaa atagacgagt tatatccttt gtatcgggaa ttagaactgc cggtttctct
     4141 agaacaaatg ggattatttc cgaaagataa acagataata gataaaatgg ctgaatttat
     4201 tgattcgaaa gagaaagtgc atttgattcc tatagaggta acacagaaat cactgataca
     4261 gtcaatgatg gaactggaag gttatatcag aaagatctga aggaggagga cacatggaaa
     4321 cattaagtgt agtacaaagt ttgttgattg ctttatgggt agccgcggtt atgtcccgct
     4381 ggttaggtgg aggagccacg ttgaccttac gtttttctcc tttgatgact ggattagtcg
     4441 tcgggttgat catgggggaa gttgcacaag cgatgattgt tacagccgct ttgcaaatga
     4501 tttatatggg ggttttttct ccaggaggat caatgccagc tgaaccatct attgcagcag
     4561 ctatcgcagt accagtcgca ttattagggg atctgtcgcc agaagcagcg attgccgttg
     4621 cggtgccagt cggattgctc ggaagttact tgtatcagtt tcgttttttc atcaatactt
     4681 ttttaggtaa atatacagac aaagctgtag aagatttgaa tacaaaagct atggcccgat
     4741 caattattct ttatccaacg gttgcctcat ttttattatt cgttccgctt gttttcattg
     4801 ctttatattt aggggcgcca ttgatcgctg atgtaatcaa agctttagag ggaacagtcg
     4861 ttatccacat tcttgaagta gtaggtggag ggttagcggc aatcggtatc gcgacaactg
     4921 tatacgttat cggtcgaaaa gattatctgg tctttttctt ccttgcttat tttatgagtg
     4981 ttgttttgaa atctttagat attacgatgg ttacttatgc catttttggg attattatcg
     5041 ctttgatctt tgtccagtcg caaaaaggga aacaagtaca gcctgccaca agcaataaca
     5101 attcagcatc ttttgatgac gaagatgact atgatgacgg attttaattt aggaggaatg
     5161 ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca cgaaaaaaga
     5221 tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact cttttgaacg
     5281 ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac tttataaaga
     5341 tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca ctcaattaag
     5401 ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcaaa gagcagaaga
     5461 agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca cgaaagcggg
     5521 attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg tccaatatat
     5581 ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg cactttttcc
     5641 ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa gacaagcttt
     5701 cactatgggc cgtaatgcta caggcctaaa gcaaaacact ggtgttcaga cagcgattga
     5761 aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact atgtaaaagt
     5821 agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg aaattcttga
     5881 tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact tgttctatac
     5941 gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat taattgtgct
     6001 agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg tagtcaattt
     6061 agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat ctcaaaaaag
     6121 tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat ttatgagaga
     6181 tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta caccagagaa
     6241 agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt tgatcgcaaa
     6301 aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag aattgaatat
     6361 tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat ctgtttattt
     6421 aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg taaagaatat
     6481 ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat tgaacaagtt
     6541 tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa tgaagaagaa
     6601 cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc gccgtacaaa
     6661 aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta tgagaacaga
     6721 tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt atgttggaga
     6781 tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc atgcattagg
     6841 aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact ctatattatt
     6901 gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata acaaaaatcc
     6961 tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag catttgggag
     7021 ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa cttttattcg
     7081 aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg atccgagtgt
     7141 agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca gcgtgagatc
     7201 gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag atacaccgct
     7261 acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag ttgataagtt
     7321 gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc agttcttcta
     7381 tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca atcagattat
     7441 tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa tgttggaaat
     7501 catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg aagtaattgt
     7561 cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca tccaaacatt
     7621 cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca tgctagtatt
     7681 tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca atgaactgac
     7741 tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa tgttgttaga
     7801 agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac aaattgtcaa
     7861 acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa aattagatga
     7921 ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg tatggtgaaa
     7981 aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat gggataattg
     8041 gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt gaggagttga
     8101 aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta gcgatccacg
     8161 atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat atacgaacaa
     8221 tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa ccaatttttg
     8281 gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct cttttatacg
     8341 atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata cacagccagt
     8401 caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc gctcagctgg
     8461 aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact tattttttag
     8521 aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat ccagatgatc
     8581 cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac ttgaagaaaa
     8641 ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga tctttagggg
     8701 caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc atccattttg
     8761 tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg gcacatccct
     8821 ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa gaagggttcg
     8881 acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct atgcctggat
     8941 atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat gaggcgataa
     9001 gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat ctttgatatg
     9061 gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa atcagcacaa
     9121 aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca aacagaaatg
     9181 gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat caaatggcga
     9241 gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt atatacgaaa
     9301 aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac aatcgtggct
     9361 tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct atatgccttg
     9421 tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc agagatcttt
     9481 ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt tgaagactcg
     9541 attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat caaagatcat
     9601 ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt aagtttatat
     9661 gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg atttttagaa
     9721 agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta tttattgtcc
     9781 tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt atctacctta
     9841 tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta ccagtagatg
     9901 cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta tgcagatttt
     9961 tttaattctt gcactgcttg ttcgatcgta acacctgtcg ctacatgatt ggtattttct
    10021 ttgtcaaaaa cgacaaatag attcaaatct gtatccaagg ttactcgata ttgtatatct
    10081 ttgttataga atgtcatagc cattctcctt tctttaaata cttgctgaaa ggcaacgaac
    10141 gcgttgataa cgaaattcca tttataagta taccaccaat tgaaaggttt tcatagttaa
    10201 gaaattttaa agtcaaaagt tgcagataaa agcaaataaa caagaaaaca aaaagtgaat
    10261 caatcgcggt tattcaactt tttcttcgat tcgaagacaa tagaagacaa tgaattttat
    10321 atttcattgc attatccttg tgttattaga aaaagcatga tatattaaat gagtaatcta
    10381 ttttgaaacg taatttgagc gatatatcta catagataaa actccttttg cctatcaaat
    10441 atttattgca acgaaaaaac gtacattgat acgtatcagg aggaatttat ttatgaataa
    10501 cggtacagta aaatggttca acgcagacaa aggttttggc tttatcactg gtgaagatgg
    10561 aaatgatgta tttgcacatt tttcagctat ccaaggtgac ggcttcaaaa ctttagaaga
    10621 aggccaagca gtgtcttacg atgttgaaga tggtcaacgt ggccctcaag caacaaacat
    10681 tgttaaagct taataaaaat tgacttttaa ccgtcttttc gaaagaaaag acggtttttt
    10741 tgtacgaaaa aattcattgg tcgttgaatg ggctgaatag tagtgtataa aacaattttg
    10801 tggagcgtga agcttttatg gtagaggaaa atacgaataa agtgatgttg ataaaaagat
    10861 tcctatcttg aatatgaatc gagatgtctt gaaaatgaat gagtttgacc aatcattatc
    10921 ctatcgaaat ttacagtttc gttcgattgg tctgtcaatt aatgaaaaag taaaaaagaa
    10981 tatgttctag gaagagggcg gcacatctaa atttttaagt aacggacagt tcaaatatca
    11041 agcattgaaa gaggctatcc tactgtttga aggaatacga atatataaaa acgacaaaga
    11101 ggaaaaagta gttcattaaa tcccttcaag tgatgaaaga atgagatcta ataaaacctg
    11161 atctttcatc tgttttttta ataacgtaat aattttt
//
LOCUS       DACGDM010000084        11145 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.090, whole genome shotgun sequence.
ACCESSION   DACGDM010000084 DACGDM010000000
VERSION     DACGDM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.090"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            107..1366
                     /gene="lysA"
                     /locus_tag="IXR05_002247"
     CDS             107..1366
                     /gene="lysA"
                     /locus_tag="IXR05_002247"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAQ4260726.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1353..2153
                     /gene="dapF"
                     /locus_tag="IXR05_002248"
     CDS             1353..2153
                     /gene="dapF"
                     /locus_tag="IXR05_002248"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAQ4260727.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDTDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2156..3037
                     /locus_tag="IXR05_002249"
     CDS             2156..3037
                     /locus_tag="IXR05_002249"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAQ4260728.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3034..3750
                     /locus_tag="IXR05_002250"
     CDS             3034..3750
                     /locus_tag="IXR05_002250"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAQ4260729.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3756..4451
                     /gene="dapD"
                     /locus_tag="IXR05_002251"
     CDS             3756..4451
                     /gene="dapD"
                     /locus_tag="IXR05_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAQ4260730.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4467..5468
                     /locus_tag="IXR05_002252"
     CDS             4467..5468
                     /locus_tag="IXR05_002252"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAQ4260731.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5465..6826
                     /locus_tag="IXR05_002253"
     CDS             5465..6826
                     /locus_tag="IXR05_002253"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAQ4260732.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6786..7937
                     /locus_tag="IXR05_002254"
     CDS             6786..7937
                     /locus_tag="IXR05_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAQ4260733.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSGAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7912..9081
                     /locus_tag="IXR05_002255"
     CDS             7912..9081
                     /locus_tag="IXR05_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4260734.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9256..10635
                     /locus_tag="IXR05_002256"
     CDS             9256..10635
                     /locus_tag="IXR05_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4260735.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10916..11145
                     /locus_tag="IXR05_002257"
                     /pseudo
     CDS             10916..11145
                     /locus_tag="IXR05_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3710 a         1948 c         2497 g         2990 t
ORIGIN      
        1 tagacaattc agaaaatttt gtttaatatt attccaataa aattcaaatc tttatcaaat
       61 gaaattccaa taaaaacgga aaaaaagtga aaagaggaat gaaaaaatga cagaattgat
      121 aattggcgga gtcacagcaa gcacattggc agaaaagtat aagacacctc tgtatgtgta
      181 tgatgaagaa aagatgagac aaacgatgct gtcattcaag cgaggctttg tatcgaaacg
      241 ttttgataca aaagtgcttt acgcctctaa agcattccaa acgattgaga tgctgcattt
      301 agttcgtgaa tatggattcg ggctagatgt tgtcagtggt ggggaaatct ataccgcttt
      361 gcaagctgat tttcctagag atactatcta cttccatggt aacaacaaga cgccagagga
      421 actgatctat gcacttgaaa atgatttgtt gcatattgtt gccgataatt tgatggaagt
      481 tgaattatta gcagaattaa gccaacgcta tttaaaaaaa atctgtatca tgcttcggtt
      541 gaatgtcgga gtagaagcac atactcatga atatatcgtc actgcgcata ttgattcaaa
      601 attcggcatg agctatgaaa gtaaagagtg ccaacaagcc cttcagttga taaaagaaag
      661 cagctatcta gagttagaag gatttcatgc tcatatcggg tcacaaattt ttgatgttac
      721 tgcttggtta gctgaaatcg acaaattgac gaattactta accgattttg accaacctct
      781 ttccttgaat cttggcggag ggtttgggat tcgttataca caaaatgatc agccgatccc
      841 agtcgaagag gcactaaaaa aactgattga atatacggaa gaagctttgg aaaaacgaaa
      901 actgaccatt cgtcaattac tgatcgaacc gggtagaagt attgttggag aagctggtac
      961 aacactatac acgattggtt tcatcaaaaa gacaccacat aaaaaatatt actttgtaga
     1021 tggcgggatg acagataata tccgtccagc tctgtatcag gcagaatacg attgtgattt
     1081 agcagcaaaa ctgtcggaag aaaaaacaga gaaagtgacg attgcaggaa aaatgtgtga
     1141 atcaggcgat gtggtaatta aagaagctta tttgccgaaa gcagaatcgg gtgatctttt
     1201 agctgtttat tccacgggag cttatggata ctcgatgagc agcaactaca atcgagcgac
     1261 acgaccagca gttgtttttg tcaataatgg ccaatcaaga ctgattgttc gcagacaagc
     1321 attttctgat ctactaaggg gggaagtttc ctatgatcct tcataaatat aatggctgcg
     1381 gaaatgattt tatcttatta gattacgcag aagacacaga ttatagtcaa ttagccgctt
     1441 ctttatgcac aaaagaaaaa tatgatacag acggattgat cgccgtaaaa atcgatccgt
     1501 tggaaatgat ctattacaac aaagatggca gccgcgcgcc gatgtgcgga aatggcattc
     1561 gctgttttgc tcgatacgta aatgatcaga acatgatgaa tgaacaggaa ttcaacgtag
     1621 agacattagc aggcacaaga aaaattacgg tgttggatcc ctcacctttt tattgcagcg
     1681 tagatatggg agtgccagat gattctccgg aaaaaatcaa agctaatcaa acttatccaa
     1741 taaaaaacca ggaaatagag atcaatggtg aaaaagtaac gatcactagt ttatttttag
     1801 gaacgattca tacagttgtt tttgttgaaa atgcgcgtga ggaagtctgg agaaaaagag
     1861 gtgaactgat ctgtcatcat cctttgttca aagaaaaaac caatgtcaac tttgtagaag
     1921 tagtcaatga acaagaattg atcgtccgta cctatgaaag aggagtaggt tggacacttg
     1981 cttgcggtac aggttgctgt gcctcttatg tggttgctaa ggaaactggg aaaatttcag
     2041 cagatcaggt agttgttcac ttggaacaag gagacttgat gatctctggt gaggatgcga
     2101 tacaaatggc tggcccagca gttcatgaat ggacaagaat attggaggaa tgaagatgat
     2161 aaaaggttcg atcgtggcgc tgatcacgcc gatgaatgaa gagggatcag tagattatgc
     2221 tggtttggaa aaattgatcc aattccattt agatgaacaa acagatggat tattagtttt
     2281 aggtacaaca ggagaatctt ctacgctcac acaatctgag gaggagcaga tccttcaact
     2341 gacagtaaag aaagtggctg gccgtgtgcc ggtgattgca ggagctggaa cgaataatac
     2401 gaaagaaacg attgaaaaag cgaagcattt tgcttctttg ggggcagacg cacttttggt
     2461 catcacccct tactacaaca aaacaagtga tgcaggacta gctgctcatt ttacagcaat
     2521 tgcagaagcc tcaccgattc cgcttatttt gtataatgtt ccttctagaa caggcatgtc
     2581 gattccaatc catgtattag taaatttagc agaacatcct aatatcattg gtttgaaaga
     2641 agcctcagga gatatggctt atgtgatgga tgccgctcgg ttgattggag aagaattctt
     2701 cctttacagt ggaaatgatg atttgatcct accagtaatg agtgtaggag gaagcggtgt
     2761 aataagtgta tgggcgaata tccaacctaa aatagtccat gaattagtaa aagatacgca
     2821 ggacggaaga tggcagcaag caaaagaaaa gcaattaaat gcacttgaac tgatccatgc
     2881 cttgttcagt gagaccaatc ctattcctgt caaagcagcc atgtcattat tagacttacc
     2941 ttccggacct ctacgcctgc ctttagtttc tctttcaaaa gagaaaaaga aacaattagc
     3001 tcagcttttg ttaaaagaaa ggacggttga aaaatgaaaa tcggactgat tggcagtgga
     3061 cagatgggaa atagagtcga agaagttgca caagaaagag gagatacggt ccttctttta
     3121 cggacggcac ctaaagaagc aactacgctt gcttttacgg aactgccaga actgcttatt
     3181 gatttttctc atccagataa tttagagaaa atcctttcgt atagcttatc atatcaactt
     3241 ccgttagtca ttggcacgac aggttataca caatcacagt tccaagaaat aaaagaacat
     3301 gccaaacatg tacctgtgat gtatagtgct aatttttcgt tcggcatcat ggtgatgaat
     3361 caactaatca agcaagcagc tgcaatgttg caaggctggc agatcgaact gattgaaaaa
     3421 catcatagtc gtaaaaaaga tgcaccatct ggtactgcaa atatgctgct tcaaacaatc
     3481 caagaagtgc aaaagctgca gcccgtatac aactggcaag ggaaaaaaag agaagaaaac
     3541 caaattggtg tacacagtat tcgtgcaggt tctttacctg gtgaacatga tgtattgttt
     3601 gctgctactg atgaaatatt tacgatcaaa catgaatctt tttctaatcg aatctttgct
     3661 gcaggcgcag tagaagcagc ggactggttg aaagatcagt caccaggtta ttacaaatta
     3721 gaagatttat taatggacaa aggggtgtaa aaaacgtgga agctcaagaa atcatccgct
     3781 acattcaaac ggcatctaaa aagacgcctg tgaaagtcta tctgaatgta accgagccaa
     3841 tcgaatttaa agaaagtaaa gtttttggtg aaggaagcag cttcgttgtt tttggtgact
     3901 atgagacgat tgctccggtt ttagaagctg aatcagaaaa aatcattgaa atcgaaatcg
     3961 aaactgctgc aagatacagc gcagttcctt tgctagatat taaaaaaatt aatgctcgta
     4021 tcgaaccagg tgctattatc agagatcaag tgtcaatcgg caacaatgcc gtgatcatga
     4081 tgggagcgat tatcaatatt ggtgcagtaa tcggtgaaaa cacgatgatt gatatgggtg
     4141 ctgtcttagg tggacgagcg acagtgggca aaaactgcca tattggtgca ggagctgtct
     4201 tagcaggtgt gatcgaacca gcatcggcca aaccggttat cgtagaagac ggcgtactgg
     4261 taggtgcgaa tgcagtgatt gttgaaggtg tccatatcgg aaaagatgca gtcgtggcag
     4321 caggagcagt ggttttagaa gatgtggcag cagaaactgt tgtcggtgga atacctgcac
     4381 gtgtattaaa aataagtgat gatcagacaa aagaaaatac agcattgatt gctgcgttac
     4441 gcgaattata gaggagatgg agaaaaatgc gcgaaataga tacctgtatt gtgggggcaa
     4501 ccggattagt cggccaaacg atgctcaaag tgttagaaga atatgatttt ccagtaggac
     4561 gattgaaatt attagcttca aaacgttcag ccggtaaagt ttgtgtattc aagaaaaaga
     4621 aacacactgt acaggaattg acagaaactt catttgaagg atatgattta gcgctatttt
     4681 ctgcaggtgc ttctgtatcc aaagagtttg cgccaatcgc acgaagtcag ggactatttg
     4741 tcatagataa ttcctcagca tggcgggaag attcggatat tccattaatc gttccagagg
     4801 tcaatctgga agactataca ttgaatcggc tgattgcaaa tccaaattgt tcaaccattc
     4861 aagcggtact tccgcttaaa gctttacaag aagcctttgg tatccagcga gtcaattatt
     4921 cgacctatca agcagtttct ggttccgggc aaaaaggcat tgaagatctt catcgtacgc
     4981 aaaatgacga ggaaccagtt ttgtatcctt ataatattag ccaaacggtg attccggaaa
     5041 tcgatcagcc tttggaaaat gggtatacaa aagaagaaca gaaaatgata aatgagaccc
     5101 gtaagattct gcatcagcct gctttgccag tatcagcaac ctgcgtacgt gtgccaatcg
     5161 aaaatggaca tggagtctct gtggcagttc aactgcaaaa agagtttacg acggaagaaa
     5221 ttagagagtg tctcagccag tttccaggga ttcaattaga agatgatcta gcagcacata
     5281 aatatccgac gagcattctt gctagaggaa cagatatggt ttatgttggg aggatcagaa
     5341 aagacacttc tttagagaac ggattgttgt tctatacgac tgccgataac atacgcaaag
     5401 gagccgctgc gaatgccgta cagattgctg cagctttaat gcagaaaata gcggaggtgg
     5461 caagatgagt aatacgctga aagtagcgaa attcggcgga acatcgatgt ctcatgaaga
     5521 gcaattcaaa aaagtccgta caattgttct ttcagatccc aatcgccaag tgatcgttgt
     5581 ttctgcttta ggcaaacgta cgtcagatga tgacaaagta acagacttac tttatttgat
     5641 ttatgcttac cttcagcatc atgttgattg gacacccctt tggaaaagga tttgtgatcg
     5701 tttcattcaa gtaagagatg ttcttgccct gcagttacct attgaagatg aactagcacg
     5761 catacagaaa caactggaag acgaaaagat aactgaagat tatttagtaa gtagaggtga
     5821 atatctgact gctcaactga tggctgagta tcttggttac cagtttattg acgcaaaaga
     5881 cctgattttc tttgactatg atgggaaaat cgatcaggaa aaaacagcac aggaaatcac
     5941 aaaagcattt aaaagatatc cgaaaatggt tgttccaggg ttttacgggg cgaaccctgc
     6001 aggaaaagaa aaattattgg gccgtggggg aagcgacatt accggcgcga tactggcgaa
     6061 gatgttgcaa gcggaaagtt atgagaattg gacggatgtt tcaggaatca tgatggctga
     6121 tccgcgaatc atcgatcatc ctaaaatcat cgaggaaatc tcttttagag aactgagaga
     6181 gatggcttat atgggggcta acgttcttca tgaagcagct gttttcccag ttcaagaggc
     6241 tgatatcccc atccaaataa aaaataccaa tgatcctttc gctcaaggga caaaaatatc
     6301 gaatcacgaa atagaaaagg aaaatggact gacaggaata gctggacgca aggattttct
     6361 ttccatcact ttattcaaac gtcatatgtc cgatgaaatc gggtttatct ggaaagcaat
     6421 gagcattttt gctaaacatg agatatcaat cgaacatatt ccttcaggga tcgacaatat
     6481 cggagtgatc gtctcagcag aagcgattgc cgataagtta tttctcatca cgaaagaatt
     6541 aaaagaaaca cttggcgtgg aagaaatcgt cgtgatcgaa gacttagctt tgatctctgt
     6601 cgttgggggt ccgcataaag aattgattgg attatctggg aaagtgttat cgatattgaa
     6661 caaattagaa attcgcacat cgatcttatc acaaggagca caggagttga atctgatcat
     6721 cggtgtaccg aataatcaat atgaaacagt agtgaagggt atctatgaag ggatggtgaa
     6781 tacggatgct gaaagaatat cgaatggcac tccatcaaat tcctgaaatc gggtttcatg
     6841 aattcaagac aaaaaaatat ttatatgaac aagtaaaaaa cagcggggcc gttatccatg
     6901 aaatcggcga aacaggacta ctcctttatt ttgataatca gcaagaagaa acgattgctt
     6961 ttcgaacaga tatcgatgca ctgccagtca aagaagaaac gaatctctct tttgcttcta
     7021 agcatgaagg ttatatgcat gcatgtggtc atgacggaca tatggcgatg cttttagggt
     7081 tgactgactt tataactaaa cacattgagg atcttattta taatgtagta ctgatctatc
     7141 agccatcaga agaaatttcc ggtggcgcac aaagcgttat tcagtcagga ttgttggata
     7201 aatatgaagt acaagcaata tttggctttc atctatggcc tggactagct aagggagaag
     7261 ttttctctcg accaggacct ttgatggcac aaagcagtga aacagacatt atcattaaag
     7321 gccagtctgc acatattgct tctagtgaaa aaggaatcga tagtctggag gcagctgtac
     7381 gatttttgaa gaatgtttat gattttgacc ggcaattacc ggcagagtgg aatcatctaa
     7441 tgaaatttgg ccaaatccaa ggtggaacga tccgcaatgt tttagctgga gaagttattg
     7501 tatccggaag tatccgttct tacagttcag atatgcaaaa ttatttgaag aggggattag
     7561 accatttagc agaacagttt cactctacag ctactatttc ttttcgctat aatgacggct
     7621 atccagctgt aatcaaccat agaggcttat atgcagcact gttagattca aacaaactac
     7681 atgaattaga tgctccagtt cttcaagccg aagattttgg catatatacg caacaatatc
     7741 catgtgtatt tttcttttta ggtgtcggtg atacccctgc tttacatgat ccgacgttcg
     7801 attttgatat ggatgtttta gaaaatggtg tagaatggta caaaacgatt ctttttacag
     7861 aaaatcttct tgtaaaaatc gatagcagtt caaaagagga gcgagtaaat aatgatgaat
     7921 ttatccaatc gatttagtcc taggctttct agaatagaag tatcaaaaat acgacaattc
     7981 gatcagcaaa tatcgtcgat accagatgtg atcaaactca ccctgggaga accggatttt
     8041 ccaactcctg aacatgtcaa gcaagcagga atagcagcga ttgaagaaga cttttctcac
     8101 tataccggaa tgagaggatt agaggaactg cgggaagcgg cttgtatatt tcagcaacag
     8161 cgttatggat taacttatga tccgcaaacg gaagttttga cgacagttgg tgcaacggaa
     8221 gcgattgcct ctgcgttgtt atctgttttg gaagaaggag acaaggttct tattccagcg
     8281 cctgcttatt caggatatca gccattagtg gaactagctg gtgctgaatt gatcccgata
     8341 gatacttctg acacagggtt tgtctgtcag ccggaacaat ttgaacgagc atttgaacaa
     8401 tatggatcag ctgtcaaagc agtcatttta aactatccta acaatcctac tgggacgaca
     8461 ttgtctgcaa aacaattgaa agcaatcgct gaggttttaa aaaaatatcc ggtatttgtt
     8521 ataagtgatg aagtatatgc tgaattgact tatagtggaa cgcatatgtc catagctact
     8581 tatcttccag aacaaacaat cgtgataagc gggttatcca agtcacatgc gatgactggt
     8641 tggcgagtgg gctttatttt tgctcaaaaa gcccttattg acgaactaat taaagtccat
     8701 caatatctgg tgactgccgc tacaacgatg tcgcaaaaag ctgcggctga agcgctaata
     8761 aatggggtga aagatagcga gaatatgaaa gagcaatatc aaacacgaag agactatctg
     8821 gtccagcaat tggcgccttt aggatttgaa gtgacccagc caaacggtgc attttacttg
     8881 ttttgcaaac tcccagctgc cattcaaact gactcttggc agttttgtgt agaattagcg
     8941 gaacaggcaa aagttgcgtg tatcccagga attgcatttg gcccagaagg agaaggttat
     9001 atccggattt cttatgctag cagcatggaa aaattacatg aggcctgcaa acggatcaaa
     9061 gactttttaa cagaacagtg attcatagat tttatcaaaa aaacaatcgt taattttgcg
     9121 gtatattctg caaggagacg attgtttttt aaatttagtt caaatgaacg cgtttctttt
     9181 gattcataac taatgtaatg ttaagtttaa attgtttaga atgattttaa aagaatattc
     9241 aaggaggttt catcaatgga aaaaatcaaa gttgtcattg taggtgcatc tcatggaggg
     9301 catcaatcga tcttggaact attgacacga tacggtgaaa atgtagatat cacgctattt
     9361 gaagcaggag actatatttc cttcatgtca tgtggtatgg agctgtattt agaagacaag
     9421 gtaacagatg taaatgatgt acgtaatttc agaccagaaa actttccgca atccaatgtt
     9481 catattttaa ataatcacga agtaaaaacg atcgatgccg ataaaaaaac agtaacggtt
     9541 actagcgcat cagataacga aacaaaagaa tatccttatg acaaattgat tttgagttct
     9601 ggtgtcaaac caaacaatct gccagtacca ggagcagatc tagaaaatgt ctacttgatg
     9661 cgtggataca attgggcaac caaaatcaaa gaaaaattaa atgatccggc tattaaaaaa
     9721 atcgctgtcg taggtgcggg ttacattggg atcgaagcag cagaagcaag ccgaaaagct
     9781 gggaaagaag tcgtattgct tgatgtgatc gatagacctt taggcactta tttagatgct
     9841 gagatgacag atattttaga acaacaccta aatgaaaacg gtattgaagt tttgacaaat
     9901 gcaaaaatcg aagcttttac tggtaacgga aaagttgagg caatcaaaac aagtgaaaaa
     9961 gaaatcccag cagatctagt cattcaagct gccggtgtga aggcaaatac agaatggtta
    10021 aaagggatcg tcgacttaga tgaacgtggc tggatccaaa caaatgaata cttgcaaacg
    10081 aatcttccag atgtgtatgc agtaggagat gctacacttg cttattctat cccagcacgc
    10141 aaaaaaatgc cgatcgcttt agcgactgtt gcacgtagag aagcacgtta tgtagtaaaa
    10201 catctttttg aagaagtacc aaacaaaccg ttcggcggag tcgtaggttc ctctgcatta
    10261 agtgtctttg actatcattt tgcagcaagc ggattgaata gctttacagc agcaaaagca
    10321 ggagtagatg tacgagtgtc ttattatgaa gatacgttac gaccaaaata tgtaccagaa
    10381 gaacaaggaa atccaaaagt gtccatccaa ttattctcgg atccaatgac ccatcaattg
    10441 ctaggaggag cagtattatc tacctatgat gttacaggtc aaggaaatgt attggcacta
    10501 gcgatccaaa acaaactgac tttagaagaa ctagcagaag ctgacttctt cttccagcca
    10561 ggctttgacc gacaatggag catgttgaat ctagccgctc aacaagcgtt aggagaagaa
    10621 ccatttgtag aataagaaaa cgaaatattt gaaaagaggt tgtgaaaaag ctgccttgca
    10681 tcaagtaata agaacagcca agtaaaaaca gcttcttatg tttttaactt ggctggactt
    10741 attaccgcag atgcaagctt ttgaacaccg tttattttca aaaaagggac tgtgacacga
    10801 tttgtgtacc gacccccaaa agttagacca aaaaatctaa cttttggagg tcggtatttt
    10861 ttatggttaa atatactttt gaacttaaat taaagatcgt tcatgattat ttggatggca
    10921 aaggcgattg gaccgtaaaa atccagatca agagattgaa gcggaaatgc ttaaaattcg
    10981 ggagaagcac aaggattatg gctgtttacg gatgaccaat gaactaagaa accgcggttt
    11041 ctctatcaat aaaaagaaag ttcagcgctt gatcaagaag ctaggaataa aagtaacggc
    11101 atacacgcgt aaatcacgtc gctacaattc ttatcgagga aaagt
//
LOCUS       DACGDM010000085        10930 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.091, whole genome shotgun sequence.
ACCESSION   DACGDM010000085 DACGDM010000000
VERSION     DACGDM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.091"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..287)
                     /locus_tag="IXR05_002258"
     CDS             complement(<1..287)
                     /locus_tag="IXR05_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260736.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAE"
     gene            429..1547
                     /locus_tag="IXR05_002259"
     CDS             429..1547
                     /locus_tag="IXR05_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4260737.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            1675..3051
                     /locus_tag="IXR05_002260"
     CDS             1675..3051
                     /locus_tag="IXR05_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4260738.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            3452..5032
                     /locus_tag="IXR05_002261"
     CDS             3452..5032
                     /locus_tag="IXR05_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAQ4260739.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            5230..5453
                     /locus_tag="IXR05_002262"
                     /pseudo
     CDS             5230..5453
                     /locus_tag="IXR05_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
     gene            complement(5658..5978)
                     /locus_tag="IXR05_002263"
     CDS             complement(5658..5978)
                     /locus_tag="IXR05_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4260740.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(6126..8360)
                     /locus_tag="IXR05_002264"
     CDS             complement(6126..8360)
                     /locus_tag="IXR05_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4260741.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            8839..9105
                     /locus_tag="IXR05_002265"
     CDS             8839..9105
                     /locus_tag="IXR05_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAQ4260742.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            9105..10832
                     /gene="ptsP"
                     /locus_tag="IXR05_002266"
     CDS             9105..10832
                     /gene="ptsP"
                     /locus_tag="IXR05_002266"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAQ4260743.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
BASE COUNT         3480 a         1912 c         2215 g         3323 t
ORIGIN      
        1 ttttctgctt cttcaatcaa tatttttcct aacccttggt gtctgtattc agaaagaatc
       61 gccatccgct gtaatttcat ttttccgttt tctaaaggca aaagacgtac agttccttgc
      121 ggttcttttt tatctgagta caggacgaag tggatacaat gggcttcatc tttgtctatt
      181 tctcgagaca aaggcacacc ctgttcgact acaaaaactt gatgcctgat ccgtacagca
      241 tctaagtaaa tattgctcat tgtatctttt gtttgtacaa ctttcatggt ctagccacct
      301 tcctttcgta tagtatactg gaaaataaaa caaataaaaa gtatggcaag ttttcaaaaa
      361 taaaaaaaga ataaaagaat ttttaacgaa tataatatat actagtaaga aagaaaggag
      421 gaaatctatt gtttgaaaaa cttagacagt ctaaactaat gttttggtcg cttgaattat
      481 tgatcatagc tgcattgatc atgatttcat cagaaataaa ctttattttc gaaccgatcg
      541 ggacattttt ttccacgtta tttgcacctg tactgattgc aggctttctt tactatttat
      601 tgaatcctat tgtcaagctg ttgatgaaag caaaaatcaa aagaatatgg gctgtcgcaa
      661 ttgtgctgct ccttttagtt gcagcaatta tttggatttt acttagtgtc atcccaagtc
      721 tagtacagca aatttcctca ttggcatcta atatgcctga tttcatcaaa caggtagaaa
      781 gctggttaaa agaggtagcc gaattgcctt tgttcaagga agtagatatc aataaatatt
      841 ttgagcaatt agacatttct tacgggacaa tcattcagca attccttagt ggagtatcca
      901 atagtttagg ttcgatcgtt ggaacgatcg cttcggcaac cgtagtaatc attacagcac
      961 cattcatctt gttctatatg ttgaaagacg gagaaaaact agtgccaaac atccaacagt
     1021 ttttcccaga aaaaagaaga aaccaaattg tggagttatt ggggcaactg aataaaacat
     1081 tggctaatta cattagcgga caagcaatcg aatgtttatt cgttggtacc ttcacatttt
     1141 taggatatat ggtaattggt gtggattatg ctttcttatt tggggtcatt gcgggattga
     1201 caaacctaat tccatattta ggaccttatc taggactagc acctgcattt ctagtaacag
     1261 tcttcaatga tccggtaaaa gcattacttt gttgtgtggt tgtgctaatc gtccaacagt
     1321 tggatgggaa tatcatttat cctaatgtaa ttgggaaatc actgaaaatc catccattaa
     1381 cgatcattat cgttcttcta gtagctggaa atattgccgg attgcttggt atcttcttag
     1441 gtgttccttt ttacgcaatc tgcaagacga tcatttccta tataatcaaa atcgtcaaag
     1501 aagacaagca aaatgaaaac aagaagaaaa ttgctacgac ctcgtaggta gttttagtac
     1561 acttgttttt attgcaaaga aaattgcttt gtgataccat tttaacgtgg ctatagtgcc
     1621 acgttttttt ctatcgtaaa ctaaaaatta attttataag gagagaatgc gattatgaat
     1681 gctgaccctg agagtcagtc gctgttagcg cagattttat tattgatcgt tttgacattg
     1741 atcaatgctt ttttagcagc ttccgaaatt gctgttgttt cgatcaataa gaatcgaatc
     1801 gagcaaaaag ctgatgaagg agatgtgaaa tctcaaaagc ttttaaaaat attgcagaat
     1861 ccaaataatt tcctatcgac aatccaagta ggaatcactt tggtcaacat tttgtctggt
     1921 gcttcactag ctaatacttt atcggaacgg ttagctccgg tattaggtgg cggcacagcg
     1981 gcaaaaaata ttgcaaatat cattgtgctg gctattttga cctatgtatc gattgttttt
     2041 ggagaattgt accctaaacg tattgcttta aataaatcag aagaagtcgc aaagttcact
     2101 tcagggctga tacgcttgat tggtgtagta gctaagccct tcgtctggct gctttctgct
     2161 tccacaagtt tattggcgcg tatcacgccg atgacttttg atgatgaaga ttcaaaaatg
     2221 accagagatg aaatgcgtta tatgcttgaa aacgaaggcg tattgaataa tgaagaatta
     2281 gaaatgctcc aaggggtttt ttctcttgat acgaaagttg cccgagaagt catggtccca
     2341 cgaacggatg catttatgat tgatatcaac gacactgtgg aagaaaatgt gaatgaagtt
     2401 ttatccgaaa actattcaag aatccctgtt tataacgaag acaaagataa agtagtcgga
     2461 atccttcata caaagaattt actaaaagct gcccataaat tcggctttga taatttagat
     2521 atcaagaaaa tcatgcagga gcctttattc gttcctgaaa cggtctttat tgatgatctg
     2581 ttatatgaaa tgaaaaagac gcagaatcag atggctattt tattagatga atatggcggc
     2641 gtcgttgggt tagcaacact agaagacctt ttagaagaaa tcgtcggaga aatcgatgat
     2701 gaatcagatg aagttgagaa tctttatgaa aaaatcgatg aacacgaata tatcatccaa
     2761 ggacgtatgc tgattgatga gttcaatgaa gcttttgaca gtgatctgca tatgagtgat
     2821 gtagatacga tggctggtta tttgattaca gcattaggca tgattccgga tgaaggcgaa
     2881 aagttatcgt ttgatgtcga taatattacg ctggtttctg aagaaatgga aggttctcga
     2941 atccttaaaa tccgtgtcat ttttcatgat ccggaagaaa cagaagcgga acctgaagaa
     3001 gaacgaagat acttcagaaa agaattcgaa gatgacgagc caagaagata attggaaact
     3061 tggttatgaa agacgtgttg cttgaataaa caagcaacac gtcttttctt ttagtcagct
     3121 gacaaaaaaa tatttgactc ttatggtttg gtggcttttt cattcgctga atccatgcta
     3181 tactgattca gttgtagtag ttgacaaagg ttgtgaaaaa gctatcctgc attaagtaat
     3241 aagagcagcc aagcaaaaac agcttttcgt atttttggct tgggtgggct tattgctgat
     3301 aggctgtctc tagaacgccg tttactcgga aaaagagact gctacacggc ttttgtcaca
     3361 gccctatatg aaattgtctt tctttaagag atcggacaat ctgtgcctag agaaaatata
     3421 aataattgaa tggaagaaat ggagttaggt tatgaataat ccaaaattaa agcaacaagt
     3481 ggacaatcgc agaacttttg cgatcatttc ccatccggat gctgggaaaa caacgattac
     3541 agaacaatta ctattgtttg gtggggctat ccgtcaagcc gggaccgtaa aaggcaaaaa
     3601 aacaggtaat tttgccaaat cagactggat ggaaatcgag aaacaacgtg ggatttctgt
     3661 tactagttct gttatgcagt ttgattatca agggaaacga gtaaatatct tggatacacc
     3721 aggacatgaa gatttttctg aagatactta tcgtactttg atggccgtgg atagtgcggt
     3781 catggtaatc gatagtgcaa aagggatcga agcacagaca aagaaattat tccaagttgt
     3841 aaaaaaacgt ggcatcccga tatttacttt tatcaacaaa ctagatcgtg atggtcgtga
     3901 accattggaa ttgttagaag aattagaaga gctattagat atcgaatctt atccgatgaa
     3961 ttggccaatc ggtatgggta aagggctaga aggtctttat gatatctacc ataatcgtgt
     4021 agagttttat cgtccggaaa attatcagga tgaacgatta gtagaattgg atgaagatgg
     4081 actgcttccc gaaaatcatc ctctaactga aaattcctta tatgaacaag tcttagaaga
     4141 agtagaacta atcaaagagg ctggagatgc atttaatcaa gaaaaaattg ctcgtggcga
     4201 tcagacacca gtattttttg gttctgcatt gactaacttc ggtgtacaga cttttttaga
     4261 gactttcgtt gaattggcac cagctcctta tggacacaaa acacaagatg atcagatggt
     4321 aagtccttat gaggaagaat tttcaggttt cgtattcaag atccaagcaa atatgaatcc
     4381 agcccatcgt gaccgaatcg cttttgtccg aatctgttct ggaacattcg aacgaggaat
     4441 ggatgtctgg ttggaacgta caaataaaaa actgaaatta agcaatgtca cacaatttat
     4501 ggcagattcg agagaaaacg tcgaaaaagc agtagcaggc gatatcatcg gtgtatatga
     4561 tacaggcaat tatcagattg gggatacatt gttcgaagga aaactaaaag ttgcttatga
     4621 agaactccct tcatttactc cagagctgtt tatgaaagtg actgcaaaaa atgtcatgaa
     4681 acaaaaatcc ttccacaaag gaatctatca attagttcaa gaaggagcga ttcagcttta
     4741 taaaacatat ctaacggaag aatatatcat tggagctgtt ggtcagctac aattcgaagt
     4801 attccaatat cgtatgttaa atgagtataa cgccgaagta atcatgtctc caatgggaca
     4861 caaaatcgct cgctggatcg atccagaaga tttggatgag aagatgagtt caagtcgcaa
     4921 tatcttggct cgtgaccgtt tcgaccaacc gttgttctta ttcgagaacc aatttgcaga
     4981 acgctggttt gcggataaat atcccaatgt aaaattaaaa agtttgatgt aaagaagtct
     5041 tgacacaagc tgccctgcat caagtaataa gaatagccaa acaaaaacag cctctcatat
     5101 tttgtttaga gccgtgacgg attttccgtg acggctcttt ttactatatt aaaatcatag
     5161 aaatgtctaa tcaaaaaaat ataaaaatta ttttgcgtac atatgattaa agaaaggaga
     5221 gtgtgacaca tggaaacaga atggcaaaga cgtgaaagaa aaaaacagaa aaagaagaga
     5281 tgttacgatt atgtcgatta ttagatgtaa aagactggga caaaaacgag caaattgcac
     5341 aaaaagtacg atcaatcatc cataaagagg aaaaagttaa aaataaagac acgcgtagaa
     5401 ctgaaaatga aaagagaaaa gtacaaaaga aaagagaaaa atcaaaaagc tagaaagaaa
     5461 aagaggctga gacagaagcg tttaactcca agaaataagc tggaattcac aaaaatttga
     5521 aaagcaattt tcgtgaattt cagcttattt ccgaaggagt tgcttctgct ttcgccgttt
     5581 atacgtgttt agagcgtgag acaaaagtgt tctttacttt tgtcccacgc tctttaatta
     5641 ttatgttcaa aatttgttta cacggctaat gtagcgccta attcatgttt tggaatcgag
     5701 atttcaacaa ggcctgccaa ttcgattact ttgatttcat cctcgtggta aacggcgtct
     5761 ttgattttat ctaagaaata atttttagca tcttcgattt ctttcggctg gattttacgt
     5821 ttgtcattga tcagcagaat ttcattatgt tcaggggctt cagtgtagac aatagtggta
     5881 tttccggctg tgtagacctt gactagatgg gcatcagtgt tttcaagctg gtttaataca
     5941 agacgggaat ggctgtttgt tacatttacc aatttcatgg cgctcacctc ttttatgtat
     6001 ttttaattgc ttgtttctct tattataatt tcttttttat aaaatgaaca gtattttgac
     6061 ttttctgaaa aaagaatgag acggcatttc tcaaagaaat accgtctcac gctataaaac
     6121 tggatttatt cagccgtttc ttcggctgat tctttagcca aacgttctgg tttagaagta
     6181 acgatgattt ttccatcttt atccagtttt gctttcaact catggataga agggtgatca
     6241 agataaaatt cagcgatacc atcttcgatt tgttcttgga tcgtgcgtcg aagaggacga
     6301 gcacccatag atggatcata gcctaagtca actaattttt ctttgacatt cgtaggaact
     6361 tcgatgtgaa gttgctgtgc tgccagcatt tggttgacat cgtctagcat tagtgtgacg
     6421 attgtcatca agttttcttt tgataatgca ctgaattcga tgatcccgtc aaaacggttc
     6481 agaaattctg gtgtaaagta gttgtttaat tggttcaata cagaacgagt aacaccttcg
     6541 cgtgccgcac caaaaccaac gtttgcttct actttaccag ttccggcatt acttgtcata
     6601 atgatgatcg tatctttaaa gctgaccgtt cttccttgtg catctgtcaa tcgaccatca
     6661 tctaagattt gcaagaacat atgcaaaaca tctggatgag ctttttctac ttcatctaac
     6721 aagacaagac tgtaaggatt tctccgtact ttttctgtta attgaccagc ttcttcgtat
     6781 ccgacataac ctggaggaga accaatcaat ttagagacac tatgtttttc catatattca
     6841 gacatatcga aacgaatcat tgaatcttgt gaaccgaata gttcgtaggc aagttgtttc
     6901 gcaagctctg ttttacctac accagttggt ccaacaaata agaaggagcc gattggacga
     6961 ttctgtttgt ttaatccaac acggtttcgg cgaatcgctt tcgctactcg atctacagcg
     7021 ttatcttgtc cgatgacatg agctttcaag tcatctgcta agtttttcag ttgtgtctgt
     7081 tctttttctt ttaattcacc cactggaata cctgtccgtt gttcaacgat tttttccata
     7141 tctttttcgg taatcacagg tgtttcctct tcagtgagct gacgttcttt cattttttga
     7201 agtttattga tctgatcgcg ataataagct gctttttcga aatcttcttc tcgagaagct
     7261 aaaacttttt gttcttctgc ttcttgcagt tttttctcga ttgttttagg atcaacgatt
     7321 tggatcgtca agtttttctt agaacctgtt tcatctagca aatcgatggc tttatccggc
     7381 aagaagcgat cttggacgta acgattggat aaagttgcgg ctgcttcgat ggcctcatca
     7441 gtatatttta catgatgata gtcttcataa cgtttttgca aacctttcaa aatactgatc
     7501 gtttcttcga cagttggttc atctacccgt acaggttgca tacgacgttc taaagcagcg
     7561 tctttttcga tgatgcggta ctcatttaag gtagtagcac caaccatttg caattctcct
     7621 cgagctaaag ctggttttaa aatattacca gcatccatat ttccatcacc agcagaacca
     7681 gcaccgacga tttcgtgaac ttcatctatg aataggatca cattttctgc ttgacggatc
     7741 tcttcaatca atttttgcat acgttcttca aattgtcctc gtataccagt accttggact
     7801 aaagatacga catctaaacg aatgacttct ttgtccatta atttttgcgg tacatcacca
     7861 tctacgattt tttgtgctaa accttcaaca actgctgttt taccaacacc tggttctcca
     7921 atcaagacag gattgttctt ggttcggcga tttaaaattt caatgactcg tttgatttcg
     7981 tcatcgcgtc cgatcacagg atcgatatca ccttgtcgtg cttgttctgt gatattgatt
     8041 ccgtattctc ccaataaacc ttctgtattg ccttgaggtg gctgaccacc attgaagttg
     8101 ttgtttccgc caaattgtgt tggtggtgtt tgctcataat ttccttgctg ttgcatttgg
     8161 cgagacatgg aacggaaaag atcgtccaaa ctgccaaatc caaatggatc attttgggcc
     8221 atattagtca gacctccatt ttgttgattt ttgatttttt gataacagct ctgacagtaa
     8281 tcgagttgtg tccgctgacc attgacagtg gcatacaagt gaatcgttgc ctcattcttg
     8341 ccgcagtttt gacaaagcat gaatcattca cgtcctttca caaaaatggg tacatccata
     8401 ttttacatct cgtttttcat gaggtaaaag aataacccct agttttttaa gagatttatg
     8461 aggtagaaaa ggtgaaatct ctattgacca ttcctgacct ttgactctta ttatactaaa
     8521 aataaaaagg gaagcaagta attcgtttca tatgaaaaca aagagggtca aaggaaagaa
     8581 tgataaacgt caggagaaga gaaagcgaca agaaaaagga aataaacacg tttgttataa
     8641 aatgtgaaga aaaggatgaa aaagaatccg gaataatttg aatactttta tctgaaattg
     8701 aatgaaaact gttgtatcta acgaaaaaaa atgttaatct ttacagatga aagggtggca
     8761 tttgttagga ttctctgaat tactaaaaaa gaaaaccctc acataaaaac aacactcact
     8821 taaaggagac cgattaatat ggaaaagaaa gaatttcacg tagtagcaga aactgggatc
     8881 cacgctcgtc cagctacact attagtacaa acagcaagca aatttaactc tgatgtaaac
     8941 ttagagtata aaggtaaatc agtaaacttg aaatcaatca tgggcgttat gtctttaggt
     9001 gtaggtcaag gttctgatgt tactattact gcagaaggtg ctgacgaagc tgatgcaatg
     9061 gcagcaatcg ttgaaacaat gaagaaagaa ggcttatctg aataatggtt gaaatgctaa
     9121 aagggattgc cgctagtgac ggtgtagccg ttgcaaaagc ttacctgcta gttcaaccgg
     9181 atttaacatt cagtaaggca acagtagaag atactgcggc tgaagaagct cgtttggatg
     9241 ctgcattagc taaatctact gaagaattgc agcaaattcg tgaaaaagca gcgcaaagct
     9301 taggtgaagc agaagcgcaa gtatttgatg cccatttgat ggttctttca gatccagaaa
     9361 tggtaggtca aatcaagcaa aatattaaag acaacagcgt aaatgctgaa tcagcgctaa
     9421 aagaagtaac ggatatgtat atcggtatgt tcgaagcaat ggaagataat gcttatatgc
     9481 aagagcgtgc tgcagatatt cgtgacgttg ctaaacgtat tttagcgcac ttattaggcg
     9541 ttactttacc aaatccatca atgatcaacg aagaagtggt cgttgttgca catgacttga
     9601 ctccaagtga tacagcacaa ttagatcgca attttgtaaa agcgtttgta acagacattg
     9661 gtggacgtac ttcacattct gctatcatgg cacgttcttt agaaattcca gcaatcgttg
     9721 ggacaaaaga aattactgct aaagtcaaag aaggcgatat tttggctgtc aacgggatcg
     9781 aaggcgatgt aatcatcgat cctacagatg aacaaaaagc tgaatttgaa aaagcaggtg
     9841 cagattacgc agcacaaaaa gcagaatggg aaaaattaaa aaatgcagaa actgtcacag
     9901 ctgacggcaa gcattttgaa ttagctgcaa acatcggaac accaaaagat ctagttggtg
     9961 tccataataa tggtggagaa gcagttggtc tgtaccgtac tgaattcctg tatatggatt
    10021 ctccagactt cccaacagaa gatgaccaat atgaagctta caaagctgta ttagaaggta
    10081 tggaaggaaa acctgtagtt gttcgtacaa tggacatcgg tggagataaa gaactaccat
    10141 atctgcaatt acctcatgaa atgaatccat tcttaggata tcgtgcattg cgtatcagtt
    10201 tatctgaaca aggcgacgaa atgttccgta cacaaatgcg tgcattgctt cgtgcatctg
    10261 ttcatggtaa tttacgtatc atgttcccta tggtagctac actcaaagaa ttccgcgcag
    10321 caaaagcgat ctttgaagaa gaaaaacaaa aattgataag tgaaggcaag gaagtatctg
    10381 atacgatcca agtcggcatc atgatcgaga ttccagcagc agcagtctta gcagacaagt
    10441 ttgcaaaaga agtagatttc ttctctgtag gtacgaacga tttgattcaa tacacaatgg
    10501 cagcagaccg tatgaacgaa cgcgtttctt acttgtacca accatataac ccatcaattt
    10561 tacgtttgat caaaaatgta attgatgcag cacacgctga aggaaaatgg gcaggtatgt
    10621 gtggagaaat ggctggagat caaacagctg ttccattgct agtaggtatg ggtctagatg
    10681 agttctcaat gagtgcgaca tctattctta aaacgcgtag tttaatgaaa cgcttggaca
    10741 cagcgaaaat ggctgaactt gctgatcgtg cattgaaaga atgcgatatg atggaagaag
    10801 tcgttgaact tgttcatgaa tatgtaaaat aaacaacgta tcaaaagctg gtgtggcttg
    10861 taaaagagct acgccagttt ttttgttctt ttttaagaaa acgtttttgt cagtaagaat
    10921 agacaaaaat
//
LOCUS       DACGDM010000086        10817 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.092, whole genome shotgun sequence.
ACCESSION   DACGDM010000086 DACGDM010000000
VERSION     DACGDM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.092"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(25..144)
                     /locus_tag="IXR05_002267"
     CDS             complement(25..144)
                     /locus_tag="IXR05_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAQ4260744.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
     gene            complement(159..1343)
                     /locus_tag="IXR05_002268"
     CDS             complement(159..1343)
                     /locus_tag="IXR05_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4260745.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(1599..1853)
                     /locus_tag="IXR05_002269"
     CDS             complement(1599..1853)
                     /locus_tag="IXR05_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260746.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            complement(1878..3020)
                     /locus_tag="IXR05_002270"
     CDS             complement(1878..3020)
                     /locus_tag="IXR05_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAQ4260747.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            complement(3080..4432)
                     /locus_tag="IXR05_002271"
     CDS             complement(3080..4432)
                     /locus_tag="IXR05_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAQ4260748.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            complement(4503..4847)
                     /locus_tag="IXR05_002272"
     CDS             complement(4503..4847)
                     /locus_tag="IXR05_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAQ4260749.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            complement(4857..5231)
                     /locus_tag="IXR05_002273"
     CDS             complement(4857..5231)
                     /locus_tag="IXR05_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4260750.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            complement(5244..5558)
                     /locus_tag="IXR05_002274"
     CDS             complement(5244..5558)
                     /locus_tag="IXR05_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4260751.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(5672..8897)
                     /gene="fss3"
                     /locus_tag="IXR05_002275"
                     /pseudo
     CDS             complement(5672..8897)
                     /gene="fss3"
                     /locus_tag="IXR05_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
     gene            complement(8976..9638)
                     /locus_tag="IXR05_002276"
     CDS             complement(8976..9638)
                     /locus_tag="IXR05_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260752.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            10255..10485
                     /locus_tag="IXR05_002277"
     CDS             10255..10485
                     /locus_tag="IXR05_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260753.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            10491..10790
                     /locus_tag="IXR05_002278"
     CDS             10491..10790
                     /locus_tag="IXR05_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260754.1"
                     /translation="MLFNETQLWFKFDPTNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT         3000 a         2387 c         1833 g         3597 t
ORIGIN      
        1 aaattttgac cgaaattcat ttcatcactt tcctttcttt tccattgctc ggtccgccgc
       61 tgcacttgca tgcatcaagc acatcacagt aacaccaagc atactgccac caaacaccaa
      121 taaaatatct ttcacaattt ccatcacgat tcctcttttc atataatcaa attttcaatt
      181 gccatacttt gttgctccaa aatctttttg tgccggtctg atagtcgagt attatttacc
      241 atatcctgaa tgtacgttgt ctgattcaac cgatccaact ccttggccat cttccacgta
      301 ggggcgactt gtcgtccaag ccagttcaac gttcgttcaa tggtataagg cttcggttca
      361 gaagttaatt gaatttcctt ctgattccgt ccaatgaagc gcccccattg ttcattcaag
      421 ggccagttag ttcgcctttt gccttccacc ttatccgcaa atcgcaagta ccggttaata
      481 atggaaaatg tggtactttc aatactgcga ccttttaaca aatcttgaat tgcatgataa
      541 gctcgatcat ttttcagtcg gatttcaaaa cgatttttcg tttcggtctg gtctaaagga
      601 atccctaact tgatatattg ctcatagtct ttttcgtaca aacagaaata gacctcactc
      661 ttaagactgc caatatacaa agtattgccc ataccatctt tatcatcagg tttcaacagt
      721 tccccggaac gatagctttt gaaggtacga aacaaggaga tacattcttc cttctgacat
      781 tttttcgtta aatcaggaat atctaacagg ccaactcgat cattgattgc caggtctaag
      841 cgtttcatca cgccaccggc ttttagacaa tcttcgaaaa agtcatacca gctacgcttt
      901 tgggcgagta aaaaagtttc aaactgccga caaccacgac cctttaattc taaaaggacg
      961 cctttatctt cttcatgtga caacatcacc acaatatctc ccataacata ttgttcttga
     1021 taggagtaaa aggcgtaatc ttcgtggagc atataatcaa atttcaaatg gagaatctct
     1081 tgaatgattt tcctcgcatc cgttgtggga aagcgaatcc ttacatagtc aaacagtaac
     1141 gttaaaggta actcgggatt gaaactttcc agttggtcaa aaattttcct catggttttt
     1201 gtcgatgcgg ttacgccacc attttctatc tgatttaagt acgggcgact aagtccacaa
     1261 gtcgtagcta atttattttg tgaaacgcca tattcattac gccggtcttt taatagccga
     1321 taatctaaat tcctttgtgc caagttctca cctccaaatt taaggtgtta actttttcaa
     1381 atcagttaac atctacacaa attgcttatt atccttgata ggacagccat tccttatcgt
     1441 tgcttgctta ttttttgtgt ttttgtaccc ccctgttaga tacggggggt gagacatcat
     1501 ggccggctaa cgccgtccat aaacaggcac agcaccacgg aggatttctg cttcgcaaat
     1561 cccccgcggt cagtgcctat cagtggttta tttggccgtt actccgcggt aataccctca
     1621 atttccaact ctgcttttat ctcaaacaag tattggcgga tatcaggttc tttagcaaag
     1681 tccgcaattc gttccaattc actgatgact tgattcagct ccattcgagc atccgtttcc
     1741 tcatcaatta catacggatc atcagggact ttcaccccgt ttttgcgaat atcaaaattg
     1801 agccggtaca gttcttcttc caattccgga tctgactgaa tcttgccaat cacccagtag
     1861 attccccaat caactcatca taaatcatct gtttttacct cctttaatct tctagcaata
     1921 tcaaaaatga ccggaactgt tacagaattt ccagcctgct tatacaactg actatctgaa
     1981 ttgacttgag aagctcgatc aaaagcccag tccggaaagc cctgaagccg ccagcactcc
     2041 ctaggtgtta actttcgaat ttgatactga tccgtgacga ctgcttgttg gtctcctgtt
     2101 aataaggtat gcacactttg ttttcccaga cggcctcgac gacttgtgga attaggaaaa
     2161 gccaggttca cactgttccc tggcttcacc tcttgatatt ctgtttcgtt tttccgaagc
     2221 atgatcttcg ttccgccttg tttcgttgac aaagtaggcg ctgttccagt tatctcataa
     2281 acccgattgc cttgttcaaa atttcccagt aacatacccg ctacagaaat tccatcatct
     2341 accggcaatg cgattttgat tccttcatca ccggtcaagg taggcgctac gtcatctgac
     2401 ccatagactt gtccccccat tcctcgattg gaagggttga tatttaataa gtttctgatg
     2461 ttttgatcag atgttggaga cgatccaatg ataggaaata cttgttcggt acatgcgtct
     2521 cgagaatgtc cgataaggaa gatccgctca cggttttggg gaacgtaggc ctttgagtta
     2581 agcacttgcc attccacatc ataccccaat ccatccagcg ttcggaggat cgtctcgaac
     2641 gtagcccctc cttcgtgatt gagtaatccc cggacgttct caaggaataa aaacttaggt
     2701 tggagaatag cggcgaaccg agcgatttca aagaataaag tacctcgagt atcggaaaat
     2761 ccttgccgct ttcccgcaat tgaaaaagct tggcacggaa atccaccgca aaggatatcc
     2821 actggtccga gagattgaat aaactcgtct gatacacttg tgatgtcatg catttccacc
     2881 tccttacttg tatcatggat tgccttataa ctctggcgag caaaatcatc aatttcacaa
     2941 aagccgatac actggtgacc cgcttgttcc atacctaagc aaaagccacc aatcccagcg
     3001 aataaatcta aaaatgtcat aaatcacctc gtaaaaaaag cccaggattc ttgacactcc
     3061 taggctacat actattattt tatccttccg tattaacgtt taatccacca atgtcgctaa
     3121 tttcccttaa gaaatcatat ccttttggta caagtggcgt ataaaactca ctaatcacac
     3181 tccctcccgt atctacatag cctcgacctt tgatacgctt cataaagaat tttttatcaa
     3241 cctcgccaaa catcatggaa tatcccagtt cactcatacg acccaaagcc acccggaaat
     3301 taaattgatc gcgaatcccg tctcctaaat atttcgcatc cggtctttga caagctagaa
     3361 tcagaaagaa accagattga cgacctaaca tcacgatttg tttgagctta ttcaaaatca
     3421 ccgcactttc cttcgtcgtt aacatttcca tataaaccac gtattcatca aagattaaaa
     3481 agtttggtgg aagtccaaga aacgcataat tctctcctgt tttgtagttg ggcatttctt
     3541 tcattgcctt gctacgagtc atcatgcgct catagaaatc ttccacacaa gcagaaattt
     3601 cctccttttg ggaatagaca tgaggcatta ccgtacctaa atcggctaag tccgcatttt
     3661 tgggatcaag aacaaaaagc tcggcatcag attttaataa agcctcgatg atagtgagta
     3721 aaaagtaagt cttcccacca cctgtgccgc cagcgattaa catatgaggt aaagaatcat
     3781 aagcccatac ttgatttttc atcaatcgca aagccccact ttctgccact acttcgtcta
     3841 tcccaattcg attggcaatt atatcataca gtaaagtgta ctccacatag gagtctttga
     3901 gttccttttc tactagttca caatatagac cactttctaa cttcttttcc agctttaaaa
     3961 gctgatcttg atattttccc agtgaaattt gaacgcgaat agaaagtaaa ccatccttca
     4021 tacggtaata gattttgggg aagtaactga ttgtctcttt ggttcgacta ctattgaggt
     4081 ctttgaaaaa tccttcactc tgagtttgtt ttacttcgta ccaatgattt tctagaatca
     4141 tccgggctag cttttgtcga tgccacaaac tgcgccaatg atcctgaaaa aagtgtatat
     4201 aaagcaacat cgtgcttcct gaaagaacga gacttcctag caaatagatt aaatctttta
     4261 tagaacgaac gatttctata gtagaaagtg atagcttaga aatatcaaat tgtctaagct
     4321 cttgaaaata aaagacgctc atccaaccga tgaacagagc gagtagccag ccaagaacaa
     4381 agtgataaac caagtgctga tctcctgccc gtatacgatg ccctttgtac atttttatgg
     4441 tttccacctc caatcgaaaa aagcttcata ggatttcatt gatccaattt caagcagtta
     4501 tgctagtcat ttactgctat agggagttgt ttcgtttcca ctagttgctt taaaaaaact
     4561 tcaatggcat ccggcatttc cacaccaatt tcttccaata cggtttcggc ttctcgacat
     4621 agactttcat ttacttcgat aaccataaag aaggactctt cttcccctaa ccaattcagt
     4681 acatcaaaat cttcttcggc atcgttacct acttccagta acccttgatg cataatcaga
     4741 aacatttttt catcataggt taatgcttta gtgagttgtt cctccgttag ctcacctttt
     4801 ccatattgat cgagacaatc taaaatatgt tcaacattaa tttccatacg cttcacctat
     4861 ttctttcctt cattttggtt tgtagaattt ccctgatctg gttgtcgttt caagactaaa
     4921 tcatcggcct taatgaacca attgacagta gttccttctc ggaaaacata attggcgacc
     4981 gtatccatga ttggattgac caactctacc tctgcgtcat aggcaaactc gcgtaagggt
     5041 acatttgctg ggatactaac ttggatcatt cgaccttgcg cagaggattt caaattataa
     5101 gtccgttctt ttacctcgtt actaaccgtt ccatcctcat tttgcttccg tacttctcgg
     5161 cgtaatgcgg aaaatcgtaa tttcccaaac gttagtcctg aatctacaac aataccttct
     5221 gttaatctca tcttcttttc ctcctatgct ttcactaaat catcgacata caacacgtag
     5281 tcggtaaacc cacgattctc aatctcatag cctttggcaa ccaaatgggg attcacggct
     5341 tttagtggtt gatcttgatc aaaatccttt tcgccggctt ccgcagctac caccacttca
     5401 atatcatcgg ctcgttgctt actggaatac aaatgataac tacgaccaat tactgtagta
     5461 ttccgcccat atccttcagt taaaacttcg ccttcgccgg cataccttat ctttccaaag
     5521 gtttcggcca tatctggcac aacaaatttc aattccatct tcttttcctc ttttcatttt
     5581 tagttttgga tacaaaaata gcgcgaccac tttttttagg aggcggtcgc gcacgttggt
     5641 ttttcctatt tagttgtttc atcacatcac cttagtttcg gcgattccag aaataatacc
     5701 cagcagtcgc aaagatcaag gtaaacccaa taaacagcag aacattagaa tttttctccc
     5761 ctgtttgtgg gaatgtcttt actgtaggac tagattcttg agagtcactt ggaacagttg
     5821 gtatttccgg ttgttctggt gcacttggtg ttgtcggaac ttttttaggt gttaaagttt
     5881 gagttttttc ttttagatcc tcattgtgtt tcccattgat gtttccgtct ttgccatagt
     5941 taatttcttt gaaggtaaaa cttgtacctt ctggatattt acttgtgtcc actttttccg
     6001 caagtacggt tttagtgaat tctttgtcat tcacttcata atcaattttg ccagatttcc
     6061 aaatttcttt ggtcgtatta tccggaagta atgcatacag aattgtttca aaagcttctt
     6121 ttgagccatc cagtacatca tgggtaatcg acacatcatc gaacatatcc accacatccc
     6181 catgagtaaa ggtttgcgaa ccatcttcta ggtgggcttt tgtttggatg gaaacatggc
     6241 gttccaccgt acaattgaca gtttgggctt gattgttcaa gctagcatct ttcgctactg
     6301 gatcatcacc tgcttcatag ggtttcttgt tttcatacac atagttgaat aagacgatgg
     6361 ttttatccaa aacttgttct gcggttaatt tatgcaaaat tttccaagtt cctgttttct
     6421 ctttattcgc caacgttgcg gttgtttcgg caattaccac tggtttggct ttttcatctt
     6481 tttcttgggc agcttttgtc gcttccacat caatggcttg cgctaccaca taccagtctt
     6541 ctttgatttc atgcaagtta tagctcaatt tatcaactag ctcggtagaa tcaaggtctg
     6601 tcaattcttt gcctccgtct ttccaagtcc caagagaagt taagctatct tcttcttcag
     6661 gtaaatcata gagcatcaaa cgattcaagc taacagaaaa tgctttattc gtcagtttct
     6721 cgtaaggaac ggtcaccgtt ttaattggtt gtttttgtcc tttttcggta atcgtaaaaa
     6781 tgtattcact cttagtgtaa tccgctttat tttctttaaa agtagaacgg atttctaatg
     6841 gcgtaatttt ttgaaatcct tctggagcct ctacttcttc aagtaaataa tccccataag
     6901 gaagattttc aaacttgcca tagccatcaa aacctagttg ctcgttataa gctgtaattg
     6961 cttcatcttc ggcacctgta atctcactgg ttccttccaa tggcgatact ttaaaggtca
     7021 gatcattgaa gccagtttcg gcagtcccag cagctgatcc agcaaattta aagaaatcaa
     7081 agccaaagcg aatgacttgt tcttttgccg taacatctcg ggtaatcacg gcattttttt
     7141 cgttatcatc cacctttttg atggaaacag ggtactttgt ttcatccaag gtatatcctt
     7201 caggtgcttt ggtttcttgc cagtaatact cattaatcgc taagtgttta acagcaactt
     7261 gattcttttc atctaaagtc aaagtcaccg tttcatcaga agctttcgtt cccttcacta
     7321 actctggttt aaaagcctca ctccatttga ccgcttgacc atcttttgca gtaaagagag
     7381 tatattcagc tcctttaaac tcagctttac cttgagtttc attaccggta tctttgtctt
     7441 cttttgtcaa agtggtttca ccagtgattt cttggttttg cccttttacg ttactggtaa
     7501 caagagccac ggtttgattg acatagttca attcgacttt tactggttta aaggtattca
     7561 caaagccatt actagctttg gtttcggtca cataataggt tcccaattcc aacgcattgg
     7621 caatctcttt tggtgtttcc gcatgacctt tttcatccgt ggtcatttct tggacaattt
     7681 caccggttgg actgtctttg cgaatggcaa acgtatttcc ggctaatgag tatttgtcgt
     7741 tccaaagatc agttcctgtt tccaccccca ttttattcaa aatgatttga cctttttcgc
     7801 gagtattttt tgaagtcaca gaaatagtct caccagattt aatggttgcg gtgattggtg
     7861 tagtgtcaat cgtataagga gctggcactg atttttcagt aatggttact ttcgcgccat
     7921 gaggaatctc atccaatgtc gcaatgcctt ctttatcggt ggtcacgtct tttgcaggta
     7981 atgtttttcc aaagtctaaa tggaaaacgg ttcccggtac aacatttcct gtttctttat
     8041 cgactttttt aatcttcaaa gaaccctcag tttccacatc aattttgatt gtgtaggtat
     8101 tgggcttatc aattgccccc gccatcaaag tttgttgacc agccatttta taagctaccg
     8161 gtgttcctgt attagctgac ttctttaggg ttaattcacc actctctttt gaattggcat
     8221 ttggagtaat cactagttga ttgccgttca cacgataatc aatatttgcg atattctcga
     8281 caacttcatc aaactccgat aaattcaagc cgttcgtatc tgtcacagta gtcgattgac
     8341 ctaacacggt tttcactgtg gagttatgga agcttggttt cttttgataa tccgcaatgg
     8401 cttgattgat ttttgactca atggctgcga tatttactgc actaccatca gaacgtttaa
     8461 ttgagtgaag cgtagccatt aacttcttgc caaatcatct tctgggccac aatatgtgta
     8521 tccacatccg taccagcttc cttccataaa acggaaacta atttcgcttt ctccgacata
     8581 tcaggcaatg gatttttctc ataaccagga gtgaactcat tgtaaatcgg cacccctggc
     8641 tcaatacaga aaatatcttg cttcacacca ttgtaaactg catagtgcgg aacggtaact
     8701 tctgacatgg gacgaccatc gctaaatgta ccttcgacag catactggtg agccaaatcc
     8761 aattccacag ttaccgtttg tggatgagta atttcatcag caaaggcaat cgttgggcca
     8821 agcgatccac caattgtttg gcataataga ctcagtgttg cgagcaaacg ccaattctta
     8881 aatcttggct ttttcataaa ataaatctcc tttcgttttt gggtaataaa aaagacgtcc
     8941 aaattttaat tttgaacgtc tgatttagag tgatactatt tagttttctt tgtcttggat
     9001 aggttgtttc tctgcttata aattttgatt cttcgataat caaatccaat ctctgccatc
     9061 aattcctccc aatttttgtt cgttcttttc ataattgtat caactgatgg tagttttggg
     9121 gattgaacta gttttcgaaa ctttgtcatt gataaatcat cctgtagttt taatcggatt
     9181 atttcatttt ttagttctaa cagcagttcg aaatcagtaa atcgagatcc atcatttttt
     9241 tctttaaaaa gtggacgtat atctcctaac atctttttaa tggtactaag tgaaggaata
     9301 ttcttcccta ctgatttttg ttcgtacatt cgttgagagg ttatcttctc gcacttaata
     9361 aaggcttcta ctatttccaa taattcttgt tctgacattc tagcccattt tccataccca
     9421 gtattttctc gtcctatact aatcaataaa ttctcccatg atccatattt tttgttaatg
     9481 aaccacatac ttggtgcaga atttggattt tctgatagct ttttctggta ttgacggcta
     9541 gatgtaattc cgtgtttttc gatgaattca ttaattgtta aaatcagttt taactcactt
     9601 tgatttttcc aaatgatacg tccatcattt tgcttcacga taaaaactcc taatagttat
     9661 ttagatagaa gcctatcaca tcaacttttt agtagaaaag tacatgtttt gtcttttttg
     9721 ctaatagctg accctttgag aaacttgggt tcaaaagttg ctaaattcgg taaatgtttt
     9781 ggtatttttc gtattatatt tgtcgtcaag ctgactacta aattttgccc tattttgacg
     9841 acactgatag tcaatgtcgg acaatctagg acaattttta agggaatatg attgaaaaat
     9901 ggtccaaaac agccaaaaat ggcttaaaac tgtgatagag aaaaaagaaa aagcccttga
     9961 tatacaagga cttttcacaa atttcagatt tccaaggaag ttttccgtgt ttatcttctg
    10021 atttctttga tacgagcagc ttttccgtgt aatgcacgta aacaaaacca ctatattcta
    10081 ttatgtatct aataccctca aaacagctat aaatcaacaa taccgacata taataaacac
    10141 tatgttcaat ctgagatata tcaaagataa acgtattttt gccccctttt tgcccctcaa
    10201 atatcgcttt acaacgagaa cgtaagttcg tataatcgtt ttgaggtgat ttttatgatg
    10261 gaagacttta ttagaaaaaa tatcagtgat gaatatgcag acttttatga gcaaagcagc
    10321 aaaaaagata aattccagat ggatgtttca attttagcta tattagcttt ttccgaaaat
    10381 aaacaacctg taactgcaaa aaaagaaaca gtattctctg aaggcaaaat aaaaactcga
    10441 tatatattag aggtagaaac taattttaaa aacagatcgg agtaatggtt atgcttttta
    10501 atgagacaca attatggttt aaattcgatc ctacgaatag atttatcaaa gatttttata
    10561 aagtatggaa ttcagaagtt ttctttttag caatcgaaga tagcttatta atcaatctct
    10621 actattctaa taagaactat ttcaaaattc ctgctgcgaa aactagaatg aagaagggtg
    10681 tatacttttt gtttgatatc gtgactgacg tgccggacgc acgtagcgat catcggcgtt
    10741 atgactatat aaagtatact ttcgttgatc cagaaagata caaagattaa ataaaaaaat
    10801 aacaaacaaa ctcgctt
//
LOCUS       DACGDM010000087        10607 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.093, whole genome shotgun sequence.
ACCESSION   DACGDM010000087 DACGDM010000000
VERSION     DACGDM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.093"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            34..657
                     /locus_tag="IXR05_002279"
     CDS             34..657
                     /locus_tag="IXR05_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260755.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /locus_tag="IXR05_002280"
     CDS             1107..2156
                     /locus_tag="IXR05_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4260756.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="IXR05_002281"
     CDS             2153..3034
                     /locus_tag="IXR05_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4260757.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="IXR05_002282"
     CDS             3037..3807
                     /locus_tag="IXR05_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4260758.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="IXR05_002283"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="IXR05_002283"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAQ4260759.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="IXR05_002284"
     CDS             5118..6281
                     /locus_tag="IXR05_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAQ4260760.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="IXR05_002285"
     CDS             6398..6808
                     /locus_tag="IXR05_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4260761.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="IXR05_002286"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="IXR05_002286"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4260762.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9348..9665
                     /locus_tag="IXR05_002287"
     CDS             9348..9665
                     /locus_tag="IXR05_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260763.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9825..10061
                     /locus_tag="IXR05_002288"
     CDS             9825..10061
                     /locus_tag="IXR05_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4260764.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10058..10456
                     /locus_tag="IXR05_002289"
     CDS             10058..10456
                     /locus_tag="IXR05_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAQ4260765.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3708 a         1771 c         2238 g         2890 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatacc gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc tgcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg tccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caagcatttc
     9421 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
     9481 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
     9541 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
     9601 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
     9661 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
     9721 ttcgtaagaa aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata
     9781 atgtacttac tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa
     9841 agtataaaat tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag
     9901 aattcatggg tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg
     9961 tacgaatgat caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga
    10021 atcaatatga agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga
    10081 aattatcaaa atcaacgcga aagttatttt acgtcactcg ccaggcgaaa tgatcggtgt
    10141 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
    10201 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
    10261 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
    10321 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat
    10381 taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca
    10441 aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta
    10501 aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg
    10561 aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaa
//
LOCUS       DACGDM010000088        10408 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.094, whole genome shotgun sequence.
ACCESSION   DACGDM010000088 DACGDM010000000
VERSION     DACGDM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.094"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(83..1819)
                     /locus_tag="IXR05_002290"
     CDS             complement(83..1819)
                     /locus_tag="IXR05_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAQ4260766.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(1816..2520)
                     /locus_tag="IXR05_002291"
     CDS             complement(1816..2520)
                     /locus_tag="IXR05_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260767.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            2651..3154
                     /locus_tag="IXR05_002292"
     CDS             2651..3154
                     /locus_tag="IXR05_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAQ4260768.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            3114..3452
                     /locus_tag="IXR05_002293"
     CDS             3114..3452
                     /locus_tag="IXR05_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAQ4260769.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            3473..4891
                     /gene="ffh"
                     /locus_tag="IXR05_002294"
     CDS             3473..4891
                     /gene="ffh"
                     /locus_tag="IXR05_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAQ4260770.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            5003..5581
                     /locus_tag="IXR05_002295"
     CDS             5003..5581
                     /locus_tag="IXR05_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAQ4260771.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            5585..6106
                     /locus_tag="IXR05_002296"
     CDS             5585..6106
                     /locus_tag="IXR05_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4260772.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(6185..6739)
                     /locus_tag="IXR05_002297"
     CDS             complement(6185..6739)
                     /locus_tag="IXR05_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4260773.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            6992..7267
                     /gene="rpsP"
                     /locus_tag="IXR05_002298"
     CDS             6992..7267
                     /gene="rpsP"
                     /locus_tag="IXR05_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAQ4260774.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            7279..7530
                     /locus_tag="IXR05_002299"
     CDS             7279..7530
                     /locus_tag="IXR05_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4260775.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            7655..8446
                     /locus_tag="IXR05_002300"
     CDS             7655..8446
                     /locus_tag="IXR05_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260776.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            8616..9137
                     /gene="rimM"
                     /locus_tag="IXR05_002301"
     CDS             8616..9137
                     /gene="rimM"
                     /locus_tag="IXR05_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAQ4260777.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            9127..9888
                     /gene="trmD"
                     /locus_tag="IXR05_002302"
     CDS             9127..9888
                     /gene="trmD"
                     /locus_tag="IXR05_002302"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAQ4260778.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            10024..10371
                     /gene="rplS"
                     /locus_tag="IXR05_002303"
     CDS             10024..10371
                     /gene="rplS"
                     /locus_tag="IXR05_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAQ4260779.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
BASE COUNT         3445 a         1929 c         2160 g         2874 t
ORIGIN      
        1 agtaaaaaag aacaaccact cgtgtatctt tcgaagcagg atgagtcatc caactttaaa
       61 acgcacgagc agttgctctt ttttacattt tcggaatggt aacggtgaaa gtcgaacctg
      121 ttccaagatg actgtctaca gtaatcgtac cattaaggag ttgcacgtag tcttttacaa
      181 tcgctaaccc taatccggtc ccgcctgaat gtcggcttcg cgccttgtct acgcggtaaa
      241 aacgctcaaa gatccgttcc tgatcctcaa tgtcgatacc tataccaaag tcttggacag
      301 aaaacgatag atcatctgtt gcctgatagc ggataataat ctcgctgtcg ctttttgaat
      361 attggacagc attttcaatt agatttttga taattggata aaggatatct gttttagtag
      421 taaatggttc gttctttcca atcaatcgaa tcgtcaaccg tttcttttcg atgattggct
      481 gataattttg aacgatttgc tggaaataag gttctgtata aattgtctgg atctcgtaag
      541 aattctcgcc atcttttgac agctggatga tttcccgaat cagtttatct aaccggatcg
      601 catctttttg catgatctca agaaaagaag tcagagtttg cgggtcatct tttgcaccat
      661 ccagtaaagt ctcggtaaaa ccaatcagtg aagtcacagg agtttttaat tcgtgagaga
      721 cgttgccaac gaaatccttt tgtagctttt ctaaacgtcg cactttcgtt aagtcatacg
      781 ccacccctag aatctgtccg gtaccttctg aattagtaaa gtagcgcaaa ctcaagtcta
      841 atgtctgccg accttctgta agggtgatct cctgatggat cagcggatgc tcaggagtca
      901 cttgatgaat cagctgaatg agttttggct cttgaatgac ttctgtgtac cgctgttcag
      961 gttgatagct taccacgttt aaatgtagct gcatctttgg attaagcagt agtaaacgag
     1021 aatcagcatc atcaatcagg aatacgccaa tcatcagttc gttcagtaac gtatataatt
     1081 gctcttctgt ggtagtacac gcccgataca tcttactcat ttgttcgctc aacgcattaa
     1141 tcgtctgata caattcttcc cattgatcgg gtgtttgcat gattacttcc gcctgattag
     1201 gattttgcac catttttttt agtacgggca gcacggtttt caatggctgg tttttttgat
     1261 agatcagata atagatcatt cctgcaagaa caaggaagaa agacagaaag aagaaaaaga
     1321 cccaacggcg aaaactctca gttctcggta aaaaaccgct tgtcggttct gcgatacgta
     1381 aaatggcttc taactggcca ctttttttga ctggtaatgc gacatataaa agatcctcat
     1441 tcaaagtagt acttttgcgc aaagcgctac ctaggttccc accattcaat acggctttga
     1501 tttcgggacg ggagtttcgc tgttcattca atgtttcatt gtttgtgtca aataagatct
     1561 ttccagtagc atccattaaa gtaatccgtt cgttcgactg atggacgaat tcttccaaag
     1621 cagttttgtt ttgcgctgct tggaggtttt cgacatctaa ttgccggatc agcagttgtg
     1681 ctttttttgt caggtagctt tcttgctgtt ccacgatctg ctgttgaaaa taatgggaaa
     1741 tcaattgcca gccaccaaaa aacaaactaa ctaaaagaat aagaaagaag agacgttcat
     1801 aaattttttt ccatttcatc gtttgggttc ctgaaactta tagccaaatc ctctaatagt
     1861 caccaagtac tttgggtgtt ttggatctcg ctcgattttt tctcgcaaat gactaacgtg
     1921 tacatctacg attcggcttt gtcctgcgaa gtcaaaattc caaatgcggt ctagcaatgt
     1981 gtctcggtcg atcacacggt cttttcgttt catgaaataa acaagtaatt caaattcttt
     2041 cggtgttagt tcaatcagat ggtcgtctac ggtcacttga taattggtca aatcagcagt
     2101 gatttgtcca atcgatagat attcaggctc agcttcatct tttgattgct tacgaggttc
     2161 aattcgtctg aatattgctt tcatacgggc taatacttcg cgaggactaa atggtttggt
     2221 caaatagtcg tcagcaccta tttctaggcc aatgatccga tccacttggt catctttagc
     2281 cgtcagcatc aaaatcggtg tttcattttt ttcttgacgc agccgctgag tgatctccat
     2341 gccatccatc gttggaagca tcacatctaa aatgatgaaa tcaaatgatt gttctaatgc
     2401 taattctaat ccttcgcctc catctgtggc actggttacc ttgtagcctt ctttttccaa
     2461 attgaacgtc aagagcgtta caatagaagg ttcatcatca acaactagta tttttttcat
     2521 tcaaatctcc tttaaatagg tttcattctg tttatatttt agcatagaat cagtacaaag
     2581 ggctatttta caaaagaaat aaatggtata ataggaaggc actttgctga atagaaagga
     2641 agagcagtca atgattggaa tcagtgcatg tttaggcggt ctggcctgtc gctatgatgg
     2701 acagaaaaaa gaagtaccag aattgatgga actagttgaa actggagaag ctgtcatggt
     2761 ctgtccagaa gtgatcggcg gattaccaat tcctagagat cccgctgaaa tcattggtgg
     2821 aaatggattc gatgtgtgga aagatcaagc aaaagtatgg acgacaagcg gcgaagatgt
     2881 aacggaagcg tacaaaaatg gcgcgatcaa agcctatcaa aaattgcagg aaaaacacat
     2941 tgatctagtc atcatgaagg aaaaaagccc ttcatgcgga acccattcga tttatgacgg
     3001 aagtttttcc ggaataaaaa aaaatggtgc cggagtggct actgcttatt ttattcagca
     3061 aaaaatgact gtgctctctg atgaagaatg gctgaaaact agaggtgagc agaatggaaa
     3121 tcgaaaagac caatcgaatg aacgcgctct ttgaatttta ttcgacctta ttgacagaaa
     3181 aacaaatgaa ctacatggaa ttatattatg cagatgattt ttcattaggt gagatcgcgg
     3241 aagaatacga agtaagccga caagcagtat atgacaatat caagcggaca agcaagatct
     3301 tggaggatta tgaaaaaaaa ctccatcttt tttctaatta tattgttcga gaacaggtat
     3361 tggaaaatat gactgcatat attacagata agtacccgga agataaaaaa ctacttgaat
     3421 atgtacagca aattcaagca atcgaagaat aaataaaagg aatgaagaaa atatggcatt
     3481 tgaaagctta actgaacgtc tccagcaggc gatgggaaaa ataagaaaaa aaggaaaagt
     3541 atcagaagct gacgtaaaag aaatgatgcg ggaaatccgc cttgccttac tagaagccga
     3601 tgttaacttg caagtagtca aagattttac taagcgcgta cgcgaacgtg cggtaggggc
     3661 agaagtgctg gaaagtttat cacctgcaca acaaatcgta aaaatcgttg atgaagaatt
     3721 gacgatcaca cttggttctg aaacagcaga gttaaataaa tcaccaaaaa taccaactgt
     3781 tatcatgatg gctggtcttc aaggggcagg taaaacgacc tttactggta aattagccaa
     3841 ttatttaaag aaaaatgaaa atgctcgtcc gctcctaatc gcaggggacg tatatcgacc
     3901 agctgcgatc gaccaattga aagtattagg tcaacagcta gacgttcctg tatttgatat
     3961 gggaactgaa gtcagcccgg tagagatcgt ccgtcaaggg atggagttag caaaagaaaa
     4021 gaaaaacgac tatgtattga tcgatacggc aggacgtctg catatcgatg aaacattgat
     4081 ggatgagttg aaacaaatca aagaattgac gcaaccaaat gagattttgc ttgttgtcga
     4141 tgccatgact ggtcaagatg ccgtcaacgt agctgatagc ttcaaccagc aattaggtat
     4201 tacaggggtc gtcatcacta aacttgatgg ggatactcga ggcggggcag cactatcgat
     4261 ccgctcagtg acaggcgcac caatcaaatt catcggttct ggtgaaaaat tgactgactt
     4321 agaagtattc cacccagatc gtatggctag ccgtatcctt ggtatggggg atatgctgac
     4381 attgattgaa aaagcgcagc aagactacga cgagaaaaaa gcggaagaac ttgcacagaa
     4441 aatgcgggaa aattcattcg atttcaatga ctttattgaa cagcttgatc aagtgatggg
     4501 tatgggccca ctggaagatc taatcaaaat gatcccagga atgaatcaag tccctggaat
     4561 cgaaaacgtc aaggtagatc caaaagatgt tgaacgcaaa aaagcgatgg tttattctat
     4621 gacgccagca gaaagagcaa atcctgatct gttgaaccca agccgtcgtc gccgaattgc
     4681 tgccggttct ggaaacagtg ttgttgaagt gaatcgaatg atcaaacaat tcaaggaatc
     4741 aagaaaaatg atgcagcaaa tgtccaaagg ggatatgaac atcccaggta tggaccaaat
     4801 gtttggttca ggcgtcaaag gaaaactagg caaaatggcg atgaatcgaa tgatcaagaa
     4861 aaataagaag aaaaagaaaa aacggaaata agatgaaaaa aacagcttcg gtacagactg
     4921 aaaatgtcta ctgccggagc ttttctatca gcaattttta ttctttacta atacaattac
     4981 tctaaacgaa gaggtggcac agatgagatg tccgtggagt gaacaaacag aaagtatgcg
     5041 gcaatatcat gatactgtct ggggtgttcc tgaatatgat gaccaaaagc tgttccgaaa
     5101 attgatgctt gatattaatc aagccggatt gagctggcag acgattttaa ataaaagtga
     5161 agcattcgat gaagcatatg atcgattcga tatcaaaaaa gtcgcaaatt atggagaaac
     5221 aaaaatcagt gaactaatgg aaaacaaagg aattattcgt aaccgaagaa aaatcgaagc
     5281 agccgtccaa aacgccaaag cagtcttgaa aattcaagaa gaaatcggca gtttttcaga
     5341 gtatctttgg tcgttttcta atggaaaaat cgttgattct tcttatcatt cacaagaaga
     5401 agtcccaaca acaagtcctc tttcagatga attagcaaaa gatctaaaga aaagaggatt
     5461 taaatttatc ggaagcacaa caatctatgc ttttttagaa gctgtcggga tcatcaatga
     5521 tcaccttgac agttgtttcc gcaaagaaga ggtcgtacgt atcggcagaa agggcgaata
     5581 aagcatgcga aaaatcatat tttatggtgc tataagttta gatggctatt tggcaacgaa
     5641 aacggatgat cttcaatggc tttttgacac tccaacaggt aagcaaacta cttatgaagc
     5701 tttttatgaa acaatcgata cgaccatcat gggcagaaaa acttatcagg aagcaaaaaa
     5761 atatttggag accgaagcaa tttatccaga gaaaaagaat ttcgtttttt ccacccacgc
     5821 acaattacaa ttgccagatg ctgaggtcgt aaacgaagat cctgttgctt ttctaaaaaa
     5881 tctacaaatg acagaaggaa aagatatctg ggttgtgggt ggcggtcgat tgatcaaacc
     5941 gctattggaa catcaaatga ttgatgaatg gtatatccag attacccctg tattattagg
     6001 ggacgggatt cctttattcc aaaaaggaac atatgaagcg cgttttgaaa tgctagacac
     6061 gacacgattc ggtgaattta tcgaattgca ttatgtacga aagtagaagt aaataaaata
     6121 aaaaaggcaa ctatatgcag aaatgtcctg tacatagttg ccttttttat taccgttatg
     6181 ctttttactc tgttaatttg ttagaaaaat ctagatacgc atctaaaatc gtttggaaga
     6241 aacttaatgt tccttcaacg atattaccat tttcatcaat tagattcgca acgtttccga
     6301 tatatgcttc cggttgctgc aaggttggca cattcaaaaa gacaagtgat tggcgtagat
     6361 ggtggtttgc gccaaagccg ccgatcccac ctggtgatgc agtaacgact aaacctggtt
     6421 tatgatccca aacactgtgt ccataaggtc ttgagcctac atctaaagca tttttcaata
     6481 ctgctggcac agaacggttg tattcaggag taacgaaaac gacaccgtct agtcccctca
     6541 cttcctcacg aaaacgagtc cattcagcag gagcctgttc tggagtttcg agatcctcat
     6601 tgtaaaatgg cagatcatcg atttttacaa atacactttc gtacccttca ggaagcaatt
     6661 tcgcaaaagc ttctgctact tttttgttgt aagaatcttt tcttaaacta ccaataaaaa
     6721 atccaatttt ttttgtcata cgatttttcc tccttcaaac tatctataat aatcttacaa
     6781 aagataagta actggagcaa ataaaaacac ttactgacaa aagctacata gaagatagat
     6841 tacttatttt taacaaaaaa gaagtctaaa atcttctatt ttctaaaaaa aatcgaattt
     6901 aatcaagctg taaagaaaaa aagctttaca gggtaaaaaa aaactgttac actacatctt
     6961 gtgaataaaa caatggaggt ggaaataaat aatggcagtt aaaatccgtt taaaacgtat
     7021 gggttctaaa aagagtccgt tttaccgtat cgtcgtagct gattcacgtt ctcctcgtga
     7081 tggacgtttc atcgaaactg taggtactta caatcctttg aaagaccctg cagaagtagt
     7141 tttaaaagaa gacttagttc ttgactggtt atcaaaaggt gcacaacctt ctgacactgt
     7201 acgtaacatc ctttcaaaag aaggcgttat gcaaaaacac cacgaagcta aattctcaaa
     7261 gaaataaggt gaccggatat gaaagattta agcgacttag tcttaacaat cgttcgtccg
     7321 ctagtcactt atcctgatca agtcaagtta gacgtcgtag agtcgaaaga cttttacgag
     7381 tacaatctaa cagtggctcc tgaagatatt ggccgtatca ttggaaaaca agggcgtgtt
     7441 gctaaagcaa tccgcacaat cgtttacggt gttcggatca atgcaccgaa aaaagtgcgt
     7501 ttgaatatca tcgatgataa ggaaaagtaa ataaacgtgc tgtactcgaa ttttcgagtg
     7561 cagctttttt gtttttttta ttaattgaag aaatgattat ttggcaaaac aagcaagaaa
     7621 gcgtatcctt ataggaggag ggagtgaaca gccaatgaga aagaaaatgt tatttattcc
     7681 atttgctcta ttgttaagcg cttgtagttc ggttactcaa gaatcagaca atacacatct
     7741 atcaagcagt atatctgaaa ctgttaccag tccagaaaaa agtagtacca aaacggcttc
     7801 caccactgaa caaacaatgg ctacctcaaa taatgagaaa aagactgctt tagaccagtt
     7861 gaaagaacaa cagccaaatg ttcccatgcc tctagatgta ccagtctctt caggctatct
     7921 caatatcgca gcgacacata caaagcaagg ttattctatt ttatattaca gaacagatcg
     7981 tcccctcggg ttgaatgctg acgaattgaa tcaagaaacg cctattgcaa cctatctata
     8041 tcaatatggg tttgcttcta gtcaagaaac aatccaagtt ttgcagccat ttgagatcga
     8101 cacaaatggt cagcaagtgg acttaggttc tcgaatcaca gggtatcagc aaggtgcagc
     8161 aggttcaagt tttcttgaat ggcaagaagg aaactggcgt attcgaatcc gtgggaataa
     8221 tatagaaggc caagatccct tactattagc taaagaaatc gtagcttatt tggaagaaaa
     8281 cagtctacca gcacctgaac aatttggtaa aattactgtt gatatgggtg atacgacgaa
     8341 tcgagccgta gaagtaagct ggcaagaacc gaaaaatgcc tatacgatca ctcatcaaga
     8401 tcctatgtct gcgttgaaga tggcagtttc tatgaagagg ttgtgaaatc agcgcgctga
     8461 tctgagccca tcatttaact ccaagtcaca ggaagtaatc aaaaatagca cgccgcattt
     8521 ttgcataatt ttggcttaat accttaaaag aaaactagaa ttgcctcttc acacatgcta
     8581 aaataaaaca gacaaaaaag aaatggggat ataagttgac tgaatacttg aatgtaggaa
     8641 aaatcgtaaa cacacaaggt atcaaaggcg aagtccgtgt tatctcaaca acggatttcc
     8701 cagaagaacg ttacaaaaaa ggaacggtgc taacactatt ccaagacgga aaagcacctg
     8761 tggaattaac agtcaaaagt catcgcaaac ataaaaattt tgacttattg agttttgaag
     8821 gacatccttc tatcaatgat gtggaaaaat atcgggatgg catattaaaa gtgtcaaaag
     8881 acaactctgt agatctagct gaaaatgaat tctattacca tgagatcatc ggtctgcatg
     8941 tattagaaga tggaactgag ttaggtaaag taaaagaaat cttgtcacca ggtgccaatg
     9001 atgtttgggt cgttcaacgt ccgaaaaaag ctgatatatt gcttccatat atcgcttctg
     9061 tcgtcaaaga agtcgattta gaagctggag tggtccgtgt agaaattcca gaaggactga
     9121 ttgacgatga agattgatgt attgacttta tttccaagaa tgtttgaagg tcctatgggg
     9181 gaatccatca tcggtaaggc tgtagataaa ggattattag atatcaatat ctctaacttc
     9241 cgcgattatt cagataacaa acatcagaca gtagatgatt atccatacgg cggtggagca
     9301 ggtatgctgc tcaaagtcca gcccatctat gataacatcc aagccattga aaaagctgca
     9361 ccggatgtca aaaaaagagt aattcttctt gacccagctg gtaaacgatt cgatcagaaa
     9421 atggcagaag aattttcaca agaagaacac ttagtattca tttgtggtca ttatgaggga
     9481 tatgatgaac gtatccgcac attagtgaca gatgaagttt ccttaggaga ttatgtcctt
     9541 actgggggag aattaggtgc gatggtcatg atcgatgcaa cagttcggct tttgccagat
     9601 gtgttaggga atcagacttc agctcaaacg gattcttatt caaccggttt attggaacat
     9661 ccccaatata ctcgcccggc agaatataaa gggatgaaag taccagaagt attgacaaat
     9721 ggaaatcata aattgattga agaatggcaa ttaaaagaat cactaagaag gacctatcaa
     9781 cgtcggcctg atcttttgga aacacttgaa tggacacctc aaatgacgaa atttttagaa
     9841 gaaatcaaga aagaagaaca agaaaaaaca gcagatgaag ccaagtgact ttttctaaaa
     9901 tcttctttac agtaggttga taatatgtta gtattttatg gtgagtgcaa aagcacttaa
     9961 ctattacgat attccgctgt gagaaaagct cataagaata tttggaataa ggagaagaaa
    10021 accatgaatc cattaatcga agaattaaca aaagaacaat tacgttctga catcccagcg
    10081 ttccgccctg gtgacactgt gcgtgttcac gcaaaagttg ttgaaggtac tcgtgaacgt
    10141 atccagttat ttgaaggtgt tgttatcaaa cgccgcggtg ctggaatcag cgaaacttat
    10201 acagtacgta aagtttctaa cggagtgggc gttgaacgta cattcccatt gcatacacca
    10261 cgtgttgcaa aaatcgaagt agttcgctac ggtaaagtac gtcgtgcaaa attgtactac
    10321 ctacgtgcat tacacggaaa agctgctcgt atcaaagaaa tccgtcgtta atcatcgtta
    10381 tcagactgag aaagaaccct tggtattc
//
LOCUS       DACGDM010000089        10196 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.095, whole genome shotgun sequence.
ACCESSION   DACGDM010000089 DACGDM010000000
VERSION     DACGDM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.095"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            121..627
                     /locus_tag="IXR05_002304"
     CDS             121..627
                     /locus_tag="IXR05_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAQ4260780.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            644..1543
                     /locus_tag="IXR05_002305"
     CDS             644..1543
                     /locus_tag="IXR05_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAQ4260781.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            1630..2514
                     /locus_tag="IXR05_002306"
     CDS             1630..2514
                     /locus_tag="IXR05_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAQ4260782.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(2706..2777)
                     /locus_tag="IXR05_002307"
     tRNA            complement(2706..2777)
                     /locus_tag="IXR05_002307"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2742..2744),aa:Arg,seq:ccg)
     gene            2837..4171
                     /gene="rpoN"
                     /locus_tag="IXR05_002308"
     CDS             2837..4171
                     /gene="rpoN"
                     /locus_tag="IXR05_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAQ4260783.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            4374..5411
                     /locus_tag="IXR05_002309"
     CDS             4374..5411
                     /locus_tag="IXR05_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAQ4260784.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            5452..6453
                     /gene="gap"
                     /locus_tag="IXR05_002310"
     CDS             5452..6453
                     /gene="gap"
                     /locus_tag="IXR05_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4260785.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            6563..7753
                     /locus_tag="IXR05_002311"
     CDS             6563..7753
                     /locus_tag="IXR05_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAQ4260786.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            7857..8612
                     /locus_tag="IXR05_002312"
     CDS             7857..8612
                     /locus_tag="IXR05_002312"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAQ4260787.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            8728..10026
                     /gene="eno"
                     /locus_tag="IXR05_002313"
     CDS             8728..10026
                     /gene="eno"
                     /locus_tag="IXR05_002313"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAQ4260788.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT         3566 a         1886 c         2112 g         2632 t
ORIGIN      
        1 tttttgtcac accttctttt ttgtatataa aaatcccaag taaatacata aaaaataaaa
       61 aaattgaaac ttttagcgca ccttgtacgt catattaagt gaggcagaaa ggagtggaga
      121 atgattttta ctggatataa gaaaaaacgg cagatcgaaa aataccgtca cctgctgaat
      181 ggactcatcg aaactgatta tcaaaaaatg ttccgtatca cgatgaatta cgtacatgat
      241 aaagaagagg ccttagatgt gatgcaagat agttttcata aagccctgaa ctattttgaa
      301 aaagaaaaag agatcgagca ttttagtgca tggttttatc ggatattgat ccgcacggca
      361 ttagatagtt ggcgcagaca aaaaaggacg cctgtggact tatttgaaat tcaagatatc
      421 ccccaacagt tacctttaga aacttccgtt gcagagctcc atatgatttt agataaaata
      481 gacagtccgg aaaaagagat tctgatcctc tacttttttg aaggatttcg tttgaaagaa
      541 attgcgacta tcttggatat gaatgaaaac acagttaaaa cgaaaatgta ccgctcattg
      601 aatgctttac gtcaaatcct agaatgaagg agagaagagt gccatgtatt cccaaaaaga
      661 aaatttaaaa aaactaaaga aaacttataa agaacaagca attcccaaag ggcttaaaga
      721 ggagatccgc cagcgtttta ttatcgaaga gcaatcattt ataaaagcaa agcggagaaa
      781 gagacgtctc caagggttcg gagtatcttt ggctatcgta atgattacaa caagtagcct
      841 tctttttaat agtcaagttc gaagctttgc agaagattta cccatcttag gatcagtcat
      901 tgaattgatc ttaggcgaac gctttactga tcgatctgaa aaaatcgata ttcaggtacc
      961 gaagatcaat acacaaaatg agaaagaaaa taaaacaatt catggattaa atcaaaaata
     1021 ctttcgcgaa ggacaagcag attttgaaaa agctgaaaaa gaatatggaa attttgaaac
     1081 ggatcattac caagttttgg gagattatca gaaaatcgta gacgataacc ggtttctcgt
     1141 gattgaaagg cagatcaccc aaacagcagc agatagccat gttgaaaaaa gatacgacac
     1201 aatcgacaag aaaaacagtg tccagctctc acttccactt ttattcaaag atgacaccta
     1261 tctatctgtt ttgacaaaag aagtcaaacg gcagatggcc gaacaagtca aggaagatcc
     1321 atctaagtac tattggactg agcaagatat tcaagaaggg acgatagaaa aaccaacact
     1381 tgttacgcct acacgaagtt tttatttgaa caaagagcat caattagttt tgactttttc
     1441 tcaatacgaa attgctcctg gttatatggg tacaccagaa tttgtcattc ctaagtccgt
     1501 gacaaaaacg attttggcat cggaagatta tttggatcat tagacgagaa gtagttgcga
     1561 ctagcagttt caattttcaa gtaagtacaa gtaaataata agaagagaaa aagagaaaga
     1621 agagatatag tgaaaagaaa ttatttagtt atcagtatta ttgctttatc cgtgcttttg
     1681 tttttcgaaa ttacttcggt ggcctccttg atcaccgaag taaaaggaca aacacactct
     1741 tcggagcatt cgtcacaatc tttcaaacaa tcagaacaat caaccattaa aagccaatca
     1801 actgaaacag ctaacgtcaa agaagccatt caagaatcag cggaaaaggt acaaagtcag
     1861 tcatcacaat caacacaaga cagtacaaaa acgagccgag atccggctgt caaaagcgtc
     1921 gcaatcagct ttgatgatgg accaggagcg accacaacac cgcagcttct gcgaatctta
     1981 aaagaaaaaa acgtgcatgc cacttttttc gtcttaggag aaaatacggc gcagcatcct
     2041 gaaatcgtga agcagacagc tgaagcaggg cacgagattg gcaatcacac atacgatcat
     2101 cagaatctgg ccactctttc tgcccagtcg atgacggagg aagtgacgaa agcagacact
     2161 gagatcaaaa aagtcactgg caaaaccccc acttttgttc gtccgcccta tggttctgtc
     2221 acgaatgtag gagcaacgat catccagcga ccgatcatcg aatggtctgt tgattcagaa
     2281 gattggaaga caagaaatcc tgatttgatt ttgcagaaga tccaagcaac agtatacgat
     2341 ggggcaatta ttttattcca tgatatctat cctgaaacga ttcgtgccgt tcctcaagtg
     2401 atcgattatc tgaaagagca agggtatcgc atcacgacag ttggggattt attagggcat
     2461 ccaacggctg tcgagaacta ttatggcaga aacgatcatc ggccagttca gtaagtgaga
     2521 caagtatctt taataaataa cacattttaa taagtagttg aacacataac taccttactt
     2581 gcaaaggctt aacaatatct atacaggtac aacaaaaaac tgtccaccaa ttttctttgg
     2641 cggacagttt tcacttaaaa ataaagaagc aactattcgt aaattatgct aaaatagcag
     2701 tagaacgcgt cctgagggaa tcgaaccccc gtctcaagaa ccggaatctt acgtgatatc
     2761 cactacacta aggacgcaag cactgggata attgtaacta aacagataaa aaattacaag
     2821 gggattggac aaaaaaatga aatttgagca aaatttttca caaaaacagc agcagacaca
     2881 gaaactagcc atgacgcaac agttgcaaca gtccatccaa gttttacaat ataacagtga
     2941 ggagctgttg gcattcgttg agaatcaagc aatggaaaat ccattggtgg aagttgttga
     3001 gccggaatgg cagccagatt acataaaagc ttcttcatct tcttatgaag gagaagagac
     3061 aaattaccta aatcagattc ctgatacaaa agggtcttta tttgattcat tgatcgaaca
     3121 agtccatttg aattaccgag atactttttt gaggaaaatc gttctttatc ttgtagaata
     3181 catcgatttg aacggatttt tgacgattag tttagaagaa gccggaaaag agattggagc
     3241 tacgcctatc caaatgctcg atgcgttgac tctgattcag caattagaac cagctggagt
     3301 aggtgcacgt agtttgcaag aatgtctcat gcttcaaaca gaacgagatg attatgcgcc
     3361 ggaattagct tatatcgtgt tggaagaatg ttttgaggaa ctggtggagc gaaaatggaa
     3421 agaaatcgca caacgttttt ctgttgatct acatgctgtt cagcagatat tcgactattt
     3481 acaaacgttg agtccaagcc ctggccggat tttcgaccgt agcagcgaat tgtacattat
     3541 tcctgatgtc cgggtattag tggacgacga taaaaatgta caagttatct caaaccgaaa
     3601 aaatcagcca aatatacgct ttcaagagag ttacttcaaa caaatgtcac aacaagcaga
     3661 taaagaaact gaaaattatt taaaagaacg gaaacaggaa ttcgaatggt tgaagaaaac
     3721 gatcctacaa cgtggggata caattttgcg ggttgctcaa gtcattgttt cccggcaaaa
     3781 agctttcttt atcgacaagg aacgtccaat caagcctctt acgttaaagg aagttgcaac
     3841 tgagatagat gtgcatgaat ccacggtcag tcgtgcagtc aacgggaaat atttggaaac
     3901 agacttcggt gtatttgaat taaaaaaatt tttcactaca cgaattccta cgaatagtac
     3961 agaacagaca gaagaccttt cagcagatac agcgaagaaa aagctgcagg aattagtcga
     4021 tcaagaagac aaaaacaagc cgttgtctga ccagaaattg gttgaattgc tgaaaaaaga
     4081 tgagatagcg atctcaagac gaacagtagc aaaatatcgt gatttattag gaatcccgag
     4141 ttcatcaaaa agaaaacgtt atgataacta atcagtcaaa agactagaaa aagtatttca
     4201 ctttttctag tctttttagt tgaaaaacga gagcaaaact gttagactta cagtcgtgag
     4261 gttgagattt ccctttattg atgtgaaatt cgaatagtta atttcttttt ttatcgtata
     4321 tgggtcgttt taagtctaca ttggacgtaa agtgtccaac taaggagatc gctatgctgg
     4381 atgaaataaa aatgattgaa tctgttgcac cagatattat cgaagtgttg caagaacgct
     4441 ataaaatttt acgaaatatc tattggatgc agccgattgg acgtcgaagt ttatcggaaa
     4501 gtatggggat cacagaacga gtattgcgaa cagaaacaga tcttttgaaa aatctgaatt
     4561 tgatcgacac ctcaaaaagc ggtatgacgc tgacaactaa gggcgaagaa gtttatcaaa
     4621 gccttgaaaa cttcatggat cagcttttag gtacgcatca aaccgaacaa cagttggcag
     4681 aatattttgg taaccaacgc tgtatcgttg tttcaggaaa cagcgaagag cagaccaaag
     4741 tggctgatgc attcggcgaa gcgctgagcg aagccctaga ccgactactt ccagaaggcg
     4801 agaatatcat cgctgtgatg ggaggaacta ctatggctgt ggtagccgaa caattgtcta
     4861 atctggaaaa taagaaacgg cataacctgt ttgtccctgc aagaggcggg attggtgaag
     4921 cgataactgt acaggcaaat tctgtcagtg caagaatggc tgctaaagca aacggtaacc
     4981 accgtgcact ttatgttccg gaacaattaa gtctggcaac ttacaattct ttactcaatg
     5041 agccatctat ccaagaagtc ttaaacttga ttagtgaagc gaattgtgtt attcatagta
     5101 ttgggcgtgc attacacatg gcagcacgtc gtaagatgac tgaaaaagaa ttagtcatgc
     5161 tgaaacaagc aaatgctgtt gcggaatctt ttggctactt tttcaatgaa aaaggtgaag
     5221 tcgtttataa ggtccctaga atcggcatag aattgcaaga tttggaaaaa gtcccgatca
     5281 tcatggcaat cgcgggcgga aaatcaaaag ccaaagcaat tcgagcttat atgaaaaatg
     5341 caccaaaaca aacgtggctc atcactgatg aagctgctgc aaatgagatt ttaaaagggg
     5401 taacccttta aaataaatat ttttttgatt ttcataagga ggaaatctta aatgacagtt
     5461 aaagtaggta ttaatggttt tggacgtatt ggacgtctag cattccgtcg tatccaagat
     5521 gtagatggaa tcgaagtagt agcaatcaac gacttgacag atgctaaaat gttggcacac
     5581 ttgttaaaat acgacacaac tcaaggacgt ttcaacggaa cagttgaagt tcatgaaggt
     5641 tcattcaacg taaacggaaa agaagttaaa gtattagcta accgcaaccc agaagaatta
     5701 ccatggggcg aactaggcgt agatatcgtt ctagaatgta ctggtttctt cacttctaaa
     5761 tcagcagctg aaaaacattt aacagctggt gctaaacgcg ttgttatctc tgctcctggc
     5821 ggaaacgatg ttccaacaat cgtttataac acaaaccacg aaacattaac tggtaaagaa
     5881 acagttatct caggtgcttc atgtactact aactgtttag ctcctatggc taaaacattg
     5941 aacgacaaat ttggtgttgt tgaaggatta atgacaacta tccacgctta cacaggtgac
     6001 caaatgactc tagacggacc tcatcctaaa ggtgacttcc gccgtgcacg cgctgctgct
     6061 gcaaacatcg ttcctaactc aacaggtgct gctaaagcta tcggtttagt aattcctgaa
     6121 ttgaacggta aattagacgg agctgctcaa cgtgttcctg taccaacagg ttcattaaca
     6181 gaattagtaa cagttcttga aaaagaagta actgttgacg aaatcaatgc agcaatgaaa
     6241 gaagcttcaa acgaatctta cggatacaac acagacgaaa tcgtttcttc agatatcgtt
     6301 ggtatgactt acggttcatt atttgatgct acacaaacta aagtaatgac agttggcgac
     6361 aaacaattag ttaaaactgt tgcttggtac gacaacgaaa tgtcatacac tgcacaatta
     6421 gtacgtactt tagaatactt cgctaactta taagatagac aaacgtacaa gtgtaaatta
     6481 tagacatgta catttaaaag cggggaagca atcgcgcttc ttccgctttt tttgataata
     6541 agtttattca ggaggaaata aaatggctaa gaaaacagtg aaagatatcg atttaaaaga
     6601 caaaaaagtt cttgtccgtg ttgacttcaa cgttcctttg aaagacggcg tgatcactga
     6661 cgacactcgt atcaaagcag cattgccaac aatcaactac gttctagaac aaggcggaaa
     6721 agcaatcctt ttctctcacc ttggacgtgt aaaaacagaa gaagataaag aaggaaaatc
     6781 tttagctcca gttgcaaaac gtctaggcga attattaggt aaagaagtaa cattcgtacc
     6841 tgaaactcgc ggagaacaat tagaagaagc aatccgcaac atgaatgacg gcgacgttgt
     6901 cgtattcgaa aatacacgat ttgaagatat tgacggtaaa aaagaaagca aaaatgatac
     6961 agaactaggt aaatactggg cttcattagg cgatgtattt gttaacgatg ctttcggtac
     7021 agctcaccgt gcacatgctt ctaacgtagg tatcgcttca actggtatcc caacagttgc
     7081 tggattcttg atggaaaaag aaatcaagtt catcggtgaa gcagtagaag aaccaaaacg
     7141 accaatgatt gcaatccttg gtggcgcaaa agtttctgat aaaatcggcg taatcgaaaa
     7201 cttgattcct aaagcagata aaatcttgat cggtggcgga atgacttaca cattctacga
     7261 agcaaaagga atcaagatcg gtaactctct agtagaagct gataaagtgg aactagcaaa
     7321 agaattaatc gaaaaagcag gcgacaaact tgtcttgcca atcgacaatg tctgtgcacc
     7381 agaattttca aatgatgttg aaacacaagt aatcgaagga gacattcctg atggtttgat
     7441 ggctttagac atcggcccag catcagtaaa attatttgct gatacattac aaggtgcaaa
     7501 aacagttgtt tggaacggac ctatgggtgt atttgaaatg agtaactttg ctaaaggtac
     7561 aatcggtgtt tgtgaagcaa tcgctaactt agaaggcgca acaacaatca tcggtggcgg
     7621 agactcagcc gcagcagcag aacaattagg atttgctgac aaattcacac acatctcaac
     7681 aggtggcggc gcaagcttgg aattgcttga aggtaaagaa ttaccaggac tagcagcaat
     7741 caacgataaa taaacgacca agtttgctca attctgacga gtaatcgatc aaaaggtgaa
     7801 gggagttttc atgactccct agccattttt caataaatta aggagtgtgt tcctcaatgc
     7861 gtaaacctat tatcgcaggt aactggaaaa tgaacaaaac tgcatcagaa gcaaaagaat
     7921 ttgctgaagc agtaaaaaac aaaatccctt caaatgacaa agttgattca gtcatcggat
     7981 ctcctgcatt attcttacaa gaattaatga catcagctga aggtacagaa ctaaaaatct
     8041 cagcacaaaa ctgctactgg gaaaactcag gtgcgttcac tggtgaaact tcaccagcag
     8101 ctcttgctga tctaggtgtt cattatgtga tcatcggaca ttcagaacgt cgtgaatatt
     8161 tccatgaaac agacgaagac atcaataaaa aagcgaaagc tatctttgca aatggtatga
     8221 caccaatcct atgctgtggc gaatctttag aaacctatga agcaggcaaa actgctgaat
     8281 ggatcgaagg acaaattaca gctggtttag ctgatctttc agctgaacaa gtgtcaaaca
     8341 tggttattgc ttatgaacca atctgggcaa tcggtactgg taaatcagct gacgcacaaa
     8401 tcgctgacga aatttgtgga gttgtacgtc aaacagttga aaaactttat ggaaaagaag
     8461 tatcagaagc agttcgtatc caatacggcg gttctgtaaa accagaaaat attgctgaat
     8521 acatggcaaa agaaaatgtt gacggtgctt tagtcggtgg cgcaagcttg caagcagatt
     8581 cattcttgtc attgttagac gctgtaaaat aattgttgaa aatttgcgaa aaatgcaaga
     8641 aatgtttgca ctaatgagca aaattaacta aaatcgtata tgagggaaat cccttaggaa
     8701 aaaacaaact caaaggagag acaaaacatg tcaattatta ctgatgttta cgctcgcgag
     8761 atcttagact cacgtggtaa cccaacaatc gaagtagaag tatacacaga aagcggagct
     8821 tttggccgcg gaatggttcc ttcaggtgct tcaactggtg aatacgaagc agttgaatta
     8881 cgtgacggag acaaagctcg ttatggcggt aaaggtgtaa ctaaagctgt cgacaacgta
     8941 aacaacatca ttgctgaagc aatcattggc tacgatgttc gtgaccaaat ggctatcgac
     9001 aaagctatga tcgctttaga cggaactcct aacaaaggta aattaggtgc gaacgctatt
     9061 ttaggtgttt ctatcgctgt tgcacgtgca gctgctgact acctagaagt acctttatac
     9121 cactacctag gcggattcaa cacaaaagta ttgccaacac caatgatgaa catcatcaac
     9181 ggcggatcac atgctgataa ctcaatcgac ttccaagaat tcatgatcat gcctgttggc
     9241 gctccaacat tcaaagaagc tctacgtatg ggtgctgaag tattccacgc attagcttca
     9301 atcttgaaag ctcgcggatt agcaacttct gttggtgacg aaggtggatt tgctccaaac
     9361 cttggttcaa acgaagaagg ttttgaagta atcatcgaag caatcgaaaa agctggctat
     9421 gtacctggta aagacgttgt tcttgctatg gatgctgctt cttcagaatt ctacgacaaa
     9481 gaaaaaggtg tttacgtact agctgattca ggcgaaggcg aaaaaacaac tgacgaaatg
     9541 atcaaattct acgaagaatt agtttctaaa tatccaatca tctcaatcga agacggatta
     9601 gacgaaaacg actgggacgg attcaagaaa ttaactgacg tattaggcga caaagttcaa
     9661 ttagttggtg acgacttgtt cgtaacaaac actcaaaaat tatctgaagg tatcgaaaaa
     9721 ggaattgcta actcaatcct tatcaaagtg aaccaaatcg gtacattaac agaaactttc
     9781 gaagctatcg aaatggctaa agaagctggc tacacagcag ttgtatctca ccgttctggt
     9841 gaaacagaag attcaacaat ctctgatatc gctgttgcaa caaacgctgg ccaaatcaaa
     9901 actggttctc tatcacgtac tgaccgtatt gctaaataca accaattact acgtatcgaa
     9961 gaccaacttg gtgaagttgc agaatacaaa ggtttgaaat ctttctacaa cttaaaaaac
    10021 aaataattct tttctaatga agatacatga tcgactattg aaagatagtc gagtatgatc
    10081 acttagttaa gtaatcgaac tctctacttg ctgaaatatc ggctctttgt caataaggac
    10141 tgatgagttg tgcaaaatca aatctgagtc agaatgaacc acattctggc tcagat
//
LOCUS       DACGDM010000090        10086 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.096, whole genome shotgun sequence.
ACCESSION   DACGDM010000090 DACGDM010000000
VERSION     DACGDM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.096"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(247..759)
                     /locus_tag="IXR05_002314"
     CDS             complement(247..759)
                     /locus_tag="IXR05_002314"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAQ4260789.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(773..3070)
                     /gene="recJ"
                     /locus_tag="IXR05_002315"
     CDS             complement(773..3070)
                     /gene="recJ"
                     /locus_tag="IXR05_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAQ4260790.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(3212..3646)
                     /locus_tag="IXR05_002316"
     CDS             complement(3212..3646)
                     /locus_tag="IXR05_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAQ4260791.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(3656..4444)
                     /locus_tag="IXR05_002317"
     CDS             complement(3656..4444)
                     /locus_tag="IXR05_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4260792.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(4441..5382)
                     /locus_tag="IXR05_002318"
     CDS             complement(4441..5382)
                     /locus_tag="IXR05_002318"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAQ4260793.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(5559..6146)
                     /locus_tag="IXR05_002319"
     CDS             complement(5559..6146)
                     /locus_tag="IXR05_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAQ4260794.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(6367..7680)
                     /gene="obgE"
                     /locus_tag="IXR05_002320"
     CDS             complement(6367..7680)
                     /gene="obgE"
                     /locus_tag="IXR05_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAQ4260795.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            7968..8978
                     /gene="gap"
                     /locus_tag="IXR05_002321"
     CDS             7968..8978
                     /gene="gap"
                     /locus_tag="IXR05_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4260796.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(9063..9998)
                     /locus_tag="IXR05_002322"
     CDS             complement(9063..9998)
                     /locus_tag="IXR05_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4260797.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         2778 a         2298 c         1746 g         3264 t
ORIGIN      
        1 ttttacgggg gtgtgacaaa aatcggtcac atcctttttt tcgaataaac ggtgttctaa
       61 agccagtttt tcggtattaa gtcaaattgc ggaaaaagtg attttttaaa cttctactgg
      121 tctttgcttg tttccattta taaaaaaata gcgaccctca aaagtcagat agagaatctg
      181 acttttgagg gtcgctttaa aatcgcttct ttaagaataa catcaagaat agcttctttt
      241 ttctgcttaa tattccatta atgtaatgat gtcatatcct ttgattttgt cgcgtccatg
      301 gagatccatc aattcgatca aaaatgcgca gcctacgact acaccgccta attgttcgat
      361 cagttcgatc gtcgctttga ttgttcctcc agtagctagc aaatcgtcac aaatcagcac
      421 acgttgacct ggtttaatgg catccttatg caatgtcaat gtatctgttc catattctaa
      481 tccataagtc acttcgatgg tttctcgagg taacttccct tttttgcgga ctggggcaaa
      541 accgactcct aactcataag caacaggaca tcctacgatg aatccacggg cttctggccc
      601 aactaccata tcaattcgtt tttcttttgc ataatttacg atttgtttag tagcttcccg
      661 ataagcgtca ccatctgcca tcagtgggga aatatctcga aacacaattc cttttgacgg
      721 atagtcggga atactggcaa tataatcttt taaatccact ctttgtttcc tcctaggttg
      781 ttaaccattt ctttatggta ggaatatcgc tcaaaagcaa aaattcctca actttgattt
      841 tattgagccg tcgctggtat aatctgctct cagtcaaagg atgactttct gggctagcga
      901 ctttttgtaa aacaccgttc tctattgtaa caaatttcaa ttcaaaaaac acctgtatca
      961 taaaaattaa taatttttca gggatacgca aatattgagc tattgctttt attttatgac
     1021 gtatatcaat tcgttcttga gaatggatca atttaaacaa ttttgcgtac tgttctcttg
     1081 tgcctacccc attcaaatag gcctcatcag gtgaaatccc catcagataa acacgattga
     1141 atgaataaga ccgaaaaact tctttcagat ccgctaaatc atctggacaa tccataacaa
     1201 ctagagagtt tggttttctt ttttcaatta ttgcctttac agaatctagt ccttcgaaaa
     1261 caatcgcagc ttcctggata atctcaggca cgaatttcaa cgtcgaagaa tcaaatgcta
     1321 aataaaggct accttccgac gttcggctct gttcacggaa acgttttgcc cgccaatcaa
     1381 atacttgcag accacccaca gaaaaatcag ataccatcag ctgcggtttc ttacgcccgt
     1441 tccattcatt gatcgaaagc tttcctacca catctacctg attattcagc agttcttctt
     1501 cttgagtacc aaaaccaaaa gcgaccgcat caagctgact cgatgcatcg gaaaggacaa
     1561 atttcagatg ctgttggttt gctccgattc ttttgatatt ttctgcttgg acttgtcgaa
     1621 ataaaaactg aggcaaagga ttatccgtac caaatggcgc caatagtttc agctcatcaa
     1681 ttcgctctac tgttacttca tttggcagca atacttcatc aattctcaac tcaggccctc
     1741 tcatcaagtc aatttgatga tcgactatat attggttcat cttctcctgt agtatagtga
     1801 cattttcact tggcatcgtt aaaccgactg ctgcatgatg tcctccgaag taagtaaata
     1861 aatctcgcat ctggtcaagc atttcaaaaa gattcaaggc ttcaatacta cgtccagatc
     1921 ctttagctga tccatcttct tttaaagtaa ggacaagcgt tggtttaccc gtttcattca
     1981 ttattttccc agcaacaatg cccaaaacgc cttcatgcca tcctcggttt accaatagat
     2041 ggatatgatt ctccttattg accatcgcta atgcttcttg tgttatctgc tctacgattg
     2101 cttttctttc ttcattgatc tcattcaatt tttttgcttg aacggatgct tcctcttcat
     2161 caaacgtcgc aagtaacgag acggcaggac gtggatcgcc catccgaccg attgcattta
     2221 gtctgggagc aatcgaaaaa ccgatcgttg tttcgtctgc gtccctcatt tttacgccgc
     2281 tttcttcaaa tagcgcctga agtcctatcc gttctgaatg atgaatggca tcgattccta
     2341 atgaaacaag gattcgattc tcatcagtca atgaaactaa atcggcgatc gttcctatcg
     2401 ctactaaatc caaaaattct gcaggcggtt cttccaataa tgcagaagct actttgaatg
     2461 ctactccgac tcctgccaaa tctggaaatg gatagtgccc cgctggatga cgagggtgaa
     2521 caatcgcata agcgtctggt aaattctcag gtagttcgtg atgatctgta atgatcacgt
     2581 ctacaccagc ttgctgagcg tatgctaccg catcatttcc tgctaccccg ttatcaacag
     2641 tgatgatcaa ctggattcct tcttcgatct tttcttggta taccgattgg tttggtccat
     2701 acccatgctc aaatcgattt ggcaggaata cttctacttc tgcaccaagt aattccagtg
     2761 tttctttcat taccgttgca ctggtgatcc catctgcgtc ataatcaccg taaacgagga
     2821 ttttttctcc actgattaca gcttcttgga ttcggctgat tgctttatcc atatcgtgta
     2881 tcagatacgg atcatgtaat tcttgttcct ttggatgtaa aaatcggttg atatcctttt
     2941 cctcatggta acctctttgc cacagtaact taccgacaaa tggagataat ttcagttcac
     3001 ggatcatttg gagaaaggat tcagaaggct ctgtctcgct taacttccaa tcaaaatttg
     3061 cttgtctcac tttctcactc ctaacttagt tattatagca aaggaaatca gcaaaaaaaa
     3121 gcagaaagaa agaataaaaa cagatcagat ccgctagaca gatgttcagc aggacctgat
     3181 cttttgtacg accatttatg aaatatccct attagtcaaa ataattgaag ctttgtttgg
     3241 gcgattgagt tttttgttct tccggcgctt tcaattgact gatttgtgcg gttttcgctt
     3301 gtaactccgc ctgataagca gcttccaact ccgcacgttc gtttctaaac tcgcgttgct
     3361 gttcttcttt tgcttcttca attttctttt gaagttctgt ttgatattct gacatttcct
     3421 gagtcagctg tttgatttgc tttttttgct gccatagtgt tgccgaagca gtcaaaaata
     3481 caatcagtgc accaatcagc gcagaaccga tgatcactaa gatcaatggc gcagaaaagg
     3541 aagtgaagcc aaaacttaca ggaacatttt tattgttcaa tacagcaaaa agaacaataa
     3601 tcaaaactaa aacaaatcca agaatcacat tgctttgctt tttcaattcc ttcacctact
     3661 ttttgttaaa aattccgctg gctaaataat caccaatcgt tggaaacagc gtataaaatt
     3721 ttgatgcaac ttctaaaata aacggttgat tgatttcccg ttttggatgt ctcatattgc
     3781 ggacgatcat ttttgccaac ttggcaggtt ctaaaacgat ttgtccgact ttttccaaat
     3841 agcttccgct tggatcagcc ttatcgaaga aatttgtctc gattggacct ggattcactg
     3901 tcgtaacagc tacgccaagt ggtttcaatt ctaatcgcaa agcgttggag aagccaagga
     3961 ctgcaaattt cgtggcagaa taaaccgttg attttgcagt tgccattttt ccagccatag
     4021 aggcgatatt aatgatatga ccttgtcttc tttctgccat atcgatcgca aatttttgtg
     4081 tcaaaaccat cattcctaag atgttgactt caaacatatc gtatgctttt ccaaggtcga
     4141 atgtaaggaa gtcttcgaaa atcccaaaac ccgcattgtt taccagaata tcgacgcgcc
     4201 cgacttcttc catcaccttt tcatataatt cgtccacgct ttcaggattg ctgacgtcta
     4261 ccttgaaagc ataagcctct ttgccgctca agcgtctgca ctcgtctctg acaccttcta
     4321 caaatgccat tcttcgtgcg caacttataa cgattgctcc ttgctttgct gcttcataac
     4381 agatttgtgc gcccagaccg cctgaactac ctgttactaa aacaacttta tcttctaaat
     4441 tcatgcctct tcctcctcgc gaaatggaat ctcaatgcta tcaaaatctt tcataatcgt
     4501 cgtgttttca aacacttctt gtgcttcttt ttcaagctct aaagctgctt ttcctaaata
     4561 tctcgcactg atatgagtaa gtagcagccg ttttgcctgc gcttcttttg caacttcagc
     4621 agcttgatga gtcgtggaat ggaaatagtt gtgcgccatt cttgcttcat ctttattaaa
     4681 tgtgctttca tgtaccagaa tatcgctatt ttccgcaagc acaacggaat tatgtgtttt
     4741 tctcgtatcg cctaaaatag tcacgattcg tcctttttta tctggaccta cgaaatcttt
     4801 tccattgatc gtccgcccat cttctagttg gatcgtttca ccttgcttca gtttgccgta
     4861 cagtggtcca gctggaatac ctaattcttt tagacgatcc acctgcaatt ctcctttatg
     4921 atcatgttca accacacgat aaccaaaact gtcgatccca tgatttagtt tttttgtata
     4981 aacagaaaat tgctgatcag taaaaatcgg ggctgtttca tttagctcaa tgaatttcag
     5041 cggataactt aaacgcgttt gcgaaatacc taaagagact tttatgtatt cctctatccc
     5101 ttttggcccg taaatctcta atggcgtatc cccaccttga aatgaccggc tgctgatgag
     5161 cccgggaagt ccaaaaatat gatcgccgtg taaatgtgta atgaaaattt taccgatttt
     5221 tctcggacga atagtcgttc gcaaaatctg catttgcgtg ccttcgccac agtcgaacaa
     5281 ccaaacttca ttgcgctcgt ctaaaagttt caatgctata cttgtcacat ttctatgttt
     5341 tgcaggaaca cctgcacctg ttcctaaaaa ttgtaattcc ataatctacc tgactttctt
     5401 taagttcctc tttaatttta gggtaaaaag aagggataat caaccgtaag tcgagaatgg
     5461 gttcaaatta aaaataacgt tctaaagcga tagcgttttc tttgaaaatt actataaaaa
     5521 cagcagcgaa cccgtttgag atcctctgct gttttttatt aatttgaaga tccagaactt
     5581 tcattgtcgt tggaagtttg cggatgtttg tccttccaag tcttttgtgc agcttctttc
     5641 gcatgatttt cagcttcttt cgcatcatgc acatcttttt cgacatcttc ataatccaag
     5701 cgagtaattt ctccgcctaa ttccatcatt accaattgat tcagtgggcg attgtcctct
     5761 tcatcagcaa tcaagatcag tcctgtagct ccttcaccga ttttatttcc tacaaagtcg
     5821 aacacggtct gggcatcttt tatttctttg gcatcttgtg tcgcaccgat cattcctccg
     5881 gcaaaccatc ctaataaaat ccctagcgga ccacctaata caccaaccaa cattccgatt
     5941 aatccacccg tagaagattt gttattaccg gtaaagtcga taaaatcttc tattttgaat
     6001 tgatgtgtcc cattaggatc atggctgaca actgccatct gttctccttt aatcgaacga
     6061 acagcatgta actttttgat ttctgaaaat gcctgatatg cctggctttc tacttgaaaa
     6121 tttaaaatga ttactcgttt gctcattaaa aacgcccctt tcataccttc ttgttattta
     6181 ttttaccttt aattgaaaaa taagaaaaga aaagcactct ttttttccaa taaaataggg
     6241 ctgtgacaaa agtcgtatca cagctccttt ttccgaataa acggcgttct tgaagctgat
     6301 cacttctgtc acaacctccc ttaaatctga atctatattt tttggtattt gtttttattt
     6361 gcttgcctat tcgacaaatt caaattcaaa ctcaccgata cgtacaaggt cgccatcttt
     6421 cgcaccgcgt gcccgaagag cttcatccac acccatacca cgtaattgac gagcaaaacg
     6481 catcactgtt tcatcatgat cgaaattcgt catttggaat aatttttcga tcttctcacc
     6541 agataagatc cacgttgcat ctgaatcacg atcgatttgg aactcaggac cttctggatt
     6601 gaatccatag tgtacagttt cttcttccag ttcttcttcg tacaatggga attctggcgt
     6661 tacttctaac aaatctgctg tagcattcaa taacgcgtcc aatccttgtc gagtcactcc
     6721 agaaattgga aatactggga tgtcatcagc aaattcatct tctttttcct tgttcagctg
     6781 ttctttgaat ttcactagat tttccggtgc atccggcata tccattttgt ttgccacgat
     6841 gatttgcgga cgctctagca agcgtaagtt ataagtagat aattctttgt tgatggcaag
     6901 atagtcttca taaggatctc gtccttccat cccactcata tcgatcacat gtaaaattac
     6961 tcgtgttctt tcgatatgac gaaggaattg tgtacccagc ccaacacctt gcgaagctcc
     7021 ttcaatcaag cctggcaagt ctgctgcggc aaaacttctg ccatcacttg tagtaaccat
     7081 tcctagatta ggtacgagcg tcgtgaaatg ataagcgccg atttttggac gagcagatga
     7141 aataacggat agtaaagtcg atttcccgac agatggaaaa cctacaagtc caacgtctgc
     7201 caatactttc aattctagtt cgatttttcg ctcttgtcct ggttcaccgt tttcagcaat
     7261 ttccggtgca ggattccgag gagaggcaaa acggatattc cctcgtccac cgcgtccacc
     7321 ttttgccaca actagtgttt gaccattttc aattaaatct cctaaaagag caccagtctc
     7381 cgcatctcgg acagtggttc cttgtggtac tttaacatag gtatcttctg aaccacgacc
     7441 gtgcatccct ttactcatcc cattttcacc tggctgcgct ttgaaatggc gattgaaccg
     7501 aaaatccatc aatgtacgta acccttcatc gacgatcaag atgacatcgc cgccacgacc
     7561 accgtctccg ccagccggtc cgccgtcagg aacgtatttt tcgcgacgaa atgcaaccat
     7621 tccgtctccg cccttgccag ctttcacatc gatcgttact tgatctaaaa acatggacat
     7681 aattaagtcc tcctattatt catttattta tttgactgcc tgaatttcca caataaacaa
     7741 aagtcttact tattttatcg gtgaaatctg attttgtcta tcatttcagc aaaaagattg
     7801 tttaccttct tcttttttta tcatttggta aggtttccaa ccttttttct gctaccaagt
     7861 ataatttttt gacaaaatat tctttgcgta gcagaataac agtgtattaa ttgtattaat
     7921 tgaggatgcc gtttcacagc acccctaata aaggaggaac ttttgatatg acagtaaaag
     7981 taggtattaa cggatttggg cgtattggcc gtctggcttt ccgccgcatc aaagaagtct
     8041 cagatgatat tgaagtagta gcaatcaacg acttaacaag tccaactatg ttagcacaat
     8101 tattgcaatt tgactctact catggtactt atcctggcac agttactgca acagaagact
     8161 caatcgtagt ggatggcgaa gcaactcgtg tttatgcaga acccgacgca agcaaaatcc
     8221 cttgggcaaa agaaaacggt gtagatatcg tactagaatg tactggtttt tatacatctg
     8281 aagaaaaagc aaaagcgcat ttagatgctg gtgtcaaacg agtagttatt tctgccccag
     8341 ctggtgctat gaaaaccatc gtctataacg tcaatgatga tacattagat gaaaacgaca
     8401 aaatcatctc agcaggttca tgtacaacaa actgtttagc acctatggct tatttcttaa
     8461 ataatgaatt tgggatcgaa gttggtacaa tgacaacagt tcatgcctac acttccacac
     8521 aaatgctctt agatggacct gtaaaaggcg gtaatttgcg tgctgctcgt tcagctgctg
     8581 acaatactat cccacattct actggtgctg cgaaagcaat cggcttagtt atccctgagc
     8641 tacaaggaaa attacaagga cacgcacaac gtgttccagt cgttgatggt tcattaactg
     8701 aattggtttc agtattgaaa acaaaagtaa ctgctgatca agtaaacgaa gcaatcaaaa
     8761 aacacacagt tgacaatcct tcattcgggt atgatgaccg tcaaatcgtt tctagcgatg
     8821 tcattggaac aactcaaggt tcgatctttg acccaacgca aacagaagta acaactgctg
     8881 gtgatttcca acttgttaaa actgttgcat ggtatgacaa tgagtatgga tttacttgcc
     8941 aaatgattcg cttactagaa aaattcgcta acttgtaatt tgatagatca atcgataaaa
     9001 gaagcctttg actggatcca gtcaaaggct tctttctttt catcccctac ttttaaactc
     9061 gttcaatgaa catattggct taaaaattgt tggactactt gctgatattt ttcaggatct
     9121 gtcttgtatg cttccgcatg ctcggctcct tttacaacat acttttcttt tggtcccttc
     9181 gttgcacgat agaccttatc taacatttca aatggtacaa atgtatcttc gtctccatgt
     9241 ataaagagca ttgggcgctg gtttttcttc aattgttcca ctgcatttgc ttcaccgaaa
     9301 aagtagccag cacggacttt tgtcactaga ctcgttactt gcataagcgg aaatgctgga
     9361 agactaaaca tatcgtctag ctgataagca agctcatcat gaacggaaga ataaccgcaa
     9421 tcttcaatga ttgctttcac attatctggt agtttttctc cgctagtcat cataactgtt
     9481 gctgctccca tgctgacacc gtatagaacg atttcttgcg attttccatt gttttctagc
     9541 actttgttta tccactgtac atagtcttta cgctctggcc atccaaatcc aatgtaatcc
     9601 ccttcgcttt ttccatgtcc tcttgcatca ggaacaagga cattgtaacc catatcatga
     9661 aacatctttg cgtaattggt catcgtttca gcgtttccca tatagccatg agccacaaga
     9721 gctgtttttt cacttttcgt ttcagcagga agataaatcg ctgataattt cagaccgtct
     9781 tttgaagtga tggtccaatc gcttcggttt tcttttgaac taaaccattt atgtgcatcc
     9841 gtttctttgg atgtctgtgt tgtaccaggt gtatcttcgt ctaaaaagtc tttctcagaa
     9901 ggcacaacag cataattata aaaataattc cctgcaaaca ctaacgcaac aatcagagct
     9961 aaagcgacgc ctaaaaggat tttcatccaa agtttcataa atcatccatc tcatttctct
    10021 tttttcatat aaccttgaat tagtataatc aaagaatctc tactatgcaa tgttcatttt
    10081 tataac
//
LOCUS       DACGDM010000091        10020 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.097, whole genome shotgun sequence.
ACCESSION   DACGDM010000091 DACGDM010000000
VERSION     DACGDM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.097"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(486..710)
                     /locus_tag="IXR05_002323"
     CDS             complement(486..710)
                     /locus_tag="IXR05_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260798.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            910..3678
                     /locus_tag="IXR05_002324"
     CDS             910..3678
                     /locus_tag="IXR05_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4260799.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            3759..4178
                     /locus_tag="IXR05_002325"
     CDS             3759..4178
                     /locus_tag="IXR05_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAQ4260800.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4190..4660
                     /locus_tag="IXR05_002326"
     CDS             4190..4660
                     /locus_tag="IXR05_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4260801.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4677..5456
                     /locus_tag="IXR05_002327"
     CDS             4677..5456
                     /locus_tag="IXR05_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4260802.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5443..6264
                     /locus_tag="IXR05_002328"
     CDS             5443..6264
                     /locus_tag="IXR05_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4260803.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6281..7330
                     /locus_tag="IXR05_002329"
     CDS             6281..7330
                     /locus_tag="IXR05_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4260804.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7343..8347
                     /locus_tag="IXR05_002330"
     CDS             7343..8347
                     /locus_tag="IXR05_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4260805.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            8980..9999
                     /locus_tag="IXR05_002331"
     CDS             8980..9999
                     /locus_tag="IXR05_002331"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4260806.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3362 a         1651 c         2093 g         2914 t
ORIGIN      
        1 taatttgttc ttgcaatctt ttttgctacg taatttttgt aaaaaagtgg gttgagagaa
       61 atctaattga ttttcaaaga aggagtatga aaatgagaaa aatatttatt cgtttattgt
      121 gggtactatc ttagaggaat aaataatagt ggagaaaact atggtttggc gcagattcta
      181 tcaggtttga tggaacgaag acaacctccc gacatcaagt caaaagctac ttgagatttt
      241 gatctgaaaa taaaaaaaga aaacaaggta ggaacatcaa tgtttctacc ttgttttcgt
      301 aatcaatggg aaaaaactaa gagtggtgta cgtaatcaat aaaaaggatg gtgacaacag
      361 tacctcttta ctctctgaaa gcatcataac tcgtttttcc tcattatgcc aataaattgt
      421 tgttatacca catataagga tttgtaatag ctaaaaacag acaggaaagt tgaaatctgt
      481 gaatcttatt ttgtatggaa ggatttatag aacgcaaaaa tcaagataaa gatgaataaa
      541 aatcctgttt cggctatata ttgcgtatct acgccaataa aacgagtttg ttctgtcata
      601 gccatataaa gcaaaggcaa aaatacaact acagcgagat aagatccgat gatttctcga
      661 aaagttttcc aggaagtatg tttcctgttt ttatatttat ccgatttcat tgaatagtca
      721 tagcctcctt attctttcat atgttgaaat tccagtataa aaactggaag gaactgtacg
      781 ttttttagaa taaaaattat aagggataag taggctgctg tctataataa gatatatttt
      841 tcaattcttt attaaagatt ttattgacaa aatgaatccg ttttctatga tggaggaggg
      901 gtgaataagt tgttgaagaa ggaaatttta tgttacttag agaaccagac agcctttttc
      961 gatttagaac atatgaacga ggtctttaca gcacaaaggt tagctgatca ttttggggta
     1021 aaaagaaaca cagtcagtca ttatttgaac cagttaaatg atgagcaact actagtcaaa
     1081 atcaattctc gaccagtgat ttatttccac aaagaagctt ttgaaaaaca attttttaag
     1141 ttacgcacga atttttattt ttctatcgat gatctcaaag aggaacagcc ttttttcgcg
     1201 caaccaaaag acttattctc ttttatgatc ggatacgacg ccagtttgaa agaaagtatc
     1261 gaacaaatca aaacagctct ttactatcca gatggcggat taccactttt gattacaggc
     1321 gaaagtggca caggtaaaag ttatttagtt aatttggtct atcagtattg tctgcttcat
     1381 gatctgctag aagattctgc accattcatc acttttaatt gtgcacaata tgcagataat
     1441 cctgaacttt tgactagcaa tttgtttgga catgttaagg gagcgtacac tggtgcagaa
     1501 gaaaataaaa aaggggcttt tgaagcagca gatggtggga tcttgttttt agacgaggta
     1561 catcgcttaa caccagaagg tcaggaaaaa ctgttcacct atcttgatca aggtgtgatt
     1621 tatcgtatgg gagaacctaa tttgtcacgc cggatcaaaa cacgtctctt ttttgctacg
     1681 actgaagaga ttactagtca tttcttaaca actttcattc gaagaatacc tatccgaatc
     1741 gaactacctg cacttaatca gcgtagtcgt aatgaacggc tagaactgat ttactctttt
     1801 tttctcgaag aacaaagaaa aatggggagc cctttgtcag tcagtggacc agctttgtca
     1861 cttttaacaa gtcagaaatt atccggaaac ataggagagc tgaaaaatat cgtcaaagtt
     1921 tcagcagcaa aagcatatgc tgaacagcgt gaacagcctg aaatccatgt cacgatccat
     1981 catttgcaaa aagaactact tgcgcagcct attactaaaa atacagcaca gcaaggaatc
     2041 tatattacgc aagaccagac cttagagcaa ttaatggaga agcaacagcc cgaacagcag
     2101 cgaatcgtta aaagttttga gcaaatccta attgatttca agaaaaataa ctgtctgcta
     2161 tattcttgcg aaggaaaatt aaagcaagaa gtgattcaat tatttgattt tttgctgttt
     2221 gagaccagta gacaagaaaa acacgagctg ctggtttatt ggacacaatc tatccgagag
     2281 acctttcgac aaatggaaac tgcctatcaa atcaaattcg atggaaacag tgtctatgcc
     2341 ttgagttact atctctatca gcgaagcact atcaaatggt taccggaaga acatgatatt
     2401 atccaactaa tcaaagaatt agaacaacaa gtttctcagt cttatccatc tagttatcac
     2461 tatgtccaac gaattctgga attaagtaag atcaaattag atattgaaga cacaagtatg
     2521 gatcggattt tactgacgat ctatctaaaa aaagcgaaat ggtcaaaaga aaaacgactg
     2581 ccaaaagcga tgattgctgc tcacggttat gcaactgcta gcagtatggc aaatgtagta
     2641 aatcgtttat tacaagagga tctatttgaa tcatttgata tgccactaga tgtcacacca
     2701 cagcagattg cttcagaaat ccttgattat tgcgaaaaca gcgatgtttc aaatggattg
     2761 atcatattag tagacatggg atctctgaaa gaaatccatc agttttttaa aaaacagtta
     2821 tccgtaccgc ttttgatttt gaataatgtg acgacacctt tagcaatcac agtaggggaa
     2881 tgcctgcaaa aaaatgtatc attagaagag atagcagaag agactgttcg acagatccag
     2941 ccagaatggc gactgctcta tccagaggaa aacaaaccca aagcactcat tactacttgc
     3001 ttcactggaa tcggtacggc ggtccactta agtgaactgc tagaaaaaag cttacctacg
     3061 gcttgtcagt tgaaaatcat cccatatgaa tatcagcaat taaaagataa gaaaaacagt
     3121 gacccattat tttccatata cgaagtcgta ggaatgattg gcaccacaga tcctgatatc
     3181 accaatatcg actatctttc attagaagac ctcatctcgg gggaaaagat gtctgtacta
     3241 gctgaatggt tggacactac tatgaatgct tcagagaagg aaatattcaa tcagcgcatc
     3301 attcgtaatt tttcattgga aaaagtactg gattccgtga ctattctaga tacagagaag
     3361 gtgatgggag aaatcgatca ttttatgaga gaattagagg tgcagttgaa tcgaagcatc
     3421 agcaatccca aaaaattagc gttgtatgtc catgtgagct gtctcattga acgattgatc
     3481 cgacaaatgc caatcgaaac ctatcaagga ttagagaaat ggaagcagtg tcaaaaagaa
     3541 gggttatctg ctattaaatc tgcgtttagt gtcattgaag agcattatag tgtcatgatc
     3601 cccaattctg agattgccta tatctatgat attttgagtg aagatacaga gtttctctcg
     3661 atagaagaag aattttgaac ataagcaagt tgttgccact aattttggca tgcaacttgc
     3721 ttttttagta tgtgtaagtg aaaagaggag atgaaaaagt ggatagagaa attatcttag
     3781 cttcccatgg aaaatttgct tcagggatat tagattcatt agagctgatc tatgggaaaa
     3841 atcattctat tactgtattc gattgctata ctgatgagaa ttttgattta gcggaaacag
     3901 taaggcagct ttttatgagg tacaaagata aagaaatcat tgttctgacg gatctttttg
     3961 gcggaagtgt caacaacgaa ttcttacaat atatcaatcg ggatcatgtc tatctcgttg
     4021 ccggattgaa tttgccacta ttgattgagc tagtatctcg gttggacgct gaagtagaga
     4081 caactgtttt gatccagcag gtgctaactg attcaaaaaa aatgatccag ttttgtaacg
     4141 agcggctcaa tcagaaaata gaagaagacg aattttagga ggaagaaaaa tgattgtatt
     4201 gacaagagtc gaccatcggt tattacacgg acaagtagct ttttcatgga cacaaacaat
     4261 aggcgcagac tgtattttga ttgctaatga tgatgtacct acgaatgaga tacgaaagac
     4321 aacgatcaaa ttagccaagc cacaaggagt caaactagtg atcaaatcaa ttgatgactc
     4381 gattgccgcg ttgaaaagcg gggtgacaga taaatataag ttattcatcg tagtggaatc
     4441 gatcgaggat gcatataagc tggcagaagc gtatccagaa atcaaaacca tcaacttagg
     4501 agggatcaag gcaaaacctg gtactcgcag catcggaaaa gcggtaaata ttttaccaga
     4561 agaggaggaa cgcttgaaac gattaattga caaacaaata gaagtagaaa tccgtcaagt
     4621 accagcagat aaaaaagtgg atgtaagaga agttttgtaa gaaaggaaga acctcaatga
     4681 ttgtacaagc agtcttatta ggaattgttg catttgtcgc acaatcagaa tatgcactag
     4741 ggacatcgtt gctttctcgt ccgattgtga cggggctgtt tacaggaatc gtgttaggtg
     4801 atgtaaaaac tgggatcatt atgggcgcaa ctttagagtt agcatttatc ggatcgttct
     4861 cagtaggtgc ttcgattcca cctgatgttg tgaccggtgg gattttaggg acggcttttg
     4921 ctattacagc tggagccggt acagaaaccg cgcttttact aggtttgccg attgctacgt
     4981 tgacattgat attgaaaaat atttacttag ggcttttgat tccaattatg aaccataaag
     5041 cagacaatta tgcagaagaa ggaaattata aaggagtcga gcatatgcac ttgcttgccg
     5101 gtatcggtct ttccttgatg cttggtgttg tggtaatggt ttcttatatg gtgggaagca
     5161 atacgatcgg aaatctatta aatatgattc ctgacttcgt tcaaaagggg ttgtcagtag
     5221 ctacagggtt gattccagct cttggttttg cgatgcttgc tcgtttgctg atcaacaaac
     5281 aagttgcacc atattttttc ttaggttttg ctatagcttc ttacttagag attcctgtga
     5341 ccggagtagc tatttttggt gcgattttag cagttgtggt agtcaatatt atgaatgtcc
     5401 gtcaactacc acttcaaaca actgcagggg aggtagaaga agatgaagaa ttctgagatc
     5461 aaaaacagca aaataacgaa aaaagagcta aatcacgtat tttggcgttc ttttcaaatg
     5521 gagttttctt ggaattatga acgtcagatg aatatggctt atgtttatgc aatgattccg
     5581 attttgaaaa agttatatca gtcgaaagaa gaaatggcag cagctttgaa acggcatcta
     5641 gagtttttta acacgacccc acatatcgtt acactgattt taggaatcac ggctgcaatg
     5701 gaggaagaaa ataaggatga tcctgaattt gatgtgactg cgatcgatag tatcaaaaca
     5761 tctttgatgg gacctcttgc agggttagga gattctttct tttggggaac tttgcgattg
     5821 attgccacag gtgtgggtac ctctttagcc atgcaaggaa atattttagg ccctatcttg
     5881 ttcattttga ttttcaatat tccgcacatt ctgtttcgct atctagcaac aggttgggga
     5941 tatcgcttag gaacgggttt tttgaaaaag atccaggcaa acggtatgat ggaaagtttg
     6001 acattaggcg cgtctattat tggactgatg gtcgttggag caatgactgc cacgatgatc
     6061 accatcaata ttcctttaaa aatcggttca ggagaaaatg ctgtgactgt tcaaagtatt
     6121 tttgatgata tcgttccaaa tatcttatgt cttggagcat ttggcatagt gttttatcta
     6181 ttgaagaaag aagtgaaacc attaacgatc ttgatcggac tagctttctt tggaattttt
     6241 ggttcgtgga tagggatttt ttaaaaaagg agcagagaaa atgtttacga tgcaagatta
     6301 tatctatgaa gaaaaggaag tactaagtac gatcttgaaa aagaatgatt tttcgacaag
     6361 agaacatatg aaaaaaacag tgaatttact gatcttagca acgggttcat cttataacgc
     6421 ttgtttagca gcgaagccag cattggaatc ttatggtgat cttactgtcg atattcaaga
     6481 acctttttat tttttcaatt atggaaaact ttctccttca atcgatactg tgattgctgt
     6541 gtcacaaagc gggaaaagtg cttctactgt tgaagcagta aaaatgatac aaaaacaagg
     6601 gttacctgtt gttgctatca caaatgacgt gcaaagtcca cttgctttag aagctgcaca
     6661 aattattgat ttaggtgccg gggtagaatc agtaggcttc gttacaaaag gctattctgc
     6721 gactgtttta cagttactac tcttagggat aggaattgga ataagtaaaa ataaaatcag
     6781 caaaaaaata gaacaagact acatgcaaca gttgcgcaaa ataatcaacc atttaccagc
     6841 gattattcaa aaaacggaag aattttttga tggatatcaa agtttatttc gtttagcaca
     6901 gcgtttcgtc accattggat atggtccaaa ctggggaaca gctaaagaag cagagacgaa
     6961 attgactgaa acaatccgcg ttccgtcaca aggatttgag ttagaagctt atatgcacgg
     7021 cccatacctg gaggcagatg cttcgcattt gctattcttt attgaagggg aaagtgtaaa
     7081 taaggaacgt tcgcaaaagt tgcaaagata tatgagtcgg tacgttggag agactctcac
     7141 cattaccaca aaaaaagcaa gaaacgagaa aacacttgga ttagcaatag aatgtgatga
     7201 atatctgtct gtattagcgc ttgtcgttcc gtttcaacta ttcgcttata aaaccgcagt
     7261 agctaaaggt attgacttga acaaaaagat ttttgaagac tttgatacag tcttgaaaag
     7321 taaattataa gaggtggaaa tcatgctgaa attcaatgaa gaagaacaaa tcaaagcaat
     7381 aaaaggcgca ctagctttac gtccgcaagt agaagaaatc atcgataaac tttatgcgga
     7441 aaaatttgac gctgtctatt atctaggaat cggtggaacg tatgcttcct cgatgcaagc
     7501 tgtcacttat atgaatggga aaagcaactt gcctgtcttt gtacagcatg ctgcagaata
     7561 ttacactact ggaaacaaaa gattaacaaa agattctatc gttattttgt cctctgttac
     7621 cggtacaact caagaagtag tgaaagcagt agaacaaatc aagaaagtag gagcgacact
     7681 gattggattt atcgataaag cgaacagtaa gttgtctcag ctatgcgatt ttgtggtcac
     7741 ttatccagct cctggaacag aacaaatcaa attttttatg gcagcagatc gattgatgta
     7801 tttgaatgga gaattcgaag cttattcaga atactatgaa cagctcgaac gttatttacc
     7861 aacagggtta gtggaagcag agaaaaaagc agatgcattt ggcttatcat ttgcagaaaa
     7921 acatcgacgt gatagtatgc attattttat tggagcaggg aatcaatggg gagctgttta
     7981 ttcatatgcc atgtgttact gggaagaaca aagctggctt ccatcgaaat ctatccatgc
     8041 tgccgagttt cttcacggga cgttagagat cgtagaagaa acaaccccag tcacattatt
     8101 tttaggcgaa gatgaacaga gagtgttatc tgaacgtgtg gctaaacttt tgccaaaaat
     8161 ttgcagcaat tatacattga tagacacaaa agactatcca gtagaaggta tcagtgaaaa
     8221 atatcgcgga cgtgttttgt ctttcttatt gatgcatgta gtgacacaac gcatcgatgc
     8281 tcatgtggag cagttgaact gccatccatt agagatacgc cgctactatc gtcagtttga
     8341 ttattaggat agactggata aaaagaatat aaaaaataaa gagagcagcg ataactgctc
     8401 cctttatttt tttaaaatat tggcatcaat tacgttataa aacacatttt ttgcattatc
     8461 tacagttcaa cttataatct gtttaatggg acatgtgggt gccaaccatt ttttgttatg
     8521 caatagtact atttagttgt tgcatggatc cgtagtaaaa gtccaagtac aacgagttgc
     8581 gccagtttac atagcgtttt gtatccagaa tgttgactaa aacaaaagtt cctatgtcaa
     8641 ccgtcaacag agacaatctg tccgttgcag gacctgacag atttagaaat gttcaatctg
     8701 tctcttatgt attttaaatc aatactcact aggagaagtt tcctaacctc ctaatagtaa
     8761 tgctggtagt aacattgtca aaactgcttc ctcttaggaa caagcaaagc ataacgagtg
     8821 taaaaataaa atgtagacta ttgtaacata tcattgatta tttcaagtaa aaacgataaa
     8881 agaagtaaac aaacacttaa aaacaatgga aattagtccc aactttaaga aatgtatact
     8941 ataatggaaa ttatcaatta tttatttgga ggaatatcca tgaaacaaaa aatcgcagtt
     9001 cttggtcctg gatcttgggg cactgcttta gcacaaacat tggcagaaaa cgggcatgat
     9061 gtccgtattt ggggaaatgt acctgaacag attgatgaaa tcaataagta tcatacaaat
     9121 cagcattttt tacctgattt gacgatccca gaatcgatta tcggatataa agaattggca
     9181 gaagcagtgg ataacgcaga tgctatttta tttgttgttc caacaaaagc gattcgttca
     9241 gtcgcacagg aacttattgg taaaatgaat actaagccaa tcattataca tgcaagtaaa
     9301 ggactagaac aagatacgca taaacgaatc tcagaagttt tggctgaaga aattccagaa
     9361 gaaaaaagac aggcaattgt tgtattatct ggtcctagcc atgctgagga agtggcagta
     9421 catgatatca caacaattac agctgcaagt attgatcaaa aagcagcagc ctatgtacaa
     9481 aaactgttca tgaatgatta tttcaggatt tatacaaata atgatgtgat tggcgtagaa
     9541 actggtgcag cactgaaaaa tatcattgca attggtgccg gcgctatcca tggattagga
     9601 ttcggagatg atgcaaaagc agcaatcatg actcgaggat tggcagaaat cagccgtctt
     9661 ggtgtcgcga tgggtgccaa tcctctgaca tttatcggtt tgagtggtgt gggggacttg
     9721 atcgttactt gtacaagtgt tcattctcgc aattggcgtg ccggtaactt gttaggacag
     9781 ggacataagc tggaagaagt tctagaaaac atgggaatgg tcgttgaggg tgtggcaacg
     9841 acaaaagcag cagtagagct agctcaacag ctaggtgttg agatgccaat tactcaaaca
     9901 atctataatg ttttgtataa tggagaagat atcaaaaaag cagcaaaaga aatcatgtta
     9961 cgtgacggaa aaatggagaa tgaattttct cttcgttaaa tagatgatca atagttaatc
//
LOCUS       DACGDM010000092         9999 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.098, whole genome shotgun sequence.
ACCESSION   DACGDM010000092 DACGDM010000000
VERSION     DACGDM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.098"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            182..3409
                     /gene="fss3"
                     /locus_tag="IXR05_002332"
     CDS             182..3409
                     /gene="fss3"
                     /locus_tag="IXR05_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAQ4260807.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            3522..3836
                     /locus_tag="IXR05_002333"
     CDS             3522..3836
                     /locus_tag="IXR05_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4260808.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            3849..4223
                     /locus_tag="IXR05_002334"
     CDS             3849..4223
                     /locus_tag="IXR05_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4260809.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            4233..4568
                     /locus_tag="IXR05_002335"
     CDS             4233..4568
                     /locus_tag="IXR05_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAQ4260810.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            4651..5991
                     /locus_tag="IXR05_002336"
     CDS             4651..5991
                     /locus_tag="IXR05_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAQ4260811.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            6069..6743
                     /locus_tag="IXR05_002337"
     CDS             6069..6743
                     /locus_tag="IXR05_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4260812.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            6976..7410
                     /gene="dcm"
                     /locus_tag="IXR05_002338"
     CDS             6976..7410
                     /gene="dcm"
                     /locus_tag="IXR05_002338"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAQ4260813.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            7411..8118
                     /locus_tag="IXR05_002339"
     CDS             7411..8118
                     /locus_tag="IXR05_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAQ4260814.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLLPGKFEQGNRV
                     YEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFPNSTSRRGRLGKQSVHT
                     LLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVNSDSQLYKQAGNSVTVP
                     VIFDIARRLKELDVHGL"
     gene            8108..8398
                     /locus_tag="IXR05_002340"
     CDS             8108..8398
                     /locus_tag="IXR05_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260815.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            8657..9841
                     /locus_tag="IXR05_002341"
     CDS             8657..9841
                     /locus_tag="IXR05_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4260816.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            9856..9975
                     /locus_tag="IXR05_002342"
     CDS             9856..9975
                     /locus_tag="IXR05_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAQ4260817.1"
                     /translation="MGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKGK"
BASE COUNT         3309 a         1683 c         2255 g         2752 t
ORIGIN      
        1 tgttctaaaa tgtgttctaa tttaaaggca gtatatttcg tattttagat taaattttta
       61 ggctcattca ttctcaaatc cattctattc agtcaataaa aattttaaaa agactttata
      121 aacaaagatg ttcaagcgag catcttattt ttttgtgctt aatttgaaag gagaacattt
      181 catgtataaa aaacaaaaaa agaaattatg tgtattaact attttgagtt tggctgttca
      241 agcaattgtt ggagcaattg ctcctacgat tacttttgct gatgaaatta cccatccaca
      301 aacggtaacc gtagaactag atttagcaca tcaatatgct gttgaaggaa cttttagtga
      361 tggtcgtcca atgtcagaag tcactgttcc gcattatgca gtgtacaacg gctttaaaca
      421 agatattttc tgtattgaac caggagtccc gatttacaat gagttcactc ctggctatga
      481 gaaaaacccg ttaccagata tgtccgataa agccaaatta gtttccgttt tatggaaaaa
      541 agtaggtaca gatgcagata ctcatattgt ggcacagaag atgatctggc aagaagttaa
      601 tgggtatacc cttcactcaa taaaacgatc agatggtagt gccgtaaata tcgcagccat
      661 tgaggcaaaa ataaatcaag ccattgacga ttatcagaag aaaccaacct tccataatag
      721 tacggctaaa acagtattag ggcaatcgac tactgtgacg gatacgaata atctgaattt
      781 gtcagagttc gatgaggttg tggaaaatgc cgcaaacatt gattatcgtg tgaatggtaa
      841 tcagttgata atcaccccaa atgccaattc aaaagaaagt ggtgtgctga cgcttaagaa
      901 atctgctggt accggaacac ctgtcgccta taaaaaggct ggccaacaga ctttaatggc
      961 cggggcgatt gataaaccta atacctacac aatcaaaatt gatgtggaaa cggagggttc
     1021 tttaaagatc aaaaaagtcg ataaagaatc gggtgatgtt gtaccaggaa cggttttcca
     1081 tttagacttt ggaaaaactt tacctgcaaa agacgtgact actgacaaag aaggcattgc
     1141 tacattggat gagattcctc atggtacaaa agtaaccatt accgaaaaat cagtaccggc
     1201 gccttatacg attgatacca cccccatgac taccaccatt aaagcaggcg aaaccattta
     1261 cgtgacttca aaaaacgcac gggaaaaagg gcaaatcatt ctggataaaa gcggagttga
     1321 aacagggagt gatctttgga atgacaatta ttccttagct ggtaatacgt ttgccattcg
     1381 caaagacagt ccaaccggtg aaatcgttca agaaatgacc acggatgaaa acggtcatgc
     1441 ggaaacacca aaagagattg ctaatgcgtt ggaattggga acctattatg tgaccgaaac
     1501 taaagctagt catgggttcg tgaatacgtt caaacctgta aaagtcgaat tgaagtatgc
     1561 caatcaaacc gtagcccctg ttaccagtaa cgtaaaaggg caaaatcaag aagtcactgg
     1621 cgaaaccact ttgacgaaag aagacaaaga tactggggat aaagcacaag gtaaggcagt
     1681 ctttgagggt gctgaataca ccttgtttac tgctaaggat ggaaaagctg ttaaatggag
     1741 tgaggctttt aaaccagagt tagcgaaggg aacgaaaggt tctgatgaaa cggtcacttt
     1801 gactttagac gaaaagaacc aagttgccgt taaacattta gctatcaacg agtattattg
     1861 gcaagaaaca aaagcgcccg aaggatatag ccttgatgaa acaaagtatc ctgtatccat
     1921 caaaaaggtg gatgatagcg aaaaaaatgc cgtgattacc cgaaatgtta cggcaaaaga
     1981 acaagtgatt cgctttggct ttgatttctt taaatttgct ggatcagctg cgggcactac
     2041 cgaaactggc ttcaatgatc tgacctttaa agtgtcgcca ttggaaggga ccaatgaaat
     2101 cacaggtgcc gaagatgaag cgaccacagc ttataacgag caattagggt ttgatggtta
     2161 tggcaagttt gaaaatcttc cttatgggga ttatttactt gaagaagtag aagccccaga
     2221 aggttttcaa aagattacgc cattagaaat ccgttctact tttaaggaaa acaaagaaga
     2281 ctttgtgaag agtgagtatg tctttaccat taccgaacaa gaccaaaaac aaccaattaa
     2341 aacggtgacc gttccttacg agaagctgac gaacaaagca ttttctgtta gtttgaaccg
     2401 tttaatgctc tatgatttgc ctgaggaaga agatagttta acttctcttg cgacttggaa
     2461 agacggaaac aaagaattaa cttctctgga ttctaccgag ctagttgata aattgagtta
     2521 caatctacat gaaatcaaag aagactggta tgtggtagcg caagccattg atgtggatgc
     2581 gacaaaagct gcccaagaaa aagatgaaaa agccaaacca gtggtgattg cagaaacaag
     2641 cgcaacgttg gcgaacaaag agaaaacagg aacttggaaa attcagcata aattaaccgc
     2701 cgaacaagtt ttaaataaaa ctattgtctt attcaactat gtgtatgaaa ataaggaagc
     2761 ttttgaagca ggcgataagc cagtagcgaa ggatgttagc ttgaataacc aagcccaaac
     2821 tgtcagttgt acagtggaac accatgtttc tatccaaaca aaggcccacc tagaaaacgg
     2881 ttctcagacc tttactcatg gtgatgtggt ggatatgttt gatgatgtgt cgattactca
     2941 tgatgtactg gatggctcaa aagaagcttt cgaaacaatt ctgtatgctt tattaccgga
     3001 tggtacaaac aaagaaattt ggaaatctgg caagattgat tatgaagtaa atgataaaga
     3061 attcaccaaa actgtgcttg cgaaaaaagt agataccgga aaatatccag aaggaaccaa
     3121 gtttactttt gcggaaatca attacgataa agatgggaat atcaatggaa aacacaatga
     3181 agatttgaaa gaaaaatctc aaaccttaac accaaaagaa gttccaacca tactaagtac
     3241 gccgaaacaa ccggaaacac caactgttcc aagtggctct caagaatcta gtcccacagt
     3301 gaagaccttc cctcaaaccg gggagaaaaa ttccaatgtt ttactgttca ttggttttac
     3361 tttgattttt gcgacggcgg gctattattt ctggaatcgc cggaactaag gtgatgagat
     3421 gatacaagta aatcctaaga accaacgtgc gcgaccgcct cctaaaaaag tagtcgcgct
     3481 atttttgtat ccaaaactaa caatgaaaag aggaaaagaa gatggaattg aaatttgtcg
     3541 tgccagatat ggctgaaacc tttggaaagt taagttatgc cggtgaagga gaaattataa
     3601 cagaaggata tggacggaat actacggtga ttggtcgcag ttatcatttg tattccagta
     3661 agcaacgggc cgatgatatt gaggtggtag tagctgcgga agccggtgaa aaggattttg
     3721 atcaagacca accgctaaaa gccgtgaatc cccatttggt tgccaaaggc tatgagattg
     3781 agaatcgtgg gtttactgat tacgtgttgt atgttgatga tttagtgaaa gcataggagg
     3841 aaaagaagat gagattaaca gaaggtattg tcgtagattc aggtttaaca tttgggaagt
     3901 tgcgtttttc cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga acaattggta
     3961 atgaggtaaa agaacgaacc tataatttaa aatcctctgc acaagggcga atgattcaag
     4021 ttagtatccc agctaatgta cccttacgcg agtttgctta tgatgcagag gtagagttgg
     4081 tcaatccaat cgtggatacc gttgccaatt atgtttttcg agaaggaact accgttaatt
     4141 ggttcattaa ggcggatgat ttagtcttga agcggcagcc gaatcaagga aatcctacga
     4201 accaaaatga aagaaagaaa taggtgaaga ttatggaaat taatgttgaa catattttag
     4261 attgtctcga tcaatatgga aaaggcgagc tgactgagga acaactcgtt aaagcattaa
     4321 cctctgatga aaaaatgttt ctgattatac atcaaggttt acttggagaa aatagcgaca
     4381 gtgaagaaga ctctgatgta ctagactggt taggagaaga agagtctttc tttatagttg
     4441 tcgaagtaaa tgaaaactta tgtcggcagg cagaatccat tttggaagaa attggtgtgg
     4501 agatgccgga tgctattgaa ggctttttaa atcaattggt tgaaacgaaa caactcccct
     4561 cctcgtagca gtaaatgact agcataactt tttgaaattg cctaatgaaa tcctattggg
     4621 ctttttcgat tggaggtgga aaccatcaaa atgtacaaag gacatcgcat acgcgcagga
     4681 gatcagcact tggtttatca ctttgttctt ggctggctac tcgctctgtt catcggttgg
     4741 atgagcgtct tttattttca agagtttaga caatttgata tttctaagct atcactttct
     4801 actattgaaa tcgtttggtc tataaaagat ttagtatgtc tgcttggaag tctcgctttt
     4861 tcaggagcta tgatattgct ttatattcac ttttttcttg atcattggcg aagcttgtgg
     4921 catcgacaaa agctagctcg gatgattcta gagaaccatt ggtatgaagt gaaacaaact
     4981 caaagtgaag gctttttcaa agatttgaat agtagccgaa ccagagagac tatcagttac
     5041 ttccccaaaa tctgttatcg aatgaaagat ggattactgt ctattcgcgt tcaaatttca
     5101 cttgggaaat accaagatca gcttttaaaa ttggaaaaga agttagaaag cggactgtat
     5161 tgtgagttag tagaaaagga actcaaagac tcctatgtgg agtatacttt actgtatgat
     5221 atgatcgcca atcgaattgg gatagacgaa gtagtggcag aaaatgggac tctgcgattg
     5281 atgaaaaatc aagtatgggc ttatgattct ttaccccata tgttaatcgc tggtggcacg
     5341 ggtggaggga agacctattt cctcctcacc attatcgaag cactattgaa gtcagatgca
     5401 gaattgttta tcctcgatcc caaaaatgca gatttagctg atttaggtac ggtgatgcct
     5461 catgtttatt cacaaaagga agaaatttct gcttgtgtgg aagatttcta tgaacgtatg
     5521 atggctcgta gcaaggcaat gaaagaaatg tctaactaca aaacaggaga gaattatgcc
     5581 tatcttggac ttccacccaa ctttttaatc tttgatgaat acgtggctta tatggagatg
     5641 ttaacgacga aagaaagtgc ggtgattttg aataagctca aacaaatcgt gatgttgggt
     5701 cgtcaatctg gtttctttct gattttggct tgccaaaggc cggatgcgaa atatttagga
     5761 gacggaatcc gcgatcaatt caactttcgc gtggctttgg gtcgtatgag tgaactcgga
     5821 tattccatga tgtttgggga ggtcgaaaaa aacttcttta tgaagcacat caaaggtcga
     5881 ggttatgtgg atacaggtgg cagtgtgatt agtgagtttt atacgccact tgtaccaaaa
     5941 gggtatgatt tcttagattc aattagtaaa ttagaaaaga tgaatgattg agtgatcttc
     6001 aatactgact ttatacttca agtaacgtat aatactttta tatagtagga agaaagggga
     6061 taattaatat ggaaagtaat gattcttatt tagagtatgc aaaagcaaat aaggataagt
     6121 ttatttctta tattatcaaa gggaaatccc ccgaagttgg acgagacgca gtttttatgg
     6181 cagggagtcc tggggctgga aaatcagagg ttgccattgg attagctgag aattatgata
     6241 accatgtgat tattgatgcg gattactttc gcacccagtt tcctgattat aatggaaaaa
     6301 actctagtct ctttcaaaaa gcatcttctt ggttggtaga gcaggcattt agatatgtct
     6361 tagatcatgg ctattctttt attctggatg caacttttgc aatattaagt gctgaaaaaa
     6421 atatctcgcg ggcgttgaaa aaacattttc gagtgacgat tttctatgtt tatcaagacc
     6481 ctaaaatcgc ttggaaattt acacaagaac gtgaaattgc agagggacgt catgtgccga
     6541 aaaaggcatt tattaacgct tttttcaaat caagagagaa cattgcaaaa gtaaagagta
     6601 aacatccaga tgtattgctt catatcataa taaaagatta tacgaataat atttccgaag
     6661 ttcattatgc tacggataat ctagaattat ttttaccact agggtatagt aggaaagatt
     6721 tggaggttca attacatgac tgagaaagaa caagtaacga aaattgtaaa gaaatacaat
     6781 aagagcattg cggatttatc ggaaaatgct actgcaaaag agttcaaaac ggtgattaaa
     6841 tatgtagccg atcaggccaa tgaaaaacaa cggaaattag ttggattaaa taaaaaatag
     6901 taggacaaat taataatgta tgagccaaga gcaaaatgtt cttggctttt ttctttgcaa
     6961 tgaatgaggt aatgtatgag atttttagat ttattcgccg gtattggtgg ctttcgttta
     7021 ggtatggaac aggcgagcca tcattgtatc ggtttttgtg aaattgataa atttgctaga
     7081 cgtagttata aagcaattca tgatacaagt aaggaggtgg aaatgcatga catcacaagt
     7141 gtatcagatg agtttattca atccctcgga ccagtggaca tcctttgcgg cggatttccg
     7201 tgccaagctt tttcaattgc gggaaagcgg caaagatttt ccgatactcg aggtacttta
     7261 ttctttgaaa tcgctcggtt caccactctt ctccgaccta agcttttatt ccttgagaac
     7321 gtccgaggat tgctcaatca cgaaggaggg gctacgttcg agacgatcct ccgaacgctg
     7381 gatggattgg ggtatgacgt ggagtggtag gtgcttaact caaaggccta cattccccaa
     7441 agccgggagc ggatattcct tatcggacat tctcgagacg catgtaccga acaagtattt
     7501 cctatcattg gaccgtcttc aacatctgat caaaacatca gaaatttggt aaatatcaat
     7561 ccttccaatc gaggaatggg tggacaagtc tatggttcag atggcgtagc gccaacctta
     7621 acaggtgatg aaggaatcaa aatcgcactg ccagcaaggg atggaatctc tgtagcagga
     7681 ctattaccgg gaaagtttga acaaggtaat cgagtttatg aagttactgg aaccgccccc
     7741 accttgtcaa cgaaacaagg tggtacaaaa atcatgattc gaaaaaatga aacagaatat
     7801 caagaggtga agccagaaga cagtgtgaat ctggcttttc ctaattccac aagtcgccga
     7861 ggtcgtctgg gaaaacagag tgttcatacc ttactaacag gagaccaaca agcgatcgtc
     7921 acggatcagt atcaaattcg gaagctaaca cctagagagt gttggcgact tcagggcttt
     7981 cccgattggg cttttgatcg agattctcaa gtcaattcag atagtcagtt gtataagcaa
     8041 gccggaaact ctgtaacagt tccggtcatt tttgatattg ccagaagatt aaaagagttg
     8101 gatgtacatg gtttatgatg agttgattgg agaaatttat tgggtgattg gaaagattca
     8161 gtcagaccca gaattagaag aacaattgcg acggttaaaa tttgatattc gcaagaatgg
     8221 tgtcaaagtc gctggcgatc catatttaat gaatgaggag acggatgctc gaattgaaat
     8281 aaatcaagta attgcagaat ttgagcggat tgcggaccaa gcaaaagaac cagatattcg
     8341 tcaatacttg ttagaaatga aagcagagtt ggaagtaaat ggtattacag atgagtaacc
     8401 taaaccaaca caactgactg ttaggcgctg accgcggagg attcgcgaag cagaaatcct
     8461 ccgtggtgct gtgcctgttc atggacggcg ttagccgacc atgatgtctc acccccgtat
     8521 ctaacagggg ggtacaaaaa cacaaaaaat aagtaagcaa ccattaagaa tgcttgttgt
     8581 atcaaagata gtaagtaatt tgtataggtg ttaactcatt tgaaaaagtt aacaccttga
     8641 atttggaggt gagaacttgg cacaacggaa tttagattat cggctattaa aagaccgacg
     8701 caacgaatac ggcgtttcac aaaataaatt ggctacggct tgtggactta gtcggccgta
     8761 cttaaatcag atagaaaatg gtggcgtaac cgcatctata aaaaccatga ggaaaatttt
     8821 tgaccaactg gaaagcttta atcccgattt gcctttgacg ttactgtttg actatgtaag
     8881 gattcgcttt cccacaacgg atgcacgaaa aattattcaa gaaattctcc atttgaaatt
     8941 tgagtatatg ctccatgaag attatgcctt ttactcctat caagaacagt atgtcatggg
     9001 tgatattgtg gtgatgttgt ctcatgaaga agataaaggt gtgcttttag aattaaaggg
     9061 gcgaggttgc cgacaatttg aaactttttt actcgctcaa aagcgtagct ggtacgactt
     9121 tttcgaggat tgtctaaagg ccggtggcgt gatgaaacgc ttggacttgg caatcaatga
     9181 tcgagtgggg ctattggata tacctgagct aacgaaaaaa tgtcagaagg aagaatgtat
     9241 ctccttgttt cgtaccttta aaagttatcg ttccggggaa cttttaaagg ctgatgaaaa
     9301 ggacggcatg ggcaatacct tatatatcgg cagtctcaag agtgaggttt atttctgttt
     9361 gtatgaaaaa gactatgaac aatatatcaa gttagggatt ccattagacc aaactgagac
     9421 gaaaaatcgt tttgagattc gactgaaaaa tgaccgtgct tttcatgcga ttcaagattt
     9481 gttaaaaggt cgtagcattg agagcaccac gttttccatt atcaatcgtt acttgcgatt
     9541 tgcggataaa gtagaaggta aaaggcgaac caactggccc ttgaatgaac aatgggggcg
     9601 ttttattgga cggaatcgga aagagattca attaacttcc gagccaaaac cgtataccat
     9661 tgaacgaacc ttgaattggc taggccgaca agtcgcccct acgtggaaaa tggctaagga
     9721 gttggatcga ttgaatcgga caacctatat ccaggatatg gtacagaatg cacgcttatc
     9781 agaccgacat aaaaagattt tggagcaaca aagtatggca attgaaaatt tgattatatg
     9841 aaaagaggaa tcgtcatggg aattgtaaaa gatatttttt tggtatttgg tggcagtatg
     9901 cttggtgtta ctgtgatgtg cttgatgaat gcaagtgcag cagcggatcg agcaatggaa
     9961 aagaaaggaa agtgacaaga tgaatttcgg acaaaattt
//
LOCUS       DACGDM010000093         9993 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.099, whole genome shotgun sequence.
ACCESSION   DACGDM010000093 DACGDM010000000
VERSION     DACGDM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.099"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            112..891
                     /locus_tag="IXR05_002343"
     CDS             112..891
                     /locus_tag="IXR05_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260818.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
     gene            937..1881
                     /locus_tag="IXR05_002344"
     CDS             937..1881
                     /locus_tag="IXR05_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4260819.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1897..2676
                     /locus_tag="IXR05_002345"
     CDS             1897..2676
                     /locus_tag="IXR05_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAQ4260820.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            2688..3386
                     /locus_tag="IXR05_002346"
     CDS             2688..3386
                     /locus_tag="IXR05_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAQ4260821.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3414..4178
                     /locus_tag="IXR05_002347"
     CDS             3414..4178
                     /locus_tag="IXR05_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAQ4260822.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            4222..5673
                     /locus_tag="IXR05_002348"
     CDS             4222..5673
                     /locus_tag="IXR05_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4260823.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            5705..6841
                     /locus_tag="IXR05_002349"
     CDS             5705..6841
                     /locus_tag="IXR05_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4260824.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDVVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            6841..7947
                     /locus_tag="IXR05_002350"
     CDS             6841..7947
                     /locus_tag="IXR05_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAQ4260825.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFH
                     AIKNNSVLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLF
                     EGVPLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRD
                     SERSILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            7953..8975
                     /locus_tag="IXR05_002351"
     CDS             7953..8975
                     /locus_tag="IXR05_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4260826.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            8997..>9993
                     /locus_tag="IXR05_002352"
     CDS             8997..>9993
                     /locus_tag="IXR05_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4260827.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLL"
BASE COUNT         3644 a         1422 c         2071 g         2856 t
ORIGIN      
        1 atttctgtga atatattagt ttaattatgt ttttttaaat aaaaagctgt catttttatg
       61 taagtgaatt atatcttaat ttatctatca tcaatactta ggagtgaatc tatggaaaag
      121 ccattcgtca agtcattgac tgctgtggcg gtaggtgcag gtgctattgc gatctgtttg
      181 tttggatacc atatcaataa tcagcggcaa catcagcaac ggatcaatta tgcagaatct
      241 gccatcacca atcaaaaaga caccttgact tctttatcaa aagaagtaga caagctgtat
      301 agtacaaaag aaaaaatttt tctaaaccct gaaataacag aagaaacaat cacaagtttg
      361 tcaaataagc tatcctctgt caaactttca gcagatgatt acgacatcaa agaatcagaa
      421 ttgcctaaag aagctgttgc aatccaagat gagaagaaag caatcgtgac acagttagat
      481 agtgcagaat caaaactgaa gatccagaca gctgtcaacg atttatttac taaaaatgta
      541 tcaaactggc agcaagctgt agacgatgtc atcatcaaag aaaaggtgac aagtgcagat
      601 gtcgctcgtg tacgtgaaaa tatgagcttt tttaaagata gtccttggaa aacggttgtt
      661 atgcaatatc taggattcgc tgatattcag atcgcgcaag tcacgcaact agatcagtta
      721 ttcgatacga tgttaaagga tggtcaagtg actgccaccg ctacttacga tcaatatttg
      781 acggtgctca gtcaaataga gcagatccgg aatgaaaaaa taagcgcagc atacgcaaca
      841 aaagcacaaa ctgttgctga gcaaatgggc tatagcaata taagctattg acagttaaaa
      901 cgttgattca agcaaggtta gcaaacggag gaaactatgg caagacgaag aagaaaatca
      961 agagggaaaa aaatatttct gattatttta gcagttctta tcgtattagt attagcaatt
     1021 gtaggagtag gagcaaaatt atatctggat ctctcacatt ctattgagaa aacttacgaa
     1081 tcagtggaac gaacccaagg agaacgaacg aaaccagttg atctggacaa acaagaatct
     1141 ttctctgttc tattgatggg gattgatact ggagatttag gtcgggtcga tcaaggaaga
     1201 tcagatacga tgatggttgc cacagtcagt cctgaagaca aacagacaac gatcgtcagc
     1261 attcctcgtg atacgtatgt cgacatcgta ggtcgtgaca caaaagacaa gatcaaccac
     1321 gcttacgcat tcggcggagc tgccatggcg atggataccg tacaaaaata tgtagacatc
     1381 ccaatcgatc actatgtctc tatcaatatg aaagggctaa aggaactcgt tgatgcagtt
     1441 ggtggtatcg aagtcaataa tgacctcact ttctcacaag atggctatga ctttccaatc
     1501 ggtaaaatta cattgaacgg ggatcaggca ttatcttatt ctcgtatgcg ttatgaagac
     1561 ccaaatggtg attacggtag acaagggcgc caaagaaaga tcgtagaagg cgtagcgaaa
     1621 aaagtattga gtctaaacgg tgtcagcaac tatcaatccg ttttgaatgc tctagagtcg
     1681 aatatgaaaa cagacatgaa ctttgatgaa atgaaaaaaa ttgctttaga ttatcgggag
     1741 gcatttggta cgattaagca agatcagctg caaggagaag gcttcatgca agataatatc
     1801 tcctatcaaa aagtcagtga tcaagaactt gatcgtgtga aaaaagaatt aaaagatcaa
     1861 atgaatctag agaataaata ggaaagtgga gaaaaaatgg aagagacaat cagcttgaaa
     1921 gaaatttttg aaacattacg caaacacttg gtaataatca tcatctcaat gtttgctggc
     1981 ttggccatct caggaatcgt aacatttttc atcttgacac caaaatacag ttcacaagca
     2041 caattgatcg tgacactgcc acaatcagac actgcaaatg tcaatgatgt caatacgaac
     2101 ctgcaaatga tcaatacgta taaagatatg atcgtcagtg atttagtgct caatgaagtc
     2161 aaagatcgtt tagaaacaga agacaatgtg aaaatgactg ctgaacaaat caaagatgcc
     2221 atctcagtta atcaggcaga aaattcacaa atgttctcga ttcaggcaat aagtacgaat
     2281 gcagtggctg ctcaacagat cgctaacaca acttcacaag ttttccaaga gaacgcaaaa
     2341 gatgtgatga atgttgataa aatctcgatc atttcaggtg cagttgccaa tacgacacct
     2401 gtttcgccaa ataataaatt gaatttaatg actggcttaa tgttaggaat gatggtaggt
     2461 gtaggtctgg cattcttatt ggaattactc gatcggacag tgaaagatga aaaatatgtg
     2521 acagatacat taggattccc aatcttagga acagttccag aaatgtcagc gaaagaattg
     2581 aatgctggta tccgtaaaaa aggaccagct cagacacaac caaaagctac aaacgataaa
     2641 acagcgccat cacgcagaag ccgctcaaga gtctaggagg aaagaaaatg gcacgaacac
     2701 agaaacaaaa agcagcccaa actcatgcag tcagtttggt cacactcacc aatccctctt
     2761 caccaatcgc tgaacaatat cgtacgattc ggacgaatat ccagtttgcc tccgcagctg
     2821 gtcagcaaat caaaacgatt gttgtgactt catcaggacc tggagaaggg aaatcgacca
     2881 ctgcagcaaa cattgccgtt gtttttgcca aatctggtca acgggtgctg ctagtcgatg
     2941 cagacttacg taagcccgtc atctataaaa cgttcaagtt gaacaacgca agcggattaa
     3001 gtactgttct tagttcatca ggaagtgtag cagatgagat ccaacgaaca ccagtcgaca
     3061 atttgtcgat tctgccaagt ggacctaaac caccaaatcc atcagaacta ctaagttcgc
     3121 caagaatgga tcagatttta gcagaagcaa gacaactatt tgatgtagtg atcttcgaca
     3181 tgccgccagt cgttgccgta acagatgcac agatcatgtc ttcaaaaacg gatggcacct
     3241 tattggtcgt acgggaaaat acgtcacgaa aagaatcatt gactaaagca aaagaactgt
     3301 tagatatggt acaagcacga gtcttaggtg tcgtatacaa cggagcagaa cacagcaaag
     3361 atgctggtta ttactacgga aattaaggaa taagaagaga ggagacaaga gaaatgatcg
     3421 atctacattg ccatatccta ccaggaatcg atgacggggc agaaaactta gaagcaagta
     3481 ttgcaatggc tgaaaaagcg attcagcaag gcattacgca tattttatgc acaccacacc
     3541 acaataatgg aaaatacagc aatgaaaaat cacaagtcat ttctctagtc gcttcgttac
     3601 aagccgaatt agagaaaaga cagttgcctt tgacgttatt ggaaggacaa gaagtacgta
     3661 ttaccggaac gctcatcgaa gacatccacc gagatgaaat tttatttaca gatttagatg
     3721 atacatatct tctgatcgaa tttccgacac tggaagtgcc gttatatgca gaacggcttt
     3781 tttttgagtt gttagaacta ggaaagatac cagtgatcgt ccatccagaa cgcaacgcgc
     3841 attttcgaga agacccaaat catttgcttc cgttcctaga tatgggatgt ttggcccaac
     3901 ttactgcgcc aagttatgtt ggtgtatttg gcaaagatat ccagaaaaca gccaaaacaa
     3961 tggtcaaaca taatctcgtg cagatggctg cttctgatgc acacggggtc tctaagcgca
     4021 ccttttactt aaaagagtgc tatgagcaga ttgccaagga gtttggtaag gaaaaagtag
     4081 tacagatgaa acaagtcgca aaggatctga tcaacgggga tgagatcaat tatccaatct
     4141 atgaagaggt aaaaaagaag aagtttggtt tattttagtt ctttattcgt agataaaaag
     4201 gaaatgagga gagagtgaga gatgtataga aaaaactcaa gtggttggtc taaacatatt
     4261 gattttattt tattagactt attttgtgtc cagcttgctt tttatatatc atatgtaatg
     4321 cgacagggtg actggaatcc gtatgtgatt cctatttatc gccacatggc aatttttata
     4381 gaacttgaga atcttacgat tatattttta tttgaggcat ataaaaatgt tttaaaaaga
     4441 ggatattata aagaggctgt agcttctata aagcaatctt ttatgctgtt acttgtgtgc
     4501 agtttatacc ttattacaat gcaggatgga aatgattatt ccagagtttc tttatttata
     4561 atgggggtgg tgtatggatt attaacatat ataattcgta tactttggaa agggttgttg
     4621 catcaccgca tgaaaaacgg tgaagatgta tcgttagtta ttgtaacatc tcaaaagatt
     4681 gcaaaaaatg tagttcgtaa tcttaaagag aagaattatg gcatgtataa acttagtggt
     4741 gtgattgtag tagacagaga tatgtatgga actaccatcg gaggtgtccc agtagttgca
     4801 aatgctgata atgcagcgga atatctttta cagaattggg tagatgaagt attcatcaat
     4861 gttgacgaaa gtgttccata tcccaaagaa ttaatcgcca gatgttcgga aatgggactt
     4921 gctgtacata tgaatcttac aaaagtgtct gatagtacac gtggaaaaca atttattggc
     4981 cgagttggtg attatactgt tattacatct agtattaatg ttatgacgat gaggcaagca
     5041 tttataaaga gaacgattga cattcttgct ggaattattg gatgtattgc aacaggtgtt
     5101 atttttatct tcgtagcacc agttatttac atcaaatcac cagggccgat tttctttgca
     5161 caagaacgta ttggtcaaaa tggtaagaca tttaagatgt ataagttccg tagtatgtat
     5221 atggatgcag aagaacgcaa agcagagttg atgaaagaaa ataagatgag taataatctc
     5281 atgtttaaga tggattttga cccaagaatc attggcaata aaatacttcc tgatggaaca
     5341 aagaagacag gaattggaca atttattcga tctacatcat tggatgagtt tccacaattt
     5401 tataatgtcc taatgggaaa aatgagcctg gtggggttta gaccttgctt gaagtcagaa
     5461 tatgagaagt atgattttca tcatcgtgcg agaattgcga tgaaacctgg gattactgga
     5521 atgtggcagg tgagtggtag aagtgatatc acagacttcg aagaggttgt aaaacttgat
     5581 gcagaatata tcaggaattg gagtatggga ttagatttta gaattttgtt taggacagtc
     5641 aaaactgtgc ttcatagaaa cggttccatg taagataaag atactataga aggagtaaaa
     5701 cgtgatggca agaaaaaaat taaaaatctg tatgctaggt cataaaagaa ttccatcaag
     5761 agaaggtgga attgagatag tggtagaaga attggcaacg cgaatggttg cacttgggca
     5821 tgaagtgact tgctataatc gaagtggtca tcatgttagc ggaaaggaat ttgaccagca
     5881 taaaaataaa gaatataaag gtgtaaaatt aaagactatt tttacattaa atataaaagg
     5941 aattgcagca atgagttctt cagtatttgg tggaattaga gcagcattcg gaaaatatga
     6001 tgttgttcat tttcatgcag aaggaccatg tgctatgttg tggttgccaa aactttttgg
     6061 gaaaagatgt gttgcaacaa ttcatggtct agatcatcaa agagaaaaat ggaacaagct
     6121 tgctagtaca tacatcatgt taggggaaaa gtgtgctgta aaatttgcag atgaaataat
     6181 tgtacttagt gaaagcgtcc aaaattattt tgaagatata tatggaagaa aaacaaggtt
     6241 tataccaaat ggcgttaaaa aaattgaaat aaaatcagca ggattgatta cagaaaagta
     6301 tggattaaca aaagattctt atattttgtt tttggggcga ttggttcccg aaaaaggaat
     6361 tcggtatcta attgaggcat ttaaagatgt tcagacagat aaaaaactta taatagccgg
     6421 aggaagctct gatacagatg aatttgcaaa tgaactaaag gaattagcaa aaggtgatga
     6481 gcgaattata tttactggat ttgtacaagg acaggaatta gaagaattat atagtaatgc
     6541 gtatatctat acacttccaa gtgatttaga aggaatgcca ttaagtttgt tagaagcaat
     6601 gagttatggg aactgttgta tagtttcaaa tatctcagag tgtacggaag tagtagaaga
     6661 caaggctatg atttttaaga aatcggatgt aagtgattta aagataagat tagaagaggc
     6721 atgcaatcaa tcggaaatgg ttaaagtttt gaagaatcaa gctactgagt ttatttgtag
     6781 taaatataat tgggataaaa tcgtacaaga aacattaaat ttgtataggg gaaatatata
     6841 atgattcgaa tattacagtg tgtgaatgat atgcatcgtg cagggttgga gacgatgcta
     6901 atgaactatt ataggaatat agatcgaact aaaattcagt ttgatttttt gacacatcgt
     6961 ccatataaaa gtgattatga tgaggaaata ataagtcttg gaggaaaggt ctattatgca
     7021 ccgagacttt atccacaaaa ttatcctaaa tattttaaat ggatggaaca attttttaag
     7081 gatcatccag aatatgagat tgttcattct catattgatg cgatgagtta tttaccttta
     7141 aaagctgcaa aaaaagctgg gattccgata cggatagcac atagccataa tacatcgata
     7201 gatagagatt ttaaatatct tttaaagcaa tattatcgat gtaagttaac gtctgttttg
     7261 acacatgaat tttcatgtgg aaaagtagca ggtgattttt tgtttcgaaa tgataaattc
     7321 actttgattc caaatgcagt ggatgctaaa aaattttatt atgatgaaag tattagaaat
     7381 gatgtacgaa tgaaattagg aatttcaagt cagacgtttg taatgggaca tattggaaga
     7441 atttcatatt ctaaaaatca tcgttttttg attgaaattt ttaaagaatt tcacgctatt
     7501 aagaataatt ccgtattatt aattattgga actggtgata tggaagaaga aataaaaaat
     7561 tatgcaaaga aaagtggcat agatgatgat attaaatttt taggaaatag aaatgatata
     7621 gaaaaatttt atcaagcatt tgacgtatta atgttgccat cattatttga aggggttccg
     7681 ttagtgggta ttgaagctca atttgcagat ttaccgtgtt tcttttcgga gaaagttcct
     7741 acagaagttg ctttcagtga taagaccaat ttcataagtt taaatcaatc ggcaaaagaa
     7801 tgggcgagag agattgcaaa tgtagatatc tctcatcgag attcagaacg ttcgatttta
     7861 ataaaggcag attataatat tcaaacagca tacaaaatct tagaatcaaa atattatgag
     7921 ttatttgaat taatacaaag aggttaaaga atatgacaca gaaacattca agtataaaaa
     7981 gaattataca tcgcatatcc gaagaattga atgcaacaag acgaattgca aagataacat
     8041 cttggaagga agcatttgcc acgttacaag ctaaaattga tattcaagtc atgaatcgta
     8101 atggatataa tgaaagtaaa aaacagaagg aacatttatt aaaaaaacat gaggtaatgc
     8161 tgaagtatta tgaaaagact ttttcagatt ttttgaaaac atatgattat agtcaaaatc
     8221 aaataattaa tcaatcaaaa tcaccatatt ctaactgcat ttgggtttgt tggtggcagg
     8281 gattggatca atcgccggaa attgtaaaag cttgtgtaaa atcaataaaa cgaaatgcag
     8341 ggaaacatac tgttataatt ttaacagaag ataattatag acaatatgtt gatataccaa
     8401 aatgggtgga agaaaagaaa aacaaaggaa tcattacgag aacaaattat tctgatttat
     8461 taagattatc tttgctagca aaacatggag gtttgtggtt agacgccaca ttttattgta
     8521 caaaaccaat accagatgag tattttgata tcgatatttg gtctattagg aggcctgatt
     8581 atgctcacgc atccgtagca tcaggatatt ttgcgggtta ttcattagca tgtaatcaag
     8641 agtctagatg gatgtttgct ataattagag actttttttt aaattattgg aaaaataatg
     8701 atatgatggt ggattatttg atgatagatt atatgattgt tttagcacag agaataaatc
     8761 atgaaatagc acagacattt gataaaatac ctagtaacaa tccattatgt gacgaattga
     8821 ttaaaaattt aaataatata tatgatgaaa aagtatggaa cttattaaag aaagatactt
     8881 tactgtttaa gttgacatgg aaacaatctt ttaaaaagca aaaagatgat aaagttactt
     8941 tttatgggat gttggtagaa aacaaattat tataaatatt agaggtataa aaagttatga
     9001 aacacaaggt aagtgtgata gtaccaattt acaatgttga aaaatattta agaaaatgtg
     9061 tggatagttt attgagtcag acattaaaag agatagaaat cgtattagtt gatgatggtt
     9121 cgccagatgc ttcgggggaa atagcagatg agtatcaaaa aaaatattct aatgtaaaaa
     9181 caatacatag agaaaatggg gggttaggac cggcaagaaa tacaggaatt gagaatgcga
     9241 caggagaata tgtggctttt cttgattcag atgattgggt agaaagtgat atgtatgaaa
     9301 aattatactt agttgcgtcc aaagaaaatg ctgatatagt agttagtgga cattgtgatt
     9361 ttgcgaatga caaagctatg gtgaaaaagc aacatccttt gagtgggaat gtatatgata
     9421 cgcctaatag tattaaaaat gtacgaaaaa atttatttgg acatagtcca aaagatcaag
     9481 aagtagaggc cttcccgatg tcagtatgta tgtctttgta taataaaaat ctgctagata
     9541 aatatagact aagatttgaa aaaattttat ctgaagatac aatttttaac ttgaatgcat
     9601 atgatgtcgc aaataaaatt gcttttacag aatatacaga ttattgttat agaaaagaag
     9661 aacaagagtc tattacaaaa agtttatctc caaataagca gacggaattt aaagaatttt
     9721 taataactct aaaagctata gcatcgaaag aagatttaga atgtcaaatc agagcaaaac
     9781 gtatggcaat tgattattgt aggctttatg tgggcttagt tgatgatgca aatttgggaa
     9841 ttaaagagaa aagaaagtat ataaaaaaat ttattgaaga tgagggatta attcaatgtt
     9901 ggaagggata tcctacaaat acgctaccat ttcaacaaaa attttttcat aaaatgcttg
     9961 aatgtaagtg ttatacaata ttgttgttgt taa
//
LOCUS       DACGDM010000094         9692 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.100, whole genome shotgun sequence.
ACCESSION   DACGDM010000094 DACGDM010000000
VERSION     DACGDM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.100"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(306..728)
                     /locus_tag="IXR05_002353"
     CDS             complement(306..728)
                     /locus_tag="IXR05_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4260828.1"
                     /translation="MRNKKVIVRILIVSFLLFGCFKLIKTNEESNGKLINSNLEEVLE
                     LQKTNQSFFVYLARNDCKKCQEVESFLERYDKKFSRNVYRIETRKEPRQEELQTFLQR
                     YHVKSVPSFLVIHDRNVKKIERKTFFFEKTLNQFLPNF"
     gene            complement(718..2892)
                     /locus_tag="IXR05_002354"
     CDS             complement(718..2892)
                     /locus_tag="IXR05_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 family protein"
                     /protein_id="HAQ4260829.1"
                     /translation="MMNAPKRPTHFEQMFSVDRKRKQEKETPKSRFQQLYFIVTLLGV
                     CLYPFFIVGSIPLAIVFMIDKKETRAHIYDFEYESFLKRRSSLFFIFALGFTLLNLFC
                     FIFVLPRGYLSCYLLFPLNLFSHALQFNGQTIFALLLGGTGAGSCLIAYASFIEKRKV
                     VSKKERQTALLNSKEYKERRKNKFQESQKYTAEYQQAYQVAIVIKDVALRNKQLASLA
                     KVILLGTDEYGLPYVMNFSELNQHVIIPATTGSGKTTVIQLLAEHACKFRIPVILVDG
                     KGAGETLQALKEVAEAYNRPIEVFVDGGDLRYNPVKNGNDIAIRDKLTNLAETESVYY
                     STAAKALLQVTIQLLDEFQKSHKIERNLVWLQHYLLPRNVLHLFADRIQLKNPDLFKE
                     KVVVEKKKTTKKKTKKNEAMDKTERDFADVEQLSEERIVEHDRKTVDLETYYLLLKEN
                     ISLMTEIEQTLFKRLFVRYEHKKNPFYLYATSENLQTNINMLLDSELGELFDTSGGKR
                     ELDIQEVVKEGKIVYISLNGLIYSEFIRTLAQMLVGDINFFASEVYKQAGETANRSKV
                     LVIFDEPASYLNDNLIDLVNKGRGAGVHAAYAPQTLADIDRIDPVLRKQLIGNVNTFF
                     IGKTNDPTEIDYWADLMGTEEDIELTEMTTQEAGYSDMGKVDWTGERGTKRDVDRFKF
                     NPNRIRALRTGEFVVYRTAEDVQEPPRVVYIRKPNLEKQYAK"
     gene            complement(2908..5250)
                     /locus_tag="IXR05_002355"
     CDS             complement(2908..5250)
                     /locus_tag="IXR05_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260830.1"
                     /translation="MRKKSLKWWTLLLLGGLFFCLQGATVSADQMNDGAGVTETDRSE
                     GENANDKVEVKEVTTDVDQLYKNYKKNSFELMTNDYESMNLKKKLSYNVAGVMKNFVW
                     SGVKMLGEFNASMVEFLFELDIISAIREPIQNLTQKIADNMLSIAGTIGISFSAIMMA
                     IKYAGEARMKQALRVFLMTILIFTGLSVLKDSGTNKNLFDVLFSLDSTVETAFVKVNP
                     VLTPEEETNYETKETEEVTADKKVETAGKLMAARVFYSNVYEPYLLLNYGTTNVDTIR
                     EKKVKYAGKEYDRINLLLDNDLGTKIGEKIHDKVTEYEADTLKNKNIQYYNSWKNTAF
                     ALFYFVVNLIQTVVYFVLSMFRLIIGTMQLLLVPMLPFLLFLGLFLVTMNVFGNYAKV
                     FGILTFLKGMTGFACILFSSFLSYGFQLSSTQDDPWEKILLIIVYLFAPLGIYLFRGF
                     LGSLFTGRMGVRGALAFAGNPFGAEAKLRREAKQRLKERKEARKAQKQKEKENARKRQ
                     ERQRKRGGGSDVRMPQTAKQATRSAFRRESAQQPRHKAPNRMERMAQKARDLHDQAKQ
                     AEEQSQERMQRTAMEKQARKTADLLQRELQGNPSLRERSRKGASRSPYRNQGSAMVVS
                     LANPKQKHKSYGQKHTPRTELNDRKRRQGQTSRRRKEALTPVTKTSSMKTRTVAGQKH
                     AVQKPLRKGNVPRATGSTTPKSVRRPEGVREHMSAVNRVTAQTKAPSTVSKAYSTMKQ
                     TKSPKQAPKTRSEFRATQAKMKRKREKQPIYRREMKQRKR"
     gene            complement(5272..7815)
                     /locus_tag="IXR05_002356"
     CDS             complement(5272..7815)
                     /locus_tag="IXR05_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="HAQ4260831.1"
                     /translation="MAFLFLLVVFIIGIWQFKKKKTKLPRLEFPIDAIIRNFVLTKND
                     DVWVGYQLSSQVFPLNDIDFFKNYLQDGEGILGHDEYDYHFINIPRQFNLDTHIEETI
                     RDLVKGECADLGKVYFEQAGKILKDEVQLNEYRTYLFVRFTTEMKVSDPIEYFQLLKH
                     VFKKFIYRITGQRVPISSVLPTYETLEKELYTELSNYKPIERLSAQEIGQIYYYFFHR
                     SEEKLPERQLTPMEICEGVISNEAGYIAIEQLNQTHYSTFLSQTDAPLAMYGSSFIQN
                     LQDSLSFPIDTHIRLRFEHSKSDERKINKMAGRIYEQEKEYETVDGILDSDDVLNFGT
                     ERLMDVKDKLKRKEKRLCYSTVTLVVSASSKEELEERVKDIEFAIESTDFKFYRSVAD
                     QLTLFNQCLIGSTQRFRSYEQVATTGFVADYGLDLKKEVGNKKGFPLGRIVIAKKFKS
                     AKEALALSSKLVWYYPNLTKKSIEGAEHTNGNTLIIGPPGKGKSVLVKYIFLWLMFLG
                     QKILYIDPKNETQKFFLKALEKFGHIPEFVAMYERINFISLSSDESCRGMLDPLLFLP
                     KEEAIQTAKNVLGMLGEVDTNRETASHKKTVIQDAIDVVYTMPGKHSLSQVIEEIRKS
                     DKELAKLILGHSVGLGKILIGNEHSTPIRFDSQINVLGTQGIRIPTQKEIDSGRLNSE
                     QLAGMAIMEVIMKFTYIFSTNKEEDAAIIYDEAKGYEDTAQGSYLIDDSLRKGRANNT
                     DIYLVVQAFKDYDQEDKKELISYKFAFRPKQKEAREKLLSFFDMEVNSANLEMMEQLQ
                     TGTCLFQDHLGRNQPIAIDVLFDSWLLAVSSTENQDEKIQAMLENEKQR"
     gene            complement(7825..8223)
                     /locus_tag="IXR05_002357"
     CDS             complement(7825..8223)
                     /locus_tag="IXR05_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4260832.1"
                     /translation="MEYNYTKEFKHPHKIYGIKGQKIPWISNGIRMEQLVIGGVFLFI
                     LLILFLIAYVNQISFLQTLFRKSWLIMIFGIGVLVWTLFSMKWDNKHFFEYLIGRTSY
                     YQKRKQRFEHEMYVPFFHEKVTYSLHKWKE"
     gene            complement(8304..8588)
                     /locus_tag="IXR05_002358"
     CDS             complement(8304..8588)
                     /locus_tag="IXR05_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260833.1"
                     /translation="MKLFDLKSLFDDVSGQVIWLLAIVAIVLMVGAYATQGFARAAFA
                     IIGVFILIMLVLLLSNAVDIGEWLKNIIFIKDSEENVGVTQMIVPWIQLS"
     gene            complement(8612..9610)
                     /locus_tag="IXR05_002359"
     CDS             complement(8612..9610)
                     /locus_tag="IXR05_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4260834.1"
                     /translation="MSNAKFNPQAFQTKPPKQQKEKKQKKRFLFQKKKTEPSDRMIQF
                     SQKSAMSVFSGAFFCLFLLMGVVLLLNFGRVDTLTRLAVKKQVNPETLLTEVNQTLSS
                     TEQLKYEGQHFIERLFTYSPEKRNEWEASVNHYLAQGLEASDLGFVTTATNRVAKDVR
                     FIKLEEIDLTQAMYRLFYEVTFTEGEHWKSSQLSFPVSYQNNVLKVLDGVQFLNLSES
                     KNTNSVNYQENRFYSSGQAVTESEEIKLEAFVKRFFELYVKNDEKLALISNEKGLEGG
                     ELINVQLDHAVKNKEGNYFLQGKYRFYFEKGNEFQSNFSMEVKTSGDSYFVTTLNE"
BASE COUNT         2792 a         2050 c         1495 g         3355 t
ORIGIN      
        1 tattacatat aacctttaaa taatctctaa ataaccctca aataatcctt actaatactg
       61 aaacgtaaaa aaaataaacg gatttcaaac aaaatacgtt tattttttct attgatttta
      121 gctcaaaatc gattcaattc gagtgaaatt tgcttcaatt ttcaattggt ttttgttcaa
      181 attttgaaac atttttgctc aaaaaatgag tgaatttgtt tcaaaagaaa aacaaatacg
      241 atcgaaaaaa atttgaactc ataacaattt tttgtttttt tcaacgtatt ctctttcaat
      301 tttcactaaa aattaggaag aaattgattc aatgtctttt caaaaaagaa tgtttttctc
      361 tcaatttttt tgacgtttct atcatgaatc acgagaaaac ttgggacact tttaacatgg
      421 taacgttgta aaaaagtttg aagttcttct tgtcttggtt cttttcttgt ttcaattcga
      481 tatacattcc tagagaattt tttgtcgtat ctttccaaga aagattcaac ttcttggcat
      541 tttttacaat catttcttgc tagatacaca aaaaatgatt gattcgtttt ttgaagttct
      601 agtacttctt ctaaattact attgattagt tttccatttg attcttcgtt agtttttatc
      661 agtttaaaac aaccaaataa gaggaaacta acaataagta tcctaacaat aactttctta
      721 tttcgcatat tgtttctcca aatttggttt ccgaatatag acgactcgcg gtggttcctg
      781 gacgtcttca gctgttcgat acaccacaaa ttcgcctgtt ctcaatgctc gaatgcgatt
      841 cggattgaat ttaaagcggt ctacgtctcg tttcgtgcct ctttctcctg tccaatcaac
      901 ctttcccata tcagaataac ctgcttcttg tgtcgtcatt tccgttaatt caatgtcttc
      961 ttctgtcccc attaaatctg cccaataatc aatttctgtc gggtcatttg tcttcccaat
     1021 aaagaacgta ttcacattcc caatcaactg ttttcgaagg acaggatcaa ttctatcaat
     1081 gtccgcaagc gtttgagggg catacgccgc atgcacccca gcgcctcgtc ccttattgac
     1141 taagtctata aggttatcat ttagataaga agctggttcg tcaaatatta ctaggacttt
     1201 cgagcgattg gctgtttctc ctgcttgttt atacacttct gacgcaaaga aattaatatc
     1261 tcccacaagc atttgagcca atgtccgaat aaactcacta taaatcaatc cgtttaacga
     1321 gatataaaca atctttcctt ctttaacaac ttcttgaata tctaattctc tttttcctcc
     1381 agaagtatca aagagttcac caagctcact atccaataac atattgatat tggtctgtaa
     1441 attctcagaa gtcgcataca aataaaacgg gttcttctta tgttcgtaac gaacaaacaa
     1501 ccgtttaaac aacgtttgct cgatttctgt catgagagaa atgttttctt ttaataatag
     1561 ataatacgtt tctaagtcaa cggttttacg atcatgttca acgattcgct cttcacttaa
     1621 ctgttccaca tcggcaaaat cacgttctgt tttgtccatc gcttcattct ttttcgtttt
     1681 tttcttcgtg gttttcttct tttctacgac cactttttct ttaaataaat ctggattttt
     1741 caactgaata cgatccgcaa acaaatgtaa gacgtttcgt ggcaataaat aatgttgtaa
     1801 ccaaactaga tttctttcaa ttttatggct cttttggaac tcgtctaaaa gctgaatcgt
     1861 tacctgtaat aacgctttgg ctgctgtcga ataatacacg ctttctgttt ctgctagatt
     1921 ggttaattta tctcgaatgg caatatcatt gccatttttt acaggattat aacgcaaatc
     1981 gccaccgtcc acaaagactt caatcgggcg attgtatgcc tctgccactt cttttaacgc
     2041 ttgtaaagtc tctcctgctc ctttcccatc gactaagata acggggatac gaaacttaca
     2101 cgcatgttct gctagtaatt ggatcaccgt cgtttttcct gaacctgtag tcgctggaat
     2161 aatcacatgt tggttcaatt cactaaagtt catcacataa gggagcccat actcatctgt
     2221 tcctaataga atcactttgg ctaatgaagc cagttgttta ttccgcaaag caacgtcttt
     2281 tatgacaatt gctacctggt acgcttgctg atactctgct gtatattttt gggactcctg
     2341 aaatttattc ttccgacgtt ccttgtattc tttactattt agcaaagctg tttgccgttc
     2401 tttctttgaa acaacttttc ttttttcaat aaaagacgca tacgcaatca aacaacttcc
     2461 tgcacctgtc ccacctaaaa ggagggcaaa aatcgtttgt ccattaaact gcaacgcatg
     2521 agaaaacaag tttaatggaa ataataagta acacgacaaa taccctctag gaagaacaaa
     2581 aataaaacaa aatagattta atagcgtaaa acctaacgca aaaataaaaa aaagagagct
     2641 tcttcgtttt aagaagctct catactcaaa gtcataaata tgtgcacgtg tctctttttt
     2701 atctatcata aagacaatcg ctaaaggaat actgcctaca ataaaaaatg gatatagaca
     2761 aacacctaat aaagtgacga taaaataaag ttgttgaaac cgactttttg gcgtttcttt
     2821 ttcttgtttt cttttgcgat cgacagaaaa catttgctca aaatgtgtcg gtcgttttgg
     2881 tgcattcatc atactatcga tttcctccta tcgttttcgt tgtttcattt ctcttcgata
     2941 aatcggttgt ttttctcgtt ttcgtttcat ttttgcttga gttgctcgaa actcactccg
     3001 tgtcttcggt gcttgttttg gtgattttgt ttgtttcatg gttgagtatg ctttagatac
     3061 ggttgaaggc gctttggttt gtgctgttac tcgattgact gctgacatat gttcccgaac
     3121 cccctctgga cgtcgaacag atttcggtgt ggtagaacct gttgctcgtg gtacattccc
     3181 ttttcttagt ggtttttgta ccgcatgttt ttgtcctgca actgtccggg ttttcatcga
     3241 acttgttttt gttacgggag taagtgcctc cttccgacga cgacttgttt gtccctgacg
     3301 acgttttcga tcgttcaatt ctgttctagg cgtatgcttc tggccataag acttgtgttt
     3361 ttgctttgga ttcgctaatg acaccaccat tgcagaaccc tgattgcgat acggactacg
     3421 agacgcacct tttctacttc tttctcttag actaggattg ccttgcaatt ctcgttgtaa
     3481 taaatcggct gtttttcttg cctgtttctc cattgctgtt cgttgcatac gttcttgact
     3541 ttgctcttct gcttgtttcg cttgatcatg caagtctctt gctttttgtg ccatacgttc
     3601 catacgattt ggtgctttat gacgaggttg ttgtgcggat tcacgccgaa aagcacttcg
     3661 tgtggcttgt ttcgccgttt gtggcatacg aacgtctgag ccacccccac gttttcgttg
     3721 acgttcttgt ctcttccgtg cgttttcttt ttctttttgt ttctgtgctt ttctcgcttc
     3781 tttgcgttct ttcaaccgtt gtttggcttc ccttctcaat tttgcttctg ccccaaatgg
     3841 atttcccgca aaagctaacg ctcctcgaac acccattctt ccagtaaata gactgcctaa
     3901 aaagcctcgg aacaaataaa ttcccaacgg cgcaaacaaa taaacaatga tcaagagaat
     3961 tttttcccat ggatcgtctt gtgtactact taattggaac ccgtaactaa gaaaagaaga
     4021 aaaaaggata catgcaaaac ctgtcattcc ttttaaaaac gtcaaaatac caaaaacttt
     4081 ggcatagtta ccaaacacat tcattgtgac aagaaacaat cctaaaaaaa gtaagaacgg
     4141 caacatcggt actaacaata gttgcatagt tccaataatc aatcgaaaca tacttaagac
     4201 aaaataaaca acggtttgaa tcagattcac gacaaaataa aacaaggcaa atgctgtatt
     4261 tttccaacta ttgtaatatt gtatgttctt gtttttcagt gtatctgctt catactctgt
     4321 gactttgtca tgaattttct cccctatttt tgtacctaaa tcattgtcca ataaaagatt
     4381 gattcgatca tattcttttc cagcatattt gactttcttc tcacgaattg tgtctacatt
     4441 ggttgtgcca taatttaaca acagatatgg ttcataaaca ttactataaa agacccgagc
     4501 cgccatcaat ttgcctgccg tttccacttt tttatccgct gttacctctt ctgtttcttt
     4561 tgtttcataa tttgtttctt cttcaggtgt taacactgga ttgaccttca cgaacgccgt
     4621 ttccactgta gaatctaaag aaaaaagaac atcaaaaaga ttcttatttg tcccagaatc
     4681 ttttaatacg cttaacccag taaaaataag gatcgtcata agaaagacac ggagtgcttg
     4741 tttcattcga gcctctccag catatttgat tgccatcata attgccgaaa aactgattcc
     4801 aatagttcct gcaatactta acatattgtc cgcaattttt tgtgttaagt tttgaatggg
     4861 ttctcgaatg gcggaaataa tatctaattc aaagagaaat tcaaccattg aagcattgaa
     4921 ttctcctaac atttttacgc cactccaaac aaaatttttc atcactcctg caacattgta
     4981 cgatagcttt tttttaaggt tcattgactc atagtcattg gtcatcaatt caaacgaatt
     5041 ctttttgtaa tttttataca attgatccac atcagtcgtt acttctttta cttctacttt
     5101 atcgttggca ttctctcctt cagaacgatc ggtttcagtg acacccgcac catcattcat
     5161 ttgatcggca gaaacagtag ccccttgtag acagaaaaaa agacccccta ataaaaggag
     5221 cgtccaccat ttcagagatt tttttcgcaa aaaaaccacc tcttttttgt tttatcgttg
     5281 tttttcattt tctaacattg cttgaatttt ttcatcttga ttttcagtag aagaaacagc
     5341 caataaccaa ctatcaaaca acacatcaat ggcaatcggt tgatttcttc ccaaatgatc
     5401 ctggaataaa caggttcctg tttgtaattg ttccatcatt tctaaattgg ctgaattcac
     5461 ttccatatca aagaaggaca atagtttctc tcgtgcttct ttttgtttcg gacgaaacgc
     5521 aaatttgtaa gaaattaact cttttttatc ttcttgatcg taatctttaa acgcttgcac
     5581 aacaaggtaa atatccgtat tattcgcacg tccttttcgc aagctatcat caatcaaata
     5641 gcttccttgt gcggtatctt catacccttt tgcctcgtca taaataatcg cagcgtcttc
     5701 ttctttgttt gtagaaaaga tatacgtaaa cttcataatg acttccataa ttgccattcc
     5761 tgcaagttgt tcgctattta atcgacccga atcaatctct ttttgtgtcg gaatgcgtat
     5821 tccttgtgtc cctaacacgt tgatttgtga atcaaaacgt atcggcgtac tgtgctcatt
     5881 cccaatgaga atctttccta aaccaacgct atgccctaaa atcaatttag ctagttcttt
     5941 gtcacttttt cgaatttctt cgataacttg acttaacgaa tgcttacctg gcatggtgta
     6001 aactacatcg atggcgtctt ggatcaccgt tttcttgtgg ctcgctgttt ctcgattggt
     6061 atctacttct cctaacattc ctaacacatt tttagcggtt tgaattgcct cttcttttgg
     6121 taaaaacaat agaggatcaa gcatccctcg acagctttca tctgaagata acgaaataaa
     6181 attaattcgt tcatacatag ccacaaactc tggtatgtgt ccgaattttt caagtgcctt
     6241 taaaaagaac ttttgggttt catttttcgg atcaatataa agaatttttt gacctaaaaa
     6301 catcagccat aaaaaaatat attttacaag gaccgatttt cctttacctg gtggaccaat
     6361 aatcaacgta tttccattgg tatgttccgc gccttcaata cttttctttg ttaaattggg
     6421 ataataccat actagtttac tagatagcgc taacgcttct ttcgcagatt taaacttttt
     6481 tgcaataaca atccgtccta aaggaaatcc tttcttattt cctacttctt tctttaagtc
     6541 caagccataa tctgccacaa aacctgtcgt agcgacctgc tcgtaactac gaaaacgttg
     6601 cgtacttcca attaagcatt gattaaacaa cgttagctga tccgctaccg atcgataaaa
     6661 tttgaaatct gtagactcaa tcgcaaattc aatatctttg actcgttctt ccaattcttc
     6721 ttttgaagaa gcagatacaa ccagcgtgac ggtagaataa cacaatcgtt tttctttgcg
     6781 cttcagctta tcttttacat ccattaaccg ttctgtacca aaatttaata catcgtctga
     6841 atctaaaatg ccgtcaacgg tctcatattc tttttcttgt tcataaatcc gtccagccat
     6901 tttattaatt tttcgttcat cagattttga atgctcaaat cgaagtcgaa tatgcgtatc
     6961 aattggaaaa gataagctat cctgaagatt ttgaataaag ctactcccat acatggctaa
     7021 aggagcgtcc gtttgactta aaaacgtcga ataatgcgtt tgattcaact gttcaatcgc
     7081 aatgtatcct gcttcattcg aaatgacgcc ctcgcaaatt tccattggcg taagctgtct
     7141 ttcaggcaat ttttcttctg atcgatggaa aaaataataa taaatttgtc caatctcttg
     7201 ggcagataag cgctctatcg gcttataatt ggacaattcc gtatagagct ccttttctaa
     7261 tgtttcatac gttggtaaca cactacttat aggaactcgt tgtcccgtaa tacgatagat
     7321 aaacttttta aaaacatgct taagcaattg aaaatattcg atcggatcag acactttcat
     7381 ttctgtagtg aaacgcacaa acagatacgt tcgatactcg tttaattgca cttcgtcttt
     7441 taaaatcttt cctgcctgtt caaagtacac tttcccaaga tctgcgcatt ctccctttac
     7501 caaatctcga atggtttctt caatgtgcgt atctaggtta aattgacgtg gaatattgat
     7561 aaaatgatag tcatattcat catgtccaag tatgccttcg ccatcttgaa gatagttctt
     7621 gaaaaaatca atgtcattta aaggaaatac ttgggaagaa agttgatagc ctacccacac
     7681 atcatcattt ttggtcaaaa caaaatttcg gataatggcg tctatcggaa attctaatcg
     7741 aggaagcttc gtttttttct ttttgaactg ccaaatcccg ataataaaga cgaccaaaag
     7801 aaacaaaaac gccatttact cgactcactc cttccatttg tgtagggaat acgtcacttt
     7861 ttcatggaaa aacggcacat acatttcatg ttcaaagcgt tgtttccgtt tctgataata
     7921 ggacgttcgc ccaattaaat actcgaaaaa gtgtttattg tcccatttca ttgaaaacaa
     7981 tgtccaaacg agaacaccaa tcccaaaaat cataatcaac caggactttc gaaacagtgt
     8041 ctgcaagaaa ctaatttgat tcacatacgc aatcaaaaat aggatcaaaa gaatgaagag
     8101 aaatacccca cctatgacta attgttccat gcgaatgcca ttagaaatcc agggaatttt
     8161 ttgtccttta atcccgtaaa ttttgtgagg gtgcttaaac tcctttgtat agttgtattc
     8221 catgttcact ctacctcctt ttacaaaaaa agaagcgacc agaagttcta atcttctgat
     8281 cgcttttgca gtttgtcttt ttcttatgat aattgtatcc agggcacaat catttgcgtt
     8341 acccccacgt tctcttcact atccttaata aagataatgt tctttagcca ttcaccaata
     8401 tcaacggcat tcgataacaa taagacgagc attatcaaaa taaagacgcc aataatggca
     8461 aacgctgccc gcgcaaagcc ttgggtcgca taagcaccaa ccattagaac aatcgcaacg
     8521 attgccaata gccaaatgac ttgtccagat acatcatcaa ataacgattt aagatcaaaa
     8581 agtttcattt ccattctcct ctaagttcat tttattcatt taacgtagta acaaaataac
     8641 tatcgccact tgtttttact tccattgaaa agtttgattg gaactcgttt cctttctcaa
     8701 aatagaaacg atacttccct tgcaaaaagt agtttccttc tttatttttt actgcatgat
     8761 ccagttgtac attgatcaat tcgccgcctt ctaacccttt ttcgttagaa atcaatgcca
     8821 atttttcatc atttttgaca tataactcaa aaaaccgttt cacaaatgct tccagcttga
     8881 tttcttcgct ttcagtgacc gcttgcccag aagaataaaa tcgattttcc tgatagttca
     8941 cagaattggt attcttactc tcagaaagat tcaaaaattg aacgccatca agtactttta
     9001 aaacattgtt ttgataactg actggaaaag aaagttgact gcttttccaa tgttctcctt
     9061 ctgtaaaagt aacctcataa aataggcgat acattgcttg tgtcaaatcg atttcttcta
     9121 gtttaataaa gcgaacatct ttcgctactc gattggtagc cgtcgttaca aagcctagat
     9181 cagacgcttc caatccttgt gctaaataat gattgacgga agcctcccat tcgtttcgtt
     9241 tttctggcga ataagtaaat aacctttcaa taaaatgttg tccctcgtac ttcaattgtt
     9301 ccgtagaaga caaggtttgg ttgacttcag ttaacaatgt ttctggattg acttgttttt
     9361 tcactgctaa acgcgttaat gtatccactc gtccaaagtt taggaggagc acgacaccca
     9421 ttaacagaaa caaacaaaaa aaagcgcctg aaaatacact catggcactt ttttgcgaaa
     9481 attggatcat tcgatctgac ggttctgttt tctttttttg gaacaaaaaa cgtttctttt
     9541 gtttcttttc cttctgttgt ttcggtggct tagtttggaa cgcttgtgga ttaaattttg
     9601 cattactcat gagaaatgcc ataccgttct aacaataatt tcggtatttt gtccacaatc
     9661 actacttcgt ggacaaccac acttgccccc tc
//
LOCUS       DACGDM010000095         9466 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.101, whole genome shotgun sequence.
ACCESSION   DACGDM010000095 DACGDM010000000
VERSION     DACGDM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.101"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            99..293
                     /locus_tag="IXR05_002360"
     CDS             99..293
                     /locus_tag="IXR05_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260835.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            562..861
                     /locus_tag="IXR05_002361"
     CDS             562..861
                     /locus_tag="IXR05_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260836.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(958..1392)
                     /locus_tag="IXR05_002362"
     CDS             complement(958..1392)
                     /locus_tag="IXR05_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260837.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1624..2334)
                     /locus_tag="IXR05_002363"
     CDS             complement(1624..2334)
                     /locus_tag="IXR05_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4260838.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2324..3184)
                     /locus_tag="IXR05_002364"
     CDS             complement(2324..3184)
                     /locus_tag="IXR05_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAQ4260839.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3189..3827)
                     /locus_tag="IXR05_002365"
     CDS             complement(3189..3827)
                     /locus_tag="IXR05_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAQ4260840.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3842..4141)
                     /locus_tag="IXR05_002366"
     CDS             complement(3842..4141)
                     /locus_tag="IXR05_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4260841.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4184..5668)
                     /locus_tag="IXR05_002367"
     CDS             complement(4184..5668)
                     /locus_tag="IXR05_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4260842.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5688..6149)
                     /locus_tag="IXR05_002368"
     CDS             complement(5688..6149)
                     /locus_tag="IXR05_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4260843.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6167..7234)
                     /gene="ulaG"
                     /locus_tag="IXR05_002369"
     CDS             complement(6167..7234)
                     /gene="ulaG"
                     /locus_tag="IXR05_002369"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAQ4260844.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7452..8222
                     /locus_tag="IXR05_002370"
     CDS             7452..8222
                     /locus_tag="IXR05_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4260845.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8495..9322)
                     /locus_tag="IXR05_002371"
     CDS             complement(8495..9322)
                     /locus_tag="IXR05_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4260846.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2948 a         1939 c         1483 g         3096 t
ORIGIN      
        1 tgattctttt tatttatcat aaagatatag atacataatc attttcactt acatatattt
       61 gaatattaac taaaaacagc aagaaagaag aggatcaaat gtattatgta gaagtaaaaa
      121 caaaaggcgt caaaaacaaa caatatgtga aaggtatcag taacgaatat cctttacttg
      181 gttcatggaa agaagctgct cctttttcca aaccatgtgc cataaaaata aagaacgagc
      241 tagaaaaaga actgacttgt ggtaaagctg ttgtagatat catcgaaaag taaatccaat
      301 gtatagaaag gaagatcaca catgaaaagc gacgtacaaa ttgctaagat tatagaatta
      361 gaagaagaag acgcagtgtt gacaattgaa aaaaaataaa tgtttgtata ccatatgatt
      421 atttcaatat gtatcctgga attggagatc tcgtagagct atatcaagat gaatcaaata
      481 tacttgtcat tcatcatgaa atatagagac ttataaaatt gtttattttt ataatgtatc
      541 agtatagaaa ggaaataaaa catggattat actgttgaat ttgacagtga actacttaag
      601 caatttccac aagaagaaca tttcatgtat aaagaagcaa tttcccacaa agtgacagag
      661 tatttggagc ataatttttt tcgtataaag ccagtgcgta ctcgttcggc aaaaggaata
      721 tacgagatga aagtcaaaat taataaaaaa aattatcgca tagcatttgc tttaaaaaaa
      781 aatcatgtgt tcatttttta tattagttcg aatttgcaaa aaattgtatt tgataaagag
      841 gtgagtaaaa aaataaaata gctgagcatt ggaggataga ttgagtgata ctaagtctat
      901 cctcttgttt ttctaaagaa ctaagctaga attttttctt ttgtacgtta ttatatgtta
      961 tttgtcatta ccaaaaagca ccttttttct tctagtatct atgacataag aaataccacc
     1021 catttccttt acttgaacaa atcctactga ttcataaaat ttttttgttt tctcagtatc
     1081 atctgtcaat aattcgattt ggactggtcc ataactagtg atcttctcca aagcttcatt
     1141 caaaagcact ttgcctattc cttggcgctg atacctcgga tgaatgagga tatcttgaat
     1201 aaatgcgatc gtcgcaaaat cagtgatcca acgaacgatt ccgataatct tcccttcccc
     1261 attacgcttt atcagagatt cagattgttc aaatgctcta gctaaccttg cagtgtcttt
     1321 tgtgtaattc gtccaaccaa cgctcttata taattcagaa atctcatcga tcataaggga
     1381 atcaatattc atttttttct tcctttctta tacaattctc cctctaataa tacagttctt
     1441 tgactattta atctatcaca tataactctc ctgtaaagat tctctcgatt ccttaaaatt
     1501 cctctttcct tttagaatgc atactttttg ataaataaaa aggttgtgat aaattttctt
     1561 cacaacctct gtttctctct atcaagtgtt atcttttaat tttctaccct taccctagca
     1621 tctctattgc ccgtagtatg catactttcc atgtttgcga aaataatgtt tatctagtaa
     1681 atattgcggg atttcacata tattggggtt gatcagctcg ttttctttgg ccatcagaca
     1741 aatttcatct aagatcaaac tgttttctac tgctttcata ggtgaatccc cccatgtgaa
     1801 cggtccatgt ccatagacaa gtactccagg gacttcgttt ggatctaatt ttctttcctt
     1861 aaacgtctcg acaatcacat tccctgtatg aacttcgtaa gcttctctta cttcttcttt
     1921 cgttaattgg cgtgtacaag gaaccttacc ataaaaagca tcagcatgag tcgtgccata
     1981 agctggcaaa tcgcgtcctg cttgcgccca catgacggag tgcgtggaat gagtatgagt
     2041 aatagcagtt atatcttcaa aagtttgata caaaacaaca tgtgtgggga gatctgaaga
     2101 tggttttaag ctatcttctt ctattatatt tcccgacaaa tctgttacca ccatttgatc
     2161 tgcttgcatg cattcatatc tgacaccgct tggcttaatg acgatgactc ctagctcacg
     2221 gtccacttca ctcacattgc cccaagtcaa tttgactaat ccgtatcgcg gcaatgccag
     2281 atttgcttca aggacacgtt gcttcattgc tgcaattttt tcttcacaag acatcatagc
     2341 cagcctcctt caatttagaa cttaagtagt cttttgcctg ctggatttct cttcgaaagt
     2401 cttggctttt ttcactccac atttcaatca gaaatgttcc atcataatct agacgtttca
     2461 aatgtcttaa taatccaaga aaatcaacac aaccgctacc aaaaggaaca tcacgaaact
     2521 ggcctgaata ttcttttgtt acagggtaag tatcttttaa gtggatagca gtgatataat
     2581 cgatcccttt ctcaagttct cgagccggat tattttccgg ccatgcggac aaattgccta
     2641 ggtctggata tacttgtaga aaaggtgaat gaatctgttc tttgatttct aaaaattttg
     2701 aaatggagtt cataaatgga tcatccatga tttccacgga aagaatgatg ccatatttag
     2761 aagcttcctt tacgctttct tttattcctt cgataaagtc ttctctggaa ttcattgatt
     2821 tctcttcata ataaacatcg tatccagcta tttggattac tttgacgctt agattatgcg
     2881 ccaaatggat tgcttttttc attagttgtt tcgctgcttt tttcttttct ggatcagcag
     2941 aaccaaacgg aaatcgccga tgcgcactta aacaaatcga atggatacgt acaccggagc
     3001 tgaacatctc ttctctcagc tcagctatct tttcttcaga ccaatctaat cgtgctaacc
     3061 gctcatccgt ctcatcaatc gacatctcga taaaatcgaa gtccatttct tttacaaggg
     3121 aaaaacgttc tttccatgaa atatctttgg gtaacgcttt ttcataaatc ccaatttgag
     3181 ccatttcctt acccccagat acgaatgatc tcatctttga agttttgtgc ggccttcatc
     3241 ggatcatttg ctgctgtaat accacgacca gtgataaagg tatacacatc gatcccttca
     3301 aataagtgta atgtgtgtgg atttaatcca ccagttacag aaacattaaa gcctagttca
     3361 atcagttttt tgatcttcga taaatctttt tcaccccaag tttcaccaga taacagcgca
     3421 tcacggcttt gatggtagat tacctgccgg ataccgatgt tatgccaatc catggcttgt
     3481 tcaaaagtcc aattgccgta gagttctact tgcaattcac ctatttcttt ttgtgctgcc
     3541 tccatagttg gaatcgttgc acaacaaatg actgtcatcc agtctgctcc tgcttttgca
     3601 acattactcg ccactgttcc tccagcgtct gcacatttcg tatcagcgac tagtttttta
     3661 tctgggaaca tactgcgaat acagcgaatc gctttttgtc cttcctgtaa gcaaagaatt
     3721 gtgcccactt caataatatc tactacatca ccaactttca taacatctcc taatgcatgt
     3781 tctaagtcat tgtgatctaa cgcaatttgc aaattcggcc tgctcatctt agttccttcc
     3841 tttacttgtt tttttggtac cactttgttt cagcaaattt ttcactgatt tctttgactg
     3901 acatcacatt tttgataccg ataactgtaa ctcctttttt ctctgcctga gtaaacatat
     3961 tcaaaaaatt gactggcgta aaaactacat cgtattggcc agctgaactt tttccctctg
     4021 aaatggcaca atgatggatt ttggtaattg gtacgtttag ttctttcatt gctttttcca
     4081 cacttctcat catcatcaag cttgttcctg atccatttgc acacgatact aaaattctca
     4141 tcttaatccc tccattatga gtgttgtcta atcagatttt cttttatact ctctgctttt
     4201 ctgcatatgt gtcatagtct tctacaatca aaaaataacc atcaggattt ttccgatatt
     4261 gtaactgcgg aatagccaat aaaccaatga caactacggc aattccagca taacctagga
     4321 ctttcatgat tactgtaaac aatggccaag ctgttgccca gtcgaacatc ccgatataac
     4381 caccgtatgt tgacatccca atccatgtag cgaataatgc tgaaccgcct acttgtatga
     4441 ttcctgaaag aaacgggaac aggcaagcgg ctttgaatcc acctcggtta ttggcataaa
     4501 ctgctataac ggcattatca aagaacaacg gaatgaaacc ggctatgacg atcgttggtg
     4561 atttcaataa aatcagtaaa ccaatcatca aaaactgtcc caaagcacca aacaagaacc
     4621 caatcgttac cgcatttggc gaaccaaagc caaaagtagc agctacgtca attcctggaa
     4681 cagctcctgg taaaatcgtg tttgagattc cttggaaaga ttgagttagt tcatcgacga
     4741 atgtccgaac acctaattgc aagatcgcca gatataccgc aaaatttaaa gaagtcgtca
     4801 taatgtagaa taagaaactc tgcccttctt gcatgaattg cgcttgaatc aaataatctt
     4861 tgcctagtac aatcagaatg atcccaaaga aaaatagcat gagtaacgaa gtagcaacca
     4921 tattctcatt gaaaatcgac aagaatcctg gtaatttgat atcttcaatt tttttgtctt
     4981 gcttgattga tctatttttc ttttcatccc gctttttcat ccactcagct aattttgcaa
     5041 atataaagat tccgaacatt tgctgatgtg ccactgcaaa tccggcacct tctgtcaatt
     5101 cctgcgtgat tcctactgtt aagttagaag ctactgtcca ataacaacct aaaatcagtc
     5161 ccataaaaat caatgcttgt atcctaccta gatcaggaaa gcaaaacagt aaaatccaaa
     5221 aagcggtagc tgcttgttga acctgaacgt ttccggtagt gaaaacggaa cgcagtttcg
     5281 tatatttctg aaaacggact aataagatat ttaaaacaaa tgcaatcagt aataaaatca
     5341 tcacatctcc aaaggtacgg ccaaatgtct ccattaatcc agcatccaca gcattttgtc
     5401 caaaataagg atctgtaacc atggcatcca aattgaaccg ttcctttagt ccaaccaaga
     5461 ttggccgaaa attattgacc aaaccaccag agccaacagt caaaataaag taaccgaccg
     5521 ttgcctttaa gaatccagcg atgcattcat gaagcgggcg tttcagcaaa atatagccta
     5581 ataacacgat aaaaccaatc aggtatgctg gctgcgtcaa gatatttgtt gcaaaatacg
     5641 tccaaatgct taacaaaaat tcccccatct tttttctcct ctatcaatta attatattct
     5701 gccatcacaa cttggtaatc atcgatggag ttcgtagaga tgagacgctc aaccaatcca
     5761 tctgtcatta ataattcgga taatttttgg atattttcta gatgttcttc tggatctttt
     5821 gctgcgagtg taaaaaacaa actagccgtt ttctcctcat tctccccttc actttcaaaa
     5881 cggattggct gtttcaactt ggtaaatgaa atagctgttc caaaaacacc atcacttttt
     5941 tctgaagaat gcggcattgc tacttgaggt gcgatcacaa tataaggacc gtatttttct
     6001 acacaatgga tgatctcctc cacatacgtt tcatcaataa tttccttatc gatcaataca
     6061 agacagcttt cggcgatagc ttcacgccaa tccgtgattt ctttatctgg gtaatgaatc
     6121 aattgatggt caaaaaagta tttcagcaag aaactcccct tctttcttat aaaaacgacg
     6181 gaaacggtgt atcattttca atcgagaaga catcttcaaa tcctcgataa aaattaaact
     6241 caagatcatc tttgtttgtc ggatagatga atttcccgcc tacttgccag atataaggtt
     6301 taaatccata cttcaggcga tcctttttga atttccaaat ttcagtgatc tcttttggat
     6361 cagccataaa attagaccaa atatcgtagt ggacaggaat cactactttt gcattcaatg
     6421 actccgccat gcgcagcata tcaacagaag taactttgtc tgttatccct cgtgggtttt
     6481 caccataggc ccctaaacag acatcgattt tgtgttcatt accatgtttg gcaaataaat
     6541 tggagtaatg tgaatctcct gcatgataaa gattccctcc tgatgtttcg aataaatagt
     6601 ttactgcaat ttgatccatc tcctgaggca tttttccttt taatacctct tctggatctt
     6661 cacaagtgac caacgctgtc cgatcaaacg cttctaaagc tactacattg atgtctttga
     6721 ttttgactgc atcacctggc tttactgtaa tcgttttttc ttcaggaatt ccccattttt
     6781 gccacgtgcg aaccacttct tttggcccaa tgaatgttgc ttcaggacaa ttttgatgaa
     6841 ctgctgcggc tgtatggata tctagatgat cggaatggat atgtgtaacg attaaagcgt
     6901 ctacattttt tatcgcaaaa ggatcgatta cgaaaggctg agtacgtaaa ttaggctgca
     6961 tattttgaac gccactcata cgcatcatct gatggccttt tttcatcatg ccattcccat
     7021 gactacgttt tcccgtccca caccatagat cacataaaat attcgttcct tcatgacttt
     7081 tcagccaaat tcccgtacag cccagccacc acatagcaaa agttccagga tccactactt
     7141 ctgtttcgat ttcttcattc aagtatgtgc cccactcagg aaatgtttct actaaccact
     7201 tttcttttgt tacttcattg acagttttac tcatttgctt gctcccccca tatcgttgtt
     7261 ccaacttaca agtaaatatt aatgtgtatc agcatccatg aaaacccttt tatatgaccg
     7321 tttgtttttt atatgatttt ctttcagtaa tcaatgattg tttcagtata ataaagacag
     7381 atatgaatgt ttaaatgaac aactagtcaa ataaatccat ggatcaagat gtccctcagg
     7441 aggcaaaagt catgaaaaac tcacttgtca atattgaaaa acgtcaaaaa gaaattttgg
     7501 aactgcttca gcagactgaa caactatcaa ctttcgaatt agctgaatcc cttgatgtat
     7561 ctattagtac gatacgaaga gatttaaatt tattagaaga aaaaaacgag atcatacgca
     7621 attacggtta ttgttcttat aattacaaaa accagactga ttttgatcaa tctggtcctg
     7681 aaaggattaa acaagcgatt gccagagaag ctagtaaata cattaacgat tatgatacgc
     7741 tgtttatcaa ttctagctcg actgcgttga aaacactgga ttttcttcaa tctaaccatt
     7801 tgacagtcat tacaaacaac gtgaaaatca attactctcc gcacaaagat aattgtagtt
     7861 atattttaac tggtggagag atgcgctttc caaaagaagc actagtgggc gacatcgcat
     7921 taaatacgat ttcttcagtc aatgcagaca tttgtatcat tggctgtagc ggagtcgatg
     7981 tagtacatgg ggtcacaaca aagatattaa atgaatcaac gatcaacgaa atgatggtca
     8041 acaagacaat caaatgtaag attttagtcg ctgatcatcg aaaaatcgga ctgacatcaa
     8101 agttcaagat tgctgatatt tcagtctttg attatttgat cactgataaa ttttgttctg
     8161 aaaaagtatt agaggagatc agaaatacgg ggataaaaac cattcaagta gattcatttt
     8221 aagaaccagg acgtaaatat gtaaatagga ttatcaaaaa aatgaataac aaatttatcg
     8281 ataaatgaaa aacacgctac gctcaaattg ataaaggaat cccaagatgt atccatccaa
     8341 tcgataccat cataatctat tgcttctttt ataaccgtta tatgttgcct aaataggaat
     8401 caaacaatat cgaaaaaagg aggtatgaca aaagtcacac ctcctttttt cgaataaacg
     8461 gtattcaaat cagaacactg atttcacaac cactttattt caggtcgttt tcaatcacct
     8521 ttaccgcgta atcatttccg ttgaaacgcg ctattttttt tgcgtccata tatctttcta
     8581 aataatcatc ttctcctaat tgcttatggc aagaagcaat ttcataaagc aagtattcca
     8641 atgcataagt cgatttatgt ttcttattat actcaatacc cttctcacat aattggattg
     8701 ctttatcata atcctcgatt ttacggtaat aggtggcgat atcataatat acaatgcaga
     8761 ccatcagatt atcaaaatca gtctcactca atattttaag tgtacgctcc acataaactt
     8821 tcgcaaaatc taattctcct tttgacaagt agatcattgc cacgtttgca gctgcttgta
     8881 agtgatggat atctgtttcg gtcgtttgtt ccaacacttg attaaaataa aataatgctg
     8941 catctggttt tttcgcataa agatgatcaa gcagtccttg ataaaataaa atttgattta
     9001 aaagatcaga attacttact ttttcctgat cgatcgtttg taaaatttta taagattctt
     9061 ggtattttga tacagaattc aatgattgaa tctcatttat ttttttcctg attttgtctt
     9121 cttctgtttc tactaatata tcggagatct cgacattcag ctttttgcaa agcgcactta
     9181 agatattgat gcctggcgac atattcttgt tttcgatatt gctgacagtt gcttgttcac
     9241 aaatgccttc tgctaattgt acttgtgtta accccttttt ctttcggtat tcttttagta
     9301 atgctccatc tactttaatc aaaacaattt ccttcccttt aaaaaattat ttctccttta
     9361 tatcatacac aaaaaaaagt tctaaacaac caaaaatgtt tagaacagaa taaaaatttt
     9421 aattttaaaa taatattcaa attaaacaac tggcgtatct gctcct
//
LOCUS       DACGDM010000096         9362 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.102, whole genome shotgun sequence.
ACCESSION   DACGDM010000096 DACGDM010000000
VERSION     DACGDM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.102"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(93..761)
                     /locus_tag="IXR05_002372"
     CDS             complement(93..761)
                     /locus_tag="IXR05_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4260847.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            895..1182
                     /locus_tag="IXR05_002373"
     CDS             895..1182
                     /locus_tag="IXR05_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260848.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1598..3136
                     /locus_tag="IXR05_002374"
     CDS             1598..3136
                     /locus_tag="IXR05_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAQ4260849.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3133..4098
                     /locus_tag="IXR05_002375"
     CDS             3133..4098
                     /locus_tag="IXR05_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260850.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4085..5407
                     /locus_tag="IXR05_002376"
     CDS             4085..5407
                     /locus_tag="IXR05_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4260851.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5470..5574
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5648..6391
                     /locus_tag="IXR05_002377"
     CDS             5648..6391
                     /locus_tag="IXR05_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4260852.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6406..7398
                     /locus_tag="IXR05_002378"
     CDS             6406..7398
                     /locus_tag="IXR05_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4260853.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7410..8147
                     /locus_tag="IXR05_002379"
     CDS             7410..8147
                     /locus_tag="IXR05_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260854.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8137..8859
                     /locus_tag="IXR05_002380"
     CDS             8137..8859
                     /locus_tag="IXR05_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4260855.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8943..>9362)
                     /locus_tag="IXR05_002381"
     CDS             complement(8943..>9362)
                     /locus_tag="IXR05_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAQ4260856.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3069 a         1607 c         1972 g         2714 t
ORIGIN      
        1 atttttttat aaagaagatt ttactgaata atatcatttt agtttacata atgatatttc
       61 tgtaaattaa ataaagtagt gaaaaataag aatcagtgct ctaactgttc aagaggatca
      121 agtggttcaa atgtttctgt agtctgtttt gcttccaatt ggggcaaaac agatccaatt
      181 tccagatact tcactttatt caatgtataa gatagaatag aacagctaag taatgtatac
      241 agaaaatgtg tgagatccaa ataaagcaag gagacaacta aaataccaaa agtaatcaag
      301 aaaagacttt tgccaatctt aatatgaaaa tatttttcaa tggcttgata aatgatatct
      361 gttccgcctg tgcttccgcc gaatcgaaag acgagaccgc aaccaatgcc agaaagaata
      421 cctgtcatca aactattgat cagtagacta tctacagcaa aatgtatatg aaggctctcc
      481 cataaatgta aaaagaaaac tagcgcaaat gttccgacga tcgtccggag aaaagcgtgt
      541 tttccaaaaa gaaacaatga gataagcaat aaaggtaaat taaaaagcag tgaagtgaca
      601 gaaggagcga atccaaaaag attatgcaaa agcaaagcaa taccagtaac cccaccatct
      661 gccagcttag atggaatatt gattcctgtc acagctaatc cgtagattcc tgcgcctaaa
      721 atgattccgc acaattctgt aaataaattt aattttttca tttctagcct cttttctttt
      781 gaaaattttc agcaacttct ttattatact gacttatact cttacttcaa gaggaaaatg
      841 aaaaaaaatt atttttggct gtttcttttt atttatcaaa taaggagtgg aaaaatgcga
      901 gcagcagact tattgacaat tcttacaaaa tcacccaaaa aaacagagta tcaaggagtt
      961 tttttggctc aagaacaaaa actggtgcct gtgacaatgg tccagataaa taaagcaaat
     1021 caatttatct ttttatttga acacggcaaa gcaccacttg ctatgaaaga catctttctt
     1081 tttttgatga agaaccgtga gaaagctgtt tattatcagt caaaagaaga actcattcct
     1141 ctttatggag tgaaagagat agaaaataaa gtggtgatat aagtaaaaat aagaaaacaa
     1201 gacgtttatg atgtcaaaac aaccattttt tacatttttg gcaaaaaagt gtcatgatac
     1261 agtataatat tcgttgaaca ggccaataaa ggtgttctcc cccacgagat ttctacttta
     1321 ttggctgttt ctttttatta aaataaaagt tgtgtgtgta aaaaagatat agctgattcc
     1381 aagtgacaat ttcgtataga tttttatggt attcgtagtg aaaaaacgag aaccaaaaag
     1441 ttgatccgac tttgttgctt ggattctttt tttgtcagca tatttagagg tatttttttc
     1501 ttttttttgt tcgtgctgta aggttaaggc aagacaagtt agttgggaaa aaggaaagaa
     1561 atgtttatac ttaaagaata acagaaagga aggtcgcatg aataatttta tacaaacatt
     1621 aagtgaaaga aaaggcgagt tgctggaagc tgcatttcaa catctgtcca tttctctcat
     1681 ttctttgctg attgcagcac tgattgctat tcctttagcg atttgggcag ccaatcataa
     1741 aaaaatggca gaagtcttat tgcagatcac gggtgtgctc caaacgattc cttcacttgc
     1801 cttattaggt ttacttatcc catttgtagg gatcggaact gttccagcat tgattgcact
     1861 tgttatttac gctttgcttc cgattttcca aaacacgtat attggtctag ctgaaattga
     1921 cccgtctatt gaagaagcag cggtagcatt tggtatgtcc agaatgagac gcttgctgaa
     1981 agtagagctt cccatcgcat tacctgtcat tatctcaggt atccgaactg ccttagtttt
     2041 aatcatcggt acggctactt tggcagcatt gatcggagca ggtggattag ggacatttat
     2101 tttgttaggt attgaccgaa atacacctgt tttgacattg attggtgcga tcagttctgc
     2161 cttgcttgca attatattca gcggactgat tcgctggttg cagcataaga aacctcgata
     2221 ttccatcatt actttagcag cagtggtgtg tttatttggc ggcgtttctt tatatcagtc
     2281 tgccttgttt aaaaatgaaa ccatcacgat tgctggaaaa ttaggagcgg aacctgaaat
     2341 cctgatccaa atgtataaag aattgattga agacaacaca aaaacagaag ttgaattaaa
     2401 accgaatttt ggcaagacga gttttttgtt caatgcactg gatcaaggtc aaatcgatat
     2461 ctatcctgag ttcacaggta ctgtcctaga aagcttggtg aaggtacctg aagcaatgaa
     2521 aagtgctgat ttgacaaaag aaaaaacata tgacgaagca gaagaattat tgaataagca
     2581 attcgatatg acattattaa aaccaatggc ttaccaaaat acgtatgcct tggcagtcaa
     2641 gagatctttt gcgaacgaac atcaacttaa aaagatttcc gatttggcag ctatctctga
     2701 tcagatcaaa gcgggattca cactggaatt tattgatcgt tcagatggat ataaaggaat
     2761 ccaagaagca tatggcttga atttttcaag tgtacaaagc atggagccaa gtttgcgtta
     2821 ccaagcaatc aataatggag atgtcaatat tgtggatgcc tattccacag atagccagct
     2881 caaggagtac gatctagtga ctctagaaga tgatcgaggg ttattcccag cttatcaagg
     2941 cgcaccgctg atgaaaaaag attttgctaa agaacatcct gaaatcgtta aagcactgaa
     3001 taaattaagc ggaaaaataa cggaggatca aatgattgat atgaattacc aagtcaatgt
     3061 cgaaaagaaa aagccgacag aagtagcacg aatcttcctg aaaaatgaag gattagtaaa
     3121 ggaggaagat cagtgactaa attaatcgag ttcaaacatg tgcaaaaaaa gtatgatgga
     3181 aagtatgtca tcgatgacct aaatctggca atcaaaaaag gagaaatctt tgttttggtt
     3241 ggtccttccg gtagtggaaa aacaactact ttgaaaatga tcaatggatt atctaaacca
     3301 tcagcaggag acatctactt caaaggaaaa tcgttaaatg aatataatct gcagaaaatg
     3361 cggtggaata tgggatatgt gctgcagcaa atcgctttgt tcccgaccat gacagtcaag
     3421 caaaatattg aagtcatccc tgaaatgtta ggttgggaaa agcagaaaag agcagaccgt
     3481 gtagatgaac ttcttcaaaa agttggctta tctcctgata tttatcgaga tcgtatgcct
     3541 agagagttgt ctggaggaga acagcaacgg atcgggatca tccgagctat tgctgcaagc
     3601 ccagatgtga ttttgatgga cgagccattt agcgcattag atccgatttc aagaaactca
     3661 ttacaagaat tggttttgtc cttacacgaa gaattgggca cgaccatcgt tttcgttacg
     3721 cacaatatgg aagaagcaat caagctaggt gatcgtattg catttatgaa ggatggagaa
     3781 attatccaat gtgacacacc agagcagtta ttgatgaatc ctaaaaacga ctacgttcgg
     3841 catttctttg atgaaccgaa acagacgaaa gagtggcgag tagaagattt agtcgtcaat
     3901 ggatatttct taaatgaaat accagaaaat gctcgtcaac aagtttgctt tgatacgcct
     3961 atgaaagaag tatattcgct tctttcggtg tatccaagca ttgtgatagt agaaaagcaa
     4021 agaagtattg ggtcgctgac aagtaaagaa atctttgctt ttttaagtcg agaggaggaa
     4081 ggaaatgaaa acatatgatg caatcatcat cggttcaggt gtgagcggct taagtgctgc
     4141 ttatggattg aaagaagcag gtaaaacagt actagtggtc gaagaagatc tatggggcgg
     4201 gacttgtcct aaccgtggat gtgatcctaa aaaagtcttg ttaagtgcag tagaggcacg
     4261 taatcgggta aaacaattga gtggaaaagg ttttaacgag atcccaactg ccaactggga
     4321 agaacttcaa aaattcaaac gaacatttac ggatccagtc ccagaaagcc gaaaaaaaca
     4381 attagcagaa gctgaaatcg atcatctttc aggaaccgct cgttttttgg atgattcatc
     4441 tattgaagtc aacgaagaag tcttccatgc ggattactta gttttggcaa ccgggcaaag
     4501 acctacgatc ttaccagtgg agggaaagga atacttgaaa actagtgcag actttttatc
     4561 attgcctgta ctgcctaaag aaatcatttt tatcggtggt ggttatattg cttttgagct
     4621 agctacgatt gccaatgctg cagggagcaa agtaaccatt gtccatcata atcaacggcc
     4681 attaaaagaa tttgaggcgt ctttggtaga ggaagccgtc catcaaatgg aagcatctgg
     4741 cattcagttt gcttttggtg ttgaaaccca aaagatcatt tcagaaggta ctcgctatcg
     4801 tttagtcgga aaagagacgg aattagtagc agatatgatt ttttgtgcga ctgggagaca
     4861 gccgaataca gaatctttag cacttgagca agcgaatatc gtctttgata aacacggaat
     4921 tgcagtcaat gattatctgc aaacgagcaa tccaaaaatt tttgcgtgtg gagatattgt
     4981 ttcaaggaaa accccaaaat tgacaccagt cgccactttt gaaggaaatt atgtagctaa
     5041 gcggataacg gatgcaacaa gcgaacctat caaatatccg attataccta cgatcgtcta
     5101 cgccagtcct aaacttgctg aagtaggagt tacaaaaagt cacgcctctt cgtcagatca
     5161 agtggtagag atggatctta ccagttggtt cacctatcat cgtgtcaatg aaccagttgc
     5221 taaggctgaa ttgacctttg accagcaaaa ttatttgatt ggtgctgcag tgattagcga
     5281 gcaagcagac gaattgatcg atgatttgac actcgtcatc aatcaaaaat tgactaaaaa
     5341 agagttggat agctatatca tggggtatcc gacattggca agtgatctct cctatttatt
     5401 gaaataatca gcatgataac taaagcgctt gttgcttttt ccttcttgtg ctacacttta
     5461 aaaaatgaat acctgtttct ggggatgtcg tagacgacat gagagtaagt tgtgaactta
     5521 gacccattga acctgtcagt taatactggt gaagggagaa acatagcaga cgcttgaagc
     5581 gggttactat gtcgtgccca tttcaagcgt tttttgttat tcatattaga agaaaggagg
     5641 taacaaaatg aagaaaaatc tttatccagc agtcagtatg gcattcattt taattatttg
     5701 gcagattgtt gtcatagttt ggaaaatacc tgcctttatt ttacccggac ctgctgctgt
     5761 attttctgca ttagcggcag atgcacaagt attactttcc cattctgtca cgacattaaa
     5821 tgaagcagtg cttggtttgg taatagctag cgttctttct tttattactg ccttggcaat
     5881 ggattattgg aagtttttag aaatgtcttt ttatccgtta ctagtgattt cacaaatgtt
     5941 gccaatcatg gtgttagggc cattacttac cctatggttt ggtttcggta tgcttccaaa
     6001 agtgatcctt gttgtcttga taagctattt tccgatcgta gtttcttttt cggatacatt
     6061 gaggaaagta tcaaaagagc aaatcatctt tttgaaaacg atgggggcag atacagggaa
     6121 gatttatcga atatataaaa taccagcggg tttatccggc ttcttttccg gtttaaaagt
     6181 ggctgctact tattgtgtca gcggagcagt cgttggagaa tggctaagcg ctcaagcagg
     6241 cttagggtat tacatgatac gcgtaaaaaa cagctaccag atcgataaag tttttgctgc
     6301 gatcatttgt gtcattctat tgagtttatt gctgaatggc gcttgttcat tattgaaaaa
     6361 agggtattat cgtatgcttt atatttttta agagaagggg atcaaatgaa aaaattatgg
     6421 cttttattac cgctactgtt gcttttatcc gcttgtggca ctgcaaaaga aacaagtagc
     6481 aaacaagaaa taaaggattt gaaaaaagtg acacttgttt tggattatgt accgaatact
     6541 aatcatactg gcatctacct agcaaaagaa aaaggctatt ataaagaggc tggtttaaat
     6601 gtccaaatca tcgaaccagg agataattcg acaagtattg gtctagtagg tgcggacaaa
     6661 gcacaatttg gtgtaagtta tcaagaagat gtcacttatg ctcacgcaga tggacagaat
     6721 ataccagtca aagcaattgc tacagtgatc aaacataata cttctggatt cgccacccta
     6781 tcagacagta acatccattc accaaaagat tttgaaggaa aaacatatgc aggttggcaa
     6841 agtccaagtg aagaagctgt cttaaaagct gtgatggaaa aagacggcgg ggacttttca
     6901 aaactgacaa tggtaggaag caatggagaa gggccagaaa gcttaggaaa atcctcagat
     6961 atccaatggt actttgaagg ttgggatatg atcaaagcaa aagaagcggg tattgaacta
     7021 aactatatcc cattgaaaga attagatgaa cggttagatt actatactcc ggtaattatt
     7081 acgaatgatc aactgatcaa aagtgatcca gaattggtac agtcttttat ggatgccacg
     7141 aaaaaaggct atcaggaagc tattaaggat ccaaatgaca gtgctaaact gttgcaaaaa
     7201 tatgcaaaag aaaatgatcg gacgttttta gaagaatcac aagcattctt gtcaaaaaat
     7261 tatacggatg atcctgagaa ttggggattg atggaagaaa aagtttggcg caattataca
     7321 gcttttatgc aggaaaacgg attgatcaag caagatgtac cttcgcaaga actattcact
     7381 aatcagttta taaaatagga gtgatagata tgtcaatcca aatcagccac ttgaatgtag
     7441 tcattgaaaa cctgaaaata ttagaagaca tccatttcac tatccctaaa gataccttta
     7501 catcgattgt cgcgccaagc ggagccggta agtcaacatt gctgaaaact ttaacaggag
     7561 tccagcctat gacttctgga acgatcaaag tagacgatca aaaagtaact ggtctccata
     7621 cagcatttag ttatatgccg caagaagata tgttacttcc ttggctgagc gtctatcaaa
     7681 acgttacgtt atatcaaaaa atcaatcatc taacaatcaa tgaagaacaa gtaagggatt
     7741 atctggatat ctttgggtta aacggctatg aacatttttt gccggaacaa ttatctggcg
     7801 ggatgaagca gcgaacggcc ttgttacgaa caatcatgaa tccttcttct tacttgcttc
     7861 ttgatgaacc atttggagcg ttagatgcta tgaccagagg gcagatgcaa gactggatgt
     7921 tgaagctgcc taaaaaagca aagcggacta ctttacttgt gacgcatgat atcgaagaag
     7981 caatttattt atcagacagg attcttgtgc tttccgcccg tccggcacat gtgattgctg
     8041 agattcaagt gcctgaaaaa cgacggtcac gtgaatggct actgcagcaa tcagagttga
     8101 agcaaacgat ttatcagtta ttggcaggtg aattagatgt taagtgatgc tcattgtcat
     8161 ttagatggga gtcagagttt agcactcctt cagcaggaac acacgatttt gacgatcatc
     8221 aattgtgatt cgccagaaga atggaaggaa aacagacagc ttgcagcaag taagactcaa
     8281 gccttaagtt acggtatcca tccttggaaa gcagatagct atacgtttga acaagttgag
     8341 ccttttttga aaaaagcaag gatcatcggt gaaatagggt tagataatat ttggacgaat
     8401 gtaccgatga ctacacaaaa aaaagtattt gagcgacagc ttgcttttgc agccataaat
     8461 gagaaacctg ttgtactgca cacaaaagga tgcgaaaaag agatcttaaa ttatatccaa
     8521 gcttacccta atcactattt gatccattgg tattcttctt tggactatca acaagactat
     8581 attgatttag gctgttattt cagcattggt cttgatttga aaaagaatcc agcagtctgg
     8641 caactagcta aagcagtccc aatcgaccac ttacttattg aaacggatgg actacatgca
     8701 gcagagtggg ctttaggggg gattttttca gaaaaagatt atgtctcact gcttgaagaa
     8761 cagttaaaga caatcgctga gatcaaagag ctatcagttg aagaagttaa aaaaaatact
     8821 tatcaaaact tggaacgttt cattagatta ggtaaataaa aaagagatgt gacacaacta
     8881 gtgtcgcacc tctttttggc tttctttgta taaaagtaaa ctgtttgatt aataaatgaa
     8941 tcttagtacc aaccgtttgc ttcccagaat gctttcgccg cttcccaaga accataacgt
     9001 gaagtaacat attgttctgc tactctttct tggtttgcag cagagtagtc accatttaag
     9061 taagaagaat ctaattggta acgtccgatg taacgtccgt tcgttgctgt gtaagaaccg
     9121 cttgattctt tttgtgcgat ccattctttt gcagagcttg tgcttgctgg agtagcagca
     9181 gtttctgtta cagcaggagc aggttgtgtt tcagcaacag gcgctgcttg tttttccgtt
     9241 tgaaccgttt cttgtacaac aggttgttca gcttggactg gtgcttcttg aacggctgct
     9301 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
     9361 ta
//
LOCUS       DACGDM010000097         9174 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.103, whole genome shotgun sequence.
ACCESSION   DACGDM010000097 DACGDM010000000
VERSION     DACGDM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.103"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..323)
                     /locus_tag="IXR05_002382"
     CDS             complement(<1..323)
                     /locus_tag="IXR05_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260857.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPP"
     gene            complement(620..3001)
                     /locus_tag="IXR05_002383"
     CDS             complement(620..3001)
                     /locus_tag="IXR05_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4260858.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2991..3638)
                     /gene="recU"
                     /locus_tag="IXR05_002384"
     CDS             complement(2991..3638)
                     /gene="recU"
                     /locus_tag="IXR05_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAQ4260859.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3702..4241
                     /locus_tag="IXR05_002385"
     CDS             3702..4241
                     /locus_tag="IXR05_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAQ4260860.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4331..4750
                     /gene="gpsB"
                     /locus_tag="IXR05_002386"
     CDS             4331..4750
                     /gene="gpsB"
                     /locus_tag="IXR05_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAQ4260861.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYEAYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4772..5139
                     /gene="rnpB"
                     /locus_tag="IXR05_002387"
     ncRNA           4772..5139
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IXR05_002387"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5348..6514
                     /locus_tag="IXR05_002388"
     CDS             5348..6514
                     /locus_tag="IXR05_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAQ4260862.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6560..8056
                     /locus_tag="IXR05_002389"
     CDS             6560..8056
                     /locus_tag="IXR05_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAQ4260863.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            8137..8820
                     /locus_tag="IXR05_002390"
     CDS             8137..8820
                     /locus_tag="IXR05_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4260864.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         2929 a         1630 c         1921 g         2694 t
ORIGIN      
        1 ggcggtttca ggctcatcag aaaaatatag attctggtga acaacaacca taaaaaagtg
       61 agaatcattg catgagagct tctttccata aattttcctt taagagtagt gcttaaaagt
      121 acagaaaaaa taataaatgc aaggatagga gcaattaaag taaatttatt taataataaa
      181 caaaattttt cagctttttt attcttggaa taacgaggta ttgttttcga taaaaaaaga
      241 tggtgcagac aaattatgat aattaagcat actatcagat aactcaaaat gaagccttct
      301 ttcaaaaaat tattcaaaac catatattgt attttttatt tgataataac aatgggatta
      361 ttaagaagtg gcactaaata aaagactagt gtgtatttag ccgatttaat tataaacaag
      421 taaatggata aagtatatgt aatgataaaa gaaaaatgga ttttctaatt tttaagctaa
      481 atgttagatc acacatgtat atgctggata gtcttataaa aaatcatgta atacagcttg
      541 gtacatgatt tttatttgta gctgtttttt acatagacac aaaaaagaaa ccacgcttgt
      601 agacgtggtt tcttttttac tatctgtttc cagaagctga ggtgctgctg gatggtgtat
      661 ggtcatttgc agcatccgct ccgctagttg ctggctcact ggaagaagca ggaggagcag
      721 atgaagacgg tgtcgagctt tcttcggatg aagaagaagg aaccgttgtt gaagacgctg
      781 gctcgcttgt ttctgctgtc gtgctttctt ttgaggactc agcagttgat tcgctttgac
      841 tagtagagct agagctttga gtcgttgtct ctgttgttga gcttccagga gtctggacat
      901 agctggaaga tggaatagtt gttgatggtg taattgcatt cgatctagct gtatattgat
      961 ctttgtagta cagttcaccg cccacacgaa ttaatccgct tggcatctcc cagtctgtat
     1021 ttgtcacgtt agctgaaaca tactgcataa gctcgcgata aacatcagag gctacgtgtg
     1081 acgattctga agtgacaggt gtcatttttt tattgtaacc tgtccacacg gaaatcgaat
     1141 aatttggcgt atagcccgca aataggatat ctggatacac cccagaagaa ataccaagtt
     1201 ttgcatactc gtcatctgtg taattggatg ttccggtctt accggcttga tataacccag
     1261 cgatttgcgc attcgtacca gttccttcag tgatcgtatc ttttaaaatg tctgtgatca
     1321 tataagctgt ttctggagac atggctgttt ttccatctgg ctcataagtt tcttctgttc
     1381 cgtcttggaa gacgatttta ttaacatatt gaggtttgta ataagtccct ccattggcga
     1441 aagccgcata ggctgctgcc atttttaagg aagaagctcc gtattttgtc ccatcttgtt
     1501 cttccgtatt actagagatc gcattcgatt gatggatcgt actgtattcg atcccaagat
     1561 tttttaagaa agaagccact ttatctgaac cgacttcatt gaataatttg actgctggaa
     1621 cattacggga taagtaaagt gcttggcgta aagtaatggt gcccatatat tgattatccc
     1681 agtttcctac aggagtcgaa gtcccttcat agttatacgg tgcgtcagta atagtttttc
     1741 cagtagaata tttcaaatat tcaaaagctg gtccgtaatc tgtgacaggt ttcatcgtag
     1801 aaccaaaatc acgggaagta ttcactgcta agttgttgcc taaagttacg tcttctgcga
     1861 tgtgacgtcc gccaatctgg gcttttactt tcccggtatt ggtgtcgata agggtggagg
     1921 caacttgcat ctcgtcgtct gggtaagaga catactgatc cgtgttgacg atatcatata
     1981 gtttcttttg ggcgtccaga tccaaattcg tataaatctc taaaccgtct gtgtagacat
     2041 tcttatctgt tttttcttgt acttcattga tgacttcttt gacataatta tcgacgatct
     2101 tagtattgtc atcggattga gttagttctt gcagaccatc cgttaccggt acattaacag
     2161 cttgatcata ttctgtttga gagatttttt cgttttgaag catcgtatac aaaacagtat
     2221 ctcgtctttt cttcgcctga tctggataaa cataaggatc ataggcggaa ggggcttgag
     2281 gcatcccagc aagcaatgct gtttgcggta aagaaagttc tgataatttc ttaccaaagt
     2341 acatctcaga agctgtctcc atcccgtaca agccgtttga catatacact ttatttacgt
     2401 agtaggtcaa gatctcttgt ttcgattttt tttgttccaa tcttacagcc atccacgctt
     2461 cttgggcctt gcgtttcaga gtctgatcct cggcactggt ggagaagaag gaaagtttga
     2521 tcaattgctg tgtcaaagta cttccgcctt gcagtccgcc agaggtaaag ttagagaggg
     2581 cagaaccgat gatccgaata gggtcaaccc cgatgtgttt ataaaaacgg cgatcttcta
     2641 ccgacacgat cgcatcttct aatgttttcg gtaattcatt cgcagaaatt ttttcacgct
     2701 tttctgcgcc taaatcttcg aatagttcgc catcttgtgt atatagtttg gaagatacgg
     2761 tagcgtctaa ttttttatcc gtcaattcgg gcgcatcttt tgcgtaatac cagaaaagtc
     2821 ctacacctgc taaaaagagg atacagaaaa atgagagtat tcctaaaagg atcttgataa
     2881 ataatccttt tttatgtgtt ccagaggact ttccagaacc tttgccagaa ttcttcttca
     2941 cactcttttt aggagtaggc tgtttctgtc gtctagagct tctagtttgt tcatttgcca
     3001 ttcttgcttt ctccttcaat agataatgtt gataaataga agtcaaccgc gtccaaataa
     3061 ggaatccgcg gagaaatacc agttttgatc tctattccta gttcttcgat caaagataaa
     3121 ggtagtgatt tgcgtccttt ttccttttgg gcgtcccagt aagcaatcaa atgaacacta
     3181 ttcaaataaa aacagcgctt caaagacgaa aaccataaca agacaaagca gaccccattt
     3241 tgttcgaggc atgctttcat atgttcgatt tgatgggcat ggaagttttt aaagggaaaa
     3301 gatgttttgt tcttggtttc ttttgcttca aagtccaagt aaaagcctcg atagacgcca
     3361 ttatagtctg tagttgaggc ttgggtaaag taggcttcct tgatcacagc agcacttctc
     3421 ttaggatagt ctactttcac gatttggata ggggtaggct ttttatggat aaccgccaac
     3481 ccgcgggaaa gataatattt attactttca ttgattgctt cttcaaagcg catcccccga
     3541 ttgccgaatt cagtgatctg atttcttttt tcttgaattt tttcgacggg agaggcattc
     3601 ttataataag gttggccatt tggatagcgc aataccatct ttaatcacac tcctaggcca
     3661 cattatagca aaaaagcgga tagaaagaaa aggaatctga gatggataag tcaaaagtaa
     3721 tctatgtgtc tgggtatcga agtttcgaac tcggtgtttt taaagaaaat gatcctaaaa
     3781 tccaagttgt taaaaatgtt ttaaaaaaag aactccatca gttagcagaa gaagggctgg
     3841 aatgggtact tgtcagtggg aatttgggcg tcgaactatg ggctgtgcaa atagtagcgg
     3901 aattgaaaga agaatatccg gaactatctc ttggtatttt gtatcctttt tctgattttg
     3961 gtaataactg gaatgaaggg aaccaagaaa aaaaacaatt agcagaacaa ttagcagatt
     4021 atgtcgaagc tgttagccat caaccctacc aatcacctag tcagctaaag aatcacactc
     4081 gttttatact tgagcataca gtgggctgtc tgctgatcta tgatgaagaa ttccctggaa
     4141 aaacgaagta tttttttgaa gatgcacaga attaccaagc agatcatccc tacgaaattc
     4201 ggctgatcag tatggacgat cttcaaaatt ttagtgaata atcgatattg tgtttgattt
     4261 atcaactttt ttcctataca atgaaaaagg tagaaatgtt attacgtaaa tgaaaactag
     4321 aggtgtaaat atggcgaatt tggtttatag tcctaaagac attttacaac aagaattcaa
     4381 aacaaaaatg cgcggctatg atcccgttga agttgatgaa ttcttagaca atatcatcaa
     4441 agattatgaa gcttacagca aagaactcct tgctttacaa gaagaaaacg atcgattgag
     4501 tgcaaaagta gctcaattat ctaaaactca aggagcagct caaacacgcg tgcaacaaac
     4561 agaggcacca aagagcgcag cagtgaccaa ttttgatatc ttaaaacgct tgtcaaatct
     4621 tgaacgtgaa gtatttggta aaaagcttga tcaacaagca agtgcagtca aaccagcaca
     4681 acctaatcca aataactaca caaatgcaga cacaagctta gatgataatg aaaaaacacg
     4741 tcaattttaa tttttgatta atgaatttgc ggttttcggg taatcgcggt ctgacttgat
     4801 caggctgagg aaagtccatg ctcgcacagg ctgtgatgcc tgtagtgttc gtgcttagcg
     4861 aaaccataag ctaaggtact ctttggagta acggcaggaa aacaagctaa ggcttcggct
     4921 atgcttaagt atccttgaaa gtgccacagt gacgaagcgg ctggggaaac ccatccggtg
     4981 gaacgcggta aacccctcga gcgagcaacc caaacaatgg taggggcgct ttttgtctgg
     5041 aagaagaaca ggacaaaaag gcagtataac tgcagataga tggttaccgc tttgtttttt
     5101 ctccctggaa aagcaaagta cagaacatgg cttatagaaa accgcaaaca tcagggaatt
     5161 aggtcgtgac aaaagtaatg cgttataaga aacaagaaaa acatttgaaa gctatttttc
     5221 aatacttcag atgaatcgtt cttattacaa aacaaacttt tgtatcaccg gttattcgga
     5281 atttgagtaa aagtgtgggg taggactgat gtcccacctc ctttttttat aaataaggag
     5341 attgtgtatg gaaaaaaaca ggaagttcaa cctcgtcgca actgcggcaa gcgggctaga
     5401 agcactggtt ggtaaagaat taagagatct tggaatcgaa tgccaagttg agaacggacg
     5461 tgcacgtttt gaaggaacaa tggaaacgat cgctacagct aatttatggt tacgtacagc
     5521 agatcgagta aaaatcgtgg ttggggaatt cgatgcgtat acgtttgatg aattgtttga
     5581 aaacgtaaaa gcattgcctt gggaagattt tcttccacta gatgcagctt ttcctgtagc
     5641 tggaaaatcg atcaagtcga aactatatag cacacctgat tgccaagcga tcacaaaaaa
     5701 agcaatcgtt gaacgtctcc gtacctatta tcaccgtcca gcttctgtac cactgacgga
     5761 aactggcgca cattttcagt tggaagtagc tttgctgaaa gaccatgtga tggtaactct
     5821 ggatacgaca ggaccaagtt tattcaaacg tggttatcgc ttagaaaaag gtggagcacc
     5881 attgaaagaa aacatggcag cagcacttat tatgttgaca aattggcgaa aagaccgtcc
     5941 attttatgat cctgtatgtg gttcaggtac gctttgtatt gaagcagcct taataggcca
     6001 taatatcgca ccaggattca atcgtgagtt tgcttgcgaa tcttgggatt ggttcagtca
     6061 agaaatcatg gaaaatgttc gatcagcagc cgaagaaaaa gcagattatg atattgaatt
     6121 agatattact ggttcagata tcaatggacg gatgattgaa attgccaaag ccaatgcaga
     6181 agaaatcgga ttaggctctt cgattacctt taagcaacaa gcagtcaaag acttcaaaac
     6241 ggataaagaa tacggggtca tcgtggctaa tccgccttac ggagaacgtc taggagaaga
     6301 agaaactgtt cggaaattat ataaagaaat gggcgatgta ttccgtccat taaaaacatg
     6361 gagtaaatat atcttgacta gcgacttagc gtttgaggaa ttttacggac aaaaagcaac
     6421 caaaaaaaga aaattgtaca atggtgcatt gcgtacggat ctattccagt attggggaac
     6481 tcgtccgcct agaaaaaaag agaaagacga ataatcttac taattgattc attcaattgg
     6541 atgtttggag gaatagggaa tgaaagaaaa agagttttta caagaagtaa aagaaatcaa
     6601 tcttctacaa caagctttag gaatcctcga ttgggataca caaacaggta tgcctgaaaa
     6661 agctagtgca taccgaagtg aagtagacag ctatctttac agcatttatt tttcaaaaaa
     6721 aatcggtcca aaaatcaaag aagccattcg ctatttttct gaacatccgg aagaattgtc
     6781 ggaagttgga actgccgttt ttgccaaagt aaaagaagag tatgatttgg aacatcgcgt
     6841 accggaagat cttatgagaa aatatacagc tgccgtttct tcagcacacg gacaatggca
     6901 aaaagctaga gaaacacaac aattttctga ttttcaacac gcattgaatc aaaatattga
     6961 attaacaaaa cagttgatac cttactggag aaaagatgaa aagacgaatt atgatgtttt
     7021 gctgaatcaa tacgaacccg ggatgactgt cgaaatcctt gataaggtat ttgatcagct
     7081 taaagaagga attctttcga tccgccgtac gctccaagaa aaagggactg aacctgaaac
     7141 agacttttta aatcggagaa tgacgaaaaa acaacagaag agatttgtag tgaaagtaat
     7201 cgaacaactt ggttatgatt ttagtcgtgg tcgtttagat gacactgtcc acccatttat
     7261 gactggaatt aatccgaatg atgcacgaat cacgacacga tggaacgaaa cagatttcaa
     7321 aatggctgtt tttggagtga tccacgaggc tggtcatggt atgtatgaac aagacatcga
     7381 tgataaatat gcgtatacac cggtttatga aggtacatca atgggtatcc atgaatcaca
     7441 atcgttgttt aacgagatca ttattggaag tagtcgcagc ttctggaaaa agcaatatcc
     7501 tttctttcaa gaatgtgcag aaggaacatt cgatgatatt ccttttgaca aattttatcg
     7561 ttcattgaac catacaaaat caagtttggt tcgtatcgag gcagacagtt tgacttaccc
     7621 tctccatatc atcattcgtt atgaaatcga aaaaatgatt ttcaatgaag gggtagatgt
     7681 tgctgaacta cctgaaatat ggaatcaaaa atatgaagag tatctgggaa tacgaccaac
     7741 aaatgatgtg gaaggcatcc tacaagacgt tcattggtca ggtgcaagct ttggttattt
     7801 tccctcttat gcattagggt acatgtatgc ggcacaatta cttcattctt tgcagcaaga
     7861 aatagatgtg gaaaatgttc tagcgtcaga cgattattct ccaatcaaaa actggatgtc
     7921 agagcatatc catcaatatg gtgcatctag aaaaccaaat caattaatca tggatgcaac
     7981 acatgaaccg cttaatccgc aatacctgat cgactatatg aaagacctgt attttaatgt
     8041 atatcaggta aaataaaata caatttacaa agatagctga aattcatcta atctatagat
     8101 gttttcagct atttacttaa gaaagaagtg gaacgaatgg ataaattaca agtgatcgct
     8161 gattatagta tggaccaatt agcgcatgat caaacaggac atgggagcga tcataccaaa
     8221 agagttgtca agttagctga aaaaattttg gagacggaac cgcaggcaga ccgctttgtg
     8281 acgcttgcag cagcttacct acatgatacg attgatgata aagtcgttaa aaatgagaac
     8341 gaggcaaagc aacagcttcg tgtattcctt cgctctttgc caatagtaga ggaacagatc
     8401 tcgatgattt tttccattat cgaaaatatg tccttttcta aaaatctctc tgaagcggcc
     8461 gaactatctc tggaaggtaa gatcgttcaa gacgctgatc gtatcgaagc attaggagca
     8521 atcggcattt tgcgtactgc ttatttcggc ggtggacatg ggcacccgat ttttgatcct
     8581 gaactgtatc cgcaaacatt caaggacaaa gaaaattacc gaaaaggcac gacagtgatc
     8641 aatcattttt atgaaaaact gttcttgctg tctgataaaa tgaatactga ttacggatat
     8701 gaagaagcca aacgaagaga aaccttcatg cgtgaattct tagaagaatt ttttctggaa
     8761 tggtctattg acgatgaaaa ttttactcca gacaattgga tcaaaaataa caaaaaatga
     8821 tggaggttgt gacagaagtg gtcagctcca agatatttcg gatcattttc cgtaaaagtt
     8881 acttctggaa cactgtttac caagaggtcg tgagcctgcc gttcagctcc gagtcacaag
     8941 gaacaatttc aaaaaatagc ttctcgtgtt tgatgaatat tgtaacttgt gattcggaat
     9001 tggcaggaga acaccgttta ttcggaagaa taggactgtg acaagacttt tgtcacagtc
     9061 cttttttcga attcaacaag taaaactttt aagaaatatt cagagagtaa aattaaaaat
     9121 tgctgataaa cgaagatgga aattttatgt atttttattg gtctatgcaa taaa
//
LOCUS       DACGDM010000098         9048 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.104, whole genome shotgun sequence.
ACCESSION   DACGDM010000098 DACGDM010000000
VERSION     DACGDM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.104"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="IXR05_002391"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="IXR05_002391"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAQ4260865.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            2714..2938
                     /locus_tag="IXR05_002392"
     CDS             2714..2938
                     /locus_tag="IXR05_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260866.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            2951..3451
                     /locus_tag="IXR05_002393"
     CDS             2951..3451
                     /locus_tag="IXR05_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4260867.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            3548..5395
                     /locus_tag="IXR05_002394"
     CDS             3548..5395
                     /locus_tag="IXR05_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAQ4260868.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            5398..6294
                     /locus_tag="IXR05_002395"
     CDS             5398..6294
                     /locus_tag="IXR05_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4260869.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            6344..6733
                     /locus_tag="IXR05_002396"
     CDS             6344..6733
                     /locus_tag="IXR05_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4260870.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            6720..>9048
                     /locus_tag="IXR05_002397"
     CDS             6720..>9048
                     /locus_tag="IXR05_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4260871.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         3196 a         1362 c         1909 g         2581 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatatat caatggtttt taaccaatgc
     2761 tcaatcttta gtcttactag cgattgtggt cattggtttg tttttaggat ttaaacgcga
     2821 gttttccaaa ctgattggct tcttggtgat tgctttgatt gcggtaggtc tggtctttaa
     2881 tgcttctggt gtgaaggatg tcttactcaa tttgtttaac cgaattgtcg gtgcctgagg
     2941 gggaatcaca atggaacaga tacgtgttta tattgcgaac cttggaaaat acaatgaagg
     3001 tgagttggtg ggggcatggt ttaccccacc cgtcgatttt gatgaagtga aagaacggat
     3061 tggattaaat gacgaatatg aagagtacgc aattcatgat tatgaactgc cttttgagat
     3121 tgatgagtat acaccaattg aggaaattaa tcggttgtgt ggtttagcgg aagagcttaa
     3181 aggaacgcca attggtgagg tcgcttcaga gattcaacat gccttcttca attctttcga
     3241 ggaaatggta gagcatgtgg atgatatcat ctattatccc gattgtaatg acatgagtga
     3301 tgtagcgtat tacttgattg tagaagctgg tgatttaggc gaagtaccag aacacttgaa
     3361 gacgtatatt gattttgatg cgtgtggtcg agacttggag attggcggga attatttggt
     3421 tacgagtcga ggggtttttg aactaatgta aatcatttgt tagaattgac cagaaatttc
     3481 tatcgtactt ttacttttct atttgatata ctgaaataga aaatatttgt tgataggggt
     3541 gttactaatg gttggcaata agtggtacaa atgtgatctt catattcatt caactgcgag
     3601 tcagtgcttt caggataaaa aggttactgc taaggaatgg gtagaagaat gtttaaacaa
     3661 aggactcgat tgtgttgcat taactgatca caatacaggg gaaaatattg atgaatataa
     3721 gaaagtggct atcgaaaatg gcttagattt ttttcctgga gtggaattaa cgtgtggaga
     3781 aaatggaact catttactag tcctatttga taaaagtgca tgtacaaatg atatctctga
     3841 tttcttaacc aagatgggta taaaaagaga ggattgggcc agcgctgcag cttgctcaat
     3901 gaaatcagtt ttagaagtta ttgattttgc tgagcacgag ggcttgctcg ttattcctgc
     3961 acatatagat gagtttaatg gaatttcttc agcaaaattt ggaaatctag gaaagatatt
     4021 tgaatcagaa aatatatatg cagtacagac ggttcaaaaa gaattttttg aaaatcgctc
     4081 acaaatgatt ccctcatcta agcgtgacac tatctatgat agtgtgaatg ccagatatga
     4141 tggtagagtt ggaaaagata ctttggaatc ttggtataaa tcagttgttg aggcagaaaa
     4201 aaataatatg acatttctta gcttttctga taacccacac tcgaaaggaa attcaaaaca
     4261 tggactttgg ggaataggca caagatattc ctatataaaa atgaaggacg aacctgactt
     4321 gggatcactt cgcgatgctt taatgctagg cgaaactcga gttcattctg atttttctaa
     4381 tttctccatt aatgaaaatg aagttttatt ggaaaaatta agcttttctg ggaccactct
     4441 tagcacaaaa gaagttgtag tcgaattcag cgataattta acttcaatta ttggaggaag
     4501 aggaacaggc aaatcttgta ttacaagatt cttggtctat gtccttggaa aggaagcaga
     4561 acttgatcaa ttttctgaaa tacaaagtga ttatcagaac tttgcacaaa ttgaacataa
     4621 tggctctgga atatttttga aggatacaat tgtgaaactg aatattttct ataaggggac
     4681 aaaatatcaa ataataagaa cacaggatag acattctatt tatgaattta cacaagagaa
     4741 tggtctggtt gaaaaagaaa cagaacggtt gagaatgatt tccgataagg tgagtatata
     4801 ctctcaaaaa caaatttatg aaatttcaaa aaatcaaact agtatactag aattactaga
     4861 tggatataac tctgatttga tttcagagta taaaaatgag attgaaacat gtgtaaacga
     4921 aataagaaaa ttaaattggg atattgtttc tgtgaaaaaa gaaatacaag ataaggcgaa
     4981 ggtagagctt gaaattgaag atttaaaaaa acaagtagaa aagctatctc ataagagtta
     5041 taaagatgtt tatgatgagt attcaaaaga gacagatatt tatagggaac tgaaacgtga
     5101 tgtggaggca cttaaggaaa ttcccaaaaa tctaactgat agtgttgaca aaattgactt
     5161 tggcaatggt ataaaagtta cagacgaaat tgatgaacac cgcggagaat tgattaagaa
     5221 tttagtgacc aatcgggcta agattcaaac aataattaat gaaatgtcag atgaaattga
     5281 tagttataga gcagagctga ataaatcaga ttggaaagtt aactataatg aggtttcaaa
     5341 gaggtatcaa agaggtatca aaaacttagt gaagagttat ctcaagatga attaaaaatg
     5401 ttacaaaacc ttgattcttt atatcaatct ttatcaaaaa ctgaagagcg attggaagaa
     5461 attattcaac aagaaataaa gcttaaagat taccaagttg aggttgactc agcaatgtca
     5521 agaatgaata aatcatatca aaatctctat tctgagagaa gtagttcctc gcgcgaaatt
     5581 ttttctgata ttacaggaat agaggctact attcaaccaa atagggattt caataattat
     5641 gttaaagagc tcagagcttg tattaataag gaggacactt ttgacagtga gtttggatct
     5701 cttattgata agctgacaaa aaattccatt actaatcaag atatatataa tgacatactt
     5761 gatataagag ttagtgggga aagtagtatt ttttcagata aaaaattaat caattctata
     5821 agaaaattga atgatgcaca agttcttgaa ttacaaaccc ttaagccaaa tgatttagta
     5881 gttatccgac ttgaactaaa tggaaaaaaa gttagtttat cgaatgctag tgctggtcaa
     5941 aagacatctg caattctttc tatgattttg gcgtatggaa attcaccact catattggat
     6001 cagcctgaag atgatttgga tagtcaatta attaataact taatcgtaag aagtatcatt
     6061 acaaaaaagg aaaacagaca aattttaatt gtaactcata atgcaaatat cccagttaat
     6121 ggtgattcag aatggttgat tagcatggga gattcaaaag aaatatcggc tgatcagtgc
     6181 gggtcggtag atgaacccaa tatcaagcca agaatatgta ctgtgatgga aggtggcgag
     6241 gatgctttta caaatagagc gaaacgctat ggttttaaac aaattgtaga ataacactag
     6301 agggtgagac atattattat gtccgccctt tttaggagga aaaatgaaaa aaataaaaag
     6361 ctataccagt atctgggcag ttgaaaaagt catttacgca atcaatgatt ttcagttgcc
     6421 ttttcctgtg acttttaacc aaatggcttg gttcgtttta tctttactgt ttgtcatcgt
     6481 atttgcccat gtgcctccac tatctatgat agaggaggtc tttttaaaat acttaggcat
     6541 accggtggct gtcacttggt ttatgtcgca aaagacgttt gatggcaaga aaccactggg
     6601 atttttacga tcctttatca gctatcactt gcgatttaag gtgacttttg caggaaagaa
     6661 agtcaaagaa cagaagaaac gatgggatga acccagtact cttgtaagga gtgtgaacta
     6721 tgtatccgat taagtatatt gaaaataatc tcgtctttaa ccaagaaggc gagtgttttg
     6781 cctactatga attagtgcct tacaattact cctttttgtc acccgaacag aaatttcaag
     6841 tgcatgataa ctttcgccaa ctaattgcgc aaaatcgtga aggcaagatc catgcgttac
     6901 aaattgccac agaaagtagt attcgcgcca cacaagaacg atcaaaaaaa gaaattaccg
     6961 gtagactcaa agaagtagcg aaacaacgaa ttgatataca gacagatgca ttagtatcca
     7021 tgattggcga tagtcagatt gattatcgct tttttattgg ctttaaacta attgcgacag
     7081 atgaagaagt caatctaaag agtctcaaga aatctttctt ttctgggctt caagaatttg
     7141 tctatggagt gaatcatcat ttgatgggcg attttgtttc cttatccaat gaagaaattc
     7201 gctgctattc taagcttgaa aaattaatgg aaagcaaatt ggctcgaaga tttaaagtca
     7261 ggcgagtcac accgagtgac ctgacgtatt tgattgaaca tatttatggc gaaaaaggga
     7321 taccgtttga agaatacgaa tttcagctac caaagaaaaa gctaaaatca gaaacactgg
     7381 tgaaacgtta tgacttatta cgtccaaatc gttgtttaat tgaagaaaaa ccaaggtgct
     7441 tacggatgga acatgagaat catgagtcgt acgtagcgta tttaacaatt aatacaattg
     7501 tgggggagat ggaatttcct tcctcagaac ttttctatta ccagcaacaa caatttacat
     7561 tcccaatcga cacaagtatg aatgtagaga ttgtgacgaa taaaaaggct ttagctaccg
     7621 ttcgtaataa gaaaaaagaa ctgaaagatt tagacaatca tgcttaccaa tctgacaatg
     7681 aaacgaattc caatgtctta gatgctttgg attccgtgga tgaattggaa accaccttgg
     7741 atcagtcaaa agaatctatg tacaaactga gttatgtggt tcgagtgagt gccgaatcag
     7801 tggatgaact aaagcgacgc tgtgatgaag tgctcgattt ttatgatgat accaatgtaa
     7861 aactagtccg gccctttggc gatatgatgg ggctacatga agaattctta ccctcaagta
     7921 aacgatatat gaacgactat attcagtatg ttacgtctga ttttttggcg gggcttggtt
     7981 ttggggctac tcagatgcta ggagaattag aagggattta ctttggctac aatgtggata
     8041 caggtcgtaa tgtttacctg aaaccggcat tggcttcaca aggagtcaag ggttcagtaa
     8101 ccaatgcgct ggccgccgct ttcctgggtt ctcttggtgg aggtaaatcc tttagtaaca
     8161 atctcttagt ctactatgct gttttgttcg gtggtcaagc tgtgattgtc gatccaaaag
     8221 gggagcgagg agggtggaaa gaaaccttgc cagaaattgc ggatgaaatc agtatcctca
     8281 acttgacgag taagtcagaa aatcaaggtc tgcttgatcc ttatgtgatt atgaagaaaa
     8341 agaaagactc ggaaagttta gcaattgata ttctgacttt tttaacagga atttcaagtc
     8401 gagacgggga gaagtttcct gtgttacgta aagccattcg aacggtgact caaagtgatc
     8461 aacgggggtt attacaagtt attaacgaat tgcgaaaaga cgggtcacca atcgcggaaa
     8521 atatcgccga tcatatcgag tcctttaccg attatgattt tgctcatttg cttttctcag
     8581 acggctcgat tacccaatcg attagtttag ataaacagct aaatatcatt caagtggcgg
     8641 atttggtttt accggatgca gaaacgactt ttgaagaata taccaccatg gaattgctta
     8701 gtgtttcgat gctaatcgtc atttccactt ttgccttgga ctttatccat agtaaccgag
     8761 aaatcttcaa aattgtcgat ttggatgagg cttggagttt tcttcaagtg gctcaaggaa
     8821 aaacgttatc gaataagctt gttcgtgctg gtcgggccat gaatgctggg gtctatttcg
     8881 tcactcaaaa tagcgacgat ttattagatg aacgtttaaa aaataatatc gggttgaagt
     8941 ttgcttttcg cagtaccgat attcatgaaa tcaagaaaac cttggaattc tttggtttgg
     9001 atcaggagga tcaaagcaat caaaaacgcc tgcgagattt ggaaaacg
//
LOCUS       DACGDM010000099         8999 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.105, whole genome shotgun sequence.
ACCESSION   DACGDM010000099 DACGDM010000000
VERSION     DACGDM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.105"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            211..1425
                     /locus_tag="IXR05_002398"
                     /pseudo
     CDS             211..1425
                     /locus_tag="IXR05_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1604..1939)
                     /locus_tag="IXR05_002399"
     CDS             complement(1604..1939)
                     /locus_tag="IXR05_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4260872.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1923..2195)
                     /locus_tag="IXR05_002400"
     CDS             complement(1923..2195)
                     /locus_tag="IXR05_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAQ4260873.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2646..3449)
                     /locus_tag="IXR05_002401"
     CDS             complement(2646..3449)
                     /locus_tag="IXR05_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAQ4260874.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3427..4551)
                     /locus_tag="IXR05_002402"
     CDS             complement(3427..4551)
                     /locus_tag="IXR05_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4260875.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4567..5382)
                     /locus_tag="IXR05_002403"
     CDS             complement(4567..5382)
                     /locus_tag="IXR05_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4260876.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5372..6253)
                     /locus_tag="IXR05_002404"
     CDS             complement(5372..6253)
                     /locus_tag="IXR05_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4260877.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(6329..7618)
                     /locus_tag="IXR05_002405"
     CDS             complement(6329..7618)
                     /locus_tag="IXR05_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4260878.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7846..8490)
                     /locus_tag="IXR05_002406"
                     /pseudo
     CDS             complement(7846..8490)
                     /locus_tag="IXR05_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2792 a         1906 c         1439 g         2862 t
ORIGIN      
        1 gattatccat tgagagactc ctttggtagg atgacgtttt ggtcgactaa attttaccaa
       61 aagtgagtct ctttttgagt tgaaacgaag aaaaagtgtt agtagaaaat cgccttcgat
      121 tttccaccaa cacaaaatat tatagaagca aaatcaattc taccttagat gttcttatat
      181 cactctatca gtcctatttg acaaagagcc aagaaaaaga cgttggtcgt cgatgctgtt
      241 ctctcgccta ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga tggaaacggg
      301 aaagcaatta tagtgaaaaa tgggaagaag gaaacgattg tccgttttga acaatacaat
      361 catatgcctt tggttacgcg cctaaaaaag caacgctata cctgtaaaaa ctgtcgtacc
      421 cattggacgg ctcaaagtta ttttgtccga ctcagccatt caatcgcaga tcatgttcga
      481 tataaaattg cttctttact gactgaaaaa gtatctttgt cttttattgc gaaaagttgt
      541 caggtatctt tgactaccgt tactcgtaca ttgaaagagt ttaaaagcta tttaccaaag
      601 ccttctaaga agattctccc cagagtattg atggttgatg aatttcgttc gcacgcttcc
      661 atagaagata aaatgagctt tatttgcgca gatggtgaaa caggaaactt aattgctgtc
      721 ttgcctacgc gtaaattacc tcgattaaca agctatttct taggctgcac caatccagaa
      781 gaagtagaat tcttagtcac agacatgaac gccgcttact tccagcttac caaacgtgtt
      841 ctgccaaatg cgaaagtagt gattgatcgg tttcatattg tcaaacacat gaatcaggca
      901 ctcaatgagt tgcgtatccg tgaaatgaat gagcttcgta aagcaggaca gaaaagtcag
      961 gcagaaaaac tgaaaaagaa ctggcgcttt ctgctaaaaa atcgtgcaag catcaaccat
     1021 tatgagtaca aaacatggaa aagtttccga gcaccaaaat acccatttct cactgaagca
     1081 atgatgattg atcgattgct tgagttttct gcgcctctaa aggaggcgta tccctttttt
     1141 catgaattag tcgaagcctt tcgagacaaa gaccctgact tatttttctc cttattggca
     1201 gaacttcccg aaacgttaga tgacggcttt cgggagaagc ttcaaaacct tctgacctat
     1261 gaagaaggta tcaccagcgc aatgatctat ccttattcca atggaaaaat tgaagcgaag
     1321 aatacccaca taaagacaat gaaacgagta tcctacggat ttaaatcatt cgagaacatg
     1381 agaattagaa tctttttgat caatcaatta atcaatgtaa gataacaaaa aatctgaacc
     1441 agaatgtggt tcattctgac ccggatttga ttttgcacaa ctcatcagtc cttattgaca
     1501 aagagccaaa aatctgagcc agaatgaggt tcattctgac ccagatttga ttttgtacaa
     1561 cccatcagtc cttattgaca aagagccctt ctttttagta ttattataat tcttccatgc
     1621 gttcttccag tcgctgtaaa tcgcttggac ttaattcccc aatttttttc catttgacct
     1681 ttttgttgtt tttgggtaat tcgtttagag ttcctacgtc aatccaagat tcttttttta
     1741 gtcctgcctg tttccaatcc cttatttcaa cgtatttcag ctttatttta tcggatttag
     1801 tatgatattt tgaagtaatt gacagaaacg aaattgtgtc cagtccattt tttagaatat
     1861 agacaggccg gcgtttaccg ccctctgcag ctgtgaaagc aacgtagacg gttgctatat
     1921 cattagtatt catcttcatt gaaccattct tcaatttttt cgtcagtgtc tagtttttgg
     1981 acaggcaatt tttccgctaa tctttgaata ttatggattc gtttactttt ttccgacaat
     2041 tcaatagaaa atgggatttt tccttgctca acaatttgct tataaaaaac ggtgacggct
     2101 gttttggggc tcatgcctag ttcatcaata atgctttctg cttcattttt caatttttcg
     2161 tccatagaaa tttgtaactt agccattttc tccacctctt tctgacaaac acattatatc
     2221 acggaaagag ttcaaatgga attaatacaa ctacttttga actccttgaa atgcagtgta
     2281 tttatctaaa tataaggaaa ggatatagtg ctaaatggcc ttgatagata gaaaagtttc
     2341 aaaatccgcc acagcgataa ttgaagcgaa cactcaacga cacacagaac aggaaaagac
     2401 tcctaaaaga accaaattaa ctaggacgtg tctgaaaact ccacaaagat gtggtatgct
     2461 ctggtaaaaa acgaatggca caaccacgaa gaccgatatg gttcttggaa aactttctcc
     2521 accctttttg taattggagg gatagtggtt tattgatagc gattttccaa gttcttcaag
     2581 tggaaccaga cattgagcac cacggctaaa aagtgaatga agtctttatt tttaatcaat
     2641 aatttttaat gattaccagt aattggtttt ttcatgcgcc ctatttctat ttgatgtgga
     2701 gttaaataat gctgataagt aaaaattttt ccgtcaatta aactgccact agtgaatcct
     2761 gttctattgg taaaaagaga atagtctggg tattcatcta caccaaatga taaagattca
     2821 gccataaact gttttttacc agcaaattca gcactgctac cttgatggat atgtcctaca
     2881 aaaataccta aaatatcact ttcggcaatc aattcagcaa aaccttccgg aacttcagtt
     2941 acaatagatg gatcttccca cgacaatgga tgatgaacca ataaaatcgt tcccttttca
     3001 gcaggtgtac ccaaccactc ttgtaattga atcatctgtc ctatcgatat ttttccttcg
     3061 tgctgggtat cttgagcaga atccaaggaa ataattcgta acccattttg attcgtacaa
     3121 tggatatact ctcccgtttc attgctttca acactcattc cttcaaagaa aacactgcga
     3181 cgatcatgat tcccacgaca aaaatagtaa ggtgtggttg ggaaatattg atccaacatt
     3241 ttccgtaaga cttgataatc agaaatcccc ccttcatgta ctaaatcacc tgttaataga
     3301 ataaaatcgt acactgttaa cgagagttct tgtaacaatt tttccaatgc caactgtgga
     3361 tttttaattg ttggaaatag ttcagcagta aacaagttag tttgatagtt ttctctaaaa
     3421 tggatatcag agagatgcaa aaagcgcatg gctattccct ctttcttcaa taaaataatc
     3481 aggatatcct aaattttctt gcgtctgata atcaaaaaaa tgcattcttt caggttctat
     3541 gcggagattg actgcatcac caatctgcca agtaggtttt tcattaagga caatcatttc
     3601 tataccatcg actttaacgg tgtacgcata actttgacct aatagctcac gatacttcac
     3661 ttgaccgtgt aaatcgcttg tttcttttga aaaggttacg tgttctggtc ttatgcctaa
     3721 atacaatgag ccactaacct gaagaagttg tttttgccaa gctggattca atgttaaaaa
     3781 ttgactggct acctttaatg ttccttgatc ataagtaact ggcataatat tcatgcctgg
     3841 cgaaccaata aaatttgcag taaaagtatt tttaggtttc gtataaacat ttttcggcgt
     3901 atcaatcatc tgaattctac cttcattcaa taaaacaatc cggtcagcta acgtcatcgc
     3961 ttcaatttga tcatgagtga cgtagacaaa agtttgttta taacgttgat gaatttttac
     4021 caattctttt cgtgcatcca atcgtaaacg cacatccaaa tttgataacg gttcatctaa
     4081 taaaaaataa ttactccgtt taaccaccgc acgagccaat gctacacgct gccgttgccc
     4141 tcctgacaaa tctttaggaa gtcgatcttg gtatggcgtt aaacctaaca tcttcaaagc
     4201 ttcttccaaa cggtgctgaa tgtcagctgt cttaatttta ttcgccctta atgcaaaaat
     4261 aatattctcc tttacagtca tgtgaggata taaagcataa ttttgaaaaa ccattgcgat
     4321 ctctcgttct ccacaaggta gcttatttgc tagttgtgta cctaaaaaaa gctctccact
     4381 cgtaattttt tccaaaccag caatcattct cagcaaagta gattttcctg aaccagatgg
     4441 tcccagtaac acaattcgtt ctccagcggc cacagctaaa tcaatttctt ttaaaatggt
     4501 atgttctcca tatttttttc cgatatttct taattcaagc gtttctccca tgatttgtcc
     4561 tccaatttat ttaatacctg cagaaacaaa agtcccgata atatattttt gaaaaattgc
     4621 atacaagact aacggtacaa acattgtaat taaactaatc gccattgcta cggtaaaatt
     4681 tgtcccacct tcagaactaa tataggtctg catcgccaac ggcaaagtat aattatctac
     4741 tgtccgtaaa attaataccg gccaaacata ctcattccaa gaggtaataa aaaaccaaat
     4801 accggtagaa gtaatcgcat gtctagtaag aggaaaaaca attttactca tgacggttgt
     4861 ttgtttgatg ttatccaatg ccgccacatc tagaaggctc actggaattt cccgcattgt
     4921 ttgcgtcaat aaaaaaatgc ccatcgcatc agcaaattgt ggtattatca caccccaagt
     4981 agtatcaatt aaattaagtt ttgcaatcaa caaataatta ggaatcatcg caacagtaaa
     5041 aggaatgaac atcgtaccaa tgatgataaa gtaccagatt ttcttccctt tgattcggca
     5101 ataagtaaaa ctatatgccg caaaaaaagc tacgcctaac ttaacaaccg ttataattgt
     5161 agcaataaaa aaagtatttc tcgtaatttt gataattgga agattttcga acaaatagca
     5221 aaaattttcc aaggtaaacg gctgtggtat caaactagta atcgtctgat aggcatcttt
     5281 caatggctta aaagaattgg ccataataaa caataatgga tagataataa tgattatgat
     5341 gaacataaat aagagatgtg gcaaccagcg tttaattttc atagtaaacc cccttttcca
     5401 caaatttaaa tattacccct aagaaaacag caaatattaa taaagttaaa actgaaattg
     5461 ctgaagattc tccgacttta tacatttcaa aagccttttg ataagcataa tagatcacgt
     5521 ttgcactacc attattcggt ccaccacgag tgatgatctt aatcggagta aacacatact
     5581 gcagaccttg aacaatggtc atcaccaata aatatagtcc tgtcgaacta ctcataggca
     5641 acacaattgt aaaaaaaatg cgccagatgg gtacacgatc caacttagct gcttcgatca
     5701 tctcttgatc aattcccaca attgctgcaa aaatgacaat gaaattataa ccaaaaactt
     5761 tccaagcagt aatacctgca atcacagcaa ttacccaacc ttgtaaattc atccacatag
     5821 gcagtcttaa accaaaattt cccaacaaga cagcaattgg tcccgatacc ggatttaata
     5881 tccatgtaaa aaccatcccc gccactacca aagaaatcac agctggaata aaaaataatg
     5941 gtttatacaa attctgccct ttttctataa ctattcctaa taaaaaggat gtaatatatg
     6001 ggaacacaca gctcagcaag acaaatagaa cggtatagga caaagtattc ttcaacactt
     6061 tatgaaagac tggatcagtc agcaccttta catagttggc aaagccaaca aattctttag
     6121 tgggggccac catattccag tcaaaaaaac tcaaatagat cgtataaatc aatggataaa
     6181 aaacaaacac gcccaacaaa ataattgctg gcgccagata caaataacct acatagcgct
     6241 tcatttccga cagcctcctc atccttatgt caaaagcaga cgaccttgtt tttcctttct
     6301 tacaggcgct gtcgtctgct tgctttgctt atttgagtaa ctcattaatt tccttttgag
     6361 tagctttcat cgtttcattg acggaattac ctgataaaat tttatcccgc atatccaaca
     6421 atttttgttc agcttctaat ccagcatctc caggaaatga actccaactg accatcttat
     6481 ccatctgatc aattgctggt atcatcatct gattttcagc taagaaagct tttaatccat
     6541 tttgggcgtc tgcaacatct ttacgtggtg gtaaataacc agtaccttct gtccatttag
     6601 ctaaagattc aacactataa agatatttta agaaatccca agttgcttcc tttttcttat
     6661 ccgtttgtga tgtaacagct aacattgcgc caccagcagg tagtttaact tttttccctt
     6721 cccaacttgg tgactcaact gctttagcag taaaagtact atttttttga atgttgtccc
     6781 tttgagcaat agtggtatag accatcgcga cgttaccatc aataaagctt tgcacacctt
     6841 gttcccacgt agtgtgtaat gccgtctggt cttttaccat cctttgatat aattcataag
     6901 cagcgatacc atctttagaa gcaaaggtag ctttgccatc ttttattaca cttgccccat
     6961 tactttctaa aattgcttgt tgtgcccaat tatcagcagg ttcttgaata tacacgccat
     7021 actttccagt tttttctttt attatcttag aaaaagtttg aacttcttcc caagtttttg
     7081 gaccattttc atccaagccc gctgctttta atatatcttg atttaaatat aaaaccggat
     7141 tactaatgga gtaaggaata cccacttgtt taccatcttt ttcagacagt gccatgatat
     7201 tgtctaaaaa atgatcttta aaataatcag cattatccgg atccacttct tctactaaag
     7261 attgaggatt agtatatttg aaattttctg caaaataatc tttaaaagcc catcccactt
     7321 gtactacgtc cggtatttct ttggaggcaa cagaagcttg taaattttgc atcaagcctt
     7381 tatacatatc aggattatat tttgctacaa ccttcacttt gtcttgagat tgattgtatt
     7441 tatctactaa ttcattcact gtttttccac ctagggtatc cgcattaaca tgccaatact
     7501 ctatcgttac acgaccctcc gatttttttg ttgtcttggt attcccacta ccacaagctg
     7561 ccaaagagat gacacttaaa acagacacaa cccctataac aagatttttc tttaacataa
     7621 cattaacttc ctcctaattt ctttatggcc atttttctaa tcaagaaata ttatgaacta
     7681 ccaatgtaaa tttctagtta attttctgta aataattcga aatttgtgca tttcggggta
     7741 cagggtcact ggacatatcc atcaagctaa gaataaagcc cccatatggt catgtatccc
     7801 atctccaaat ctcttaactc ctctgttttg attataaaat agtttattct gtgctccttt
     7861 cttccataaa taggcccatg cacaacgtga ggttatatta taaacaccac agcgcgcaag
     7921 gtactcaatc gtttctagtt cattgactgt ccatacagaa aatgtcaatc ctagctgctg
     7981 ccccacttca cgggccaact tagttaacca tccttcatga atattgacga tttgaacgct
     8041 ttgataggct aatttctgta aggtatcgat caaatctgct tcggtaatat ccccaagttt
     8101 tttcccttcg aactgatttt caatattata aaatatatgc tttccccaaa tcgcagccca
     8161 agataattgt acatagccac taagaacaat ttgtggccag atttgatagg tttgtgccag
     8221 cgaaaaaacg gccatttcca atccctcttc ttttaaatca cagttaatgg tcatggttgc
     8281 cttctcattg gccactgctt gaaacacctg ctcaagggtt accgaatctg ggacaacttc
     8341 ttacctgtca tgggctagta ttagcgtacc atctgtttgc tgacgcacat ctacttcaaa
     8401 acaaagctgg cgatccaaac aaaagcgaag aaatgcccag ctattctcct ccgtattgtc
     8461 actaccagag tgtgcagtga tcatggtcat tttgacccct cctttaattc cgtgattttc
     8521 tcccacacgt ccactatacc gatgaagcgt taatttcttg ttaatttctt gtaaattccc
     8581 tgcgtttttt cagtaaacta gttgtaaatc ttgcatgctc cttcctacga actcatgaat
     8641 cgtcgatttt gcccttctag ctagtttcac caattaagta gttctacatt ccccgctttt
     8701 aacctactac accttttttt gttttcagct attccttctt cttgctgaaa gtccttgagg
     8761 ttctttctta caggatacca tcaaggtgtt caatggctta ttcccattga atgaccgaga
     8821 cttactatca gatttctgct cgttgaacca agtctttgat acaggatttc ttccgtcatc
     8881 ttctcacaaa taccaccttg cgtttctcta gcgattggtc gatgtgcacc ctcccagtgg
     8941 actgtcacta cccctttttg ctatgcctag cccacaaaaa aagctgtcct cacagacag
//
LOCUS       DACGDM010000100         8937 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.106, whole genome shotgun sequence.
ACCESSION   DACGDM010000100 DACGDM010000000
VERSION     DACGDM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.106"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(431..928)
                     /locus_tag="IXR05_002407"
     CDS             complement(431..928)
                     /locus_tag="IXR05_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4260879.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(968..1777)
                     /locus_tag="IXR05_002408"
     CDS             complement(968..1777)
                     /locus_tag="IXR05_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4260880.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2111..2968
                     /locus_tag="IXR05_002409"
     CDS             2111..2968
                     /locus_tag="IXR05_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4260881.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            2961..3863
                     /locus_tag="IXR05_002410"
     CDS             2961..3863
                     /locus_tag="IXR05_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4260882.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3896..4246
                     /locus_tag="IXR05_002411"
     CDS             3896..4246
                     /locus_tag="IXR05_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4260883.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4280..5217
                     /locus_tag="IXR05_002412"
                     /pseudo
     CDS             4280..5217
                     /locus_tag="IXR05_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            5295..6188
                     /locus_tag="IXR05_002413"
     CDS             5295..6188
                     /locus_tag="IXR05_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4260884.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6226..6789
                     /gene="amaP"
                     /locus_tag="IXR05_002414"
     CDS             6226..6789
                     /gene="amaP"
                     /locus_tag="IXR05_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4260885.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6803..6991
                     /locus_tag="IXR05_002415"
     CDS             6803..6991
                     /locus_tag="IXR05_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4260886.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            7004..7906
                     /locus_tag="IXR05_002416"
     CDS             7004..7906
                     /locus_tag="IXR05_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4260887.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7938..8180
                     /locus_tag="IXR05_002417"
     CDS             7938..8180
                     /locus_tag="IXR05_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4260888.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8436..8807)
                     /locus_tag="IXR05_002418"
     CDS             complement(8436..8807)
                     /locus_tag="IXR05_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260889.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3111 a         1548 c         1732 g         2546 t
ORIGIN      
        1 acggctcata accgtccggt cgtaggttcg agtcctacaa ggtacataag aggttgtgaa
       61 aaagctgccc tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta
      121 cttggctgtt cttattactg cagatgcaag cttttgaata ccgtttaagg aagaggttgt
      181 gaaatcagcg ttttgacctg agtattagct taacaaacgg aaaaatagtt cctcatattt
      241 tgccgtttgt taagctaata ccgagggtca gctgattgaa caccatttaa gaaagaggtc
      301 gtgagcctgc cgtttcactc tgtgtcataa aaaagccaat ctactttgat agaaaaagca
      361 cgtaggacta aaacagttct gcgtgctttt tttattgtgt gttaaatatc gtaaatgaag
      421 atagatattt ttatgattcg acgatagaga cgttgaaatc tttcaacagc tctaaagcgg
      481 attctccgtg ttttctactg gagactaaca ttggatcaac aaaaaagtct gcttcaggaa
      541 aagcactctg caggcctatc agattagaga gtacacacaa gtttgtttca atcccgacta
      601 cttcgatctc tttttgttct tctttgcttt caaataaagt ttcctggatt tcagctaaag
      661 tttcaggtgg aatcgtaaag taatactttt taatcactcg ttcattttct tgtggagaaa
      721 gaagagggat caattgcaaa tcttctcgtt cttcttcttt gtccttcagt tcaactggta
      781 tatcccgtgt gaagagaata tattcattat tttggcgtgc tttagctaat ctttgagcaa
      841 tacgttctgc caattgatct gactctggaa tataaaattc gctgtttgga tcaagaatat
      901 gattttgcat atcaataata actaacattt tctttcctcc tacattcata tcgtcatttt
      961 attcttttta atagaagttt tttaaaatat aagcaacacc agcttcttca ttcgtcagtg
     1021 ttacttggtt tgcaatttct tttacttgtc gctgtgcatt ccccatcgca atactcaacc
     1081 cgctgtaatt caacatagca atgtcgtttt cttgatcgcc aaaagccatg atgtcactcg
     1141 attcgattcc aaggtaatcc gccagaaaaa caagtgaatg agctttagtg atacctgtag
     1201 gcgtgatttc taagaaatgc ggatcagaga atactgattg gataccatct gcttgcagat
     1261 ctctttgtag cttctgtagt ttttcttcac tcttatctgt taatgctaat ttaagatagc
     1321 taagagaagg atcttccaac atatttaaaa tttgatcaaa agaatggttc tgtaaattga
     1381 aatgttcata ataagggtca tctttgacta gatttgattc atcgaatgtc agctgatcat
     1441 cttgggtttc tcggctagca atgatggata ttttcgcttc ttgagcatag aagaaggctt
     1501 ttctcagtgt atcgctatct atttttgaac gtctgagaac tttcgccatt tttccatcct
     1561 tcatttcagc aatcagtgaa ccattggaag aaatcaaata gccaccgatt cctaattcgg
     1621 aaaaaatatc tttagcagaa atgctgttcc ttccggtagc gacggttacg attccgccat
     1681 tttcatcaaa tttccgaagt gcttggatat tttcttctgg tatctttcca tttcgatcaa
     1741 gcaaggtacc gtctaaatca atcgctgcta gtttcatttt atcttcctac tttcttttta
     1801 catatctatt ttcctgttac cttaagatta aatgagaatt taaaaaaatg aaactaactt
     1861 gctttgtcat tatgaatttt ttcaaaaaac attcttaaga aaaaggtggc tatatatagt
     1921 agtttttggt caataccttt gaataaaaag ccatgaaaaa cgaatagtta gcgcttaccg
     1981 atgcgttttg tgataaaaaa attttaaaat attcaatgaa aacaaagcat atattttgct
     2041 ttaaaaccaa atgaggaata ttctagatgt agaacaggtt agaaaaagat tagaaaaagg
     2101 agtgattttg atggagaaga gatacggcgt agttcctgtg gtaactgctt cagacgaaaa
     2161 ttatgctcct tacttgagcg tgatgatcgc aactgcatta gaaaattgca ataaaacaag
     2221 acgcataaaa ttttatgtga ttgacgatgg tctatcagaa tatagtaaag aaggattgga
     2281 agaaacggta aataaatatt caagtaatgc aagtatccaa ttcctgacag tggaaaaaga
     2341 tatctacgaa gacttcctag tcagtgacca tatcacaact accgcttact taagaatttc
     2401 tttaccaaac ttattagcta aagaggatta taagaaagtc ctttacttag attcagatgt
     2461 gttagtacta gacgatatcg taaaactata tgatgagccg ttaaatggaa aaacaatcgg
     2521 cgctattatc gatccaggcc aagtgaaagc tttggaaaga ttaggaatcg attccgatga
     2581 cttgtacttc aattcaggag tgatggtgat tgacattgat caatggaata aaaaagaaat
     2641 tacagaaaaa actatccatt acctcagtga aaatggcgat cgaatcatct atcacgacca
     2701 agatgctttg aatgctgtac tttatgaaga ttgggaacaa cttcatccaa aatggaacat
     2761 gcagacttcg ctgatttttg aacgtcatcc agcaccaaat gaaaaatatg aacgtcagta
     2821 taaagaagga aatgaaaaac cttcgatcgt tcactttaca ggacatgata aaccttggaa
     2881 tacgttgaaa gatcatccgt ataccaattt atacttaaaa aaattagcac acagtactct
     2941 aacgaaagta ggcgagatca atgaataaaa aagaaatagc agtagtcgca agttgtaaca
     3001 caaaattcgt accacattta gctgcattat ttgtctcagt attagataat tgcaacccgt
     3061 ctaaatttgt tcggttctat gtgattgacg atgatatcga ttttgaaagt aaacagcttt
     3121 tacgcttctc agtgaaaaac gcacgaatga actcagatgt ggaattcttg aaaatcaata
     3181 aagaattctt tacaaatgtg gtaatcagcg atcgtattcc agaaacagct tattatcgta
     3241 ttgcgattcc ggaattgttc cgcggcacag aagttgaacg tatcttatat atggattgcg
     3301 acatgatcgc tttacaagat atctctaaat tatggcgtct tgacttcggt gattcaatcg
     3361 tagcagctgt tgaagacgct gggttccatc aacgactgga aaaaatgaaa atttcagcta
     3421 aatcaatgcg ttatttcaac tcaggtttga tgctgatcaa tgtgaaaaaa tggttagatg
     3481 aaaatattac gcaaaaagta ttagatttca tcgaacataa tccagaaaaa ttacgattcc
     3541 atgaccaaga tgcattaaat gctatcttac atgaccgttg gttaccactt catccgcgtt
     3601 ggaatgcaca aggctatatc atggcaaaag caaaaaaaca tccaacagca gcaggtgaac
     3661 gtgaatacga agaaactcgc aacaatcctt acattatcca tttttcagga catgtgaaac
     3721 cgtggagcaa ggattttgaa gggccaacga agaaatatta cgaaaaatat gcagggatga
     3781 cggctttccg ttgtgtagct aaattcccta aatatccaaa atatgcaaaa gttcaaccaa
     3841 aaacagatgt agttgttaaa taatagaaga caacaactga agagggggag taggaatgga
     3901 aattacaatg tctaaaaatg cagtagagac gttaattgaa aaggttgggg aaaatacaaa
     3961 aatcgcactc gcgcttatca atgattccga tccatttcta agggacaaag gtgcttttgc
     4021 aaaaggcagc ttttttcaaa tcattccttt tgtttcggaa tttggagaat atgcgactaa
     4081 aatcgagcat ccattattgg acatctatac atctaaatta gagcaaaatt atttcggtaa
     4141 acgattgaac atggacttca acaaacagct tgacagcttt tcattagaaa atgaaatcgc
     4201 agtactcgat tataatatca aattaaagaa ctgcttcttc agctaatagt ttcgagaaag
     4261 tccaaaaagg aggtatacat tgagatacta ctttgtggat gaagaaaaga atgtaataga
     4321 aacagatgaa aaaaaatata attggctcgt acttgatagt gcaaagcccg aagagattga
     4381 gcaagcaatc gaagaattcg agcttcctga tgatattttc gtaggaaccg aatatccgga
     4441 agaagtttct cggatggagc gcctttatga gacgaaacta gagcatccat tttctttggt
     4501 agtgattaat ctagatcagt cagataatcg tatcgaaaaa aattaacgcc aatatctttt
     4561 gtactttccg ataatctctt gattacttgt atcgatagaa aaaccgaatt tgtggatcgg
     4621 ctgctgacaa agcatggaaa tcatttaaac tcgtttgaaa agatcatcac gtatacatta
     4681 ttagatattt acacccatta cgtgaaagaa ctaagagaga tgaaaaagcg aattgacgct
     4741 ttggataaag cagctcgtaa aacaacggaa aatgaagaac tgtataaaca ggcagatctt
     4801 gaaagagaca tcgtatatat cgatcatacc ttaagagatc aacgggaaac aatggatcaa
     4861 ttatggaatt ctgaaacttt catcaaacgt ttagacgatg aacagctact ctatgatgtc
     4921 catttgagac agcgacaaac agaaaaaatg atcgagatct atcgagattt attagagagt
     4981 attggtgatc tattcaacgg gatgatggac aataatctaa atcatatcat gaaatatcta
     5041 gattcagctg cattaatcat ttccgttccg gcgttgttcg cagggatttg gggaatgaat
     5101 acaggaggat taccgggtaa aagttctgct ctaggcttta tactcgtagt ctttggctct
     5161 ttgatagcag cagtagtttt aggttaccat ttataccgga aagattatac aaattaaaga
     5221 atctatttaa aacaggtatc aaacaaagaa atttgttttg gcaatacaat ttaaaaacta
     5281 ggaggaatac agcaatgaca gaaccaaaat taatcgaccc gcgaaacttg taccatacgg
     5341 agaaatttcc taaacaagat caggatacac cagctttaca gcagaatatg attcctgttc
     5401 ctgattgtgg agaagaatcc tatgaaggca ataatcaact agaaaaccgc cgtgtactaa
     5461 tcactggtgg agattcaggg atcggtcgtg cagcagcgat tgcatttgct agagaagggg
     5521 cagatatcgc tcttcaattc ttcccaggag aagaaaaaga tgcagaggaa gtagcaaaat
     5581 acgtgaaagt tgcaggacgt aagattgtct tactaccttt tgatcttcgt gacgaacaag
     5641 cacctaaaga aatcatagat aaagccgtga gtgaacttgg cgggctagat acgatggtac
     5701 taaacgcagg acagcaaatt tcttgtcagt ctattgctga gttaccactt gagcaagtca
     5761 aagacacatt tatgataaac atcatcgcta tgtttgcttt agtgaaagaa gctgttccgc
     5821 atatcccagc aggaggagca atcgtaacaa caacttctgt tcaagcattc aatccaagcg
     5881 aacatttatt agattacgca gcaacaaaag cttcaatcgc taactttacg atcggtttag
     5941 caaaacagct tgcacctaaa ggaatccgtg taaatggtgt agcacctggt ccaatctgga
     6001 caccattaca actagacgaa ggacaacctt ctgattcgat ccctgaattt ggtcagcaaa
     6061 gtttactaga acgtgcaggt cagccaggag aattagcacc agtttatgtt ttcttagcat
     6121 cgaataaagc aagttatgtt acagcccaaa tttacggagt aactggtgga gaagcgatca
     6181 acttataaga agttgatcgt ttcaccccta tgaggaggtg cgaaaatgaa taaaggtgta
     6241 aaaacgatcg gagtgatcgg aacattactt ttgctatctg tgcttttgtt tgcgatacta
     6301 ttaagtgcaa cctatccatt gccttttcag ctagagaagt ttcgattctt ttccatcact
     6361 aattcatacg tgcaacaata tgtattttgg cttgccgttg catttgctat tttgacaatt
     6421 atcacgttac ttgttttcct gttttatcca aaaacaatcg gaaactttct actgaaacat
     6481 ggtgatgggg agttgacgtt ggataaaaaa gcaattgaag gaatggttcg ttctcacttg
     6541 catgaagatg aattcatcca ttcaccaaaa gtaaatgtca aagcaacgaa aaacaagatc
     6601 gccgtcaatg taaaagggga gttgaaacga acttcagcac tcattggtaa aacaggaaca
     6661 ttgatgaaag aaatcgaaaa tgaagtacaa cacatattgg gaacaaaaga gccagtgaaa
     6721 gtatcggtga aatacacagg ctttgaagaa ccagctaaac gaagcaatga ccgcaaacga
     6781 gtagaatagg gggggaccaa aaatgaaaga actattttcg acatacaagc tccctatcat
     6841 ctttggggta cttggattga tattagccgt tttatggatc accgtgggct ttttcaagac
     6901 cttattgatc ttgatcatgg cagcgatcgg cgtcgctatc ggtttttatc tgaaacaaac
     6961 gaaaatctta gatcactatt ttaaatctta ggaggaaaca tccatgaata acaataacaa
     7021 aaataataac aataaaatga acaaccaaaa accagtgtct gcacatccag acccaacgac
     7081 accaaaccaa tcaaatggtg tgaacgatga aaagaacaaa acagcaccag tatctgcaca
     7141 tccagatcca gtagtcccta acgttcaaca aggagtagaa gagaagaaac atgatgcaga
     7201 aaagcatgca cctcatcatc caggaactcc agaatctaaa gttccagaac aacatgatgc
     7261 aatcgatcct tctaaacctg tggaagagca aaaacatcct tctgaccatg cgaaagcaca
     7321 agaaaaactt agttctgacc acacaaacgg acaaggaaaa cttggttctg atcatacaaa
     7381 taaccaagga aagcatgatt ctgaacagga agattcaatg cgcggtgagc tgaattatga
     7441 agataaagtt gtgcaaaaaa tcatcggaat cgcaattgaa caagtagacg gtttattatc
     7501 tgcaaacggt ggtttcttct ctaatgtggc aggaaaactt gtgaatacag ataatgtaac
     7561 ggctgggatc gaaacagaag tcggtaaaaa acaagtagca gttgatatgg atgtcattgt
     7621 ggaatatggc aaagatatcg aaaaaatctt tgaagaaatg caagaagtaa tcggcaaaga
     7681 agtaaaaaat atgacacatt tagaagtgat cgaagtcaac gctaacgtag tggacatcaa
     7741 aacaaaagaa gaatttgaaa aagatcaaga aacggtgcaa gacaaagtaa ctgacgcagc
     7801 gaaaaaaacc ggtgaatttg cttcgaatca aacagataaa gtaaaatcag cagctggaag
     7861 cggcgcacaa aaagtaaaag aaaatacaga accacgggtt cagtaataag gaagtaaaac
     7921 attaggagga acgaaacatg ggatttattt ggtcacttat cgtcggagga attatcggag
     7981 caattgcagg agcaatcacg aataaaggtt cttcgatggg gattattgca aatgtcgtag
     8041 caggtttagt tggatcagca cttggtcaag cattattagg ttcttgggga ccaagtattg
     8101 caggaatggc aatcgtgcca tcattgattg gtgccatcat tttagtacta atcgtatcat
     8161 tctttgctcg aaaactgtaa aaagactttt aaaaagaggt cgtgaaaaag ctgttcttca
     8221 tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt ggttgggcat
     8281 attatcgaag atgcaagctt ttgaacactg tttatacgga ataagaggct gtgacaagac
     8341 ttttgtcaca gcctcttatt tatgcgggca aattcccaat tagattttta aaagtttttc
     8401 cttaaatgtg tctttattga tacagagaag cttctttaat aaaacaatgc ctccctaaat
     8461 tttcttgaga taggaaaggt gaacatacaa aataatacga ccactttgaa aacccagatg
     8521 atccacaaat ggatcgtatg atactgatga agtaaaaagc aatggatcag aaactcaaag
     8581 agattgaaaa agacaaggaa gaaataatat ctctttttta ctcttgtctg ttttagccaa
     8641 taatagctcg taaagtaatc tagacaaaca aatagaagta aacaaagttt cgtaagagca
     8701 gcaatcgtat catgttgctc tgctagacga ttgacgagca ggaaaaatgt tggtaatgga
     8761 atatagatca cgagtaatga aagaaaaaag taaacaataa atggcatact attcctccta
     8821 attgtgtgag ttcgccctca ttttaaaata acgatatttg tttgtgaagc tttttcgtgt
     8881 cgtaacaaat gttatctaat gtatttttaa ataaataatc attattatca aaataat
//
LOCUS       DACGDM010000101         8818 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.107, whole genome shotgun sequence.
ACCESSION   DACGDM010000101 DACGDM010000000
VERSION     DACGDM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.107"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(138..428)
                     /locus_tag="IXR05_002419"
     CDS             complement(138..428)
                     /locus_tag="IXR05_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260890.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="IXR05_002420"
     CDS             complement(546..806)
                     /locus_tag="IXR05_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260891.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="IXR05_002421"
     CDS             complement(943..1356)
                     /locus_tag="IXR05_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAQ4260892.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="IXR05_002422"
     CDS             complement(1812..2297)
                     /locus_tag="IXR05_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260893.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="IXR05_002423"
     CDS             complement(2436..2651)
                     /locus_tag="IXR05_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAQ4260894.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="IXR05_002424"
     CDS             2875..3675
                     /locus_tag="IXR05_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4260895.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIKEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="IXR05_002425"
     CDS             3694..5562
                     /locus_tag="IXR05_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4260896.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="IXR05_002426"
     CDS             5555..6046
                     /locus_tag="IXR05_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAQ4260897.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="IXR05_002427"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="IXR05_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAQ4260898.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..7601
                     /locus_tag="IXR05_002428"
     CDS             6606..7601
                     /locus_tag="IXR05_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAQ4260899.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
     gene            complement(7743..>8818)
                     /locus_tag="IXR05_002429"
     CDS             complement(7743..>8818)
                     /locus_tag="IXR05_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4260900.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         3047 a         1425 c         1682 g         2664 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacataaaag aagggatata taaagtaatg aaacatttta agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgttcccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg agtttagtct aatggtgata
     7621 agtcaagatg aaatttaaga ttttctttat tgagtaatat gttttgaagc gcacgaaact
     7681 agacccgatc aaaatcaaat ttttttcggg ttgattcaag gatttgcgtc aataacggat
     7741 tgttatttct ctatcacact ccttggtggc gtatagagtt ggtgtttacg tagtagcgta
     7801 tccaccagac gcgtaaattt tcttgcggtt aggacgagtg cacgtttgtg ttgatgcttt
     7861 ggaacctcct tatatttact ttgataaaaa gctttgtatt caggaagata attttttaca
     7921 gagttggcag cttcaactaa gtagtatcta aaatatcgat ttccttgttt tgtcagaggt
     7981 gtattttgcg actgatagtt tccagattgg ttcactttcc aacttaatcc agcgtatttt
     8041 gccaattttg tctgatcttc aaatctttcg atttgaccaa tttcagcgat taaaccggca
     8101 gcatagactt taccaacgcc tggaatactg gttaagcatt gatattctgg aatgacaaca
     8161 attacttgtt cgatggcttt atctaattct ttgatatttt tttcaagtgc tcgtatttct
     8221 cgtacgagaa cacttaaaac aacattaatt gattcttgtg caagagcacc taggcggtaa
     8281 ctcatggtaa ttgcacgttg aattgcttta gcgatttttt ctggttgctt gaaacggcct
     8341 tttccttttt cttgaagtaa atcacagaaa gcttctaaag gaagctcagc aagttcatcc
     8401 aatgtgaaat cttccgtcat gagtgaaatg agggttgcac taaaaagact cgtcgattcg
     8461 tctcgcattt ctcgagcaag cgtattacat ttgtacgtta gattttcaag aaaatgttgc
     8521 tttgtacgaa tcaattgctt aataagttga tagcgagtac gtgttaaacg ctgtaaggcc
     8581 atgtatttct cttctttgat aggggaagtt gtgaatcgtt gaatacgcaa gaaatcagcg
     8641 attcttaatg catcgtttcg atcagtttta ttctcatcaa acatgcgact aaattgtttc
     8701 acccgaaaag gattttcaat cgttacaagt gtgttgagct tctttagttt ctcatcttca
     8761 tgaaaaaaca tggaaggatg gaagctgtac atggacgttg actccatgcc aatcacaa
//
LOCUS       DACGDM010000102         8798 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.108, whole genome shotgun sequence.
ACCESSION   DACGDM010000102 DACGDM010000000
VERSION     DACGDM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.108"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..776
                     /gene="menA"
                     /locus_tag="IXR05_002430"
     CDS             <1..776
                     /gene="menA"
                     /locus_tag="IXR05_002430"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAQ4260901.1"
                     /translation="YMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFVIG
                     VILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVYVN
                     TFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRDIE
                     NHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKHLD
                     QFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1590..2936)
                     /gene="gor"
                     /locus_tag="IXR05_002431"
     CDS             complement(1590..2936)
                     /gene="gor"
                     /locus_tag="IXR05_002431"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAQ4260902.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(3070..4311)
                     /locus_tag="IXR05_002432"
     CDS             complement(3070..4311)
                     /locus_tag="IXR05_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4260903.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(4329..5252)
                     /locus_tag="IXR05_002433"
     CDS             complement(4329..5252)
                     /locus_tag="IXR05_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4260904.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(5473..7965)
                     /locus_tag="IXR05_002434"
     CDS             complement(5473..7965)
                     /locus_tag="IXR05_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAQ4260905.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(7972..8439)
                     /locus_tag="IXR05_002435"
     CDS             complement(7972..8439)
                     /locus_tag="IXR05_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAQ4260906.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(8575..8648)
                     /locus_tag="IXR05_002436"
     tRNA            complement(8575..8648)
                     /locus_tag="IXR05_002436"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8612..8614),aa:Arg,seq:acg)
     gene            complement(8706..8779)
                     /locus_tag="IXR05_002437"
     tRNA            complement(8706..8779)
                     /locus_tag="IXR05_002437"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8743..8745),aa:Pro,seq:tgg)
BASE COUNT         2440 a         1867 c         1461 g         3030 t
ORIGIN      
        1 attacatgga ttatgaaaag gctcattctg aagtatataa gtatgaagaa aatgtcattg
       61 gccgcagaaa tctatctcct gtattgattc gaaacatgat tttagctatg attgcatttg
      121 tttttgttat cggcgttatt ctaacgatca atacgggttg gcttttactt ttgatgggat
      181 ttatctgttg ttttattgga gtattctata cattcggacc gattccttta tctcgaatgc
      241 ctttagggga aattttcagt ggggtgacta tgggccttgg aatttttgcc atggtcgttt
      301 atgtcaatac attcggttca gatgtctatg atctgacagt caacttttca tctggacaat
      361 ttgatttggt aggaaatctt tgggctatag cagcaatcgt attagcttcc ttacccttgg
      421 tgtttacgat tgccaatatc atgttggcta ataatttgcg ggatcttgac cgtgatattg
      481 aaaatcatcg ctatacacta gttttttata tcggacgtcc tgcgggaaca gtcttattcc
      541 agctattgat gtatgcttgc tatttcgtga ttttaatggg gttgttgagc ggtatctatg
      601 aatggccgat cttggtcacc ttcttgacct tgccaattgt gaagaagcat ttggatcaat
      661 tcaagcaaac gttaccccag cctatcagtt tcagctattc catcaaaaat atggtcttat
      721 tcaatgccag ttatgtattg gggctattac taacaatcat tatgcaagcc atttaacagc
      781 atgaagaggt tgtgaaaaaa ctgccctgca tcaagtaata agaacagcca aataaaaata
      841 gctccttata tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg
      901 tttatcagga ggttgtgaaa aagtcgctta gtttcgagta ttaagaaaaa ttttgtgaaa
      961 atggctttcc acatttttgc ataaatttgg cttaataccg agaaactggc ttttgaacac
     1021 cgtttatcag aggttgtaaa atcagtgttt tgtcctgagt attagagaaa caaatggaaa
     1081 aatagttcct catattttgc cgttttttga gctaataccg aaggacagct gattgaacac
     1141 tatttgttcg gaaaaagtga ctaactatga cacaattttt ttcacagtcc cttttttcac
     1201 ttgatttgat tcgtaccagc gaacttgacg agaactttct tggtttggta actatatggt
     1261 attcttttaa catcctcgtt tgcttcttct aatttattta tacaaagtca cactttttta
     1321 aacatctgtt cttcgataca tttctatttc ttttaaacat cgataccaat attttgaact
     1381 taagagtgca taccaaatgg attcatttac tcttcgtcag ttacgaagat aatcaaaatc
     1441 tccaacttcc ctacttattt cgttttgaga attatcgaag caatcttaca taaataacta
     1501 aaaaacaaaa aaccagaaaa tcagtatact gattttctgg ttttacatgg tttgttcaat
     1561 aaaaagctgt tggaactgtt aatattaaat tatcgcatcg ttacgaattc ttccgctcct
     1621 gttggatgga tggctactgt attgtcaaag tcttctttag ttgcacccat cttgatagcc
     1681 acggcaaaac cttgcagcat ctcatcgaca ccaacaccaa tagcatgtaa gccgacgatt
     1741 ctttcttctt ttccgacaca gatcaatttc atttcgcatt tttggcgata atcatttaat
     1801 gcaaagtaca ttggggtaaa gcgtgaacga taaactttca attcattttc gccatatttt
     1861 tccaatgctt cttcttctgt caaaccaatt gttgcaattg gtggatgcgt aaagacgact
     1921 gtcggaacaa gtttatagtc aagataagaa tctttctttc cattaaataa acgttctgat
     1981 aaacgtctac cagctgcgat tgcaacagga gtcagatcta atttaccgat cacatcacca
     2041 acagcaaaaa tatgttcatc cgttgtattt tggtatttat ctactttgat aaaccctttt
     2101 ttgtccaatt ccacatttgt attttccaga cctaattttt cggtattcgg tacacgtcca
     2161 ccggcaaaaa gtacacaatc accagttaag gtttcaccat tttcaaatag caccgtatat
     2221 tcgtcattgt ttttagtaat ttctttagca atatgatgtg cgtaagtttt tattccagct
     2281 tcttggtaca tttggatcaa attgtccgaa agcattttat caaacgttct aagtggtcgt
     2341 tcttttcgat atgcccacat gacttcacta cctaaaccac gaaatacacc tgaaagttca
     2401 gccgcaatgt atccagcacc taaaacgatt gctctcttag gtaactctgt taattcaaaa
     2461 aatccatttg aatcaattgc gtattctcca ccaggaatgg tcattttact tgcacggcct
     2521 ccagtagcga tcaagatttt aggagcacga taggtttcac cgtttacttc gatcgtttga
     2581 ctatcgataa aagtagcgta accttttata gcctcgacat gattgctatc taatcctctt
     2641 tgataagcac cgtgtagaaa atcaatatat ttttctcgtc tttctactag accggcgaaa
     2701 tcaacatttt ttaaatctgc ttggataccg taacttgagg catctcgttc aattgtttcc
     2761 aaaatcgtac ttgcttgcca cataactttt ttaggtacac aaccgacgtt gacacatgtt
     2821 ccgcccaatt cattcgcttc aatcagcaaa acttttgcgc catgcatccc tgctctgttt
     2881 gctgaagcaa taccgccaga gccgccacca attacgatgt aatcatatat ttgcattttg
     2941 ttcctcctta ttgaagagat caatcaaaac ctttatttaa cgatcctttt tctacagaaa
     3001 acaagtgtaa cacttttctt gaattttgta tgcgaagatg cttaaaacag ggatatatca
     3061 gctttttcct tatttacgtt ttcggatcat atctccaggt ttcaccggct gtgcgactgg
     3121 catagttaaa atcatcattg gatttggtgc tcggtcaatg gattcgcctt cttcattatg
     3181 cataacttca acggtttgac tgaaatgact gaatcctgga ccataaaatt cgatttcatc
     3241 tcctacagaa aacaagtttc tctgacgtat cgtagcaatc tgtgttgcct catcataaga
     3301 taatacttca ccgacaaatt tatatactgg gattttacga cgttcaccga ataattgttc
     3361 gttttcagtt ggtgtattgt agtaaaaacc tgtagctaat tctcgttgtg ctactttcca
     3421 taactcgtcg atccattctt gcttgcagac atagttttca ggatcttcca tataactgtc
     3481 tacagccgct ttatagacat ttgacaccgt agatacataa tggatcgatt tcattcttcc
     3541 ttcgatcttg aagctgtcta cgccgttttc aatcaattct ggaatatgtt cgatcattga
     3601 catatccact gcactcatcg agaattcttc ttccacttcg cctgtatcag ttaaactgtt
     3661 tcgttcttga ccaaaaggca tatcgaacaa tccatacttc cagcgacaag attgagaaca
     3721 tccgccacgg tttgcatccc gcatcgacat atggttggac aatgtgcatc gaccagaata
     3781 agagatacac atggcaccat ggataaatgc ttcgatttcg gtatccgtat ttttacgaat
     3841 ctctgccact tcctccattg aaacttcacg agctaaaacg acacgttcca acccttcttc
     3901 tttccagaat tccaatgtct caaaattagt tgctgaagct tgagtggata aatggatcgg
     3961 cagacctggg gcttctgtcg cacaaatttc gatcaaagct ggatcagaaa caatcactgc
     4021 agaaataccg acatcacgca aactgcggaa aaattcccct gctccatctt catttccttc
     4081 atgggtgacc atattagcag caacgtatac cttcgcatca tgttcttttg caaaagcaac
     4141 tccttcagcc atttcttcat aagtaaaatt acctgcacgg cttcttaaac catatgcatt
     4201 cccgccaata tatactgcat ctgctccata atggatcgcg gtttttaact tttccagtgt
     4261 tcctgctggc gctaggattt ctggtcgttt caattttctt tttactgtca tttctttcat
     4321 catactcctt atttgatagc agaaggatca atataaaaga atcctgtatc taattcacgg
     4381 ttttcaggat gcaatttact gatttcgcta gtcatttttt ccgctttttc ttgatcccag
     4441 ctaccttcta aaatttgttt ttttgcttcg gcgaatagtc gagtgatgtt tacgaatttt
     4501 tcgcctggag taaataatcc gtccaatttc catgtacagt aatgatgctg ataaagttca
     4561 ttcaattcat tcgagagatt cagatcattg ctggcaaaaa tatgtgtgcc atgactatct
     4621 tcataaatag aataatgtgt ctcttctttt ttaggttccg agataaaaag acctctttca
     4681 cgatcttttt gttcgtcttg tttcgtatag ttatagtaat tctgtagcag tggacgtttg
     4741 gattgatgga tgcatgtagc accatacaca agggtttcta caggaatatc gagtttttct
     4801 tccatcgcct tcatctcttc aaaaggaact tcacgagcaa gtactgctcc aactgcgcct
     4861 tttttcgccc agaaattgat ttgacgtgcg ctcgttacta atgtttcagc atcataaata
     4921 tacggtatac gcaattcagg attttttttc atcgtataaa taatacctgt atcaccaact
     4981 gtgatcacat ctacgtttat ttcttttaaa aaagccaaat attcaggtac atttttcatt
     5041 ttttcaggat gaatgatccc atttacagca atattcgctt ttttaccata cttgtgtgct
     5101 aattctacca attgtcgctg ttcttctcgt gtaaatgaag caggcagacg caatccaaat
     5161 tgctcttcac cgaaatatag tgtatctgca cctgcagcaa gcaactgttc tgcttgttca
     5221 atagtttcta ctgtggttat gagttcgatc ataattttct cctcctacaa cttcataata
     5281 gtagcatagc tctaaaaact ttccaatact tcttctattt aaagtcggat ttttgaaaat
     5341 tatttcacaa aaaatcaaaa taaagttcga tatattctgt ccaaatataa aaagagattg
     5401 tgacaaaaat cttgtcacaa cctcttaatc aagtcttact attataaaaa ttcagctaca
     5461 caggccaagt aactataggg aacctactgt ttccttttta ggtccgcgaa cattcaatgt
     5521 gatcttacct tttgaagcac ctactgttac gtggtcacct aaacgaattt ctccgccaag
     5581 caaagcctcg ctcaatcgat cttcaatttc tttttgaagt gcgcgacgga ttggacgtgc
     5641 accatattca ggatcaaatc cagctttccc gatcacatcg attgcagatg gtgtgatttt
     5701 cacttgaata tcttgttctt tcaatcgttt gataatcgct ttgctcatga tttggacgat
     5761 tgtatggatt tcatctttac tcaatgaatg gaagacgaca gtctcatcga ttcgattcaa
     5821 gaattcaggt cggaaagctt tctttaactc ttctaagata cgtttttgca tggctttgtg
     5881 atctttagta acatcttgga cattgaatcc gacatttttt tcttctcgaa tttgtgtcgc
     5941 tccgatattt gaagtcataa tcatgattgt atttctaaag tccacttttc tacctttaga
     6001 atctgttaaa tgaccatcat ccaatacttg cagaagtaaa ttgaaaacgt ctggatgtgc
     6061 tttctccact tcatctaaga gaatcactga atatggtttt tgacgaattt tttctgtcaa
     6121 ctgtccacct tcatcatacc ctacgtatcc tggaggagac ccgattaatc ggcttgtact
     6181 gtatttttcc ataaattctg acatatcaac acggatcagg gcatcttcac ttccaaacat
     6241 gacttctgaa agtgctttgg ccaattctgt ttttccgaca ccagttggtc caaggaacat
     6301 gaatgaacca attggacgat caggatcttt caatccgctt cgtgcacggc ggatcgcacg
     6361 tgaaactgct ttgacagcct catcttgacc aacgacacgt tcatgcagaa gtccttccag
     6421 ttctaacaag cgttcgcttt cttttttctc caactgctgt agagggacac cagtccactc
     6481 cgatacaact gtagcaacat cttcttctgt tacacgatca gaataacctt gctcctgttt
     6541 tgcttcaatt gcagaaactt tttgcagctt tttacgtagt gctttttctt gtctgcgtaa
     6601 ttgagcagca ttttcaaagt cttgtttttg gatcgctgct tccttttctt gtactagttc
     6661 atcgatttct agtttgatca cagttgattt tgttaagtga tcggtttgat ccaaacggac
     6721 tttcgctgct gattcatcga tcaaatcaat tgctttatcg ggtagttgac gagaagtgat
     6781 ataacgaaca gaaagattga ctgctgctcg tacagcttca tctgtgatct ccactccatg
     6841 gtgctcttca tatcttgtac gtaatccttg aagaatcact tctgcttctt caggagttgg
     6901 ctcatctact tgaatgcgag caaaacgtcg ctctaatgca gaatcttttt cgatatattt
     6961 ttgatattca tctagggtcg ttgctccgat cgtttgtaat tctcctcgag ctaacgccgg
     7021 tttcaagata ttcgaagcat caattgctcc ttctgctcca cctgcaccaa ttaaggtatg
     7081 caattcatca atgaataaga ttacttgacc atcattatag atttcgtcga tgaccttttt
     7141 cattcgatct tcaaattcac cgcgatattt cgtaccagca accaaagatc ccatatcaag
     7201 catcatcagg cgcttttctt gcatgtcttc tggcacttca cctaaaatga ttttttgagc
     7261 taacccttca gcaatggctg ttttgcctac accaggttca cccaccagta cagggttatt
     7321 ctttgtccgt cggctaagaa tctggataag ccgtttcact tctctcgaac gaccaacaac
     7381 tgggtccagc ttgttttctt ttgctaattt cgtcaaatca cgtgctaatg aatctagcgt
     7441 aggtgttcct tgcggtgttt gccgtttatc ttgtacattt acatttctac gacgattcat
     7501 tccttttcca gcagaatcac cagctagccc cattttttgt ttcagaactt gacgggcttt
     7561 tgaaaggctg atacctaagt tgatcatgat tcgagtagcc atgatacttt catcttttaa
     7621 taagctcatc aaaatatgtt ctgttccaac tttttgagaa ccagttttct tcacttcgct
     7681 gctagctaaa gcaaaaactt gtttcattct tggtgaatat ggaagaaaga ctcctttagg
     7741 gtaagaacgg ataccaccat aaccaatcag atgttcaatt tcttcataaa tttccgtttc
     7801 attcaaatcc atttcacgta atacttttcc agcaattcca ttttgctcga ccactaaggc
     7861 tagtaaaaca tgttctgaac taactgattg atgtttcaac cgttttgctt cttcttgtgc
     7921 aatttctaat actgcttggg ctctttcagt aaaaagttct tccatctaat ctcacttccc
     7981 atcttcataa cttaaacgtt ccagaaatgc tcggagaatc cgagcacgtg tatgatcttc
     8041 atattcattg aaattcaatg tgttttttgc aattgcactc aacatcaagt ttccttcttt
     8101 ttttgtaatt atttggtctt cataaagttt ttgaataata gcaaaagcat ttttctcact
     8161 gattgtatca tcaaataact gatttatctg ctcaagtaat tgttttttat ctgaaatcct
     8221 tacttttgca attcgtatat aaccaccacc accacgtttg ctttctacta gataaccacg
     8281 ttggatggta aaacgggtat taatcacata gttgatttgt gaaggaacac agttaaagag
     8341 gtctgccatt tcaatccttc gaatctcgat catttcacta ttttccagaa ttttctttat
     8401 atatgattca attaaatccg aggtattctg atgtgccatc ttattcattc cctttgacta
     8461 atattgacct taattataac gaatttgata atagaaagaa agaagaacgc tttttgttaa
     8521 ataaatcctt tagaatcaac aaaaaaaaat acggaatata ctattccgta tcgacgcgcc
     8581 caagaggagt cgaaccccta accttttgat ccgtagtcaa acactctatc cagttgagct
     8641 atgggcgcat attcaattta aaaaaattat aaatcatttg aaaacaaaaa gcaagataaa
     8701 aaaaatcggg aagacaggat tcgaacctgc gaccccttgg tcccaaacca agtgctctac
     8761 caagctgagc tacttcccgt ttaaaaaata aaaaagac
//
LOCUS       DACGDM010000103         8494 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.109, whole genome shotgun sequence.
ACCESSION   DACGDM010000103 DACGDM010000000
VERSION     DACGDM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.109"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..173)
                     /locus_tag="IXR05_002438"
     CDS             complement(<1..173)
                     /locus_tag="IXR05_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4260907.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="IXR05_002439"
     CDS             complement(593..1714)
                     /locus_tag="IXR05_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAQ4260908.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /locus_tag="IXR05_002440"
     CDS             2042..3451
                     /locus_tag="IXR05_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAQ4260909.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="IXR05_002441"
     CDS             3448..4176
                     /locus_tag="IXR05_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4260910.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="IXR05_002442"
     CDS             complement(4304..5215)
                     /locus_tag="IXR05_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4260911.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="IXR05_002443"
     CDS             complement(5232..6239)
                     /locus_tag="IXR05_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAQ4260912.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="IXR05_002444"
     CDS             complement(6236..8365)
                     /locus_tag="IXR05_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4260913.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="IXR05_002445"
     CDS             complement(8370..8477)
                     /locus_tag="IXR05_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260914.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2681 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DACGDM010000104         8381 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.110, whole genome shotgun sequence.
ACCESSION   DACGDM010000104 DACGDM010000000
VERSION     DACGDM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.110"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..493)
                     /locus_tag="IXR05_002446"
     CDS             complement(<1..493)
                     /locus_tag="IXR05_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAQ4260915.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFIN"
     gene            complement(623..1333)
                     /gene="budA"
                     /locus_tag="IXR05_002447"
     CDS             complement(623..1333)
                     /gene="budA"
                     /locus_tag="IXR05_002447"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAQ4260916.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNIQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(1346..3010)
                     /gene="alsS"
                     /locus_tag="IXR05_002448"
     CDS             complement(1346..3010)
                     /gene="alsS"
                     /locus_tag="IXR05_002448"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAQ4260917.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(3218..3880)
                     /locus_tag="IXR05_002449"
     CDS             complement(3218..3880)
                     /locus_tag="IXR05_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4260918.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKENSFSPVRLFIKMFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSTNCWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(3890..4705)
                     /locus_tag="IXR05_002450"
     CDS             complement(3890..4705)
                     /locus_tag="IXR05_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4260919.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(4966..5409)
                     /locus_tag="IXR05_002451"
     CDS             complement(4966..5409)
                     /locus_tag="IXR05_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAQ4260920.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     HSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(5543..5881)
                     /locus_tag="IXR05_002452"
                     /pseudo
     CDS             complement(5543..5881)
                     /locus_tag="IXR05_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(5869..6246)
                     /locus_tag="IXR05_002453"
     CDS             complement(5869..6246)
                     /locus_tag="IXR05_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4260921.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            6470..7663
                     /locus_tag="IXR05_002454"
     CDS             6470..7663
                     /locus_tag="IXR05_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4260922.1"
                     /translation="MTTYQRKVLVSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFVMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(7829..8251)
                     /locus_tag="IXR05_002455"
     CDS             complement(7829..8251)
                     /locus_tag="IXR05_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4260923.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQQYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
BASE COUNT         2466 a         1689 c         1415 g         2811 t
ORIGIN      
        1 tattaataaa tgaaaaagca tttatattaa aatttgctaa taaaagatct acatattttt
       61 ctagaaatgc ttgatcgatt tcatcatacc ctttcgttac tccgcaatcg atatctaaaa
      121 caccgattaa attaccttct tttaccattg gcactacgat ttctgattgt gcggctgaat
      181 cgcaggaaat gtaatttgca tgggttttga catcatcaac gatcaatgtt tcttgttttt
      241 cagctgattc tccacaaact ccttttccca tcttgatacg tgtgcaagaa actcgccctt
      301 ggaacggtcc taaaatcaat tcattaccat cgaataaata atatcctgca aagacagtct
      361 caggcaaagt ctcattcaac aatgcagatg aatttgctaa atttgctaac cagttatctt
      421 ctgcttctaa taatccttgt tgctgtaata ataaaatttc gtatgcatct tttttctgtt
      481 tttctgtcca catgataaaa accgctcctt tttgatctat ggagaagatt atagctcagt
      541 ttttttgtaa acgctaggtt tcctcctcaa aaaaacgaga tacgtcaggt taatcacctt
      601 gaacgcatct cgctgtcttt ttctattctg cttgttggat ttctgctgct aaatcagcat
      661 aatcaatcgt ttcgtgaaca aaagtcggat catcaactgg aaaatgctgt acaagggacg
      721 agatgcggct aatctcaact tttccttcag ccacttcaaa atccattaca tgtccgccaa
      781 atgtatgtgt atcatcgata aaatgcaggt gaaatcccgc tgcagcaact ccttggaata
      841 attcaggcgt aaagaacccg actaatgttc cttggatatt gctttgttgg aattctggtt
      901 gagactctga aatttttgct agtcttctgt aaggtttttc ttgcttcggc atgatacgga
      961 tgtgcatatt tttgaataat ccagttatct tcactgccaa aaataggttt tccccggctt
     1021 ctcttactaa tatgtctttt ttcaattgtt ctccatctgc agtttttgag acagaaaaac
     1081 tagtatctgg cgtaaaatct gtaattgctg catagggggt aagttcactt ccatctaatt
     1141 gggcaactga gccatctgat cttccttgat aagctacgcc atctaaaaag atgacttcac
     1201 catcaagacc atgcaatgtt cccaatccca gagttccttt ttctaatata tgagcaatcg
     1261 tttctgttcc atccatcaag ccggccatca aagctcctaa tgtcccgtgc tggtataaga
     1321 ttttttcagt catgtcgaca cttccttaat agaattgatc tggtaagatt gtttctccca
     1381 atttctcatt atcacggtaa tcaatcggaa tatcaataat tacgggtcct tctgtcgcaa
     1441 atccttcttc taaagctttt tctaattcct ctacacttgt agctcggatt cctttagcgc
     1501 caaaagcttc tgcatatttc acaaaatcaa ctggaccaaa gtctacacct gacgcccgct
     1561 gatatttcat tttttcttgg aactctacca tattgtagtg tccatcattc caaatcaaat
     1621 gaacgatatt caatttttta cgtaccgccg tttctaaatc ctgggcagag aataaaaatc
     1681 ccccatcgcc ggaaactgat acgatttgtg tatttggacg caccaatgca gcagaaatcg
     1741 cccatggcaa tgcaacacca agcgtttgca taccattact gaataacaaa tgacgaggtt
     1801 cataacttct aaagtggcgt gccatccaaa tataatgact acctacatct acggtaacag
     1861 tcatatcatc tgttactttt gactgaagcg tgttaataac ttctaaagga tgcaagatac
     1921 ctgcttctcc ttttgattga acaatgtccc gctccgttaa ttttgcttga agagatgcta
     1981 aatattcttt tgcatcttct gacacttgtt gaggctctaa tgaacctgtc aataaatcaa
     2041 gagtggctga gatatcaccg atcaattctc tttcaggctg cataaaagga tcgatttcag
     2101 ctggcgcttc atcgatcaca atgatccgcg catctttttc cgcattccag tttcttgctt
     2161 catattcgat tggatcatag ccaattgcaa taactagatc acttcgtttc aaaagcatat
     2221 ctcctggttg gtttctaaat aaacccacac gaccaaagaa atgcgcttct aattcacgtg
     2281 agatcactcc agctgcttgg aatgtctcta caacaggcaa tgctgtcttt tcaactaatt
     2341 gcctgatggc taacgtttct ttttcacttg atcctcgcat acctactaat agtaccggta
     2401 gttttgcttc tctaatgcgt tcagctaggt aacggatatc atctgcagaa gcagaaccta
     2461 atttaggatc gctcaatggc ttgatgacat taccttggac aggtgcatcc actacatctt
     2521 gcgggatact gataaagctc gcgccttttt ttgaactctt agccatacga taagcattgg
     2581 caatcacttc tgaaattgtt tctggatctt ggatttctgc actgtatttt gtgattggct
     2641 ggaacagtgc tgcattatcc atgctttgat gggtcaactt caatagatcg cttcgtttta
     2701 cttgtccggc aattgctaaa actgggtcac cttctgctgt cgctgttacc aaacctgtag
     2761 ctaagttact agcaccagga ccacttgttg cgataactac tcctggctct cctgtaatac
     2821 gtccgattgc ttgtgccata aatgcagcat tttgttcgtg acgagtcacg attaattcag
     2881 gaccttgatc ctctaattca ttaaatacac catcgatttt tgcacctggt ataccgaata
     2941 cataatcaac atgatgatta atcaaacttt ctactacaga tttcgaacct tgtttcattt
     3001 tttcagccat tgaacatcgt cctttttatg ctttattttt aattattagt tagaaataat
     3061 cacaaataag tgatacagtt tctaaacctg tttcatacaa aagtatagca cgttttattt
     3121 catttgttta gccatatgtt tcaaaaaatg aaaaagaatg acagttttta cataaaaaaa
     3181 actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata gttctcatca
     3241 atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt agaatacacc
     3301 attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa tctagtaaac
     3361 tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga tttggtttcg
     3421 acgctggatt tctcacctga aaataccagc agttggtgct aaaggaaact gataaacaag
     3481 caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata aaaaagaaac
     3541 aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa aatcccttta
     3601 gccaaaattg gcgaaacatc tttatgaaca aacgtactgg tgaaaaacta ttttcttttg
     3661 ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa agtaaagaaa
     3721 aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct gctatataca
     3781 agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac caataaaaga
     3841 attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc tattccttca
     3901 ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat ataaaagcaa
     3961 caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca tcaaatagcc
     4021 caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac aaataaatga
     4081 atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa ctggcaatcg
     4141 ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat aagccatcga
     4201 tccgcgcact ctcacataaa gaatctggga tactactgta atattgcttc aacaagaaca
     4261 caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatct gttaaaccca
     4321 cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca gcaatcgtgc
     4381 cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa aacccgtaag
     4441 cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa aaagctgtat
     4501 tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc tctaaatgcc
     4561 aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct ttgaatgaag
     4621 cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc agcagaatca
     4681 tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt tttctttcat
     4741 ttcgaacacc tccaaagtta taatcttcat ttctttgtaa tgattacaat ccagaacaac
     4801 ggttattata gctgattcat ttccgttctt cttatttttg taagcgctta tttaacaagt
     4861 tatgtaaatc tctttatttt tttgatttaa aaatgaaaaa atacaaaagc aagactgtca
     4921 tacgtctcgc ttttgtattg aaatttcttc gattagagat acttattact gttcaaaagc
     4981 ttctttgaaa cggtgaatca attcattgac tacaggtgat aaaatccgat tctttttcca
     5041 gactagcatg cagttcgttt caatcattgg gtcaagcgga acgaatgtca ctcgctttga
     5101 atgatgactt acagcacctt ctatgactaa agcagcacct acctgattct caattagcgc
     5161 aaatacattg aaaatcaaat tgtacgttcc tgtgatcagc aactgctcct tttttatgcc
     5221 taaccagtca gcaaacattc gctgtatttc tggacgcttt gagatcaaaa gaggtacatt
     5281 cgcaaagtct tcttttgtta tcacgtcttt ttttgctaaa acagaatttt ctaaaatgag
     5341 caatccccat ttttcctttc ttggtaacaa aatcgtttcg tatttctctg tatctactgg
     5401 atctagcaaa atcgctaaat ctaacaggct tttttctagt cactccgtga tatcatcact
     5461 tgttccgctg tggatatgaa attgaacgct gggataatca cggatcaact tttctagtaa
     5521 tagtgccaat gtattcgaac tatcagcttc cacacagccg atcgtaaatc ggccgctgaa
     5581 taattgtttt tttctgttct cgaattcttg agtggtttga ttcgttaaat ctaaaatttc
     5641 ttctgctcgg cttttttaga aaataacctg cttctgtcaa gatcattttg cggttttcgc
     5701 gtacaaacag ttctgttcct agttactctt ctaactcctt cagttgtcgg cttaaggttg
     5761 gttgtgtaag atgtagaact tctgcggctt gagagattgt tccttcttct gcaattgtcc
     5821 aaaaatattt tagtaagcgt aactccatag cgatgctcct tgattttttt acttgataca
     5881 ttccatttta tttctagata acacacgatc atatttcttg atttttcctt gtaaacgttc
     5941 caaacattct tgcatttcag caattttttt cgtcaaaagt tcactttctt caatcaaaag
     6001 cttacgccgc tcaaatacag ttgcttctcc ttcgctagat aggcgaatat attcaatcaa
     6061 agactcgatc gataatccgg catttcgcat acagatcgta aagtcgaccc attttaggtc
     6121 ttcttctgta taatcacgga ttccgccttt tgtccgatta actggtggaa tcaacccgat
     6181 tcgttcataa tagcgcaatg tatcggccga aatgcccttt tcttcactga cttgtttgat
     6241 attcatctga tcactctttc tcttaatttc ttgccacttt acttatgtat tttatttatt
     6301 ctacaacttt aagtgtactc caagtcaata ctcatttcta ttaaaactaa gctggattat
     6361 ctatatcggt tgtttgtgta ttatttcaaa taaaaaagtc ttgttttttt attctttttt
     6421 ggatatactt ttaacaattt agggaaattt taggaaaagg ggtataaaaa tgacaacgta
     6481 tcagcgaaag gtattagtat cgacatcggc gggaattgct ttagagaata tggatattat
     6541 gtttttagct ttttcattat cttcaatgat tacttctttt catattagtg gtacgcaagc
     6601 gggtttcatt tcaacgatca ctaatttggg gatgctcatt ggaggtattt tttttggcat
     6661 catagctgat aaatatggac gtgtgaaagt attttctcaa acggtccttc tgttttcgat
     6721 tgcttcttta ttgatgtatt ttgcttcaaa catctacttg gtttatctct ttcgctttat
     6781 cgcaggtgta ggagcgggag gagaatatgg ggcgtgtatg tccttgattt ccgaaagttt
     6841 ttcaaaaaaa caaattggac gagcttcttc ggttgctggt attggtgcgc aggtcggtgc
     6901 ggctttggct gcgattttag ctgctgtgat cattccaacg tttggttgga agatgttgta
     6961 tgtcgtaggt gtactgccgg tgttgatggt cttgttcatt cgtcgcggct tgactgaacc
     7021 aaaggaattc aaatctgtac aatctgccga aaagaaaacc aaacttagca gactgtttga
     7081 atcaaaacat cttgcttggc aaacatgtgg ccttagtatc atggtaactg tccaaattgc
     7141 cggctatttt gggttaatga attggctacc ttcaattatg caaaatcgat tagggctttc
     7201 ggtttctggg tcttcattgt ggatggtcag tactatttta ggcatgtctt tggggatgat
     7261 gacttttggc ataatcatgg ataaattggg gcctaaacta gccttttctt tgtttttaat
     7321 ttgttcatcc ttatctgtct atctacttgt gttagcccat agccagtgga gtttggtagc
     7381 agccgctgtg atagtcggct actttatcaa tggcatgtat ggtggatatg gcgcagtgat
     7441 tagtagtttg tatccaacag aaatccgcgc gacggcgaat aatttcgtta tgaaccttgg
     7501 acgagctgtt ggtggttttt cttctatcgt catcggtttc ttgatggatc attatagttt
     7561 aactgccgta atcttgtttt tgagcggtat ttacctagtc agtctgctgg tcttgacaac
     7621 tcttactggt gttacagcat taagggaaag cttgcagcat tgatagttga gtctgtaaat
     7681 gacaagaaag aggtgtggaa aaagcttgca tctgcggtaa taagaccagc caaatcaaaa
     7741 acatgagaca ctgtttccgt ttggctggtc gtattacttg atgcagggca gctttttcaa
     7801 ctgctaattt ccttctatct ggcggcgact attctttgac gtccgtcatt tcaaagtact
     7861 ttactaataa cttagcataa cgaaaaactg tggatacact cgtatattga gcgtctgcat
     7921 aatcttccaa atttttctca ggatgttgat acatgaattc aatcaaatga taattatatg
     7981 attttctgta gaaatgaaga taaataatgt agattgggaa gttctcctgc ttttccatag
     8041 aaaagcgccg attattctca ttcttcaaaa tgaccttatc aggatattgt tggaacaatt
     8101 cttctaaatc tgttagataa ttcaagatag acttacttga taccttcaat tcgttttgta
     8161 gttcttctat tgaacaccaa cgttctgttt caagcagtaa atgaatcatt ttaattttct
     8221 tttgagaaac ttttgttaaa aaagtctgca tattttctcc tcctgtatct actttactat
     8281 actacataca agaaaaaaac ggatacaaat atcatattgt cacaccgtca atagtgcata
     8341 aacctgttat tatttctctt tttttcctaa gtattctatt g
//
LOCUS       DACGDM010000105         8321 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.111, whole genome shotgun sequence.
ACCESSION   DACGDM010000105 DACGDM010000000
VERSION     DACGDM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.111"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..409
                     /locus_tag="IXR05_002456"
     CDS             <1..409
                     /locus_tag="IXR05_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4260924.1"
                     /translation="SLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILD
                     NAIEASIESQDRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLG
                     LSSIEEINKKNPNMFVNYQNDPYQFTTQVILLF"
     gene            424..1176
                     /locus_tag="IXR05_002457"
     CDS             424..1176
                     /locus_tag="IXR05_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260925.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(1879..2094)
                     /locus_tag="IXR05_002458"
     CDS             complement(1879..2094)
                     /locus_tag="IXR05_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAQ4260926.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(2113..2349)
                     /locus_tag="IXR05_002459"
     CDS             complement(2113..2349)
                     /locus_tag="IXR05_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAQ4260927.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            2607..4760
                     /locus_tag="IXR05_002460"
     CDS             2607..4760
                     /locus_tag="IXR05_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HAQ4260928.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGE
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            4729..6144
                     /locus_tag="IXR05_002461"
     CDS             4729..6144
                     /locus_tag="IXR05_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAQ4260929.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            6177..7211
                     /gene="sppA"
                     /locus_tag="IXR05_002462"
     CDS             6177..7211
                     /gene="sppA"
                     /locus_tag="IXR05_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAQ4260930.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            7213..7734
                     /locus_tag="IXR05_002463"
     CDS             7213..7734
                     /locus_tag="IXR05_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAQ4260931.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            7731..8117
                     /locus_tag="IXR05_002464"
     CDS             7731..8117
                     /locus_tag="IXR05_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAQ4260932.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
BASE COUNT         2962 a         1198 c         1498 g         2663 t
ORIGIN      
        1 aagtttgttg atagcgaagc tataccaagc aaataacaat aagatttgtt gtaaattcga
       61 atgtccaagt actattattg aagttcctgt tccaatattt gactgtatta gggtgcttgg
      121 aattattctc gataatgcaa ttgaagcatc tatagagagt caagatagag aactgtctct
      181 agctatttac cgagatgata aacagataga aatttcgata tcgaatagtt gtagagagat
      241 actactctct atagatactc taatgaaaaa aggaataaca acaaaaaagg gacatcaagg
      301 gttaggttta tctagtatag aggaaatcaa taaaaagaat cccaatatgt ttgtgaacta
      361 tcaaaacgat ccgtatcaat ttactactca agttattttg ttgttttgag ggaaggagga
      421 tttatgagtt atccaataat attatgtgaa gatcaaatta tacaattaaa tcagttagaa
      481 cgaattattg ataatttcat tctttttcac gataaagtat ttaagatagt attgaaaaca
      541 caaagtccgt tagaagttaa aaaatacctc aaacaattcc gaccaaagca aggaatatat
      601 ttcttagata ttgatttaaa tcatgaagtt aacggtatag aattagcaga agtaatcaga
      661 aaatatgatg ttcaagcaaa aatcattttt acaactactc atgatgagat gttacccgta
      721 acaataaaaa gaagagttga aacgttagga tttgtaacaa aagatcaaac actagatgag
      781 tatcgaaacg agattgttga gttattgtta ttagcgcaag aaaggataga tgcaacaaaa
      841 caggttacga atcaagcatt tgttttttcc ataggttctc aaacatttac ttttgatata
      901 aatgacattt attttgtaga agcttcaaaa ttaccacata gattatcatt gtgtactaaa
      961 gatgggcagt acgaatttta tggaagaatt agtgagcttg aaaagaaata tcctatgtta
     1021 acaagaatta gtcgagcgtg tttagtaaat atctttaacg ttaaagaaat agattttaaa
     1081 aaacgttcac tatattttga ttcagagttg gccagaaact ttactttagg gaaagcacaa
     1141 aaaattaagg agaagttgaa agaaagcact gtttagtggt tttttcttta gggagattgc
     1201 atttttctaa taaaatagat tccttcacta gtgcaaattt ttctgaatcc tattaaagtt
     1261 gtaccaattt ttatagctgt tattagttac gtgcataaca gcaatattag ttactggagg
     1321 aatatttcta tggtctggaa ccaaaaaagg gccaaatgaa tagttctttt cttgttttta
     1381 ttaagtacca taaaggggaa ttaaaattaa atgtatggtg gaagatgcga aagatttggc
     1441 aaattctact aatttttaga aagtgttttt cattttttag ttaaaaaatt tgtcctgtca
     1501 agtgcaatcc tatgattgta cttgatagga tttgagataa ttactttcct gtttttataa
     1561 atttaacttg caggaacagg ctttaatgca catccgacaa gtacattacc aatacctcct
     1621 gtaacggccg aaataggtcc tcctgcagca ccaactacag cgctgcaagt ccttttgtaa
     1681 aaatatctct accattacat ttccaaagaa tttttatctg actttaataa aagataaaaa
     1741 tttaatataa ttataaaaac tagcacaaga agctttagta aaaagttctg tccattccaa
     1801 acttttgaaa agataaagaa catacctatg ttcgtaatcg acacaaacca atcttgaggt
     1861 ttgatatttt ttaattgttt acgcaccggt ccacatgctg aatccagcac ctaataaagc
     1921 tccacctaca ccacaagcag ctattgcata aggtcctccg gctgaacaaa gttttactcc
     1981 tgctgttgcc ccagaaaaag tagtgcctaa aactcccacg gcactcccac cttgaatatt
     2041 tttcaactct tctgaagata atataaatgt tgtttttgtg tttttaatat gcatactact
     2101 tattctcctt ttttattttt ttcgagcatc ccagccagct gcagcacctc cagcgacagc
     2161 tccatataac cctccaacaa caccgcaagc tggtccgcaa attgctgttc ctaaacctgc
     2221 accacctact gcccctgtgg taagtccacc tacaacttgc cccaattttc cccaagcatt
     2281 attgcctcca ccaacagttt gtgcatttcc acaatactta gttcctttac attttgcatg
     2341 tttaaacacg cttctttaaa taatattttt tacggtgcta ctgtaacata cgtatttgat
     2401 taacagtaaa aatcttcctg aaacttatca agtttattct tgaatagtaa aatttccaaa
     2461 ataaatttga ttcaggaatg aaaaagttag tgttcaagaa ctgttttcaa agtttttgtg
     2521 gaattatgag acaatatttt cactgtatta aagctatatt gagaattttt ctataaaaat
     2581 tttttagaag gagttgtgtt agataagtga taaaatcatt tccttttgtg cagcaacaag
     2641 atgaaaaaga ttgtggtgtt gcttgccttt cgatgatttt aaaatatttt aaaactgata
     2701 tcccgattca taaattacgg gacctatctg ggactgattt agagggtact tcagcatttg
     2761 gattgaaaaa gacatttgaa aaattgtctt ttgattgtat ggctattcaa gcagatagtg
     2821 agatctggaa agaaagagat cttatcttac cattaattgc acatatattg gttgataaca
     2881 gctatatgca ctacgttgta atttataaaa cgaagggaaa cgtactatgg attgcagatc
     2941 ccgctaatgg aaaaaataga aaaacgattg aagcgtttca aaaagaatgg acaggtattc
     3001 ttttattacc tatgcctaga gaaacttata ttcctattaa agaaaaagta gctggattaa
     3061 gttctttttt gcctataatt tggaaacaaa aaggattagt attccacatc gttttagcat
     3121 cgattttcat tacgtttttt ggcataggaa gctcatatta ttttcaaggt attcttgatt
     3181 ttttcatccc taatcaagca cgttcaactt taaatataat ttccattggc ttgatcgctg
     3241 tctatttatt tcgggtattg tttgaatata gtcgtagtta tcttcttatt attttaggac
     3301 agcgaatgag tatggcaatt atgcttcagt atttcaaaca tgtgttaact ttaccaatga
     3361 atttttttgc tacgagaaaa tcaggggaaa ttatttctcg ttttcttgat gccagtaaga
     3421 ttattgatgc tttagcaagt gctacgttat caatattttt agatattggt atggtgttgc
     3481 ttgttggggt tacgttagct attcagaata gtacgttgtt tttaatcact ctatgctctt
     3541 tgccttttta tgtagttgca atattcgctt tcgtgaaaag ctatgaaaaa tcgaacaggg
     3601 aagaaatggc agccggtgca gctgtaaatt ctagtatcat agaaagtctt aaaggaatag
     3661 aaacaattaa agcatatagc ggtgaagaga aagtatataa ccgtatagac catgaatttg
     3721 ttaaattaat gaaaaaatca tttcgtacgg ttacgcttga taatattcaa caaggaatta
     3781 aacatttgat tcaattaatt agcagtgcat taattttatg gctaggttct tattttgtta
     3841 tggataatag aattagtcta ggtcaactta tcacatacaa tgctttacta gtatttttga
     3901 cagatccttt acaaaacatt attaatttac aagtgaaaat gcaaacggct caagttgcaa
     3961 ataatcgttt aaatgaaatt ttcgcgattg attcagaaaa atcgaaccag tcttttgaat
     4021 atatgctttc tgaacaatta tttcaacaag atatcactgt aaaaaacgtt tcattctcgt
     4081 atagcatgaa ggccccaacg ttgaacgaaa tttcatgtac aattccttcg cacagtaaaa
     4141 cggctatagt tggagttagt ggttctggaa aatcaactct tgcaaagtta tttgttcgtt
     4201 tttatgaagc atcagaagga tcgatccatt atggaaacat taatcactta gacattcctt
     4261 ttcagatatt acgcgatcga gtgacatatt tgcctcaaga gtcatttttc tttagtggaa
     4321 caatcattga gaatcttata ttcggtttag atagcccacc aagtttcgaa caaataatag
     4381 aagtttgtga gatagtccaa ctaaatgaat ttattaatca acagccatta cgttacgaga
     4441 cattgttgga agaaggtgga aataatcttt caggagagca acgacaacga ttagccttag
     4501 cacgggcttt attaaaaaat ccggacatat taattttaga tgaagcaact agtggattag
     4561 ataccttgtt agaacatgca attatgaatt atctcctcaa tttaaaagaa aaaacgatta
     4621 tttttattgc gcatcattta ccaatagcaa aagcatgtga tcaaatttta gttctccatg
     4681 aagggcattt ggtagaaaaa ggaacgcacg atgaacttcg ttttgccgat ggtatctatc
     4741 aaaaattatg ggaaatctag gagagggaaa caatttatgc agaataataa ttggttcgaa
     4801 cattctagta tctatactaa acaacatcat agcttctacc gttgggtgtt ataccctgta
     4861 attctttttt tatgtattat tggattgttt ttaacctttg ctaaaaaaga ggttgttatt
     4921 cggacaacgg ctcaattgaa ccccgaaaaa atagagaagt tacaagtgcc attagaagct
     4981 aaaataatgg aaaacttcct aaaagaaaat caatttgttc ataaggacga tgtgttggtt
     5041 agattggatt gttctttaat agagaatgaa aaggctcaga tagaacaaga aaaccaacgt
     5101 attactcaac aaataaagat ggctcagcta tttattgaaa gtataagtaa aggaaaaaat
     5161 ttgttttcaa cggatgacag ttttggctac agtaatcaat taaagagcat gttgtcagaa
     5221 aaagaatcac tccgctacgc tttgaagcaa agtgaattaa atgatcaaaa gcaattagaa
     5281 gtatacgaaa agacaaaaag acaactagaa aaacaaattg agagttcaga tagtaaatta
     5341 caagaatggc aacaagtaca ggtagcttgg agtaataatc aatcattaaa agatttttca
     5401 aaagaaatga tggcaaacta tgagaattgg caagaacaac taaataatgt ttctgatgat
     5461 caaaaaaatc aagtgaaact gacaatttca gcaagcataa atgaacaaat tgagcaacta
     5521 aaaaaagaag tagaacagta tcagtcagaa aaagctaaat tagttaaacc aactacttct
     5581 gagaatgaca gaattagtca aacggaaaaa ggaaagcaag agctagaaca agcaataaca
     5641 actgtaaaac aaacagttac agagctaaat gaaaaacaag agaagaacca gtcagttatc
     5701 aaaagtttgg acgatcaact ttcaaaagga atactaaaag ctcctgtatc tggaacggtt
     5761 catttaaatg aagaaacaaa gggacaagca gaactagcca aaggaacagt gcttgcagaa
     5821 atttatccga tccacgaaaa atcaaaaatg aaatttacag cacttttacc tgcgaatgaa
     5881 agtacctata ttaaagaagg gatgaaggtt cattttaaat tggatcaaaa aggtggggct
     5941 ccgattacga tcgacggaac tttagatgaa atttcagaaa attctactgc cactgagaaa
     6001 ggtgtttttt atgcagtgaa aggaacgtta aaaacaactc aatcgtttcc gtttcgttat
     6061 ggattaactg gagagttgtc tttaattgta ggagaaaaaa catattggca acaaattgtc
     6121 gatgtgtttc taaataaaaa ataattattt ttactaagaa tataggagga gtttatatga
     6181 ataaaagaag atggattgct gtgggagtag cgtgcggatt attgttacta tccattatcg
     6241 tcgcgctaat tccaggaaaa gataaagagg aagcatcaaa tacaacccta acaggaataa
     6301 ataagatttt ttacggatct aacgaaatca cagaagaaac gttagaagaa ggcgcatcaa
     6361 ataaaaagat tgtcaaacta tccgtcaatg gagttattgc agatacaggt gaaagcaatc
     6421 tttttagtag ggaacaatat aaccatcaga attttttaac acagctaaag aaaattcaag
     6481 aagacaaagc ggttaaggga gtgttattag aagtaaattc acctggggga ggaatatatg
     6541 aaagtgctga gattgctaaa gaaatggcaa aaattaaaaa gctagatatt cctatctata
     6601 ctgcatttaa aaatacagcg gcaagtggag ggtactacat ttctgctggt tcagataaaa
     6661 tatttgctac ggaagaaaca acaactggat caattggtgt cattatttct ggtttaaatt
     6721 attctggctt attagaaaaa cttggcgtaa ctgatgcgac gtataaaagt ggtgcattaa
     6781 aagatatgat gtcacctcaa cacaaacctt cagaggaaga gaataaagtt atacaggaat
     6841 ttgtgatgag tgcttatgat cgttttgtca atgttgtagc aaaaggaaga aatatggata
     6901 ctaatgcagt gaaagaactt gcggatggaa gaatttatga tggtaaccaa gcagtagaaa
     6961 atgggttggt ggatcaaatt ggttactctg aagatgcatt agattcccta aaaaaagaga
     7021 agaaattaac tgatgcgacg gttatagaat ataaaaatga cacaactggc tttgcttctt
     7081 cttggttagg taataagatt gctgaatggc aagggctaaa ggcaactaca tcagatcgtg
     7141 taatttcagt ttttgaaaaa cttggatttt ctgatactcc aaaaccaatg tattactatg
     7201 gagggctata aaatgaataa gaagagtggc attgaaactt tgcctaatta tgtatttgcg
     7261 ggattttggt tacgattttt tgcttttctt attgatttaa tttgtattag catcatcacc
     7321 catgctacta taggtctctt ttacaaaatc atgggactgg aatctgacaa atccattatt
     7381 actttttatg gtatagcgtc attagctatt tatttaacct attttgtact tttgactaag
     7441 ctgaattcag gacaaacaat tgggaaaatg atttttggga taagagtagt gagctttgag
     7501 gaaaaagagc taagttggca aactatcttt attcgtgagt gtatatgtag gtttatatta
     7561 aaaaattttg tatttcaaat tgggtatttg gtggctgctt tcacgcccaa gaaacaacat
     7621 attggggatt atttttctaa cacgtcagtg gttgttattc gttcattaga agctattaac
     7681 tatggtcaaa aaatttctaa ttctaaaaca cttaatctgg agagaattaa atgaataaga
     7741 gaaaaacaga gtttattttg attttaatta gtggaataac agggatttta tgtagtcttt
     7801 tagcattgat gggtggtatg tttctatctt ctattgattc aactacttta aatactacag
     7861 aactaaccag taaggatata gatatgttag tcaatctaag cgggaatgtt gttttatttg
     7921 gaggaattac cctagttttt tcgataatga ttttcataat aggtttttta gtaagaaaaa
     7981 atcaaaaaac agtggtctat ggtattagtt tactcatttt atctattatt ccattttttc
     8041 ttttaacatt attgtgggta attcctggag ttttaggtat tattgcggga ttgatgcttc
     8101 taataagaaa atcttaatta ggcaatgtgt agacaacgtg aaacgattaa tcaattaaaa
     8161 gctaaatacg ttttgagaaa tgataacttg tagtcgatgg aagacatgta gataaaaaaa
     8221 ctacgtgtct tttatttatt ctaatttttt cgaaaaaaag acactctctg attgttgtat
     8281 taatggaaaa ggggaaagca gcaagtaaat ttagtttttc t
//
LOCUS       DACGDM010000106         8205 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.112, whole genome shotgun sequence.
ACCESSION   DACGDM010000106 DACGDM010000000
VERSION     DACGDM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.112"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(487..2118)
                     /locus_tag="IXR05_002465"
     CDS             complement(487..2118)
                     /locus_tag="IXR05_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAQ4260933.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(2132..3805)
                     /locus_tag="IXR05_002466"
     CDS             complement(2132..3805)
                     /locus_tag="IXR05_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4260934.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            complement(3818..4135)
                     /locus_tag="IXR05_002467"
     CDS             complement(3818..4135)
                     /locus_tag="IXR05_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4260935.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            complement(4160..5560)
                     /gene="lacG"
                     /locus_tag="IXR05_002468"
     CDS             complement(4160..5560)
                     /gene="lacG"
                     /locus_tag="IXR05_002468"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAQ4260936.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            5797..6582
                     /locus_tag="IXR05_002469"
     CDS             5797..6582
                     /locus_tag="IXR05_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4260937.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            6585..7277
                     /locus_tag="IXR05_002470"
     CDS             6585..7277
                     /locus_tag="IXR05_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4260938.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7551..7922)
                     /locus_tag="IXR05_002471"
     CDS             complement(7551..7922)
                     /locus_tag="IXR05_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAQ4260939.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
BASE COUNT         2526 a         1806 c         1405 g         2468 t
ORIGIN      
        1 ccaacataat atggaggggg aatccctata aatcaacatt cttcaatagc taaaatgctt
       61 gattttcatt aaaaataaga tggttcccta ccaaaagaga ctataatata agttaatttg
      121 tttcattctt atcataaaaa gaagttctcg aaaaacgaac tgttttccga gaactttttt
      181 ctatccatct aagtgctcaa atcatattca cgacggaatt ctaaggttac cctttcttaa
      241 acaaacttta tgttatctgc acaacttttt gcaatttttt cattgcttct tacgaaatcg
      301 ttgaactctc tttagcataa tacaaagtgt agatgaagtc tggtgcttta ctcgttttgg
      361 taaaaatgac tggaaatcgt ttctggttat ttttggcaaa ggcgaggtgc aggttcgatt
      421 cctgccttct acgctaacga tgtggctgaa gggaacctcc gatcttgaat cgaaacgatc
      481 cgcagtctat tgtttcacca atgaaacaaa atcaacgttc gtccaagcat ttcctgaagc
      541 cttgctataa accccaattt cacaaacacc tgttgtaatt ggaatgtctt tgattgtaat
      601 ttttgtccat tcacttgttt taacaaccgc agtatttagt tccgctccac cataattttt
      661 gatatataac tgattagtat caaactctcc cccagacatt acataggcac tcaatgtgta
      721 agttcctttg cttatgccac taacattttg ataagctgat gcctcgtatg cttgatcctg
      781 ccaaaaagtt agtttgtagt ccccaaaaaa agtgcccgct tccgttttga tcgtaccctt
      841 agcggttcct tgttgaaacc aggtttgcca attggaagga ctggtcgttg gtccatcgct
      901 ttcgaaactt gcatttttaa ctagatttat ttgcgcccct gcttgtttaa acgcacgcaa
      961 gcttggcaag gcgtttccag caaaatcaaa catcgcttgg ttgtcccatt cgtttcccat
     1021 agtggattga acactgagat aattcatacc tgcttgtgtt gcccaactca catttccgtt
     1081 gtaccaaaga ggttcccaat agaagaagcc cgccccgcga ttattcggta ctgcctgaat
     1141 ccgatcggca agatccagca aatactctgc ttgtcctgtc ggtgttggtt catatccccc
     1201 cgcagctgct tcggcttcac caaaagcatt tggcatagta tcggcattcg ctgttgtatg
     1261 cccataagct gtttcaacta cgatcacttc tttaccatac cgttggctga tcgcattcat
     1321 attggtttga agttcattca ttgaaccgtg ccaatacgga taatacgaca ctccaattaa
     1381 atcaaatgac acacctcgac tcgtgatttc atcaaaccac caagtaaatg ctcctgtatc
     1441 gccaccatca gctaagtgga gcattactgg agttgtttta ggttgagtgt ctcgaacagc
     1501 ttggatacca gacttcaaaa aagcagccaa tcgatcaaat tctcccccgc cttctcccca
     1561 agacttgcca taaggccaga gcattccgct attcagttca ttgccgatct gaaccatatc
     1621 aggataaacg tccagctgct tcatttccga cagaacgttc tttgtatagt cgtacaatgc
     1681 cgtattcatt tcttcaaagg tcagaccttg ccatgcttta ggaagattct gtttcccagg
     1741 atcaacccaa aaatcactgt agtgaaaatc cagcagcacc ttaagtccca gattttttgc
     1801 tcgttttgca aggtcaatcg tcgtttccag atcatttgtc cctgctccat aactttctcc
     1861 attactatta taaggatcct gccacaaacg cagtcgaaca tagttgacac cattattttt
     1921 taaaatctct aaggcatctt ttgaaatatc gtcttcataa tattttgcac cagatttttc
     1981 catatctgac aggatcgaaa tatctgctcc gcgaataaat tcgctggcag atgcttcaac
     2041 agtttttgaa acagccccca aagcccctaa cacagctgca aataaaacag ctttacgcaa
     2101 ccaaattccc attttcatta tggctcctcc tttattgaaa ttggttcaga ataaactgaa
     2161 cagctttttc aggatctctc gttaatccga tatattctgc tccttttgtc gcaaccagct
     2221 tgattcctaa gcgatcggtg tcttctttga tatcatcata gtaagaattg acttgcggtg
     2281 ctaagaccac catatcaaaa tcctgcagca tttcgtaatg agaaccataa gcacccgcca
     2341 ttgcactgat cggtgctttc gattcagatg cacctttttt taaagcatta gctaacatcg
     2401 cacttgtccc tgcgccagca caaagtacca acacattgat ttctttattt gcatcgctga
     2461 taacttgact cgctgccaca ggtacttcct cacgtacatc ggcagaagca ccttcctcgg
     2521 ttgcgatcac ctctgctttt tgtgcttctt tctctactaa gacagcatcg tatgctttgc
     2581 aaaatggtag atagatcagg aagtcaacga cgattagaac cgctgctaga acaaaagcta
     2641 agatacccat gcccgttcct agaaccaaac cgatcggtgc tggagttgcc caaggcaaaa
     2701 cgtacataaa gctgttcatg cccaatacat cgacaaaaaa cttgaacagg caaacgttta
     2761 caacaggtgt taacaaaaat ggaataaaaa aataagggtt caaaatcatg ggtgccgcaa
     2821 atagcaatgg ttcgttgaca gcgaaactta ctggaataaa ggaagctttc ccaactgcct
     2881 tcaactgctt agacttagca aagagtagga agataaaagg aacaaccaat gttgccccag
     2941 ttcctcccat agttcctaca aaattcccta aacccaccgt cagtacttta gaagcttgtt
     3001 caccggaatt gaacaattgc agattggttt ccacattggc atagataatt gccgcaattg
     3061 ccggctccac gatcgacggt ccatgaacac cgacaaacca aaacagcgcc atcgctcccc
     3121 agataatagc gattcctaag tacccgtcag ctgctgtaaa tagcggctgc agcaccgtaa
     3181 tgattgcttc tgcaaatgag atttggaaga tttgtcgaat gcctaaatca attaaaacgg
     3241 ccgcaaatac tgaaaaagag aaaggaaaaa tatctcggaa ggtttgcgaa atcgttccag
     3301 gaacttcttt aggcatttta atggtaatat ctttcagcac acaaaactta tataaattaa
     3361 ctgttaaaaa tgcagcgaca aaggaagcca gtagtccctt tgtccccata tattccgttg
     3421 aaaatccacc ttcaatcgga gagacgctta acaacaggaa acttaccaca gaggccagca
     3481 tcacagaggt ggtgttgatt actttgtttt tcggtaagcg acgattcatc gaatcagcca
     3541 agcagcgagc agtggttgct gaaacgagta accctacaac acccatcgaa taattataga
     3601 ctttccatag ccatgtggag acagattcag gccattggta accaaaaatc tcaggaaccg
     3661 cagcaatcaa aatgaaaatg cttgaaaata aaatagctgg catcgctgtt aaaaatccgt
     3721 cacgaacggc tcctaaataa ctattacgtg agattttttc aaaaaatggt ttcccttttt
     3781 cgatttgttt aatgattcca tccatagcgt tcttctccta tccttgattc tgtctgtaca
     3841 gtacaataaa gtcttgaatc agatctctca gcaataaagt ggtcattaaa tgatcctgcc
     3901 catggataaa aatgaatccc atctccatct ctttcccaga tgcttcttcc gctaaaattt
     3961 ttgtttgcga attatgtgca agggttaaat tttcgtcggc ttctttcaac gccgaatcaa
     4021 catgttcaaa gtttccttgt cttacttctt tcaataattt caataatgta ctgcgagcgt
     4081 cgcctgaata tgcaacgatc tcaaaaccaa gcatttgtaa ttcctcttta ttcatctttt
     4141 cttcctccat tatcacttat taaataatcg ttttggtttc actgaccaac ttgtaccagt
     4201 aagctgattc ttttgggtaa cgcttctggg tttcaaaatc aacataaaac aagccatacc
     4261 ttttgttata cccatttgtc catgagaaaa gatccataag cgaccacaaa aaatacccct
     4321 tcacatttac cccggctgtt atcgccttgc ttaaggattc caaatagact ctcaaatagt
     4381 cgattctcgg ctgatccata ataatgccat cttcaaactg atctttatac cccatcccgt
     4441 tctcagtgat atagattttg ttgtaatgtg ggtaatcgct tttaattcgc agcaacaagt
     4501 catatagacc ttctggataa atcagccagt cccaatcagt tcgaggaatt ccttctttat
     4561 aaatacgttc tccgattccc ttcactttat aaacagaggt ccctttttca cccgtaccgt
     4621 tatgatggat tgcattttct ccatcgtaag ctttgacaaa atggcattgg tagtgattga
     4681 tccctaagta gtcattacgc gtggatgctt ttttcaattc aacgaaatct tcttcaggaa
     4741 aatgatagct ggcctgattt gcttcacata tctcatcaag agcagtcaag gtttcagttg
     4801 aataatagcc taaataggta gcatctaata agaaacggat cgacaatgca tcgtctaaaa
     4861 aggcagcatg cttatcttcc ggcgcgtctg ttgccgcata tttcgtctct aatgagtgaa
     4921 ctacaccaat ttcacccgga agttcgtttt ctttgaaata gttcactaca cgggcatgag
     4981 caaccatcat attatgaaga caggcgacga tctttgtaaa atcatatttg attcctggtg
     5041 ggaaaacacc taacaaatat tgattggttg caactggata gatttcatta aaggtactcc
     5101 acaccttgac ttctttgaat tcatgaaaac aaaaaatggc ataggaaaca aatgcttcta
     5161 ttgtttctcg attcaaaaaa tctccatggt caaacaaacg tttaggggta tcaaaatgat
     5221 gcaacgtcac aaacggcgtt acgtttcttt tcttacattc ttcgaacaca cgatgataaa
     5281 aagcgattcc ttctggattt ggtttcccag ctccatcagg aaaaatgcgg ctccaagcaa
     5341 tggataatct tagaccattt acaccaaaac gttcacacaa ttcaatgtcc tttgcatatt
     5401 gatgataaaa atcacttgcc ggatcgggac tgaatcgccc ttgttcctct aaaaagtcat
     5461 cccaagcaac agcgcctttg ccaccttcct tagtggctcc ttcaacctga taggctgctg
     5521 tggctccgcc aaaaataaaa tcttctggta atttaagcat gtacatctct cctcaaatct
     5581 ataatcagtt ttcgctcttt ctaactgatt gcattgtaaa cgcatccaaa acatttgtca
     5641 acaaaaacaa acacaaataa tcataaaaac cagaaaacag caataaaatc tattgtaaca
     5701 aacataaaaa ccaccctaaa tgtttacttt tgttcgaatt agattgactg ttgtccgttt
     5761 atatgataga ttatccttaa attagaggtg aagacaatgt tgaaaaaaga aagattgctt
     5821 actatcgtag aaatggtcaa taaaaaagga atccttaccg ttaatgaaat catcaatcaa
     5881 ttagatgttt ctgatatgac cgttcgcaga gatttagatg aattagaaaa atcgggcaag
     5941 ctgctgcgtg tccatggagg ggctcaaagt ctttcctaca ctttagatca agaactttct
     6001 cacactgaaa aagccactct gcagattcaa gaaaaaaaag aaattgctgc cacagcagcc
     6061 tccttgattc acgagggaga aacgattttc ttaggaccag gtacaacaat cgaactattg
     6121 gcgacgcatt tactgaacaa gaaaattcgg atcattacaa ataattatcc agtttttgat
     6181 attcttgctc aagcagatgg accagaaatt ctactgattg gcggtgattt ccggaaaaat
     6241 accggcgcat ttgtcggacc gatcaccaac gacaatttaa gaagactaaa gtttacaaaa
     6301 gcatttatca gttcaaatgg cgttcacaac gaagcgatct ctacttacag taccgaagaa
     6361 ggagaagcac agcagatcgc tctaaataat tcccgtaaga aatatctact cgttgataat
     6421 aaaaaattca atcgagatga tttttatgtg ttttataatt tgcatgattt cgatctgctc
     6481 attacggatc gccagatctc gcgggaggtt caagagcact atgcacaata tgtcgatctg
     6541 caaattgctg attcaaccga aaataccact ataggagcgt aactatgaaa gggattatat
     6601 ttgatttcaa cggaacaatg tttttggact ctcatctgca tgaagctgct tggctgcata
     6661 tgatacatga tcatacaaaa gatggtttat cagacgagga tattttaaaa aatattcatg
     6721 gtcggacgaa tacggagatt ttgaaacatt tcatttcaga gcatttgacc gcctctgaga
     6781 tcgccgtatt gtcagaagaa aaagaaagct attatcgtat gctttgcttg caaaatgaaa
     6841 acgagcttca gttgacaaaa gggcttgaag cgactcttga ccagctgact gaccaacaga
     6901 ttccattaac gattgccacg gctactgtca aagagaatgt tgctttttat tttgatattt
     6961 tcgatttagc ccgctggttt gactgggaca agattgtcta tgacgacggc tctttccctg
     7021 ggaaaccgca accggatatt tttcttaaag cggcagacaa actgagctta gctccggctg
     7081 attgtcttgt tatcgaagat gcttactcag gattacttgc tgccaaacgt gcggggatcg
     7141 gaacaattat tgcaattgat ccattcggta aaaacaaaac agtatttgaa caggcacagc
     7201 taaataaaga tggaaccatc aaagatttta ctggtttttg gacagagcac ctgtctgcca
     7261 catccgttaa ttcttaaacg attcaactaa ctaccaaaga aaagcaactg aaatgcacac
     7321 ctccttttat aaaaaactgc cagtgaaacg acatgaaaga tacactgcta tatccttagt
     7381 gaaatatagc agtgtatctt tgactttttc attcttttaa ccatatgacg cgttcatctc
     7441 tatctataat taacattaaa aatagtgttt tcacattatt tctcaaacca atcttaaaaa
     7501 tcatcaggag tacttttttg atatactttt attaatgctg ggcgtaatgg ttaaaagatt
     7561 tccactagtt cctctccacc aagctgagtt gaaaaatgct tatctgtaaa caacatagac
     7621 aaagaggaaa taaacgtttc cgtatctttc tctgtcccaa ggatattaat taattttcct
     7681 actaggtaag tatcattaaa cttaagatct gccttcacat caaaagtttt gataaaagct
     7741 tttatcatgc gtacaatttt gtctttatcg ccataattga tttcaccact catatcaata
     7801 tagtcactaa tccctgaaga aataatggca actgcttctt ctttcgcctt atcagataat
     7861 tcatttaatg actgggattg attgatgact tcttgagttt tatctgttac gtaatctctc
     7921 attatcctat cggcatactc cgcaaagtaa tcttgaaaaa attcttctac agggtaacca
     7981 acttcgtttt cccaaccagg agaaatttca ttatcagtac ttattaaatc tattaaaaac
     8041 caacccgttc tctgagtgtt gattctataa tatttttaat ttcctatata aatcaaaaat
     8101 attatagaat caataagcta attaagaaac aaactttaga aactctagaa gaacttctga
     8161 atttatatag aagtgtgtag ctacttacta aatatacaaa agtta
//
LOCUS       DACGDM010000107         8155 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.113, whole genome shotgun sequence.
ACCESSION   DACGDM010000107 DACGDM010000000
VERSION     DACGDM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.113"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..721)
                     /locus_tag="IXR05_002472"
     CDS             complement(<1..721)
                     /locus_tag="IXR05_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4260940.1"
                     /translation="MNSWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVPSINRLKHWVSVTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNRQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAIQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDILFK"
     gene            complement(732..2108)
                     /locus_tag="IXR05_002473"
     CDS             complement(732..2108)
                     /locus_tag="IXR05_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4260941.1"
                     /translation="MERKFGLRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     TVGTLFLVARFIDAVTDITMGRIVDGSKPSKTGKFKPWILRMSGPVALASFLMYQTSM
                     ASASMSIKVIYMYVTYILWGSIFYTSINIPYGSMASAITSVAEERTALSTFRSIGATL
                     AGMFIGVLTPIFIYTRDSSGAQIVRGGSTFTIVAGVFSVCAVICYVICYKLTVERVKS
                     DESQLKVSLLKSLKGLAKNRALLSIIAAAIFLLLAQLLTMSMNNYVFPDYYNNAQGIV
                     LMNFINPILMLVLVSPVSLIFSKKYGKKELASVGMFFSAIVYLLLFLIKPSNMYVFLV
                     LTSVGYMGLGIFNTVIWANITDVIDDQEVKSGQREDGTIYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLAKVQSGEVLQKLYNSSTLIPAVCFFVVGLILFFVYPLSKEKVLENY
                     NLLNQKHN"
     gene            complement(2237..2884)
                     /locus_tag="IXR05_002474"
     CDS             complement(2237..2884)
                     /locus_tag="IXR05_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4260942.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINAITAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVEIIKLFPGSAFGPSVVKTYQAPLPYVNIMP
                     TGGVSLDNLEEWFEAGVVAVGVGGNLLAPVEKGDFEEVTRIASKYIDKFYEIKNY"
     gene            complement(2968..4395)
                     /gene="uxaC"
                     /locus_tag="IXR05_002475"
     CDS             complement(2968..4395)
                     /gene="uxaC"
                     /locus_tag="IXR05_002475"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4260943.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAEHQPIIDYHCHLDPACLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGAGNDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLKMMDVKAICTTDD
                     PTDDLRYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAGIPIKNFNGL
                     KQALSQRVDYFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIESRK"
     gene            complement(4469..5548)
                     /gene="uxuA"
                     /locus_tag="IXR05_002476"
     CDS             complement(4469..5548)
                     /gene="uxuA"
                     /locus_tag="IXR05_002476"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4260944.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKALKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYHLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEAKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLEWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(5551..7182)
                     /locus_tag="IXR05_002477"
     CDS             complement(5551..7182)
                     /locus_tag="IXR05_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4260945.1"
                     /translation="MVLIKDWQDSIEGLNKMQVQLPYFNVEAVKQEGQKHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELESGVVVCETFDEEVVEKAYHDYNNDILEIVMGEDGEL
                     KKRLLAVTADSLYCNPKNITDYQRVVKYFEDPTLQFTTFTITEKGYSLKDSKGQFFSV
                     VEADIKSGPTNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFMIAE
                     AWQKKGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSESVKMDLLKAGFEDLDIIHTA
                     KNTNIAAFTNTEKVHYLVIEDSFPNGRPKLEAAGVIMTDRETVDKADIMKVTTCLNPL
                     HTALAITGCLLGYKSIQAEMQDDDLVGLIKGIGYVEGLPVVESPGVIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGKNFVPSPDPLLVELQEKFSVLKLGEQDPAKIHCAVQEILENKEIFGLDLYQ
                     VEIGKKIEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            7499..>8155
                     /locus_tag="IXR05_002478"
     CDS             7499..>8155
                     /locus_tag="IXR05_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4260946.1"
                     /translation="MTIKTSLQNQAYQSIRQQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRHQGLVDTIPQSGNYISLIDLDLAKNARFVREHLERQIMLECCAKMNNQ
                     KKQVLETIIAEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLEDNNTHLERF
                     RWLRVKTEGLKWEKIMEQHHQLFKALTMQDPEEANFLTSLHLHLMLDEQNVVLTTHPK
                     Y"
BASE COUNT         2629 a         1627 c         1097 g         2802 t
ORIGIN      
        1 atttaaataa aatatcagtt cttaagtttt cccatgattc tttttcttta ttaaccaaaa
       61 taggataaaa gaaaacttta ttcttatttg cagcttctag atcaccagga gaatcaccaa
      121 tcattaatat cttatccaaa tcacaaccat tttcaattac acttcgaata atgtcttctt
      181 tttttccttt atcttgacaa cacagttcat caactaagga taataattca tgtctttccc
      241 attcttcttg aatagcttcc ttattagctg agcttacaat aattatcttc ccatattttt
      301 tcagagcttt tatagtatct ctagcactta aaaagggttt atctaatcct ttagcttgac
      361 taatctgtcg attgacttct tccgaccatt ttaaagcttt taataaatcc tctgactgag
      421 agtattctat ttccctcttc aaagatggat tagacaattc ttttgttaca gatacccagt
      481 gctttaatcg attaatcgat ggtacatcat ttttttctaa tgttttaact aaacctaaaa
      541 atctgtttat tccacgagtc tctgaatata aattaatatt attccaatcc tgtaggaatt
      601 tttccctatg atgaacatca aaaatctctg cagcaattgg cccgaaaaag agattgtgtt
      661 tataagtcat tgtatccatg acacaaccat ctgaatcaat acaaaatatc caactgttca
      721 tgttttttct cctagttatg tttttgattt agcaaattat aattttctaa tactttttct
      781 ttagataatg gatatacgaa aaataaaatc aatcctacaa caaagaaaca aactgctgga
      841 atcaacgttg aagagttata cagcttttgt aaaacttctc cactttgtac ttttgctaac
      901 gaatcatacc ctattataga aagagtccaa cctccgacac cgccagctaa agcttgtcca
      961 atttttcggg caaaagaata tactgcataa atagttccat cttctctttg gccagatttc
     1021 acttcttgat catcgattac atcagtaata ttcgcccaaa tgactgtatt aaaaatacct
     1081 aaccccatat atccaacaga agtaagaact aagaatacat acatattact aggctttatc
     1141 aaaaataaaa gtaaatatac aatagcagag aagaacatcc ctactgacgc caattctttt
     1201 ttaccgtatt ttttactgaa aattaaactt acaggtgaaa caagtaccaa catcaaaata
     1261 ggattgataa agttcattaa aactattccc tgtgcattat tataataatc tggaaataca
     1321 taattgttca tactcattgt taaaagctga gcaagcaaca aaaaaatagc tgcagctatt
     1381 atagaaagca acgctctatt tttagctaat ccttttaaag atttcaacaa tgaaactttt
     1441 aactgcgatt catcactttt aacccgttct acagttaatt tataacatat tacgtaacaa
     1501 ataactgcac acactgaaaa tactcctgcc acaattgtaa aagttgatcc accacgtaca
     1561 atttgagctc cagaactatc tcttgtataa ataaaaattg gtgttaacac gccaatgaac
     1621 atacctgcta aggtagctcc tatactacga aatgttgata acgctgtcct ttcttctgca
     1681 acagaagtga tagctgatgc cattgaaccg taaggaatat taatagatgt ataaaaaata
     1741 cttccccata gtatatatgt tacatacata tatataactt taatactcat agaagctgat
     1801 gccattgatg tttgatacat taaaaaactt gctaaagcga ctggaccact catccgtaaa
     1861 atccacggtt taaatttgcc agttttagat ggttttgatc catccacaat acgccccatt
     1921 gttatgtctg taactgcatc aataaatctt gctactaaaa ataatgttcc tacggtagct
     1981 ccgcttatcc ccaatacttt tgtataaaaa atcattaaaa aagaactagc aaaaatgaaa
     2041 gtgaaatcat tcccaaaatc tccaaacata tatcctattt tgtctcttag accaaatttt
     2101 ctttccatat aatttgcgct ccttcctatt gttaagcgtt ttcattctgt tgaactgcca
     2161 acttacgtac tatactctga agtataaaga gttagtattt attttttaca ttttatagta
     2221 ttatttattt tttctcctaa taattcttta tctcataaaa cttatctata tatttactag
     2281 ctattcgagt tacttcttca aaatcacctt tttcaacagg agccaacaaa ttcccaccta
     2341 caccaactgc aacaacgcct gcttcaaacc actcttctaa gttatctaga cttactccgc
     2401 cagtaggcat tatatttaca tatggtaatg gagcttgata cgtttttaca acagatggac
     2461 caaaagcaga acctggaaat agtttaatga tttctactcc agcggtaagt gcctccttta
     2521 tctcagtaat tgtcatacaa cctggtaaat aaggaatttg atataaatta caaatctctg
     2581 ctgtttgtcg atcaaaagat ggacttacga tatattctgc tccagccata attgcaatac
     2641 gagcagtaaa cgcatctaaa actgtaccgg ctccaattat tacatctttt tgatcagcat
     2701 attttttagc aatttctttg attatttctt cagcattcgg aactgtaaaa gttagttcaa
     2761 tccctttaat tccacccgca gtaattgcat ttattgcttt aatggcctca tctttatttt
     2821 ttccacgtac aaccgcaatg actccagccg cttctaactt acttaaaatt tctacttttt
     2881 tcatatctat ctccttcttt tatggataca tactctagct agttgtacta acttacaata
     2941 aataaattta agcttttatt ttttgtatta ttttctactt tcgatttcaa aaaaattaaa
     3001 ataattatac gcattacgat aacaaatatt ctccactatc tgactaagat acatttcatc
     3061 atctggaatt cgacctgctt taacccactc gcttagtaat tgacataata ctcgacggaa
     3121 atactcatgg cgaggatagc ttagaaaact tcgagaatca gtcaacatac ctgtaaaatt
     3181 cgacaacaaa ctttgttgcg ccatcgtagt caactgttga cgcattcctt cagctgtatc
     3241 attgaaccac caagcacatc ccaattggat tttttgaatc ataccccctt ggaagctttg
     3301 cattgctgtt gctagtggaa gccaatcggt tggatttaat gaatataaaa ttgtttttgg
     3361 taagcaccca ctcttttcag cagtgtcgaa caatgctaca acattttgtg tcaaactagc
     3421 ttgatccccc atcgaatcac caccgacatc tactccaatt tgttccttta atatacttga
     3481 attatttctt aaagcattta aatgcatttg catcgtccaa ccatatcttg tatactcaga
     3541 catcaaatgt aattgaatac ctgtaacaaa ttgtgcaatt tctgataaat ggaaatccgt
     3601 ttttcctgct aaagctttta ttaacagatt gtcgagtatt ttttcatctg ctatttcata
     3661 aaaataagta ttcaaaccgt gatctgctaa tcgacagcca atttgatgaa aataatccac
     3721 tcgttggctc aatgcctgct tcaacccatt aaagtttttg attggtatac ccgctgcttg
     3781 actaagtttt aaaatatagt tcgaaaatcc tgatgatttg atactccaga ccttatctgg
     3841 acggaaagta ggtaatacct tgaaagaatt atcctgttta gaaagctcag tatgatatcg
     3901 caagtcatct gtaggatcat ccgttgtaca aatggctttc acatccatca tcttcagcaa
     3961 ttcttttggg cgataggaat ccgtttggat tttttcgttg gcacgtcgcc aaatttctgg
     4021 tgcattcttc tcagaaattg tcaaatcaat atcaaagtaa cgttgtaatt ccaaatgaga
     4081 ccattcaaaa ataggattac ctggcgcctt ctccactgtt tttacaaaag ctaaaaattt
     4141 ttcataatca ttacctgcac cactgatcaa ctcttcttct atcccattag ctcgcatcaa
     4201 tcgccattta taatgatctc cagctccttt atcatttaac catacctgag tcaaattctt
     4261 gtattgctta ttttctagca aacatgctgg gtctaaatga caatgataat cgatgattgg
     4321 ttggtgttct gcaaatttat gaaaaagtct tttagctatt tcattctcta ataaaaagtt
     4381 cttatctaaa aacatattta agcactcctt tccttccctt agtttttaga agagaaaatt
     4441 tttcttctaa atagactcca ttatataatt atttactcgc ccccttttca agcgcttccc
     4501 aaataccatt taaataaact gcacctagag ctcggtcata taacccataa ccaggtctac
     4561 cggtttctcc ccaaatcatc cgaccatgat ctggacgaat atagccatta aatccattat
     4621 cgtacattgt ttttaatatc ttatacatat ctagagaacc atattctgat ttatgcggcg
     4681 cttcataaaa atcgagtcca ttatcactta aatatttgat attacgaaca tgtgcaaaag
     4741 gaatccgatc ccgttgacaa aattcagata gaatttcata gacatcatta tctggtcgtt
     4801 ctgcaatact tccagtacat aacgtaatac cattagaagg agaatccact acattacaca
     4861 accattctaa atcgtcacga tttttaacaa tacgaggtaa tccgaaaata gaatatggtg
     4921 gatcatctgg atgaactgcc attttaatcc caacttcttc acatgtcggg ataattgctt
     4981 tgagaaaata tgcaaagttc tctcgcaatt tcgcttcatc aacttcttta taggcttcta
     5041 ataattgctt gatttgtgat aaccgatgag gttcccaacc cggcaattca aaattattag
     5101 tagaattttc tacttttcta ataatttcct ctggatcagt aggaatattt tttgaaatat
     5161 aggctaacgt agaagaccca tcatctaaat gataatccaa atctgatttt acccaatcaa
     5221 agactggcat aaaattataa cagataacct caatcccaaa ttctgccaaa ttgcgaatcg
     5281 tctgtttata attctcgatg tattgatctc gtgttggcaa accaattttg atatcatcat
     5341 gaacattaac actctcaata actttcaagg taaggccatt ggcttcgact tcatctttta
     5401 aagctttaat tcgttctctc ggccagacct ctccggctgg tatatccatt aatgttccaa
     5461 caattccttt cattgctggg atctgacgaa tttcttgtag tgagattttt tcttcatttg
     5521 ccccatacca tctaaaagtc atttccatag ttactttcct ccaacttctg ttatatattt
     5581 attgattgtt ttacgaactg cttgaggacc tactagcatt tcgcaaaaga ttttttcaat
     5641 tttctttcct atctcaactt gatataaatc taaaccaaat atttccttat tttctaagat
     5701 ttcctgtacc gcacaatgaa tctttgcagg atcttgttca cctaatttca atactgagaa
     5761 tttttcctgc aactctacca ataaaggatc aggacttggc acaaaatttt ttccttgatc
     5821 atcgactgcc aataaataac gtaaccaagc agcaatagcg ataggaataa atgttagatt
     5881 ttctgcattt ccgtcttttt cgacatactt tttaattgtt tcaccatagc gaatcgctac
     5941 tttttgagaa gtatctgttg caattcgttg cggtgtatct ggaatatagg gattaggcaa
     6001 acgtttattg attacttcat caataaattg ttttggatca ataacgcctg gactttcaac
     6061 tactggtaag ccttctacat aacctatccc tttaattaag ccaaccaaat catcatcttg
     6121 catttctgcc tgaattgatt tataccccaa caaacaacct gttattgcta atgccgtatg
     6181 gagcggattt aaacatgtcg taaccttcat gatatctgct ttatcaactg tttctctatc
     6241 tgtcataatc acaccagccg cttccagttt aggtcgacca tttggaaaac tatcttcaat
     6301 gactagataa tggacttttt cagtattggt aaaagcagcg atattggtat ttttcgcagt
     6361 atgaattata tctaagtctt cgaaacccgc cttcaataaa tccattttga cactttccga
     6421 aggatttggc gtaattctat caatcatact ccaaggaaaa gtcacttttt ctttatcctt
     6481 taaataagca ataaattttt cagaaacgta tccttttttt tgccaagctt ctgcaatcat
     6541 aaaaatgcta tcttgaaaac gttgaccatt ctgtgagaaa ttatcagtag aaaccatcgc
     6601 aatcggtaac tctccagcat taaacctgct atacaacaag gatgtcacaa tactcatcgt
     6661 atgttgagga ttggtaggtc cagattttat atctgcttcc actaccgaaa aaaattgtcc
     6721 tttagaatct tttaaactgt atcctttttc agtaatagta aacgttgtaa actgtaatgt
     6781 aggatcttca aaatatttaa ccactctttg atagtccgtt atattctttg gattgcaata
     6841 taaactatca gctgttactg ctaaaagtct ttttttgagt tcaccatctt cacccataac
     6901 aatctccaaa atatcattgt tgtagtcatg ataagctttt tctactactt cttcatcaaa
     6961 tgtctcacac acaactactc cggattctaa ttcattttga tctgctaagc attgagcaat
     7021 ttctgcatga aatcctcgat aaagatttcc tccaccaaaa tgaagccaca ctggatgttt
     7081 ctgaccttct tgtttgaccg cttcgacatt aaaatacggt agttgaactt gcattttgtt
     7141 caatccttcg atagaatctt gccagtcttt aatcaaaacc atatttaccc ctccatactg
     7201 atatgttagt ttccgttaca attgtagtat aaaatcgaat gtaatcgctg tcaataagaa
     7261 aaaactaaaa atattctttt ttctaccatg tcagaattat tgtgtctttt tttagtaaaa
     7321 gcacaccaat atatattttt tagaactaac ttaaattaaa gcttaatttc tctttgatct
     7381 tatttgagta ttttttgttt ttttaatagc tagtatgtta ctttgaaatt tgatattata
     7441 taacgagcat agaactaaaa tatcaaattc aaaaatgaaa ttttgagagg gattaaatat
     7501 gacaattaaa actagtctcc aaaatcaagc ttatcaatct attcgtcagc aaattatcta
     7561 cgctgactta gaacctggaa aaaaagtatc agaaaaaaaa ttggaagaaa cgctttctat
     7621 cggtcgtact ccaatacgtg aagcattgat tcaactccgt catcaaggac ttgttgatac
     7681 aattcctcaa agtggaaatt atatctcatt aatcgactta gatttagcaa aaaatgctcg
     7741 ttttgtcaga gaacatttag aacgacaaat tatgctagag tgttgtgcca agatgaataa
     7801 tcaaaagaaa caagttttag aaactataat tgcagaacaa gaaaaagctg ttagtcaaaa
     7861 gaatgctcgt agtttttttc ataatgataa tttatttcat aaagcttgtt ttgaaattgc
     7921 agaacgggaa gaagtatggc aatggttgga agataataat acgcacttgg aacgatttcg
     7981 ttggttacga gtaaaaacgg aaggattaaa atgggaaaaa attatggaac aacatcatca
     8041 actatttaaa gccttgacca tgcaagaccc tgaagaagct aacttcttaa catccttgca
     8101 tcttcattta atgcttgatg aacaaaatgt tgtattgact actcacccaa aatat
//
LOCUS       DACGDM010000108         8137 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.114, whole genome shotgun sequence.
ACCESSION   DACGDM010000108 DACGDM010000000
VERSION     DACGDM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.114"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            94..1248
                     /locus_tag="IXR05_002479"
     CDS             94..1248
                     /locus_tag="IXR05_002479"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAQ4260947.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            complement(1270..2022)
                     /locus_tag="IXR05_002480"
     CDS             complement(1270..2022)
                     /locus_tag="IXR05_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4260948.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(2386..5052)
                     /locus_tag="IXR05_002481"
     CDS             complement(2386..5052)
                     /locus_tag="IXR05_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4260949.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5393..6844
                     /gene="cls"
                     /locus_tag="IXR05_002482"
     CDS             5393..6844
                     /gene="cls"
                     /locus_tag="IXR05_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4260950.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            complement(7173..7988)
                     /gene="thiD"
                     /locus_tag="IXR05_002483"
     CDS             complement(7173..7988)
                     /gene="thiD"
                     /locus_tag="IXR05_002483"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAQ4260951.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         2363 a         1693 c         1451 g         2630 t
ORIGIN      
        1 aatccttaaa tattctcttt tttatatttc ttttaatctt tttatgatac cttagtaaag
       61 taagtttttt atcataagta aagaggtgtt gaaatgaaaa tagggattga tcgtctttcc
      121 ttttttattc ctaatttata tttagatatg acagagttgg cagaaagccg tggggatgat
      181 cctgcaaaat accatatagg gattggtcaa gaccaaatgg cagtcaatcg tgcaaatgaa
      241 gacatcatta cactaggagc aaatgctgcc agcaaaatcg taacagaaaa agaccgtgag
      301 ctaatcgaca tggtcatcgt cggaacagaa tccgggattg atcattcaaa agcgagtgcg
      361 gtaattatcc accatttact gaaaatccaa tcttttgctc gttcttttga agtaaaagag
      421 gcttgctacg gtggcaccgc agctttgcac atggcgaaag aatatgtcaa aaatcatcca
      481 gaacgaaaag tactagtcat agcaagtgat attgctcgtt acggcttggc aagcggtggt
      541 gaagtgacgc aaggtgtcgg tgctgttgcg atgatgatca ctcaaaaccc gcgtatttta
      601 tcgattgaag acgacagcgt atttctgaca gaagatatct atgatttctg gcgtccagat
      661 tatagcgaat ttcctgttgt tgatggtcct ttatctaatt ctacgtatat cgaatcattc
      721 caaaaagttt ggaatcgaca taaagaattg tcgggtcgag gactcgaaga ttatcaggcg
      781 attgctttcc atattccgta tactaagatg ggaaaaaagg cattgcaaag cgtattagac
      841 caaacagacg aagaaaatca ggaacgtctt atggctcgct atgaagaaag catccgttac
      901 agccgacgaa tcggtaatct ttacactggt tcattatacc tggggctaac ttctctactg
      961 gaaaattcga aatcactaca gccaggagat cgcatcggtc tattcagcta cggttctggt
     1021 gcagtaagtg aattttttac aggttatctg gaagaaaact atcaagaata tctcttcgca
     1081 caatctcatc aagagatgct agattctcga acacggatca ctgttgacga atatgaaacg
     1141 attttcagtg agacgcttcc tgaacacgga gaatgtgcag aatatacttc agatgtacct
     1201 ttttcgatta caaagatcga aaatgatatt cgttactaca aaatataata aaatcataaa
     1261 aagaaccctt cacgagtcgt gaaaggttct ttttttatct gcggaccaaa ggagcagtct
     1321 ataggtcagc ttagtcgtac taaggatttc tcgtttttca ctgaatagtt tgcgaatgta
     1381 cctggtcaca acaggatctt ttgcgtacgc gtcatagtat agcttcatca attcttcagt
     1441 aattgattcc tgtgtaaaat aagtaaaatc ttttttcttc actttgaatc cttcatcaat
     1501 taagtatgtt tcaaattgat ccattacaac tggcgatgta ttaggatctt cttctatcat
     1561 tcctagttgc ttttcgatag gataaaaaac atcatcgatt gattccacta ctctgattat
     1621 cacgcaccat ttgcttgact ttttcatcaa tttttctaat tgaataagat gtaccaatgc
     1681 tggatttgct gctgtaaaaa ccatttcata tgtctcattt gattggataa attcttctaa
     1741 cgactgtttg ataaaggaaa catttggcaa ctcatttttt tctgcttctt tttttgcatt
     1801 ttctagcatt cctgaagaaa aatcgatcaa atcatagcga ttaatttctt ttgctaagga
     1861 aagaaatctg ccagatcctc cagcaacgtc tgctgctgtt tcagcaggca ggactttctc
     1921 cgttttcaga taatttttta catcttcagc aatagttact tgcgattctt gctggatttc
     1981 ataatattct tcagcaaatt catcccattc tttttcattc atttgatttc ctctaatttt
     2041 ttgttatatg ttttcacttt tcggaataaa tcattctcct cttttatcta ttctatctct
     2101 tttgatgaat aataaaatga ttggctttcc gtctatcata aataaaaaaa gggactgtga
     2161 ccaaagtcgt gtcaaagtcc ctctttccga ataaacagtg tccaatcaga tgaccctcag
     2221 tattagctca aaatgctgat tttacaactt cttccttaaa cggtgttctc ctgccaactc
     2281 ttcggtcaca agtcacaata ttcaacaaac atgagaagct gtttgttgaa attgcacctt
     2341 gtgactcaga attaaacggc aggctcacaa cctcgttgat tcgttttatt tatttccttg
     2401 tactcgtaca atgatcaatt tagtgatttc catcaaaaca attgtcacaa gtgcgattcc
     2461 catacatgta aagacttctg tcaatccaaa tgctgatggg atagagaaga cttctttcag
     2521 tcctgggatc attgttaagc agtaaagcgc gctacataca actacagcta gtaagacact
     2581 tctgttagag aagaaccctg cttggatagc tgtttgtgtg tttgaacgtg ctgggaatgt
     2641 ttgcaatgtc cgacaccaaa tcaatgttga aaatgacatg gctacaccga attcaggtga
     2701 atgctgcatg ccaagccatt gagcaaagat aacagcaatc ccaatcagca caccacgata
     2761 cgttacagaa atcaatgttt tgtccgtaaa gattcctgaa tttggatctc ttggcgggcg
     2821 gttcatcgta gcaggttcag ctttttctgt acctaatgca attgctggca gtgaatcatt
     2881 gactaaattg atgaacaaca gttgtaatgc tgtaaatgga ttggaccagt cagcaactaa
     2941 ggcaaagatg atcgcaatga tcgcacctaa atttcctgca aatagataag aaatagcttt
     3001 cttgatatta tcaaacacat tacgtcctac ttctactgcg ctgacaatag aagcaaagtt
     3061 atcatccgtc aataccatcg ctgctgcatc ttttgccaca tctgtacccg ttcccatagc
     3121 aattccgatg tctgcttgtt tcaatgctgg tgcgtcattt acaccatcac ctgtcatagc
     3181 tgagatatga cctttatttt gccaagcacg aacgatacga attttattct caggtgaaac
     3241 acgtgcataa acagtgactt tttctaaaac ttcgtttagt tgatcttctg tcaattcatc
     3301 tagttccgtc ccggtcaaag ccaggtttcc ttcttcaaaa atcccgattt gttttgcgat
     3361 agcaacagct gttgttttgt ggtcaccagt aatcatgatt gttttgattc ctgcacttct
     3421 tgcttctgtt accgcctgag tcacttcagc acgtggagga tcgatcatag caagcaaacc
     3481 aacaaggatc aaatcgtctt catcttcaaa tgataaatca aaattatcaa gtggacggta
     3541 agcaaaagct agtacacgta atgcgcgtgt tgaaaaagct tcattttgct cttggaattt
     3601 tttcatcaat tcatccgtca tcggaacgac ttcaccattt agcaatactt ttttactgcg
     3661 ttggaagacg atatctggtc cgcctttaac aaacaagtaa tttttgttat caattgtgtg
     3721 tccagtagac attaattttc gatctgagtc aaaaggaagt tctgcttgtc ttgggtagtt
     3781 gtttcggatt tcctgataag gctggtttaa tttttcacta aagtcgataa acgctacttc
     3841 cgtagggtcg cccaatttag taccgtcttc actgatcgat gcatcattcg ctaaaacact
     3901 gatttcgatc aagcgacgtt cgtcagctgt ccattttgaa gggtcatttg tgaaatcccc
     3961 agtatcgcca ttacctaaaa agtagtcaac aactgtcatt ttgttttgtg tcaatgtacc
     4021 agtcttatct gtacagatga tacttgtcga accaagtgtt tcaactgctg gaagcttccg
     4081 aataatggca tgacgttttg ccattttatt cgttcccaaa gataacacga ttgttacgat
     4141 agactgtaat gcttctggaa tagcagctac ggctacggct acggcaaaca tcactgcgct
     4201 gacgatatct gcagtcatat ctcctgtacc ttctccaaga taaatacgaa acagttggat
     4261 acctaaaatc aataaagaca atgccaaaat agccaaactt agttttttac tgaatttatc
     4321 cagacctcgt tgtaacggag tgacttgctc agttgttgat tccaaaaggc cagcaacttg
     4381 tccgatctcc gtattattcc cagttgaagt cactaagaat ttaccgcgtc cgtaagttac
     4441 gatcgttcca ctgaatacca tatttgtacg atctccgatt ggtaccgtac ttgtgatatc
     4501 cgttacttct ttttctgcag aagtcgactc tcctgtcagc ataccttcat ctacttttaa
     4561 tgatcccgca tctagtaaac gtccatcagc aggtacataa tcgcctgcgt ctaacaacac
     4621 gatatctcct accacaagtt cgtttgccgg aatcgttttt tccttaccat cacgaatcac
     4681 tcgagcatcg ggcgctgaaa ggtttttcaa cgcttctaaa gaaccttctg ctttttttgt
     4741 ttggacaaca ctgattatag aattcaacat caatactgca aaaataacta agaattcgat
     4801 gtagtcaccc atgaccatct gaatcagtgc gacaatcagc aatacgataa ccattgcatc
     4861 tttgaaagtt tctaagaaca atttccaagt tggcttcttc ggcttttctt ttagctggtt
     4921 caagccatct ctttctaatt tttccttcgc ttgcgtggtg ctcaatccat cggttgagct
     4981 ctgcgtttgc tgcatcaacg agtcgatcgt ttctttatag accgcttgtt gtgcttgttc
     5041 cttgttttcc aaatttcatc ccccattttt tgatcttggc cctagtcctg tctgaaaaaa
     5101 aagagaccta agacaaatac gcatttgtct taggtctcac catttcatac aataccagaa
     5161 aaccatttgg ttaacttact gttgatatta tcgcaacaaa cgttgccggt tactccccta
     5221 aggagatatt caactgtact aatatcctac cttattaacc tacaaaaagc aactacttta
     5281 gcccgattta cctacatttt catgaaagga gtgaaaagta tattcacctt ggtaggcttc
     5341 tttcttctat catgctatac taatgttatt gtatgtaagg aggaacattt ttgtggtatc
     5401 tagtattata accgcccttt atctattaaa tgcacttatt gctttggtgg ctattttgat
     5461 caaaccccga gatgtagcag ccatttgggc atggctctta gtattgtttg cccttcctgg
     5521 ggtgggcttt gtattatatt tatttttcgg acgtggatta acggataaga aaaaattcta
     5581 tctccgacaa agtgacttga aagaattaga aaactttcag tcttttagag gagataccat
     5641 tgaacattac gatcctgaca tgggcgataa agacaaacag caatttgttg acttcttctc
     5701 ttcattaaat cgtatgccgc tgacaagaat gaattctgtc actcttctca cagacggaca
     5761 agagaaattg gattcactgc ttcaagatct aaaaaaagcc aaacattcga tccatatcga
     5821 atattacgca tttgtgacag ataatatcgg ccagcaagtc ttacatgttt tagaagaaaa
     5881 agccgcagaa ggcgtggaag ttcgaatatt atatgatgca tttggctctc atggcacaaa
     5941 agcaaaagat ttcaatcgtc taatcaaaaa tggtggacat gtccatacat ttgttacctc
     6001 acaaagggca ttacttcgtt tccgattgaa ttaccatgat caccgaaaaa tcgttgtgat
     6061 cgatggaaag attagttata ccggtggttt caatattgcc aatcaatatg taaatacaac
     6121 aaaaaaattc ggctattggc gcgatacgca tatacggatt ttcggtgccg cttcttcttt
     6181 gctccagctt cgcttcttaa cagactggaa cgtctcggta cctgaagaaa aaaaggtcgg
     6241 ctatcatttg aattatttct ttaaaaaagc agatcgagat gaatctaagc ttgctgatac
     6301 atccatccag cttgtttcaa gcggaccgaa taacgaaagg gaacaaatca agctttcatt
     6361 tatcaaattg attacttctg ctaaaaaacg tgtttggata cagacacctt accttgttcc
     6421 tgatgaaagt gtcattgctg ctttaaaaat cgcaactgcc tctggtgtag atgtgaaaat
     6481 catgattccc aacaaaccgg atcatccttt tatttatcga gcaacacaat attatgctcg
     6541 gcagctgatc aaggaaaatg tacaaatcct tgtctatgag aacggcttcc tccatgcaaa
     6601 aacattgata atggatgatg aaatctgcat ggtaggttca gcaaatcaag atattcgtag
     6661 ctaccgattg aattttgaaa caagtgctgt catttacgat cctgagtttt tagaagaact
     6721 tgctactcag ttcaaagaag atgagacaca ttgttcatcc atgacaactg aaacagtcaa
     6781 ggaaatgtct aactggctat tattcaagca acaaatttct cgattatttt ctccaatcct
     6841 ataatttttt tattcaagta gagaaaaata tactaagatt aaagggactg tgacaaaaat
     6901 cttgtcacag tcccttcttc cgaacaaacg gtgttctcct gccaactcct cggtcacaag
     6961 tcacaatatt caacaaacat gagaagctgt tttttgaact tgttccttgt gactcggagc
     7021 tggacggcag gctcacgacc tctttcttaa acggtgttca aaagcttgca tctgcggtaa
     7081 taagtccaac caagttaaaa acataagaag ctgtttttac ttggctgttc ttattacttg
     7141 atgcagggca actttttcac aacttctttc ttttactcta attcaccagc tgcccaatga
     7201 ttgatggggc catatttgtg ccctacattt atttcttcac gaattgcacg gtttacatag
     7261 tcttttgcca atcggatcgc ttgttcaact gtttttcctt tcgctaactc agctgcaata
     7321 catgcagata gcgaatcgcc agttccgttg atccggtcgg taggataaaa tggtgcattt
     7381 aaccaaaatg attttcctga ttcgaacaat acgtagtcat tgactgtttc ttgctgcgca
     7441 tttttagcat gatgtccttt gatcataacg ttttttgcac ccatatcttg cagttctttt
     7501 gctgcttgca caaaatcttc ttcagctgct aatgtccgtc cagtcagctt ttctgcttca
     7561 taaaaattag gtgtcagtac ttcggccaaa gggacaagct tttctttcaa gctttgcaaa
     7621 gcagattctt ctagtaaaag atttccatgt ttcgttacga ttacgggatc cacgactaat
     7681 ggtccaaaat catatttttg gtaatttttt acaactgtct caatcaactt tgaatctgct
     7741 agcatacctg ttttagctgc acgtatttga aagtccttcg caatcagttc aaattctttg
     7801 tcgataaaat ctgttggcaa tgtcacactt gctccgattc cgtaagaatt acctgcaaca
     7861 catgcggtca tgacagaaac accgtaaaca tttcttgtaa agaatgtatg catatctgct
     7921 tgcatccctg cgcttccatc gctatctgat cctgcgatcg tcattgcttg tacatactga
     7981 tcttccatca aatcgattcc tccattttta taaaaagatt tttcataata ctgttactgt
     8041 ttctatcata tgtttttcaa agtatccctc agtaaatata ccactacctt ttcttggtaa
     8101 tcaaatttat ttgaaaaaac atttgcaata aatcaga
//
LOCUS       DACGDM010000109         7907 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.115, whole genome shotgun sequence.
ACCESSION   DACGDM010000109 DACGDM010000000
VERSION     DACGDM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.115"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            86..787
                     /locus_tag="IXR05_002484"
     CDS             86..787
                     /locus_tag="IXR05_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4260952.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1396..2412)
                     /gene="tsaD"
                     /locus_tag="IXR05_002485"
     CDS             complement(1396..2412)
                     /gene="tsaD"
                     /locus_tag="IXR05_002485"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAQ4260953.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2409..2873)
                     /gene="rimI"
                     /locus_tag="IXR05_002486"
     CDS             complement(2409..2873)
                     /gene="rimI"
                     /locus_tag="IXR05_002486"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4260954.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2880..3422)
                     /gene="rimI"
                     /locus_tag="IXR05_002487"
     CDS             complement(2880..3422)
                     /gene="rimI"
                     /locus_tag="IXR05_002487"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4260955.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3406..4230)
                     /gene="tsaB"
                     /locus_tag="IXR05_002488"
     CDS             complement(3406..4230)
                     /gene="tsaB"
                     /locus_tag="IXR05_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAQ4260956.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(4319..5299)
                     /locus_tag="IXR05_002489"
     CDS             complement(4319..5299)
                     /locus_tag="IXR05_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4260957.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5323..6807)
                     /gene="galT"
                     /locus_tag="IXR05_002490"
     CDS             complement(5323..6807)
                     /gene="galT"
                     /locus_tag="IXR05_002490"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAQ4260958.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6819..7808)
                     /gene="galE"
                     /locus_tag="IXR05_002491"
     CDS             complement(6819..7808)
                     /gene="galE"
                     /locus_tag="IXR05_002491"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAQ4260959.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2221 a         1699 c         1400 g         2587 t
ORIGIN      
        1 ttctaatgtt ggtatgttaa aactttacaa attctttaaa aaaagtgaca ataaatatag
       61 tgaacaataa ggagaggact ttttaatgcg tgttaataaa atcgattttc acttttcaaa
      121 actcagatat caacctgatt ttgaacattt ctcggatgaa gagttccaac agatcaagga
      181 acatactgtt cttcgttctt ataaaaaagg acagatcctt ttcgacgatg gtgatcccag
      241 acaacggttg tatatcttga ccaaaggact cgttcgttta gaacgttatg atgaaagtgc
      301 aacttattac tactatgact atgtgaatac aaataacctt tttcctatgt caggaatgtt
      361 tggagaagag acctacactt atacagctca agcgatgact gatattgaaa cattctacct
      421 tcctgtttcc tactatgaaa aattagcacg aaaaaatccc gaacagttga tctatatgat
      481 acaaaaaatt tctaaagtag ttgaaataca tgaattgcgt atccaaatcg gattgacctc
      541 tagcgccttt gaccgggtaa aacaaaattt attcattttg aaagaagaat tgggcgtacc
      601 aacaaaagat ggtcatatca ccattcctta tccgatcacc ttaaaagaat tagcagtgaa
      661 tagcggcacg acacgtgaaa ctgctggaca agtaatcaaa caactacgtg attccgggct
      721 gttagattat gacaaaaagc gttttacttt ctgtaagaca gctactactc cagctatgag
      781 agaataacgc gaacaaaaat aagcagtgac cctgataaat atcagggtca ctgcttattt
      841 tcctccctaa aacttctgaa agatccggca gttttagatc actggacaag actcaaagat
      901 tttctatgtg tgtttcagtt atgtaatatt cactgtttgc aaaaaatact gttagattaa
      961 ctagatgaag cgtcttgtcc tcatccgatc tagattattc gatattcctc gacaataaac
     1021 gattactcag tgagggcaat cagaggaacg gataatgata aataagctgt aaaaaatagc
     1081 aaaataacaa taatgattaa aagtatgtaa aaaatagggc tttgacaaaa acgtgtcaca
     1141 gccctatttc gattaaacgg tgtgtacctg tcaactcttc ggtcacaagt cataatgttc
     1201 ataaacatga ggagctgttt tttgaaattg ttccttgtga atcagagtta aacgacaggc
     1261 ttacgaactc ttgattaaac ggcgttcaaa agcttgcata cgcggtaata agaacagcca
     1321 ggtcaaaaac atgagaagcc gtttttcctg ggctgttctt attacttgat gcagggcagc
     1381 tttttcacaa cctctttatt cagataaaac caagcttgga tcagcattca actgatagct
     1441 agcaaaattt cttttttgca tttccacatg tgctgctgct ccaatcattg cagcattatc
     1501 tccacaaagt cgaagagggg gaatcactag ttctacctca gggagtttag ctgccaaagc
     1561 atcctgcaat ccttcacgca acccttgatt ggccgctaca cctccagcta taatcagttg
     1621 cttgactgga taattttgac aagctcgaag tgttttagta atcaatacat cgatcacact
     1681 tgcttgaaag ctagctgcta aatcattttt gtctagatct tctccacgct gttgtgcatt
     1741 atgcaccaaa ttgataaatg cactttttaa tccgctaaaa ctgaaatcat aattatcttc
     1801 atggatcatc gctcgcggaa aatggtaatt atcttttccc tgatgagcta gctgatcgat
     1861 ttcttttccg cttgggtaag aaagacctaa tactcttcca actttgtcat aagcttctcc
     1921 tgctgcgtca tctcttgtct ccccaatgat ttcatatgat ccatcttctt gcatatagac
     1981 taattctgta tgtcctccgc taacaagaag tgccatcaat ggaaactgga atggtttaac
     2041 cagacgggct gcatagatat gccctgccat atggtttaca ggaataagcg gcaattggtg
     2101 tgcccaagca aaagccttag ctgcagaaat accaatcagc aacgagccga caagtcctgg
     2161 tccataagtg acagcgactg ccgataaatc ttctgccgac acaccagctt ctaccagtgc
     2221 atcttccaag cataaggtga tttgttctac gtgatggcgg ctagctactt caggtactac
     2281 gccaccaaaa cgtttatgac tgtttatttg agaagcaacg atgttagata agatctctgt
     2341 tccatttcta acgaccgcta cactcgtttc atcacaactt gattcaatcg ccagaatcaa
     2401 ttcttcattc atttcatcgt ctccgttttt aactttctgc tcataatgat cgcatcttcc
     2461 gtcggattgc gataatatga tttccgttta cctaatatac gaaacttttc tgattcataa
     2521 agttttcttg ctgcttcatt agatagacgt acttctaaaa aaacatgcag cgaatctttt
     2581 atttgttccg taatcagtaa ttgtaacaaa tgccgtgcat gcccttttcc ttgttctgaa
     2641 actgcaacag caatatttgt gatctcgact tcatctatta ctttcgagta tccaataaag
     2701 ccacagatct ggttatcttc agctaaaagc agataatcag agtgaggctg ttggatgtct
     2761 gccaaaaact gcattttcgt ccaaggtgaa ccatgtggat aagcattttc gctaatcatc
     2821 catacgcatt ctgccaagta cgcttcatca aaatcttttt ttctgcaaat caactaatct
     2881 cactcatttt ctaaaagttt tatcatatcc aacgcatctt cttttgtttc agtgtaatat
     2941 ctttttttga tcgttgttgc ttgaaacccc aatttccgat aaagtctttg tgcatcttga
     3001 ttactcatac gcacttctaa tgacatcgtc tcacagcgat tcattatagc aaagttctcg
     3061 atttcgtcaa taagcagcga accgattcgt ttacgctgat atgccggtcg aacggcaata
     3121 ttcgtgatat ggcaatctaa accgaacgct cttgaaccga taaaaccaat cattcttcca
     3181 ttatcaaaga tacctagata tagatgagga agcggtgact tcaattctga tataaaggca
     3241 ctttttgtcc atggcaattc gccattatag acttctcgtt cgacatccag cagctctttg
     3301 atatcttctg tagtcaattc tcttagtacg taacgacgat cgatttgttc gactgttttt
     3361 tctgtataaa tcattttatc ttgaaaaaag cttctggcat acgctctaaa ttttttcaac
     3421 ataactttcg tctccaggtg tgtgcgtctc caaccatttt tcttctgctt ctactcgttt
     3481 taaatagcga ggaagaaaag cttgtttctc tgcaactggt tcaactaaag cacctaattg
     3541 agccacagtt acaccacttg gaatatccca tgctggaact gtattaatca tcgcactagg
     3601 caatatttcc tttatttcag agaagaattt gtgacaatca ctcccgacga aataaatagc
     3661 ttcattcagc ttttgtagtt gtgtgaacaa atcagaagca gaaatatgta catcttcaag
     3721 tacagtttct aatctatttt ctttccagcg gtatgcccca gcgtatacat tttttcttcg
     3781 agcatcaaac atgggcacaa taatattatc cacaccgatg caattagccg cgatggtttt
     3841 cagactagat actcctacta gctctttatc taatgtataa gcaatcgttt ttgctgtcgt
     3901 tacacctata cgaagccctg tataagaacc gggaccatca gaaaccgcga ttcggtcaat
     3961 gtcttttgga cttatttgaa gatctgcaaa caattggtcg attgcaggca tcagtgttac
     4021 actgtggttg cgtttgatat ttgtttgtat ttgtccaaga atttgttcgt cttctaccac
     4081 accgatcgcc aaagtttggt ttgcagtatc tattcctaat gtaatcatat atttgatcct
     4141 ttctgctatg acattctcgc cttccattgt agcatacttt tttattctga ggatgaaaat
     4201 accaaaggca aaactagtac aataatacat gattatctgc tggcgggcaa attttgcccc
     4261 ttcctgaaac acaaaaaagc tgcggtatca ctccattttc ccacagcttt tccatctttt
     4321 atttcgttga ttctcgaata atcaactctg tttccacaat aatctttctt gaaaccggtg
     4381 ctttggaatt acttaattga agaatcgtct ccactgctag ctctcccatc cattcggtat
     4441 aaacttttac agtagaaagc gagggcgtta catatttcgc tacactgaca tcattgaagc
     4501 ccatcacaga aatatcttct ggtaccacta aacctttttc ttgaatcgct ttcagtgcgc
     4561 caatcgctaa tgcatcatta gctgcaaaaa gcgcatcagg aacatgcgga ttcgttttta
     4621 aatattgctt cactgcttga tatcctgact cgacagaaaa atctgcttcg ataattggac
     4681 cttcgtcgta gcctttttct gccaaaactt gttgaaatgc cataattctg ggatctttta
     4741 gccgctgatg gtttttcttc gtatattctg ttccagcaag catagcgata tgttgcgctt
     4801 tatgggagac aaagtgttca atgacttttt gaacacttga cttaaagtcg acaactagag
     4861 agtcgattcc ttgagaagtg ccgtcagaat ctaccaaaag caaggcattt tgggatcctt
     4921 tcatttctaa taactgagct tcgtcgaatt ttcctagtgc gatcgttcca tctgccggaa
     4981 gatcactaat ggaatcccac gtttctttca ataaagtaac gtttgcttct tctgcctttt
     5041 tttcgattcc taggcgaata gataaataat aaagatcttc aagctcttcc gtatcgtcgt
     5101 accactggat caggcgaagc gtttgcttag tatttgctgc atttttacga tgtttcgtat
     5161 aatttaagcg ttctgctgct tcaaaaattt tttgctttgt ggctaagcca acggaaagat
     5221 caggatcata gttgagaact cttgaaacag tagcaggaga aactcctgcc aactgcgcaa
     5281 tgtctttaat tgttgccatt tgtctctcct ccttttttac gtttataaaa tcgcagtaaa
     5341 tcgttcaaac gctgcctgtc ctttttcatc tcgcttgaat actccagcgt cttccagtac
     5401 acgtgcaaaa acctgaccta cagatttttg tacgacatcg gtgaccgtat ctttcgtcaa
     5461 atcaggatgt tcttttttta attgttctgc ccacggacga tgatattcag ccatctggtt
     5521 ttcttctcct aataagaaat gctctacttc tactagttct ggtttcaaac gaggtggtaa
     5581 aacagcaagc cccattactt cgatcaaccc aatgttctcc tttttgatat gttggacatc
     5641 tttatgtgga tgaaaaatcc catcaggatg ttcttctgaa acattgttgt ctcgaaggac
     5701 aaggtccaac tcaaagtaat tgtcccttct tcgtgcaatt ggcgtaatcg tatggtgtgg
     5761 tgtaccatct gctgaaaaag ctctgataga tactgtttca tccgaatatg ctttccattt
     5821 ttccaatact gagttagctg cttcaataag caagtttttc tctgttgatt gcaaacggat
     5881 cacagacatc ggccatttca cgactcctgc gatgacttgc ggataatctt ctagtttgat
     5941 aagtttttct atcggtgctt ttgccatagg aaattcatga cgtcctgcct gataatgatc
     6001 atgagaaaga atcgatcctc caacaattgg taagtcagca ttcgaaccaa caaagtaatg
     6061 aggcaagact tcagtaatcc gaagcagtct agcaaatgtt tcctttgtga ttttcatcgg
     6121 gcggtgttgt tctgataaaa tgatcgaatg ttcattgtaa taagcataag gggaatattg
     6181 gaatccccag ctttcaccgt ctagattcat tcgaataatc cggtgattgg tgcgggctgg
     6241 atagttcaag cgacctctat atccttcgtt ttccatgcaa agcatgcagg taggatagtc
     6301 tacttttacc gcctcgcgtt ctgctgcgat ttgttttgga tctttttctg gcttagataa
     6361 attgattgtg atttccagtt caccatactc cgactctgcc ggaaatttga tgttttttgc
     6421 gatggctctt gttttgatgt agtcattttt cttacttaaa ttaaagaaat actcagttgc
     6481 ttcctctggg cttttcgaat agtgctgtgc aaagaatgca ttgacgactg aaggtggcgg
     6541 tgtgagaaaa tccattaatt gcgcttcaaa aatctcttgt tctgctggca attctgaaag
     6601 aacaccattt tctcttgcct tagcgacaag ctgatccaat aagtctacag attcttcctt
     6661 aactggtctt acttcaatgc tttctagagc atcttctcct accatcccta aaagacgatt
     6721 ctgtaaatat aagcggtcca tttccatcca tccgccagct tcgatcgcaa gtgtggcaaa
     6781 atcacaaatc gtttgactga ttgacatatc tcattcccct attcttcata accatttgga
     6841 tggctgacat gccaatccca tgctgttttg ataatcgctt tgatatctgt gtattcaggt
     6901 ttccagccca gaatctctct cgctttttca cttgaagcga ctaatcggct aggatctcca
     6961 gctcttcttg gtgctatttc tgctggaatt tcttttcctg tcacttctct agctgcttct
     7021 agcatttcct tgactgagta tcctttgctg ctgcctaaat tgaagaagtt gctttcattt
     7081 ccttctttca agtattccaa agctaaaata tgtgcagcaa tcaaatcttc tacttgaaca
     7141 taatctctga tacatgttcc atctggtgta tcataatcgt ctccataaac agccaaggct
     7201 tttctttgac caagagctac ttgtaaaatg attgggacaa gatgcgtttc tggtgtatga
     7261 tcttctccga tagatgcatc tgcttttgct ccggctacat tgaagtagcg caaagcgaca
     7321 tagcgcatgc catatgcttg gtcacaccac ttcatcattt tttccatcat caatttactt
     7381 tcaccatacg gatttttagg attagctggt gtatcttctg tgattggaga ctctttcggc
     7441 tctccataag ttgctgcagt agaagagaat acgattttat tcacgttgaa ctcgtgcatg
     7501 acttcaagta agatttgcat accgtatacg ttgttgttga aatacatcaa tggtttttcg
     7561 acagattctc ctactaaaga gcttgcagca aaatggatta ctccttcaat cggttccttt
     7621 tcaaatacgg aacgtagaaa ttctttatcc cggatgtctc cttcataaaa atgagcatct
     7681 ggatgtactg cttgtttgtg acctgtgagc aaattatcta ccacagctac ttgatacccc
     7741 ttttgaacta gctggtctac agcgtgcgaa ccgatataac cggctccgcc tagtactaaa
     7801 attgtcataa aaaacactcc tttgattagt aaaattgtgt ttgttgattc tatataattt
     7861 aaaaaacgaa gtttactttt atggtgaaaa caaacaaagt aaaattt
//
LOCUS       DACGDM010000110         7893 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.116, whole genome shotgun sequence.
ACCESSION   DACGDM010000110 DACGDM010000000
VERSION     DACGDM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.116"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            250..2016
                     /locus_tag="IXR05_002492"
     CDS             250..2016
                     /locus_tag="IXR05_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAQ4260960.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2118..3377
                     /locus_tag="IXR05_002493"
     CDS             2118..3377
                     /locus_tag="IXR05_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4260961.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3524..4825
                     /locus_tag="IXR05_002494"
     CDS             3524..4825
                     /locus_tag="IXR05_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4260962.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4828..5679
                     /locus_tag="IXR05_002495"
     CDS             4828..5679
                     /locus_tag="IXR05_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4260963.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5692..6507
                     /locus_tag="IXR05_002496"
     CDS             5692..6507
                     /locus_tag="IXR05_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAQ4260964.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6658..7824
                     /locus_tag="IXR05_002497"
     CDS             6658..7824
                     /locus_tag="IXR05_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4260965.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT         2585 a         1362 c         1580 g         2366 t
ORIGIN      
        1 aaaaactgtt aaaaaacttt tactttagaa aattggagaa attgatcgct taagataaat
       61 tcaggacact aaatagtaca ggaagtagac taaaactttt aaaagtttta agtctatcta
      121 tttggcaagt ttaaaaaata aaaattcggt atcaaaaaac tgttaccgat aacatttttg
      181 aaagcgttgt cttttgcttc tctatcactt atagtgatga cgtcatatta aaacacaagg
      241 aggaaatcaa tggatacagc tgcaatttat catcgaccgg aaagtgaata tgcatttcta
      301 tatacgaata caagatttcg tattcggctt cgtactagga aaaatgatat caaaaaagta
      361 tatgtgctat gtggagatcc atataccata acaactgaaa aatggtatca aaaacaacga
      421 ccaatgaaaa aatgtctaag taccaatgtt catgattatt gggaaattga agtgacgagc
      481 gaaacaagtc gcttacagta tgcgttccat gttgttgggg aagataacac ggactgtttt
      541 tacggtgatc aaggaatttt tccttatcga gaaaatgtga ttactgaacc aaatttttat
      601 tttcgaatac cttattttca tcaaatcgat cgattcacta ttccagaatg ggtaaaagaa
      661 acagtatggt atcaaatttt tcccgaaaga tttgcaaacg gggacaaagc aaatgacccc
      721 gaacacactt taccttgggg aagtaaagat ccagaccgag aagacttttt cgggggagat
      781 ttgcaaggtg tgatggatca tttggattac ttgacggacc ttggcatcaa tggcatctat
      841 ttttgtccca tatttaaagc cacatccaat cataaatacg atacgattga ttattatgag
      901 gtggatcccg cttttggcga taaaaaactt ttaaaaaact tgattgatga agcacataaa
      961 agagggatac gtatcatgtt cgatgctgta ttcaatcata tgggtgtcca ttcaccacag
     1021 tggcaagacg ttctcaaaaa cggagaaaaa tcgatctata aagactggtt ccacatccgt
     1081 tttttcccag tagattctta tcagatgact gacttaccag aaactgctga aaatatccca
     1141 tatgatactt ttgcttttac tccattcatg ccgaaactaa atacagcaaa tccagaagtg
     1201 caaaaatatt tgctggatat cgcaacttat tggataaaag aattcgatat tgatggatgg
     1261 cgtcttgatg ttgctaatga agtcgatcat catttttgga aaaaattcag agaagcagtt
     1321 acagaaatca aaccagacat ctatatcctt ggagagattt ggcattcctc tcaagcttgg
     1381 ctgcaagggg atgaattcca tgcagtgatg aattatgcat ttacagattc gattaaagat
     1441 tattttgcaa aaaagaaaat cacagcttca caaatggtca gtggaatgaa tcatcagcaa
     1501 atgctttaca gagatcaggt gaacgaagga acattcaact tattagattc tcatgatact
     1561 gccaggatct tgaccctttg ccaaggtaac aaagaattga tgaagtctgt gatggccttt
     1621 atgtttcttc aaaaagggtc tccttgtatc tattacggga cagaaatagg gatgactggt
     1681 gaagatgacc cggattgccg caaatgtatg atatgggaga aggaggaaca agatctagag
     1741 ctattcggtt ttataaaaga acttgtttct ctaaggaaac agttgtctaa gattatttct
     1801 gaaggttcta ctcagtggct aatagtaaat gatcgtgaag ataagctcta tttcacacgg
     1861 aaactagagg gacagatcat ctatgtttac tttaatcagt caaaagaacc ttgggtagta
     1921 gaacaggaaa atgaggtgat tcttagtcaa aattgtcagt tgttagaaga cgggaaagca
     1981 gagatacgac aatacggatt tttgatcatg tgttgaaaac tgttaccggt aacaacaaga
     2041 aagcgtttgc aaatgaagat ttgtgcccat tataataagg gtgtaacagc acgttgaata
     2101 caaaggagga aatgaagatg aaaaaaagaa gtgtgaaaca gttgggttta gggttaatct
     2161 ctttaggaat cttaggcgga ttagcggctt gtggcaatgg taactcttca gcagaagggg
     2221 aagccgatga aggaaaaacg ttaacagttt ccgttgattc tggatataaa gattatataa
     2281 acgaaataaa aaacactttc gaaaaagaaa acgatgtgaa aatcaagcta gtagaaaagg
     2341 acatgttcga tcagttggaa tcattagcgt tagatgggcc tgctggaaag ggacctgacg
     2401 ttatgatggc agcatatgac cggatcggtg cgttaggaca gcaaggacat ctggcggaag
     2461 taaaactggg aaatgaagca gcttacgatg aaacagacaa agcccaagtg acttatgatg
     2521 gaaaaatcta cggagaacct gcagtaatcg agacccttgt tttgtactat aacaaagatt
     2581 tagtcgatac agcaccatca acgtttaaag atttggagaa tctatccaaa gacagtcgtt
     2641 ttgcttttga gtcagaagca ggaaaaaata caggattttt agctaaatgg actgactttt
     2701 attattccta tggtttaatt gcaggttacg gtggctatgt atttggtgat gatggcacaa
     2761 atccttcaga tatcggtttg aataatgcag gtgctgtaga aggaatctct tatgcaacag
     2821 attggttcaa aaatgtttgg ccaaagggaa tgcaagacat aaaaagtgca ggagacttcg
     2881 ccagccagca attcatgtcc aataaaactg cagcaatcat tgacggtcca tggcaagcgc
     2941 aaacatacaa agaaaacaat atcaattatg gtgtagccaa aattcctact ctaaataatg
     3001 gacagcctta tcaaccgttt ggcggaggaa aaggatgggt agtcagcaat tatgctaaaa
     3061 acaaagacct ctctcaaaaa tggcttgatt atgtaacgaa tcaggaaaat caagaaaaat
     3121 tctttgaaat ggtaaatgaa atccctgcaa accaacaagc tagggaaaca gcaaaggcta
     3181 aaaacgatga attaacaaca gctgtgattg aacaatatga aacagctcaa gcgatgccaa
     3241 acatcccaga aatgggcgaa gtttggacag gtgcagaaaa cttgatgttc gatgcagcat
     3301 caggttcaaa aacaccaaaa gaatccgcag atgaagcagt aaaaacaatc agtgaagcca
     3361 tagaacaaaa atactgatta aaatgataac cgtccatttt tataaaaaat ggaacaggtg
     3421 cttcagataa aagtggcaag agcgagatgg aaaattatct tgctcttgtt gccattatct
     3481 taaaagcagt ttgcggttta gcaagtttag agggggcatt cagatgcagc aagataaaac
     3541 aagcaatatc aacgaaaaaa aaatcacgct ttgttcactt attccaggga tggggcagtt
     3601 tgtaaatggc caagctttta aaggtatcgt ttttttcgcc atattcgtcc tattcattgg
     3661 tcagatgctt ctgggcggat ttcatgcatt ggtaggattg gttactttgg gaagtatacc
     3721 aatggaagat cattcattat ttattttgat tgaaggcact ttgcaattca tcattacaat
     3781 cattttcttg attttttacg gtttgaatct tttagacgct tatcgagtag cgaagatgcg
     3841 tcaagagggc aaaaaaatca atcggacgat gaaggaagtc atacataata taggtgatga
     3901 aggttttcct tatctattga cacttcccgc ttatcttctc atgattttta cgatcatttt
     3961 cccagtccta gttacattgt tcactgcatt tactaattat gacttcaatc atattccacc
     4021 agccagttta attgattggg taggggctaa aaactttttt agtatcttct ttttaagctc
     4081 atatcgtaat actttttttg cagtcttttc gtggaccgtg atttggactt tatgtgcaac
     4141 aactttgcaa atcacccttg gtattctcac agcggttgtt gctcaccaga aatttattaa
     4201 attcaaacgt attttcggta tcattttctt attaccatgg gcggtcccag cttttattac
     4261 tatcatgagt ttttcgaata tattcaacga tagcgtaggt gccatcaata ctcaagtgat
     4321 tcctttcata aaccagcttc cttttgtaga tatcagtgca atctcttgga aaacggaccc
     4381 gaactggacg aaagtagcaa ttatcttagt gcagggctgg ttaggatttc cctatatcta
     4441 tgtgatggtt acaggaatct tacaatcgat ttcagaagac ttatatgaag cagcaaaaat
     4501 cgacggagca aatgcatggc agcgcttttc aaacatcacg cttcctgctg tcttcctagt
     4561 ggcagcgcca acatttatta cacagtatac ggggaatttc aataatttct ccatgatcta
     4621 tctgtttaac aatggcggtc ccggaagcgt aggcggagga gctggttcta ctgatattct
     4681 tatttcctgg atctataaac ttacgactgg aacttctccg cagtattcta tggcttcagc
     4741 aatcacgttg attatctccg tcatcgttat ctgtgtgtca ttgctggtat ttaaaaagac
     4801 aaatgcgttc aatatggggg attaacaatg aaaaaatttc attcgagtgc tcgattccaa
     4861 aaacgacttt ctcacttttt tacttacttt tttcttttaa tactgtcagt cattatcatc
     4921 tatccgcttt tgatcacagc aagtactgcc ttcaagtcag gaaatattgc agcttttagt
     4981 ttagatcttt caagtgactg gactttagga aactttactc ggctattcag tgaaacactt
     5041 tacgggactt ggtataaaaa tacattgatc atttctgtcc taacaatgat cgtacaagtg
     5101 actgtagtaa ctttggcggg ctatacttat agtcgctatc gttttatcgg ccgcaaatca
     5161 agtttgatgt tctttttagt gattcagatg gtaccgacta tggcagcatt gactgccttt
     5221 tatgtcatgg ctttcttatt agaagcgctc gataagtact ggttcttgac aatgatctat
     5281 ataggcggtg gaattccaat gaatacttgg ctgatgaaag gatactttga cactgtacca
     5341 atagatttag atgaatctgc taaacttgat ggggcagggc atttcaggat ttttttccag
     5401 attgtattac cgcttgtcaa accgatgctc gccgttcaag cattatgggc ttttatggga
     5461 ccttttgggg atttcatgtt agctaagttc ctgcttcgaa cacctgaaaa tcagactgtt
     5521 gctgtcggct tacaaacatt tatttctgat gtgacaaacc aaagagtctc tctttttgct
     5581 gctggggcaa ttttgattgc actaccgatt tgtctattat tcttcttttt acaaaagaac
     5641 tttgttaccg gcctgacatc tggcggaaca aaaggatagg agcagagtat catgcaaaca
     5701 tttccgttaa actatttttc cgcattacgt acgccaactc aagtgtttgc gggacgcaaa
     5761 ctattatcat ggcctaaatt tttcttgata tttgtatttt tagtttcctt gatggtcatg
     5821 cctgtgactc ttttttatgc caatcagatc caagcgattc cattagaaca atttctatcc
     5881 gttcattcgc tgatcgatga acaaggaacc caaaaatttt ctgaacttga attatctgaa
     5941 actgggttac aagcatcgca acaaacgata gctgtgaccc ctgaaatttt ggtaggtgtg
     6001 tctttatctg agaaacaaca atccgatcat ggaactttta ttgattttga gaaggaacaa
     6061 tgggtgatcc aacaaaagga taaatctggt atacgccgct atacgatgaa ttatagccca
     6121 tctttccaac cagattctgt acgtacgccc gaagatttcc aacgattttt agaaagagaa
     6181 ttttatgcca gtaatcgtcc aacaatcatt ttatcttata gtttaagtct tggtcttgtc
     6241 ctatttgtca tgacgagtct cattttattc ggggcttcct ttttcttgtg gatgacaaga
     6301 aaaagccaac tttcatccat tcatacattc aaagagagtg caaatttgat gctgaatgtt
     6361 atgggaatag gttccatggc agcagcagtt gtagggttta tccactttga ctttatcttg
     6421 atgctaagtg tccaaacaac gataactgtc ttgctgcttt tatgggtttt tgtcaaaaca
     6481 agattcaaag ataagcgtgt cgaatgacaa gtttaagcga tttatgcgac aatgaatgtg
     6541 aaaaaaatga aaaataaagt agtttttgaa aaatttctga aaaaattaaa cttcttagtt
     6601 gattcttttc ttttttagta ttaacgtaat agggtagttt ttttaaggag gaaaatcatg
     6661 ttagagaaaa ctttatacaa tcaattattt tcacgttctt tctcgctccc tgtcgaagta
     6721 aattattggg acggtacaac gaaacaatac ggagatacgg acactcctcc ccaaatcaaa
     6781 atcaatatcc atgaagaaat cccaatgaaa gagattacaa gtaacgcatc tttggcacta
     6841 ggagaagcct atatggatca tcgaatcgag atcgagggaa gtatccaagc attgatcaac
     6901 gatgcttatc agcaagcaaa cagcttttta cgaggaaaag attatctaaa atggctgcca
     6961 aagaaagaaa aacatacgaa acaaaaaaac aaagaagata tccatgcgca ttatgactta
     7021 ggtaacgact tttataaact ttggctagat ccaactttga cttattcttg tgcttatttc
     7081 aatacacctg aagatacgtt ggaacaagca caaatcaata aagtccatca tatcttagac
     7141 aaactcttta tcaaagaagg cgaaacgttg cttgatatcg gttgtggctg gggaacattg
     7201 atgttcactg ctaccaaaga gtataatgtc aaggcaactg ggatcacact aagtgaagaa
     7261 caatacgatt tgattaccaa aagaataaaa gaagaacatt tagaagataa atgccgtgta
     7321 ttattaatgg attaccgcga actaaaaggc gaaacgtttg atcatatcac aagtgtaggt
     7381 atgttcgaac atgtaggttc tgaaaatctt gaaggttatt tcaaagtggt aaaagattta
     7441 ttgaaaccaa aaggaacagc tttgatccat ggaatcagcc gacaacaagg cggtgcgaca
     7501 aatgcttgga tcaataaata tattttccct ggcggttatg tccctggtgt tactgaatta
     7561 gttgataata ttacaaaaaa cgatttgcaa ctgattgatt tggaaagctt acgtcgtgac
     7621 taccaattga cattagaaca ttggacaaag aattttcatc aagtccaaga tcaagtcacg
     7681 aaagaaatgg gtgattcctt ctatcgaatg tgggatctat atttacaagc ttgtgcagct
     7741 tcatttgaat caagtaatat cgatgtgatt caatatttgc ttgttcaacc tggaaacaat
     7801 gacatcccaa tgcatcgtgc ataattgagg caaaagtact gtttaaagac tatttaaaaa
     7861 gaagctaagt tttatgatgc tccagaagtg aac
//
LOCUS       DACGDM010000111         7838 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.117, whole genome shotgun sequence.
ACCESSION   DACGDM010000111 DACGDM010000000
VERSION     DACGDM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.117"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(22..996)
                     /locus_tag="IXR05_002498"
     CDS             complement(22..996)
                     /locus_tag="IXR05_002498"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4260966.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(1076..1951)
                     /locus_tag="IXR05_002499"
     CDS             complement(1076..1951)
                     /locus_tag="IXR05_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAQ4260967.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            2081..3988
                     /locus_tag="IXR05_002500"
     CDS             2081..3988
                     /locus_tag="IXR05_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAQ4260968.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(4529..7807)
                     /locus_tag="IXR05_002501"
     CDS             complement(4529..7807)
                     /locus_tag="IXR05_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAQ4260969.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLESYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT         2208 a         1659 c         1461 g         2510 t
ORIGIN      
        1 ttctttccct cttttttttg tttattcgaa ttctttttct tccagacgga ataacggact
       61 catcggtgta ttttcatgga tgcgtttgac cgcttcaccc attaattctg aacatgtaac
      121 gattgttaag ttttctggat gacgattttc ttctgtgaaa acagaatcag tgatacaaat
      181 atctttgatt ggtgcattgt ctaaaatact tttcgcatga tcggacaata atccatgtga
      241 cgcacaggca tatacttctt ttgcgccgtt ttcttttaat acatttgctg ctcgtgcaag
      301 cgttgctcct gtgttcaaga tatcatctac catgatacat gtctttcctt gaacatcacc
      361 gatcacataa ccaccctcag ttgaagcatc atctgcatga tctacgatgg ctaatgtgct
      421 gttcaaatat tctgaaagac tacgtgcacg ctgaacaccg ctgttttttg gcgaaacaac
      481 tacgatgtca tctcccgtca gacctaattg acggtaataa tgagcaaaca acggcatcgt
      541 aaataaatta tctacaggaa tatcaaagaa tccttgtact tgaaccgtgt gcagatctaa
      601 agtcagtact cgagttgccc ctgcttcttc gatcaagtta gcgatcaatt tcgcagtgat
      661 cggttcatga ggtttcgccg tgcggtcttg cctagcatac ccatagtaag gcaatacgac
      721 attgatcgtt ttcgcacttg ctcgcttcat tgcatcgatc atgatcagta gttccatata
      781 gtagtcattg acaggtgcat tcgttgattg aacgatatac acatgatccc ctcgaatact
      841 ttcttcgata ttgatggaaa tctcgccatc actaaattgc ttcacgacgc ttttacctaa
      901 ttctgttccg aacactttcg cgattttttc agctaatgga cggttgccat tcaaactaaa
      961 aatcttcaac gtgtcatcct gatacttatt actcatgtag tcctccccaa aacttctcta
     1021 ttcttcgata gtttaacata tttttccaag attttctgtt aatttcagca aattcttaag
     1081 gaagtgaaac tgttccgtta ctccaactgg caggaatgac tttatgataa tcgccccagt
     1141 tgtcgtgtac tttgtaataa cgttctcctg tttcagtttc aaaataagcg tacgctgtca
     1201 cccaatgatt gccatatgta ctgccaagta ctttcaaaat accaatcatc acaggtttgc
     1261 cttcacgtat acgttttgta gctcgctgcc atgaacctag aagagttgct cgtgcacgct
     1321 catgattgcc attcttcttt aaaaaactag aaatccctgt actaacctga aaaggaatcg
     1381 taggaagtcc tagtggttgg atctggctac gcaatgcctt cgtcaaaacc aacgaatcag
     1441 ccgtattttt cttgcgaatc tcatttggaa gcatccaccc cttacgatag tcttgataat
     1501 aggcaaggag aactgctgcc gcgtaagtac cacaaagata gcctgagggg gtagcccatt
     1561 tcttatacct caaaaaacgt tcttctggca atcccaccca gcaatttgcg agttcctttc
     1621 ctgacctttt ttcttcgatc aaaacgggaa tatcttcttt tctgttgatc catctagata
     1681 actcgattgg ctcttcattg atcagcttcc attttttaca agaaagaccc tcttgataag
     1741 tatattttgc tggagaatat tctaccggat gtcctgattg atcgataatc acataacttt
     1801 gatcttcaaa aaccagagct aaaaaaagca atttactttt tcttgactgc agctgctgag
     1861 tgctggctaa ttttttaatt tttttatcta ctttgaaata taaaggttta tccactactt
     1921 gattcagttg ggatcgcctc ctttttttca ttataagtga aggattgaaa aaaacaaatc
     1981 agtttgattg ttcgaatttt caatttttta tgttctattt gttaattcct tcattttgta
     2041 agataatggg cacacgaaac aaaaaaggag cgatcgatga atgaacaaag aacgattgaa
     2101 acaagatttc tatgaagcag tcaatgaaga atggcaaaaa acagcaaaaa tccctgcaga
     2161 taaaccagct acaggcggtt tccaagattt agttgacggg atcgaccaac ttttgatggg
     2221 agaaacagac gatctgcttg cccatccaga aaaagtgtct tcagaaaaaa tgaaacattt
     2281 ccttgcatat tatcaactgg caaacgatta tgaccgaaga aatgagttgc atgctcaacc
     2341 gcttcaacct ataatcgaaa aagttgaatc attgcagtct ttcgacgaat tgaataagca
     2401 atttccagaa tggctgttgg atacattacc attgccattt aatctggatg tagatgcaga
     2461 tatgaagaat gcgcaaacga acgccttctt tgcttatccg ccttctttat tccttccaga
     2521 taagacgtat tatgcatcag accatcccaa cggtgcacaa ctaataggcg ttttctttga
     2581 tatggctgtt cagttattag agcttgccgg caaagaaaaa agtcaggcag aagcaatcac
     2641 ggaacaagca gtgcaatttg ataaattgat tgctcctcat gtaaaaagtg cagaagaaaa
     2701 cgcagattac agcaaaatgt ataatccgca atcttttgat acatttatta aatacacaga
     2761 taaactggac ttgaaaaaac ttgtcacggg tttgattggg acaactccag ataaagtgat
     2821 cgtaactgat ccagtgtact tcgatcattt gaatgacatc ctgacagaag ctcattttcc
     2881 gttattcaaa agctggatga tcattaaaac agtacgttct cttagtggtt atctatcaga
     2941 agaattccgc caagtcagcg gaatctattc tcgcgtattg tctggaacag acgaagcaat
     3001 gcctcagaaa aaagcagcgt attaccttgc ctctggacaa ttcgatcaag tagttggcga
     3061 ttactacgga aaaaaatatt ttggcgaagc tgctaaaaaa gacgtagaac aaatggtgaa
     3121 aaaaatgatc gccgtttata aaaaacgtct agaagaaaat gactggcttg gggatgcaac
     3181 aaaagaaaaa gccgtcataa aattaaataa cttaggtatc caagtaggct accccgataa
     3241 gatcccagca ttattcgacc agttcaaaac agtacctgca gatcagggtg gtactttgct
     3301 ttcaaatact cttgttttca gcaaactcac attaaaagat cgtttcagca aatggaacaa
     3361 accagtggat cgttcagaat gggaaatgag tgctgacacg gtcaatgctt attatcatcc
     3421 atttcggaat gtgatcgtct ttccggcagc gatccttcaa gcaccatttt acagtctaga
     3481 acaatcaagc tctgctaatt atggtggaat cggagctgtt atcgctcatg agatttccca
     3541 tgcatttgat aataacggcg ctttatttga cgaatatggc aacttgaaca actggtggac
     3601 agaagaagat cttacacaat ttcaaaacaa agcacaagca atgatcgaag aattcgatgg
     3661 tctgcctttt gctgacggaa aagtaaacgg aaaattaacc gtttcggaaa atattgctga
     3721 tgcaggcggt ctaagctgtg cattggaagc agcaaaaacg gaatcagatc tttctatcga
     3781 ggaattcttt gtcaattggg caacgatttg gcgtacaaaa gcaaaaaaag aataccaaca
     3841 acttttactg caaatcgatg tccatgcccc tgctaaactc cgagcaaacg tgcaaccaaa
     3901 aaaccttgac gaattctatg aaacatttgg tatcacggaa caagacgcta tgtatctagc
     3961 gccagaaaaa agagtgcgaa tctggtaaga ggttgtgcca gaagtggtca gcttcaagaa
     4021 ataagaagga atttgggaaa atcgcttctc aaatttttgt gacatttcgg cttatttttc
     4081 gaagaagtta cttctggaat accatgtatt agaggttgtg aaaaagctgc ttagtttcaa
     4141 gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt tgacttacta
     4201 ccgagaaact ggcttttgaa caccgtttat cgagaggttg tgaaatcagc gtcctgacct
     4261 gagtattaga gaaaaaaacg gaaaaatagt tcctcatatt ttgccgtttg ttgagctaat
     4321 accgagggtc agctgattga acaccgttta gtggagagat tgtgaaaaag ctgtcctgca
     4381 tcaagtaata agaacagcca atcaaaagca gcaaggagaa cctcatctat aaaaagatag
     4441 aaggaagtga gacatctatt ggtctcattt ccttctattt ttactttcct cagtcaattg
     4501 ttttacatca taaaaggaga aattccactt atttttttcg ctgtttcatg acataaacaa
     4561 ctacaccgat taacaaaatt cctccagcta atgctagcaa cgggttatta aattctcccg
     4621 tttttgggag tccttgagtg ccattttttt cactttcttt tgctgtccta tccggatgag
     4681 aaggttttcc atttggtttt ccatttggtg attcatttcc tggattttct ctttctggtt
     4741 tgtcatttcc cgggggcaca tcggcagttt ctcgcacagt gatcgctttt tgctgggtaa
     4801 cagattctgt atgagcagac catttttccc catcaaatat ttccgaacga taagtgactt
     4861 ctagcgtata ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta gaaaattgag
     4921 cacttgactg tgtttcaacg atttggatct tttctgggaa ataacgcata tcttcaaaga
     4981 caggcgttcc ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc ttcagttcaa
     5041 tgatatttcc ttctgcattc tccgccacac catttgcttc ttgtataata atcggattat
     5101 tttgttcatt tggttttgtc tgatttggtt cttgtacgat tgcatactct ggatattccg
     5161 aagacggtga ggtttctccg tcaaaaatag cacctacaga taatggaaga ccatccactc
     5221 tttccttttc tgtttgacga ttccccggtt taatctgcat cagtccatga acatggatac
     5281 ttccattttc atagcgcgta acaggctgct gaccttcttt cgaacatgta tttagagact
     5341 cgatccaatc ttttgatatg gtatgtccaa gagtattttc tgattgtttc tctcgttcat
     5401 tccaatagta gttcaacgag tggtagattt gatcttcgtt ttgattcaat gggcggatct
     5461 gctctctcat ctcaagattc tctgttcgga aagataagat accagaagca tggtagtctg
     5521 tgtttcctgc tgaagaggta taaagagcca cattatatga accgttatta aaacttgtac
     5581 tgctattgac gataatatct gttccgctat tggaatcgat tcctttcgca agattttcga
     5641 aagacaaact attgatcaat tcatgagggc ccgttaaaga agaaccgccc attttgaatc
     5701 cattaccgtt accttctccc tcaattcctg gtacccagcc gtttcgataa gcaactgagt
     5761 ttttgatgat tacttttccg atcgaacctg tttcattttt agcaaaaagg tcccaaccgt
     5821 catctgcatt atgatacgcg atacaaccgt caaatacatt tccttctcct attgtcagtt
     5881 tggccgcaaa tccatcggca tcttcaaatc ctggatcggc attttcaaaa gatgtacagt
     5941 tcttgactaa gttatgcgcg ggccatgctt cgaaaggatc atttgagcta ccgctgattt
     6001 ggattcctgt atttccattc cgataagcat gaatctcttc gatcaaatta tgatttccag
     6061 aaatctgtaa tcctttttgc atagctgcac tatttgtaat gtcaaaccct cgtaaacccc
     6121 agtagtgact gaacagtgtc atcccatttc cagttccttt aaaatcaagt acaggacgct
     6181 tgttttctgg atttttctct gcaatcaact gaatcgggtt ttctcttgtc ccgttaacgc
     6241 cttttggaat cgtcaatcct ctttcgaagg aataagttcc aggcgccatg acgattgtct
     6301 gcccagcata tgcgtatctc aatgcttgtg tcagagataa tggattttgt ctgcttccgt
     6361 ttcctgcatc tgacccttct ggtgttacat aaactgtcga atatttaggt ttacggtagt
     6421 ccactgtatg aagaatctct tttgtttcat aactagtcat ctctacgtat tcttctggcg
     6481 gatagttttt atctggcgta aaactgaaag taaattcgtt cgttccttcc atcagttttg
     6541 tctgataatc aaattcccga ttcgcagtga tagccaagtt ttttgcgttc ttaagcacct
     6601 ctcctgttgc tttattttta attgtcaata atccgtcagc atttgctcta aaggacatag
     6661 tatgatcttg gtttcctgaa tgattactag aggtcacagt gtaaatcgga tcaatcaagc
     6721 gagtaggtct ttcttgccca ggaggatctg tcgcaggatc tgagtaagca acttcgattc
     6781 cttctacctt gatcgtcata ttccttgctg cagcaaatcc tgcataaata accgattcat
     6841 ctgaagcgta taatttttcc cagtcataca tgatgtcaga agccatttct tctcctgttt
     6901 caggatcgta ataatatgac tctaaaccag tattcgtttt tttcatctct acgtccagtt
     6961 tagtaatcga gttcgtggcc ggaaacaaat tcccatgacc gtttccgaat atattataag
     7021 aacctgtttc tttttccaag aaccctgctg aagtctctaa aggtgttgtt tccactgaga
     7081 cactcccagg agctggcgca gcttgcggat cttcagatga tattcctgtg attgcccgtg
     7141 tccccaatcc aagtcgcatc gtatatttgc tgccgctcgt gttgaccact tcttgtctat
     7201 ccgagtccca gacatattcg atccgactgc ctagtatggc aaatgaattt gaataaaatg
     7261 cctgcccaaa caaatgattt tttggtactg cgtctcttac cattaaagca aatccttctt
     7321 gggcattcgt ataggtccaa gattctattt cgatcgtcgc ccgcatccta aagttgatgt
     7381 ctttggggat tgcttgataa taataggtca ttccatctga tccgcttgac tggaattttc
     7441 cgccgttatt cgtggaagag agccgcacgc cgtcttctaa tggttcaatg gcatacctac
     7501 tagcacttgt gctttctccg aaaacaaccc ctttccactc ttcatttgct tcttcagatt
     7561 gcttttttgt cttttcattt tctgattctt tcatcatagg atcatttcct tcttccgtat
     7621 ccatatcttc actagttctt ggtacttcct ccattgttga catcccttca atgttcacgt
     7681 gtgcattttc ttcgttcaca gactgttgtt cgttagcagc aacttcaacg acagaaatta
     7741 aaaccggggt actgagcata aggagattca tcattagcgc actgtatttt atacgttttt
     7801 ttaacaagtg tattcctccc gtaacaaatt agaaagcg
//
LOCUS       DACGDM010000112         7655 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.118, whole genome shotgun sequence.
ACCESSION   DACGDM010000112 DACGDM010000000
VERSION     DACGDM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.118"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            22..2349
                     /locus_tag="IXR05_002502"
     CDS             22..2349
                     /locus_tag="IXR05_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4260970.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2475..2804
                     /locus_tag="IXR05_002503"
     CDS             2475..2804
                     /locus_tag="IXR05_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAQ4260971.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            2844..3848
                     /locus_tag="IXR05_002504"
     CDS             2844..3848
                     /locus_tag="IXR05_002504"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4260972.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3845..4291
                     /locus_tag="IXR05_002505"
     CDS             3845..4291
                     /locus_tag="IXR05_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAQ4260973.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            4441..5256
                     /locus_tag="IXR05_002506"
     CDS             4441..5256
                     /locus_tag="IXR05_002506"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4260974.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5462..6634
                     /locus_tag="IXR05_002507"
     CDS             5462..6634
                     /locus_tag="IXR05_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4260975.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEGSSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6796..7290)
                     /locus_tag="IXR05_002508"
     CDS             complement(6796..7290)
                     /locus_tag="IXR05_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260976.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQAA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
BASE COUNT         2574 a         1451 c         1527 g         2103 t
ORIGIN      
        1 gattttttat tgagaggagg gatgaaaatg attaagaaaa ctcaaaataa aatccaacgt
       61 atatgtcaaa aacattttgt ttctagactc aaagctgtat ctaaaagaaa atacttacat
      121 cccattatga tttcgatcat cttgattttt actttcttag ggagcttatc aagtatttat
      181 gtaaacgttt atacagaaac gtcaaatttt gctaaccaaa cgacagagga gacaaatagt
      241 ccaccctatt ctgaaataca gtccatagaa agcaccaatc agtctagcaa caacgagaca
      301 acctcaacca catcctcgac tcaactgatt gatccgacag aaaaagaaat cacagcagca
      361 aaagcagcag gggagaaagc ttattcagaa acaggtagaa gccagacatt tagtactgtt
      421 gcggccactg cgaatttcaa cggacatacc ataccagatg gatatacagt gatatatgcc
      481 aaagatggag tcattgttgc ggttaacgga tcgatgagtg cggataaaac tgcgttacaa
      541 ggcgtaacca aagcaatcgc ttttattgat aaccgtccag atatccataa tctgtttatt
      601 ggctccacag taaatggtac tactatcaca ttcccaaaaa gtatctatat gggggtggct
      661 accgctggaa atacgatcga ttcagttaca cccaatgcgg ataaaagtta ttcttttaca
      721 ccctcaacat ggggagggct tcctgccgga ggaggtatga gtactttttc aatcggtata
      781 cagttagcaa atgatattcc attcacgggg tactcgatca aaaatgggca gatcgttgat
      841 ggtaagggaa atgtttcaaa ttttccaacc tatcaagcag caacggttca ggtcaatgcg
      901 aatcggacag gaactttttc ttatacagtc aatggtggag cagcaaaaat cggaacgtac
      961 gggactacat tatctggaat ccatgtgggt gacaaagtgg ttatcactcc aacagcagta
     1021 acgggctatt cttttgcaca aacaaacggt tctttcacag ccctagaaag taacgtcgat
     1081 acggtgacct atacaggcaa acaaacacca atcactatta agtatcaaga ctattttgga
     1141 cagatgattg ctccttctaa aataatgaat cttacttacg gaagtgctgc acaagacctg
     1201 acgactaata cgcctactat caacggatat acctttacag ctgtttcagc gatagaaaca
     1261 aagaaccaat cagcaatgag tgttttagct agtttagata caaatggaaa tgtaatcgta
     1321 aaggacgcaa atggaaaaca gatttctgaa gtcatcctat attataagac aaatgcaaca
     1381 gtatcaatca atgcaaatgg cagtaagtac tatgatggtc tttctgttgt accgatcgtt
     1441 aaatatgcct ttaatgataa aacagaatca acatcccttt taaacaatga tctcagtatt
     1501 gatcaaatca catggaatcc aactgatttc aaagcgatga atgaaaaggg agttgaagta
     1561 actgcgccta ctgaaattgg aacctatacg tcttggcaat tgacaaaaag cggactagct
     1621 aaactagctg ccagaacaaa ctatttattt actatcgtgc agacatctga tgtctatacg
     1681 attaagcaaa tcagcggtgc ggtagagctc agtggcagta agacatatga tggaaaagca
     1741 ggtgtcccgt caatccatgt caagctagca gagggtgtca ctagttcgct tactccagta
     1801 caagtggcac ttagcagtat ggattacaca gcagatgcac aatcagcaaa aaatatggtt
     1861 aatgctggca gctatacaat taaactaacg aatagcggaa tagacaaagt caaagcagca
     1921 aatcccaagt tgtcatttac tgatatagcc aacacatcag gaacttatac catctataaa
     1981 gctaacgcag tgattactgt cgatgacgct gcctttaatt atgatgccca aagtcactcg
     2041 atttcggttg gaaatctcca cgttaccggt gttgtcttag gcgaatcatt ggattatacc
     2101 ctaacagtta acagccggac agatattgga tcacaaatag taacgattag tttaggcgaa
     2161 ggaagtgtaa acaataatta tacgattatc gcaacagata ccgctaagtt gacgatcaat
     2221 ccgactctct tgcttccttc gacaggtggg ataggtctac tgccctttgt ctttttagga
     2281 ctgatcttta ttttttctgg cttcttttat tttatccatc gtaagaaaaa agcaggtgaa
     2341 cagcgatgaa aaaaacaaaa aatgtacgtg tggatatatt tgctgttctc ttttttatcc
     2401 tactggtctt ttttataggt tctccgactg tgtcagctag agaatcacct attacattta
     2461 ctttgcataa tcgaatgttc gaaagcgata agatgccaag tatcagtcaa aacgacggaa
     2521 taaatatccc ggataacttt caaggagtaa aagggttgaa cggcgttact ttcgctatat
     2581 atgatgtctc ggatgaattt tacaagctgc ggtcagaagg aagtagtgtg gaagacgcac
     2641 aaagaaaact agcacaaaaa agtgatagtg aaaaaatact ggcagaaaat gtgacaaaaa
     2701 cagtagacga ggaagagggc attgcttctt ttagtgcatc ggacaaagat gagcaaggtc
     2761 gtgacgctgt ttaccgattt acggaaataa agacttcaga ttaagtaaaa gaaaaatcag
     2821 caccatttgt cgttgtgctt cctgtgacag attcatctaa tcataaattg acgaccatcc
     2881 acttgtatcc aaagagcgaa caaaaaatac ctgctgcact cacattaaca aaaacagtag
     2941 agaataagca gacagatttt gcagatgggg ataaagtccc ttatctcatc accgtaacaa
     3001 ttcctgagaa catcaacgag ataggaacct atacgatcaa agatacagct gatcctcagt
     3061 tatggctaga accagaaacg atcgattttt tgattggtgg agacaagatt catacatttc
     3121 acacacaaaa aataaaacat ggttttgtct tatcagattc tggaaaagat cttagttcgt
     3181 ttgctggaaa aaaattaacg atccgttacc aaatgacatt gaaagaaaac agtgaaaaaa
     3241 cgacatttga taacgatgta cgtttgacga ctgacaatca aacagtagaa acacatcttg
     3301 ccatccaaac aggaggcaaa caatttgtca aagtggatcg gcaaacgaaa caaaaactag
     3361 cagatgctca atttctagtc aaaaaaaatg accaatactt agcgcaagaa aacgggataa
     3421 atcattgggt agccaaagat gattcaagag caacgatttt tacttccagt aaagatggaa
     3481 cattttctgt ccatggattg tcttttggaa gttacgaact agtggagatt aaaccgccta
     3541 aaggatatat attgagtcaa tcaaccattc tctttgaagt tgaaaaaggc agttatgatc
     3601 cgcttcatcc tataccattg gaaatcatca acgaaccaaa agcaaatccg acgaataatg
     3661 gaaaaacgcc agttcagatg cagacaaatg gtccatcaaa tgaaaaaaat ggaggaagct
     3721 ttccaaaaac aagcgaagag atgcttggag gtttctcaat tttagggtta ttgctagtcc
     3781 tttcaacagg gacagcttgg ttttataaaa aacaacaaaa aggaaacaat aggagggaaa
     3841 taaaatgaaa aacatcaaaa caaaaatatg gacgttttta ggaactgcta tcatgctgct
     3901 tcctttcgtt ctcggcctag gaactgcaga ggtttctgca gccgtatcac ctacaccaga
     3961 aaatgttacg gttaatttgc ataaattgaa attcacttca gcaccagaaa atcaaataaa
     4021 caacggaacg gaattgacat ttccgaatag cgaaccgttg aacggcgttg aattcaacgt
     4081 atatgacatc actgctacgt actatccaag taaagacaca gcagttccag cagacgctac
     4141 acccttcgca agtgtaacga cttctggtga aggattagct aacctgactc ttccaggtaa
     4201 atctgatggg aaagatgctg tatacgtctt tgtagaaaca ccaaagcccg gtgtcgaaac
     4261 gtcgccaaat atcgtgttaa gcttacccta gaccctgaca aacctttaga cacgattcac
     4321 ctatatgcta aaaatgtcat caaagaaagc aatatcaaaa tccagaaagc tgggaacttt
     4381 tcaggggtag ataagttagc aggggcgcaa ttccagatca aaaattcaga gaatcaattc
     4441 gtgaccggtt ttgatgaaaa cactggtgtc gctctctatg atcctgctga gtcagcgttg
     4501 acattcacaa ctgatactga aggatccatc agtgtcaatg gattaataga cggcaattat
     4561 actttagttg aaacaaaagc accagatggt tatcaattaa ccaatccaca aaaagaaact
     4621 acttttatag taaaaaacgg aaaattgcaa caaacaaccg gtatcatcca tggcgcagat
     4681 gaagccaatc ttgggaatcc aaacggtgta gtcaatcggg aaaatacaac tacggataac
     4741 acgattactg tagaaaatgt ccaaaactac ggtgatttcc acttcatcaa acaagatgtg
     4801 aacacgcaag aaaaattagc cgatgcagaa ttttctattc taagagcaaa agatccaact
     4861 gttaaattaa tgaaaaaaat agcaaacctt gcctcaggag aatacccata tgcttggtca
     4921 gatgaagtca caggttctga ctgggaagaa gtgaaattga tttctgattc agaagggaaa
     4981 ttttcaatcg aagggctgaa acaaggggca tactgccttc aagaaacaaa agcaccagaa
     5041 ggctacgcat tacctaagaa tgaagctgcg tacactgaat ttacagtaga tgatgatcca
     5101 acaacttctg atgaaacaac gatcgataac caacctaaag gaatcttgcc ttcaactggt
     5161 ggtatgggga tcatcgtatt catcttggta ggtactgctt tagttggagg agcagtgatc
     5221 tatttcaaaa aacgccatca agaaacagaa gcttaaacta ttggaaacaa aaatcatacg
     5281 ataaataaac gatagtgatt caaatgggga gaaaggttgt gacaagtggt cggtctcttg
     5341 gtattcgctc aacaaacggc aaaataggag gaactatttt gccgtttgct tcgctaatac
     5401 tcaggtcaag gcgctgattt cacaacctct tcatatacat attagaaaat aggtggacat
     5461 gatgaataaa agcagaataa gaatactgga catcttcatg gcaatcattt tagtcgttgg
     5521 gatcgggatc ttttcttatc cttttgtaga agattcactg aatgattttc ttgcccagca
     5581 aatgatcatc cattatcaaa agcaagcatc gaataagaat tcagaggaaa taaaaaaaca
     5641 gcaggaaaaa atgacaaaga aaaaccaaca gttggcagag caaaacgtat caccagggat
     5701 aggcagtttc aaccaagcag ttgatgcaaa agcattaaaa gatttaccta gtaatgcctt
     5761 ttttatggaa catatgcttg gagtcatcga aatcccaaaa atcaatgtca gcttacctat
     5821 attcgatcag acaacggaaa tatttttgca aaaaggaacg tcattattgg aaggaagttc
     5881 ttatccgact ggcgggaaaa acacccatgc cgttctttct gggcatcgtg gactcccaga
     5941 agcaaaatta tttacagatt tgcctaagtt gaaaaaagga gaccagtttt tcatccagat
     6001 caatggaaag acattggcgt atcaagtaga aaaaatccaa gtggtcttac ctgacgaagt
     6061 agattctttg ggtatccaaa aaggcagaga tctcgtgact ttgcttacct gcactcctta
     6121 tatggtcaat acacatcgac tgcttgtgac ggggcatcgt attccttatc aagcaaaaga
     6181 ggcaaaaaaa gcgatccaag gaattgatca atggaaaaaa tggaaatttt ttatttggtt
     6241 tatcggtata ctacttggat caatcggctt agtttggcta ctcatcgctt atttagattc
     6301 tttggccatc gctaagcgaa actatccttt atctttttat gtaaagaaca caaacggacg
     6361 accaatcgaa ggaatggtct tttctgtaaa aacgctcaac ggcaaacact atattactag
     6421 agaaaaagtt ccatttgtga aagcttctga tgaatacgga ctagtgagat tttctgattt
     6481 aaaaggcagg aactatcgct tgcaacatga ggagctcctg cttaaaatcc atgtaaaaca
     6541 taaacattcg aaacagtttt caatgaaatt gaaaaaagga agatataaac tgcgaaaaga
     6601 aaaagaggtg tactatttga ttgagaaaga atgaatgaag atgtccaaaa aagcagaggg
     6661 aacagactaa atgaaaaaag agagaagctg acgaaatgga cgtgtaaact gctatttttg
     6721 gtttactatc tggaacgcca gcttctattt ttttatgttt cagaagaatt ttattattat
     6781 agtataactt ttgaattagt ttccataaca tttggagcaa ggggttaaac cacgagcttg
     6841 agcttcgctt aaagtggcag gggtatacgt accatttcca catttatgtg tatggtattt
     6901 tgaaccggtc ggtgtgacat agacagtttg ttcattattt tgctcaggag ctgcggcttg
     6961 tgcctgctga gaagcctgtt cagctgctgc ttgctgtcgc gcctgttctg cttgttgctg
     7021 tgcgattgct tcttgcctcg cctgttctgc ttgttgctgt gcgattgctt cttgttgcgc
     7081 ttgttctgct tgttgtcgtg caatttcttc ttgctttttc cgttcttctt ctgcttcttt
     7141 tgctttgatt gtggaatcaa ttgcagcaag acggcttgtc aactcttgtt tgttttcagg
     7201 tagcgcttgg atagctgctg aagcagttgc atagttttct tttgtaggat ttgcttcagc
     7261 ttgtgacaaa gcagattccg cttctgtcac ttttttttct agtgcagctt tttccgcttt
     7321 ttgtttctct tcttcttttt tcttttcaat ttgttctttc gatgaatctg ccgtactttc
     7381 ggagatcgtg gtactgctgc tggaagcctg agctgaactt gtgctttgag tagtagacgt
     7441 agtagcacca cacccactca acaaacttcc tgcgaccaaa aacaacgcaa ctaatttttt
     7501 cactaaattt cctccttaag taaaaaacaa ccgttttcaa taaatgtcct tttcaattgt
     7561 ttacttactt gttataataa ttgtgttatg aatagtgatt gaggaaactt aatctaatcc
     7621 cgtgttgata cacgggattt tttgctatag ttctg
//
LOCUS       DACGDM010000113         7630 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.119, whole genome shotgun sequence.
ACCESSION   DACGDM010000113 DACGDM010000000
VERSION     DACGDM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.119"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(60..788)
                     /locus_tag="IXR05_002509"
     CDS             complement(60..788)
                     /locus_tag="IXR05_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4260977.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(801..2081)
                     /locus_tag="IXR05_002510"
     CDS             complement(801..2081)
                     /locus_tag="IXR05_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4260978.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIDDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2222..2824)
                     /locus_tag="IXR05_002511"
     CDS             complement(2222..2824)
                     /locus_tag="IXR05_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAQ4260979.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3069..3275
                     /locus_tag="IXR05_002512"
     CDS             3069..3275
                     /locus_tag="IXR05_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260980.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3587..4306
                     /locus_tag="IXR05_002513"
     CDS             3587..4306
                     /locus_tag="IXR05_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4260981.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTNK"
     gene            complement(4387..5070)
                     /locus_tag="IXR05_002514"
     CDS             complement(4387..5070)
                     /locus_tag="IXR05_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAQ4260982.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5288..7474
                     /locus_tag="IXR05_002515"
     CDS             5288..7474
                     /locus_tag="IXR05_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4260983.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         2733 a         1284 c         1438 g         2175 t
ORIGIN      
        1 aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt cggttctttt
       61 tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc gtttgccaac
      121 gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat aacataggat
      181 ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt ctcatagaat
      241 tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag cgaagtagaa
      301 aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc tattttgaag
      361 atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag gatatgctcg
      421 acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg ttcgatgttg
      481 ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat ttttcctaaa
      541 ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact gtcttctagt
      601 tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc attgagaagt
      661 tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat catgattcta
      721 tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca aatataaatg
      781 ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga aaaacgctgg
      841 ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc atccaagata
      901 aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt ttgtttcaac
      961 tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac ggaatgattc
     1021 ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc ttcaatcgca
     1081 ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt atccagttcg
     1141 attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat catgagtttt
     1201 aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact tagattggcc
     1261 ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata agaccgtaat
     1321 ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt ttggtaatca
     1381 tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata atcctgttgc
     1441 atcctgactt gttgctctaa taactgatca gctaatttct tattagagat tttccaataa
     1501 taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt attcaaagct
     1561 aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata gtatgtaaat
     1621 aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa ccaagtctct
     1681 aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa gacaatgtga
     1741 aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa aaaatcgtcg
     1801 atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag cgcgtaaacc
     1861 aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc tatagcaatt
     1921 agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca agaaatcaga
     1981 atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa gatacaaatt
     2041 gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag ctcccattga
     2101 tttttaccaa attatagcac aattagcgta ttattttttt aatttttcag ggattttgaa
     2161 ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt tagttaattg
     2221 tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag tttgtaatag
     2281 gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa aagtaagaag
     2341 ctgagaaaaa taaagtaatg agagaaaaaa ttagaaacat gctgatcgcc ttctttaata
     2401 atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat ccatagcgaa
     2461 gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag atagtcaatt
     2521 gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac agcagacaaa
     2581 cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata taagaaagaa
     2641 aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga acgaccgcta
     2701 gttttccaag attattcaat aaaacttcta aggcaaattt tacttggaca tacaccatat
     2761 cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca actttatctt
     2821 tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa acgtcttttg
     2881 tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa atcttcgttt
     2941 tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt ttatgacaag
     3001 tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa ggtgatggag
     3061 ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca tttaaatctg
     3121 atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat agtgtgatga
     3181 tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg cactggcagt
     3241 tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt tgagagcata
     3301 aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta aaaaacagct
     3361 tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat actgtttatt
     3421 tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa taggagttac
     3481 ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg cttttatttc
     3541 tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc cgataattgt
     3601 gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa tgcttgccca
     3661 agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat tgccgctatt
     3721 ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga acaaacgctt
     3781 tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct ccatctacga
     3841 agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag tagaagtaaa
     3901 gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt cgccacaaaa
     3961 gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag cgagaatcaa
     4021 aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt cctactataa
     4081 agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc ccaaaatagt
     4141 gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac aaatcgtaca
     4201 agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt cgatccgcta
     4261 cactacaaat aacccgaaag caaagggaat ctttacaaat aaataatata aaaactaagc
     4321 aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt ttttgattca
     4381 ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa atgtctgagt
     4441 gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc caaacagatg
     4501 atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac ttagatagtg
     4561 gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata agttcgttgc
     4621 tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt tgattttatc
     4681 aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta atgcgggatg
     4741 ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat atagaacaaa
     4801 caagcgccag aaatgttttt ctttttttct aaaataatca attagatact ttgttagaag
     4861 aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta gccattctcc
     4921 gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg caaaagcacc
     4981 atattggata taagtataac tgtccatggc tcctccgata aatgtcagca aaagtcctat
     5041 tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg aatatttttg
     5101 tcttccttat cttagcataa acgattgaaa aaaaggaaaa attttcagaa aactaaaatc
     5161 atatcgcttc ccattttcat ttttagaaag gtctgttagt ataaagaaaa aatagacaac
     5221 gaaactttaa ataaccaact tgaaataaac aaattcaaag aagaaagatg ggaaggaaat
     5281 caatcagttg aatgaaaaag aaattctccg attacaaaaa gaattgaaac gctgggagaa
     5341 caagtataaa aagcttcaac aagtctttcg gctacaagaa gaaatcattg ctacctatga
     5401 agcggcttat ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa aagaaagtga
     5461 aggaaacagc tctttcttta aaatgatgga gaaacgttcc tataatcgct tcaatcaaga
     5521 acaaaaagca gctatcacat atgatatgaa gaaacatctt cgaatcatag caggagctgg
     5581 gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc aaaaacaagt
     5641 agacgaagaa cgcatactaa tgatcacttt tacaaggaac gctgcaaatg aactaaaaaa
     5701 acgagtagat aatttcagcc agagaaaaac cgctgtccat atcggaacat tccatagtat
     5761 cttttttagg atatacaatg aaatttgtcg aaaatttcct gaagtagcaa tgcaaggaat
     5821 acaaggagac ttttcaaagg atactgcaca aaaagtgaat gctgttttgc aacagctgat
     5881 acgtaaatat aatctttata tatttgatca atatggagaa aaaacgattg cttctcggtt
     5941 agactattgg cagaatatga acctttcagt agaagaaatg gttcagttag ttaaagaaaa
     6001 atatgattcc attgataaga atgcacgaca gccgatatca gaacgactgt atggattgct
     6061 cacggaactc caagaacaaa aaagaagcca gcaattgcta gagttcaatg atgtactcca
     6121 aaatctgaaa agcgctttgg agaatgagga gatccagcat tatatcggcc aaaaatatga
     6181 ttatctattc attgatgaat ttcaagatac taatccactt caatgggaaa tcgtgaaacg
     6241 gatgacaaag gaaaacagga tcaagttgat tgttgttgga gatgatgatc agagtatcta
     6301 tggattcaga ggatcagagc cagcatacat caagaacttt gaaaaagaat atcctaccaa
     6361 aactcttttc ttattgacta attatcgttc tcgggcagct attgtccaag gagcaaatag
     6421 attgatcagc tataataaaa atgatcggat accaaaggcg atgattccag cacaaaaaga
     6481 agcaggtgtt atggaagcct atttgttttc tgatactaaa gcagaaagtc agtggctaat
     6541 caaacaaatt cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa tcatattata
     6601 ccgatcagct tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga atattccttt
     6661 tgtactggaa gcagatagtc catatgaagg tatctttggt atcaagtctt tccaacattt
     6721 ctatcaaaaa attgttcatt ggcaaacagc actgaatctg caaaagaaaa atcaggccta
     6781 ccagcaattg ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg aatgcgatca
     6841 atacttttct cctaaatatc aaaatatagc cgttgcagat tatattttgt cgataagccc
     6901 caatttaaaa tcgaaatctg cagaaatccg agagtttgag gaagcgttgc gtaaaacaga
     6961 ccagcatcaa gaaatctatt cgcttgttca aagctatctt catctgccac gtatagctaa
     7021 ggaaatcgac cagagtgatc aagaatggat acgagaagaa gtaaagcagc atgctacttt
     7081 cagaagactc caagccttat cgcaagaaac ccaagcgaca gctaaagaat taaaaacccg
     7141 cttgattgct tacagacaag gaaaacttga tgcactatgt atccagagca ttcacaaaag
     7201 taaaggtctt agttaccgaa atgtcttttt gattggttgt aacgaaggaa gtttgcctta
     7261 taacggagcg acagaaaaga aagtaatcga ctttaatgaa ataaaagcag aaccagtgac
     7321 gacgatagaa gaagaacgaa gactatttta tgttgcgatg actagagcaa gaaatcgtct
     7381 gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga gatttatcaa
     7441 agaaaccggg agtcgtgtga aaaaaggaaa gtgatagaag agagggtgtg acagaagtgg
     7501 tcagtttcaa gaaagaagaa ggaatgtacg aaaattgctt ctcaaatttt tgtgaaattt
     7561 cagcttattt tcgaagaagc tatttctgga acacagttta ttcggaaaag ggaggtgtga
     7621 caagaatttt
//
LOCUS       DACGDM010000114         7619 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.120, whole genome shotgun sequence.
ACCESSION   DACGDM010000114 DACGDM010000000
VERSION     DACGDM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.120"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..179)
                     /locus_tag="IXR05_002516"
     CDS             complement(<1..179)
                     /locus_tag="IXR05_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAQ4260984.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAIN"
     gene            complement(192..1295)
                     /locus_tag="IXR05_002517"
     CDS             complement(192..1295)
                     /locus_tag="IXR05_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAQ4260985.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(1385..2320)
                     /locus_tag="IXR05_002518"
     CDS             complement(1385..2320)
                     /locus_tag="IXR05_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAQ4260986.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            2622..4556
                     /locus_tag="IXR05_002519"
     CDS             2622..4556
                     /locus_tag="IXR05_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4260987.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5013..5429
                     /locus_tag="IXR05_002520"
     CDS             5013..5429
                     /locus_tag="IXR05_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAQ4260988.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            5443..6009
                     /locus_tag="IXR05_002521"
     CDS             5443..6009
                     /locus_tag="IXR05_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAQ4260989.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6032..7018
                     /locus_tag="IXR05_002522"
     CDS             6032..7018
                     /locus_tag="IXR05_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4260990.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(7173..>7619)
                     /gene="scm"
                     /locus_tag="IXR05_002523"
     CDS             complement(7173..>7619)
                     /gene="scm"
                     /locus_tag="IXR05_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4260991.1"
                     /translation="TDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSA
                     SSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTS
                     NDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2188 a         1458 c         1569 g         2404 t
ORIGIN      
        1 ttattgatag cggtagtcgc taaatcaaaa actagcattc caataaaaaa taaaaaagtg
       61 tttagccaat gtatctcatg aaaaaaagcg atagagaata atacccctac cgcaaaagga
      121 aatacactag ccacctttgt tcgtatttca actacttcta aaaagatttt tagtgtcatg
      181 gttcgtactc cttattttag ttcagaacgg tcacccatcg tgtaatggga gtcctccgat
      241 aatttgaagg tgtctttgat tggatcggtc acatatactt tatcgtcttt tgtcacgaag
      301 atcgcttccg tcccgttatt caattcgctt tcgacgtatt ccagtccttt tttcacaccc
      361 attgaaaaga ctgctgtaga caacccgtca ccatcaattg atttatctgt tatgatcgtg
      421 acacttgcga tatcattgtc gaacggataa cccgtttttg gatcaaacaa atgatggtat
      481 tttttgccat ctacttctaa ataacgctcg taaattccag aggtaactaa tgttttgttc
      541 cgttctttaa tagaacctaa aacagatccg cgagccatgt tcggatcttg gatgccgact
      601 gtccagtctt ggttttcgcc tcttgggctg tggcctaaga catagacatt accgcccaag
      661 tcaacgatgg cagtggtcac tccttgtttt ttcaagactt tcactacttc gtccgtaatg
      721 taacctttgg cgattgcacc taaatcgatg atcattcctt tttcttttag ataaacagtt
      781 ttttctttgt catttagttc gatcttatga taatccacta atttcaatgc ctgatcgatt
      841 tcttcttggg aaggttttct ggcgtcatca aaaccgattc gccataattg tgtgattgca
      901 ccaatcgcca tatcgaatcc gccttgagaa tcttggctat attcgtaggc ccgcttgact
      961 aacgtgtaga cgtcatcaga aacttttact ggtttgatcc cagcttgctc attcacttca
     1021 tcgatctcag aacctttttg attgatcgtg attttatcac caagttcttt tactcgatcg
     1081 aaggcaggtt tcaatgctga ttctttgcct tcatcataca cacggatacg aacgtaagtc
     1141 cctaacaaga actgttcatc agaatatgga tctttcaata tcttggtagc tgctgaactt
     1201 tcagtggttg ttttatttgc tgagttgctg cagccagtta gcaccataaa agagatgccc
     1261 agtgtgatta aggaaaatag tagttttttc cgcatctttt tcctctcttc attttgaaag
     1321 gtgagacgac tgcctaatct ggctatcgtc ccaccctcca acttttatta gtatgattat
     1381 gtgattattt ttctgttacg atattatcta cttcgattgt ttgagtgtcg cctttttcag
     1441 ctgcattcac taattgttgt gcgtacatga tgaatgaatg tgagctgtgt gtagcacctg
     1501 taacaacttc tacattagca ggtgagccat cttcttcgcc cattgctttg acgaattcgt
     1561 cgttcagagt agggatgtaa gtttttggtt ctgtaccgct ttttgctttc atattttcat
     1621 tatattctgt atcatcttgt tttgatttac cgtctttgtc gatataatca aagtttgatt
     1681 cagttacttt gccgccagca actgtcattt cgaattgcac acggtagccg ttagagtagt
     1741 tcttttcttc aagcttgtaa gtgccgtctt tcaaatcagc accattgtcg atttcgattg
     1801 tatctgtgtt accagcttga gcagcttgga tcaattgttg tgcgtagttt tggaagcttt
     1861 cagatgagtg agtagctcca gttacgactt ccacaccgct tgcgctttgt gcttttaaga
     1921 attggtcatt caactcagga atgtattttt ctgggtttgt gccagatttt gcttccatgt
     1981 ttttgttgta ttctgcatct tttgtttttg attcgccgtt ttcattgacg ttatcatatt
     2041 ttgattcagt gattttgccg tcttttacaa ccatttcaaa gactgcacgg taaccatttg
     2101 aataattttt ttcttctaat ttatatgtgc cgtcttgcaa atctccgcca gctacaactt
     2161 ttgcagatga ttctgttgtg ctttttgcag tcgaagattg tgctgtagat gattcagaag
     2221 aagagtttga gcttccgttg tcatctgcgc cgcaagcgcc taacactaga gctgaaaatg
     2281 ctaatacggc aaatccagtt acaaaacgtt ttttcttcat tttaataccc caccattcca
     2341 tttctagtcc acaatttttc tttgtgattc attatacatt ctaatctttt tagcctataa
     2401 gtcaactatt tttgataaat aacccatgta atatttcaaa cgttttcttt cagcaaattt
     2461 cgtgaaaaaa cgctttattt taaaatttga aaaaaatcca aaaggagtta gacaaaagaa
     2521 cagaacatct atataatata tggagattgt gtaataagta tcaaactaaa agaattatca
     2581 tatattcatt atatagatag tctataagga gcggatgatc aatggcaaag caaaatattg
     2641 tcgttgtagg agcaggatat gccggtgttt cagctacaaa atacttggca aagaaactga
     2701 aaaaagaaga tgtagcaatt actctgatcg atcgtcattc gtaccatact atgatgaccg
     2761 agttgcatga agtagctggc ggacgtgtag aaccagaagc aatccaatac gatctgcagc
     2821 atttgtttgc tcgtcaaaag aatgtacaac ttgtcacaga cactgtaatc ggtatcgata
     2881 aagaacgaaa aatcgtcaag accaaattag gttcctatcc ttttgatcag ctgatccttg
     2941 gaatgggcgg agagccgaat gactttggta cacctggtgt caaagcacac ggattcaccc
     3001 tttggtcatt tgaagattct gtaaggattc gggaacatat tgagaagaca gtagcaaaag
     3061 ctgcattgga accagatgat gaactgcgta aagccatgct gactttcgtt gtctgtggtt
     3121 ctggatttac cggtattgaa atgattgggg aactgatcga ctggaaaaat cgcctagcca
     3181 aagattataa attagatcca aacgaaatca cactgatggt cgtagaggca atgccgacga
     3241 tcttgaatat gttggatcga aatgatgctg caaaagctga acgctatttg cgtaagcaca
     3301 acgtggaatt attattgaat gcaccaatcg tagaagtggc tgctgatcat atcaaattga
     3361 aagacggacg caacattccg actcacacac tgatttggac agctggtgtc aaaggaactt
     3421 ctgacgctgc tgactttgga ttagaatcag cacgcggaca gcggttgatc gccaatgaat
     3481 atatgcaggc aaaaggctac gaagataaaa acatctatat cattggtgat ttagtctttt
     3541 atgaagaatt cccaggaaca ccgacaccgc agatcgttca agctgctgaa caaacaggac
     3601 acacagccgc agcgaatatc gtggcttcga tcaaaggcgg agaaaagcat aaatttaaag
     3661 gaaactatca aggatttatg gtttctattg gtgccaaatg gggggtagct aacctatttg
     3721 ataagatcca tttaagcgga tttttagcta tcgtaatgaa acatatcgtg aatttgaaat
     3781 acttctttga tattcgttct ggttattata tgttccaata tttaatgcat gagtttttcc
     3841 atatcaaaga tgatcgcaac gtgactcgag gacattcttc tcgttacggc aatgtcttat
     3901 ggagtgtgcc acttcgtatt ttctatggtt tagtttggtt cgttgaagct tccaaaaaaa
     3961 tcattgggaa tggtgaagtg ttcaaaccaa gtacttggtt tggtgaagga tcatggttca
     4021 ctggaaacag tgtgttccct tggacatggg aatacaatgt aacagatgtt gccagtggtg
     4081 cttctgctgc tggtgatgca accacagctg ccagcggagc aggggcaagt gccggagaag
     4141 cagcgactca agctgcacat tttggtttga gttatgcata cggtgaagaa ccaatggctg
     4201 tgattgagaa gtcaccagac tggttcacaa agatcatgca agtgatcatg ccaaacaatg
     4261 atgtagcaat gttcttccaa aaattcatgg tattctttga aattgccttg gcattagcat
     4321 tgattgctgg attattcaca tggctatgca gtgcgacaac gattgtattg gtgatcacgt
     4381 tctgcttatc aggcatgttt tactgggtaa acatttggtt catttttgtt gctttcgcat
     4441 tgatgaacgg ttccggacgt gcgattgggt tggatcgctg ggtaattcca tggctacaac
     4501 gtacactagg taattggtgg tacggtagac caagttccca gtacggcaag aaataaatag
     4561 ataaagaacg ttatttgaat gcaagatttc aatagaaagg ggctgagaca aaccgtcaca
     4621 gcctcctttt tatgtaaaat taaaggaata agatgcccga gataagcctc catgagcaag
     4681 acacaggtgt cacaacctct gttacaacct cttgttataa acggtgttcc agaagtagct
     4741 tcttcgaaaa ataagccgaa atttcacaaa aacttgaaaa gtaattttcg taaattcctt
     4801 cttatttctt gaagttgccc acttctgtca caacctcttg ttataaacgg tgttccacct
     4861 gctgcttctc ggtaataagc ccaaagaatt agaaaacatg gaaagctgtt ttctattctt
     4921 cgttcttatt actcaaagca agacacaggt gtcacaacct cttgttttta tgctaaaatt
     4981 gggtgagtta atctggaaaa aggagaacaa aaatgagcct taaagaattt gctgaaaaaa
     5041 gtctgctcaa accttgggat gtttttatta ttttgctttt gactgttctt tcttttttac
     5101 cagtcatgat ttttggtctt cagcaaaaca ccgcaacagc agaaaaagaa gcggtactgc
     5161 gtgtggatgg cacagaaatc aaaacattcc ctttgatggc tggagaagag agcaacacat
     5221 atacttacaa agatgaacac ggagattata acttgatcga gatagatggc gatcgagtac
     5281 ggataaaaga agcagattgc gatgaccaga tctgcgtacg tcgaggctgg gcaacgaaaa
     5341 atggcgaaac catcgtctgt ttgccacata aattagtgat cgaagtccgt tcaacagatg
     5401 gaggtgacga agacagtctg atttattaga ccttcacaca ccatgagtaa attacaaaaa
     5461 atgatttata tttcgctact tgttgcacaa ggagtgatca ttggtttatt ggaaaatatg
     5521 atcccttatc ctttttcttt tgcgcctggt gcaaaactag gcttagccaa tctaatcacg
     5581 atcgttgcca tttttaccat gaaaaaacaa gacagcttct tactactttg gctacgacta
     5641 ttcctgacta ctttgctagg cggaacgatt tccacattcc tttatagtat gagtggtgct
     5701 ttgcttagtt attttggaat gttattggtc aagcaattag gaccaaaacg tgtcagtatc
     5761 atcggaatta gtgcggccgg cggtttcatg cataatgtcg gacagctttt gatggcttct
     5821 ttcattgcac aatcatggac agtcatgttg tacttgccag tcctttcagt tttagggatt
     5881 ttatcaggga ttgcaatcgg gatcgcagcg aattatcttt tacgacatgt gcagacactt
     5941 caacgattcc aaaaagatta tgagcaggga accaaacaaa aatggagccc aatgtttacc
     6001 aaaaaataat cgtcacacaa ggagtttttt tatgaagcta catccaatgt gggaaaacta
     6061 tcctgcttta agtaaagaat tgacagaaac actaaaacgg atggaagaaa ctgtccgcct
     6121 gaaaaacaaa cctgtcgaac aagccatcaa agaaacgatc catgccggcg gaaagctgtt
     6181 gcgtcctgcc tatcagctat tgttctcaca atttggacca gagcaagatc gagacaaagc
     6241 catcgctttg gcagcttcta tcgaaatgct ccatacggcc acactgatcc atgatgatat
     6301 cgttgatgaa gcggatctgc gacgtggtca gcctaatatc cgtagtcagt ttggtaatgt
     6361 cgtttctgtc tatgcaggag actatttatt tgtctgctgt tttaaactat tgtctgatta
     6421 ctccacttcc ttgaaaagtc tccaattgaa ttctcgcagt atggaaaaag tattgaatgg
     6481 cgaattaggg cagatggatg atcgctataa ttatgaactt tctgtaaaag aatatttgga
     6541 aaatatttca ggtaagacag ctgaactgtt ccaattaagt tgttctgttg gcgcttttga
     6601 aagtggaaca agcgagcgct tcgcaaaaaa agcaggagat atcggacttt ctatcgggat
     6661 ggcctttcag attatcgatg atattttaga ttatacaaaa gagagccagg aaatcggcaa
     6721 acctgtacta gaagacatgc gtcaaggggt ctattcttta ccgttgatct actctttgca
     6781 aaaaaacaaa ccaaagctac taccttattt agagaagaaa gcggcaatga cagaagaaga
     6841 tgtcgacgcc gtacgcaaaa tcgttgaaca tacaggaggc gtggaagaag ctaggaagtt
     6901 agcggcctct tacacagaaa aggctttgaa ggaaataaag aaattacctg ccacctctct
     6961 tcgaacaaaa gagaatctct tttcccttac ccaactgatt ttggatcgca aagactgaat
     7021 agggaaaggt tcgatacgta aataaatttc tcagaaggaa atctacgtgt tttttgacaa
     7081 attgaattgt agttcttgta tttatgataa aaagcaaaaa taaagagcaa cgtccgttag
     7141 cgacgttgct cttttttatc ttgaatattt ttttaccttt tcgatttctt ataactcata
     7201 aaagtgattc ttaaaccgat tacaagtaat ataacgcctg cgagtgttat ccaattattc
     7261 gattgacttc cagttttagg aagtgctctt tttgatttgt ttccattgtc attgcttgtt
     7321 ttattagtta agttaaagtt cgtcctgtta tccgaacttg tttttgagaa ggagacactt
     7381 gcatgacgtg tatcgcttgt ggtagacgac gtgtctgtac tatcgcttga agttgatgaa
     7441 tctgagctat cacttgtggt agaggatgta tctgtactgt cacttgaagc tgacgtgtcc
     7501 gtgctatcac ttgtagtggt agatgaatct gagctatcac ttgtggtaga ggtagtatct
     7561 gtactgtcac ttgaagctga cgtgtccgtg ctatcacttg ttgtggtaga tgtatccgt
//
LOCUS       DACGDM010000115         7533 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.121, whole genome shotgun sequence.
ACCESSION   DACGDM010000115 DACGDM010000000
VERSION     DACGDM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.121"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(215..892)
                     /gene="nth"
                     /locus_tag="IXR05_002524"
     CDS             complement(215..892)
                     /gene="nth"
                     /locus_tag="IXR05_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAQ4260992.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(899..1597)
                     /locus_tag="IXR05_002525"
     CDS             complement(899..1597)
                     /locus_tag="IXR05_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAQ4260993.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            1865..3049
                     /locus_tag="IXR05_002526"
     CDS             1865..3049
                     /locus_tag="IXR05_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAQ4260994.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3055..3498)
                     /locus_tag="IXR05_002527"
     CDS             complement(3055..3498)
                     /locus_tag="IXR05_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4260995.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(3724..4011)
                     /locus_tag="IXR05_002528"
     CDS             complement(3724..4011)
                     /locus_tag="IXR05_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4260996.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4182..5534)
                     /locus_tag="IXR05_002529"
     CDS             complement(4182..5534)
                     /locus_tag="IXR05_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAQ4260997.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            complement(5807..6253)
                     /locus_tag="IXR05_002530"
     CDS             complement(5807..6253)
                     /locus_tag="IXR05_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4260998.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(6489..7415)
                     /gene="cysK"
                     /locus_tag="IXR05_002531"
     CDS             complement(6489..7415)
                     /gene="cysK"
                     /locus_tag="IXR05_002531"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAQ4260999.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
BASE COUNT         2034 a         1543 c         1238 g         2718 t
ORIGIN      
        1 ttataggtat attggaaggc attattttct acatcgggta ttttcccaat aaaaataaca
       61 acttttattt ttatcgcaat aaattgtaat aagttaccat cctagctact gagtatgtac
      121 atttactttt tcatgcaaaa aagataaacg aaacagcttt tctccataat aacaagataa
      181 ttcatacatt tatttgcaat taaagaaacc acgtctacag gcgtggtttc ttttttagcg
      241 ccttttcttt tagacgcatc cgatttttcc catcttgaca tattgatagc aaaggacata
      301 cctcgcactt gggatttctt gccgtgcaat gatatctacc aaaaaaaatc agtgtatgat
      361 gtgtctttac ccataattct tgtggtactt tccgcatcag tgtttcttct acttccatga
      421 ccgtagcatc tagtttgcag atcctcaggc gttttgagac acgttccacg tgggtatcta
      481 ctgcgattgc tggtatcccg aatgcatccc ccaatacgac atttgctgtc tttctgccta
      541 caccaggaag agacatcaat tcttctcttg acgttggcac ttgcccatcg aaacgttcaa
      601 tcagctgctg tgcacacgct ttgatgtttt ttgctttatt tcgatacaaa ccaatcgttt
      661 ttattttaag aatgatttca tcgattgaag cttctgctaa cgcatcgggt gtcggaaaag
      721 aggcaaacaa atctggcgtt gctttattca ctgatacatc tgtcgcctgg gcacttaaga
      781 tcactgcaat caataactca aatggattat tgtgcttgag ttctccatgt gcttcgggaa
      841 acattccata catcgtttct agagcttcca ttgttttttg tttgcttaac atattccgct
      901 actcctccaa ccaatttttc agtgagactt tcggcaattc ttcttgttga gctgactgtt
      961 ctacttctct ttgaagaagc tgctgttttc ttcgtttttg gtcttcttcc acttgttgtt
     1021 ttgtacgtag attttttctt tcccacgata gcaaaatgcg gtcaacgtaa ttaaaactat
     1081 aagcctgatt taatacggct tcccgcagtg ctagcttcaa aatttccggc tgataatggt
     1141 cttcttctag ccattgtccg atccgctgga actcgatcga agaaagcggg cgtccaaatt
     1201 cttgttcaaa taattgatac actgactgga tttctttttc ttgtgttttt tcttcgtatt
     1261 ttttttcttg tgtttttaaa tactcaccta atagatcata gatggggtaa agattatatc
     1321 gatctgcttt tttaccgttg acaatcgtcg tttctatctt gataaatcca tttgttacga
     1381 gacgatccag tatttgaaaa atctgatctt gtttgattcc catatccata gcaatcatct
     1441 gcaaatcagg gaaagtatct ccttcaagct gtgccatatg caactgtaga acaaataaaa
     1501 attcttcaga ttgtagaccg atcctatgat aatttttaag taaaagatta gatatgactg
     1561 tttgtccagc gcttaagtaa ttttctaaat tcaacatgat ttctcctccg ctcaatcaca
     1621 gtatacgtaa aaaaaacatg ggaagcaaga acaggtttct tttctattta cttcactgat
     1681 cggtcagatt tacaatgtcg tctacttgat ttttgtttgt tcatgttttt gatgcgtatc
     1741 ttcacttttc ggaataaata aattaagtag atttcgctgt tccttagaat gttgacaagg
     1801 aaacaaaatt actatacact atttttgttt ccaagttaac attattgcat aaaggagttt
     1861 ttacatgtac agtttcacaa ataaacattc taaagttttt ggatacgtct ctgtcttatt
     1921 cactggatta ggatttacta tcgtcagtcc tgtacttccg tttttaacgc tgccttattc
     1981 tcactccata catcagcaag ctttctatat cactttgctc atgtctgttt atgctctagc
     2041 tgccttctta tctgccccca ttctcggtag cttaagtgat cattttgggc gtcatccgat
     2101 ccttattatc agtttattag gatcaagtat cggatatttg ctttttggtt taggaaattc
     2161 gatatggatg ttgttccttg gtcgtatcat tgaaggattg acggcaggag aaatctccac
     2221 cttatatgct tactttgccg acatcacgga acctaatgaa agaaccaaag tttttggatg
     2281 gatgggtgct ttagtcggta taggaacaac gctgggtcct attatagggg gtctattagc
     2341 tgagttgggg aattctgttc ctatatttat tggagcactc tttactttct taaatgccgt
     2401 ttatggctac acatttatgc tagaaagcct tccaataaaa aaacgttcag tagatttaag
     2461 tttctcccat gtaagacctt ttcaccaatt acaacaatta ttcaagattt catccgttat
     2521 tcctttattg acagcaggtt ttgctgtttg gttggcagct ggctctcttc aatctatctt
     2581 ttctcaattt tcgattgacg cctttcagtg gaaggctggg ttggttggtt taagcttctc
     2641 tttgattgga atcttggata ctgtctcgca attgttcatt atgcctcgat tgctcaaaaa
     2701 attttcagaa cagcagatca caagaatagg gatgttcagt gaaatcctcg cctatctatt
     2761 catcacatta tctggaattc ttctactgcc gattttgttt ttatttggga ttatctgtta
     2821 tggtttcggt gattctattt ttactcctgt attcaatggc caactatcca attctgtctc
     2881 agataaccag caaggtcttg taatgggcgg tacccaaagt atacaatctc tatcgcgcgt
     2941 catcggcccg ctaatcgcag gacagcttta tgctgcagca ccatttcttc cgacggtatt
     3001 cggatttttg cttatgattt ttgcctatta tcactacaat aaaaaatagt agcttcattt
     3061 gctacttcgt ataaattctc tgtatcgacc gataaaacga aatactgtgt caaattcttc
     3121 ttttgacata ttttcaaata cagtagcatc tcgctgtacc catttttgat ggagttgctc
     3181 gtgtctattc cttatttttt gtccgattgg cgtcaattga aaatagattt cttttttatt
     3241 ctcttcgctt tgataagtgt ttatgatccc tctagctatc agtttttttg ttagcttact
     3301 gatggctcct ctagtcatgt aactagcatt cgctaatttt gtcacgttag gatcagggat
     3361 tttcccgata tgttcaatca cttctagttc atttagagta aatcctgcaa attctttttc
     3421 catttctggt ttattacgat gaataatctc attagctaaa tccagatatt cttctattag
     3481 cagttgtctt ttatccattt ctacaccttc tttttctttc attatattgt ttttttgttt
     3541 cctattcaac aaagataaaa atattttgta ggaaaaccca atctgaaacc aagaaaaaaa
     3601 ggggttgaca aagcttgtca taaccccttt ttctgattaa aagatagtaa agagacagtc
     3661 atcggtaatt gtgatgattt tttgtcatca cttaaggatg agcggccttt tcaaaaactg
     3721 tctttaaaga tcatcatcag tttctagcac atatggctga ccttcatatg tgtactctgt
     3781 attcaatgtg ccgtcatttt catctgagta gatgcgtcta ctgaaaggaa aacgatgaga
     3841 aacattatct ttggcgtcat ttgctggcat cgtgtaatat tcctcttgcg tttcattcaa
     3901 ctgagagagt acttgatctg ccaactcatc aatattgatc gttaatttct tcgaagcact
     3961 tttataatct tctaaaaatg catcttgttg gacaaaatat tctttattca tcttctttct
     4021 cacctttctt ttcaaaatca aataaagctg cttgttcttt tatgtaacag ctttatcttt
     4081 gctgcttatt gtgacaaaaa attcgaagaa agacaactaa ttgtactttt cacaaaaaaa
     4141 gacagagggt cgtgacaaaa ttgtgtcaca accctttttc tttattgtgc agtttcgatt
     4201 tcgcctagcg ctgcttgtgc aagtaggttc aagtaattcc atgggcggtc aaaatgtggt
     4261 tggaagaaga aatctgaaag tgcgagatct tctacagtca ttttattttg aacagctaaa
     4321 gacatggtat ttgctgattg tgtaatgtcg tatttggaca tgaactgagc acctacgata
     4381 cgattcgttc ctttttcata gactagctcc atcattactt tttcagtagt tggcatgaac
     4441 tctggacgat aattatcttc aaatacagtc gcttggactt ctagatcgtt caaagttgcg
     4501 ctttctttgg tcacacctgt cgaaccgatc gtccagccaa ataggtaaag tcctgaagtt
     4561 ccttgagtac cacgatacgc cattttatga tctgtcaagt tatttcccac aagcaaacct
     4621 tgacgaacgg catttgttgc caaaggaata tagttttgcg tgccacttgg attgtagttg
     4681 actactgcag agtctccagc tgcaaaaatg tctggattac ttgtctgcat gtattcattc
     4741 actttgattg ccccgtttgg cagtgtatct acttttcctt cgatcagttt tgtatttgga
     4801 cggaagccca cacataaaat gaccatatct gtatcaaatg tatctgttgg tgtagctact
     4861 tgtttcactt ttccttcttc atctgtgata aattcagtaa cattttcgcc tagcgcaaga
     4921 gtaacaccgc ggtctgtcaa ttctttttct aagatatctg tgaatggttt atctagatat
     4981 ttattcaaga tgcgatctaa tccatcaatc aatgtcactt gttttccaga ttcgacaaaa
     5041 gcttctacta attcaatacc gatatatcca ccaccaacaa ttactacacg ttttgcttct
     5101 ttcgcttgtg caataatttc atttgcttga ttgtagtttt tgcataggag tacatttttc
     5161 gcatcgattc cactaatcgg tgggataata ggccatgaac cagttgtcat cactaattta
     5221 tcataagaaa ccgtttctgt ttctcctgtt ttcagatctt ttgccgttac tgttttattt
     5281 tctgtatcga cgtctgttac atcgtgttcc attttaactg ttgctcctaa tgaagataat
     5341 tcttcaggat ttgagtagaa caagcctgct gggtccttta ctactccgcc gacataaagt
     5401 gcgataccgc aagataagaa agaaatattg tcatttcttt catatactgt cacttctgct
     5461 tctggatgat tttttaaaat actttttaca gctgcagtac ctgcatgagt acagccaatt
     5521 actactactt tcatttatgg tccctccgat taacattttg tccttcgaca aaactactat
     5581 aacagaaata aaacggatac aacagtttaa tgcttgtgaa ttcacaaagg tttgtttgta
     5641 gtttcattcc ttttcaagca taagaaccca atatctacaa gattcttatt ttaataatat
     5701 tcacttttat atctaagatt gtgaataaaa gacaaaaaaa taaaaaagct agcgtttttt
     5761 ttacacagct agcttttttt aggtataaca cttgtagaaa ctgtttttac atttgcgcct
     5821 tttttgctga ctctttacaa tccggacaga gtccatacaa ttccaaccga tgttcattaa
     5881 tctcaaaatc agtcagtctg cttgcagcca tttctatatc ttcaagccct gggtaatgaa
     5941 aatcaacaat cttaccgcag ttttcacaaa ttacatgata atgacgcttt gaactgaaat
     6001 caaatcggct agaagcatcg ccgtacttca tttcttgaac aaatccaatc gaagtaaata
     6061 agcgaaggtt attgtaaaca gtcgcaacac tcatatttgg aaaccgatgt tcaagtgctt
     6121 tataaatctc atcagccgtt ggatgggaat gatgttcaat caaatattct aaaaccgcgt
     6181 accgttgagg tgtgattcga atgttctctt tttttaactt ttcgataacc tcttcgacta
     6241 acttattttc catgtaaaca ccccacgttg ttattctcgt cttatcatac tatttttaca
     6301 ttttaaaatc cacttaacat gaaaagaaaa ttcaatttta ttgtatttta atgaaaaaag
     6361 acgtaaaaca gtcgcgttca ctattctacg tctctattca aataattttt ctcatcataa
     6421 atttttgtgt gttcttttca tctttaaaag ttttttacat aaacctatct ggagaaaaac
     6481 caagtgcctt atatctcttg gtaaagggct gtagataaat aacgttcacc attgtcggga
     6541 accacagcta ataccttctt gccttttcct aattcttttg cgacttttag cgcggcagca
     6601 attgcagcgc cagatgagat gcctactaaa atcccttctt ttcgcccaac ttctctagct
     6661 gtttccatcg cttcgtctcc actaatagaa aggactttat catacacaga agtatccagt
     6721 gttttaggaa caaaacctgt accgattcct tggattttgt gaggtcccgc ttctttccct
     6781 tctaaaatag cagattctgc tggttctacc ccgattaatt cgattttcgg atacacacgt
     6841 tttaattctc ggccagcgcc agtgatcgtt cctcctgtac cgatacctgc aacaaacgcg
     6901 tccaagccat ttactccaaa tgcttgatgt atctcaggac cagtcgtctt ctcatgcaca
     6961 agaggatttg cttcattttc aaattgtaat ggtaaaaagt agccgttttc ttttgccaaa
     7021 cgttctgctt ctctgattga tccagaaata ccatccgcac caggagtcaa aatcaactct
     7081 gcgccgtacc ctttcatcaa taaacgtctt tcgatactca tcgtctcagg catcacgatg
     7141 attactttat atccttttgc aactcctacc atcgacaatc cgattcctgt atttccagaa
     7201 gtaggttcaa tgatagtatc acctggtttc agtagaccat cgtgttctgc tttttctatc
     7261 atacttaaag caatacgatc ttttacactt cctcctggat taaaaaactc aagctttaca
     7321 aaaacatctg ctgaatcttc tggtacgatt ttatttaatt tgacgattgg cgttttgcca
     7381 atcaattcgg tgactgagtt atagatagct gtcatcttca attcctcctt gtctttgctc
     7441 ttcttactta tcataataca atctgttcat ttatggcgag tgattcgtct ttgactagca
     7501 aaaaaaagac aaagatatac catatatggt aat
//
LOCUS       DACGDM010000116         6952 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.122, whole genome shotgun sequence.
ACCESSION   DACGDM010000116 DACGDM010000000
VERSION     DACGDM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.122"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(83..541)
                     /locus_tag="IXR05_002532"
     CDS             complement(83..541)
                     /locus_tag="IXR05_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAQ4261000.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(554..1879)
                     /locus_tag="IXR05_002533"
     CDS             complement(554..1879)
                     /locus_tag="IXR05_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAQ4261001.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1896..3308)
                     /locus_tag="IXR05_002534"
     CDS             complement(1896..3308)
                     /locus_tag="IXR05_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4261002.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(3325..4089)
                     /locus_tag="IXR05_002535"
     CDS             complement(3325..4089)
                     /locus_tag="IXR05_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAQ4261003.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4193..5068)
                     /locus_tag="IXR05_002536"
     CDS             complement(4193..5068)
                     /locus_tag="IXR05_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4261004.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5323..5407)
                     /locus_tag="IXR05_002537"
     tRNA            complement(5323..5407)
                     /locus_tag="IXR05_002537"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5371..5373),aa:Leu,seq:caa)
     gene            complement(5425..5496)
                     /locus_tag="IXR05_002538"
     tRNA            complement(5425..5496)
                     /locus_tag="IXR05_002538"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5462..5464),aa:Gln,seq:ttg)
     gene            complement(5506..5578)
                     /locus_tag="IXR05_002539"
     tRNA            complement(5506..5578)
                     /locus_tag="IXR05_002539"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5543..5545),aa:His,seq:gtg)
     gene            complement(5640..5724)
                     /locus_tag="IXR05_002540"
     tRNA            complement(5640..5724)
                     /locus_tag="IXR05_002540"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5688..5690),aa:Leu,seq:caa)
     gene            complement(5745..5815)
                     /locus_tag="IXR05_002541"
     tRNA            complement(5745..5815)
                     /locus_tag="IXR05_002541"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5781..5783),aa:Cys,seq:gca)
     gene            complement(5861..5932)
                     /locus_tag="IXR05_002542"
     tRNA            complement(5861..5932)
                     /locus_tag="IXR05_002542"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5898..5900),aa:Gln,seq:ttg)
     gene            complement(5944..6016)
                     /locus_tag="IXR05_002543"
     tRNA            complement(5944..6016)
                     /locus_tag="IXR05_002543"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5981..5983),aa:His,seq:gtg)
     gene            complement(6019..6092)
                     /locus_tag="IXR05_002544"
     tRNA            complement(6019..6092)
                     /locus_tag="IXR05_002544"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6058..6060),aa:Trp,seq:cca)
     gene            complement(6099..6179)
                     /locus_tag="IXR05_002545"
     tRNA            complement(6099..6179)
                     /locus_tag="IXR05_002545"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6143..6145),aa:Tyr,seq:gta)
     gene            complement(6181..6256)
                     /locus_tag="IXR05_002546"
     tRNA            complement(6181..6256)
                     /locus_tag="IXR05_002546"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6221..6223),aa:Phe,seq:gaa)
     gene            complement(6292..6364)
                     /locus_tag="IXR05_002547"
     tRNA            complement(6292..6364)
                     /locus_tag="IXR05_002547"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6329..6331),aa:Asp,seq:gtc)
     gene            complement(6374..6446)
                     /locus_tag="IXR05_002548"
     tRNA            complement(6374..6446)
                     /locus_tag="IXR05_002548"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6411..6413),aa:Val,seq:tac)
     gene            complement(6462..6533)
                     /locus_tag="IXR05_002549"
     tRNA            complement(6462..6533)
                     /locus_tag="IXR05_002549"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6498..6500),aa:Glu,seq:ttc)
     gene            complement(6548..6637)
                     /locus_tag="IXR05_002550"
     tRNA            complement(6548..6637)
                     /locus_tag="IXR05_002550"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6601..6603),aa:Ser,seq:gga)
     gene            complement(6677..6750)
                     /locus_tag="IXR05_002551"
     tRNA            complement(6677..6750)
                     /locus_tag="IXR05_002551"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6714..6716),aa:Asn,seq:gtt)
     gene            complement(6760..6875)
                     /gene="rrf"
                     /locus_tag="IXR05_002552"
     rRNA            complement(6760..6875)
                     /gene="rrf"
                     /locus_tag="IXR05_002552"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2078 a         1543 c         1143 g         2188 t
ORIGIN      
        1 tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa atatcaccct
       61 atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc tttacttctt
      121 ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg atcaccgtat
      181 ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc ccttctttta
      241 cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca actgtatcta
      301 aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg gcatgtcggg
      361 taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca tcatgattcg
      421 ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt actgctgtta
      481 atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta aagaaatgca
      541 ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg atcatttcat
      601 ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta aatgcttgta
      661 aagctttttg ataagaacct tcaaagtaag catctactag taacttctct actgcaactt
      721 gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta attggctcca
      781 caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt agattcggaa
      841 tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc aacaaggaaa
      901 tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat acttcttcca
      961 caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt ccatccatga
     1021 ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca ggatataagt
     1081 aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg actgacatca
     1141 tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact tgcatttctt
     1201 ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct ttatcataaa
     1261 tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa ttcttacgat
     1321 cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca caggcattaa
     1381 tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac tctggatttg
     1441 tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca atttccaata
     1501 aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt tcttgtccta
     1561 ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat cctccaacac
     1621 gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca tccgttgcac
     1681 gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc aagtacatat
     1741 ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc aaccgttttt
     1801 cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct ccagctatag
     1861 tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa tttattgaat
     1921 tctgccataa cataagtcac ttctaagccg atgataattt gataattttt ttcagttggt
     1981 ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat ggtgggatcc
     2041 actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt ggcttttcct
     2101 ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc taaccctaac
     2161 tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg tcctaatgtc
     2221 tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc aaaaaagaaa
     2281 attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat gagataatca
     2341 acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca gacaatccct
     2401 gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa catgaaacta
     2461 aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct tcccatgatt
     2521 cctttgacca tctctttatt ttctttataa gctgctttat agatagctag acatatagct
     2581 ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc ctgaggatct
     2641 ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga tgtatagctt
     2701 cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg gatcagcaaa
     2761 cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag cagttttgca
     2821 aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac agctgcgatt
     2881 gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata agaaaaaact
     2941 actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa accggaaata
     3001 attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc ttttttcaag
     3061 gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt tttgacaaaa
     3121 ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc atttccagct
     3181 gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat caatcccgct
     3241 aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac atttgattta
     3301 acattcattt ttattcctcc tctattaaat atcctcatat gttactaact caatcaaagg
     3361 atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt ggtgggtacg
     3421 aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg cgtgacacat
     3481 gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat attcttccac
     3541 actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga aacaaggctc
     3601 aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa ccggcaaatc
     3661 atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat gagtatgatg
     3721 atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa tctgagcatt
     3781 ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat aagataagga
     3841 tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt tgccacacgt
     3901 caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt tcacagcatg
     3961 ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc gctgataagc
     4021 atccataatc ccataattca caccatggct atagccaaaa tcatccgaat taaaaatcac
     4081 ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa ataatcatag
     4141 tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta ttttaataga
     4201 ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca agttgaaatt
     4261 gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta tgtttaaatg
     4321 tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc aagcgtttaa
     4381 ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta tcataaacgt
     4441 ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact atttttaagc
     4501 tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg atgaatccta
     4561 cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc acttctactg
     4621 ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt gctgtgacat
     4681 ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat gtaatataga
     4741 tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact tcttccgcaa
     4801 aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg atcttttctt
     4861 tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta ctcactttag
     4921 cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca tcgatcaata
     4981 cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct ctatatgata
     5041 aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa tttttaaaga
     5101 caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat agtagcaccc
     5161 tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat cttttttact
     5221 cgttttatga taatacttgt atcgaattga tttggaggta attacataaa aacaaaaaaa
     5281 atatagcaac tctctataag aaagttgcta tattgataat tataccggcg gccggggtcg
     5341 aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc aattccgcca
     5401 cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg catgagggag
     5461 tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga atgatgggaa
     5521 tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc acattcgcca
     5581 tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat cttagtcaat
     5641 accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg agtccagcgc
     5701 gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg taaccggatt
     5761 tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata ccgccattat
     5821 actattatca atctataaaa taaagaataa attatagaaa ctggggtagc tggattcgaa
     5881 ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc caagaataaa
     5941 aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg tgcgttaacc
     6001 acttcgccac attcgccatg gcaggggcag caggaattga acccacacta acggttttgg
     6061 agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg gattcgaacc
     6121 actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc tactcctcca
     6181 tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt tgctctacca
     6241 actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg acggttccga
     6301 cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc tacaccacgg
     6361 aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt gtaaggcaga
     6421 tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta cgggattcga
     6481 acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg gccaggtaaa
     6541 tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat ctacatgatt
     6601 tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag ctcaatactc
     6661 tttctcaaaa tgagaactcc ggcagtagga ctcgaaccta cgacatcatg attaacagtc
     6721 atgcgctact accaactgag ctatgccgga ataacatcag cgtggcgacg tcctactctc
     6781 acaaggggca acccctcact acaatcggcg ctaagaagct taacttctgt gttcggcatg
     6841 gttacaggtg tatccttctc gctatcgcca ccacactgtg gtgttatctt ttattgagta
     6901 aattttgttc actcaaaact ggatttgaag tcacataagt ttttttccga gt
//
LOCUS       DACGDM010000117         6883 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.123, whole genome shotgun sequence.
ACCESSION   DACGDM010000117 DACGDM010000000
VERSION     DACGDM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.123"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            18..908
                     /locus_tag="IXR05_002553"
     CDS             18..908
                     /locus_tag="IXR05_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAQ4261005.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(981..1805)
                     /gene="nadE"
                     /locus_tag="IXR05_002554"
     CDS             complement(981..1805)
                     /gene="nadE"
                     /locus_tag="IXR05_002554"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAQ4261006.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1817..3289)
                     /locus_tag="IXR05_002555"
     CDS             complement(1817..3289)
                     /locus_tag="IXR05_002555"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAQ4261007.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3926..4288)
                     /locus_tag="IXR05_002556"
     CDS             complement(3926..4288)
                     /locus_tag="IXR05_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4261008.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4511..5263
                     /locus_tag="IXR05_002557"
     CDS             4511..5263
                     /locus_tag="IXR05_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4261009.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5403..6326)
                     /locus_tag="IXR05_002558"
     CDS             complement(5403..6326)
                     /locus_tag="IXR05_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4261010.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6341..6613)
                     /locus_tag="IXR05_002559"
     CDS             complement(6341..6613)
                     /locus_tag="IXR05_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261011.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2121 a         1360 c         1169 g         2233 t
ORIGIN      
        1 tttaagaggt gatatatatg caactacaaa taaacgaaga atccttaccg gtatatgaag
       61 cattagctag taaaacaagg atcaagatca tccagctact ttccaaaaaa aagatgaatg
      121 tcaaagattt ggcaaaagaa cttggagtga gcagtgctat cacgacgatg cacgtgaaaa
      181 agctagagga agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa atttcgagcc
      241 ttcgtgtcga taaaatcgat attagttttc cagaaaaaat attcaatgct tttgatacga
      301 aagaaacatc gatacctatt ggtcactata caaattatgc aattgaacca acatgcggtt
      361 tagctacgat ccatgatttt atcgggaaag tggatgaacc acgctatttt atggatcctc
      421 gaaggatgga tgcccgcatt ctctggttta ccagcggatt tgtcgagtat caggcaccta
      481 attttttaaa tacagaggat acattggaga tgttggaagt ttctgtggaa atttcttctg
      541 aatttccttt ttcaaatgac aattggcctt cagatatcac tttcagccta aatggtgtgg
      601 agctaggaac atggacgagc cctggagatt ttgctgatat ccgcggtaaa tatacgcctg
      661 attggtatcc agataatctt aatcaatacg gcttgctgaa gacgatccga attaccaaac
      721 acttgacgaa tatgaatgga gaacccttgt caaacatcac gatcaacgac atccctaaag
      781 agcaagacac ttggcatttg cgaatcgaag tgaaagacga tgccaaacat gtggggggct
      841 gtactttatt tggtaaagga ttcggtaatt acgatcagga tatcaaatta aaagtttact
      901 acagctgata tttttctttt ctattttata aaacaaaaac agccaatccc tatgaaggga
      961 cggctgtttt tgctttattg ttatttccag aaatcatcca aaacggaaat tggcaaatgt
     1021 cgtttatgtt gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg agcgggaact
     1081 tcttttcctt ctagataatc atcaatttca ttatatgtga cacctagtgc gacttcatct
     1141 gcaatcattg gtttcccatc ttcaagatct gcagtcggaa tttttgtgta taatttttcc
     1201 ggtgcattca atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg gaataatggc
     1261 aaaatgtcgg ctccaccatc accaaatttc gtgaagaatc cagtaatgtt ttctgcagca
     1321 tgatctgtcc ctaatacggc tcctgctctt tctccagcta cggcatattg cgtaatcata
     1381 cgttgacgtg ctttgatatt tcctttgtta aaatcgctga ttcccacacc tgcttcgctt
     1441 aatacttgta cttgtgcatc aacagctggt ttgatattta ctcgcagact aacatcgggc
     1501 tggataaagt caagagcagc ttttgcatct tcttcatctg cttgttcacc ataaggaaga
     1561 cgaacagcga taaattgata gttttcatct tttgtttctt cacgcatttc ttccatcgtt
     1621 agttgcgcca aacggcctgc taaagtagaa tcttggccgc cgctgatacc tagtacaaaa
     1681 gttttaagaa acggatattt tttcaaatat gctttcataa agtcaatact tttacgtatt
     1741 tcttcttttg gatcaattgt tggtttgaca cctaattcat tgataatttc tgtctgcagg
     1801 ctcatttatt ctcctcctat gcttctgtat gaagttctgc tacgcttttt ttcattcgtt
     1861 ccatgatagc cattttatgg ttccagcatt cagtagacag atcgactggg tatttttgcg
     1921 gattcaagtc tcgtttatac tcttcccata gtgaatctag attttctttt gtatattctt
     1981 tgatttcgtt tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag atatcttgta
     2041 aaactgggcg agctgtaaag tctcgaacag ttttattgat aaacgtatgc actggatgga
     2101 acatgaagat agcttcttct tctcgagggt cttcatccca taatgtcacg tagtctcctt
     2161 cagatttccc atcaaaattt cgagtgatgc gccacacttg ttttttccct ggagtagtta
     2221 ctttttctgc attgcttgat aacttgatcg tatccatcat ttttccttca tcatcttcga
     2281 tcgatactag cttgaatact gcaccaaggg ctggctgatc ataggctgtg atcaattttg
     2341 tcccaacacc ccatacatca attttagctt tttgcatctt taaattcaaa atcgttgctt
     2401 catccaagtc attcgaagca tagatttttg cttccgtaaa tccggctgca tctaattgtt
     2461 cccgaacacg cttagatata taggccatat ctccactgtc gatgcgtacg ccttggaagt
     2521 tgattttgtc acctaattct ttcgccacgc gaatcgcact tggcacacct gatttcaacg
     2581 tatcataagt gtcgactaag aacacgcagt ctttatgggt tttagcgtag gccataaatg
     2641 cttcataatc atttccataa gattggacta acgaatgagc atgggtcccg ctagctggta
     2701 tcccaaatat cttcccagca cgtacattgc ttgttgcatc tgctccgccg atatatgccg
     2761 ctctagttcc ccagactgct gcatccagtt cttgtgcccg tctagttcca aattccaata
     2821 gtggatcttc tccgatgaca gatttgatac gagctgcttt tgtcgcgatc aacgtttgga
     2881 aattgaccat attcaacagt gctgtttcta ctaattggca gtgcgctaaa ggcccttcca
     2941 cttggatcaa tggttcattt gcaaaaacta gttctccttc acgagcagaa cgaactgttg
     3001 ctttaaattc aaaattttgt aaatactcca aaaaaccttc aggatagact tctaatccac
     3061 gcaagtaagc aatatcggaa tcattgaacg tcagattctc taaataattg actaaccgtt
     3121 ccaatcctgc aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag taacattcaa
     3181 aaacagcatg taaatcagct cgacctaatt cccagtatgt ctgcatcata ttgatttgat
     3241 atagatccgt atgcagcgtc aaactgtcgt ctgggtaagt attattcatc ttgtattact
     3301 cctcttggca agttttcatt tcctacccat tataacaaaa aaaattaata ggaaaagaaa
     3361 tcttccattt tttctgaaaa agcacatgtt ttacggatat ttcttgctaa aaatgaactc
     3421 catctgctaa aactatcctt tcttattggt atttaaccta aacgagaaag aatacttatt
     3481 ttattcaatg tatccgagac acgaagaaat tagcgttttc tatttttctt acttgataaa
     3541 ataagtagat tttcctacta caatcgtagc cgttaagata ccgatgattg aacaaatata
     3601 accaaatgtc tctacaacat aatcaatggc aaaagttttt gaagcaataa tacgtctttc
     3661 cttttttgct tcttatcccc aaagaaacgg atataactta ttatgtattg aatttttttg
     3721 gaaaggcgaa ttatgacaag atataccttg cgttgaaaaa actcgcggaa aaaatatcac
     3781 acgtttttaa aaagatacaa agtaagaaag cagctgtcaa tagaatggaa acaaaaatgg
     3841 cgagacatca atcagtctcg ccttgttttt tattgtatac attagatatg gagcaggtta
     3901 ccataaagat gattattagt cgttattaaa tagaatcctt cgtatttttt tgttctatca
     3961 ctacaatatc tttatttgga cgtttgaatt gtattccggc acgttctagc tcctgtttca
     4021 ctcctacatg gactttgaca tcttctcgtg tcatttttaa aacgtgatga atcgcatagt
     4081 cgatttcttg ccttgtgatt tttttcttcg tattgatcat cacgacttgc tttttatcat
     4141 atgtgtctac caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa taattaatag
     4201 ccgtattccc aaaaaagaat tccactactt taggataaaa tgtcttaata tttaaattac
     4261 tattcacagg tgtttcgatt agcttcatct cattcctctt ttctatatag tcgatttaga
     4321 tccaatctta agttatgtta ccatctttcc tagcattaag gaatcggtta caattgaacc
     4381 tttaaagaca aaaggattta ccttttatca cttaatagta taacataatt tcatgagaaa
     4441 aaaatacaat tttttcttga ccatctcgtt acgtaaagga ttatgcttac atttgtcagg
     4501 aggaaaaata atggagtaca caataaagaa aatgtcagag atatcaggag tcagtccgag
     4561 aaccttgcgc ttttatgatg agattggact gctaaaacca gctaggatca attcttcagg
     4621 ttatcggatt tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat tttatcgaac
     4681 aatggcattc aagttggatg atatccaaga ggtcttagac aatccatctt ttgaccacca
     4741 gaaagcttta atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa tcgataccct
     4801 cttgacaact gtccaacaga cacttgatat gtacgaagga ggaagaaaaa tgagtgacaa
     4861 agaaaaattt gaagggttta aacaacaaaa gttgaaagaa aatgaagaat cctatggaca
     4921 agagattcga caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa aatggatgaa
     4981 tatggataaa gaaacgtatg aagaaatgca aactgttgaa aagcagatgt tatttgatct
     5041 cactctttac ttaaaagaac cagaagatga aagcttagca gaccgtatct tccaagctca
     5101 taagaagtgg ttatcttaca gctggcctga atatcagcca aaagcgcata aaggactagg
     5161 aatgatgtac gaagccgatg aacggttcac tgcatattat gacgagcgaa gtggtcatgg
     5221 tgcagcaaaa gctttaaatg aaattatcca aaaaaaggcg taatctttta catgatccaa
     5281 caaaaaagta cacgtaaaat gacctaataa caaaacagca gacacccaag ttagattttt
     5341 atgctaactt ttggtgtctg ctccattctt tcacaagttt tttcatccta ctttaaatat
     5401 attcatcgtt gaataaacgt ataaggtatt ttcactttat cctttttttc tgtaagaaac
     5461 aattgaaatg ccatttctcc gcaagcttcc agatggtggt cgatggttgg gaaaccaaga
     5521 agctcgctga tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc ttgcagatag
     5581 ctttgcaaga tgcctgctgc aaccatatcc gaatttgtaa agacaccatc aactccaagc
     5641 tctttaaaaa agaagcctgc ttgttttcct ttctctgcat ctatacaatc ccaaaaaaca
     5701 agtgattcat caaaagatgg aaaaagttga tgacatagct gcaaagtgat ttttgagtta
     5761 taacttagcc tgccacttcg ccccaacgtg atgcccaatt gctttatacc ttgctgcttc
     5821 aaataagtaa gaccttctgt aattgattgt tctcgatcaa taaagacaca gcttgcctgt
     5881 tttcccttga tttcttcaca aaaaactaga ggtccatatt tttgatatgc caataaatca
     5941 tctagtgtat tggcacgaga cgtaatgatc aatccatcga aagctttagc tgcaaattct
     6001 tcaagatacc ttcgctcttt ttctttctga tagcccgtcg gtaaaagtgt cactttgtaa
     6061 tcataatcaa acgctgcttc aatgatccca ctgatcaact gatcaaaata cggatgattg
     6121 gtataaggca gaatcactcc aatgcttttc gtttttccat aacttaactg tctggcattt
     6181 gcattaggga tataatcgac ttctttcatg accgcaagta tttctttcct tttttcctca
     6241 tctacatatg gatgtccatt gattacacgt gaaatagtag aaactgaata acctgtgagc
     6301 tttgcgatat ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa agattttctt
     6361 gtaaatagtc taccacagct ggaccgcatt caaaaaactg atacattttt ccttcatgcg
     6421 aaaaactgat ccgctgcccg ccccaatata tatcttttgt caaattttcg atttcattca
     6481 ttggtatttc ttttactata ttcctattca acccttgaaa actgtacaac gttaatacgg
     6541 atcccttgaa ctcgacaaac gcataaaaat aattgttcgt tgtgccatct gttatctcta
     6601 cataagtatt cattgcaagc cctccttttg atactttgag tatagtgtat gaaacgcgtc
     6661 tcatagcaag gagtttgttt tgccaaagaa aagttttatt cctctttcat tattaccaaa
     6721 gtctcttatt ttaaattgaa tacattataa tgatactgta aatatatctt tattattagt
     6781 gaatggatat ttacttttaa tagataaaat attataacta ttaaaaataa ctattttcat
     6841 tataattaca cacaaaaaag agcgtgagac aaaagtaaag aac
//
LOCUS       DACGDM010000118         6752 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.124, whole genome shotgun sequence.
ACCESSION   DACGDM010000118 DACGDM010000000
VERSION     DACGDM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.124"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            124..771
                     /locus_tag="IXR05_002560"
     CDS             124..771
                     /locus_tag="IXR05_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4261012.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            1164..3809
                     /locus_tag="IXR05_002561"
     CDS             1164..3809
                     /locus_tag="IXR05_002561"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAQ4261013.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4119..5432
                     /locus_tag="IXR05_002562"
     CDS             4119..5432
                     /locus_tag="IXR05_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAQ4261014.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5422..6075
                     /locus_tag="IXR05_002563"
     CDS             5422..6075
                     /locus_tag="IXR05_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4261015.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6130..6681
                     /gene="radC"
                     /locus_tag="IXR05_002564"
                     /pseudo
     CDS             6130..6681
                     /gene="radC"
                     /locus_tag="IXR05_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
BASE COUNT         2224 a         1144 c         1475 g         1909 t
ORIGIN      
        1 gatgcaagct tttgaacacc gttttatttg tctcacaccc ttttccttcc tacttgtaac
       61 cttgctcccg tgttagaaac atgttacact aaatatgtga aattattaac aaggagcgtc
      121 gttatgcgag aaaaaacaga tacactgcca aaagcaactg cgaaaagatt acctttatat
      181 ttacgctact tgaagatgct ggatgactca ggtataagta gaatcaaatc aaatgagttc
      241 agcgaaatca cccaaattcc ttctgcaacg atccgcagag acttctcgca attaggcgag
      301 ctaggcagaa gcggatatgg ctatgatgtc ccttttctta tcgatgtatt caataatatc
      361 cttaatacta aagaagaaaa acgaatcgca ttagtaggat atggaaatct tggcaaagca
      421 ttgaaacaca acaattttag aagaaatgaa aatctaaata tcgtgtgcgt ctttgataat
      481 gatccagcac tgatcaatcg agtaattgat ggagaaatga tctatccgat tgatcgtttc
      541 gcggagatag ccaaagcaaa aaatgtgaca gtagcaatct ctacggtacc aagtaaatat
      601 tcacaatctg ctattgatga aattgtcaaa ggaaatgtaa ccgctatact taattttgcg
      661 cctgacagag taactgtccc agcttatgtc aatgttcaat acattgattt gacaaccgag
      721 ttgcagacgc ttatttactt tgatgagaat tactcagaag ttttttctta ggaaaatttg
      781 agtaggctta ttgatcttgc gagaactcgt cgtaattctt tcaaaaattt tttagtacta
      841 aatgaagtgg ttttttcacg accacttgtt gactaaaaaa aaaaaccatt gtagaatgaa
      901 gcataacgct gaacaagagg agtaactggc acattcattc ttagagagag aactatctgc
      961 tgaaaggttc tcaatgacaa ccagtgaagg tagcttggga gtttctgtct tgaatggagt
     1021 agagatagac gagtcgtgat cgttaactca cttgagaggc aataatgatt gattattgca
     1081 atttaggtgg taccgcgtaa atcatacgtc ctagaatacg aaagtatttt aggacgtttt
     1141 ttagtttaaa ggaggaaaac agcatgacgg aagaaaataa cctatcaaca aaatataatc
     1201 cgcaagaagt tgaagctgga cgttatcagc attggttaga acaagatttg tttaaaccga
     1261 gcggagataa aaaagcaaaa ccttattcaa tcgtaatccc gcccccaaat gttactggaa
     1321 aacttcattt agggcatgct tgggatacga ccttgcaaga tatgctgatt cgtcaaaaga
     1381 gaatgcaagg atatgatact ttatggctgc ctggtatgga ccatgcagga atcgcgacac
     1441 aagcaaaagt agaagcgaag cttagagagc aagggatttc tcgttatgat ctaggtcgtg
     1501 aaaagttcat cgatcaagtg tgggaatgga aagaagagta tgcgagccac atccgcgaac
     1561 agtgggctaa aatgggctta tctttagatt acagtaggga acgttttaca ttagatgatg
     1621 gattatctga agcagtacgt aaagtttttg ttaccttata cgaaaaaggt ttgatttatc
     1681 gtggtgaata tatcatcaac tgggatcctc aagcacgaac agctctatct gatatcgaag
     1741 ttattcataa agatatcgaa ggcgcctttt atcatatgag ctatgaacta gcagatggat
     1801 caggcgtagt agaaattgcg acaacccgtc cagaaacgat gttgggagat acggcgattg
     1861 ctgttcatcc agaagacgag cgttatcaag cgctcatcgg caaaaaagtg attctacctt
     1921 tagtcaataa acaaatccca atcattgcag atgaatatgt agatatggaa ttcgggacag
     1981 gtgtagtaaa aatcactcca gcacatgatc caaacgactt tgaggtaggt aatcgtcatg
     2041 atcttccacg cgtaaatgtt atggatgatg atggtacgat gaatgaacta gcaggaaaat
     2101 atgctggaat ggaacgtttt gctgctcgta aagcaatcgt gcaagatctg aaagaaatcg
     2161 gtcgattgat taaaatcgat acgatgatcc acagtgtggg tcattccgag cggacaggtg
     2221 tcgttgttga acctcggctg tctactcaat ggtttgtaaa aatggcgccg ttagcgaaaa
     2281 aagccattga taaccaagaa acagatcaag cagtggaatt cttccctcca agattcaatc
     2341 aaacgttttt acgttggatg gaaaatgtcc atgattgggt aatctcacga caattatggt
     2401 ggggacatca aattcctgca tggtatcaca aagaaacagg tgaaatgtat gtagggatgg
     2461 aagcaccagc ggatagtgaa aactgggtac aagatcctga tgttttagac acttggttta
     2521 gttcagcttt gtggcctttc tcaacaatgg gctggccaga tacggaaagc gaagattata
     2581 agcgatactt ccctactagc actttagtaa ccggttatga catcattttc ttctgggtaa
     2641 gcagaatgat tttccaaagc ttggaattta ctggcgaacg tccatttgag aatgtcttga
     2701 ttcatggatt gattcgtgac gaacaagggc ggaagatgag taaatcatta ggtaatggaa
     2761 tcgatccgat ggaagtaatc gaaaagtatg gagcagatgc tctccgctgg ttcttatcga
     2821 atggttctgc accaggacaa gatgtccgct tcagctatga aaaaatggat gcttcttgga
     2881 actttatcaa caaaatctgg aatgcttcac gtttcgttat catgaatatc gaaggaatga
     2941 ccgtagaaga gatcgattta tctggagaaa aatcagtggc tgaccggtgg atccttactc
     3001 gtttgaatga aacgatcgaa cgagtaactg agctatttga tcgttttgaa tttggtgaag
     3061 caggtcgaca actgtataac tttatctggg atgatttttg tgactggtac atcgaaatga
     3121 gtaaagaagt actttatgga gatgatgctg tttcaaaaca aaccacccgt agcatcttag
     3181 tccatacact tgatcagatc ctacgtttat tgcatccaat catgccattc gttacagaag
     3241 aaatatggga acatattcct catcagggaa attctctagt agtggcagaa tatcctgttg
     3301 tacgtccaga gtttgatgat gaaacagctt ctaaagggat ggaagtattg aaagaattga
     3361 ttcgagccgt tcgaaatatt cgttcagaag tgaatacacc attgtctaaa ccaattacgt
     3421 tgctaattaa aacaaacgat gctaaaatcg atcaattttt agttgaaaat acaagctata
     3481 tcgaacgctt ctgtaatccc gaagagttga cgatatcaag tgagatcact gcgccagatc
     3541 tagcgatgtc agctgttctg acaggtgcag aaatcttctt gccgttagca ggattgatca
     3601 atattgaaga agaaatcaaa cgattagaaa aagaactgga aaagtggaca agcgaagtaa
     3661 aacgtgtcca aggaaaactt tctaatgaac gttttgtttc taacgcgccg gaagaagtag
     3721 tagaggcaga gcgtgcaaaa gaaaaagatt atttagagaa gcaaacggct gtcaaagaac
     3781 gaatcgaaag tttgcgtact attcaataag aatagaaaaa gagagtgtga aatcagctag
     3841 ctattactaa aagctagctg attgaacatc gttacaggaa agagtttgag cctcactctt
     3901 agcttcgatt cataaggaga tgtgacataa attttgtcgc atctcttttt tagtctactc
     3961 ttattatgta ggagaaggag ggaggtggat catgtatcaa gagtcaataa agtagttgat
     4021 aaaatcgttc ctctctctgt ttcttttctc tttgtcatac ttttattttt cttatgtgtt
     4081 ctatttgtta taataaaaga gaaatggggg aattgttgat gacgattgaa gaagcaatag
     4141 aatggatcca tagtcgatta ccatttggtt cacgtcctgg ccttgaccga gtcgaagctt
     4201 tattagaagt ggtagggcat ccagagagaa aagtaaaaac gatccatatc gctggaacaa
     4261 acggaaaagg ttctactgta gcttatttga gaagcctatt agaagaggct gggctgacag
     4321 taggtacatt tacttcacct tatatcgaaa cgttcaatga acggatcgca atcaatggca
     4381 aaagcattcc agacaatgat ttgatccagc ttgtaaaaaa atatcagcca ctgatcaaac
     4441 aacttgatca atttgaagca gtagctggta ttactgaatt cgagacatta acagcaatgg
     4501 catttgatta ttttttgatg aagaaagtgg acgtagcgat tatcgaagtt ggcttaggcg
     4561 gcttattgga ttctaccaat gtagctgtac caatgctgac gggaataaca acgattggac
     4621 ttgatcatac cgaaatactt ggagatacaa ttgaagaaat cgctgcacaa aaagctggaa
     4681 tcatcaaaca aggcgttcca gtagtaacag gaaatattgc cccagaagct tttactgtca
     4741 tccaacaaac agctaaagca aaaaatgcac cgctttatgt atacggggaa aattataaaa
     4801 taaactatct gcatcctgat gagatgtggg gagaagtatt tgaatttttt aatgaaatag
     4861 gaaagatccc tcaattaacc actccgcttt tagggcaaca tcaagctgaa aatgcaggag
     4921 tagccatcga attgtatttt gtttactgtc aattggaaaa gctgcctttc cgagaaaaag
     4981 atgttttgaa gggattgaag aaatctcgat ggccaggaag aatggagcgt ttgagtaacg
     5041 agccattagt tgttttagat ggtgcccata atacgcatgc aatgaaccgg cttgttgaga
     5101 atttgaaaaa agaattcaaa ggatatcaaa tcaacatttt gttttccgcc ttacgaacta
     5161 aaaatgttag agaaatgcta gaacgattgc agcaagtacc aaatgtccat atttatttga
     5221 cgacctttga acatccaaaa gccatcgaat taagtgaagt atcagattta gcaagtgaga
     5281 gagtatcaat cgtttcattg tggcaattcg gattagcaga tatattggaa aagatgacaa
     5341 atgaagacgt attagttgtg accggttcac tttatttcat ttcagaagtt cgccatttat
     5401 taatacaatt aggaggagat catgaagtat aatgcagtga tttttgacat ggatggtttg
     5461 ctgttcgaca cagagttagt gtattacgaa gccacacaag tagtagcaga caagatgggt
     5521 tttccttatg ataaagacct gtatttaaaa ttcttaggtg tttcagatga agaagtatgg
     5581 gcgaattatc atatgatttt ctcggaattt ggcaaaacaa gtgtacaaag attcatagat
     5641 gattcatacc aggaaacgct tgaacgtttt tcgcaaggag cggtacaaat gaagcccggt
     5701 gtgttggaac tcctctcttt tttagaagaa catcagattc ccaaagttgt cgcttccagt
     5761 aaccaacgag cagtcattga acttttattg aagaagaaca atctgtttga acgatttgag
     5821 acgattgttt ctgcagaaaa tgttcaacga gcaaaaccag acccagaaat tttcttgtta
     5881 gctaatcaga agctaggtac agcgaagaaa gaaacattga ttttagaaga ttcacaaaat
     5941 ggtattttag cagcttctgc ggctgagatc ccggtagtca tggtaccaga tctgcttcca
     6001 ccatcccaag aattgatcaa aaaaacagct ggggttgttt cttctttaca tgaaatccct
     6061 gcattgttaa aataaaaatc catctctttt cgtatcttat tttagataag atagaaagga
     6121 gatgtttttt tgggaaaacg attgatcaaa gaagtaccta ctagctcttt accaagggaa
     6181 cgtatggaaa tttatggcgc ggaagcttta tcggatcagg agcttttggc aatcttactg
     6241 cgtaccggtc aacaccctta tagtgtgatg tcgattgctg gaaatctgtt aaaaacgttt
     6301 ggaggactgg cctctttacg acaggctact ttgcatgagt tagaagagat tcgagggata
     6361 ggacgcgtga aagcaatcga aatcaaagcc ttgatcgaat taggtcgacg aattcagacg
     6421 gatcatgaaa gagcggctcc accggttcgt accagctacg aattggccca gcaattgatt
     6481 ctggaaatga aagatcacaa acaagaacat ttggtttgta tttatttgga cacgaagaat
     6541 caagtgatct taaaaaaaac agtgttcatc ggttcgctga atcagtcagt cgctcatcct
     6601 agagaaattt tccattatgc tgtacgttat tgtgcagcaa ggatcgtttt agcgcataat
     6661 catccttctg gtaatgtttt aaccatagta taataaataa tagtagttaa agtagtttaa
     6721 gaggagatat taaagggata ttttacttta aa
//
LOCUS       DACGDM010000119         6536 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.125, whole genome shotgun sequence.
ACCESSION   DACGDM010000119 DACGDM010000000
VERSION     DACGDM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.125"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            52..2727
                     /locus_tag="IXR05_002565"
     CDS             52..2727
                     /locus_tag="IXR05_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAQ4261016.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            2909..3148
                     /locus_tag="IXR05_002566"
     CDS             2909..3148
                     /locus_tag="IXR05_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261017.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3164..4537
                     /locus_tag="IXR05_002567"
     CDS             3164..4537
                     /locus_tag="IXR05_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261018.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4541..6175
                     /locus_tag="IXR05_002568"
     CDS             4541..6175
                     /locus_tag="IXR05_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261019.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTNLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6338..>6536
                     /locus_tag="IXR05_002569"
     CDS             6338..>6536
                     /locus_tag="IXR05_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261020.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2295 a         1062 c         1311 g         1868 t
ORIGIN      
        1 aggtaatgta gtcatacaaa taaaaatttt ttagaaagtg agtggtaatt aatgaaaatg
       61 aatcacactt caattcagaa gcatttacaa ctgttaaata cactggggat ttcttatgtt
      121 aatttgagaa ctttttctac attaaacaag aaaaccgttt ctcatatttt ttctactgca
      181 gattctcaag caattattaa ctatttagaa aaacagaaat tgtctgaagg tacagtaaac
      241 ataacttata atcctattaa acaagaggtg attacacaaa aaaagcattc tgtgagagac
      301 aatgatattg aaaaaattcg gtttgtattt attgatattg accctaaaag gaaagaggga
      361 agtgcaacag atagcgaaaa gaaaaaggca gaaaatgtta tggaacaagt agaacgttat
      421 ttgaaagaaa agagaataga atcatttgta aaagttgata gtgggaatgg ctaccatatt
      481 tttcttccca taaatgaaca accaaataat cacgagacga ttcttactat tcagaatttt
      541 cttcaattac ttcaccgaag atttggagta gaagatgaag ttgatattga tacttctgtt
      601 tataatcctt caagattatg caaattagtt ggtacaccag cggtcaaagg aaagtccaca
      661 aaagagcgtc cgcatcgttt atctagtttc ctttctattc ccgataacat agatagaagt
      721 aattgtttta aaattcttga acagatagtt gaagaaaatt ccatgatgtc aacctctaga
      781 gtaaaaagcc atccatcttt tagagaagtg ttacctttta ttcaagcaga ctataaacaa
      841 tggttagctc actatcctga attaacttat accataaaag agggcgatca taaaggagtt
      901 accttactta tatttgacga atgtccatta agaaaacaca cgaataattc taatggttct
      961 tgtttgtctg ttacggctga taataagatt cgatttcatt gtctgcatgc ttcggataaa
     1021 aataaagata ttcaagactt tgtaaaaaaa tatccgttgc caaaacctgt aaatccttct
     1081 gtagaatcat tagaatccaa tcaagaatat tattttgacc agtttaaact gaatcaagaa
     1141 ggagtatttt tggtgaaaga aggtcaagaa gaaaaagttg cttgtccgat gtttattaag
     1201 caaatacgca aaaatatcga acaaaaagtc attacacttg ttcttgccta ttatgtcgat
     1261 cattgttggg atgaaataga aatagaaggt ggatgtttac aaactaataa ttttaaacaa
     1321 ttagcaaaac atggcttaat cattaaagct agaagagaag ctgaagtcgt tgacttttta
     1381 cagattcaac gggagaatgc tccaatcttt tttgaacatg aatctcttgg ctggaaaaaa
     1441 gaaaatgaag caatgatttt tcagttacaa gattcttttg gacgtgaaat tccttctgta
     1501 ttaactaaaa actcatgcta ccaattaaca actaatggta cagaagcgga atttgacgca
     1561 ttggttcata agtatgtttt aggaacgaac ttagaacttg cttggtcgat tggtattgct
     1621 tctattgtgt taggctattt aaacgttacg aaggctaata cttttttgag tttactaatt
     1681 aacctacagg gcaagagcac aacgggtaaa accactacgt tacactttat tgcctcttta
     1741 tttggaaatc caactacggt tcttagaaat atgaatgcta ccaataaagc cattataaag
     1801 ctagcatcaa acaatcaggg aggtgttcca ctaatactag atgagttagg agcagcaact
     1861 caaaataact ttagctcgtt gatctatcaa ttagcttcag gagaagaaag gctaagatta
     1921 gattctaatt gtcagcttat gccacaagag actttttctg ttttgaccct tacctcttct
     1981 gaagagcgtt tggaaaatta tttcaatgag aaattaactg gtttgaaagt tcgatatatc
     2041 gaattttctg atatcaagtt tacaaaggat gcgaatcacg cagagaaagt taaaagtctt
     2101 tcttctaata cttttggttg gggtataaag ttatttcttt tgaaactctt tgaacaaggg
     2161 attacaaaaa ttgaagcaac ttttgtcgaa gctcaaaaaa aactatgggc tgttttacct
     2221 gaacattctt tgaagcaacg cattggtaat aatctagctt tgatttatag tggagccctc
     2281 ctaattcaag atatactggg ctatccttta cgattagagc atatacagac ggtgcttatt
     2341 aattcgtacg aacagttaat tgtagatact agtttaggaa gtgagcaaac ggtatttgac
     2401 cgagtgaaaa cattgttggt gatgaatagc cataaatttt taacaaacag tgacaacaaa
     2461 catacgccca gtacgatttg gggaaaagta tcaattcaaa aaaatgggga tattaaggta
     2521 aatatttttc ctatcccgtt tgaggacttg ttaaggcgag aatttcaagt aaaggatcta
     2581 acctatcttt ttaggcaatt gcttgattcg ggtaatatgt gtgcagaaaa agggagaaga
     2641 acgaaacgta ttcacatgaa tcgtcaagtt cttccaacat acgagattct attaccttct
     2701 tcactcaaat cgtattttcg attgtaattt agaataaacc aaagtatgaa agtgaggcac
     2761 catgttatgg aaatatttct tattgattta gcaaaacaac tgattactta tctgtatgat
     2821 agcgagcaaa cccaaacgga agtaaatgaa gcttgatcta tgcttcattt acttcattca
     2881 atcaaacatg aaagaaagga aaattctaat gactaaaaat aaaatgacac taaaagcaga
     2941 ggttcttctg tatattcaag aacatttttc aaatcaagcc ttttttacaa aaccaattta
     3001 cttggatttc gaaataagag gggtatctgc tggatctatc gggggtactc ttcaagcgtt
     3061 gaagaacgaa ggatatttag aaaatcactt tgtgcaacgt tcgttcaata gaagagtcgt
     3121 gaaaaaatgg tatttagttc attcatagag aggggaatca agcatgcgtg tggcttgtta
     3181 tgatcgaacg tctgtttatg aagaagcgaa aattagtaat gacgctcaat atgatgcagt
     3241 gaaagagtat gttttagaga aatatgaaca aattccccaa cgattttcag acaaaggaga
     3301 atcaggggaa aaagcggagc gtccagcttt tcgacagctt agagcttggg tttgtgcgtc
     3361 agaagaagag ggggtgatct atgtttggcg ttatgatcga ttggcacgtc aagccaaaat
     3421 agccttagaa tttattgagt tgtgccaaca acatcaggtt caagtgtatt cgatttctga
     3481 acctcttcct gcttctttct cacacgcgtc aacgaataaa ctatttgtgc aattattgtt
     3541 cacttttgca gaacaacaac gaaacgtcat tattgagaat gttcgtgccg gactttccta
     3601 taaaaagcaa caacggcaat atttgtcttc tgcggtacca tatgggtatc gtttagtgaa
     3661 tgggaaaatc caacaagaag tacacgaagc aaggattgtt cgctatattt ttcaacttta
     3721 tttgaccaaa aaatatggct acaaaaagct ttgtcaacga ttgacgcaac aaaagctttt
     3781 cttccgcgaa cgtccttttc agccctatca tatttatagt atcctaaaaa atccattgta
     3841 ctatggcgaa atcaaaggag gatctttggg gaagtatcta ggaacctttg aaccgattct
     3901 ctcgaaagca acctttttac aagcccaaga gattcgccaa tcaaggtgta cagctaaaaa
     3961 agatacgtat ctgtacttat tacgtcaaaa aattcggtgt cccttctgtg gtcgtcatct
     4021 gagttcgaag tatcaatgga atacaaagaa gacgaagacg cttcattatt atcattgtac
     4081 cgaccgaagc tgccaaggaa tttttcttcg ggcagaaagg gttgagtcag aagtattgga
     4141 aaagatacag gctttttttc aatacgaagg cgtctatcaa gccttgattg cccaattaac
     4201 gcaacaatta gccgaaaagc gaaaagatga aaaacgcaaa gtaatccaac aaaagaaaca
     4261 agaagcacaa tggattaagg catttgaaga gggcaattgt tcactggaag aactcaagca
     4321 acaactgcaa gctcttcaaa agccgatgtc tacttcttcg tttctttcac tccaacagtg
     4381 tgaagcaaaa gtgaaagaat ggcttcaact aaaagacctc tctagtcgac aattattatg
     4441 tgactatgtt tgtcggattg aggtaacaaa ggataaaaca gtttgtggga tttacttccg
     4501 acaactgaca caaaatattt tagaaaggaa cgaatgatct atggaaatga tacaaaccaa
     4561 acgagtcgca ttgtatattc gcgtgagtac acaagaacaa gctttagaag gacatagtat
     4621 tcaagcacaa gaacaaaatg gacgacagtt tgccgaacgg atgggctatg aagtggtaga
     4681 agtttatgcc gatgaaggaa tcagtgggaa atccacaaaa aatcggttcg cctatcaacg
     4741 aatgatgaac gatgctcgga accatcgttt tgatctacta gtgatttgga aattgacccg
     4801 tctcggacgc aatatgttag atgtcttaca aacagtcgag gaattattgc gatatgacgt
     4861 aggattacat tcgatctcgg aacaatttga cgtgaccact tcgacaggta aattgatgtt
     4921 acaactcctt gggagtttcg gtgaatttga acgcaaccaa attgcggaga atgttcaaat
     4981 gtcaatgcaa agcttagtga aagataaaaa gcgttatgca ggaggccgac gtttaggcta
     5041 tgtcagtggt attgacacga atggtcaaaa acaattggtc attgaaccag aagaggcgaa
     5101 aattgttcgt ctgatctatg caaaatattt aggcggagca gggtatcgag cgattgccaa
     5161 ttttttgaat cgtcaaggat atcaaacagt caaaaagaat gctttttcta ccacggcagt
     5221 caaagatatc ttacgcaata aaatttatgc agggtattta gaatatgcgc gctacatcaa
     5281 ttgggaaacc aaacgacgga aggggaagaa tccgagaccg attttagtga aaggaaccca
     5341 tgaaccgatt atttcggaag aagattatca aaaagtacaa gaacgccttg ctttagaagg
     5401 aaaacaaccc aaatggaacc atacaggtga aaatgtattg acaggcttgt tacgttgtcc
     5461 agaatgtggc gcaccgatgg cagcgagtaa tgtcacaaat accctaaagg atggcacaaa
     5521 gaaacggatt cgatattatt cttgttcagt ctttcggaat aaaggagcaa gtgtgtgtca
     5581 tgccaattcg attcgtgccg aacaagcgga aacatttgtc gccgaccgat taaaggagat
     5641 cgttcagcta ccagaagttc ttccccgatt ggtggcagcg ttaaatgaag aaatagtgcg
     5701 acaaagccaa ccattggaac aagaactcgt ggtgttactg gaacgaaagg aagaattgaa
     5761 gactaaaatt gaaaaatggg aagctgcttt ggaagatagt cctgaattgt ttccgatgtt
     5821 aaaagaccgc ttagacgaat tgactgaaaa acgacgacag ttgcacattc gagaaaatga
     5881 aatcttaggg atctttcaac aaggagagcc gattcaagtc aaagatgtcc aacggatatt
     5941 gactaatttg gatcgttttc ttgcccagag tgagaagaag caaatcaaag ccttgtatcg
     6001 tacctttata gagaaaataa cctttgatcc taaccataag gagatgttgg aaattacgat
     6061 gaaattcacg catgccgtgg tacaacaatt gaatgagcaa tatcaaatag ccgtatccaa
     6121 aacaaaggat acggctattt ttgtgttaaa aacacccttt acgttaacga tctagtctag
     6181 gttatatcaa acaacgttag aggggcgcta acgcttctct agcgatttga aatcgttaga
     6241 gaagtagtta gggaggtcct tatcataaat agggatattt attaatgaat atttgaaata
     6301 taattgtata taagaattaa aaagagtggg gatagatatg aaaaagatgg gtaagtgtat
     6361 tttatgtgaa aaatacactg aacttactaa agaacatgta ccacctaaaa aatcagggaa
     6421 tactggaggt aaaaagacca gaactggtaa tttagatgat ttccttaaga gcgattttac
     6481 aaaaggtgat tttccgaagg ggattaaaag gaaacctcaa ggaaatgttt attata
//
LOCUS       DACGDM010000120         6430 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.126, whole genome shotgun sequence.
ACCESSION   DACGDM010000120 DACGDM010000000
VERSION     DACGDM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.126"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..439
                     /locus_tag="IXR05_002570"
     CDS             <1..439
                     /locus_tag="IXR05_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261021.1"
                     /translation="LSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNKKMSLT
                     KNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSELVSYKQ
                     NHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            453..1142
                     /locus_tag="IXR05_002571"
     CDS             453..1142
                     /locus_tag="IXR05_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261022.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1267..3618
                     /locus_tag="IXR05_002572"
     CDS             1267..3618
                     /locus_tag="IXR05_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAQ4261023.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3698..4093
                     /locus_tag="IXR05_002573"
     CDS             3698..4093
                     /locus_tag="IXR05_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261024.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4418..5035
                     /locus_tag="IXR05_002574"
     CDS             4418..5035
                     /locus_tag="IXR05_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261025.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5076..5375
                     /locus_tag="IXR05_002575"
     CDS             5076..5375
                     /locus_tag="IXR05_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261026.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5409..5576
                     /locus_tag="IXR05_002576"
     CDS             5409..5576
                     /locus_tag="IXR05_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4261027.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5621..6226)
                     /locus_tag="IXR05_002577"
     CDS             complement(5621..6226)
                     /locus_tag="IXR05_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261028.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2214 a          891 c         1267 g         2058 t
ORIGIN      
        1 actaagtatt ttttcagtat ttacaatatt aattgggggc tattttcttt tgaatttaga
       61 ttctgttaat tcaaacgctc aaataaaaga tcaaagagta gctgaacata ataataaaaa
      121 aatgagtttg accaaaaata tctattctat gtcagatgaa gaattgtata aagaatttgg
      181 tgatttatcc ggggaacagt tagaagaaag tattccagga attagtgact cagataaaat
      241 tgttgtcttg tctgctggtg ggcaattaat gggagatggc aaatccgaat tagttagtta
      301 taaacaaaat cacagacagt ttattgatgt taatactgat tccaacgcta tttcgattaa
      361 ggatctaaaa gagcttttaa atagtaaaag aaatgaatta aagcagataa aagaaactaa
      421 ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa gatttttggt gtttctgttg
      481 ggctacttat gatgttaaca tttggaaatg cagtatatgc tgctgagaaa gaagttattt
      541 cagatccaga gcagtacgcc tcacgatact ttgctgattt tgaagaagaa gataaagtac
      601 ttgcattgcc agaaggtggt tttttaaaag gggaagctaa aattgtatct atggataatc
      661 cagatataat tcaaggttca tataattcag aaactgatcc tgcttcagtt tcagtgacag
      721 aagcaaaaaa aattgttgct gaaaaattca aaaatgatat tgaaactact ccaattatgc
      781 ctcgaggagc atttccaccc gatgttggta ctagcggaca ccttcttgta ctagcaggag
      841 gaggaagcta taaatcacag ccatttagtg gtgcgggatg gcgttttgga ggtatgggtg
      901 taaaaccagc tgatggtaca ggcaactttt tacgttggaa atcctacatt gacgatggaa
      961 gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg ttctattcaa ggaatggcat
     1021 tgtatgctcg tgaaggattc aaatactttg caccaaacgg gcctggttgg acaatgaata
     1081 taggtattta ttacacttat aatcctgttg caggtacgta ttatgttgtt caaaatattt
     1141 aataaaacag cacaaagaga tttctttgtg ctgttttatt atttttagtt gttgacaaac
     1201 actaaaatat aaaatataat caacacataa acgaacgtat gttcggcaag aaagcagggg
     1261 atttttatgg atgagatggt tttaagtact cagaaatggc taaacaagaa atacagtaat
     1321 gttacagggt ttgataaggt tccagaaaat gggcgaacag ggtggcctac aatctatgga
     1381 cttattgaag gactacaagt agaacttggt attactaatc tagtagctaa ttttggacct
     1441 accactgaaa aaatgtacga taatcaggtt actcctaaat ggggcaaaaa tctacctaaa
     1501 aatattgtat ttcttattca aggtgccttt tggtgtaagg ggattaatcc aggtggcttc
     1561 gatggggtat atactccata tttagatact gctgtaaaag agttgcagac tgatgcaggg
     1621 tttaatggaa gcgctgtaac tggagttttg gatgcgaaat gggccaaagc gttatttgat
     1681 atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa ttagaaaaat gcagcaatgg
     1741 ttaaatgtaa attatttaga atacacggga ataatgcctt gtgatggtat ttatcaaaga
     1801 aattcaaatc aagcattaat ttttgcatta caagctgaac taggatattc tcccagtgaa
     1861 gcaacagggt cttatggtaa tgggacaact agtaaaactt atcctgtgtc tgaaggtaac
     1921 tcgggaaact atgtaagaat aattcaatat ggattatatg ttaatggtta ttttgaagac
     1981 ggtacattcg atggtatttt cactaaatat atgggtttag aagtactggc attccgaaaa
     2041 tttatggtat tgcctgaata tactgaaata gcagatgttg ttgtaataaa aggactattg
     2101 tctagcgctg gagatattag aagatctgca gatggcgcag atacttctac gcaattaact
     2161 agatctcaaa tccaaacatt ggttgataat gatataaaaa tagttggtag atatcttact
     2221 ggtactgttg gaattggaaa agatgaacga aataagtatc taactacaga ggaattgaat
     2281 aatatttttt ctaaaaattt atctgtgttt cctatctatc aagatggagg tgcagcatta
     2341 gcttatttta cttatgatcg tggcttatca gatggtaaga aggctataga tgcagcaaaa
     2401 aatctaaata taccattaac aacagttatt tattttgctg ttgatctaga catgttaggg
     2461 gaagaaattc ttgcatatgc tggagaatat tttaaggggg tatctgctgt aatgtcatat
     2521 agcgggtatc aaacgggtgt ttacggaaca agaaatgttt gttctcaaat aatcaataac
     2581 gggtatgctt cgtttgcatt tgtttcagat atgtcgactg gttatagtgg gaatttaggt
     2641 tttcctatgc ctagacaatg gtcttttgat caatttgttg aatttaccat aggaagtggc
     2701 aacggagctg ttggtatcga tttaatcgct acatcgggta gagatagcgg atttaatgag
     2761 ttatcaaatg atactaataa tgataattac attgccaaat acaatcagaa ggttataaat
     2821 cagatggtac gtgcgtatca atatctatca caagctggtc ttgataatcc ttggaaccct
     2881 catttgacat tttatagata tgtaaattat tctggtttgt catgggacat catttcttct
     2941 cctgtaacag agcatgatag aaaaatttat gatgaatata ggaataaatt aactaatagc
     3001 gagggcctgt ataattattt tatagatcct aatactggtt caataatagg tttgcctcac
     3061 ttaattgtga cgttacaatc acagatgttt ctagccgaca caatcaatga tagtgtttct
     3121 gactttgcag gttggttagg agatttaatg acttgctggg gtgaagttaa gaaattagga
     3181 atacaaatgg agcaaggtgt atttgcatta gtaggtacgg ctgcaggtgg aacatttagt
     3241 ctagaagatt tataccaaga tgttgacgcg gtaaatgttt ataccttagc aaaaagaaat
     3301 tctgattcaa cagctttatc ggctttaaaa acgtactatt gtgataaggg tgctattgat
     3361 agatttaatc aatttgttaa gaacagattt ggttcttcag ataaaatcgc ttcagtaaca
     3421 aatagtttat tagaaaatga cgaaacagtt gatatcttag gtgtagggat aatttcattt
     3481 ttcattgata aaatagttaa taattcactt gggacagatt ttacttatct tgattttatt
     3541 ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa ttattcaatt tcaagaaaat
     3601 agaagtaaac ttaattaaga atcgtttact atttaaacag tgtccttttc ctttttaaat
     3661 atatacgata aaataagtat atgaattgta aaaggacatg atgattatgg aagaaataga
     3721 atggaataat ctgactcaaa ataataaaaa taattctgga tgtggaatta tctttatgtt
     3781 tgttatagtt ttgggaatag tagtactttt aataactgtc aagatagtag attactttgc
     3841 gaatactcct gaagaacaaa tacagagaaa acttcctgag tttgaaagag taccacctta
     3901 tgatccaaga gataattcat ttcaagtaaa aaaattaaaa gagtctccaa atgaaatgtg
     3961 gtttgaagtt acagttgaat caagcgactt caaagaaaaa aagaaagaat acaattatat
     4021 tgtaaaggca aaagtatcaa aaagatttat ttttaaccct aaattagaaa tatatagtgt
     4081 tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa agaagtcaaa ttctgatgtg
     4141 aaaaataaaa tataccatgg aagacataaa agaaaaactg gataactagt ttatttaatg
     4201 gcagaccgtt aaggcctgcc atttttatgt attttagcgg aataaatata atcatgcggg
     4261 agtgtaaact tactgtttca aaaagtatac tttttgacat gccttgattt tctttgttta
     4321 tgtatggcat aataaccaca taatacaatt tgaaacgttt ctgatttaat ctgattgttt
     4381 tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg agaaaatttt tttatatccg
     4441 ggtcagtagt tatgatcaat cgatcgaacg acaactgatt tccgcgaagg aattaggaat
     4501 ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa gattttaaac gccctgaata
     4561 tcaattaatg aaacggatgt ttcgaaaagg agatttactc tatctacaat cattagatag
     4621 actaggcaga aataaacaaa tgattttaga agaatggcga gaattaacta aggaaaagca
     4681 gattgatatt tctgtgttag acatgcctct gttagatact gctagttaca agcaactaga
     4741 tgggttagag acgcttatct ctgacttaat tctgcaatta ctcagctata tggccgaaga
     4801 cgagcggaaa cgaattaata gccggcaaag agaaggcgta gaagctgcga aacaaaaggg
     4861 tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa tttcctgcga tctattctga
     4921 ctggaaagca ggaaagataa ctgcagtcta tgctatggat caattgggca tgaaacgaaa
     4981 taccttttat cgacgggtga aagaatatga acataccttg caccactttt cttgatagat
     5041 ataacagcta ttagacggga agggagagtt tgaaaatgga cttaacgaat caaagggtcg
     5101 tttttactgg aacgctgcag caaatgacac gaacccaagc catcggtttg gttcactctt
     5161 taaacggcca ttgtcaatca agtgttactt caaaaacaaa tttcctggtt tgtggtcagt
     5221 attctaagtc gttgtttgat gattctctct atacaaaaaa ggaacaaacc gcgcgggact
     5281 tgattgcgtt aggtcatgag attaccattt tatcagaagt cgaattttat gcgttaatta
     5341 gtcaacagtt gaaagaatgg caacggtatt tataatcgtt agtaaaattt acaaggagga
     5401 aaatttttat gaagcgaaaa tcttatgatc gttggggcat tgaaataact agttttaatc
     5461 gaaatattgc ttttcacgtg gagtgtgact gtggggaatt agcaaaaagt gtttatcaaa
     5521 aaaattactt ttactgtcct aaatgccatc gccgatacgg ggtacatgga acatagaaac
     5581 gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt ctacaaatca ttcgctttct
     5641 ttattttata aatagttggt cgagagatcc cgttttcttt tgcaatctct gcaactggaa
     5701 tgccttgctt taacatgtcc accacggttt taaaaactaa gcgtttttgc ggatctgttg
     5761 agttaataga atactcgatt ggtcgtccct tatatcggcc ggctttttga gccaataata
     5821 ctccttgccg ctgacgttca cgaattttct cacgctcgtt ttgtgcaata taacttagca
     5881 gtgataaaaa catatcgaac atagcggtat ccaggagttc atttccagta ttaaaatcta
     5941 aaaactgtgc atctaatatt tttaacgcta cttttttctg tttcataaaa gcaactgtat
     6001 tttttatatc ttcataatct cttcctaaac gatctagtga tgtaacgatg acgcaatcac
     6061 cttcacggat ataatttagt aatttttgaa actcaggacg ctcagtatct ttaccactgg
     6121 ctttttcttg gaataattta tcaatgttaa gtccttccat cattgccaat tgtcgatcca
     6181 aattttgatc ttgtgaagat actcgaatat agccaatttt tcccataaaa aactcctttt
     6241 taaaagtgat ataatttaca tgtaaaattt acttgtagtt ttactgctat catagcattt
     6301 ttaaaaataa attttatgta gacttaaaat ttacttcatg gagggtttaa atggatgaaa
     6361 tcaaaagtaa caaaaaagca tttggcattt atttaggaga acctagtaca gaacaattaa
     6421 accaattttt
//
LOCUS       DACGDM010000121         6392 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.127, whole genome shotgun sequence.
ACCESSION   DACGDM010000121 DACGDM010000000
VERSION     DACGDM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.127"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..382
                     /locus_tag="IXR05_002578"
     CDS             <1..382
                     /locus_tag="IXR05_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HAQ4261029.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNLLTIPGAMSPTEIFKMFEMGADI
                     VKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKS
                     AVHQLNYERLMELAESFIDSLRVE"
     gene            complement(776..1783)
                     /locus_tag="IXR05_002579"
     CDS             complement(776..1783)
                     /locus_tag="IXR05_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4261030.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            2250..3656
                     /gene="lacG"
                     /locus_tag="IXR05_002580"
     CDS             2250..3656
                     /gene="lacG"
                     /locus_tag="IXR05_002580"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAQ4261031.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            3679..4002
                     /locus_tag="IXR05_002581"
     CDS             3679..4002
                     /locus_tag="IXR05_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4261032.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            4013..5695
                     /locus_tag="IXR05_002582"
     CDS             4013..5695
                     /locus_tag="IXR05_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4261033.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            5901..6392
                     /locus_tag="IXR05_002583"
                     /pseudo
     CDS             5901..6392
                     /locus_tag="IXR05_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         2034 a          981 c         1294 g         2083 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccttcta acaattcctg gggccatgtc gcccacagag atattcaaaa tgtttgagat
      121 gggtgctgat attgttaagg tgttccccgc caactgtctt ggaccggaat atttcaatca
      181 agtgcaagcc cctttaggaa gtttaccttt gatggctgta ggaggggtag atcagactaa
      241 tgcacaaaac tatttgaaca atggagcctc ttatgtagga attggttcaa aattttttga
      301 aaaaagtgct gttcaccaac taaattacga gaggctaatg gagttggctg aatcttttat
      361 agatagttta agagttgaat agaacccatt tgcggaatac aacttgtttt ataatatggc
      421 gttatctgta taaaacatag tatcacagtg aatgagattg aactggtaga ttgatttttc
      481 gaccagttct ttttgcgcgc tctgatgctt gatatattcc caacgagata aaaaatcccc
      541 caagatacta agatgaagcg tttatccaac ctcatactta gataaaaagg aggaaatgtt
      601 ctgaatgata aacaaaaatt agcgcgcaca atttggcgat gaaaaaatca tattgtattt
      661 acgtcaaaat atcaccatca aattatttat ggaaaacata ataggcataa acccgattgc
      721 tcggctacta tgtggacaca attatagttt taaagataag tttcaattac ttattttaca
      781 cctcttcttt agggataaaa cttttcctaa cggtcaattt tgcgccgatt aatgttttct
      841 ttgatatgtc ccgcgaatat accagttgat cacttaataa atctacacag gttttagcta
      901 tctcttcgat atctatctta aaagttgtaa gtggtggtgc aacgaatttt gcgatgtcgt
      961 catcattaat acttattact gccatatctt tagggatgtt aatacccaat tcatggcagc
     1021 cctgaagaac gccggcagct atagtgtcag atggtatgaa acatgcctcg ggcatatctt
     1081 catttaactc agctttcatt ttaagagtta attgataccc ttcgtcaaca gtaaatgatc
     1141 cttgggagaa aatatacttt tcattgagta gtccgctctt ttctaaatga tatcggaagg
     1201 catattcacg gctatcaatc tcttctttac ccgtttctag gttaaagaaa tttcctccaa
     1261 taaatccaat ttttgtgaaa ccttcattaa taaagtagtt aattgcttgt ctggccattt
     1321 cgtggaaatc aggttctaca gtatcgaagt gttcaggtaa tgggtttatt cctcggatta
     1381 cccccttata ccctttttga tttaagtagt acaattcctt ttttgtcaat tgtcctattg
     1441 cgataaatcc agtaatatcg tcaggaatgc tttttacacc atcgttttta gagatgaaaa
     1501 tcaaatctag attagctttt ttactataat ttttcaaatc atctttgaca tgttgatagt
     1561 agacatcctt ttttaactgt tcctctgaga tccaaaaaag aatggcaatc ttgtacagag
     1621 tagtcttaat ttttgtcaga tcatatccta aagatttggc tgtaacgatt attttgtttt
     1681 tagtatcaga tgtaatagag agtgactcat cacctttaaa aagtcttgat atagtagccg
     1741 ttgagtaacc agattttttt gcaatatctc taatagtaac cattgttcat cctcctaggg
     1801 atataataat ccttttcttt gttaaagtaa atcgaaactg ctcttttagt aacttaaatt
     1861 actttttcta gcaggaaacg aaactctgat atcagcagag agcctaatcc attaacagag
     1921 aagattgaat cgataatgga tagccacttg gagaatgatt agtaggtggg attgatttta
     1981 gtgggaatca gtccgttttc ttgtttcgtg taaattaaat tagtaaaaag ataaatttat
     2041 tttacaaaaa aacgtttaca aaacggtttt tgaatggtat atttatttta catcaaggga
     2101 tataagtgct tgtatatcgc aataaaatag atattcgagg tcggtttttc gttgtgtaaa
     2161 aaaatttact tatacatgtt aaaattatgc tgaggtgatt tatggattat tggcatattg
     2221 atcaaactaa ttttcaagga gagattaaaa tgaattataa aactttacca gaagacttta
     2281 ttatgggagg agctacggca gcttatcaag cagaaggctc tacaaaagaa ggtggaaaag
     2341 ggcaagtagc gtgggatact ttccttgtag aaaagggacg ctatactgct gatccagcta
     2401 gtgattttta taatcaatat ccagttgatg ctgaattatg caaaaaattt aaaattgata
     2461 gtattaggat gtctattgca tggagccgta tttttccaaa aggctatggg gaagtgaacc
     2521 aaacaggagt ggaatattat cataaggtat ttgctgaatt gaataagcat ggtattattc
     2581 cttttgtaac tcttcatcat tttgataccc ctaaagaact atttgataat ggagattttt
     2641 taaatcgaga aaatgttgaa catttcgtaa actatgcaca gttctgtttc gatgaatttt
     2701 ctgaggttca ttattggagt acatttaatg agatttatcc agttgcttca aatcaatatt
     2761 tgatcggatc gtttcctcca gaagttcaat ttgatataga gaagactgta acttgtttac
     2821 acaacatgat gtatgcgcac gcaaagacag taaacatttt taaagatggt ggatataaag
     2881 gggaaattgg tgttgttcac tcgctagaga caaaatatcc agcaagtgac aaagaagaag
     2941 ataagcatgc tgcgaaatta gatgatgcgt tatcaattaa gttcttatta gatgctactt
     3001 atttagggta ttactcagat gaaacaatgg cacatattaa tgagatttta gcagcaaatg
     3061 ggcaatctgc agatattgat tctaatgatt ttagagagat gaaaaaagca gcaaatcgaa
     3121 atgattttct tggtatcaat aactatggta gccattgggt taaagagtac aaaggagaaa
     3181 gcacacttca ctacaacact accggagaaa aaggtagcca agtctattgc attaaaggga
     3241 ttggcgagag aatcgtgcgt gaggatcttc cgaaaaccga ttgggattgg atcatttatc
     3301 caaaagggtt atatgattta cttgtacgaa tccaagacga atatccaaat tataataaaa
     3361 tatacattac tgaaaacggg ctagggtata aggataattt tgaagatggg attattctag
     3421 atgatgatcg aatcgattat ttacgccagc attttaatgc gatttccgat gctatcaaaa
     3481 tgggagttaa tgtaaagggg tatttcattt ggtcattaat ggatgttttc tcttgggtta
     3541 atggatacac taagcgttat ggactattct atgtagattt cgatacacaa aaaagatatc
     3601 cgaaagagtc tgcatattgg tataaatttg ttagcgaaac aaaaacgata atataaaaat
     3661 agttaggagg gcaaggaaat ggataggaaa gaattgcaat tattaggatt tgaaattgtt
     3721 gcttatgcag gagatgccag aagttcatta ttaacagtgt tgaaggaagt gagagaaggt
     3781 aattttgata atgttgaacg attattagcg gatgctgatg aaaatttaac cttagcgcat
     3841 aactcacaaa cgaaatgttt agctgaagaa gcgtcaggga acgaaatgga agtaggcgta
     3901 atttttattc atgggcaaga ccatttaatg acaacgattc tattaagaga acttatcaat
     3961 gattttgttg aattgtacaa agaaaaattt gctaaagcat aggagaagaa aaatgaatac
     4021 gattattaag caaattgaga agggaaaacc gttttttgaa aaaatctcac gtaatattta
     4081 tttaggggca attcgcgatg gctttttaac tgctatgcca gctattctat tttcaagtat
     4141 ttttattatg attgcggctg ttccagaagt atttaacgtg acgttaccag aggcattctc
     4201 gacgtggctt tggaaagttt atggttattc aatgggatta gttggtcttt tggttgttgc
     4261 tacaacagct cgatgtttag ctaattcaat gaaccgtcaa ttatctgatt caggtaagca
     4321 gattaatgaa gtttctgtta tgttagcgtc aatttgtggt tttgtaatga tggcagctga
     4381 tcaaattgat ggtgggatag ctactgatta tttagggaca aagggattat tagcagcttt
     4441 cgtttctgcg tttgttactg taaatgtgta taaattctgt gttaaaagag atttgacgat
     4501 ccgtatgcca aaagaagttc ccggaacaat cacacagatg tttagagata ttatcccctt
     4561 ttcaattgca gtatttattg ccgttttgat tgatacggga gttcgtcaat tttttggaac
     4621 atcatttgca gcaggtgtaa ttcaattatt gcagccatta tttagtgctg ctgatggata
     4681 tgtcggtatt gcaatcattt ggggagccat ggcaatgttc tggtttgttg gtgttcatgg
     4741 accatcgatt gttgaaccag cgattgctgc aattatttat gcgaacgtag aaactaactt
     4801 tgaattattt aaaaacggtg cacaagcctc aaaagtatta acagttggtc taggaaactt
     4861 tgttggaacg atgggtggta ctggagcgac actagttgtt ccttttctgt tcatgttgtt
     4921 cgctaaatca aaacaattga aagcagttgg taaagcttca tttattccag tttcgtttgc
     4981 ggtaaatgaa ccgttactat ttgctactcc tattattttg aatccgtact ttctaattcc
     5041 atttttatta gcaccaatcg ctaacgtatg gatattcaaa ctttttgtcg atgtcttggg
     5101 gatgaatagc tttatatccg tattgccttg ggcgacgccc gcaccgattg gcttggtttt
     5161 aggaaccggg tttagtgtgt tggcgattgt attagcggta gtattgattg ttgtcgatgc
     5221 gattatttat ttaccttttg ttaaggccta tgattctgaa ttagtagaac aagagttaaa
     5281 aaacattgct gcagaagaag taaaagaaga attggtcgaa gaaatccaag aagttggtgc
     5341 aactgcggca gttatagttg atgaagcaaa agcatcggtt ggtgaaggaa agcgcgtttt
     5401 agtactttgt gctggtgccg gaacgagtgc aatgttggct aatgcattag aagagggcgc
     5461 aaaagagaca ggtgttaatc tttctgctaa agcaggagct tatggttctc attatgatat
     5521 gatgaaaaat tttgatttaa tcgttctagc acctcaagtg aattcctatt tggatgatct
     5581 ccgtaaagat gcagacaaat tagggataaa agtaattgca actaaaggtg cagaatatat
     5641 caatttaaca cgtgatccta aaggagcagt tgattttgta ttgaagcaat tttagagctt
     5701 gcttagatta ataaagcgct agccaactta gctagcgttt tatcttaaac acaatggtaa
     5761 gcgctatctt tttttgctgt ttaaatttcg ggtattcttt ttgaggcgtc gattgtaaaa
     5821 ttaagctaga caactaaaaa gatcatttgt gctacactca aaatagttcc gaccaaagaa
     5881 ttaataagga gtgagtacaa atgacctaca cccatcttac aacagacgaa ctagtaatca
     5941 tagagtctta tttcaatatc gagaaacctg tcgctcttgt cgcacaaagt ttaaatcgct
     6001 ctagacaaac catttataat gtttattcgt ttctcaaaca aggaaaaaag tgctagatta
     6061 ttaccgtcaa tacaaacaaa ataaatctcg ttgtggacga cgttcaaccg ttttatctga
     6121 tgaacaatca acatatgttc aagaaaaggt agctcaaggg tggtcacccg atgtgattat
     6181 cggccgtggc gagtttccaa ttgattgttc tgttcgtaca ctctatcgga tgtttaaaaa
     6241 aggccttttt gacacacagt cgttacctat gaaggggaaa cgtaaaccga ataatcatca
     6301 agaaaagcgt ggaaaacagg cctttcgcag aacgattcat gaacggaaca gtctctatcc
     6361 acacctgact aaagaatttg gtcatctcga ag
//
LOCUS       DACGDM010000122         6303 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.128, whole genome shotgun sequence.
ACCESSION   DACGDM010000122 DACGDM010000000
VERSION     DACGDM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.128"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            334..714
                     /locus_tag="IXR05_002584"
     CDS             334..714
                     /locus_tag="IXR05_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAQ4261034.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            696..1610
                     /locus_tag="IXR05_002585"
     CDS             696..1610
                     /locus_tag="IXR05_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4261035.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            1855..2544
                     /locus_tag="IXR05_002586"
     CDS             1855..2544
                     /locus_tag="IXR05_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261036.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(2665..2751)
                     /locus_tag="IXR05_002587"
     CDS             complement(2665..2751)
                     /locus_tag="IXR05_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAQ4261037.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            3427..4377
                     /locus_tag="IXR05_002588"
     CDS             3427..4377
                     /locus_tag="IXR05_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAQ4261038.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            4398..4931
                     /locus_tag="IXR05_002589"
     CDS             4398..4931
                     /locus_tag="IXR05_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAQ4261039.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            5567..6100
                     /locus_tag="IXR05_002590"
     CDS             5567..6100
                     /locus_tag="IXR05_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261040.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
BASE COUNT         2323 a         1102 c         1174 g         1704 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagcttta ctcattgtac ctttttaggt acaatggtat tgcgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagcg aacaacatca aaatttggct
      361 agcgatcatt ctaaaaaata tacctatcga tccgagccaa aacaaatcag ttttcgagtg
      421 agcgaatccg aatttgcaaa gctgaagcag tcagctgaag ctttgcaaat gagtgtgccg
      481 gctttcgtga aagccaaggc acaaaacgcg cgtctggtga caccgaaagt ggcgccagac
      541 attgcccagg caatcgcgcg cgatttagcc aaagctggag ggaatatcaa tcaaattgcc
      601 aagtggtgca atacacacca acacgacgtt gctcctgatg atgctcaacg tttatccgaa
      661 aacctaaaaa tcatgcaaaa ggagctacaa aagatatggc aacagttaaa gtaagtcgaa
      721 ccacttcatg tagccgagca atcaattacg cagaaccacg agcaaccgtc aaaacaggaa
      781 taaactgtga cattgattat gccaaaagtg aaatgaaaca aatacgcacg ctttatggaa
      841 aagacgatcg tgtacaagca cacttattga ttcagtcctt tcgaccagga gaaattaccg
      901 ctgaaaaagc caatcaacta ggggcagagt atgcgaaaaa aatagcccct aaccaccaaa
      961 tcgcgattta cacacataca gacaaagacc atattcataa tcacattgtc attaactccg
     1021 ttaatcttga aactgggaaa aaatttcaag cccatgggca agcattttta aacaaatgtt
     1081 atgacctaaa tgacgagatt tgtcttgaac atgacttaac aatcacggaa cgaggaaaga
     1141 aaaccgaaaa acgaaccatg tctgaaatta aattaaaaga aaaaaatgaa ccggtttgga
     1201 aagacgaaat tcggtttgcg attgatcaaa caatgaaaaa caaaaaaact cgaacgtata
     1261 cccaattttg tgattcactt aaaacattcg gcattcattg cttgaatcgc ggaaaaaatt
     1321 ttacttacga attggtccac aaaaagaaaa aagtacgatc caacaaacta ggaaaggatt
     1381 acgaaaagga gacgatttta catgagctgg acagacgaga acgaacctac aatcaacaac
     1441 gaaccaacga gctacgaaga gctcgagcta gcattcgcga aactgcagaa gaagtacgaa
     1501 gagaacaacg aacttttacg cctgaacaat cggaaattag accgactcga agaaaccatg
     1561 aacaacacgt tgaacgagga acagaccacc aacaagaatt atcgctctaa aacgttaaaa
     1621 gacatcgaaa acgaaataaa gagacaacgt gcctttcttg cgccttatac ccaagaaagg
     1681 atacaaacta cgatggattc acaagtcaaa aaactccacc aagcgctatt agaccagcga
     1741 aaccaagaac aaaaaaaggc tttaattcaa cgatcgatgg atattcttgc ccccttatgt
     1801 tgcttagtac taacattatt agccttttgg ttggtatggg gagaataaac agacatggca
     1861 ttctatttac cctatctact catttctgcc agtattttag gaattatttg gcttagctat
     1921 aaggcttatc aaacaagata ttcattaaaa ggctctaaaa ttcgatttaa gcgattttta
     1981 ttggtcgggg ttatatttgc cttatcaatc gttttaagtg gtttattcgg cgttttagag
     2041 ggtaataaac gtgtttcaag aagcatttta ttaggggata tcactcaaaa gtatgaagca
     2101 gcatgtgata aaaagaaaaa agagcaagca ttagcacaaa aaatggagga atttaccgct
     2161 tgttatgagg acatgaacaa tatttttgtg gatcaagaga aacgtttaac agataaaaac
     2221 atgaaaaaac tcactcgttt ttatcaaaac ttaccagaaa aacagcaaaa agaggtacaa
     2281 gaaaaatatg agcaagtaaa aaaagacgtg caatatttta aagatacgca gacagaagaa
     2341 gcttgttgta acttatttag cgatacaatc cctttttcaa ccagtgaaca agaacgaaaa
     2401 gaacggcaac aatcggtcac atacgaacgt tatgaaacac tgcttcagca agcaacaaac
     2461 atacaaaatc caacgaaaaa agaaacggca ttaaattatc tagaaagtgt caaggaatgg
     2521 ttggatcagc aacaacaaaa ttgaatttga ttagcaatca tgttaaactg aacctgcaaa
     2581 tgatcaaaca ttagatacac gaaagcccca gagaggtcgg attctctggg gctttttttc
     2641 aggttgatgt cgcctttatt gattttactt cttgtttcgg ttattcaacc aataactgaa
     2701 taaagagaca caaacttcta caagaagggg gcaaatgaac cgttcaaaca ttagatacac
     2761 ctccttccag tcgcaagact gtcggatagg cgacaagtta ttatacctta caaaataaaa
     2821 tctgtgtggt gtttttaagt atcccttatt ttcgggttgt tagggcttgc cctgaccgcc
     2881 tgtaaggcgc tttaagaaca agataaggtt ttttacccaa gactgtctta aaacgactta
     2941 gacgagctat cagaggcttc ccccacctcc gttactgact tgtttttagc aaaggagcct
     3001 ttaggcgact gcgcagtaca atgtgagagc atagcgatca cactttttta gcgaccgtag
     3061 ggagcaaggt tttgaattgg cagttttgaa aaatgcgcga acctgttggt agaaaaaaga
     3121 agtggttttt aggcgggaaa ttttgtcacc ctcttttata atctcttttt aaaccttttt
     3181 ttaaacctct ttaccgtcgg ctgtgtcctt actccttcaa tggatacagc gttttataaa
     3241 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     3301 tttaaactac attttgtctg cttttaaact ctttttttgc actcacgtat gttataatat
     3361 gcattatcac agacaaaacg ttgtttataa cgtctgtatc cattgaagga gtaaggagga
     3421 atatctttgg caaatgaaat cgtgaaatac catcatgaat taaataccat tccgttgcgg
     3481 aaatttacac cagttgaaat gaatctattt ttctctattg tgtctagaat gcgcgaaaaa
     3541 ggcgataaaa cagtccgtct tacttttgac caactaaaag atttaagtaa ttataaagca
     3601 actgctaata atcgtttcat taatgattta gaaatgactt atgataaatt aatggattta
     3661 cgttttggta aaagaagtgc taatgggctc gatatagata gattcgttat gtttagtgag
     3721 tttaaaatac gtggaactgc taaagatcca tatgtagaca tacaagttta cgaaaaagct
     3781 ttacctttac taaacaattt agatgagtgg gttcgctatt cactccaaca atttaacgaa
     3841 ttacaaagta gctatgcaaa gactatgttt cgattactaa aacaatatcg aactaaaggt
     3901 tttgcttatt tttctaaaga ggattttcat gaactattag atattccaaa aagttactgg
     3961 aacaaccaag caaacgttga taatcgtgtt ataaagccta tacgacagga attaaccgca
     4021 atcttcaaag gattatcaat caaaaagaaa tacggaaaag ggcgaggaaa acctgtcgtt
     4081 ggctatcaat ttacgtttaa accagaaatc aaaaaagcag atgattttaa taaacatgca
     4141 ccaaccaaag aagaacaaaa taaagcattg gctttagctg ataaacaaaa agaatacgaa
     4201 gaacctgcta caacaattaa cgaaaaaatc aaacagaaga aacgagaact tgaactcctc
     4261 caacaaatca aacaactaga aaaagagaaa gaagctcttg aaaaacaaac agagtccgca
     4321 ctttcgaaaa aagagaaaaa aagtttatta tctgatttag ataatttatt ccagtagcaa
     4381 cctaggaggc aaccagtatg caaccacaag aaacctttac aataaaggaa ttgtcagaac
     4441 tttttaagat gagtaggcaa gcaatatcga aacatatcca aaaattagat tcttccatga
     4501 tagctaaaaa tgagcgtggt tataaggttg tattgcgttc tggagtattg caacttgctc
     4561 gcaacttagg caaccaaatg ttgctagata ggttgcacga gtacgaacaa gacaacgata
     4621 aaaatgttaa tataccaagc aaaaacgtgg ttacaaacaa gttgctagat cagttgcgtg
     4681 aagaaaatga atttttacga gaacaacttg ccctcagaga gcaaaataat tctcatatac
     4741 aaaaactact cgaccagcaa caacaactca ccctacaagc caacaaacaa atcgaaaaac
     4801 tgcaagaaaa actacagttg acttatacag aagaagctcc agagaatgac tcaacgactc
     4861 tttctgaagc aacagaaaca atagacaaac aaattgatac tgaaaaaaaa tggtggcaac
     4921 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     4981 tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa gggaataaac
     5041 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     5101 aagaaacaga taaataataa aaaagactgc tctttcgagc agccagttaa aaaataatga
     5161 gtgtttattc ttgaaaaagc aacgcgctta tgaagcgcta ccaaaaattt atcatatttt
     5221 attaaaaata acaacccagt aaaaaatgac tggtaaaaat tcacaaagaa acggaaagaa
     5281 gcaaccgcag aaaatcaagc ttaaaaagag cttttgacct agaccaatcg aaaatcacaa
     5341 agtgagcgcc tgtatctatt gctacaggcg ctacttggca tagtgtacat tatgtcaaca
     5401 agaatttaat ataacatatt ttcctaatgc attctaacta taccacatta tcaaaaatat
     5461 aaattatctt tactaaataa aatattgaca agcctatacc ttttgtttta tgattttcac
     5521 aaagaaaacg ttttctatat atttttctgt atcaggagga aattctatga aaaaatttac
     5581 tttaggggta gctttgttaa ctattggggc agttgtttta ccgtcaacta ctatagttta
     5641 tgcttcagaa aattcccaag tggtatcatt aaacgaaaac aatgctactg aaaatgtagt
     5701 tattgagtac actgaagatg gtatggtcgt aactaaatat gaggatggtt atagtgcgga
     5761 agattttgca aattcttcag atatcatgac aagagctgca gttgcaagat ggggcaaaaa
     5821 ggaatataca aatattgctg taaccactgg agtagctgct aatgctatta atgctgcctt
     5881 ttgggcagga gggaaagcta gcacttctat gtttggtatc ccaggttggg caattggtgc
     5941 tttgttaaca ggtgcaagtt ggactaaaaa aggtgcttct ccagggaatg cagttgcaaa
     6001 agaatgggac aaaaatggta atggctggat tggattttat taccaaaggg gatatgatgc
     6061 agctggaaga gttgtagcta ctagatattc aacgttataa gttaaggagt gatgtttttg
     6121 atatctaaat cattaaaatc attaaaaaca tttactaaaa agaatccgca aatagctact
     6181 attcgtattt ttatatttgc tatagctgtt gctataattg ttaatatgct aagcggaggg
     6241 caattataca aatctggttt atttttagtg ttaatcttag ttgtcttaga cataataaag
     6301 tct
//
LOCUS       DACGDM010000123         6203 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.129, whole genome shotgun sequence.
ACCESSION   DACGDM010000123 DACGDM010000000
VERSION     DACGDM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.129"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(99..1235)
                     /locus_tag="IXR05_002591"
     CDS             complement(99..1235)
                     /locus_tag="IXR05_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4261041.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVNFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(1351..2265)
                     /locus_tag="IXR05_002592"
     CDS             complement(1351..2265)
                     /locus_tag="IXR05_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAQ4261042.1"
                     /translation="MKKIVFGLLFLGLVLSGCSTSPNSASTKENTVSSTSEYETKKLT
                     SSDVHKIKVGDDLTQVYQTLGSPLRKWTNDFVYKELDNAITRDELIVSISKDAQGDYY
                     KEHSELIEHGNSAKDIKKLEMLQYTYSTDSDDETMLIWVSPKTEQVVYYNQRTFLDKD
                     GKSKDSSSTTTTTTTSSSEPQTASVAHSIGEAVPFTSENGNSINVTVQSVSKDYGDDF
                     YKPEGLFYAKVDFLVENTGTTPFDASSSYLEFYDSSDIKSDLASRDYFSETIQPGKSA
                     QGTAYFEVKNDGTTFEVFFADTSWKGSY"
     gene            complement(2356..2784)
                     /locus_tag="IXR05_002593"
     CDS             complement(2356..2784)
                     /locus_tag="IXR05_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4261043.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKRIEELKNLYGLPESAYRFLI"
     gene            complement(2789..3163)
                     /locus_tag="IXR05_002594"
     CDS             complement(2789..3163)
                     /locus_tag="IXR05_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261044.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
     gene            3449..3634
                     /locus_tag="IXR05_002595"
     CDS             3449..3634
                     /locus_tag="IXR05_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261045.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            3646..3894
                     /locus_tag="IXR05_002596"
     CDS             3646..3894
                     /locus_tag="IXR05_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261046.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            3925..4104
                     /locus_tag="IXR05_002597"
     CDS             3925..4104
                     /locus_tag="IXR05_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261047.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(4147..4617)
                     /locus_tag="IXR05_002598"
     CDS             complement(4147..4617)
                     /locus_tag="IXR05_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261048.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            4704..5402
                     /locus_tag="IXR05_002599"
     CDS             4704..5402
                     /locus_tag="IXR05_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAQ4261049.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            5580..5921
                     /locus_tag="IXR05_002600"
     CDS             5580..5921
                     /locus_tag="IXR05_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261050.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            5914..>6203
                     /locus_tag="IXR05_002601"
     CDS             5914..>6203
                     /locus_tag="IXR05_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4261051.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTET"
BASE COUNT         2021 a          972 c         1087 g         2123 t
ORIGIN      
        1 attcaagggt tctttttttg ttctctgttt ttttatatta acgatttcta tttgggacat
       61 ttttgattaa taaaaagggg caaaaaaggg gcaacaagtt acagtttttc tatatcttct
      121 ttcaattttt cttttactcc ctttgtcaca tgcaaataaa tcttttcagt gatatcacta
      181 ttttcgtgcc caacgcgatc ctgaatagca tacagaggag ttcctagttc cgctaatttt
      241 gaaatatggg tatgtctaaa aatatgtgaa ctaagttttt tatcaatctt catgtcagct
      301 ttatgatttc tcaaataggt gttaattgct gttagttgga aaggagttcc tttcgttgtt
      361 tgaaatagaa attgaccatt cggatttaat tctagaagct cattgtaaat agctatcgct
      421 ttttttggta aatcaatttc tcgcattcca gcagcagttt ttgtagaatc agattttttc
      481 atatcagcta ttgaacgttc tctatacatc atcgtcccat ttataactac tgatgcatta
      541 ttattggtaa tgtgtacatc gtctttactt aatgcgattg cttctccagg cctcattcca
      601 gtcaaatata gccactggaa aaggagagaa tatcttttat tgtgtgaagt tgtgaaattt
      661 actagtcttt tatattcatc atcttctaaa aacttatctt taatttttat cgtttttgac
      721 tctcgtttat aatcaataac tacttcgttg ataggatttt tttctacata gccttttttc
      781 atagcgtatg aaaaaagaag attcaatttg gatttaatta cactgacgta cttatttgac
      841 aagtcatctt tatatatcat atcttcaaaa atattattta aatctactgt attaatacca
      901 gaaacgatgt aagtctcagg tatctttttc tttatagtgt ttaagatatt attcgtagga
      961 taatatgtag actccttaac ttgtcttttg taaataacta accattcttc gacaagctca
     1021 tgaaatgtta gatcaggctt ctgaagtgtt ttttcgttta attttatatc aattttttta
     1081 tttaactcta gcaatgccac tttctgagtt tctcgagatt tatttttata agtaatgctc
     1141 actttttttc tttttctagt ttttggatca atatatcgct cattatattt atatactttt
     1201 tttccgtttt tatcagtttt ggtttcaatc cacattgttt tcatctccta tttgttgcta
     1261 taataggaat ggataagtaa gccaattata gcaggtttat ttttcatcac gtccacaaac
     1321 tttggcgagg gagggggcgt gtttttttgt ttagtagcta cctttccatg aagtatctgc
     1381 gaagaacact tcaaatgttg ttccatcatt tttcacttca aaatatgctg ttccttgtgc
     1441 ggatttaccc ggttggatgg tttccgaaaa gtaatctcta ctagctaaat cagatttaat
     1501 atctgatgaa tcataaaatt ctaaataact tgaacttgca tcaaaaggtg tagtccctgt
     1561 gttttctaca agaaaatcta cctttgcgta aaataggcct tctggtttat agaaatcatc
     1621 accgtaatct tttgatacag actggacagt tacgttaata gagttaccat tttcagaagt
     1681 aaaaggaact gcttctccta tactatgtgc aactgatgcc gtctggggtt ctgaagacga
     1741 agttgtagtt gtagttgtag tagagcttga atctttggat tttccatctt tatctaagaa
     1801 agttcgttga ttataatata caacctgttc agtttttgga ctaacccaaa ttaacattgt
     1861 ttcatcatca gaatcagttg aataagtata ttggagcatc tctaattttt ttatatcttt
     1921 tgcactattt ccatgttcaa ttaattcaga gtgctcttta taataatctc cttgtgcatc
     1981 ctttgaaata gatacaatta attcatcccg tgtgatagca ttgtctaatt ctttgtaaac
     2041 aaaatcattt gtccatttac gtaacggtga accaagtgtc tgataaactt gagttaaatc
     2101 atcaccaact tttattttat gaacgtctga tgaagttagt ttttttgttt catattcaga
     2161 tgttgatgaa acagtatttt ctttagtgct agcagaatta ggactagtgg agcatccgct
     2221 taataccaag cctaaaaaaa gcaacccaaa aacaattttt ttcattttta attcctcact
     2281 tctatgatat gatttttttg taggatctta gaaataaggt ttttagtccg tgttgcagca
     2341 cggacttttt ttacattata taagaaagcg ataagcgctt tctggaagtc cgtaaagatt
     2401 ctttaattcc tcaattcgtt taggatattg atcattgtct tctttgtata gagaaacaat
     2461 gagattagca gcaaagcaat tagcttcgct ttcagatttg cttctagatg ttcttgttga
     2521 tacatagtaa ctggataagc cacgatgaaa aatagcgtga cctaattcgt gagcgcaaat
     2581 gtagaatctt tcctcagagt ctctcagttc atcatttaag aagattattg cacgacctct
     2641 aatttcttga aactgtcctt tgggattctc gataaaagga acgtattgaa ttttaatgcc
     2701 catcttttca caaatataaa aaggattagc ggactggtat ttccgcttca actcctcgac
     2761 taaattaatc gtatccatct ccataagctc acatcttttt gcctttttct ttgtcttctt
     2821 tcacaatatc ccagaaggtt ccaataagga tatcttttac gcgttggacc tgttcaggcg
     2881 tcagtgtttc tccgccataa gacatattga catttgaatc tagtaattta tcaagttcaa
     2941 ctacttcatc ttttgttgcc cagtcaggaa cttggtttct accgagtaaa taatcagtag
     3001 ttacattaaa ataatctgct acaagttgta gtcttttagt actaggagtt ctatttttcc
     3061 attgataaat cgtgttttta ggtatattta attcttcttc caattgagtt atacttatgc
     3121 ctcttttatg agctaattcc tttattctat ctagtaaatt cattttcgca cctcacaagc
     3181 tacgaaaaca ctaataaaaa aattagttaa aggtgttgac aactaataaa agtgttagta
     3241 tactgttttc gtaagctaaa atattagcta aaaagacttg ataactaata aacacttcac
     3301 ggtcggcaaa ctctgaaatg taaattacta ggcatttctg tgtcttattt agctatgtct
     3361 atatactaat aaaaatatta gttattgtca acgaatatta gctaattttt tagcttacag
     3421 attatttttt tagaaaggag ctatttttat gtctgagaat ttagacttaa aaattcgagc
     3481 ggagatgaga aaaagaagaa tgactttcaa agaactagct gcgcttatcg gtatttcagg
     3541 agcttattta tcagatattc taaacggcaa tcgtgatgga aagaaagcac aacagcatat
     3601 cgaaacagtg aaaaaaatat tggacatccg ataggggggt aggcgatgac aaaactaaaa
     3661 aaacaagatt ttgtaaaaaa atacaattat tctccatcta cttatcaacg tcgaatgtcg
     3721 gaactaaaaa atacagcaat tttctcagcg gcgtatgaac gggtcacagg acaagaagtt
     3781 tggatcaata cagaattata cgataaattt ttgtctttca aatcctataa caggttacgc
     3841 acaagaaagg taacacctaa agaatttatc gagaagcatt tagttgattt ataaaaaaca
     3901 gaacattttg agaggtgaag gttaatgggt aaattcaaca gagcattggt attcagcgca
     3961 ccgctaatca tctacgcttt aggactttgg ggaagcaggc aagcgttgat aggaacgatt
     4021 gtttacatgg tttggatttt tatggggctt gatgaagctg aagctgagta cagagcgaaa
     4081 aagccaaccg agggggctga ctaaaaatga atagaaaaga gaaactagaa tgtatattac
     4141 tattactcag tttaattctt tcactaattt ctctattggg aagtttgtat ttttgatatc
     4201 aacaattttg tggatttggg ttctatttag agtaaatatc atttttgttt ggtgattaag
     4261 gagtttatta aaattaattt tccctacttc aaatgcaagg taacaagata tagcactttt
     4321 aggaggaata tttagcggta cagcttcaga gtatattcta ttatcatcga ctgatcctcc
     4381 tttagcaatt aatttcttaa atggagtagc tgaccatctg cggtttaagt tagcggatga
     4441 aagttctaaa ttaactaaca tagctggttc tgttgaatag ttagaaatga ttacttttgt
     4501 ataaatcata tctgcagcga agtaagaagc attaagttca acttctagtt gagggcgcat
     4561 tccttttatt tttatccctg ttaaaaacgt actcaatata aaacttatta ttgacatcca
     4621 ttgaaaaatt gttaagtgaa aaaaattcaa aataaacacc accagttttt aactaaatta
     4681 taccaaaaag gagagaagaa ataatgcaag aattagtaat tttgaaaaat aaagaagctg
     4741 tgactacgag cttacaagtg gcagaaagct tcgagaaaaa acatcaacat gttttaagag
     4801 atattgatgc actaaaaaaa gatgtgtcca attttggaca gatgtttgta gaaggtaatg
     4861 aaccagattc atatggcaga aatcgacgag ttttcttcat tagtagagat ggatttttct
     4921 tgctggctat ggggtttaca ggaaagaaag ctatctactt caaacaaaaa tacattgaag
     4981 cattcaacga aatggaagat gttattcgca agaatactgt tcctcaaaca attgaagata
     5041 tgatgatcta tcaattagaa gaaatgaaag atgttaaaaa agatgtttcc atgcttaaag
     5101 atactatgcg aattagcgga caacaagagt ttgaaattaa gcaaaaagga aatatgaaag
     5161 ttatgggagt tctaggggga aaagaaagcc gagcttatga agaaatcagc aaaaaagtat
     5221 tctcaaaatt ttggtctgaa tttaaacgta ccttttcaat cccaagatat ggcgagttac
     5281 ctcgtaagag attcgatgat gctgtttcat ttattgaaat gtggttgcca gaaactgcga
     5341 tccgtatgga aattgatcaa ctgaacagac aacagagact ttttggtgat gacaatgaat
     5401 agagctgaag cgctaagaat agggacggca attgctaatt gctggtggaa atactataaa
     5461 ccaatcatcc taagccaaca acatattgac aagcaaaaag catggcaaca aataaaaaag
     5521 tgactccgcc ggcaagcaaa gagtcacaaa gaaaacacat cataaggaga ttttagcata
     5581 tggaaaaaga actttccact ctagatcaat atttgattga tcctgattgg ggcaagccga
     5641 aaattgagga aacaagtggt cgaaaaatca gacgaaatct tttgacgaat gaagaactag
     5701 cttgggatca agatgattta ggcaaccatg taactatttg ggatcatgtt tatcttatcc
     5761 atctatcgaa gcattcgaat aaacctgaat atatttacgt catcgaagat ggcttgattg
     5821 atgcgctaga agagtacgac agagataact tgattgatat ctcttattac ggaccaggta
     5881 agaaatacat tgctgaaatg gaggcagaat ttgatgagtg aaatcaaagg gacaacgaac
     5941 tttgaaaaac tttttagtcg taagttaaat aaaattctca agaaaaaagg aaattttgat
     6001 tatttatctt gggctcacgc gtgggagatt atgaaaaaga atgatccaca ggcaacggta
     6061 actattaatg agtacaaaca ctacagggtt gtttctggaa ctcatcaaga ctttcttgtt
     6121 gaggaatata aaccttttct tatggatgaa actgggactt atgtatctgt ctcagtaacg
     6181 gttaaaggac acacggaaac cga
//
LOCUS       DACGDM010000124         6173 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.130, whole genome shotgun sequence.
ACCESSION   DACGDM010000124 DACGDM010000000
VERSION     DACGDM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.130"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            725..811
                     /locus_tag="IXR05_002602"
     CDS             725..811
                     /locus_tag="IXR05_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAQ4261052.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="IXR05_002603"
     CDS             complement(932..1621)
                     /locus_tag="IXR05_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261053.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="IXR05_002604"
     CDS             complement(1628..1906)
                     /locus_tag="IXR05_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261054.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="IXR05_002605"
     CDS             complement(1866..2780)
                     /locus_tag="IXR05_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4261055.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="IXR05_002606"
     CDS             complement(2762..3142)
                     /locus_tag="IXR05_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAQ4261056.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="IXR05_002607"
     CDS             complement(3592..3879)
                     /locus_tag="IXR05_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4261057.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="IXR05_002608"
     CDS             complement(3899..4123)
                     /locus_tag="IXR05_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAQ4261058.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4763..5296)
                     /locus_tag="IXR05_002609"
     CDS             complement(4763..5296)
                     /locus_tag="IXR05_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAQ4261059.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="IXR05_002610"
     CDS             complement(5317..6159)
                     /locus_tag="IXR05_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAQ4261060.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DACGDM010000125         6002 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.132, whole genome shotgun sequence.
ACCESSION   DACGDM010000125 DACGDM010000000
VERSION     DACGDM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.132"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..395
                     /locus_tag="IXR05_002611"
     CDS             <1..395
                     /locus_tag="IXR05_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261061.1"
                     /translation="ISLKDESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQE
                     YYFYKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKI
                     GVINFKNKYQIKGIKLSHETIKKLRIGG"
     gene            398..1228
                     /locus_tag="IXR05_002612"
     CDS             398..1228
                     /locus_tag="IXR05_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4261062.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKMQRNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            1244..2095
                     /locus_tag="IXR05_002613"
     CDS             1244..2095
                     /locus_tag="IXR05_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4261063.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            2092..2451
                     /locus_tag="IXR05_002614"
     CDS             2092..2451
                     /locus_tag="IXR05_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAQ4261064.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCSQYRV
                     PLILAKKYRNTFKEERF"
     gene            2466..2627
                     /locus_tag="IXR05_002615"
                     /pseudo
     CDS             2466..2627
                     /locus_tag="IXR05_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            2624..2929
                     /locus_tag="IXR05_002616"
     CDS             2624..2929
                     /locus_tag="IXR05_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261065.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWAEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            2929..3240
                     /locus_tag="IXR05_002617"
     CDS             2929..3240
                     /locus_tag="IXR05_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261066.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGANIQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     E"
     gene            3407..3823
                     /locus_tag="IXR05_002618"
     CDS             3407..3823
                     /locus_tag="IXR05_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HAQ4261067.1"
                     /translation="MIPRFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIELMQSTGLKDKNGIEIFEWDIVSVSVRNGFDYLDNKVCVVKNSIGHSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIWENSELLEEQ"
     gene            3823..4491
                     /locus_tag="IXR05_002619"
     CDS             3823..4491
                     /locus_tag="IXR05_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAQ4261068.1"
                     /translation="MNKQELIDELAKYVKRYENVMDEHGQGRYGAYEVSLKLVKRLNE
                     SKITDEQAWNKVAEAYPESAQSLRNTLDNAVFGKTGEPQKHVMPKFVAEWIEYAKKKG
                     DSLAISFKPWNLYGVEYSKADRWIGDNQETFARAWLDGYEVEKEPLYYVPLPYEVWDE
                     EAAELKTEYLYLHYEITSDETRIFPTKEPRKGFVAKLDELTIKSADENYWPFAVPVEE
                     VVEG"
     gene            4488..4865
                     /locus_tag="IXR05_002620"
     CDS             4488..4865
                     /locus_tag="IXR05_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261069.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQVKMVQISHLQLEL
                     EDLRQIEDPYQLNDNQQIVLEWLKLTASTGKPMQVVFWMMNNAAWGHLDELRDPLMEL
                     TDKQQFEVLTAFAQWGLEQEEKE"
     gene            4862..5161
                     /locus_tag="IXR05_002621"
     CDS             4862..5161
                     /locus_tag="IXR05_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261070.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKLLAKSKDNLAVVRLVDMEVINNEI"
     gene            5403..5819
                     /locus_tag="IXR05_002622"
     CDS             5403..5819
                     /locus_tag="IXR05_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAQ4261071.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
BASE COUNT         2231 a          899 c         1391 g         1481 t
ORIGIN      
        1 aaataagcct caaagatgaa tcgaatacga ctgtgagtga tgctaatgtc ttagcaaata
       61 tcatcttaga tttcatcttt gaacatcata ttcctttcaa agaaggctat gagattttac
      121 cagcgaatca agaatattac ttctacaaat gcattacaaa aagagtttgt tgcatctgtg
      181 gcaaaacagg agctgacatc gatcactttg acaaagcgct aggaagacga aagcgaaaag
      241 aagttgatca ttcagagtac acatttgcag cactctgcag aatccatcac acggagaagc
      301 acaaaatagg tgtgatcaat tttaaaaata aatatcaaat caaaggaatc aagttaagtc
      361 atgaaacgat taaaaagtta aggataggag gataaatttg gctgagataa gttggatcaa
      421 acttaaaact actatgtttg acgatgaaaa aatacggtta atccaagctg ttcctgagtc
      481 ggatgccatc atcgttatat ggattcgatt actagtttta gcaggaaaga ctaacgacga
      541 tggtctgata tatatccaga ggaacatgcc ttataccgaa gaaatgcttg ctacattgtt
      601 tggcaaaaac gtaaatacgg ttcgcttagc gctaactaca ttggcaaatt tcaacatgat
      661 tgatctaagc agtgatggac taattgccat cagtaattgg gaaaaacatc aaaatatcga
      721 gggtatggat aaagtaaggc taaaaaatgc tgaaagaaac cgtaaataca gggaaagaaa
      781 gagacaggaa cgtctcaaat tggaaaatga cgttagcgtg acgtcacgtg acggtacaga
      841 taaagatata gaagaagata aagatataga taaagaagaa aagaaaggta agtattctga
      901 cgaacactta cgccttgcta aaaaaatgca aaggaattta actgaagatt ttccaaaaga
      961 aatgaacaaa gtagatatcg aaaaatgggc agacacaatc aggttgatgg aagaaagaga
     1021 taaagcatct atagaagcga ttgagtatgt gatcaattgg ctacctacaa atgaattttg
     1081 gtttggaaat attagaagtg ctaagaaatt gagagaaaaa tttgagaagc tcaaattcga
     1141 aatcaaagca gacaagaaga atcataaaaa gcaaagtcaa aaactacagt acagcaatcc
     1201 tagtgaatat gacgacttgc caatttaaaa ggagatgcat cacatggaaa gcctagcaaa
     1261 tgctatggag aagctaataa gaagagtatt agtgcaaagc ggaaaatgtc cagaatgtag
     1321 cgaacctttg tatagttggc gagctaaaaa taaggatggt tcagaacgtt gtaaaccaac
     1381 atgtatgagt tgtggttata aagcgttacg tgtgaaagag gatatacaga ccgaacggat
     1441 atataacgac agcttaaaag cacgagcatt gagttttttt caaaatggtt cggtattaac
     1501 agataaaact ttgtttaaat gcaaaatgga gaattatcac gtagtggacc aagaaacgaa
     1561 aattgcttta gaaagagcta aaagctatgt aaatgatgtc ctactgaacc atcctgcaca
     1621 tttcattcta tcagggaaat caggaagcgg aaaaagccac ttatcaatgg cgacagcttg
     1681 ggaaatactt gagcgctcaa attatgacaa gaaaatactt tttataagct atcaagagtt
     1741 attagagcaa ataaagtttt cttataacaa tgctgaactg agaaaagaaa ttgaaggatc
     1801 gcttatagcc gatatcaaaa caactgattt ggtggttttt gacgatattg gagctgaatt
     1861 aggtagcggg gtatcaaata gtaggcaatt tacaaacaac acgttaaaca cgctcttaga
     1921 agccagacag aacaaggcaa cgatcatcac aacaaactta tctggtcctg aactaagaga
     1981 agcctacggt gaaagaattg tttctaggat atttaagaat tcagaaggtt atgcgctgaa
     2041 attccaacaa acagcagaca agcgcataaa accagtgaaa ggtagtatcg catgaataaa
     2101 taccgtaata aaaaaactgt tcatcgaggt atcaagtttg attctatcgc agaagcagag
     2161 tattacgatc tagccttgtg gcaagctgaa gcgaacggct ggaaagtaaa acttcaggaa
     2221 agatttgagc tgatgccgaa atttgaacta gacggaaaga agtatcgcaa gatcgagtat
     2281 attcccgact tcacatttta taaaaacggc aaactagtca aagtcgtaga tgttaaaggg
     2341 atgcagacaa aagatttcaa aatcaaagcg aaactcttct gcagtcaata tcgagtacca
     2401 ctgatcttag cgaagaaata tcggaatacg ttcaaggaag aacggtttta acgaggtgat
     2461 ccatcatgac aacagaagaa gtgattcaaa tgcgtattcg aagccttcag cgtgagattg
     2521 acgatctgta acggacaaag gcagtgatgg tcaatgaaac ggcgaggaag gcaatcgatt
     2581 tgcacataga aaatttaaga aggaaaatcc atcgattgga ggaatgagcg tggataagaa
     2641 agcagcaatg aaacgaatca tcgaactgac acattctgag aattggcaag aagacaaaga
     2701 aatagttgca gaagtccaaa agctcggtaa atcaatgtgg gctgaaaagc ctaaacggaa
     2761 aacgccgaga aaaattgcaa tctggcatgg tgatcgaatt ctagtaacag gtactgctga
     2821 acagttatct gaaattactg gattaagcaa aaacattatc tgggatagag ctaggagctt
     2881 atggattgat tcaaaaggac gacagtttag gtatgtggag gagaaataat gaacgaacta
     2941 atcacaaaag tagagcagtg ggctaaagac aagggactgg atcaagcgga tccaaaagca
     3001 caatttttga aagtagctga ggaattcgga gaaattgcat cggcaatggc aagaagtaat
     3061 gatgagctat ttaaagatag cgtaggagac gttatcgtca cgctgattat tctttccatg
     3121 caaaaagggg caaacataca agagtgttta gaaatggcgt ataacgaaat caaaggacgc
     3181 acaggaaaaa tggtagatgg tgtattcgtg aagtcgagtg atttggagga cagcgaatga
     3241 tgatgccaaa agaaatctat tcagatgcat taagaggtgc tagaaatcaa ttgaaaatgg
     3301 caaaaagagc atacgaaatt cggcccacaa tcgaaaatga acgcagagta aaagcaattc
     3361 gccgtagatg ttcaatttac ggcgagttac agaaggagga cagcaaatga taccgagatt
     3421 tcgagcttgg gataaacgaa agaacgtaat gagagatgta gccgtcttgc attttactaa
     3481 aaacggcaaa acaaacttta ttgaatattg gataaatcct accgaattga aatcatatca
     3541 cgtgcgaaac atcgagctca tgcaatcaac agggctgaaa gataagaatg gcattgagat
     3601 tttcgagtgg gatattgtat cagtcagcgt gcgaaatgga ttcgattatt tagataataa
     3661 agtttgtgtt gtcaaaaatt caataggaca ttcgggatta gtgtgtgcca ctgttgatga
     3721 agatttagag tatcaaattt ttaacacaga gctgtttgaa gaatacacgt atgaagtcat
     3781 cggaaatatt tgggagaata gcgagttatt ggaggaacag tgatgaataa acaggaattg
     3841 attgatgaat tagctaaata tgtaaagcgt tatgagaacg ttatggatga gcatggccaa
     3901 ggaaggtacg gcgcttatga agtatcttta aagttggtga aaagactaaa tgaatcaaaa
     3961 attacggacg aacaagcttg gaataaggta gctgaggctt atcctgaatc ggcacaaagc
     4021 ttgagaaaca ctttagataa tgctgtattt ggtaagactg gtgaaccgca gaagcacgtt
     4081 atgccgaagt ttgtggcgga gtggatagaa tacgctaaaa agaaaggtga tagtctagct
     4141 atttcattca agccgtggaa cctctatggt gttgagtata gcaaggctga tagatggatt
     4201 ggagataatc aagaaacgtt tgctcgtgct tggctagacg gctacgaggt cgagaaagag
     4261 ccgttgtatt atgtcccgct accatatgaa gtttgggatg aagaggcagc ggagcttaaa
     4321 acagagtatt tgtatctaca ttatgagatc acaagtgatg aaactagaat atttcctaca
     4381 aaagaaccta gaaaaggttt tgtcgcaaaa ttagatgaac ttacgattaa atcagcagat
     4441 gaaaactact ggccgtttgc tgtaccagtg gaagaggtgg tagaaggatg aaaaaattgc
     4501 accaactcat atctgagaaa gaaagcgaac tccaaaattt agaagatagt ttgggattgg
     4561 ggtttccaat tgttgagcaa gttaaaatgg ttcaaatcag tcatctacaa cttgaattgg
     4621 aagatttaag acaaatagaa gatccgtatc aactcaacga taaccagcaa atcgtgttgg
     4681 agtggttgaa actaactgcg tcaacaggaa agccaatgca agttgtattt tggatgatga
     4741 ataatgcagc atgggggcat ttagacgaat tgagggatcc tttgatggaa ttaactgaca
     4801 aacagcaatt cgaagtccta acagcattcg ctcaatgggg attagaacag gaggaaaaag
     4861 aatgaaacta aaagacggat tttacgctag tagccacggt atcggcggtt taatgctaga
     4921 catgccgaca aagaacccta aaacacgtaa gaagccaaaa gtcaaagtcg gtgacatggt
     4981 tcgctgtgaa gcagaaggat tcatctatcc atttcgtgga tatgtagaac acgtctataa
     5041 tcactcagcg atcattcgca ttgaaaacac gatggaatgc gacaagttat tagcgaaaag
     5101 caaagataat ttagcagtgg tgagattggt ggatatggag gttataaaca atgaaattta
     5161 aaatctttga agaggacact cgctataaat tagaaaaaaa attaaatgaa tttgcaaaga
     5221 ataatgaaat tcagcatata tctttaacgg cttctaagtc aggttataca acttactatg
     5281 cagctgttgt gagctacgta attcaataaa aggaactcgg caaataaaaa agccggatca
     5341 ctccgactga tgtaataaat ccgacaagtt tattatatca cataaaggag cggtttgact
     5401 tgatgcaatt gttacgagag gtagatttca aacagacaag atgtaatgcg agagatgtgc
     5461 tgaagaactt tcggcgcttg gagcggatgg caggtcgctc tttgatagat attaagtcgc
     5521 cgattattac ggatatgccg aaggcaccga agcacggcaa taaggcagaa gacgcgatca
     5581 ttcagatgat ggatatagaa gcggagagag acgcgatttt agcggctttg atggcgctta
     5641 gtctgattag ccgtcagata ctctactaca gcttctgtga cgtaaacaag cactctaatt
     5701 atgaaatagg gcaattgata cgaggatacg gagagaagaa tgtagagaag ctgaaatcca
     5761 tcgcattgat cgaatttgct gaagcataca aaaaaggcgt gttagttcag tatcgttaat
     5821 tttgtagggt ttttgtaggg atagtgtagg gtttttgagc ggtttaacgt gatattatga
     5881 tagtgtcgaa agattagtga taggtctaag acaaaataat aataaaagga acatcgtttt
     5941 attattgttt cacaattaag cttcgataga cagcagcgga aatattaaga ataaggatgt
     6001 ga
//
LOCUS       DACGDM010000126         5903 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.134, whole genome shotgun sequence.
ACCESSION   DACGDM010000126 DACGDM010000000
VERSION     DACGDM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.134"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..985)
                     /locus_tag="IXR05_002623"
     CDS             complement(<1..985)
                     /locus_tag="IXR05_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HAQ4261072.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIG"
     gene            1137..1832
                     /gene="vanR"
                     /locus_tag="IXR05_002624"
     CDS             1137..1832
                     /gene="vanR"
                     /locus_tag="IXR05_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAQ4261073.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1810..2964
                     /locus_tag="IXR05_002625"
     CDS             1810..2964
                     /locus_tag="IXR05_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAQ4261074.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            3179..4147
                     /locus_tag="IXR05_002626"
     CDS             3179..4147
                     /locus_tag="IXR05_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAQ4261075.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            4140..5171
                     /gene="vanA"
                     /locus_tag="IXR05_002627"
     CDS             4140..5171
                     /gene="vanA"
                     /locus_tag="IXR05_002627"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAQ4261076.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            5177..5785
                     /locus_tag="IXR05_002628"
     CDS             5177..5785
                     /locus_tag="IXR05_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAQ4261077.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1782 a         1149 c         1335 g         1637 t
ORIGIN      
        1 ttccgataac cgtgtattga aaggcatctt cgaagccatt atccaatatt tcgcaggctt
       61 ttgtatattt aggctggtcg atatattcac cgactaaggc attcttagct gttcgagcga
      121 gttcaatatc cgtaaactta aagatcgctt ttactgcttc tctaaacggt tttgaattct
      181 tttttggaat ggaactgaag atgtttctta aaaaatggac ctggcatctc tgccaacttg
      241 cgttggtaaa tgacttacga atcgcagaca ctaggccttt atgggcatca gaaatgatga
      301 gttctgtccc ctttaggccg cgttctttta agtattcaaa gaagatggac catgtgtcat
      361 cactttcttc attttgaatc atgaagccaa tgatttcacg gtcgccacct tctgttatcc
      421 cgatcgcaat atggcagctt ttagaaagca ctcgatggtc ctcacggact tttatgtaga
      481 gaacatcagt catcagataa ggataattcg tacctgagag tgaacggttc tgccattcgt
      541 tgaccatcgg gtctaactgc tcagtcaggc tagaaacaaa agatttcgat acagattttc
      601 cacatagctc ttcaacaatc tttgaaactt tacgtgtcga aacgcccgaa acatacatct
      661 caagcattga agcgagcagt gccttttcat ttcgctgata acgctcaaac accgtcggtg
      721 aaaattcacc atcacgtgtt ctaggcactt ttaattcgag tgtacccaca cgagtcgtaa
      781 agtctcgctc ataatagcca tttctttgac tctgacgact ttctgaacgt tcatagtcat
      841 cggcttgaat atattctgtt cgttgatttt ccatcaattg gttgaaaaca gtggttaaaa
      901 tatttttaga aacatcatct tttaccgaat gttcaataat actttgaacc tcttcgttgt
      961 tcagtgtaaa atgtacttgg gtcatgtaac gtcctcctgg gtatgttttt gtggttaaaa
     1021 acattgtacc gtaaaagggc tgttacatgg ccttttatct tttacacaat tatatggact
     1081 ttatcctata atctgataaa ttattaaggg caaacttatg tgaaagggtg ataactatga
     1141 gcgataaaat acttattgtg gatgatgaac atgaaattgc cgatttggtt gaattatact
     1201 taaaaaacga gaattatacg gttttcaaat actataccgc caaagaagca ttggaatgta
     1261 tagacaagtc tgagattgac cttgccatat tggacatcat gcttcccggc acaagcggcc
     1321 ttactatctg tcaaaaaata agggacaagc acacctatcc gattatcatg ctgaccggga
     1381 aagatacaga ggtagataaa attacagggt taacaatcgg cgcggatgat tatataacga
     1441 agccctttcg cccactggag ttaattgctc gggtaaaggc ccagttgcgc cgatacaaaa
     1501 aattcagtgg agtaaaggag cagaacgaaa atgttatcgt ccactccggc cttgtcatta
     1561 atgttaacac ccatgagtgt tatctgaacg agaagcagtt atcccttact cccaccgagt
     1621 tttcaatact gcgaatcctc tgtgaaaaca aggggaatgt ggttagctcc gagctgctat
     1681 ttcatgagat atggggcgac gaatatttca gcaagagcaa caacaccatc accgtgcata
     1741 tccggcattt gcgcgaaaaa atgaacgaca ccattgataa tccgaaatat ataaaaacgg
     1801 tatggggggt tggttataaa attgaaaaat aaaaaaaacg actattccaa actagaacga
     1861 aaactttaca tgtatatcgt tgcaattgtt gtggtagcaa ttgtattcgt gttgtatatt
     1921 cgttcaatga tccgagggaa acttggggat tggatcttaa gtattttgga aaacaaatat
     1981 gacttaaatc acctggacgc gatgaaatta tatcaatatt ccatacggaa caatatagat
     2041 atctttattt atgtggcgat tgtcattagt attcttattc tatgtcgcgt catgctttca
     2101 aaattcgcaa aatactttga cgagataaat accggcattg atgtacttat tcagaacgaa
     2161 gataaacaaa ttgagctttc tgcggaaatg gatgttatgg aacaaaagct caacacatta
     2221 aaacggactc tggaaaagcg agagcaggat gcaaagctgg ccgaacaaag aaaaaatgac
     2281 gttgttatgt acttggcgca cgatattaaa acgcccctta catccattat cggttatttg
     2341 agcctgcttg acgaggctcc agacatgccg gtagatcaaa aggcaaagta tgtgcatatc
     2401 acgttggaca aagcgtatcg actcgaacag ctaatcgacg agttttttga gattacacgg
     2461 tataacctac aaacgataac gctaacaaaa acgcacatag acctatacta tatgctggtg
     2521 cagatgaccg atgaatttta tcctcagctt tccgcacatg gaaaacaggc ggttattcac
     2581 gcccccgagg atctgaccgt gtccggcgac cctgataaac tcgcgagagt ctttaacaac
     2641 attttgaaaa acgccgctgc atacagtgag gataacagca tcattgacat taccgcgggc
     2701 ctctccgggg atgtggtgtc aatcgaattc aagaacactg gaagcatccc aaaagataag
     2761 ctagctgcca tatttgaaaa gttctatagg ctggacaatg ctcgttcttc cgatacgggt
     2821 ggcgcgggac ttggattggc gattgcaaaa gaaattattg ttcagcatgg agggcagatt
     2881 tacgcggaaa gcaatgataa ctatacgacg tttagggtag agcttccagc gatgccagac
     2941 ttggttgata aaaggaggtc ctaagagatg tatataattt tttaggaaaa tctcaaggtt
     3001 atctttactt tttcttagga aattaacaat ttaatattaa gaaacggctc gttcttacac
     3061 ggtagactta ataccgtaag aacgagccgt tttcgttctt cagagaaaga tttgacaaga
     3121 ttaccattgg catccccgtt ttatttggtg cctttcacag aaagggttgg tcttaattat
     3181 gaataacatc ggcattactg tttatggatg tgagcaggat gaggcagatg cattccatgc
     3241 tctttcgcct cgctttggcg ttatggcaac gataattaac gccaacgtgt cggaatccaa
     3301 cgccaaatcc gcgcctttca atcaatgtat cagtgtggga cataaatcag agatttccgc
     3361 ctctattctt cttgcgctga agagagccgg tgtgaaatat atttctaccc gaagcatcgg
     3421 ctgcaatcat atagatacaa ctgctgctaa gagaatgggc atcactgtcg acaatgtggc
     3481 gtactcgccg gatagcgttg ccgattatac tatgatgcta attcttatgg cagtacgcaa
     3541 cgtaaaatcg attgtgcgct ctgtggaaaa acatgatttc aggttggaca gcgaccgtgg
     3601 caaggtactc agcgacatga cagttggtgt ggtgggaacg ggccagatag gcaaagcggt
     3661 tattgagcgg ctgcgaggat ttggatgtaa agtgttggct tatagtcgca gccgaagtat
     3721 agaggtaaac tatgtaccgt ttgatgagtt gctgcaaaat agcgatatcg ttacgcttca
     3781 tgtgccgctc aatacggata cgcactatat tatcagccac gaacaaatac agagaatgaa
     3841 gcaaggagca tttcttatca atactgggcg cggtccactt gtagatacct atgagttggt
     3901 taaagcatta gaaaacggga aactgggcgg tgccgcattg gatgtattgg aaggagagga
     3961 agagtttttc tactctgatt gcacccaaaa accaattgat aatcaatttt tacttaaact
     4021 tcaaagaatg cctaacgtga taatcacacc gcatacggcc tattataccg agcaagcgtt
     4081 gcgtgatacc gttgaaaaaa ccattaaaaa ctgtttggat tttgaaagga gacaggagca
     4141 tgaatagaat aaaagttgca atactgtttg ggggttgctc agaggagcat gacgtatcgg
     4201 taaaatctgc aatagagata gccgctaaca ttaataaaga aaaatacgag ccgttataca
     4261 ttggaattac gaaatctggt gtatggaaaa tgtgcgaaaa accttgcgcg gaatgggaaa
     4321 acgacaattg ctattcagct gtactctcgc cggataaaaa aatgcacgga ttacttgtta
     4381 aaaagaacca tgaatatgaa atcaaccatg ttgatgtagc attttcagct ttgcatggca
     4441 agtcaggtga agatggatcc atacaaggtc tgtttgaatt gtccggtatc ccttttgtag
     4501 gctgcgatat tcaaagctca gcaatttgta tggacaaatc gttgacatac atcgttgcga
     4561 aaaatgctgg gatagctact cccgcctttt gggttattaa taaagatgat aggccggtgg
     4621 cagctacgtt tacctatcct gtttttgtta agccggcgcg ttcaggctca tccttcggtg
     4681 tgaaaaaagt caatagcgcg gacgaattgg actacgcaat tgaatcggca agacaatatg
     4741 acagcaaaat cttaattgag caggctgttt cgggctgtga ggtcggttgt gcggtattgg
     4801 gaaacagtgc cgcgttagtt gttggcgagg tggaccaaat caggctgcag tacggaatct
     4861 ttcgtattca tcaggaagtc gagccggaaa aaggctctga aaacgcagtt ataaccgttc
     4921 ccgcagacct ttcagcagag gagcgaggac ggatacagga aacggcaaaa aaaatatata
     4981 aagcgctcgg ctgtagaggt ctagcccgtg tggatatgtt tttacaagat aacggccgca
     5041 ttgtactgaa cgaagtcaat actctgcccg gtttcacgtc atacagtcgt tatccccgta
     5101 tgatggccgc tgcaggtatt gcacttcccg aactgattga ccgcttgatc gtattagcgt
     5161 taaaggggtg ataagcatgg aaataggatt tactttttta gatgaaatag tacacggtgt
     5221 tcgttgggac gctaaatatg ccacttggga taatttcacc ggaaaaccgg ttgacggtta
     5281 tgaagtaaat cgcattgtag ggacatacga gttggctgaa tcgcttttga aggcaaaaga
     5341 actggctgct acccaagggt acggattgct tctatgggac ggttaccgtc ctaagcgtgc
     5401 tgtaaactgt tttatgcaat gggctgcaca gccggaaaat aacctgacaa aggaaagtta
     5461 ttatcccaat attgaccgaa ctgagatgat ttcaaaagga tacgtggctt caaaatcaag
     5521 ccatagccgc ggcagtgcca ttgatcttac gctttatcga ttagacacgg gtgagcttgt
     5581 accaatgggg agccgatttg attttatgga tgaacgctct catcatgcgg caaatggaat
     5641 atcatgcaat gaagcgcaaa atcgcagacg tttgcgctcc atcatggaaa acagtgggtt
     5701 tgaagcatat agcctcgaat ggtggcacta tgtattaaga gacgaaccat accccaatag
     5761 ctattttgat ttccccgtta aataaacttt taaccgttgc acggacaaac tatataagct
     5821 aactctttcg gcaggaaacc cgacgtatgt aactggttct tagggaattt atatatagta
     5881 gatagtattg aagatgtaag gca
//
LOCUS       DACGDM010000127         5888 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.135, whole genome shotgun sequence.
ACCESSION   DACGDM010000127 DACGDM010000000
VERSION     DACGDM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.135"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(170..3319)
                     /locus_tag="IXR05_002629"
     CDS             complement(170..3319)
                     /locus_tag="IXR05_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAQ4261078.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3333..4550)
                     /locus_tag="IXR05_002630"
     CDS             complement(3333..4550)
                     /locus_tag="IXR05_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAQ4261079.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4540..>5888)
                     /locus_tag="IXR05_002631"
     CDS             complement(4540..>5888)
                     /locus_tag="IXR05_002631"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAQ4261080.1"
                     /translation="IVDILGYSISPEYLFNVLADQAKQATFQLNDLNKAFVQLASTYN
                     QFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKKLNDVEVLGHDGDVIGDAYEFLISQF
                     ASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERRFFSVFDPTMGSGSLMLNVRNYLTHP
                     DNVKYHGQELNTTTYNLAKMNLILHGVDAEEMNLRNGDTLNKDWPTDEPYTFDAVVMN
                     PPYSANWSADTTFLDDSRFNRYGKLAPKSKADFAFLLHGFYHLKETGTMAIVLPHGVL
                     FRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGTSIPTTVIVLKKNRQTRDVLFIDASR
                     EFVKGKNQNKLSEENIQKILETYAERKDVEKYAHLATFDEIKENDYNLNIPRYVDTFE
                     EEEPIDMVHVGNDIKKIRQEQQVLEKELLEAISSLQTTPENEAWLQGALEVFKHEQ"
BASE COUNT         1611 a         1252 c          985 g         2040 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagattag
      361 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaaggcatga atcaaattat
      421 cacttgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
      481 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
      541 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
      601 ttcctagtaa ttgatcaata taagtagaat caatatcata caacttagtg gtattttcac
      661 tataaaattc gatcgttgaa aaatcttctc cctctttttc tggttcttcc tccatcaatg
      721 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
      781 aagttgaaga ttgcaccatg tcatcattgt aatcatcata agtcactaac gattcatacg
      841 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
      901 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgc ttgaatcttt
      961 ttttggattc ttggtaactt ggataaatca aacccgattc ttctttagct tctgaataca
     1021 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg ctttcggaaa gtaacaatta
     1081 gtccttttgt tttttcagga tacgtacggt tcgtacgtga aaaggcttgg atcaatcctg
     1141 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtca
     1201 atagacgatc cactacgatt actaaatcga tttgtttccc aaattgtttg aattccgctc
     1261 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctagtgacc
     1321 aggcagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     1381 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt gggaaatcag
     1441 gatcctccat cgttcgtcct tcacggatag gctgattggg aaactctttt attaaccaat
     1501 cagattcttt cgtcatctct ttgatggccc gataatactt tttggccata tcaatggaac
     1561 tcgtggttaa gatcgcagac ttcgttggac ggccatttcg aaaatcaaat tttgtatagg
     1621 cattgtctgg acggaacatt ttatgaatga ctttttggat atgttcctct gcttcaaaaa
     1681 cagtagggtc caaataactt tcttttttga cagactccat ttgatcgatc atacgattga
     1741 tctgttccgg tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     1801 tctctaatga agtcggctcc acggtgtttt catgctctac ttgaaatcct aaaaccgagc
     1861 catcttctaa tgcattcttg atggtatagg tgtgcaagac ctctccatac tgatcatggg
     1921 tcgtacgtgc caattgccct ttggcttgtt tccgattctc agggaaaatc ggtgtacctg
     1981 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     2041 ttaacgctcg atgacactca tcaactacaa acacgatatg ttgccccatt aatttttgga
     2101 agcgattggt tccttttttc tcttcctgtt tctttgcata tttcaacgcc gcatctagtt
     2161 tttgacgggt tgtaatgatc acaacattcg cattggcatc tgccaacaga gtttcactta
     2221 actctttggc acttcctgtt cccacgatca agctattcgc tttggcatta ccagaagaaa
     2281 ccccagtatt aaactccgaa gcaaatttcg taaactctgt ggtggtctga ttatctaaat
     2341 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     2401 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     2461 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg cacttgataa ggatgtaaca
     2521 ccatgagggt tttattgtct tgatcttcac tgacaatcgt ataatccgca atcaagcgat
     2581 gggcatctgg gatatttagc acttgtttgc aaaactcata taagttttct acctttttat
     2641 tatctttcgt tcgccaacta aataaaaact taggatgcaa atccttcggt aaggcatttg
     2701 caaaataccg agtcgtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     2761 tgttccgaaa catgccttct tcagcatatt ttttgatttg attaaacgcc tgataaaaac
     2821 catcttttgc agttacttgt tttagctcga tttggataat cggtaagcca ttgatcaata
     2881 aggtgacgtc aaaacgtcga tcccgcgctt ctatgttact tccacgtttt gcaatttgat
     2941 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
     3001 agacagaacc caattgcgga ttttcccgtt caatcgtgat ccgagccatc ccattttcac
     3061 cttttaacca tttcgcagca tcaaatgggg ttttcgtccg tagcaataat tcggttttga
     3121 tcgtttcaaa ctctttatcg gtcaaaggag aatcattcag ttctgcttga ttatttgaga
     3181 tgattttttg acgtaaattg ctccaaagat cttcttctga ttttagatcc ggacgatacg
     3241 tccactgatt atgtccttcc ccgaggacac gaatcaactg ttcttcgact tccgcttcct
     3301 cacggtgact aattttcatt cttcttccct ccctaaacaa acatcttttg caagaagcct
     3361 tttttcgttt ccttcagcaa atctaactta cgttgatgaa gagcgatcgt atcatctagc
     3421 tgcttgaaga aggcaccaat tttttgttgt tcatttatat ccggtggaaa ctgaaatgtc
     3481 ctttgttcta taccaccttt agtcacatgt accattgtcg ttccgttagt tgattcttta
     3541 attttctctt tatcagtcaa tagccaagta tatagatact gtttgtccaa ttccttagat
     3601 aaaaatttaa gtttccaaat atgataatgg tagattacac gttcttcatt ccacatttca
     3661 ggaccgaagc ttgttgccca taaatataag agatctcctt tattagcata cttgtcttcc
     3721 tctaattcta agtttgaata ataccatcta tcattagtat taaaattacc tactcttaaa
     3781 accctatatt ttccagaatc aagtaattct tgttgtttaa aagctctacc attcaaaaaa
     3841 actaccactt cccccaactt ccgctcttcc caatctcccg taaatcctgg aaaacgaact
     3901 tctggcactt ttgctccgtt tttagggaac attttttgta agaatccttt tttcgtttcc
     3961 ttcagcaaat ctaattcgtg ctggtgaagc atgatggtgt gatcaagttg tttgaaaaat
     4021 gaaccgatct tgatctgttc gtcataagtt ggaagtgaga taggtgtctt tttaccacta
     4081 tcaattgtat aggttccgac ggttccaatg cctgcaacgt cacggatata cttctgaatt
     4141 ttgttattta tgaacgagta gtaaaagaag tttccgtcaa ttttatgctc attcttgaac
     4201 caaatgatgt ttccatcctt aaagtaaatt gggttatcat cagtgattaa taaggggaca
     4261 cctattgatc cgacaccagt tacaagcaag tctccttgag aaactttacc tgaatttttc
     4321 gaatattcat tatatttttc ttctgaaatg taaagataat cggatggttc ctcatttttt
     4381 gcagctgaga caatatcacg agcacgtaaa aatctaatac ctgagttagt ccaatctgat
     4441 tgatgaattc gcttcacaga agtaacatcc atcatatctc ctaacttacg ctcttcccaa
     4501 tcttccgtaa aaccaggaaa ccggatttct ggtcgtgtat cattgctcat gtttgaacac
     4561 ctccagcgca ccttgtaacc acgcttcatt ttcaggtgtt gtttgcaggg aagagatagc
     4621 ttctaaaagt tctttttcta gcacttgctg ttcttgtcgt atcttcttga tgtcatttcc
     4681 gacatgaacc atatcaattg gttcttcttc ttcgaaagta tcgacatagc gtgggatatt
     4741 taagttatag tcattttctt tgatttcatc aaaggttgcc aaatgagcgt atttctcgac
     4801 atcttttctt tcagcgtagg tttcgaggat tttttgaatg ttttcttccg ataatttatt
     4861 ctgatttttc cctttaacaa attcacgact agcatcaatg aataatacat ctcgagtttg
     4921 acgattcttc ttcaatacaa tcaccgtcgt tggaatcgat gtaccaaaga acaagttcgc
     4981 aggcataccg atcacagcat aaatactgcc gtcttctaat aatttttgac gaatgacccc
     5041 ttctgcagca ccacggaata aaaccccgtg tggcaagacg atagccatag tccctgtttc
     5101 cttcaaatga tagaaaccat gaagaagaaa cgcaaaatct gctttggatt ttggcgctaa
     5161 tttcccgtag cgattaaacc gagaatcatc taagaaggtc gtatctgctg accaattagc
     5221 cgaataaggt ggattcatca ctactgcatc aaatgtgtaa ggttcatctg ttggccagtc
     5281 cttattcaac gtatccccat tgcggagatt catttcttcg gcatctaccc catgtaaaat
     5341 caagttcatt tttgctagat tgtatgtcgt tgtatttagt tcttgcccat gatatttaac
     5401 gttatctgga tgagttaagt agttacgtac atttaacatc aaggaacctg aacccatggt
     5461 tgggtcaaag acactaaaga atcgtcgttc tttttgatcc aacgtcacga tttgtgccat
     5521 catatcagaa accatatgag gcgtgtaaaa ttctccggct ttcttccctg cttctgaagc
     5581 aaattgactg atcagaaatt catacgcatc cccgatcaca tccccatcgt gacctaaaac
     5641 ttccacgtca ttcaatttct tgataacttc ggtaatcgtc acatttcgtt gttgctcatc
     5701 tgttcctagt ttttttgatt ggagatccac atcatcaaat aacccattaa attgattgta
     5761 ggtagatgcc aattgcacaa aggctttgtt tagatcgttc aattggaacg ttgcttgttt
     5821 tgcttgatcc gctaagacgt tgaaaagata ctctggtgag atcgaatacc ccaaaatatc
     5881 aacgattg
//
LOCUS       DACGDM010000128         5809 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.136, whole genome shotgun sequence.
ACCESSION   DACGDM010000128 DACGDM010000000
VERSION     DACGDM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.136"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            450..1604
                     /locus_tag="IXR05_002632"
     CDS             450..1604
                     /locus_tag="IXR05_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAQ4261081.1"
                     /translation="MIILKPKNKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1598..2020
                     /locus_tag="IXR05_002633"
     CDS             1598..2020
                     /locus_tag="IXR05_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261082.1"
                     /translation="MVNKPIVLVMGLVLVLFLTSCSKKQEIQKTELIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            3143..4075
                     /locus_tag="IXR05_002634"
     CDS             3143..4075
                     /locus_tag="IXR05_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4261083.1"
                     /translation="MANEIVKYKPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFDQLKDLSAYKQTAGEVFIKDLTRTYDHLMDLRFGKKSNGGLTIERFTMFTDFEIH
                     GEADNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRTKLFNIEHNGELTQEEKWRAKDRILDLPLGTHEAN
                     FKKQQQTEKEEVEKQTLSNELKQDLLGNLQNLFD"
     gene            4092..4607
                     /locus_tag="IXR05_002635"
     CDS             4092..4607
                     /locus_tag="IXR05_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAQ4261084.1"
                     /translation="MADKTIKDLAEELGVSKTAINKKVSDENRKLWFAKIGNKFVINE
                     IGQKAIKSMFFTENENSNQQPVGEKSKTENHKNANQVSELELFFFLEKQLNQKDIQLQ
                     EKDEQLKQMQKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQ
                     NKEKKWWQFWQ"
     gene            4903..5184
                     /locus_tag="IXR05_002636"
     CDS             4903..5184
                     /locus_tag="IXR05_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261085.1"
                     /translation="MDILVRNINPKIITRVDKRCQELTTKTGEKWSRNKYLKVLIESD
                     FDRQLMNYKKEQFDLLLEKFIDIQTKNTETLNDYVHTNNQLIETLIGGI"
     gene            5186..5602
                     /locus_tag="IXR05_002637"
     CDS             5186..5602
                     /locus_tag="IXR05_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261086.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EKQLNPSQRNQPKNRQKETSQTFTSKNFDPTNFLKR"
BASE COUNT         2227 a          961 c          931 g         1690 t
ORIGIN      
        1 aaaaaaaaag actgctcgaa agagcagtct caagcaaaaa ataaacgaac aaacgcaatt
       61 actcacgaac acaaacaaat acaataaaat acctaaataa tgaaaataag tgataaaaaa
      121 caagggtatt tatagtttaa caagcgctca taaaaataac aagtctttaa aaaatgacag
      181 ataaaaatgc acaaagaatc ggacacagat aaccgcgaaa aatcaagctt tagaaagttg
      241 tttttagcta gaccaatgaa aaatcacaaa gtccgcccct gtatccgttg gtagaggggc
      301 tacttggttt agtgtacatt atgttaacta gctcgttaaa taacgattat gttcccaaaa
      361 caatatttta tgaactataa caaaaatttg ttatcgcata ttgtatattt taattatagg
      421 tgtatatcac ttaattttaa cacaaaggcg tgattatttt gaaacccaaa aataaaattt
      481 atctaggtct cctcttttcc ttgatgattg gaatttttag tataggaatt acaaatacct
      541 atgcttcaga aaattctaat ttcaatatca actcccaacc aattgaagaa caagcaatta
      601 attttgcgaa aactgatttt gaacactcca taacttcaat tcttttaatg gaaaataaca
      661 ctgaaactga tattaactat actcttggtt cgccatttaa aatgctcgat ggagaaaata
      721 cggcaaatag ttctattttc tttccagtat tttcagacgc tgataatacg attaaatatg
      781 tttataccgt caaaaaaaat acaaatggag aatattcagg aagtatttca caatttttag
      841 caaaagaact tcaaaatcta gtagatagca atataacaga tacaacctta ttttttcaag
      901 ataatagcat ttattattcc gataatggcc aaattaaact actttggaaa tcacctttaa
      961 gtacagaaaa aaatggtgtc tcttccttta cagaaaaaaa tgatcttata tccgtaaata
     1021 taaaaaataa aattaaaaat ttctctaaaa aacaaaattt tcctgcggtt aaacgtgtaa
     1081 aaagtgtctc ctccggagat aactttatta tgattaattg gcgtatagca gaaacccaaa
     1141 caagttttcc gtggtgcgct gcttacgtag aagctgctat cttatgtaat aaaacagatg
     1201 tacgcgctac ttcagctaga gccattatgc attataccta tcctaattta aacaacagtc
     1261 aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat tactgtggtg
     1321 tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca caactaagaa
     1381 aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac agccgtcatg
     1441 cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat gtgtggaatc
     1501 cttggtataa ctacccaact gtaataagtg caaatgcagg gccagttaca attcctgtac
     1561 ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac ccattgtttt
     1621 agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac aagaaataca
     1681 aaagactgag ctgattcctt ttctaggaac ttggcaaact aaagatcact cagaacgtct
     1741 agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct tagtaaaaga
     1801 gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac aagttttcat
     1861 ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat tagattacac
     1921 ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg atgggacaga
     1981 agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg tttgatatta
     2041 caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt ggctagcatt
     2101 tgctagcctt ttttgtattg cggagcgtga gttttgaggg ggattcaagg gggagtttct
     2161 cccctttgac aagcggttat ttgcaccaaa tacgaaggta tttggctagc aaatatagag
     2221 cttgccaaac cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca
     2281 aacgatacgt cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat
     2341 ttggctagca atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt
     2401 cgagtgagcg aatccgaatt tgcaaatctg aagctttgca aatgagtgtg ccggcttccg
     2461 taaaagtcta ggtaacatta gtcgatatat acataaggct ctaatttgcg ttttaaggcg
     2521 ttttaaacgt tctggtatgt aatttatacc aaagcgactt taaaacgcct taaaacgaat
     2581 tttataggtc ttgtaggacg tttcagggtt gttagggctt gccctgaccg cctgtaaggc
     2641 gctttaaaaa caagataagg gattttatct agacttgtct taaaacgccg tagatgagcg
     2701 ctcagagctt cttaaaggac tccttacgaa ctgtttttaa gcaaaggagc ctttaggcga
     2761 ctgcgcagtt caatgtgaga gcgtagcgat cacaccttta aagcgaccgt agggagcaga
     2821 ttcccagttt aggaaatttc gcgaacctgt ttggagaaaa aaagtaggaa atttttaggc
     2881 gggaaatttt gcccccctct tttataatct cttttataac ctctttttaa acctctttac
     2941 cgtcggctgt atccttactc tcccaaggcc tgtagctttt ttagggcatg aaattatctg
     3001 tttataggca tgaaattatc tgtttatagg catgaaatta tctgtttata ggcatgaaat
     3061 tatctgtttt aggtattgtt ttaagacata atatacctta aaattatgtc aataaaatta
     3121 gttagactgg agtatcaaat aaatggcaaa tgaaatcgta aaatataaac cagaattaaa
     3181 taccattcct ttaaggaaat ttactccaat agaaatgaac ttgttttttt ctattgtttc
     3241 tagaatgcgt gataaaggta atcaaaaaat acgcttttat ttcgatcagc ttaaagattt
     3301 aagtgcttat aagcaaactg ctggagaagt ctttataaaa gatttaacaa gaacatacga
     3361 tcatttaatg gatttacgtt ttggaaaaaa aagcaatggt ggattaacca tagaacgatt
     3421 tacaatgttt actgattttg aaattcatgg agaagccgat aacccttatg tggatataaa
     3481 agttcacgaa aaagctttgc ctttacttaa caatttagaa agttgggtac gtttctcttt
     3541 aacagaattt cgagatttaa atagcagtta tgctaaaaca atgtttagat tactaaaaca
     3601 ataccgaaca caaggatggg ctgaattttc caaggaagat tttttagaac tattagatat
     3661 tcctaaaagc tatagacaaa caaatataaa tcagtttgta ctcaaaccca taaaagaaga
     3721 actcacacca ttatttaaag gattaacgat tcgtaaaaaa tatggtaaag gccgaggcaa
     3781 acctgttatt ggttatcgtt ttacttggaa agctgaaatt aatcatgctg acgatttttc
     3841 aaaagggaag caagaagatt tacgtacaaa attatttaat attgaacaca atggagaatt
     3901 aacgcaagaa gaaaaatggc gcgctaaaga tcgaatacta gatcttccgt taggtactca
     3961 tgaagctaat tttaaaaaac aacaacaaac tgaaaaagaa gaagtggaaa aacaaacact
     4021 ttcaaacgaa cttaaacaag atttattagg aaatttacaa aacttattcg attaaagtat
     4081 aaggagtatt tatggcagat aaaacgatca aagaccttgc tgaagaatta ggagttagta
     4141 agacagctat taacaaaaaa gtttctgacg aaaatcgaaa actttggttt gcgaaaatcg
     4201 gaaacaagtt tgtgattaac gaaatcggtc aaaaagctat aaaatcaatg ttttttaccg
     4261 aaaacgaaaa ctcaaatcaa caaccagttg gcgaaaaatc gaaaaccgaa aaccataaaa
     4321 acgccaacca agtttccgaa ttagaactct tttttttcct agaaaaacaa ttaaatcaaa
     4381 aagatataca gctacaagaa aaagacgaac aattaaaaca aatgcaaaaa ttactcgacc
     4441 agcaacaaca actcacctta caagccaatc aacaaatcaa aaaacttcac gaacaactcc
     4501 agctaaccta tgcagaagaa tcttcagaaa aagaacccct ttctgttact gaagaaactc
     4561 aaaaaggaca aaacaaggag aaaaaatggt ggcaattctg gcaataaccc aacaattttt
     4621 attcataaaa attgttgggt tactttcttt ttttgctttt acaagcatag cgacatgatc
     4681 tcacgtcgct attttttaaa gagcataagg aaacgcggta tcactttctt acgaaaggtg
     4741 ctaggtaggc tgtgcctacc acgtttctaa gaaaaaaatt tgctatcact ttttcgccat
     4801 tgtggctagc ttatgtatag tatttcggta aaaaacagct atacaaatac tatatttgta
     4861 tgatatacat aaattataca cacataagaa aggacgtttt ctatggacat tttagttcga
     4921 aatatcaatc caaaaattat tacaagagta gataaacgtt gtcaggaact tacaaccaaa
     4981 acaggagaaa aatggagtcg aaataaatat ttaaaagtgc taatcgaaag tgattttgac
     5041 cgtcaactta tgaattacaa aaaagagcaa ttcgatttat tactcgaaaa atttatcgat
     5101 attcaaacaa aaaatactga aacattgaac gactatgttc atacaaacaa ccaactcatt
     5161 gaaacactta tcggaggaat ataacatgag aaaaacttct gttcaaaaac acgttaccct
     5221 ttatcccagt cacattgacg ttttagattc catcatcgaa aaaaatccag atatcaataa
     5281 ctactcggaa gccattcgct ttttatgtat gagttatgaa cctgatacca atacaacaac
     5341 taccagtaac caagccaaac taaatgcgat gggaaaagaa atttctatca tgaccgaaat
     5401 tatcgcagaa tttgctgatt tgtatttaaa agatacaggc gttcttatcg gtacaaactc
     5461 gaaagtatat caagaagtaa aagaaaaaat tgaaaaacag ctaaatccct cccaacgaaa
     5521 tcaaccaaag aatcgtcaaa aagaaacgag tcaaacattc acttctaaaa atttcgaccc
     5581 aaccaacttt ctaaaaagat aaaaaaataa accaggaaat ttttaatttc ctggtttatt
     5641 ttctagagag cggtcttcca ataagatttg caaatcgatc ccaatttgcg taaaaaaaaa
     5701 gctgctcgta cgagcagcta aacaagaaaa agtcagcttg ttttaagggt aaaataagtg
     5761 taacaaattt tgcgaatgca acgatctttt ttattatacg caaacaatc
//
LOCUS       DACGDM010000129         5790 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.137, whole genome shotgun sequence.
ACCESSION   DACGDM010000129 DACGDM010000000
VERSION     DACGDM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.137"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(99..1229)
                     /locus_tag="IXR05_002638"
     CDS             complement(99..1229)
                     /locus_tag="IXR05_002638"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAQ4261087.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1877..3079)
                     /locus_tag="IXR05_002639"
     CDS             complement(1877..3079)
                     /locus_tag="IXR05_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4261088.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="IXR05_002640"
     CDS             complement(3139..3342)
                     /locus_tag="IXR05_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4261089.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="IXR05_002641"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="IXR05_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4879..5691
                     /locus_tag="IXR05_002642"
     CDS             4879..5691
                     /locus_tag="IXR05_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261090.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1717 a         1189 c          921 g         1963 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta
//
LOCUS       DACGDM010000130         5765 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.138, whole genome shotgun sequence.
ACCESSION   DACGDM010000130 DACGDM010000000
VERSION     DACGDM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.138"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            63..1574
                     /gene="gadC"
                     /locus_tag="IXR05_002643"
     CDS             63..1574
                     /gene="gadC"
                     /locus_tag="IXR05_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HAQ4261091.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            1587..2987
                     /locus_tag="IXR05_002644"
     CDS             1587..2987
                     /locus_tag="IXR05_002644"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003134257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HAQ4261092.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(3152..4592)
                     /locus_tag="IXR05_002645"
                     /pseudo
     CDS             complement(3152..4592)
                     /locus_tag="IXR05_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            4985..5578
                     /locus_tag="IXR05_002646"
                     /pseudo
     CDS             4985..5578
                     /locus_tag="IXR05_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
     gene            complement(5562..>5765)
                     /locus_tag="IXR05_002647"
     CDS             complement(5562..>5765)
                     /locus_tag="IXR05_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4261093.1"
                     /translation="KVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGY
                     RNQRLAQRILDNELGCANASEAV"
BASE COUNT         1820 a          953 c         1102 g         1890 t
ORIGIN      
        1 ataagcgatt ttccataacc ttggtaggaa tgacaaatta aataggaaag ggaagtaata
       61 atatgaataa aaaaaagtta tctctattcg gtttttttgc cctgacagct tccatggttt
      121 tgactgttta tgagtatccg acctttgcaa catcacaatt acatttggtt ttctttcttc
      181 ttttgggagg tattttatgg tttctaccag ttgctttatg tgctgcagaa atggcaacag
      241 ttgaaggatg gaaagatggt gggattttca gttgggttag tcaaacttta ggagaacgtt
      301 ttggttttgc agctattttt ttccaatggt ttcaaattac agtaggtttt attacaatga
      361 tctacttcat actaggagcg ctgtcgtatg taattaattt tccagagctt aatacagatc
      421 catttatcaa gtttattggt gtattagtca ttttctgggt actgactttt tcacagttgg
      481 gcgggaccaa tcgtaccgct aaaattgcta aagcaggatt tgtcattgga attgttattc
      541 cttcgatcat tctctttggt ttagcagcag cctactttat cggcggtaat ccgattcaaa
      601 tggctattaa tgcgaaagct tttattcctg acttttctca gctttcaact ttagtagtat
      661 ttgtatcttt tatattggct tatatgggcg tagaagcttc agcatcacat attaatgagc
      721 tggaaaatcc ccaaagaaac tacccattgg caatgttttt actagtgatt ttggccatcg
      781 ccttagatgc aatcggcggt ttctcagtag cagcggttat tccacaacat gacttgtctc
      841 tcagtgctgg tgtaatccaa acatttgaaa cgcttatttt acattttaac agtcatttac
      901 attggttggt aaaagtgatt gctctcatga ttgcctgtgg cgttatgggt gaagttagtt
      961 cttgggtagt tggtccatca cgagggatgt ttgcagctgc tcagcgaggt ctgttaccag
     1021 ttttcttccg gaaaactaat aaacaagacg ttccagttcc gttgattatg atacaaggaa
     1081 ttatcgttac tatttgggca gcagtcttaa cttttggtgg aggaggcaac aatttatcat
     1141 tcttagtagc aatctcctta actgttgtca tttatctcgt aggatattta ctatttttcc
     1201 taggttactt tgtattagtt tttaagaaaa aagacttaaa acgaacttac aatgtaccag
     1261 gaaaaactgt tggcaaaacg attatcggtg gaattggttt tattttatca gtgttcgcat
     1321 tgcttatctc ttttgtacca ccagcttcaa ttgcagctag tgagcaccga acataccaaa
     1381 tcatactact tattagcttt gtagtgactg ttcttttacc ttttatcatt tatgaagtac
     1441 atgataaaag tgctcacaca actattgagg aacctactca cgtgaaagct gaagacgtta
     1501 atcccgctgt ttatccagct gctagaggag agcaccacgt tacaaaaaat gatgaacata
     1561 ttttaaaaca ttaggaggaa ttcattatgt tatacggaaa agataatcaa gaagaaaaaa
     1621 actatttgga accaattttt ggctctgcaa gtgaggatgt tgacttgcct aaatataagt
     1681 taaacaaaga atccattgaa ccacgaattg cttatcaatt agtacaagac gagatgttgg
     1741 atgaaggaaa tgcgcgatta aacttagcta ctttttgtca aacgtatatg gaacctgaag
     1801 cagtgaaatt gatgacccaa acgttagaaa aaaatgcaat tgataaatca gaatacccac
     1861 gaacaacgga aattgaaaac cgctgtgtaa atatgattgc tgatttatgg catgctccaa
     1921 ataatgaaaa attcatggga acttcaacga tcggctcttc agaagcctgc atgctgggtg
     1981 gtatggccat gaaatttgct tggcgtaaac gtgctgaaaa attaggtctt gatattcaag
     2041 caaaaaaacc taacctggtg atctcttctg gttaccaagt ttgttgggaa aaattctgtg
     2101 tatattggga tgtggaactg agagaagtcc caatggatga aaaacatatg tcaattaatc
     2161 tagatactgt catggattat gtggatgagt acacaattgg tattgtaggt attatgggta
     2221 ttacttacac tggtcgttat gatgatatca agggtctgaa tgatttagtt gaagctcaca
     2281 ataaacaaac tgactataaa gtatacattc atgttgacgc tgcatcgggt ggcttttatg
     2341 caccatttac tgaacctgat ctagtttggg attttcaatt gaaaaatgtt atctcaatta
     2401 attcttcagg tcacaaatat ggtttggtat atccaggtgt gggttgggtc ttatggcgtg
     2461 accaacaata cttaccagaa gaattagtat ttaaagttag ttacttaggt ggagaaatgc
     2521 caactatggc tatcaacttc tctcatagtg cagcacaact aattgggcaa tactacaact
     2581 ttgtacgcta tggctttgat ggttatcgtg atattcacca aagaactcat gatgttgctg
     2641 tttatttagc caaagagatc gaaaaaactg gtatttttga aatcattaat gatggatcag
     2701 aattgccagt tgtgtgctat aagctgaaag aagatcccaa tcgcgaatgg acactatatg
     2761 atttatctga tcgtctgtta atgaagggat ggcaagtccc agcctaccca ttacctaaag
     2821 acttggatca attaattatt caacgcttag ttgttcgagc agactttgga atgaacatgg
     2881 ctggtgatta tgtacaagat atgaaccaag caattgaaga gttgaataaa gctcatattg
     2941 tttatcataa aaaacaggat gtgaaaacgt acggctttac tcactaaaat tcttcagaga
     3001 aatataaaag aagttaatta actaataaaa ggagttgtga ttaccacaca gctccttaaa
     3061 tctatttgaa taaatatatg atattcattt gttacactct caatcttagc tgttgttcta
     3121 ttcatcatta ctcttattgt aagtagttca gtcaaatttg cttgttcaat tgatcgataa
     3181 cagtatgaat tgtttgaaaa gtaatcggat atataattgt tttctcacta cctaagcctt
     3241 cttggtataa agaactatcg caaagtataa tccgctgagt acaaaagaaa gtgtcgtcta
     3301 ctatttctct aagttgttta caaatgatat tactaataga aaagtgttct cccaaaatgt
     3361 cttctaactg ttgtcgatag tataaatacc taaagtctga cggagctact atgaacactt
     3421 caattggaga tttccgttta tgctcattta aaagacttaa actaatggtt agtttacgaa
     3481 tagaattctc attccaacgc agaaataaat tgttttgttt tcgccattgt tcaagaattt
     3541 catgaacttc taagtacaaa gcgcgttgct cttcatttaa caagtaagtc ttatcaggtt
     3601 gaaatatctg aatatcagcc caaagtgagc ggataaacgg gagaagtgct ttatcaaaaa
     3661 gtatctgatt ttcttcagat atattcagag ataagataag tttttgactg agctcaatca
     3721 ccaaagggtt atctgctaca tggttttgat aaacaacgtt caagtctttt tgtaacaatt
     3781 caaagttatc gcatagataa tttctagagt tgaatagaaa gtagatataa aggcattcat
     3841 cttcgtcatg acataaagag aaagaaagtt gctctaatcc tttctgtatt agctgaaaca
     3901 agggagtatg tcgggcaact cttttttctt cctgactaaa atatattggg ttagtcttag
     3961 atctctgcaa accgatagcg atacctaata aaataaattg tttttcaact gtagggtaac
     4021 ttcttgaaaa aaaatgtttt tctacataat caatcaattg ttgaccgctt tgaataattg
     4081 atttatttag ctggatcaac tctgtccgat ttgtctcata gattatcgtt agtaacaaac
     4141 ttcgataatc cttttcagga atttcaaaat ggccatcagc atttaagtac tgcatttgtt
     4201 taaaaaaatt aatcaactca tttcgtaagt tgtaaacttt gcttaacgaa atgaaggtag
     4261 tatcagctat attactccaa ttgtgttccc ctgataaata atgtcctagt acattgaaaa
     4321 agtcagagcg ctgatagatg agttgagtga gtgccaacct cgaaaacgaa gagtcgaatg
     4381 cgactgtaaa gctacttcta gatttctcca ctgaaataat ttgctgatgg agtatgtcgg
     4441 taatgcattc caagtcgtta gtgacagaca gtgagtgggc aaacgttcaa ttgatctgct
     4501 atttcgcgaa tctgaatggt ccctttttcg tgtaattgct cacaaatgta aacttgacga
     4561 aaaatacttt tctccagata ggtttccaac atagtactcc tcctagtcat tttatacata
     4621 actattataa ctctaccaat cggaatagtc ctgtaatata ttgaatcaaa aatataaatt
     4681 ataaaataat tagatggggt atttggttta agtatccctt atatagtaat aaatttatag
     4741 gtgtgattct cgaattaata cccgaaaatg tgagagaatt tttatggatt ttttaggata
     4801 caaattaatt atttttgctt ttatcctgat taccagtcca gtactgtcgg tatcccattt
     4861 tgcagcaaaa tcatgttgat aaagtgacaa gaagactgat gagatatatt atccaaattg
     4921 agaagataat taatcggatt cttgagtata ccctactttt taagaaagta gggtatacaa
     4981 gcgtatgaat aaagacataa ctttccctgt gatggacgtt cggcttgttc caattaccaa
     5041 aatacaggcg aacgattata atcccaatcg agtagcgtct ccggaaatga acttattgga
     5101 gctttctatc attgaagatg gctttactca accattagtt tgttattaca aggaaaaaga
     5161 agagaagtat atcttggttg atgtgcttca taggtatcgt gttgctaagg aaagactcaa
     5221 cttaaaagtt gtaccggtaa cagttattga taaacccata taagaacgta tggcttcaac
     5281 aattcgacac aatcgtgcaa gagggaccca tgaaataaga ggaatggaaa ttgtcatcca
     5341 aagattagta aaaaatggat ggtcagacaa gagaatatcc aaagaattag gcatggacat
     5401 tgaagaaatt tttcgcttta agcaagtgtc tggtggaatg gcaacagttt ttttgacaaa
     5461 ttttataagg tgcagaactt ctttccgtat gctattccga ttgtccttga caatgagcct
     5521 cctcggatgt gacgatcttc ggcaggagct aacagttaaa gttagactgc ctcgctagcg
     5581 ttagcacatc cgagctcatt atcaaggatt cgctgcgcca atctctggtt acggtaacca
     5641 accggtgtct cgtagccaag tgtaccgtgc aaccgaaggt ggttccacca atttacatag
     5701 tcaaataact ccaaatccaa ttgttgtaag gtttcaaatg tgtattgata gacaaattct
     5761 acttt
//
LOCUS       DACGDM010000131         5621 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.139, whole genome shotgun sequence.
ACCESSION   DACGDM010000131 DACGDM010000000
VERSION     DACGDM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.139"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(69..290)
                     /locus_tag="IXR05_002648"
     CDS             complement(69..290)
                     /locus_tag="IXR05_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261094.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            complement(287..577)
                     /locus_tag="IXR05_002649"
     CDS             complement(287..577)
                     /locus_tag="IXR05_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261095.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            complement(574..1758)
                     /locus_tag="IXR05_002650"
     CDS             complement(574..1758)
                     /locus_tag="IXR05_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4261096.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            complement(1940..3343)
                     /locus_tag="IXR05_002651"
     CDS             complement(1940..3343)
                     /locus_tag="IXR05_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAQ4261097.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            complement(3365..4138)
                     /locus_tag="IXR05_002652"
     CDS             complement(3365..4138)
                     /locus_tag="IXR05_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261098.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            complement(4148..4525)
                     /locus_tag="IXR05_002653"
     CDS             complement(4148..4525)
                     /locus_tag="IXR05_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4261099.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            complement(4546..4860)
                     /locus_tag="IXR05_002654"
     CDS             complement(4546..4860)
                     /locus_tag="IXR05_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018705633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4261100.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            complement(5060..>5621)
                     /locus_tag="IXR05_002655"
     CDS             complement(5060..>5621)
                     /locus_tag="IXR05_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4261101.1"
                     /translation="LKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTK
                     HIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTA
                     HKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSE
                     VGYFTSKGDLLYPTQLLDKIEFDYNI"
BASE COUNT         1671 a         1106 c          941 g         1903 t
ORIGIN      
        1 tgtaaacata ttcataaatc ctttcataac aaaatatata cttcctattt tatcatgaaa
       61 aatatctgtt aagcaccaat gattcggtta aataagttta ataacacatc tttcacgcca
      121 gctgcattga acacaagtcc gacggcgatt agagcaataa tcaagaagcc aatgagtttt
      181 gaaaattctc gtttaaaacc taaaaacagt ccaatgacaa caatcgctaa caataccaat
      241 gactgtgcat tatccaagaa ccagttgtac aaattctgcc caaaattcat gtgattgtcc
      301 tcctttcctt aagatatttt tctcgataat agatatagct ttttacacgc cttaataatt
      361 gaaaaggggt taaatgctct ccatagacgg ttactcgatt ggtataatta ttataaaatc
      421 tcaccttgta aaaatcatag gtatagatgg tatcaccagc ttgccgtttt ccctcaataa
      481 tgagagacgt atatttccct gtattttgta tatacgcttg aaactcaatg ccacactgaa
      541 accctaactt ctttaattct tttgttaaaa ggctcatgta atcaaatcct ccatggctag
      601 atgttgttgt tcaattaatt tctcatgttt ttctgtcagt ttggcttcct gaatcatggt
      661 ggagataatg gttgtaccgt tgagaacatc taaaatgctt gcgattttta atgtaggggc
      721 gacttgatga tgtaaccagt tcaatgttcg ttcaaaagaa taaggctctg gctgtgtggt
      781 taggcgtaat gctccacgat ttttaccgat aaaccattcc caacgttcat tagttttcca
      841 atcactccga cgtttagtgt cgtctttatc tgcaaagcgg atatagcgat tgataatttc
      901 aaaggctgtt ttttccgcct gttgatgtgc caataaatct ttcatggctt gggtggctcg
      961 gtcatttttt aaccgaattt caaaccgatt ctttacttct gcgtcttcta agggaacatc
     1021 atttttcacg tattgctcat aatctttctc atatatacag aaatagactt cactttttaa
     1081 tgagccaata taaagtgtgt ttcccatgta tggtttttca tcacggtgaa ccaattcacc
     1141 actgcgataa tttttaaagc ttcgaaagac ggaaatgcat tcttcctgtt tacatttctt
     1201 tgccaaatct ggaatattca aaatccctgt tttatcgttg atagctaaat ccaagcgttt
     1261 gaaaatacct ttatgttcca tgcaatcttg aaagaaatca taccagctcc gatgttgagc
     1321 caatagaaag ttttcaaatt gccgacagcc ttttcctttc agttctaata aaacaccttt
     1381 acttacatca tgagagacta ggacaacaat atcaccgaaa cgatagtgtt cgggataaga
     1441 ataatagcca aagtcttcgt gtagcatata atccatattc aaacgtaaaa cctcaccgat
     1501 aatttgagcc acatcattgg tagggaatcg aatccgtaca tagtcgaata acatctccaa
     1561 tgggttatcg ggattgaagc gttccaaagc gttcagtaaa tcttctttca cctgttgagt
     1621 agggactgcc ttgcctgttt caatatccga taggtaaggt ctggtaatat gagaagcaac
     1681 cgccagttta ttttgagaaa cgccataagc cagtcgcttt tctttcaatt ccttaatcca
     1741 aattttttcg ttttccattc gcaaacctcc aatctaaaaa agatgtaaac tatgaccctt
     1801 gagtttacac ctttcatatt ttccgcaatc ctttgtacca tcaacattgg ttgatgagaa
     1861 ttgcctgttt tcagttgtat ttgtgccccc ctgttagata gagggggcta aaggattggc
     1921 gtggctaacg ccacaccaat caaagcaagt ctgaacctgt acctttcact tcgtgcggta
     1981 caggctcaga ttgctttttt tgaatgactt ttcctatttc tcctaagaaa tcgtaccttt
     2041 ttggtacaag gggtgtataa aactcactaa tcacactttt tcctgtatcc acgtaacctc
     2101 ttcccttgat gggttttaag aaaaattgtt tttgtgtatc gcttccgaac atcataccaa
     2161 agcccatttc agacatacga cccaaagcca cacggaagtt aaagttgtcc cgaatcccat
     2221 cactaaaata ttttgcgtct ggacgttgac aggcaagaat taaaaagaag cctgcttgtc
     2281 gtcctaacat tacaatttgt ttgagtttat gaataacggt ggtactttca cgacctagca
     2341 tatccatcat tgccacatat tcatcaaaaa taagaaaatt ggcagacaaa ccaagataag
     2401 cataattttc tcctgtttta tagttagggt gttgtttcat ggtttcactg cgatcaatca
     2461 tatcttcgta aaattgattg atacatgcca acatatcttc tttacggtaa tagacattat
     2521 tcatgaccgc ccctaagtct gccaaatcag catttttagg gtcaagaata taaagctttg
     2581 catttgtatg caggagagat tcaatcaatg tgagaataaa ataggatttt ccactaccag
     2641 tgcccccagc aattaacatg tgagggagag aatcgaactc ccaatagacc gattccatca
     2701 atttgacacg tccatcttga gctaccacgt cttcaatgcc aattcgattg ccaatagtat
     2761 cataaagtag gacatactct acataagaat ctttcaacgt tttttccact aattcacaat
     2821 acaatcctgt ttctagtttg ttttctaggt gcaaaagctg atcttgatat ttccctaagg
     2881 tgatttctac atgaatatgg attagtccat ctttcattcg ataatatatt ttaggaaaat
     2941 ggcggattcg ttgtttggtt ttcttgctgg gtaaatcttt aaagaatccc tctgattgag
     3001 tttcttcggc ttcataccaa tgattttcta aaatcatacg agctaacttt tgacggtgct
     3061 ctaactgttt tatagaatct atacgatagt gataataaag ccagctgata agtccgcata
     3121 caaaaagagc agtgagaata ctgctccaaa agtatggcgt atgaagttga tagaaaaatg
     3181 tatctaactg aactgcttgc cagttcaccg attgtaacgc tctccaatga aaagggagta
     3241 ggacgactag aaaaactacc agcaatgaaa ttagtacaaa atgatagacc aagtgcttat
     3301 cgttggcttt gattcgctct cctctgtcat gaagcaatgg cataaaaatc ctcctttcca
     3361 cctatcaaaa taattgtgta ttgtagatac gagcctgttt atcaaaagtt ggttgagaaa
     3421 tggcttcata tttctgataa gcgattcgct tttcaaagcg taaatttttt tctttcggat
     3481 aataatgacg tcgatagaga gtgtgtccta acagtttttt cgcttctttt gtcaacggat
     3541 agagatagcg aaacatgcgt ccattgattt tctcaatccc tttgtattcg caaaatgcct
     3601 gggaaagcca atgctttttc tctacctgtt caaagcgagc attttcctct aataaaaggc
     3661 gagcacttcg agggtgtatc ttttcccatg actgcttatc acgatagaca cttgtcttga
     3721 aatacccgca gtaaaagaag ttggacgctt gatagacata gccacatttt ccctcaattc
     3781 catctgccag tgtatataaa aaatgacagt ccgtatgttc tttcaaccac ttaattagag
     3841 ctgaaagagc ttgactgcca aaataattgg tttgattcat ttctggaaga aaacacatct
     3901 ttccaatttc taaataatct gtggtttgaa gggaactgtc gggaaagagt ttgcgtatgg
     3961 tttgtagggg ttgcgtaccc cagcctaatt ccacaacgcc taataatttt tcttctgaaa
     4021 aaatccctag aaagtattta cacaatctag ggagtatctt tgaataatgg tattgccgaa
     4081 taaaagaaat ggcttcatcc ttcggaattt ctttcaaaat caatggtgtg tttgtcataa
     4141 gcaacaccta tttttcactt tcggacgctt cttttttata tttctgatga ggttttgtct
     4201 gtccttttaa tacaagatcg tctgctttca cgtaccaatc aacgtctgcc cctcgaaaag
     4261 tagccgtcgc tacggtatct gccacaggat tgattaattc cacttctgcg ttgtagtcaa
     4321 attctttcaa aggaacagaa gcggggatac tgacttgtat catgcgtcct tgtccttttg
     4381 attttaagtc ataggtacgt tctttaattt cttcggaaac cgtaccatct tcattctgga
     4441 tacgaacctc acgacgcaag gcggaaaatt tcaatgtgcc aaatgtctgg tctttttcaa
     4501 tcacaatacc ttctgctaat ctcatatttt ttcacctttc ctttcttatg ctttcaccat
     4561 atcgtctgcg tgcataatgt aattggtaaa tcctcgattg ccaattttat aaccttctgc
     4621 ggtaatatgt gggttgatga gtttgacttt ttcgtcggat tcaaaatgtt tctcgccagc
     4681 ttcggaggga agaatgacaa caatatcatc tgctcgttga atcgttgagt ataaattgta
     4741 actacgagag agaatggttg gtctgccatt tattcgacgt tgttcaatgt tcccttcacc
     4801 agcatattct aattgtccaa atgttttttc catattggga atgacatatt taagttccat
     4861 atttttacct atcctttctg tttttatgtt tgaatgaatc ttatttgtgt gatggtttta
     4921 aaggggggag agcgaccttt tgattcttga ttttttattt tcataagttc acttcctttc
     4981 aaaattgggt aaaaaaatag acgctccgta ctgagcgtcc gattcctact atatttaaaa
     5041 caacgactac ctaggtattt taaatattat aatcaaattc tattttatct aataattgag
     5101 tgggataaag caagtctcct ttactcgtaa aataacccac ctctgagaaa agaaataaat
     5161 tattttttgc tcttgaacaa attacgtata gtagttttct cgctgaacta attcctttat
     5221 cagaaacatt aaaaatttca ttccaatgag gaattttccc gtttagaaga ttaatagcga
     5281 taacagtatc atactcattt cctttaactt tatgtgctgt agtaagtgtg ataccatctc
     5341 gagatttaaa catcttctta aaactagata cactactaga taatgaatta ttttttatcc
     5401 gatcttctac ttcgttaata aaaaatagat agtgcttaaa aatagacggg taatttttct
     5461 cgtcaatatt aagattaaca aatatatgtt tggtaacaaa tttgtataaa tcaacaccgt
     5521 tgtcgtctcc actatacatt cttttcacac tgtttattag ctgtaataaa tctaagtcaa
     5581 taaaataatc tttaacttct attccaaatt cattttttaa t
//
LOCUS       DACGDM010000132         5592 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.140, whole genome shotgun sequence.
ACCESSION   DACGDM010000132 DACGDM010000000
VERSION     DACGDM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.140"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(59..2008)
                     /locus_tag="IXR05_002656"
     CDS             complement(59..2008)
                     /locus_tag="IXR05_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAQ4261102.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(2050..3108)
                     /locus_tag="IXR05_002657"
     CDS             complement(2050..3108)
                     /locus_tag="IXR05_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAQ4261103.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(3227..3682)
                     /locus_tag="IXR05_002658"
     CDS             complement(3227..3682)
                     /locus_tag="IXR05_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261104.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(4266..5069)
                     /locus_tag="IXR05_002659"
     CDS             complement(4266..5069)
                     /locus_tag="IXR05_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4261105.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
BASE COUNT         1650 a         1103 c          776 g         2063 t
ORIGIN      
        1 cttacgaccc atcgttttat tctaaggttt tgtagtaaat atttcttgaa tttcatagct
       61 acgcccctcc aatcgaaaat acaatcttgt tttctttact ttcagcaacg gaaggctttg
      121 caataatttc agcattagaa tcaccttttc cttcaaacgc tccggcttca ctcaacttaa
      181 catcgaatat ttttgcgttt ggataagtaa ttattgcttc agtaatcgct tcttcaaact
      241 cagattcaac taaatgcaag atattccttg caccccctga tttagaatcc tcttgtgaag
      301 ccatgtcaaa aactaagtgc atggagagat cgtctgcata aaaattttga ccatatactc
      361 tttctttcct aggtggaaga cgtaaatcta tatttaaatg ttttcgtact aattcagcac
      421 tcttcaacat ttcattataa gcaatttcca gaagagtttg ttcggataaa gcccaaaatg
      481 gaactattcg tccaaatcgg ttaataactt caggctttag accttcacca atcaaggctt
      541 gtttgatccc tgatgcgact tttcggtatt ctctttttag ttcagtgctg tattcattag
      601 aattttcctt gtttgtaaca cgagatagtg agctatatcg gtttaacgaa tcgaacatct
      661 ccgcacctgc atttgttgtc gcaaataaaa ttgtatttga caatgaaacg gtgtcgtgaa
      721 cttctcgatc atcccatcct ctttcagtaa aacttatcct accttcatct aaaattgata
      781 aaaaggcatc gagtgtttct acaccagctt tctcatattc atcacacaca ataatcgcag
      841 aaggatcatg ccttacatga gtacctataa gtcgtctaaa acgcattgca tcatctttgg
      901 ttttgtagtc cggcatatta actaagagaa ctttattttc atcgccataa agtcctcttg
      961 ccacggcttt agccattgca gttttaccga cccctgttga tcctgtaaac agagcagttg
     1021 cttttggttg ctttcgacct ttaaaacgat caaatccaag cttcatacgt ttaaacaaca
     1081 ttgttatagt ataaactgct aacggttgtc cttttatgga ctttaattcc tcttgaagtt
     1141 tttccatatc aaaatcagaa tctagctgaa tattatactt accaaatatt tgcaatagac
     1201 tttctcgatt ataagcattt ccgtctactc gatcttttgc aatcaaatcc tccattacag
     1261 caattgattt agccggttcg gacaaatcct cacgataaag tttgtttgct tgtacgattt
     1321 cttgaagtaa ttcatcagga atcctttgcg ataatctaaa agaagcctga ggatcatctt
     1381 taacagagga tgtatttagc cattgtctca aaatatcgac gacaacatcg ctttttagtt
     1441 cattcaattc taacggttgt agccgtctcc ctaaggcatc atctcttttg atatagtttt
     1501 catattcttt tcttgtagta gcggtaatca tttgaagtga ttcatttgct aacggttctt
     1561 ttagcgaatc acccccaatt ttattgccac tcccaaaaga gctaacaact ttatgaaact
     1621 cgtcaatgaa gaggacaaat tcattatctt tgtcctcagc ttttaaaatt cgctcatatt
     1681 ctttcaatct tggaattaat gtttctaaac gtgtttggag gacatcatct cccccaacac
     1741 gcaattgtcc gattgataat ttatatactt gtactttctt tccatcttgt cgctgtcttt
     1801 cagcccattc acttgcaagt gctgttttac ctgttccggc ttcacctaac aagatagctt
     1861 gcggtgtttc cggtctattc aagatcagtg acaactcatg gagttcgtca tcacgtccca
     1921 ctaacttatg ttttggtggt ttcattggtg tgagagcatg attaaattcg gtttgaatat
     1981 tcttaaaaaa ctcggtacta ttttccatct gtttgtgttc acttcctcta aaataagaat
     2041 aatttacttc tagtcagtca aagttaggta cttaaatgtc gtcttcatgt ctccaaaaga
     2101 atctttgtta aagtcagcat ttttgtattg atcaatcaat ttttgtgtat cattgattgc
     2161 tttaatttcg gtctccattc gactgtctag ttgacgaata ctttcttgcg aatctttatc
     2221 gtcaggattt tgttgtaaac gttccagata ctcagctttt gtggcttcaa ttttcttgat
     2281 gttagtattt gaagcattta actgatcttc tagcttattt acaacattat tcttacttgt
     2341 aactgctaca acttttgaat aatcaatatc gccatctttg gtaagaaagc ttccttgata
     2401 gacattagtt gaatctgaat atggatttat tctgaaattg atattatcag gagtattaac
     2461 aggttttgct tttttcccaa aagaaattac tccttcatta ttaacatcat tcatagaata
     2521 ttgagaaagt gcttttgtaa ctgaatctgc ttcattcaca ttgactttgg tatcatcgtc
     2581 agctgtatca tcaccagaaa ttagtgatac ttggtttgca ataaaaactt gataagctct
     2641 ttcctctaat ttacctttta ggaataagaa agcatcccca tcagtactta acatcccata
     2701 gctcatttca agcttcttag gacgatcttt ttcttttgtt gccatatata agttatagtt
     2761 ttttccttgc gtagataaca actttctagc gttttgggag taaccaagtt ttactactgt
     2821 tacatctcta ttttgatctg tccacacatc tgaaatagtg atttctgctc ctgatcgagc
     2881 aaactccaat gaagacccta taggtgttgt attgttcacg agataataat tatagtttcc
     2941 taattgataa atgtagctac ccaagcctgt taataaaaaa agcactccta gaaaagttgc
     3001 aagcataatg cgtaatccgt gacgtgttct cttatcctta tcaccaagca accctccaat
     3061 aatactgtat tgatctttgg tagatgttga attgacgttt ttttccatca gtttgtctgc
     3121 cccctttcat aaaagagcaa acaatcagac gttttttcgg taattctagg ttcgggattt
     3181 tgaatcattt cggtatattc ttccccatta atatttaaca caaaaattat cttcctttct
     3241 tcgttccttt cttttgctct ttattttcca aataatcaat gatttttgct attgtaccaa
     3301 gatagtaatt cccctcagct ttgttttttc ggattttgct aaccattgga gtaggtacaa
     3361 tctcttcatc tctcaattca ctgaaagatt ttttacctag atattttcca ataacagatt
     3421 ttaaaaaacg ttcaaaatct ttctcgtaag ttgttttctt gccttttagt tcatggttca
     3481 tattgtcaac gacttttgcg gtttcaataa ttgttttagt tctcagctta ataatttcat
     3541 ctggaatttt caatcctcgt aatttcatcg ttgtactaac tggtaaccca tgctttactg
     3601 catcagcaat actaaaactt tttagatcat ctagtaagct ctccatatag ttaacaaatt
     3661 catgccaatt aatagcattc attgtctcac cccttcattt ttttaaaatg aggttcgggc
     3721 gtaacacatt tatgttatta taatatcata ataacataaa taaatcaatc agcaaattta
     3781 gatatccctt aaagtatcag caattattca acaagatatt tattttagct atttcagtca
     3841 tcataaaaga ctaattagca ataaaataac taatattatc catttatcag acgaaaagaa
     3901 aaaacttatc taattactct atattaactt ttaacaaata gttgacttgt ccaaaaatgt
     3961 taccttcaat ctcacaaaga tattaagatg tttcctacca aaactgatat caccggactt
     4021 tttattctgt gttgtccaaa agtgttacct ttagtcgatc aacaaattaa aaaaaattgt
     4081 ttttttcttg acttgtccaa aagtgttacc catagttgtt aaaatttgta tagattagcc
     4141 attctttcga atattattta gactgaaact tgcttacaaa aaaacttctt gcatttattg
     4201 tccaaaagtg ttacccatac ttttttaaag aagcaggttg tattaaaatt acaacctgct
     4261 tcttctcaat cttcttctaa ccaattatgc attgaaatgg ttggcaagtt tgattctggc
     4321 tcactaaaag tgaatctgag ccgatcaact cttcttcctt tctttgcata gattttttca
     4381 taatcaaaag tttcaaatac ctgtattccg ttttcatcag gagctaaaaa ttcttctttc
     4441 gcctgctcta gtattctttt gtcaatattt gtcattctat aacttgaagg tatacttaat
     4501 gctcttctaa aatcttcaac tttgactacc caataaccat ttcgccactc tttatttctg
     4561 tattgcatga gatgacgata caattctttt gtgtagctac ttcttagttt tgtaaaatta
     4621 tcaagttcaa aacgagtaaa gtttttgcca attgagttta agataaattc aaattcctca
     4681 tttgccttaa ttgtaactgt ttccttctgt ttatctatcc ggaatttttg aaaaagccac
     4741 agctgttcat agacgtctga atcttcaaaa cggtaggtta aagtacctag tttgtcactc
     4801 aaagctttta acacagaata aaaactgtcc ttttctcttc tgtcgtattt gaccaaataa
     4861 cgaaagaggt tgaaatcaaa agttacttct gctgttcctt gacgtttcat ttttgataaa
     4921 atagcccaaa acacatccat ttcaacaggc ttaaatcctc gcaaagctgt tgtattcaga
     4981 ccattgttat aacgcacaat tgcatttgtt tgttctgata ctaaatctac atcactatca
     5041 ataatctttt cggtaacttc ttgagacatt gattactctc caatcttctt tttgcgctcc
     5101 tttaatcatg ttaatctggt actaattaaa ggaaacaatt ttttctgctt gttacctaaa
     5161 ttaaatcaca actaaaggta acagtcaaca aagatttgtt actaatctaa ttttctattt
     5221 tttcgccttc caaatcaaga aaaccgaagg taacgtctta tcctagtgtg atacctcaaa
     5281 tgtccacttt tgttaccttt gctgtccaaa agtgttaccc ttactgtcca cttttgttac
     5341 ctttactgtc caaaagtgtt acctttatac ccctttaata cttactctcc caagagatta
     5401 agcctcccct aacagatata ttaacagata tttaacagat atattaacag atatttaata
     5461 aaggaggatt actcctctct tatttcaaaa tcttaaaaat aaaaaatctt aaaaaaaact
     5521 aacactatct aggagtttat tttgcttgtg taactttgaa taattgaaaa aaaggaaaag
     5581 gaggaagctt ca
//
LOCUS       DACGDM010000133         5350 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.141, whole genome shotgun sequence.
ACCESSION   DACGDM010000133 DACGDM010000000
VERSION     DACGDM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.141"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            109..181
                     /locus_tag="IXR05_002660"
     tRNA            109..181
                     /locus_tag="IXR05_002660"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:142..144,aa:Lys,seq:ctt)
     gene            343..564
                     /locus_tag="IXR05_002661"
     CDS             343..564
                     /locus_tag="IXR05_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261106.1"
                     /translation="MRNEIANITIIRETLQNHTANEISKHTGLNLSTIKKLKSGERSI
                     EKLNLHDAICLTEFGLKNNRKNVEINIWK"
     gene            complement(888..1133)
                     /locus_tag="IXR05_002662"
     CDS             complement(888..1133)
                     /locus_tag="IXR05_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261107.1"
                     /translation="MVDNPKKRQYPLVPLSIIQSALEEDPISIKMILKHYHSYIAKLC
                     LTNGFNEAGQFITYVDEYMLRQLEIKLIEAILKFKIN"
     gene            complement(1127..1528)
                     /locus_tag="IXR05_002663"
     CDS             complement(1127..1528)
                     /locus_tag="IXR05_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4261108.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNETKSIRKRNINITDNEEPLT
                     NSNEGKYSQTHFDEQDVYFLFGMEILISDQKLSAAIDHLSEIRRKVILLYYFAGFNDT
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(1700..3508)
                     /gene="uidA"
                     /locus_tag="IXR05_002664"
     CDS             complement(1700..3508)
                     /gene="uidA"
                     /locus_tag="IXR05_002664"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAQ4261109.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPMVEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVILPKKLLEERLVLRFGSATHEAKVFLNG
                     KLINQHKGGFTPFESEINQFIKDGSNRITVAVNNVIDDSTLPVGILKETIQEDGDIKK
                     ENLVNFDFFNYAGINRPVKLYTTPKDYIKDVTINTKIIDSDANVEFNIDTEWTGEILI
                     AIYDEEAQLIAEAKGKEGVIQLKNPTLWEPLNAYLYSMKVSLINENKVIDTYTEEFGI
                     RSIQVSNGKFLINNKPFYFKGFGKHEDTYINGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHDTWKEIRTENAHKM
                     AIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLKHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGLHDTVPTMFTEEYQVGYYEANHEVIDKCDNFVGEQVWNFADFETSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLKKRWSSIPNFSYKK"
     gene            complement(3536..5302)
                     /locus_tag="IXR05_002665"
     CDS             complement(3536..5302)
                     /locus_tag="IXR05_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAQ4261110.1"
                     /translation="MTIKVDLRKKPYHLDEDAISWIEETIDAMTLEEKIGQLFVNMGS
                     SRDKNYLSSMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQSPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLSTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNLDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYYKG
                     IISEERLRDALRRILGLKAKLGLHKKEKNKILLPKQEAMEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKDLTEKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGISPIDAYCGLKDTFI"
BASE COUNT         1672 a         1017 c          707 g         1954 t
ORIGIN      
        1 ttcaaatatt ttttcataat cttgaaaatc cataaaattc actctcaatt ctgataataa
       61 gtattgcact tttttatttt aggtgttaga ataacaaagt attaatttgg gctgttagct
      121 cagttggtag agcagatgac tcttaatcat cgggtcgcgg gttcgagccc ctcacagccc
      181 attgggtgcc aaacccttaa atacagtgta aacgttggtg cttagcattt agaaaacgta
      241 tatactgtat ttttttgttt tcaaaagaga ctgtagtacc cctttttttc actaaaagcc
      301 cactgtagtc attgatattt ttgataagaa aggaacataa ttatgcgtaa tgaaattgct
      361 aatataacaa taatccgaga aactttacaa aaccatactg caaatgagat ctctaaacat
      421 acaggattaa atttgagtac tataaaaaaa ctaaaaagtg gagaacgttc aatagaaaaa
      481 ctaaatttac atgatgctat ttgcctcact gaatttggtc ttaaaaataa tagaaaaaat
      541 gttgaaatca acatatggaa ataattctta atcagctgct tttgtcaaaa gcacatagga
      601 atttcacctc tctccaagtt tacggcgagc cttacggaag tatcattatc ccaacttcaa
      661 atcatcgctt tttattgact ataaaaatta ttttagaatg tttatcgctc cttctttaca
      721 gtaagaaatc atggcgcaac taaaatatgc tccttgaagt gttaacgtac tgatagaatg
      781 tatttaaatt tcaatgatca ataggttttc tgtttaaaag aatctactaa tcctttaact
      841 attagaagat tcttttaaac agaataagtg gaaaggggac tttttagtta gttaatttta
      901 aattttaaga tcgcttctat caatttaatt tctagctgtc ttagcatata ctcatctaca
      961 taggtaataa attgccccgc ctcattaaat ccatttgtca aacataactt agctatataa
     1021 ctatgataat gtttgagtat catcttgatt gaaattggat cttcttctag agcagattgg
     1081 ataatggata gaggaactaa tggatactgc cgttttttgg ggttgtctac cataagtcat
     1141 accccatttt taattgttca actgccttct ttcgttgata ccagatacca cttgtactca
     1201 tattgaggat tttaccgatt tcagtatcat taaaacctgc aaaataataa agtaggataa
     1261 cctttcttct tatttccgat aaatgatcaa tggctgccga taacttttga tctgaaatta
     1321 atatttccat tccaaataag aaatagacat cttgttcatc aaaatgagtt tgggagtact
     1381 taccttcatt tgaattcgtc aatggttcct cattatctgt tatgttaatg tttcgttttc
     1441 gaatagactt agtttcgttt cgtaatactt ttttacagta ggcatcaaat tgatgttgta
     1501 tagatttctc attgtaattt tgttgcatga taaatatgct ccttttttcc cctttccact
     1561 aatacaacaa tcagaaagcg cctttttttc gaaaaaacta gaaaaaaata tccttcttta
     1621 aacagaaaat ctttttataa aaaaaaggag ttggcaatta agcagccact ccttttttat
     1681 attccttata aaaggtaaat tattttttat aactgaaatt tggtattgat gaccatcgtt
     1741 tctttagata gtgagcaatc attttaggct ttctatctct agtaaagatt cctttcttat
     1801 ttccttgcac tcttaaaatc ccttgacttg tttcaaaatc tgcaaaattc cacacttgtt
     1861 caccaacaaa attgtcacat ttatctatta cttcgtgatt tgcttcgtaa taacccactt
     1921 gatactcttc tgtaaacatt gttggtactg tatcatgaag tccagctact gtatctgctc
     1981 catattctgt aaacattatt ggcgtatcgg gacatctttc catccatcca tctagctctt
     2041 ttttcaacag atattttgca tgttttaggt ctccacctga aacataccaa ccataatagc
     2101 gatttaaaca taaaacatcg acaatatctc ctactttaca aatatctggt gttgacttta
     2161 agtaagtaac gattgttaca ggtctcttct gagggtcaag ttctttagtc aattcaacta
     2221 aaggttcaaa atattcttta gcgccttcag aatccgaatc tggttcattt gcaatagacc
     2281 acattacgac actcggatgg ttcttgtcgc gttctatcaa ttccttaatc gccattttgt
     2341 gagcattttc tgtccgtatt tctttccaag tatcatgttt ttctacgttg tcatctaata
     2401 aagtagccat gaaattcaaa tgtaatccta ctgcaggtac ttcatcaata actacaatac
     2461 cttctcgatc tgctaagcgc ataatttctt ctgaataagg ataatgtgaa gtcctaaatg
     2521 aattagcacc gatccatttc attaaattaa aatctttgat atttactgct tcattcaaac
     2581 cacgaccatt aatatacgtg tcctcatgct tcccaaatcc cttaaagtaa aaaggtttat
     2641 tattaatcaa aaacttccca ttcgaaacct gaatactacg aatgccaaat tcttctgtgt
     2701 acgtatcaat cactttattt tcgttaatta aactaacttt catactatat aagtaagcat
     2761 ttagaggctc ccaaagtgtt gggttcttaa gttgaatcac tccttctttc cccttagctt
     2821 ctgctataag ttgagcttct tcgtcataga ttgctattag aatttctccg gtccattctg
     2881 tatcgatatt aaattctaca tttgcatctg aatcaattat ttttgtatta atagtgacat
     2941 cctttatata gtctttcgga gttgtataca atttaacggg tctattaatg cctgcataat
     3001 tgaaaaagtc aaaattaacc aaattttctt tttttatgtc tccatcttcc tgtatcgttt
     3061 ctttcaaaat ccctacaggt aaagtgctat cgtcaataac attgtttaca gccactgtaa
     3121 ttctgttact tccatctttt ataaactgat taatttctga ttcaaatggc gtaaaccctc
     3181 ctttgtgttg attaatcaat tttccattca aaaatacttt tgcttcatgt gttgcagatc
     3241 caaaacgaag aactaatctt tcttctaata attttttagg aagaatcact tctttttcat
     3301 accacaccca tccaacatga tttctaatgt tctctgtttc aaataaatca ttataagaag
     3361 aaggaactga aattggataa ctctcttttt caaccattgg ttctaaagca agttcttctt
     3421 gtaagtcatc atttgtatct aacttaaatc tccaaagacc gcttaaatca attacttgcc
     3481 tcgtctctgt cataatggga tataacatgt aaatcactcc tatataattt aaatattaaa
     3541 taaatgtatc ctttaaccca caataagcat ctattggact tattccctta aattcagaaa
     3601 ggcccattag tttgtccact aatatttcta aagtttcttg ttttccatca taagtattga
     3661 tataagtttt tacttgaggc acatcagcta aatgaaacgg acactgtaca gatacaaaaa
     3721 ttgttggaat ttcatgaata taaaatggaa tatccggagt acctttactt gctggccaaa
     3781 caattctttg aactgtacct gggttaacat tagctatatt aataatcaag tcatattttt
     3841 cagttaaatc tttgattggt ctcttagcag catatattcc agctatattt ttaatttttt
     3901 cttcttgcga taatcctttc aattcttctt caggtgaaat gtatttttca acttcaaatc
     3961 cttttgctga caaaatctgt ttcaataaat caatggcctg aggtctattt ccagcaacta
     4021 cttcaccaaa cccacctttt accccatgta catctaccag taaaatcctt ttatattttt
     4081 ctggtacaat aggccaaata tcttgtttat ctttaactag tgtaattgct tgatcagcta
     4141 cctctttaaa aattgattta ttttcaatta aaccaatttt ttccatagct tcttgtttcg
     4201 gtaacaaaat tttattcttt tcttttttat gcaaacctag tttagccttt aagcctaaaa
     4261 ttcttcttaa tgcatcacgt aaacgctctt ctgaaataat tcctttgtaa taaccttcca
     4321 tcatataatt aaagtcttca tctggatcat taaaaaatag gaatagatca catccagccg
     4381 caatagaagt gggcaataat tctgaccgtt tcattgcccc agtcattcct aacatatgac
     4441 tagcatcagt aactactaat ccattaaacc cgagttttcc tctaagtaag tcagtgatta
     4501 attcttttga taaagttgca ggaagtaaat cttcatcttt cagatcaaga ttaaaatgtt
     4561 ttgaataagc tggcatatgg atatgacctg ccataattga aggtaatcca gcttctatta
     4621 agcctgagta tacttttcca aaagaattat cccattcttc tgtacttaaa ctattaatac
     4681 taaaagatag atgttgatct cgttcgtcaa taccgtcacc agggaaatgt ttagctgcag
     4741 gcaaaattcc actctcttga atacctttca tataagctaa actaagttct aaaactttat
     4801 cagggctttg tccaaaagat cgactagaaa tgataggatt tctccaattt ctattaatat
     4861 ctacaatagg agcaaaactc cagttacatc caatagccga tgcttcaatt ccagaaactc
     4921 tccctaattc ataagcatat ttcgcatcat ttgttgcacc aatttttact tctacaccaa
     4981 cttcggtacc atctgtacaa gctccgttac cacctgcttc tgtattagca gcaattaata
     5041 aaggaatttt gctttctgtt tgtaggatat agttttgatc atatacctca tcagcagttc
     5101 ctggattata tcgtacagct ccaatatggt actgattgac catactactt aagtaatttt
     5161 tatcacgact agatcccata ttaacaaata attgacctat tttttcttct aaagtcatag
     5221 catcaatcgt ctcttcaatc caagaaatag catcttcatc taaatgatat ggtttttttc
     5281 gtaagtctac ttttatagtc attttctttc tcctctactt attagtaaga tttttccaaa
     5341 aagtatctat
//
LOCUS       DACGDM010000134         5282 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.142, whole genome shotgun sequence.
ACCESSION   DACGDM010000134 DACGDM010000000
VERSION     DACGDM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.142"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(106..1254)
                     /gene="nagA"
                     /locus_tag="IXR05_002666"
     CDS             complement(106..1254)
                     /gene="nagA"
                     /locus_tag="IXR05_002666"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAQ4261111.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1330..2166)
                     /locus_tag="IXR05_002667"
     CDS             complement(1330..2166)
                     /locus_tag="IXR05_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261112.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2350..3567)
                     /locus_tag="IXR05_002668"
     CDS             complement(2350..3567)
                     /locus_tag="IXR05_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4261113.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3950..4033
                     /locus_tag="IXR05_002669"
     tRNA            3950..4033
                     /locus_tag="IXR05_002669"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3984..3986,aa:Leu,seq:gag)
     gene            complement(4273..5271)
                     /locus_tag="IXR05_002670"
     CDS             complement(4273..5271)
                     /locus_tag="IXR05_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261114.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1639 a         1076 c          839 g         1728 t
ORIGIN      
        1 attaaagaaa cttttgaaac ttatgtaaag tgatttttac tagaacacaa aaaaacctta
       61 aaaccaaact taagaagttt agttttaagg ttaacttaaa ttatattatg cgtggaaacg
      121 ttccacgcca tctagataag ttgcttccaa tgtcatatca gggttcaata cgataaagtc
      181 tgcatcgcgt ccttgagcga tttttccaca tgtatcatcg attttacagc tgattgctgg
      241 aatcagacta gccatcatga ctgcttgttc tggtgttgct aatccccagt ctacaacatt
      301 tttaattgct tctttcaatt tcaatatact tccagctaag ttgccagatt ctagacgtgc
      361 tgttccttct tttactacta ctggaaattc gcctaaattg taatttccat caggcatccc
      421 accggccatc atacagtctg taattaatgc gacatgatca tgtcctgctt tttccattag
      481 gattcccgca gcatttggat gtacatgatg gccatcacaa atcaattcag aaaagacatg
      541 ttctaaagat aataacgcac ccaccatacc tggttcgcga tgattcaatc cacgcatacc
      601 attgaaagca tggacaaata cacttgcgcc tgcttcaaca gctttttgcg cttcttctag
      661 tgtagcatta ctgtgtccta gagaaacaac tactccttct tcagtcactt gtttgacaaa
      721 ctcttctaca ccttgacgtt ccggtgctaa agcaattttt ttgattaaac cacctgaagc
      781 ttcttgccat tcatggaaag tatccaaatc aggatccccg aaataacttg ggttttgtgc
      841 ccctttgtgt tcttctgtga agaaaggacc ttcaaaatag attcctttga ttttagctcc
      901 tggtgcttcc tgatacattt tgccgattgt ctcagctaca tcttttaaac gttctttgct
      961 tgacgtcaat gttgttggta aaaatgaagt cactccacaa gataacagac cttcagacat
     1021 cactttgatg ccttctgcat cattatccat tacatcatga ttcatatagc cgtgaatatg
     1081 tgtatctacc aaaccaggag caatccattt gccgctttgg tcaatgatgt tgacttctcc
     1141 ctcaggtagt tctttggtgt attcaccaaa aagtccatcg gtaatttcaa gatagcctgc
     1201 atgtttgaca cctgacgcta aaaagaattt gtcagcatag ataaaagttc tcattctatt
     1261 ctctcccttt gtttttctac ctctaaagta ctcttattta gagaagaagt caagaatggt
     1321 ctacaccatt tacaaatttt ttgaaatttg tttcacagct tgtgctaagc cttcatagaa
     1381 tgctgctctt tctggttctt ctttacgctt gtatattaag cttttaagca caaataaatc
     1441 attgaggtaa tagtagctat tcttctcttg agcccaatag attccttgat tcacctgttc
     1501 taacgcttcg tcgatttcat tttgatggaa taagaaattt ccataattat aaaaaatttg
     1561 cgaaaattca ctttttgatc gttcatcagc tgattgatgc agcagttgga tgcttcgact
     1621 caaatagtag cgtgcttcag ccgtttttcc tgccacacca tatatttttc cgatacaact
     1681 aatcagttgt atttctgtgt cagaaacatg gattctttct ttttggctag agtagcttaa
     1741 tgcttctttc aaataataaa gggactgaga gatattttga cgcaacgtga attcgcaaac
     1801 accgagataa taataatagc gttgaaagtc agttgcttga tacagatttt cagaaatatc
     1861 agaagatttt agtacttgtt ctaacttccg ataatcacgt ttttggaaac aactatccaa
     1921 cagttcaaat aatttatcgt ttgtccgagt agtttttcga gagagattca tcacatgatc
     1981 aatcgttacc cctagccgtt gacaaatctg catcatcacc aatacattcg gcagttcctc
     2041 attattttcg atccgactta atacactttg tgaacaaata tcatgcgaaa gcattttttg
     2101 cgtcattttt tgttcttttc gaatctcttt aatgatcgtt ccaaaggact cgattaacgt
     2161 ttccataagt atcctcccca aaatatgcgt attcgcattc tattcgtatt ttactttagg
     2221 aagtcgcaaa cttcaagaaa agacttgcaa ctaaataata tactttagtt atttaagaaa
     2281 actccactag aaagagagcc tcagtgtgtt tgtctgtggc cctcctactg aaaaatttgg
     2341 tttttaaaat catttttggc gataggttgc taggaattct ctcattttct tagctgtttg
     2401 tttcaaatca tccattttag gaagataaac gattcgaaaa tgatctggct ggttccaatt
     2461 aaatccacca ccatgtacaa gtagaatatg atgttcatgt aaaaagtcca aaacgaattt
     2521 ttcatcatcc aaaatattga atcgctttgt atcaattttt gggaatatat aaaaagcagc
     2581 ttttggtttt acggctgaaa gaccaggaat atcattgatt gcattataga tatattctct
     2641 ttgttcatag atccttccgc ctggcaggag cagctcatcg acactttgat aaccgcctag
     2701 cgcggtttgg ataatttgct gagacaatac attggaacac aaacgcatgg aggacaacat
     2761 attcagccct tctatatagc ctttgacgtg tgacttatct ccacttagga ccatccagcc
     2821 tactcgaaat cctgctacac gatgagattt ggatagaccg ttcagcgtaa caacgaacaa
     2881 atcaggcgct aatgtagcaa tcggaatatg ttctagacca tccatcacta agcgatcata
     2941 gatttcgtcg gaataaataa tcaggttatt ttgtcgagct acttcaacga tttcttctaa
     3001 taattctttt ggataaagtg ccccagtagg attattagga ttaatgataa caatagcttt
     3061 tgtccgactc gttatttttg atttgatatc atcaatatca ggataccatt ctgcctcttc
     3121 atcgcaaata taatgaacag gtgtgcctcc agctaatgca atagaagccg tccacaacgg
     3181 atagtccggc attggaacca gtacttcatc tccattgtcc agcaacccct gcatacacat
     3241 cgtgatcaat tcgctcactc cgttgccggt gtagatatca ttgatcgtca cattcggaaa
     3301 atgtttcagt tggcaatatt gctcaattgc ttttctagca gaaaagatcc ccttggaatc
     3361 tgagtagcct tctgagtcac gggcattcat gatcaaatca cgaatgactt cgtttggtgc
     3421 ttcaaatcca aaaggtgcgg gatttcccgt gttcaatttt aaaatactaa tgccctcttc
     3481 ttgcatccgc tccgcttctt ctagaacggg accgcgaaca tcgtaactga caccttctaa
     3541 tttgttggat ttttcaaatt ctctcatcac ttagccaatc cctcatttca aaaagttaga
     3601 actttccaaa ttttttgtta tttactattt caatatcata ctccatccta gaaaattttg
     3661 ccacttattt aggaaaaacg taagtattaa aaaaacacaa acaagcgttg agaacttaat
     3721 tgtcatgata gtcattccat agattcgctg cccaatccat tgcaattcca caaatgattc
     3781 ctagcataaa accaagcaaa aaacgtccga atgcaagtcc aatcaataca cctaagatca
     3841 ttcccagtcc tgaaaattct ccgtcatatt tctccatctt aataagtcct cccatttttg
     3901 agcttgacaa ctatgtaaaa cctcgctatc attagtgtgt tattattacg cagatgtgtt
     3961 ggaattggca gacaagcatg attgagggtc atgtgagcgt tagctcgtgt gggttcgagt
     4021 cccatcatct gcactacaac tcgtgaagtt aattttgctt cacgagtttt tttgtttgaa
     4081 cgtttcttta tgccattata tacatatcac tgtatccttt acaaaaagaa cgtacaatca
     4141 tgtaaacagc ctgaggtgag tatatgaagg tcggaaacaa gctactcgta gaaacttgca
     4201 agtgttaaaa caattaatcg aaaaacgagt aaaatccctc acctaatact aaagcgaggg
     4261 attttttgta tattatctgt ttatcaccgt tattataaag gtacaaatac caagcacggt
     4321 taatccaaat tgcataaatt catttttttg tacactcatg cttttcatta gctctttaac
     4381 tgccattagt actaagatgg cgataacaac ataaagtata tagtacgtcc gcattccgga
     4441 agcccatact gtgggagaaa atcccataat taaccttgaa caaaatccca ttatcatcaa
     4501 aataactaaa aaaatagaag ttttcttatt gtcaaaactt aaataaattc caacaattaa
     4561 acatagtaat aatgccaaga ctactaaagt agctatccaa gtacctggat aaaaaagtga
     4621 cagtttcgtt cctaactctg taaagagatt attcaggtta ctactactcc aaatcattgc
     4681 ccttttattt ccattgacgt aagtaaagct ttgacccatt gtattaccaa aataaataat
     4741 caggtttaag aaaaacggta atgcagtcaa tatacgcaca taatagtttt gacatttcct
     4801 atatgttaga aggaaaatta agaaaaatag caataaaaat aagatattca tgtctaaaaa
     4861 aaacggcttt ccaaatgatg aaatacctaa atctaactta ttaagaaagt tgaaattttt
     4921 atattcagga aaccatttat taatttcatg tgcagcacgt aatgcattcc ctggagttgt
     4981 caaagagaaa attaattctg ctaagcttat tattgaaaat actgataact tataattata
     5041 tcgtccattg acaatcaaat ataaactaac tatacttgtt agaacaaaaa aacaggcgtt
     5101 gacttgttct tgattagtta aaaatatcaa taaaggaata cttacccaat atatttttct
     5161 atttatttct tctcctctta agagttgaaa aaacggataa aaagttagta aactaaatgc
     5221 tactggccac tgatagttca aggtggttgc tctccaaccg gtttccccca ttactgtcaa
     5281 tg
//
LOCUS       DACGDM010000135         5108 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.143, whole genome shotgun sequence.
ACCESSION   DACGDM010000135 DACGDM010000000
VERSION     DACGDM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.143"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            369..1559
                     /locus_tag="IXR05_002671"
     CDS             369..1559
                     /locus_tag="IXR05_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HAQ4261115.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            1693..3882
                     /locus_tag="IXR05_002672"
     CDS             1693..3882
                     /locus_tag="IXR05_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4261116.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            3879..>5108
                     /locus_tag="IXR05_002673"
     CDS             3879..>5108
                     /locus_tag="IXR05_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4261117.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILI"
BASE COUNT         1849 a          775 c          913 g         1571 t
ORIGIN      
        1 gttttcaacg taaagtgtat aaaacagaat gcgatactat caagggagtt aaaacaatat
       61 acagaacagt aaaacactat aaataaaaat aaaagtgcaa taaaagtgca atttttgcac
      121 ctaatcatac tctgtttata tatgaaaact agattctgaa tccaatattt ggttaacgag
      181 aggcgttcga atttgaacgt cttttatata ttactttcaa ataaatatga ggtagaatac
      241 tatctatttt ctttttaacc caattgttat aatggagagt gtaaaatatt ttgtgtaaat
      301 agaaaaaagg aagtcccttc tgtagaatag agttaccaca acacattcac agaagagagg
      361 acttccctat gaacgatttt actacagaaa ttctaaagac tctagcgaac aaaggcgatt
      421 tgaatgaatt attccgtgtc catttggaga aagcagtcaa tacgcttctc aaaacggagt
      481 taacggcttt cctagattac gaaaagtatg atcgcattgg ttttaacacg ggtaattctc
      541 gtaacggctc ctatgaccgt acggtcaaga ccgagtatgg ggaacttcat ctccagattc
      601 cgcgcgaccg caatggtgag ttcaagcaac agactgttcc tgcttataga cggacgaatg
      661 acacgttaga ggagaccgtc attcacctct tccgaaaagg tattaccatg tcggaaatcg
      721 cagacttgat tgagaaaatg tatgggcatt actacacgcc ccaaaccatg tccaatataa
      781 caaaatcatt tacagaagag gtaacggcgt ttaatgggcg ggagcttcat gaccgttatg
      841 ctgctattta tatggacgca acgtatattc cgttaaagcg gaaaaccgtc gccaaggaag
      901 ctattcatat cgcagttggc attcgcccgg acggatcaaa ggaagtattg agctatgcga
      961 ttgcaccgac tgaatccatc acgatttggg aggaaatttt attggacctt caagagcgcg
     1021 gtttgaaaaa tgtcctcctg ttcatcacgg atggcttaaa ggggatggta ggagcgatta
     1081 gtcggttcta tcccaaagct cgttttcaac attgttgtgt acacgtttcc cgtaatatca
     1141 gtcataaagt gcgtgtcgat gatcgtaagg aagtctgtga tgattttaaa atggtgtatc
     1201 aagcctcatc taaagaggtg gcgttggaag cacgtggtac ttttgcggaa aaatggaaaa
     1261 ccagctatcc aaaagtggtt gaatcgattc tttcgaacga tcacttgctc actttctatg
     1321 atttcccctt ggccatacgc aagagtattt attctacgaa cttgattgaa tcctttaata
     1381 aacaaatcaa gaaatacagc caccgcaagg aacagttcca aaatgaagag tcgatggaac
     1441 gtttcttagt ctcgtctttt gatacttaca accaaaaatt cctaggtcgc agtcataaag
     1501 gtttccaaca ggccgaaggc gagctcgaac aaatgctaag ccaactgatt gagaattaga
     1561 aacaatctgc agtagggaag aatcatttac acaaaattat tgacgctccc ttataatgag
     1621 aacttttact aacataattt atgataaact tactatataa tcatattaat taaatagtta
     1681 ggagatctgc ttatgtttat atctactctt caaattcgaa attttagaaa ttatgaatcc
     1741 gaaatctttc gattcgataa tgagacaaat actattatag gtgagaatga ttcagggaaa
     1801 accaatgctc ttactgcatt gagaatctta ttagatgata gttattacta tagtagtaaa
     1861 acactaaaag aatcagattt ttttcatgga attcaaaatg ggtggcaagg gcattggatt
     1921 attatctctg cgacatttga aggaatcagc gaagaagaat ttgacaatga gatttgtgct
     1981 tccatttctt taaattctga aagtcaaaca atcttagaag aattgatttc aaatgcagat
     2041 aaaggtgtag gtagtatttc tctatttatt agacctaaca aagctattag aaagcaatta
     2101 tttgatattt ccactgaatt agactctcat caatttaacg aatttagaaa ttctattcgt
     2161 ctatccgact atgaatttta ctacacatct aaatcaaatc taaatttctg tatcaatgaa
     2221 aattatgata aattggtagg aagactcaat gacaatatag ctagtaatcc tgaagaagac
     2281 gatgaagctc tgttgggctc aagaattgac atgtcagata ttttcaagca tatttcggtt
     2341 gtttatgttg acgctcttcg agatgttctt agagaaatga aaaacaatcg aaacccagtc
     2401 aaaagaatca tggaaacaat tgaatcaaaa atatcatcag ataatgttga gtcattaaaa
     2461 acaattatac agcaattaaa tgagactatt accagtgttc ctgaaattag gaaaattggc
     2521 gaaaatatta atcggcaact aaatagcata attggttcag tgtattctcc taatcttctt
     2581 ctttcctcaa ctatgtcaga tgatatgggt tctttagcaa aatttctttc aatgaagcca
     2641 gaacaaaata tcgacttaga cttactaggg ttaggacatc taaatatgat ttatttagct
     2701 ttgaaaatag tcgaatttga agcgtgtcgt tcaagagaac tacttaatat tatgttgatt
     2761 gaagaaccag aagctcatat tcatcatcat attcaaaaaa ctctgttcga aggattaaat
     2821 cttcaaaaaa actatactca gattctcatg accacacatt ctgtacattt agctgaagtg
     2881 tctgaaatat ctcggatgaa tgtattaaaa tcgtttaatg gcaaatctat cgttatgaat
     2941 ccagcaaata atctgaactc atttgctaaa gaaaagttaa aaaagaacaa tctaaatcta
     3001 ataaacgcag tagagagata tttagatgtt aaaagaaatg gattgctttt ttctaaaggt
     3061 gttatcttag ttgaaggaga tgctgaagaa atacttattc ctcaaatagt aaaaaaatta
     3121 tttggtataa acttagacga acttggaata ggtttgatta atgttggtag tacttcgttt
     3181 gaatatatcg ctagcttgtt tgacgatgat agaatacaga gaaagtgtgc tattgtaact
     3241 gatttagatg aacaggcaat cccatcagaa catcgattgt ataaaagcac tgcacaagag
     3301 aaaggtcaag caagaaaaga aaaattatcc tcccttttta atgaaaacaa ttgggttaat
     3361 tgtttttatg ctaatacaac atttgaaatt gagtttttag atgtgaataa agaaaatatt
     3421 ctaacttatg tcagtccaat tatagatgac gcattcaaag ataaaaaaac aataactgct
     3481 tataaagaag aaatacaaag tgaacaatat ttagaaagaa atttagcgat gttaaaacta
     3541 gccaatcatg ttggtaaggg gtggtttgca attgagttag gtgaaaaaat tgacttttta
     3601 atcaaaattc ctaagtatat tcttaatgct attgcttttg catgtcagga aatagtagat
     3661 ctctcaattt ataaaaaaat tctactccat acaatcgact tgtacgagga aactacagaa
     3721 ttgtcagctt tatcagctag tttaaaaaca agtgatacag ctgatttgaa tatagcaata
     3781 atttctttat tagagtactt tggtaaagat gaggatgttg tgtatctaat caatcagata
     3841 gaaaattaca caaaaatact ttatgctgag gtttcaaaat gacaaatatc ttcgaaaaaa
     3901 tcgtaaatga tttaaattta gaacaaaaag atgttgtgga aagtgaagat aacctttatg
     3961 taaatgcatg tcctgggagt gggaaaacaa gggtacttac aaggaaaatt gcttaccaag
     4021 caattaaaca cgatggatca ctaaaaagaa taattgctat cacatacact aatagagctg
     4081 ctgaagaaat taaggaacgc ctaagtttac ttagtataga tgatgatatt aatatttggg
     4141 tggggacaat acatcagttt tgtcttgaat ttattattta tccttttaaa atgaatctct
     4201 caagagtatc aaaaggattt acaattattg atgattatac tcaaagagct tacgtcagcc
     4261 aaattaataa tatgctgaat ttaaatctca aaacgtatga actgaacaaa attgatttgt
     4321 cactttctca tgattttaaa attaatgaag ttcagtatac tcaagtttct gaaatgtatc
     4381 acactatgtt ggaaaaaaat aaagaaattg attttgatat gattttacta gtagcgtata
     4441 aaattttaac tgtaaacagt aacgttgcac gtaatattgc tagtaatata agggcgattt
     4501 atgtggatga atttcaagat actagagaat tacaatacaa tgtaatagct aaattacttc
     4561 aaaacaaccc tcaaattcag tcaatgtttg ttggagatat tgaccaagca atttatggat
     4621 cattagatgg tatagctaaa tcagttgaag aactagaaat gctaactagt cacacttttc
     4681 aatcaaagac gctacatggc tgttacaggt ctaatcagag attagtagac ttctactcta
     4741 attttcagag ttgtccttac gagattgaaa gcagagggaa taataaaaac gaccgtggtt
     4801 ttataagtta tgattgcaaa gttactaagg aggatttacc caacataata aaaaatataa
     4861 taaaggaaaa gattgaaagc ggcattcatg aaaaagatat ttgtgtactt gctcctcaac
     4921 actatcctct gttttcactg ggtgagtatt taaagaaaga attaccgtat tgcaattttg
     4981 atgctataaa tatatcacca attaaggtaa ataatcatag tttatttttc aagttagcaa
     5041 ttttgtactt tactgaatca ggtgaaaagg ttcgaagaag aaagctaatt gcaaacgata
     5101 ttttaatt
//
LOCUS       DACGDM010000136         5031 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.144, whole genome shotgun sequence.
ACCESSION   DACGDM010000136 DACGDM010000000
VERSION     DACGDM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.144"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            136..795
                     /locus_tag="IXR05_002674"
     CDS             136..795
                     /locus_tag="IXR05_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAQ4261118.1"
                     /translation="MKIVAIVPMKLNNKRLPQKNTKAFTNGKPLCYYILSTLLKVKQI
                     DKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQVLAGFTKEVEADVYVMTHTT
                     APFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGEPFNYELDNIPRTQDLPPLY
                     EETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDIDEAEDFMIADAIYNHLILQG
                     S"
     gene            814..2397
                     /locus_tag="IXR05_002675"
     CDS             814..2397
                     /locus_tag="IXR05_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-3-methylglutaryl-CoA lyase"
                     /protein_id="HAQ4261119.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            2532..3110
                     /locus_tag="IXR05_002676"
     CDS             2532..3110
                     /locus_tag="IXR05_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261120.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            3056..3574
                     /locus_tag="IXR05_002677"
     CDS             3056..3574
                     /locus_tag="IXR05_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261121.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            3582..4622
                     /locus_tag="IXR05_002678"
     CDS             3582..4622
                     /locus_tag="IXR05_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAQ4261122.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            4871..>5031
                     /locus_tag="IXR05_002679"
     CDS             4871..>5031
                     /locus_tag="IXR05_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4261123.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         1861 a          575 c          982 g         1613 t
ORIGIN      
        1 aaacattatt tcaatgatta agagtcgaga gcacaaacgg tagacgatgt tatttttata
       61 aaaagatata atttattaat ggtcgataat tatgaaagga aaaatattct taaaaaaaag
      121 agtataggat gtcgtatgaa aatagtcgct atagtaccaa tgaagttaaa taacaaaaga
      181 ttgccacaaa aaaacacgaa agcttttacc aatggaaaac cattgtgtta ttatatactt
      241 tcaacacttt taaaagtaaa acagattgat aaagtgtatg tctattgtag taacccagat
      301 attaaagaat ttataccaga aggtgtaaca tttttaaaga gatctagttc cttagatcag
      361 gatacaacga gtattacaca ggtattagcc ggtttcacaa aagaagtaga ggctgatgta
      421 tatgtaatga cacacacaac agcaccattt attagcgaaa aatctattga aaaaggacta
      481 gatgccgtgc tgacaggaga atatgattct gcatttgctg caaaaaaatt gcaagatttc
      541 ttatggaaag acggtgaacc atttaattat gaattggaca atattcctag aacacaggat
      601 ttgccgcctt tatacgaaga aactagtgga ttttatattt ataatcgcaa tgtgatgacc
      661 gagttgcata gaagaattgg gaaaaaacct tgcatagttg aagtaggtga gattgagtca
      721 gttgatattg atgaagccga ggattttatg attgctgatg cgatttataa tcatcttatt
      781 ttacaaggta gttaagacag ggggaaggtt aggatgaaca atgtacagat tttagattgc
      841 acacttagag atgggggcta ttgtaacaat tgggaatttg gatttgataa tacaaaaaaa
      901 attatttctg gacttataga atcaggaatt gagattatag aatgtgggtt tctcacaaat
      961 aaaacagtat acaataaaaa tgttacaaaa tatacgacct tagaagaatt agcacagata
     1021 attcctgaaa aaagagaagg aaaattattt gtagcaatga tgaactatgg cgaatataat
     1081 atagaggatc ttccagatta tgatggttca tctattgatg gaattaggat tgcgtttcat
     1141 aaaaaaaatt gcaatgaagc gttgaaatta tgtcgtgaga taaagaaaaa aggctactta
     1201 gtttttgttc aagctatggt atctctcaat tatacagatg aagagttttt agcagtaata
     1261 aaaaatgtga atcagtttaa accatacgct ttttatattg ttgatagttt tggaatgatg
     1321 aaaggaaaag atttaactcg tcttttttac atgattgagc ataatctaga aaaagatata
     1381 cagataggtt ttcactcaca taataacatg cagcttgcat attctaatgc acaaaaactt
     1441 ataaccgtac aaacaaatcg aagcctgatt attgattctt cggtgtacgg aatgggaaga
     1501 ggagcaggta atcttaacac agaactattt gtagaatatt tgaatgataa tgcaggaaaa
     1561 aaatatcaat taaaaccatt attatatata attgatgaaa tactaaatag tttctatcag
     1621 aagagttatt ggggatattc attaccaaac tatatttcag cagttcataa tgctcatcct
     1681 aattatgcaa gctatctgtc atataagaat actttaacaa ttgaagcaat gaatgaaata
     1741 ttcgaaatga tggatgaaga aaaaaaggta tcttatgata aacaatatat agaagattta
     1801 tactacaaat atatggaaac tgggaaaata caggaggaat atatggaaga actgagaaaa
     1861 tttctctcag acaaaaaaat tctactgatt gcaccaggaa aaagttctgt agatgaggta
     1921 gaaagaataa aagagtttgt taccaaagaa gaagtcgtaa taattagtgt aaattttgaa
     1981 tattctcata tagatataga ttacgtattt ttaagtaatt taagacgttt tcatgaatta
     2041 ccgaaagaaa gcagaactaa atgtattgtt acatcaaata tacaagcatc ggatgtatat
     2101 ttacggacga gttataaaaa gttgttatct gaaagggaag ttgtaagaga caatgcagga
     2161 ttaatggcaa ttagattttt agccgatatg aatgtggatg aaatattctt agctggattt
     2221 gatggatatt cacataatga agatgagaat tatggtgagc aatccatgga aattataaca
     2281 aaatttgcat tattagatgc aatgaacgtg caaatgagag atgaattgtc agaattagct
     2341 aaaaaagtaa aggtgacatt tttaacggat ccacgttggg ttcgaattga taagtagtag
     2401 taataatgtt tttaaaattt tgataaagag atagtgagag aataaaaatg ggtaaagtct
     2461 taaataaaaa agaagaaaaa tatttaaggg acgatggggc gagatgaaac tctaattttg
     2521 aacttttaag aatcatttct atattgtgta ttgttgctta ccatgctaat ttgcgtttaa
     2581 attataatgc agacggaatt atagtacatg gttcattaac tgctaaccag attttcttga
     2641 attatattgg tatttggggt cagctaggag ttaattgttt tatatttatt tcggcatatt
     2701 ttttaagtga gaaaagaaac attcactttg aaaatgtttt gggaattgta ttagaatgta
     2761 ttttttatag tgtattagtt tatggaattc tttgtgcatg tggaatagaa acattttcat
     2821 tgaacagctt tgtaaaagaa atattatcat ttgctctagg tagatattgg tttattacat
     2881 cctatttagc attgtatatt ctaagtccgt atttaaatat catgcttaac aatctggaaa
     2941 aacttcagtt gcaaaaaata agtatgttat tgtttatagg tgtatgctgt tatcgtatgt
     3001 tatttaaaac atctttgttt ggggattgtg ctgttttaat tgcactatat gtcatatgtt
     3061 atacactgaa aaaaacgata ataatatttt tgagagacac agaatcatag gaacaattgt
     3121 atgtataaca gttataccac ttctcatatc cataggaata cttttcaaat ttataccaaa
     3181 tgcaatggtt aaccagatgg ttcatattgg ttctccattg atggttatag caagtatatt
     3241 tttattttat gtatttaaaa atttttcatt ttacagtaag tatataaata aacttgcgag
     3301 aaccagttta ggggtatata ttttacatga aaatcattat ttcattgatg gtatgaagtc
     3361 tagaggctta atatgggatg ggatatttgg attaggcaaa aggtttttag atagggattt
     3421 ttggatttgg tttataattg cagttgtagt tgtgtgcata atttgcatgg ctatcgatgt
     3481 tgtaagagaa aaatttgaaa gacagatttt taaaattaag agtgtaaaga acctgtgtaa
     3541 acttatgaat catgttataa atatataccc ataattaata aatgaggaga aaagaagtga
     3601 aagttatatc attcggagaa ttattattga gacttgcagc acccggttat tcaaagttat
     3661 ttcaaagaga tagtttggag actacattct gcggagggga agctaatgta gcggtatcct
     3721 tagcaatatt tggatatcaa tcagaattta taacaaagct tccggattca gatgttggat
     3781 atgcggcagc taatgctttg cgttattttg gagtaaatgt tgataatatt atatttggag
     3841 agggacgcat gggactgtat tatttagaaa aaggagcagc tcagagacca tctaaagtaa
     3901 tttatgacag aaaattttct gcaatttcgt tagctgatag tgatgaattt aagtggaagg
     3961 agatcctaaa cgatgcaaat tggtttcatt ggacagggat aaatccagca ttgtctgaga
     4021 atctctttga gacgtcctta gatgcatgtc aggctgccaa aaaaagaggt ataacaattt
     4081 cttgtgattt aaattatcga tccaagcttt ggacatcaga ggaagcaaaa gaaaagatgg
     4141 aacagatact accattggtt gatatttgta tttgtaatga agaagatgca gaaaaagtgc
     4201 taggaattaa agctgagcat acaaatatta atagtggaga attaaataaa gatggctatg
     4261 tgcaggtggc tagggagatt cacaagaagt ttggatgtag gtatgtagct acaactctgc
     4321 gtagaagtta ttcggcaagt agaaatggtt ggagtgcaat gttatacgaa gcagaaaaag
     4381 ataaagcgta tttttccaca gaatacaaca tacaaattgt tgatcgcgtt ggtggtggag
     4441 acagcttttc tgctggtata atatatgcgt tatgtgaaaa tatgtccgga caaaaggcta
     4501 ttgaatttgc gactgcatct agttgtttaa aacatactat agaaggtgat tttaatcgaa
     4561 ctacaattga ggatgtatat aatttaatga atagcggtgg aaatggtcgc gtgttgcgtt
     4621 agtcaacata taaagataaa tcacagtaat ttttatggtg attatctgtc ttagtagtga
     4681 ttagaataac gtgaaaataa attgttgagc gtttatactg ttttgaaaaa taaatttaac
     4741 atattgaaaa atacaaatat atacgtatat tataaagcgc cgattgtaaa attaagctag
     4801 acaactaaaa cagtcatttg tgctacactc aaaatagttc cgaccaaaga attataagga
     4861 gtgagtgcaa ataacctata cctatcttac aacggatgaa cttgtaataa tagagtctta
     4921 tttgaaaatt aaccaatctg ttgctaaaac tgcgcattgc ttgaatcgtt caagtcaaac
     4981 gatccataaa gtatatctgt tcttcaagca aagaaaatca gccttagaat a
//
LOCUS       DACGDM010000137         4846 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.145, whole genome shotgun sequence.
ACCESSION   DACGDM010000137 DACGDM010000000
VERSION     DACGDM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.145"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..290)
                     /locus_tag="IXR05_002680"
     CDS             complement(<1..290)
                     /locus_tag="IXR05_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4261124.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTET"
     gene            complement(283..624)
                     /locus_tag="IXR05_002681"
     CDS             complement(283..624)
                     /locus_tag="IXR05_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261125.1"
                     /translation="MNKELSTLDQYLTDSEWGKSNIKETNNRKIRRNLLTNEELSCDQ
                     DDLGNFVSIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYNRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            complement(798..1523)
                     /locus_tag="IXR05_002682"
     CDS             complement(798..1523)
                     /locus_tag="IXR05_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAQ4261126.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFKKKHKHVLEAIESIKRSVENS
                     ANVEDGSNFGQMFVEGNEPDSYGRSRRVYFMNRDGFSLLAMGFTGSKAINFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRMEIDQLNRQQRLFGDENE"
     gene            1576..2052
                     /locus_tag="IXR05_002683"
     CDS             1576..2052
                     /locus_tag="IXR05_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261127.1"
                     /translation="MRKKLNYILTATLTIYIILFITLSFLSSIKKIPFITLNKNSILK
                     EFNNTDYIAFLKLFSVCVLISCVIIFIVAKTCWTMLNKNQRDVENIAIFLIKITSSIS
                     IIIPMTVTFSKEQFNVAATYLSFIALFSFVLPKRNKSNFDNKELDEVRNSSPKEQK"
     gene            complement(2058..2240)
                     /locus_tag="IXR05_002684"
     CDS             complement(2058..2240)
                     /locus_tag="IXR05_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261128.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEHRAKKASREGLTKI"
     gene            complement(2240..2539)
                     /locus_tag="IXR05_002685"
     CDS             complement(2240..2539)
                     /locus_tag="IXR05_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261129.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKSLSPSDVLKEAS"
     gene            complement(2644..2847)
                     /locus_tag="IXR05_002686"
     CDS             complement(2644..2847)
                     /locus_tag="IXR05_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261130.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(2862..3608)
                     /locus_tag="IXR05_002687"
     CDS             complement(2862..3608)
                     /locus_tag="IXR05_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAQ4261131.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            3686..3994
                     /locus_tag="IXR05_002688"
     CDS             3686..3994
                     /locus_tag="IXR05_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261132.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            complement(3965..4222)
                     /locus_tag="IXR05_002689"
     CDS             complement(3965..4222)
                     /locus_tag="IXR05_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HAQ4261133.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
BASE COUNT         1330 a          938 c          759 g         1819 t
ORIGIN      
        1 tctgtttccg tatgtccttt aaccgttact gagacagata cataagtccc tgtttcatcc
       61 ataagaaaag gtttatattc ctcaacaaga aagtcttgat gagttccaga aacaaccctg
      121 tagtgtttat actcattaat agttaccgtt gcctgtggat cattcttttt cataatctcc
      181 cacgcgtgag cccaagataa ataatcaaaa tttccttttt tcttgagaat tttatttaac
      241 ttacgactaa aaagtttttc aaagttcgtt gtccctttga tttcactcat caaattctgc
      301 ctccatttca gcaatgtatt tcttacctga tccgtaataa gagatatcaa tcaagttatc
      361 tctgttgtac tcttctagcg catcaatcaa gccatcttcg atgacataga tgtattcagg
      421 tttatttgaa tgttttgata gatggataag gtaaacatga tcccaaatac tcacaaaatt
      481 tcccaagtca tcttgatcac atgatagttc ttcgttcgtc aaaagatttc gtctgatttt
      541 tcgattattt gtttccttga tattcgactt gccccattca gaatcagtca aatattgatc
      601 taaagtggaa agttctttat tcatatgcta aaattctcct tagatatgtt ttgtgactct
      661 atgcttgccg gctgagtcac ttttttattt gttgccatgc tttttgcttt tcgatatgtt
      721 gttggcttag gatgtttggt ttattgtgtc tccaccagcg attagcaatt accgtcccta
      781 ttcttagcgc ttcagctcta ttcattttca tcaccgaaaa gtctttgttg tctgttcagt
      841 tgatcgattt ccatgcggat cgcagtttct ggtaaccaca tttcaataaa tgaaacagca
      901 tcatcgaatc tcttacgagg taactcgcca tatcttggga ttgaaaaggt acgtttaaat
      961 tcagaccaaa attttgagaa tacttttttg ctgatttctt cataagctcg gctttctttt
     1021 ccccctagaa cttccataac tttcatattt cctttttgct taatttcaaa ctcttgttgt
     1081 ccgctaattc gcatagtatc tttaagcatg gaaacatctt ttttaacatc tttcatttct
     1141 tctaattgat agatcatcat gtcttcaatt gtttgaggaa cagtattctt ccgaataaca
     1201 tcttccattt cgttgaaagc ttcaataaat tttagtttga aatttattgc tttacttcca
     1261 gtgaatccca tagctagcaa ggaaaatccg tctctattca tgaaataaac tctccgactt
     1321 cttccgtatg agtctggctc gttcccttcc acaaacatct gtccaaaatt ggacccatct
     1381 tcaacattgg ccgaattttc gaccgatctt tttattgatt caattgcttc tagtacatgc
     1441 ttatgtttct ttttgaaact ttctgccact tgtaagctcg tagttacagc ttctttattt
     1501 ttcaaaatta ctaattcttg cattatttct tctctccttt ttggtataat tttcgttaga
     1561 aagtgaggtg attctatgag gaaaaagctc aattacattc ttactgcgac tttaaccata
     1621 tatataattc tgtttattac cttatctttc ctgtcttcaa ttaaaaaaat tccttttatt
     1681 acattgaata aaaatagtat tttgaaggag ttcaataaca ctgactacat cgcatttcta
     1741 aaactttttt cagtctgtgt gctaatatca tgtgtaatta tttttattgt tgctaaaaca
     1801 tgttggacaa tgttaaataa aaaccaacgc gatgttgaaa atattgctat atttttaatt
     1861 aagattactt cctcaatatc aattatcatt ccgatgactg taactttttc aaaagaacag
     1921 tttaatgtag cggctactta tctttcattt atagcgctat tttcttttgt tcttcctaaa
     1981 agaaataaga gcaactttga caacaaggag ctggatgaag tacgcaatag cagcccaaag
     2041 gaacaaaaat aaaaaaatca tattttagtc agtccctccc gactggcttt tttcgctctg
     2101 tgctcagctt catcaagccc cataaaaatc caaaccatgt aaacgattgt ccctatcaac
     2161 gcttgtctgc ttccccagag gcctaaagcg tagatgatta gcggtgcgct gaatactagt
     2221 gctctgttga atttgcccat taacttgcct ccttcaaaac atctgaaggc gataaacttt
     2281 ttacacgata tttgtttgcg tctttccact ttaaaaacca aataaaagta tggtaatgaa
     2341 taaatgtggt tgagtgacct ggacgaagta ttccttctgc aaattcagga attgtttcca
     2401 tttccttgca gtattcaact aaagtagttt ttgacatgcc gtggaacttc tccaagatta
     2461 aactttgtcg gtaccagtcg tctggtttta ctgccttctc agcagcttct atcagctctg
     2521 aaagtgttgg ttttttcact tattatccct cctaaaaatt atcgttccat actcgatgtt
     2581 taacatttct tgaagctctg attttgtaag aatgatttta tcttccaacg actttacctc
     2641 cctctacaat tcgtacatag tgataatcga atctataatt ctgtttgctt ctgcagaagt
     2701 ctttttaccg tttaaaatta aagataagta gcttttgcta attccaaatc tttcagcaag
     2761 catggtgtaa gttaagaact ttgaactttc gacatattct ttgatttttt ctctatctcg
     2821 ttgagtgatt tctgcaatgt cagtcatact aaaactcctt tctaaccaat ttcctctaaa
     2881 tccatttgag ggtaatagcc ctctgcgatt aataagttgt aaataaacac tcgccctttc
     2941 tgtgtccatt tggtattcat tacaacttta gtgccgccat cggctttcgg tatctcactt
     3001 gtgtgcgatt ttgtgtatcc ttggttcata tgttttcggt aaagtatcca ttgtccgcta
     3061 actttatgct gaacacctaa ctcgtttagc aatttgttta gagcaattgc cgacattccg
     3121 taatcagctg caatttgaga agtagctacc gtatctgtcg atgaaagaat cgtatctaag
     3181 tagctaatct ttggttcgta ctcggcaatt tgttgttcga gtaattggtt cttttcttct
     3241 aaatccgctg ctaaacgcaa tgcttgtgca aaactttgag gtacgtttga atagctacct
     3301 gtttttctaa ttgttggaag gacttcactc gttacccaac gtttaaattt tttggcagag
     3361 ggaagttttg attttaagat taaactgtaa aggcctgact cgttaatcaa aacaactgct
     3421 gttccattga cggtgaacga atcgttctgc gtcttatcct ccaagtccac atgatctcga
     3481 atagcttttt gcggattcga atatcctaga acgtctgcta catcttttcc tacaaaatat
     3541 ggttcatcat ttactaaaat agttcgaact tcgttttgct cgaaattaaa aatttgtggt
     3601 gtattcatat ttctcattcc tttctttggt ataatttcct tatcagtgtg acaggctgaa
     3661 ataattgtta aggaggtgaa aatttatgaa accagaattt gtaattacta tgcttgatgg
     3721 agaaaaaatc aaaatatttg ccgatacttt ggtcgttgga tacgatgatg cgtcaaatat
     3781 cgaagaaaaa gatggaatgt tctattcttc tcaaatttac gtgaatacct tgcaaggtga
     3841 tattggggta tctactcttg caacatcaag accgcttgta ggtcttatcg gctttttgtc
     3901 aaaagcaaca ttcttttctc tcggcgatga tatagattcg gatgaaactg tcatctataa
     3961 aacatcagct gttaaaagta tcggtttcaa atagtaattc ttgctcgttg atagcggaag
     4021 ccaacttttc ttccaacaca tcggcgagct ttctttttgt tggattcatt tcaaagttga
     4081 tagtcttgag aagcattttt gcatccttaa ctttttgtcc ttgcaattcc ttgatgattt
     4141 tatcggcttg gctatcaatt ccatgtgtta gatcatctat cattttttgt accttgattg
     4201 tttggctcat ttccttgttc attgtttagc ctcctttaat aaatgatttt ttgtattttt
     4261 taatttccat aaattcctca aattgctctt tggtattatt accacgacca tacatattgt
     4321 gaaattcttt atggcaactg acacaaagtg taacgccgtt tgaaatcgct gcggatttag
     4381 ttgttgcatg gctaaatcac gaatcacaag tatctactaa aggcgaatca atttcgccaa
     4441 aagaaattgt tcaagcttat ttagatattc attatgctgt tatctatggt cagcttccag
     4501 aagaccgtaa aaacgatgac taaacgtgag ctaaaatctc tgctatggct gcaaccatgg
     4561 cagagtcttc tttatctacc gcgtgttcca tcgccacttt tgcttgtttc agtatgtcta
     4621 atttcaaatc ttcgattttt gccgagactg ttttttccat attcttctct cctttctttt
     4681 atattcgtaa acaaatttaa caacttttta aaaaactgcg ttgactttat tagattaata
     4741 atctatacta aatgcatagt taaataagac atataaactt tgatttaaaa agctttcttg
     4801 gcggttggca tttattaatc aatagtattt tttgttgtct ttttag
//
LOCUS       DACGDM010000138         4839 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.146, whole genome shotgun sequence.
ACCESSION   DACGDM010000138 DACGDM010000000
VERSION     DACGDM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.146"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(220..972)
                     /gene="xth"
                     /locus_tag="IXR05_002690"
     CDS             complement(220..972)
                     /gene="xth"
                     /locus_tag="IXR05_002690"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAQ4261134.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1085..2005
                     /locus_tag="IXR05_002691"
     CDS             1085..2005
                     /locus_tag="IXR05_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4261135.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQEADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2078..3013
                     /gene="murB"
                     /locus_tag="IXR05_002692"
     CDS             2078..3013
                     /gene="murB"
                     /locus_tag="IXR05_002692"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAQ4261136.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3311..4789
                     /locus_tag="IXR05_002693"
     CDS             3311..4789
                     /locus_tag="IXR05_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4261137.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT         1697 a          778 c          935 g         1429 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
       61 cttattactt gatgcaggac agctttttca caatctctcg ataaacagtg ttcaaaagcc
      121 agtttctcgg tattatgcca aatttatgca aaatgtggaa agccattttc acaaaatttt
      181 tcttaatact cgaaactaaa cgactttttc acaacctctt tatttcaaat ctaattctac
      241 tggacaatga tcactgccca taatgtccgt atggatcttt gcatcagcta gtcctggctc
      301 taaatctttg ctcgtcaaaa agtaatcgat ccgccaacca gcattgtttt tccttgaatt
      361 gaatcggtag ttccaccaag agtagacacc ttcctgggtt ggataaaaat aacggaatgt
      421 atcgataaac ccgttatcca acagtcgaga aagagccgct ctttcttctg gagtgaatcc
      481 agcatttttt tgattcgttt tccagttttt caaatcaatc ttttgatgag cgacatttag
      541 atccccacac acgatgactg gtttttgttt ttttagattt tccaaataat tataaaaggc
      601 ttcttcccat tctaatcggt aatctaaacg ttttaattcg ctttgagaat ttggcgtgta
      661 acaggttaca agaaagaaat cggaatattc caaagtaatc agacggcctt ctgtatcatg
      721 gatatcgata cccattccgt aagtggcatt caatgctggt tttttagcaa aaatcgctgt
      781 gccggaatag ccttttcgtt ccgcgtaatt ccaatattga taataacctg gaagatctaa
      841 atcaatttgt cctgcttgga gtttcgtttc ctgcagacag aaaaaatcgg cgtctaactc
      901 atgaaaaact tctaaaaaat ttttatttac gatggcacga agcccgttta cgttccaaga
      961 gataaatttc aataaaagca cactccttcg aattaatttc cttacctttg cgatactatt
     1021 gtacctcatt ttagtaaaaa atggtgtaag atgaaagtaa ctaaatgatc caggaggaaa
     1081 gtagatgaag attggtgtaa tcggtgtagg gaatatcgca gaaaaagcat atttaccaac
     1141 ttatgcgaaa aaacaaggaa cacttgattt ttattttgca acaagaaata aagaaacaaa
     1201 agaaagaatt caaaaagagt acgggttcca acatctatat gaaacgatcg atgagctttt
     1261 agaagaaaaa atcgaagcat gtatgatcca cgcagcaaca aaagtacatt atgaattagc
     1321 caaaaaatgt ctagaaaatg gtatccatgt ttatattgac aaaccactga gtgtccatct
     1381 aaatgaagtt cgtgaattgc aagaattagc tgataagaac caaataattt tgatgatcgg
     1441 tttcaaccgg cgctttgctc ctatggtaga agaattgaaa cgtatcccag ataagcggtt
     1501 gatccacctg caaaaaaatc gaatagcggc aaaagaaacg acagagttcg tcctttatga
     1561 tttgttttta catcttattg atacagctgt gtatttatta gatgaaccca ttttgagaac
     1621 aaaataccag ataagagaaa caaaggaatt tttggaatat gccattttac aattagaaac
     1681 acaaaatcaa acggctattt taacgatgga tttagcaagt ggcgctaata tagaaaaata
     1741 tcaagtaaca agtaaaaatg gtacttatga agtaaacgat ctgacccagc ttgtcattca
     1801 agaggctgat ggaaaaaaag tgaaagaatt tggcgactgg acaaacacgc tagtcaaacg
     1861 cgggtttgag ccaatggtag aggccttctt ttctcagatc cgtttaggta aatcggaaac
     1921 agaattgctt aaacaaaaag aagttgtaag aagtcatgaa ttatgtgagg aagtgcttaa
     1981 agatcactac cgtcatcaac tttgaacaag actggcaaga ttgtattaag cgtgatagaa
     2041 taatgaggac gtttgagaaa agaaaggaaa atcctcagtg aataaagaag aaatagttga
     2101 aagcttagcc acgattacta tattgtttga tgaaccattg atgaactata cgtttacgaa
     2161 aacaggtgga ccagctgatg tccttgcatt cccgaaaaaa caagaagaag taaagcaaat
     2221 catcgattat tgccgaatcc atgatatacc ttggatggta ttaggaaatg caagcaatct
     2281 gatcgttcaa gatggcggga ttcgcggtgt agtcatcatg ctgactgaaa tgaaacagat
     2341 tcatgtcaaa ggaacgatgg tcattgcgga agcaggtgcc tcactgattg atacgactta
     2401 tgcagctttg gcagaatcat tgactggatt tgaatttgct tgcggcatcc cgggaagtgt
     2461 cggtggagcg gtttatatga atgcaggtgc gtatggcgga gagatcaaag atgtttttgc
     2521 tgaagtggat cttttgcttg aagatggaac attgaaaact ttgacaaaag acgaaatggt
     2581 attttcttat cgtcacagta aagtccaaga attacgtgct atcgtattgg aagctcgatt
     2641 cagtttgcaa acaggggatt atgaagcaat caaagcaaga atggatgagt tgaccgaatt
     2701 gcgtcaatca aaacagccat tagaataccc ttcatgcgga agtgtcttta agcgcccagt
     2761 aggacactat acaggtcagc tgatccaaca agcaggattg caaggcctga aatggggcgg
     2821 tgcacaagtc tctgaaaaac atgctggatt catcgtcaat atcgatcatg cgacagcgac
     2881 agattatatt gaattgattg cgcacatcca agaagtaatc aaagaaaaat ttgatgtgtc
     2941 tttagaaaca gaagtgcgga tcattggaga aaaacaagca atatcagaaa caagcagaag
     3001 tttagccaat taataagtaa tggaacttaa aataagtaaa agagcaggac ggtggccgtc
     3061 ctgctctttt ttgtggttgt ttacgcaaat ggcgcaaatc ttgtacattt taacacaata
     3121 aaacaaaaaa tatagaatat ttcctcataa atttttccat tttttgcaat attctcaaaa
     3181 aaaagataaa aaatgagaat aactgatgaa aaaacaagca taatccatca taaaatcagt
     3241 ataggtgaaa agatgaactt tcatctgcat atcaagtaat tggtatgagg cattttttga
     3301 ggtgtaggat atgaagttgg attaccttat agaagaggaa gatagagaaa aactgctgct
     3361 agctagatat ttagaatttg agaaaaagaa ttatgtagtg ctgcctaagt tatatgaaac
     3421 attaggtttg tctaaattta aaacaagaaa ttatatcata gaattaaata aagaatttac
     3481 tgaattcaaa acaaagccag agatccaaat ttcagaagaa gcagagatcc atgtcgaacg
     3541 tctgaatttg acggatatca aaaatttaag aagaatctac tttcaacgat caaaaattgc
     3601 tcgactgtta acggagatcg tggattcaaa agtaacgatc gaaaaatttg cagagaatca
     3661 ttttttaagc atatcaagag cctatgtaaa aagaagagaa ttagtctctt ttcttgaaca
     3721 gcatcaaata aagttaaaga aaaacatatt agttggggaa gaaataaaca tacggaacgt
     3781 attatttggg gtatatttcg gggtctttaa tggtttttct atgccattta gagaaagcgt
     3841 catgaatgaa gcaaagagta tcgtgcaata ttttgaatat ctgttcaatt taaaactgtc
     3901 tgcaacaaaa cgaatcaaat tcaatttgct aaccactatt agtttgttga gggcctatgg
     3961 gaatcaacca atcggaaaac gtttcttttc agatgaatac tttaagagct cagaaggaat
     4021 gaagatcatc aaggatttat cacatatttc ttttcttcat atccctaaag agcagatcat
     4081 tgatgagatt tcttatatca tgttgttttt gatcacggaa gaagaatttg aattagatgg
     4141 cgcatttgga cttgcggaag ctcattttca tgatatccac atgattagtc aaaaaatgtc
     4201 agtggaattg attgatcaat taccattttc gattgaaatc tctgaagaag aaagactata
     4261 tatacgaaaa gaacttcgta tgggtatgat gcatgtcaat cgaaaaaatt ggatattcga
     4321 ctttgagatg actagcttta cgtctaaaaa gcagctacag tttttcttcg agacgtatcc
     4381 aatattcagt acagcaatcc aaaaggtcat acaagagaat aaacgctatt tcttgggaaa
     4441 agatgaacgt ttcatgattc gcttatttta tgattatctc tttttattgg tcggtatttg
     4501 tccggtatca tattttgaag caccgattca tgtctgtatt gatttttcgc aaggatctgc
     4561 ttataccgat tacattattt ctcaagtgaa aggatttaaa aattacaata ttgtgattga
     4621 gagtcgaatc acttctcgta cgaatattta tttatctgat tgtttacttg aaaaatttaa
     4681 taaagaacag ataatttgga aaaatccacc gactccagat gactgggaat attttggaaa
     4741 taccatcatc agagaaaaaa atagacattt aactgaaaaa atcagctagt atttatggat
     4801 ggcagctttg tctcacatat ttattagctg atttatgtt
//
LOCUS       DACGDM010000139         4815 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.147, whole genome shotgun sequence.
ACCESSION   DACGDM010000139 DACGDM010000000
VERSION     DACGDM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.147"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(207..1169)
                     /locus_tag="IXR05_002694"
     CDS             complement(207..1169)
                     /locus_tag="IXR05_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4261138.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="IXR05_002695"
     CDS             complement(1171..2610)
                     /locus_tag="IXR05_002695"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAQ4261139.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="IXR05_002696"
     CDS             2795..4741
                     /locus_tag="IXR05_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAQ4261140.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1539 a          822 c          791 g         1663 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttaatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaat
//
LOCUS       DACGDM010000140         4791 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.148, whole genome shotgun sequence.
ACCESSION   DACGDM010000140 DACGDM010000000
VERSION     DACGDM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.148"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..253
                     /locus_tag="IXR05_002697"
     CDS             <1..253
                     /locus_tag="IXR05_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="initiator RepB protein"
                     /protein_id="HAQ4261141.1"
                     /translation="NKALELVNQQIYSEKDPTSLQEKIKEQKRKLELLQQLEELERKQ
                     NNLNKENKEINEQIPDNNSDIPPELKKGLLDNLQNLFKE"
     gene            263..760
                     /locus_tag="IXR05_002698"
     CDS             263..760
                     /locus_tag="IXR05_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261142.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNIIYLKKE
                     AVTTITKVLSGNEPGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQLALETQ
                     QKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQSKTEKKW
                     WQFWQ"
     gene            1136..1417
                     /locus_tag="IXR05_002699"
     CDS             1136..1417
                     /locus_tag="IXR05_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261143.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
     gene            1419..1835
                     /locus_tag="IXR05_002700"
     CDS             1419..1835
                     /locus_tag="IXR05_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261144.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPATNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            2487..2912
                     /locus_tag="IXR05_002701"
     CDS             2487..2912
                     /locus_tag="IXR05_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261145.1"
                     /translation="MICKNKKKIIAIIASFSLIFSTACTVLLTNNANVEAASSSYKHN
                     HAGYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPGIISLVFGSAVSA
                     NNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            4064..>4791
                     /locus_tag="IXR05_002702"
     CDS             4064..>4791
                     /locus_tag="IXR05_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4261146.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     YFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQ"
BASE COUNT         1760 a          816 c          786 g         1429 t
ORIGIN      
        1 aaataaagct ttagaactag ttaatcaaca aatttactct gaaaaagacc ccacttcatt
       61 acaagaaaaa atcaaagaac agaaacgaaa attagaactt ttacaacaat tagaagagct
      121 agaaagaaaa caaaataatc tgaataaaga aaataaggag attaacgaac aaataccaga
      181 taacaattcc gatattcccc cagaattaaa aaaaggctta ctagataatc ttcaaaactt
      241 atttaaagaa taaggggttt ttatgacaga taaaactatc aaagaattag cagatattct
      301 aggtgtttca aaagataaag tgaagtatca actgaggaaa ttacctagta attttaccta
      361 caaaaaagga aatattatct acctgaaaaa agaagcagta acaacaatta caaaggtttt
      421 atcaggtaat gagccgggta acttacctag tgaattacct gattcattac ctaccgatta
      481 cctactcaag gagattgaaa ctaagaataa tcatattgaa gaaaaagata ggcaaattga
      541 aaaacttcaa ctagctttag aaacacaaca aaaattactc gaccagcaac aacaactcac
      601 cctgcaagcc aaccaacaaa tcgagaaact gcaggaacaa ctacagttga cttatacgga
      661 agaatcttcg gaaaataaat caacgactct ttctgaagaa acagaatcga tagaaaaaca
      721 atcaaagacg gagaaaaaat ggtggcaatt ctggcaataa aaccagcaat ttaaattaat
      781 aaaaattgct ggttttattc ttctttttgc ttttgcgagc agagcaacat gggcccatgt
      841 tgcgatattt tggtggcgcc ccaatccccg ttttttcgtt gaatcttact cggactgcac
      901 tcgttttaca gctgattttt ctgaattttg aaagagcata aggaaacgtg gtatcacttt
      961 cttacgaaag gtgctagata agctgtgcct atcacgtttc tcagaaaaaa atttgctatc
     1021 acttttttgc cattgtggct aggctatgta tagtgttttg gcgaaaaata gctatacaaa
     1081 tactatattt gtatgatata cataaattat atactgatac gaaaggaaaa tttccatgga
     1141 cattttagtt cgaaatatca atcccaaaat tattacaaga atagataaac gttgtcagga
     1201 actaacaacc aaaacgggca aaaaatggag tcgaaatcaa tacctaaaaa ttttaatcga
     1261 aaacgatttt gaccacgaac ttatgaatta caaaaaagat caattcgatt tattattcga
     1321 aaaatttatt gccattcaag cagaaaatac gaacatacta aatgactatg ttcacacaaa
     1381 caaccaactc attgaaacac ttatcggagg aatataacat gagaaaaact tctgttcaaa
     1441 aacacgtaac cctttatccc agtcacgttg acgttttaga ttccatcatc gaaaaaaatc
     1501 cagacgtcaa caattattca gaagccattc gctttttatg tatgagttat gaacctgcta
     1561 ccaatacaac cacaaccagt aaccaagcaa aactcaatgc catgggaaaa gaaatttcta
     1621 tcatgacaga aatcatggca gaatttgctg atttatatct aaaagatact ggtgttctta
     1681 tcggtacaaa ttctaaagta tatcaagaag tgaaagaaaa aattgaaaat caactcaatc
     1741 cttcccgacg aaatcaaccc aaaaatcgtc aaaaagaaac caatcaaacc tttacttctg
     1801 gaaattttga cccaacaaac tttctaaaaa gataaaaaaa gaaaccgaaa aataaaaaaa
     1861 ttcctcgatt tctttttagg gatcggtctt ccagcaagat ttgcaagttg gtaccaactt
     1921 gcgaaaaaaa aaagaaaaat ccgcttctgc gaattcttct tttttcattt tggggcgctg
     1981 ccctaatccc taagtcccgg ttattcaata gcatggaaac tcaaagaata agacgttccc
     2041 tggaataaaa aaaaggctgc tcgttcgagc agtccataca taggaaaatg aaaaaacgac
     2101 gtcccttact gagaaacgct attaaacttt taacaaatcc tctaaaaaat aacaagtctt
     2161 taaaaagtga ccggtaaaaa tgcacaaaga actaaaaaag agaaattgca tcaaatcaag
     2221 cattagaagc tagtaactag ctagaccaat tgaaaatcac aaagtgagcg cctgtatcta
     2281 ttgctacagg cgctacttgg catagtgtac attatgtcaa caagaattta atataacata
     2341 tttttctagt ttgttataac aatgccactc taacaaaaat gtaagcatta tccttattaa
     2401 aagctccttg acaaggacta taccttttat tttatgattt ttacatagaa aacgttttct
     2461 ctattttttg tttagaggtg atttttatga tttgcaagaa caagaaaaaa attattgcta
     2521 ttattgctag tttctctttg atttttagta ctgcatgtac tgtcttatta acaaataatg
     2581 ctaatgttga agctgcaagc tcttcttaca aacataatca tgctggttat agatgttaca
     2641 aaatgagtta ttatgtaagt ccttctaaat gcaaacaatt ggctcgccaa actaataaac
     2701 ttaataccgt ctcagctatt gcaaacttta ttggactatc tggattaaca ccggggatta
     2761 tatcattagt tttcggatca gcagttagtg ctaataatgt atttgttaca gccgctagaa
     2821 gaggaaaagg cgttcaatta aattatattg cccattttag taataccact acctataatt
     2881 atagttctaa ccaaaattat gttataaaat aattaaaact ttaaactagg aggaatgctt
     2941 tatgaaatta acaaaaattg ctgtaatttt agctgttatt gctggcatta ttttatattt
     3001 tgtattgcct gctaatcaat tcttccttta ctttggaata cctgcgattt taatagtaaa
     3061 tggcgtaaga atctttgaac aacgaaaaaa atgtagctct acctaatcgt tacaaaacaa
     3121 caatttcacc ttcggtgaaa taagcgaaac tttacaaaaa gtggctagca aatgctagcc
     3181 ttttttgtat tgtagagcgt gaattttgag ggggattcaa gggggagctt gcgccccttt
     3241 gacaagcggt tatttgcacc aaatacctcc gtatttggct agcaatcctt ctaaaaaata
     3301 cacctatcga tcagagtcaa aacaaatcaa ttttcgagtg agcgaatccg aatttgcaaa
     3361 gctgaagctt tgcaaatgag tgtgccggct tccgtaaaaa tacatatggc tataatttgc
     3421 gttttaaggc gttttaaacg ttctggtata taattatacc aaaacaactt taaaacgcct
     3481 tagatctaat tttagaggtc ttatagaaca ttttagggtt gttagggctt gccctgaccg
     3541 cctgtaaggc gctttgagaa caagataagg gttttatact aagactgtct taaaacggct
     3601 taaacaaacg ctcagaactt ttcaaaggag ttctttatga actgttttta agcaaaggag
     3661 cctttaggcg actgcgcagt ataatgtgag agcgtagcga tcacacattt ttagtgaccg
     3721 tagggagcga gtttcccagt ttagaaaaat tcgcgaactt gtttgaggaa aaaagcagga
     3781 gttttttagg cgggaaattt tgcctcctct tttataatct ctttttaaac ctctttttaa
     3841 acctctttac cgtcggctgt atgcttactc tcccaaggtg tgcagaatct tttgggggtc
     3901 tttttgtctg tttttagggg tctttttgtc tgtttttagg ggtctttttg tctgtttttg
     3961 ggggtctttt tgtctgtttt taggggtctt taattagggg cttgacccct attagaaagc
     4021 tctttataat tttgttaagt agttaatctt gaaggaggat tttatggcaa atgaaattgt
     4081 gaaataccac catgaattaa atacgattcc tttacgcaaa tttacgtcag tagaaatgaa
     4141 tttattcttc tctatagtat ctagaatgcg tgacgtaggc gataaaaaag tacaatttac
     4201 attcgaacaa ttaaaagatt taagcaatta taaagcaact gcaaatgttc gattcataga
     4261 tgatttagaa acaacgtatg acaaattaat ggatttacgt tttggtagaa gaagtgctga
     4321 cggtttgcaa cgtgaacgat ttgttttatt taatcaattt aaaatcgatg gaaaagctga
     4381 tattcctttt gctgaaatac aagtccatga gaaagcctta cccttactta ataatcttga
     4441 agaatgggtt cgatattctc tccaacaatt caatgaatta gaaagcagtt attccaaaac
     4501 catgtttaga ttattaaaac aatacagaac caaaggaatt gcctattttt caaaagaaga
     4561 ctttcatgaa ttacttgata tccctaaaag ttatagagaa agtgatataa ataaaaaaat
     4621 tataaagcct attcgccaag aactaaccgc aatcttcaaa ggtctgacaa tcaaaaagaa
     4681 atacggaaaa ggaagaggaa aacctgtcat tggctatcaa ttcacgttta aacctgaaat
     4741 aaaaaaagca gacgacttta ataaacacgc accaacaaaa gaagaacaaa a
//
LOCUS       DACGDM010000141         4785 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.149, whole genome shotgun sequence.
ACCESSION   DACGDM010000141 DACGDM010000000
VERSION     DACGDM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.149"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..258)
                     /locus_tag="IXR05_002703"
     CDS             complement(<1..258)
                     /locus_tag="IXR05_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261147.1"
                     /translation="MERQESIREVQEVPTEQAKETQEGRSFSYGKNFSFLRPSIQISV
                     FVLWRIHNNRYSVGSQLFYQEICHALSKKYSQNAYKEALAFL"
     gene            complement(274..924)
                     /locus_tag="IXR05_002704"
     CDS             complement(274..924)
                     /locus_tag="IXR05_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261148.1"
                     /translation="MKKRFIYVCVGGLFLFGVGSTFFLIHEKLQLTAKEEKLTVEINK
                     FQEEKKGQEDLVTSLKEQLQQVESEVTTLKKANEELKNNDSTEKGNIQTFQKTVTEAF
                     EVLFNYEPDSFQERKNNCAPYLSDKLMKQYFKEGVSYGDSNGVSSELEKCSVYLKSTQ
                     KATIQGLVVVSYRNKIGDSSWNNAMNIFDVTFDPASKKITFMQNLGSSFNQQLLEE"
     gene            complement(935..2107)
                     /locus_tag="IXR05_002705"
     CDS             complement(935..2107)
                     /locus_tag="IXR05_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4261149.1"
                     /translation="MKKKLLLWCGFGCLPTLLLCMFGFLFMILLISSGSEEEEIDCSP
                     TEIVASTISLTNQGMETNGLQIAKEVQKHIPNTTLEGLAGMLGNFQQESSMSPTAIER
                     PNDPLSGHGIAQWTAGRTTALKNFAKERNKEWSDLGVQVEFLIHELNTTEKASQVALQ
                     AKSVEEATEQWQVKFERAGIPMMGNRITFANQWYAKLGKNDSDPVASITLENGANAGS
                     KDLTDYCLETTGTSSSSDSNVLNVAKSLIGYFHYSQPQRAQFGSVENPDKNGYADCSS
                     FVWLVLTKAGYKTPANVGWFTGSMTSDARGSKQYLQEIPESEAKAGDIIIVNLGSGVG
                     NDGHTAVLAEDWHGLSTKVIEQGGMNTNGVGEGQVNLSFGYLLNGGDICFARPIKK"
     gene            complement(2126..2998)
                     /locus_tag="IXR05_002706"
     CDS             complement(2126..2998)
                     /locus_tag="IXR05_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4261150.1"
                     /translation="MKKMILGSLFSATVLLGMVGTSAYADTTSPGDPSVPPTEIIPPT
                     EETPEVPEEPVLPPTDGGEETPEIPEIPETPETPEIPPTEENPDTGGGTETPEVPENP
                     DTGGGEGTPEVPPVEENPGNGGNTETPEKPSNPGGNEGNTTPPTTPPTNNGGTNTTPP
                     VQDVVVKPDGSIGSQQTGGQNVQIETNNASELTHIPTPSTPIETASGEKIVSVVDGVA
                     YKESGNGLTPISDKVEQLPSGNIAVKGSDGKMKVLPKTGEEVSLVATALGGLLASGSG
                     FAFWRKRKATQKMN"
     gene            complement(3020..3940)
                     /locus_tag="IXR05_002707"
     CDS             complement(3020..3940)
                     /locus_tag="IXR05_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261151.1"
                     /translation="MMMIRFTEVDNMSLLTDKKIALDKAFIQLKRENEELLARAEIGW
                     CTLEIYTENHEIPVFEGSYDFPVEEFHLISLIEQSLTENGQLSEEAQTFIQTLNSELP
                     KFYQVKKDQKNERRPTKIKKEKKTPLSVETAFTQSNGSLQKKKMSFQWLLFGFIVVVS
                     CGLFIMQLSTQREIEQLTKKEHQLQERIAFAEELATKQPQIDTFSRYFITNYYSGEMA
                     EERYRKKLQSFLTEKVAKQISPQKEKVKSILSWEMKKEGKHWQIAYVITLETEKKTQE
                     TKKVSFQLEEQEKNYLVSTLPELDDFEINQ"
     gene            complement(3940..4209)
                     /locus_tag="IXR05_002708"
     CDS             complement(3940..4209)
                     /locus_tag="IXR05_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261152.1"
                     /translation="MIIVTGIVLLGIGVLFGYHFAYFPKIGEWQQRQAIQKYFQVKGN
                     EYTYYAEDEDSYIVSLNNQEYRVKFSLNNPIQVVYAVEVVEEVFD"
     gene            complement(4206..4586)
                     /locus_tag="IXR05_002709"
     CDS             complement(4206..4586)
                     /locus_tag="IXR05_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HAQ4261153.1"
                     /translation="MITNYKKFWQNSFNYKGKATRKEYWLVALMNALIGFGLGLAIGL
                     AGALNASETIIGCLIGVLIVYCFVVLVPSLSLSVRRLRDAGFHWAFIFFYFVPTIGSL
                     VLLVLYCLPTKESIEDKQVQEETR"
BASE COUNT         1253 a         1050 c          790 g         1692 t
ORIGIN      
        1 caaaaaggca agtgcttctt tgtaggcatt ttgactgtat ttttttgata aagcatgaca
       61 aatttcttga taaaatagtt gactgcctac cgaataccga ttattgtgta tccgccacaa
      121 aacgaacaca ctgatttgaa tcgacgggcg taaaaaagaa aaattctttc cataagaaaa
      181 agaacgtcct tcttgggttt cttttgcttg ttctgttggt acttcttgta cctctcttat
      241 tgattcttgt ctctccataa ccttctcctt ttcttattct tctaaaagct gttgattaaa
      301 gctacttccc aaattttgca taaacgtgat tttctttgac gctggatcaa aggttacgtc
      361 aaaaatattc atggcattat tccaggaact atcaccaatt ttattgcgat acgacaccac
      421 aacgagccct tggatagtcg ctttttgtgt gctttttaaa taaacagaac atttctctaa
      481 ttcagaagac accccgtttg aatcaccata ggaaacgcct tctttgaaat attgcttcat
      541 cagtttgtca gaaagatatg gtgcacaatt gttttttcgt tcttgaaaag aatcaggctc
      601 ataattaaac agaacctcga acgcttctgt cactgttttt tgaaaggttt gaatgtttcc
      661 tttttctgtt gaatcattgt ttttcaattc ttcatttgct ttttttaacg tcgtgacctc
      721 gctttctact tgttgaagtt gttctttgag tgacgttaca aggtcttcct gtcctttctt
      781 ctcttcttgg aacttgttta tctccaccgt cagtttctct tcctttgctg ttagctgtag
      841 cttttcatga ataagaaaaa atgtactgcc tacaccaaat aagaacaatc cgcctacaca
      901 aacataaata aatcgtttct tcatttgaca cctcttattt ctttatcggt cgagcaaaac
      961 aaatatcacc accattaagc aaatacccaa aggataaatt gacttgccct tcacctacac
     1021 cgttagtatt cattccccct tgttcgatta ctttcgtaga aagtccatgc caatcttccg
     1081 ctaaaacagc tgtgtgtcca tcatttccca caccagaacc taagttcaca atgataatat
     1141 cgccagcttt tgcctcgctc tcaggtattt cttgtaagta ttgcttactt cctcttgcgt
     1201 cgctcgtcat tgagccggta aaccacccaa cgttcgcagg cgttttatac cctgctttcg
     1261 ttaaaacaag ccacacaaag ctcgaacaat cggcatagcc atttttatct ggattttcga
     1321 cactaccaaa ttgtgcccgt tgcggttgtg aataatgaaa ataaccaatc agactttttg
     1381 ctacgtttaa tacattacta tcggaagaac tgcttgttcc tgttgtttct agacaataat
     1441 cggtcaagtc tttacttcct gcgtttgccc cattttctaa tgtaattgaa gcgacgggat
     1501 cactgtcatt ctttcctagt tttgcgtacc attgattcgc aaaagtaata cgattcccca
     1561 tcattggtat ccctgcacgc tcaaatttca cttgccactg ttctgttgct tcctctacgc
     1621 tttttgcttg taatgcaact tgtgaagctt tttctgttgt gtttagttca tgaatcaaaa
     1681 actcaacttg tacacctaaa tctgaccact ctttgtttcg ctctttggca aaatttttca
     1741 aagcagtcgt tcgccctgcc gtccattgtg caatcccatg cccagataat ggatcgtttg
     1801 gtcgttcaat cgctgtggga ctcatactcg actcttgttg aaaattgcct aacatacccg
     1861 ctagaccctc taatgtcgta tttggaatat gtttttgtac ttcctttgca atttgaagcc
     1921 cgtttgtctc catgccttgg ttcgttaatg agatagtact tgcgacaatt tcggttggac
     1981 tacagtcgat ttcttcctct tcagaaccac tactaatcaa aagtatcata aacagaaaac
     2041 caaacataca tagtaatagt gtgggtagac aaccgaaccc acaccataaa agaagttttt
     2101 tcttcatgtt tgatccttca ttcgcttagt tcattttttg tgttgctttt cttttgcgcc
     2161 aaaaagcaaa accgcttcct gaagccaata atccaccaag tgctgtcgca acgagagaca
     2221 cttcttcgcc agtcttaggc aatactttca tttttccatc agaccctttc accgcaatat
     2281 ttccgcttgg aagttgttcg accttgtctg aaatgggcgt caagccattt cctgattctt
     2341 tataagcgac accatcaacg acggagacaa ttttttctcc tgaagctgtt tcaattggtg
     2401 tacttggtgt tggaatatgg gttaattcag acgcattatt ggtttcaatt tgaacatttt
     2461 gtccacctgt ttgttggctg ccaatacttc catctggttt tactacgacg tcctgtactg
     2521 gaggcgtagt gttcgtcccc ccattattgg taggtggtgt cgttggagga gtcgtatttc
     2581 cttcattgcc tcctggattc gacggctttt ctggtgtctc tgtattacca ccatttcctg
     2641 ggttttcctc aacgggtgga acttcaggtg ttccttcccc tccgccagta tctggatttt
     2701 ctggtacttc aggcgtttct gtgcctccac ctgtatctgg attttcttcc gttggtggaa
     2761 tctctggggt ttcaggagtt tctggtattt cgggaatttc tggggtttct tctcctccat
     2821 ctgttggtgg taaaacaggt tcttcaggaa cttcaggtgt ttcttccgtt ggtggaataa
     2881 tttctgtcgg tggtacactt ggatcacctg gtgacgtagt atctgcatac gcactggttc
     2941 ctaccatacc tagcaataca gttgcactaa ataaacttcc taaaatcatt tttttcatgt
     3001 gtttttcctc ttctcttatt tattgattta tttcaaaatc atctagttcg ggaagcgtgg
     3061 aaactagata atttttttcc tgttcttcca attgaaaaga cacttttttt gtttcttgtg
     3121 tctttttctc ggtttccaat gtaatgacat acgcaatttg ccaatgcttg ccttctttct
     3181 tcatttccca ggataaaata cttttgactt tttccttttg aggactgatt tgtttcgcaa
     3241 ctttttccgt tagaaacgat tgaagctttt tcctataccg ttcttctgcc atttcacccg
     3301 aataataatt cgtaataaaa taacgactaa atgtatcaat ttgtggttgt tttgtcgcaa
     3361 gttcttccgc aaatgcaatg cgttcttgta actggtgctc ctttttcgtt agttgttcaa
     3421 tctctctttg cgttgaaagt tgcataataa aaagaccaca agatacaacg acgataaatc
     3481 caaacaaaag ccattgaaaa gacatttttt tcttctgaag agagccgttg ctttgtgtaa
     3541 acgctgtttc tacagaaagt ggtgttttct tttccttttt gatttttgtt ggtcgacgtt
     3601 cgttcttttg gtctttcttt acttgataaa acttcggtaa ttcggaattt aaggtttgaa
     3661 taaaggtttg tgcttcttca cttaattgcc cattttctgt taaagattgt tcaatcaatg
     3721 aaatcaaatg aaactcttct actggaaaat catacgagcc ttcaaatact ggaatttcat
     3781 ggttttctgt gtagatttcc aaggtacacc agccaatttc cgctcgtgcc aatagctctt
     3841 cattttctct tttcaattga ataaatgcct tatctaatgc aattttttta tctgttagta
     3901 aagacatgtt atcaacttct gtaaatcgaa tcatcatcat tagtcaaaca cttcttccac
     3961 cacttctacc gcatacacca cttgaatagg gttatttaaa gaaaatttca cccgatattc
     4021 ttgattgttc aaactgacga tatagctatc ctcatcttca gcataatagg tatattcgtt
     4081 gcctttgact tgaaaatatt tttggatcgc ttgtctttgt tgccattcgc caatctttgg
     4141 aaaataggcg aaatgatagc caaataaaac gcctatccct aataaaacaa ttcctgttac
     4201 tataatcatc tggtttcctc ctgtacctgt ttatcttcta ttgactcttt tgtcggtaag
     4261 caataaagaa ccagtaacac aagagagcca atcgttggga caaaatagaa aaaaataaat
     4321 gcccaatgaa aacctgcgtc tcgtaaacgt cgaacgctga gagaaagaga cgggacaaga
     4381 actacgaaac aatacacaat caatacgcct atcaaacaac caattattgt ttcagaagca
     4441 ttcaacgctc ctgctagtcc aatcgctaag cctaggccaa acccaatgag ggcattcatt
     4501 aacgcaacga gccaatactc ttttcttgtg gctttccctt tgtaattaaa gctattctgc
     4561 caaaattttt tataatttgt gatcatatct ttgtcctttc taatgtttat ttttgattct
     4621 agtttcttct gttttactaa caatgaaact tgccataaaa aaggtggcca atacaccacc
     4681 agctagaaat ccacttacaa ataacaaaat tttttcctcc tttctaaaaa atttcgccat
     4741 aaaaaggcaa agtatgaaca cgataaatac catgtacata ctttg
//
LOCUS       DACGDM010000142         4710 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.150, whole genome shotgun sequence.
ACCESSION   DACGDM010000142 DACGDM010000000
VERSION     DACGDM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.150"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            106..357
                     /locus_tag="IXR05_002710"
                     /pseudo
     CDS             106..357
                     /locus_tag="IXR05_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            450..1244
                     /locus_tag="IXR05_002711"
                     /note="aph(3')-IIIa"
     CDS             450..1244
                     /locus_tag="IXR05_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAQ4261154.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1654..1765
                     /locus_tag="IXR05_002712"
                     /pseudo
     CDS             1654..1765
                     /locus_tag="IXR05_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            1786..1869
                     /locus_tag="IXR05_002713"
     CDS             1786..1869
                     /locus_tag="IXR05_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HAQ4261155.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            1994..2731
                     /gene="erm(B)"
                     /locus_tag="IXR05_002714"
     CDS             1994..2731
                     /gene="erm(B)"
                     /locus_tag="IXR05_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAQ4261156.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(2994..3857)
                     /locus_tag="IXR05_002715"
     CDS             complement(2994..3857)
                     /locus_tag="IXR05_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAQ4261157.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTP
                     PIPKTPKLPGI"
     gene            complement(3859..4131)
                     /locus_tag="IXR05_002716"
     CDS             complement(3859..4131)
                     /locus_tag="IXR05_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4261158.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            complement(4148..4363)
                     /locus_tag="IXR05_002717"
     CDS             complement(4148..4363)
                     /locus_tag="IXR05_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAQ4261159.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(4455..>4710)
                     /locus_tag="IXR05_002718"
     CDS             complement(4455..>4710)
                     /locus_tag="IXR05_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /protein_id="HAQ4261160.1"
                     /translation="IGFVPYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVS
                     TWSKNGITEHKGYDKKVLSMYKNVFFEMLERIIQLENEKE"
BASE COUNT         1445 a          796 c          865 g         1604 t
ORIGIN      
        1 ttcttgggag ttttgagact actatatgcg tttttttgtt gatttaccaa catgtttaga
       61 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
      121 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      181 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      241 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      301 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      361 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      421 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      481 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      541 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      601 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      661 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      721 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      781 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      841 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      901 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      961 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     1021 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1081 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1141 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1201 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1261 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1321 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1381 cgcctacgag gaatttgtat cgataagaaa tagatttaaa aatttcgctg ttattttgta
     1441 catttaactt gacggtgaca tctctctatt gtgagttatt agtggtacag ttttcaaccg
     1501 ttttaattat aaaaaagtgg tgcattttta aattggcaca aacaggtaac ggttattgca
     1561 ggtgtatttc ttatctatgg gtttaacatg gattttatca ttaaaatcat gagtattgtc
     1621 cgagagtgat tggtcttgcg tatggttaac cctaaagtta tggaaataag acttagaagc
     1681 aaacttaaga gtgtgttgat agtgcattat cttaaaattt tgtataatag gaattgaagt
     1741 taaattagat gctaaaaatt tgtaattaag aaggagggat tcgtcatgtt ggtattccaa
     1801 atgcgttatg tagataaaac atctactgtt ttgaaacaga ctaaaaacag tgattacgca
     1861 gataaataaa tacgttagat taattcctac cagtgactaa tcttatgact ttttaaacag
     1921 ataactaaaa ttacaaacaa atcgtttaac ttctgtattt gtttatagat gtaatcactt
     1981 caggagtgat aacatgaaca aaaatataaa atattctcaa aactttttaa cgagtgaaaa
     2041 agtactcaac caaataataa aacaattgaa tttaaaagaa accgataccg tttacgaaat
     2101 tggaacaggt aaagggcatt taacgacgaa actggctaaa ataagtaaac aggtaacgtc
     2161 tattgaatta gacagtcatc tattcaactt atcgtcagaa aaattaaaac tgaatactcg
     2221 tgtcacttta attcaccaag atattctaca gtttcaattc cctaacaaac agaggtataa
     2281 aattgttggg aatattcctt accatttaag cacacaaatt attaaaaaag tggtttttga
     2341 aagccgtgcg tctgacatct atctgattgt tgaagaagga ttctacaagc gtaccttgga
     2401 tattcaccga acactagggt tgctcttgca cactcaagtc tcgattcagc aattgcttaa
     2461 gctgccagcg gaatgctttc atcctaaacc aaaagtaaac agtgtcttaa taaaacttac
     2521 ccgccatacc acagatgttc cagataaata ttggaagcta tatacgtact ttgtttcaaa
     2581 atgggtcaat cgagaatatc gtcaactgtt tactaaaaat cagtttcatc aagcaatgaa
     2641 acacgccaaa gtaaacaatt taagtaccgt tacttatgag caagtattgt ctatttttaa
     2701 tagttatcta ttatttaacg ggaggaaata attctatgag tcgcttttgt aaatttggaa
     2761 agttacacgt tactaaaggg aatgtagata aattattagg tatagggcac ctctaataac
     2821 taccaattaa ttcacctcaa aatgaaatta gaaaaaaaca gcgaaatttt taaatctatt
     2881 tcttatcgat acaaattcct cgtaggcgct cgggacccca acatgaggaa atgtttttat
     2941 aaaaaaagag tagttaccgt tttttggtaa ctactctttt ccttttttaa ggtttaaata
     3001 cctggaagtt taggtgtttt gggtattggt ggtgtaggtg gctgcaagct ttccaatttt
     3061 tgttgaattg ctttaaattc aggtgtctct tggtgtttat ttagaaccat tttttgctct
     3121 attcgttcta aagtcggttg aatttctttc cctgatactt tacgattcaa ttctttttct
     3181 aaggtttctt ttggactaat agaaggtgtt tccaaacttg aatagagttt tactccttct
     3241 ctgttatata gccttatatc gctaaataag cccgttttat gaagggtttc taaattggtc
     3301 ggtaagtttt tgacaacaat atcatgcgct tgttttggtg ttgccctggc tgtcattgga
     3361 tcatctgcat acatggtttc atatcgttca attgttccta aatatgagtt gattttaggt
     3421 actgccatga catacatttt tgtttcataa cctttggctt gaagcattgt tgcggtttga
     3481 ataggaacgt ctgttgttcg tcctgtacct tcgatcacca aattataccc ttgatcgctc
     3541 aaacggctta tgatcgcttc tgtcatgcga ttagaataag gggtaacgtg ttttactacg
     3601 tctttttcat aaagtttcac tagttcatca aaattagggt gctgttgttt aaaggtatca
     3661 ttatcaatga caataacatt cccttgtgtt tcttcaaaaa ttgctgatcg caaactggtt
     3721 ttccctgacc ctggttgccc accaagtaaa aaagcggttg gcgattcaac cgcttttttt
     3781 ccttgaatca attcttctaa attatcattt aagcgattct caaattgttt gtcagtaaaa
     3841 ttgactatat ttgccatatt aagccacttt ctctttattc aaaacttgtt ttgagtaacg
     3901 attcattgac cgccaatact catgaacggc ttgtaattct tctaaagaat aatcaaaaag
     3961 atttacacgt tttgcaagct ttaattggtt taataaattg acttccaata attgagagtc
     4021 atttttattt aattcatggt tcaaaacata gtttaatact cgattataaa cgcttgccga
     4081 taattcgtta atgatctcta tttcaaatgt tttttcatac gtaactgcca tttcattttc
     4141 actcctttta aagtttgtca ggtaaatatt tccgtatata ttcttctaag gcttgatcca
     4201 taacttcttt tacgtttccg ccattctttg ctgtttcgat ttttatgata tggtgcaagt
     4261 cagcacgaac acgaaccgtc ttatctccca ttatatcttt ttttgcactg attggtgtat
     4321 catttcgttt tgctttttgt gcgcctaaat ttcccacaat cactcacttc tttctatttc
     4381 ttcttactct tattttatca tcaacaatca caaatcacaa gtgatttgtg attaatcact
     4441 tgtgatttgt gattctattc tttttcgttt tctaattgaa taattcgctc aagcatttca
     4501 aaaaatacgt tcttatacat ggataaaact tttttgtcat agcctttatg ctctgtaatg
     4561 ccgtttttag accaggtact tactttatta cttcgcttga taatattttg gaaaaccaag
     4621 ttatcttctt tatgttgctt atacagttct tccaggtttg attttatcgt tgcgctgtcc
     4681 gtatcaacta aataaggaac aaaaccgatc
//
LOCUS       DACGDM010000143         4634 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.151, whole genome shotgun sequence.
ACCESSION   DACGDM010000143 DACGDM010000000
VERSION     DACGDM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.151"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            174..518
                     /locus_tag="IXR05_002719"
     CDS             174..518
                     /locus_tag="IXR05_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAQ4261161.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            519..938
                     /locus_tag="IXR05_002720"
     CDS             519..938
                     /locus_tag="IXR05_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAQ4261162.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1030..1380)
                     /locus_tag="IXR05_002721"
     CDS             complement(1030..1380)
                     /locus_tag="IXR05_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261163.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1346..2566)
                     /locus_tag="IXR05_002722"
     CDS             complement(1346..2566)
                     /locus_tag="IXR05_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAQ4261164.1"
                     /translation="MLSNTPTDNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILT
                     LLSVLLAYRHKVILNGPLFASILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQ
                     YIMIGLFGSALSPVVSYITFGMRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGF
                     TLYNIGFTSGLIAMTFTAVLRLFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFY
                     YNSFRLLGIREIFDSSGKLTTDFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPV
                     IGAILSAVGFSAFGCHLKNSFPILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPIS
                     GFYGSFYGVIAGVLHIALVHNVSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKE
                     KKTLGKRIIKKNHR"
     gene            2932..3498
                     /locus_tag="IXR05_002723"
     CDS             2932..3498
                     /locus_tag="IXR05_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4261165.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3643..3730
                     /locus_tag="IXR05_002724"
     tRNA            3643..3730
                     /locus_tag="IXR05_002724"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3675..3677,aa:Ser,seq:cga)
     gene            4064..>4634
                     /locus_tag="IXR05_002725"
     CDS             4064..>4634
                     /locus_tag="IXR05_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAQ4261166.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         1684 a          778 c          891 g         1281 t
ORIGIN      
        1 aaataaaaaa agcgttagca actatgctta aaaagcatat cgactgaata aactaagcat
       61 tggacaggct gaaagactac atttaaaatg aaatgcgaag aaacaataga aaataaagtt
      121 gccttagaac catagttgaa tcacctaaca gtcgtgaagg gagaataaga gaaatggcag
      181 aaaaacaaac cgcaggacga gatcaattag gagattttgc accaaaattt gcagaattga
      241 atgatgatgt tttatttgga caagtatggt ccagagaaga attatctgct catcagcgta
      301 gtatcatcac catatctgca ttaatttcag gaggaaattt tgaacaattg ccagctcatc
      361 tgaagattgg caagcaaaat ggcattacta gtgaagaaat agcagaaatc attacccatt
      421 tagcttttta tgtaggatgg ccaaaagctt ggtcagcttt tagtttagca aaagaaatct
      481 atttagaaga aaatagcgaa gataagaaag aggcgtaaat gacgacaaaa cacgaagaaa
      541 tacacaatgg cgtgattttt ccagcaggtg aaaaaaacga agcttacgct caagtattta
      601 ccgggcaaag ctatctgaat atgttagtga atgatcccga agtttctgtt ggtgtaggta
      661 atgtaatttt tgaaccaggt tgtcgcaatc actggcatgt ccataaagac ggctatcaaa
      721 tcttacttgt gaccggagga gaaggctggt atcaggaaga aggaaagcca gcaagacgat
      781 taatggctgg agatgtcgtc gtaacgcaca aagggattaa acattggcat ggtgcgacaa
      841 aagacagttg gtttgaacat ttggcgatca ctgctggtaa ttcagagttt ttagaacctg
      901 taacagatga agtgtatgaa ggattggaaa atcaataatg tcaagcttga acagctcctg
      961 aaagtagatt ttaatcgaac tttcaggagc tgcttttttg attcagtctt ttataaatag
     1021 aaaatagggt taataatagg aatgagaagc acgtcgaaag atcttaatat tgataatcgg
     1081 ctgggcatac atgatttcca cgtcatcaat caaactacct aacagatgat aatcttcccg
     1141 atcatgtcgg ggattaccta atagttcttg atagtagatt tccatactag ggtcccgagg
     1201 attgttcagc aaatcagcaa gtacatctaa atcttctggc tgagtttctg ccgtaccctg
     1261 tatctctatg aaaagccctt cctcagcaaa ttctactcca atacgtattt cagttatttc
     1321 atgggaatat aaataagtaa gaagctcatc gatgattctt tttgataatt ctttttccaa
     1381 gtgtcttttt ttcctttctg acagcggtaa agttatctag tatcggtaca aggatacctg
     1441 caacgaaacc agttgaaaaa ccactgttat atagatttag tcctccgtgc aaagtgctga
     1501 cgttatggac aagagcaata tgtagtacac cagctattac accgtaaaaa ctgccgtaaa
     1561 aaccgcttat gggcgcgaga cctgtcccaa acacagctgc aacaagcatg ccagtactgg
     1621 tgatctcatg aaaagttcca aacaaagaag caataaatat tccgactagt atcggaaaac
     1681 tgttttttaa atgacaacca aaagcactga aacccaccgc agataaaata gcaccgatga
     1741 caggtccatt taactgaccg ccaaccagca aaacataaga agacagcatc agaccaacta
     1801 agcctatgtt gatcaaagta gcaccaatac cagaattagc aatgaaatca gttgtcaatt
     1861 ttccagatga atcgaaaatt tctcgaatcc ccaaaagccg aaaggaatta taatagaaac
     1921 caattccgac tgtcagcgaa aaaaagccaa aaataatcca aatgagagga aagtgatatt
     1981 cattgaaaac caatgtattt tcgacgattg aatagctgaa taacctcaaa acagcagtaa
     2041 aagtcatcgc aatcaaccca gaggtgaatc caatattata aagtgtgaat ccacgatgga
     2101 aaactaaagt ttgagcagct aagggcggaa gaagtagacc aattgctatg ccagctaaat
     2161 tccccaataa aatacctatc agtaaaggaa aacgcatacc aaaagtgata taactaacga
     2221 ccggtgataa tgcgctacca aacagtccga tcatgatgta ctgagaaaaa ggtttattga
     2281 caaatacagc gtatagatac acacctaaaa tgattgagat agaattataa aggtttttgc
     2341 caaaaaaaga gaaaccggta actgttagaa tcgaagcaaa taagggaccg tttaaaatca
     2401 ccttgtgccg ataagctaaa agcacagaaa gtaaggtcaa aatccctaca tttatgaatg
     2461 cgcttccgaa accgcctaaa gcaaaataat ctgtcaaaag attgcttggc gaggtaagaa
     2521 tagttagcaa tccactccaa ttatcagtag gagtattaga aagcaagcca ataaaaagaa
     2581 aaaaacacct gtaaaaccaa gataaaaata ctttcttttc tgtgaaacga ttcgtttttg
     2641 aggatgaata taaataacgt cagtttcgtt ttccattaca caccttcttt ttcattttct
     2701 ttaactataa cttgaaatga aagatttgga caactatcat ttaggtcaaa actaaaaatg
     2761 taagggaacc cattgaattt aaccaaattt ttttaatttt gcaaaaaaaa gttaaagaag
     2821 actgaaaaaa aatttaaaat ataacgtttt gagtaaaatg tttgcaaaaa atgctaaaaa
     2881 tagggtacaa taaaacaaca tatactgcag taaagaagtg ggggagtttt aatgagaaga
     2941 aaagtctata ccaaggatca aattctaaaa gctgcttatg atgttgttgc aaaggaaggg
     3001 tttaaaggat ttactgcgag aaatattgct aaaaagatgg ggatttcgac acagccgatt
     3061 tatctggaat tcaaaaacat ggaagattta aaaaatacgt tgctggattc tatctttgaa
     3121 caactaaaag aagatgtttt ccctattgaa cgtactggtg ataaaatcat tgatctcggt
     3181 ttgaactata tctactttgc aaaaaagcat catagtcttt acatggcatt gtacattgat
     3241 gaacatgggg acggaaagaa aatgcatgat ttttcataca attatttccg tgaaatagtt
     3301 aaagaagatg aaagatacaa tcaattatcg gatgaatatg tcgatgctct gcatactggt
     3361 acatgggtag cagtgactgg cttagcgtca ttgatgtcat caaacatcat gcatccaaca
     3421 gaagaacaaa tcattgcact gatcaaacgg acaattgact cgattttagc attagataat
     3481 cctgaaataa tcagatagtg ttctatcagt atgaatttga tcggtaagtc cgttggctgc
     3541 aaactgtcaa tggacttttt tgctaaaaaa agcgatttct gttatttatc tattagaaat
     3601 aggcttgaca tttcgtgaaa aaagtttaaa aatagtactt acggaaggtt ggcagagtgg
     3661 taatgcaccg gactcgaaat ccggcgaacc ggctaatacc ggcgcgcagg ttcaaatcct
     3721 gtaccttcct tatatcaacg attagaggtt gtgaagaagc tgtcctgcat caagtaataa
     3781 gaacggccaa acaaaaatag cttttcctat tttttcgttt gattgggctt attaccgcag
     3841 atgcaagctt ttgaacaccg tttgttcgga ataaggggct gtgacaagac ttttgtcaca
     3901 gccccttatt gttgtacttt taacctacaa tattttttga ttccccctga gtactatttt
     3961 ttataaatgc tagtaaatca atcttctttg gccttttttt gataaaaaaa atactagatg
     4021 taagataaaa gtgtaaaaac gatttgtttt aggaggggaa acgatgtgta ccgcaatcac
     4081 ttatgcaacg aaagaccatt attttggaag gaattttgat tatgagatgt cttataatga
     4141 agtggtcact attactccaa gaaattatcg tttcgatttt agaaaggtaa aaaatttaga
     4201 taaacattat gcaatgatag gaatagcagc tggggtatcc aactatccac tctattatga
     4261 ggctacaaat gaaaaagggt tgagtatggc aggactgaat tttcctggca atgctgatta
     4321 taaagaatta caagaaggaa aagataacgt tgcaccattt gagtttattc catggatact
     4381 agggcaatgc tcaaccatag acgaagctaa agaattattg gctactatca atctagtcaa
     4441 tatcgatttt agtgaaaaac tacccttgtc acctttacac tggttattag ctgataaaga
     4501 aaaatcgata gtaattgaaa gtatgaaaga tggacttcat ttatatgata atcctgtcgg
     4561 tgtgttgaca aataatccgc catttgatta tcaattattt aatctgaaca attatcgctc
     4621 gctatcaaat ggaa
//
LOCUS       DACGDM010000144         4611 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.152, whole genome shotgun sequence.
ACCESSION   DACGDM010000144 DACGDM010000000
VERSION     DACGDM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.152"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(86..340)
                     /locus_tag="IXR05_002726"
     CDS             complement(86..340)
                     /locus_tag="IXR05_002726"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4261167.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPIMDRLQLTRQKN"
     gene            complement(451..705)
                     /locus_tag="IXR05_002727"
     CDS             complement(451..705)
                     /locus_tag="IXR05_002727"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4261168.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(898..1173)
                     /locus_tag="IXR05_002728"
     CDS             complement(898..1173)
                     /locus_tag="IXR05_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAQ4261169.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1145..2098)
                     /locus_tag="IXR05_002729"
     CDS             complement(1145..2098)
                     /locus_tag="IXR05_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4261170.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2710..4203
                     /locus_tag="IXR05_002730"
     CDS             2710..4203
                     /locus_tag="IXR05_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAQ4261171.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4338..>4611
                     /locus_tag="IXR05_002731"
     CDS             4338..>4611
                     /locus_tag="IXR05_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAQ4261172.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELR"
BASE COUNT         1492 a          774 c          802 g         1543 t
ORIGIN      
        1 ttgcttgaat tcttgtgaaa aagttcttcg tgttctctta gacataaaaa ttcctcctgg
       61 tatgttttct tctagtctac acaccttaat ttttctgtct agttaattgt agcctatcca
      121 tgatcggttt attagacctt tgaggtctat attttttaac tacaatcgac cttaaattta
      181 attgtttcat tagcttttgg acatgtttaa gagatactga aatcccttct tttaataaaa
      241 cttgatggat ctttgtggca ccatagcgtt gtttattcgt aaaaaaaatt gttgaaatct
      301 tctttttcaa cttattattt ctgatttctg tagctgtcaa cggtttattc ttataaaaat
      361 aatagacact tctagggatt tctaataacc gacacaacaa agaaacagtg taatccttac
      421 accatttttc aataaattga acaagcgaat ttaggttttc cgagagaata tggctgcggc
      481 tttttttaag atttcaagtt cctcatttaa acgagcattt tcttttctca gttcagctac
      541 ttcttttcca gtcagtcctg tggactgatc aggtaaatat aaattcttcc atttgtaaat
      601 cgttgcttca gataagccat attctttcgc taaccctcga acagaacgtc cagtttgatt
      661 cagttcaaca atcatttgtt taaaattttc ttcatatcgg gtcataaaaa ttcatcctct
      721 cgtagataag tttaatttat tcttgtctct acgaaaagct gtctaagatt tgatactaac
      781 accaaatgtt gtataccccc aaacaataca catattttga aggattagga ttaataaagc
      841 taaaaatata gtaagtatac taaatatatt tactatatct agtatactta ctatatttta
      901 atcttttgat cgtctattat atataatccg ttcctcgtcg tttaaagtat caacataggc
      961 gtccattgca agtttgacta tttcatacat aggaatatct tttgcataac taagatcccg
     1021 aatggttttt agtacgggag gatctacttg aactggtttt ctttctttcg cagtgtactt
     1081 tcgttcccct aactcgacat taatatcatc tttaattgaa atatcttcag caccaatttt
     1141 cttcttatct ttgttcgttg gtaataatgc catttagttt aatctccttt ccaagaggta
     1201 ggatatgatt ggccattgag tcagcatatt taggtgtata atcaaatcct tcaatatcac
     1261 catgttgttc atagtattca attctttctt ctaattctgt aaagatgtct gcaaaaatag
     1321 cccaccatct tcgatctaca taatcattta attggatacc attctcacca tacatttcta
     1381 accgatccga gcctttaaca atgcttttaa aaatgtttga ttcaccatac ttatcaattg
     1441 ttttttgata gtttgcgtgt tgagaggaac gtcgcactga gaaaagaaca ggcaaaattc
     1501 caatgatttg aagatgagac tcttcaaaat tcgtgacaat cggaactaaa actttattaa
     1561 taaaatcttc tgttccttcc attgcgtacc gttttaattc ttgcattgca ataatataat
     1621 ctgcagcagt taagaatgca cgaaccacat tatctgttga tggtgggcag tcgataaaga
     1681 tataatcgaa attttttctc aattcttcta aaggtttaat gaaggccaat gatctcttac
     1741 gacgatcagg atatttttcg gacaagtatt cattaagttc ttcagatcca ggagagccag
     1801 ccataatata taaatgtgga cttacttgag taatacctga aacccagtcc ccttttttga
     1861 ttgctgcaga catggatcga tcaaagctag taatttgata cgttgatcca atgttggaag
     1921 tagtatttct ttgttggtca taatcaatta gcaacacgtc tttttcaaaa agttgactag
     1981 aaacaatcgc taataaatca ttgtctgtag tcttaccaat gccgcctttt ctacctgtaa
     2041 gcattacaac ttttcctagt ttatctgatg ttttaaatgc agtccgtaag ttttccatag
     2101 ttccctccaa tttcctatac taaatatatt tagtatactt catatactta atatattcga
     2161 tatatctaat atactccaaa ttgataagaa ttcagacttt ataaggaata tagtggatat
     2221 actaaatata tttgctatat tcagtatatc agatatattc aaaatgtcaa aatatatttg
     2281 tgcgttttgc gttgacaatt tagagtgaaa agaggtaaac ttaattctat agaaaccaca
     2341 gataattcac tatttacaaa gtagcaaaag cagtggtact ctttaaacag aaaaattaca
     2401 taaaaaaaag agacggaaat aattgatttt agcagaatca attatttctg aatcacatgg
     2461 ttaggacatg tgttcacgct cgtctcaaga atatgtaagt agctaccaac tacttatatt
     2521 aaaagttgat cggatacctt ttccgattgc ctttattcta ccaaaaaaag gcgagcaact
     2581 caacagaaga acgtttattt agtgtactta aattaaatat tcttaaacac tgaagagaga
     2641 acacatacta tggctgagat taaagctaaa ctgtgttctc tttttgtttg agaaaggacg
     2701 ttacaatcga tgttgagcga aatttattca gctattctta aaaacggctt acgtacatac
     2761 aaatatcgaa acagcaccat gaaacctgca ggtcatattg attccagtag gagtggtgct
     2821 atctttgcgt accgtagcaa gcaattaatg aatgttgggc gtggtatggt cattacttcg
     2881 gaagaagcta ttttagagaa cgaaaagaaa ctaacgcatt ggacacctaa tacctatcgc
     2941 tttggtactt atgcggatga ttatcgaaca gtggttaaag gtcattctga gaaaaactta
     3001 agtcaaatca acacatttgt agttgatatc gattcaaaag agaaccatca aggcgaaatt
     3061 attttagcct gtttagatca agtgggctac atgccaacgc taattttaga atcagatcat
     3121 ggttatcaag tttattttgt actaaagaca ccaggctatg tcacaaagaa aagcaatttc
     3181 aaggtgatcg atgtagcaaa aaaaatttca aaaacaattc gtctacagtt ggctgaaaaa
     3241 ttgtccggag tggatctagg atgtaaccac ttcggaattg ctcgattccc acaagaaaat
     3301 aatattgttt ttaaagaaat gaactatcag tattcttttg ctgactggat tcaatggtcg
     3361 atgaagcttg aatcagatca aaaaacaaaa gaagatcgag aacgaaaact aattgtcttt
     3421 cctgagaaaa aagaaattcg tcaagtagat gaaccgtggt tcgatatgtt acttcataaa
     3481 gcaaacatcg tcggcggaga aggacgtctt ggtcgaaata atgtgatttt cacgctttct
     3541 ttagcttatt actcttcagg ttatgcattg gatacttgcg aatacaatat gttcacattc
     3601 aacgaacggt tacaggaacc gctatctgaa gcagaattag taaagattgt acgtagtgct
     3661 tattctggta attatcaagc agcaagcaga gaattcatta ttgaattgtg ccagcaatgg
     3721 gtttcaccaa ccttaaaaaa taatgatctg ttcattcaac gacgtggctg gtggaaattt
     3781 aaaaagccac gagatcaaag aaaatatagt cataaaaatg aatggaaaga agatctattg
     3841 gcttatctaa gcgaaaaaag tcttgctagt gagccttatt tgaacctgtc aaaaaaagaa
     3901 ttggcttcac aactaacgat gcccaagcga acacttgata agatcttaaa tgagttacga
     3961 gaggagaata aagtcttcta caaggtaaca cgaggaagaa atggcggaat gatcattgct
     4021 tcagtcaaaa cgttgttcgc gagggttatt caactaagta aagaaaagag actagattat
     4081 tcaacaagga tcacagaggt atttggactc aacgagagct tagtagaaga gacatttaga
     4141 caattatcaa cccccttgaa ccctcttaaa gaagtgaatc tttttgaagt agatacaggt
     4201 tgaaaaataa aaggtgcaaa ttgccttata caatatatct atgatacttc tgtaggtgtt
     4261 gctccctttg cctagctacg tgtaggtggt atacttataa ctgcgtatgc agtcttatgt
     4321 atcatggagg aagttgtatg tcgttaaaaa attatgtcta ttcacatcct gttaatgtgt
     4381 ttatcattgg tcgtttggga ttatctgtgg aagtgttctg tgagctttat ggttttaagc
     4441 aggggacttt gtcttcttgg gttaccaggg aaaaaacagt tgcttctttg ccgattgagt
     4501 ttcttcatgg gttgtcctta gcttctgggg agactatgga tcaggtatat gattgtttgt
     4561 gtgtgttaga gcaggagtat attgagtata aaatagctaa cgagttaaga a
//
LOCUS       DACGDM010000145         4500 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.153, whole genome shotgun sequence.
ACCESSION   DACGDM010000145 DACGDM010000000
VERSION     DACGDM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.153"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..761
                     /locus_tag="IXR05_002732"
     CDS             <1..761
                     /locus_tag="IXR05_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAQ4261173.1"
                     /translation="SSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSI
                     LLVLLVYFSFGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSE
                     ISAGRFTIWKAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNM
                     HNGFLQVLVSSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDE
                     MVEAHVLFNKRDVISIVFWYYLGSISYLYLKKEN"
     gene            763..1833
                     /locus_tag="IXR05_002733"
     CDS             763..1833
                     /locus_tag="IXR05_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261174.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            1820..3241
                     /locus_tag="IXR05_002734"
     CDS             1820..3241
                     /locus_tag="IXR05_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAQ4261175.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            3254..4261
                     /locus_tag="IXR05_002735"
     CDS             3254..4261
                     /locus_tag="IXR05_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4261176.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            4273..>4500
                     /locus_tag="IXR05_002736"
     CDS             4273..>4500
                     /locus_tag="IXR05_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAQ4261177.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLE"
BASE COUNT         1596 a          557 c          750 g         1597 t
ORIGIN      
        1 tttcttcgtc tagaggtgcc caggtagtaa tttgttcttt tttagtatta tttcttttgt
       61 tgtttgccaa ttcaaaattt agaaagagca ttagagaagt actacctgta aaaatcaaat
      121 ggatggtaag catattatta gttctattgg tatatttttc ttttggtact aattatgcta
      181 aggatttttt agcaacaatt cctgtatcga ttgatagaaa agtagaagtt atagagtcaa
      241 atgaatcaga taaaactcca cttccagaaa aagaagtaat attacagcat tctagtgata
      301 actccgaaat ttcagctggt cgttttacga tttggaaagc tgcgcttaaa gttataagac
      361 caactttgtt atttggttat ggagagaccg atttctatgg gaatagcgat gcaaaatttt
      421 tgaaaaaagt agatcttgat actacagatg tgaatgaact aaaaagagca catggaaaca
      481 tgcataatgg atttcttcaa gtacttgtat caagtggtat aattgctttt atatgtatct
      541 atgctttcta tgtgttaaat atctttagtt tactcaaaac attttttaga agtaaagtga
      601 attatgcgtt tcttggtatt gttttaattt ttatactatc tatttttata gatgaaatgg
      661 tggaggctca tgtacttttc aataagcgcg atgtcatttc aattgttttc tggtattatt
      721 tgggaagcat ttcttacttg tatttaaaaa aggagaatta atatgaagac agctttcatt
      781 gcttggactc ctttacattt gattaatata ttaaatgttt atcaaaattt ttaccgagaa
      841 tcaaaaggag atttatttat ttattctgaa tttgaaaacg ctagaagata tagtgagcgt
      901 ataaaagaat tagggctatt taatgatgtt gtttttgtga atcaccggaa aatcggttct
      961 tcctttaaac gtaaaattaa cttgttaact aaccataatc aatttttctc ggatgattta
     1021 tccgtttatg atgaaatttt tatacagggg gaaaattatt tcacaaaaat acttttctcc
     1081 aatgtttaca aaaaaaatcc agatgtaaaa ctaaattata tagaagatgg tttgggtact
     1141 tatttgaaga agagtatatt ttcaacaagt aaaaacgttc aaagagtttt taaaatatta
     1201 aataaaaata gcatcttcaa aaaaaaaatt gacgattatt ttgtctattg tccggaattg
     1261 ttactttatg atgtaaaaaa tataaaaaaa attcccaaaa tagatgaaaa cagtaaattg
     1321 atgaaaaaca tacaatcaat ctttgggata gaagaagttt ttgtcggaga taaatgtatc
     1381 ttttttgatc aacctttatt atctgatggt tatggcatag atgaaacaga tattttcgct
     1441 aaagtaaata gtatattttc tggaaaaaaa gaaactttaa ttaagcttca tcctagagca
     1501 aggacaaatc gttatggtga aaaaaacata ttgaattcca gtttaccgtt tgaagtcttg
     1561 ctacttgaaa atgacttctc ttcaacactt ttgattagtc ctatatctac aatttctttt
     1621 tcaccatcta tgatgtttga aaagacgatc aactctatta tgttggctaa attaatttta
     1681 aatgaatata cagcattatc tgaagataaa aaagaaacat tgacaaatat tgttcttttc
     1741 tgtgaacatt ataaccgtct atcagaagaa aaaattttac tcccagaaaa ctgggcagaa
     1801 ttaagaaagt tggtagagta tgggattatt taacacactt tccaagtcaa aattagttaa
     1861 gtccagtttc tggtatacta tagggaattt ttttattaag ggaatttcat tcataactat
     1921 tcctattttt gtaaatatta ctactcaagc agaatatggt ttgattaata atttcacttc
     1981 atttgtatca attttttcga ttcttgttgg gctaagccta aattcggcaa ttaataatgc
     2041 aagttttgac tataaagatg acataaatga atttatgtca tcggtacttt ctctagctac
     2101 actttcgtta attgtgttct tattaatagg gaacatatat tttttgtttt caaatgcttt
     2161 ttttgatatg aaccaacttg tatttaattt gatgttatta caaagttttg ctagttttgt
     2221 aattagttat atccagtctt attttacgat taactttaac cattttaaat atttgatttt
     2281 atcttttata tctacttttt tgaatattgc aatctctgta gctttgatgc agacattata
     2341 ttttgatgat aaatatgttg gcagagtagt cggcggaaca ctgtcatttg tgttgatagg
     2401 tttagtaatt tatttaagaa taatgataaa gggtgctcat ttttttgata aaaaacagtg
     2461 gagatacgct ttaaaaatct ctttgccgct aatcccacat tccttagcaa atatagtttt
     2521 agcacaattc gatagaatta tgattaattc ttatttaggt cctgctgcgg ggggaatata
     2581 ttcctacatt agtaacatag gtattattct aagcgtaata tggatgtcta ctaataacgc
     2641 ctgggttcca tggttctatg gtgagatgag taaaaataat gaaaaaaaag tgaagaaagt
     2701 tagtaactat tatttagtag tctttacttt gattacgatg attgtaatgg tagtttcgat
     2761 tgatttagca aaatttatgg ctccgaaaga ctattattct gggttatctt tagtggttcc
     2821 gataacctta ggctatttct ttcagttttt atatagttta ccagttaatg ctgaatttta
     2881 tgagaaaaaa acatcgttta ttgcgattgg tacagtagca agtgctatag ttaatatact
     2941 attaaacatg attttcatac ctaggttagg aataattgct gctggataca caaccgtatt
     3001 tacgtatttt ttacttttta tttttcatta taatatcgct aaaaaaatta cgaataaaca
     3061 attatttgac acaaaaaaaa tatgtatcat aataattttt gtatcaattt tttctttgat
     3121 acttcatatt ttaatcaatc aaatgttgat tcgttacgtt ttgacatcat tattgataat
     3181 tagtttagtt atatattttt taaagattaa gaatcgaatt atagatgact ataattcata
     3241 ggaggagata taagtgttta aaggaaaaac aatattagta actggcggaa ctggttccat
     3301 tggaagtgaa attgttcgtc agcttttaaa atatgaacca aaagctatca gaatttatag
     3361 tagaggtgaa gaaaaacaat tttatatgca acaagagctc tcaaatcaca ctaatttgag
     3421 atttttaatt ggtgatatca gagactctca aaggattgat tatgcatgtc gtgatgtgga
     3481 tattattttt catgctgccg caatgaaaca cgttccagca agtgaatata atcctatgga
     3541 agctgtaaaa acaaatgtga tgggaactca aaatgtaata gatgcagcga tcaaaaataa
     3601 tgtaaaacat tttgtaggta tcagtacaga taaagtagtg agtcctacta acaccatggg
     3661 tgcgacaaag ttattgagtg aaaaattaat aatagctgcc aatcagtata aaggaaaaac
     3721 agaaacaata ttttcttgtg taaggtttgg aaatgtcatg gggtcaagtg gatctgttat
     3781 tcctcttttt agtaaacaaa taaaaaacaa taaagatatt actttgacag atgttgatat
     3841 gacacgattt atgatgtcaa taccggatgc tgcaagatta gttctgtctg ctgctatgaa
     3901 ttcaaaattt ggagaaacat atgtcttaaa aatgccggca atcaatattt taactttagc
     3961 tcaatcatta ataaaaatat ataatgatac acatgatgaa aaatatagag gtgaaataaa
     4021 agttgtaggt atcaggccag gagaaaaatt atatgaagag ctaatgacta cagacgaaat
     4081 tgaacgctca tatgaaaatg ataaaatgta tatcattcca ccacactatc atgctactga
     4141 cgaactgtac aaagattatg aaaaaattaa aatcactgca tactcttcag atgcaacaga
     4201 attaatgagt ggacaggaat ttattagaat cgcaaaagag aataatgtcg tgacttggta
     4261 aggagtttta tgatgaaatc agaagtatat gtaattgcag aaattggtgt aaaccataat
     4321 ggaagtctag atttagcttt agaaagtatt gataaagcta aagaatgtgg agctaacgcg
     4381 gttaaatttc aaacatttaa aacgaataag ctagtttcca aaaaggctcc aatggcaaaa
     4441 tatcagaagg ataatcttaa agaggacagt tctcaatttg aaatgctaaa aaaattagaa
//
LOCUS       DACGDM010000146         4497 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.154, whole genome shotgun sequence.
ACCESSION   DACGDM010000146 DACGDM010000000
VERSION     DACGDM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.154"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            567..1478
                     /locus_tag="IXR05_002737"
     CDS             567..1478
                     /locus_tag="IXR05_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261178.1"
                     /translation="MKYLLHGYFIDYSTRNSSTLAILCLLHELRVVTRKQLYKLLNFD
                     RSISKQGVTNALVRLYEKQLIDRKKYGTEMYYYLTKEGHQSIGGYYTLPKVPEYNLNH
                     HLQINNYLIKGMALAKDHPHLKRIISERRTVYETKDLNPKTKGRKFFVPDFIFRFRDK
                     ENHEINWSFEIELTLKTRRRYREAIFPKYIRELRTRPESHLIYVTPSGAIQEELHAFK
                     RIFFKRETEKDASQQELFERLHIFSALEFEEGLKALLENDPAVNWRTVEREKIYPNGA
                     VQSRLNLFEESTENEEKPKVKFTPEVL"
     gene            1965..2231
                     /locus_tag="IXR05_002738"
     CDS             1965..2231
                     /locus_tag="IXR05_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261179.1"
                     /translation="MTTKNEQLKEQARKELQERGLIIEGSFEGDFETYIGCYARPINK
                     PTALDPMNEQEVKEQEKHAVNGFPQDFTEWYEWEINNGKLENFL"
     gene            2303..2644
                     /locus_tag="IXR05_002739"
     CDS             2303..2644
                     /locus_tag="IXR05_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261180.1"
                     /translation="MAKNTPYQVGDIFYSSWGYEQTNVTFWQIVKLTEKTAWFQPIQK
                     KTVEHYSSMSGKVVPMKDKFIEYPLAKTKDSIVKKRIDPETYPDMLCGYRSWDTFHRY
                     KNQAVYESSYY"
     gene            2699..3118
                     /gene="ssb"
                     /locus_tag="IXR05_002740"
     CDS             2699..3118
                     /gene="ssb"
                     /locus_tag="IXR05_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4261181.1"
                     /translation="MMNSVNLVGRLTKEVDLKYTPKGNATGTFILAVNRNYTNANGER
                     EADYIRCVIWRKAAETLAKYTGKGSLIGINGRLQTRSYQNQQGQTMYVTEVLVTDFYL
                     LESKEINEQRSKSMANNQNNSSIPGNEIQISDSYLPF"
     gene            3195..3491
                     /locus_tag="IXR05_002741"
     CDS             3195..3491
                     /locus_tag="IXR05_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261182.1"
                     /translation="MKIIDSYDQRTMQYLGSFDYTDENIINYVASLPPYQSVRLVDFA
                     SDELVLTTMGNFLDYVGDKKWLEKILSKLIAKQTGEEPINAIQLFNRYEQENND"
     gene            3506..3937
                     /locus_tag="IXR05_002742"
     CDS             3506..3937
                     /locus_tag="IXR05_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261183.1"
                     /translation="MKRLKRSIFIVLALIDFVGTGCEAIDVQKAPLSEIKQAITKQDE
                     EQPLNTQVEIVNQNKPSFSEEDFSLENGTRQFFSDLDRLNRVGVASALLHKSRMPTEE
                     RDRLYIKPTGWKQKKMKNGDYLYNRCHLIGYQRATSFPISM"
     gene            4119..4424
                     /locus_tag="IXR05_002743"
     CDS             4119..4424
                     /locus_tag="IXR05_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261184.1"
                     /translation="MKLDMPGRYKLLRVRLFLIKLTNLRMYGSITDLYSKDIRLRMQR
                     TLSKSKNVGHEIRDGRLAVYLSRVGKTCLIDSDESGNATKRFTEEIEQLAELNIRYF"
BASE COUNT         1652 a          709 c          962 g         1174 t
ORIGIN      
        1 tcaacgtgga aaaaccgcca cttatgagag aaaatggtca aaaacctaag cgggaagtct
       61 ccgaataaca taccaagcgc cgacagccaa cagataaaga atacactact aaaaatagta
      121 gtagcataaa atttaaaagg gaaaaaatca acccctaccc cagtcttggg gtctcaaaac
      181 taactccccc ctaaccccct ctttcagcct cttttgaaag agggggagaa tcaaccccac
      241 ggccaacgcc ccagtgttct tggggctgtc cagaacagaa acttgcgaga gagtgggggt
      301 aaaacaagtg tagaggaaac ttgaagactt gttcgaacag aaacttgcga gagagccgga
      361 gtaaaacaag tgtagaggaa acttgaagac ttgttcgaac agaaacttgc gagagagttg
      421 gagtaaaaca agtgtagagg aaacttgaag acttgttcga acacaaactt acaagagagg
      481 ggagtaaagc agttgcagag gaatcaggaa gatttgttcg aacagaaact tgcaagaaag
      541 cattattaaa ttgaaggtga tgaaatatga agtatttatt gcatggctat tttattgatt
      601 attctactcg caatagtagt actttagcga ttctatgttt gcttcatgaa ttgagagtgg
      661 ttactagaaa acagctatac aaactattga attttgacag atcaattagt aaacaaggag
      721 taacgaatgc tttagtgaga ttatatgaaa aacagttaat cgatcgaaaa aaatatggaa
      781 cagaaatgta ttattatttg acgaaagagg gacatcaaag cataggtggg tattatacgt
      841 tgccgaaagt tcctgaatat aatttgaatc accatttaca aattaacaat tatttgatta
      901 aaggaatggc attggcaaaa gaccacccac atttaaaacg gattatttca gaaagacgta
      961 ccgtctatga aacgaaggat ttaaatccta agacaaaagg aagaaaattt tttgtgccag
     1021 attttatttt tcgttttcga gacaaagaaa atcatgagat caattggtcc tttgaaattg
     1081 agctaacgtt gaaaacacgt cgtcgctacc gtgaagcgat ttttccgaaa tatattcgtg
     1141 agttgcgaac acgtcctgaa tcacatttaa tttatgtgac acctagtggc gcaattcaag
     1201 aagaacttca tgcgtttaag cgtatttttt tcaagcgcga aactgaaaaa gatgcgagtc
     1261 aacaagaatt gtttgagcgg ttgcatattt tttcagcttt agagtttgaa gagggattaa
     1321 aagcattatt agagaatgat ccagcagtca attggcggac agtagaacga gaaaaaattt
     1381 atccgaatgg cgctgttcaa agtcgtttga atttatttga agaatcaact gaaaatgagg
     1441 aaaaaccaaa agtgaagttt acgcctgaag tattgtaaaa gagggtgttc gcttcgctct
     1501 ttttttgtgc cagtttgctg gcaccgttca gacgcaagcg tctgaaccgg ctcgttttta
     1561 ggaaggacta acttgtttga tttatccgtt gtcaaagaag tggacgttcg agagtcccta
     1621 atcgtatagc agtcattcgg cgagtataac ctaaaacata acctgccaat tgccaagggt
     1681 aaaatgcacg ctgcgcgccc ttggcaatcg tcagaacatg ttttcgagcc ggttatgccg
     1741 aacgaccgct atacgaaaag ggcctctaaa cagaagtcca ctttgatcct tgacaactga
     1801 aacccaaaat caaacaagca ggccttcgtc taaaaacgag ccgaatgaag accttggggg
     1861 ttgcaccccc aaacccccgt gcccccgaca cactaccgaa aaggtggggg tgggtggcga
     1921 aaaaatcaaa taaaacattc tattcaagaa aggaagaaac aaccatgaca actaaaaacg
     1981 agcaactgaa agaacaggca agaaaagagt tgcaagaaag aggtttgatt attgagggga
     2041 gctttgaagg agattttgaa acctatattg gttgttatgc aagaccgata aacaaaccta
     2101 cagccttaga cccaatgaac gaacaagaag taaaagaaca agaaaaacat gcagtgaatg
     2161 gttttccgca agatttcact gaatggtatg agtgggaaat taacaacggg aagcttgaaa
     2221 acttcttata aaagtcagat gacgtgcaaa gagaatgatt ctctttgtac ggtaaaaata
     2281 taaagaaaga aggaaaaaga aaatggcaaa aaacacacct tatcaagtag gagacatttt
     2341 ttatagtagt tggggctacg aacaaacgaa cgtgactttt tggcaaattg tgaagttaac
     2401 agaaaaaaca gcatggtttc agcctattca aaagaaaacg gtcgagcatt attcgtccat
     2461 gagtggaaaa gttgttccaa tgaaagacaa gtttatagag tatcctttag caaaaactaa
     2521 agacagtatt gtaaaaaaac gaattgatcc agaaacctat cctgatatgt tatgtggtta
     2581 tcgtagttgg gacacgtttc atagatataa aaatcaagct gtttatgaaa gtagttatta
     2641 ttaaggggat agtttcccct ttcaaaaata ataaatagaa gaatggagag aaaaaatcat
     2701 gatgaattca gtgaatttag taggacggtt aacaaaagaa gtggatttaa aatacacacc
     2761 aaaaggcaat gcgacaggca catttatttt agctgttaat cgaaattata cgaatgcaaa
     2821 cggcgagcgt gaagcagatt atatccgctg tgtcatttgg cggaaagctg cggaaacttt
     2881 agcaaaatat actggaaaag gaagtttgat tggcattaat ggacgtcttc aaacgaggag
     2941 ctatcagaat cagcaaggac agaccatgta tgttacggaa gttctagtga cagatttcta
     3001 tttgttagag agtaaagaaa tcaatgagca acggtcaaaa tcaatggcga ataatcaaaa
     3061 taattcttca attccaggaa atgagattca aatttcagat agttatttgc ccttttaagt
     3121 gaaaaataat tttgttctat acctgatttc ttcaggtata gaacaaaaaa taaatagaga
     3181 tgaggcgatt ttttatgaaa atcattgaca gttacgatca acgaaccatg caatatttgg
     3241 gctcgtttga ttatacagat gaaaatatta ttaattatgt tgcaagttta cctccttatc
     3301 aaagcgttcg cttggtagat tttgcaagtg atgaattggt attaacaacg atgggcaact
     3361 ttttagatta tgtcggagac aaaaaatggt tggaaaaaat tttgtctaaa ttgattgcga
     3421 aacaaacagg agaagaaccc ataaatgcga ttcaattgtt caatcgatat gaacaagaaa
     3481 acaatgatta aagaggagag aaaaaatgaa aagattaaaa cgaagtattt ttattgtgct
     3541 agcattgatt gattttgttg ggacaggttg tgaagcaatt gacgttcaaa aagctccctt
     3601 atcggaaata aaacaagcaa taacaaaaca agatgaagaa caaccgctaa atacacaagt
     3661 agaaatagtg aatcaaaata aaccgagttt ttctgaagaa gatttttcgt tagaaaatgg
     3721 aaccaggcaa tttttttcag atttggatcg tttaaatcgg gtaggtgtag caagtgcact
     3781 tttgcataaa agcaggatgc caacagaaga acgagaccga ttatacatta agccaactgg
     3841 ctggaaacaa aagaaaatga agaatggcga ttatctttat aatcgttgtc atttgattgg
     3901 ctatcaacgt gcgacaagtt tccccataag tatgtaatac gaaacgggag gattaatctt
     3961 aagattaatc acaactaacc tatttgacag ttggaatgaa agctatcatg tctgctgaat
     4021 caactggtct gatactccta catgcaataa agtctactag gaagttattg tatgaagcta
     4081 ggtaaaggcg gcagaacaat ttctaagtgt ggaatcatat gaagttggat atgccgggac
     4141 gctataaatt actcagggtg agactgtttt taattaaact gacgaacttg cgaatgtacg
     4201 ggtctataac cgacttatat tcgaaagata taagattgcg aatgcaaaga acattatcga
     4261 aaagtaagaa tgttggtcat gaaattcgag atggaagact agcggtgtat ctgtcaagag
     4321 ttggtaaaac atgtttgatt gattcagatg agagtgggaa tgcgacaaaa cgttttacag
     4381 aagaaataga gcaactagca gaactgaata tacgatattt ttaaatactt tagcggagaa
     4441 taaaaaaatc ctctacagaa aactacggag ggcaacatgt gctattgttt caacaat
//
LOCUS       DACGDM010000147         4425 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.155, whole genome shotgun sequence.
ACCESSION   DACGDM010000147 DACGDM010000000
VERSION     DACGDM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.155"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            690..1658
                     /locus_tag="IXR05_002744"
     CDS             690..1658
                     /locus_tag="IXR05_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4261185.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="IXR05_002745"
     CDS             1669..2484
                     /locus_tag="IXR05_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAQ4261186.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="IXR05_002746"
     CDS             2552..3262
                     /locus_tag="IXR05_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4261187.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="IXR05_002747"
     CDS             3298..>4425
                     /locus_tag="IXR05_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAQ4261188.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1490 a          661 c          921 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DACGDM010000148         4422 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.156, whole genome shotgun sequence.
ACCESSION   DACGDM010000148 DACGDM010000000
VERSION     DACGDM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.156"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            270..1001
                     /locus_tag="IXR05_002748"
     CDS             270..1001
                     /locus_tag="IXR05_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4261189.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            1146..3173
                     /locus_tag="IXR05_002749"
     CDS             1146..3173
                     /locus_tag="IXR05_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAQ4261190.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            3281..4378
                     /locus_tag="IXR05_002750"
     CDS             3281..4378
                     /locus_tag="IXR05_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4261191.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         1550 a          715 c          920 g         1237 t
ORIGIN      
        1 taggcagtca agtcacattt tgatagatag gagggggact tacgaattat tttaaaggct
       61 atgacagctg tatttctaga ttgtgtttgc atcaagttgc aataaaaact agaaatcaaa
      121 tcgggctgat aatcatttat aactaatcga tacataggac caaatatagg tctatgttct
      181 tttatttcat aagtatcgta aaacagaatt ttgctatgga ttaatccaat cgactgatat
      241 gtttagtaaa taaagaaaga ggaatgtcaa tgatgaaaaa agaaatcgta ttaacagcag
      301 caatgatgtt attcagcatg gtagcaagta cgacttttgt ttctgcaact gaagtatacc
      361 caaaggaata taacacagaa ggaacgatta catttgaagc aggagatgag ggtgtaactc
      421 ctcctgttga tccagagaat cctgatccca ataaacctgt cgatccatca gatcctccaa
      481 gccctggaac aggaggggca ttatcgattg attatggatc aaaattcaaa tttgggactc
      541 aaaaaatttc tactgcggat aaaacgtatt atgcagctgc tgatgtgatg aacgatgggt
      601 ctagaaaacc gacatatgtc caagtgacag ataggagaag taccttatct gggtggaaat
      661 taagtgtctc tcaaccagaa cagtttaaaa ctgccagtgg ggatgaacta gttggagcac
      721 agctgaaatt tacgaaaggg caggctgttt ctttggttga tccaacatat acgccgcaaa
      781 cggtgaattc tgaattaacg ttgacaccgg gaggaaacaa tacgttagca attaatgcta
      841 aatcaggaac aggtgtgggg acttgggtct atcgatttgg tgcaaatgaa aatgaaaatc
      901 aagatgcggt acagctttcg gtacccggta aatctgtcaa gttagcgcaa caatattcca
      961 ctaaattagt ttggacatta gaagatacac ctaacaacta gtttactgaa aagaactgtt
     1021 aaaaataaat acgtagtcat attgtcttgc gaggtaatcg agcaaaaatt gtcaaaggct
     1081 aggctaaatt tgtttggata cgaatagttc atctaggaat ttaacgatca ggaggaaaag
     1141 atatattgaa aaagaggagg atcgtgctca ttttaagcag tctcttagtg actaatatct
     1201 ttccgatcat agggtactct ttggaattga atcagttgga gcatggaaat agaagagacg
     1261 aagaaagcaa actcacttcg acattcgaca gtttaataga atccaaccag acacaagaaa
     1321 gcagtgagga tttaagtatt tcgagtagtg gagagaccac tgacaacgta gaagctgagg
     1381 gttcggacaa acaaggacta gaagatgcac caatttctgc ggttgagctg cctgacgatc
     1441 ccaatattat ttctatcgat aaaatttttc aaacacctat cggtactagc acgtccatat
     1501 tggaaaatgg gaagttactg cagttgaacc cagcagaaag gtctcaaaga ggagctattt
     1561 ggtcaaataa gaagattagt ttactctcgg attttacatt taaatcttat ttatacttag
     1621 gaaatcaacg agatagagcg ggagatggca tgacctttac attgactggc gatcctagaa
     1681 tggctagtaa tcccagtcaa gttattggat cgccaggtat gggaattggc tcatattcta
     1741 ctcgttctgg ccaaccttac attgcgaatg cgctctcgat tgagtttgat acgtataaaa
     1801 atagtggttc ttctgatcga atggatcgag agataactgc tgataataga gggcatggac
     1861 atgtcgcttt tgtcacgcct aaaccaaata ataataatta ttctggagag catactggcg
     1921 tgacggtagc tcctacattt ctttctaatg gcacatggcg cttgttaata attaaatggg
     1981 acgcggagca aagaagtctt acttatgatt tggaaggtgt cggtcactct tctcggatta
     2041 tacctgatct cattaggcag tttggttcta cagaagtaaa ttgggggttt acttcttcaa
     2101 caggtacttt ttttcaagaa aatgctgtcg ctgtcacgcg acttccatcg aatgtcacat
     2161 caacagctga tgtaaaagtc aacgatagtg attatggggc catcgctgaa gctggaggaa
     2221 acgataagat aactatcaga aatacattga aggtcgaggg ggattttctt gaatataaga
     2281 aaatgcagac tagtatcgac ctcccacaag aattaactat tcccgagcat atcttgatca
     2341 atggaaatca aattgatgcc aaagatatct tgataaccgg aaatcgagtc acgctaaatc
     2401 tgacagatta ttttattgct ggagatacgt taataatcga attggagaca actttgcagg
     2461 aagtaattcc tgaaaaagta ctcactatgc attttgaata ccttgaaaac gggaatttga
     2521 ttgagcaatc gaatgaaata aacctaaaga tcgcaaagct gaaggagata gatatccatg
     2581 tttattataa agataaagac agtcagattg atattgctga aatgaaaaca atcactggga
     2641 aaataggaga gaagtataaa gaaactccta ttgatattga agggtatgtt tttgactcgg
     2701 attcagcgaa tacagaaggc atcttctccg aaaatacaga ggatatctat ttttattaca
     2761 gaaaaggcaa actttatctc tcaactgctc ctcaatatgt caattttgga aaacataaaa
     2821 tatccagtag accattaagt gaattcggac agttttcagg tgggttgaaa attatagatg
     2881 aacgggcttt tggaagttgg aaattacaat tgaaacaaga gaaagttctt acaaatggag
     2941 attttgagct tccagaagct ctttcctttg ttacctctga aaatacaacg gttataggga
     3001 catccgctgt tacgattttc gaaagtgatc aaaagggtga aagcgatttg tcctctcttt
     3061 tagattctac agctcatcgt ggaatcagaa tagatattcc tgtagaaaac caaagaatcg
     3121 gaacctttga ggggaaacta tcttggatac ttgcagatgt cccaggaaat taacaggaag
     3181 agaagaatat aacaaaatta ttgagtttca agaagggcac aggtaccata ggctcttgtg
     3241 tcccacagag acaagatttt gttatagtct tctcttacat atgattaaag gagcgatttt
     3301 cttgagacca aaacaacaat tatttataac actcctagtt attttagggg cactttttaa
     3361 caatatatca gtgtcagcta gtgcatttaa tttttcagtg acgccgataa cttcagagaa
     3421 tcaaatcgac aagagaaaaa cttacttcga tcttcaactt gatccggatc aggaagtaga
     3481 agtaaaagcg gaattgagaa atgatacaga aaaagaagtg aaaatcgata tttctgtgaa
     3541 tagcgcaacc accaattcaa atgtgatggt tgaatacgga aaaaacgaga ttgaaaaaga
     3601 catgagcctg atctttgatc tggtagatta tgtgagctat ccacagatag tgacgctaaa
     3661 acctaaaagt gtccaaaccg ttgcttttca tgtcaggatg ccgaatgagc gatttgatgg
     3721 tgtattggct ggtgggatca cattccaaga aatccagacg gaaaaggacc aaacagaaac
     3781 taaggatcaa agcttatcga ttgagaatga atacacctat attattgctt tgttgatgca
     3841 acagacactg aacgaagttg ctccgaacct tactcttcat gaagttaaac cagatcaaat
     3901 caatgcaaga aatgtcatct tagcaaacgt tcaaaatgat caaaaaacct atatcaatca
     3961 agtagttatt gaaacaaaaa ttacaaaaaa aggacattct gaagttttat atcaagagga
     4021 aaaagaagga ttgcagattg cgccgaatac aaatttttct tttccaactg ctttaaatgg
     4081 tcaaccgcta accccaggtg aatatcacct tacaatgact gttttaggaa atgaaaatga
     4141 aaatggaaaa ttttcgagaa aaaaaggaaa tactacgatc aactatacca atcaatgggt
     4201 atttgaaaaa gattttacaa tagacggaaa agtagccaag gaattgaaca cgacggatgt
     4261 tacgattaaa aaagacaata attggattta tatcttagta gcttcacttt tcttattgtt
     4321 tattttatta tgcatacttt tgtttgtttt gagaaaaaaa gaagagaaag aaaagtaagg
     4381 ttaagataac aaatagtaaa tttttattat tgtaggatgg tt
//
LOCUS       DACGDM010000149         4350 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.157, whole genome shotgun sequence.
ACCESSION   DACGDM010000149 DACGDM010000000
VERSION     DACGDM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.157"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(51..947)
                     /locus_tag="IXR05_002751"
     CDS             complement(51..947)
                     /locus_tag="IXR05_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4261192.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(940..1620)
                     /locus_tag="IXR05_002752"
     CDS             complement(940..1620)
                     /locus_tag="IXR05_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4261193.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(1621..2403)
                     /locus_tag="IXR05_002753"
     CDS             complement(1621..2403)
                     /locus_tag="IXR05_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4261194.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(2396..3313)
                     /locus_tag="IXR05_002754"
     CDS             complement(2396..3313)
                     /locus_tag="IXR05_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4261195.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(3477..3800)
                     /locus_tag="IXR05_002755"
     CDS             complement(3477..3800)
                     /locus_tag="IXR05_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4261196.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
BASE COUNT         1278 a          948 c          758 g         1366 t
ORIGIN      
        1 tatatataag ataatacatt tttctactag ttctcactaa tcttgtataa ttaaaccctc
       61 cgcaacttga cggagatgga gaagatgccc ccgtctaatc tagcggtcat ctctcctccc
      121 attccttcca ccaatttttt tgacaggtaa agcccgattc cgctagattc cgtatttgtg
      181 cggctggtat tttcggtata aaaacgctgg aagacttttt caacagaggt ttgcgttcct
      241 ggtttgatag gattggccac tgttaatcga atgaatggat cctcttttga aaatgtcacc
      301 tttgcttgtc catctgcata acgcaataaa ttctgtatga tattttgcag cactcgcagc
      361 aacatgagcg gatctgctaa tacagttgta tttatcgagt gttcagcgaa cgctacctcg
      421 atatttttct cagaaaattg ttcataaaaa gagaaaaata cttcttccac ctctttagaa
      481 aaagaaagcg tatggagatc catttctttt tgcttcgtct ctattcgagc aagatcataa
      541 aactgatccg tcatactgag taatcttgca acagattgtt tgatgatcgt taaatacttc
      601 tcccgtttct ccgtatcctc tacctgttcc agtaattgta cataaccgtt aatagcagtc
      661 aaaggagttc tgagatcatg agaaaggccg acgatcgata gtctgatgtt ttcttccatt
      721 tcttgaaatg cttgtccttt ttgttcattt tcatccaacc atgtattcag tgcatctact
      781 aggtccatta gattcttttc tcgaaattcg actgaaagac gaccaccata ttcttgtcgt
      841 tcagaaagag tggcgatttt cttagttaat ctcttgattt ccctttgcag gaagaaaata
      901 aaacttccca taaagataac aacgagaagc aacagccatt taatcaaatc taaaccccac
      961 tccccacacc gtatgaatat acacagcatg tgcctttgct agcttccctc gaagattgga
     1021 aatatgcata ttcactgttt tctcactatc aaaatatggt tcttgccaaa ctgtttcata
     1081 aagatttgct cgcgaaaata cttttttcgg atgttctaaa aaaagcttca gcagatcgaa
     1141 ttctcttcct gtcaaatgga cagccacacc attcacattt acatccctcg actctttgtc
     1201 cagtaagatt tccttgtaat agatgcgttg cgacagatct tttacttgga cagaagtctg
     1261 atgacgaagt tggatgccga ttcgtaacaa aagttcttcg atatcaaatg gtttcgtcac
     1321 atagtcatcc gctcctgctg ccaacaagga aactttatct ctttgatcgc tttttgctga
     1381 aagaacgatg atcggaacat tcgatgtctg tcggatttct gctaacaatg cttcacctga
     1441 aagccctgga agcatgagat ctagaaggat caaatcgaca ggatatgtgc ttaacaataa
     1501 ttttccttcc gtacctgaat aagcatcaag aagtttgtat ctctgttcaa gaacctcctc
     1561 cagtaaggaa tgaacagctt catcgtcttc gataatcaaa atagtttcca gcaggaccac
     1621 ctacttaatg tcagattttt ggaaaataaa cattcctaga gctgatgata ccacgattgt
     1681 tactagactg accagaatca ttttcggtgc ttgcgaataa gttgcttgtt gcgcaaagtc
     1741 cgtatacatg agccacgttt ccgtaaacca ctccgttaga aattccaagc ctttgatttt
     1801 tgcgaaaaca ccgggaatga aggccgttcc catgatataa agaaaagaaa gaagcaaact
     1861 gacactggta cttctagtga tgaatgtcaa agccactgga acagataatg tccctaatgt
     1921 cagcagaagc aatacaggaa atacttttag aacataattt ccatagtttt tgattccctc
     1981 aacttcacca aatccgaaag caagtgtgta agcaagcatg gctagtcccg tgatcaaaac
     2041 cacgccaagt gttgtgatca aaagcgtaac gagaagtttc gacacataat aagtcattcg
     2101 attccgtcct aaagataacg tattgcgaat cgtaccgttt tgaaattctt ccccaatata
     2161 aaagcacgca aatgctgcga aagccagaag aatccatgca gccatttttt ctaccattaa
     2221 aatccctgtt gcaccgttga tgactgtatc cgttgcttgg tttaattcat tgccgtattt
     2281 tgtatgcata taccattcgt tccaagaata aaaaagcgga agtacgacca tcagtcctag
     2341 tgagacccac attttacggc tcttccatac ttttattttt tcagcagtta atagattaaa
     2401 catgtggatt gcctccagtt aattgtaaga aataatcttc cagtttttgc ccaactaggt
     2461 gaataccatc cacaggaact tttgcttcta ccaatgcttg attgatggct gctacttggt
     2521 caattccttc aaaaagctgg ataacacggc tagattgtac aaaataatcc ctataaccaa
     2581 gagagtcgag aaccgttact gcttgttccg tcgccgaagt gtcaattttt ataaattgac
     2641 gagattcttg tgccaattct tctttcgata attctttgat caagtgtcct tcatgcaaaa
     2701 taccatagtg agtggcgatc tgtgacaatt catctagcaa gtggctagaa agcaagacgg
     2761 tgatgccccg ttcttttacc aaacgttgga tgatttctcg catttctgcc atccctgctg
     2821 gatccatccc attcgtcggt tcatccaaaa tcaaaaattc tggattcgtg atcagtgcat
     2881 ttgcaatagc taaacgctgg cgcataccta aagagaaatt ctttgctttc tttttccctg
     2941 tattttccaa tcgcatcatt ttcagcaggt cttcgatttc tctatccgac acaccgccgt
     3001 tcgctgcttg gatacgtagg ttatctcttg cagttaattc tggataaaga gcaggggttt
     3061 caatcgattg acccatacgt cgtcttgctg cctgcaaatc cgtcgttcca aataattcga
     3121 tcgaaccttc atcaatcgag atcaaaccca taatagttct cataaaggta gacttacccg
     3181 ctccattttc cccaatcaat ccatagatca ttccacgttt gatttcgatt gatactttat
     3241 ctaatgcttt ggcagcaccg tattttttgg ttataccagt tgctttcaag accgtttcat
     3301 ttccaaaatc catacttatc cttctttctt attgatgagt gaagtatagt tgacgggtat
     3361 aaagaaagca gccagaaatg tataaagaaa gtgtaaattt tccaattgaa tgtcaaaaaa
     3421 aacaatcgga caatacgtgt ctttcctatt atcaggcagt ttgttatacg cttgtatcag
     3481 tttcctgatt ctttcttttc gaccaaagtc gtttctctgt attcctcttc actgaaaatt
     3541 tttgcttctt tcagatcaag cttgagtaat tttaccagac cggttataag gataactata
     3601 gcaagactcc ctcccagaaa aattagactg tctcgcagac gtggttgcgt tgtcttccaa
     3661 tcaaagagcg caccaaacag tgctaatcca agtggactgg ccaccatggt aatcgttgtt
     3721 atcgttgaca taagtcgtcc ttgtatatgc gttggaactt ctcgctgaag ccagaccata
     3781 taaaaagcaa aagaaaacat taatccttaa aaacggactt atgaaaaata atacatgccg
     3841 tttgggattt acaattagct accaaataag aggttatgac aaaagacttt tcacaatccc
     3901 ttcttccgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatttatc
     3961 aaacatgaga agcaattttt gtaaattcct tcttatttct tgaagctgac cacttctgtc
     4021 acaacctcag aagcggataa ataatattgt ttgatgatac tttatctttt tcccgtttgt
     4081 ttatagatcg aatgatatta tagaccaaga atcctaccta ttaacatagc taaaaacaca
     4141 aaaaaggcac tttccaaatt gtggaaagtg ccagaaaagt taggattaag gtaactgcgc
     4201 tcagcattgc ttcgcccagt acgattctcg taactcgtga actcgaacga taatcgcaat
     4261 taacgttttg agaactgtga agctttacgg gctttcttaa gacctggttt tttcttcgta
     4321 tcattgaata agtttgaaaa accttgattt
//
LOCUS       DACGDM010000150         4312 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.158, whole genome shotgun sequence.
ACCESSION   DACGDM010000150 DACGDM010000000
VERSION     DACGDM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.158"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..281)
                     /locus_tag="IXR05_002756"
     CDS             complement(<1..281)
                     /locus_tag="IXR05_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4261197.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLKYQSLTLPLKMQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMRLNEGNGYLRSVSNNGWQLLDQHEEN"
     gene            complement(730..1272)
                     /locus_tag="IXR05_002757"
     CDS             complement(730..1272)
                     /locus_tag="IXR05_002757"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261198.1"
                     /translation="MKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGN
                     DFVDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADL
                     QVENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTL
                     FYRQNVSQRKLERSEDEIEW"
     gene            complement(2049..2239)
                     /locus_tag="IXR05_002758"
                     /pseudo
     CDS             complement(2049..2239)
                     /locus_tag="IXR05_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349771.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2359..2721)
                     /locus_tag="IXR05_002759"
     CDS             complement(2359..2721)
                     /locus_tag="IXR05_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261199.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(2725..3033)
                     /locus_tag="IXR05_002760"
     CDS             complement(2725..3033)
                     /locus_tag="IXR05_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261200.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERIMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            complement(3042..3461)
                     /locus_tag="IXR05_002761"
     CDS             complement(3042..3461)
                     /locus_tag="IXR05_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261201.1"
                     /translation="MTDLSEKMTIKNLADELGVSKNTVRNQLVNSGFDLAQYKENGII
                     MLDKELIGVVRSIYRSKSDQLTGQLPVNNTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(3454..3687)
                     /locus_tag="IXR05_002762"
     CDS             complement(3454..3687)
                     /locus_tag="IXR05_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261202.1"
                     /translation="MTEKQKYFGKKNWLVNLTGDYVVVVFLDSKKMSGKLLDVTQYEL
                     ILKNNKIDSPIIIPKHAVKYIYAVAESSGEAND"
     gene            complement(3684..>4312)
                     /locus_tag="IXR05_002763"
     CDS             complement(3684..>4312)
                     /locus_tag="IXR05_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAQ4261203.1"
                     /translation="SQFLASSMKNFIHDLFIEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPPEITTWWRLELQ
                     LRRGKATDWHEMVHESLDSFASPHYFPPNTKVTERIMVKGLLYDHSEWGNLAKNTKKK
                     YRDLLKQESQNDELTNHLRETFAESADDLKKELDTWLLGLDVTEEEEK"
BASE COUNT         1221 a          959 c          618 g         1514 t
ORIGIN      
        1 atattctctt catgttggtc taacaactgc caaccattat tactaacaga tcttaaataa
       61 ccattacctt catttaggcg cataagctgt tcaaaattta aaatcaacac atcatttgga
      121 gtgtgataat aaatattttc tttcagtttt ccgactatgg taattcggtc aattgaccac
      181 tgcattttta agggaagggt caaactttga tactttaacc gcctgttaga gggggctgtt
      241 aatttttccc actcatttat gatcgtgcct tttttactca aattttgttc ctcctcaaag
      301 aaaaagagac ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc
      361 aaaaaatctc tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg
      421 agctagtgcg attagtttcc gtaaaggtcg agaacgtgtc cagcgttgct cgactttatt
      481 tttttgctct tttttcagtt tatttatttg ataactcaat aatagcactt ctctttagct
      541 atgcaaatat ccaaaaaata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta
      601 acgctaggtt ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt
      661 agtggtttag ccgtcaactc cttatcctcg gcacaaaccg cctccggtac cgttgactgc
      721 acatcgtaac taccactcga tctcatcttc agaacgctct aatttacgct gtgagacgtt
      781 ttgacgataa aataaggttt tctcctgctc taacacttct aattcctcag aaagccccat
      841 atccttttct gcaagaccaa aacggataga caaacgagtg atcgattttt gaaatgcgtt
      901 ttttaatcgc tctaaacgct ggcgtaaaga gcgattttct tctttcagct ttttattttc
      961 cacttgtaaa tctgctaatt gttttctacc agacaaatga cgctcttctt ccaatgtagc
     1021 tacatactca tttaattctg tattttgctc aagcatctgt aaatattgct cactcatgtt
     1081 atcagcattt ctcttggcat ttgttgctct cgtagctcgt tgatacaaat caacaaaatc
     1141 attcccagat aaatgatacg aaccatcagg aagcctcttg aaactttcta aaggaacaat
     1201 atctttttgg aaaatgaccg ccatctcttt ttttacattc agcatatttt tcttctcttc
     1261 ttcaatcttc actctctcag aagccaccag agccttttct cgctcatttt cttctctttg
     1321 cctagaaaaa tatacctcaa ctcatcagaa acgctctcac gctcttttac ggccgtttga
     1381 cgcaattctg aaatctcgct catgatttct ttatattcgt gaacatcttt gattttgtta
     1441 gtaccgacta actcacgctc ccaaccaaaa tctgccatca aacgttcaat tgactcaact
     1501 tcctgattcc taaaattatt ccaaatcact cgaccattct ctttatctgc tcgtaaaccc
     1561 tgctgttgca aggctttgtt aaaacttggt tgcttttgaa caccccgttt atacccttca
     1621 gcaacaggaa caatattcaa atgcaggtgc ggacttactt cgtcattatg aataacagca
     1681 ttgtagacgg ataaattagg attccgttct ttaaattctt tgaaatattc aactaaaatt
     1741 ttgttggcaa tcactcgatt ttgttctgct tgttgttccg atatgccagt agaagaacca
     1801 tcatcacgag tagtacgaaa atcatcaaga gtaccaattt gcacgataaa ttctcgctgt
     1861 ggttccaatt ttttatcctt gcgaaccttt gctaaatagt cctcgatttt tctatcggct
     1921 cttttctgct ttgcattata tttttctacg gcttcaccga ataattcttc atatttttca
     1981 cgaatatttg tttgttctaa atagatattt tcatccgatt ttgtgaaatc aatatgctta
     2041 tgccagtcat tgattttttg gctatcagtt aactcacgat tattatgaga aatgcttgta
     2101 ttctttgttc cctttttgaa cgaaatactg aaccccaagt taaaaccctc cttcggctgt
     2161 cgctaataaa aagagtgtaa acctttctgt tactctttgt caaagagtaa cattttccta
     2221 attgtgacat ggctgtcaca attccaaatg ctctccgagg gtattcgctg tcacaagtga
     2281 caacgaaaaa aggagccgaa agcgtgtcac gctctcaact ccttttacgc tttattttgc
     2341 ttcacgcaaa ataatcgctt atcgtaaatt cacgtcatta aatattgacg taaatttact
     2401 ctcactcatc tgacttttct tattcggtat cactccgaat aagccgtcag attcatcggg
     2461 ataatctcgt tcgcttggcg ctgatttttc atcagcaagc cactcattat ccactgattt
     2521 ttcgtgttgc tgatcgtcag aaatcgacga tagccaccgc tcaaaatcag caaaagtttc
     2581 aaacccaaaa cgcttccgaa gagccttgcc cattgcagca ttttctttct caatcaagcg
     2641 ttttttctgt tggcgaagtt tcgcttgttc tttttttaat ttttcttctt gcgctttaat
     2701 atctgctaaa gtcattccca taaactacat ctccttttct ttggaattaa taacggaaat
     2761 ttggtttaac tgcataacat gactcattaa tttcaaccaa aattcttttt ctgattcatc
     2821 agttgtttgc gctaaatgct tatgaacaaa ttcattagtc aaaactgaag attttgctaa
     2881 atcagcattg ataaccgagt tgagaacatc cataattcgt tcaagcattt cactataatt
     2941 atcttcatcc ggcaaattca aataatcagc taaccgttca tacatcaatt caattctatc
     3001 gactgtttct tctctcaaat caattttatc catgtcacac ctcacttcca gaattgccac
     3061 cattttcgat tttttaattc ttgattttct agtaacaact gatcgttttt ttgttgctga
     3121 agcagggtca atttttgttg atcacgaatc atttctgtta attcagaaat atgtttgtcc
     3181 ttctcagcta attgatcacg caaaaactca ttctcttttt ctaaaggaaa atcactgcct
     3241 gtgttattga ccggtaattg accagtcaat tgatcacttt ttgaccgata aattgaccga
     3301 acaacaccaa tcaactcttt atctagcatg ataatgccat tttctttata ctgagcaagg
     3361 tcaaaccctg aattgaccag ttgattgcgc actgtatttt tcgatacacc caattcgtca
     3421 gcaagatttt ttatggtcat cttttctgac aaatcagtca ttagcttctc cactactttc
     3481 agctaccgca taaatatatt taacggcgtg cttagggata ataatcggag agtcaatttt
     3541 attatttttc aaaatcaatt catattgcgt tacatcaagt aacttaccgg acattttttt
     3601 gctatccaaa aaaacaacca caacgtaatc acctgttaaa tttaccaacc aatttttctt
     3661 accaaaatac ttttgttttt ctgtcatttt tcttcctcct ctgttacgtc tagccctaga
     3721 agccatgtgt ctaattcttt ttttaaatcg tctgccgatt ccgcaaaggt ttctcgcaaa
     3781 tgattcgtca attcatcatt ttgactttct tgcttcaaca aatccctgta ttttttcttt
     3841 gtattcttag ctagatttcc ccactcagaa tgatcataaa gcaaaccttt caccataatc
     3901 cgttcagtaa ctttagtatt tggcggaaaa taatgtggac tagcaaagct atccaaactt
     3961 tcatgaacca tctcatgcca atcagttgct tttccccttc gtaactgcaa ttctagtcgc
     4021 caccatgtcg ttatttccgg cggaacaatt ttacgttttc tttcttgttc cagtttttta
     4081 ttatacatcc gaatttgtcg ttcactggca cgactacccc aatatgccgt ttctaactta
     4141 ccagaacgcc cataaattgg tttaaaagac acaggatcaa ctacccgata ttgtgtaata
     4201 aactcatcag gtacatcgat aatgtcgcaa gcaatatccg cacgtgaaaa gtgaggttcg
     4261 ataaacaaat catgaataaa atttttcatg gaactagcta agaattgact aa
//
LOCUS       DACGDM010000151         4246 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.159, whole genome shotgun sequence.
ACCESSION   DACGDM010000151 DACGDM010000000
VERSION     DACGDM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.159"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            61..1362
                     /locus_tag="IXR05_002764"
     CDS             61..1362
                     /locus_tag="IXR05_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4261204.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1389..1649
                     /locus_tag="IXR05_002765"
     CDS             1389..1649
                     /locus_tag="IXR05_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4261205.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2648..3883)
                     /locus_tag="IXR05_002766"
     CDS             complement(2648..3883)
                     /locus_tag="IXR05_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAQ4261206.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1228 a          682 c          879 g         1457 t
ORIGIN      
        1 acattctttg cgttgtcatg caatgaatgg ttcatatttt attgaaaagg agtggtttta
       61 gtggaaaagc tgatgaaatg ggtcgaagag aaacttgtcc caccaatggc aaaaattggt
      121 acacagcgtc atttattagc aattcgtaat ggggttgttt caacattgtc attgattttg
      181 attgggacat tttttatggt ctttatcaat ttaccgtttc ctggatggaa tgaatttatt
      241 gccccttatt cggcaacgat tgttttaccc tttaggatga cgatgggatt gatggctatt
      301 tatgcaactt ttgttatggg ttcggatcta gctaaatcat atggattaga tagtgtgaca
      361 ggtggtatat tatctttagg aacgttcttt atgttacaag ttcctgtaaa cgttttaact
      421 cctgaagagg cacctcttgg ctgggtctta cctatgagtt ctttgggagc atctgggatg
      481 tttgcgggga tcttatctat gatttttgca gtggaagtat atcgtttctt taaaaatcga
      541 aatattacta tcaaaatgcc agaacaagtg ccacctgctg ttgcccgtag ttttgaggca
      601 ttgattccag gtgcagtcat tttaacaatt acttggctga ttcgaagcgt cgcgggcttt
      661 gatgtaaacg ctgccttatt atcgttattc gagcctttaa ccaatatttt agggaataat
      721 ttgcttggtg ttttactacc aatgtttttg atccatttgt tgtggtcatt tggtatccat
      781 ggcatgagta ttgtaggggc tgttgttcgt ccaatgtggc tgatcatgtt ggatgagaat
      841 gcaaaggcat tggcagatgg tacagctgcc acccaattac cctatatcgc tcctgaacag
      901 ttttatcaat ggacggtaac aattggtggt gcaggagcaa cgatcgtggt atctgttttg
      961 tttatattct tctgtaaatc aaaattcttg aaagaggttg gtcgtttttc tattattcct
     1021 ggtatcttca atatcaatga gcccataatt tttggagctc ctatgatgtt gaatccttac
     1081 atgttcatcc cgttcaactt agttccttta gttttgacta ttatcagtta ttttgcagtc
     1141 aaattagaaa tggtcaatag atttactgtt ttgccaacat ggacattacc agctccaatc
     1201 ggcggttatc tttcagcagg aaatgactgg cgtgttgtta tcttgatcat gatcaacaca
     1261 ttgatagcat ttattatcta ttatccattt gtaaaagctt atgataaaaa gatgctgtca
     1321 gatgaacaaa gtcgtggaga aaacgaagtc cagactgtct aagtttggtt tttagaaggt
     1381 gggaaacaat gtattggctg attttatttt ttgtttttat ctttttatta acggctagtc
     1441 accttatatt gaatatgcta gctacatatc atattcaaat caatcgatgg atttgggcac
     1501 tggcatcatt tttgatcgtg attcttccaa agatcattgt accgcatatg aatgttttgt
     1561 tttcatgggg gacatatgta ctttgtggaa tttttgctat caattttatg atcgagcagc
     1621 atagatggtt tgtcacatcg aagctttaaa tgttctaaaa gtggttgtaa cagaagtggt
     1681 tagcttcaag aaataagaag aaatttacga aaattgcttc ttaaattttt gtgaaatgtt
     1741 ggcttatttt tcgtttggtt gaacttatta ccgcagatgc aagcttttga ccaccgttta
     1801 ttcggaatat gggactgtga caaggctttt gtcacagccc ttttttacat aaagattatt
     1861 attgttttaa ctgttttggc agaaagaagg aggaaaaaat ggaaatttta tcagcaatgg
     1921 atttagaatt agtagatcta ctaccaaagt gatcaagtca aatatagatt tgggagctta
     1981 caaccatata gtaggggctg cagtatggtg tatgaatggt aatatgtatg atgtgagtgt
     2041 ttattcaaat catgaaacgt gtatagaaat aattgtgctg ggaatagcaa tcagtcatgg
     2101 tgaacgtgac ttttagtgta tcgttgctga cgacatagaa cattctgaca tgatctactc
     2161 aatatgtggg gattgctggc agtttatata ggagtatgca tcggattgcg agatcattgt
     2221 ctcaacagaa gagggaggtt gattatcaaa gataaagtgg taaatcctac atttgattta
     2281 gtaattgttg aggggactag cggcacaaat ctctacaaag cgatgcttct agatctatat
     2341 gacacatttt aagaaaatgt atttgcctaa ttattatggt ctttcttttg aagaaacgtt
     2401 gagatgatcc aaccagagaa aggtgtcaaa gaatttgact aagaataaat ggcagacgct
     2461 acctatgctc atttggatag cgtcagatct tttattttaa ggatgatttt gtgtttttta
     2521 gacaccgtaa tttaagtaac tctaactttt caatccacta tttacttttt ttgtattttc
     2581 actgtctggg tctcgaatag cgaaattact gatgagtctc tattaaaaaa gctttttcta
     2641 cttgaaacta tattgggtgg ttgctcagga aggtttcgat ttcttgaatt gcttgttgtg
     2701 gaccatttat tggaaaaacg gcttgcagcg tgcgtgcctg ctgacgaatc ttgggtgaag
     2761 aaacttcgcg cagagcaatc tgcagttttc tttcagtcac tggttttgtg agggcgattg
     2821 cgtttccgta ttttacacaa tagtcaatat tacagctttg ctcaaattgc atccccacac
     2881 cgataaacgg tttgccggat tcacaggcag tttggacggt cccttccccg ccgtggataa
     2941 aagaaaaatc aatgaattca tgcaaaagat gactagacag atattctgtt attaaaagat
     3001 cttctgagtc agattgaatg tcatcaagca gatagtcaat aggtgcaata accgctagat
     3061 ccggttgttt ttgtaagaag aacaaaattt tgcgtaacat acgcggattg cctgaactac
     3121 ccattgcgaa atagataata cgttttcttt cttgttgctt tcgctgtata aaagttagca
     3181 cttcttcagg caaggaagta ctgagcttag caaaaattgg accaacgatt cgataatttt
     3241 ccggcagctg ttcttcttcc aaaaatagtt taggcgttgt gatgagattt agatcagcat
     3301 ccatcatttg taaacttgtt tttggtaaag gaagcatttc tttttgtgca gcgtgtttga
     3361 aggcattggg gatccatcgg gtatttacta tacgcttttt tgtccagtgc caaaggggat
     3421 tgcttaaagg gccgaagaaa cgtaactcgt ggggcatcag cgcatgctct gattgaaaaa
     3481 aaggttcact caaagcatag ggtttaacat atactaaagg aatcttttta ttgcgggccg
     3541 ataaaaaaat tgtcacattc gaacctgtca caatcagtcg aggctcaaac ttagcaatca
     3601 gactctgttc actagtgata cgagaggcaa ccatttcttt ggtaaaaggg tttttaagtg
     3661 tacgcaactg gtcaaatttt atgatttgtt cttcttgttt tttcgtaagg atcggcgcta
     3721 gtaaatgata ctcaaagcca ctttctgtga tcaaaggagc aaaagtttta gaaaagccaa
     3781 agaatacaca gtaataacgg tctttcatag ctttggcaac ctcaatcatt cgtgttgtct
     3841 cagctaaatt gaatactgca ggagcaaaaa gaattgtctt catgaaatcc tccttattgg
     3901 aatgagtcta tcccttcgtt tcttactagt atactaaaaa acacagcgtt cgagtagcct
     3961 atgtatattt tgaatattaa actgtctctc gctgttttca caacttctaa atttaaattt
     4021 tgtaatcaag ttgaaactcc aattttcaaa aaaacacgca acaatttttt gatcgattta
     4081 tatgttgtgc cagataaata cgagaagttg tgtcattaaa aataaacatg agaacataaa
     4141 aaaataaaat aattatatta attgataggt gtgctgtcgt cattatacac acgtaagaaa
     4201 gaaatagtta tgtttaaaaa tattcttaga ctttctcgcc atgaca
//
LOCUS       DACGDM010000152         4162 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.160, whole genome shotgun sequence.
ACCESSION   DACGDM010000152 DACGDM010000000
VERSION     DACGDM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.160"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            1..621
                     /locus_tag="IXR05_002767"
                     /pseudo
     CDS             1..621
                     /locus_tag="IXR05_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1069..1515
                     /locus_tag="IXR05_002768"
     CDS             1069..1515
                     /locus_tag="IXR05_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261207.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            1517..1654
                     /locus_tag="IXR05_002769"
     CDS             1517..1654
                     /locus_tag="IXR05_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4261208.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIINKDKSA
                     S"
     gene            1691..1984
                     /locus_tag="IXR05_002770"
     CDS             1691..1984
                     /locus_tag="IXR05_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261209.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            1981..2205
                     /locus_tag="IXR05_002771"
     CDS             1981..2205
                     /locus_tag="IXR05_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4261210.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            2202..3221
                     /locus_tag="IXR05_002772"
     CDS             2202..3221
                     /locus_tag="IXR05_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4261211.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLSDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            3410..3483
                     /locus_tag="IXR05_002773"
     tRNA            3410..3483
                     /locus_tag="IXR05_002773"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3444..3446,aa:Ile,seq:cat)
BASE COUNT         1433 a          728 c          838 g         1163 t
ORIGIN      
        1 ttactagatg acccttactg ggtaggtaaa acatcgttgg gtgagaatat tgcaaataaa
       61 ggtacgacgt tcccaattaa atctagcgcg tacgaaatat ataaaggtaa cacggaagaa
      121 gagcttataa taggtcaaac gtatactatc acgcttaaag gaacaaaacc cgcaagtcaa
      181 acctttgtag catataatta ttggaacgtt aattttggag aactaaaacc agttgaggga
      241 ttgacagacg tatggtctct aacattcaca ccaacgaaac ttgaaccggg tttgcctaaa
      301 gaccttcgca tttttcagtt gcctaaagaa acggccggcg catgccaaat tgactggctc
      361 aaaattgaaa aaggcgacac ccgaaccccg aatattagtc agtttaaata ctttggtgaa
      421 ggattgaaag atagcaacaa tccgaacgac tacagctggg acatcacgcc tgaatatact
      481 gaaaaaggct tgaatgatac ggttagtttg actgaaccgc aatccatcga aggattgaaa
      541 aatttcgaag atggtattca atcaaaagga aaatctgtat tgacatcaga cgacaacaaa
      601 tatgaagtcg taaccttaac agttacaaac gggaataccg gatcagcaaa gctttatcgt
      661 gaaggaaaaa ccgtcactat ttattttttt gcgttgaatg ggaaaagcag tggtggaaat
      721 gattcaacga tactaacaat tccagaaggc tatcggccac caattagttt tgagcaactg
      781 gttggctcga tagaccgttc tactttgaac agtgctcagt tatctattgg tgcagatgga
      841 gccattaaat ggcgaagaaa ctcaagttat ggatcagctt attcatttgt tatcacttat
      901 tcaatttaag ggaggaaatc taatgaaagt agtttacaaa tcaatcaagc cttacggatt
      961 cgagcaaatc attgtgaatg acgaagaaca tttaccggaa gaatgcacag aagtcgaacc
     1021 accgattcca aattggaaac cgaaattcaa ttactgggag ggaaataaat gaaaaacatt
     1081 tggaaatatg gccgtactgg cggagagtat gcaggaaaag tattggacga catgcttgta
     1141 tccgttcctt acacagatca gccaccgctc gaaggggttc gttcagatgg cgaaccgcta
     1201 acgattgctg atcagatgtt tgatcctaaa ttgaaccaat ggattatttt agcgaacgcg
     1261 ttagatcaca acgatttaaa caatctcaaa gcgatgtacg aggctcttga acatgaaaac
     1321 ggcaacctaa aacagctaaa tgccaaactc atgctaagcg atgtagcgat taaacaggaa
     1381 aatactgcat tgaaagaaaa agctgacagt ttagcacaaa tcaattcaaa aatgatgctt
     1441 gcttcgttac aaaatagcaa agacatttca gaaattaaag agcaactaaa tccagcttca
     1501 aaaggaggtg agtagtatgt ttagttttag cgatgtgaaa atgatgtatg attggggctg
     1561 ttttactgac gatcaagttc gactattcgt tccactatgc attacagacg aagaagcaga
     1621 taaaatcatt aataaagata agagcgcatc ttaattgatg cgtttttatt taaggtaaag
     1681 gagttgtcac atgattaatt taggggaatg gggaatgata gcaggatcaa taaccgctat
     1741 cgtttctttg attttattag taattagacc gattgctgca tctttctcga aaattactga
     1801 gactctttca aaagtaagcc acaatttaga tttgctgact aaagatttag aatcgagcaa
     1861 atcagatcga ttgatgattc atgaagaact aaagaaacac gatgaaagat tagatacaca
     1921 tacagaaaaa ttggtggaac acacgcaaca aatcaaaact ttgtttaggg agagaagaaa
     1981 atgaataata aaacgttcga agtactaaaa tggttcgcac tggtaattat tcccgcacta
     2041 gctactttcg tggggttagt tggtaaagcg ctcaattggc agtacacaga tatctgtgtt
     2101 gtcatcatta ctggttttgg cgcgttttta gggagtgtgt tgggtgtatc aaatcgaacc
     2161 tacaaaatgt tctcggctga aagcgaagaa ggaggaaaca aatgaaaaag aaaattacta
     2221 ttactgcgat gagcctgtta acggctcttt ttttattgcc aattaacgga tttgcctata
     2281 ctatcaacaa tgaatttaat ttgggcgcaa atgaaggtag ctcacaagta gcaaataatc
     2341 agtatatttt actgcatgaa acggctaatg aaacagcaac aggacgcaat gaagcgcagt
     2401 atatgcaacg ttcatggact agcgcttata ctgcttatat tgtgggagac ggcggaattg
     2461 tttaccaagt cggacaacct ggttatgtac agtacggtgc tggttcatat gctaatgcca
     2521 atagtcctgt gcagattgag ttacaacaca cacatgataa agcaactttt gaaaaaaact
     2581 ataaagcata cgttgaattg gctagagatt cagcaatgaa atatggtatt ccattaacat
     2641 tagacacgcc ttataaccaa ccaggaatca aatcacattt atgggtaact caaaacattt
     2701 ggggcgatca cactgatccg tatggatact tatcagaaat gggtgtaagt aaggaaaaac
     2761 tggcttacga tttagctcat ggatttacag acgaaaaccc aacgacttct gagaacaagc
     2821 ctgtcattga tccaacccga gcaggtgcag caaatccaac tttatcagat ggaacgaacc
     2881 attctcacat tgatcagttt ggagaaatcg aaaatgcgaa cttacacgtc gctggatggc
     2941 acatcgctaa ctataagtac gagtatattt tcattatgga ctacaatact gggaaagaat
     3001 tagctcgagt aagagctgat ggaatttata gaccggatgt aaatcaagct tataatactt
     3061 ctggaaatgt tggctatcat gtatctttta acatgcgtaa cttccctaat aagaaagtct
     3121 atgtcatgat gcgggcaacg aatgatccag agggaaacac taaaggcggt gcgcaagatt
     3181 tccatgacaa acgttggtat ttaaatattc ctaaacgata aaaatagctc ctcgttgagg
     3241 agcattacat aactatattg acaactataa aaatcattcg ataaaatagt gatgttatcg
     3301 catatcttca ctatcaccca taatagtcac actccaagct atgcgataac aggtttgttg
     3361 ccacacattc tactggttga ttgtttatgg ctttatgtgg caacaaccag tacccttagc
     3421 tcagttggtc agagcagacg gctcataacc gtccggtcgt aggttcgagt cctacagggt
     3481 acattaacgt agccatttga atcgttctgt gttagaattt ttttgaagag tattatacaa
     3541 gctaaagctt ttcttcattg ccactcaaat gagtggcttt tttatgtatc cttttatgga
     3601 ttaatgaaag gatgtttcac atagttatac ttctgtatat ttgaaaagtt ttactttgat
     3661 ttttaaatag aaagacattt gggttaaatt gtgagataat aataaagaag agtttaaagc
     3721 gcaccccaaa ccacttcccc ataagtgtgt tacgctttaa actcttttat atttgaagcc
     3781 attaaaaagc ataccatatt tttgaaaaaa agtgagaaaa aaggcttaca attggagtgg
     3841 tagttaatta gtgacttatt tttgatttta tagcactgat actataaaat atagatatca
     3901 tcatattaca caatcttaat actaacttaa aaaatatctc ctttcacaag tatggtgata
     3961 aaattcgttc cgggctacct ttttaggtag cctactttaa tctttatacc tttctggatc
     4021 aacgaaagta tactttatat agtcataacg ccgatgatcg ctacgtgcgt ccggcacgtc
     4081 agtcatgaat cggctacact agactagaca gaaaaaataa ggtgtgtaga ataataaaaa
     4141 acacactgga ggatttttca tg
//
LOCUS       DACGDM010000153         4099 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.161, whole genome shotgun sequence.
ACCESSION   DACGDM010000153 DACGDM010000000
VERSION     DACGDM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.161"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..671
                     /locus_tag="IXR05_002774"
     CDS             <1..671
                     /locus_tag="IXR05_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAQ4261212.1"
                     /translation="LFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEK
                     NYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKE
                     IGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYN
                     YISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNF
                     NNIS"
     gene            688..1122
                     /locus_tag="IXR05_002775"
     CDS             688..1122
                     /locus_tag="IXR05_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261213.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            1739..>4099
                     /gene="esp"
                     /locus_tag="IXR05_002776"
     CDS             1739..>4099
                     /gene="esp"
                     /locus_tag="IXR05_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAQ4261214.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTV"
BASE COUNT         1503 a          569 c          784 g         1243 t
ORIGIN      
        1 atctgtttct ttatgaaaat aaaatactgg aatatgttaa aaatggagat attcgaaatt
       61 tagaaaacat ggtttttaat ctgagtaatg gaataattcc aagtgttagt ggagatacga
      121 ttcggtctga aaaaaattat tctatcattg tttttgaaaa gttagcacaa acgtctataa
      181 cattaggaat ggatataata gaagcgtatc aaagtagaga tgctttgata caagaaaacg
      241 aattagctgt atcgttacct gaggtcttaa aagtgaggga ttctgggatt gtttattata
      301 ctaaggaaat cggaaaaact aagatagagc atctttctcc cttaatttct tctgtcgttc
      361 aattcatcgg cttaaatatc tataaaagaa ttactgtaaa ggaaatagct aattattttt
      421 ctgtaagtga aactaaatta agagaaagct ttaagaatga aatgcatatt acgatttata
      481 attatatctc taagcgaaaa atttctacgg ctaaaataat gttgaaatca aaccatacta
      541 tcagtgaagt ttctttaggt ttaggatttt cagattcttc acacttttcg agagtattca
      601 aaaagtacgc aggtgtatct cctaagcaat atcaattagg tttagtggac aatttcaaca
      661 acattagctg agaggtttta ttttattatg agactatatc atttacgtag tttggaggag
      721 ttgaggaaat tggattttaa caaaaaattt ttttgggaaa tttctgattt gagttgtttc
      781 gtagaatctg agcgtctaag taatggtaat aatagtgtgt taaatgaata tgacaaagta
      841 gtaattaata aagtaaaaag tttatgtgaa gaagctagag aatctatcag tcatattaat
      901 ggtagcaatt ttaaacaaac attatttaat ctgattaagc tagatgctaa aatatcaagt
      961 tatttattct ttttgataca tgatgaattt atggattatc aaaaattgga tcagttaatt
     1021 gaaagagaaa gctgggaaga ttattacgtg ggtctaactt tttcagaaaa gttaaacaac
     1081 tacaagttaa tagattataa gtatttgagt gaaagcaatt aattattcat gtagagtact
     1141 agacacttta aatatggaca attcaattat aaagaaaaag aatcaataat ttaatgaggc
     1201 tgtgacaaat gtcatttttt gtttcgctaa aaacgagtga aaaaatgttg ataactccaa
     1261 tcattcgttt aagattctag gaatcattca gaaatgctgt gaaaccgata ctttataatt
     1321 ataaagaagg tgatttcaaa ttccgaagaa ggaatttgaa gtcacctttt tacttatgtc
     1381 acagtctcat tcagtaatgc gggataaggc tccttattcc gttatttgaa tactctgaag
     1441 tttaatctaa gaaagggtaa tattttgaaa acatgcttca tcgcatagaa atgaacttaa
     1501 tttcagaaag aatacataca tatcttttta tatgttttca gctgctgaat ggttaaaaag
     1561 cacaaatatc cgaaaaaaac atgaagaaat gtactttttt tgttgtaatg ttcatgaaat
     1621 tctctaagta aattagttaa cataaggtta gtaagattcc tattctgtga ataatacgta
     1681 tcagatttat cttttattct tactaggaaa gtaattatta agggagttga tttgaataat
     1741 ggttagcaag aataataaga gagtatttct agaaaaaaca aagaaacgag tattgaagta
     1801 cagtatcaaa aaattaagtg ttggggttgc atctgttttg attggtgttg gtcttgtctt
     1861 gggaacaact gaactagtta aagcacaaga tgaaatttct ccaagcagcc cacttgaaac
     1921 agcgataagc tccgtacaag taggtgacaa agtagcttcg gggaatactt ttcaggagaa
     1981 tcctggttat acgaaaaatt ataacttttc ggatttacaa tttagtcctc aagaactaac
     2041 tggagacaca ctaaaaggca atacaattgg atttgaagtt tacggaaaac ataatattgc
     2101 agcatcaact aaaaactggg aaatccgtct tcaattagat gaacgattag ctaaatatgt
     2161 agaaaaaatt caggtcgatc caaagaaagg aattggatct tctagacgga cctttgtaag
     2221 aattaatgat tcgctgggta gacctacaaa tatttggaag gtcaattata ttcgtgcaag
     2281 tgatggatta tttgctgggg cagaaacaac cgatacgcaa accgctccta atggggtaat
     2341 tacgtttgaa aagagcctag atgaaatttt taaagagata ggcatagaca atctcaagac
     2401 cgatcgttta atgtatcgaa tctacttggt aagtcatcaa gacgatgata aaattgtacc
     2461 gggtattgat agtacgggct actttttaac agattcagat gatttctata atagcttaga
     2521 tgtatctgaa aataatcctg accagtttaa acatggatca gtaagtgcaa aatatgagaa
     2581 acctaatact caaacaaaag atggttcagg atccacaggt gctaatggag ctataatctt
     2641 agatcataag ttaacgaaaa attataattt ctcatattca tcttccgcaa agggcacgcc
     2701 ttggtatgct aattacaaaa ttgatgaacg attagttcca tatgtagcgg gtatacagat
     2761 gcacatggtt caggctgaca aagtaacata tgatgtttcg tttgaatccg gaacaaaagt
     2821 agctgattta gcaatcgagc gacgggaagg tcatgaaaat tatggcatag gttcaataac
     2881 taataatgat ttaactaaac ttatcgattt tgctaatgca agtccacgtc cagtcgttat
     2941 tcgatatgtt ttacaattga ctaagccatt agatgaaatc ttagaagata tgaaagcaac
     3001 agcacaagtt gaagaaaata aaccatttgg tgaagatttc atctttgatt cttggttgtc
     3061 ggatacgaat aaaaaattaa tccagaacac ttatggaaca ggttattatt atttgcaaga
     3121 tattgatggt gatggaaacc ctgacgataa agaagagagc ggagacacga atccatatat
     3181 cgggaaacct gaattagaag aagtatatga tgttgacaca acagttaagg ggaaagtatt
     3241 catccacgag ttagcgggaa caggtcacaa agcccaactt gttgataaag aaggtactgt
     3301 attagcagaa aaaactatcg ctccaaatga aaaagatggg gctccaattt cagatactgt
     3361 agaatttgaa tttacgggtg tagattcaag taaattaatc gcgaaagatg aattaaaaat
     3421 ccaaatcgtt tctccaggtt ttgataaacc agaagaaggt tcaaccgtta ttaaggaatc
     3481 accaaaagcg gttgataaac aaaccgtggt agttggattt aaaccagatg ctaaagaatc
     3541 aattcggaat aataaaaact tacctgaaga tgcagagtat tcatggaaaa cagagcctga
     3601 tacttctaac gttactgata gtacgaaagg tattgtaact gttaagatcg gaaatcgaac
     3661 tttcgacgtg gatgtagagt ttgctgtaaa agcttctcaa gctatggaaa atgatgcaac
     3721 atacgtacct ataacaacaa ctccagaaac gacagttcaa agtggaaaac ctacatttga
     3781 taaaccagat gttcctttag ctaaagatgc cttttcaatt tcagatgtct ataataagta
     3841 cttcggtaat gcaagtgttg atgcaaacac tggtattgtt acattcactc cagctaaagg
     3901 tgtaggagaa tcggagccga ttactggaac aattcctatt aaaattgttt accaagatgg
     3961 ttctgtaggc acgaccgatt tagcagtaac tgtaagtaaa gatatttatg aaaatccagg
     4021 agaaaacatt cctgcaggct accacaaagt aaccttcacc gcaggggaag gaacaagtat
     4081 tgaaagtgga acaacagtc
//
LOCUS       DACGDM010000154         4097 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.162, whole genome shotgun sequence.
ACCESSION   DACGDM010000154 DACGDM010000000
VERSION     DACGDM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.162"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(209..1714)
                     /locus_tag="IXR05_002777"
     CDS             complement(209..1714)
                     /locus_tag="IXR05_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4261215.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1711..2397)
                     /locus_tag="IXR05_002778"
     CDS             complement(1711..2397)
                     /locus_tag="IXR05_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4261216.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2590..4011)
                     /gene="gndA"
                     /locus_tag="IXR05_002779"
     CDS             complement(2590..4011)
                     /gene="gndA"
                     /locus_tag="IXR05_002779"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAQ4261217.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1130 a          861 c          695 g         1411 t
ORIGIN      
        1 atttttattt attattttta aacacgaata ttacagcatt ttattgtttt ttcgttcatc
       61 taaaagatac ttacatttaa ttaacggatg ttattctatt taattgttcg ctagtttttt
      121 tataatgaca tccctgaatt tctcacttgc ttgtattttg taccttattc tttgttggat
      181 atataaaaaa acaagtaaag cacatgcttt acttgtcttc tgcctttgcg ataggaataa
      241 agattctaaa aattgtccct tgccctacta cactttctgc taagatacgt cctttatagt
      301 tttcaaccag ttgtttagcg atagacaacc ccagaccatt tccacccttc gttctagctc
      361 ttgctttatc cactcgataa aaacgattga agatcttatt aaggtcttct ttgggtattc
      421 cttcgccaaa gtcctgaatc gcgatctcaa attcattcag agtggaagaa atagagatat
      481 ggacttcttt tcgtgtagtt gaatacttta ctgcgttatc caatatgata atgattaatt
      541 gttcaaagtg attacgataa atttgcaggg tcacttcttt tgtcaaatca tcatctaaag
      601 tgatcacata gtctggatat aatatcttga aattattata aacttgatag gtgacttctt
      661 ttcctttagt tgtttcattc gcataatgaa catctacttg ttctgctctt gataagtcta
      721 gcatctcttg aactaagctt ttcatacggc tgatttcttg catgctggcg cttaatgatt
      781 cttctaatat ctcaggatca tctttccccc aacgatttag cagactaaga tgcccttcaa
      841 taattgcaac aggtgtcctt aactcatgag atacgtcttc cacgaattgc tcttgttgtt
      901 caatatacaa acgcatacgg tcaagcatct cattgaatat ttcagctaaa tctgccaatt
      961 catcatttgt gtcgatttca ggcatgtgga tatctgattg cggatcttta cgtatagtat
     1021 ccattgtatc tctgagtacc ttgagtggtt ttaagaaata agaagataaa aagaaaccta
     1081 aaatactact taagatcaaa gaaacaactt ctaaaacaat aagagtcaat aatagcttat
     1141 ttcgaatatc atagaaagaa gataattcat agaagctttg cgcatagccg atcttttctc
     1201 ttgtaccttt agaatatata ggctggatag ataaaaagcc agtttttcct tctagtgtaa
     1261 cgatcgttgg aactttacgt gtagtctgaa tcaggtttcg actgttttca tgggttttaa
     1321 aaatcaagtt ctcgtccaaa tcataaacat aaagatccat tgatggctgc cctagctcag
     1381 ctataaagga atcgatcttc attaagtttc cttcgaccag tgaagtatga tctacgacct
     1441 catctccgtc atttgtcgct ttcgtcagat tacgatacgt atttactaat gtcagttctt
     1501 catccgagtt agccaaacga gaagctactt ctgaaatcgt acgctctaca ttgtttcttt
     1561 cttttgccac aatcagattg atagatgatt tataggtaat gacagcgaaa attgtaaaca
     1621 caacgaatat gaagaaagaa ctcgcaaagg cccacttgat tgtcaaggag ggccctttca
     1681 gttctctttt ttccgatttt ttcggcttta tcacgagcgc atcacataac ctgttccgcg
     1741 tacagtttgg atatagcttt cctccccggg aacgtcaatt ttgttgcgaa gataacgaat
     1801 atatacgtcc actacgtttg tttcaacttc tgtttcgtat ccccacactt tatttagtaa
     1861 aacgtcacgt gctaatacca cgttcacgtt ttccattaaa gtaagcagca actcgtattc
     1921 tctttttgtt agttcaatta cttcatttcc gcgacgtacg acacggtttt ctttttcgat
     1981 agtcaaatcg cgataagtaa tagtagtttg tttagccaca tttttatcgc cttcaatatc
     2041 gattcgacgc aacaatgcac gaagacgtgc taataattct tcgatagcaa atggtttgac
     2101 gatgtagtca tctgctccgt ggtcaagtcc agatacacga tcgatcacag aatctcttgc
     2161 agtcatcata atgattggtg tatttttgac ttggcgtaca cgtctgcaga cttctaaacc
     2221 gttcaattct gggagcatca gatccaacaa tatggcatcc cactcattat ttaatgccgc
     2281 atctaaacca gttcggccgt tgtagtggac ttctgcgtta tacccttcat gcttcaactc
     2341 tagctcgaca aatcgtgcca agttcttttc atcttcaatg attagaatat tgctcattta
     2401 ttattttatc ctttctattc tactggcttt ttaaaaactc tatcattata ccgataatat
     2461 gcttaaaaat ctatagtcat tttatcatgg atagcaattt taaaaaagag ctgaagtcta
     2521 ctcataacaa tcgacttcag ctctttcgtc ctctttttat tttctcattt cctaacagcc
     2581 gaaagactat tattcttcat ggtaccatga gtaatggaag attccttctt tgtcgacacg
     2641 ctcataggta tgtgcgccaa agtaatcgcg ttgggcttgg attatatttg caggcagacg
     2701 ttctgctctg tatgaatcga agtaagcgat ggctgatgag aaagtcggta caggtacgcc
     2761 agcttggaca gccaaggcaa cgacgtctct gactgattgc tgatattttt tcgtgatttc
     2821 aacgaagtaa tcatctagca ataaattttc gatctcagga tttttgtcat aggcatccgt
     2881 aattttttgc aagaatcgag ctcggatgat acatccagcg cgccagattt ttgcgatttc
     2941 accaaatggc aagtcccaat caaattcttt tgaagcgaca cgtaattgag caaatccttg
     3001 ggcataactc atgattttac tgaaatacaa cgcttctcgg attttttcga ccaattcttt
     3061 tttgtctccc gtgaactcaa aatcgttcgt acgagacaaa atcttgcttg cttgtacgcg
     3121 ttcttcttta taagcagaaa tatagcgggc aaatacagat tcagtgatca atggaagtgg
     3181 cacacctaag tcaagcgcgc tttggcttgt ccatttacct gttcctttat tcccagctgc
     3241 atcaaggatc acatctacta ctggtttacc tgttccttca tcgtctttac gtgtcagaat
     3301 gtcagcagtg atttctatca aatagctgtc taattcgcct tgattccatt ctttaaagat
     3361 atcagccatt tcttctactg aaaggtttaa aatattcttc attaagtcat aagattcagc
     3421 aatcagttgc atatctccat actcaatacc gttgtgtacc attttcacat aatgtccggc
     3481 tccatttggg ccaatatatg tgacacatgg tgctccgtct tctgcttttg cagaaatttg
     3541 ctctaagatt ggtgcaacta gcgcataggc ttctttttgt ccaccaggca tgattgaagg
     3601 tccttttaaa gctccttctt caccaccgga aacgcctgta ccgataaagt tgatgccaga
     3661 gttggctaac tcttcattac gacgcatcgt atctttaaag aatgtatttc ctccgtcaat
     3721 caaaatatcg cctttatcaa ggtgaggaag taactcttgg attgttgcat ctgttgccgg
     3781 tcctgctttg accattagca agatccgacg tggtttctcg atagattcta caaattcttc
     3841 gattgtatat gttgctttga aatttttatc tgggtgttct tctactacag cggttgtttt
     3901 agcccctgta cgattgaata aagccactga atagccgcgg ctttctatgt tcaaggctag
     3961 atttttaccc ataacggcca taccgacaac gccgatttgt tgttttgaca tatgaactcc
     4021 tcctacatac gggatttctc cctaatctct tacattatag cttaacacgg ctacattgca
     4081 aactaaagaa caacata
//
LOCUS       DACGDM010000155         4047 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.163, whole genome shotgun sequence.
ACCESSION   DACGDM010000155 DACGDM010000000
VERSION     DACGDM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.163"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(70..612)
                     /locus_tag="IXR05_002780"
     CDS             complement(70..612)
                     /locus_tag="IXR05_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAQ4261218.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            747..1136
                     /locus_tag="IXR05_002781"
     CDS             747..1136
                     /locus_tag="IXR05_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261219.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1140..1904
                     /locus_tag="IXR05_002782"
     CDS             1140..1904
                     /locus_tag="IXR05_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4261220.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2033..2980
                     /locus_tag="IXR05_002783"
     CDS             2033..2980
                     /locus_tag="IXR05_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4261221.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3110..3850
                     /locus_tag="IXR05_002784"
     CDS             3110..3850
                     /locus_tag="IXR05_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261222.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT         1350 a          687 c          815 g         1195 t
ORIGIN      
        1 aataataaat aaaaactgtc taacatttaa aatttaattt agatattaga cagtttttaa
       61 gtttgtgagt tattttcctt gtcgttttct cactttttta gtccagaaac cacctgaaat
      121 atattttggc tcataagaaa tgataaaagc acgctcttcg atttctttga tcaggcgata
      181 cagttcacgt tcgctttttc taggagaaag tatttcgaga actagccgct caccttccag
      241 ccccattgca gaagtctgtg tcacaccata accgtgttct ctcagtatac ccggcaaact
      301 tttatcttct gcgctatttg ctggcaaaat cgttgtgacc atgatgtatc ctaatgccaa
      361 tttgtcttca atcaaaattc cgacactgat acctactgcg taacctaacg catagacaaa
      421 taaattcagt ggattatcta aacgatctaa aacaagggat aagccgacga tataaatcgt
      481 gatctcgacc atactgacaa gtggagcaat cagtcgatag cctttcattg tcaacatgaa
      541 acgtaacgtg ttcagagtga tataagcaaa attaatgagg aagatcatcc ccaacatttt
      601 tggatcaatc atttgtaaaa ctcctttcat ttatataaca acaatatcaa aaaaaatcgt
      661 aagtgaagaa aaattgaaac tttatacata caaaaaaatg ataaaatgat tataatagaa
      721 ttataaagat aggttaggtg attaaaatga aaacggtcaa tcgtgtgttt tgtgccagcc
      781 acgtgctaag tctccttctc agtatatact taggtgtcta ttcgattcaa cagccaattg
      841 aggtagagaa cattgttttt cagatgtcgc tgacagatgg tttaatttta agcgtttttt
      901 tctttttgat actgtttatt ggtaatattt tcggtagcgt tgccagtttt ttgaattttt
      961 ctatttatcc actcctttcg ctagcattag gagtggtggg actttgttct ctgtgcttat
     1021 ttcccgagcc attcagtcct gcatttatat tatttggtac actgaacctg ttccagacaa
     1081 ctgttggagc atggttgcta tggcgatcag gaaatttaat gaaaataggt gagtaacaat
     1141 tgaatccaat tatattgaaa cgttctgtcc atcatattcc agtgttagaa gttgttctga
     1201 aagaattaag agaggaacgt attcccgttg tcatctatta tcacggatgg cagacaagta
     1261 aggagttagt tttgacgcaa ggaagaaaaa ttgcgcagca gggcattcgt gtgatcctgc
     1321 cagatgcgat gaatcatggg gagcgcaaac agccggtttc ttctattcca tcctatacat
     1381 tttgggatag tatctacgga aatctgtttg aatttgacac acttatcaag catttagaaa
     1441 aaagaggtct tctacatgat cagcttgcag ttggcggggt ttcgatgggg ggaatgacaa
     1501 catgcgcctt gttggctaaa catcctcata tagtagcggg cgtgtgtttg atgggttccc
     1561 ctgcaccttt ggaatatgga aaagaaatcg taaggcgcgc atcggaatat aattatgtcg
     1621 taccaaaaga ctattttgat ttgatttcat gggttaagag ctatgatttg tcattgcagc
     1681 cggaaaagtt agctggacgt cctctgttct tttggcatgg acaagctgac gaaaaaatcc
     1741 cttatataca aacggaacga tttgtagaaa aaaatcggca taagtcttac ggaaaagaaa
     1801 ttgtttttcg ttcctcaaaa acacagcgac atatggtaca aataccacta atggaagaag
     1861 cttccacttt tttagcaaaa aatttgataa aaaagtataa ataattgaaa cggaaaatca
     1921 ctcatgacga tagaggattt tccgtttttt attttgggct ataataaact ctgttaggaa
     1981 aatttggtat aattgatagt aagaatgaca acatgttaga aaggaagaga gcatgcccac
     2041 tttagcagat gttgcaaaac gtgccaatgt ttcaaaaatg acggtctctc gagtcatcaa
     2101 tcatccggaa caggtgactg acgaattgaa agagttagtt ttctcagcaa tggctgaact
     2161 ggattaccgt ccaaatattg ctgcaaaagc acttgtcacg aatcggtcgc agatcatcaa
     2221 attatttata ctggaagaaa tcgacacaac tgagccctat tacatgaatt tgctgatggg
     2281 aatcgctaaa cggatcggta aagcgcatta ttctctccaa ttagttacaa atgatgcctt
     2341 cgacgtcggt tcttgtgatg gatacatcat cacaggtgtc agaaaaaaag acttcgattg
     2401 gatcgaccgt ttggaaaaac cagttgtctt gtttggggaa aattctgaag gatatgatta
     2461 tgtagacagc gataatgaat atggtacagc aaaagcaacg caatatgcct tagaaagaga
     2521 ttatcaaacg attatttata tcggtatcga agtggacgag ccttttgaaa tttcaaggga
     2581 aactggttat ttatctgtga tgaaggaagt tgatcttcct agtaaaatct tgcggtttcc
     2641 aaatcattcg acagaagtag aaagatatat gacagaaaac tgggcagatt ttacagataa
     2701 aacttgtttt gtatgtagtt cagatcggct agcactagga gcagtaagag ggattataaa
     2761 tgctggagga cacttgcccg aagaatttgg tgtgattgga tttgatgggg tatttttaga
     2821 ccaaatcagt tcacctaaat tgacaacgat caagcaagat attatacgta tgggtgaagt
     2881 atgtggagaa atgttgttaa aaaaaataga agaaaaaggg gcgagtcaag gttatcgtcg
     2941 tttttttcct gaactagtta tcagagagac aacgaattaa gtcttattac tatatatata
     3001 tttatgaaat tcatcgctat tttcttaaaa taatcagcgc attgctactg aaaacaatga
     3061 atctgtgcta ttattgagaa aagttccatt tttgagaagg atggtttgaa tgaaagaaat
     3121 cagacgaaaa catttccgtt ttcctgcgta cgatgatgag ttaggcgtaa aattaaccaa
     3181 cgacaagaag cgagtattat ttgacggaca agaagatctt ttgactgaac agaatcagtc
     3241 cccgtttgaa cagatgaaag aatttcattt cacgaacacg aacaccgaga aaatccgtcg
     3301 caagcgtcgt gcaacaaatg gattgaagtc agctccgcgt aaggaaaatt tggaaaagca
     3361 taaaggaaaa ttaccggatt ataccggcca ttaccaatca gaaatcacat cgacaggacg
     3421 aaaaaaactt tttggtgatt cctctcgttc tgtcagacaa agtgaaacaa ggacagagtc
     3481 caagcatact acacgaaacg catctgttga cacgaaggtg cgggagcgtt cttattttgt
     3541 tcctaaatat gtacccgcat cgattatccc agaccctaga gaaagcaaaa tttctgagga
     3601 tcatttaatc gaatcgatga aaaaaacgga tgactcttat ctgttgttcg atacagaacc
     3661 gacgccgtat caagaaaaaa gaaatggtga gccgtctgta cgaacattca atcgaacaaa
     3721 aacgttagag gaaacaaagc agtcagaaga aaaaaaatcg aaaaaaagcc atggtatctt
     3781 agaacgctca ttacaaggat tgatcgatga tcaaggaaac tctttgggag aaaatagcta
     3841 ttttaaataa gtgatataca aatttatatt cggctacagt tggaaaggaa acgctgcggc
     3901 gtttccttat tttatactct atccgaaagt ttatatcgta tcctcaaatt tttttgagtt
     3961 taagcgaatt ttttctccca ataagtaaga aaataatggc aaaataaaaa aacaaactat
     4021 tttcgcagat cgtttgcaaa aatagtt
//
LOCUS       DACGDM010000156         4008 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.164, whole genome shotgun sequence.
ACCESSION   DACGDM010000156 DACGDM010000000
VERSION     DACGDM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.164"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            825..1037
                     /locus_tag="IXR05_002785"
     CDS             825..1037
                     /locus_tag="IXR05_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261223.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1315..3114)
                     /locus_tag="IXR05_002786"
     CDS             complement(1315..3114)
                     /locus_tag="IXR05_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4261224.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3238..3834)
                     /locus_tag="IXR05_002787"
     CDS             complement(3238..3834)
                     /locus_tag="IXR05_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4261225.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1435 a          709 c          686 g         1178 t
ORIGIN      
        1 aatattatca tcgaaacagc taacaaaatt gtcataaaaa acgagatggt tgatattaga
       61 acttgtgttt ttgtttaggt ctagagataa agagagacaa tttccaaata tatgtaatga
      121 atacaaaaag acgtttgtcg cggattaccg ttacaaacgt cttttattga ttttccgaga
      181 tctcatcagt cgccatttgg aatggttcac tccttatcta gattcgttta atgctcggac
      241 tgcttgttcg attgtaatac caaacgcaac gttattttcg ttttgtgcat caatcgccat
      301 aaaacggtta gaagttgtat caaaagctac gcggtattgc atatttgttt ttgtaaacgt
      361 cataaaattc atctcctttg taatgtaatt tagttcttga aagtttcctt taaactttcg
      421 aacttatacc aagtttagca tcgtacgttt tttgatgcaa ttaaaaagca tttatcattt
      481 tccttattta ttttttctta aatggtttag ctattttctt ttaatccgat aagtagccca
      541 atcatcaagg ttacaaatac tattgcttga atataaatca tatgctcacc tctttataaa
      601 taacttagca atataaagaa aaaaacgcac gaacaacata ggaatataaa caaacgtttt
      661 tgtcacaacg tctaagatcg tgttaaaaaa tagttatcta aaaagcagaa agatactcaa
      721 aataaaaaat aaaaaaatgg ataaaaacgt tttcaaatac aaggtaattt gttattataa
      781 aataaagaaa aaacaaaata aaaataaaga aaagagggaa tgaaatggta aaagcagaag
      841 taggaagatc ttatatatgc aaaccgatcg gagtatctca tgaactaatc ggctgtattg
      901 aacgtacata tatcaacacg gctgtcgtgt atgttgaaag ttatgaccaa cgagactatc
      961 aacttatcaa tgaaagcaag tatcgcatgc tcgtaaaatt ctgtgatatt agcgcacctg
     1021 ctgaattggt ttcttaaaca gtatttttga gaattcgcaa gaactccctt ataatataaa
     1081 taaagacaga agggagcgag aagatatgcc aaaaagaaaa agttcaggga aaatgggaat
     1141 tattcttgca gtgatctctg caattcctgc tattttagct attgttcgtg cgatgaagga
     1201 atcaagagaa agttaagcac acattatgag cgtcaaacaa aaaacgcata tacctgcggt
     1261 ggcaggttat gcgttttttg ttgtataaag acttttttca ttaacgattt ttgattagcc
     1321 gactcccaaa acaaaattta gcagtttatc tgaataagtg atttcttcat ctgtttgttt
     1381 cacactttca tttagtagtc ccatctcatc ggttatgata ccatccacac cataaaacat
     1441 catgcgactc atagcatctg aatcgttgat tgtccataca tatacttctt ttccgtcttg
     1501 gtgggcagaa ttaatgaagt tacggttgat cgtactatat tccattgtca gaaaatcagc
     1561 aggcgtcaca gggggcccaa caatattgaa aggtaagatg tagcccacat aaaagtttgg
     1621 ttctgcttct tttaaatctg aaacggtttg gtacgtcaaa ctttgcaaaa tatgatggtt
     1681 ctctaagata actttgcggt atttatggac aaatcgttcg acaaggtcat ccgaatcttt
     1741 tttagaggtc ttgatctcaa taagtaattt ttggtttagc ttatgtgctt tttccaaata
     1801 agaatcaaaa gaacaaacag gggcttgcac tccgttttca gtaactgtaa gatttgtcaa
     1861 ttctttcaat gtaagatcct gtggtgttcc atttacccct gttaagtgac gaagatttgc
     1921 atcatgcatc actacgaaat gaccatcttt tgtttcctga acatccatct ctacataatc
     1981 aggatgatag tctctgcttg ttttttcaag tgcttctaaa gtattttgcg ccccattttg
     2041 ggtactcaca cctctgtgag agacagtcac tggttttgtc tgaacagctg aagtcagata
     2101 atccatattg taaagacaga cgccaatacc gaaaaaaact gcaaaaagag tcaaaccagt
     2161 gtttttcagc gcagagaaac gcaagttggg ggcttgtggg ataaaccact tagggatctc
     2221 aggcaagaag ccttcgtcat ccatgaaatc aacaatgata taaaaaatcc ctacggtaga
     2281 catcacgata ttgaataata aaatcccttg taaaagcgtc atagcaaaca cagcgctgat
     2341 caatgcatag tctgggaaaa attgttcaac catactttgt gccaaaataa caacgatata
     2401 tcctaaagaa gaaaggagta aaatcgtacc gccaatcaca ataaattggc ccgtgatggc
     2461 caaaagacgc gatttggtca atgaccagct ttcccgaatg gctgctcgaa aaggacgatc
     2521 tcgtagaatc atttccggta aagcaaaaat cagtcgaatc ccaatatagc caaggaaaat
     2581 ataaacgagt aaaaaggaac tgacgatgat ccaacgatta gcaaaaataa aatccataat
     2641 gaaagcgggg atttttattt ttgacagtag atcagaatta aaacttaatc cgctgatcgg
     2701 tagaatcaat aaaaaataag caaggaaaaa caaaaaagta atgggtctca ctttcttcag
     2761 ctgaagtatc gtcaagtgta agagttgctt caaagagatt ggttctttct ttttaataaa
     2821 aaaaacactc atcaaaagaa aagtaaattc gaaataaact aacagtaaaa tcgtcatcaa
     2881 aactacgatt aacgagagta gaaccccagg atgttgagaa aaaattgaag gaatattgtc
     2941 ataagacaaa tagtcaattg cccctcggtg taaaataaaa cgggtcgtac tgctcaataa
     3001 gggtaaacaa ataaataaaa taaagccatg catcagcaag acatcacgga aataagcttg
     3061 tgttcctttt aaaaagtccc aagcattacc taagctacgt ttcaaataat tcatcctatc
     3121 acctgctctt cacattgtag cgcaaatcta atgaaaaagg aaagggtgca gtgtgttttg
     3181 cagacccttt cccagattta acattgtcaa tcaatgacta attttacaaa ataaatatta
     3241 tccaagaaga ccacttagat attgacctcc ataaatcaag gccatactat ataagaaaat
     3301 cgacagtggt ttagcaatca aaatgattag tgtatatcgt ttcactgaca tgtttgtcaa
     3361 tccagccatc aaacataacg catcgtcagg agcaactgga agaaaaatag ctagagcaaa
     3421 cagcttctca aaacggtttt gattatccag ccagccaata tatttgttat atgtcttatc
     3481 gctaatcatg gaaagtatga atggctttcc ataacgacgc cctagcagaa aaatgataat
     3541 cgaaccaatg cagattccaa tatagttata gataaatcca gcataagggc caaatatcag
     3601 gacaccagct gcagtactga tccctccagg aatgattgga ataactactt gcaggatttg
     3661 gatgaagaca aaaataatcg gtcctaaaat gatggaatca cctactaatc ctcttaacgc
     3721 attcaaatct ttgaaaacac ctaaattaat aaaataaatc gtcagcgcga ttgataggcc
     3781 taatccgata atggatatga aatttatcag ttttcgagag gcagcaatat tcattattca
     3841 tcaactcctt agaggttctt tgttaactat actttactag aaaagcaact aactgcgcca
     3901 ttttttgata tgacagaaaa caaacaattt tgtaagttca tcataagtat aaaagattga
     3961 tctcaaaaaa acatccaact aaagacttat ttaataactt gttttttt
//
LOCUS       DACGDM010000157         3904 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.165, whole genome shotgun sequence.
ACCESSION   DACGDM010000157 DACGDM010000000
VERSION     DACGDM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.165"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..1482
                     /locus_tag="IXR05_002788"
     CDS             <1..1482
                     /locus_tag="IXR05_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261226.1"
                     /translation="GKPNLMSKLKSSDFNVGYHGSLTSDNEKLHFTSDGTGSIIMFTR
                     INTPQLASGKTYTLSAKVRFDEGTTGAIDKLRLVYRTSPGEKILLEANSTNITTDDVG
                     KEITIKGTANVNYQITNLDRFYMSISFVDRDKINGGFKLYDIKIEEGSTATPYQPNLL
                     DAPYYLSKVALGENLIKPESQQPVTNSNYLINTYNIKPMVKGKKYTITLEGTKPATQV
                     FRPFFTRATGDAWEVGDLQPVEGLTDVWSGTFTAAADPHPTSPQVQICQVPSTSLGNC
                     TIKWLKLEEGDTRTPNIEQYKYRGIGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEI
                     TGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDT
                     ATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGRSSGGNDSTILTIPEGYRPPISFEQ
                     LVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYTI"
     gene            1645..2091
                     /locus_tag="IXR05_002789"
     CDS             1645..2091
                     /locus_tag="IXR05_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261227.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            2093..2230
                     /locus_tag="IXR05_002790"
     CDS             2093..2230
                     /locus_tag="IXR05_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4261228.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            2268..2561
                     /locus_tag="IXR05_002791"
     CDS             2268..2561
                     /locus_tag="IXR05_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261229.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            2558..2782
                     /locus_tag="IXR05_002792"
     CDS             2558..2782
                     /locus_tag="IXR05_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4261230.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            2779..3804
                     /locus_tag="IXR05_002793"
     CDS             2779..3804
                     /locus_tag="IXR05_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4261231.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
BASE COUNT         1385 a          664 c          805 g         1050 t
ORIGIN      
        1 ggtaagccga atttaatgtc caaactaaaa tcgagcgatt ttaacgttgg ttaccacggg
       61 tcactaactt cggataacga aaagctacat tttacttctg atggtacagg aagcattatt
      121 atgtttacgc gtattaatac acctcagctt gctagtggga aaacctatac tctgagtgcg
      181 aaagttcgat ttgatgaagg aactacagga gctattgata aattacgttt ggtgtatcgt
      241 acatcaccag gagaaaagat attattggaa gcaaatagta caaatattac aacagatgat
      301 gtagggaaag aaataacaat caaaggtaca gctaacgtta attatcaaat cacaaattta
      361 gatcgatttt atatgagtat tagctttgtt gacagggata aaataaatgg cggatttaag
      421 ttgtacgaca tcaaaatcga agaaggctca acagccacac cgtaccagcc taatctactt
      481 gatgcaccgt attatttgag taaggtggct ttgggtgaga atctaattaa accagaatca
      541 caacaaccag ttactaatag taactatctt attaacacct ataacattaa accaatggta
      601 aaaggtaaga agtataccat cacacttgaa ggaactaagc cagcaacaca ggtttttaga
      661 ccatttttca cacgagcaac aggagatgca tgggaggttg gtgacttaca accagtagaa
      721 gggttaactg atgtttggtc tggaacattt acagcagcag ctgacccaca ccctaccagc
      781 ccacaagttc agatttgtca ggtaccaagc acaagtttag gaaactgtac aattaaatgg
      841 ttaaaactag aggaaggcga cacacgaacc ccgaatattg agcaatataa ataccgagga
      901 atcggcatgc gagactcaaa caatccaaaa gattacgtct gggatctagc accagaatat
      961 gtcgaagaca atctggccac agatattaaa atttctgaaa ttactggtaa agcaaacaat
     1021 tataccgatg ggaaagtatc ggagattaat tcgcagttga ctgcttcaat taatgaagta
     1081 gacaccacag ctaaggatgc tcaaacaaaa gcgaatgcta atgcgactgc tatagatgaa
     1141 ttagacaata agatcgatga acgcattaat gatacagcta ctaccacatt aacagttaca
     1201 aacgggaata ccggatcagc aaagctttat cgtgaaggaa aaacagtttc tatatatttt
     1261 gtggctttaa acggaagaag cagtggtgga aatgattcaa cgatactaac aattccagaa
     1321 ggctatcggc caccaattag ttttgagcaa ctggttggct cgatagaccg ttctactttg
     1381 aacagtgctc agttatctat tggtgcagat ggagccatta aatggcgaag aaactcaagt
     1441 tatggatcgg attatacctt tgcaattact tacacgattt agaaaagcgt gaatcgatat
     1501 gaaggcagca tatagaccaa ttgaacctta cggattcgag caaatcattg tgaatgatga
     1561 agaacattta ccggaagaat gcacagaagt cgaaccaccg attccaaatt ggaaaccgaa
     1621 attcaattac tgggagggaa ataaatgaaa aacatttgga aatatggacg tactggcgga
     1681 gagtacgcag gaaaagtatt ggacgacatg cttgtatccg ttccttacac agatcagcca
     1741 ccgcttgaag gaattcgtgc tgatggcgaa ccgttaacaa tcgctgatca aatgtttgat
     1801 cctaaattga atcaatggat tattttagcg aacgcactag atcacaacga tttaaacaat
     1861 ctcaaagcaa tgtatgagtc gttagaaaat gagaacggcg atttaaaaca gatcaatgcc
     1921 aaactcatgc taagcgatgt agcaattaaa caggaaaata ctgcattgaa agaaaaagcg
     1981 gatagtttag cacaaatcaa ttcaaaaatg atgcttgctt cgttacaaaa tagcaaagac
     2041 atttcagaaa ttaaagagca actaaatcca gcttcaaagg gaggtgagta gtatgtttag
     2101 ttttagcgat gtgaaaatga tgtatgattg gggctgtttc actaacgaac aagtaatggt
     2161 tttcgttccg ttgtgcatta ctgaagaaaa agcagataaa atcattagca aagaagagag
     2221 cgcatcttaa ttgatgtgct ttttattttg attcaaggag ttgtcacatg attaatttag
     2281 gggaatgggg agcgatagca ggatcaataa ccgctatcgt ttctttgatt ttattagtaa
     2341 taaaaccaat tactgcatct ttctcgaaga ttactgagac tctttcaaaa gtaagtcaca
     2401 atttagattt gctgactaaa gatttagaat cgagcaaatc agatcgattg atgattcatg
     2461 aagaactaaa gaaacacgat gaaagattag atacacatgc agaaaaattg gtagaacaca
     2521 cgcaacaaat taaaacttta tttagggaga gaagaaaatg aataataaaa cgttcgaagt
     2581 actaaaatgg ttcgcactgg taattattcc cgcactagct actttcgtgg ggttagttgg
     2641 taaagcgctc aattggcagt acacagatat ctgtgttgtc atcattactg gttttggcgc
     2701 gtttttaggg agtgtgttgg gtgtatcaaa tcgaacctac aaaatgttct cggctgaaag
     2761 cgaagaagga ggaaacaaat gaaaaagaaa attactatta ctgcgatgag cctgttaacg
     2821 gctctttttt tattacccat taatacgttt gcttatacta ttaatgacga gtataattta
     2881 gcgccgaatc aaggagactc cagattagca attcctaaca aaattatttt gcacgaaact
     2941 ggaatagatg caccagcaag aaacgtagcc gccaacatga aaaataatta taacggaagc
     3001 aattcttata ctacagatgt tattggtgac ggtgggattg tttaccgtgt gggtgagcaa
     3061 ggatatgttt cgtggggagc tggtaacgct aatccttatg cgcctgtaca gattgaatta
     3121 cagcgcacat atgataaagc attgtttgaa aaaaactatc gagcttatat tgaatataca
     3181 agagatagtg caaaaaaata tggaattcca ttgactcttg atcaaggaac ttctttattt
     3241 acaaaaggaa tcatttctca tttgtgggtg acaaattatg tttgggggaa ccacacagat
     3301 ccatatggtt acttatcgca aatgggagtt agcaaagaaa agcttgctta tgatttagct
     3361 catggattta ccgatgaaaa tccaacaact tctgaaaaca agcctgtcat tgatccaaca
     3421 cgagctggtg cagctaatcc tacgctgaca gatggaacaa atcacgccca cattgatcag
     3481 tttggggaaa tcgaaaacgc aaacttgcat gtggctggat ggcacattgc taactataaa
     3541 tacgagtata ttttcattat ggactacaat actgggaaag aattagctcg agtaagagct
     3601 gatggaattt atagaccaga tgtaaaccaa gcttataata cttctggaaa tgttggttat
     3661 catgtatctt tcaatatgcg taattttcct agtaagaaag tctatgtaat gatgcgggca
     3721 acgaatgatc cagagggaaa cactaaaggc ggtgcgcaag atttccatga caaacgttgg
     3781 tatttaaata ttcctaaacg ataaaaatag ctcctcgttg aggagcagta cataactata
     3841 ttgacaacta taaaaattat tcgataaaat agtgatgtta tcgcatatct tcactatcac
     3901 ccat
//
LOCUS       DACGDM010000158         3713 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.166, whole genome shotgun sequence.
ACCESSION   DACGDM010000158 DACGDM010000000
VERSION     DACGDM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.166"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="IXR05_002794"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="IXR05_002794"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAQ4261232.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="IXR05_002795"
     CDS             complement(2261..2512)
                     /locus_tag="IXR05_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAQ4261233.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="IXR05_002796"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="IXR05_002796"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAQ4261234.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="IXR05_002797"
     CDS             3462..3680
                     /locus_tag="IXR05_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261235.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
BASE COUNT         1025 a          797 c          688 g         1203 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aag
//
LOCUS       DACGDM010000159         3680 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.167, whole genome shotgun sequence.
ACCESSION   DACGDM010000159 DACGDM010000000
VERSION     DACGDM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.167"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            75..470
                     /locus_tag="IXR05_002798"
                     /pseudo
     CDS             75..470
                     /locus_tag="IXR05_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            790..1104
                     /locus_tag="IXR05_002799"
     CDS             790..1104
                     /locus_tag="IXR05_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261236.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1208..2386
                     /locus_tag="IXR05_002800"
     CDS             1208..2386
                     /locus_tag="IXR05_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4261237.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            2789..3082
                     /locus_tag="IXR05_002801"
     CDS             2789..3082
                     /locus_tag="IXR05_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAQ4261238.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1256 a          542 c          715 g         1167 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga tttccatatt
      481 tcgattttgg ttggcatatt tttcatgcca aattctgtga ttttaatagc atcggcaaga
      541 tttaattttt cttcagctct ctctccactt ttaagttttt ttactgtact caagttgatt
      601 cctgttccga atgctattgc attagccgta gatttttcaa gaatttcttt aattattttt
      661 atgtctgcaa ttccttgttt catattaaaa attcctcttt tctagtccgt tttgatggag
      721 tactggagtg tttttttaca attttaaggg gtaccgtggt ggtcgttttg attttgagag
      781 agaagggtga tggagttgga agttaaaaca aatgttaatt ctctggaaat agagttctat
      841 tcaattttac aaaaaaaact ggaagattac acggaaaaat tgcttgcagt cagtcattta
      901 cctctggtat taacaaatac tgatttaaag cgactatttc agataagtga tagtacactg
      961 aaccgtttag taaaacttgg tgagtttcct ccctgttggt acgggattcg aggacactat
     1021 tttcgtgatg atgttttaga atggatgaga aagagtgatt cgaatgacta tcgagaaaaa
     1081 ttgcgactac ttcgatcttt ataagttaca ttttctttct aagatgcggt acaatgatga
     1141 catagataga aagatttcca aagggtttct gcttgttggg ttccttcaaa ataggaggaa
     1201 tcaataaatg gaaaaaacag atcgattcaa gaagcaaatc agttctactg gtaggatcac
     1261 atggtacttt caagcatatc gaacaacaag acgtggcttt aattcaaaac gtgaggcgca
     1321 actcgcttat ctggaaatgg agaaacaaca aaggcttaag aaaaaaattg ttgcaagcaa
     1381 tgacaagttt agtgttgtag gtgagcaatg gttccaatat taccgttcgt taaatgaaca
     1441 aaaggaaata acctatgata agcgagagga acaattaaaa attattgttc gatggattgg
     1501 tgataaaaag ttgtctgatt tgacaccaga gtgccttcaa gaattgcttt ttaccttaaa
     1561 ggaatgtggc gttaatggaa caaatgttgg ctatgccaaa aatagtttac aatcacttat
     1621 tcaagttcta aatatgattt ttaaatattg tcaaagaaag aatttgataa gtgaaaatcc
     1681 aatgaagtct gtgagaatgc caaaatatca gttaacggta actgatttaa aagaagccat
     1741 aaataatatt gaggacaagt ttcttactgt cgatgaattg agaacttttt tgaattatgg
     1801 cattgttcat gaggaattac cgatgtctgt acttttccat gttctatttt acactggctg
     1861 ccgagtcagc gaggcgcttg ctctacagcc tggagatata gatttcaaaa gaaatgaaat
     1921 tctgttctat aagcaaacgg cagttaaagg taagagtaag gattttcgaa ttgaaactac
     1981 taagacagtt agttctgcta gacgagttct agtaactcct ctagttatgg aaaagctaca
     2041 acagttgatt aaggctttgg gtgagatgag gcaacattac aggtttatta tagaagaaac
     2101 atatttgttt gtgtatcttg attctagtaa acgtggtgtt ccttatcgtc gagagtatgt
     2161 aaatgatcac gtcaaacggt gcgtgaatcg ctcaggaatt aataagccat ttcatactca
     2221 tttagctcgt catacaatgg caagcttagt agcggaacac tgtagctggg aagtcttgaa
     2281 agatcgctta ggccatactg accaaacaac ttcgaaaatt tatcgccact taacgtcaaa
     2341 tgaaaaggta aaacctctga ttgcttttag ttctttagag agttaaaaaa acggtgaaag
     2401 cactggtatt acaggattct tgaaaaacga ttttttaaca aattagtcaa tatgtagtca
     2461 gaggtaataa aaatcctttt atatcaatac tttaacgact tttcacaagt atcaaagaaa
     2521 tccgtcgtta atcattgtta tcagactgag aaagaaccct tggtattcaa gggttctttt
     2581 ttcttagcat gtaatttgaa caccctgatc cagttttttc tttaattatt ggtaggggag
     2641 aataatggat tagaataaat ctacctataa gtagtagtaa aaaaaagagc actatgataa
     2701 tatctttctt aagagtaacc gctttaataa aaaatccaga atattctaac ataaatggag
     2761 tattcttaga atcaaaagga gaaagaagat ggtttatact tatacggagc aagaaaagat
     2821 gaaagtttta gacacattca tgaatgatgg aaaagtaaaa caagtaccaa gttcaacaaa
     2881 aaagaaatac atcctattga aagaagtctt gaaacgcttt gaccatggag tgacttatac
     2941 agaaacagag gttaattcga tactgctgaa cgtattttct agtggcgatt atgtcgaaca
     3001 aagacgttat ctaatcacat ttggcttttt caaaagaagt tcagacggtc gggcatatca
     3061 gatgatggga attgaaaatt agaagtttta atttatactc attgaaaaaa gttcaagtat
     3121 gcgatattgg ttctacaccg catacttgaa ctttttttgt catctgtatc tataatacaa
     3181 agccaagaac gttattcaaa atatggatag ctatgataaa agctaatgag cgattcgcag
     3241 ttaaataagc aatcgtcagt aaaatcgttc caggagcgta catgaaaaaa tcaattggat
     3301 gcgttacatg aataaagata attctctttt atttgtacga ataaatacca aaacgtacct
     3361 cctaaaatta gattttggac agatgccctt taaaaagata acaagatttc gttcttgaaa
     3421 caatatatat gcttttattc caatgaggtt gtgaaaacag tattttgtcc tgagcgttag
     3481 aaaattgaaa atggggaata gcaactcgta ctttaccatt ttttaagtga atacaagatc
     3541 agctaattga acaccgttta ttcgtgatga gggacacaac actgcagtcg acacatttct
     3601 cttttatgtt caaagataac aaatatttaa aacaaagaaa aatagtagat aatcccgtcc
     3661 taactctttt attcttccct
//
LOCUS       DACGDM010000160         3566 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.168, whole genome shotgun sequence.
ACCESSION   DACGDM010000160 DACGDM010000000
VERSION     DACGDM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.168"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            74..1048
                     /locus_tag="IXR05_002802"
     CDS             74..1048
                     /locus_tag="IXR05_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4261239.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1030..1491
                     /locus_tag="IXR05_002803"
     CDS             1030..1491
                     /locus_tag="IXR05_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4261240.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1541..2005
                     /locus_tag="IXR05_002804"
     CDS             1541..2005
                     /locus_tag="IXR05_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4261241.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2019..2768
                     /locus_tag="IXR05_002805"
     CDS             2019..2768
                     /locus_tag="IXR05_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4261242.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2768..>3566
                     /locus_tag="IXR05_002806"
     CDS             2768..>3566
                     /locus_tag="IXR05_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4261243.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILA"
BASE COUNT         1196 a          481 c          692 g         1197 t
ORIGIN      
        1 agcaatttca tagataatag gtattgtaaa gttatatgac tttataatac ttattagagt
       61 gagggataaa gaaatgagac aactacacaa agaacagatt gaaacagcaa tggcagcgtt
      121 aaaggaaaag acaattgatc atgtatattt tacagcatgt gggggttcac aagccgtttt
      181 aatggctggt caatatctat ttgataaaga attaactgta ccttgtcatg tttatactgc
      241 taacgaattt aactatgcta taccaaaagg attatctgaa aattctttag ttatcacttg
      301 ttcccattct ggcacaacac cagaaactgt agaagcaaca aaaaaagcaa gagaatttgg
      361 agcaatgact atttgtttat ctaatgaaga aggatctcct ctatgggaag cagctgaata
      421 tcctgttcac tatgattggg gtaaagatgt tgatgctagt gatttaaata aaggaattct
      481 ttatggttta ttatttaata ttttacttgt tttagatggc tctaaaaaat gggaaacttg
      541 cttgaatgaa tttgataagt taaatgatct tgttattgct gaaaagagca aatttgaaat
      601 aactgctaaa gaatggggta aaaaccaaaa acgagataaa attatttaca caattggtag
      661 cggtatcaat tacggagaaa tttactccac agcagcttgc tggttcatgg aaatgcaatg
      721 gattaattct aatgctattc attctgggga atttttccat ggtccttttg aaatcactga
      781 ttatgatgta ccattcatct tagtgaaaag tattggagat acaagatttt tagatcaacg
      841 ggtagaagac ttcactaaaa aattcagtaa taaattaatg gttttagacc aagctgattt
      901 tgacttagaa tctatagata gtgtagcgaa agaatatatt gcagctgtac ttagtggcgt
      961 tgttattcgc caaatggtag aagcgattgc ttttgaaaga ggccattcct tagatgttag
     1021 acgctatatg tggcaaatga aatattaatt aataggaggt tgcaaaagat ggcaaatcaa
     1081 ttatttcaca ttgtgattac aacacattct accctttgtg agggttattt aaaggcaaca
     1141 aaattaattt taatgaatga cgccacaggt attagtgctg ttccatttaa agaaaatact
     1201 agtccagatg attttgagga gagtatgaaa gaaataatta gtcagcatca tttgcaacct
     1261 ctaattattt taacggattt aattggagga acacctaata atgtttctat taaacagttg
     1321 aacaacaata gaattcaaat tattgctggg attaatttac ctcttttact ggagttatta
     1381 atggcccagt cagctggtaa atctatagaa gaaatagatt ttaaggaatt actgaataac
     1441 tctcaaaaaa gtatggttca tattaattcg cttttaaaag atgtcagtta aggtggcaat
     1501 ttctattcta taaattttaa aaattgaagg aggaaataga atgattaaat tagtgcgtgt
     1561 agaccacaga ttacttcatg gacaagtaat attttcttgg actaaacagt atgatattaa
     1621 ccatattatt gtggctgata acaaagttcc aggagatcca atgtctgtga tggctttgac
     1681 aattgctaaa cctgctgatt gcaaattaga cattgttaaa attagtgatg ttaaagggat
     1741 tatggaaaca tccccaaatg ataattacat gattttaatt aaaggaccta aggaagcttt
     1801 tgaattagtt caaaatttac cagaaattaa agaaattaat tttggcggtg tgtctaagaa
     1861 aagcgagtcc aaacaatatg gaaaggcagt ctttttaact cctgaagaat tagaagccac
     1921 aaaaaaaatt cttgatcaag aagtgaaaat atttgtgcaa caagtcccat cttcaagtat
     1981 tgaaaatgta gattttagta agtaaggggg gaaaataaat gttattaaaa gccattttat
     2041 taggtttagt tggtgtggta gctgttattg actccaggtt aattggtcga caaaatattg
     2101 gtagaccact aattttgagt acacttgccg gacttgtgct aggtgacttg catacaggga
     2161 ttgttcttgg ggcatcttta gaattaattt ctatgggatt cgtctcaatt ggggcggctg
     2221 gacctcctaa tatgcaactt ggtagtatta ttgccactgc ttttgcaatt ttaactaata
     2281 gtagtacaga aacagcctta acaatagcta tcccagtggc tgtagctggt gaatttatga
     2341 gtattatcat gcgcatgata attgctcaat ttggacatgc tgcagataaa gccattgaaa
     2401 ataataaatt tagaaaagct caaattattc atatttattg gtcatttatt tttaatgctt
     2461 ttgtttactt tattccaatc tttttaacag tatattttgg tgctgacgtt gtggcagatt
     2521 tagtagataa aattccagaa atgattacag acgccttgac tgtctctgga aatatgcttt
     2581 ccgcattagg gtttgcaatg ctattaagca caatgttgag taaaaaatta tatccttact
     2641 ttatttttgg attctttatt gttgcctatt caggtctttc actaattggc gtgacaattt
     2701 ttgcagctct gattgccttt gtaatggatc aagttaaata tggaaaaaga gaagaggcgc
     2761 atggttaatg gaaaatagta cagaaaaaaa acgtttaatc acaaaaaaag atcttaataa
     2821 gatgtgtctt cgttcatgga caatcatgtg ttcgtggaat tatgaaagac aaatgcatat
     2881 gggatttatg tatgggatgg cgccaatttt aaataaagtt tataaaaatg atgaagagaa
     2941 aaaaagagaa gcttatactc gtcatatggc attttttaac tgtacgcctc aaatgacttc
     3001 atttattatg ggactttgtg cttctatgga agaacaaaat gctcaagcag aagaaggaaa
     3061 ctttaatact gaatctatct ccatgattaa aaccagttta atgggtcctt ttgctggaat
     3121 tggtgattca tttttccaag gtactttaag aattattaca tttgggattg gattgtcttt
     3181 tgctaagcaa ggtagtattt taggaccgat tttagctgtt ggcctttttg ctataccttc
     3241 tattttagct gttttttacg gcggtaaatt aggatatgag tctggcaata aataccttac
     3301 taaattgtat caagaaggtc ttatggatcg agtaatgcaa tttgcttcta tcattggttt
     3361 ggctgtagta ggtggaatgg tggctagcat ggtgccaatt gtcacccctt taaaattcac
     3421 tacaggggga acagaacttg ttttacaaga cttacttgat tccattattc ctggattatt
     3481 accacttgta tgtactttgg gaatatataa attgattaag aaaaatgtta gtacaaatat
     3541 gctcttatta ggttgtattt tggcag
//
LOCUS       DACGDM010000161         3480 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.169, whole genome shotgun sequence.
ACCESSION   DACGDM010000161 DACGDM010000000
VERSION     DACGDM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.169"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            147..380
                     /locus_tag="IXR05_002807"
     CDS             147..380
                     /locus_tag="IXR05_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAQ4261244.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            377..784
                     /locus_tag="IXR05_002808"
     CDS             377..784
                     /locus_tag="IXR05_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAQ4261245.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(1921..2439)
                     /locus_tag="IXR05_002809"
     CDS             complement(1921..2439)
                     /locus_tag="IXR05_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAQ4261246.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1181 a          590 c          525 g         1184 t
ORIGIN      
        1 gagcaatcta aattttttga attttcttaa ttaattatat agaaagaaca atctttctat
       61 agagttagac atgagaggga ctatgcttga tttaaaatca acaagcgtat atactgtata
      121 tacaaagaaa aaggagggag aagactatgg caattaaaga aagaaaattt agggaagtgg
      181 ggaactcagt agtattaact atttcaaagg agtttcttaa agaaaatggg ttaaatcccg
      241 gagatacggt ttttttagat gaagaaaaac ttcgagcggc aattacaaaa aaacaagcct
      301 tatctgatga aattgattta gcaatatctc aagcattaac tgaatatgat actactttta
      361 gagagcttgt cgataaatga gtattcatta cctagaagcc aaagatatta taaaaatgaa
      421 tgtaatccaa ataaaaaaat actctcctaa tgaacccctt ggtgtaaagg atgcgaatgc
      481 tttagaaatg tgtgtagggc aacttcgagc ctcagctttt ggtgaagagg tttatccttc
      541 gatttatgaa aaagcagcta tcctacttat acaattgata aagaaacatc cttttcacaa
      601 tgcaaataaa cgtactgctt tcttagctac ttttgtcttt ttgaaaatca atggacagct
      661 tttagctatt gatcaaaaag atgctgtaaa tttagcggta tatattgcta cgtatgataa
      721 ggatttcgat caactaaaat atgaagtgat caacactata aagacacata cgcagcccat
      781 ttaaggagtt actgtatgtg tctttatagg gttattagct gctatagcga aataattgaa
      841 gtaaattaca aatagctata attcaaatcc aactatatag aaaacgtaaa ttttctatat
      901 agttggatta agataacgac tatttatttt atcatatttt tactataccc tatactttta
      961 cttggtatat ttatgaataa tcgcaaattt acccctatac tactagtttg taagttagat
     1021 taataaaaat actaaagtta tttgttcttt tattaaatac acctacaact tataaattga
     1081 tggtatttag ataacacgaa agaataaaaa taacagctga tagtaaagtt tgttgacgat
     1141 tgctactcaa tcgaaagtga gttagtgcgt atgaacttgc ttctgaaaac ttatgaaatg
     1201 aaagaccttt tacatcttgc agaaatcggt actgggatta aactaagcaa taaaaactaa
     1261 tgttcccctc attctttgaa cttctactat ttgatttatt tattctgata aatgacgatt
     1321 tcaccttcag gatcttcaaa tcccgtatag aatttattta agatctcttc agtatcagta
     1381 ataggatagg cgataggcca catacccttt gatggttaga ataaactgct caaaatctgt
     1441 atcgtatgtt ggctttagca tattaacaaa ggctatctcc aaattataaa ccataagcgt
     1501 tgaatcgttc ttaacaattt caattcttcc taacccaaag tcagaagata taattaccgg
     1561 acttgcctta cccttcatgt gggttgttga gattccatat ttaaagggaa ttgtcggtac
     1621 tatcggcggt ctgaaaaaca tcccaaaaat aaaaaaatct ttcccctgct agtctcctaa
     1681 gtccctttgt agcggatatg gcaccataat ctcattttat cgaagtgagt catggtttat
     1741 ctgttggcca accaaaattg atacaatcta acgatgcacc ctctacggca ttctagggga
     1801 gtgcacttgc attcacccaa taaaaaccgg cagttagcaa agaacttatg tagtcgtatg
     1861 ttcttactgt taacatacaa gaggtctcct ttccacaatt gcttagcagt aaacgggaat
     1921 ttacaaagct aatctcttcc attttcttat ctttgttcta aaagtcccaa atggagcaac
     1981 tgtatttaca tgaataaatt tatatacttc ccatacagcc gttttggttg cctcgtctgc
     2041 ccattttctt ttgtgtgcag tgaatagatc ttcatcactc attgaatcaa tcatcatgtt
     2101 aatatcatca atattacgat tgagaatttc ctctaattct ttcaatggta gatgtgcata
     2161 ggtatttgta aaccacttat ataactctcc taactgattc catttaaatt gatcagaagg
     2221 cgttttaaca gataatccat ttctttcatc attttcccat tttagaatta aattcgtcca
     2281 accaacttga tatgctaaat tttcagcagg tgttctatcc acttcctcaa ctcttttatc
     2341 cttcaattct tcaggaatag tttcaaattc taaaatatat ttagtataag tcctatttat
     2401 ttcttttttt aattcttctt tatttttata tgttctcatt atattacctc cataaattcc
     2461 taattgtctc ctttaattca tctataattt catccacgat attttaatcc gttctacaat
     2521 gcatatctga tatgcattga ctgtctaact catatgtgaa tgatttataa aatatcccaa
     2581 cgtctcatct aaagaaatgt tgatcgtcag caaggagcta aaaaatacga atatatttct
     2641 tttgtagtaa aatcggactg gtttgcatat cattttcttc gtaaatatca aaatcatgtt
     2701 aactactatc aattactaat aaaaactacc actttaagcg ttaagaactg ttaagtttag
     2761 ttaagtgagg atagttcaca aaatccattg ttaaacttca cgaaagtggt aaaactcaaa
     2821 atgctttata taggattaca gcatcgctct ttcttcgatt gcgcgttggg taaaaaatat
     2881 tatgaagtaa aaattgacga tgacacgttc cttacggctc atcagatgaa acagctacaa
     2941 aaacgaaatg atcaactcga agaaaattta attctaaaaa agcgattgcc atattcacgc
     3001 ctcgctcgac gaactattaa aggtcaagat ttacctgaag atcatccttt ttaggaaatt
     3061 gaagcttttt atgttgcaca atgcatttat aatactacaa tgatgttttc accagatatt
     3121 cttctagggt gcggtgtaat gaaacagata cacttgcaaa agaaaattca ccgcgaattt
     3181 actaaaatta tgaataatta tgttaatctt ccgaaatttt tttccaaaat taagggatca
     3241 agctggtgtt atagattgtt taaggttggc aaaaaaataa cttcttttta aacaattata
     3301 gaaaaccgat actctgttaa gttggttgac acggtgtcga tttttatgac tttcttattc
     3361 tgaaacttca ctaacggaca gtacctaaaa agtctatagt atggacgttt acgagtacta
     3421 ttttatcaaa aatgctgctc atttcaactt atatgtttta gtgaactacc cccacttagc
//
LOCUS       DACGDM010000162         3448 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.170, whole genome shotgun sequence.
ACCESSION   DACGDM010000162 DACGDM010000000
VERSION     DACGDM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.170"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..2232)
                     /locus_tag="IXR05_002810"
     CDS             complement(<1..2232)
                     /locus_tag="IXR05_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261247.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="IXR05_002811"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="IXR05_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          965 a          763 c          547 g         1173 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg aatccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacact tttataaaac gacgaaaa
//
LOCUS       DACGDM010000163         3406 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.171, whole genome shotgun sequence.
ACCESSION   DACGDM010000163 DACGDM010000000
VERSION     DACGDM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.171"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..804
                     /locus_tag="IXR05_002812"
     CDS             <1..804
                     /locus_tag="IXR05_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4261248.1"
                     /translation="LIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNTKVGDA
                     TIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYSTIRLLD
                     EEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQAQVASL
                     LTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQTAIEE
                     FLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1034..1264
                     /locus_tag="IXR05_002813"
     CDS             1034..1264
                     /locus_tag="IXR05_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAQ4261249.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(1487..1585)
                     /locus_tag="IXR05_002814"
                     /pseudo
     CDS             complement(1487..1585)
                     /locus_tag="IXR05_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1850..2305)
                     /gene="tnpA"
                     /locus_tag="IXR05_002815"
     CDS             complement(1850..2305)
                     /gene="tnpA"
                     /locus_tag="IXR05_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAQ4261250.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKIFRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2548..3406
                     /locus_tag="IXR05_002816"
                     /pseudo
     CDS             2548..3406
                     /locus_tag="IXR05_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         1130 a          585 c          591 g         1100 t
ORIGIN      
        1 ttaattaaag aaaattatcc atttttaacg aagtctgaaa aaaaagtcgc tgattttatt
       61 ttaaattctg ggaaaactat tatttatagt acgatgagtg atattaagaa aaacacaaaa
      121 gttggcgatg ctactattat tcgcttttgt caaaaaattg gtttttctgg tttttctgat
      181 ttaaaaattg aaattgcaaa ggaagacttt agtcaaaaaa aagaacatcc gactagtgta
      241 aagtactatg atgaaattgc taatagttta acagaagctc tctattccac tattaggctt
      301 ttagacgaag aaaaattgaa tgaagccatt aaaatgatca ctcaatcaaa aaacatatat
      361 atatttggag tgggatctag tggaaatact agtcttgatt tagaaaatat gtttcttcgc
      421 gtaggagttc aagcaaaagc tgtactagac cctcattttc aagcccaagt cgcttcttta
      481 ttaacagtta atgatttagt aatcattttt tctttatctg ggaaaacgaa agatacttat
      541 gattcattga aaatagctaa aaaaaatggc gcaaaaatta ttgctataac taactatatt
      601 cattcaccta taggaaagtc tgcagactta gttttacaaa cagccattga agaatttctt
      661 aatggtggat ctttagctgg aaaaatatca caactttata tttgtgatct attagttcat
      721 ggttatgaac aaaacaataa tattgattca gttgaattaa gagaaaaagt tttgcgctct
      781 attattgata aaagtattga gtgaactacc cccacttagc taaacctaac ggtttttaac
      841 gattgaagta ggcaattctt gggatgagag catacttgat agcttatttt ttactaatag
      901 cggtggctct tattgaccaa atatccctgt agttcctacg gttcttgatt ttatctaaag
      961 atatttttat cgtggaagct attgatcaac ttgaaagaaa aacgtgtagc tcattatcac
     1021 tagtttatcg agtatggatg aagcaatgga tcatcctctc ttaaataaat ttattaagga
     1081 tctgatcctt caaatttttt ccatgatcga tgagcaggaa cctactgaat ctaaacgaca
     1141 tcgggcacaa ggaattatta agattgctaa gcgaatgttt tctataaagg gtgttctaag
     1201 ctatacagtg ttaattcaaa agattcccaa tcatcttgtt tataagaaca acgttgaaga
     1261 ttaaaaaagt gtttcaatgc taaaattgca aaatacttca atgttatgag acaaactgtc
     1321 tataagaatc aatttccacc catttcatca cttgttaaaa gtttatgatc cttttgattt
     1381 ttatattaat ttatctgtat ttaatacaga ttttatttat tagttcatct gcctattgta
     1441 ttttattttg ttgccttacc atctgaagta aatatactct taattgtcaa attaagttag
     1501 acagatcatc aatacttacg taactcaaaa atacttccaa aggtgttcga taatccagtg
     1561 attttctagg aagattattt ctgcgccagc attttctaat gtttgaattt gtgttttgta
     1621 atcttggttg cttgtgctaa ttcttgaata gccgtaaatt gccaaaattt catcaccctt
     1681 tctggacata agtttctgac accagttaaa atcaagtcta tcagtaaccc atacacccgt
     1741 gaggacgggt gtatttttaa tccccctaga aggggtcgac actcgctgcc ccttaaaagg
     1801 ggatttttaa aagaccgcca actgctcatc ttcactcact tacttctctt tattttttaa
     1861 atggttctac gtactctctt ttacttataa tatatcgaat gcgatcatca gcttcttgtt
     1921 cacggatgta tttttcattt gtcttttgat tcaatccgac tgtactcaca tagtatctct
     1981 tcgaccaaaa ggatttgttt ccgtatttat atttgagatt tgcgtgctgc tcgtggatta
     2041 gtaccgcact acgacctttc agatacccca taaaactgga tatacatatt tttggtggta
     2101 ctcgaacaag catgtgaata tgatctagca ttgcatgtgc ttctatgatt tccacatctt
     2161 tcatttcgca caacttccta aatatttttc caagatcttt tcgtaattgc ccatagatta
     2221 cttttcgttg atattttggt gtaaaaataa tatgatactt acaattccaa cgagtatatg
     2281 ctaaactttt atcgtcattt gacatgaaaa aactcctttc gatctgatga gcggttggta
     2341 gccactcact agtatatcga aaggagtttt tatcgctaaa gatacttctt ccacgcgtag
     2401 aaacgcgcgg ttttcttgtt tcgcacgctt tacgcacaaa actgactgaa gtcattaaga
     2461 aaataaaagg gtctaaaact tttaagtttt gtaccgaccc ccaaaagtta gaccaaaaaa
     2521 tctaactttt ggaggtcggt gttttttatg gctaagtata cttttgaact taaattaaag
     2581 atcgttcatg attacttgga tggtaaaggc ggaagtgatt atctggcaaa gaaatattcc
     2641 attaaggctc catcacaagt gaagcgctgg atcaatgcct atcaagaatt tggtgaagag
     2701 ggtctagtaa gaaagcgaca aaagaaaaaa tattctgttc aatttaagct ggatgcgata
     2761 gagttatatc taacaagtga gctgtcctat cgtgaagttg ccaacacact taacatgaac
     2821 aaccctaatt tgatcgctag ttggatgcgt caattccgtg agggtgggat cgatggactc
     2881 tcaaaaacga aaggatgtcc acctatcttg tctaagaaaa atgaacccaa aaataagaaa
     2941 aaatctacaa ctaaagcaac gtctaaagaa cgtgaacgca tcgaggagtt ggagaaacga
     3001 gtccgttccc ttcaaattga aaatgccttt ttaaaagaat tgaggaagct gcgaaaacag
     3061 gaagcccaac aacgacgaat gaagcaatcg cacgaatcat cgcaagcctc cgaggaccgt
     3121 ttaaattagt tgagcttcta gaaactttaa agttccctaa ggcaatcttt atgtactggc
     3181 aaaaacgatt ggaccgtaaa aatccagatc aagagattga agcggaaatg cttaaagttc
     3241 gggagaagca caaggattat ggctgtttac ggatgaccaa tgaactaaga aaccgcggtt
     3301 tctctatcaa taaaaagaaa gttcagcgcc tgatcaagaa gctaggaata aaagtaacga
     3361 catacacacg taaatcacgg cgctacaatt cttatcgagg acaagt
//
LOCUS       DACGDM010000164         3391 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.172, whole genome shotgun sequence.
ACCESSION   DACGDM010000164 DACGDM010000000
VERSION     DACGDM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.172"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(22..2493)
                     /locus_tag="IXR05_002817"
     CDS             complement(22..2493)
                     /locus_tag="IXR05_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4261251.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            2766..>3391
                     /locus_tag="IXR05_002818"
     CDS             2766..>3391
                     /locus_tag="IXR05_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4261252.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPR"
BASE COUNT          999 a          686 c          609 g         1097 t
ORIGIN      
        1 tcttttttga gatacttttc gtcaattttc tcgtttaaat atcgatagaa attttttagc
       61 tacgcgacta aacggctttt gctctttttc atttttacgt tcaaacaaat attctaccaa
      121 tgtggtcaaa tgcctaaaaa tcgaatctgc cgagaaaaat agaatgctca acagcaaaag
      181 tgatacagct gagataccgg tgattgaaaa cagcttatgc aaaaagatga ccgaaaaaaa
      241 gttaccgcta gcacagaaaa gaatgatctg acttctgaat ttattcagcg gtgaacagat
      301 tttatagaga acgaggaacc ctactgcaat caaaagcatg gtagatgctg tagaaacatc
      361 tgttttattt agattcaaag tcaccccgca gatcaccaac gcaccgacta cgatcatatc
      421 tgttagtcca cctggcacag ctttttccat cacattcatg atgaatttcc ctctgattcg
      481 ctttttgttt tcttctagag caagcaagaa agatggaagt ccgatagtaa acaaactaat
      541 caatgtgatt tgtgatggtt ctaaaggata ggtcagagca aagatcactg aaaacagtga
      601 gagcaaaaag gagaaaatat tcttcactaa aaacaagctg gctgatcgct caatattgtt
      661 cacaacgcgc cgtccttctg caacaacttc tggcatgcgt gaaaagtcag aatcaagtaa
      721 gaccacttgt gaggcctgca tggcggcttc atttccggaa gccatcgcta tactgcagtc
      781 tgcttctttc atggctagaa tatcattcac gccatcacct gtcatagcta ctgtattgtt
      841 acgctttatc aattgaacga agattttctt ttgttctggc ttgacgcgtc caaaaactgt
      901 atatttttcg acagctgctt catattcttc ttctgataat ttagatgcat caacgtactg
      961 atcagcatgt gaaatccctg cttggacagc tacattggat acggtgagcg gattatctcc
     1021 agaaatcact ttgatggcta cttgctgttt tttgaagtaa tcaaatgtgg ctcttgcttc
     1081 ttttctgata ggattagcaa tcagaatata gcctaatggt gtgactgctt ctgtcaatac
     1141 tggttcttca agaatcccat cgtacacacc aaagaccaac acgcgatagc ctttttcagc
     1201 gaaagaaaca aactcttccg catattccgg caattgatcg cgcaaaacca tttcgggcgc
     1261 tcctaaaaca tacaccttgt ctgccaacgc tacactgctg aatttttgga cagaagaaaa
     1321 aggaataaca tggtgatagg attgatcagt ggtttttgta aaatatgctt taacagcttc
     1381 cattgttgca ttgtctcctg ccatcgcttt tgcatagtca gcaatgcatg cttccaattg
     1441 atctgactga ctgattattt cttgtttttt agagacgatc attttttgaa cagacatttt
     1501 attttctgtg atcgttcctg ttttatctac acaaaggaca tttacccttg ccaatgtctc
     1561 aatgcttttc atattgtgta aaagaactct ttgctttgct agtttagtcg cacttaatgc
     1621 taatgcaatc gtcgtcagca agtacagtcc ttcaggtatc ataccgatca atgctgcttc
     1681 cattgcaacg acactttctt tgatcgtgtt tccattaaaa aagtaacttt gagaaaaaag
     1741 caggataccg ataggaataa tgatgatccc aatccatttg atcaattgat taagagaagc
     1801 aatcatctcc gactgttctc cttctcccat tgtcttggct ttgactgtca gctgggaaat
     1861 atacgaatct gctccaactt tgtctaatcg ggcgtaagct tttccggaaa caatgaaact
     1921 gccggacatt aatggatcac ctatttcttt ggttatttca tctgcttcgc ctgtcaataa
     1981 agcctcatta acttgcagtt tcccttccac gacctctgca tctgctggaa tttgatatcc
     2041 agtctctaaa ataacaatgt catctattac aaggtcttct atatctattg tttgttctat
     2101 cccgtctcgt atgacattga cttttgctgt atttaaaaca tttagttcgt ccaagatctt
     2161 tttggatcga atttcctgaa aaatggcgat tcctgtattg gctatgataa ctggtaaaaa
     2221 agtcaagttc ttataggatt ctactaaaca aagcaaaatg gctaagataa gaaagatcaa
     2281 attgaaatac gtaaatatgt tttccaatac gatttgctga tttgttttga atgtgggatc
     2341 gactgaatta tttgctgcac ctttttctat tcgttccttg acttgatctg ccgttaatcc
     2401 ttctttatac gatggaaaaa gacggatgac tttatctgat gatctttgtg ttactttctt
     2461 ttttttactt cgatttatcc atttattctt catgtggcta cctcgattga tttcgttttc
     2521 tggatatttc caaacttctc ctatccagta tagaacagat atggaaagtg ttcctcacat
     2581 taagcttgca aacacctttc attcctgtca tatagcaaaa aaaaagggtt ctataatatt
     2641 ttgtgttggt ggaaaatcga aggcgatttt ctactaacac tttttcttcg tttcaactca
     2701 aaaagagact cacttttggt aaaatttagt cgaccaaaac gtcatcctac caaaggagtc
     2761 tctcaatgga taatcatact agaaaattac tcggattaac agataaacat ttattttttg
     2821 atgaagaatg gctgattgaa aaagaatata aaggcgttca agcgcagttt attaaaggaa
     2881 aattggatga ctcttcttcc tattgtgaac actgtcgatc ggttcgtatt atccgcaacg
     2941 gttcctatac gacacgcact cagatgttga aagtcaaaga aaagttaact attttagaat
     3001 taaaacgtac ccgttttctc tgccatgatt gtggaaggac cttttctgcg aaaacggact
     3061 tagttgatga acatcatcaa ctaacaaagg aactgaagca ggtgattctc atggaactgt
     3121 acgaaaatca atcacgtaaa ctaatcgcta agaagtactt cgtctcggat gggacggtga
     3181 cacggatctt gcgtgaagca acgaagcatt accagccacg tatgaacttc cttccgacgg
     3241 tgttgtgtat ggatgagttc aaatcaatga attctgtttc tggttccatg agttttattt
     3301 gtgttgatgg gacaaccaat cagctattta cgatccttga agatcgcaga ctttacaaac
     3361 taactcaata cttcctgcgc tttcctagaa a
//
LOCUS       DACGDM010000165         3380 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.173, whole genome shotgun sequence.
ACCESSION   DACGDM010000165 DACGDM010000000
VERSION     DACGDM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.173"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            129..1169
                     /locus_tag="IXR05_002819"
     CDS             129..1169
                     /locus_tag="IXR05_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAQ4261253.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            1993..2325
                     /locus_tag="IXR05_002820"
     CDS             1993..2325
                     /locus_tag="IXR05_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAQ4261254.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            2944..3285
                     /locus_tag="IXR05_002821"
     CDS             2944..3285
                     /locus_tag="IXR05_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAQ4261255.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1258 a          458 c          643 g         1021 t
ORIGIN      
        1 ctgattttag gtagtattta attaaaaaac agttttaatg cgtttgcatt ttttatttat
       61 ctttgctatt ttcgaaaaga gtaggtaatt ttacataaat aaaacaacgt gaaagtagag
      121 gatctacaat gactgatttt aaatttttta aggcggatag agtttacaac gaattatttt
      181 atcaatttcc aaaagtcttt attgtttctg acgaatacaa aaaaatgaaa gattcaacta
      241 agattgccta tatgctttta aaagcaagat tagagatcgc aatcagcaaa cggcaaatcg
      301 atgaagaagg taatgtttat tttacttata cgacaaatga actatgtaga gtattaaact
      361 gccaaaaaca aaaagcgata gcaatcaaaa aagagttgga atcctttggt ttattattac
      421 aaaagcagat gggatttaac aaacagttag ggaaaaataa tcctaataga ctatatctag
      481 cagaattaaa agtctcagaa aatgatatct acttactcga aaaatttgat agagagaata
      541 gggaaaacgt tgataaatca gagggtatga aaatcatacc caccctcgac gaaaaatcag
      601 acgctgaatc ccttggggct caagagggta tgaaaatcat accgtgccaa aacgttgata
      661 aatcagaggg tatgaaaatc ataccagaac ttaataataa tatattagac actaatagac
      721 acaatataga cactgaaaaa gaccgcctac aagatcaatt gttgttagac aattttgaga
      781 caattatgac aaacgacagc attgctacgt ttgtccctga acgagtatta aatttgataa
      841 aaacattttc ttcaagttac agtgaagctc aaaaaaccgt ccagactatt cataatgcaa
      901 agaaaaaagc tgaaatagaa agtggtattt cgatagtttt tgaagaactc gatagttatt
      961 atgtcaatgc agaacaagaa ttatacacga cactgttaaa agcctatcaa aaattaaaaa
     1021 ccgaaaaagt cgaaaatatc cagaacctga tttttgtcta tgtaaaaaat tggtttatcg
     1081 aaaaaccaat agctgctaaa gtatcaagtg aaaaacgttt gaattatgaa agctccccaa
     1141 gcactattac gaaagactgg ttagagtgaa actttactga caaagtgatt gttgcttcat
     1201 ggagtaacat taaaattaaa aattttttat tattctaatt atattacgaa tattacaaaa
     1261 taatagctat tttaatagaa tttataagtt aaaatattat gataaaaatc acaaacgtag
     1321 ccttttacgt cataagtgtt aaaagaaata attaatttca aatatagaaa agggaacgta
     1381 tgtttgcata ctcctttttt ttgagttata ataatacgcg aagagagata atttcattat
     1441 ttaaacaagc taaaaatctt gatattactt cttttcaggc aatacgaata ttattcgctt
     1501 acattttttg tataaattta attgtctgct atgcttgtga tgaattgatt ttcgttctgc
     1561 acttttggat gataaatttg gacaattgaa aatacaaaaa aaagaaaggc ggtatgaact
     1621 cggaaggctg gtaaccttcg tcagcgttca tacacggcat taagatttgg cccttaatgc
     1681 gttaaccttt cagtgttacg gtattacccg caatggattt agtataacag atattcaaaa
     1741 gtgataccac tttttttggc tgtgttaagg ttaaaaatac gtgatattac gatgaatcta
     1801 tgcctaagca caatgttata aaaatgtccg tgtggctctt tgccgtatga cgaacgctga
     1861 aattagaggg aacgcatgtt tggatgcgtt ccctcttttt tgtttgtcat gaacgaaaat
     1921 caattctcta tttttgaaaa ataacaagaa aaacttgtta aaaatattta aagaaattgg
     1981 gtggtttatt ttatgtcata tacaggaatt ttgagtctca aagatatttg tcactacggt
     2041 aaacggtgta ccgctacaga gaaaatcacg aagaaactat caactggcca aagtaaaacc
     2101 gttgtgcagt gtaagaaata tataatccag aaagacaaag tctcagagga aatgatttat
     2161 tacattggga aacaaaagca aataatttta aaagatccta tccccttaaa agagctatat
     2221 ccaacaatca aacatgttta tgaccaaaac ggtgtactga ttggtcgaag aaaaaatgga
     2281 gtcttgcgtt gtaccgcaaa agggatgggg cgtttgatcg gctgaattga tcattctcat
     2341 aacttgtatt ttatcgtttt tcgcttgctt gaaaatattg tcgagacttc taaaggaact
     2401 tagagtcact agaaaaataa ggagtagact tgatctatca acaattccct tcggggagtg
     2461 acggggtagg ttttaacgat tggtaacgta aaaaattggt caatcgagta aatgcgcttg
     2521 tttggatagt ggtgaaatga atttgtgtaa ataataagcg cagagtaaac aagagggaat
     2581 ttagaagtta gacaagttag aatagcgtct agattaatca tgagcagcta ctaagggatc
     2641 tagactttga cgcaaactca tggaataagg agtaggtctt ctcgtaatgg ggaggacgca
     2701 caagaaattg tgtcgtgtgc tgcagtacat gtagatactt gcgaggacgt tgattattgg
     2761 atcaatcgag catttaccgc tgtctactag ggtttctcgt ttcggacgcc ataaacgagt
     2821 cgaaattttt tatgtatttt taagtaaacg aaaaacgata aaatatgaac aagtcctgaa
     2881 taaagtgaaa aaattgatat aaaacataga gaaaatgaaa tttacgtaat ggaggaatga
     2941 caaatgaaaa attatgatcc gaatatacga ttgggcacac atactattaa ggtttctttc
     3001 caacgttggg attacaaagg atttgtgacg tttagaagag gcggaaattg taaaggatta
     3061 gatgttttag cattagacga ggatgattta tacgatcaaa cattgactga taatccaatt
     3121 ggattcggct tgctacctga agatgatgaa ggtaatgaat ggtttaaaat gacgcttatg
     3181 aatgataatg gagacgaatt atctgttgaa gatacttggt catatttgag tgattatatt
     3241 gtcagctttg aaatcattga atttgtagcg gataaagaag aataaaaact ggaggaataa
     3301 attttacaga taaaggctta gaaggagtca cgatgattaa taaaaaggta gtattacctt
     3361 aggcattgag taaggaattt
//
LOCUS       DACGDM010000166         3367 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.174, whole genome shotgun sequence.
ACCESSION   DACGDM010000166 DACGDM010000000
VERSION     DACGDM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.174"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            77..1765
                     /locus_tag="IXR05_002822"
     CDS             77..1765
                     /locus_tag="IXR05_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261256.1"
                     /translation="MKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRI
                     KGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNI
                     CTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYY
                     AYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFV
                     VVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDI
                     TTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLL
                     QFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVI
                     QSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKA
                     ADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIE
                     ITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1752..>3367
                     /locus_tag="IXR05_002823"
     CDS             1752..>3367
                     /locus_tag="IXR05_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261257.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFK"
BASE COUNT         1158 a          490 c          553 g         1166 t
ORIGIN      
        1 tttaacgcaa aacttattaa aaaaagacaa ttctagtata ctgaaaatag aattaaaaaa
       61 ggagaacaac aaatctatga aaataagtaa aaaagcattt cttttagtag ttcttatctt
      121 acttagtact ttatattcag taaattttat gagaaatgct caagaaattt atacaacagg
      181 tgatttatct tttcatcttt cacgaatcaa agggttatct tctatttttg aagggccaat
      241 caactataca acatttaaca attatggaga tggactgaac tatttttatc cttttcttac
      301 aataattcct gcagtcgttt tttatggaat ttcaaataac ttaatattaa gttatgttct
      361 atatatttgg ttattaaata tttgtacgat tctgattagt ttttattatg gagaaaagtt
      421 ttttaaaaag atagatgctg cttttttatt tagttgttta tatacttttg caacttatcg
      481 aacagttgat atctattatc gatccgcaat tgcagaagca atcgctctta cgattatccc
      541 agctgtttta tattatgctt atggattgat attcaataga gaaaaaaaag tcatcgcttt
      601 atctgtcagt ataagtctac ttgtgtatac tcatgtctta actacactat tgtgtagtgc
      661 attgattgct tgtatgatta tagttcgttt gtttttaagc aagcaaataa aaaacgatat
      721 aaaatttgtg gtcgtgaatt tagtaaaggc tgtttttttg acttgtgcat taactagcta
      781 tttttggtat cctatgttgc agcagatgaa ttatcaagaa atacacagtc ccttcaaaac
      841 agatttgcag ctagaagcac tttctatttc agatagtatc attcaagcgt taaataacga
      901 tattacaaca tacactatgg ggttattagg attggttgcg ttgatttttc ctttattcat
      961 actgaaagaa atggagaaaa aagaaaaaat catctatgtt ggcgtagttt ctacatgggt
     1021 atgcgtaact aatttatttc catggttttt gtttcaaaaa acaccgataa gcttactcca
     1081 gtttccttgg cgtatcttag gtatccaaat ctttttttct tcaatgatca taacgcttgt
     1141 ttttatgaaa aagactatga ataaaaaata ttcatggtta atcattggcg ctactgtggt
     1201 gtttctactc gtcacgtcta tagcagcaaa agaaaattac gcaaaagtta tccaatcaaa
     1261 acacggtcat attgttatca atgaagaaac actcccacgt tatacaacat cagatatggg
     1321 aggattatac gattacgccc caacagaagc gataaaagaa aggcctcact tagaaaaaca
     1381 tgaagtaaaa gtaggagaat cgtgggaaaa agggaagtat aaagctgcag ataataacat
     1441 tacttacaca gtggcaagca acaaaaagca aaaagtgaca gtaccagtat atgcttattt
     1501 aggtacacag gtaaaagtaa acggtaaagt cgtaaatgac tcttataaaa aacatggctt
     1561 agtgaatgtg gatgtaaatg ctggagaaaa taagatagaa attacaacaa aatatactcc
     1621 aactgctctc atggctttat ggatcagtat tctgacttat tgtttagtgg tgtattcaag
     1681 ttttaaacga tttgcaccta ataagttgaa agattctcga tatgtgacta aaaaggagat
     1741 aaacaagaag aatgaaaata aataaaaaag tagtaatatt gagtggatta attatagtta
     1801 gtagtatata ttctttcatc tttttcaaaa atacacagag tatttatacc actggagatc
     1861 tttcttttca cttatctcga atcaaggggt tatcgactat ttttaccagt ccgattaatt
     1921 atgagacatt caattatact ggatatggtg taaattattt ttatcccttt ctgacttttt
     1981 ttccagctgt aatgttatat tggatgacaa aaaatttgat tgtaagctat attatttacg
     2041 tttggttatt gaacttgtgt acaacactcg tagcttatca ttatggcgag cggtttttaa
     2101 aacaaaaaaa agcggcattt ttatttagtt gtctctatat tttctctgct tatcggacag
     2161 tagacatcta ctatcgttcc gcaattgccg aagctatcgc aataacactt gttatccctg
     2221 tattatttta tgcttatcaa atcatctctg gaaaagaaga aaagtatccg tctgtaaagc
     2281 tagcattgag tatgagtttg ctagtgtaca gccatgtact atcaacatta atgagtacag
     2341 cattaattat catttttatt tttattcgtt tggtttctaa aggtttcaag aatgcagatt
     2401 ttattgctat atttaaaaaa ttatttagtg cggcaggaat gacattggtt ctgacgagtg
     2461 ctttttggta tccgatgttt gaacaaatgc tctaccaaaa aatcaacaaa cctagcgtga
     2521 caaatttata tgctcatgca tctaatgtgt tcgatagtct gactgaagct atgaacaacg
     2581 acttaactac ttactcaatg ggactagttg gtctgttatc tttatgtatt cccctgattt
     2641 tatttaaaaa attaacaaac atagaaaaaa agatttatta tggtacgtgt ttgacttggc
     2701 tagctacaac tagtttggtg ccatggtatc ttctgcaaaa tacgccagcc aaattgttac
     2761 aatttccttg gcggatctta agcttgcaaa taatattctc ttctctgata ttaacgatga
     2821 tatttttcaa aaatagaaga tacaataaga caagagaact attttattta tttatgactg
     2881 ttttgttatt aatcacttta actgtttcta gtaaaaaaaa tttcaatcaa aaaataattt
     2941 ctcagccggg acatattgtt gtaaacaaag aaacagtaga ggcgtatacc actaaaggaa
     3001 tggattattt tttatatgat tattctccta tcgcttcatt ggagaataag gagcatataa
     3061 taaaacacga agcaaagatt ggcagtcaat gggtaaacct tccttataaa acaactggta
     3121 gttctatcat atatagagta actaatgaga agagccaagt aatcacactt cctgtatatg
     3181 cttatttagg aacgaatgta gaaataaatc atcaacctgt aaaggagcag gtgaatgcta
     3241 atggattggt acaaataagc ggagtcaaag gagttgctga tattaaagta agcacaagtt
     3301 atacagtaac gactattatt tcttatcttg ttacattaac tgcatattta tgtttatttt
     3361 ttaaaat
//
LOCUS       DACGDM010000167         3309 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.175, whole genome shotgun sequence.
ACCESSION   DACGDM010000167 DACGDM010000000
VERSION     DACGDM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.175"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(800..1756)
                     /locus_tag="IXR05_002824"
     CDS             complement(800..1756)
                     /locus_tag="IXR05_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261258.1"
                     /translation="MLILANQASTFVQTQQLRGRGLRLGAQNKVTNIWHLAIGLPGVP
                     LSEQPDLKRMLRRLGNISGLTFESSPKIESGGDRFALPLEYTTTTMETYTQSMFYFSC
                     ERSRLKEQWSTALADGWHLSMPIVVRKVDQVKQKQETSLPIVVKNIEPLSFWSAIFKG
                     NLLEYFQIRRRQKLWEKECARKKSLAICVQTTLQRLGEVSDRKVIVAADQQEFRCYLE
                     NAGYREGQLFTEAMRELLAPLENPRYLIEGKKIVLTVPERFGRNKQIANLFLNELNQS
                     SLPKCQLVYTRNPEGRQKLVTYRMRQVFQTRDEVIIQKNIWT"
     gene            complement(1865..2110)
                     /locus_tag="IXR05_002825"
                     /pseudo
     CDS             complement(1865..2110)
                     /locus_tag="IXR05_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2255..2677)
                     /locus_tag="IXR05_002826"
     CDS             complement(2255..2677)
                     /locus_tag="IXR05_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261259.1"
                     /translation="MVKEEVLCPHQDFLYLIPANQETTQHYFTFLEKQNELVEALMES
                     QETVDYLLSLEFVQHPLEHSKEIYENFELFTSALIYLNHHNYELIPEHWQLLGSSKQQ
                     GKKASVPSLGKKELITIYQQMFEDQPELPIFYQLKKAG"
     gene            complement(2816..3246)
                     /locus_tag="IXR05_002827"
                     /pseudo
     CDS             complement(2816..3246)
                     /locus_tag="IXR05_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347687.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         1006 a          715 c          541 g         1047 t
ORIGIN      
        1 tgattactac agaaaactaa ctactttttt tatgtaaagt tctgtcaaat atagtcactt
       61 tatattactt tctcttgagt aaaaaaacat gtgaggtcgt aaacaaagat tgaactatct
      121 acattcatac tctataatct gtttatttgc agactgataa tagcaaaaga aaacttataa
      181 tcaaataata tcaacatttg atcacataat ttgagattga atgctgattt acctatgttt
      241 tacgtaatgg tctttagtta tttttgctca taaaatgcat aaaacacgcg tttttatgtg
      301 tgcttgaaat ttcttggctc tataatttct aagactgata aaaatattct atcggttctt
      361 tttgcaaata aaaaaacata tagaagctcc attagattga atcaccacaa cacaatcaaa
      421 ggagcattcc gtatgcttga ttttcattct ataaaactac ttttaggaat caaagaaaat
      481 cacaacggtt caaactaaaa gcaagaatat ccgaagtacc attgtttcat cgatcatgag
      541 aaaagcattc acctctgtct gcagatgttc ttatatcgct ctgtcagtcc tattaataaa
      601 gtactgtttt gttttcaaaa aaactattac gagtactttt taagagaatg ccttgcaaat
      661 attcatcaca caccgttata taagtcaaat agtttctttc agtcgtcaag aaaagattct
      721 cctgtccttg gcattatcag ttaagtagca acttaattct cggacttgtt ctactctagc
      781 aaaatttatt ttcatcaact tacgtccaaa tgtttttttg aataattact tcatcgcggg
      841 tctggaagac ttgcctcatt cgataagtca ctagcttttg gcgtccttca ggatttctag
      901 tatacaccaa ctgacatttg ggcagcgacg attgatttaa ttcgtttaga aaaaggttag
      961 cgatttgctt atttcggcca aagcgttctg gtaccgtcag aactatcttt ttcccttcga
     1021 ttaaataccg cggattctcc agcggtgcta aaagctccct catagcttca gtaaaaagct
     1081 gtccttctcg atagccagca ttctcaagat agcatctaaa ttcctgctga tcagccgcta
     1141 cgattacttt tctatcacta acttcaccaa ggcgctgcaa cgtcgtttga acgcatatgg
     1201 ccaagctttt tttgcgggca cattcctttt cccatagctt ttgtcgccta cgaatttgga
     1261 aatattccag caagttacct ttaaatatag ctgaccagaa gcttagaggc tctatatttt
     1321 ttactactat cggcaatgaa gtttcttgtt tttgctttac ctgatcgact ttcctaacga
     1381 cgattggcat agataggtgc cagccatcag ctaaagcagt actccattgt tctttcaacc
     1441 gacttcgttc acaagaaaaa tagaacatcg actgagtata agtttccatc gtggtggtcg
     1501 tatattccag tggtaaagca aagcgatcgc caccactctc aatttttggt gaagattcaa
     1561 aggtcagacc tgaaatattg cccaaacgcc gtagcattct tttcaaatca ggctgttcag
     1621 acagaggaac tcccggtaat ccaatcgcta aatgccaaat gttcgttact ttattttgtg
     1681 cacctaggcg taagccccgc cctcgtagtt gttgtgtttg cacaaaagtg gaagcttgat
     1741 tagccaagat caacagatta attgcaggac aatcccagcc ttctcctagc aaactaacgg
     1801 ttcctaccaa aatattcaac ttcttttcgg ttaataggcg agtaactgct tgcatcaatg
     1861 cttggcggtt tttgtcatcc accgtcaaat aaaaataacc cgacatataa ggatgttcat
     1921 tcatacccgt cgctagttct gccagctcaa cagttactag cattttcggt aacagtaaga
     1981 actctccaca gatggcaccg atttgctgag tgttacctaa tagacgaaca acttcatcaa
     2041 acaaaggaac cacgccataa gctaaggtac catcactgcc tgctaatacc tccttgcaaa
     2101 tacgatccat caaaatgacc gctgtcagtt cttgcttcag ctgaacttct tcttttaaca
     2161 aaatttgaca aactgcttgc tttttctcag gaatcgcctg actaccaaca gtgtctggat
     2221 actctggaaa caaatgcagc gactcatcaa acaatcatcc agcttttttc aattgataaa
     2281 aaataggcaa ttccggttga tcttcaaaca tctgctgata aatagtgatc agctcttttt
     2341 tacctaaaga tggaactgaa gcttttttac cttgctgctt agaactgcct aatagctgcc
     2401 aatgttcggg tatcaattca tagttatgat gattcaagta aattaatgca ctagtgaaca
     2461 gctcaaaatt ttcataaatt tccttcgaat gctcaagcgg atgctgaaca aattctaaag
     2521 aaagcaaata atccaccgtc tcttggcttt ccattaacgc ttccaccagc tcattttgtt
     2581 tctctaaaaa ggtaaaataa tgctgagtag tttcctgatt agccggaatc aaatatagaa
     2641 aatcctgatg aggacataga acctcctcct ttaccaactc gggaatgcta atttcttcgt
     2701 caatcaggcc attttaactc aatatattgc ttccactccg tctgagagct atcaatcgga
     2761 ggcgtggctg tcaaggaaat cgtcaacaga ttcggttgtt ttttcttcaa gtcaatcaac
     2821 aattcacccc agcttttttt taaatgatga gcttcatcaa aaaactaaca gctccagctg
     2881 atcaccataa gttggctcct ccttcagtcg gttgtaaatg gtctgatacg tttccactgt
     2941 aatatgacta ggatgttcaa tcgccccaga aagatagcaa ctatctgctg gatttactaa
     3001 gaaatattcc tcgattgttg ttaaccactg tttcttcaat attagggaag gaaccaaaat
     3061 taaggtttta caatccaaac gtcggatcat ctcaattcct aaaaaggtct tgccagcccc
     3121 tggtggagcc actagatgga ctgaattgtt atttaaataa gtagcaaagt tagtcaatat
     3181 acgcttctga tagctacgcc actgaatttt ttcatcagat agccacatcc caggtccccc
     3241 tctcacgtat tttctctatc ataatctaaa tgaatacagc aaaaaaaaga tttcttcaag
     3301 aatatgtgt
//
LOCUS       DACGDM010000168         3248 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.176, whole genome shotgun sequence.
ACCESSION   DACGDM010000168 DACGDM010000000
VERSION     DACGDM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.176"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..466
                     /locus_tag="IXR05_002828"
     CDS             <1..466
                     /locus_tag="IXR05_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAQ4261260.1"
                     /translation="MEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEE
                     YLTILKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETA
                     LNKIQDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            439..1116
                     /locus_tag="IXR05_002829"
     CDS             439..1116
                     /locus_tag="IXR05_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4261261.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1106..2248
                     /locus_tag="IXR05_002830"
     CDS             1106..2248
                     /locus_tag="IXR05_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAQ4261262.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2261..3238
                     /locus_tag="IXR05_002831"
     CDS             2261..3238
                     /locus_tag="IXR05_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4261263.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
BASE COUNT         1213 a          411 c          621 g         1003 t
ORIGIN      
        1 aatggaacaa caatctcaac caattatttg cattttacct aatagtgatg ctggtagcga
       61 aattatcaga aaaatgtacc agaaatattt aaaaacggat attatttata ttacgaattt
      121 agagccggag gaatacctga ctatattaaa agagtgcaaa tttatgatcg gaaattcttc
      181 ttctgggata attgaagctg catcattcaa aataccagta ataaatttag gaaccagaca
      241 aaatggacga gaacaatcta aaaatattat aaatgcaaat ctaaatgaaa atgaaattga
      301 aactgctttg aataaaatac aagatcctca gtttataaaa agcttgaaaa atgttaagaa
      361 catctacggt gacggcaaca gttctagaag aataacaaaa acattgaatc aaatattgaa
      421 tgatggggaa gatattaagt ggattcaaaa acaaatagct tattaaaata tactagtgat
      481 ccatacatta ttattggggc tggcggacac gcaaaagtca ttattgaaac cttaagatta
      541 gaaaataagt taatatatgg attttttgat gataagcaaa ataaaatgca agatctgaaa
      601 tatcttggga aaataaacga attgaatagc tgggcggata gcaaaaaaaa aatctataaa
      661 tttattgtag ctattggtga ctgtgtagta agaaaaaaga ttataaaaaa attgaatatg
      721 ccaagtgagc aatatggaat agctgttcat ccaagtgcta tagtggcaaa agaaatttca
      781 attggttatg gaactgttat ttttgcgaat gctgtaatta acccagatgc tgtaattgga
      841 gagcatgcta taataaacac aggtagcatt gttgagcatg attgtagaat taataactat
      901 gttcatttat ctccaggtgt atgcttagcg ggtggagtac atgtaggtgt aggaactcaa
      961 ataggaattg gttctcaatg tatccagatg aagaaaattg gatcttggtg tatgataggc
     1021 gcagggagca ctattgttaa ggatattccc tcacattcct tagcttatgg caatccagct
     1081 aaaattaaga aagaaggaat taattttgaa ttctagaatt ttattatcaa gtcctcatat
     1141 gggaggaaca gaagaaaaat atgttgctaa ggcttttaaa gataattgga tagcgccatt
     1201 aggtgaaaat gtggataaat ttgaagaaag tattacaaaa tatactggtt ctaagggcgg
     1261 agcttctgcg ttaagttcag gtacagctgc catacatctt gccttaagac tgcttaatgt
     1321 tggaaaaaac gatattgtct ttgctccttc atttactttt atagctacag taaatcctat
     1381 tttatatcaa ggggctgtac cagtgttcat tgactcagaa cctaatacat ggaatatgag
     1441 ccctgttgca ctagagagcg cattagaaga agctgaaaga aacaaccaat tacctaaggc
     1501 aatcatcgta gtgaatttat atggtcaaat ggctgattat gaacgaattt tagctattgc
     1561 aaaccaattt aatgttccag tgatagaaga tgcagcggaa tcgttaggtt ctacttataa
     1621 gggaatttcg tcaggcttat ttgggacaat tgggatctat tcatttaacg gtaataagat
     1681 catcacaacc tcaggtggag gagctctagt gtctagtgat aaaaaatatg ttgagcattc
     1741 aagattttta gcaacacaag caagagatca agcaccgtat tatcaacata gcgaaatagg
     1801 ttataattac cgtctaagca atatttctgc cggtatcgga cgtggacaaa tggaagtatt
     1861 gaatgataga gtagctaaac gaagagaaat tttcaatcga tataaggaag ctttttctgg
     1921 aattgataga attgaaatga tgccagaagt ggatggcatg gtgccaaatc gttggttgtc
     1981 tactttaacg atcaatgatt ataattctat tgatcaagta gttaacgtaa taaataaact
     2041 aaatgaaaaa aacattgaaa caagagcttt gtggaaacca ctacatttgc aaccagtatt
     2101 tcaaggggta aaaatgtatt accatgataa taatcttagt gtgtcagaaa agttatttaa
     2161 tagcggctta tgcttacctt ctggaagtaa tatgacagat agtgaacaag aatttgttat
     2221 tgatgagttt aaaaaaatat tcaagtaggt gtgatatttt atgaacatag gaattattgg
     2281 tttaggttcc atggggaaaa gaagacttag actcattcaa gaacacttta atgatatttt
     2341 actatgtggt gttgatacta atgaggcgag acgaaaggaa gttgaaaagg aatttggaat
     2401 accaacttat aatagtctaa cagaggcaaa aaatttgttt gaaataaatt cagtttttgt
     2461 ttgtacatcc cctataaccc atgaatttat tataaaagag gctttaaatt tagattgtaa
     2521 tatctttacg gaaatcaatt tattaaatga atattatgat gaaataatcg aagtagctaa
     2581 aaagaaagat agattacttt atctatcttc tacatttttg aagagaaaag aaattcaata
     2641 tattaagtct aaagtgacgc ataataaaaa aatttcttat caataccatg taggacagta
     2701 tttacccgac tggcatcctt gggaagatta tcgcaatttt tttgtttcaa acaaaaaaac
     2761 taatgggtgt agagaaatat tcgctattga attaccttgg attatagata catttgggaa
     2821 agttaaatcg tttactgtaa tgacccagaa attatccaat cttgatattg attattcgga
     2881 cagtttcact cttattattg agcatgaaac tggtatagtt ggaactttaa gtgtagatgt
     2941 tgtttcaaga gtagctaaaa gaaatttaac tataattggt gaaaagattt taatagaatg
     3001 ggaaggtaac ccggattctc tattttcatg gaatgaagaa acttctagta tgacagatat
     3061 tcaattgtac gatgaggtta tgcatgataa taattattca catactatta ttgaagatgc
     3121 atatttagag gagattaaag aatttttcac gcttttggaa aagaaaatgg aaccccaata
     3181 tacttttgaa aaagataagt atattattaa cttaattaac gacattgagg taaattaatg
     3241 atgaaagt
//
LOCUS       DACGDM010000169         3225 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.177, whole genome shotgun sequence.
ACCESSION   DACGDM010000169 DACGDM010000000
VERSION     DACGDM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.177"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(553..2166)
                     /locus_tag="IXR05_002832"
     CDS             complement(553..2166)
                     /locus_tag="IXR05_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAQ4261264.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="IXR05_002833"
     CDS             complement(2307..3215)
                     /locus_tag="IXR05_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261265.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1038 a          555 c          572 g         1060 t
ORIGIN      
        1 gttaaataaa taggaacaaa aaaattaaat tatttaatac acacattagg gatcattcat
       61 tgaaggatta gaagacaacg aggatggcga aaaatatgat tacaatagaa aagtcgttct
      121 aaaccaatca gttcctagta tcacacaacg caagccagtc gatttggtga gattagagga
      181 gtgaaagcaa actttattat ataagaaaaa atattcgaaa gggatgctag tttaggtact
      241 agtgctgata gattaatatg atgcctcgta atattaggcg tagttactct agagacatca
      301 ctatggacta tgatttgtct cagagtcaca acatgttttt ttatgaaaag aaacagctaa
      361 aataattaaa ttgcgcaatg tttaaacttt cttaaactat aacctaataa atgtgaagaa
      421 ataatgcaca atttcttcac atttatcttc tattctatat acataccaac caacaaccct
      481 atatactttt tcatttttac tcctcaagta aaaataactc ctagaccgcg gctacccacc
      541 gcggtcgttt ttttattctt caatcaaaat cgctttgata cccaaacctg ccaagattcg
      601 ggcagaagta taagtattca atcctcttct gaaagtaatg taaacttttt tatcttttgg
      661 gatttcattg attcgatctc gtaactcatt cattggaata ttttttgttg ccgagatact
      721 gccagaaggt gctttattag gttcacgtat atctaaaaag aacgcttctt tcaaatcgtt
      781 ttcgggtata tcacttgctt tgatcgtttc tacgatattc gtcatttgat tgattgcgac
      841 ataaccagct atattcaacg ggtcacgggt agtagaatac ggtggagagt aaggcaactc
      901 caaatcaggc aaatcaaaga ctgtcaagtt tccggtgatt gctacagaaa gttctcccat
      961 ccgtttatcg acaccttttt ctccaaatgc ttgtccacct aaaatacgac cgctatctgc
     1021 atcaaaaatc agctttagat ttaatcttgt agcttctgga tagaaatagg catggtcaaa
     1081 gggagtgata aaaacagttt tataatttgt tatgcctgat gcttttaatt catgttctgt
     1141 cattcccgca taacttgctg tatgatcaaa gatttttgcg acacctgcac caatatatcc
     1201 gcgatagcgc ataggcgtac catttaaaat atctgccagc atatgtcctt gacgattggc
     1261 cgcactggaa agcatacttt ggatcggctg accagtcact acactagtcg tttcgataat
     1321 atcgccaatc gcatagatgt ccggcagatt ggtttgtaac tggtcatcaa caatgatctg
     1381 acctgtatct gataattgta tgccggttgc tttcaccact tcattcttcg gagaaacacc
     1441 aacagcaaaa attagcatat cagcagaaag gacggagcca tctgataata ctatttctcg
     1501 acctttatca cggatctcag taactcttgt ttctaaatga acggctaatc cttctttcag
     1561 caatttgtca taaactaaat tagcaatttc tggatcataa gggaaagcga cttgtggcaa
     1621 ttgatcgatt aaagtcacgt ctaagccgcg atgcttgaaa ttctcagcta attccagacc
     1681 cataacacct gcaccaagaa tgacgacatg ttgtggattt ttttcttcaa ggaacgattt
     1741 gattcgatcc gcatccgtca cactacggag gacaaagccg ttttctgctt caaaaactcc
     1801 gggaatatcc ggataatctg gtctagcacc agaagagatg atcaacttat cgtaatctgt
     1861 ttttatttct tcatttgtgg ataggtcttt aactgttaat cgcttagtag aaggatcgat
     1921 tgctgttact tcgtgtttag taaagacatc gatgttgttt tttgttttca atatttctgg
     1981 tgtacgttcg atcagcgagt cacggtcagt gatcacacct cctaaataat aaggcaaagc
     2041 acaacttgca taagaaatat tttctccgcg ttcatagata atgatttcgt gcgcttcatt
     2101 caatcgacgg aaacgagtgg caaatgaagg accgccagct acaccgccaa tgacaacaac
     2161 tttcataaaa acatctcctt ttctacgttg atcgtactat gttatggtaa aaaacagcaa
     2221 ataattgtgc cggaaaatta ttgtttattt tgaatagaca gaaaatatag agaaataatt
     2281 tgtggataaa acctaaaaat ttttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttct
//
LOCUS       DACGDM010000170         3209 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.178, whole genome shotgun sequence.
ACCESSION   DACGDM010000170 DACGDM010000000
VERSION     DACGDM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.178"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            106..414
                     /locus_tag="IXR05_002834"
     CDS             106..414
                     /locus_tag="IXR05_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAQ4261266.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            441..740
                     /locus_tag="IXR05_002835"
     CDS             441..740
                     /locus_tag="IXR05_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAQ4261267.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            914..1465
                     /locus_tag="IXR05_002836"
     CDS             914..1465
                     /locus_tag="IXR05_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAQ4261268.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            1611..1904
                     /locus_tag="IXR05_002837"
     CDS             1611..1904
                     /locus_tag="IXR05_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261269.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            1897..2193
                     /locus_tag="IXR05_002838"
     CDS             1897..2193
                     /locus_tag="IXR05_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261270.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            2264..>3209
                     /locus_tag="IXR05_002839"
     CDS             2264..>3209
                     /locus_tag="IXR05_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAQ4261271.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVY"
BASE COUNT         1206 a          449 c          642 g          912 t
ORIGIN      
        1 gtataaaatg aatcaaattg aatatcaaat atatattata tccatgaagc ccaatcttct
       61 ttaatagaag attgggctat ttttatggca aaggagggaa aagaaatgtt tcaaaataaa
      121 ggacaacgtt atgtcacaaa gggagtaatg gacagtttgc cggtggaatt acaagcttta
      181 tgttggaatc taatcgatca aaacgttcaa aagcaatttc atttagacta tcttcaaatc
      241 tttgaatttt ctacggaaaa aggaaatcaa aagttggttc atcgtcaaga agaaccagaa
      301 gcaagaaaag agtatctgat ttcacctaag cttcgtttga aatcagtgtc tcaaaaaata
      361 tgggtcattg attcgggtga gtatcaaacg atgttattac cagaagaata ctgatatcta
      421 aaagaaagga acgaaaggac ttgttagaaa cggctatcga agtactggaa aagtgtgcac
      481 agctagtcac tactcctgaa gagtggggct atgaatccgt tacgatggaa aaagaggaaa
      541 ttgaaatggg tatgcttcct gaagatgtta ctctaccacg tttagtgatg acacatcttt
      601 atatttattg cgcaccagaa gatggaaaag actatgtagt ttatttcatt acagatatta
      661 ccagccagcg agaatttgtt cgtgggttac tggtagaagg acgattggtt tggagtcaga
      721 ttggaggaac gaatgaataa gatcgattat ttgagaatga ttgcgaaatg tttagaagat
      781 atccttacag cgattcatca aattctgaag aaaaaaggag aaagaatatg aaatattttc
      841 aactagtatt gacacttata acggcaatgg tgattgaatt gcttgaacaa aaattagcat
      901 aggagaaaaa gagatgattg aaaaagaatt agtgaccaca caaacagaag tttggcgaga
      961 tcctcatcat acccatcgct atgttttcaa acgacaatgg gcgatcaaag gaaaagaagc
     1021 ggaagataaa ttagcggtag tcattactat tcgtccaaca gatacagaac catttacgaa
     1081 tgatttgagt atgttattaa tcgaaaagaa tatccgacaa ttaggattta ctggttttat
     1141 tgctgtgaat cttttttcgt atacaaaagc gaaaagtcct cgggtatttc ctcgtggaaa
     1201 tgatgaacaa tctttggaaa tattaacaac tgttttcaca gaaaagaaaa tcaacaccat
     1261 tatttttgct tgtggttcga ttacagcgac gagtcaagtg gcttatgaac aagcgaagac
     1321 catttacgat caattgagtg cgaaacaaaa aaagatgacc aaagtattga taaatgcaga
     1381 aggtaagtta tcccacccac taagtattca tgttcgtaat gaatggcaat tggcagatag
     1441 tcaattatta tttcaagaaa aataacattt tattttctta tgttacttat aagtagtttt
     1501 acatgctttt tgactttaaa aatacatgtg atgatacatg ttatatgaat tatcaatgta
     1561 cccagtaata tgctattttc attatgtaaa aaataacagg gggtgtgtag atggagattg
     1621 atgaaacttg tttgagtaac tcttataaaa gtatgaatga cttttttgag gaaatggaac
     1681 tggattcaga attgctctat caattttatc ttgcttttcg agggcaacag atttcttttc
     1741 caatgaaaat gtacgatcgt gagttagtta gaaaaagaat cgaaaacatg atagaacagg
     1801 aaaaaactgt agatatccgt caattgacag aagtttatgg tttctctgca agatggattc
     1861 aaaaagtaat taaacaaaaa gaaaggagac gagtacatgg ctaagctgat tgtattaggt
     1921 ggtttaattt acggtggata ttggttatat aaatatatgc ttgcgcatcc gaatatagat
     1981 aaaggaaaag taattaagac agttggggta atcatagttg gactcatagc tctaactaag
     2041 aaaaataata ctaatagccc aaaaataatg agaacttatc gctgtagagg atgtggaagg
     2101 gaaatttcta ctagttttaa tccatctgaa agccctcaag gaagagatcg ttgtcatgct
     2161 ggctatcgac attcttggga aaggattaac taaatgaaca ccattgagat taattgactg
     2221 ataaaataag tacgcgaggg agaaattgaa agggggaaat aaaatgaaaa aatggttgtt
     2281 attactaatt ggaatgggga ttttattcac tggttgtaca tctgagaata cgaggactaa
     2341 agagactgta gaaactgata caacaattga ggctaaaaaa agtaaaacgc aatcaactga
     2401 acaaactaca acagaaatga aacaatctgt ggaagcaagt acaagtgaaa gttcaatcat
     2461 tgaatcttct tctgaagagg ttaaaaatac tttgtgggat agtgagaaat ctactcaact
     2521 agcaattttt gtcccacaat ggggaaagac attaggtcaa gaatataaaa gctacaatcc
     2581 tcagaacaat gtaagtctgt atggtacgcc tttaccaagt gcagttattg atggaaattg
     2641 gaaaatggca atcaatgaag caccagttac cgtacaatgg tcagaagatg gaactggtca
     2701 tgcagatttc aatttagtag cagtttattc tgatgtagaa actggagaat atttagggca
     2761 gcatgtatat ttctttggct ttcaaaatgg acaacctaaa gtttatttaa cgcaacaaaa
     2821 tcaaggcaat gataaaaact acatgtactt caatgaaact cagaaccaac agttaaaaca
     2881 aggtttcatt gatattgtga atggacaaac tcctcaaact ccagtagtag aagaatctac
     2941 tcaacaagca acaactacaa cgacacaatc tacaagtagc tcagcaattt caagttggga
     3001 agctgctaaa gaaactgtac taaataataa agctttatgg ttgtatgatt ctcctgataa
     3061 aaatgcatca aatactaatt taattagcac aaatgaatat atgaaagatc taatgcaaga
     3121 tgaaaatgga agctactatt caattaatat tgtaacggat gataatggaa atacaacaat
     3181 ggctggtgga aaacaattcc gtgtttata
//
LOCUS       DACGDM010000171         3194 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.179, whole genome shotgun sequence.
ACCESSION   DACGDM010000171 DACGDM010000000
VERSION     DACGDM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.179"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            133..822
                     /locus_tag="IXR05_002840"
     CDS             133..822
                     /locus_tag="IXR05_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAQ4261272.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            836..2338
                     /locus_tag="IXR05_002841"
     CDS             836..2338
                     /locus_tag="IXR05_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4261273.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            2351..2827
                     /locus_tag="IXR05_002842"
     CDS             2351..2827
                     /locus_tag="IXR05_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAQ4261274.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(2924..3034)
                     /locus_tag="IXR05_002843"
                     /pseudo
     CDS             complement(2924..3034)
                     /locus_tag="IXR05_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1056 a          430 c          618 g         1090 t
ORIGIN      
        1 tccattatac tccaaaataa taaaaaaaac tcctaaatac tccattttta tctttacttt
       61 tatgaaagcg gatgctatat tgtttttgga gttgttatcc aaaaataata aaaaattgga
      121 gtgtttagga taatggataa aaagaggttt ttagatctta tttcaaaagg tttgattgtt
      181 tcctgtcaag cattacctgg tgaaccattt tacaaagagg aagaaagttt aatgccttat
      241 tttgctttgg ctgctcaaag ggctggagca gttggtatac gtgcaaattc tgttcgagat
      301 attattgaaa ttagaaagtg tgtatcatta ccaatgattg gaattattaa aagagattat
      361 ccaccagaat ctccattcat tactgccact atgagagaag tagatgaatt agtagaaacc
      421 ggtgttgagg taatcgctct tgattgcact cttagaaatc gacatgatgg actatctata
      481 aattctttta ttactaaaat aaaagaaaaa tatcctcatc agttatttat ggcagatatt
      541 tctacatttg aagaaggcaa aaatgcatat aaagcaggaa tagattttgt aggaactact
      601 ttaagtggat atactgagga aagtaaaaaa caagatgggc cagatataga tttgattaaa
      661 aaattggtag aagaagggat ttgtgtaatt gctgagggaa ggattcatac tccagaacaa
      721 gcaaaagaga taaaaaaaat aggagttgca ggtattgttg tgggtggtgc tattactcga
      781 ccacaggaaa ttgcatcaag atttgttaaa gcattaagtt agggggagaa ataaaatgtt
      841 taaaaaattt tcacaattag gacgcgcttt catgttacca attgctatat taccagtagc
      901 cggattacta ttgggactgg gaggagcgtt aacaaatgag agtgctataa atgcttatcc
      961 atttttagat caaccgtggt tgcatacaat tttaagtatt atgagttatg ctggaaatgc
     1021 agtttttgca aacctagcac taatttttgc aattggtatt gctgtaggac ttgcaaatgg
     1081 agataaagga acagctggtt tagctggtgg agtagcttat ctagtatata ctgcaactat
     1141 tagtgggttt cttgaacttt tttcagcaaa agatgcaaca ctagatacag gtgtagtggg
     1201 atcaattgtt gttggtggta ctgttgcatt tttacacaat cgttatagaa aaattgaatt
     1261 accacaattc ttaggttttt ttggaggatc aagatttatt ccgattgttt ctagtttagc
     1321 tgcaatcatt attggttctt tcttttattt aatttggcca ccaattcaaa atggtttagt
     1381 agttgctggt gaacaaattg cccaaatggg tagtttagga acttttttat atggtttttt
     1441 attgcgttta acaggtgctg ttggactaca ccacaccatt taccctttgt tctggtatac
     1501 atctttaggt ggtaccgaaa ctgtagctgg atcaacaatt gctggagccc aaaatatttt
     1561 ctttgcccaa ctagctgatc caaaccacac tggtctgttt acttatggta ctagattttt
     1621 tgcaggaaga tttgcaacaa tgatgtttgg attaccagca gcatgttatg caatgtatcg
     1681 tgcaattcct aagaaaaatc gtaaaaagaa tggtgggctt tattttagcg gggcccttac
     1741 atcattttta actggaatta ctgaaccagt tgaatatatg tttttatttg ttgctccttg
     1801 gctttatgtg attcatgcat tcttagatgg attatctttt tattttgctg atatcttaaa
     1861 tattcgtgta gggaattcct tttcaggtgg tttgatcgac tttttattat tcggtgtact
     1921 tcaagggaat gacaaaacta attggttaaa attaattcct tttggtattg catgggcatt
     1981 tatatatttc tttgttttta cattctttat caaaaaattt aaggtagcta ttcctggaat
     2041 ggaagaagaa tcagaagttc attctgaaaa agtaataaac aaaaatacat cattacatga
     2101 agagtctctt atcattattg aagctcttgg tggaaaagaa aatattgagt ctgttgaagc
     2161 ttgtgcaact cgtttgcgtg ttgctgttac gaatggggag attattcaaa aacaaacaat
     2221 aaaagacact ggtgcaactg ctgtcttcga agtgaagggt ggcatccaag ctgtttttgg
     2281 agggaaagct gacttattaa gtcaagaaat caatcaaata ttaggaaaag ataattagga
     2341 ggtttttaat atgtttgaaa ttttcaaaaa gaaaaaacaa gaaacttttt atgcaccttg
     2401 ttccggaaaa atcatttcca tcacagaagt aaatgatcct gtcttttcac aaaaattact
     2461 aggtgatggt tttgccgtca tacctgatgg ttcaaaaatt tatgctccat tggctggtcg
     2521 agtaacaaat atatttccta ctaaacatgc tattaatata aaaagcaact caggcattga
     2581 ttatttgatt catattggaa ttgatacagt tgaattacaa ggagagcctt tttcgatttg
     2641 tgttcaagaa aatgatgagg ttactcctga aacctcgttg gttgatgtgg attttgacaa
     2701 aataataaaa tctggtaaag atacttctgt tatagttgtt tttccggaga aaaatcagtt
     2761 caatgattta ataatagata atggtcgaat tgctcatggg aattcatgtg gaaaaatcac
     2821 tttttaaaaa agtgtatata aaaagctata aaataagcta aataggatat ttgtcaaatg
     2881 aagttggtga acagaaagaa ctgttttctt tctgttcatt tttttatttt attagtaatg
     2941 attccccatg ccaaatcatg atccgtaatt taaagttata aaagcttcga aatccattgg
     3001 catttcgttg gaataccttg atatgattat tcaaatataa aatatagaga gaagagagag
     3061 agggaagata tttataaagg gcaaagttat gtttactcaa cttaggaaat agaaatagat
     3121 caatttatat tctcttgtca atcgaatatg aaccttagca ctatatacca aatatagtaa
     3181 aatgctgaaa gatg
//
LOCUS       DACGDM010000172         3129 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.180, whole genome shotgun sequence.
ACCESSION   DACGDM010000172 DACGDM010000000
VERSION     DACGDM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.180"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            103..1347
                     /locus_tag="IXR05_002844"
                     /pseudo
     CDS             103..1347
                     /locus_tag="IXR05_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            1360..1992
                     /locus_tag="IXR05_002845"
     CDS             1360..1992
                     /locus_tag="IXR05_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4261275.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            2197..2424
                     /locus_tag="IXR05_002846"
     CDS             2197..2424
                     /locus_tag="IXR05_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAQ4261276.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            2493..2759
                     /locus_tag="IXR05_002847"
     CDS             2493..2759
                     /locus_tag="IXR05_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4261277.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            2749..3018
                     /locus_tag="IXR05_002848"
     CDS             2749..3018
                     /locus_tag="IXR05_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4261278.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         1102 a          466 c          617 g          944 t
ORIGIN      
        1 tgaaattgct ttcctttaaa atgactcatc gtcattcctc ctgctatctt tttctattat
       61 tctaccttat ctgatagtag atttaaaact ttgcaacaga accagaaaac caaagatcag
      121 cttaacgaat tttttgctaa tgttcttgaa accccttatt ggtatgcaaa aaaaatctta
      181 agccttttat ctgagtgttt agatcaacct gtgtatgaag aggacatttt ctttattacg
      241 ctatattttt atagtttgaa tgtcacgaat gttaaaacag gtattaagag tattgtgcta
      301 gctcatggtt attctacagc tagtagtatg gcgaatgttg ccaaccgtat gctgaataag
      361 aacgtttttc aagcttatga tatgccttta gatattacat tagagaaaat tgaagcaaaa
      421 ttgattcaat tccttggaga ttatcgaaca gattcaggct tgattttatt ggtagatatg
      481 ggttcactaa accaactagg cggtttatta gtgaatcatc taaatggacc actgttaatc
      541 attgatcata tcaatacacc gttattattg gaagtcggcc aacaagtatt aaacaataaa
      601 agtatcaccg aaataggagc agaaattgaa acaagtctta ctttcaaaaa gcagttacta
      661 cttcccaaga aaaagaaaaa gaaagccatc attacttgtt gttatacagg gattggtagt
      721 gcgacccaga ttcaggagat tttaacgaaa tgcttgaaag atgcagttag agaattagta
      781 attattccgt atgattacaa aaagctgtta gaaaacaaga attttgagac tccttttcaa
      841 ttatacgatg tcatcatgat tgtaggtaca gaagatccca aaattaatca gattccatat
      901 attggattag atcgcctgat taatggggga agcattggcg aatttgttca ttacttggaa
      961 aaagagctga ctattgaagt gaacgattta caaaaagaat taattttcaa tttttcaatt
     1021 agtaaaattg tcgaaaattt aaccattttg gatccagata aggtgctatc ttttgtacaa
     1081 aaagcaatta aagaattatc gaagttatta aattttgatt tttctaataa tcagctgttt
     1141 ttgttgtaca ttcactgtag ttgtatgatt gaacgaattg tacgtaaaga aagtgtggat
     1201 gagcaagagg acattgaaga atatatgcaa gcaaatggag aaataatgga taaaattcat
     1261 agcgcttttt ttgagattga aagggaatac acaattgaaa taccagattt agagttgcga
     1321 ttattgagcg atattgttca aggataggag tgaattcgaa tgacaatggg agtaattttt
     1381 gatatggatg gggtactcat agatagcgag acattttatt ttgagagaag aatgaacttc
     1441 tttcaagaac tggagataga tccaggatca aaccagattg atgattatgt ggggaaaaca
     1501 gaagctgcaa tatgggaaac attagttcct gaggacaaat cattaagaga ggaactttat
     1561 ccgaaatatg tagattatcg aaaaacgcat ccaattgatt tcgctaaagc tttacgaaaa
     1621 gaagtgaaac cgttacttga cttcctcaag aagcgggata taccattggc actggcatct
     1681 tcttctccag ctgtcgagat agagagtatg ctcattcaat gtgaacttac tgaatatttt
     1741 tcctttgtta taagtggtga gtcattaaaa caaagcaaac cacatcccga aatatattta
     1801 aaagcgaaac agcaattaga ctgtgacttc tttattgcag tagaggattc aacgattggt
     1861 attaaatcag caaaggcagc aaatatctat acggcggcac taaaacaacc aatgcaaatc
     1921 gatcagagtg aagcagacat acaaattgaa agtctacaag aactggaaca aattgtttta
     1981 gaaaaaggtt agtgaattaa tggaaataag gctatatatc tgtgctagct attttgacta
     2041 accaaaaaaa cttgctataa ttcaggtgta gtaaaaggtg ctggtaacac cttttacgaa
     2101 aatgcttcgg cagtgataat gggattggct ttttaagttt tttattttgt tcgcaatccc
     2161 taaggtcatg tgaatgatcc tagggattgc tagaatattt tgcaacagaa ccaaaatacg
     2221 aatagttatc aagcagccat attgactgcg gtcaatttag gaggggatac tgatactact
     2281 gctgccgtaa ctggtgctct tgcgggtatt ctttacgggg gtgaagtgat ccctgaaaat
     2341 tggagaaaat cgcttcaaaa tgaccagctt cttaaaacga tcagtcagag attttgcgat
     2401 accgtgctat ctcaaagaat ttgaataatg gatatgatgc aaatcttgtt tgtactaacg
     2461 ttgtattgac aaaaaggatt ttatttagta caatgttagt acaaatgatg aacggaggta
     2521 gaatcatgtc tcaatcaacc attacattta ggattcccga cgatgaaaaa gaactggtat
     2581 tagaatatgc aaaagcacac aattcttcat tgaccgaact ttatcgaaat gctgtactgg
     2641 ataaaatcga agatgaaatc gatctacgga ctttacggag tgcaattgaa gtttccaaag
     2701 agaaaaaaga gagtggtatt tctcaagagg aaatggagaa actgctaaat gaattataaa
     2761 gtcatctaca tgccgcaagc ccagaagcaa ttaaaaaaaa tggacagaaa ccaagctaaa
     2821 ataattgtcg cctggatcag aaagaattta gaaaacacga ctgacccgcg tcagcacgga
     2881 aaaggtttga ctggaaataa gagtggggaa tggcgctatc gaattggaaa ctatcgaata
     2941 ttggctaata tttgtgattc tgaaattgaa atccagatat tctcaattgg acatagaagt
     3001 acaatatata aaagataacc gtttttggaa cgaagtagag tttcgaaagt caatgtataa
     3061 tcttttgaat tttgcataat accacaggta gaaactaccc gatactatcg gttggtttct
     3121 gctttttta
//
LOCUS       DACGDM010000173         3013 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.181, whole genome shotgun sequence.
ACCESSION   DACGDM010000173 DACGDM010000000
VERSION     DACGDM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.181"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            177..359
                     /locus_tag="IXR05_002849"
     CDS             177..359
                     /locus_tag="IXR05_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAQ4261279.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            462..746
                     /locus_tag="IXR05_002850"
     CDS             462..746
                     /locus_tag="IXR05_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261280.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            762..998
                     /locus_tag="IXR05_002851"
     CDS             762..998
                     /locus_tag="IXR05_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261281.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1020..1274
                     /locus_tag="IXR05_002852"
     CDS             1020..1274
                     /locus_tag="IXR05_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261282.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1356..1541
                     /locus_tag="IXR05_002853"
     CDS             1356..1541
                     /locus_tag="IXR05_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAQ4261283.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1608..2003
                     /locus_tag="IXR05_002854"
     CDS             1608..2003
                     /locus_tag="IXR05_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAQ4261284.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            1993..2370
                     /locus_tag="IXR05_002855"
     CDS             1993..2370
                     /locus_tag="IXR05_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261285.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            2371..2766
                     /locus_tag="IXR05_002856"
     CDS             2371..2766
                     /locus_tag="IXR05_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261286.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         1058 a          507 c          523 g          925 t
ORIGIN      
        1 tttatgttta tgtatatgta tatgaatata aacgtattag gtacgaacac ttttaaattc
       61 ttttctgggc tttgttttta gggtagggct aaaaaaaaca tcaccatctg atccaaaaca
      121 gctcagaaac gcattttaac gtatctgata ccaatattac agaaggagtg tatcgtatga
      181 ttaacctatt tcttttagtg acagctagta cattattctt tactggaata tcactgataa
      241 tttcctattt gatctataag aaagccgaaa atcacacaag caaagcaatc ggactagccg
      301 tttcatcctt tttaactttg ctgactttat ttgttacttt atcgttttct tttgtttaga
      361 acagctgatc cattagcacc tttttctctt tacattatac acactgttgt gtataatgta
      421 tttgtaaaca agctaattaa cttttaggaa ggagtgacaa gatgctaaca gctactttac
      481 agcaacctac tcacgttgct attgcagaaa gttatacaat taatgcaggg atcgttaaac
      541 agctgatcaa ggatcgagaa ttcaaaaagt ttaacagtcg gcaagcgtat aacagacagc
      601 taaagaaagc tattctaaag cacaaagatt ccttcatcgg gaacttggaa agtgtagatg
      661 ttaaaactgt ttcaacggca ttttcagttg ttgaagtgac tattgacggt cgcttgattt
      721 ctctatttgc ttttggaatt aattgatagg gagtgtgaac tttggaaggt aagacttttg
      781 cagaaatttg gactgaattt attgaggtac caactcgcat tgatccgata acttctgaaa
      841 aggtattgga tgcagacttc tacaatctca aagcaggtac tagccttgaa tgcgtttgga
      901 tgtatttaga agagcatttc aaaggcgtaa cgctcggtca cgtcttatac cacaatggtg
      961 ccgagtggga tgcaattgga aatatccatt tttcttaata taagaaagga gaacacaata
     1021 tgaattatac cgatgaagaa caaatcgctt tggaatacgt tttcacaaat gaagaagggg
     1081 aggaaattga aaaagtcttg atcatttcat caaaagactt ggagaaggct ttggcttatg
     1141 aaccatacga atcaaccgta actgtcattg aattcttaga tacctatact tctaatgata
     1201 cttgggaaat tatgaatatt tgcaacgcta ataacattca atttgctgaa aaaaccaata
     1261 aatcatttta ttagttttgc aataaaacat cctctttttc tattgattcc atacacaaca
     1321 atgtgtataa tagattttgt aaagggaggg tagctatgcc taagacagca agagaaattg
     1381 taaaaattct caaatctaac ggcttcaaaa agactggaca aactggcagt catgcaaaat
     1441 tttataattc caagactaaa agaacggtcg ttgttccgat ccacaatggt gatgtaccac
     1501 taggaacaga agctaatatc tggaagcaag cagggcttta acagccttgc cttcctattt
     1561 ggtattaggc atactatcct ctcttacact agaaaaggag cgaggaaatg aagacaaaaa
     1621 atatttttta tccggcaatc ttcgagaaag aaggagaagc ttataacatc gttttccctg
     1681 acttaccgga aatatctacc tttggaaata gtcttgaaga agcatattta aacgctaagg
     1741 atgctttagg attagcgcta tatagtgtac cagatgcaga atttcctaaa ccatcagcag
     1801 tggaagaatt aactttgaaa gccaaccaag tggtagtaat catccaacta aacattaaac
     1861 ttttccgaag aagcttaaat acaaaaacaa ttagaaaaaa tgttagtgtt ccggaatggt
     1921 tagttctttt agggaaggag aaaaacataa acttctctca actacttcaa aaagcactag
     1981 aagaagagtt gcttgaaaag taaaaaggag accgaaccta tgaaagctac acacttaaac
     2041 tatttctctc gaacgttaat caataatcta ttaaaagata caactggcat tagcgttagt
     2101 accaaacact ttgccaatga tctaattatt tttgaggata ataacttgcg aattgagatg
     2161 tttattgaac aggcaacccc taactcaata cctgaattct gctatacgca cactgaaaaa
     2221 atgaaacatg caaaatcagt taaagatgtt gaagcattaa gtgaatcact aacgaacgct
     2281 ttaaacctcg ttaagaaggc aaaattgtta tttgaatttc aaaccgacta ccacaatgag
     2341 ttgcttgctc aatctgaaat tttagattaa ttgaaacagg agaagagaaa gatgaaacaa
     2401 acacaaacag aaaccgttaa cgatacgctt gctgatcaat tagcaggtta ttataaatta
     2461 tttgagatgg gtaaagcaca gcgcttgatc cactatcttt ggaaatacaa aattttgttt
     2521 cttttttggg aatcaacact aacattctca gttctttttt ataagtcaga tttttataat
     2581 caacacttag ttttagggag ttttttgctt atctacacca ttttgatgct taatttatat
     2641 acctacatca cacttgaaga acacttagta attagcgatg cagggatcga gagaaacatc
     2701 aaaagggtat ccttcaagat cacgttaaac aagcctaccg ataaaaagct ctcagaagcg
     2761 ttctgagagc ttttgacatt ttcttgtata attttatcct aacacattac aaagcaccta
     2821 attcgagctt atatcaagca aatttgctat ttattactca atacatatct aaaaattact
     2881 tgatggaaaa ttagatacat ggtaagcatg aaaagaaaat caatttgagc agatgcagta
     2941 caatacatag caatttaaaa gctctcagaa ggcttctgag agcttttaat atattctttg
     3001 ataatttgtc ttt
//
LOCUS       DACGDM010000174         2963 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.182, whole genome shotgun sequence.
ACCESSION   DACGDM010000174 DACGDM010000000
VERSION     DACGDM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.182"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(37..1257)
                     /locus_tag="IXR05_002857"
     CDS             complement(37..1257)
                     /locus_tag="IXR05_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4261287.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1882)
                     /locus_tag="IXR05_002858"
     CDS             complement(1277..1882)
                     /locus_tag="IXR05_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4261288.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="IXR05_002859"
     CDS             complement(1931..2863)
                     /locus_tag="IXR05_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAQ4261289.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
BASE COUNT          810 a          620 c          515 g         1018 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttg
//
LOCUS       DACGDM010000175         2940 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.183, whole genome shotgun sequence.
ACCESSION   DACGDM010000175 DACGDM010000000
VERSION     DACGDM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.183"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..1097)
                     /locus_tag="IXR05_002860"
     CDS             complement(<1..1097)
                     /locus_tag="IXR05_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4261290.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVGGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENA"
     gene            complement(1227..2603)
                     /locus_tag="IXR05_002861"
     CDS             complement(1227..2603)
                     /locus_tag="IXR05_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4261291.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2603..>2940)
                     /locus_tag="IXR05_002862"
     CDS             complement(2603..>2940)
                     /locus_tag="IXR05_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4261292.1"
                     /translation="ADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPII
                     LADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKK
                     VNKMNLEVE"
BASE COUNT          893 a          565 c          412 g         1070 t
ORIGIN      
        1 gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga gtgaatactt
       61 tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc aaagagttgt
      121 tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg agaccaccga
      181 ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact gtagaatttt
      241 ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa cgcatttcga
      301 acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt tgcgccttct
      361 ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc acctactttc
      421 agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag ccataggcct
      481 aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc atattcttta
      541 gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa tgcataacac
      601 ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc cgtgatatca
      661 gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc ggcgatatcg
      721 cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc ggagacatct
      781 cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct gggaacatca
      841 atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt tcgtcgattg
      901 tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt caattctcct
      961 tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg catatcctct
     1021 acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc atcaggattt
     1081 cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa ataaaaaccg
     1141 tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta cactctcatt
     1201 tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc ttttggattc
     1261 cttcttaata tattgaatga agaaataatc aatgatacaa gaagtactaa actcataaat
     1321 ataactacat aaatcatgaa tttaggtaat acattgatat ctaaacttga taatgtcttg
     1381 ttaaatcctt cagcttctgc cccaccacct aattggctag atgcagattg tttagctatt
     1441 tgtttagcta tatcaccagt aaccttattc aatatattat tcccaagctt gtcagctgta
     1501 tattgagcta agaaatagga accaacgaat gcggggattg atataaatac catctcaatt
     1561 aggaattgac caaaaatttc taattttgat atacctaatg atagtaatac tgctatttct
     1621 ttctttctag cattcatcca taagaataat aataatgaaa ctacaactcc tgcaaatatt
     1681 aatgagccaa aaaataattt atttgaaatt gagtaaatac ctgatataga ttgttgtaat
     1741 gcagggtaat ttgatgaact tttaatcaaa ttatattctc tccaatttat atctaatttc
     1801 ccaagatctt ttattacact atcaagattc ttatcacctt ttacaaagaa tgttgcatct
     1861 tggtatacag ctgtatcttc ggtattacca taaactttag cagctgtatg aatatcagtg
     1921 attaatgtat tttcgtatag ttcttgtgct gcacttactc caccgctatt atgcccatcg
     1981 aatagacctt taatttctac ttctactgtt tcatctgcac ctttctcatt atcagcatca
     2041 aataaattag attttatttt tatcttatct ccaactttaa ggttattttt ttcagctaaa
     2101 tctttatgca ttaagatttt atttttatct tcattttcta aatgctttcc ttctactaat
     2161 ttatatgctt ctgatacaaa ttttgtttct tttgttgagt cgttaacccc agttaacata
     2221 actgttcttt taaaattctt tgctctttca ggtgattgat tcgcaagagt ctcttgagtt
     2281 tcaataatat cataatcaac taaatctgca acactgttta ttctttttac ataggagtct
     2341 atactatctg tttgagatat ctttttaata tcttcacctt ttacatttcc cccacctcta
     2401 ggtgttcctg gatttacttg tctatttatc tccatagaaa aactatttgt tatattagca
     2461 aatgtttctt ttgaagctct gtccgtagca tctttaatag ataaactaat gagacttaaa
     2521 gttgacatag ataaaataac taatatgata attaatgatt ttaaactttt tctagttaca
     2581 taagcaaatg cattttttat cattattcaa cctccaaatt cattttattt acttttttca
     2641 actttttacc acttagttct aaaatgatat ccgcagaatc tgctacttcc ttactatgtg
     2701 ttacaactat tacacattta tttctatctt tagctaatgt ctttaatata ttaattattt
     2761 ctccagcagt aacactgtct agattaccag taggctcatc agctagtatt attggagcat
     2821 ctgataccaa tgctctagca atagctactc tttgttgctg tccaccagat aatttcataa
     2881 catttctttt tatttgtttt ttatctaaac ctagttcaaa caagatactt tcatctgctg
//
LOCUS       DACGDM010000176         2875 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.184, whole genome shotgun sequence.
ACCESSION   DACGDM010000176 DACGDM010000000
VERSION     DACGDM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.184"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..1382
                     /locus_tag="IXR05_002863"
     CDS             <1..1382
                     /locus_tag="IXR05_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4261293.1"
                     /translation="GGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIE
                     VTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGT
                     TVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKV
                     TTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEV
                     DVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTA
                     GNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTV
                     TLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSG
                     KNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLG
                     YKNRKKENE"
     gene            1516..2859
                     /locus_tag="IXR05_002864"
     CDS             1516..2859
                     /locus_tag="IXR05_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4261294.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
BASE COUNT         1127 a          393 c          559 g          796 t
ORIGIN      
        1 ttgggggcac agtagatcta acagataatg ttactaactt gccagcgtta ccagaaggaa
       61 caacagtaac agatgttact cccggcggta caattgatac caacacacca ggtaattacg
      121 aaggtgtcat tgaagtaacg tatccagacg gtacgaaaga tacggtgaaa gttccagtag
      181 aagtgacaga caatcgttct gacgccgata aatatgaacc aacagtagaa ggcgaaaaag
      241 tagaaattgg aggcacagta gatttaacag ataatgttac taacttgcca gcgttaccag
      301 aaggaacaac agtaacagat gttactcccg gcggtacaat tgataccaac acaccaggca
      361 attatgaagg tgtcattgaa gtaacgtatc cagacggtac gaaagatacg gtgaaagttc
      421 cagtagaagt gacagacaat cgttctaatg cagataaata caatcctgaa ggacaaaaag
      481 tgactacaga cttaaataaa gagccagatg catctgaggg aattaagaac aaagaagatt
      541 taccaaaagg aactacttat gcttggaaag agaaagtaga tgttagcaca gctggaaata
      601 aaaaaggtac tattgtagtg acatatccag atggatcatc tgatgaagtt gaagtagacg
      661 ttacagtgac agatactcgt tccgatgcag ataaatataa tcctgaagga caaaaagtga
      721 ctacagactt aaataaagag ccagatgcat ctgagggaat taagaacaaa gaagatctac
      781 caaaaggaac tacttatact tggaaagaaa aagtagatgt tagtacagct ggaaacaaaa
      841 aaggtactgt agtagtaaca tatccagatg gatctaaaga agaagtagaa gttactattt
      901 ctgtagtaga taaaaaagca ccgaataaac ctcaagttga tcctattaca gagggtgacc
      961 aaattgttac tggtaaaact gaaccaaatg cagaggtgac agttacatta ccagacggaa
     1021 gtcaacacca tgggacagct gataaaaatg gtaattttac agttaaagtt cctaaattag
     1081 aggcagggac aaaagtgata gtaactgcaa ctgatgaatc tggtaatact agtgaaccta
     1141 ctaatgtagt tgtttcttcc aacaaaaaag acagtggaaa aaacggtagt aaaggtagta
     1201 agactgacaa tcaaggtagc aacagcaatc aagacaaaaa tagaggcaaa agccagtcct
     1261 caaaagtttt tcctaagacg ggagagagtg acagtaatat ctttactatt agcggtggtt
     1321 taatactgtt aggaacgtta ggattattag ggtataaaaa tcgaaaaaaa gagaatgaat
     1381 agaaaatcaa tttcttaagt cttctctgag aagaggaaga atctttttct tcctcttttt
     1441 gcttttttat gatgggaaat aagtgttagt taaagatgaa tatacttttt atagaaagga
     1501 aaagaatgta attaagtgga aaaaatagta attattggtt caaaccattc agggctagcc
     1561 gcagctcgat ttctaaactt aagcgattca aattatgaag ttattctaat cgataaaaaa
     1621 tcagaaatta gttacttgga atgtgggaca tcgttattta taaaaggaga agtaagtaat
     1681 ttagaagatc ttttttatca aaatagaatg acactaaatt ctgagataaa aaagttattt
     1741 ctagagacag aagttgacaa aattgatatt caaaataaaa agattagttg tgtaaaaaaa
     1801 gatggtacaa gattctctca agaatatgac aaagttatat tagctacagg ttcaaagcaa
     1861 attatgctag atataccggg gaataattta gctaatattt tttcgataaa gaattttcca
     1921 aatgcaaaag agatttttaa agctttggat gatagtacta ttaaaaaagt aggaattatt
     1981 ggagcaggat atattggagt tgaaattgct gaagccataa gaaaaagagg gaaagaagta
     2041 tatcttttcg atgttgcaga tagagtgttg tcgacttatt acgaccgtag tttttcagat
     2101 aaagttgaag aaatactatc aaaaaatgga atacatcttt gtctatcaga aagtcctaaa
     2161 aaatatttag gaagaaaaaa gattgaaaaa atagtcacta caagtggtac ccaatactct
     2221 atggatatgg tcgtacaagc tataggattt ctatctaata gtccaattgg ggaaaaggaa
     2281 ctcttgagag atgttagtgg agcatatcta actaatgaat accagcaaac aaatataaaa
     2341 gatatatatg ctattgggga ttgtgctaca acttttttta cgtccattaa tagaagtagt
     2401 gttgattttt ctatttctaa tgctctaaga acagcttata ttgcaactca acatattaac
     2461 aatcaagatt ttacaccttc tggttcccaa tttacaaatg gcttttctat atttaattac
     2521 aatttttacg cagcaggttt gaatttaaaa acagcacgat tattaagtga gtctatagat
     2581 tatatagaaa tagaagattt cattagacct gcttttttga gaaaaaatag tcgtgtaaaa
     2641 ttaagaatta gctttgaaaa aaatacaaag agaatagtag gtgtacaact ttgtagtcaa
     2701 gaagatttat ctggactatt atcaatgttt tctcttgcta tagaagaaca aattacatta
     2761 gacaaattga aaatgttaga ttatttattt catcctagtt ttagccaacc ctataatttt
     2821 attttaaagg cagtaacagg attaaacatt gaaacataat cgttactaaa tgaaa
//
LOCUS       DACGDM010000177         2826 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.185, whole genome shotgun sequence.
ACCESSION   DACGDM010000177 DACGDM010000000
VERSION     DACGDM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.185"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            798..1064
                     /locus_tag="IXR05_002865"
     CDS             798..1064
                     /locus_tag="IXR05_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261295.1"
                     /translation="MAKITKNEQENLVENYTKKPAYSNSRLDAHFVCTSNPKLSFDAM
                     TIVGNLNKNSAKKLSDFMSLDPQIRLWDILQTKFKAKALQDPLC"
     gene            1122..1634
                     /locus_tag="IXR05_002866"
     CDS             1122..1634
                     /locus_tag="IXR05_002866"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003321317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4261296.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLY
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            1631..2668
                     /locus_tag="IXR05_002867"
     CDS             1631..2668
                     /locus_tag="IXR05_002867"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4261297.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1022 a          496 c          564 g          744 t
ORIGIN      
        1 ttgatgacca cgaaagtgca tggcgatatt tgatgttgat actttatgca gtaccctatg
       61 tattcttcgc tatcattctg tggctcatag cattgttttt tagagtattt aatgaccttt
      121 aggtagattt atatataaaa agggctaaat acgcaaaata cccccttaaa atgcaaaata
      181 aatgcaaata agggggtaac tccttatgaa aaaacaacta atagtattat aacacgtttt
      241 tatgccgaga aaacttattg gttggaatgg gctatgtgtt agctaacttg ttagcgagtt
      301 ggttggactt gaattgggat taatcccaag aaagtaccaa ctcaacaaca cataaagccc
      361 tgtaggttcc gaccaataag gaaattggaa taaagcaacg aaaggagttg agtaaaatga
      421 gtgagaaaac gaagaaaatc attcgagtat cattagcttt ttcacaagta gtagtgcaat
      481 cattgatagt ttattatact taccagcaat ataaattatc taaagagaat taagttttga
      541 ttatgtaata agttttggta ctaaaaaaga cttgatctaa ttagaccaag tcttttgtta
      601 gtgttatatt aataacaaaa taaaaataag aagtcgctca ctccccgacc aaagtttgtg
      661 agcaaaataa acagtcgatg tttgtttctt aattgtatat cttgatatta aacgatttaa
      721 gattattctt caagatatat attcgcaaat gtaattggaa aagcgacttc ttaaacaaaa
      781 ttaaggagtc gctttttatg gcaaaaataa cgaaaaatga gcaagaaaat ttggtggaaa
      841 attacacaaa aaaaccggcg tactctaata gccggttaga cgcacatttc gtgtgcactt
      901 ctaatccgaa attgagcttt gacgctatga cgatagtcgg aaaccttaat aaaaacagcg
      961 ctaaaaagct atccgatttt atgagtttag atccacaaat tagactttgg gatatacttc
     1021 aaacaaaatt taaagctaaa gcactacaag accccctatg ttaggctagt tgtcgtatag
     1081 gataataagt tataataaag actatacgga ggatgattac catgacaaat aaaaacaatg
     1141 aacgttactc taccgaactg aaagcgacag ccatcaagaa aatgatgcca cccgaaaata
     1201 gggggattcg ccaattaagt caaactttgg gcattccaga agcgactctt tattcttggc
     1261 gtaaaaaagc tagaattcaa gggaatacta cacccggaac gaaaaaaaat gtcgaaaaat
     1321 ggtcaagtga agataaattt ttaattgtga tggaatcatt ctcaatgaac caagtagaac
     1381 ttgcggaata ttgccgaaag aagggcttat ttaaagaaca aattgaggct tggaagaaaa
     1441 cgtgcttatc tgcgaatgaa caggaagaaa atcgaacgag agaacttgca actgaactaa
     1501 aagaagagaa aaaacaagcg cgtcaattag agaaagaatt acgtcataag gaaaaagcat
     1561 tagcggaagc cgctgctctc ttattactaa gaaaaaaagc acacgcgatt tggggggacc
     1621 aagaggaaga atgatttcat cttcagatcg caaacaagct gttgaactta ttcaagaagc
     1681 caatcgcaat ggggcccgtc tcacctatgc ctgtaatgag ctgaatatta gcgttcgaac
     1741 ctacgaacga tggacgcgtg aaggtacgat agcgcatgat caacgccctt tggcgaaacg
     1801 tcctgtaccc aaaaataaac tgacggatca agaacgcgaa aaaataatag aaaccgtttc
     1861 aaaaaaagaa tttatgaatt tgccacctag ccaaattgta ccaaaacttg cggattgctc
     1921 gatttatatt gcatcagagt ctagcttcta tcgtgtattg cgagaaaaaa atatgcaaca
     1981 tcaccgtggc cgaagtcaag tttcacaaaa acgcataccg ccaagtcacc ttgcgacgaa
     2041 gccaaatgaa gtttggactt gggatattac ttggctaaaa ggtccaataa aaggactctt
     2101 ttaccggtta tatctcatca ttgatttatt tagccgtaaa atggtaggct gggagatttg
     2161 ggaatcagaa gaagctcgtc atgccgaaaa acttattaaa cagacggtgc ttaaggaacg
     2221 tatccaagga cagccgttgg ttttacactc cgataatggc agccctatga aagccgcgac
     2281 ttttcaagtc ttactcgaaa aattaggaat tcaaagttct tattcaagac cacgagtgag
     2341 taatgacaat ccttattcgg aagcggcttt ccgaacgtta aaatatcgac cagaatatcc
     2401 caataacggc tttaaaacaa tagatgatgc tcgaaaatgg acgaaagagt ttgtcgattg
     2461 gtataacgat tctcatttgc atagtgggat tcaatttgtg tctcctgcag cgtgtcatga
     2521 aggacgacat ctcgctattt tagagaaacg aaagcaggtt tacgaggacg ctaaaaagcg
     2581 ccatcctgaa cgctggtcaa aaggtgttcg aaattggact ccacatcaat cggtggcgtt
     2641 gaatccttta aaagaaacag aaagttaaca ggagcataat ctttcaagat tatcaaataa
     2701 ccctcgtcac ccaatagggg aaaaagttat tcttccccta ttggataacg aggccaaccg
     2761 accataggga ggttctgctt tttgataggt ggaaaataaa aatacgacaa ctatattgac
     2821 aaacac
//
LOCUS       DACGDM010000178         2439 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.186, whole genome shotgun sequence.
ACCESSION   DACGDM010000178 DACGDM010000000
VERSION     DACGDM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.186"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            135..2288
                     /locus_tag="IXR05_002868"
     CDS             135..2288
                     /locus_tag="IXR05_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAQ4261298.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          833 a          427 c          540 g          639 t
ORIGIN      
        1 attgctgtga aacaaaaagt tgattttatc ttgaaattag gtaaagaatt tcttgctccg
       61 cccatttttt cttttttatt aagaagtttt tgggtacaat gaagcatgaa tgtaaatagg
      121 cggaaggata ggaaatgatg aaagatttta tgaaaaaaat attaaatact tcttggttag
      181 aaaaaataag aaaaggtgca caagaaccta agaacaaaac gtttcgccgg tcccatgttc
      241 cttttcgctt aaattttctt tttttcatta tatttacgtt atttgttgcg ttgattgcta
      301 gattgggtta tttgcagatc gtgaacggcg aagagatgga ggcgcgagtg aagtctactt
      361 ctacgattac ggtccaagaa agtactcctc gcggaatgat ctacgactcc acaggaaaag
      421 ctttagttac gaataaagcg aatcaggcca tcacatatac gagaggaaca caagttacgg
      481 ctaaagattt gcttgaaatc gcaacgaagc tgaactcgct gatcgatgtt ccggtagatg
      541 aaaatctgac agatagagat aaaaaagatt tttggctggc tgatcccaaa catttgaaag
      601 aagccacaaa aagactttcg gcaaaagaaa agcaattagg gaacagcgaa caatatagtg
      661 cgatggtcaa taaagtcaca gctgatgaga ttaatttaaa cgaggagcaa ttaaaaattg
      721 ctaccatctt taaacggatg aatagtgcat atgaattaaa cactgtctat atcaaaaact
      781 ctggtgttac tgatcaagag ttagctgttg tggcagaacg cgcttctgaa cttccaggag
      841 tttcgactgg cacagactgg acacgagaat ataatgcagc aagttcactg aaaagtattc
      901 ttggcagtgt gacgactgaa aagcaaggac ttccagcaga tgaagcagag aaatacctag
      961 caaaaggtta ttctcggaat gaccgtgtag gacaaagtta tttggaaaaa caatatgaag
     1021 atgtcctgca aggaaccaaa acccaatatg aagtttccct tgataatgaa ggaaatgttt
     1081 cgaatcaaaa agaaatcttc tctggggaaa aaggttctaa tttaatgtta tctatgaatg
     1141 cagaattcca atcaaaagta gaagaaattt tgaaaaggaa ttatcaaaca ttgatcaaca
     1201 acggcaaagc acagtattcg cctggtgctt atgcagtggc tatgaatcct cagacaggag
     1261 aagtgctagc aatgactggt ttcagtcatg aacaaggttc caaagaaatc accgagaatg
     1321 ctttaggcac gattactagc gcctttgatc cagggtctgt agtcaaggct ggtactttga
     1381 cagcaggctg ggcaagtaac gcgatcagcg gaaatcaagt tttgattgat gagccgattc
     1441 gtctgcaagg tgcttcagaa aaaagctctg tctttaatcg aagcggacaa gttgctcttg
     1501 atgcagtcaa agcatcggaa ttgtcttcta atacgtatat gatcaaagtg gcgttaaaga
     1561 tgttaggact agactataca cctggaatgg gactacctag tttagatgaa gaagctaaag
     1621 cttatcagca attgagagac tctttcaaag agtttggtct tggtacaacg actgggatcg
     1681 atttgccgaa tgaatctcct gggatctcac gttctgttga ttatatgaag aagttcaatg
     1741 cggataatgg caaagaatgg tatgctccag gtaactttac cgatttggca tttggacagt
     1801 ttgacacata tacaccaatc caattagctc aatatgcttc aacagtcgct aatggcggga
     1861 aacgagtaca gccgcaccta gtcaaagcga tctatggcaa tgacgaaaat ggaaacttgg
     1921 gtgaagtgaa gaaagaaatt ggcacaacag tagaaaatac ggtcaatatt tctgcagaaa
     1981 atatggcgat cctccgtgaa ggattccacc aagttgtcca tggtaccgat ccttacacaa
     2041 cagccaaacc attagccagt gcgaaaatgg acctttccgc aaaaacaggg actgcagaaa
     2101 cggttgcgga aggtcatcca gatattgcga cagtcaatag taatatcgtg gcatacggac
     2161 caacagacaa tccggaaatt gccatcagtg ttgtcttgcc gaacttatta gacgaacaag
     2221 accacataaa cttgacgatt gctaaagaaa taatggacgc gtattatgat atgttcatgg
     2281 caaaataaaa aagaggtcgt gaaaaagccg cttagtttcg agtatgaaga aaaattttgt
     2341 gaaaatagct tctcacattt ttgcttaaat ttgacttcat accgagaaac tggcttttga
     2401 acaccgttta ctcggcaaaa aaggttgtga caaaaattg
//
LOCUS       DACGDM010000179         2433 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.187, whole genome shotgun sequence.
ACCESSION   DACGDM010000179 DACGDM010000000
VERSION     DACGDM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.187"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(1..286)
                     /locus_tag="IXR05_002869"
                     /pseudo
     CDS             complement(1..286)
                     /locus_tag="IXR05_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(608..829)
                     /locus_tag="IXR05_002870"
     CDS             complement(608..829)
                     /locus_tag="IXR05_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261299.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(927..1172)
                     /locus_tag="IXR05_002871"
     CDS             complement(927..1172)
                     /locus_tag="IXR05_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261300.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1412..2026
                     /locus_tag="IXR05_002872"
                     /pseudo
     CDS             1412..2026
                     /locus_tag="IXR05_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT          816 a          430 c          348 g          839 t
ORIGIN      
        1 ccgcatcaat tgcacgataa agataatgcc aacgtccctt aattttgata taggtttcgt
       61 ccattttcca tgaatagaag gattgtctat ttttcttctt ccaaagataa tagaggactt
      121 tgctgtactc ttatacccaa cgataaatcg tagtatgaca aacatttatt ccacgatcat
      181 ataacaattc ctgaacttca cgatagctta gattgtaacg caggtagtaa ccaacagcga
      241 caataatgac gtcttttttg aattgtttgc ctttaaaatg attcattact ctgtcctctc
      301 tgtctttttt ctcaatttta cactaaaata gattttttgg aaaactttgc aacagaaccg
      361 tttttactat atacttcttc ccagaacttg tccgtctcct tcaaattatc tctacctctc
      421 gagttcattg ggtggtttgc ccatttatta aacatggaat cacctttctc atactcatat
      481 atttatgtcc tatttcaatt atatttatat atgcttaaat aaatttgtat cctgaaattt
      541 attgtaatat gaagctgtat tttacatata gtaaccaaag agttaataaa ataaaaagag
      601 cgaaccatta tagatcagct cttttttcat tgctgttttt aatcttatct agaatcactt
      661 caaatgtttc aaaggtattt acatctaact gacataacca aagcaagtac ttcttttctt
      721 tgtaagtcca atcaatatta cggtaagagg acattagatt atggtacctt gctctttgtt
      781 caactgaagc caattcccag cgtttttcaa atattttttc ttcttccatt attgatccct
      841 cgcaagacgc tacctcaaac ttaaataatg ggcagcgaaa gtctaattcc ttagatctaa
      901 gtatagcaaa caaatatgaa aaaaacttag aaggtagtaa aagttcttcc gtcttttgct
      961 ttgcttctat tcttaatgtg tttcgttatc ggtgccctac aaagattttc attaattaca
     1021 cactcattta ttgttgtgta ttttctgaca tttctctctt gatcaattat tttaattcca
     1081 tgggcatcct gatagttcat aggagaggag cggctatcag aaatagttgc acctatctct
     1141 tgaacttctt ttacaacttc tggaaaatcc atccatcctg cttcagctgt caaaagtaat
     1201 aatctataat atttatcttt ccttttcaat ctaagaaatc gtcaccccat tctttttctt
     1261 ctattataaa ctatttaact tttagaattc aaaaaccgtt tgtctattta gagtttaccc
     1321 taaatagaca aaaatataac attgaaaaat ttagagttct aacgtatgat tagggtgtat
     1381 tataaacgtt atagaaaagt agggaataaa tttgaaaatt gcttatatta gagtttcatc
     1441 catcgatcaa aatgaacaac gtcaaattga agaaatgaaa aagtttggcg ctgaaaaaat
     1501 ttttatcgaa aaacaatctg gagcgacgat tagtcatcgg ccgattttcc aggaagcttt
     1561 agattttgtc agagagcaag atatttttat tgtagaagcc attgatcgac ttggacgcaa
     1621 ttatgacgag attatcgatt cagtgaatta tctaaagaag aagaatgtgc gacttattat
     1681 caccagttta ccgatcatgg ctgaagcaat tggaaatcct ctcctagata aattcatcaa
     1741 agacttaatc atttaaatct cagccatgat tgctgaacaa gaacgtactg aatcgaaacg
     1801 acgccaggca caaggaatta aaatcgctaa agcaaacggc gtctataaag gtcgtcctaa
     1861 gttatacagt gcagacacca aagatcctca acgtcgcctt gtctatagga gtatcgttca
     1921 ggatcttgag aatggggttg ctatctcaaa gattgcaaca gactacaatg tgactaggca
     1981 aacaatttac cgaataaaaa aagaaatcga ccaactaatt gtatgatttc ttttttgaat
     2041 cacgtaatta ttaattagct ttgtcatcaa tacagacaat cattttagat tcatctagct
     2101 aagttgatta catttatgtt aaaaagaatt tagttaacat aaatataatt gatgcataaa
     2161 tcgtccttat ttaaaggcat ttaacattga caacttagta taatgtatct tatgtaaact
     2221 aataagattt gaattttatt ttatacacac tcgataatag atcaatttta tggtcccccg
     2281 catttacgat tgcacaagag aaacataaag tcgacctatt agcatttctt ttcaattcaa
     2341 acattaaaaa agtttatacc tctgctacta aaaaatgaaa ttatctattt aaaatttaaa
     2401 acggtaaatc tgattcatcc aaattggaaa atg
//
LOCUS       DACGDM010000180         2407 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.188, whole genome shotgun sequence.
ACCESSION   DACGDM010000180 DACGDM010000000
VERSION     DACGDM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.188"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            5..1150
                     /locus_tag="IXR05_002873"
     CDS             5..1150
                     /locus_tag="IXR05_002873"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAQ4261301.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="IXR05_002874"
     CDS             1321..1779
                     /locus_tag="IXR05_002874"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAQ4261302.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..>2407
                     /locus_tag="IXR05_002875"
     CDS             1938..>2407
                     /locus_tag="IXR05_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAQ4261303.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          802 a          452 c          455 g          698 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgttagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttcttta
//
LOCUS       DACGDM010000181         2400 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.189, whole genome shotgun sequence.
ACCESSION   DACGDM010000181 DACGDM010000000
VERSION     DACGDM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.189"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            207..2069
                     /locus_tag="IXR05_002876"
     CDS             207..2069
                     /locus_tag="IXR05_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4261304.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="IXR05_002877"
     CDS             2069..>2400
                     /locus_tag="IXR05_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4261305.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DACGDM010000182         2369 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.190, whole genome shotgun sequence.
ACCESSION   DACGDM010000182 DACGDM010000000
VERSION     DACGDM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.190"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(165..2249)
                     /gene="cadA"
                     /locus_tag="IXR05_002878"
     CDS             complement(165..2249)
                     /gene="cadA"
                     /locus_tag="IXR05_002878"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4261306.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
BASE COUNT          687 a          526 c          362 g          794 t
ORIGIN      
        1 tttttccatc aaaaaaataa gttattttct tttatttcat tgaccttatt gaatttcaag
       61 ctattttgaa ttttctgcaa aattaaaaac attagttatt ttataatcct atctattttc
      121 tttacatttt tcattaagaa aaggatataa aaaaaagagg acgttcattc gtcctctttt
      181 tttacatgca agcttcgcat ggcattcaaa acagctaata ctgtcacccc aacatctgca
      241 aatactgcat ctcccattga tgcaaaacca aaagcaccta aggcaagtac caaaattttt
      301 atcccaatag caaagacaat gttttgtttg acgattttca atgttttctt tgctaaatgg
      361 attgcttctg caatcttcga tggttgatca ttcatgatga ctacatctgc tgcttcaatt
      421 gcagcatcgc ttcccaatcc acccattgcg attcctacat ctgctcttgc tagcaccggt
      481 gcatcgttga ttccatctcc gacaaatgcg gtctttttat tgtttctttg taagatttcc
      541 tctaaccgct gcactttatc ttcaggaagc aattcgctat atatcttgtc cacgcctact
      601 tgcttcccga tatgatcagc aatttttttc gagtcgcccg tcaacataac tgtgttcttc
      661 acaccagcct gttttaattg aaccaatgcg tctacggcat cttctttcaa ggtatctgca
      721 ataacaagat aaccactgta actttgatcg atcgctagat aaagcaatgt accgatttct
      781 tgacttaaag gaaaagagat ttcaaatctt tccatcaatt tgtgattacc tgctaatact
      841 tgtttgccat caacttcagc taagatccct tcacctgcaa attcctggat attagttgtt
      901 ggtaaaagcg gacctgcgta gccttctaaa acagattgag caatcggatg tgtagaaaac
      961 tgttctgcac tcgcaatata ttgcatgaat ttctttggat cgatttttgt atcgatcgtc
     1021 tggatcgaaa agtcaccttt cgttaatgtg ccggttttat cgaataccac tgtctcggtt
     1081 tgcgcaagca actccaagta atttgaacct tttactaata caccgatttt acttgcgcct
     1141 ccgataccgc caaagaaact aagtggcacg gaaatcacta atgcacatgg acatgagatc
     1201 actaaaaatg tcaatgctcg atagatccat tcagaaaacg ccgctccaga aacaacaagt
     1261 ggaggtaaaa cagctaataa aacggccaat cctacaacga ctggtgtgta atagcgcgcg
     1321 aatttagtaa tgaaattttc agctggtgct tttttactgc tggcattttc tactaattct
     1381 aataatttgc tgatagtaga attttcataa gatttttcta cttgaactaa aaatggttta
     1441 tttttattga taaatccgct taatactgtt tcaccaacat atacagattt agggactgat
     1501 tctcctgtaa gtgctgacgt atcgactaat gattctcctt cgatgatcgt tccatctaac
     1561 ggtacacgtt caccaggctt cacaagtaca aactgaccga tctgcacgtc ttcagggttc
     1621 acggtcatca atccttccgt cgtctgcacg tgagctgttt ctggacggat cgccatcaat
     1681 tcgcgaatcg attttcttga atgactgact gccaatcctt ggaaatactc gccgatttga
     1741 taaaatagca tcactgctac ggcttctgga tattcaccga tcaacatagc gccaatcgta
     1801 gcaacagaca taagaaaatt ctcatcaaag atttttcctt tgacgatatt catcactgcc
     1861 ttcttcacta catcatatcc tatcagcaga taaatcaata aataccctat caagcgaatt
     1921 ggttcattaa aatcaaataa tagcaataaa gcgatacctg caagggaaaa taaaatccgg
     1981 aacagcgtat ttctctcttt ttcatttcca tgttcagata ctttttcctt atctatttct
     2041 gttactttga catctggttc taattccttc actacttttt ttgtttcttg ttcaatcgta
     2101 gccaaatgat cttcctctgc gtcaatcgtt agttttccag aagtgaagtt taccgttgct
     2161 tccttgactc cattgatctt ctgaactcct ttttcgattt tcattgcaca gttcgcacaa
     2221 tctaaacctt ctaatctgta acttttcatt ttaatgacct cctcgcctca acatatgaac
     2281 atctcttcat aactaattat aaatgaatgg ttattcatat gtcaaggtat ccgaaagaaa
     2341 aaatgaaaaa catctgcatc ggaaaattt
//
LOCUS       DACGDM010000183         2232 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.191, whole genome shotgun sequence.
ACCESSION   DACGDM010000183 DACGDM010000000
VERSION     DACGDM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.191"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..544
                     /locus_tag="IXR05_002879"
     CDS             <1..544
                     /locus_tag="IXR05_002879"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4261307.1"
                     /translation="ISKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLH
                     TKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNK
                     IRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
     gene            complement(900..1472)
                     /locus_tag="IXR05_002880"
     CDS             complement(900..1472)
                     /locus_tag="IXR05_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261308.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1488..2093)
                     /locus_tag="IXR05_002881"
     CDS             complement(1488..2093)
                     /locus_tag="IXR05_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAQ4261309.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          700 a          454 c          338 g          740 t
ORIGIN      
        1 catttcaaaa gagaatctct taaatcagga cttttctact gaaacgatct gtgagaaatg
       61 ggcagctgac attacgtaca ttcctactaa gaaaaatggt tggtgttact tatcttcaat
      121 catggattta cacacgaaaa gaattattag ttatacattt tcaaaacgaa tgactgtgga
      181 ttgtgtcatt caaacattga ataaagcaaa aatacattat cacattccag aaggaatgat
      241 tctacacact gacttgggca gccaatacac agcaagagaa gtggaacaat ggcttaaaac
      301 caacaaaata aggcattctt atagtagaaa aggaacacct tatgataatg ctggaatcga
      361 atctttccat gcctcattga aaaaagaaga agtctacacg actagctact cagattttga
      421 agaagcaaat cgagcgctat ttagctacat tgaaggattt tataaccgaa atcgaatcca
      481 tagctcgatt cactatctaa ccccacagga atttgaagaa ttagcaaaag aaaaaatggc
      541 ttaaccgtct ctactaaaga caatcaacac cgtagggata tggagataaa atcaatagag
      601 tcaatagatt atttatcgat aataacacta aaaaagccac gttcctaaac gtgacttacg
      661 ctgaacgata tgtgttgttt ggtagacgaa caaatcgttc attataaata tatgatggta
      721 tcctaatata gtaagcgtgg ctagcatacc tttaattact ttacctttta cagttaccat
      781 acacattttt tgagcagaaa tcaagtaaat aaaaaaatat tatatttcac aacatgctaa
      841 tagactcata tctagaacgc attaagtatt tacctgtctg gttcgctgag acttcttttt
      901 taactttctt caattttctt ctttattcta aaaagcgtac tgcgactgaa accggttata
      961 gcttcaactt ccttatacga tttacctgaa gtaagcagtt catatgcgtg cctcttcttc
     1021 ggtgtgattg ttgctttcgg acgtccttct ctgaaattag gattattctt tcttgcaaac
     1081 atttttcctt cttgggtacg ttccacaatc atatcacgtt ccatttctgc tacactcaac
     1141 aacgtccgtg tcaccattcg ccccatggac gtattttcaa tcgttcctag attcaaaacc
     1201 ttgatcgtta cgttatcatc gagtaaaggt tcaatgatct ctaatgcttc tctcgtgtta
     1261 cgagcaaatc gatcaagctt cgtaacaact atttcatctc caggcttcag accagccaac
     1321 agctgattga attttggccg atcccgtttt gtacccgtaa atttttctga aaaaatattc
     1381 ttcttctcta cgcagttctc aagcaactgt tgaatttgtt cttttgtact ttgagaagcg
     1441 gttgagacac gtgcatatcc atatttcgtc atttggtcca cctactttta caaatcatct
     1501 atcgtatact cagaataccc ttcatagaaa tagctgacat cgattccttt catatataac
     1561 tcgcgatcgt caattttatc agtcagagca ttggaaatta gatagcgtat ttccaaatcg
     1621 tttatgggac ttcgctccat tgcagaaaga tagtctgctt tatcgattaa gttccaatct
     1681 acaacttttt gcaattcttc ctttaaaatg agatccagcc aaattctagt acttcggcca
     1741 tttccttctc gaaatgggtg agcgatattc atctccacat atttcttgat aatctcttca
     1801 aaagaagttt gtggcatctg atcaatatgc tgtaacgaat gttctaaata cataactggt
     1861 gcaaatcgaa aatttccttt tgcaatattg accgatcgga tttttccggc aaaatcgtaa
     1921 atatccgaaa atagaaattc atgaatttca gataaacctt taaatgtacc aacttcgatt
     1981 tcatttattt ttccacaatc gtacaattct ttcgcttttt gtttactgag tttttcttca
     2041 accttagcca actcaacttg attggttaat cccaatttat tctctaaaat catgcgaaat
     2101 ctccttaact ttatgacata agtttatgaa acactctcaa ccccattata tcgcgatttt
     2161 gtttatgtgt caaaaactat taagtttctg acccccgata gatttttcaa gtgtctctat
     2221 tttgcacagt ct
//
LOCUS       DACGDM010000184         2220 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.192, whole genome shotgun sequence.
ACCESSION   DACGDM010000184 DACGDM010000000
VERSION     DACGDM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.192"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(205..1104)
                     /locus_tag="IXR05_002882"
     CDS             complement(205..1104)
                     /locus_tag="IXR05_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAQ4261310.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(1114..1470)
                     /locus_tag="IXR05_002883"
     CDS             complement(1114..1470)
                     /locus_tag="IXR05_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4261311.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1825..2121
                     /locus_tag="IXR05_002884"
     CDS             1825..2121
                     /locus_tag="IXR05_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAQ4261312.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
BASE COUNT          692 a          422 c          380 g          726 t
ORIGIN      
        1 tatatttttt tttgtgatta tcgttcaaaa aaagaataca cgcttgcatc tagtactctg
       61 cgagttacaa atcatccgat caaataaaca ttcgctgatt attttccgca aaaaaagcag
      121 catatccacg ataaatggat ctactgctct tacttatcct tatgttttac aaggtatttt
      181 cttttacaca ttactaatgc tgtctcaata cggaacgatt gtcatcgctt gttcaaattc
      241 ctcttgcaaa tgttgtgttt gataggcctg aaaagctggg tgatgggcac gcaagaggac
      301 acgtaatttc ataggatcat agctgtctag caactgttct ttcaagacaa aatctcgggt
      361 cagctgccat tcataataat aaccaaaagg tctgcagctg taaatcgtgt gaccgatgga
      421 tttatcttca aagcgacgat gcgtatggcc aaaaactact tgtttgatat ttgaataacg
      481 gtcaagtaat tctccgaatg attctgatcc taaaaatgca tttaatttgt tccaacgctc
      541 ataaggagca gattgataca tgataaatgc ccgtttagga acgaaatgag tggataaaat
      601 cacctcaagt ttttttgctt ccagctggtc tagcaaattt tttgcagctg caagcatttc
      661 tgcattgacc tcgagatctg ttttcccacg ctggatgaac cgatcatacc aatacaaacg
      721 cttcattcgt acgattgcct cgtaatcttt caattcggaa aactgatagt cgtaccagcc
      781 attcatccct aaaagaacgg tctgctcatt taaagcaata taccgttcat ttaaaaaatg
      841 tgggtctgga aaatggtcca tcatctgttc attgggcaca tctgccaact cgtgattgcc
      901 gaaatgaaat gtcgtagata atcctttatt gacgaaaaat tcgacaacag ctaggcaacg
      961 gtctacttta ttagccgtat ctccggctag atgaagccga gtgatcttgt gcttttgcaa
     1021 aacttgccaa agctgcatca gctctgattc gccgaattta ttgatgtcca catgtaggtc
     1081 gctgatgatc gccaattttc ccattttatc cctctagtct tttcgaacaa cttgcaagtt
     1141 gccttttctc aagccgcttg gtccttttaa ttgtaaacta ttataagttg gttctaaagc
     1201 aagtgtggat ggatcatcca tgtaaagtat tgcactgtct ttgattttga ttggtccaac
     1261 tggtgtatca gccactacag aataaagact tagatctgtt tgtgtatctt ttttgacaat
     1321 gatcaatcga aatgccgtat ccaattggca actgacttgg ctttctgcaa atggaccgtc
     1381 accgttttcg atatctaata aaagttgatc gtctgcttct aatttattct tcaatacttc
     1441 ttgtgcttct tttgtcactt ctaatttcat ctgtatcacc tcatgtcata gaataatcac
     1501 tttattcatc agatgcaact aatttgtctg gttctgactg ttctcaattt attggaaagt
     1561 aagtcattcg tttattatga tttctcttat cacaaaagag acaactttcc cttttcttcg
     1621 ttcagtttct tgaacggaaa aagacccaaa aagcaacctg ttatttgttt aaccttattc
     1681 ctttcttaaa taacaaaaaa tactataaaa aataaaaaac ctttaacaac tattggaaaa
     1741 agaattactt tttgttcacg gattattaac aactcttcgg tagagtaaac ttatcaaata
     1801 aaagacttct ttggaggaat cactatgaag gaatatataa aaaacatcta ttttatcgaa
     1861 gaaacacaaa atatcgaggg ttcttatatt gaagtaaaaa cactctttgt caatgaagat
     1921 aaaaccaaag cattggatat ttataaaaaa ttagcttcaa aaaaaacgaa tagttttgga
     1981 ttgatattaa gcgagtataa aatcaaagca gaagagagtt atttctatca attattaaaa
     2041 cggtggagta agcttcccgc cgatttttat cgaaaaatgc agatcatcaa ctatcaaccg
     2101 cttgctgaga cacatgccta aatagaggtt gtgaaatcag tgctttgagc taataccgaa
     2161 ggtcagctga ttgaacattg tttagaagag attgtgacaa ctgcgatttg ctttgagtaa
//
LOCUS       DACGDM010000185         2215 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.193, whole genome shotgun sequence.
ACCESSION   DACGDM010000185 DACGDM010000000
VERSION     DACGDM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.193"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..322
                     /locus_tag="IXR05_002885"
     CDS             <1..322
                     /locus_tag="IXR05_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4261313.1"
                     /translation="YKAIIPENLDEVKLYLWEDNGEIVGFSGVSAEELVMLFLDPDFI
                     GKRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLDGFGKPYPITH
                     LVKK"
     gene            736..1554
                     /locus_tag="IXR05_002886"
     CDS             736..1554
                     /locus_tag="IXR05_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4261314.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1627..1986)
                     /locus_tag="IXR05_002887"
     CDS             complement(1627..1986)
                     /locus_tag="IXR05_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4261315.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          746 a          319 c          414 g          736 t
ORIGIN      
        1 ttataaagca atcattcctg agaacttaga tgaggttaaa ctttatttat gggaagataa
       61 cggagaaatt gtcggtttta gtggtgtaag tgcagaagaa ttagttatgc tatttcttga
      121 tccagatttt attggtaagc gatatggtag tcaaatatta attgagctga ttgaaactga
      181 agatataaaa agaattgatg ttaatagtca aaataaatat gcaaaacatt tttatttaag
      241 ccatggattt gaaattgaat ctgaagaaga cttagatggt tttggtaaac cataccctat
      301 aacgcattta gtaaaaaaat aattcatgaa tggtttatta cctgattgaa catgaataaa
      361 agtaatattt ttattttgat ggcctatttc taggttatga attatccaga tcaaatttgt
      421 gtattacatt cagtaataag gtgcttatct taggatcaac ttatgatact agctgaccaa
      481 ggatgtacca gttatagaaa atcagttaaa gtaaaaatga taaaaatctt atgtcaacac
      541 tgatttaggc tgacctgtgg gttaggagaa agacaggtcg gtagctttta atacaaaaaa
      601 tggcttgtat gtatctagat agttaactga aattagaaat gttcttattt ttaacggagt
      661 aagaaaaata ggctgcttta ggtctgaata ctttttcaat ataatgaaga tatcaaaggc
      721 gacaggagtg tttttatgaa taagaatcct cataatctaa agttggtagc agtagatatg
      781 gatggaacat ttgctcgtac tgattacaca tacgatatcc caaggttcaa ggctgtttta
      841 tcgcgaatga aagctgttga ttgtcaattt gttgttgcaa gtggaaatca atactaccaa
      901 ttgagatcgt tatttccaaa ttattatgat gaattaagtt ttgttgctga aaatggtgct
      961 tttgttaaag ataaaacaga ggtactattt tcagccgata tgcctagaaa agcgatcgag
     1021 gtggtccttg atttatgtaa agactatcct gaagtaaaaa atgtgatgtg tggtctgaat
     1081 agtgcctact gtgaaagagg aaaggtgagt caagcatttt ttgatctaac caatatctat
     1141 taccatagat tagaatgggt agctgatttt gcagaagttc aagataaaat tttaaaattt
     1201 gctccgacta tgcctgttga aaaaaccgaa ttttacgttg aattgttccg tgaaaaatta
     1261 gccgggctat tagtacctac cagtagtggt catggttctg tagacttgat tctttctgag
     1321 tgccataaaa ctttcggctt gaaaatgtta gttgagcgct tggggattaa tcctgaccag
     1381 tgcgttgctt ttggagatgg gggcaatgac attgagatgt tggagtattg tggtctgagt
     1441 tatgaaatgg ataatgcaac ggaagctgtt aagcaagttg ctaagcatca atgtccttca
     1501 aatgacgaag acggtgtttt agtgacgctc gatcgattgt tccctaacac gtaaacacta
     1561 ggtaattcat caaaaaacct cgatataaga aatattcgag gttttaaaac tatatttaga
     1621 acagatttac gaagcgtctg atgagtcaaa atagacttgg acattgctat ctaaaatacc
     1681 actttcattc tttaaacgaa ttgtttgatt tgatggagtt acctctaata ctaaatgccc
     1741 attaataaag gtagtatcgt attcagatgt tttaactgtt gcttcttcgc aaggtattgt
     1801 taaatcatat gctggaatat aatgttgtgt ggaaactaat aaaaaatgat caccaatcat
     1861 acagcatccc tctgctgaag aaaattgatt agagccatca tttaaagtta acaagaatcc
     1921 atcctttaaa cgaggtactt gcttaaatac ttctggttgt acttctaaaa ataaattatc
     1981 gctcattttc acgaccacca tcgacttcca cagttgaaat tgacatttta tttaacacac
     2041 ctattccccc ttaactataa ctcaattcta tataaaaaat attctattct caaataattg
     2101 aacttttcaa atcgccaatt tacttcggct ttatcagagc tcattcatat caagagcgat
     2161 taacgctgta aaaattaaac cgaagatctg ataaattttc tctattttct acaat
//
LOCUS       DACGDM010000186         2159 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.194, whole genome shotgun sequence.
ACCESSION   DACGDM010000186 DACGDM010000000
VERSION     DACGDM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.194"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..914)
                     /locus_tag="IXR05_002888"
     CDS             complement(<1..914)
                     /locus_tag="IXR05_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAQ4261316.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="IXR05_002889"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="IXR05_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAQ4261317.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT          733 a          381 c          417 g          628 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaagaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaa
//
LOCUS       DACGDM010000187         2149 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.195, whole genome shotgun sequence.
ACCESSION   DACGDM010000187 DACGDM010000000
VERSION     DACGDM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.195"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            363..889
                     /locus_tag="IXR05_002890"
                     /pseudo
     CDS             363..889
                     /locus_tag="IXR05_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1044..1619
                     /locus_tag="IXR05_002891"
     CDS             1044..1619
                     /locus_tag="IXR05_002891"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAQ4261318.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1662..1859)
                     /locus_tag="IXR05_002892"
     CDS             complement(1662..1859)
                     /locus_tag="IXR05_002892"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261319.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            1846..2028
                     /locus_tag="IXR05_002893"
                     /pseudo
     CDS             1846..2028
                     /locus_tag="IXR05_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
BASE COUNT          759 a          340 c          404 g          646 t
ORIGIN      
        1 tacaagacaa agtatagcaa gcaaaattct tctccacttc cagaattttt tattttcatt
       61 tttagaaaag tgaaaaaact gacaacaaaa gcttgtttct ttcactctat taatatcttt
      121 agtgaaaaag ctcgttttat atcgtattct tccagcgaat gtacttctca taagtccaaa
      181 aaaagctgcg aaaaagaaag tacctcggta cctacttttt cgtagctgca cataacttga
      241 gcaagtatta atcgaagata cttttgttga gagtgtaaaa tattttgtgt aaatagaaaa
      301 aaggaagtcc cttctgtaga atagagttac cacaacacat tcacagaaaa gaggacttcc
      361 atatgaacga ttttactaca gaaatcctaa agactctagc gaacaaaggc gatttgaatg
      421 gattattccg tgtccatttg gaaaaagctg tcaatacgct tctcaaaacg gagttaacgg
      481 ctttcctcga ttacgaaaag tacgatcgca ttggttttaa cacgggtaat tctcgtaacg
      541 gctcctatga ccgtacggtc aagaccgagt atggggaact tcatctccag attccgcgcg
      601 accgcaatgg cgagttcaag caacagactg ttcctgctta tagacggacg aatgacacat
      661 tagaggagac cgtcattcac ctcttccgaa aaggtattac catgtcggaa atcgcagact
      721 tgattgagaa aatgtatggg catcactaca cgccccaaac catgtccaac atgactaaag
      781 tgctgactga agaagtaaat gcatttaaag ttagaactct aaatgataag tatgtcgcta
      841 ttttcatgat tccttcagtt tttcagatga tataccactc aaaaaacaat atgagagatg
      901 ttcaggaata ccatctctaa tggcttataa attggtttta gggatagtag atgttataga
      961 catatcaagg aataaacgag cagctgcata aaagcagatg gaattaagga ataattgaat
     1021 tgtaaaagaa gggaataaat ttaatggcac aattatttta cagatatgga acaatgaata
     1081 gtggaaagag tattgagcta ctgaaagtgg ctcataatta tgaagaacaa gggaagagag
     1141 ttatcataat gacaagcgca atagatactc gatcaggatt tggaaaagtt gagagtcgta
     1201 taggtgtttc gaaaccagct attgcaatta cttctgaaat ggatgtgtac ggagaattag
     1261 tggagattat tgatcagtac ggaaaagttg attgtatttt ggtcgatgag tctcaatttt
     1321 taagtagaga gaatattatt gatctatcac ttatcgtaat gaatgaggaa gtaccagtaa
     1381 tttgctatgg attgaagaat gattttcaaa ataatctctt caagggatcc gaagcattat
     1441 tgacatttgc tgataaaatt gaggaaatta aaactatttg ccatttttgc aataaaaagg
     1501 ctgtaatgaa tgctcgtatt gttgatggta ttccagttta ttcaggtgaa cagattgtag
     1561 taggaggtaa tgaagattac ctttcggtat gtcgcaacca ctactacaac gaagattgaa
     1621 ataaaaaacg tgtaatcaaa taattgatta cacgtttttt attattctgt taaaggttga
     1681 ggatcagaaa tttttaggta tctataatcc tcacctaaaa atccgttaaa acgaagtaaa
     1741 acatcatgac catttaaatc agttggaact aaaattggaa ttaatttatc aacagtagtt
     1801 ttgttgtaaa gttcaaaagt gttctccatt ccttctggtt ctacaatcga atctttcaat
     1861 aaacaaatca agaaatacag ccgcagaaaa gagcagtttc aaaatgaaga atcactagag
     1921 cgtttcctag tatccatctt tgatacatac aatcaaaaat tcttaaatag aagccataaa
     1981 ggcttccaac aagtgacgga tacattagct tcaatgttta ctgagtaacc cattattttg
     2041 cagaaggacg agttatttac acaaaattat tgacgctccc tgtttggagt ggtaaaaaga
     2101 ttgagaaatt gtttcattag ctattacgat tattattgta atatatttt
//
LOCUS       DACGDM010000188         2102 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.196, whole genome shotgun sequence.
ACCESSION   DACGDM010000188 DACGDM010000000
VERSION     DACGDM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.196"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            169..1539
                     /locus_tag="IXR05_002894"
     CDS             169..1539
                     /locus_tag="IXR05_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HAQ4261320.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1560..1844
                     /locus_tag="IXR05_002895"
     CDS             1560..1844
                     /locus_tag="IXR05_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261321.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          730 a          308 c          444 g          620 t
ORIGIN      
        1 ttgatttacc aacatgttta gacattttcc tctaggaaaa aattaactag caccacgcgt
       61 attgtttata ttaaattaga tgaccgtgat aatgcacagc aaatttttga aagtatcaat
      121 tctaccggtg aaagattgac tgcctcggat ttgattcgaa acttcatcat gatggataaa
      181 tctaatgaag agcagactac gctttatact aaatattggc gtaggttgga agaagtcttt
      241 gataattcta aaggaatgga agactttttc agatactacc ttgctgcaat aactggggag
      301 tattcagcaa agcatattct ttatcaagca ttcaaagact attggcataa agagcgcgat
      361 gtatcaagtg atgccgaatt gctccaaaaa ttagtgcgat atgctggtta ttttgcgaga
      421 ctttactata acaaacctga aggaaaatac tcagaagtat tgagcgattt ccaaagtatg
      481 gaaagtatga tgcctgcacc ttttgttttg ggattatctg aatggtacta tcatgaccaa
      541 tttatcactg aagaccaata tattgatgcg attaaggtag tgaatgatta tcagcttagg
      601 agatatttta atggggatga tacaagcaga gtgtcaaaag catttccttc atatttgaaa
      661 agtgttagga agtacgctaa agctaatgga tatgaaaata tcgttgatat tgtaatttat
      721 gttcttgtta ctagaaatca atcaaataat atggcacttc catctgacaa ggcattgaaa
      781 tctaatctat tgaatgccaa tgcttatgcg atgagattgg cccgttggtt acttgaaaaa
      841 atagagaatc gagaaaattc agcaacactt gatatgagta acttgtccat tgaacacatc
      901 atgccacaga ctagtacttc atattgggaa gagaaggctg gtacatcggg ggaagaatac
      961 acaggattag taaataccat tggtaattta acactcgtta caaatcctga taattcggcc
     1021 gcgggaaata aagactttga gaccaaaaag aaaatctttg aagataccct tcatattcgt
     1081 atgaataaag atttgtacga attgactgag tggacatcat cggatatttc tgccagaagt
     1141 gaagctctaa tcaatgaact gattactatg tatccctatt tgagatcgtc gggcgactat
     1201 gaacacgatg ggaataggga aattttctta gaggcgcaag gaataaaagc aactgggtat
     1261 ttgaacgaag acgagaccgt gattatacat tcaggttcag aaatttattc taagattaaa
     1321 gatattgcat ctgattcgct agatgaaact cgccaagagc tgttggataa tggaatcatt
     1381 gaagaaacaa ttgggggact acaatttgtt caagattaca ctgcctcatc tgtttcgaat
     1441 gcagcagctc tgctattagg gggtagccgg aatggttggg actactggaa atatgataac
     1501 ggaataagta ttaatgattc gctaagaaat aagaaataga gcatagaggt ggtgttaggt
     1561 tggataagaa caaactaaga tatgcaattc ttaaattgcg tgatgaaaaa aagaatcctt
     1621 ttattgagct taaagggcaa gttccagaag aagatatttt agaacaaact aaatttcttt
     1681 cgcgcaatgg cttactagaa tccatggttt gggcggataa cactgttcat atctggggga
     1741 gtgtttctct ggaaggggaa aaatatttag ttgaaaactc aggtcttgct aaggcgtatg
     1801 cattggcaaa agaagttaaa aattggattc cattttgggg ctaagataag tttttaaacg
     1861 gagaaggtag caaatcataa ttggtttgtt gccttttttg attgcccaaa aagaaaaatg
     1921 acaaagtata gagataaatg acatagtaca cgggaaaaat gacattgtat caccgacaac
     1981 gtctaaatag atgttgatat atatacgttc cgtacaaata attataaaaa tttaaatgat
     2041 ttgagtagaa gtatcagtga atatctcaag gggaatagct atctcaagat tcgattttca
     2101 ca
//
LOCUS       DACGDM010000189         2084 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.197, whole genome shotgun sequence.
ACCESSION   DACGDM010000189 DACGDM010000000
VERSION     DACGDM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.197"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(575..940)
                     /locus_tag="IXR05_002896"
     CDS             complement(575..940)
                     /locus_tag="IXR05_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261322.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1016..1261)
                     /locus_tag="IXR05_002897"
     CDS             complement(1016..1261)
                     /locus_tag="IXR05_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261323.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1331..1585)
                     /locus_tag="IXR05_002898"
     CDS             complement(1331..1585)
                     /locus_tag="IXR05_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261324.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1749..2072)
                     /locus_tag="IXR05_002899"
     CDS             complement(1749..2072)
                     /locus_tag="IXR05_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261325.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT          772 a          358 c          369 g          585 t
ORIGIN      
        1 tttagaaatt attaattttc gtctgaaaac aaaaaaagaa agcgttatta ttttagtcta
       61 ttttcagggg gggaacctta tgataaaaaa actattttta ctatcaatat taacgctagc
      121 aatggcaggt tgttctgact ctggcttagc aactgaactg atcacaaaat caactgaagc
      181 cacgacagag gagttaaaat gtggaaacga tcacagtgac tacagaggct taaatcgacg
      241 atgcatggga atattaggca gaagcaattg taagcatcga tgtagtaatc gaagaaggtg
      301 tagaagaagc aacagaaaaa tcaaaagaaa gatcaaaaga agcaatctgt gctgtgcatc
      361 gtatacagac gtcgaagatg cggtactttt aaaccacgtc aggagatgtt catttatgtc
      421 tagggaagtt ggcgatgaac caaaactaga gtacgctttt agttttgcac gtgaggatga
      481 agataaccct aaaacttacg acattttagc ttgatctaag atggttaaag ctttttaatg
      541 aagtaagagg agatagaagg cttttctagt tatattaggt aagataaatt cctttttgct
      601 ccaaatttgc taaacattct gctagataaa cttcatcgtg ttccggataa atcggcacgt
      661 tgcgctctac agtaggtaaa tcaaaaaatg cttcgcatga tttgccacga tacataggat
      721 ttttccactc tggtgctggg ctgtaaccac gtttttccat ttcatccatg acaagctgat
      781 gatattggaa taatctataa ggagaatagt gaaaaacata atccacagta gcatgtttct
      841 ttccccagcc atttcctctt aatgcacagc attcccgatg ttgtcctaaa agctgttgac
      901 gaggaagctt tgaaatcaat ttttcatgcc ataatcgcat agaaatgtct cctttatata
      961 tagattgtta accttagacg ttaaatgaaa aaaccagcac caaggctgga aaaaatcact
     1021 tcagtttgct tgctgtttct gagcgaccaa ttaggtaatc aacggaaata tcgtaaaagt
     1081 cagcgatata gattaattca atgatgcttg gaatttcttc tccttcttcg tacttacgat
     1141 atttgaataa aggaatactt aacgcgctag aaacagctac ttgagataaa gatcggccag
     1201 ttcttaagaa attcagacga caacgtaaag tatccagtaa aatagcttct tcgatactca
     1261 tttaatcacc tttcattata gtagaatagt tataatgact atagaaagct acacatgcaa
     1321 tcaatagtac tcaatgtttt ttatttaaac gtatcaaata aagaatgacg atcaataaag
     1381 acaaaaccag tcctgataat tcttctataa aaacactatc gggttcaaag tagttgtaat
     1441 taaaaacttt ccacataaag tagatagccg gaagagtcaa aatagctaaa taaaaccgtt
     1501 ctttgttcca attcataaga taaacaatac ttgcgaccag tgcgaccgca ggcacccaaa
     1561 acaaaactct caccaacgta atcatgtaac ggactcctca acgattcata taataaaaga
     1621 taacatgtta ttgcatacat cacaaatgaa atgctaggaa aataaaagaa gaatagatca
     1681 atgaaaaatg aaaaagcaga acagttttct gctgataagc aggaactgtt ccgctgaatg
     1741 tgtcttatct atcgagaaaa aatcaatgga ttgatatcta agtaattcaa tacatataaa
     1801 aagaggacga tcgcattcac taaaaaggaa agaatgatga tcccatagcg aatggaaaca
     1861 tatttaacaa atacttttgt ttgaatacgg gcatatcttt ttcctttata gctgagcatc
     1921 atgacaagaa gcaaaagggt aatcacacct tgaaaaatca ttccaataaa cagaattcct
     1981 gaggtttgat aatttaattg gagaaaataa gctgctgccg caactaaatc gaataaaatc
     2041 gcaataaatg gcaaaataat cactcctaac attgagaata aata
//
LOCUS       DACGDM010000190         2060 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.198, whole genome shotgun sequence.
ACCESSION   DACGDM010000190 DACGDM010000000
VERSION     DACGDM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.198"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            828..1301
                     /locus_tag="IXR05_002900"
     CDS             828..1301
                     /locus_tag="IXR05_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAQ4261326.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1310..1537
                     /locus_tag="IXR05_002901"
     CDS             1310..1537
                     /locus_tag="IXR05_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261327.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          667 a          331 c          313 g          749 t
ORIGIN      
        1 acgaggtatg tcctatgatg aaaagattgt actattcatt gatcataacg attggctatt
       61 tgattgtatc aaatctagga aatatggtat ttggtatcag taaagaattc agttggacta
      121 ctacattatg ggaatctcta ttctttttca tcttcgtatt tttgttacaa aattatcgaa
      181 aaaaataaac atgtgccatc tatctgttgg cacatgtttt aggatttatg gtacttttta
      241 ttcggcaatc cattttattt ttctacttct tcttaatacc tctaacactt ttgatttata
      301 aactaatcca atgcatctac ttgcgcttat taagctattt cagctagata gtaccacccc
      361 atgcgtcaat gcttgatttt ccttttgtat aacattgtat aagcaataaa ggacaaataa
      421 gtggtgatta caccaaacca ttgaataaga aaaattctga tacgtaaata aacatgaact
      481 tgaaaaaatt aatgaatcgg ttagctacta cgtagttgtc ttttttctca tacagttctg
      541 ttaacttaca cttctcttcg ctagataata aaaaatcctc caactgtatt gtccaatata
      601 atcccaggca tctaaactag cattatagaa gagacacaca tagaatctaa aataactggt
      661 tttaaatgtt tcttacaatc aaaaaaagct gttaaatgca ctccacacct tcatactcta
      721 tcatttttta taaacgatat atttttattg tttttcgata aaaaatagtt gttttacaat
      781 aattattctg ctatatttta gctatcaaag ataaaagagg gataaaaatg aaatttaaaa
      841 cattgctatt aaaatttgtc gttttaggta taagtgccgt atttattttg ttcggcgtac
      901 ttttttatac tcagatcgct acaagcgaaa aaggattcaa ttttgattgg cagaccacat
      961 tatttgtttc tgtcatttac tttgcccttc tcctagggat cgttattgct tatttcttat
     1021 tgaaactatt gaaaaaaatc gaagataacc aagctttttc cactcaaagc ttaaacatac
     1081 taaaaaaaat cgaacgaacc attttgttta ttggtttcgc cttttttggc ttacttccta
     1141 aatttatgaa agtagcggat ttagacgatg ctccaggttt gatgttggta ggaatcgctg
     1201 tcgtattcat tccttttgca gtatacacat taacaagcgt gctggaaaaa ctgcttgaac
     1261 atgcgatttt acttaagaca gatcatgatt tgacagtgtg aggtgcgaca tggcaattat
     1321 cgttaattta gatgtagtat tagctcaaaa aaaaatgagt gtgactgaat tgagtgagaa
     1381 agtgggcatt acgatggcaa acatctctat tctaaaaaat ggaaaagcaa aagccatccg
     1441 tttttccact ctcgaaaaaa tctgccaagt tttggagtgt caaccaggtg atttgttgac
     1501 ctataaaaat gactcgaata ctataccaga agaataaaat aaagtagaac aaacagtaaa
     1561 taaaaaataa tctgaatgat agatgtgtga gacttttaga agttatttac gtctattatt
     1621 cagatttttt atttcgattg aataccgttt tatctataaa taagatatgt actgactcat
     1681 acaaaggggg ccttttcttc tccatgtact atcacttttc ctgatacaac tggtttcctg
     1741 ttacgttgta gttggatctg cttttagtat aatactttat tcattccacc agactgatag
     1801 cagtttgagc agtctaaata atcatgtagt attacaggcc attctgtttc ataccttgaa
     1861 gtgcttaaaa cttcagctaa tggcccattg tgttaactct tactccattc ttttttagta
     1921 agctcccata tatactgtaa agccttctat atattatgtc atgttgcttt ttaacattta
     1981 ctatgtagtt ttgataaaat gatttgaata acagtgatgg acaattcttt tttattttta
     2041 acattatttt gataataatg
//
LOCUS       DACGDM010000191         2058 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.199, whole genome shotgun sequence.
ACCESSION   DACGDM010000191 DACGDM010000000
VERSION     DACGDM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.199"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..337)
                     /locus_tag="IXR05_002902"
     CDS             complement(<1..337)
                     /locus_tag="IXR05_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4261328.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAK"
     gene            complement(404..559)
                     /locus_tag="IXR05_002903"
     CDS             complement(404..559)
                     /locus_tag="IXR05_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010001600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4261329.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
     gene            1176..1397
                     /locus_tag="IXR05_002904"
     CDS             1176..1397
                     /locus_tag="IXR05_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261330.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            1398..1655
                     /locus_tag="IXR05_002905"
     CDS             1398..1655
                     /locus_tag="IXR05_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261331.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1791..>2058)
                     /locus_tag="IXR05_002906"
     CDS             complement(1791..>2058)
                     /locus_tag="IXR05_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4261332.1"
                     /translation="SDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDL
                     IDYAMSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
BASE COUNT          678 a          462 c          314 g          604 t
ORIGIN      
        1 ttttagcata ttgaaatttt tctggattat ccatatgagc aaaatatcgc accatacctt
       61 ttgcattagc acatttttgc gggtttggag accgaagctt ttgagttatc tcacgtattt
      121 gatcatacgt ctttttaccg ctaaacatta tcaaaacatg ccaatgaggc tttttcaatt
      181 caccgtcagg attcacatct ttatcatgaa gtggactctc aacccaagga acatgtaact
      241 catctaaaaa ctccctccaa ttttcaggag ccgattcagg atagactaca aacgtccaat
      301 tccttgtgcg ttcatcttta gtttttctac tcgtcatgct ataattacct taattgaaca
      361 acagtctaac agcaaaagca gtgcgccaac actaatgctt ttgctatttt ttttgctcat
      421 tttcctttcc gttagcatta acccaaattg taataagacc agacttacta agacccattt
      481 gtttcgcaat tttatcaaga ttatctgcca cttccttagt aagcgttaca acgactctct
      541 ttttttcatt actgatcata attcgtatcc tccaacgact ttttcttaaa aaccatagta
      601 acaaaaaagt aactaaggtg caacagttta gatactaatt agcgaataat aggccttaaa
      661 cccttggcat tactgatttt gtcaaaaaaa aacgctgaaa cccttgggag agtaaggcta
      721 aacagctatc gaccaatgac caatgaccaa taaggggggt gtcgtagtcc ccccctcctc
      781 cgcccaattc ataaacacca aaaccaaaaa acaaacctca gggctccgcc ccgaaccccg
      841 acctccttct accgaaatat atgcaggcgc cacgcttact atttcgttca gctatcggct
      901 tttgcaatct aacacgaccg tttcgctacc agtcgcctta caggctccat tctcgcttct
      961 cttacgtgtt ttaacgattg cgccgataac taaacgaaat agacgctaaa tcgcttaaaa
     1021 cgcaaaatag acccttttta gagcattgat tttttctact agtcatttcg ataatataaa
     1081 attgaccaca acacagaaaa cttatattat aagcttatgt cgtaagtccg acgtactcac
     1141 gtaatataga cggacgttaa atggaaggag cataaatgag agtgataaaa tcagaaaaat
     1201 tcactttggc cgaaattatg acgaccagcg aacttgcaca agaacttgat tacaaccaag
     1261 cttacgtttt gcgcttagcg aaagaacatc tgactgaagg aaaagaatat cgctctgccg
     1321 gtagaagaaa ctatcttttc agcccagaag cccttaaaaa actagaaaaa gtcataacca
     1381 ccaaagaagg tgagtaaatg cctaaagaaa caactatcaa cgttgaacaa ctagaaaaat
     1441 tgctagaatc atattccaat gattttatcg aattgaccgg cggaaaagtc gaagaaacca
     1501 ccgacctctt tgacctactt ctcacaaata ttctggaatt aaactctgaa gaacaaaaag
     1561 agcataaggg aaaactgata gcaccttcct acaggaaggt ggctaagtcg gctgtgccaa
     1621 ctggttttct tacaaaacaa ccttatattt tttgatatca caaaaaaatc cattttggac
     1681 ctattttcgg tcataatata gtacctactt ttggtcatag tttcgtccgt agttttggtc
     1741 atagtgacta agactttcac gcacaaaaaa agagctgaaa ttaacagctc ttatccttta
     1801 tttatttttg aatttacact tccaccatga cgattcgatt ttatatattg cccgataata
     1861 taagctgaat tatcacaaag aagcggaaac caatcatcaa atctttctga cattgcatag
     1921 tcaattaaat ctttgatttc agtgatattc ttagaatcaa caaacgacat catctctcta
     1981 atcaactcat atcgttctgc actcgttact gacaaataac tagcaatttc tgcaccacca
     2041 tgagcgataa tatcactt
//
LOCUS       DACGDM010000192         2013 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.200, whole genome shotgun sequence.
ACCESSION   DACGDM010000192 DACGDM010000000
VERSION     DACGDM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.200"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            193..807
                     /locus_tag="IXR05_002907"
     CDS             193..807
                     /locus_tag="IXR05_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261333.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(972..1796)
                     /locus_tag="IXR05_002908"
     CDS             complement(972..1796)
                     /locus_tag="IXR05_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261334.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
BASE COUNT          679 a          336 c          290 g          708 t
ORIGIN      
        1 aatcttaaca gataaatcaa gttatatact agaaaattca taaaatatat ttttaatgtc
       61 ataatcgttt aaattttctt gattgacatt tatttacaaa aaatattgcc atttaaaaag
      121 aaaagtgaca tatggcttcc tcgtgtatga ttagggtgta ttttaaatag ttgcagaaag
      181 taggtaaaag ttttgagagt tgcatacata cgtgtctcat cgatcgatca aaatgaacaa
      241 cgccagattg aagaaatgaa aaaattcggt gcagagagaa ttttcatcga gaaacaatct
      301 ggcgcaacga ttactcatcg acctgttttc caagaagcat tagattacgt ccgagatcaa
      361 gatattttta ttgtggaagc tattgatcga cttggaagaa attatgacga gatcatcgct
      421 tcagtcaatt acttgaagaa gaaaaatgtg aagctgatca ttactagttt accgatcatg
      481 gctgaagcaa ttggcaatcc tctcctggat aaattcatta aggatctgat catccaaatt
      541 ttggccatga tcgctgaaca agaacggact gaatcgaaac gtcgccaggc acaaggaatt
      601 aagatcgcaa aagcaaacgg cgtctacaaa gggcggccca aattatacag tgcagacgca
      661 aaagatcccc aacgtcgcct tgtttacaaa agcatcgttg aagatcttaa aaatggtgtt
      721 gcgattgcta agattgctaa agactacaat gttacgagac aaaccgtgta tagaataaaa
      781 aaagacagca tggtcaatga caaatagttg atcatgctgc ttttattatc ttctcatctt
      841 taatttccta catataatta ctatctataa aattaagtct tactcagaac agataaagca
      901 taaaattcca acaaaccatt ttttacttaa ctaaataaag agtctgttaa tataatcttc
      961 acttatttac gttaatcccc tactgtattt gttggttcct tatctatatt ttctacaaaa
     1021 tccttattat cttgtgattt agcttcgtat aattctttgt atgtcgacac attggttata
     1081 ctaattccta tagctagttc ttgagactct acttttctct ctagctcctt tgacaaagtg
     1141 atttgagatt tatttggttc cgttggagtc aattctatag attcttcata aaaatctcta
     1201 tacataaagc tatcattaat tttataaaaa aaattaaatg tttttagcac tgccatataa
     1261 cattcaaaac attcttctat agttggttta cttccttgag gagaatgaac caatttatta
     1321 cgtttttcta tgaaattttt aatttccttt cttatttctt tcggaaactc aatattaaag
     1381 taccctttaa acatgctccc taataatttg tctacagggg gagattgtaa attctcaaat
     1441 attagagtta aatcaggttt ctcttgttga taaaattcct ttacccctat ttcacaggct
     1501 gtaattatcg aaataaacct atctctagta tttgatatat ttttacttct tttaaggagt
     1561 ataagagaaa aggggatact ttcgtgtcca tgcatgtaat taactaattg ttgagcttca
     1621 gaagttatat ctctaattat atagttaacg gaattaggaa gtgtctttaa ctctaatgaa
     1681 atttctatcc aattactatc ttctaatctg tatatgctcg aagtataatt tgattcgtca
     1741 gcaagcatcg ctacatccca aacactgatc ataaaatctt ttaaacgttc aatcatttca
     1801 gcaatattgc taaaatcagc taatttttct ttagaataaa aaaaacattt atatcagaat
     1861 caataaattc tatttttttt attactatat cgtcatcatt atcttgacca tttatgttta
     1921 ttgttccctg agtggggagt acttctttca aattcaagtt aaatttatat tccattactt
     1981 ctcctccaat atataaaaat tacttaactg tat
//
LOCUS       DACGDM010000193         2002 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.201, whole genome shotgun sequence.
ACCESSION   DACGDM010000193 DACGDM010000000
VERSION     DACGDM010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.201"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..378
                     /locus_tag="IXR05_002909"
     CDS             <1..378
                     /locus_tag="IXR05_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAQ4261335.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="IXR05_002910"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="IXR05_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAQ4261336.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2002
                     /locus_tag="IXR05_002911"
     CDS             1859..>2002
                     /locus_tag="IXR05_002911"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4261337.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          554 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tt
//
LOCUS       DACGDM010000194         1942 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.202, whole genome shotgun sequence.
ACCESSION   DACGDM010000194 DACGDM010000000
VERSION     DACGDM010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.202"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(670..960)
                     /locus_tag="IXR05_002912"
     CDS             complement(670..960)
                     /locus_tag="IXR05_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261338.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1168..1860)
                     /locus_tag="IXR05_002913"
     CDS             complement(1168..1860)
                     /locus_tag="IXR05_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4261339.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQALTDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          533 a          370 c          298 g          741 t
ORIGIN      
        1 ttaagcatta cttaaagata acttaaaagt tatcttttaa atacttaatt gttaaatacc
       61 ttatttgatg caaaagaaat ctacgatagt caacaaaaaa attttcatta tatccagaaa
      121 aatttttctt agttaaggac ctatggattg cagtaatgca gaattcgtcg aataaactgc
      181 caaagacata caatcatatt gcttttaaaa ttgacgaaca agatatagat tcgtttgtct
      241 caaaaatcca aatgttaggt ttaactgtcg aaccaggacg ttctcgtgtg aaaggcgagg
      301 cttcttcaat ttacttttac gactatgata atcacctctt cgagttacat accggtactc
      361 tccaggaacg tttaaaatcc tacaattcca ctacctgaga ctagtaatga ctagtctctt
      421 tttatggcct ctgatccccc cattgagcga atactaatag ggcttcgaat tgatctgttc
      481 aatctttaag caatatccct caaatgagtt tggaaagttt agtgattcat cacaaatact
      541 taaatacatg tagttatata tagattgagg ttcttgtgag cgtatgctcg tgtgggttca
      601 aatcccatcg tctgcatcca tctttccaaa acaagcggct aggacatttt tgtctcagcc
      661 gcttgttttc tagtttattc tttcatcttg tcggaccttt tttcttgggt atagactttt
      721 ctcatattct accacaattt tgggtttccc taacacatga taggatctca caacaaattg
      781 ctttctatta ttataataac ctgtaacgac taacttcatc ccttcgtcta cttcagctag
      841 gaagttcaaa ctatgggaag caatcaaaca attgacccca tttaaactga aacggatcaa
      901 cggtctggca ctaacttgca aagtacggat cttatctact gttccatatt ttttctccat
      961 aaccttcacc tcaataccat tatacgaaca tacattccct ttgtaaagaa gaaactctgt
     1021 tttatctttt tgactttttg tctattacct ttcttaaaat catattggca cttcctgcga
     1081 agatgaagga catgtactaa aaaaaagagg cagcagtata gattactgtt gcttctttac
     1141 taatttaggt ttacttgtta agaaagatta tttacgcaaa tgttcttcaa caatttgctg
     1201 agatttatca gctgtatctt ccacttcatc ttttgctttt tctaactttt gaatatattg
     1261 tttcaagctt gagttttcag cagttgcttc gtctaatttc ttttgtgtat ctgttaactg
     1321 agtttctaca tttgtttttt cttgtgtcag tgttgcgatt tgttgattca aaccatttac
     1381 agtattttgt aattctgaaa gttttgcttg tgcttcttgt agtcttgctg tccaatctgc
     1441 attcagatga ttgatttcat catttttttg gttgatctca tctagtttga cattgatttc
     1501 attttgtttg ctttgtagtt gtgcatcctt gctgactaat tgactttcta agttttgttt
     1561 ttctgctgcc gattgatttt tttggttttc taattcattt acttttgttt ggtattcttg
     1621 gacatctgcc tttgaatctt gcaatgtctg ttctttttgt gctagtcgag cggtaagatc
     1681 tgtaagcgct tgctctttat ctgtcaatgt atgatcaagc tgtgtcagat tctcattgat
     1741 tgtatcaata tctgtctctc caccccacaa aataatttca tttgcgtacc gcgtgcctgt
     1801 gtagccaatt agacatagaa atgcaacgac aatcccacca gtaataaatt tctttttcat
     1861 ttgcatagct ccttaatcca atacttttac atgctaaaag taagtgatct caaacacaat
     1921 gtcaagcgtt tttaaattac at
//
LOCUS       DACGDM010000195         1926 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.203, whole genome shotgun sequence.
ACCESSION   DACGDM010000195 DACGDM010000000
VERSION     DACGDM010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.203"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            74..1540
                     /locus_tag="IXR05_002914"
     CDS             74..1540
                     /locus_tag="IXR05_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4261340.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKKITEPETVVQP"
BASE COUNT          591 a          329 c          396 g          610 t
ORIGIN      
        1 gtcttgtaag tttgttaaaa attgaatatg attacatctg gataacaaat ttttatcata
       61 aaggagagaa cgaatgaaca acaaacaatt acgctggttt actgttgcgt taattgcatt
      121 taacatggtt tggggcatgg ggaatgtagt taataactat gctcagcaag gagtatcagt
      181 tgtcacctct tggctattga ttttggccat ttattttatt ccatacgcat tgatcgttgg
      241 acaattagga tcagccttca aggatagtaa aggaggcgtc agttcatggg tcgaaaatac
      301 gacatctaat aaacgactgg catactatgc cgcttggact tactgggtcg tccatattcc
      361 ttatttggca caaaagcctc aagcaattct gattgctggt ggttgggcag tccaaggaaa
      421 tggaaatatc gtaaatacga tgtcagtaca aatggtagca gttatttcac ttattatatt
      481 tcttgccttt ttatatttat caacaaaagg actttctact ttgaaagtga ttggcggact
      541 ggccggaaca gcgatgttcg tcatgtcgat cttatttatt cttttagctg taacggcacc
      601 gttcatcaat ccaacgatgg aatttgccac accacatatg aatcaagtga aaacatatat
      661 tccaacattt gatttcagtt atttcacaac cgtttcgatg ctagtatttg cagttggagg
      721 ggcggaaaaa atatcccctt atgtcaactc tacaagaaat cctgcaaagg aatttcctaa
      781 agggatgatc ttcttagcag caatggtagg gatttgtgct gtattaggct cagtcgcaat
      841 gggtatgctg tttgctagtg ataatattcc taaagacttg atggcaaatg gggcatacag
      901 tgcttttcaa attttaggta attactatgg tatcggtaac tcattgatga tcatttacgc
      961 attgacaaac atgattggac aaatctccgc attagccttt tcaattgatg caccactaaa
     1021 aatcttgtta gcagatgcgg atccagaatt tgtaccaaac tggctacgta aacgtaatcg
     1081 taaaggtaca ttggtgaatg gttatcttct gacaggtata ctagtaggaa tcattatttt
     1141 gttgccgatt tttggtatca aagatatgaa tgaattagta aaatggttga cgaacttgaa
     1201 ctcagttgtc atgccaatgc gttacctatg ggtgttcttg gcatatatga tgttgaataa
     1261 agcttataag aaattcaatt ctgaatataa atttgttaaa aatccaaaaa tcggttttat
     1321 ctttggtgct tggtgctttg ccttcactgc gtttgcatgt atcctaggaa tggtgccaaa
     1381 agtagattat actgctgatc ctaaagcatg gtggttccaa ttatttacga atatcatcac
     1441 accaatcgtc ttgatcttat taggtatgat cttgccagca attgctcgtc gagacaaaaa
     1501 caaaaaaatc actgaaccag aaacagtggt tcagccttaa aatagaaata cttgttacaa
     1561 gaggttgtga cagaagtggt cagcttcaag aaataagaag gaatttacga aaattgcttc
     1621 tcaaattttt gtgaagtttc ggcttgtttt tcgaagaagc tacttctgga acaccgtgaa
     1681 tcagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagc
     1741 ccctcatatt tttcgtttgg ctgggcttat taccgcagat gcaagctttg gaacaccgtt
     1801 taaggaagag gttgtaaaat cagcgatttg acctgagtat tagagaaaca aacggaaaaa
     1861 tagctcctca tattttgccg ctttttgagc taatgctgaa ggtcagctga ttgaacacca
     1921 tttatt
//
LOCUS       DACGDM010000196         1920 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.204, whole genome shotgun sequence.
ACCESSION   DACGDM010000196 DACGDM010000000
VERSION     DACGDM010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1920
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.204"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..153
                     /locus_tag="IXR05_002915"
     CDS             <1..153
                     /locus_tag="IXR05_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4261341.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFSFSVSTEIKV
                     LMGITA"
     gene            159..575
                     /locus_tag="IXR05_002916"
     CDS             159..575
                     /locus_tag="IXR05_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261342.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            681..944
                     /locus_tag="IXR05_002917"
     CDS             681..944
                     /locus_tag="IXR05_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4261343.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            944..1216
                     /locus_tag="IXR05_002918"
     CDS             944..1216
                     /locus_tag="IXR05_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4261344.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1293..1622
                     /locus_tag="IXR05_002919"
     CDS             1293..1622
                     /locus_tag="IXR05_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4261345.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1612..1898
                     /locus_tag="IXR05_002920"
                     /pseudo
     CDS             1612..1898
                     /locus_tag="IXR05_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT          730 a          235 c          382 g          573 t
ORIGIN      
        1 aataaatttt atcaaagtct ccgtacagcc tcttccacga ttaagggcat ggagaccatt
       61 cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct tcagcttttc ggtgtctact
      121 gaaatcaagg tattaatggg aataacagcc taagatattt ggagttcaga gagggcgcgt
      181 ttgattttca aacttcgcaa cagaaccgaa aatttatacc ggaagatttt caaaacttac
      241 agttagaaaa catgcgttta gaagatttat ttagattagc agatgatgat aagtatagat
      301 ttgaagtttt gaaaattaaa aagaatgaac tattgaataa gttatatcct gagaatgcga
      361 taaaagcaca ttttggtgat gctaatcata tgtatagttg gttcattcct aaaagattta
      421 gagggaaaat caatgctgga gatcaagtga aagtactcaa tcgaaatagt acagatgtcg
      481 taatgataac agatatctac gtagaagatg aagttataat caaatatatg aagcctgtga
      541 taaaacttgt taataaaaat aaaggaaacg gataacactt tacaatgctg ttttggtact
      601 ccaatttaaa caaaacaatc gaatttacgt acttaattaa gtacgttaga atggagatat
      661 aaattagagg gggagtagat atggcaaaaa cagtcttaaa tcctagctca gcacggaaaa
      721 atttttataa gttgttgaaa gatgtaaatg agaatcatac ggaaattgaa atcattagtg
      781 agcgcagtga aaataatgcg gtgcttattg gtttggatga ttggaaagca atcaaagaaa
      841 cgctattact tgagcaaata ggcactttgg gtgttgttcg taagcgagaa aaagatgata
      901 gtggatttac taatgttgat gaaattgatt gggataactt ataatgaata actattctgt
      961 gatgattaaa aactcggcta aagctgattt aaagaaaatc aaacagtcta atttgaaacc
     1021 tcaatttgag aaggttattc agactttaaa ggaagatccc tatctcccta cccaatcatt
     1081 tgagaagtta aaacctacac atgaaggtag gtattctaga agattgaata gacaacaccg
     1141 ggttgtttat aaggtagatg aagatgaaca cgtggttgaa atttattcag caaggacgca
     1201 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
     1261 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
     1321 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
     1381 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
     1441 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
     1501 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
     1561 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
     1621 gaaatcgttc cttcaaaaca tgtcattaag tatttaaaaa gctaaaagag aagccattga
     1681 aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat aagggtgaac
     1741 aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg ggcacaacat
     1801 atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta tgtggaacgc
     1861 atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc gttcttaaga
//
LOCUS       DACGDM010000197         1849 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.205, whole genome shotgun sequence.
ACCESSION   DACGDM010000197 DACGDM010000000
VERSION     DACGDM010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.205"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            198..395
                     /locus_tag="IXR05_002921"
     CDS             198..395
                     /locus_tag="IXR05_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261346.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            501..983
                     /locus_tag="IXR05_002922"
     CDS             501..983
                     /locus_tag="IXR05_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261347.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1041..1637)
                     /locus_tag="IXR05_002923"
     CDS             complement(1041..1637)
                     /locus_tag="IXR05_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4261348.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT          576 a          276 c          368 g          629 t
ORIGIN      
        1 ttttaaggaa tatgttttaa ttttttgaaa aaaattcttc taaatacaac agctgtttta
       61 attgtgaaaa cgaaaacagt acgctataat gcctgtaagg ttgattttta actgtaaata
      121 aaaatcaatg agttaaatct ccaaagaaat agcagtggta atgtggagaa aagttccagc
      181 agtttaggag gattttgatg acggaagaaa tgattaattt aggagaacaa tatgcatgca
      241 aaccaattgg ttttacaaaa acggtcattg gtgaagttgt atcaaaaatg acaaactgcg
      301 ccgtggtcaa agttgcccaa tgtgctgcag aggaccaaga attattagat gaaaaagcaa
      361 gcatggttgt tgcaaaatat gatacatttg aataaagaaa acaattggac gtgcggcgtg
      421 ctgcaagtcc aatttctttg agaaggtaaa tcagtattct tttcctattt tctggagaag
      481 aaaaagcgag gcgagttgtc atggtaacat tctttacggt tctattgttt ttattcgttg
      541 ttgtgatgtt tttatttctt tggctggttc gaaaagaaat tatttatcgg actgtgcgaa
      601 atcgatgggt ctacttggtg atacccttct tagtgtcact agtcatttgg tatacactca
      661 tcagtcatcc tacagcagat gaattggcaa aagggatctt gtcagcaatg atttttatta
      721 gttttttgtt ggacagtaga ggaatcacag aagaaggact tgttttgaat agctttgaca
      781 aaaaaggtgt tcctttttct gagatcaata aaattgtatt atatcagcca aaaggttcta
      841 aaatcgtaaa aatgaatttt ttccgaaacg gatggcgagg accgatgctg aaattttctg
      901 catcattaga agaattagtt ccatttttgt cccaacgctt aaacgatgag gcagagattg
      961 atattatgat tgatccagaa taaaaacaga ggttgcgaca agatgtttgt cacaacctct
     1021 gttttttatt tcaaataaaa ttatccaaat acgcggaagc gatcggcatc gttcatgtat
     1081 tctttttccc cagccggtgt ttctggtgaa ccgaatacta attgcgaacg tagtttccag
     1141 tttgaaggga tattccattc ttttgcaact gcttcgtcaa taactgggtt gtaatgttgc
     1201 aagtttgcgc ccaatccttt atcaactaat gctacccaag tattagctgt tgcgattccg
     1261 tttgattgtt ctgaccaatc tgggaagttg tctgcatata attcaaattg ttcttgtaga
     1321 ccttttacca cgtcagtatc tttgaagaat aatactgtac cataaccatt tttgaaacca
     1381 gctaatttgt tttgtgtatt tgggaaagct tctgctggag tcaatgggcg aagtgcttct
     1441 tcagtgattt cccaaagttt ttcatgtgca tctccgaaaa ggataactgc gcgtgttgat
     1501 tgagcattga aagcagttgg gctttcttta attgcttctt tgatcaaagt tgttaattct
     1561 tcattagaaa gtgaaacatt acgtcctaga tgatagattg aacggcggtt tttcaaagtg
     1621 tcagtaaaag ttgtcataat aaaatttctc ctttgatttg cgttttgcat ttttttaatt
     1681 gattacgaaa tgaagtatag caccttacaa aaagtaagta aacagatatg ctcacaaaaa
     1741 ataagcgaag ttcaaaaaac aattttaata agaaaaatcg ttatgtaagg attttcttag
     1801 ttatcgcttt cattgttgtg ttttaggaat ttttgcttat ttgaaaaaa
//
LOCUS       DACGDM010000198         1798 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.206, whole genome shotgun sequence.
ACCESSION   DACGDM010000198 DACGDM010000000
VERSION     DACGDM010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.206"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(146..1315)
                     /locus_tag="IXR05_002924"
     CDS             complement(146..1315)
                     /locus_tag="IXR05_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HAQ4261349.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            complement(1386..1787)
                     /locus_tag="IXR05_002925"
     CDS             complement(1386..1787)
                     /locus_tag="IXR05_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HAQ4261350.1"
                     /translation="MFAPNETHNLSDEFFKMFLKRYIDSNDDTKAAINYFDALLNSYE
                     DLIVYRENKNIDILLVSEKNKIVVCIENKILSSESGGQLNKYQIYIERNYSNYKKIFV
                     FLTPDGNEPTNPSWGIITYKNIVEESVKYFV"
BASE COUNT          587 a          298 c          252 g          661 t
ORIGIN      
        1 aaattagcat atgaataacc gtgctaccaa gcttttcatt aataaaatat ttttattaat
       61 attttataac tttacgcaag atcataattt tgtcgggagc gtcaataatt ttgtgtaaat
      121 ggaaaagccc attctgttga tcaagttaaa acattgattc taatgtatca tgtatttctt
      181 taaaaccttt atgaactcgg catagaaact tttgattata gttgttgaat tgagatacta
      241 gaaatctctc cagagattct tcattaggaa attgctcttt tcttttggta tatttcttta
      301 attgtttgtt aaaaccttca atcaaattag ttgaataaat agttcttctg attgacggag
      361 ggaaattata aaaggttaat atagcaggat tcatgagcaa tttaaccact cgtggatact
      421 gctttttcca tttatctatc ataaacctta tttgattatt tgcttcttct tttgaacttg
      481 cttggtaaac taatttgaaa tcgctacaga tttcttgtcg atcactaaca cgaaccttat
      541 gagcgatatt tctagatata tggacacaac attgttgaaa ttgagcattt ggataaacac
      601 tatgaatact atcgtcaata ccacttaaac catctgttac gactaacaaa acctcttcta
      661 aaccacggtc ttttagatct tgaagaatct ctttccaaac ataagcagat tcagttggag
      721 ctatagtaaa tcctagaacc tctttagttc catccaacct gataccaatt actatataga
      781 cagcttcttt tgatacggtt tgtcttttta agggaatatg agtagcatcc ataaaaatga
      841 ctgagtattt agcttctaaa gttctttctt taaatgccga aacatcttca gacacaattt
      901 tactcatatt tgaaatagtt tgtggtttgt aataatgacc atacattttt tcgattagat
      961 cagagatttc ggacatagta attccttttt gaactagctg aataatagtg gtttctaaag
     1021 agtcattggt tcttttataa gcaggtaaag tttgttgaga aaagtctcca ttcctatctc
     1081 taggtattac taaattcaat tcaccgtact ctgttttaaa agagcgcgaa taattcccat
     1141 tacgggaatt acctgaatta aatccagctc tatcatactt ttcatagtca agaaataccg
     1201 ttaattcagc ttgtaataaa gcgttaatag ccaattctag gtgacgacga aacaaatcat
     1261 ccaaatcacc tttattgatt agtatttcca taatttctgt agtaaaatcg ttcatatgga
     1321 agtcctcttt tctgtgaatg tgttgtggta actctattct acagaaggga cttccttttt
     1381 tctatttaca caaaatattt tacactctct tcaacgatat tcttgtaagt aattatgccc
     1441 caactaggat ttgtgggttc atttccatct ggagttaaaa aaacaaaaat ttttttatag
     1501 ttagaataat tgcgttctat atatatttgg tatttattaa gttgccctcc agactccgaa
     1561 gacagaattt tattttcgat gcacaccact attttatttt tttccgatac caataaaata
     1621 tcaatattct tattttctct gtaaacaatt aaatcttcat agctattaag taaagcatca
     1681 aaataattga tagcagcttt ggtatcatca ttagaatcta tatacctttt caaaaacatt
     1741 ttaaaaaact catcagataa attgtgggtt tcatttggag caaacaaaaa agctaaaa
//
LOCUS       DACGDM010000199         1642 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.207, whole genome shotgun sequence.
ACCESSION   DACGDM010000199 DACGDM010000000
VERSION     DACGDM010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.207"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..>1642)
                     /locus_tag="IXR05_002926"
     rRNA            complement(<1..>1642)
                     /locus_tag="IXR05_002926"
                     /product="23S ribosomal RNA"
BASE COUNT          348 a          507 c          350 g          437 t
ORIGIN      
        1 taagtcctcg atcgattagt atcagtccgc tccatacatc actgtacttc cactcctgac
       61 ctatctacct gatcatctct cagggatctt actttcttaa agaaatggga aatctcatct
      121 tgaggtgggc ttcacactta gatgctttca gcgtttatcc cttccctaca tagctaccca
      181 gcaatgccct tggcagaaca actggtacac cagcggtaag tccatcccgg tcctctcgta
      241 ctaaggacag ctcctctcaa atttccaacg cccgcgacgg atagggaccg aactgtctca
      301 cgacgttctg aacccagctc gcgtgccgct ttaatgggcg aacagcccaa cccttgggac
      361 cgactacagc cccaggatgc gacgagccga catcgaggtg ccaaacctcc ccgtcgatgt
      421 ggactcttgg gggagataag cctgttatcc ccagggtagc ttttatccgt tgagcgatgg
      481 cccttccatg cggaaccacc ggatcactaa gcccgacttt cgtccctgct cgacttgttg
      541 gtctcgcagt caagctccct tctgccttta cactcttcga atgatttcca accattctga
      601 gggaaccttt gggcgcctcc gttacctttt aggaggcgac cgccccagtc aaactgccca
      661 tctgacactg tctcccacca cgattagtgg tgcgggttag agtggccata acgcaggggt
      721 agtatcccac cagcgcctcc atcgaaacta gcgttccgat ttctacggct cctacctatc
      781 ctgtacatgc ggtacagaca ctcaatatca aactacagta aagctccatg gggtctttcc
      841 gtcctgtcgc gggtaacctg catcttcaca ggtactaaaa tttcaccgag tctctcgttg
      901 agacagtgcc caaatcgtta cgcctttcgt gcgggtcgga acttacccga caaggaattt
      961 cgctacctta ggaccgttat agttacggcc gccgtttact ggggcttcaa ttcgtacctt
     1021 cgcttgcgct aagcactcct cttaaccttc cagcaccggg caggcgtcag cccctatact
     1081 tcatcttacg attttgcaga gacctgtgtt tttgataaac agtcgcttgg gcctattcac
     1141 tgcggctgat cgtatgatca gcaccccttc tcccgaagtt acggggtcat tttgccgagt
     1201 tccttaacga gagttctctc gctcacctta ggattctctc ctcgactacc tgtgtcggtt
     1261 tgcggtacgg gccgctgttt tctcactaga agcttttctc ggcagtgtga catcaggaac
     1321 ttcggtacta ttatttccct ccccatcaca gcttgtcctt aagaaaagaa gcatttgact
     1381 cctcttcaga cttactgctt ggacagacat ttccgatcgt ctgcattcct tagcctcctg
     1441 cgtccctcca ttgctcaaac aaaaacaacg ggtacaggaa tatcaacctg ttatccatcg
     1501 cctacgcctg tcggcctcgg cttaggtccc gactaaccct gggcggacga gccttcccca
     1561 ggaaacctta gtcattcggt ggacaggatt ctcacctgtc tttcgctact cataccggca
     1621 ttctcacttc taagcgctcc ag
//
LOCUS       DACGDM010000200         1625 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.208, whole genome shotgun sequence.
ACCESSION   DACGDM010000200 DACGDM010000000
VERSION     DACGDM010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.208"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..1022
                     /locus_tag="IXR05_002927"
     CDS             <1..1022
                     /locus_tag="IXR05_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAQ4261351.1"
                     /translation="KKLQMGEIVRGPSQISIDVTYKCNFRCKHCYNASGGDNCFMDNE
                     LTDDELLELTKDICNLKPYNICFCGGETLLRKKIVLSCATLLKEAGIPNIAIVTNGSL
                     VTQDVAKELFKAGINRFQVSLDGKNASSHEALRLYPNSFEKAINAIKLFRELSEEVDV
                     AFCPTSFNYNQLREVYQLVNTLKVKSLRIQPFMLSGRGMQNREIVPTVSQYRKLVSDI
                     NYIKRNEDYTKIDWGDPIDHIIRHRTLLKDFSNFVSIRSDGGLMASPYLPIQVGNIKC
                     HSLSKYWRAGLYKVFSLDLVQDIATQVSSIQDMSKELKKGHIKWLNEDIEIDILDEYK
                     HDILI"
     gene            1078..1296
                     /locus_tag="IXR05_002928"
     CDS             1078..1296
                     /locus_tag="IXR05_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261352.1"
                     /translation="MISEPQMNNMYESPTIMGAGEAAPRACSAIMVCVLLASAGVGIQ
                     AGAVYTYAVVATVAVAAAAVWKTVGLVG"
     gene            1367..>1625
                     /locus_tag="IXR05_002929"
     CDS             1367..>1625
                     /locus_tag="IXR05_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261353.1"
                     /translation="MKYNNLKPKLLNENIEYIREENYGYLTIVPKNGTELKDNVFNPT
                     VRYILANCTGKNSVKKIANGLKKKFPSLEYEKFYQDVVGTIK"
BASE COUNT          609 a          191 c          310 g          515 t
ORIGIN      
        1 gcaaaaaact tcagatgggt gaaattgtta gaggtcctag tcaaatatct attgatgtta
       61 catataaatg taattttaga tgtaaacatt gttacaatgc gagtggtgga gacaattgtt
      121 ttatggataa tgagttgact gatgatgaac tgttagaact tacaaaagat atatgtaatt
      181 taaagccata taatatttgt ttctgtggag gagaaacttt actgagaaaa aaaatagttt
      241 tatcttgtgc cactttatta aaagaggcag gtattcctaa tattgctatt gttactaatg
      301 gatcattagt aactcaggat gttgcaaaag aattattcaa agcaggtatt aatcgatttc
      361 aagtaagttt agatggaaaa aatgctagta gccatgaagc acttagatta tatccaaaca
      421 gttttgaaaa ggcaattaat gctatcaaat tatttagaga attgtccgaa gaagtggatg
      481 ttgctttttg tcctactagt tttaattaca atcaattacg agaagtatat caactagtaa
      541 atactcttaa agtgaagtct ttaagaattc aaccatttat gcttagtggt aggggaatgc
      601 aaaataggga aatagtgcca actgtttctc aatatagaaa actagtttct gatattaact
      661 atattaaaag aaatgaagat tataccaaga tagattgggg agatccaatt gatcatatca
      721 tccgacacag aactttattg aaagattttt cgaattttgt ttctattagg tcagacggag
      781 gattaatggc atcaccttac ttgccaattc aagttggaaa tattaaatgt cacagtcttt
      841 ctaaatattg gcgagcagga ctttataaag ttttttcttt agatttagtt caagatatag
      901 ctactcaagt ttcttcaata caagatatga gtaaagaatt aaaaaaagga catattaaat
      961 ggcttaatga agatatagaa attgatattc tcgatgaata caaacatgat attttaattt
     1021 aggtttatca ttggaaagtt tagataaaca aagtactttt agaaaggagg gaaaaaaatg
     1081 atttctgaac ctcaaatgaa taatatgtat gaaagcccaa ctataatggg agctggtgaa
     1141 gctgcgccaa gagcttgttc agcaattatg gtgtgtgtgt tattagcatc tgcaggagta
     1201 ggtatccaag caggagcggt gtatacttat gctgtagttg ctacagtagc tgtagctgca
     1261 gccgcagttt ggaaaacagt aggattagtt ggttaggaat taataggaga ctaactgtct
     1321 cctattgatt ccaatgatta agctaaggag gaattttaag aaaataatga aatacaataa
     1381 tttaaaaccg aaattactta atgagaacat agaatatata agagaagaaa attatggata
     1441 tttaaccata gttcccaaaa atggaactga attgaaagat aacgttttca atccaacagt
     1501 aagatatata ttggctaact gtactggaaa aaacagtgta aaaaaaatag cgaatggttt
     1561 aaaaaagaag tttcctagtt tagaatatga aaaattctat caagatgttg taggaactat
     1621 taaat
//
LOCUS       DACGDM010000201         1605 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.209, whole genome shotgun sequence.
ACCESSION   DACGDM010000201 DACGDM010000000
VERSION     DACGDM010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.209"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(42..419)
                     /locus_tag="IXR05_002930"
     CDS             complement(42..419)
                     /locus_tag="IXR05_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261354.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(719..1600)
                     /gene="galU"
                     /locus_tag="IXR05_002931"
     CDS             complement(719..1600)
                     /gene="galU"
                     /locus_tag="IXR05_002931"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4261355.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          439 a          360 c          241 g          565 t
ORIGIN      
        1 tatccattat tttatctttt tttgcgtata cctactaaat attaccgtct tcttctcgtt
       61 cttctacttt gttcgagaga atctgtacta gaaaaagtag ttgtatgtct accttttctg
      121 cctatccgag actttctttt catatatggg atataaatga ttagatacag tacagcaaaa
      181 aataaagcaa atacgcaagc ttcccaacta cctaacgcca attcaaccat caaggtagca
      241 accccaacgg atgctgcata ccagataaaa atcagaaacg tttctttttt tctgaccatg
      301 cgaaacatga taaatagact aataagcaat agtggcaaca caaatatcca attgcttcct
      361 tccatcagcc acttgagtat atcaagcagc gactgtgcaa cagcgactaa ttttcccata
      421 gtgaacacac accttttttt ataattaaaa aattcgcctt tttattctac tatgaatctt
      481 ctggcttggc tttcatttct cttatgtaat cattttcttt tatacaactt aaaaaaaaat
      541 taaaccatta gcataatatt ttctgaatct attcacgaaa gtctttttct atctttcgtt
      601 ttccacgact caactgatct agagtcaaaa aactaaaacg acagttgcgc aaatgacgca
      661 caagctgccg ctttaataac aaatagcctt tcattctcag caggccactt atttccagtt
      721 aactttctgt tcttagcttt ttactcaact ggataatata tgcacttaat gaagtcccaa
      781 tttccgaatg ttgaagtcca tattcaatat ttgtcttcat atatcctaac ttatcgccta
      841 cgtcgtatct ttttccttta aactctctcg catagaccgc ctctgtctgg ttaagagtct
      901 gaagtgcatc cgttagctgt atctcgtttc ctgctcctgg ttcttgagtt tctaatatct
      961 caaatatttt aggagtcagt agataacgtc cgataatggc taaattactt ggtgcttttc
     1021 ccatttcagg tttttctaca aaccctttta ctctgcaacg acccttttcg ctatctgttt
     1081 taggatcaat aattccgtat ttagatgttt cattttctgg tacacgcatg acggcaacag
     1141 cggaagcttg tgtttcttca taatccatca tcaattgttg agtcaatggg atatcatctt
     1201 tcatcaaatc atcccccagc atgacgacaa acggttcatt tcctataaat gcttttgctt
     1261 gaagcacggc atcccccagt cctcttggat gagattgacg gatgaagtga agattgactt
     1321 gagtcgtttc ttcaactaaa gcgagtaatt ctgttttttc cttttcccgc aaattgtttt
     1381 ccaattcgat atttgcatca aagtgatctt caatgggtct tttttctttt cccgttacga
     1441 tcaagatgtc ttcgattccc gaatccaatg cttcttccac aataaactgg atcgttggtt
     1501 tatccacgat tggaagcatt tcttttgcca tggcttttgt tgccggcaaa aaacgtgttc
     1561 ctagcccagc ggcaggaatg actgcttttt tgaccttcac ttgct
//
LOCUS       DACGDM010000202         1602 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.210, whole genome shotgun sequence.
ACCESSION   DACGDM010000202 DACGDM010000000
VERSION     DACGDM010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.210"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            92..1558
                     /locus_tag="IXR05_002932"
     CDS             92..1558
                     /locus_tag="IXR05_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAQ4261356.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          446 a          292 c          333 g          531 t
ORIGIN      
        1 agtttatatt tcttaaataa gttttttagt taaatttttc ggtaaagatg tataatattt
       61 tctgaaaatt taaagaattg gggtatagat tatggaaaaa cagcaagaca agggcttctt
      121 cgggcagccg aagggattgt caactttgtt cttcactgag atgtgggaac gatttagtta
      181 ttacggtatg cgtgcattac ttatctatta tatgtacgat acagttgcca acgggggact
      241 tggattacca cgagcaacag cattagctat catgtcgatc tacggatctt tgatctacat
      301 gtctagtatc gtcggcggat gggtatctga ccgagtgtta ggagcaaaac gcactgtatt
      361 cttcggtgga gttttcatta tgcttggcca catcgtcttg gctttaccat ttggtgtaag
      421 tacattgttt gtttcgatgg cattgattat tatcggaacc gcctttttga aaccaaatgt
      481 ttctggcatg gtcggacatc tttattcaaa gactgacttg cgaagagatg caggattttc
      541 gattttttac atgggtgtca acttaggggc attattagca ccactaatcg ttggtacaat
      601 cggtcaagaa tataactatc atttagggtt ctctttagct gctattggga tgttctttgg
      661 attattacaa tacatcatcc aaggacgcaa gacattagac ggagtgggta caacaccgcc
      721 gaatcctttg acaactgaag aacgtaaagg attcatccgt aacttgatca tcgcacttgt
      781 tgttatcgct gcagtattcg gcggggcaca actaactggt catctgacaa ttgacttttt
      841 tgtcaataca atcagtgtat tggggattat cttaccgttg tattacttta tcaaaatgct
      901 gacttcaaaa gatgtaactg ctgaagaaaa accaagagta tgggcttata tcccattatt
      961 ccttgcagca atcattttct ggtcattaca agaacaaggt tcatctatct tagctttatt
     1021 tgctagtgaa cgtacacaat ctacgctatt tggtgtaacg atccaagcaa gctggtatca
     1081 atcattgaat ccaattttca tctttattct gacaccagta ttcgtaacga tgtggacgaa
     1141 acttggtgaa cgtcaaccat ctacagtagt gaaattctct cttggacttt tatttgcagg
     1201 attatcgtac ttgctattga tgttgccggg tatgctttat ggtacaagtg gaaaagtaag
     1261 tccattgtgg ttgttgggaa gtttcttcat cgtggttatt gctgaattgt gtctttcacc
     1321 agttggtttg tctgtgacaa caaaattagc accacgagca tttgaatcac aaacaatcgc
     1381 tatttggttc ttagctgatg cttcttcaca agcaatcaat gcacaaattg cacgcttcta
     1441 cacaccggga acagaatctg cttacttcgg tattatcggt gcagtagcaa tcgtcggtgg
     1501 tatcttgcta tttactgtga aagaaccaat caaaaaacta atgggctcta ttcattaatc
     1561 aatgaacata aaaacaggaa ttgcttattt gcagcagttc ct
//
LOCUS       DACGDM010000203         1578 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.211, whole genome shotgun sequence.
ACCESSION   DACGDM010000203 DACGDM010000000
VERSION     DACGDM010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.211"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            138..752
                     /locus_tag="IXR05_002933"
     CDS             138..752
                     /locus_tag="IXR05_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261357.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(776..1126)
                     /locus_tag="IXR05_002934"
     CDS             complement(776..1126)
                     /locus_tag="IXR05_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4261358.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1120..1383)
                     /locus_tag="IXR05_002935"
     CDS             complement(1120..1383)
                     /locus_tag="IXR05_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAQ4261359.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
BASE COUNT          521 a          286 c          245 g          526 t
ORIGIN      
        1 atactatttc ctccatcatt agtttttgtc tatataaggt ataccctaac tagacacgac
       61 cgcgacattg aaaaatctgg ttttctcgtg tatgattagg gtgtttttta aatagttgca
      121 gaaagtaggt aaaaattttg agagttgcat acatacgtgt ctcatccatc gatcaaaatg
      181 aacaacggca gattgaagaa atgaaaaaat tcggtgcaga gagaattttc attgagaaac
      241 aatctggcgc aacgattact catcgacctg tttttcaaga agcactggat ttcgtccgag
      301 atcaagatat ttttattgtg gaagctattg atcgacttgg aagaaattac gacgagatca
      361 tcgcttcagt caattacttg aagaagaaaa atgtgcagct gatcatcaca agtctaccga
      421 tcatggccga agcaattggc aatcctctcc tggataaatt cattaaagat ttgatcattc
      481 aaattttggc catgatcgct gaacaagaac gtaccgaatc taaacgacgt caggcacaag
      541 gcattaagat tgcaaaagcg aacggtgttt ataaaggacg tcctaagcta tacagtgcca
      601 atgcaaaaga tccccaacgt cgtcttgttt ataaaaacat cgttgaggat ctaaaaaaag
      661 gtgttgcgat cgctaagatt gcaaaagact acaatgttac gagacaaacc gtatatagaa
      721 taaaaaaaga cagcatggtc aatcacgaat agttgatcat gctgctgttt ctattttatt
      781 tgcttacttt ttgaaaaact gttctaactt tcatcaataa ctcctcaact aaactatcat
      841 gcgctttttc caaaaaaata cactctctgg cttcataatc aattgtcgtt agttgatcta
      901 ataatacttt tcctgttgtc ttcatttcat attctgagtt tatatttaca tatagcggat
      961 agtttctagt tgtactagaa attggagcaa ctgtaacaac gttactataa tccgcaataa
     1021 tatcatgact taaaacaata taaggtcttt tacctgtctg ttcgtgtcca gatcgaggtg
     1081 ctgtattcaa taatagaata tcgccttgtc taggttttct caccattttt cattacctac
     1141 tgcttcacct aaattttgaa tcgtcacatg atttctttca tcagtgtaat tttcaaataa
     1201 ctgttcaatt gttaattcat tttctatatt agccgcttcg ataattagcc gcttctgacc
     1261 gtttacttct tcttgtatta tcttcacttt gtcttctgta tgaattccaa gatattccat
     1321 aatatacttt ggcaatctaa ggccattact atttccccat ttttttatag gtaacatttc
     1381 catagtagac acctctttct gtatatacat agtataacat acataagaaa aaacgtatat
     1441 acttaattat ccttttctat taaattagat taacattcca tgaatccata aactatgtta
     1501 acatttatat gaaaatagtc gaaaggaaat cataatatgt ttaagaaaac aaaatcttta
     1561 gaatcaggta agaaaaaa
//
LOCUS       DACGDM010000204         1573 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.212, whole genome shotgun sequence.
ACCESSION   DACGDM010000204 DACGDM010000000
VERSION     DACGDM010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.212"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
BASE COUNT          594 a          179 c          320 g          480 t
ORIGIN      
        1 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
       61 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      121 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      181 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      241 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
      301 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
      361 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
      421 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
      481 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
      541 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
      601 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
      661 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtcttaa atcattgtta
      721 tgaaaatgga ttaaaagagt tcatcaaggt gtgattaaca agttactttt cattacatcg
      781 aatttttcag aagttgctta tattggtgat gatattaatg atttatcatg tatgacatct
      841 gtgaagaagc gggaggaata gtagaatgtc caaaaaatgc cacaagaaat gagattgaat
      901 tatctgattt tattgtaact cacagtggtg gtgacgaatc tgtgatagag tttattgagt
      961 ggatattgga atcgatatag tgtagtagta cagaaaaatt atcatacaat taatactagg
     1021 cataagaata ttggcatatt ctagagttaa aagtaactat tcgaaaagga taaggttaga
     1081 attttttgtt ttgccagtgg aagaatataa aaagggcatt ggaaattaat atattagaat
     1141 gctaagcgga gaaaaaaata tatgaaaagt acgtccttgt gatgggatgg aaaaatacac
     1201 ttatttcaaa caacgataat ataattatgt gaaccgaagt atactcgctt ctaattcaat
     1261 cctcaaatcc cgacagtcgc gacttcaaaa aagcgtatag ttttaatgta tccccatatg
     1321 atccgaaaaa tggtaattta caattaacag tttgatgatg ttgaagatgt ggaaatgctg
     1381 aaattaccat gatgagaaac acattaatta aagggaatta attaactaga atataatctg
     1441 attcaatttg aattaagcaa aaaaaggctg agttttaaat aatcgcgaat tgtaaaatta
     1501 agttagaaaa ataaaaaggc atttatggta cactcaaatt gtatttccga cgaaagaaaa
     1561 caaaggagtg taa
//
LOCUS       DACGDM010000205         1516 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.213, whole genome shotgun sequence.
ACCESSION   DACGDM010000205 DACGDM010000000
VERSION     DACGDM010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.213"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..354
                     /locus_tag="IXR05_002936"
     CDS             <1..354
                     /locus_tag="IXR05_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4261360.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
     gene            355..903
                     /locus_tag="IXR05_002937"
     CDS             355..903
                     /locus_tag="IXR05_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261361.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            1163..1516
                     /locus_tag="IXR05_002938"
                     /pseudo
     CDS             1163..1516
                     /locus_tag="IXR05_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          600 a          184 c          325 g          407 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacagagtag aggaagaaca
      541 aaaaaagttg gcgcaccaat cagaaagttt gataaggttt attccaccaa gcatccttta
      601 aaactgtcga ctttgttaaa tgcgacttcc agagttttag tagaaaagta tgagactaat
      661 atgacaagag atgaattgct tagaaaagct ttagatgagt atattaaaca gaatcttacg
      721 caagaagata agcaagattt gtttaatgac gtggtgaaag aactagactt gttcagagaa
      781 aaatatccaa ttgttccaga attagatgat cgtggagaaa taataagaac taccagtcag
      841 ataaaacaag ataccgaaga ctcactgcgc aaagggtggg gaatgaataa taaagttaga
      901 taataatcaa agaagaacta agtaactacc tttaaacggt agttacttag ttcttctttg
      961 atttgcatga aatagagggg atttattttt ctggttacgt gattaaaaaa tccaaaaaat
     1021 gagcatagga acggttatga ttttagggtg tgttttaatg agatattgtg atttcattaa
     1081 caagtgtatg ataatctgtt gttgagttag taaataagta atagagctaa ctctaaaata
     1141 aaactattag gaggagatgt aggtgaaaaa gtttaaaaag aaaatatatt taggattggt
     1201 tgttggggtg agtatgtttg ggttcatggc tcatactaaa caagtaactg cagatactaa
     1261 ccaaaaagaa aggattatga gccaattaga tgactctcaa ataagtatgt acccaatgag
     1321 ctaattgtca gtttaaaggc tacacaaaga atttcaacag agaaaaataa accgcaaaat
     1381 ttattgggtg taaaagttat ggtggaaaaa gatttgactc ttaggataaa tgaaagcgat
     1441 tataataagc gagatcaagt attattagtg aaattgaacg aagaaattag tgtggaagag
     1501 gcagtaagaa cattta
//
LOCUS       DACGDM010000206         1509 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.214, whole genome shotgun sequence.
ACCESSION   DACGDM010000206 DACGDM010000000
VERSION     DACGDM010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.214"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            101..868
                     /locus_tag="IXR05_002939"
     CDS             101..868
                     /locus_tag="IXR05_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4261362.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            1060..1458
                     /locus_tag="IXR05_002940"
     CDS             1060..1458
                     /locus_tag="IXR05_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAQ4261363.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
BASE COUNT          561 a          189 c          282 g          477 t
ORIGIN      
        1 aatactgtta aatatctcga aaaatcaatt acgagttatt tgccttatgt gaacctttat
       61 gattaacaac tgaaaaaatg cgtgaaggaa ggaaaaactt ttgaaaaaag atgaactgac
      121 aaagtacaat gaggagttct tagcaacaat tgacatgaaa atggatttaa agtcgtatga
      181 actttatcaa ttgctgttca gttatatctc acccacaaag ctaaagaaaa caggcgtagt
      241 agatttacct gttaaagcga ttattaatta catggatgtt gatcaaaatc ttgaaacgga
      301 actaaaaacc atagttaaca ctttgcaaag acaagcagtt tatgaaattt cgaatctaga
      361 caaaaaatat aagacgtata ctactgtatc tgctattgat cggattcatt gggatttaga
      421 agagcatagt gtatctttca gtttttcaga agatgtaatt cccttaattg tctcaatcaa
      481 aaagaagtat ccgttctttg tttttgaaga cttagcatct tttcaaaaaa aatatagcat
      541 cgtgttatac aaatatttgg cgatgtatta taaaaaatat cttatcgcca aaaataaagg
      601 agattttgag aaagctgaaa tatataagaa tcccctgatt gaaatagtta aaattcgtga
      661 gattacgaaa acagaaaatg agtataaaac aatatcgaat tttgatagac gtgttttaag
      721 ggaatcagtt gaggaaatta atgaaaaatc aatgctgaat attgattttg ctaaagttag
      781 aaaaggcaga aattacaatt ttgctgtcca gtttaatatt tctagtgagt ttgatgaaaa
      841 aacttataga gaaaaaaaat taggttaatg caaaatatat cttactcgtt tgaagatgct
      901 tcagacgtat gctaagatat atagtgcctt gggagcaagg tattaatctc ctttagaggt
      961 taattagctt gtgatcgcct atcaattttt ttggtaggcg attctttttt ttgaaacaaa
     1021 aaagcaaaaa ttatttttta attagagagg tgcaatgcga tgaaatactt tttttgtgca
     1081 gtattcgaat ggaaaggaaa tgaatatgca gttaaattcc cagattttcc agacttatat
     1141 acacatggtg aaactttaga agatgctttt gagatggcgc aagaagtatt ggaaggatac
     1201 ttggtgcttt tagagttgca agaaaaagaa attccatcgc ctacgcctgt tcaagagtta
     1261 aatgcaagaa tcaagcgatc tgagaatgtt aatttatttg tcgtaaaagc taatacgaaa
     1321 gttgctaaag ctcgaaacaa gcaaaattat gatcgaaaat cagtgactgt ggaacactat
     1381 ttaaatgttt tagcggctga agagaatatt aatctgtcga aagctttgaa tgatttgttg
     1441 agagaaaagt tgatttgatg tctctcagat gatcatatta agcaaaaaca gcttgtttta
     1501 ggacgtatg
//
LOCUS       DACGDM010000207         1467 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.216, whole genome shotgun sequence.
ACCESSION   DACGDM010000207 DACGDM010000000
VERSION     DACGDM010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.216"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..493)
                     /locus_tag="IXR05_002941"
     CDS             complement(<1..493)
                     /locus_tag="IXR05_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4261364.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLE"
     gene            637..1413
                     /locus_tag="IXR05_002942"
     CDS             637..1413
                     /locus_tag="IXR05_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4261365.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
BASE COUNT          491 a          220 c          270 g          486 t
ORIGIN      
        1 cttcgagatg accaaattct ttagtcaggt gtggatagag actgttccgt tcatgaatcg
       61 ttctgcgaaa ggcctgtttt ccacgctttt cttgatgatt attcggttta cgtttcccct
      121 tcataggtaa cgactgtgtg tcaaaaaggc cttttttaaa catccgatag agtgtacgaa
      181 cagaacaatc aattggaaac tcgccacggc cgataatcac atcgggtgac catccttgag
      241 ctaccttttc ttgaacatat gttgattgtt catcagataa aacggttgaa cgtcgtccac
      301 aacgagattt attttgtttg tattgacggt aataatctag cacttttttt ccttgtttga
      361 gaaacgaata aacattataa atggtttgtc tagagcgatt taaactttgt gcgacaagag
      421 cgacaggttt ctcgatattg aaataagact ctatgattac tagttcgtct gttgtaagat
      481 gggtgtaagt catttgtact cactccttat taattctttg gtcggaacta ttttgagtgt
      541 agcacaaatg atctttttag ttgtctagct taattttaca atcgacgttt taataaattg
      601 tgatataatg aagtataact ttttagggag tgtactatga attttcaaga taatagacca
      661 ttatatttac aagtagaagc ttctatacgt aacgatattc gtgaaaaaaa atatcttcca
      721 ggagagcaat tacctacaga agaagaatta tgtaaaattt atggagtaag taagattacc
      781 attcgaaaag cttttaaact tttagcagaa agtggaacag ttgaacgatt aagggggaaa
      841 gggacctttg taactcaaaa aaaagaaagt ttaaaattag ctggagttca tggatttagc
      901 gattctcttt ctacccgagg acataaaatt agatatactg ttttacattc taaaattata
      961 aaggctgatg agtttttagc taataaatta caaatcaatg taactgatag agtttacaat
     1021 attaaacgtt taatgtggga agacggtgcc ccgatgggaa ttgataattt tttcgcatca
     1081 gaagaaaaat ttccaacttt atttgaaaaa ggtagccaat atacttcatt atataaactt
     1141 ctagaagatg actatgatgt caaagctacg agctctatta tggaaataaa cggtttatct
     1201 gcaacacctg agctttccga cttattgcaa tgtatagtag gagatccgct atttatttta
     1261 gaaaaggttg gcaaagataa aaataatcaa ccatttcatt attctcaatc cacagttcgt
     1321 tgtgatagaa ttagttatgt tattgaagtc acagaaaata tcactttaga tacggtgcat
     1381 aaaaatgatt cagatcctaa agtaatagat tgatattaaa agaaatcata cccaaagcaa
     1441 tcaattttga ttagatttgg gcatgat
//
LOCUS       DACGDM010000208         1462 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.217, whole genome shotgun sequence.
ACCESSION   DACGDM010000208 DACGDM010000000
VERSION     DACGDM010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.217"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(20..1051)
                     /locus_tag="IXR05_002943"
     CDS             complement(20..1051)
                     /locus_tag="IXR05_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4261366.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          443 a          236 c          250 g          533 t
ORIGIN      
        1 aaaagatcat acatttgttt tatatggaag aaacccgaac gaatgccgct aattcgtgat
       61 aagaaaaatc aaccatcttt tcccagatat cttgaaaaga atgggatgag aggtatcgat
      121 taccacataa ataatttacc gcgtcagcat catctaaata tagttctgca taataacgat
      181 atgtttttct gcatagttct ggcgatacgt ttttatatac tgtaattttg ctcaaaattt
      241 ggcgaatagt ccgaggagaa atttgctgat catgtgagga acgaaaaaca aaagaatttt
      301 cgtccgtatt ttgtgctgtt aacttaaaat agttctccag aaatggcatc gcttcttttg
      361 gtattggtac tttattcagt ctgttttctt ttctattcag attaagaatc tgcttggtca
      421 aagatacatc tttacgttta agttctacta cttcatggat ctttaatccg caatacagaa
      481 gaatggcagt aattgcaagg ttcctcggtc tattcttttc ttcaaagcta gcttctctgc
      541 ttgtttgaaa gccttcaatc gggataaaca aatgctcaaa atctttgaaa agttctgcat
      601 cgatatatcg cggagctgct ttggttgttt ccggtaaact tgtacccaaa agagaaatct
      661 cttcttcaat cagtcctttt tgatacaaaa atcgtaaaaa atgatttaat gaatattgct
      721 tccttgaaat cccgtaatag ctattttcaa acaattgctc cgtttcttgg ttcgctgtag
      781 tttggaacga acgagtatgt cgatagattt tagctaagaa attctgataa tcttgttttt
      841 ctaaatggat aatcagctga tcatccactt cttcagaaaa tacttttctc aaataatcag
      901 taaacagatg aaaatctttt gcgtattcat agcgactgcc taatgaaagg gaagaacgat
      961 tttcttctaa aaactgttga aagacggaag ggagcaagtg tgtacgttgc tttaactttt
     1021 cttgcagttg ttttctagtt ttgctgtcca ttacaaattc cctccaatag tgttcatttt
     1081 ctatatttta ccgcatttca tcaaatgaag atagacagtt tgtcttgatc ttaggaagca
     1141 aatttttaac taagtactag ctaaaagata tgaagtaaga agatacattt ttagttattt
     1201 tattagtgca gtcattcttt tgatctttta attgatttat cctcttttta gctatgtggt
     1261 tacttcatga gcaatgaaat ggatttggtt cgttctaatg gcaggaggct ctttctttta
     1321 tttccgaaaa attagaaaac attttttcag aatcgattgg ctctccattt attcaataat
     1381 ggtttgtcta acgatattgt tgggataatt cttaaagaag tattagaaat agttggtact
     1441 tcattacttt acatgaagat tt
//
LOCUS       DACGDM010000209         1453 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.218, whole genome shotgun sequence.
ACCESSION   DACGDM010000209 DACGDM010000000
VERSION     DACGDM010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.218"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..625)
                     /locus_tag="IXR05_002944"
     CDS             complement(<1..625)
                     /locus_tag="IXR05_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAQ4261367.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFD"
     gene            complement(784..1050)
                     /locus_tag="IXR05_002945"
     CDS             complement(784..1050)
                     /locus_tag="IXR05_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261368.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(1040..1396)
                     /locus_tag="IXR05_002946"
     CDS             complement(1040..1396)
                     /locus_tag="IXR05_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4261369.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT          406 a          279 c          181 g          587 t
ORIGIN      
        1 gatcaaaaat atctaagttg tcatcaaaat ctttatcagt tccggtaact tttttgttaa
       61 ttactgaagg tgtcttgtaa gaaatagaat ctaaatcaaa gcgttttgat tctaaattat
      121 tttgtgcttt ctcaattaaa taattcactt tttttgtgag aaaccttctg atattgtctt
      181 tgctatatgt tccataaaaa cccttatctt ctaaagagtc cctgtacttc ttaacttcta
      241 tatactcttc agccaaaact tgtggaactg gttcatctaa gaaaaaaacc cctacctcgc
      301 ctttgctatt tttataaaag taatcaattt ctgctatagt tcccgatcta taattatcaa
      361 ctggagaacc caacttatgg ccaaaaatcg ctaataatat atcactattt tctacaattt
      421 gtttattaat aacactttgc ccagagctat tatttatata agtaggaatc gcattcgttt
      481 cccatcgaat tggcatcaaa attacttttg tattatctgt attttctata ttccatctat
      541 atatggtttc ttctacttca ttcctctttg ctgctatatc acctggtgat gctataaata
      601 cttttattag atttatggtt ttcatttatt gtacctttct ctttatgtct ctttaaagta
      661 atttttgtat aaaatttatt gacttttaca ctataggaca acttttatct atttagtaca
      721 aaaaggccca ctaaactaat tgattagtta ggagcctatt acaggtatat tttcaactcg
      781 cttttaagca aattctacta ccagcttttt gcctaatgcc ctagcgatat catcaagttt
      841 atcgaaagat acgttatccc ctctctcaat tcgagcaata gtagattgag ttgtatgtgc
      901 tttttgtgca agctccgctt gagttaggcc tgcttcctcc cgtgcatgat aaagagcaac
      961 cgcagtttcg agttttcttc cttcacggtc atatgcttct gcaaaatctt tgtctttttg
     1021 cttttcttca atcaattttt taatcatcat ttgtgaacca ctcctctcta agttcttttg
     1081 catgtttaag ttcacttatt ggtgttttct ccgttttttt agtaaatcca tgggtaatga
     1141 cataccttcc attgaccaca tggaaataga tagctctttg gatgtttgat cctaccttac
     1201 ttcttaattc gtacaaatta gtgtctaatt ttttcaccca tttcaaccgt tgagctacta
     1261 gcatcccatt cttttctgtt tcttctattg tacgtaaaag cttcgcacta tctttttttg
     1321 gtaatgtttc caaccattct aaaaattcat catgaccatt aggtctttta aatgtttcaa
     1381 aagatatttt ttccataccc aattatatca tatattgatt ttatattata gtatataaca
     1441 taaaaattcg aat
//
LOCUS       DACGDM010000210         1440 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.219, whole genome shotgun sequence.
ACCESSION   DACGDM010000210 DACGDM010000000
VERSION     DACGDM010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.219"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            105..1406
                     /locus_tag="IXR05_002947"
     CDS             105..1406
                     /locus_tag="IXR05_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4261370.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          474 a          288 c          264 g          414 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
//
LOCUS       DACGDM010000211         1439 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.220, whole genome shotgun sequence.
ACCESSION   DACGDM010000211 DACGDM010000000
VERSION     DACGDM010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.220"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..626)
                     /locus_tag="IXR05_002948"
     CDS             complement(<1..626)
                     /locus_tag="IXR05_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4261371.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
     gene            914..>1439
                     /locus_tag="IXR05_002949"
     CDS             914..>1439
                     /locus_tag="IXR05_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4261372.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYV"
BASE COUNT          495 a          211 c          273 g          460 t
ORIGIN      
        1 tttctaggaa agcgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gatgggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcta tgagaatcgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtctgccca
      361 caatcatagc atagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      421 ttcaatatct gagtacgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      481 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      601 agtaattttc tagtatgatt atccatagag cgactccttt ggtagggtga tgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      721 gaaaatcgcc ttcgattttc caacaacaca aaatattata gaacccttta ttctaaagga
      781 tttcaaggtg tctgtttgca tttattagaa aaaagaaaaa gtattggcaa cagaaggtgt
      841 caccaacact agatattata gagccataat atgctgtata atatctagtg tataggctta
      901 agtggaggta tatatgaaaa tattaactgt tgaagatgat aatatgataa gagagggaat
      961 aagtgaatat ctttcagaat ttggatatac tgttattcaa gctaaagatg gaagagaagc
     1021 cttgtcaaaa tttaatagcg atataaattt ggttatctta gacattcaga taccttttat
     1081 aaatggttta gaagtgttga aagaaattag aaagaaaagc aatttaccaa ttctaatctt
     1141 gactgcattt agtgatgaag aatataaaat tgatgcattt actaatttag tagacggata
     1201 tgtagaaaag ccattttcat tgccggtctt aaaagctaga atagattctt taattaagaa
     1261 gaattatgga catttagaga agtttgaata taaggatcta tcggttaatt ttaatagcta
     1321 tacagctaaa ataaatggtg aagaaataga tgtaaatgca aaagaactag aagtattaaa
     1381 atgtttattg gataataatg gacaagtgtt aacaagaatg caaattattg attatgtat
//
LOCUS       DACGDM010000212         1422 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.221, whole genome shotgun sequence.
ACCESSION   DACGDM010000212 DACGDM010000000
VERSION     DACGDM010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.221"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..383
                     /locus_tag="IXR05_002950"
     CDS             <1..383
                     /locus_tag="IXR05_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAQ4261373.1"
                     /translation="ELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENEVTIVNKSR
                     YTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDIDSEEDFKWL
                     EFLFPKFLEDSSELQDIYNYLYRR"
     gene            388..1335
                     /locus_tag="IXR05_002951"
     CDS             388..1335
                     /locus_tag="IXR05_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAQ4261374.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          481 a          201 c          286 g          454 t
ORIGIN      
        1 aagaattaat agatgaacat ctaaaaaatt tagataaaga cgtctacttt tcagttgttt
       61 ctgcaagacg taatccctat tttaatatgg taaaaagaat tgaaaatgaa gttactatag
      121 ttaataaatc aagatacaca tctaggcaac agacacctga agtttttgaa atgaatgcct
      181 caatgtattc ttttaaacct gaatttctaa aaaaaagtaa ttatattttt gatgggcaat
      241 gtgggataat aaaaatgaga gattatctaa ttttagatat tgatagtgaa gaagatttta
      301 aatggttaga atttttgttt cctaaatttt tagaagattc ttcggagctt caagatatct
      361 ataattattt atatcggagg taaaaggatg agctgttatc ttatcaccgg tggggctggc
      421 ttcattggtt ctaccttagc caatcattta ggagaagaac atgtggtaat cgtcgtcgat
      481 gacttatcaa tgggaaaagt agaaaatctt gatatgacga aaaatatcac ttttattgag
      541 ggagatgtcg ctgagaaatc cttgatggaa gagatcatga aagctaataa atttgattat
      601 atctttcatt tagcagcagt tgctagtgtg gcagattcag ttgcccgacc agtagaaaca
      661 catcgtgtga attttgaaag tgtattaatg attttagaat tgatccgcaa gtatcaacct
      721 gatttaaaac ggatcgtgtt tagttcttca gcggctgttt atggggatga accgacttta
      781 ccaaaaaaag aagagtccgt gattcgccca ttgacgcctt atgcggttga taaattcgct
      841 gcagaacaat atgtgctaga ttattgtcat ttatatgatg tacccggtag cgcagttcgt
      901 tttttcaatg tctatggtcc aaatcaaaat ccgaattctc catacagtgg tgtgatttct
      961 attctcgtag atcgctataa gaaacaaatc gtaggagaag caacttcatt tacattattt
     1021 ggtgatggaa gccagtctag agactttgtt tatatagatg atgtaatcca agcattactt
     1081 ttagttgcga atgaggaagc tgcactgggg aaacaattca atgttggaac gggtaaagca
     1141 accacacttt tggaattgat tcatgcaatc aatgaaattc tcggtgtaga attgacactt
     1201 gaatacaaag aagagcgttc gggtgatatc catgactctc tagcagatat tactaagatc
     1261 cagtcaattg gctatcaacc gaaatatggt attttaagtg gaatgactaa ttatttgaaa
     1321 actgaaatca attaaaacat actaagataa gattagaggg taaattcagg ctctttgtca
     1381 ataaggactg atgagttttg taaaatcaaa tctgggatag aa
//
LOCUS       DACGDM010000213         1417 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.222, whole genome shotgun sequence.
ACCESSION   DACGDM010000213 DACGDM010000000
VERSION     DACGDM010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.222"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(150..1337)
                     /locus_tag="IXR05_002952"
     CDS             complement(150..1337)
                     /locus_tag="IXR05_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAQ4261375.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          412 a          308 c          249 g          448 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttc
//
LOCUS       DACGDM010000214         1385 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.223, whole genome shotgun sequence.
ACCESSION   DACGDM010000214 DACGDM010000000
VERSION     DACGDM010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.223"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(322..936)
                     /locus_tag="IXR05_002953"
     CDS             complement(322..936)
                     /locus_tag="IXR05_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4261376.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT          453 a          269 c          230 g          433 t
ORIGIN      
        1 ggggaagact ctttcatcaa cgtgtattaa gagacaagaa agaatccata tggattcttt
       61 cttgtctctt tttccactac tttttatttt tctgacacta catattctta taactcattt
      121 ctcataactg tgaaacaact tataaaaata acaaacttta aacaaaacaa gcttaaaatc
      181 aaagatgatc catcttaaaa taactaaaac aaaaaaagta gtcgttgtta atcctcatta
      241 ataatcgttt tctttttttc aaacgctcca tttttatgtg gaacattatt tttttaagga
      301 actttgtcaa catgtggata actattttcc acttgtgtcc tggactagct gttttgctgt
      361 aaaatacaaa acttgctgca gcaaaaagat cgttgcaaga gaggctgttc cgcagatcgc
      421 tggatctaga tttggcaaag tcaagactgc atcatgtaaa ttggcgtggt tgtccaaaac
      481 caaatcagca aattcaaata atcgcaaacc actgctatgt tgcgatttga tacttcgtga
      541 caaatcaaat ccagtaacaa tgattaatgg atgaccattt tctttgatcc actgagctag
      601 ttcgatgatt gccgggtttc ttccttcatt cgaaagaaga agaaaaatgt cttctgattt
      661 gacagaaagc tgatcaataa ttgcctgtcc tgcaccttct agcgtttcat agacacctcc
      721 ggctggattt tcaatcaata tacttggtac aagatccggg gtttgatccc aaaattcaaa
      781 tgctacacca cttagtgtgc ggctagcata tatctgcaat ctaccacctt gattaatttg
      841 tttcgcgatc caagtgccag cttgaagcat cagcggctct tctatcctta atttctcttc
      901 caattggtga taatagtcaa aataacataa actcatttat ctctcccgcc tagctatact
      961 tgacatgaat agaaacagct gcctaatcta aggaagtaca taaaaaaaca gtagttagac
     1021 agtaacacat gtggtctttg ctgtttcaaa cacaaaaaag gcattgaacg aatacgccca
     1081 ataccttgac atagcaaata aaacaacgtg cagaccatgg aaaatatcta cataggggta
     1141 gaattttcac cctagattag gtacaataaa ttaggtcgat gcactgcatt gactatggca
     1201 aaatgatcgg tcagggtgta tgtgtgtgac tggtcattcc ctgattctta gcgccaacta
     1261 agggtcaggg agcctttttt tattcagctg tttctatctg aatttattgt aagtaatctc
     1321 ttatccaagt gcaagcaaga aaatacaaaa aaacattggt atgatttata tatatataaa
     1381 taaca
//
LOCUS       DACGDM010000215         1373 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.224, whole genome shotgun sequence.
ACCESSION   DACGDM010000215 DACGDM010000000
VERSION     DACGDM010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.224"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            191..445
                     /locus_tag="IXR05_002954"
     CDS             191..445
                     /locus_tag="IXR05_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4261377.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="IXR05_002955"
     CDS             446..763
                     /locus_tag="IXR05_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4261378.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          493 a          196 c          266 g          418 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaagacaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accttaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acttccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat ata
//
LOCUS       DACGDM010000216         1314 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.226, whole genome shotgun sequence.
ACCESSION   DACGDM010000216 DACGDM010000000
VERSION     DACGDM010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.226"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..848
                     /locus_tag="IXR05_002956"
     CDS             <1..848
                     /locus_tag="IXR05_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4261379.1"
                     /translation="EIADLIEKMYGHHYTPQTMSNITKSFTEEVTAFKGRELHDRYAA
                     IYMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQER
                     GLKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVFRNISHKVRVNNRKEVCDDFKM
                     VYQASSKEVALEARGAFAKKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLI
                     ESFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLS
                     QPMEN"
BASE COUNT          429 a          240 c          254 g          391 t
ORIGIN      
        1 ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca caaaccatgt
       61 ccaatataac aaaatcattt acagaagagg taacggcgtt taaagggcga gagcttcatg
      121 accgttatgc tgctatttat atggacgcaa cgtatattcc gttaaagcgg aaaaccgtcg
      181 ccaaggaagc tattcatatc gcagttggca ttcgcccgga cggatcaaag gaagtattga
      241 gctatgcgat tgcaccgact gaatccatca cgatttggga ggaaatttta ttagaccttc
      301 aagagcgcgg tttgaaaaat gtcctcctgt tcatcacgga tggcttaaag gggatggtag
      361 gagcgattag tcggttctat cccaaagctc gttttcaaca ttgttgtgta cacgtttttc
      421 gtaatatcag tcacaaagtg cgtgtcaata atcgtaagga agtctgtgat gattttaaaa
      481 tggtgtatca agcctcatct aaagaggtgg cgttagaagc acgtggtgct tttgcgaaaa
      541 aatggaaaac cagctatcca aaagtggttg aatcgattct ttcgaacgat cacttgctca
      601 ctttctatga tttccccttg gccatacgca agagtattta ttctacgaac ttgattgaat
      661 cctttaataa gcaaatcaag aaatacagcc accgcaagga acagttccaa aacgaagagt
      721 cgatggaacg tttcttagtc tcgtcttttg atacttacaa ccaaaaattc ctaggtcgca
      781 gtcataaagg tttccaacag gccgaaggcg agctcgaaca aatgctgagt caaccgatgg
      841 agaattagaa acaatctaca gtagggaaga accatttaca caaaattatt gacgctccca
      901 agctaaaact cctattaatc gatctactaa aaataaataa aaaaattctt ttcaattttt
      961 atttatggta tgacataaat aaagtaaagt tattcttcta ggttaatctt attaatactc
     1021 tttctcacta gtgttgcatg caacactagt gagaaagagt attaaatata ctgcaaggca
     1081 agacatttgg taattgaaga ataacaagca aaaaaatagc agtcaggtct cttgacaaag
     1141 tatagttgct attctttttt taggccctac tttaatgaaa tttttgtttg gagggaacga
     1201 cttcattcct ttgattattt cagttgaatt taatagagaa gcctggcgtc tattaagaaa
     1261 tacttttctt gatgagcgtc aattttttta acggaaatct atcctatact aaat
//
LOCUS       DACGDM010000217         1312 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.227, whole genome shotgun sequence.
ACCESSION   DACGDM010000217 DACGDM010000000
VERSION     DACGDM010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.227"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            82..>1312
                     /locus_tag="IXR05_002957"
     CDS             82..>1312
                     /locus_tag="IXR05_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HAQ4261380.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYG"
BASE COUNT          442 a          250 c          253 g          367 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atagaagcga agaataccca tataaagaca atgaaacgag tatcctacgg at
//
LOCUS       DACGDM010000218         1247 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.228, whole genome shotgun sequence.
ACCESSION   DACGDM010000218 DACGDM010000000
VERSION     DACGDM010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.228"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            119..991
                     /locus_tag="IXR05_002958"
     CDS             119..991
                     /locus_tag="IXR05_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4261381.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          382 a          230 c          285 g          350 t
ORIGIN      
        1 tcaaaaagaa aaaatagtag ttatttactt gtcatgttac taaataaaaa aataatttaa
       61 atatgatata tagtcattta tttagtgatt tcattctaaa ataaagggag aaatgtctat
      121 gctatacggt gcaattgaag caggcggcac aaaatttgtg tgtgccattg gcgatgaaga
      181 aatgacgatc aaggaaagag tgagctttcc gacaacgaca cctgaggaaa caatgccttt
      241 agtcattgac ttcttcaaac aataccaagc agatttagca gggattggga ttggctcatt
      301 tgggcctatc gatatccatc gcgattccgc cacttatggg tacattacct cgaccccgaa
      361 attggcatgg caaaattttg atttcatcgg taccatgaaa aaagaatttc cgatcccgat
      421 ttcttggaca acagatgtca atgcggctgc ctatggtgag tatgtcttcg gcagtggcaa
      481 aggattgagc agtgtcgttt actatacgat cggtacgggt gttggcggcg gtgccttaca
      541 agaagggcgc tttatcgaag ggtttagtca tccagaaatg gggcatatgc tcgtcgtccc
      601 tcatccaaaa gatgactttg ctggcagctg tccatttcat ggcaactgtt tagaagggat
      661 ggccgctgga cccgccatcg aaaaacgctt agggaaaaaa ggacaagagg ttgcagaaga
      721 tgatccttat tgggaaatcg aagcctccta tattgctcaa tgtgcctaca atacaacctt
      781 gatgttttct ccagatgtga tcatttttgg cggtggtgtg atgaaacaac gccatatgct
      841 gcaaaacgtc cacgacgcat ttgcaaaatt ggtcaatggg tatgtcgaaa cacctgagtt
      901 aagcaaatat atcgtgaccc cagcattaga agacaacgct ggaacgctcg gttgtttggc
      961 attggctcga gaagcggtct tacattcata aacgaaaaaa ggctcttcga catttagtgt
     1021 tggtagagaa agatacaact gaaaatttag tcataaccag ttaggcagag tgcttaactg
     1081 gtttttgttt tacttggaag atcaagcctt gaatgagata aattcttgct cgaaagttat
     1141 ggaaatttcg atagccgtag gccacttgta ttgtgcaata gttttttaca cgccgtttgt
     1201 ataattaagc gagacaaata aaaaagccat ttatgttaca ctcaaat
//
LOCUS       DACGDM010000219         1246 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.229, whole genome shotgun sequence.
ACCESSION   DACGDM010000219 DACGDM010000000
VERSION     DACGDM010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.229"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            200..742
                     /locus_tag="IXR05_002959"
     CDS             200..742
                     /locus_tag="IXR05_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261382.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            832..>1246
                     /locus_tag="IXR05_002960"
     CDS             832..>1246
                     /locus_tag="IXR05_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAQ4261383.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DACGDM010000220         1245 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.230, whole genome shotgun sequence.
ACCESSION   DACGDM010000220 DACGDM010000000
VERSION     DACGDM010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.230"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..1244
                     /locus_tag="IXR05_002961"
     CDS             <1..1244
                     /locus_tag="IXR05_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAQ4261384.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          410 a          222 c          268 g          345 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaa
//
LOCUS       DACGDM010000221         1244 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.231, whole genome shotgun sequence.
ACCESSION   DACGDM010000221 DACGDM010000000
VERSION     DACGDM010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.231"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(68..991)
                     /locus_tag="IXR05_002962"
     CDS             complement(68..991)
                     /locus_tag="IXR05_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261385.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
BASE COUNT          401 a          219 c          128 g          496 t
ORIGIN      
        1 aaagaaaaaa gttgtgattt tggaaatcac aacttttttc ttttacgata aatcaatcct
       61 tattaaatta tttaggaaaa tattgttcaa ttatttcttt atatattttc tcatagtatg
      121 tttctgtcca tcctaatgtt cctataaaat caagtcctct acattttaaa ggttcactta
      181 aactattaat atagttaata atgttgtcta tccttttctc tttatcttca ccttcaatct
      241 ggggagcata tagtccaatt tcctcccaat aatatgaatc tctttcaatt cccatgatgg
      301 tagctttggc taatttcaaa tcaaataacg attttagaat tcttagtgtc tcaataaagt
      361 cttctctctt caactcttta atccattgtg aattttctgg attatctaaa atttcaagtt
      421 catcttcatt ataagtatat ttcaaatttg acttgcttaa ctcatagata aatgaagttt
      481 cttgactcat aattctttta agtacttgac tataagtttc gtttgacttt gcccatttcg
      541 ctaattctac cactgtattc actaataaat cgaaataatg atgttctcgt tcaatagtct
      601 cagcattttg aaaatgaaaa tcacctttat aaactccatt cttttccact gttttattaa
      661 tattttttaa aaaccagaat gagtttgcaa atttagtcgt actttttcga ttaactaagt
      721 taataactct tccatgtaat aataagacaa aaatacataa atttttagct tccttattat
      781 tagatactaa ttgatcaatc atagggagcc attttttgat tttcactaat tgattgctca
      841 taaatctttc actggacttt tgttcaatct taaattgcaa aacttctaac tcataattcc
      901 catcttctga tttatttttg ggaacaacta tcaaactttt ataaagttta tccacatcaa
      961 aatttatctt ttttgcataa tttgtagcca ttaatacatc tccttattca taataaattt
     1021 catatgacgc tcctctcaaa atttaccggt agactagaaa aaagaataaa agatacgtca
     1081 attcacactt tattcttaaa aaaaaactgg tctctctacc ggtaatatcg attgagtccg
     1141 cctttatcga ctttatcctt tttttatatt aaattttttc accggtagac agggagagaa
     1201 agaataaact aaaaagccct taattcttaa tgttttcacc tcct
//
LOCUS       DACGDM010000222         1242 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.232, whole genome shotgun sequence.
ACCESSION   DACGDM010000222 DACGDM010000000
VERSION     DACGDM010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.232"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..724
                     /locus_tag="IXR05_002963"
     CDS             <1..724
                     /locus_tag="IXR05_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAQ4261386.1"
                     /translation="DFLSTPFDEESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGL
                     PVLLSTGMADIHEVSEAVDCFIDSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPV
                     GYSDHSLGYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTE
                     IFLGDGVKRAMPSELSTKEVSRKSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQ
                     YIGKKVKRPISADSVLLEEDVE"
     gene            721..>1242
                     /locus_tag="IXR05_002964"
     CDS             721..>1242
                     /locus_tag="IXR05_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAQ4261387.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAP"
BASE COUNT          407 a          166 c          270 g          399 t
ORIGIN      
        1 tgattttttg tctactcctt ttgatgaaga aagtgcagac tttctaaaac aaattggtgt
       61 acaaggattt aaaattggct caggagattt aacaaattta ccttttctta gaaaaataga
      121 tatgtatggg ttgccagttt tattatctac aggtatggct gatattcatg aggtcagtga
      181 ggctgtagat tgtttcatag atagtccagt tactatttta cattgtactt caaattatcc
      241 ggctagttct gaagatatta atttattggc gattaacaca ttaaaagaaa tgttcgggat
      301 acccgttggg tactccgatc attcattggg atatgatgtt ggtatttgtg ctgttgcgat
      361 gggtgctaag gtaattgaga aacattttac cttggataag gaactacctg gtccagatca
      421 taaagcttct ttagatcctc aggaatttgc agattttgta aagcatatta gaaacactga
      481 aatattttta ggtgatggtg ttaagcgagc aatgccttct gaacttagta caaaagaagt
      541 atcaagaaaa agcctagtgg tcactgagaa tttaaatgtg ggagatattc ttacagagaa
      601 atctcttaca ataaaacgtc ctggaaatgg aatagctcct aagtttttat atcaatatat
      661 tggcaaaaaa gttaaaagac caataagtgc agatagtgtt ctgcttgagg aagatgttga
      721 atgaaaaaaa tacttatagt aagtggaaca cgagctgatt atggaatata taaacctgtt
      781 gctgagaatt tactacaaga taattgggat gtatcatttg ttgtttctgg aatgcattta
      841 tcccataaat atggatttac taaagaattg atcttagctg acggatttag aattagtgga
      901 gaagttcaaa gtttgttttt agagaacaat aagggaaaca tggctcggtc tgtggcatta
      961 gagataaatg gtttcacaaa tatatttgaa caaactagcc ctgattttgt attattacta
     1021 ggggatagag gagaaatgtt ggcagctgcg atagcttgtt tgtatcttgg aatcaaaaca
     1081 gcacatattc acggaggcga agtgtctggt actgtagatg aatcaataag acatgccata
     1141 acgaaaatag catctgttca ttttgctgct acggaaaaaa gcaaagagcg tttaataaaa
     1201 atgggggaag attcttggag agtttttccc gtcggagctc ct
//
LOCUS       DACGDM010000223         1224 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.233, whole genome shotgun sequence.
ACCESSION   DACGDM010000223 DACGDM010000000
VERSION     DACGDM010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.233"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(226..1086)
                     /locus_tag="IXR05_002965"
     CDS             complement(226..1086)
                     /locus_tag="IXR05_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261388.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT          364 a          233 c          179 g          448 t
ORIGIN      
        1 tttgtgtgtt gcttatttcc ctctaactat cgttttctat ttgatggtta acctacttaa
       61 aataaatact gcaacgacaa acggagatca agcatgcttt gtaacgtatt ttacgataat
      121 tacgacttta ttttattact ctatcttgct gccatacccg tctatcccta atcatctttg
      181 gtgaattttt tcaaagttag cataacaaaa ataagtattt tttccttagt taatcaatag
      241 tatcattttt ttcatatgat ttaattcatc aattaatttt ttgtttttat taattttagc
      301 aaaagctagt gcatcttgaa tcaattcgag cacttctgcc ttcgacttat ttttagcctg
      361 tgcgttcttc gctaattggg cagcagctcg tgctaagtaa taagtcaaat ggttatccga
      421 acaaatatcg attgcgtaat ttagtagtgc atcacttgtt tccaaatcac cgtcttgcgc
      481 aaaaaaaaca ccacaatgaa agacgatatt taacacccgc cagatatctt ctgttgtacg
      541 aatcggatac gtataaattt tttcaaacac tcgattgaaa taaacttctg ctttttccaa
      601 ctctttttct ctagcataga ccattccaat acctgtatat gccaataaac gaaacaacgt
      661 gttggctgtt tctgccatca acaactgatc aaaatggaac aacacatccg taattggtgc
      721 attcgtaaaa atcatttcaa atccttttag atagtagtaa cgtgcaatca gctcagactc
      781 gtcaattacc ttgggatcaa tggctgctaa aatctgtgtc aattgttcat attcactcgt
      841 aatcagtgaa aactctgctt tttctagctg ttcatcaagt tgtgtattga tcacgttcat
      901 cgaagaaaaa agttcaacta acggaagatt gattcgatta cataatttga ttaaaatttt
      961 taacgaaggg acttgaccat tgttctcaaa tttacttaat gttgcttgtg tacaaattcc
     1021 ttcagacact tctttttgag ataagttggc agcctttctt gccgtaataa atttttcaat
     1081 gttcattatt ttctctccaa tcagacctca cacgaaaatc atttctgtct cgattttagc
     1141 atgttttctt tgggaatgct ttaggttctg ttgcaaagtt ttaaataaag aataaagtcc
     1201 cttacggtat ctatgattta agct
//
LOCUS       DACGDM010000224         1222 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.234, whole genome shotgun sequence.
ACCESSION   DACGDM010000224 DACGDM010000000
VERSION     DACGDM010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.234"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(61..279)
                     /locus_tag="IXR05_002966"
                     /pseudo
     CDS             complement(61..279)
                     /locus_tag="IXR05_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(545..739)
                     /locus_tag="IXR05_002967"
     CDS             complement(545..739)
                     /locus_tag="IXR05_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261389.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
BASE COUNT          432 a          205 c          167 g          418 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattgtac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta ttacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat ca
//
LOCUS       DACGDM010000225         1194 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.236, whole genome shotgun sequence.
ACCESSION   DACGDM010000225 DACGDM010000000
VERSION     DACGDM010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.236"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            122..457
                     /locus_tag="IXR05_002968"
                     /pseudo
     CDS             122..457
                     /locus_tag="IXR05_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            553..1194
                     /locus_tag="IXR05_002969"
                     /pseudo
     CDS             553..1194
                     /locus_tag="IXR05_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          453 a          219 c          229 g          293 t
ORIGIN      
        1 tttatataat aaaatgcaat acttttcgag agtgtaaaat attttgtgta aatagaaaaa
       61 aggaagtccc ttctgtagaa tagagttacc acaacacatt cacagaaaag aggacttcca
      121 tatgaacgat tttactacag aaattctaaa gactctagcg aacaaaggcg atttgaatga
      181 attattccgt gtccatttgg aaaaagctgt caatacgctt ctcaaaacgg agttaacggc
      241 tttcctcgat tacgaaaagt acgatcgcat tggttttaac acgggtaatt ctcgtaacgg
      301 ctcctatgac cgtacggtca agaccgagta cggggaactt catctccaga ttccgcgcga
      361 ccgcaacggc gagttcaagc aacagactgt tcctgcttat agacggacga atgatacctt
      421 agaggagacc gtcattcacc tcttccgaaa aggtatggat aggctacaat taactagtgg
      481 ataggctaca attaactaga cagaaaaatt aaggtgtgta gactagaaga aaacatacca
      541 ggaggaattt ttatgtctaa gagaacacga agaacttttt cacaagaatt caagcaacaa
      601 atcgtcaatc tttacttagc tggaaagcca cgtgtagaaa tcattcgaga atatgaacta
      661 acagcttcag catttgacaa atgggtaaag caatctaaaa cgagtggttc attcaaagaa
      721 aaagataatc ttacgcctga acaaaaagaa ttgttagaac tacgtaaaag aaaccagcaa
      781 ttagaaatgg aaaatgatat tttaaagcaa gcagcgctga tattcggacg aagagacaag
      841 taatcgatgc gaataagcat ctttacccta tatcagcgat gtgcagaata ttaggtctat
      901 cacgtcagtc ctattattat caatcaaaac caaagaaaga cgaatcagaa cttgaagaag
      961 tagtcgctga agaatttatc cgcagccgaa aggcctacgg ctcaagaaaa ataaaaaaag
     1021 ccttatcaaa acgaggcatt cagatcagcc gacgaaaaat tagtagaatc atgaaaaata
     1081 gaggattaaa atcgagctat actgttgctt attttaaagt acatcattct acttgcaatg
     1141 aagccaaaac gacaaacgta ttgaatcgta aattcttaag agacaaccca ttag
//
LOCUS       DACGDM010000226         1180 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.237, whole genome shotgun sequence.
ACCESSION   DACGDM010000226 DACGDM010000000
VERSION     DACGDM010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.237"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            96..506
                     /locus_tag="IXR05_002970"
     CDS             96..506
                     /locus_tag="IXR05_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4261390.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            520..876
                     /locus_tag="IXR05_002971"
     CDS             520..876
                     /locus_tag="IXR05_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAQ4261391.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          414 a          165 c          220 g          381 t
ORIGIN      
        1 ttattttgat ttttttttat atattattag ctaataattg gtattttaaa agaaattact
       61 gtagaattgg attataatta aaaatgagtg agaaaatgat aaaagtatat acttcgccta
      121 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      181 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagatc ttggcagcga
      241 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      301 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat
      361 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      421 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      481 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      541 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      601 tatcaatttg ttgacttaga agaacgcgat ctaagtacag aagaagcaga agaattatgc
      661 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      721 attgcgattg acctttcctg tgtaggaaaa aaacaactga tttttttatg cacacaacat
      781 accaatctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      841 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      901 ctgagcattt catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      961 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
     1021 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1081 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
     1141 ttgttgacat gttagaaatg acatgataag ataactgagt
//
LOCUS       DACGDM010000227         1176 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.238, whole genome shotgun sequence.
ACCESSION   DACGDM010000227 DACGDM010000000
VERSION     DACGDM010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.238"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..395
                     /locus_tag="IXR05_002972"
     CDS             <1..395
                     /locus_tag="IXR05_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261392.1"
                     /translation="QLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSFSVTAV
                     VSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLVEEAGE
                     HYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            409..810
                     /locus_tag="IXR05_002973"
     CDS             409..810
                     /locus_tag="IXR05_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261393.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            812..>1176
                     /locus_tag="IXR05_002974"
     CDS             812..>1176
                     /locus_tag="IXR05_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261394.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKL"
BASE COUNT          449 a          150 c          212 g          365 t
ORIGIN      
        1 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
       61 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      121 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      181 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      241 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      301 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      361 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      421 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      481 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      541 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      601 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      661 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
      721 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
      781 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
      841 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
      901 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
      961 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1021 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1081 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1141 gatgaatcga gaagcagaaa aaataataaa caaact
//
LOCUS       DACGDM010000228         1143 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.239, whole genome shotgun sequence.
ACCESSION   DACGDM010000228 DACGDM010000000
VERSION     DACGDM010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.239"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(18..923)
                     /gene="xerC"
                     /locus_tag="IXR05_002975"
     CDS             complement(18..923)
                     /gene="xerC"
                     /locus_tag="IXR05_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAQ4261395.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
BASE COUNT          338 a          232 c          194 g          379 t
ORIGIN      
        1 tgttcttttc cttattttta cgctcttgga tggaaagaac gatagttttt ttgtaaactt
       61 tcttttgtta catgggcata gatctgggta gtcgataaat tggcatgtcc tagcaattct
      121 tggactgtcc gcaaatctgc cccattattt aataaatgag tagcaaatgt atggcgcagc
      181 atgtgaggat ggatatcact atccaaactg ctttttttga tcatttgatt caagacatat
      241 tcaattccag taggcgtgat tggttttcca tgatgattca caaaaacgat atcatgctct
      301 tcgtgatatt ttgtcatcaa tacctggcgg ccttccctga aatattcttg cagagcatct
      361 tgagcaaaag aacctagagg agcatatctc tctttgttcc ctttaccatg gatcaacatg
      421 acctctgaat caaaatcaat gtctgatacc gacaaactgc tacactcact taaacggatg
      481 cctgacccgt aaaggacttc cagtaaagcg cggttcctca aatccaaagg actatctcct
      541 gctacgctgt caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg cagtctcaaa
      601 tttttctttt tgagatgaac gtaagaaaat ggattttctt ttatcacttc ttctttgaga
      661 agatactgat aaaacgaacg taggctggct atcttgcgac tgatagaatt tctgctatag
      721 ctaggacgat gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata ttccgccttc
      781 agcagatcag cgtctccaga ttcctccaaa aaatgtttga aatggagaat gtcttcttca
      841 tatgcttctt tcgttttttc tgaatatcct ctttcgacaa tcaaataacg caaaaatttt
      901 tgttcccacg tggcttctgt cattttctca ccttcctttt gtcccagaga ataatttagc
      961 acagcgttta taaaaagaca aataaattgt cagaatttaa ccaatatttc taagtttgtt
     1021 cacaattggc gcaattcctc acattttgtt tgagaaattc ttaagaaaaa cgcaagaaaa
     1081 agggctctat aatttatggg actgatgaat cagaattgat tcttcagccc cattttcatt
     1141 tta
//
LOCUS       DACGDM010000229         1131 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.240, whole genome shotgun sequence.
ACCESSION   DACGDM010000229 DACGDM010000000
VERSION     DACGDM010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.240"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..611)
                     /locus_tag="IXR05_002976"
     CDS             complement(<1..611)
                     /locus_tag="IXR05_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /protein_id="HAQ4261396.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKIT"
     gene            complement(604..>1131)
                     /locus_tag="IXR05_002977"
     CDS             complement(604..>1131)
                     /locus_tag="IXR05_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAQ4261397.1"
                     /translation="PRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHGSQW
                     WALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLP
                     LELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDKLL
                     NRIDKEILKVGNIDE"
BASE COUNT          417 a          174 c          134 g          406 t
ORIGIN      
        1 tttgttattt ttgaaattaa tacactaatt aaacttaaaa taatagaagt atatccaaac
       61 atagctccaa catttggact tgtatagaca ccaaataacc gatgttcaat aaaaccttgt
      121 cttgcaagta atcctggcgt tcctgttggg acatgataag aaatcaaaaa aataaattga
      181 tagatagata ttagcgcagc taaaaaaatt atgataatga aaacattatt aaaatacacc
      241 atttttttct ttttttcctc ttcactttgt gaaaagtctg caggaaaaat tactatcaaa
      301 gtaatcagca aatatccaaa attataaata gatggaatta aaaaattttc tctgttaatg
      361 attatagtta agataaaact aatcattgct ccaatcagta gccaagaaaa acgcatttta
      421 aaaaaatttt tctttataaa aacctcatac aaaactataa ttccacccca agcaaaagct
      481 attttcatcg ggatattagt tacattaaaa gtactaggca taaaataaag cagacaaatg
      541 attaaattta ttactcgaaa cgcatctcga cttaataaac tcttctctaa aacaggtact
      601 attctattca tctatatttc caactttcaa aatttcttta tcaattctat ttaatagttt
      661 atcagagtaa tccgatttaa cttttcttac aaataatttt tcactttctt ttatttgatc
      721 tatatccctt tcatcaaacc atttgttcat ggaaggatca ataatatgaa tatttgctaa
      781 tttcgaagtt tgtaaagtag tttcttcaat atttttcaat tcaagtggta aatctggtcc
      841 tccaataaca tttttatttt tgaacgagga attaaaaaaa agtgtatgaa aaaatttttc
      901 atctggggca aacataccta ttttaaaatt caggtagtct tgttgatttt gttcatacat
      961 ttgtattaat tctgttaggc attctttcga caaagcccac cattgagaac catgatacaa
     1021 atcaaattta tggtgtctaa tttttggggg aagtttaatc atcctcagac aacgattaat
     1081 tatagctcta aaaattttaa atgcagttgt gttattccta ttaattctag g
//
LOCUS       DACGDM010000230         1114 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.241, whole genome shotgun sequence.
ACCESSION   DACGDM010000230 DACGDM010000000
VERSION     DACGDM010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.241"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..897)
                     /gene="vanY"
                     /locus_tag="IXR05_002978"
     CDS             complement(<1..897)
                     /gene="vanY"
                     /locus_tag="IXR05_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAQ4261398.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHT"
BASE COUNT          328 a          228 c          159 g          399 t
ORIGIN      
        1 agtatgtgtt gatccgggaa acactgtcac aattacaccg tctatattgt ttcctgatat
       61 ctcataacga agattagtcg gcacatgaat ggtggtattt ttagtaacag gataataaaa
      121 gatctcatat ttttccccat ttacactaac agaaatggtt ttttcttctt ttaggtaatc
      181 catatattcc tcgagaacga aattcttttc tttcataatc gcactatgtg gtaaaccaac
      241 atagcgaata tgccatggtt catattgaat tcctgttaac tctgttttgt cctctggata
      301 acgtaaaatg aacccgtatt tccaagcatt ttcttctatc cactttcctt caggggctcg
      361 ttccattttc gtcaagcttg atcctacatc tagtgataaa cctgaattat gctcactata
      421 acctgctggt aaggcatact cagcccccat ttcttggtaa agcacacttt gctcatcaaa
      481 gtctcgatag ccactattaa taataaaatg actaacgcca ccctttacag catcattgac
      541 catctctgaa aatttttgtg ctatttcttt tgacatataa atattactat caagcaaccc
      601 gtatccattt attaattcgt catgtttaga taaattcacg atatctgact tcacactttc
      661 ttggcgaaca ggatatttac tattgattaa tagcagattt ccttgataaa cctgttcttc
      721 tgtaattgtt ttctcttggg tattttcaga agtcccacta ttttctaaat gttctttggg
      781 attttgatca taattttgaa attcgacttt ttcctgagaa aacagtgctt cattaacgta
      841 gtcataacct aagtatatta agaataacaa taacaataaa aaaaacaact tcttcatttt
      901 cagtctcctc cttaactata tagttggaag tatgaaatat ttctagaatc ttccccttaa
      961 acggcacaat ctcgtttgag attgtgccgt tttgccccgt aaattacagt caattatttc
     1021 gccctactgg atttactatt atcaccaatg tagatgaatt ttcataagtg atacccatgc
     1081 tgaatttaac gaggctgaac tgcctgttga caat
//
LOCUS       DACGDM010000231         1074 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.242, whole genome shotgun sequence.
ACCESSION   DACGDM010000231 DACGDM010000000
VERSION     DACGDM010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.242"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..276)
                     /locus_tag="IXR05_002979"
     CDS             complement(<1..276)
                     /locus_tag="IXR05_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261399.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV"
     gene            838..>1074
                     /locus_tag="IXR05_002980"
     rRNA            838..>1074
                     /locus_tag="IXR05_002980"
                     /product="16S ribosomal RNA"
BASE COUNT          350 a          194 c          206 g          324 t
ORIGIN      
        1 gacgtcaggc gtccaaccaa gagtgacttt ctctttaatg taatctactt catgagcagg
       61 taattgaatg acttttctac cacatttttt cttattttct ttatactggt gccaataatc
      121 aagagcagtc ttgccttgct tgaacttatt gactacatta taaatagttt gtatagcacg
      181 tcccattcgg ttagcgattt caaccggctt attatgttga agataatatg attctatcat
      241 tgtcagttcg tctatggtaa gatgtttgta ggtcatttat ggttacactc ctttgttttc
      301 tttcgtcgga aatacaattt gagtgtacca taaatgcctt tttatttttc taacttaatt
      361 ttacaattcg cgatatatta aacaacgttg tcgcgcttca ttgaaacatt ttatgaaaat
      421 tccaaaaaag agttgacaca tgtttttaga cgtgataaga taactaagtc gttaaaaaga
      481 accacttgcg aagcttgatt ctatcgaaaa aaagcttcaa aaaagttctt gacaaataac
      541 aaacgataag ttatgataaa tgagttgctg aaagatttcg aaaaacgaaa tcgaaaaaaa
      601 cttttaaaaa agagttgaca atcgcttgtc tctctgatat gatataaaag ttgctacggc
      661 agccaaaaac gaatcgggaa acactcccga tgaagtagac ctttgaaaac tgaacaaagt
      721 aagacaaacc aaatgtgtag ggcgtcttga ttcaattcaa gacaataaac atttttaaca
      781 agcaagcaat atgctagcaa acaaattgag cttaacaatc gcaagattgt tcgaactttt
      841 tatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagtc
      901 gaacgcttct ttttccaccg gagcttgctc caccggaaaa agaggagtgg cgaacgggtg
      961 agtaacacgt gggtaacctg cccatcagaa ggggataaca cttggaaaca ggtgctaata
     1021 ccgtataaca atcgaaaccg catggttttg atttgaaagg cgctttcggg tgtc
//
LOCUS       DACGDM010000232         1059 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.243, whole genome shotgun sequence.
ACCESSION   DACGDM010000232 DACGDM010000000
VERSION     DACGDM010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.243"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(37..993)
                     /locus_tag="IXR05_002981"
     CDS             complement(37..993)
                     /locus_tag="IXR05_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261400.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DACGDM010000233         1051 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.245, whole genome shotgun sequence.
ACCESSION   DACGDM010000233 DACGDM010000000
VERSION     DACGDM010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.245"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            6..980
                     /locus_tag="IXR05_002982"
     CDS             6..980
                     /locus_tag="IXR05_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAQ4261401.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          377 a          132 c          182 g          360 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt t
//
LOCUS       DACGDM010000234         1037 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.246, whole genome shotgun sequence.
ACCESSION   DACGDM010000234 DACGDM010000000
VERSION     DACGDM010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.246"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            404..1037
                     /locus_tag="IXR05_002983"
                     /pseudo
     CDS             404..1037
                     /locus_tag="IXR05_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          358 a          183 c          186 g          310 t
ORIGIN      
        1 attaataaaa tattttttat attacaaaag tagtgtttca aagttagtag agaaaatgta
       61 gttatatatt taaattttta ccagaaagaa atgaacacct tcaattatct aaatctcgaa
      121 aatggttaga tgtaatcatc aggaaaaaca atcttaaacg aattactatt catggtctta
      181 gacacacaca tgctagcttg cttttagcaa gctagtgcaa atattaaaga tgtgcaagag
      241 cgtttaggcc actcttctat tcaaatcatt atggatctat atattcatat tacagacaaa
      301 agaaaagaag aaaccgtagc gcaattcgca aaatataggc tctataattt atgggactga
      361 tgaatcaaaa ttgattcttc agtcccattg ttattttagg tatatgattc gtacattgaa
      421 agagttgaaa aactatcttc cgaagccgtc aaaaaggacc ctgccaaaag tattgatggt
      481 ggatgaattt cgttcgcacg cttcaattgt ggataaaatg agctttattt gtgcggatgg
      541 cgagactgga aaactcattg atattttgcc tacacgaaaa ttgtctcgat taacacacta
      601 ttttagtcgc tgtgcaaatc ctgaagcggt ggaatattta gtgacagata tgaacgccgc
      661 ctacttccaa ctgacaaaac gtgtcttacc aaatgcgaaa gtcgtcattg attgttttca
      721 tatcatcaaa catttgaatc aggcgttcaa tgattttcgt gtacaagaaa tgaaaagatt
      781 acaccagtta gggcaacgac gggaagccga gaaagtgaaa aagaactggc gctttcttct
      841 aaaaaaccgt caaaaaatca atcactatga ttacaaaaca tggcgcagtt ttcgtgcacc
      901 taaatacccg ctactcactg aagcaatgat gattgatcga ttgctggcat tttcaacgcc
      961 tttaaaggac gcctatactt ttttccatga gctgaccgaa gcctttagag acaaggaatc
     1021 agacttattt tttacct
//
LOCUS       DACGDM010000235          999 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.247, whole genome shotgun sequence.
ACCESSION   DACGDM010000235 DACGDM010000000
VERSION     DACGDM010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.247"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            170..>999
                     /locus_tag="IXR05_002984"
     CDS             170..>999
                     /locus_tag="IXR05_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4261402.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          351 a          145 c          170 g          333 t
ORIGIN      
        1 aatgaggtca ttaaatctta ttatctttag tgatataacg aaatatctac acagacaaaa
       61 tgatagcgta aaatattttg tgtaaataga tatttagggt agaaaaaaag aaagtccatt
      121 ctgtaaaatt aaagttacca caaccgaaat tttataggag gactttctca tgcccaattt
      181 tactacagaa attatggaaa cactaatcaa taaaggtgat ttagatgaat tatttcgatg
      241 tcatttagaa ttagctgtta attcattatt gcaggctgaa ttaacagctt ttcttgatta
      301 tgaaaaatat gatcgtgctg ggttcaattc aggtaattcc cgtaatggga attattcacg
      361 ttcattcaga acagagtatg gagaattaaa tttggtaatt cctagagata gaaatggtaa
      421 gttttctcaa caaactttac ctgcttataa aagaaccaat gactctttag aaaccactat
      481 tattcagcta tttcaaaaag gaattactat gtctgaaatc tctgaattga ttgaaaaaat
      541 gtacgggcat cactatacgc cacaaaccat ttcaaatatg actaaaatag tttctgaaga
      601 tattattgcc tttaaagaaa ggtccttaga atccagatac tctgtcattt ttatggatgc
      661 tactcacatt cctttaaaaa gacaaactgt ttcaaaagaa gcagtttata ttgtaattgg
      721 cattcgatta gatggaacca aagaggttct tgggtttagt cttgctccaa ctgaatctgc
      781 ttatgtttgg aaagagattc ttcaagacct aaaagaccgt ggtttaaaag aggttttatt
      841 agtcgtaact gatggtttaa gtggcattaa cgatagtatt catagtgttt atccaaatgc
      901 tcaatttcaa caatgttgtg tccatatatc tagaaatatc gctcataagg ttcgtgttag
      961 tgatcgacaa gaaatctgta gcgatttcaa attagttta
//
LOCUS       DACGDM010000236          995 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.248, whole genome shotgun sequence.
ACCESSION   DACGDM010000236 DACGDM010000000
VERSION     DACGDM010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.248"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(26..913)
                     /locus_tag="IXR05_002985"
     CDS             complement(26..913)
                     /locus_tag="IXR05_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4261403.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT          288 a          207 c          179 g          321 t
ORIGIN      
        1 taatttcttt gcctttttat ctaaatcaaa cgtttagttc ttgaccaact aataaagaat
       61 aactggacat agacatgcca tttttcgcca ttagatcatc aacagacatg ccaaattttt
      121 gtgcaatatc ccatagcgta tcacctgaca cgactgtata tgtctgacca ttatttgtat
      181 ttacatctgt tgttgaagat gatgacgttg aagtcgtcgt agtagtcgtt gttgttgtac
      241 ttgtggttgt tgtagccgaa cctgttgatg gcgtatcaaa acgggttaaa ttataagtat
      301 taatcaatga gttcaatttg gccccataat ttggatcggt agcataacga cctgtcaagt
      361 acgctgttgc atcataaaaa cttgttgtat tgcttttcca cacgccagca taatgataat
      421 cgcccgtgga aaaactggtt gaacgaagaa cattcgcatg gtcttggaag gattcccaat
      481 aagaagaata ttttcggaat ggctcattca tcgttaccca ttgtccgttt acatattctt
      541 tggttgccat ataaacgacc tgtccgttat agcttccttt cacaccgaat agattataat
      601 ttggcgcact agctaatccg gaagtgccat atgcactttc caacaacgct tgagcgatca
      661 tgactgaagc atacaagtca ttacttgcag caacttctga cgcagaccag ccgatttgat
      721 cgataaacgc ttgaggatca gcgactgttt gagatccttg ttcatctgca tgaacatgtt
      781 gcggtaccgc tgtaaccatc atcggcccaa ctaaaagact cgttccaatt aaaggagcaa
      841 tcgctttttt attgatcacc atttttcttt taggtctatg gtgccgggca ctgcgggtct
      901 tcagctcttg cattcaaatt cctcctcaaa ataaaaaaac ttaataaaaa gttctcttct
      961 taaaacaaac ttaattaatt aaattatact tttaa
//
LOCUS       DACGDM010000237          994 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.249, whole genome shotgun sequence.
ACCESSION   DACGDM010000237 DACGDM010000000
VERSION     DACGDM010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.249"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..>994)
                     /locus_tag="IXR05_002986"
     rRNA            complement(<1..>994)
                     /locus_tag="IXR05_002986"
                     /product="16S ribosomal RNA"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DACGDM010000238          992 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.250, whole genome shotgun sequence.
ACCESSION   DACGDM010000238 DACGDM010000000
VERSION     DACGDM010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.250"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..748)
                     /locus_tag="IXR05_002987"
     CDS             complement(<1..748)
                     /locus_tag="IXR05_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4261404.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEK"
     gene            complement(824..970)
                     /locus_tag="IXR05_002988"
     CDS             complement(824..970)
                     /locus_tag="IXR05_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAQ4261405.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
BASE COUNT          377 a          158 c          110 g          347 t
ORIGIN      
        1 ctttttccaa tatcgaatca tggttttgat tagcgatttc ttttaaactc agcaataaat
       61 ttttatagtc atgtctaaat ctggcaaatt tttcttgatc tttttccagt gaatcagtat
      121 atttttttag ataaaccaat tcttttcttt tcaattgctg ttcatattgt tctcgttgcc
      181 taatagttat tctaataaat aaaaatagaa caacaaacat ttgaatgatt aaaaatatta
      241 agacaccaaa cacaaaatga tcaaatactt gatattgatg agcaacataa gaaacaaata
      301 aaccaattgt aagtaaataa atcatgaata tagcagtaag tttagaactg gactgttcaa
      361 caatcctatt tatagctaat tttctatata accaaataaa catcagcaaa aacaaagaat
      421 caagcattat ctggaatact acataaccat acccttttat cccttcaaat gaaaacatat
      481 acgtcataac catggaagta ataatagatc tgaaatcatc aataagcata cataatagta
      541 atttatttaa aagcactata ttagttttct tcttttcctt taatataaaa taacttccga
      601 ttataggtat agctgcggaa acatcagtaa ataattcaac aaaaaaagtg agtggtatca
      661 ataaacatac aaaaagatat tttcttttgt taagatcagt attagtcata taaaataaga
      721 gaaaaaagaa aaagtttccc acgaacattc ttaatagata agcttttgta tcgatagtaa
      781 tcaagagatc ccctcctgat tttaggatat cataaaaaaa attttagtta cactttttaa
      841 ataatgaaaa aacacattcc actaaatttg atgccggttt tccttgaggt tttgttccag
      901 cacctccttt aattttttta agctcttgat ctgaacattg tttagcattt agtctatttt
      961 tttcttccat tacgattccc cctacaaact at
//
LOCUS       DACGDM010000239          974 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.251, whole genome shotgun sequence.
ACCESSION   DACGDM010000239 DACGDM010000000
VERSION     DACGDM010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.251"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            82..>974
                     /locus_tag="IXR05_002989"
     CDS             82..>974
                     /locus_tag="IXR05_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAQ4261406.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINH"
BASE COUNT          331 a          182 c          191 g          270 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc atta
//
LOCUS       DACGDM010000240          967 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.252, whole genome shotgun sequence.
ACCESSION   DACGDM010000240 DACGDM010000000
VERSION     DACGDM010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.252"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..843
                     /locus_tag="IXR05_002990"
     CDS             <1..843
                     /locus_tag="IXR05_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAQ4261407.1"
                     /translation="KESFSIVHNQVYFGGGINLWLAKKNGIRQRIAHSHATEDGKSQN
                     IVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQNHPFEIVHNGIDLELYSKNSEAKV
                     NKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFLEILKMNSDSYLILVGEGSLRNKL
                     KAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMPSLYEGLPMVGLEAQAAKLKLVLA
                     DTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYANKITQELKSYDVSYTTEQMESIY
                     SRDH"
BASE COUNT          370 a          110 c          185 g          302 t
ORIGIN      
        1 aaagaatctt tttctatagt tcacaatcag gtttattttg gcgggggaat taatttatgg
       61 ttagccaaaa agaatggaat cagacagaga attgctcata gccatgcaac tgaagatgga
      121 aaatctcaaa atattgtaat gaatgtattg cgtaaatttt taaccaaatt gttgttacaa
      181 aatgcaacag actaccttgc cgttagtcaa gaagctggtg aaagtctgtt tcaaaaccat
      241 ccctttgaga tagttcataa tggtattgat ttagagcttt atagtaaaaa ttcagaagct
      301 aaggttaata agagaaaaga attggatatc tcaatgagta cttttgttgt gggaaacatt
      361 ggacgattag agaaacaaaa aaatcaatct tatttgttag agattttttt agaaatacta
      421 aaaatgaatt ctgattctta cttgatttta gtaggtgaag ggtcacttag aaataaactg
      481 aaagccaaag cagtagaatt ggatatagag aaaagagtaa aatttttagg agaaagaaac
      541 gatattcccg agttattatc tgtgatggat gtttttgtaa tgccttctct ttatgaaggt
      601 ctgccaatgg ttggattaga agcacaagca gcaaaattaa aattagtctt agcagatact
      661 atttccaaag atacaaagtt aacaaataat gtggattttg tatcattaga tgaaacacca
      721 caagaatggg caaaaaaagt aataaaagag ccgtatgcta ataaaataac acaagaacta
      781 aagagttatg atgtttcgta cactactgaa caaatggaga gtatatatag tagagatcat
      841 taaaaatgtt caagatattt taggagtgat tatttttgaa aatatgttat ttgatattgg
      901 catacaatga tattggcaac ttaaagagat tggtcaatcg attgaacgaa aatgcagttt
      961 ttattat
//
LOCUS       DACGDM010000241          966 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.253, whole genome shotgun sequence.
ACCESSION   DACGDM010000241 DACGDM010000000
VERSION     DACGDM010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.253"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..>966
                     /locus_tag="IXR05_002991"
     CDS             <1..>966
                     /locus_tag="IXR05_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261408.1"
                     /translation="FMLSYFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGS
                     NAEFENFIKLCSTLLYLILAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVS
                     YGLNGLISYIKSLITGETNTANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIV
                     SLILIFMGLKRIELLALSGAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDT
                     GILALLMSNLGITDDGARLSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLN
                     GGRIAASLHSDILTIYIEVGCIVFIIWMFWLFFVKPIRLTKKFGLK"
BASE COUNT          303 a           96 c          172 g          395 t
ORIGIN      
        1 tttatgttaa gctatttttc ttatcgtgag aaaacatata aaaaatacgt tatcaagaat
       61 aacttttggt tgactataat gccgtttgtg atattttcta tctatactct aataatatgg
      121 ggaattggtt caaatgcaga atttgaaaat tttataaagt tatgttccac gttgctttat
      181 ttaattcttg catatggtta cgcatgtaca gcattttact tatttaaggc agaaggaatt
      241 gattttattt tttggtcagg tgttatttca tatatgagtg gttcagtttt ttatttaatt
      301 gtatcttatg gtttaaatgg tttaatttct tatataaaaa gtcttataac aggtgaaaca
      361 aatactgcaa attttgctat ggaggtacat gatttaactt ttgcgatggg ggtttttttc
      421 ctttattacg tattttttga aaataaaaat acaaaaaaac ataagataaa aattatcgta
      481 tctttaattt taattttcat gggattgaag agaattgaac tgttagcttt aagtggtgca
      541 attctagtgt attatgtttt attaaagtgg ggaaaaaaga ttcaaatccg tgcattagtg
      601 tgtactattt gtgcaactgt tatttcgtta gtgtttattt acattataga tacaggaatt
      661 ttggcattgc ttatgtcaaa tttgggcatt acagatgacg gtgcgaggct ttcattttat
      721 ctatattcat ctaaatttta tgaacttggt ttaggatatg taggaacagg atggacatgg
      781 ttttcaaaat acttttttaa tctttattta tcgcacttta ggttaaatgg tggaagaatt
      841 gcagcaagcc tacacagtga tatattaact atttatatag aagttggatg tatagttttt
      901 attatatgga tgttttggtt attttttgtg aaaccgataa gactaactaa aaaatttgga
      961 ttgaaa
//
LOCUS       DACGDM010000242          959 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.254, whole genome shotgun sequence.
ACCESSION   DACGDM010000242 DACGDM010000000
VERSION     DACGDM010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.254"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(107..511)
                     /locus_tag="IXR05_002992"
                     /pseudo
     CDS             complement(107..511)
                     /locus_tag="IXR05_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(570..>959)
                     /locus_tag="IXR05_002993"
     CDS             complement(570..>959)
                     /locus_tag="IXR05_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4261409.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          287 a          170 c          159 g          343 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaata attttgtgta
      541 aataaattgt cctcctgcaa aataattagt tactcagtaa acattgaaac taatgtatcg
      601 gttacctgtt gaaaaccttt atggcttctg tttagaaatt tttgattgta tgtatcaaaa
      661 atgctgacta gaaagcgttc tagtgattct tcattttgaa actgctcttt tctacggctg
      721 tatcttttaa tttgcttatt gaaagactcg attagattgg ttgagtaaat ggttctacga
      781 atgctaggtg gaaaatcata aaaagttaat aagtcttggt tttctatgag tgactgcgtc
      841 actttaggat agtttttctt ccatttctca atcatgccgg ataagaaggt attcgcttct
      901 tcttttgagt tagcttgata aacagcctta aagtcatcac agatttcttt tcggtcttt
//
LOCUS       DACGDM010000243          931 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.255, whole genome shotgun sequence.
ACCESSION   DACGDM010000243 DACGDM010000000
VERSION     DACGDM010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.255"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..>931
                     /locus_tag="IXR05_002994"
     CDS             <1..>931
                     /locus_tag="IXR05_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4261410.1"
                     /translation="HCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFY
                     RPLNPFKQTLPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFS
                     RFSLATREAVQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETT
                     VRLKGNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAA
                     CPNLRQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNA
                     LHYSYSNGPLECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          286 a          190 c          180 g          275 t
ORIGIN      
        1 acactgtttc attagtcaaa aagttcgttg gtctgtcatt gctcgcttaa aagagaatac
       61 ttccatgacg gaaatcgctc gtcagaaaaa tatttccact tcttcggtct atcgtgtcat
      121 gaagcgattc taccgcccat tgaatccttt caaacagact ttgccaaagg tcttatgctt
      181 tgatgaattc aaatcggttc gaagtgttgc cagtgcaatg agttttatca tgatggacgg
      241 acaaagccat gcattattgg atattgtcga aaatcgacgc ttgccttatt tagaacgcta
      301 tttttctcgg ttttcattag cgactcgtga agccgttcaa ttgattgtta ttgatatgta
      361 tgcgccttat gtttcgttgg tgaaaaagct tttcccgaat gctcagttga tcatcgatcg
      421 tttccacatc gtccaacata ttggcagaac tttcttgaat catcgagtga aagaaaccac
      481 ggtacgactt aaaggaaatt cccactctca acgagggtta gggaaaaaat tgaagcgcta
      541 ttggaaactc ctacaaaaag aagaagcaaa gttaaactat gaaaaacggg tttggcgtgc
      601 cagttttaaa gattatttga ctgaaagtga gattgccgat cgactgttag ctgcttgtcc
      661 caacttacgc caaggctatc agttatacca agacattctt tatgcggtaa agaaaagaga
      721 tcagtcacta tttgaggatt gtttaactag agacattagc ggtctgccag aaacctatac
      781 aaccacttta cgaacgttta aaaagtttct gccacagatc caaaatgcgc ttcactacag
      841 ctattcaaac ggaccattgg aatgcttaaa caaccacatc aaagtattaa aacgcaatgc
      901 gtacggcttt cgcaactttt acaatttcaa a
//
LOCUS       DACGDM010000244          915 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.256, whole genome shotgun sequence.
ACCESSION   DACGDM010000244 DACGDM010000000
VERSION     DACGDM010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.256"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            2..>915
                     /locus_tag="IXR05_002995"
     rRNA            2..>915
                     /locus_tag="IXR05_002995"
                     /product="23S ribosomal RNA"
BASE COUNT          285 a          183 c          263 g          184 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaa
//
LOCUS       DACGDM010000245          904 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.257, whole genome shotgun sequence.
ACCESSION   DACGDM010000245 DACGDM010000000
VERSION     DACGDM010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.257"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..590
                     /locus_tag="IXR05_002996"
     CDS             <1..590
                     /locus_tag="IXR05_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4261411.1"
                     /translation="DNIEKINNNLTILDTALENKEQKISILNSQLSSNNQTLEQLRTN
                     IEVSKQKVASLENDKNQLVSEKTNLENQLSAKDSELQGKQNEINAKIDEINQKVAEIN
                     RLNSDWNNRLQNEKNKFNEEQSTINSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSK
                     NSSLNNYIEKLQKAKNDVEDTANKAQQIVNEHTIQ"
BASE COUNT          407 a          112 c          123 g          262 t
ORIGIN      
        1 aagataatat tgaaaagatc aacaacaatt taactatatt agacacagct ctagaaaata
       61 aagagcaaaa aattagtatt ttaaattcac aattgtcttc aaacaaccaa actcttgaac
      121 aactaagaac taatattgaa gtttccaaac aaaaagtggc atctttagaa aacgacaaga
      181 atcaattagt atcagagaaa actaatttag aaaatcaatt gtcagcaaaa gactctgaat
      241 tgcaaggaaa acaaaatgaa attaatgcga aaatagacga aattaaccaa aaagtagctg
      301 aaataaatcg attaaatagc gattggaata atcgtttaca aaatgaaaag aacaaattta
      361 atgaagaaca atctactatt aatagtttaa accagcaaat taatcaaatg ttgagtgaaa
      421 aaaataacat tcaaaatcaa ctgcaagcta ctcagcaaaa gctagaagaa gaaaagtcaa
      481 aaaatagtag tttgaataat tacattgaaa agcttcaaaa agctaaaaat gatgtagagg
      541 ataccgcaaa taaagcacaa caaattgtaa atgaacatac aatccaatag atatagtttt
      601 aatttaacaa atggtatgtt tggagataat gagatagaat ataaatgtca taatattata
      661 caatctaaac accgtttcct tttctatttt tgatgacatc agtatatagc tactcgaaag
      721 agtagtcttt ttattattct cgcttattat tgatatgaaa atttcgattt gacaaaaggt
      781 accgaataat tttgtaatat gaattattat caagaagtaa ttatgatgat aacatatgga
      841 aactagttag taataataac aggtgattaa acttttgaac gacttgtaat tctatatttt
      901 ttct
//
LOCUS       DACGDM010000246          893 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.258, whole genome shotgun sequence.
ACCESSION   DACGDM010000246 DACGDM010000000
VERSION     DACGDM010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.258"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            253..876
                     /locus_tag="IXR05_002997"
     CDS             253..876
                     /locus_tag="IXR05_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4261412.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          329 a          129 c          166 g          269 t
ORIGIN      
        1 aaactaatgt ccttattttt gtgttcacat ttctgttacc taagaaatac ttaaaggagg
       61 tgatgtagcc agcaacgact acaacttgaa cccgctatct acagtttatt tgttgtttct
      121 tttgggtata ctctaatggt acaaatccat atttgcttaa agcgttgatt tttcagcggt
      181 ttttctttat tgcaaagtgt accctaagac ctgtatacta atagtaaata gattggatag
      241 gaatgatggc aaatgtattt agcttattta agagtttctt ccgacgatca aagtttagct
      301 cggcaacata agctaattga aaattggtca gtcaaaaata atattgctga agacgattta
      361 aaaattttcg aggaaaaagt ctctggaaaa aatattgaaa acagaccaga gctgcaagag
      421 cttatttctt tcatacgtga acgagatacg attattattc ctagtcttga tcgattagca
      481 agaaatagta aagatacaaa agacttactt caattgtttc gtagtaaagg tgcttctatt
      541 gaaatattag acctaccgtc gtttaatggg gtaactgacc ctgcattaag agacttgcta
      601 acaaatttag tcatagaagt gtttagctat gttgctgaaa acgaacggaa aaaaatcaaa
      661 gagcgtcaaa aacaaggcat tgaaattgca aagaaaaatg gtcgttatac tggtaaaaag
      721 attcaatacc atgccaatgc aacaggaaaa aacaaattga tttacgatga aattgttgat
      781 ggtctgaaga aaaaagaaac tatttctaaa atagcaaaga acgcaggagt tacaagaaaa
      841 accgtttatc gagtaaaaag agatttagga atgtaatatg ttccagttag aaa
//
LOCUS       DACGDM010000247          890 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.259, whole genome shotgun sequence.
ACCESSION   DACGDM010000247 DACGDM010000000
VERSION     DACGDM010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.259"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..>890
                     /locus_tag="IXR05_002998"
     CDS             <1..>890
                     /locus_tag="IXR05_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAQ4261413.1"
                     /translation="WNQFLIQFAKGLEKVKAMGIAGIISTIVTIIANIFFLLILKWGL
                     IGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPLIATVVGWWIN
                     STADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKEYGDNETAKFY
                     GNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIANVLNCASGLLG
                     PILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSYVIYVVRKRAV
                     GKDIFIKHYHIVVESWGLLF"
BASE COUNT          279 a          112 c          175 g          324 t
ORIGIN      
        1 atggaatcaa tttctaatac aatttgctaa agggttagaa aaagttaaag ctatgggcat
       61 agcaggtatt atcagcacaa ttgtaacaat aattgccaat attttcttct tgcttattct
      121 gaaatgggga ttaattggtt ttttcattgc aaatatttta tcacagatta tttcagctac
      181 ttatctgtca gtattagtga gaatatggga atatatcgat tttgaggcta aagatcctca
      241 gctaaagaga gaaatgctaa attactcgat tccattaatt gcaactgttg ttggatggtg
      301 gattaatagt acagctgata ggtatgtggt ttcctttata gtaggtgtct cggcgaatgg
      361 cttattgtct gtggcatata aaatacctca aataattaat actttgcagg gaatatttat
      421 acaggcctgg caaatttctg caattaaaga atatggagat aatgagactg caaaatttta
      481 tggaaataca tttgttatga ttaatttgtt aatgtgcata acctgttcaa gtcttatcat
      541 attaactaga ccgttttcac atattcttta tgcgaaagac ttttatgaag cgtggaaata
      601 tgttccattt ttattaatag ctaatgtttt aaattgtgca tcaggtctgt taggacctat
      661 cttatcagca aaaaaagatt ctaaatccat gatgtggtct gcaatcatag gggcattagt
      721 taatgtgatt atgagtgtag tccttgttta taagataggg gttcaaggtg ccacaatagc
      781 cactgttata tgttcatatg taatatatgt tgttcgtaaa cgagctgtgg gaaaagatat
      841 ttttataaag cattatcata ttgttgtgga atcttgggga ttattgtttg
//
LOCUS       DACGDM010000248          886 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.260, whole genome shotgun sequence.
ACCESSION   DACGDM010000248 DACGDM010000000
VERSION     DACGDM010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.260"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            87..356
                     /locus_tag="IXR05_002999"
     CDS             87..356
                     /locus_tag="IXR05_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4261414.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            349..606
                     /locus_tag="IXR05_003000"
     CDS             349..606
                     /locus_tag="IXR05_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4261415.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
BASE COUNT          337 a           97 c          169 g          283 t
ORIGIN      
        1 tataagaagt tagaatatta atcatttgct taattgtaca atataatgta caattgtttt
       61 atagaaataa ataaggggtg aaaggaatgg aagcagtagc ttattcaaat ttccgccaaa
      121 atttacgtag ttatatgaaa caagttaatg aggatgctga aacacttatt gtaacaagta
      181 aagatgtaga agatacagtt gttgtattat caaaaagaga ttatgattct atgcaagaaa
      241 cgttgagaac actttctaat aattacgtca tggaaaaaat tcgtcgagga gatgaacaat
      301 tctccaaagg tgcatttaaa acacatgact taatcgaggt tgaatctgat gattaaggct
      361 tggtctgatg atgcttggga tgattatctt tattggcatg agcaaggaaa caaaagcaat
      421 ataaaaaaga ttaacaagtt aataaaagat atcgatcgtt ccccctttgc tggattagga
      481 aaacctgagc cattaaagca tgatttatct ggaaaatggt ccagaagaat tacagatgaa
      541 catagactga tatatagagt tgaaaatgaa acgatattta tttattctgc aaaagatcac
      601 tattaaccaa tcggaagtaa ggaaagggtc agaaacttaa aagtttttga tccttatttt
      661 atttacccta gtcatttaaa aagctaatat agcttagtgt tgattgttat taatgaatgt
      721 gtttgttacg cgtattacgg atataaggtt agtaaaatca tttctaaagt tgaggaaaag
      781 taaatataaa tggcttaaat ttcaacaatt tgaagttgaa tagatatgtt ataatactat
      841 tgtagtgtgg gatgttagtt actaaaggat gacgcttata tatatg
//
LOCUS       DACGDM010000249          811 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.261, whole genome shotgun sequence.
ACCESSION   DACGDM010000249 DACGDM010000000
VERSION     DACGDM010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.261"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..672
                     /gene="tnpB"
                     /locus_tag="IXR05_003001"
     CDS             <1..672
                     /gene="tnpB"
                     /locus_tag="IXR05_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAQ4261416.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          298 a          126 c          152 g          235 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgtcaggttt a
//
LOCUS       DACGDM010000250          777 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.263, whole genome shotgun sequence.
ACCESSION   DACGDM010000250 DACGDM010000000
VERSION     DACGDM010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.263"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(20..532)
                     /locus_tag="IXR05_003002"
     CDS             complement(20..532)
                     /locus_tag="IXR05_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261417.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKK
                     DIETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLE
                     SIFSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSI
                     ISQNMDKLRY"
     gene            complement(539..>777)
                     /locus_tag="IXR05_003003"
     CDS             complement(539..>777)
                     /locus_tag="IXR05_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261418.1"
                     /translation="DFNSSTEFKLALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRG
                     TYIKFLENYNDLKSTNNYQFGNLSYEMISKVLSL"
BASE COUNT          266 a          112 c           74 g          325 t
ORIGIN      
        1 tattttaaaa ctaacatcct taatatctta atttatccat attttgagaa ataatacttt
       61 tccattcaga aactaattta gtaaggaatc ttgcaatgtt ttgtctcatt aattcattat
      121 ttctattatc tataagatct gttagatatt tttcaaattc taaaaagcta tccgaatttt
      181 cttcgacgat taaatactta agagaattta tatcggaaaa gatagattca agtttactaa
      241 tctcattttc taaatctata ttttcacgtg tgattatctc atcacttttt cttaaaaagc
      301 taaaaattgc atcagttgct ttacactttt ccattaaaga agtatattct tcaatttttc
      361 ttctttcttt atggtcattt tttaaatcag tttcaatgtc ttttttcatt tgttctatac
      421 tgagtttgtt ctttttgttc ttttgagtaa atctaaaatt caaacacgaa aaaagtatgt
      481 tagcaataac acctataata gcaaataaat catttatact atttaatttc atttatcatc
      541 acaaacttag aactttactt atcatctcat aagacaagtt tccaaattga taattattgg
      601 tagattttaa atcattataa ttttcgagaa attttatata agtacctctc atcggtttat
      661 ggctattaaa agtgttaaaa tcactatctt caactatttc ttgaaaccta tttaattttt
      721 caataaaaaa ttgtgcataa agtgctaact taaattcggt agagctatta aagtcaa
//
LOCUS       DACGDM010000251          760 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.264, whole genome shotgun sequence.
ACCESSION   DACGDM010000251 DACGDM010000000
VERSION     DACGDM010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.264"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            7..>760
                     /locus_tag="IXR05_003004"
     CDS             7..>760
                     /locus_tag="IXR05_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4261419.1"
                     /translation="MEIFGFYDTAFHINRALSLESIFSSPINFETFRSYGMQVNNFYP
                     WLTLYPLFLLIKFTNLAIGYNLFLYIVTLITLFICHYVMYEITKKHVTSSFFAIIYTT
                     SSFRSVEIFLRGAMGELLAMSILPLILLGFIKLYDSKKESWVMLAISMTLLIYTHVLS
                     VAMTMVMIIIALIIQFYRKKKIEIFLIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLN
                     RPYVDILQKRAIYLGKEFLIGSIDSELLSFGIG"
BASE COUNT          239 a          107 c          115 g          299 t
ORIGIN      
        1 aaaaacatgg aaatatttgg cttttatgat acggcatttc acattaatcg tgcgttaagt
       61 ttagaatcta tttttagctc ccctattaat tttgaaacgt ttagatcata tggcatgcaa
      121 gtaaataatt tttacccatg gttaactcta tatcctttat ttttattgat caagtttact
      181 aatttagcaa taggctataa cctttttctt tatattgtta cgctcattac tctatttata
      241 tgtcattatg taatgtatga aattaccaaa aaacatgtta ctagctcctt tttcgctatt
      301 atatatacaa catcttcttt taggagtgta gaaatatttc ttcgaggggc aatgggggaa
      361 ttactcgcaa tgtcaatact tcctcttatt ttactcgggt ttataaagct ttacgactca
      421 aaaaaagaat cttgggttat gttggcgatt agcatgactt tattaattta cactcatgtt
      481 ctttctgtag ctatgactat ggtaatgatt ataattgctt taattattca attttatcgg
      541 aaaaagaaaa tagaaatctt cttaattatt aaattaataa aagctgctat agttacttta
      601 cttctttcac tagcgtttat aggtcctatg attgagcaga cattgtatca agatctgaat
      661 agaccttatg tggatatatt acaaaaaaga gcaatttatc tgggtaaaga gtttttgatt
      721 ggaagtatag attcagaatt actatcattt ggtattggct
//
LOCUS       DACGDM010000252          753 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.265, whole genome shotgun sequence.
ACCESSION   DACGDM010000252 DACGDM010000000
VERSION     DACGDM010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.265"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..704
                     /locus_tag="IXR05_003005"
     CDS             <1..704
                     /locus_tag="IXR05_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4261420.1"
                     /translation="YSVIFMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAP
                     TESAYIWKEVLQDLRKRGLEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIA
                     HKVRVRGRKEICEDFKLVYQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFY
                     NFPHAIRRTIYSTNLIEGFNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRI
                     HKGFKEIQDTLESMI"
BASE COUNT          254 a          121 c          145 g          233 t
ORIGIN      
        1 attattccgt tatatttatg gatgcgacgc atatccctgt gaagcgacag actgtttcga
       61 aggaagcagt gtatattacg attggtattc gtttggatgg aaccaaagaa gttcttgggt
      121 ttactattgc cccaactgag tctgcttata tttggaaaga agttcttcaa gatcttagaa
      181 aacgtgggtt agaagaagtt ttattagtag tgacagacgg attaagctgt attgaagaaa
      241 gtatccatag tgtgtatccg aatgcccaat ttcaacaatg ttgtgtgcat gtatctagaa
      301 atatcgctca taaagttcgt gttcgaggtc gaaaagaaat ttgtgaggat ttcaaattgg
      361 tttaccaagc gaattcaaaa gaagaggcat tggatcacat cgactttatg actaggaaat
      421 ggaaaaagca gtatccaaga gtcgtcaatt tactcttgaa tcctgcccta ttaacctttt
      481 ataatttccc tcacgccatc agacgaacaa tttattcgac gaacctgatt gaaggcttta
      541 ataagcagct aaaacgatat actcgaagaa aagaacaatt ccctaatgaa gaatctctag
      601 agagattctt catttctcaa tttaatcaat ataaccaaaa atttttaggt agaattcaca
      661 agggatttaa agaaattcag gatacattag agtcgatgat ttaactgtaa ttaacagaat
      721 ggattttcca tttacatata attcttgacg cta
//
LOCUS       DACGDM010000253          750 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.266, whole genome shotgun sequence.
ACCESSION   DACGDM010000253 DACGDM010000000
VERSION     DACGDM010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.266"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(91..>750)
                     /locus_tag="IXR05_003006"
     CDS             complement(91..>750)
                     /locus_tag="IXR05_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HAQ4261421.1"
                     /translation="RIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQ
                     PLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLT
                     DVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQY
                     QFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEA
                     A"
BASE COUNT          204 a          175 c          143 g          228 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggtttgg ttatcaaatt cctttccccg
      421 gtctgtatga aaaagcttga cgtctgttaa agaatacggt atccgtccaa aggcttcttt
      481 taccaatgag gcatctttct tctcaccaca ggaataacca ataatttctc gattaaacaa
      541 atcaagtatt aagcagatat aatgccactt tttccccacg cgaacataag taagatccgt
      601 aacgatggct tccaatggct gttcttgtgt aaaggtccga tctaatacat tcgctgtttt
      661 cgcttcatta caagctgttc gttgcccttt aaaatgagcg atcgtatagg tagatgtcaa
      721 tccgcggcgt ttcatgattc gaccgattcg
//
LOCUS       DACGDM010000254          741 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.267, whole genome shotgun sequence.
ACCESSION   DACGDM010000254 DACGDM010000000
VERSION     DACGDM010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.267"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            132..344
                     /locus_tag="IXR05_003007"
     CDS             132..344
                     /locus_tag="IXR05_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261422.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            506..>741
                     /locus_tag="IXR05_003008"
     CDS             506..>741
                     /locus_tag="IXR05_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261423.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVLDILNMYRDITFSKNKL"
BASE COUNT          271 a          105 c          126 g          239 t
ORIGIN      
        1 aaaacactat atattccgaa aagtgagtat ctccattcat aaaataatca acatatttaa
       61 aaaatctaat tagctttttt agtcaatcta aagttcttta ttctatgata taatgttact
      121 gtagaaagtt tgtggcggtt tggcaaatcc aattgaagga gcgtggtgcc tatgggctta
      181 ttagcttatc ggacgtactc tgtagaaagg aaatgcctga tttgttctca ttggatcaaa
      241 tcattgctat tatcggagca gcagcagtag ttattactgc cgtagcgaaa gctagcgatt
      301 cgattttagc ttggttaaag ttcaaaaaag aacaaaaaaa atagagccgt ctcaactttt
      361 ggcgaggtag acgagctcta aagctttatt tacatgccat ccgctttgaa cggactacac
      421 tgggcatgtg acagcatgcc ctttcattta tattatatct cattctttta tataatgaaa
      481 gtaaataaat catggaggat aaaatatgga taaatttaat agattaacat taataaatca
      541 gtttgaaatt ttaaaagctt taaatcctaa cgaagaaaaa tactatgctg aaaaaataga
      601 aatactaaca gaaggttacg aatatcacta tagtgaaata tttgaaaata tttctgatcc
      661 attgccagaa gaagattcgc ggtttgttct agacatatta aatatgtata gagatattac
      721 ttttagtaaa aataaattaa a
//
LOCUS       DACGDM010000255          736 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.268, whole genome shotgun sequence.
ACCESSION   DACGDM010000255 DACGDM010000000
VERSION     DACGDM010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.268"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..734
                     /locus_tag="IXR05_003009"
     CDS             <1..734
                     /locus_tag="IXR05_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAQ4261424.1"
                     /translation="DKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRK
                     LMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKI
                     YLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQ
                     YQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIR
                     WYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          318 a           94 c          122 g          202 t
ORIGIN      
        1 cagataaata tagcaagata aagcaagaaa ttacagcgat tgtaaaagaa tcaagaaact
       61 cttatggtta tcgtagagtc actttagcgt taaagatgaa aggatataca atcaatcata
      121 aaacagttag aaaattaatg tcccaaatgg gacttacctg tcaaatccga ataaagcgat
      181 ataaatctta taaaggaaca gtaggaaaaa ttgccaagaa tgtgttaaaa cgaaattttt
      241 cagtagatac acccaataaa aaatgggtga cagacgtcac tgaattcaag ataaaaggaa
      301 gaaaaatcta tctatctcct atacttgatt tatttaacgg agaaataatt agttatagta
      361 tatcaactag tccaacatat aaactgattg aagaaatgct tcaacaagca attaaaaaaa
      421 agggaactga gggttcactg attctacatt cagatcaagg atggcagtat cagatgccac
      481 aatatcaaaa aaaattaaaa gagaataaca ttattcaaag catgtctaga aaaggaaatt
      541 gcttagataa ttctgtaata gaaaattttt ttggtgtgct taaatcagag tttttttatc
      601 gagaaaaatt ccgatcaatt gagatatttc aaagtaaatt aaatgagtat attaggtggt
      661 ataataacaa aaggataaaa ctaaagttaa atggactatc tccagtagaa tatcggaaac
      721 agtccattaa atagtt
//
LOCUS       DACGDM010000256          712 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.269, whole genome shotgun sequence.
ACCESSION   DACGDM010000256 DACGDM010000000
VERSION     DACGDM010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.269"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..446)
                     /locus_tag="IXR05_003010"
     CDS             complement(<1..446)
                     /locus_tag="IXR05_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4261425.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT          216 a          123 c           95 g          278 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt
      601 tttatttggc ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc
      661 atttttatta ataaaatggt atattttata ttgttataaa aagagcccaa cc
//
LOCUS       DACGDM010000257          700 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.270, whole genome shotgun sequence.
ACCESSION   DACGDM010000257 DACGDM010000000
VERSION     DACGDM010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.270"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            261..542
                     /locus_tag="IXR05_003011"
                     /pseudo
     CDS             261..542
                     /locus_tag="IXR05_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            616..>700
                     /locus_tag="IXR05_003012"
     CDS             616..>700
                     /locus_tag="IXR05_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4261426.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSY"
BASE COUNT          254 a           90 c          119 g          237 t
ORIGIN      
        1 aaaagttttt gatcctttat tttcaagtct gatttggcag cttttcggca gctcatttat
       61 ttatggtcag aaatagatgc tgaaatttta atctattagc aaatagtcca gaacgtatga
      121 agaggagtcg gatatcattt gtcattaaca ccataaatat ttataaaatt cgtgttcacc
      181 tacaattaaa tttaatatat aatattcgtt gtaagggctt ataatttttt gttaatgaac
      241 aagataggaa gaaacattta atggacagtt ttcagagatt gtcactagta aatcaatttg
      301 agttattggc taaatttgag gaccaaaaca gatcttatta tgaaagaaaa atcgaaatat
      361 tgagagaagg ttacgagtat cattatgatg atgaaatttg gagtgatctt tctgagccat
      421 ttccgaaaga agattctcga tttgtattag atgtattgaa catgtatcga gatatcaatt
      481 ttagtaaatc aaagctaaac ttagatgaaa accaaattac taattcatac tatactcatt
      541 tcggttctgt tgcaaagttt tccaaaaaat ctattttagt gtaaaattga gaaaaaagac
      601 agagaggaca gagtaatgaa tcattttaaa ggcaaacaat tcaaaaaaga cgtcattatt
      661 gtcgctgttg gttactacct gcgttacaat ctaagctatc
//
LOCUS       DACGDM010000258          699 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.271, whole genome shotgun sequence.
ACCESSION   DACGDM010000258 DACGDM010000000
VERSION     DACGDM010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.271"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            480..>699
                     /locus_tag="IXR05_003013"
     CDS             480..>699
                     /locus_tag="IXR05_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261427.1"
                     /translation="MFIKYGADTVATMFTEEYQVDYYEVIDKCVHFVYEKVWNFMNFA
                     ISEEILRVQENRTGIFTRDRKLNLIAHYI"
BASE COUNT          278 a           79 c          124 g          218 t
ORIGIN      
        1 taatcctaat actgattttg tgtttaattg ttcatgaagt gaataaacaa ttgtgaatta
       61 aaaaaataaa aacctagtat aatcacttta ataaattgtt ggtagaaggt gatcaaaatg
      121 ggagtaaacg aaatgatgaa agtcagattg agtttttaaa tgataccttc ctcagaactt
      181 caaaacgaat tcaaagattc gttgacaaat cttgagcaag atcatttaaa aaaatatttt
      241 ctcttcattt gacgaaaaat gtttagaaat cttatataag tgaagataaa gtaattggtg
      301 taattaattg tagagaatag cctttgagca attgaagcga tacaattatt tagaaaatga
      361 acttcctcca gcatactaca tgattcctta cgggacgatg ttaaagaaga aagcaagaaa
      421 ttttagaagt attagtagat aaactaatgg gcttttctca atttaaggga gtagcccaaa
      481 tgtttatcaa atatggtgca gatacagtag caaccatgtt tacagaagaa tatcaagtag
      541 actattatga agtaatagat aaatgtgtac attttgttta tgaaaaagtg tggaatttta
      601 tgaattttgc gataagtgaa gaaatcttac gagtacaaga aaacagaaca ggaatattta
      661 ccagagacag aaagcttaat ttgattgcgc attatatac
//
LOCUS       DACGDM010000259          690 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.272, whole genome shotgun sequence.
ACCESSION   DACGDM010000259 DACGDM010000000
VERSION     DACGDM010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.272"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..461)
                     /locus_tag="IXR05_003014"
     CDS             complement(<1..461)
                     /locus_tag="IXR05_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4261428.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          219 a          126 c           98 g          247 t
ORIGIN      
        1 ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa ctcatcaaat
       61 aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt atattggtct
      121 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
      181 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
      241 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
      301 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
      361 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
      421 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
      481 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaga
      541 tatatatgta ctaccttata attaataagt aaaaggtagt acataaataa ggaaaagctg
      601 aaatatattg atttatagct ttcctcaaag taatgacgtt atttaattta tcgagaagca
      661 gagaatactc gcgactttag tcatgtagac
//
LOCUS       DACGDM010000260          685 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.273, whole genome shotgun sequence.
ACCESSION   DACGDM010000260 DACGDM010000000
VERSION     DACGDM010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.273"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..>685
                     /locus_tag="IXR05_003015"
     CDS             <1..>685
                     /locus_tag="IXR05_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4261429.1"
                     /translation="SALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVI
                     VGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREK
                     DYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWF
                     ESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDG
                     LLKSMDFNSV"
BASE COUNT          230 a          117 c          138 g          200 t
ORIGIN      
        1 tcagccttag aatattatca acagtataag aaaaacaaat caaactgtgg tagacgtccg
       61 cttgttttac ccgaggaaca atcagaatat attcaaagaa aggttgttca aggatggaca
      121 cccgatgtga ttgttggtcg tgcagcgttt cctattagtt gttctgctcg taccatttat
      181 cgtatgttca aaaaggggct atttgattct tctgacttac cgatgaaagg caagcgtaaa
      241 ccgaatggac atcaagaaag acgtggaaaa caaactttcc gccgctctat tcatgaacgt
      301 gaaaaggatt atagccaatt ctcaaatgag tttggtcacc ttgaaggtga cactatcgta
      361 ggtctgaaac ataaaagtgc tgtaattacc ttagttgaac gattatcaaa agttatcatc
      421 acattgaaac cgtgtggtag acaagcgatt gatattgaaa aaaaattaaa tcaatggttt
      481 gaatctgtac cgaaaaacct attcaaatcc atcacttttg attgtggaaa ggaattttca
      541 aattggaaac agatcagtaa tgtcaatgat attgccattt atttcgctga tccaggaacg
      601 ccgtctcaaa gaggcctaaa cgagaattct aacggattgt tacgtagaga tggtttattg
      661 aaatctatgg atttcaattc agtag
//
LOCUS       DACGDM010000261          635 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.274, whole genome shotgun sequence.
ACCESSION   DACGDM010000261 DACGDM010000000
VERSION     DACGDM010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.274"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..270)
                     /locus_tag="IXR05_003016"
     CDS             complement(<1..270)
                     /locus_tag="IXR05_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261430.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFR"
     gene            complement(276..>635)
                     /locus_tag="IXR05_003017"
     CDS             complement(276..>635)
                     /locus_tag="IXR05_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4261431.1"
                     /translation="RNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPP
                     RIDTKKLNMLETILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQC
                     ALMERAIAAKRKELDKK"
BASE COUNT          164 a          135 c          110 g          226 t
ORIGIN      
        1 acggaagtag aagaattcct tccagaagtc cgttggcatg cctgtatcga taaaaatatc
       61 gcctatcagc gcatagatga agtttcgttg ctgtacggtg aaacgtctag gatcaataaa
      121 acgaatttca atgactcgat caccatcgta gccgtcatac atcgtcttta gtcgatcaat
      181 gttcacttcc tcattgatgg ttgcgcttat gtcttttcct ttgaactttt tcagaaccgc
      241 tgaatatgaa tcgattaatg gtttaaacac tcatatcact tcttatctaa ttcttttctc
      301 ttagctgcta ttgctcgctc catcaaggca cattgctcat agcttaactg ttcaatagtt
      361 tcaacgttat cagctaagag ccctaattta tctgtctgct cattaacata ttcgattaag
      421 gttttggtca tatctttacc catctgctca ttgaaagctt ctagaatcgt ctctagcatg
      481 tttaatttct ttgtatcgat tctaggtggt gttggaatat cttccccttg aaatacatat
      541 aatcccagtc cgtgtagagc caatgctttc acaaagcatc gcttcaatga gttattgatt
      601 tgcattgcat ttggtttaac aactggttgg tttcg
//
LOCUS       DACGDM010000262          627 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.275, whole genome shotgun sequence.
ACCESSION   DACGDM010000262 DACGDM010000000
VERSION     DACGDM010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.275"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..624
                     /locus_tag="IXR05_003018"
     CDS             <1..624
                     /locus_tag="IXR05_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4261432.1"
                     /translation="MDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKIGTTASIFD
                     DIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIKMAIASSSP
                     MDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEECLVIEDSYN
                     GIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
BASE COUNT          244 a           68 c          115 g          200 t
ORIGIN      
        1 atggacggag ttttaattga tagcgagatt atgtatcaaa agtgggtatt taatttttta
       61 aaacaagaaa atttaagcta tcctttgtat tcttatcaaa aaaagattgg aactacagca
      121 agtatttttg atgatataga aaagtacaat gagggatgta acagtttaga attgaaggga
      181 aaatttacta aatattggaa atcgcaaaag attgattact tggatatttt tcctaatata
      241 ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa aaatggcaat tgcttcttcc
      301 agtccaatgg atactataaa tgaagttgtt accacttgta aaatagagtc atattttgat
      361 tgtttaatta gcggaagaga tttgccagaa agtaaaccta atcctactat attccttaaa
      421 gcttcagaac agctcagaat tccagttgaa gaatgtctgg tgatagaaga ttcttataat
      481 ggtataaaag ctggtaaaag agcaaatatg aaggttcttg caattaaaga taaacgtttt
      541 tctcaagatg taagtctagc agatgatgtt atttacgata ttaaatatct gcgacaagaa
      601 gtacaggtga aatttggaat ataaata
//
LOCUS       DACGDM010000263          606 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.276, whole genome shotgun sequence.
ACCESSION   DACGDM010000263 DACGDM010000000
VERSION     DACGDM010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.276"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            73..>606
                     /locus_tag="IXR05_003019"
     CDS             73..>606
                     /locus_tag="IXR05_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261433.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMIL"
BASE COUNT          219 a           88 c          124 g          175 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccgagaa ccttgggttt tcaagtgctt tttggttcat taatcttaac catagtgttt
      121 ttaaagtgga aaacaagcaa caaaaaaagt atgtggagcc ttgtaggaat agttcttatt
      181 atttttactg tgactgcagc aacagaagca aattattcgc ataaaattca gtcgtataaa
      241 ggtcgtttag ttatgaccaa aaaagatgtt acacgttata catcctcaag aactggaggc
      301 ctatatgact atgcaccatt agatgcattg aaatataaag atcatttaaa gaaacatgaa
      361 gtaaaagttg gtgatcggtg ggagaatgca tctcataaag catataattc caaaatagtc
      421 tatacagtag aagatgccga tgagcaaaat atcacattac ctgtattcaa ttattgggga
      481 acagttgtga aagtaaatgg gaaaaagagc actatagaaa atgacaatgg tttagtgtct
      541 attaaaggta cggggaaaag aactatagtt gaggtttcat ctacgtatcc aactacgatg
      601 attcta
//
LOCUS       DACGDM010000264          596 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.277, whole genome shotgun sequence.
ACCESSION   DACGDM010000264 DACGDM010000000
VERSION     DACGDM010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.277"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            134..532
                     /gene="spxA"
                     /locus_tag="IXR05_003020"
     CDS             134..532
                     /gene="spxA"
                     /locus_tag="IXR05_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAQ4261434.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          208 a           92 c          119 g          177 t
ORIGIN      
        1 cattttttta aaaaaattat gaaaaaaagg tagctattta aaagttgatt atgtataata
       61 gaaacagatg ggagattatt atgatcttct gttacaaaaa agtgattctt atcacgaaaa
      121 ggagtggtgc acgttgttaa cattatatac ttccccaagt tgtacttcct gcagaaaggc
      181 tcgtgcgtgg ttgcaagaac atcagattcc atttgttgaa cgtaatattt tttcagaacc
      241 attgaacagt tctgaattaa aagcgatttt acaaatgaca gaagacggaa cagaagaaat
      301 catctcgaca cgttccaaag tattccaaaa actgaacatg gatttagatg atctgccgtt
      361 acaagaatta ttggaacttg tgcaaaacaa tcctggattg cttcgccgtc caatcatgat
      421 tgatgataaa cgtctgcaag ttggttttaa tgaagatgaa attcgtcggt tcctaccgcg
      481 cgatgtacga caattagaat tacgtcaagc acaattgatg gctggattat agaaggataa
      541 tacgaaactt ggaaaagact ggctctttgt caaatgatgt tggtaaagag aaatct
//
LOCUS       DACGDM010000265          558 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.278, whole genome shotgun sequence.
ACCESSION   DACGDM010000265 DACGDM010000000
VERSION     DACGDM010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.278"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..>558
                     /locus_tag="IXR05_003021"
     CDS             <1..>558
                     /locus_tag="IXR05_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4261435.1"
                     /translation="SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHY
                     PKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIR
                     AYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDS
                     IEIIGSGYDSVAYLVNNEYIFKTKF"
BASE COUNT          229 a           49 c           99 g          181 t
ORIGIN      
        1 aatcattaaa aaaacattat acagagcctt gggaagatga agtttttaga gtaattattg
       61 aatataacaa tgttcctatt ggatatggac aaatatataa aatgtatgat gagttatata
      121 ctgattatca ttatccaaaa actgatgaga tagtctatgg tatggatcaa tttataggag
      181 agccaaatta ttggagtaaa ggaattggta caagatatat taaattgatt tttgaatttt
      241 tgaaaaaaga aagaaatgct aatgcagtta ttttagaccc tcataaaaat aatccaagag
      301 caataagggc ataccaaaaa tctggtttta gaattattga agatttgcca gaacatgaat
      361 tacacgaggg caaaaaagaa gattgttatt taatggaata tagatatgat gataatgcca
      421 caaatgttaa ggcaatgaaa tatttaattg agcattactt tgataatttc aaagtagata
      481 gtattgaaat aatcggtagt ggttatgata gtgtggcata tttagttaat aatgaataca
      541 tttttaaaac aaaattta
//
LOCUS       DACGDM010000266          537 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.279, whole genome shotgun sequence.
ACCESSION   DACGDM010000266 DACGDM010000000
VERSION     DACGDM010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.279"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
BASE COUNT          167 a          111 c           75 g          184 t
ORIGIN      
        1 aaccgggggc tttattcctg cagtccggct acgccttcct gcaatagaca aaactccaga
       61 tcgggtaatt cgcttgtggc gaaacccgac ctggagtttg tctctgtatt ttgaacccta
      121 aaaattaatc aaacagactg atattctcat aatcagcgcg aaataagcca ttaagtacag
      181 ttttcctacc tatttttgat aacccgctgg ttagttaata ttccttttcc gagagagata
      241 aatgattggt taaatctata tacatctcaa cctttaaaaa tgttttcgaa atacttcatc
      301 agtacatgtc atacaaatta ccagtgcatt ctcaaattct agttctttaa ttgatttcag
      361 ttgaggagca gttacttttg gcggaaattt ccatttttgt ccaaacctct tcccccgatg
      421 aaatttcttt gttgcaatta ttgcaatgaa aaatttttgt ttcaaaaata tacataatta
      481 cttcctccaa taaaaactat ctacctctca aattattttt ctctaataag aaaaaca
//
LOCUS       DACGDM010000267          526 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.280, whole genome shotgun sequence.
ACCESSION   DACGDM010000267 DACGDM010000000
VERSION     DACGDM010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.280"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(6..359)
                     /gene="tnpB"
                     /locus_tag="IXR05_003022"
     CDS             complement(6..359)
                     /gene="tnpB"
                     /locus_tag="IXR05_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAQ4261436.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          153 a          116 c           90 g          167 t
ORIGIN      
        1 ccagcttaaa aaactccttt ttttcctggc aaaatagctc gaggttgatc gatacttaat
       61 ccttctaaca accatcgaac ctgttggttc gttaaggttc gaacttcgtc tttcgtccga
      121 ggccatttta acttgccgtt ttctatccgc ttataacaga gaagaaaacc atcaccgtcc
      181 caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa ataaaaaaac ggcatcttcg
      241 taaagctcga gttgatactc ttgttgaata agactggcaa gaccatcaat tccttttcgc
      301 aaatctgttt ttccgcacac aatataaata tgtttggttt gaagtaaatc ataaagcatt
      361 ggacaacagt tctttcaaaa tagcttgaag aatataattg ttaataccgt tatagatcaa
      421 aacttcagaa ccattctctc ttttgatgcg catcgctaac ttggcagccg cgggtttacc
      481 tttttctggt gcactctttt cgtttcctaa ttggacagga acaatc
//
LOCUS       DACGDM010000268          517 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.281, whole genome shotgun sequence.
ACCESSION   DACGDM010000268 DACGDM010000000
VERSION     DACGDM010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.281"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..>517
                     /locus_tag="IXR05_003023"
     CDS             <1..>517
                     /locus_tag="IXR05_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261437.1"
                     /translation="IPLVTAGSRTALQLSDIFNPMIDIYKEKKYIFFTSVYDFEGGEP
                     VGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSSIPWEAIQLSGDFND
                     KIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAYDIERLLKQKTMKNI
                     LKNVKIAESLD"
BASE COUNT          199 a           63 c          100 g          155 t
ORIGIN      
        1 aaattccatt agttacagct gggtcaagaa ccgcattgca actttcggat atttttaacc
       61 ctatgataga tatttataaa gaaaaaaaat atatattttt tacgtctgtt tatgattttg
      121 agggcggaga acctgtcgga gaatatgaat tagtatgcaa aatagcagac ttagtaggaa
      181 aagataatct aattgttaag acgcatccta gagatgtaag aacaatttat aaagataatg
      241 gatttatcga ggataaaaat tcatcaatac cttgggaggc gattcaattg tcaggcgatt
      301 ttaacgataa aatatttatg acaattaatt caggaagtgt tatttcaggt agtacaatgt
      361 ctgcaaaacc tgtacgcacg tattatatgt ataaattgtg taacatagaa ggaaatccgt
      421 cttgcaaaaa gaatgcgtat gatattgagc gattgcttaa gcaaaaaacg atgaaaaaca
      481 ttttaaagaa tgtgaaaata gcagaaagct tagatga
//
LOCUS       DACGDM010000269          514 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.282, whole genome shotgun sequence.
ACCESSION   DACGDM010000269 DACGDM010000000
VERSION     DACGDM010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.282"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..132)
                     /locus_tag="IXR05_003024"
     CDS             complement(<1..132)
                     /locus_tag="IXR05_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4261438.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DACGDM010000270          509 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.283, whole genome shotgun sequence.
ACCESSION   DACGDM010000270 DACGDM010000000
VERSION     DACGDM010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.283"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
BASE COUNT          228 a           70 c           81 g          130 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactct
//
LOCUS       DACGDM010000271          497 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.284, whole genome shotgun sequence.
ACCESSION   DACGDM010000271 DACGDM010000000
VERSION     DACGDM010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.284"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..465)
                     /locus_tag="IXR05_003025"
     CDS             complement(<1..465)
                     /locus_tag="IXR05_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261439.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLKKLETLI"
BASE COUNT          142 a           97 c           63 g          195 t
ORIGIN      
        1 aatcaaggtt tctaactttt ttaaatatgc gttctctgct cttaaacgaa taacttcttc
       61 ttcaagagac tcatctttaa gttttttagg aatgtttagc ttggaattca tactaatttt
      121 tctgcccctt ttttggctct caagtgaaga agcaccgcct tcttcatatt gctctatcca
      181 tttacttaga gttctatttg aaccgatatt aaatttttta gcagtttctt ggatagaaag
      241 accatttgtt tccatatatt ctataacatc aagtttaaat tttgtagtgt agcttttgcc
      301 acctccaacc aagccttccc aaccatgata gttataaatc cttacccaat gtctaaccag
      361 tgtacgattt atttgatatt tatgtgcaag atatttgtag ccgccttcgt tatttaaata
      421 gtctgaaact acttttttct taaaaacaaa tgtatatttc cgcaaaaaaa gcaccccttt
      481 taattagatt tctagtc
//
LOCUS       DACGDM010000272          490 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.285, whole genome shotgun sequence.
ACCESSION   DACGDM010000272 DACGDM010000000
VERSION     DACGDM010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.285"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..200
                     /locus_tag="IXR05_003026"
     CDS             <1..200
                     /locus_tag="IXR05_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAQ4261440.1"
                     /translation="DECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFFENVVT
                     GKENWNDLYHANEVLKIAEEK"
     gene            201..>490
                     /locus_tag="IXR05_003027"
     CDS             201..>490
                     /locus_tag="IXR05_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAQ4261441.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFL"
BASE COUNT          190 a           56 c           97 g          147 t
ORIGIN      
        1 tagatgaatg tatcaatgtt gacttattaa ataataaaat aagttttgaa gaaaacattg
       61 ttaaagaaat gcctgaatct gctaatgata tgtatgagaa ggagttgaaa tatttctttg
      121 aaaacgtagt aacaggcaaa gaaaactgga atgatttata tcatgcaaac gaagtattga
      181 aaatagctga ggagaaataa atggaaattt tatttactat ttgtggtaga gctgggtcta
      241 aggggtttaa aaataaaaat ttgaaatatt tggcaggaaa gcccctagtc catttcgctt
      301 tagcaatgat agatatctat caacaaaaac atcctgaaca taattgcacg acttgtttga
      361 atacggacag taatgagtta gtagaattga cgactaagtt aaatccgtct gtgaaaattg
      421 tagaacgtaa acctgaatta gctacagata ctgtagggaa aattgaagtg atacgtgatt
      481 cattcttaca
//
LOCUS       DACGDM010000273          490 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.286, whole genome shotgun sequence.
ACCESSION   DACGDM010000273 DACGDM010000000
VERSION     DACGDM010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.286"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            124..327
                     /locus_tag="IXR05_003028"
     CDS             124..327
                     /locus_tag="IXR05_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAQ4261442.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
BASE COUNT          201 a           51 c           88 g          150 t
ORIGIN      
        1 tcaatcattg ttatataata aaatgttata taataaaatt actaatgata tttaatatta
       61 caagcaatct taagaaattc gaaaaggaaa aaatgattat gaaaaagaaa gaaaaagaaa
      121 gtattgaaac attgtgttat tctaggaata ttaggaactt gtctagctgg cattggtaca
      181 ggaatagacg ttgacgcagc tacttactat ggaaatggtc tttattgtaa caaagaaaaa
      241 tgttgggtaa attggggaca atcatggtca gaagggttaa aacgttgggg agataatctt
      301 tttggtagtt ttagtggagg acgataatga cttcaataaa cattgatcac acaaaaaaag
      361 tcatacatga attatacaat agtttaatga cacgacctaa tcagacgaaa gcattattag
      421 atattactga tgttttattt caggtatata aaaaaattga tacagcaaaa tatcctgaaa
      481 ttcttgtaaa
//
LOCUS       DACGDM010000274          485 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.287, whole genome shotgun sequence.
ACCESSION   DACGDM010000274 DACGDM010000000
VERSION     DACGDM010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.287"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(62..259)
                     /locus_tag="IXR05_003029"
     CDS             complement(62..259)
                     /locus_tag="IXR05_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4261443.1"
                     /translation="MNNGTVKWFNSDKGFGFITGEDGNDVFAHFSAIQGEGFKSLDEG
                     QAVTYDIEEGQRGPQAVNIVK"
BASE COUNT          158 a           89 c           68 g          170 t
ORIGIN      
        1 gaattttttc taccgacata aacaaaaaaa ccacctcata tgaggcggtt aacgttcaac
       61 attattttac gatatttact gcttgaggac cacgttgtcc ttcttcaata tcataagtaa
      121 ctgcttggcc ttcatctaaa gacttaaagc cttctccttg gattgctgag aaatgagcga
      181 atacgtcatt tccatcttca ccagtgatga aaccaaaacc tttatctgag ttaaaccatt
      241 ttactgtacc gttattcata tatatttcct cctgatacgt atataatacg tgttttattg
      301 caattaatat tacttggtaa aaggagtttt tatagtgtga atatatcgct cagattacgt
      361 ttcaaattag attacttatt tactataaca cggatgtaat gctaacacaa ggataatcac
      421 tcgatatacg gtttaaatat tattatttgt caaattaagc gagacaaaac tttccattta
      481 cgtaa
//
LOCUS       DACGDM010000275          471 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.288, whole genome shotgun sequence.
ACCESSION   DACGDM010000275 DACGDM010000000
VERSION     DACGDM010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.288"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            47..>471
                     /locus_tag="IXR05_003030"
     CDS             47..>471
                     /locus_tag="IXR05_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAQ4261444.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT          150 a           87 c           85 g          149 t
ORIGIN      
        1 ttatcttgaa tttgtatatt acttaacaaa agataatgga gtgtgaatga tggagaccat
       61 aacgtattcc cctttgaact tatttacgaa ttttcaagaa gctgcagcta acttttccga
      121 gaccccgatt atctttgatg agccactttc agctttccca gaattaggac ttgaaacaac
      181 ttacaaaaaa tgctgcgaaa gtgtgttgaa acgggcttat caattggctc atcttggagt
      241 gaaatccgga gacaaagtta ttatttataa gagttccgct tttgacacat accttctagc
      301 tgtttctgtg tcttaccttg gtgcagtgcc tgtcatgact tcttatcatc taccaacaac
      361 aacaatggaa gtatttatcg atcgtttaga agaccctttc attttatttg atgatgagac
      421 aaaaaagcga gtgagagaaa tttcaaatgg aacaaaatca aaacagattc c
//
LOCUS       DACGDM010000276          457 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.289, whole genome shotgun sequence.
ACCESSION   DACGDM010000276 DACGDM010000000
VERSION     DACGDM010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.289"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            50..>457
                     /locus_tag="IXR05_003031"
     CDS             50..>457
                     /locus_tag="IXR05_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4261445.1"
                     /translation="MKKTIFVLAIFICFGLLLVGYLLFNSNEMRTISTNDLLKKSELK
                     DKKKESLAFIMFTQEECEYCIAINPIIDSVNKETLNKIKKYDISVDFQSKQKCKIKFV
                     PTIVAYSKNKEVGRIDNELDNLYRKKQDGSIVID"
BASE COUNT          184 a           38 c           87 g          148 t
ORIGIN      
        1 gaaaacatga gcaatagaat tgtactagta ggataaggat ggatggaaaa tgaaaaaaac
       61 tatttttgtt ttagcgattt ttatatgttt tgggctactt ttggtaggct acttgttgtt
      121 taattctaat gaaatgagaa ctatttctac gaatgacttg ttaaaaaaaa gtgaattaaa
      181 ggataaaaaa aaagaatctc ttgcctttat aatgtttact caagaagagt gtgagtattg
      241 tatagcaata aatccaatca tagatagtgt aaataaggaa actttgaata agataaagaa
      301 atatgatata tctgtagatt ttcaatctaa acaaaagtgt aaaattaagt ttgttccgac
      361 tattgttgca tatagtaaga ataaagaagt ggggagaatt gacaatgaat tagataattt
      421 gtatcgaaaa aagcaagatg gttcaattgt aatagac
//
LOCUS       DACGDM010000277          442 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.290, whole genome shotgun sequence.
ACCESSION   DACGDM010000277 DACGDM010000000
VERSION     DACGDM010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.290"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
BASE COUNT          159 a           61 c           54 g          168 t
ORIGIN      
        1 tattacggaa aattatataa actaatttag tgttttgttt gtaattccta attttgctcc
       61 acttttagat aatttttagg tctatttaac tcatcagaca ttctatgctc atttttctcc
      121 aaatttgttt caactctttc gtacttaatt ttgcgtattt gaaaattctt cttttagagt
      181 acttttatta cgatactagt atgatatata tctatagcaa acagttaaaa tcttcctaaa
      241 ataagcgaat agcattccta aaacctataa aatttttaga tgaagcgaca agtggacaat
      301 taataaacta cttgaacatg aaattatgga tcacctttca aatttagaaa atggaattct
      361 tatacttatt gcgcaacatt tattgattgc aaaattatgt gacaaaaaaa actagtagaa
      421 gaaagaataa tggcttgata at
//
LOCUS       DACGDM010000278          437 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.291, whole genome shotgun sequence.
ACCESSION   DACGDM010000278 DACGDM010000000
VERSION     DACGDM010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.291"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(134..>437)
                     /locus_tag="IXR05_003032"
     CDS             complement(134..>437)
                     /locus_tag="IXR05_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4261446.1"
                     /translation="ITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGIL
                     RRNGLPKSMDFREVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT          142 a           70 c           67 g          158 t
ORIGIN      
        1 tctctttttt tgagttaaac cagaaataac tttttcaaaa taaaatttta acgccaatcc
       61 atgagtcaat tcaaaaaaag aaaaaagatt ctttgttttc tcagaagttc aattctttat
      121 tatttatgat ttgtcaaatt aagctagaat aaaatgcttc ttgtacatag ctcaaaaata
      181 tttcgattgg tgttctgtaa ttcaatgatt ttcttggaat atgattacgt tgattgctga
      241 cactggaaat aaatgtctga ttcacttctc taaaatccat tgatttcggc agtccattac
      301 gacgcagaat cccgttagaa ttctcgttta atgggcgttg agaaggtgtt ccagggtccg
      361 caaaatatat atcaatatca tgttggttac taatggcttt ccagttagaa aattcttttc
      421 cacagtcaaa cgtaata
//
LOCUS       DACGDM010000279          430 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.293, whole genome shotgun sequence.
ACCESSION   DACGDM010000279 DACGDM010000000
VERSION     DACGDM010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.293"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..178)
                     /locus_tag="IXR05_003033"
     CDS             complement(<1..178)
                     /locus_tag="IXR05_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4261447.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITK"
     gene            complement(197..352)
                     /locus_tag="IXR05_003034"
                     /pseudo
     CDS             complement(197..352)
                     /locus_tag="IXR05_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
BASE COUNT          143 a           76 c           47 g          164 t
ORIGIN      
        1 tttttgttat tgatattgaa gaattagaac tttcatataa agccttttct atttcattgc
       61 ttgatttcat tattgttaaa caagaataca agcaagaaag aactatagtt aatatgataa
      121 aaattattaa agttctattt ttctttcttg taatatatgc tatagcattt tttatcactt
      181 tcctaactac tcctctctat tttcttactc cataactaat tgcatccact ggacaagcat
      241 ttttacatcg tccacatctg atacactcca gatgattgca attctcaact gaatctttat
      301 tcatttggca aactttttta cattttccac aattaataca cttatcctta tcctgaatcg
      361 gctacactag actagacaga aaaaataagg tgtgtagaat aataaaaaac acactggagg
      421 atttttcatg
//
LOCUS       DACGDM010000280          415 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.294, whole genome shotgun sequence.
ACCESSION   DACGDM010000280 DACGDM010000000
VERSION     DACGDM010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.294"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..339)
                     /locus_tag="IXR05_003035"
     CDS             complement(<1..339)
                     /locus_tag="IXR05_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261448.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DACGDM010000281          409 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.295, whole genome shotgun sequence.
ACCESSION   DACGDM010000281 DACGDM010000000
VERSION     DACGDM010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.295"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..379
                     /locus_tag="IXR05_003036"
     CDS             <1..379
                     /locus_tag="IXR05_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAQ4261449.1"
                     /translation="IWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKL
                     KEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKT
                     RKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          139 a           79 c           81 g          110 t
ORIGIN      
        1 tatttggtta cgtaaaaaac gggacacaca agcagcctat gcttttctta agcggttagt
       61 gaagcagttt gatgaaccga aggttgtagt cacagataaa gccccctcta ttacaagtgc
      121 ctttaagaaa ctaaaagaat acggctttta tcaagggaca gaacatcgta ccattaaata
      181 cctgaataat ttgattgaac aagaccatcg tccagtaaag agacgcaata aattctatcg
      241 aagtttacgc actgcctcta ccacgattaa aggcatggaa gccattcgag gattatataa
      301 gaaaacccga aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt
      361 attgggaatc ccagcttaaa tcatagatac cgtaagggat tttattctt
//
LOCUS       DACGDM010000282          376 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.296, whole genome shotgun sequence.
ACCESSION   DACGDM010000282 DACGDM010000000
VERSION     DACGDM010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.296"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            17..214
                     /locus_tag="IXR05_003037"
     CDS             17..214
                     /locus_tag="IXR05_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAQ4261450.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            216..>376
                     /locus_tag="IXR05_003038"
     CDS             216..>376
                     /locus_tag="IXR05_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4261451.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINR"
BASE COUNT          144 a           40 c           73 g          119 t
ORIGIN      
        1 taggggtgat tagattatga aacatttaaa aattttgtct attaaagaga cacaacttat
       61 ctatgggggt accactcata gtggaaaata ttatggaaat ggagtgtatt gcactaaaaa
      121 taaatgtacg gtcgattggg ccaaggcaac tacttgtatt gcaggaatgt ctataggtgg
      181 ttttttaggt ggagcaattc cagggaagtg ctaaaatgaa aaaaaatgct aagcaaattg
      241 ttcatgaatt atataatgat atatctataa gtaaagatcc taaatattct gatattcttg
      301 aggttttaca aaaggtatat ttaaaattag aaaaacaaaa atatgaatta gatcccggtc
      361 ctttaataaa tagatt
//
LOCUS       DACGDM010000283          346 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.298, whole genome shotgun sequence.
ACCESSION   DACGDM010000283 DACGDM010000000
VERSION     DACGDM010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.298"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            18..>346
                     /locus_tag="IXR05_003039"
     CDS             18..>346
                     /locus_tag="IXR05_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4261452.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYR"
BASE COUNT          120 a           69 c           69 g           88 t
ORIGIN      
        1 aaggagagtg aacataaatg acttataccc atcttacacc aaacgagctt gtaatgatag
       61 aagcatattt tcatcaagaa actccggttg ctatcgttgc gaagcagctt aaacgtggac
      121 gccaaacaat ttacaatgtc tataactttc tcaaatgtgg tggaacagca cttgaatact
      181 ttgaacaata caaagaaaat aagcgacgtt gtgggagaac cgaaatcatt tttcctgctg
      241 aggaaaaaga atacattgaa aaaagatcaa ctgaaggttg gaccccagac gtcattattg
      301 gccgtgcaga gcgaaccttc tcttgttcag taagtaccct ctatcg
//
LOCUS       DACGDM010000284          343 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.299, whole genome shotgun sequence.
ACCESSION   DACGDM010000284 DACGDM010000000
VERSION     DACGDM010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.299"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(<1..321)
                     /locus_tag="IXR05_003040"
     CDS             complement(<1..321)
                     /locus_tag="IXR05_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4261453.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHL"
BASE COUNT           96 a           55 c           63 g          129 t
ORIGIN      
        1 taaatggata atagtggttt ccaatgtatc gtttgttctt ttgtaggctg gtaaagtttg
       61 ttgtttaaac tcaccattac gatctctagg tatttccaat gttaattcac catattcggt
      121 tttgattgat cgaaagtaag aaccgtttct cgaattacct gaattaaaac cagtgcgatc
      181 atatttttcg taatctaaaa aagccgttaa ttcagtccgt aggagtgtgt ttatcgcttt
      241 ttctaagtgc gaacggaata attcatttaa atcgccttta gtgactagag tttgcacaat
      301 ttctgtagta aaatcattca tagggaagtc ctcttttctg tga
//
LOCUS       DACGDM010000285          341 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.300, whole genome shotgun sequence.
ACCESSION   DACGDM010000285 DACGDM010000000
VERSION     DACGDM010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.300"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..>341
                     /locus_tag="IXR05_003041"
     CDS             <1..>341
                     /locus_tag="IXR05_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261454.1"
                     /translation="EATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEP
                     DAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNR
                     SDADKYEPTVEG"
BASE COUNT          141 a           50 c           76 g           74 t
ORIGIN      
        1 gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc aacaaaactg
       61 gatgataaat ctgacgctga caaatataat cctgaaggtc aaaaagtgac tacagaattg
      121 aataaggaac cagacgcatt tgagggaatt aagaacaaag aagatttacc aaaagatact
      181 aagtatactt ggaaagaaaa agtagatgtt agcgcagctg gaaataaaaa agggactgtt
      241 gtagtgacat atccagatgg atcatctgat gaagttgaag tagatgttac agtgacagac
      301 aatcgttctg acgccgataa atatgagcca acagtagaag g
//
LOCUS       DACGDM010000286          339 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.denovo.301, whole genome shotgun sequence.
ACCESSION   DACGDM010000286 DACGDM010000000
VERSION     DACGDM010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.denovo.301"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            124..>339
                     /locus_tag="IXR05_003042"
     CDS             124..>339
                     /locus_tag="IXR05_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4261455.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNK"
BASE COUNT          141 a           35 c           55 g          108 t
ORIGIN      
        1 acacttggac aaagttattt aatattaata agtattattg ttttatcagt tgtatttgct
       61 tcttcattaa tgttaatcaa gaagcctaaa gaaatcttat caaaaataag ttaggagaaa
      121 ataatggata tattagaaat aaagaatgta gcatatagtt atgcaaattc taaagaaaaa
      181 gttttgtcag gagtaaatca aaaatttgaa cttgggaagt tttatgcgat agtaggaaag
      241 tcaggaacag gaaaatctac acttctttcc ttacttgctg gacttgataa acctcaaaca
      301 ggaaaaatat tgtttaagaa tgaagatata caaaataaa
//
LOCUS       DACGDM010000287        21261 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.038, whole genome shotgun sequence.
ACCESSION   DACGDM010000287 DACGDM010000000
VERSION     DACGDM010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.038"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            120..1433
                     /locus_tag="IXR05_003043"
     CDS             120..1433
                     /locus_tag="IXR05_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAQ4261456.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            1423..2076
                     /locus_tag="IXR05_003044"
     CDS             1423..2076
                     /locus_tag="IXR05_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4261457.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            2131..2682
                     /gene="radC"
                     /locus_tag="IXR05_003045"
                     /pseudo
     CDS             2131..2682
                     /gene="radC"
                     /locus_tag="IXR05_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
     gene            2813..3898
                     /locus_tag="IXR05_003046"
     CDS             2813..3898
                     /locus_tag="IXR05_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4261458.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSEEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            3895..5787
                     /locus_tag="IXR05_003047"
     CDS             3895..5787
                     /locus_tag="IXR05_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4261459.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNMDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            5794..6171
                     /locus_tag="IXR05_003048"
     CDS             5794..6171
                     /locus_tag="IXR05_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4261460.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            6325..7107
                     /locus_tag="IXR05_003049"
     CDS             6325..7107
                     /locus_tag="IXR05_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HAQ4261461.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(7233..7964)
                     /gene="erm(A)"
                     /locus_tag="IXR05_003050"
     CDS             complement(7233..7964)
                     /gene="erm(A)"
                     /locus_tag="IXR05_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HAQ4261462.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(8022..8109)
                     /locus_tag="IXR05_003051"
                     /pseudo
     CDS             complement(8022..8109)
                     /locus_tag="IXR05_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ErmCL family antibiotic resistance leader
                     peptide"
     gene            8473..9135
                     /locus_tag="IXR05_003052"
     CDS             8473..9135
                     /locus_tag="IXR05_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4261463.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
     gene            9370..9513
                     /locus_tag="IXR05_003053"
                     /pseudo
     CDS             9370..9513
                     /locus_tag="IXR05_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            9663..9863
                     /locus_tag="IXR05_003054"
     CDS             9663..9863
                     /locus_tag="IXR05_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4261464.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(10117..11796)
                     /locus_tag="IXR05_003055"
     CDS             complement(10117..11796)
                     /locus_tag="IXR05_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4261465.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11798..12010)
                     /locus_tag="IXR05_003056"
     CDS             complement(11798..12010)
                     /locus_tag="IXR05_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAQ4261466.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            12403..14133
                     /gene="efrA"
                     /locus_tag="IXR05_003057"
     CDS             12403..14133
                     /gene="efrA"
                     /locus_tag="IXR05_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAQ4261467.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            14130..15890
                     /gene="efrB"
                     /locus_tag="IXR05_003058"
     CDS             14130..15890
                     /gene="efrB"
                     /locus_tag="IXR05_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAQ4261468.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            15985..16182
                     /locus_tag="IXR05_003059"
     CDS             15985..16182
                     /locus_tag="IXR05_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261469.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            16335..16820
                     /locus_tag="IXR05_003060"
     CDS             16335..16820
                     /locus_tag="IXR05_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAQ4261470.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(16924..17517)
                     /gene="clpP"
                     /locus_tag="IXR05_003061"
     CDS             complement(16924..17517)
                     /gene="clpP"
                     /locus_tag="IXR05_003061"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAQ4261471.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            17697..18224
                     /locus_tag="IXR05_003062"
     CDS             17697..18224
                     /locus_tag="IXR05_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAQ4261472.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            18315..19052
                     /locus_tag="IXR05_003063"
     CDS             18315..19052
                     /locus_tag="IXR05_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4261473.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            19056..19973
                     /gene="miaA"
                     /locus_tag="IXR05_003064"
     CDS             19056..19973
                     /gene="miaA"
                     /locus_tag="IXR05_003064"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAQ4261474.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            19975..21204
                     /gene="hflX"
                     /locus_tag="IXR05_003065"
     CDS             19975..21204
                     /gene="hflX"
                     /locus_tag="IXR05_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAQ4261475.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         7093 a         3428 c         4419 g         6321 t
ORIGIN      
        1 agagtcaata aagtagttga taaaatcgtt cctctctctg tttcttttct ctttgtcata
       61 cttttatttt tcttatgtgt tctatttgtt ataataaaag agaaatgggg gaattgttga
      121 tgacgattga agaagcaata gaatggatcc atagtcgatt accatttggt tcacgtcctg
      181 gccttgaccg agtcgaagct ttattagaag tggtagggca tccagagaga aaagtaaaaa
      241 cgatccatat cgctggaaca aacggaaaag gttctactgt agcttatttg agaagcctat
      301 tagaagaggc tgggctgaca gtaggtacat ttacttcacc ttatatcgaa acgttcaatg
      361 aacggatcgc aatcaatggc aaaagcattc cagacaatga tttgatccag cttgtaaaaa
      421 aatatcagcc actgatcaaa caacttgatc aatttgaagc agtagctggt attactgaat
      481 tcgagacatt aacagcaatg gcatttgatt attttttgat gaagaaagtg gacgtagcga
      541 ttatcgaagt tggcttaggc ggcttattgg attctaccaa tgtagctgta ccaatgctga
      601 cgggaataac aacgattgga cttgatcata ccgaaatact tggagataca attgaagaaa
      661 tcgctgcaca aaaagctgga atcatcaaac aaggcgttcc agtagtaaca ggaaatattg
      721 ccccagaagc ttttactgtc atccaacaaa cagctaaagc aaaaaatgca ccgctttatg
      781 tatacgggga aaattataaa ataaactatc tgcatcctga tgagatgtgg ggagaagtat
      841 ttgaattttt taatgaaata ggaaagatcc ctcaattaac cactccgctt ttagggcaac
      901 atcaagctga aaatgcagga gtagccatcg aattgtattt tgtttactgt caattggaaa
      961 agctgccttt ccgagaaaaa gatgttttga agggattgaa gaaatctcga tggccaggaa
     1021 gaatggagcg tttgagtaac gagccattag ttgttttaga tggtgcccat aatacgcatg
     1081 caatgaaccg gcttgttgag aatttgaaaa aagaattcaa aggatatcaa atcaacattt
     1141 tgttttccgc cttacgaact aaaaatgtta gagaaatgct agaacgattg cagcaagtac
     1201 caaatgtcca tatttatttg acgacctttg aacatccaaa agccatcgaa ttaagtgaag
     1261 tatcagattt agcaagtgag agagtatcaa tcgtttcatt gtggcaattc ggattagcag
     1321 atatattgga aaagatgaca aatgaagacg tattagttgt gaccggttca ctttatttca
     1381 tttcagaagt tcgccattta ttaatacaat taggaggaga tcatgaagta taatgcagtg
     1441 atttttgaca tggatggttt gctgttcgac acagagttag tgtattacga agccacacaa
     1501 gtagtagcag acaagatggg ttttccttat gataaagacc tgtatttaaa attcttaggt
     1561 gtttcagatg aagaagtatg ggcgaattat catatgattt tctcggaatt tggcaaaaca
     1621 agtgtacaaa gattcataga tgattcatac caggaaacgc ttgaacgttt ttcgcaagga
     1681 gcggtacaaa tgaagcccgg tgtgttggaa ctcctctctt ttttagaaga acatcagatt
     1741 cccaaagttg tcgcttccag taaccaacga gcagtcattg aacttttatt gaagaagaac
     1801 aatctgtttg aacgatttga gacgattgtt tctgcagaaa atgttcaacg agcaaaacca
     1861 gacccagaaa ttttcttgtt agctaatcag aagctaggta cagcgaagaa agaaacattg
     1921 attttagaag attcacaaaa tggtatttta gcagcttctg cggctgagat cccggtagtc
     1981 atggtaccag atctgcttcc accatcccaa gaattgatca aaaaaacagc tggggttgtt
     2041 tcttctttac atgaaatccc tgcattgtta aaataaaaat ccatctcttt tcgtatctta
     2101 ttttagataa gatagaaagg agatgttttt ttgggaaaac gattgatcaa agaagtacct
     2161 actagctctt taccaaggga acgtatggaa atttatggcg cggaagcttt atcggatcag
     2221 gagcttttgg caatcttact gcgtaccggt caacaccctt atagtgtgat gtcgattgct
     2281 ggaaatctgt taaaaacgtt tggaggactg gcctctttac gacaggctac tttgcatgag
     2341 ttagaagaga ttcgagggat aggacgcgtg aaagcaatcg aaatcaaagc cttgatcgaa
     2401 ttaggtcgac gaattcagac ggatcatgaa agagcggctc caccggttcg taccagctac
     2461 gaattggccc agcaattgat tctggaaatg aaagatcaca aacaagaaca tttggtttgt
     2521 atttatttgg acacgaagaa tcaagtgatc ttaaaaaaaa cagtgttcat cggttcgctg
     2581 aatcagtcag tcgctcatcc tagagaaatt ttccattatg ctgtacgtta ttgtgcagca
     2641 aggatcgttt tagcgcataa tcatccttct ggtaatgttt taaccatagt ataataaata
     2701 atagtagtta aagtagttta agaggagata ttaaagggat attttacttt aaataaaaat
     2761 taacaaggtt tataatttgt agtagttaaa gtatttaaag aggtgggaac atgtgaaggt
     2821 tcaaaggata gaagtggaga ataagccgta tccattgtat ttattactag ataaagaata
     2881 ccagctaata gaaccagtaa tgaaatttat taaatactta gataatactg gtaagtctcc
     2941 taataccatt aaagcatact gctatcattt aaagttgctg tacgagttca tggaacagag
     3001 aggtgttatt cttaatgata ttaactttga gttgttagca gacttcgtag gttggttgag
     3061 atatccttca gcatcaaatg taattgatct tcagtcaaaa aaagccataa gagaagaaac
     3121 gacagtgaat acaattttaa atgtagttat gagttttctt gattatttaa gtagattagg
     3181 agaatttaaa tcaattgatg tatttaaaca agcaaaggga agaaatttca aaggattttt
     3241 acatcatgtt aataagggta gataccaaaa gaatgtctta aagttaaggg ttaaaaagaa
     3301 acagataaga acattgagat cagaggaagt taagcaaatt attgatgctt gtcatacgaa
     3361 aagagataaa ttaattttaa tgcttatgta tgagggtggt ttaagaatcg gtgaagtgtt
     3421 atcgcttagg cttgaagata ttgtcacttg ggacaatcaa atccatttaa cacctagaga
     3481 tgttaatgtt aatgaagctt atattaaatt aaggaaggaa agaacaatac atgtgagtaa
     3541 agaacttatg tcactttata cagattactt gatatatgag tatagtgagg aattggagca
     3601 tgattatgtt tttatttcct taaaagaagg ctattttggg aaaccactaa agtaccaaag
     3661 tgttcttgat ctagttagaa gaatagttaa aaggactgga atagaattta catcacatat
     3721 gcttcgccac actcacgcaa cgcagctaat tagggaagga tgggatgttg cgttcgttca
     3781 aaagagatta ggtcacgcac atgttcagac aacgttaaat acctatgttc atctttcaga
     3841 tcaggatatg aaaaatgagt ttaataaata cctcgagaga aaggagcata agaaatgaat
     3901 gcttctagta aaaggaaaat tattagtcag agtgagatta gcaaaaaaat agctgtaatg
     3961 aatgaagaaa tgcaggggtt ttgggctaat aatagttggg atataagaaa atgtccacat
     4021 ccttctgcca tagaattaag taagaatcct gctttaagga atcgttgggt tcgttttgaa
     4081 cgtgttaaaa atctgtggtt aagaacagaa ttgaaatatt tttattttta ccatttaaac
     4141 aatggaatat ggaatgcaaa aactgtctgg attagaaaag gaacagtaat taataaaatg
     4201 ttagatttct tagatttaaa gtatcctagc attacttcaa ttactgaagt tcctattgaa
     4261 aaagcaatga cggagtatag aacttatttg acaaaacggg gtgttagaat taccactact
     4321 aattataaga ttactgctaa tcaagaaaaa acacctgtaa aagctaattc ctactatgtt
     4381 actaatctaa aacaatttat ggagttttat gagaactttt attttgatgg agaggagtgg
     4441 gataaagacg tttgggatag acgtaactta cctttgccag atgataaggt taacccaaca
     4501 caatatgaat atacaattaa ctttaaaggg tttcggaata catattttaa acaacttgta
     4561 aaaagatatt gtaagttgag attgaacatg gatagctttt cctatgtaag tgatattgcc
     4621 caaagactta aagagttctt taattttctg gacatgaaat ttaaacaagt tcagagagta
     4681 caccaattaa cgagagtgga aattgaagca tatttaagtg aactaaacat gatgggaata
     4741 aaacctagta caataactgg gaggatctct atattggaag gactatttag tacccttctt
     4801 aggctagaat gggatgatgt tccttccaaa atattaattt attctgagga ctatccgaaa
     4861 ataccaagag caaaaccacg ctttatagat gaattcgtcc tagagcaatt gaacagtcat
     4921 cttgataaat tacccgaata tatagctacg atgactatga ttgttcaaga atgtggaatg
     4981 aggataagtg aattgtgcac cttgaaaaaa ggctgtctat tagaggacaa agatggagat
     5041 ttctttttaa agtattatca atggaaaatg aaaaaggagc atatagttcc aatatctaaa
     5101 gaggtagctt tacttattaa agttcgggaa gataaagttt cagaggaatt tccagatagt
     5161 gaatacctct ttccaagaaa agatggatcg ccattaaaac aagaaacatt tagaggtgag
     5221 ttaaataaat tagcttatga gcaaaatata gtggataaat caggtgagat ttatagattc
     5281 catgcccatg cctttcgcca tacagtagga acaagaatga ttaacaacgg gatgccccag
     5341 catattgtgc agaaattttt ggggcatgaa agcccagaaa tgacaagcag atacgctcat
     5401 atctttgatg aaactctaaa aaatgaattt actaaatttc aggaaaaact ggttaccaat
     5461 aatggagatg tgcttgatct agatgaagat aatgaagtcg atgatgtaga gcttcaatgg
     5521 ttcaagaaaa atataaatgc acaagtgctt ccaaatggtt attgtagatt gccagtagta
     5581 gcaggtggtt gtccacatgc gaatgcatgc ttagattgca ctcacttctg taccagtaag
     5641 caattcttac cacagcacga agaacagtta gagcgtacag aagagttatt agccatagct
     5701 aaggataaac aatggcaaag acaagtagag actaatagcc gtgttaaaga gcgtttagaa
     5761 caaatcattg gaagtttgac ggggtaatta tcaatggata aacaagttag aaatacaaca
     5821 gaaattgtac gtttggcgaa gcagaaatca aaaaagacaa gggaaaaagt agacaaagcg
     5881 atttctaaat tttcgattga aggtaaagtt attaatttta attcaatagc aaaggaagct
     5941 aatgtttcta aatcatggct ttataaggaa cacgatatta ggcaaagaat cgaatccctt
     6001 cgtgagcgtc aaataacagc aaatgtagtc tcaaaaccca agaaaagttc tcgttcggag
     6061 gaaatcctta ttaaaacctt aaaaagaaga gtaatggaat tagaaaaaga aaataaaaaa
     6121 ttacagaacc aaattcaaaa attatatgga gatctgtata ataaagaata attattaatc
     6181 tgtagacaaa ttgtgaaagg atgtacttaa acgctaacgg tcagctttat tgaacagtca
     6241 tttaggtata tgtccaatct agggtaagta aattgagtat caatataaac tttatatgaa
     6301 cataatcagt tacgaggtga aatcatgagc aatttgatta acggaaaaat accaaatcaa
     6361 gcgattcaaa cattaaaaat cgtaaaagat ttatttggaa gttcaatagt tggagtatat
     6421 ctatttggtt cagcagtaaa tggtggttta cgcattaaca gcgatgtaga tgttctagtc
     6481 gtcgtgaatc atagtttacc tcaattaact cgaaaaaaac taacagaaag actaatgact
     6541 atatcaggaa agattggaaa tacggattct gttagaccac ttgaagttac ggttataaat
     6601 aggagtgaag ttgtcccttg gcaatatcct ccaaaaagag aatttatata cggtgagtgg
     6661 ctcaggggtg aatttgagaa tggacaaatt caggaaccaa gctatgatcc tgatttggct
     6721 attgttttag cacaagcaag aaagaatagt atttctctat ttggtcctga ttcttcaagt
     6781 atacttgtct ccgtaccttt gacagatatt cgaagagcaa ttaaggattc tttgccagaa
     6841 ctaattgagg ggataaaagg tgatgagcgt aatgtaattt taaccctagc tcgaatgtgg
     6901 caaacagtga ctactggtga aattacctcg aaagatgtcg ctgcagaatg ggctatacct
     6961 cttttaccta aagagcatgt aactttactg gatatagcta gaaaaggcta tcggggagag
     7021 tgtgatgata agtgggaagg actatattca aaggtgaaag cactcgttaa gtatatgaaa
     7081 aattctatag aaacttctct caattaggct aattttattg caataacagg tgcttacttt
     7141 taaaactact gatttattga taaatattga acaatttttg ggaagaataa agcgtcctct
     7201 tgtgaaatta gagaacgctt tattacttta atttagtgaa acaatttgta actattgaaa
     7261 atagaaagaa attgttcctt cgatagttta ttaatattag tgacatttgc atgcttcaaa
     7321 gcctgtcgga attggttttt agtgaaaaga acacgatatt cacggtttac ccacttataa
     7381 acaaaagatc gatacttttt gtagtccttc tttgaaatca atggttgatg tcgttcaaga
     7441 acaatcaata cagagtctac acttggctta ggatgaaaat atagtggtgg tacttttttg
     7501 agcattttta tatccatctc caccattaat agtaaaccca aagctcgttg cagattttgc
     7561 aatcttttcg caaatccctt ctcaacgata agatagctat atttagcctg actttcaaag
     7621 gtaattcttt tgacaatatc cgtactgatg ttataaggaa tattaccata tatcttatag
     7681 tttatatgtt ttgggaagga aaattttaga atatccgttt gaatcacttt tatattctca
     7741 gaggggttta ccgcttcttt agtcacttga cataagcctc catcaatttc tatagcagta
     7801 actgatcgac tcattttgac tagctctttg gtaaaatgtc cttttcctga tccgatttct
     7861 attacgttgt cttgtttact gatattcgtg tgattcaata tttcttttac atgcttttta
     7921 gaagtaataa aattttgcgt gtctttaggg tttttctggt tcattataac cttctcctta
     7981 ctggttataa tgaactgaca ttaagcgttc attataacca attaattttg atttggttga
     8041 taacgaactt tattaataac aaatatagaa aaagtaccca tacttttatc tcctttccat
     8101 ttttttcatt atgaatgaga taaagtaatt tctactactg cgatactggt gcacataatt
     8161 gaaacctcct tatgtaactg aatatgattg tatcatcttt tcattttaga ataaaccttt
     8221 atatgtaatt ttgcacttga cacttcagat ggacgttttc ttcaaaataa tatgttttga
     8281 aacttgataa gagaagccac tgtctttact aaaaagtaaa ggctgcgata aaggacagtg
     8341 actttaataa agttgcactg ttgtattgtc tttggataaa attgtctaaa gggaagtttt
     8401 atccccaacg aaaaaacatc taaagtggta agtaatgaaa gaatgtcgat aaagtaggaa
     8461 tgggggatct ttttgaatac aatagaatca cagtttgata aggttgcaga agattacgat
     8521 ttcgtgaatg agcttttgaa tgattattca ttctttgtgt ctaatatgtc tccaaagaaa
     8581 ggcagagcat tagatatcgg atgtggctcg ggtttgttag tggagaaatt agcaagttat
     8641 tatgatgaag tggtagggat tgatatttct aatcaaatgc tcgatcttgc caaatctaaa
     8701 cgtcaactaa caaatacggt ctatctgaat atgaatgcag aacaacttaa ttttaatgag
     8761 aagtttgatt ttattgtaag ccgaacaacc tttcatcatt tggatgatat agccagcgta
     8821 atacagcaaa tgaaggaact gttgaatgag gaaggaagaa tagttattct tgataatgta
     8881 tctgaagtcg agacaccgcc tacctatgtt tataaattag gggcaatcca agagttttta
     8941 ccgcattgtt tcaaatttgg aataaaaaat gcgattagaa tttataatca caacacatct
     9001 aaatcatggc ttgagcattt agcttcagat aagtacctat ctgaacaaaa ttattacgat
     9061 ttatatgaaa agttgttgcc tggatgccaa ttccataaaa tgggttgggc aatgggggtt
     9121 gtctggacaa aataacttaa agctgtggct ttgaaaagtt gaatttgtga ttgttttcag
     9181 agctatcggg tgctttagta taaataacaa tgaataaaaa atcagcctgt atcttatgtt
     9241 actattaagt aatttaagat acaggtttta ctatttttga aataagtacc ttccacttca
     9301 aatacatgta ttcaaagtga aagtattgat ttaaatgatt cttttgtaat ttactcttga
     9361 taatatgaaa ttccatcgca gcaggatatg aattttacca aaaggataca aaagtgtgga
     9421 gaaatgatgg ggatcactgt actggaccac ttgatcatcg gacgcaaacg atattttagt
     9481 ttgagagaag aaggaatgat ggaagagaag taagttgctt tcttgcaaaa aaaatgaagc
     9541 aagtgtacaa ttatattgta attttgtttg ggaatagaag ttgaaacatc tgttgcacct
     9601 ctatcgtaca cgagcaatgt tacaatttaa attagtgctt ttggcacgag gaggatatta
     9661 ttatggaaaa cggaacagta aaatggttca acgctgaaaa aggatttgga tttatctcac
     9721 gtgaagatgg aagcgacgta ttcgttcact tctcagctat ccaaggtgac ggattcaaaa
     9781 cattagaaga aggtcaagca gtgactttcg acgttgaaga atcagaccgc ggcccacaag
     9841 ctgcaaacgt tgtaaaagct taattttatc tgtaaatcaa attgatggta gacatcaatt
     9901 tttacgagag aacaaagcga gtaacaaaaa tacctgccac aagagacaat ttctcttgtg
     9961 gcaggtattt ttttgtatga aaaagtaaat aaatttaaga ggctatgaaa gagccacctt
    10021 gtatcaagga ataagaacaa acaaaaatgg cttctcatgt ttttcatttg ttttctctta
    10081 tattcaggac aaggtgctga tttcataacc tcttatttat tcttcatctg gtgtcattac
    10141 cattggcaaa atcattggat gtctttctgt acgttcgaat aagaaaggct gaagcgcgcc
    10201 agtcatcgct tctttcaatt tatattctga acagtcaggt ccattcaaac attctcttaa
    10261 agcgtggaat aagattcgct gagcttcatt gatcatttct cctgattctc gcatgtagac
    10321 aaatccacga gagagaatat ctggaccagc caagatttct tttttcttga tatccactgt
    10381 cgcgacagct aatacaagac cttcttctga aagcaggtga cggtcacgta aaacgacatt
    10441 accaatatca ccgatcccgc taccatcgat atacacatct ccagccacaa aatgcccagc
    10501 aggacgcgca gaatcgctag ttaacgctaa aacatcgcca ttttccatga tgaagcagtt
    10561 ttctgcagga acacctacat cttgtgctag agaagcatgt actttcaaca tgcggaattc
    10621 tccgtggaca ggaataaaat attttggctt catcaaacga agcattaatt tttgttcttc
    10681 ttgtccaccg tgaccggaag tatggatgtt attgattttt ccgtgaatca cttctgcacc
    10741 agcttcagac agcaaattga tcaaatgatt gacacttgtt gtattaccag gaataggtga
    10801 acttgaaaag atcactgtat cgtctggctg gatttggatt tgacggtgag taccattcgc
    10861 gatgcggctc aacgcggcca tcgcttctcc ttgagaacct gtacatagga tcatcgtttc
    10921 attggcaggc aagcgattga tttcgtgtgc atctacaaat gtgccgtctg gaactttgat
    10981 atatcctaaa cgttgaccgt tgacgatggc attttccatg cttcgtccga aaacagcgat
    11041 tttacgacca gttgccacag cggcatctgc tgcttgctgc aaacggaaga tgttagaagc
    11101 aaagctggca aaaatgatac gtccttcgat ttttgaaaag atcttcaaaa tagaatgccc
    11161 aatcgttttt tctgatttag taaatgttgg aatctcagca tttgtactat cagataaaag
    11221 gcacaagact ccttcttccc cgatacgagc cattttatgc aagtttgctg gttcgccaac
    11281 aggagtgaaa tcgaatttga agtctccagt cgctacgata tttccagaag gtgttttcac
    11341 cacgatccct aatgcatctg ggatactatg ggtcgttctg aaaaagctga cagaagtctt
    11401 tctaaaacgg atgatcgtat cttcattgat ctcatggagc tctgcatctc gaagcaagcc
    11461 atgctcatct aatttgtttg tgatcaacgc taatgcgaga ggaccagcat agataggaat
    11521 atttgcttgt ttcagcaagt agggtattcc gccgatgtgg tcttcgtgcc cgtgagtaat
    11581 caccaaggct tttactttgt gtaagttttg tatgatgtag ctgtagtcgg gaatgacata
    11641 gtcaattcca agtaaatcgt cttccgggaa tttgatcccg gcatcaatca aaatgatttc
    11701 atcttggaat tgtaccccat acgtattttt cccgatttca cctaatccac caatagcaaa
    11761 gacgcctgtc tcgttatttt tgatggaaag tttcatatta aaactccact aatgagaaat
    11821 cagcattttc tttttcgtac tctagatgac ttccttctag aagttgaacg aattcaatat
    11881 tgtatggggt attttcttcc acacgttggc gagcgtctac atcgcttttt gcctcaatgt
    11941 aaagagattt tgtttcttcc cgtttagggt tgcgtacttt tgtttcttga taataaactt
    12001 tatagatcat tgttttgtct cctttatctg cgtaaagcag tgatttagct agttgatttt
    12061 tttagacaac acaaaacgag gggacaagcc acctggtttt tcatatgctt tgactagaat
    12121 actggattcg agtcaaagag acaagcctcg tttttgctta tctgttcgga tattttttca
    12181 accgtacctt ctgtataaaa aatatacaac aattaattgt tattctagca taaaacagca
    12241 aataagtata gaaatcaact agattgaaag aaaaaatcaa tgtttatcat cccgctataa
    12301 tcataatgac ttttttatga gagaagtgtt ctattaatag gctcgttgtg ctatcatttt
    12361 tagtaatgaa aatgtaacaa aagattaaaa ggagatgaga aagtgaaact aatgtggcat
    12421 tataccatgc gttataagaa attcttgttt ttcaatttca tatgcgtatt tggttttatt
    12481 ttgattgaat taggacttcc tacgatttta gcacgtatga tcgatgtagg aatccgcaat
    12541 gatgattttg attatgtgaa gcaacaaggg atatttatga tcgttattac tgtaatcggt
    12601 attattttga atatcttgtt aggttatttt ggttcgagga ttacgactaa tatcgtagca
    12661 gatattcgag atgatttgtt cgaaaagatc caaagttatt cgcatcagga atacgaaaat
    12721 ctaggcgtat cttcattgat cactcgtaca acaaacgatg cttatcagat catgttgttc
    12781 ctgcaaaata ttttacgtat cggttttatg gcaccaatga tgttcattgt cagtttgtac
    12841 atggtcatgc gtacaagtgt gacactcagt ttgtatgtag taggtgcatt acctttacta
    12901 ttattggcag tcgtagcgat tgctaaggtg tctgaaccgt tatctaaaaa gcaacaaaaa
    12961 aacttagata aaatcaacag tatcttgcgg gaaaatcttt caggattgcg tgtgattcgt
    13021 gcattcgtca atgaaaagtt tgaagaaaaa cgttttgctg tagtcaatga gaattatgct
    13081 tctagttcaa aaagcttatt ccgtttgatg gctgttgcac aaccgggttt ttatttctta
    13141 tttaatatcg taatggtatt gatcatctgg agcggggcag tgcaaatcga tgcaggcgag
    13201 cttcgtgtag gagatttgat tgcgtttatc gagtatatat tccatgcctt gttctcattc
    13261 atgttatttg ctagtgtgtt catgatgtat ccaagagcag ctgtttcagc tggacgtatc
    13321 caagaagccc tagatgccaa accttcgatt gtagaagatc caaatggtat atctgataca
    13381 aaaactaaag ggtatatcga atttcaaaat gtaacatttg cttatccagg ccattcgcaa
    13441 gagccagtga tacgaaatgt cagttttaca gcctctccag gagagaccgt tgcttttatt
    13501 ggaagtaccg gtagcggaaa atctacgttg atccaattga tccctcgctt ttatgatgtg
    13561 agtgaaggaa agatcttgat cgatggagta gacgtgagag attatcggct aagcaagttg
    13621 cgagataaga ttgggtttat tccgcaaaaa gcgctgctat ttactggaac gattgcagat
    13681 aatttgcgat acgggaaaga agatgctacg caagaagaaa tggaacgtgc agctgagatt
    13741 gctcaagctt cagaattcat ttctcgaaaa ccagatggat ttaatgaaca tttatcagaa
    13801 ggtggttcca atttttcagg tggacaaaaa caacgattgg caatagccag agccatcata
    13861 cgccgtccgg aaatctatat ttttgatgac agcttttctg cattagatta tcaaacggat
    13921 gcgaagttac gtgctcgtct gaaaaaagaa acgacagaat ctactgtatt gatcgtagca
    13981 caacgtgtgg gaacgatcat gcatgcagat aagatcatcg tattaaatga aggagaagtc
    14041 gtcggtatgg ggacgcatcg ggagttgttg gaaaaatgcc cgatttatta tgatattgcc
    14101 gcttctcaat tatcaaagga ggaattagca tgaaaaaaac cttttcttcc ttaaaacgtt
    14161 tagctcgata tatcagaccg tatcgtgaga cttttctttt agtgatccta tttacagttc
    14221 tgacagtggc tttcaacgtg gctttgccat atgttacagg acttcctact acagaaatca
    14281 gccgtaatat tgccaatggc gaatcaatca atttttctta tatattcaaa tgtctcattt
    14341 ggatcacagt tgttggaata gggtattgta tttcgcaatt actttctggt gttttgatga
    14401 caaatgtcgt tcaaagtgcc atgcatgatt tgagaagaga catagaagaa aaaatcaatc
    14461 gtcttccggt ttcatatttc gataaaaacc agcaaggaaa tattttgtct cgtgtgacga
    14521 atgatgtaga tgcagtcagc ggtgctttac aacaagcttt tattggtatc gtaaatgcga
    14581 tattgggaat tacgttggct gcagcaatga tgttttatat ccagccgatg atggcgctga
    14641 tctctatgat catgattcca acatcgatct ggatctcaaa acgagtgatc aatgcttcgc
    14701 agaaatattt tcaaagcatg cagaattctc ttggtgagct aaacggctac gtccaagaaa
    14761 atatgacagg ttttagtgta ttgaaagtat atggacgcga aaaagaaaca ttggaaggat
    14821 tcaaaaaagt taatcacagc ttgaaatact ttgggtttcg tgcagcattc atttctggct
    14881 tgatgatgcc tctagttcaa ttaactgcct atgctactta tattggtatg gctgttctag
    14941 gaagctttta tgttattact ggggcgatcg ttgtcggtca actacaagca ttcatccaat
    15001 atatttggca aatcagtcag ccaatgggga acgtgacaca attgtcttca gttttgcaaa
    15061 gtgcatcagc ggcaacgaaa cgtgtattcg agattttaga tgagccagaa gaaaaagaaa
    15121 acaaagtaga tgcttcactg ccagaaacga ttttaggaga tgtgacattc gatcatgtcg
    15181 attttgcata tgatccgaag aaaccattaa tccaagattt gaattttgaa gtgaaagctg
    15241 gtcaaaccgt agctgtggtc ggtccgaccg gtgccggcaa gacgacattg atcaatctat
    15301 tgatgcgttt ttatgacgta gacaaaggag caataaggat tgatggaatc gacaccaaat
    15361 caatgagtcg cagtgatgtg cgttcgctat ttggtatggt cttgcaagat gcatggcttt
    15421 atcaaggaac gattgcagat aatatccgct tcggaaagct tgatgcgaca gattatgaag
    15481 tagttgatgc tgcgaaaaca gcaaacgtag atcattttat ccgaacgatg ccagatggat
    15541 atgatatggc catcaattct gagggagaca atgtgtcttt aggacaaaaa cagttgctga
    15601 cgattgcccg agcagtggtc tccgatccta aaatcttgat tttagatgaa gcaacaagtt
    15661 cagtagacac ccgtttagaa gcgttgattc aaaaagcaat ggatcgcgtg atggagggac
    15721 ggacaagttt cgtcatcgct caccgtttat cgacaatccg tgatgcagat ctgattctag
    15781 tgatggatca aggtcagatc attgaaaaag gaacgcatga gagtttattg gcacaaggtg
    15841 gattttatga aaaactgtat aacagccaat ttgctgagga agcagaataa gtcatataag
    15901 aataaaacag tttaaaactt attttttgtt ctctattctt gataatggta aagtaaagtt
    15961 atcaagaaaa gtgaggacac ggagatggaa cagtttttaa atgaaaaaat tactgaagcc
    16021 aaaagagaag ttgatcgttt aacgcacgtc tgtcagacga agccttttga ttcagctgat
    16081 ttttttgaaa atgagtttca aatcgaacgc ttggcagcac aaatagaagt gtacgaatta
    16141 attttaaaaa aagtaataga agaaaatata gatgtacaat aaaaacaggt aaaacgtcag
    16201 ttaccagata ctgtaaatag acatctggcc tgagcaggtt ttacctgttt tttttcttat
    16261 gaaataaata tatgctatga tacctttatt caataggatt agtttctaca aaaaatgaaa
    16321 ggagaaaaat aaatatggaa cggtttatag catcaaatgc cacagtgatt ggtgatgtga
    16381 cattgtcaga agatgtgacg atctggtatc aagctgtttt acgcggggac agtaattgga
    16441 taaaaatagg acaaagaacg aatatccaag atggtacaat catccatgtc gatcatgatg
    16501 cacctgtaga tattgcggag aatgtgacgg taggacatca gtgcatgcta catggctgta
    16561 caatcgaaaa aggggcgctg atcgggatgg ggaccacgat attgaatcat gcggttattg
    16621 gtgagaatag tttgattggt gctggatcat tagtaacaga aggaaaagtt attcctccta
    16681 atgtcttggc ttttggtcgc ccagctaaag tgatccgtcc tttgacaaaa gaagaaatac
    16741 aaaaaaacaa agaaaacatc cagcattatg tcgagatagg tcggatgcat gcgcaaggaa
    16801 aattcaagga gcaaagatag gcagtagcat ccataaaata aaaaaggatg gtcagtttga
    16861 gttgaccatc cttttttatt tggtttagat aagagagctt aaaaaagctt cctttgaaac
    16921 agattaattt aatgaagaac tgttttccat gacttcatcg atcaatccat atgcttttgc
    16981 ttgttcagct gtcatatagt tgtcacgatc tgtatctttt tcaatcactt caagcggttg
    17041 tccagtgcgt tcagctaaaa ttttgtttaa gcgttcgcgt gtttgcaaaa tatggcgtgc
    17101 cgcaatttcg atttcagttg cttgcccttg agcgccgcca agaggttgat ggatcatgat
    17161 ctcagcattt ggtaaagcaa atcgtttacc ttttgtacca gctgtcagca agaagcttcc
    17221 cattgaagca gccataccca taacaattgt ttggacatct gctttgacaa agttcattgt
    17281 gtcgtaaata gccatacctg ctgtaactga accaccagga gaattgatat aaagatagat
    17341 atctttttca gaatcttgag cgtctaagaa aagcaattgg gcgatgatcg aattagcaag
    17401 atcatctgtt acttggccgc ttaacatgat gatacggtct ttcaataaac gtgagtagat
    17461 atcgtaagct ctttcacctc gtgaagattg ttcaatgact gtaggaatta aattcataat
    17521 agagttcctc cttgatttcg tttagaaata gtgtaccata atttagtttc taatacctaa
    17581 aatgtagtat acatttttgg tcaaaaaagg tcaaataaaa aacttaggca aattagtcgc
    17641 ataaacccgc tttatggtat gataagcaga gaaacaaaac aaggaggaac aacagattga
    17701 tagttggtat tactggcctt atcggagtgc tgacaggtgc tgtagttgtc tatatcggca
    17761 tgatactgca aatgcgtcac ttggaaaata aagaacagcg tagacgtgaa ttggaattga
    17821 aagtcaaaga aatcgagacg ctgaatcaat taaataaaaa gatcaacgag atcttgcaaa
    17881 aacggacaac gctgatggaa gaatatgtca gctttgatgc atttgatgat tgttatatca
    17941 cgattgacga ttttgcgtat ctccaatcat tttcagcgca aaatagtttt tatctgccaa
    18001 attatatttt agacgagcta tttaagaata tctcccatcg aaaagtgatt ttatctccag
    18061 atgaaacaat gaagattggt ggatatgctt ataaaggcgg acgcgtgatt ttagagaatt
    18121 ttacggatag tctgactgaa atgatcaatg aaaaaaaagc tcagttgaag actatgacgc
    18181 gccagccgat tggtttcttc tcgaaagatg atgtttggag ctgatatttt gaagcattgc
    18241 cgttgcacat gagagcgtgg taatgctttc tttttttctt aatgatacaa tagaactgaa
    18301 cggagtgaag aaagatgtta caaatctatg cccatcgcgg aagcagcggc acccacccag
    18361 aaaatacgct tcctgcattt gcagaagctg tacgagtagg tgcagatggt atcgaactag
    18421 atgtccatct aagcaaagat ggttatttga tcgttatgca cgacgaagaa gtggaccgga
    18481 cgactaacgg taaagggctg attcgagaaa aaacattgga agaactcaaa aaattgaatg
    18541 cagggggcaa attcagcaaa gaatttccag cagctaaagt tcctgaattg agagaagtgt
    18601 taggactgct cctccaaaaa aattaccgag ggatgctaat gattgaaatt aaaactgatc
    18661 agtatgaata tcccggtatc gaagaaaaat tagccgaaac attaaaaagt agagattggc
    18721 cttttcaaca tgcatattgc agctttcatt tggattcttt ggaaaaaatc gcattactgg
    18781 aaccggagat acagctggac ttattgatga gtacttctga taaaaagatc caactagcag
    18841 cagaaacccc ttatatagaa ggagtacatc caaaaaatac ttggttgttc gaacatccag
    18901 tccaggcagc tgattttcca aaagcaattc gtgcatggac gattaacgat gaagaagaaa
    18961 tggccaaatg tcaagaactc aaaatagatg gaataataac tgattttccg gagaaagctc
    19021 ttcggtggaa acaatcaacg aaaagtaggt aaaatatgga aaaagtatta gtgatcgtcg
    19081 gtccgacagc agtcggtaaa acagcgctaa gtgtggaact cgcacaacta tttggaggag
    19141 agatcatcag tggtgattca ttgcaaatct ataaaaatct ggatatcggt acagcaaaaa
    19201 tcaaagaaga agagatgaat aatgttccgc atcatttgat tgatgtgatc gaacctactc
    19261 aacgttactc agccgctgat tttcagcatt caggtcgaca attgattacc gagattgcga
    19321 accgagggca cctacctatc atagctggtg gtacgggtct ctatatccaa tcccttctat
    19381 atgattatca gttaggagcg acagaagaag cgaatcctga gattagaaaa aagtatgaaa
    19441 cgttagctga aacaattggt tcccaagcat tatggaatca gttgaaagaa aaagacccgg
    19501 cagctgctga gaaaatccac tggaacaatc aacgcaaagt gataagagct ctggaagttt
    19561 tagagacgac aggacatagt atcacggcac ctaaagaaga gccaaagcaa ttgtatgatt
    19621 acctcatgat tggattagat acgaagcgta gtattcttta tgaacgaatc aatcaaagag
    19681 tcgatttgat gctagcagaa ggtttagtag cagaagcgcg taaggtgtat gagcttggag
    19741 aagtccaggc cagtcaaggt attggatata aagaattttt cccttatttt gaagggaaag
    19801 aaacattgga agaagcaaca gaacaagtca aactacattc gagaagatac gcgaaacgtc
    19861 agttgacgtg gtttcgtaac cgtttggatg cacagtggtt tgatcttata agtgagccaa
    19921 atcaaaaaag tcagattgag caaacaatca aaaaatggct ggaggcggaa taaaatggaa
    19981 gaaaaagtga tcatcgtagg ggtagaaacc gaagcaaacc agcgttactt ttcagagtca
    20041 atggaagagc tagttcagct gacgaatacc gcatcaggag aagtcgtatt cacaattaca
    20101 caaaagagac cacaagtgga tcggcaaacg attatcggta aagggaaatt acaagaatta
    20161 gttcaacaag cggatgcgca tgaagcggat ttgatcatct ttaatcatga gctaactccg
    20221 agacagagcc aactgattac cgatgctgtt ggtcttccgg taattgatcg cgtgcagctt
    20281 atcttagata tttttgcgat gcgtgctcgt tcgaaagaag ggaagctgca ggttgaactt
    20341 gctcagttag aatacctgct gcctcgttta gtagggcaag ggaaaacatt atctcgtctt
    20401 ggcggtggga tcggaacaag agggccaggt gaaacaaagt tagaaacaga ccgccgacat
    20461 atacggaata aaatttttgc tgttaagaaa gaattgaaag aagtagaagc tcatcgagag
    20521 cgcaatcgcc aaaaaagaaa aaatagcgag atttttcaga ttggacttat tggctacacg
    20581 aatgccggga agtcaactat cttgaatcta ttgacacaag cggatactta ttcgaaagat
    20641 caattgtttg caacgttaga tccattgact aagagatggc gttttgctga aggatttgag
    20701 attactgtaa cggataccgt cgggttcatc caagacctgc ctacgcaact gatcgatgct
    20761 ttccattcta cattagaaga aagtcaaaat atggatcttt tgctacatgt agtcgatgct
    20821 agttctccag atcgtatttt acaggagcag actgtcttaa aattgatgga tgaactgaat
    20881 atgaaagaaa tgccgatact gactgtttac aataaggcag accagatcga cccagcgatg
    20941 ttcacgccta cgctattccc aaatgtattg atttctactc agacgaaaga aggtaagatg
    21001 gcgttgatcg aagcaatcaa acgtcagctg atggaactaa tgacccctta tacactttct
    21061 gtgccaagca acgaaggaca gaaattaagc gagttgagaa gacaaacaat ggttttggac
    21121 gaagcgtaca tggaagaaac aaacgaatat gaagttaaag ggtttgcaaa aaccaattca
    21181 aaatggttaa gaaaaaacca ataaaatttt atttttttaa caatattatt tgtcaaatta
    21241 agcgagacaa aactttccat t
//
LOCUS       DACGDM010000288        14751 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.059, whole genome shotgun sequence.
ACCESSION   DACGDM010000288 DACGDM010000000
VERSION     DACGDM010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.059"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            216..1112
                     /locus_tag="IXR05_003066"
     CDS             216..1112
                     /locus_tag="IXR05_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4261476.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1262..2203)
                     /locus_tag="IXR05_003067"
     CDS             complement(1262..2203)
                     /locus_tag="IXR05_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4261477.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2329..3450
                     /locus_tag="IXR05_003068"
     CDS             2329..3450
                     /locus_tag="IXR05_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4261478.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3708..5210
                     /locus_tag="IXR05_003069"
     CDS             3708..5210
                     /locus_tag="IXR05_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAQ4261479.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5277..5804
                     /locus_tag="IXR05_003070"
     CDS             5277..5804
                     /locus_tag="IXR05_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4261480.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            6015..7076
                     /locus_tag="IXR05_003071"
     CDS             6015..7076
                     /locus_tag="IXR05_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4261481.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            7079..7975
                     /gene="murQ"
                     /locus_tag="IXR05_003072"
     CDS             7079..7975
                     /gene="murQ"
                     /locus_tag="IXR05_003072"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4261482.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7989..9971
                     /locus_tag="IXR05_003073"
     CDS             7989..9971
                     /locus_tag="IXR05_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4261483.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(10036..10482)
                     /gene="nrdI"
                     /locus_tag="IXR05_003074"
     CDS             complement(10036..10482)
                     /gene="nrdI"
                     /locus_tag="IXR05_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4261484.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10693..12117
                     /locus_tag="IXR05_003075"
     CDS             10693..12117
                     /locus_tag="IXR05_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4261485.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(12298..13071)
                     /locus_tag="IXR05_003076"
     CDS             complement(12298..13071)
                     /locus_tag="IXR05_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4261486.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(13068..13973)
                     /locus_tag="IXR05_003077"
     CDS             complement(13068..13973)
                     /locus_tag="IXR05_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4261487.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(14127..14447)
                     /locus_tag="IXR05_003078"
     CDS             complement(14127..14447)
                     /locus_tag="IXR05_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAQ4261488.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         4723 a         2624 c         3110 g         4294 t
ORIGIN      
        1 gcaatattta acaatgacta atgataacaa attttcagac aattacaact attcagaaaa
       61 cttttaggcg aattttaata gaagaatgat ttatttcatc atattttcat acaaatgtta
      121 aattttcata caaatatagg aaacgtttta ctggcttttt actatttaaa caggctatca
      181 taggaaaaag tgacagagaa agtgaggcgg aaaagatgaa caaaaatgac gtactgctag
      241 ttgcaaaaaa taaatcactt tattttttgc cttccatccg ctctttagat gtttggtccg
      301 gaaaagattt actacagtcg gaattcatta aatcagctag acaacagttg gcaaattatc
      361 agctgatcgt ttttttagat tatggatttg atatggagat ggctcgacgc gtgcgcccat
      421 ttaccaatgc aaaaattgtg ttattttttt ggaatcactt caaagcagaa cacgaggcga
      481 tgctgaagca ggcacaagat gaaccggcaa tcgatgagat ttatcatttt gattttttgg
      541 aagcaaaaga acttgggctg aaacataata gttcatttta ttcgaaacat atgaattttt
      601 cttctagcga accaaagacg gatctatttt ttggtgcaac gaataatggg agaaaagaac
      661 gagcagaaag ctataagcag gaatttataa aaagagatgt tacgaccaac tatttcattc
      721 ttccacatcg agggaatgaa caacctggat atcttactta tgaagagtac ctgaaaaaaa
      781 caggggaatc gcgcgggatt ctggaactgt tgcgggaggg tcagcaagga gtgactttgc
      841 ggacatttga atccatgtat tttcaaaaga aactagtgac ggataatcaa gcgattgctc
      901 attatcattt ttatcgtcct gaaaatattt ttttgcttcg agaacgtgat ttagatgaat
      961 taccggaatt tctgcataca ccatttaagc caatcctatc agagctattg gaattttatg
     1021 atgcagaaaa ttgggcaaaa cgatttatca ctaacgattc cactatttat gagcaatacg
     1081 aatatgacct ctcctctgtt gaaaacaaat aaaaaaccta cattttgaag agattatgta
     1141 ctgaaacaaa caagcacaat tcttatggca tcatgagagt tgtgttttct ttttgatctt
     1201 ttattgggct taaaaaaaga gaaccagctg ctgattcagc tgattctcat cagagagcct
     1261 tttattctgc gccaaggatt ccttcttttg catggactaa ttgggtcaaa aaggcacaat
     1321 atggtgtagc aatatcatat ttttgtcctt ttcgccaaat ggcaccattg atgtagtcga
     1381 tttcagtcaa acgatggttt ttgatcaggt cttggtacat agatgggtaa tgcaacccga
     1441 tgttgtcagg atcataagta gaagcaatat gttggtacac ttcttcttga tctagtatga
     1501 ttccttcttt tgctgcgata gaagcaaatt cagatacgat tgttcgaacc atgctctctg
     1561 ccgctttttg cgcgcctagt tcagcaatat tacaatccaa aatcgtgcat aaaccattca
     1621 atgttccatt tacacaagct tttcgccaaa tggaataacg aacgttatgg ctatagatcg
     1681 gatttaaatt tgcttcttga aagacttcta caactttttt tgtaaatgct tcgccttctg
     1741 gttccaagtt ctctagttcg atttctccat cacctaacaa tgtgactttt ccgggaccag
     1801 ctagaccagc tgtccacatc gtgatcccaa ataagatatt tttctttggc acatattttt
     1861 ccagtacatc ttcatgacct aatccattta gtaaacacaa aacataagta ttgtcagtaa
     1921 taatggattg gatcgaacaa aacatatcat ctaattgatt ggcttttgtt aatgctacga
     1981 tcaagtccac gtgttcgttg ctttcgatga tttcttctgg tgaatagatt ggcagttttg
     2041 cgaccacttc tttaccgtta aagtcagcaa tcaacccatt tgtacgaatg gcttcaatgt
     2101 gagcaggcca acgatcgatc aagaggacct catttccgct ttgatgtagc atcaatccga
     2161 ttcggctgcc cattgctccg gccccagcta ttgcgatttt catgtttttt ctctccttta
     2221 ttcaatgagt tcccttttag tatatagaaa aatggaagaa aatagcattg ttttgtttga
     2281 aaaaaatgaa aaaaagtgtc ttacttaaga agaaagtgag ggatacagat ggatattttg
     2341 gcggcaattg attcatttaa aggaagtgct tcttcatttg aactaaatca ggcagttcta
     2401 aatggctggg aagatcgtaa aggaagaaaa atcaatgtgc cgattgcaga tggcggagaa
     2461 aatactgcag aagcaatcta ttacgcgctc aggggaacat ggcgtaccat tgatgggatg
     2521 gatctcttat tccgtcagcg aaaaatcagc tatttattga caacttggca aggaaaaaac
     2581 accgcagtca tcgaatctgc acaagcattg gggttagatc tacttgataa accaacggat
     2641 caaactatcc gacttgcttc cagttatgcc ttaggagaac ttattaaaga tgcactgctt
     2701 caagaagtag aacaaattat tgtcacttta ggaggaagcg ggtgtagcga tggtggtcta
     2761 ggattactcc aatccttggg tgcttcttta gaagggtaca cagaaggaaa tcctttatta
     2821 tctactaaaa aacttcattt tgatcgaaga aacgttcttg tttctaaagt aaaattgatt
     2881 atcgctgcag atgttaccaa tccatataca ggtcaacaag gagctgcttg gcaatttgga
     2941 agacaaaaag gaggaataga tacgacgcta gctttcttag ataaacaagc aggaaagatt
     3001 gctcagcaaa taaaagattt ctgggaggtg gatttagatg atattccagg aagtggagca
     3061 gcaggcggta ttggtggagc cctttttttg ttgggagcga agatggtttc tggtttcgat
     3121 ttagtcagcc aaatcactgg attggaaaaa aagatcgaac aagcagatgt catcattaca
     3181 ggagaagggc ggatcgatca gcaaacgatc cacggaaaag ttccatacgg tgtagcagtg
     3241 cttgcaaaaa aatatcgaaa accaataatc gctatttgcg gaagtagaga ccaagagcta
     3301 gaaggacttt ctgattttct cccaattgtc ttaagtattc atttgggtcc aataggttta
     3361 gaagaagcaa tggaacacag gcaaacatta gaaaaaacaa aaatcttagg acagacactt
     3421 agcagatttt tcaccatcct cccgaagtag ttgacaaaat cattttcttt atgctatcgt
     3481 aatttcaaat ataggacaaa gtgagggatc cgtgcattga aaaattaagt cgattgatga
     3541 aagctgcatt cagactgtac cttgtggaga caaggaagca gtgtgcagat tttcgggatt
     3601 ggcttggttt tttcgatgta tgggtctttt tgtgtgtatc caacccttgc atcctcttta
     3661 gccagttctg aaaataggac tggtcttttt ttacgaggtg atggaaaatg tctaaaatcg
     3721 aaataaaaaa tctgacattc ggctacgaca gccaaggcac attattattt gaacaagcaa
     3781 atctaaattt tgacacacaa tggaaactag gacttatcgg acgaaacggt cgaggaaaga
     3841 caactttact gaatattcta caaaacaaac taccttatca agggcaagta atccatcagc
     3901 aagaatttgc ctatttcccg caacagacaa aagataaaga acgtttaacc tattacgtgt
     3961 taaatgatat tacggatttt gagatatggg aaatcgaaag agagctccaa ttgatgcaaa
     4021 cagatcctga aatcttatgg agagaattca gcacactatc ggggggagag aagacaaaag
     4081 tcctactggc acttttattt gtggatgaca ctcatttccc gttaatcgat gaaccaacga
     4141 atcatttgga tatctctggt agaaaacaag tagcggctta tttgaaaaag aaaaaacaag
     4201 gcttcatcgt ggtcagccat gaccggggat ttatcgatga agtagtggac catgttttag
     4261 caatcgaaaa aagtcaactg gaactttatc aagggaattt ctctatctat gaagaacaga
     4321 aaaaacttcg tgatgaattt gaaatggctc aaaatgaaaa attgaaaaaa gaagtcagta
     4381 ggctaaagaa aacagcagct gaaaaagccg aatggtctcg ttcccgagaa ggagataaaa
     4441 caaagaaaca agtcggattc atcgatactg aatctagacg agtgaataaa ggagcagtgg
     4501 gtgctgatgc tgcacggacg atgaaacgat ccaaagcaat cgtgaatcgg atggagaccc
     4561 agatcagcga gaaagaaaaa ctattaaaag atatcgaata tatcgattct ttgacgatga
     4621 atagccaagc gtctcaccat aagcgacttt taagcgtaga agatcttcaa ttagggtatg
     4681 aaaatctgtt attcgagcca attcatttta caatcgagcc tcatcagcgg gtggcgattt
     4741 caggtcctaa cggtgcagga aagtcatcca ttatccatta tcttctgggg gcattcaacg
     4801 gcaaggttat aggagaaaaa taccagccaa aacatctgag cattagttat gcaagccaaa
     4861 attatgaaga caatcgagga acgttggcgg aatttgcaga gaaaaaccaa gtagactacc
     4921 aagcattttt gaacaacctc cgaaagcttg ggatggaaag agatgttttt cataacaaga
     4981 tcgagcagat gagtatgggc caacggaaaa aagtggaatt ggctaaatct ttatcacagc
     5041 cagctgaact atatacatgg gatgaaccat tgaattattt ggatgtcttc aatcaagaac
     5101 aattagaaca actgatcttg aacgtgaaac ctgccatgtt actagtggaa catgatcaaa
     5161 ccttcctgga taaagtatct actgagatta tttctcttga gagaatctaa cccttgtaat
     5221 ctcaagaaca acaaggtatg gttaagggga actttgccaa cgaaggagag aatcacatgc
     5281 tttatgtaac gagacacgga gaaacaactt ggaacgcaca aggattagtt tgcggacggg
     5341 cagatgtgcc gctgactgaa aaaggacaga tgcaggcaca gaaactagca gaaaaggtag
     5401 tagatttgcc tgttccaatc acgaaaatca tccattcccc tcttcaacga gcaagagata
     5461 cagcacaagc agttgctgat cgtctcagct tgccgctgac cgttgatgaa cgattggtag
     5521 aaatggattt tggggattat gatggactgc caagcaaaga tgagaacttt caaaaagcac
     5581 gtttagcgtt cgctgtacga ttcccaaatg gggagtcagt cttagatgtg tatgcacgga
     5641 tcgttccttt attgaaagaa tgcatcgaag acgaagaaaa tgtctatctg ttagtttgcc
     5701 ataatgcctt gataagagtg atcaatgctt attttcatcc gatgcctaat gaggggttct
     5761 ttacattcat ggtagataat acagaattgg tttcttatga gtaattatgt ttttgtgtta
     5821 tttaaataaa atatttcaag gcactgcttt tgcttagcag tgcctttttt aggttatgac
     5881 aattcttttg ataatataaa ctcaaccttt agaaatgaaa tttaattatt ttaataaaag
     5941 tattgaaatt ttgtttcttt agatatatac tctagtcata gaaatgaaga cggatacaga
     6001 aaaagaggga taatatgttt ggcttttcaa tatttatgaa cgattctttg tcagaagaga
     6061 agaaacagta tatccgccaa atggcatcca atggctttgt cggtattttc acttccatgc
     6121 atataccaga agatgatgtt tcggcatatc aaaagcgatt gatcgaacta ggaagcgaag
     6181 cgaaaaagaa taaactagaa ttgatggtcg atatttcagg agaggcattg gaacgagcgg
     6241 gtttttcatt agaagatcta acgcctttga aagcaattgg tgtaacaggt ttaagaatgg
     6301 attatcatat ttccaatcag cagattgccg actggtcaca tcaattgaaa atcagtttga
     6361 atgctagcac gatcacgcct aaagatatcg atgaattgaa agaagcagaa gctgatttct
     6421 cacagattga agcttggcat aattattatc cacgtcccga aacagggctg gacaaagaat
     6481 ggtatcagaa aaaaaatcaa tggctcaaaa ttcaaggtct ccttgtccaa ggttttgtac
     6541 caggagatac agagttgaga ggcccactat atcaaggatt gccaactttg gaagaacatc
     6601 gagggatcca tcctcttgca ggcgctctag atctattagc aagtaacacg gatattgttt
     6661 acatcggaga tgcaggtctg tcagaaaacg ttcaggagca atttgcttct ttccaaaaag
     6721 aacagacagt cttgctccat acggaacctg tagatgaaga attttacgaa tatatattag
     6781 ggaagcatac gaatcggcaa gacgatgcaa gagatgtcat acgaagcgta gatgcacgtt
     6841 ttcgagagat tccgcctatc ccagcaagaa atacagctac gcgtatgaaa gggtctatta
     6901 ctttagataa cgaaaagtat ttgcgctata tgggtgagat ccaattaacc aaatatgatt
     6961 tgccagcgga tgaaaaagtg aatgtagtag ctaaagttat caaagaagag ctaccattga
     7021 tcaaccaaat caaagctggt atgaactatc aatttataag aaaagaagga agataaaaat
     7081 gagcaaaatc aatttagaga acctaacaac ggaacgcaga aaccaagaaa cttttggatt
     7141 agatgagatg agtatttctc aagccgttca actaatgaac aaagaagatc agaaagtggc
     7201 cgctgcggtt gaaaaagaac tgacaagtat cgaaccagtg attgctaaca cgattgagtc
     7261 ctttaaaaaa ggtggacgtc tgatttatat gggagccgga acaagtggaa gactaggtgt
     7321 gttagatgct gctgaatgcg taccgacatt cggtgtagaa ccggaaatgg tcataggtct
     7381 aattgctggt ggagaagaag caatgactgt agctgtcgaa ggggccgaag attcttatga
     7441 gctagggcaa gaagatctaa tcaagctgaa tttgacaaaa aatgatatag ttattggtat
     7501 cgcagctagc ggtcgtacac catatgtgat cggtggatta gattacgcaa aatcgatcgg
     7561 tgctgtcaca ggaacgattt cttgcaataa acaagccgaa atcagtaaac acgcggattt
     7621 cccaatcgaa gtcgatgcag gtccagaatt tttgacaggc tctactcgat tgaagtcagg
     7681 aacagcacaa aaacttatct tgaatatgat ttctactatc agtatgattg gtataggtaa
     7741 agtattcaat aacttgatgg tcgatgtcaa accaacaaat gaaaaactaa tcgaacgctc
     7801 aaaacgaatc atcatgcaag cgacagaagc tgattacgaa acagctgaaa agtactttga
     7861 agaagcagat caaaatgtta agctggctat cgtcatgatt ttgacaaata gtgataaaga
     7921 ggaagctcaa gcaaaattag ctgaagcaaa cggatttgta aaagggacct tatgaggggg
     7981 aaaagaccat ggcaaaaaac gaactgactt tggaagaact ggcaaaacaa atttataaag
     8041 gggcaggcgg catgggcaat gtagaaagca ttgtccactg catgactcgt gtgcgtatga
     8101 agatcatcaa tgatgatctt gtaaatgtct ctgaattaaa agcgattcca ggagtgcttg
     8161 gtgtagtaga agatgaacag cttcaagtca tcatcggacc tgggaaagtg aacaaagtag
     8221 cacagcaaat ggttgatttg gcaggcgtga aattaggaga aaaactttct tctgtaagta
     8281 cagctacagc aaattcatca gcatctggaa aagaccgtgt aaacgaacgg gcacaagaaa
     8341 tgaaagcggc acaaaaatcg aaacaaaaac catctaaaat caaatcggta ttaaaagaca
     8401 tttctaatat ctttgtgcca atgattcctg catttgtcgg tactgggatc gtggcaggga
     8461 ttgccgcagt tttagcaaac ttagtcacag ccggaacact tgatgcagca acatggcaac
     8521 aatatatcga tgtgatgaac atcttgaaaa acgggatgtt tagctaccta gttatctata
     8581 caggtatcaa tgctgcacaa gtttttggtg caacaccaac tcttggtgga gttatcgggg
     8641 ccgttgtgat gctgacaggg atgaatccgg aagcaccact gaaaaactta tttactggtg
     8701 aagctcttgc agctggacaa ggtgggatcc taggtgtcat cttcgctgtt tggctattgt
     8761 caatcgttga gaaaaaactg cataaagtag tacctgatgc ggtagatatc atcgttacac
     8821 caactctttc attgattgcc atcggtctga ttgaaatttt cttcatcatg cctttagcag
     8881 gtttcatttc tgatggcatg gtcggtggga tcaactgggt acttggcgtt ggtggagcat
     8941 ttgccggctt cgttctaggc acattattct tgccgatggt tatgttcgga ctgcatcaaa
     9001 ttttgactcc aatccatgtg caaatgattg atgaaactgg tcgtacgcta ttgcttccaa
     9061 ttcttgcgat ggctggtgca ggacaagtgg gtgcagcatt ggcattatgg attcgctgca
     9121 aaaaagataa agaattaaca gaaatgatca aaggagcttt accagtcggg atcctaggaa
     9181 tcggcgaacc attgatttac ggagtaacat tacctctagg acgcccattt attactgctt
     9241 gtatcggtgg aggtatcggc ggggcagtga tcggaatgat cggaaatgtc ggggctatcg
     9301 ctattggacc ttcaggagcc gctttgatcc cattgatctc tgacggtaaa tggttaggct
     9361 acatccttgg attattggca gcttatgctg gtggcttcgt tgctacattc ttcttcggta
     9421 ttcctaaaga ccgtttagaa aaagaagaat tagcgactga aacagccaca gtaaatgaag
     9481 tgcctgaaaa agtagtacct caaacttcag ctgaaagtgt gactatcctc tcatcagttg
     9541 ctgacggaac agttgtttct ttagataaag caagtgatcc agtttttgca caaaagatga
     9601 tgggtgaagg ctactttgta gaaccagaaa acggacatat ctattctcca gttactgggg
     9661 tagtcagctc tgtcttccca acgaaacacg ctattgggat cacaacgcca aatggtttag
     9721 aaatcttgct tcatatggga atcaacacag ttgacttagg cggtacgcca tttgatgtga
     9781 aagtaacaga agggcagcaa gtgacacctg atacgcttgt agcagaagct gacttagaag
     9841 cgatcaaagc agcaggcaaa gaaacatcca tgatcgtctt ggtaaccaat atggatcgtg
     9901 taaaaaactt tgtcttggaa aaaacaggta aagcaaaagc aaaagcacct gtgatggatg
     9961 tcaaagctta atatgataga aacaatagaa acgaaagaag aaactgaaat ctatttttca
    10021 gcttcttctt ttttattatt tattgttttc tgctaaaatc tgataaattc gtgtcacatc
    10081 agatggtgtt ccccgtaatt cataatctgc caagaaagga aagccaaatg tttgtgcata
    10141 ttgtttggct gttagacaat actgattatt gaagttttta tttccgctac cgactacacc
    10201 aagacaaagt ttatgattgt cttcatgttc cagatattca cgcatcgttt cggtcaagat
    10261 ttctgtatca ccgttatcta aaccatttcc gccgtctaaa taagtaggaa cgaaagtaaa
    10321 aaatggttct gtttctttcg taaaatcact attttcatgg atttctttta aagtaacttc
    10381 aggattgaca ggatcttctg catgcatttt ttcagcatat tctgctagat gtttggcaaa
    10441 ggcacgcgta tttcctgaaa tcgatatata taaaatgttc atggatcatc ctccaattct
    10501 ttccttttag tatagcatct tttttaagtt ttttggtggt gtaatttgga aagggactag
    10561 gcgctttgct tgtataatga gaaaaaagcc ggtagaatta tatttctatt aaagttttta
    10621 ttaattaagt aaaaataaaa aaggtttgtt atactttttg ataaaagcgg ttttattttg
    10681 gaggatgctt acatggatac agagcaacag aaaaaaggaa ttggtttaat tccacttgct
    10741 gccttagtaa ttggttcagc gattggaggt ggcgtatttg gtattatgac ggacatctcc
    10801 ggatcggctg gcggcccagc tattttcagt tgggtactcg taggaacagc aatgttgatg
    10861 ctctccttgt cgatcaataa tatcaataaa aaacgtccag atttaaaagg cgggatcttt
    10921 agttacgcag aagaaggttt tggccgtttc gctggtttta tcagcggttg gggttactgg
    10981 ctcacatgct ggttaggcaa cgtagctttt gcaacattgt tgatgagcgc attaggatat
    11041 ttcttcccag tatttgaagg tgggcaaaat ctggcatcga tcgtgatgag tacagtcttt
    11101 ttatggggat atgcatggct agtgaatcgg ggagtcgaaa atgctagttt cgtcaatgct
    11161 atcgtcacat tctgtaaatt agtgccatta tttttattta ttgtagtagc tatcagcacg
    11221 ttttcgatcc aacaattcat tgataacttt tctagcgaca ttatattgaa tgcgaatgga
    11281 cagccgatcc cgttttccag tcaagtattg agttgcatca tggtgatgct ttgggtattt
    11341 gttggtattg aaggagcctc tgtcgtaggt tcacgagcaa aaaaacaatc agatgttggg
    11401 aaagcaacga ttctagggat attcggcttg attattattt acgtcttggt ttccatgctt
    11461 ccatatggga caatgacgat gaatcagctg caaacgatca aggcgcagcc tgctatgggc
    11521 tatgtgtttg aaatgatggt tggtaaatgg ggagcagtcg tgatcaacgg cggtttgatc
    11581 atttctttag ttggtgtttg gctctcatgg acgatcttac cgattgaaac aatgggaaac
    11641 atggctgaag acggactttt gcctaaagca tggggaaaac tcaacaaaaa tggggcacca
    11701 acttatgcta tcgtattgac gacgttatgt acgaatgtct ttttactttc attattattc
    11761 actgacagtg cttataactt tgcttacaca cttggtacag cagctatttt cttcacgtgg
    11821 cttttcttag gattgtacca aatgaaactt tcttatcagc ggaaagaatg ggtccaattt
    11881 ttagtagggc ttttagcaag tgcctttcaa gtatgggcta tgctagtcgt agcctttaat
    11941 gaagtaatgc ttgttcttgt tcttttcttg ccaggcattt atttttacct caaagcacgt
    12001 aaggagcaaa acgagcctgt acaacatatc cacttagata agattttact tataggtgtg
    12061 acgatggtcg gagtgattgc aatggtttta tttgccactg ggatgcttca cgtatagaag
    12121 tataaaagaa gtataaagag aggttgtgag cctgtcgttt attcaaaaac atactaggaa
    12181 aggagctgtg acacaaatgt tgtcacagct cctttttcag aataaacggt gtttaagaga
    12241 cagccaatcg gcaataaggc tgaacgtctc tttcacagcc tcttttttga tgagtcatca
    12301 tacatttttt cgcttaaata cgagatatcc taatgctaag aacaaaacga tgtaagctaa
    12361 attaccgaat agcatttgat tagtagaaag atgagtcaat tgcttcatga tctcttcgtt
    12421 tccaatttgg ttttgcagat tcaacatact gatcggattc catttgatcc actcccattt
    12481 ttggatgagt gcaataagga taccagatat gattgacgaa gcaaaataaa agacgattcc
    12541 tgctgagatg gatgcgccgg aactattgat aaagcaagca atcatcaaca ctaaacttaa
    12601 aatcagccat aaaccgatat aactacccaa agtataagtg aacaagcttt ggatcagtgt
    12661 ttgaccagta gaaaccttct ccgtgaagga aatcgaaggg aaaagaatca gtttcatcaa
    12721 cacagtgaca ataatagcta aaaggtataa ataaacagaa taaataacta atgtgatcca
    12781 tttgcttact aatatttctc ctcgagaata ctttcgataa aggagatttt tcaatgtacc
    12841 atattgtgct tccatcgaaa tgatcgtgct tgcagctgca atcatgataa agacaatcca
    12901 agatgtggca ctaaaaagct gagcagtcat ttcaactgga tcaatgatcg tcgtgtattt
    12961 tttggctaga agtgctgttc ctatgagcaa aacaactaat agaacagata aaacagcagt
    13021 tgactttttc ttgatcaatt taaataattc ttgttttaca agcaatgtca tttttcttct
    13081 tcccccttta ctgaatccag aatttccaat agagaagatt ccaaatcatt cgtcagatgc
    13141 tggacgtctg tcacatggat attttgtgca gacaatagct ggatcacggt tcctaataat
    13201 tcttcgtttt cttttaaaag cttgatttta tcaggatctt ccaaagtata tccagcttct
    13261 gtcaagatcg ttcgagcagc tagatcattt gttgtagaga taacgatgaa atcttgcgct
    13321 gtttggttca attcagccat tgtacattgt ttgatgatct ttccttgatt gatcaggatc
    13381 agctcatcga ccattttttc aagctcgctg agtaagtgac tggagatcaa gaaagaggtg
    13441 ccctgagtag ccaagtcggt aatgattttt cgcacatctc ttgttgcttg tggatccaaa
    13501 ccgttcatcg gctcatctaa aataacgata gacggatggt tcagtaaggc aagagcaatt
    13561 cccaattttt gtttcattcc caacgagtag gatttcgctt ttttgtgaat gtacttttcc
    13621 atcttgagct gattcacgat agtgtcgata gcagatacat cgttggtttc agagaataac
    13681 ttcagatgat catagcctgt taagaatgga tagatacccg ggtattcgat caatgctcct
    13741 acttgttcca accctttatg actagaggga gaaatctcat tttcaccaat acagattgtt
    13801 ccatctgagt aatggatcag tcctaaaata gctttcatga tcgttgtttt tccagcgcca
    13861 ttaggaccta ctaatccaac gattttgcca ggggataagc taaaactgac atcgctgagg
    13921 gcttgtttgt gaccaaagtt cttggataat tcttggaccg aaagactttt caaaaatatt
    13981 cactcctttt ctatagatag tacaagcata cacctgatga gtggagaagt cgctaggtca
    14041 ttggacttat ttcttatttt ttcataaaaa aattgaatat taaataaaaa ggcttatttt
    14101 ttctgatcag tacttattcc aagtgtctag tggccgctag taatcttgat gccaatgata
    14161 ctgatgagta gcatccccac aaagaaccaa gtggaaagat tcagcttatc atgaaacaag
    14221 accacaccaa ttatgaccga accaactgcg ccaatccctg tccagatagg ataagagaga
    14281 ctcatcggca aacttttgat tgcctttgac aaaaagtaaa aactagcaat catgccaatc
    14341 actgtgtaaa aagaataatt gattttagaa aaaccatcac tccatttcat catcgttgac
    14401 cagaatactt ccaaaattcc tgctatgatt aattccatcc atgccatact tacattcctc
    14461 cttaactata aaaaaataca caaaaagagg aaaatcatcc cttcaaagac ctaatggaat
    14521 gatcatcctc tttatcctac ccggtggcag attgtatatc tttttctgta gtatagcaca
    14581 cctatccaga tatcggcaat ctcatacttt ttagtaaagt gtaccaagca ctgacggata
    14641 tatcgttagc ggaaaagaag atgaatgctt tgcaatttca tagaaagaag ttgttattta
    14701 ttaatcattt aaaaaaaaca gtaactagac cttatttcta tatattatcg g
//
LOCUS       DACGDM010000289        13213 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.074, whole genome shotgun sequence.
ACCESSION   DACGDM010000289 DACGDM010000000
VERSION     DACGDM010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.074"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(204..2162)
                     /locus_tag="IXR05_003079"
     CDS             complement(204..2162)
                     /locus_tag="IXR05_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4261489.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="IXR05_003080"
     CDS             complement(2159..3031)
                     /locus_tag="IXR05_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4261490.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="IXR05_003081"
     CDS             complement(3373..4245)
                     /locus_tag="IXR05_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4261491.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="IXR05_003082"
     CDS             4373..4942
                     /locus_tag="IXR05_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4261492.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="IXR05_003083"
     CDS             5009..5746
                     /locus_tag="IXR05_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4261493.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="IXR05_003084"
     CDS             5977..7245
                     /locus_tag="IXR05_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4261494.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="IXR05_003085"
     CDS             7732..8196
                     /locus_tag="IXR05_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4261495.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="IXR05_003086"
     CDS             8180..8809
                     /locus_tag="IXR05_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4261496.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr"
                     /locus_tag="IXR05_003087"
     CDS             9163..10641
                     /gene="msr"
                     /locus_tag="IXR05_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4261497.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="IXR05_003088"
     CDS             10688..11134
                     /locus_tag="IXR05_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4261498.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="IXR05_003089"
     CDS             complement(11333..11848)
                     /locus_tag="IXR05_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4261499.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="IXR05_003090"
     CDS             11965..13167
                     /locus_tag="IXR05_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4261500.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DACGDM010000290        13064 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.077, whole genome shotgun sequence.
ACCESSION   DACGDM010000290 DACGDM010000000
VERSION     DACGDM010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.077"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            3..500
                     /gene="dfrG"
                     /locus_tag="IXR05_003091"
     CDS             3..500
                     /gene="dfrG"
                     /locus_tag="IXR05_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAQ4261501.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(572..2524)
                     /locus_tag="IXR05_003092"
     CDS             complement(572..2524)
                     /locus_tag="IXR05_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAQ4261502.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2531..2827)
                     /locus_tag="IXR05_003093"
     CDS             complement(2531..2827)
                     /locus_tag="IXR05_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261503.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            complement(3002..3805)
                     /locus_tag="IXR05_003094"
     CDS             complement(3002..3805)
                     /locus_tag="IXR05_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4261504.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            complement(3821..3937)
                     /locus_tag="IXR05_003095"
     CDS             complement(3821..3937)
                     /locus_tag="IXR05_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAQ4261505.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(4182..5111)
                     /locus_tag="IXR05_003096"
     CDS             complement(4182..5111)
                     /locus_tag="IXR05_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4261506.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            complement(5128..6150)
                     /locus_tag="IXR05_003097"
     CDS             complement(5128..6150)
                     /locus_tag="IXR05_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4261507.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            complement(6147..8174)
                     /locus_tag="IXR05_003098"
     CDS             complement(6147..8174)
                     /locus_tag="IXR05_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261508.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            complement(8171..10624)
                     /locus_tag="IXR05_003099"
     CDS             complement(8171..10624)
                     /locus_tag="IXR05_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4261509.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            complement(10608..11003)
                     /locus_tag="IXR05_003100"
     CDS             complement(10608..11003)
                     /locus_tag="IXR05_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4261510.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            complement(11075..11713)
                     /locus_tag="IXR05_003101"
     CDS             complement(11075..11713)
                     /locus_tag="IXR05_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261511.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            complement(11769..12263)
                     /locus_tag="IXR05_003102"
     CDS             complement(11769..12263)
                     /locus_tag="IXR05_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4261512.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            complement(12330..>13064)
                     /locus_tag="IXR05_003103"
     CDS             complement(12330..>13064)
                     /locus_tag="IXR05_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAQ4261513.1"
                     /translation="LLIKTLERKSSSNYYEGGNEIVSKMKISEVTLDETDDFTYYKGY
                     KKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGDNVLVDTILVPLPENY
                     EVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHGYLIEILKKYEITVPR
                     DENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLNEARNRHSLAHPNTNI
                     IGKREAKLIIGISSTVTDYISGYLDK"
BASE COUNT         3865 a         2542 c         2153 g         4504 t
ORIGIN      
        1 aaatgaaagt ttctttgatt gctgcgatgg ataagaatag agtgattggc aaagagaatg
       61 acattccttg gaggattccc aaggactggg aatatgttaa aaatactaca aagggacatc
      121 cgataatatt aggtaggaag aaccttgaat caatcggaag agccttacct gacagaagaa
      181 atattattct gacgagagat aaggggttta cctttaatgg ttgtgaaatt gttcattcaa
      241 tagaagatgt ttttgagtta tgtaaaaacg aagaagaaat ttttattttc ggaggagaac
      301 agatttataa tttgtttttc ccttatgttg agaaaatgta catcacaaaa atacatcatg
      361 aattcgaagg agatactttt tttccagaag tgaattatga ggaatggaat gaggtatttg
      421 cccaaaaagg gataaagaat gataaaaatc cgtataacta ctattttcat gtatatgaaa
      481 gaaaaaactt attgagttaa cgggtgcgtt aattgaagaa gaacagtaaa gataaagcac
      541 aagagcttgg gattactcca agctcttttt gtcatttgaa ataaattata tctttccaat
      601 caaattgttt atctgtaatc cctaatcttt gagcaggtgt caaaaccttt ttatccgctg
      661 atttaaaagg gcgacaaaag ttgtagtaag ttcttagaat tgtaatcgca aattgagcat
      721 acttcggatt gaagttagcg taaatatagc tcttcttatc accacgagct gttgttaatg
      781 gtctttcaag agatgatata taacgtctta tctgttgaat aaagctattg gtcgaatggt
      841 cattaacatt taatagcatc tttgcgattt cgtttggttc cagagcagat aaatccgttc
      901 tacaatcaac tgaataaaat cctttatcct tagtggctaa tggatgtttg atagggttat
      961 cggcatattt gcgatatctt tctccatctt tactaatagc ctcttcgtgg aattgatgac
     1021 ttgttagtaa ttcagttaga taatgagatg ccaaagtccg tagaaacttt gttttgaatc
     1081 ctctgatatc tccccaatcg agcagttctg cttttgcttg tccgaattct tttaagcatt
     1141 gttttctgct tttcgtcttg ttaacttggc aaataaaatg atgtgcatcg ctcaacctta
     1201 attctttcgt gaatactcta taaaaggcgt ttctaataga gaagtcatca tcactaatca
     1261 ttcgccattc gtcggcatta accatttgtt taattaacca atagtgagca gttgtagtat
     1321 aaggagcatc aacatttaaa ccatcgacaa atctactcct attagtaatt ttccctaatt
     1381 cgtgaagata agcattccta ttttcgctat cgttagcgga tggttcttgt ggataataag
     1441 accaatctaa cctatcattt ttacgactaa aagtattgag atggtcttct ttgaattttc
     1501 ttgtatcttc atttaattca tccattgaaa tattccaatc ataggcaaca tcagaacgga
     1561 acacatatct tgataagacc tcagcagata caactatata cgtttgcata ttaaggtctt
     1621 caaaccccgt atatttcttt gaaccttgtc ctttcttacg gacgttattt aggtagtagt
     1681 gcatcttgtc cgtattaagc cacatctcgt taaatttctt tgtttgaagg ggttgtgtct
     1741 catatcgttc taaaaactcc aaacaacgcc tatacagcca ctccagctta tgatagtagg
     1801 ttccaactcc aattcctaaa atatcacaag tacgactgac tgaaaccctt ccaacaacca
     1861 tcttagcgaa cattggaaga atggtgttct tttgttggtg ataagtagtg gtttcttctc
     1921 tttttggtag aacattagtg aacttcttac acgccttaca ttgatagcgt tgagatttgc
     1981 ccctactttt cccccttttg taaaattgct tcggctcatt gaatggggtt gattcttctt
     2041 ccgagcagcc ttctttatga aattgataat ctggctcaac atcttggatg ctattgattt
     2101 ctataaggcg tttaatttct tcaacaacag accaattaga taaaggggtt actgtacagt
     2161 tttgcgatac acctctgcca ataggattgt cattgcagta cataccttta tgacctttat
     2221 ctttggaact accagtcatt ttatatcgac ttggtttccc ttttacatct ttgaatttgt
     2281 gctgttcttt cccaaaatta caacaaaacg gattgatgca gtaattatat tgaatgggat
     2341 attcagaacc gttccattta aaagacgttg gcaagaacaa cattttgtta taccttgttg
     2401 caaatcgttt tggagttaat aaatcatatt gtttagccct atcttttaat tcttcgtttg
     2461 aaatcggaat tttaacatct acaatttcat cttccttcgt ggctaatctt ttaagcttgg
     2521 tcattgtcta tcaacccact ctatctttga tacccatttt ttcaacaatc cgcttattac
     2581 ttcgcttgtt ggcaatccat tcaataaact tcttatcgtc taaaatgttc aataagaatt
     2641 catccactgc ttcgctttca gtacgctctg catattcagc gtattgctta actatcaccc
     2701 ttacttgctc tgatatttcc caatccacag acttagcgtt cttatttttt ggctcaagaa
     2761 attgcatagg aaaatgcacc cctttttgct tagtaaattg taaccatttt aacacaccaa
     2821 tttgcattcc tacaataatt atttcacgtt cgcattttta tatacatttt aacttacatt
     2881 ttgtggtgta aattaacaac aaacgttgat ttaacaataa aaaacgagta tcaaattcag
     2941 ttgcaatttg atactcattt aggtttacat tttcactttt tgtactccaa aactgaacta
     3001 cttaatatgc aagacgttgt cttttttttg tatattcaat tttgaaaaca tttccgcaaa
     3061 gttcagacgg acctcgatgt gttgatgaat aaaatttatt agtaataact tctataaggt
     3121 tatcaatccc tatattactt tttgcacttc catgataaag agggaacaga gaacaattct
     3181 gaaatcttat gctttcctct tgttcgagtt ccaatgcttc taatgattta ccggacatat
     3241 atttctctaa aaggtcatcg tttccctcta ttaccgtatc ccattgttca gattcggtaa
     3301 agttcgtcac acacatatta ggatacagtt ctaccttctg tttgattaca atttcggcag
     3361 aaagtttctc tttaatatcc tgataaaccg ttgataaatc aattccattt tggtcaatct
     3421 tattgataaa aaagattgtg ggaatcccca ttttcctaag tgcatgaaat aatatacgag
     3481 tttgtgcttg tacgccatct tttgcagaaa tcagtagaat tgccccatct aaaactgata
     3541 atgaacgata tacttctgct aagaaatcca tatgtcctgg cgtgtctatg atgttcacct
     3601 tcgtattttc ccactgaaaa gaggttattc ctgtctgaat tgtaattcct ctctgacgtt
     3661 ctaaaagcgt attatccgtc ctcgttgtac ctttgtccac gcttcctaat tctgtaatcg
     3721 ctccactgtt atataataag ctttctgtta aggtagtttt tcctgcatca acatgagcta
     3781 aaactccaat attaataatt ttcatgtgat tttcctccat tcaaaaaccc aaaagggcat
     3841 aaaaatccca gtgataaata cttttatcac tgggattttt atgcataacc ataggtatac
     3901 aaagcataca gatattctct ggatacttta gaatcacatg ataaaggtat tcttaaactg
     3961 ggtacaaaaa actaagccct cctaaaaaag gacatctaat tatttgttcc cgctatcaaa
     4021 ttgacagttt atttaagaat accttgccgc atatttatta actcctttta aatagtcact
     4081 taaataatag cacgtaagag catatttgta aaggaatctc caatttttta tcaaaaagag
     4141 tacatgatta caaagtatct gtaatcatgt accaatattt gttattttac aatcttccaa
     4201 ttatcttgtt tttctaatat caactcaaat tgcgagattt gggttgcctt tgtttcttga
     4261 tctaaatatt tcacagcgac attcacgatt acttggttat cttttctggt aaagatagga
     4321 ttcaccaatt cctcgaaaac atattccttg ttaatcatag gtaacacatg attacttaca
     4381 tagtaagtca attctttttc tgtggcggta ggatagagct ggaagaacgt ttctaaaaag
     4441 ctagtgattt cgtccatcgt ttctgtatct actgtatggt cactttctag ctgtttgggt
     4501 tggtagtccg atttttgagg tttcttactc attgtcggat ttttgataat aaccatatta
     4561 tctgattcat ctatatggac aaccacatga aagctagacg atatagtttc cttgtctttg
     4621 tcttcggtaa taacttgttc aacagaaaac agtacctcaa aggtgttctc attcacttga
     4681 gaaacctgcc acacctgtat atcgttcaca ctagaactag taggaatatc cttacgaatc
     4741 atttcttcat ttaatacctg caattcttcc gtcaaataat gggtcaattt ttcatttcgt
     4801 ttatcaatgg cttcttggga ttgttgccac gaaaagtagt ctttcgcaaa ggatttcaca
     4861 aaactttcta cttggttggt atcgacaatc tgctgtttaa tgatttctgt ttcacggaca
     4921 gtatgagtgt caatggcagt aaaattttta tagattccaa atccgacact accaatcaat
     4981 aaaacccata aaacaaaggt taatttctta tgcgtgccaa ctttaatcat cggaactttt
     5041 ctttgcttgc tcggtttttt agatttcttt ggtttctcct tcttttcttt tcgctcgatt
     5101 tttataatca tttgattcat tcctttctta gttatgaata acacgtctag ccccaatcag
     5161 atggtcttgc caataacgac tgcttaagtc gccataaccg attgggtcgc ctgcatgata
     5221 aaagcgattt ccctctaaat atatcgccac atgagtcaca tatgtgcctg cattataggt
     5281 tgaatgaaag aagataaggt cgcctgcttg ggcttcttcc atagagattt cttgcgtagc
     5341 gtcatactga tcttgggcga cacgagggag agaaatgcca gctttgtcat acacccattg
     5401 tattaagcca ctacaatcaa aagaggtggt aggcgacgcc cctccaaaga catagggaaa
     5461 cccttcgtat ttcaaggctt cgtccataat gacttgcacg gtttcatcat caaattctgt
     5521 tggggaagtg tcggttaggt attgtgaaac caactgaaca taaaactgat ttccatagtt
     5581 atatcgccaa ccaccattca caggtatggc tataggattg ggatagtctg ctttttgacc
     5641 acccgacttc tctttagaaa actgttcggc taattcatag gtatattttt tcccatgact
     5701 cctcacataa tttaaaaagc caccgccata attataagat tggataacag aatctatatc
     5761 cactccttgt tgttctgcac tggttaataa ttcactgaaa tatttaaccc cttgtttgat
     5821 ggactcttcg gtactcaaac tgttgggcgg taaacccaaa gattcggaac tttgcataac
     5881 atcttctgct gtaccgcccg attccacttg cataatggct aagatataag aaacatagtc
     5941 ttcaatccca tattccttac catatttttc aatcaacgga cggtgtgcca acacttctgg
     6001 tgaaacggtc acaccgcctt gtggaataga agaatccttg ttgttttcgc cactgtccgt
     6061 atcatctgca aagaaaatga ctaggaataa taagagaaaa aagaagagag agaagaccac
     6121 actacaaatc actgttattt ttagcttcat gtttgttgtc ctcgcttatc cgttctttta
     6181 tttagcttcc tctgattgaa ttgcttcggt ggtgtctttt gtttttgctc ttttttcaat
     6241 ggtcgctgat gattttcacg tttagtgttt tgtgacaaaa caggcgtgac ggtttgctga
     6301 cgcttgcgaa catgctgctg gttattctga acaggagatg atgggttttc ttttcgtctt
     6361 ttttcttttg ctttatccag ctccaaacgc ttttgagcaa tgttctttcg tttttgctcc
     6421 tgctggttca tacgctgttg tttgcgttga gctttggtat ctgccataga ttgtttaaag
     6481 tctgttacat tatgagtgac attctctttt ccttgatgaa gggcatattt gacatgggtt
     6541 ggtgtcgcct gtatctgttg ttttgcctgc tttcttttat tgactagacg atttttcgtg
     6601 tccaatacat gggctgtctt ttcacctaat cgttgcccga taccgccttg ttgctttttc
     6661 acattggaaa gtgctgtttc tttctttggt gtagtccgtt cattttgacg agtatggtta
     6721 gctttattgg tttgattctg ctttgttgtc attgtctttt gcttcgttga ccctgctttt
     6781 ccacgaaaaa tcttactcat actgcgttga aatcttctgg tttgtcgatt catcatttga
     6841 cgaggtctgc gaaacacttg tctgcccatg ttttgagagt cgttgctttg taaagtgaat
     6901 aggctcatta aatcgcccag tttaaaataa atccctgcaa aggtcacaat ttgtaaaaac
     6961 ataatcatga aaaagggaga acttgctgac agcgaataaa gcatagtgga aatactaaag
     7021 gcaacggtaa taatcaaggt aataccagcc cttgtcataa tcacattaaa taacttggta
     7081 atggcatgcc tgcccatgcc atcaaaactc ggcaacatac ttaataggaa actgattggc
     7141 aaaaacatag cgaaaataat aaatagcact tgcgaaaaaa tcatgattcc tgttagaagg
     7201 aaaacaaaaa tcgagatacc aatattgaat acaaacaaaa agaagactgt tcctaatctg
     7261 gaaatcgtct tcggtagggt taaataggta ttgtcatgat cttcaatttc ttcaatcact
     7321 acattttctc tatcttcacc attgtttgta tctggactgg tagacaataa actttccaca
     7381 cgttcttccc ctaacgcttc tacatcagtg gagccatatt gaagcaatag ccatggttgc
     7441 tttacttgaa cagagaataa gctgtcacgt atcatgtcca cactgtcttt cccttgacta
     7501 tccgtgttag gaagaacaat ttttgtccca atattcagac tggcggtact gacatctttg
     7561 gaaaaatcat tgattttcgc aatataatcg ggtgcatacg caataaagga agccgataga
     7621 ataaacacca cgacaaagtt taaaacagct cgtatcactt tcgtcgtttc tcgcttaacc
     7681 aatcctgtat aggcaacata gattccaaca atgagaataa aaagaaggag gaaaccgaca
     7741 taaaaccctg aactggaaaa gccattcggt gtaatgcctg caatcgtctg catgttttcg
     7801 ccaattgctt gggatgtttg actaatgaaa tctaaggcat aggcttcttt caccaaataa
     7861 cctgtggcgt tcgatagata aagagaaatt gtccaaataa aattagtaat ggcatacaat
     7921 ccatacatca ccgattgtcc tatgccatca ctccaattcc atggaagcca gccccagcta
     7981 ttgtccacat aataatcaag ctgatattga ttcaaaccat acttggagta ttcattgctt
     8041 gtatcaatgg tttcatcaac taagcctgtc gcttgtactg cattgcccag cgtgcctaat
     8101 aaaagtaaaa taacgcccac acaaaggagc gttatccaac tatagtgaag aaatttcttt
     8161 tgtttttgtg tcattcttcc acctcatttc gcacaggcgg tctggtatca aaggcatgaa
     8221 gcaactcttc aaaaatcggg tgaaactgca taacccctac acgaccatag atgtctgaaa
     8281 ctaaacattg tccattttct aattcacgta agcgtttctg attgttttca tcttccttgt
     8341 ccacaccaaa aaattctaag gtctttttga tttccactag gtcagtggaa cgaaaggcaa
     8401 atttcaagcc aatattattc ttcatctttt catctagtaa atcgtccgcg ttttgagtaa
     8461 cgaaatagac ccctgcattc atggcacgtc ctgctcgaac caatcgcata gatagagctt
     8521 ttccttgtgc cacttgtaaa aaactccaag cctcatcaag gtcaacaatt ttaaaaatgg
     8581 aacggtcaga gtggataaag tctaaagcaa aggtactaat gacaatcagc attgccacac
     8641 ttaataattc catggtagtg tattcttcaa aagagctatt ggaatcgggt aagaccaaat
     8701 ctgccacttg aataatattg agttgttttt ccaagctaat ggattgggtg acactgccat
     8761 cactgaataa cagatgggca aaatcataat cgacaaagct ttcgatatgg tcagcaatac
     8821 tattgctgat gggcgtatct tcttttcgca attcatcaat caccaataac aaccctcgtt
     8881 gtttgctttg agttacactc cgaatagctt tacgcaggac aggaaacttc tcgctatctc
     8941 ggctggaaat acctgttaag aacgtgagaa tatcaatggc aaggctttct gaatctttcg
     9001 ggagttttaa aatcacataa gggtcaagta accctttatt gtcgttctca ctcgtgagat
     9061 taacaatatt gatttcatgg gcaatatcag gtaaggtttc tttccattca ccacgttcag
     9121 cttttgggtc aacaatggtt gcctgtccgc caaagagtac tgaataatag accagcatat
     9181 tgttagagaa tgattttccg ccacctaatg aaccaataaa agcggacgct aatgcatttg
     9241 ttacagagcc tttaattcct tgacttgcaa ggctaggttg gagataaata tttctgcctg
     9301 tatcgagatt gtaaccgacg taaataccag aattttcacc aatcatttgt gtagcaccga
     9361 aaccaagacc agccaaaaaa tccgacgtga catattgaat atagtcattg atatatcgct
     9421 tgcttgaggg aataaattca ttatgcaagc ctagcatatc gccaaaaggt cgtactaatt
     9481 tgatagacag atcatcataa aaatctttta cttcatcaca acgttgtttc agctcgtcca
     9541 aattctttgc tgatacccgt accacatagc ttagtttgta catagattct ttggtttggt
     9601 ctaaattact ttctaattca tcgacagatt ctaaagcgtc caccacatta gtactggttt
     9661 cgttgtcgct ttcccatgcg tggctatcta aatctttcag ttctttcttt ttattgcgaa
     9721 cggtagataa ggctttttta ttggcgacaa tttcaacatt catactggta tcaacgggga
     9781 aagtaaactg ctgttgctgg taataaaaaa tttcactatt agggaaatcc aattcaccaa
     9841 caatactatt aattgtaaaa tacgccacat aagtagtggt atcttcctgt tcaatccgta
     9901 aatagcgttg attttcttcg attaaacagc gagtgggttt gagaatatcg tatttcttta
     9961 ccaacacttt tttatcttcg tatcgtttcg gtaaatggta gtcgtagtca tcaaaaggga
    10021 cacctgtttg cccgtaaaga tgttcaataa tataaccaaa atcatctttc tccaatttac
    10081 gaatctgaaa gcgtctggat aatttacttt ctaacaactg ttccatctta gaaaagcgtt
    10141 cgatttccgc cataggcata gaaacaaaat cgcccattaa tttgtgattc acaccatgaa
    10201 agaattccgc aaatgctttt tgaatttctt tcccaacatt ttttacggat acttcctgtt
    10261 cattgaggta gagtttaaaa ccaataaaaa agcgatagtc tacttgattg tcaccaatca
    10321 tagaaattaa cgcttcggtc tgttcatcta ttttttcgta agctatctct tttaatcgtc
    10381 cagtgatttc ttttttcgat tgttcctgtg tggctcgaat acttgattcg gttgctagtt
    10441 gcagagcatg aatcttgcca tcacgatttt gggcaatcaa ttgacagaaa ttatcatgaa
    10501 cttgaatttt ttcatcggaa cttaaaaaac tgtaattata gggaattaat tcataataag
    10561 cgaatacttc gccatcatga ttaaatacga gattatcttc catatattta atcggatatg
    10621 ccatctagtt gttcactcct tacaatcgta atcgattcat tcattgtttc tttttttaat
    10681 cgtatttgtt tgccagcgta ggttacttta gggcgtagag cataggtaat gatagacttt
    10741 agaaatccat agggtttctt tccgtcaaag gtcttttggc acatgaaccc agtgagaaca
    10801 atgggaatcc ctaagtattt gagtagtgct ccgtcaatca gagaaagtgg tggtaaactg
    10861 ccaaagagta tgacgacaaa caaagaaacg ataaaccatg tcatttgcgt aaaggtaatt
    10921 gggaaaggga gttgtaaatc attaatcgca taaatcactt tttctactga ccaaatactg
    10981 gtgtaacttc ttattttttt catgtcttca cgtcctttcc gtaaaaatag aaaaagaaca
    11041 atcaaaatag gtgattgctc tttcaatgct ttaactattc aattttattt tttgtccatt
    11101 ttgcaataat accttcatca gtttcttcat catctggatt cattgaatat ctgaaactta
    11161 aattggtatc tgaccctaat cgttcatata agctgggtct atacaatctc gttttattgt
    11221 cattaaaagg acttcgtttt cccagctcac catttccctt taaaggattt cttctaactg
    11281 aaaaacaata tttttttctg ggatcttctg aatcactttg acttaatgag aaacacatgg
    11341 cttctttttg gtcttcattt ttcttctcac taacttctgt cggaataaat cgagcaagag
    11401 tttggctaaa ttgaaataaa acatctccca agttactact gtattcgata ccaaaatatt
    11461 ctcttattgt tttcgtgtct gtatataatt ttaccgaatt agcatagaca gctagcatat
    11521 ctgaaaaatc gttttccttt aaaaattcta gttttaacag agcatattct ggaacttttt
    11581 cctctttttc aaatagctta acaagtacaa tataattttg ctgtttgtaa cgaaagtaaa
    11641 aggaatctat cacccagcct ttatctttca tgtctagttt taatagttta agattttcaa
    11701 atacatttac cataatttat acctctccgt gctatttatt aatttaatta taacacggat
    11761 tgttaaactt actgacaata ttcaaatacc ccatgagagg taactaggta attaccctct
    11821 atttccatat cacgtcccaa agattggtag tcaatataat tttgtaaatt ggaagggact
    11881 tcaccaagct gtcctgtttc ttccacgtaa taacgggcga catcttccat cgaatcacaa
    11941 tcactataac aatgaatatc ctctttgttt tccagtaatt cttccaagct actaaaccac
    12001 atgccttgaa tttctttgag ttcattataa ataggtgtac cttcgatttc ttgaatggct
    12061 tcacatagac ggttgatttc actaatcggc gtgtattcgt ccacatcaaa aggaagctca
    12121 aaatcatgta ttgcatattc ttcgtagtcc tcatttaaac cgattctttc tgccatttct
    12181 tcctcatcaa ttggtggagt aaaccatgct ccgactaatt caccttcatt ataccgtcct
    12241 aaatttgcca catagacttt catttccaat tcttatcaca tcctttttat aaaaatagtc
    12301 ataaaaaaag tagcaatcag ttaatgacgc tacttatcaa ggtatccgct aatataatct
    12361 gtaactgtac ttgaaatacc tattattagt tttgcttctc tctttccaat aatatttgta
    12421 ttagggtgtg caagtgaatg cctatttctt gcttcattaa gagagctaat cattccattt
    12481 gatgacctta tcgttgtctt cactatatca gcaagttcag taggttgaat ttctttttca
    12541 attaattgtt gtatcctact atataattta gatagatttt cgtctctagg aactgtaatt
    12601 tcatattttt ttagtatttc aattaaatat ccatgaaaag cagtgtgaac tctgtcaaag
    12661 gcacgttgat attcaccatt actcataaaa gactcagcgt cttcaatagc ttgtgaaacc
    12721 acatcactaa ttttcaactg actaaagtta attacttcgt aattctctgg aagtggtact
    12781 aaaatagtat ccactaatac attatcacct tgtttatcat atatggagct tgctgtctgg
    12841 gtaatcaaat ctttatgact ttcaaaaaag tctaaatcat caaaaggaac tcttatttta
    12901 agatatgtgc aaagcgtatt ccagcccttt ttatatcctt tataataagt aaaatcgtca
    12961 gtctcatcta aagttacctc tgatattttc attttagaaa caatctcgtt acctccttca
    13021 taataatttg aagagctctt tctttctaat gttttaatta aaag
//
LOCUS       DACGDM010000291        12695 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.081, whole genome shotgun sequence.
ACCESSION   DACGDM010000291 DACGDM010000000
VERSION     DACGDM010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.081"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            292..567
                     /locus_tag="IXR05_003104"
     CDS             292..567
                     /locus_tag="IXR05_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4261514.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            580..2652
                     /locus_tag="IXR05_003105"
     CDS             580..2652
                     /locus_tag="IXR05_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4261515.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            2817..4703
                     /locus_tag="IXR05_003106"
     CDS             2817..4703
                     /locus_tag="IXR05_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4261516.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4715..5662
                     /locus_tag="IXR05_003107"
     CDS             4715..5662
                     /locus_tag="IXR05_003107"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4261517.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5682..6209
                     /locus_tag="IXR05_003108"
     CDS             5682..6209
                     /locus_tag="IXR05_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4261518.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6272..6925)
                     /locus_tag="IXR05_003109"
     CDS             complement(6272..6925)
                     /locus_tag="IXR05_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4261519.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7057..7899
                     /locus_tag="IXR05_003110"
     CDS             7057..7899
                     /locus_tag="IXR05_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4261520.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8057..8953
                     /locus_tag="IXR05_003111"
     CDS             8057..8953
                     /locus_tag="IXR05_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4261521.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8956..9669
                     /locus_tag="IXR05_003112"
     CDS             8956..9669
                     /locus_tag="IXR05_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4261522.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9689..10207
                     /gene="msrA"
                     /locus_tag="IXR05_003113"
     CDS             9689..10207
                     /gene="msrA"
                     /locus_tag="IXR05_003113"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4261523.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10204..10431
                     /locus_tag="IXR05_003114"
     CDS             10204..10431
                     /locus_tag="IXR05_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4261524.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10583..11134
                     /gene="lepB"
                     /locus_tag="IXR05_003115"
     CDS             10583..11134
                     /gene="lepB"
                     /locus_tag="IXR05_003115"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4261525.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11217..11759)
                     /locus_tag="IXR05_003116"
     CDS             complement(11217..11759)
                     /locus_tag="IXR05_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4261526.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(11996..12394)
                     /locus_tag="IXR05_003117"
     CDS             complement(11996..12394)
                     /locus_tag="IXR05_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4261527.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12591..>12695
                     /gene="rbgA"
                     /locus_tag="IXR05_003118"
                     /gene_synonym="ylqF"
     CDS             12591..>12695
                     /gene="rbgA"
                     /locus_tag="IXR05_003118"
                     /gene_synonym="ylqF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264726.1"
                     /note="essential GTPase; functions in ribosome assembly;
                     binds a unique part of the 23S rRNA; interacts with
                     ribosomal protein L25(Ctc); Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAQ4261528.1"
                     /translation="MKKKKTSKAGEYSGMKGMERTMTIQWFPGHMAKAR"
BASE COUNT         4429 a         2160 c         2539 g         3567 t
ORIGIN      
        1 ttctgattca tcagtcccat aaattataga gccgattttt gtcgcagccc catttttttg
       61 ttgtgataaa agaacaagaa aggcaggaat gggaaagtaa acatcctttt gtcagaaact
      121 tttatctttc ttaagtttta cttgatatct gatactattt ggaatagaat gaggcgttga
      181 aaaatttatg gaaatttcta actagcaata aacgatgaaa caatgaaata tttttcatcc
      241 aaaaagaact ttgctataat gatggaagtt tgtgtatagg agatctggaa aatgagagag
      301 agttttgaac aacaaaaaaa actgttgcat gatcgctatg gcgccctttc gatggatgac
      361 cgccgtcaaa tactttgtaa gttgcgtaaa agaaatatat tgatgtatcg tcagttggaa
      421 cgtctgaaac atgatctgct tcgtttggag tcaaaacgtg tacagtgtga attagagggg
      481 aaccaaacac aggttgaagt agtcgaaacc aaaattttaa agaaaaaaga acaattttta
      541 aaaatgctta cacaaaataa aaaataaagg ggatggacga tggaatttgc tgagttagtt
      601 attgtatttg cagtaacgat caccttatcg aacatagcta gccgcatttt gccaatgatt
      661 ccagctccac tgatccaaat tttccttgga gtggtattag gtctgacaga gtggggacaa
      721 tcaatcgatt ttgaacctga attgttctta gttatgatta ttgcaccatt gttatttaga
      781 gaaggagaaa aagcagatat ttcttcgatt ctcaaaaatt tcgggacaat tttgttcttg
      841 gcatttggag gagtcatttt gacccttgtc ggggtaggtg cgacgttatc attcctgttg
      901 ccaagtgtcc cacttgctgc ctgctttgct tttggagcag cgttaggtcc gacagatgcg
      961 gtagcagtca gttctctttc tggacgagtg aatatcccta aaaaggcgat gcatattttg
     1021 gaaggagaag gtcttttgaa tgatgcatct ggtgttactg ccttccagtt tgctcttggt
     1081 gcgctgatca ccggatcttt ttcagcagta aacgcgggga tgagtctagt agtttctagt
     1141 attgggggag ctttgatcgg ctttttgctt gtctggttca aacaaaaaat aattcatttg
     1201 atcgaaaaag catcagcaca agatgtcaca gggtatctgc tgatcgaact tttgcttcct
     1261 tttctagcct atgtattggc agaggcattt gatgtatctg gaatcattgc tgcagtggca
     1321 gcaggtattc tccaagcttc tggttttagg aaaatctctg tgtttgatgc agaattgtcg
     1381 agcttgtccc acagtacatg gacaactatt gcttttacac tgaatgcatt agtatttata
     1441 tttttaggaa tcgaattgac gcaagtgttc tcgccagtat ggggagacgg tttatatcca
     1501 aacggtcttt tattagcgat tatcgtatta atctctgtca tgctttttgt gatcagattc
     1561 atttctatca gtctttttta tgtattcaaa gatggcagta aaaagttcaa aaaacagttg
     1621 aacgagatct tgatcttaac atttggcggt gtaaagggaa cagtcagttt ggctacgatt
     1681 tttattttgc cattttcaat caataatatg atgttttacc agcggtcttt gcttttgttt
     1741 ctgacggcgg gtgtcatctt agtgactttg gtcataggga tcattgtctt gcctatgctg
     1801 acggaaacag aggaagcgaa aagcacggat ttgaatgctt tgatgatttt agaagaggtc
     1861 gttgaagttt tgcgaaaaga aataaaggaa attgatcgta atacaaaaga atttttagcc
     1921 actgaagcag tgatagaaaa ttatcaagaa cggatacgtg atctgtactt ggaagattta
     1981 accgatgatg aaaagcaaga agtacaagaa atacaagcac tgattttgtc gatcgaacgg
     2041 gatggattgg atgaaagtta tcgttcgggc aagctttctt ctaatggtta tcgtttttac
     2101 tcccgttttc tttctcgatt cgaacattct atcacaagcc agattttgtc ttttatcggc
     2161 ttttggttca ttgttgtccg taggttaatg cgaatcgttc tccatccgaa aatgttttgg
     2221 caaagaagat atgctgatcg tcagacattt attagtgatg aagatatcca agaaatcaga
     2281 gagacatatc aaaaaaatac tcagttgatt attgaaagtt tagataactt gactgatatt
     2341 tatgatgaaa cgatggttca attttttatc cagcaacgca aacttgaagg aataaaaatg
     2401 aactcgggga atttgatttc ttcgtggatg atccagcaag atagtctgtt tacgaaaaaa
     2461 atgctaagag gttattatct tgaaagaaaa atcattgatg aatacgaagt tgctgaaaaa
     2521 atcacgacgt tttctgcgaa cagctatcgc aggaatatca atttgttaga atcttatacg
     2581 atgaacaaac catctgataa cttttctttc cgatttgcgt ttcgagcaaa gtcaaaaaaa
     2641 cgagtccaat aaaataaaaa ggtaaaaatt ttcaagtttt ataaaaaaca aaacatatca
     2701 gaacaggatc gaatcggtcc tgttcttttt ttgagaacac aaaaagaaca aataccaaaa
     2761 aaattttcct gaagttcact atttttatga tacaatatcc aagataagga gggaacatgt
     2821 tgaaagaatt aaaagtaact gacctcaaaa aaacttatgg tgaaaaagat ttgtttgacc
     2881 agatttcttt tttggtccac gaaaaagacc gtatcgggtt gattgggacg aacgggacgg
     2941 gtaaaacaag tctcttaaat attattgccg gtatcgatag cagcgacggt gatcggcaaa
     3001 cagtgtttta tccaactgat taccgtattg gttatctttc tcaagcagct gaattttccg
     3061 atgaattaac tgttctccaa gcagtctttc aaggaaacag ccccttgatc caaactgttc
     3121 gagcatatga ggaagcattg atcgaactag gggaaaacgg agaagaccct gatgtgcaaa
     3181 aacgttatgc taaagcagaa gaacaaatga ataaagaaga tgcttggact acagatacca
     3241 acgcaaagat tattttgcaa aaattaggaa tcagtgaatt agataaaaaa atcagtactt
     3301 tatcaggtgg tcagaaaaaa cgagttagtc tggcgcaagt gttgattgat gaacccgatt
     3361 tactattact agacgaacca acaaaccatt tagattatga agcgatcgag tggttggaaa
     3421 actatttgaa acaataccgt ggcgcactat tgatggttac ccacgatcgt tattttctag
     3481 atagagtagc aaaccgaatc ttcgaacttt catttggaaa attatacgag tataaaggaa
     3541 attatgaagc ttacgtctta gaaaaagcag aacgtgatcg tgtagaagta gaacaagaag
     3601 aaaagcgcaa gcggctttat aaacaggaat tagcttggat gagggctggc gtacaggcac
     3661 gtggcaccaa gcagcaagca cggatcaacc gtttcgaaga tctaaaggag aacttgtacc
     3721 aagtaaacca agaagatgat ttagagctga acctagcgac acaacgttta gggaaaaaag
     3781 tactggaaat caaagatggc agttaccgta taaatgacca aacactgcta gaacatttag
     3841 atttattgat tcaatctcgg gaaagactag gtattactgg taaaaatggt gcgggaaaat
     3901 cgacattgct taatattcta gctggcagaa ttcccctgga tagcggtaca atgtctatcg
     3961 gtgaaacggt tcatcttgcg tattatacac aagaaaatga agaaatggca ccagataaac
     4021 ggatgattgc ttacttacaa gaagctgctg aagaagcaaa aacagcagat ggcagtcaaa
     4081 tcggagtagc agaattactt gaacgatttt tatttccaag atttatgcat gggacactga
     4141 taggcaaact ttcaggcgga gaaaaacgcc ggttattttt gttgaaactg ctgattcagc
     4201 aacctaatgt tttattattg gatgaaccga ccaatgattt ggacatagca acattgacga
     4261 ttttggaaga ttattttaga agttttccag gtgctgtgat cactgtttcc catgaccgtt
     4321 atttcttgga caaggtagca gataagttat tagtattcca aggaaacgga aaacaagaac
     4381 tttattacgg aaacatgtcc agttatttac tgaagcaaaa agagacccag cagcctgctg
     4441 aaaaagcgaa accaaaaata cagagcaagg aacctgctga aaagaagaaa ttatcttaca
     4501 tggaacaaaa agaatgggaa acgattgaag atgagattgc agaacttgaa gaaaaaatct
     4561 cattgctcca agaagagatg aatcatcaag gagataattt cactcgatta caagaattgc
     4621 aaaacgacgt atctgaaaca gaagcacaac ttgaagaaaa aatggcacgg tgggaatact
     4681 tgagtgaatg ggtagaagat taggaggaaa aaggatggaa caagcgtatc ttgacttagg
     4741 aagaaaattg ttggaagaag ggcatcgtaa agaagacaga acaggcacag gcacattaag
     4801 cttattcgga taccaaatgc ggtttgatct gcaaaaaggg tttcctttgt taacaacgaa
     4861 acgagtacct tttggattga tcaaaagcga attgctttgg tttttaaaag gagatacgaa
     4921 tatccgctat ctattacaaa ataaaaacca tatttgggat gaatgggcat ttgaacgcta
     4981 catcaaaagt ccagactata atggaccaga tatgactgat tttggccata gatgtttgac
     5041 agatcctgaa ttcaatgaag aatataaaaa gcagagcaag cttttttgcg agaagatcct
     5101 aaccgatgat tcctttgctg aaacatacgg cgatcttgga cacatctacg gctatcaatg
     5161 gcgtcactgg gaaacaaaag acggtggctt tatcgatcaa atcaaacaag tgatcgaagc
     5221 aatcaaaaag actcctgatt ctagaagatt gatcgtttct gcatggaatc cggaagatgt
     5281 tcctagcatg gctttgcctc cttgtcatac gatgtttcaa ttttatgttc aagagggacg
     5341 gctaagctgc caattgtatc aacgcagtgg ggatgtgttt ctaggcgttc cgttcaacat
     5401 tgcaagttat gcgttgctga ctcacctaat tgcacatgaa acaggtttag cggttggcga
     5461 atttgttcac acattaggag atgctcatct ttatatcaat catatcgaac aaatgaaaga
     5521 acaattgagc cgagaaatac gcgcatttcc gactttagtt ttgaatcagg aaaagcagtc
     5581 agtatttgat tttgagatgg aagatatcca attagaagga tatgacccac atccggcgat
     5641 caaagctcct atcgctgttt agaatcagaa aggatgagaa aatgttagct gcaatttggg
     5701 cacaggatga aaacggattg attggaaaag aagaccgtct tccttggcgt ttgccaaatg
     5761 atctgaaatt cttcaaacaa atgacagaag caaatacact agtgatggga cgaaaaacat
     5821 tcgaagggat gggtagccgt ccgttgccga atcgtcagac gattgttttg acgagagatt
     5881 cttcctataa agcagaaggc gtgcatgtca tgcatagtgt ggaagacgtg cttgctctgg
     5941 aaaaagaaac agacggtatc tttttcatcg ctggagggtc agctgtttat caagaatttc
     6001 tgccattttg tacgatatta taccgtacag tcatccatca tgtattcgat ggagatgctt
     6061 attttccacc tgttgactgg tctgattggt cactgatcaa tactagtcaa ggagaaatgg
     6121 atgaaaaaaa tcgttatccg catcaatttg aaacgtatca gcgtaatgag aatcctgtaa
     6181 aaagcgggac aggcgaattg acgatataaa aaagctatgg atagactagc tgttatttag
     6241 agctgtccca tccatagctt tatttttttt attaagtaaa gaataaaaca gagaagtaca
     6301 taaaacctgc acctaacata acaaacaaat gccaaacaac atgcatatag cggatagaat
     6361 tcaagctata aaagaatgcg cctatcgtgt aagaaagccc gcctgctacc atcaaaataa
     6421 caccagtcat tccaagagag tgataaagag gaacagcagc cacgacacag agccacccca
     6481 taaaaatata gatgatcgta gatacttttg atactctctc ccgtttatgc aacgtcaacg
     6541 ctttatatat aatgccaaga atcgcaaaca accagattaa tacaaataaa gtccaaccta
     6601 gccatcctcg gatactcagc aaacaaaaag gagtataact tcctgcaatc aaaagaaaaa
     6661 tcgaactatg atcgaatact tggaacacct tttttgcttt tgtaaaaatc aatgaatgaa
     6721 acaaagtaga cgttaaaaat aaaagaatca tcatcgatcc atagatagca taagagacaa
     6781 tatggaggga ggaatgcaag tgggcacctt ttactaaaag aaccactagt cccgcgatac
     6841 tcaatccagt cccaattcca tgggtgactg cattaaacac ttcatttaat atttcatacg
     6901 ttcgattaaa tttcgttttt tccatgaaaa cggctccttt actaggtgta attaatgaaa
     6961 aatcattatt tgtctgttat actaaaaata gaaattgtct tacatgtagt ttaacatgaa
     7021 taaggcatct tgttaaagaa agagagagag aaaataatga caaatgtaaa aatcgtaaca
     7081 gattcttcat gtacgatgga aaaaaatgta cgcgatgctt taggcattcg tgtcatgccg
     7141 ctatccatca tgatcgacgg aacagtatat cccgatgatg accaactaga cggcgaaaga
     7201 tttatggaaa tgatggcgaa agcaaaaaat ctgcccaaaa caagccaacc accaattgga
     7261 gaattcatct cgatgtatga tgagctagga gaagacggca gtgaagtgat ttcgatccat
     7321 atgacaaaag gcttgagtgg aacagtagaa gcagcaagac aagccagtaa tctaacaaaa
     7381 acgaaagtaa cggttatcga cagtgatacc actgaccaag gattatcttt tcaggtaatt
     7441 cgagcagctg aattagcaaa agaaggtaaa acagtagaga aaatccttga agaagtcaaa
     7501 aaagtacaag acaatacaaa attatacatc ggaatatcca cactagataa cttggtaaaa
     7561 ggtggaagaa tcagccgaac aactggtttg ctgtctagtg ttttgaacat acgcgtggtg
     7621 atgaatttcg cccattctga attaatccct gtaactaagg ggcgaggaaa gaaaacgttc
     7681 gataaatggt ttaataattt gaaaaatgaa ctgaaagaat tgccaaatgt gcgacaaatc
     7741 ggtatttcac atgcggatgc aaaagaattg gcgcaagaat tcaaagaggg tttgcaagaa
     7801 ttattcccgg acatgcatat ccctgtactg catacgaatc cggttatcgc tacgcatact
     7861 ggtaaagacg cgtttgcaat catgtattat gtagattagt cgaaaagagg ataagccctc
     7921 agcctgaaag gcttgcagct tattctcttt ttctttataa aattaggaaa ataattgttt
     7981 tcttttttca taaagactac ctttttgata aaatttttga taacattaga accaatcgaa
     8041 tacaagaggt gaaaaaatga aattaacgaa acgacatttg atcctcgttt tgttcccatt
     8101 attaattgcg atcatcatct atgcaggttt agctgcttct ataccgaaag ctggcccact
     8161 aatgaaacca gtaactactg tgagagaaga tccaaataaa aaagaaaaac ttcactacat
     8221 agctatcgga gattcgctga ctgaaggagt aggagatcaa accaagcaag gaggattcgt
     8281 tccccttgtc gcaaatgatc taaaagaccg ttataatttg accgcggttg aaacagaaaa
     8341 ctatggtgta aatggtgaac gaagtgacca gatcttaaag cgagtaaaaa caaaagaaga
     8401 aattcgaaac aatatcaaaa cagctgattt tatcacactg actgttggcg gtaatgattt
     8461 gatgaaagtt atccaaaata atttattcgg gttaacggtc aattccttta aaaagccact
     8521 gaaaaactat caggaaaatg tcacagaact attggaagaa tttcgatccc tcaataaaac
     8581 cgcacctatt tacattttag gcatctacaa tccattttat ttgaactttc ctgagatcac
     8641 tgacatgcag acaattgtta acaattggaa caaaggaaca gaaacggtga caaaaaaaat
     8701 gccgaactgc tactttatcc caatcaatga tttgctttat caaggattga atcaggaagt
     8761 aggtgtcaca gaagaaggaa cagatcaaac aactagcacg acagaaaatc taaatggcat
     8821 caaaaataat gtgctctatg aagaagatca tttccatcca aataatttag gttatcaatt
     8881 gatggcaaat gcagtgagag atcagctgat cgagacacaa aaccaatggt tagagaagga
     8941 ggatgatcaa taaacatgaa aacaagatct gacgtatctt caaacaaaac aaagaaaaca
     9001 aattactgga aattcgcctt ccttatcctt cttggggtag tacttggttc gaccgtattt
     9061 ttaggcagcc gtatttttgc taatcgggaa ccagaactcc cagaaatacc agctcttacg
     9121 gaaagacaag gagatcctgt cttaacgatc aattcaaata aagaaaaagt caatcaaatc
     9181 atcagctttt tccttagtga gtatcaaaaa gatagtgata ttgaatataa attttatttg
     9241 gaaaatgaag cactactcaa tggtactttc gaagtactag gttttcctat cgatttctat
     9301 ttatattttg atccgtatgt gatggaaaac ggaaatgtcc aactaaaagc tagaagtctt
     9361 tctatcggaa cattgagttt gccaatcaaa gatgtgatga atatgatcaa gagaaactat
     9421 aaattaccag attggatcga agtcaataca gatgatctga ctatcatgct taggttggat
     9481 caattccgaa tgcaaaacgg gatgtatatt aaagcagata aaatcgactt agtaaatgat
     9541 gacattcggt ttagtctata tttgccaaaa gatacctctg atgcttcaaa caactcaaat
     9601 accaacaaaa ctagcaccag cagtactgaa agcaagacaa aagaaaataa aaaatcatcg
     9661 gatgagtagt attagagggg gaatcataat ggaacgagca atatttgcag gaggctgctt
     9721 ctggtgtatg atccagcctt tcgacacgct tcctggtatc catacagtga tgtcaggata
     9781 tactggaggg catgtaccag atccgactta tgaacaagta aaaagccaaa cgactggaca
     9841 tacagaagca gtggagatta tctatgatcc aacattgatt tcatatgaac aattagtaga
     9901 actttactgg cagcaaactg atccaactga cgctttcgga caattcgagg atcgcggtga
     9961 caattatcgc ccggtgatct tttatttgac agaagaacag cggatcattg ctgaaaaaag
    10021 taagaaacag ttagctgaaa gtggacgttt cgaacagcca atcgttacaa aaatcgaacc
    10081 agcccaacca ttttatctag cagaagaaga ccatcaagag tattataaaa agcatcctga
    10141 aaattttaaa agaaaccatg cacgccgggc tgcctttatc gaagaaaatt ggaggaacga
    10201 agggtgaatc gaagcttttt tcattattta atgacactgc gaggcggtgg cacacatgat
    10261 gctttatctg ttttcgctac agaagccggt aaagacatcc aatttcctaa gcacagctct
    10321 agctacgaag aaatttctaa ttatctggaa ctgaatgtcg actatttgcc gtccatggat
    10381 atctttgacg aagcatggga aaaatattta gaaaataatc atgacatata agagatagtt
    10441 ttgtacttta tgatcaaaaa agttttttgt ccaatagcct aattgaaaga attattttta
    10501 tttcagctat ctagtcgcat ttttttgata tttttcttat aataaagaaa gaatgaaaaa
    10561 aagagggatg gattgataga gattgacaaa aaaacaacgc tatattaatc gcttctggct
    10621 tgtattcaaa tacttacttg tttctgtatt ccttgcgttc atgttgcggg gatttttatt
    10681 catcccggta ccagtggaag gcaattcaat ggaaaacgtg ttgaagcaag gtgatatggt
    10741 tgtgatggaa aaattttcgg agatcagacg atttgatatt gttgtttttc aattagcaga
    10801 tggcacgatt tatatcaaac gagtaatcgg tcttccagga gaaaatgtca gctaccaaaa
    10861 tgatcaattg aagatcaatg ggaaagtagt taaggaacct tatctaacta aaaacctgaa
    10921 atcagatcat gcaaatgcat cctatacgac ggactttaca ctacaagagc taacgggaca
    10981 atccaagctt ccggaagata attattttgt acttggagat aatcgaagag tttcaaaaga
    11041 tagtcgttcg tttggcacga tcaataaaac tgatattcta ggtaaagcaa gatttgtcta
    11101 ttatccactt gatgaaataa aatggatcca gtgagaaaca ataaagcgtg cagtctgttg
    11161 agactgcacg ctttattgtt taatccaaaa tcagtttact accttagtac gtaaaatcaa
    11221 acagctcgtt taaacacttt tctagcctct aaagttttga taaatgaata aacaaccatt
    11281 atttgaatag ggatttggat catattcctg atgaatctac ctagaaaaat tactttgaaa
    11341 tctgcaccaa acaaaacaga catcagccaa gaattgataa aaaggctgac tgggatcata
    11401 atcaataatt gggcagcgat gacggaaggc aggtttatct ttttatgata taaaaataag
    11461 ccattaataa atccaccaag gaaagccgtg ataagaaaag cagcttgaaa cgttcctgaa
    11521 ccaaatatcg tgaaatttaa agtgttcgac aacatttcaa gcaaaccagc ccagatcggt
    11581 ccatatagat aacccataag cgccatactt aaaaatccga atgtgatttg aaaataagca
    11641 ggaccaatcg ctatcttgta taagatgaca tcaagggcta ataaaagagc agaggtcgac
    11701 aacaatcttg cattcatttc gggcaatcta aaaacgtctt ttgcaatcaa agtgttcaaa
    11761 atattctctc ctttgtcagt taataataaa aggataccat aaaatcacca atgtgtcatg
    11821 acacattggt gatttacata cactggcatc taacaattaa aaaaagggtg agaagactgc
    11881 ttttataaac tgtaaaaaag agattgtacg aataaaaaaa atagaggcgg agaatactta
    11941 tcgtatcatc cgcctttgtt tttttgttat aaaaaacgtc agattagtta tctgcttaca
    12001 tcttcatcca tacgggttct aatgtatttc cgtctagatc ttggacttct aatgaaaaca
    12061 tttcttcttc aggcattccc atatctactt cgtggaaagt accaccattt tcttttgcaa
    12121 tttgagcaaa tttttttact tcatccgcgt tttcaacact aaacgaaatc aaagcaccac
    12181 ttgttttttt attatcagct atttctttat cttttataaa ttttttataa aaatcatgag
    12241 agagaagcat tatccaaaaa gtgtcatccc ataccattga accagcttct tcagtagaaa
    12301 attcttcatt ttttttaaaa cccagctttt cataaaaagc aacggaacga ttgacatcag
    12361 caacaggaaa attaacaaaa accatactat tcatttgttt cgtctccttt ctgttttgtt
    12421 cgtctatcat ctcttattta ggaaacgctg tcaaaaattt agattcatat atagaaacca
    12481 aaataaaaat ttgcatcatc aaaaaagtga agatgtgata gaatgaggac tggttcactt
    12541 tcacttaact aatagatgga atttctttat aataaaaaag tgaatttata ttgaaaaaga
    12601 aaaaaacaag taaagccggg gaatattccg gtatgaaagg aatggagaga acaatgacca
    12661 tccaatggtt tccgggacat atggcaaaag cccga
//
LOCUS       DACGDM010000292        11374 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.088, whole genome shotgun sequence.
ACCESSION   DACGDM010000292 DACGDM010000000
VERSION     DACGDM010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.088"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            400..1440
                     /locus_tag="IXR05_003119"
     CDS             400..1440
                     /locus_tag="IXR05_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4261529.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            1538..1726
                     /locus_tag="IXR05_003120"
     CDS             1538..1726
                     /locus_tag="IXR05_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4261530.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(1784..2137)
                     /locus_tag="IXR05_003121"
     CDS             complement(1784..2137)
                     /locus_tag="IXR05_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4261531.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            2668..3090
                     /locus_tag="IXR05_003122"
     CDS             2668..3090
                     /locus_tag="IXR05_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4261532.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            3087..3317
                     /locus_tag="IXR05_003123"
     CDS             3087..3317
                     /locus_tag="IXR05_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4261533.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            3815..4015
                     /locus_tag="IXR05_003124"
     CDS             3815..4015
                     /locus_tag="IXR05_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4261534.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            4042..5235
                     /locus_tag="IXR05_003125"
     CDS             4042..5235
                     /locus_tag="IXR05_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4261535.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(5303..6868)
                     /gene="guaA"
                     /locus_tag="IXR05_003126"
     CDS             complement(5303..6868)
                     /gene="guaA"
                     /locus_tag="IXR05_003126"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAQ4261536.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(6927..7850)
                     /locus_tag="IXR05_003127"
     CDS             complement(6927..7850)
                     /locus_tag="IXR05_003127"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAQ4261537.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            8046..8651
                     /locus_tag="IXR05_003128"
     CDS             8046..8651
                     /locus_tag="IXR05_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4261538.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            8959..9975
                     /locus_tag="IXR05_003129"
     CDS             8959..9975
                     /locus_tag="IXR05_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4261539.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            10116..>11374
                     /locus_tag="IXR05_003130"
     CDS             10116..>11374
                     /locus_tag="IXR05_003130"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAQ4261540.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGES"
BASE COUNT         3723 a         2027 c         2239 g         3385 t
ORIGIN      
        1 ctattcttat ccatcgcagc aatcaaagaa actttcattt ataacacagc ctttttaact
       61 aatttaccat ctaatttctt atttctatca aaaaaccttt tctcattatc ctgcccgtta
      121 gttgaataag caattttttc tataagttat attatcataa taccacaaaa tcacaaattt
      181 tcattcaatt atcattttca attgcatttt ataaatcatt ttgtatgtaa tttggtatgt
      241 aagttaaaat gaaaaaagta gtccattttg aagtacattt tgtcattttg tactccaaaa
      301 ctgaactact tacttgcata tatacgcctt tatagtggag tactacattt acgagattcg
      361 gttagagtat cagaaaaaga aaaaataaaa gttacagaaa tgtatacttc aataaatggt
      421 gaattatgta agattgatag agcttattct ggagaaattg ttattttgca aaatgagttt
      481 ttgaagttaa atagtgttct tggagataca aaactattgc cacagagaaa aaagattgaa
      541 aatccgcacc ctctactaca aacaactgtt gaaccgagta aacctgaaca gagagaaatg
      601 ttgcttgatg cccttttgga aatctcagat agtgatccgc ttctacgata ttacgtggat
      661 tctacgacac atgaaattat actttctttc ttagggaaag tacaaatgga agtgattagt
      721 gcactgttgc aagaaaagta tcatgtggag atagaactaa aagagcctac agtcatttat
      781 atggagagac cgttaaaaaa tgcagaatat accattcaca tcgaagtgcc gccaaatcct
      841 ttctgggctt ccattggttt atctgtatca ccgcttccgt tgggaagtgg aatgcagtat
      901 gagagctcgg tttctcttgg atacttaaat caatcatttc aaaatgcagt tatggaaggg
      961 atacgctatg gttgcgaaca aggattatat ggttggaatg tgacggattg taaaatctgt
     1021 tttaagtacg gtttatacta tagccctgtt agtactccag cagattttcg gatgcttact
     1081 cctattgtac tggagcaagc ctttagaaaa gctggaacag aattgttaga gccatatctt
     1141 agttttaaag tttatgcacc acaggaatat ctttcacggg catataacga tgctcccaaa
     1201 tattgtgcaa atatcgtaaa tactcaactg aaaaataatg aggtcattat tattggagaa
     1261 attcctgctc gatgtattca agattatcgc aatgatttaa ctttttttac aaatgggctt
     1321 agtgtttgtt tagcagagct aaaaggatat caggttacca ctggcgaacc tgtttgccag
     1381 acccgtcgtc taaatagtcg gatagataaa gtaagatata tgttcaataa aataacttag
     1441 tgcgttttat gttgttatat aaatatggtt tcttattaaa taagatgaaa tattctttaa
     1501 tatagatttg aattaaagtg gaaaggagga gattgttatt ataaactaca agtggatatt
     1561 gtgtcctatt tgtggaaata aaacaagact acgaatacga gtggatacta tacttaaaaa
     1621 tttcccttta tactgcccca aatgtaagaa cgaaacttta attaatgttc aaaaaatgaa
     1681 tataataaca atcaaagagc cagacgccaa gacgcagagc cgataatttg agaaatgaaa
     1741 ctctcatctt atcggctctt tttgtttatc tgaattttac tgactagcct tcaatatttc
     1801 ttgcttcatt gatacctttt gctagtgctt ccattaagga tagttctttg tctgtaaagc
     1861 tatccatgta tttttctacc tgtaaccttc gagtgctttt aatcaaatta tctgtaggta
     1921 agaaaaattc atcaatagat acatggagta atgatacaag atcatacagc acttgtgtac
     1981 ttgggtgttg tcctttgttt tctatatttg ttaaataacg tgggtcaatt tcaatcattg
     2041 ttcccacttg ttcacgagtg agaccccgtt tcattcgagc ctctttaatc gctaaaccaa
     2101 cggctctaaa atcgtattta tcttcttttt tacgcatact aaatcacctc tatacatttt
     2161 actgttccta tataaccata aacaggtata gaaaaacatg ttatatagtt tatgagttcc
     2221 tatagaacac tgtggaattt attaatgcga tgaatccaat ttcaaataga aaggtcgctg
     2281 attttattta cctatacaac tttataaaat ttagtcatac tcctagaaag tagataaaat
     2341 tggcgactta atggagggaa aagtcgccat gagaaagata atctgtcatc tagttctctt
     2401 aattaagttc ttatcaaaaa aacttatcca cctgtactgg atagatatga ccatcaatgt
     2461 ggttttgcag attacataga tagaaaaatc aaagcatatg aacagagaaa acaatctgtt
     2521 tatgtgcttt tttggtcact taataaatat cttttaggat ttctcttcat ttatgcaaca
     2581 aatcccccgt tcgtgtcggg gtttagtatg aagggagata aagaagcaca tgccactccc
     2641 tttcacgaca gaaagggggt gaaaagcatg aaaccatctt cttttcaaga aaccatagaa
     2701 aatcagtttg actatatctg caaacaagtt attgaagatg aacgaaaaga ttacttcaaa
     2761 catctagaca gactatcagc aaaagaagtc tcgttttctg atatagataa ctaccttgtc
     2821 aactcttttt ctactgttga tacgtacgtc actgatttcc aactatttaa attatttgga
     2881 ttaagaatca atgttgaaag tgatttatta agtgaagccc tgcgtcatct ttcagagaaa
     2941 aaacggaaca ttattttact tcattacttt atggatatga gtgatgtgga gattgcggag
     3001 ttactaaatt tgaatcgttc gactgtttat cgtcatcgaa taagtggact agccatgatt
     3061 aaagaattca tgaaggagtg taaagaatga aaacagctta tccaagggtt cccttccccc
     3121 tcattgtaaa ggcgacagat ggcgacgtgg aagcaattaa tcagattgtt aaacattatc
     3181 gagggtatac ctcaaaacgt tcattacgtc gcatgacaga cgaatatgga aattctcata
     3241 tggttattga tgaaacccta cgtggcagaa tggaaacgaa actcatctct aagattttat
     3301 cgttcgaaat taaatagtcc cattttttcg tggaagcgtg tcgaatcgta tccacgcttc
     3361 ccgatttggg aggtttgtta ttccatcaaa gcatattgtg tgttcagtag gttttgatag
     3421 gctaacaagc caaacgttct ttgacaacca aataaaggca atcgaatacg tttcggtaag
     3481 aaaagagctg atgaactaac acgccatgac ctacaaaatt agtgagcgat tcatgttagt
     3541 aattcgaaag taatctttag caggattgct gccatgactt tcttatcgtg ataatgatac
     3601 tcccgtatag ccatagtccg agcgttagaa gcgtcacagg caatgggtac ggctacatga
     3661 gaaccatgca gaagtgaaat tcctgtgagc tttgctagag ctgttcgatt gctaagatat
     3721 tcttctcttg tcagtgtatt attataaaac tatttgatat aattataggt gaatattgga
     3781 gttttcctag cctataattg ggaaaggagt aataatgata acggtcacaa aaaaggattt
     3841 agttgagcta ggatatggaa cttctttttc agcagacatc ataaaaaaag caaaagaatt
     3901 gatgattaca aaagggcata tctactatca atctcgaaag ctagatagag tccctcgtga
     3961 agctgttgaa gaaattctag gaattcggtt ttcaaatgaa aacaggtctg agtagttttt
     4021 gcacagtaag gagtaaaaac tatggttaaa gacccaataa aaaaagcaaa gaatggaacc
     4081 tattattttc gtgcaaatct aggttatgat tctaaaggga aaaaaattca aaaatatcgt
     4141 agtggattca ctactaaaaa agaagcaaga gaagaatatt cgaaactgct attgatgaaa
     4201 ccagaagaat taagtgagaa taaggataaa atgacgttta aacattatat ctttgaaatt
     4261 ttccttccat ggtataagac acaggtaaag ctcagaacat atgaaaatcg cttaccaact
     4321 attaagaagc atttctctta ttttgataaa atggctgttt ccgatattga gcctattgat
     4381 gtgcaaaatt ggcaactaaa attatcaaag aagtgtaagt cttcttatgt aagagctgtt
     4441 caaggactat tttcagttgc tatggatcga gcaattgtcc ttgggataac caccacaaat
     4501 ccatctaaga ttattggcaa tgtgaaaaag caaaagtcta aaattgaatt ttggacaaaa
     4561 gaagaatttg aaaaagtaat ctctctaatt tacaaagaag attactatca acacttttta
     4621 tttatctctc tgtggttttt atttatgact ggaatgcgaa ttggtgaagc tactgccatt
     4681 caatgggaag atattgattt tgactcagga gtactaacca tcaacaaaac actctattac
     4741 aagaatcaat cgaattatag atttgttgaa ccaaaaacaa aggcgagcgt tcgtcatatt
     4801 gtattagata aatgcacatt aacttattta tccgaatgga aggaagtaca acaaaatcta
     4861 attcagacag actttgtaat gagctataac ggtattccta cccaaaaaca tacactatca
     4921 tatgctattg aacgctatgc taagctggct ggtatccatc gaatcagaat ccatgggtta
     4981 cggcattctc atgcttcctt gttaatcagt atgggagaaa atccacttat cattaaagat
     5041 cgtctaggac acgaagatat tgagacgact ttaggaacgt atggacatct ttatcctaac
     5101 agtaatttcg aggtagctaa caaattaaat ggagccattt cctttaaaga agcaaaacaa
     5161 aattatgata cttcaccaaa gaatcaattt actgtagact acttgcgaaa caaagaaatg
     5221 aaaaaagtgc aataaaagtg cagtaaaaag ataagaagag ccagaaaccc ttggtataag
     5281 aggatttcta gctctcctac aactattccc actccactgt tgctggtggt ttagaagtga
     5341 tgtcatacac gatacggttg acgtgggcta cttcgtttac gatacgtaca gagatttttt
     5401 gcaagacttc ccatgggata cgggcaaagt cagcggtcat tccgtcgatt gaagttacag
     5461 cacggatacc gactgtgtag tcgtaagtac gtccgtcacc cataacaccg acagagcgga
     5521 tccctggaag aacagtgaaa tattgccaga tatcacggtc aagtccagca gctgcgattt
     5581 cttcacgcaa gatagcatca gattcgcgta cgatttctag cttgtcttca gtgatttcgc
     5641 caagaacacg aataccaaga ccaggaccag ggaatggctg acgccaaacg attgaatcag
     5701 gcatgcctaa ctgagtccct aattcacgga cttcgtcttt gaataatgtg tttaatggtt
     5761 cgatcaattc aaattgcata tcttctggca gtccacctac attatggtga gatttgatcg
     5821 tctgtgctgt ttctgtacca gattcgataa cgtcagtata caacgttcct tgtgctagga
     5881 aagagacgcc ttcttcacca gcaagttttg ttgcttcgtc atcaaaaaca tatacgaatt
     5941 cattcccaat gattttacgt ttttgttctg ggtcagatac acctttcaac ttgtctaaga
     6001 agcgatctct tgcatcgact ttgatgatgt tcaagccgaa ttttccgcct agactttcca
     6061 ttacttgttc cgcttcgcct ttgcgtagca gaccgtggtc aacaaagata gatgtcaatt
     6121 ggtcaccgat cgctttttgt aaaagaaccc caacgacact agaatcaacg ccacctgaaa
     6181 gaccaagcaa gacttttttg tcaccaactt gttcacggat tttttctact tgcatatcga
     6241 taaagttatc cattgtccag ttaccttcac agtgacaaac atcaaaggca aagtggcgca
     6301 gcaattcgat tccgtattcg gaatgacgta cttctgcatg gaattggata ccataaaaat
     6361 tacgtgttgt gtcttggata gaagcaatcg gacaatcttt gcttgttccg actgtttcaa
     6421 agccttcagg aactttagtt accaagtcac catggctcat ccatactgtt tgttgttttg
     6481 gtgtttcttt aaacaagaca gcttgatcgc ttgttacttc taacaaggct ttcccatatt
     6541 cgcggttttt agcaggctct acggaaccgc caagtttgta cgtgatcaat tgcataccat
     6601 agcaaatccc taatacagga atacctaaat tgaagatctc aggatcgatc ccaaatgcat
     6661 tctcatcata tacactgttt ggtccgccag aaagaatgat tccctttgga ttcatcgctt
     6721 ttacttcttc tgcagtaatg cggtggctca ataattcgga aaagactcca agatcacgaa
     6781 tacgtcttgt gatcaattgg ttatactgac taccgtagtc taatacgata atcttttcaa
     6841 cgttcgtcat atcggcaacg tttgtcaaat ttattacccc tatcccttta aattttatct
     6901 caaaatagtc aaactatttt aaaatgctaa tattttcgca tgaaaatcga atcgatgata
     6961 tgattttcag ttttatggag aattatatcg gctcttcctc gtgtaggcaa gatatattcc
     7021 tgtaaatttt tcaaattcac atttttccat acatcttttg ccattttaaa ggcttcttca
     7081 cgatctccga tagcaaaacg ataataataa ttctctggat tttggaaagc cgtatccagt
     7141 aacgcaccaa aacgatccaa ataccatttt tcgatcagca cgggatcggc atcgacatag
     7201 acagaaaaat caaaaaagtc gctgacgtag atttgctgat tcgcaggtaa ttgaagcgta
     7261 ttgatcccct caacgatcaa gatatcaggc tgctggatca attcgtactt gtctggaatg
     7321 atatcataca catcatgtga gtaaacaggt acttttatct cttcctgacc agattttaca
     7381 cggttcaaga aatcgatcag catctccata tcataacttt caggaaatcc tttacggtcc
     7441 atgattccac gctcttttaa tatacgattt ggataaagaa atccgtcagt cgtgatcagc
     7501 tgaacgtttc ttcgtttgaa ggtacgagac aaaatcgtct gcagcagtct ggctgttgta
     7561 ctttttccaa cggctacact tccggcgatc ccgataataa aaggcggtac ttctacgtat
     7621 ttatgaagaa ataaaccttt actcaagaac aaagattcaa attctttcat ataaagataa
     7681 atcagatgag caagaggtac atagatatct cgaacatcct gcatggaaat gcggtcattc
     7741 aaacttttga tattatctag ttcatcttgt gtcaaaggtg cttgcccatt acgataaaat
     7801 tctcgccatt cttctcttgc cacacggtag tagttcattg gatcattcat attagcctcc
     7861 tgcgttctcc catcaatgga actattttaa cacaaaataa acgcaaaccc caccacttaa
     7921 gagagattgc cgatcttttt gtataatctt tataatagaa agaaacggag tcttattctt
     7981 gacttgcgca cggatacata aaaggataga ctgttgtcat gaaagaaatg agaaggatgg
     8041 aagacatgac aaatcattac tattctgaac gcccagatac ggcgcacgat tttgaacaat
     8101 gggcttttga gttaaaaggc agaacctttc aatttgtaac agattctggt gtattttcac
     8161 gtgaaacagt ggattatggt tcacgtgtcc tgattgatgc tttcgattgg gaagagttac
     8221 ctgatgaagg aaagatctta gatgtgggat gcgggtatgg accgattggg ttagctttgg
     8281 catttgcgac acagcggttt gttgaaatgg tcgacattaa tgaacgagcg gtaagtctag
     8341 cgcaaggaaa cgcaaagcgt aaccaaatcg aacatgttga tatccatcaa tcgaatatct
     8401 atgaagcagt tcatgaagaa acctatgcag ctatcgtaag caatccgccg atccgtgctg
     8461 gaaaaaaagt tgtacatgaa attttgacag gcgcatatcc tcggttgaag aagggcggta
     8521 cactgacaat tgtgatccag aagaaacaag gagcgccgag tgcgcaaaag aaaatggaag
     8581 aaacatttgg taatgcagaa atcgtcacaa aagataaagg atattatatc atcaaaagtg
     8641 tgaaagaata actagctgaa aaatagtgga gcgacgaaag agtggaactg ggcgtgcatg
     8701 tacgggtacg tatcagttct ttttttgttg agaagttttt aaaaacaaag aactattttt
     8761 tcttcaaaaa gaaatagtag gaacagagtc gttgtttttt acgataaaat aaataagata
     8821 cagaacttgt atagaaggct gccaagtcgg tagataaagg aggtttttat caaaaaacat
     8881 actttccttt tttctctatt cttttcttgg gggttttggt acactgatag ggaatttaga
     8941 tagaagggag ccaataggat gaagctgacc atcagagata tcgcagaaat ggcaggcgta
     9001 tcagtaacaa ctgtctcaca gattttgaat aacaaaggaa gcagatttag tgataagaca
     9061 agaaaaaaag tgttgtcgat cgtgaatgaa catcattata agcccgatta tttcgcttca
     9121 aatgtgatca atcgacattc aaagaccatc ggaatgatcg tccctgatgt cactgatttc
     9181 ttcttctcca aactgatcga aggtgtagag agctatttga atcctttggg ctatgtgatc
     9241 atgttatgca attctcgtca tagccaagaa aatgagatca agtatttaca agagctttcc
     9301 caccgctcag tggacggaat cttgctggcc acaccaaata ttttacctga gaaatatgca
     9361 ttagacagcg gtttttatca aaaaatgcca atcattttaa tcgatcgcgg attgaatcgt
     9421 cgggataacg gacggcttat cgtaaaggaa tatgagggcg cctatcaagc tgtttcgctg
     9481 tttattgaaa atggccatac gaagatcggc atgctgaagg aaaccactgg atactatcaa
     9541 ttagaagaac gtttcaacgg atatcgtcat gcgctgaaag atcatggcct gccttttaat
     9601 gggaaatttg ttgaacatgg agagttgact gtccaaggtg gatatactgc atcaaaaaaa
     9661 ttactcaaac ataaagatat cacggctatt ttttgcggga atgatgccat ggcgatcgga
     9721 tgctatcagg cgatcgatga attgggcaaa aaaatcccag aagatatctc agtcatagga
     9781 ttcgatggat taaagctgtc agaatacatg attccgcaat tgacgacagt gcagcagcca
     9841 agttttgata ttggatttta tgctgcacgt ttcctgatcg atacgatcga atttcctcaa
     9901 agaaaagttc cgaacaaagt gttcgaaaca aaattaatta ttcgtgagag cgtaaaagta
     9961 ttgacaaagg gctaactcgg cggtatattg cttatgtaag catttacaaa ggctagttag
    10021 tgcttttttt atttttagta aaccagttta ctaaagtggt ttacctttcc taaaaataat
    10081 gtataatacc gaatgaagac aaggaggatc aggcaatgcg aatggtggat ctgattgaaa
    10141 aaaagaggga tggaaacgag ctgtcgaaag aggaaatcga gtacatcgtc acgaactata
    10201 cgaatggaaa gattccagat tatcaagtca gtgcattatt gatggcaatt ttttatcaag
    10261 acatgacaaa tgaagaaatc acgaacttaa cattggcgat tgctaattct ggtgatgtca
    10321 tcgatttgag ttctcttgaa ggaataaagg tagataagca ttcgacaggt ggcgttggtg
    10381 acacgaccac attgatttta gcccccctag tagctagtgt cggagtgaca gtggctaaaa
    10441 tgtctggacg cggtctaggt tacacaggtg gtacactaga caagctagaa gcaattcccg
    10501 gatttcagat cgagctttcg gatgaagaat ttgtacgcat tgttaatgaa agtaaagtag
    10561 cggtaattgg tcaatcagga aacttggcac cggcggacaa aaaattgtat gccttgcgtg
    10621 acgtcacagc gaccgttgat tctcttccgc tgattgccag ttcgattatg agtaaaaaaa
    10681 tcgcggcagg agcagatgca atcgttttgg atgtgaccac tggagacggt gctttcatga
    10741 agaacatcga agatgcaaga cgtctggcaa agaccatgac gagcattggg aaactggcta
    10801 accgagaaac agtggcggtt atctcagata tgtcagaacc tcttggcgaa gctatcggaa
    10861 atagtctaga agttgtcgag gcaatcgaaa cattacaagg aaatggtcca gaagatctag
    10921 tagaaatgtg ctacgcctta ggaagccaaa tggttgttct tgctggcaaa gctaagacaa
    10981 ccgatgaagc aagaacgttg cttcaagaag ctctggaatc aggtaaagcg ttagcaaaat
    11041 tcaaagaaat gatccaaaat caagggggag acccagcgat cgtggaacat ccagaacgaa
    11101 ttttgactgc acgctacaca atggagcttc ctgctaaaca aagcggagtt gtgtcaaaaa
    11161 tcgtggcaaa tgaattagga attgctgcaa tgatgctagg tgctgggcgt aaaaccaaag
    11221 aagaagatat tgatcacgct gttggattga aactgcataa aaaaattggt gacactgtga
    11281 caaaaggtga gtcactattg acgatctata gtaacgacga agaaatcact tctgtcattg
    11341 aattattata taaaaatatt gaaattggtg aatc
//
LOCUS       DACGDM010000293         6075 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.131, whole genome shotgun sequence.
ACCESSION   DACGDM010000293 DACGDM010000000
VERSION     DACGDM010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.131"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            <1..2214
                     /locus_tag="IXR05_003131"
     CDS             <1..2214
                     /locus_tag="IXR05_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4261541.1"
                     /translation="WIVIKNTEFSIGKNRRWFGGILFYFGILLLLHAHLFGKLHTGEP
                     NIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYFLIAQPGSYLAAVLLLAGGAF
                     LFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAAKEERMKQRAEAKEARRLAAK
                     EAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPIDSFQENIHPANLEKP
                     VPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPTVDLLDSIPTVDQSDE
                     YKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIAL
                     ALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNHPDKLLEVPLGRDVSG
                     RVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEVKLMMIDPKMVELNMY
                     NGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNISGYNEFVQQKNLENG
                     TKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVIT
                     GIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLPMGENKPIRVQGAFIS
                     DHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELFEEAKALVVEMQTASI
                     SLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQEETSETLPDDNDM"
     gene            2444..3511
                     /gene="rlmN"
                     /locus_tag="IXR05_003132"
     CDS             2444..3511
                     /gene="rlmN"
                     /locus_tag="IXR05_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAQ4261542.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(3704..4807)
                     /locus_tag="IXR05_003133"
     CDS             complement(3704..4807)
                     /locus_tag="IXR05_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4261543.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            5360..5908
                     /gene="aac(6')"
                     /locus_tag="IXR05_003134"
     CDS             5360..5908
                     /gene="aac(6')"
                     /locus_tag="IXR05_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4261544.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2016 a         1052 c         1313 g         1694 t
ORIGIN      
        1 tggattgtca ttaagaatac agagttttca attggtaaaa accgacgctg gtttggcggc
       61 atactctttt atttcggtat cttattattg ttacatgccc atttatttgg caaactccat
      121 actggggaac caaatatcat ggggacgaca tgggatttgt tagccagtga tataaaacaa
      181 agtcaagtag acaataacgt tggtggtggg atgattggag caatccttta tcattttact
      241 tacttcttga ttgcacagcc tggaagttat ttagcagcag tgctattact ggcaggagga
      301 gcattcctgt tcagtaatct ggaaggctat cagctgttaa atggtatcca atcaattgga
      361 gaacgagtac aggaattatt ggaaggtgat cctgccaagc aagctcgaaa gcaagcggca
      421 aaggaagaga gaatgaaaca gcgcgcagaa gcgaaagaag caaggcgctt agctgcaaaa
      481 gaagctgcag aaaaagaagc tgcagaatat gagaagaaaa aagcggtgag ccagcaaagg
      541 gaaaatactg ctgatgaatg gcaggaacca gaaaatacag agccggagca gctaagtttt
      601 gttccaatcg acagttttca agaaaatatc catcctgcga atctagagaa accagtacca
      661 gatacaccaa aacagaccaa tacagcagaa ggtttttcag atgagttgcc agaggatgac
      721 ggtacctcat tagaatttga gattgaagca gaacaggaaa atcaagacta tgaattaccg
      781 acagttgatt tgcttgattc tataccaact gtggatcaaa gtgatgagta taaaaaaatt
      841 gaaaaaaata tcggcgtatt agaacaaact ttccaaagtt tcggtgtcga tgccaaggtc
      901 gtcaaagcca gcttaggacc atccgtcaca aaattcgaag tccagccggc tgtaggggta
      961 aaagtaagta aaattgtgaa cttaacagat gatatcgcgc ttgctttagc ggcgaaagat
     1021 gtccggatgg aagcaccgat tccaggtaaa tcactgattg gtattgaagt accaaatgga
     1081 aagatcagta tggtttcctt tagagaaatc atcgaagcac aaccaaacca cccagataaa
     1141 ttactagaag tacctttagg acgtgatgtt tctggacggg tacaaacggc tgatctttcg
     1201 aagatgcctc acttactcgt ggctggttcg actggtagtg ggaagtcagt agcaattaat
     1261 gggattatca caagtatatt aatgcgtgct aagccccatg aagtaaaact gatgatgatc
     1321 gatccgaaaa tggttgaatt gaatatgtac aacggcatac ctcatctgtt gacgccggtc
     1381 gtgacgaacc ctagaaaagc agcgcaagcc ttacaaaaag tagtacaaga aatggaagaa
     1441 cgatatgaaa aattcgcggc aaccggagta agaaatattt ctggttacaa tgaatttgtt
     1501 caacagaaaa acttggaaaa cggaacgaaa catccaacct taccattcat cgtagtgatc
     1561 gtagatgaat tagctgattt gatgatggta gccagcaatg aagttgaaga tgcgattatt
     1621 cgtttagcgc aaatggctcg ggcagcgggg attcatatga tcctagctac tcaacgtcca
     1681 agtgtggatg ttatcacagg aatcatcaaa gcaaatgtac cttccagaat ggcatttgcg
     1741 gtatcaagcg gtacagattc tcggacgatc attgattcta atggggcaga aaagctctta
     1801 gggcgaggag atatgctatt cttgccaatg ggtgagaata aaccgatccg tgtgcaagga
     1861 gcattcattt ctgaccacga agtagaacgg gtcgttcaat ttgttacaga tcagcaagaa
     1921 gctcattatg aagagaaaat gatgccgaca gatgaagttg aaacgacagg tgctccagaa
     1981 cagccacaag atgagctgtt tgaagaagca aaagcacttg tcgttgaaat gcaaacggca
     2041 agtatttccc ttctccaaag aagatttcgg atcggttaca accgagcagc acgtttagta
     2101 gatgaactgg aagctcatgg agttgttggc ccgtcagaag gaagcaagcc tcggaaagta
     2161 ttcattgagc aggaagaaac atcagaaacg ttgccggacg ataatgacat gtaaaacttg
     2221 tgtgatgaag ggttgaaaaa cgaataacca ataaaaagac aaggcatgat gataccaaaa
     2281 gaaaaaatgg tttttttcca tcttttctaa tacggtatga tgtcttgtct ttttagtttt
     2341 tgtgagatta aagttctatt cgatttattt gtgaagtatt gcattaagga aatgaatcat
     2401 gtatagtatg tagcgaaact ttgagaaaaa gagggaaaat actttggaaa aacagtccat
     2461 ttatggcttg acgaatgaag aattaatcaa ttggtttata gaaaacggcg agaaaaaatt
     2521 ccgagctgcc caagtttggg aatggttgta tcaaaaacgt gtaagtaatt tcacagaaat
     2581 gacgaatcta tcgaaacaat tgatcgaaaa attatcggag cattttatca tcaatcctct
     2641 aaaacagatg gtcgtccaag aagcttcgga tggtacagta aaatatttgt ttgaactccc
     2701 tgataaaaac atgattgaga ctgtactgat gagacaagaa tatggcttgt cagtttgtgt
     2761 gacgacacaa gtaggatgta atatcggctg tacgttttgt gcaagcgggc tgctcaaaaa
     2821 gaaccgtgat ctgactgctg gagaaattgt tgcacagatc atgatggtcc aacattattt
     2881 tgatgagcgc aatcttggcg aacgcgtttc acatgtcgtt gtaatgggga tcggtgagcc
     2941 atttgataat tacgacaatg taatggactt tttgcatatc atcaatgatg ccaaaggatt
     3001 ggcaattggt gctcggcaca ttacagtttc cactagtgga ttagcacaca aaatcaagga
     3061 attcgctaat aacggcttgc aagtcaatct ggctatttcc ttgcacgcgc cgaataatga
     3121 ggtgcgaaca tcgatcatgc ggatcaaccg aagtttccca attgagaaat tgatggaagc
     3181 tgtggatgag tatttagaga aaacaaaccg tcgaatcacg tttgaatata tcatgttgaa
     3241 tcaagtaaat gatagaccag agcatgcgca acaattagca gatctattaa aagataagaa
     3301 aaaattagca tatgtcaact tgattccata taatccagtc agtgaacatg atcaatattc
     3361 tcgcagtcca aaagctgatg tattgagatt ttatgatgta ttgaagaaaa acggcgtaaa
     3421 ctgtgtgata cgtaaagaac atggtacaga tattgatgca gcttgcggac aattgcgaag
     3481 caagcaaatg aaaaaaacag ttgccaaata atcgtatcct actcgttttt tcaattacca
     3541 taaaaggagc agttttctta attaaggaac tgttcaactt aaataagaga aaagattcta
     3601 tagcgaaagc tataaagctt tttttgacaa gaaaaaccct catcaagcaa agaaatgtcc
     3661 tcaatttgat gacagcctgc ttgatggggg ttttagcaat tatttaactg attttcttat
     3721 atccttgctg gctttcttgt gtagcatgat aagtttctac gtcaagaatg gcctgtttaa
     3781 atttttctcg ggtgatttca taaggcacat gtttaatatc atttgttgcc atggctttat
     3841 ctaagattgc ttctaaatcg gtcgtgacat tgagattcat gtcggttaac gatactggaa
     3901 gttggttctt tttcataaac acatagattt tatcaaacaa atcgaactgc tgatccatca
     3961 tcaataaggt cagtacacca taactgacag atgctccgtg aaggtatccc tccatttttt
     4021 ctagaacagt cgtaccgtaa tagaatgagt gtgccatagc agaattatag ttattgttaa
     4081 ctaaaacaga aaccaatccg gtagtaacaa tgatatccga aacgacttgt tcaattgcat
     4141 atgagggacg atcgtcggca ctatctttca atgcttgcgt accataagtc aagagacgat
     4201 caatgcacat ttttccgatt tggattccta atctatccgt gtagcctaga tcatcgccac
     4261 gagcagaaaa agtagattcg acttctttgg ataaagcatc gccaatacct gcccataagt
     4321 atttatcagg tgcttcggca ataattgctg tatcaatgaa ggtgtgtaca ggtggttttg
     4381 aaggaaagaa gagtccgtcc attacgcctt cttcgttata gatgacacat accgcagtga
     4441 cgggcgaaca gttcgaacca atagtgggaa aggtgaagac tggtttagct agtttttcac
     4501 caatgacttt tacagtatcg caagcacggc caccaccgac tgcaaacagg acgtctgctt
     4561 tttggacact ttcatgctgg atcaactgtt caatatttcc ataagttgaa ttacccccgt
     4621 accagagact ggcgacaacc tctatttcct gtgtcaaagc tacttttatt ttgttttctg
     4681 cctttgaaag tgcagtcttc cctccaatca gcactacttt tgtcccatat tctttgacga
     4741 ttccatttgc tttttcatac gcatctgttc caatggtata atttggtaag aaaacacttt
     4801 gactcatatt catttccttc tttcttcgtt gaaacgggtt aaaattttaa agagtgatcg
     4861 atctgactgc ggctgtagat ggagtagagg tgaacctaag acaggataag tgatgaataa
     4921 ggtggcatga acaccttgaa atcatcaata agtatcctaa aaacgaacaa gtacaaaaac
     4981 attgaaaacg acaataatga atttttgttc ctcttagtat ttctaccgat tccctttgct
     5041 tttttgtaat tatctaaaaa ttctaaaaat taagattatt atatgaaaac aggttttatt
     5101 tgtcaattca taattggttt tttttaaagc aaaagataat ctatatcatg atgaacaaac
     5161 agagtttttt cctccaattg atggctttcc tgatctttcc tattttgaat aaagtgtttc
     5221 tgtataattt ttttatttta taagtaagat aaataatgaa agaatagaga tactgattgg
     5281 tagctaaaga tttttgagcg agaacatttc gttttttcaa aaggactgtt agaataagca
     5341 agaacaaggg ggaagacgta tgataatcag tgaatttgac cgtaataatc cagtattgaa
     5401 agatcagctt tctgatttac tgagactgac ttggccggaa gaatatggag acagctcggc
     5461 agaagaagta gaagaaatga tgaatccaga acgaatcgcg gtagcagcgg tagaccaaga
     5521 tgagttagta ggatttattg gtgcaatccc tcaatacggt atcacaggtt gggaattgca
     5581 tccattagtt gtagaaagct cccgacgaaa gaaccaaata ggtactcgat tagtcaatta
     5641 cttagaaaaa gaagtagctt ccagaggagg aatcacgatt tatttaggta cggatgattt
     5701 agaccatgga acaacgttaa gtcaaacgga cctgtatgag catacatttg ataaagtggc
     5761 ttccatccag aaccttcgtg aacatccgta tgaattctat gaaaaattag gttataaaat
     5821 cgtaggtgtc ttaccaaatg caaatggctg ggacaaaccg gatatttgga tggcaaaaac
     5881 gattattcct cgaccaaatt ctcaataata aaaagaggtt gtgacagaag taatcagctt
     5941 caagaaataa gaaggaattt acgaaaatta cttcttgaat ttttgtgaaa ttccaactta
     6001 tttccgaaga agctactttt ggaacaccgt gtaccagagg ttgtgaaaaa gtcgcttagt
     6061 ttcgagtagt aagaa
//
LOCUS       DACGDM010000294         5985 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.133, whole genome shotgun sequence.
ACCESSION   DACGDM010000294 DACGDM010000000
VERSION     DACGDM010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.133"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            complement(40..1026)
                     /locus_tag="IXR05_003135"
                     /pseudo
     CDS             complement(40..1026)
                     /locus_tag="IXR05_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701269.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
     gene            1178..1873
                     /gene="vanR"
                     /locus_tag="IXR05_003136"
     CDS             1178..1873
                     /gene="vanR"
                     /locus_tag="IXR05_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAQ4261545.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1851..3005
                     /locus_tag="IXR05_003137"
     CDS             1851..3005
                     /locus_tag="IXR05_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAQ4261546.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            3220..4188
                     /locus_tag="IXR05_003138"
     CDS             3220..4188
                     /locus_tag="IXR05_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAQ4261547.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            4181..5212
                     /gene="vanA"
                     /locus_tag="IXR05_003139"
     CDS             4181..5212
                     /gene="vanA"
                     /locus_tag="IXR05_003139"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAQ4261548.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            5218..5826
                     /locus_tag="IXR05_003140"
     CDS             5218..5826
                     /locus_tag="IXR05_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAQ4261549.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1811 a         1161 c         1347 g         1666 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaacccta tttccgataa ccgtgtattg
       61 aaaggcatct tcgaagccat tatccaatat ttcgcaggct tttgtatatt taggctggtc
      121 gatatattca ccgactaagg cattcttagc tgttcgagcg agttcaatat ccgtaaactt
      181 aaagatcgct tttactgctt ctctaaacgg ttttgaattc ttttttggaa tggaactgaa
      241 gatgtttctt aaaaaatgga cctggcatct ctgccaactt gcgttggtaa atgacttacg
      301 aatcgcagac actaggcctt tatgggcatc agaaatgatg agttctgtcc cctttaggcc
      361 gcgttctttt aagtattcaa agaagatgga ccatgtgtca tcactttctt cattttgaat
      421 catgaagcca atgatttcac ggtcgccacc ttctgttatc ccgatcgcaa tatggcagct
      481 tttagaaagc actcgatggt cctcacggac ttttatgtag agaacatcag tcatcagata
      541 aggataattc gtacctgaga gtgaacggtt ctgccattcg ttgaccatcg ggtctaactg
      601 ctcagtcagg ctagaaacaa aagatttcga tacagatttt ccacatagct cttcaacaat
      661 ctttgaaact ttacgtgtcg aaacgcccga aacatacatc tcaagcattg aagcgagcag
      721 tgccttttca tttcgctgat aacgctcaaa caccgtcggt gaaaattcac catcacgtgt
      781 tctaggcact tttaattcga gtgtacccac acgagtcgta aagtctcgct cataatagcc
      841 atttctttga ctctgacgac tttctgaacg ttcatagtca tcggcttgaa tatattctgt
      901 tcgttgattt tccatcaatt ggttgaaaac agtggttaaa atatttttag aaacatcatc
      961 ttttaccgaa tgttcaataa tactttgaac ctcttcgttg ttcagtgtaa aatgtacttg
     1021 ggtcatgtaa cgtcctcctg ggtatgtttt tgtggttaaa aacattgtac cgtaaaaggg
     1081 ctgttacatg gccttttatc ttttacacaa ttatatggac tttatcctat aatctgataa
     1141 attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa tacttattgt
     1201 ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg agaattatac
     1261 ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt ctgagattga
     1321 ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct gtcaaaaaat
     1381 aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag aggtagataa
     1441 aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc gcccactgga
     1501 gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg gagtaaagga
     1561 gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca cccatgagtg
     1621 ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac tgcgaatcct
     1681 ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga tatggggcga
     1741 cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt tgcgcgaaaa
     1801 aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg ttggttataa
     1861 aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac atgtatatcg
     1921 ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg atccgaggga
     1981 aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat cacctggacg
     2041 cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt tatgtggcga
     2101 ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca aaatactttg
     2161 acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa attgagcttt
     2221 ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact ctggaaaagc
     2281 gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg tacttggcgc
     2341 acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt gacgaggctc
     2401 cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac aaagcgtatc
     2461 gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta caaacgataa
     2521 cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc gatgaatttt
     2581 atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag gatctgaccg
     2641 tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa aacgccgctg
     2701 catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg gatgtggtgt
     2761 caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc atatttgaaa
     2821 agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga cttggattgg
     2881 cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa agcaatgata
     2941 actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat aaaaggaggt
     3001 cctaagagat gtatataatt ttttaggaaa atctcaaggt tatctttact ttttcttagg
     3061 aaattaacaa tttaatatta agaaacggct cgttcttaca cggtagactt aataccgtaa
     3121 gaacgagccg ttttcgttct tcagagaaag atttgacaag attaccattg gcatccccgt
     3181 tttatttggt gcctttcaca gaaagggttg gtcttaatta tgaataacat cggcattact
     3241 gtttatggat gtgagcagga tgaggcagat gcattccatg ctctttcgcc tcgctttggc
     3301 gttatggcaa cgataattaa cgccaacgtg tcggaatcca acgccaaatc cgcgcctttc
     3361 aatcaatgta tcagtgtggg acataaatca gagatttccg cctctattct tcttgcgctg
     3421 aagagagccg gtgtgaaata tatttctacc cgaagcatcg gctgcaatca tatagataca
     3481 actgctgcta agagaatggg catcactgtc gacaatgtgg cgtactcgcc ggatagcgtt
     3541 gccgattata ctatgatgct aattcttatg gcagtacgca acgtaaaatc gattgtgcgc
     3601 tctgtggaaa aacatgattt caggttggac agcgaccgtg gcaaggtact cagcgacatg
     3661 acagttggtg tggtgggaac gggccagata ggcaaagcgg ttattgagcg gctgcgagga
     3721 tttggatgta aagtgttggc ttatagtcgc agccgaagta tagaggtaaa ctatgtaccg
     3781 tttgatgagt tgctgcaaaa tagcgatatc gttacgcttc atgtgccgct caatacggat
     3841 acgcactata ttatcagcca cgaacaaata cagagaatga agcaaggagc atttcttatc
     3901 aatactgggc gcggtccact tgtagatacc tatgagttgg ttaaagcatt agaaaacggg
     3961 aaactgggcg gtgccgcatt ggatgtattg gaaggagagg aagagttttt ctactctgat
     4021 tgcacccaaa aaccaattga taatcaattt ttacttaaac ttcaaagaat gcctaacgtg
     4081 ataatcacac cgcatacggc ctattatacc gagcaagcgt tgcgtgatac cgttgaaaaa
     4141 accattaaaa actgtttgga ttttgaaagg agacaggagc atgaatagaa taaaagttgc
     4201 aatactgttt gggggttgct cagaggagca tgacgtatcg gtaaaatctg caatagagat
     4261 agccgctaac attaataaag aaaaatacga gccgttatac attggaatta cgaaatctgg
     4321 tgtatggaaa atgtgcgaaa aaccttgcgc ggaatgggaa aacgacaatt gctattcagc
     4381 tgtactctcg ccggataaaa aaatgcacgg attacttgtt aaaaagaacc atgaatatga
     4441 aatcaaccat gttgatgtag cattttcagc tttgcatggc aagtcaggtg aagatggatc
     4501 catacaaggt ctgtttgaat tgtccggtat cccttttgta ggctgcgata ttcaaagctc
     4561 agcaatttgt atggacaaat cgttgacata catcgttgcg aaaaatgctg ggatagctac
     4621 tcccgccttt tgggttatta ataaagatga taggccggtg gcagctacgt ttacctatcc
     4681 tgtttttgtt aagccggcgc gttcaggctc atccttcggt gtgaaaaaag tcaatagcgc
     4741 ggacgaattg gactacgcaa ttgaatcggc aagacaatat gacagcaaaa tcttaattga
     4801 gcaggctgtt tcgggctgtg aggtcggttg tgcggtattg ggaaacagtg ccgcgttagt
     4861 tgttggcgag gtggaccaaa tcaggctgca gtacggaatc tttcgtattc atcaggaagt
     4921 cgagccggaa aaaggctctg aaaacgcagt tataaccgtt cccgcagacc tttcagcaga
     4981 ggagcgagga cggatacagg aaacggcaaa aaaaatatat aaagcgctcg gctgtagagg
     5041 tctagcccgt gtggatatgt ttttacaaga taacggccgc attgtactga acgaagtcaa
     5101 tactctgccc ggtttcacgt catacagtcg ttatccccgt atgatggccg ctgcaggtat
     5161 tgcacttccc gaactgattg accgcttgat cgtattagcg ttaaaggggt gataagcatg
     5221 gaaataggat ttactttttt agatgaaata gtacacggtg ttcgttggga cgctaaatat
     5281 gccacttggg ataatttcac cggaaaaccg gttgacggtt atgaagtaaa tcgcattgta
     5341 gggacatacg agttggctga atcgcttttg aaggcaaaag aactggctgc tacccaaggg
     5401 tacggattgc ttctatggga cggttaccgt cctaagcgtg ctgtaaactg ttttatgcaa
     5461 tgggctgcac agccggaaaa taacctgaca aaggaaagtt attatcccaa tattgaccga
     5521 actgagatga tttcaaaagg atacgtggct tcaaaatcaa gccatagccg cggcagtgcc
     5581 attgatctta cgctttatcg attagacacg ggtgagcttg taccaatggg gagccgattt
     5641 gattttatgg atgaacgctc tcatcatgcg gcaaatggaa tatcatgcaa tgaagcgcaa
     5701 aatcgcagac gtttgcgctc catcatggaa aacagtgggt ttgaagcata tagcctcgaa
     5761 tggtggcact atgtattaag agacgaacca taccccaata gctattttga tttccccgtt
     5821 aaataaactt ttaaccgttg cacggacaaa ctatataagc taactctttc ggcaggaaac
     5881 ccgacgtatg taactggttc ttagggaatt tatatatagt agatagtatt gaagatgtaa
     5941 ggcagagggt tctgttgcaa agttttaaat aaagaataaa atccc
//
LOCUS       DACGDM010000295         1504 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.215, whole genome shotgun sequence.
ACCESSION   DACGDM010000295 DACGDM010000000
VERSION     DACGDM010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.215"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            262..373
                     /locus_tag="IXR05_003141"
                     /pseudo
     CDS             262..373
                     /locus_tag="IXR05_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            394..477
                     /locus_tag="IXR05_003142"
     CDS             394..477
                     /locus_tag="IXR05_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HAQ4261550.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            602..1339
                     /gene="erm(B)"
                     /locus_tag="IXR05_003143"
     CDS             602..1339
                     /gene="erm(B)"
                     /locus_tag="IXR05_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAQ4261551.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          551 a          224 c          245 g          484 t
ORIGIN      
        1 atttgtatcg ataagaaata gatttaaaaa tttcgctgtt attttgtaca tttaacttga
       61 cggtgacatc tctctattgt gagttattag tggtacagtt ttcaaccgtt ttaattataa
      121 aaaagtggtg catttttaaa ttggcacaaa caggtaacgg ttattgcagg tgtatttctt
      181 atctatgggt ttaacatgga ttttatcatt aaaatcatga gtattgtccg agagtgattg
      241 gtcttgcgta tggttaaccc taaagttatg gaaataagac ttagaagcaa acttaagagt
      301 gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta aattagatgc
      361 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgttatgta
      421 gataaaacat ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
      481 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
      541 acaaacaaat cgtttaactt ctgtatttgt ttatagatgt aatcacttca ggagtgataa
      601 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
      661 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
      721 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
      781 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat
      841 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
      901 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc
      961 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
     1021 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
     1081 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
     1141 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
     1201 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     1261 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
     1321 atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta
     1381 ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta ccaattaatt
     1441 cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc ttatcgatac
     1501 aaat
//
LOCUS       DACGDM010000296         1349 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.225, whole genome shotgun sequence.
ACCESSION   DACGDM010000296 DACGDM010000000
VERSION     DACGDM010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.225"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            46..297
                     /locus_tag="IXR05_003144"
                     /pseudo
     CDS             46..297
                     /locus_tag="IXR05_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            390..1184
                     /locus_tag="IXR05_003145"
                     /note="aph(3')-IIIa"
     CDS             390..1184
                     /locus_tag="IXR05_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAQ4261552.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          424 a          234 c          322 g          369 t
ORIGIN      
        1 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
       61 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      121 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      181 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      241 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      301 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      361 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      421 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      481 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      541 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      601 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      661 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      721 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      781 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      841 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      901 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
      961 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1021 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1081 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1141 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1201 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1261 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1321 cgcctacgag gaatttgtat cgataagaa
//
LOCUS       DACGDM010000297         1196 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.235, whole genome shotgun sequence.
ACCESSION   DACGDM010000297 DACGDM010000000
VERSION     DACGDM010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.235"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            259..>1196
                     /gene="vanY"
                     /locus_tag="IXR05_003146"
     CDS             259..>1196
                     /gene="vanY"
                     /locus_tag="IXR05_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAQ4261553.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNWFCCKVLNLLSN"
BASE COUNT          428 a          173 c          238 g          357 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaacccc cattgtcaac aggcagttca
       61 gcctcgttaa attcagcatg ggtatcactt atgaaaattc atctacattg gtgataatag
      121 taaatccagt agggcgaaat aattgactgt aatttacggg gcaaaacggc acaatctcaa
      181 acgagattgt gccgtttaag gggaagattc tagaaatatt tcatacttcc aactatatag
      241 ttaaggagga gactgaaaat gaagaagttg ttttttttat tgttattgtt attcttaata
      301 tacttaggtt atgactacgt taatgaagca ctgttttctc aggaaaaagt cgaatttcaa
      361 aattatgatc aaaatcccaa agaacattta gaaaatagtg ggacttctga aaatacccaa
      421 gagaaaacaa ttacagaaga acaggtttat caaggaaatc tgctattaat caatagtaaa
      481 tatcctgttc gccaagaaag tgtgaagtca gatatcgtga atttatctaa acatgacgaa
      541 ttaataaatg gatacgggtt gcttgatagt aatatttata tgtcaaaaga aatagcacaa
      601 aaattttcag agatggtcaa tgatgctgta aagggtggcg ttagtcattt tattattaat
      661 agtggctatc gagactttga tgagcaaagt gtgctttacc aagaaatggg ggctgagtat
      721 gccttaccag caggttatag tgagcataat tcaggtttat cactagatgt aggatcaagc
      781 ttgacgaaaa tggaacgagc ccctgaagga aagtggatag aagaaaatgc ttggaaatac
      841 gggttcattt tacgttatcc agaggacaaa acagagttaa caggaattca atatgaacca
      901 tggcatattc gctatgttgg tttaccacat agtgcgatta tgaaagaaaa gaatttcgtt
      961 ctcgaggaat atatggatta cctaaaagaa gaaaaaacca tttctgttag tgtaaatggg
     1021 gaaaaatatg agatctttta ttatcctgtt actaaaaata ccaccattca tgtgccgact
     1081 aatcttcgtt atgagatatc aggaaacaat atagacggtg taattgtgac agtgtttccc
     1141 ggatcaacac atactaattg gttctgttgc aaagttttaa atctactatc aaataa
//
LOCUS       DACGDM010000298          804 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate DMG1500794
            SAMN05449837-rid9572163.guided.262, whole genome shotgun sequence.
ACCESSION   DACGDM010000298 DACGDM010000000
VERSION     DACGDM010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05449837
            Sequence Read Archive: SRR3957293
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703493.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703493.1
            Genome Coverage       :: 105x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 18:03:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,147
            CDSs (total)                      :: 3,081
            Genes (coding)                    :: 3,000
            CDSs (with protein)               :: 3,000
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 30 of 81
            Pseudo Genes (incomplete)         :: 41 of 81
            Pseudo Genes (internal stop)      :: 19 of 81
            Pseudo Genes (multiple problems)  :: 8 of 81
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05449837-rid9572163.guided.262"
                     /isolate="DMG1500794"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2015"
     gene            2..>804
                     /gene="aac(6')-Ie"
                     /locus_tag="IXR05_003147"
     CDS             2..>804
                     /gene="aac(6')-Ie"
                     /locus_tag="IXR05_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HAQ4261554.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISD"
BASE COUNT          341 a           62 c          137 g          264 t
ORIGIN      
        1 aatgaatata gttgaaaatg aaatatgtat aagaacttta atagatgatg attttccttt
       61 gatgttaaaa tggttaactg atgaaagagt attagaattt tatgatggta gagataaaaa
      121 atatacatta gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag
      181 agtaattatt gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga
      241 tgagttatat actgattatc attatccaaa aactgatgag atagtctatg gtatggatca
      301 atttatagga gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat
      361 ttttgaattt ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa
      421 taatccaaga gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc
      481 agaacatgaa ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga
      541 tgataatgcc acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt
      601 caaagtagat agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa
      661 taatgaatac atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga
      721 aaaagcaata tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat
      781 tgaatattcg tatattagtg atga
//
